LH59_15645 4335384c680ae316ccd3fd51bca94d2f 398 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 120 3.4E-22 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 LH59_15645 4335384c680ae316ccd3fd51bca94d2f 398 SUPERFAMILY SSF56645 1 243 4.58E-76 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 LH59_15645 4335384c680ae316ccd3fd51bca94d2f 398 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 395 1.3E-23 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LH59_15645 4335384c680ae316ccd3fd51bca94d2f 398 SUPERFAMILY SSF47203 231 398 6.98E-25 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 LH59_15645 4335384c680ae316ccd3fd51bca94d2f 398 Gene3D G3DSA:2.40.110.10 124 234 5.7E-38 T 14-10-2018 LH59_15645 4335384c680ae316ccd3fd51bca94d2f 398 Gene3D G3DSA:1.20.140.10 235 398 3.5E-37 T 14-10-2018 LH59_15645 4335384c680ae316ccd3fd51bca94d2f 398 Gene3D G3DSA:1.10.540.10 1 120 5.7E-30 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 LH59_15645 4335384c680ae316ccd3fd51bca94d2f 398 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 219 1.6E-21 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 LH59_14040 d9ae591d3ab2f40e26cef4fd304d3fa0 263 SMART SM00382 26 213 8.4E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_14040 d9ae591d3ab2f40e26cef4fd304d3fa0 263 Pfam PF00005 ABC transporter 24 163 1.6E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_14040 d9ae591d3ab2f40e26cef4fd304d3fa0 263 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_14040 d9ae591d3ab2f40e26cef4fd304d3fa0 263 Gene3D G3DSA:3.40.50.300 1 252 4.3E-59 T 14-10-2018 LH59_14040 d9ae591d3ab2f40e26cef4fd304d3fa0 263 SUPERFAMILY SSF52540 1 226 3.65E-51 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_25030 7c453c91156a41be7bbf04ea128a6d31 469 Gene3D G3DSA:1.10.10.10 1 66 3.9E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_25030 7c453c91156a41be7bbf04ea128a6d31 469 Gene3D G3DSA:3.90.1150.10 98 466 2.3E-100 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_25030 7c453c91156a41be7bbf04ea128a6d31 469 Pfam PF00155 Aminotransferase class I and II 149 450 7.9E-31 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LH59_25030 7c453c91156a41be7bbf04ea128a6d31 469 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 66 2.9E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_25030 7c453c91156a41be7bbf04ea128a6d31 469 SMART SM00345 7 66 2.8E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_25030 7c453c91156a41be7bbf04ea128a6d31 469 SUPERFAMILY SSF46785 2 70 9.73E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_25030 7c453c91156a41be7bbf04ea128a6d31 469 SUPERFAMILY SSF53383 94 467 1.32E-91 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_25030 7c453c91156a41be7bbf04ea128a6d31 469 Gene3D G3DSA:3.40.640.10 143 361 2.3E-100 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_09065 a2927e9296f9103183998e1015a7a938 122 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 122 70.101 T 14-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 LH59_09065 a2927e9296f9103183998e1015a7a938 122 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 95 1.0E-46 T 14-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 LH59_09065 a2927e9296f9103183998e1015a7a938 122 Gene3D G3DSA:2.40.40.20 1 122 1.9E-52 T 14-10-2018 LH59_09065 a2927e9296f9103183998e1015a7a938 122 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 118 3.0E-52 T 14-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 LH59_09065 a2927e9296f9103183998e1015a7a938 122 SUPERFAMILY SSF50692 1 119 8.82E-48 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily LH59_09065 a2927e9296f9103183998e1015a7a938 122 Pfam PF02261 Aspartate decarboxylase 1 114 3.7E-49 T 14-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 LH59_09065 a2927e9296f9103183998e1015a7a938 122 PIRSF PIRSF006246 1 121 1.6E-51 T 14-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 LH59_14855 096755f3e35434d180bc875e9a827cb0 463 Gene3D G3DSA:3.50.50.60 58 417 9.7E-71 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_14855 096755f3e35434d180bc875e9a827cb0 463 SUPERFAMILY SSF51905 57 433 6.15E-44 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_14855 096755f3e35434d180bc875e9a827cb0 463 Pfam PF01266 FAD dependent oxidoreductase 58 418 3.4E-47 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 LH59_14855 096755f3e35434d180bc875e9a827cb0 463 Gene3D G3DSA:3.30.9.10 151 378 9.7E-71 T 14-10-2018 LH59_08185 7d1199f86dff373d29700c53cb1f15c4 479 SUPERFAMILY SSF52467 306 479 2.91E-75 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily LH59_08185 7d1199f86dff373d29700c53cb1f15c4 479 Pfam PF02233 NAD(P) transhydrogenase beta subunit 8 476 3.8E-191 T 14-10-2018 IPR034300 NADP transhydrogenase beta-like domain KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 LH59_08185 7d1199f86dff373d29700c53cb1f15c4 479 Gene3D G3DSA:3.40.50.1220 302 479 3.6E-83 T 14-10-2018 LH59_08185 7d1199f86dff373d29700c53cb1f15c4 479 PIRSF PIRSF000204 2 479 9.8E-212 T 14-10-2018 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2 LH59_06160 99adc0678c5cdeb18d130f03f879898a 678 Pfam PF00361 Proton-conducting membrane transporter 140 434 5.9E-86 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06160 99adc0678c5cdeb18d130f03f879898a 678 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 71 128 2.0E-25 T 14-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06160 99adc0678c5cdeb18d130f03f879898a 678 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 6 673 1.3E-241 T 14-10-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06160 99adc0678c5cdeb18d130f03f879898a 678 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 327 339 8.9E-66 T 14-10-2018 LH59_06160 99adc0678c5cdeb18d130f03f879898a 678 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 237 258 8.9E-66 T 14-10-2018 LH59_06160 99adc0678c5cdeb18d130f03f879898a 678 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 89 114 8.9E-66 T 14-10-2018 LH59_06160 99adc0678c5cdeb18d130f03f879898a 678 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 117 137 8.9E-66 T 14-10-2018 LH59_06160 99adc0678c5cdeb18d130f03f879898a 678 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 432 451 8.9E-66 T 14-10-2018 LH59_06160 99adc0678c5cdeb18d130f03f879898a 678 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 164 185 8.9E-66 T 14-10-2018 LH59_06160 99adc0678c5cdeb18d130f03f879898a 678 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 259 285 8.9E-66 T 14-10-2018 LH59_06160 99adc0678c5cdeb18d130f03f879898a 678 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 91 111 7.3E-14 T 14-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 LH59_06160 99adc0678c5cdeb18d130f03f879898a 678 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 277 299 7.3E-14 T 14-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 LH59_06160 99adc0678c5cdeb18d130f03f879898a 678 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 431 453 7.3E-14 T 14-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 LH59_06160 99adc0678c5cdeb18d130f03f879898a 678 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 493 514 7.3E-14 T 14-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 LH59_06160 99adc0678c5cdeb18d130f03f879898a 678 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 65 89 7.3E-14 T 14-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 LH59_18600 cc29c092083683ee5102ab2bd76b99f1 409 Gene3D G3DSA:3.50.50.60 96 400 4.3E-53 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_18600 cc29c092083683ee5102ab2bd76b99f1 409 SUPERFAMILY SSF54373 271 363 3.01E-14 T 14-10-2018 LH59_18600 cc29c092083683ee5102ab2bd76b99f1 409 SUPERFAMILY SSF51905 1 404 2.59E-46 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_18600 cc29c092083683ee5102ab2bd76b99f1 409 Gene3D G3DSA:3.30.9.10 133 362 4.3E-53 T 14-10-2018 LH59_18600 cc29c092083683ee5102ab2bd76b99f1 409 Pfam PF01266 FAD dependent oxidoreductase 4 400 9.5E-69 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 LH59_18600 cc29c092083683ee5102ab2bd76b99f1 409 Gene3D G3DSA:3.50.50.60 4 53 1.5E-10 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_26910 d4ad0b9a2b497d92b555237e114a3724 112 SUPERFAMILY SSF46785 18 103 4.32E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_26910 d4ad0b9a2b497d92b555237e114a3724 112 SMART SM00418 22 100 6.0E-27 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LH59_26910 d4ad0b9a2b497d92b555237e114a3724 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 71 86 2.4E-13 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LH59_26910 d4ad0b9a2b497d92b555237e114a3724 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 56 71 2.4E-13 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LH59_26910 d4ad0b9a2b497d92b555237e114a3724 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 24 39 2.4E-13 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LH59_26910 d4ad0b9a2b497d92b555237e114a3724 112 Pfam PF01022 Bacterial regulatory protein, arsR family 30 74 2.1E-12 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LH59_26910 d4ad0b9a2b497d92b555237e114a3724 112 Gene3D G3DSA:1.10.10.10 10 108 7.9E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_06635 b47eebe7d1947c7bd5acdb1c7385fa67 497 Pfam PF00171 Aldehyde dehydrogenase family 18 479 7.8E-136 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 LH59_06635 b47eebe7d1947c7bd5acdb1c7385fa67 497 Gene3D G3DSA:3.40.309.10 252 452 3.1E-144 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 LH59_06635 b47eebe7d1947c7bd5acdb1c7385fa67 497 Gene3D G3DSA:3.40.605.10 26 460 3.1E-144 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 LH59_06635 b47eebe7d1947c7bd5acdb1c7385fa67 497 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 8 483 1.3E-211 T 14-10-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00640+1.2.1.27|MetaCyc: PWY-5642|Reactome: R-HSA-70895 LH59_06635 b47eebe7d1947c7bd5acdb1c7385fa67 497 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 277 288 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 LH59_06635 b47eebe7d1947c7bd5acdb1c7385fa67 497 SUPERFAMILY SSF53720 4 483 1.7E-143 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 LH59_02120 edcfd6d6899cb98673b6046b014b6355 546 SUPERFAMILY SSF53850 31 528 3.98E-121 T 14-10-2018 LH59_02120 edcfd6d6899cb98673b6046b014b6355 546 Gene3D G3DSA:3.40.190.10 40 296 3.4E-121 T 14-10-2018 LH59_02120 edcfd6d6899cb98673b6046b014b6355 546 Gene3D G3DSA:3.10.105.10 297 525 3.4E-121 T 14-10-2018 LH59_02120 edcfd6d6899cb98673b6046b014b6355 546 Gene3D G3DSA:3.90.76.10 66 186 3.4E-121 T 14-10-2018 LH59_02120 edcfd6d6899cb98673b6046b014b6355 546 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 76 460 5.8E-83 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain LH59_02120 edcfd6d6899cb98673b6046b014b6355 546 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 81 102 - T 14-10-2018 IPR023765 Solute-binding protein family 5, conserved site LH59_02120 edcfd6d6899cb98673b6046b014b6355 546 PIRSF PIRSF002741 1 537 2.0E-85 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 LH59_07575 f5d642e69036ae48ad5ccc2e9bee9de1 447 Gene3D G3DSA:3.30.565.10 292 441 8.8E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_07575 f5d642e69036ae48ad5ccc2e9bee9de1 447 Gene3D G3DSA:1.10.287.130 175 290 5.7E-20 T 14-10-2018 LH59_07575 f5d642e69036ae48ad5ccc2e9bee9de1 447 SMART SM00388 224 289 9.4E-12 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_07575 f5d642e69036ae48ad5ccc2e9bee9de1 447 SUPERFAMILY SSF55874 278 437 2.23E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_07575 f5d642e69036ae48ad5ccc2e9bee9de1 447 Pfam PF08521 Two-component sensor kinase N-terminal 22 145 2.6E-10 T 14-10-2018 IPR013727 Two-component sensor kinase, N-terminal LH59_07575 f5d642e69036ae48ad5ccc2e9bee9de1 447 Pfam PF00512 His Kinase A (phospho-acceptor) domain 225 288 2.0E-10 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_07575 f5d642e69036ae48ad5ccc2e9bee9de1 447 SUPERFAMILY SSF47384 207 288 1.16E-14 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 LH59_07575 f5d642e69036ae48ad5ccc2e9bee9de1 447 SMART SM00387 334 444 2.3E-31 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_07575 f5d642e69036ae48ad5ccc2e9bee9de1 447 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 337 433 6.2E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_07575 f5d642e69036ae48ad5ccc2e9bee9de1 447 PRINTS PR00344 Bacterial sensor protein C-terminal signature 371 385 9.8E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_07575 f5d642e69036ae48ad5ccc2e9bee9de1 447 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 421 9.8E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_07575 f5d642e69036ae48ad5ccc2e9bee9de1 447 PRINTS PR00344 Bacterial sensor protein C-terminal signature 389 399 9.8E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_08585 94f60fc46e3c62535662acab870c9015 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 139 150 2.0E-27 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 LH59_08585 94f60fc46e3c62535662acab870c9015 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 57 76 2.0E-27 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 LH59_08585 94f60fc46e3c62535662acab870c9015 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 273 296 2.0E-27 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 LH59_08585 94f60fc46e3c62535662acab870c9015 313 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 261 270 2.0E-27 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 LH59_08585 94f60fc46e3c62535662acab870c9015 313 Gene3D G3DSA:3.40.50.1370 142 295 1.1E-112 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 LH59_08585 94f60fc46e3c62535662acab870c9015 313 Gene3D G3DSA:3.40.50.1370 13 305 1.1E-112 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 LH59_08585 94f60fc46e3c62535662acab870c9015 313 SUPERFAMILY SSF53671 11 308 4.84E-102 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 LH59_08585 94f60fc46e3c62535662acab870c9015 313 PRINTS PR00102 Ornithine carbamoyltransferase signature 128 142 5.0E-30 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 LH59_08585 94f60fc46e3c62535662acab870c9015 313 PRINTS PR00102 Ornithine carbamoyltransferase signature 287 298 5.0E-30 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 LH59_08585 94f60fc46e3c62535662acab870c9015 313 PRINTS PR00102 Ornithine carbamoyltransferase signature 225 235 5.0E-30 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 LH59_08585 94f60fc46e3c62535662acab870c9015 313 PRINTS PR00102 Ornithine carbamoyltransferase signature 55 69 5.0E-30 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 LH59_08585 94f60fc46e3c62535662acab870c9015 313 PRINTS PR00102 Ornithine carbamoyltransferase signature 88 101 5.0E-30 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 LH59_08585 94f60fc46e3c62535662acab870c9015 313 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 12 308 2.8E-113 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 LH59_08585 94f60fc46e3c62535662acab870c9015 313 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 11 309 78.243 T 14-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 LH59_08585 94f60fc46e3c62535662acab870c9015 313 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 159 306 2.4E-47 T 14-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 LH59_08585 94f60fc46e3c62535662acab870c9015 313 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 57 64 - T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 LH59_08585 94f60fc46e3c62535662acab870c9015 313 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 12 151 1.4E-50 T 14-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 LH59_16500 9583466d2174b5928c42e461b3b6b5c8 894 SUPERFAMILY SSF52172 693 813 2.7E-22 T 14-10-2018 IPR011006 CheY-like superfamily LH59_16500 9583466d2174b5928c42e461b3b6b5c8 894 Pfam PF00072 Response regulator receiver domain 696 804 3.1E-12 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_16500 9583466d2174b5928c42e461b3b6b5c8 894 Pfam PF07695 7TM diverse intracellular signalling 192 387 6.2E-16 T 14-10-2018 IPR011623 7TM-DISM receptor, extracellular domain, type 1 LH59_16500 9583466d2174b5928c42e461b3b6b5c8 894 SMART SM00387 552 668 5.3E-34 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_16500 9583466d2174b5928c42e461b3b6b5c8 894 PRINTS PR00344 Bacterial sensor protein C-terminal signature 595 609 8.2E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_16500 9583466d2174b5928c42e461b3b6b5c8 894 PRINTS PR00344 Bacterial sensor protein C-terminal signature 613 623 8.2E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_16500 9583466d2174b5928c42e461b3b6b5c8 894 PRINTS PR00344 Bacterial sensor protein C-terminal signature 628 646 8.2E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_16500 9583466d2174b5928c42e461b3b6b5c8 894 PRINTS PR00344 Bacterial sensor protein C-terminal signature 652 665 8.2E-16 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_16500 9583466d2174b5928c42e461b3b6b5c8 894 Gene3D G3DSA:3.40.50.2300 690 820 7.4E-20 T 14-10-2018 LH59_16500 9583466d2174b5928c42e461b3b6b5c8 894 SUPERFAMILY SSF55874 517 665 2.75E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_16500 9583466d2174b5928c42e461b3b6b5c8 894 Gene3D G3DSA:2.60.40.2380 47 187 1.0E-17 T 14-10-2018 LH59_16500 9583466d2174b5928c42e461b3b6b5c8 894 Gene3D G3DSA:3.30.565.10 505 673 6.4E-42 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_16500 9583466d2174b5928c42e461b3b6b5c8 894 SMART SM00388 443 506 1.1E-15 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_16500 9583466d2174b5928c42e461b3b6b5c8 894 Gene3D G3DSA:1.10.287.130 407 502 3.9E-19 T 14-10-2018 LH59_16500 9583466d2174b5928c42e461b3b6b5c8 894 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 553 667 3.2E-28 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_16500 9583466d2174b5928c42e461b3b6b5c8 894 Pfam PF07696 7TMR-DISM extracellular 2 51 178 1.9E-22 T 14-10-2018 IPR011622 7TM-DISM receptor, extracellular domain, type 2 LH59_16500 9583466d2174b5928c42e461b3b6b5c8 894 SUPERFAMILY SSF47384 429 501 1.67E-14 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 LH59_16500 9583466d2174b5928c42e461b3b6b5c8 894 Pfam PF00512 His Kinase A (phospho-acceptor) domain 444 501 1.2E-12 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_16500 9583466d2174b5928c42e461b3b6b5c8 894 SMART SM00448 694 806 4.6E-13 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_04430 037427b98ea1d6bfb6ebcf97a3ff496e 179 PIRSF PIRSF004682 1 179 2.0E-54 T 14-10-2018 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 LH59_04430 037427b98ea1d6bfb6ebcf97a3ff496e 179 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 3 145 3.1E-43 T 14-10-2018 IPR006543 Histidinol-phosphate phosphatase GO:0016791 LH59_04430 037427b98ea1d6bfb6ebcf97a3ff496e 179 Gene3D G3DSA:3.40.50.1000 1 179 3.5E-54 T 14-10-2018 IPR023214 HAD superfamily LH59_04430 037427b98ea1d6bfb6ebcf97a3ff496e 179 Pfam PF13242 HAD-hyrolase-like 99 169 1.4E-10 T 14-10-2018 LH59_04430 037427b98ea1d6bfb6ebcf97a3ff496e 179 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 2 144 1.0E-30 T 14-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 LH59_04430 037427b98ea1d6bfb6ebcf97a3ff496e 179 SUPERFAMILY SSF56784 2 176 1.11E-44 T 14-10-2018 IPR036412 HAD-like superfamily LH59_08685 fe3611dd1cf6796c789f44b729d6e9ef 241 Pfam PF01895 PhoU domain 21 106 6.1E-19 T 14-10-2018 IPR026022 PhoU domain LH59_08685 fe3611dd1cf6796c789f44b729d6e9ef 241 Pfam PF01895 PhoU domain 124 209 8.4E-18 T 14-10-2018 IPR026022 PhoU domain LH59_08685 fe3611dd1cf6796c789f44b729d6e9ef 241 Gene3D G3DSA:1.20.58.220 1 116 8.3E-34 T 14-10-2018 IPR038078 PhoU-like domain superfamily LH59_08685 fe3611dd1cf6796c789f44b729d6e9ef 241 SUPERFAMILY SSF109755 7 226 4.81E-67 T 14-10-2018 LH59_08685 fe3611dd1cf6796c789f44b729d6e9ef 241 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 7 217 2.4E-64 T 14-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 LH59_08685 fe3611dd1cf6796c789f44b729d6e9ef 241 PIRSF PIRSF003107 2 223 1.3E-64 T 14-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 LH59_08685 fe3611dd1cf6796c789f44b729d6e9ef 241 Gene3D G3DSA:1.20.58.220 117 233 1.9E-35 T 14-10-2018 IPR038078 PhoU-like domain superfamily LH59_01170 59628ba50e5d35325ac1df7a87115d57 296 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 11 292 18.893 T 14-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 LH59_01170 59628ba50e5d35325ac1df7a87115d57 296 Pfam PF01040 UbiA prenyltransferase family 27 275 1.0E-55 T 14-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 LH59_01170 59628ba50e5d35325ac1df7a87115d57 296 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 14 291 7.2E-91 T 14-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 LH59_01170 59628ba50e5d35325ac1df7a87115d57 296 Gene3D G3DSA:1.10.357.140 18 190 8.5E-14 T 14-10-2018 LH59_20485 08a9209e582ffdd4bb47da13864e8744 235 Gene3D G3DSA:1.20.120.530 82 222 2.0E-26 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_20485 08a9209e582ffdd4bb47da13864e8744 235 SMART SM00895 86 213 1.1E-12 T 14-10-2018 IPR011711 GntR, C-terminal LH59_20485 08a9209e582ffdd4bb47da13864e8744 235 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 76 1.6E-18 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_20485 08a9209e582ffdd4bb47da13864e8744 235 Gene3D G3DSA:1.10.10.10 11 77 7.5E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_20485 08a9209e582ffdd4bb47da13864e8744 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 1.3E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_20485 08a9209e582ffdd4bb47da13864e8744 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 1.3E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_20485 08a9209e582ffdd4bb47da13864e8744 235 SMART SM00345 18 76 3.1E-15 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_20485 08a9209e582ffdd4bb47da13864e8744 235 Pfam PF07729 FCD domain 87 211 6.4E-19 T 14-10-2018 IPR011711 GntR, C-terminal LH59_20485 08a9209e582ffdd4bb47da13864e8744 235 SUPERFAMILY SSF46785 10 80 1.08E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_20485 08a9209e582ffdd4bb47da13864e8744 235 SUPERFAMILY SSF48008 82 220 2.88E-25 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_01715 801a0e6f42d94e41fa8bf5861fe13e89 196 SUPERFAMILY SSF53706 37 196 6.81E-53 T 14-10-2018 LH59_01715 801a0e6f42d94e41fa8bf5861fe13e89 196 Pfam PF00384 Molybdopterin oxidoreductase 108 140 1.2E-5 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_01715 801a0e6f42d94e41fa8bf5861fe13e89 196 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 49 67 - T 14-10-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 LH59_01715 801a0e6f42d94e41fa8bf5861fe13e89 196 Gene3D G3DSA:2.20.25.90 38 109 2.8E-17 T 14-10-2018 LH59_01715 801a0e6f42d94e41fa8bf5861fe13e89 196 SMART SM00926 44 105 9.4E-23 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_01715 801a0e6f42d94e41fa8bf5861fe13e89 196 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 44 104 6.8E-19 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_01715 801a0e6f42d94e41fa8bf5861fe13e89 196 Gene3D G3DSA:3.40.50.740 110 196 1.2E-33 T 14-10-2018 LH59_20780 14d8ba59f2ed93397626699522c03d4a 321 Gene3D G3DSA:3.40.190.150 26 311 3.3E-109 T 14-10-2018 LH59_20780 14d8ba59f2ed93397626699522c03d4a 321 PIRSF PIRSF017082 2 321 1.8E-86 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_20780 14d8ba59f2ed93397626699522c03d4a 321 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 318 4.3E-81 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_20780 14d8ba59f2ed93397626699522c03d4a 321 SUPERFAMILY SSF53850 112 281 1.21E-15 T 14-10-2018 LH59_20780 14d8ba59f2ed93397626699522c03d4a 321 Gene3D G3DSA:3.40.190.10 123 246 3.3E-109 T 14-10-2018 LH59_13870 1b1d7ebe2d0166c8ae805e2e9f516f75 304 Gene3D G3DSA:3.40.190.290 91 293 5.8E-34 T 14-10-2018 LH59_13870 1b1d7ebe2d0166c8ae805e2e9f516f75 304 SUPERFAMILY SSF53850 91 288 1.96E-36 T 14-10-2018 LH59_13870 1b1d7ebe2d0166c8ae805e2e9f516f75 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.4E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_13870 1b1d7ebe2d0166c8ae805e2e9f516f75 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.4E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_13870 1b1d7ebe2d0166c8ae805e2e9f516f75 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.4E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_13870 1b1d7ebe2d0166c8ae805e2e9f516f75 304 SUPERFAMILY SSF46785 1 110 2.18E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_13870 1b1d7ebe2d0166c8ae805e2e9f516f75 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 2.6E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_13870 1b1d7ebe2d0166c8ae805e2e9f516f75 304 Gene3D G3DSA:1.10.10.10 1 90 7.8E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_13870 1b1d7ebe2d0166c8ae805e2e9f516f75 304 Pfam PF03466 LysR substrate binding domain 91 288 6.0E-38 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_07430 29ddc7cd2fe6353fb01080de47e34c47 431 SUPERFAMILY SSF102114 67 299 6.54E-13 T 14-10-2018 LH59_07430 29ddc7cd2fe6353fb01080de47e34c47 431 Gene3D G3DSA:3.80.30.30 130 300 6.4E-7 T 14-10-2018 LH59_07430 29ddc7cd2fe6353fb01080de47e34c47 431 Pfam PF04055 Radical SAM superfamily 89 267 5.8E-11 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 LH59_07430 29ddc7cd2fe6353fb01080de47e34c47 431 SMART SM00729 85 310 1.4E-4 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 LH59_16570 a7198f099c416d0a9dca4419d98bccda 305 Pfam PF03466 LysR substrate binding domain 87 300 1.1E-19 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_16570 a7198f099c416d0a9dca4419d98bccda 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 5.1E-12 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_16570 a7198f099c416d0a9dca4419d98bccda 305 SUPERFAMILY SSF46785 1 84 3.47E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_16570 a7198f099c416d0a9dca4419d98bccda 305 Gene3D G3DSA:3.40.190.10 170 278 1.6E-13 T 14-10-2018 LH59_16570 a7198f099c416d0a9dca4419d98bccda 305 SUPERFAMILY SSF53850 90 301 1.57E-20 T 14-10-2018 LH59_16570 a7198f099c416d0a9dca4419d98bccda 305 Gene3D G3DSA:3.40.190.10 93 282 1.6E-13 T 14-10-2018 LH59_16570 a7198f099c416d0a9dca4419d98bccda 305 Gene3D G3DSA:1.10.10.10 1 91 2.5E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_05895 436688c01f24a98de6d5d306f9c88ac2 133 SMART SM00448 1 114 1.1E-34 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_05895 436688c01f24a98de6d5d306f9c88ac2 133 Gene3D G3DSA:3.40.50.12740 1 131 7.6E-38 T 14-10-2018 LH59_05895 436688c01f24a98de6d5d306f9c88ac2 133 Pfam PF00072 Response regulator receiver domain 3 114 1.6E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_05895 436688c01f24a98de6d5d306f9c88ac2 133 SUPERFAMILY SSF52172 1 122 1.85E-35 T 14-10-2018 IPR011006 CheY-like superfamily LH59_11330 e08652bc6df8b9d7269fac7e719b3b81 568 SUPERFAMILY SSF58104 251 536 5.62E-78 T 14-10-2018 LH59_11330 e08652bc6df8b9d7269fac7e719b3b81 568 Pfam PF00672 HAMP domain 231 279 4.9E-9 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_11330 e08652bc6df8b9d7269fac7e719b3b81 568 SMART SM00283 284 531 3.0E-97 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 LH59_11330 e08652bc6df8b9d7269fac7e719b3b81 568 Gene3D G3DSA:1.10.287.950 231 533 1.2E-96 T 14-10-2018 LH59_11330 e08652bc6df8b9d7269fac7e719b3b81 568 Gene3D G3DSA:1.20.120.30 85 183 1.6E-6 T 14-10-2018 LH59_11330 e08652bc6df8b9d7269fac7e719b3b81 568 SUPERFAMILY SSF47170 32 179 1.03E-16 T 14-10-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain superfamily LH59_11330 e08652bc6df8b9d7269fac7e719b3b81 568 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 343 499 8.5E-56 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 LH59_11330 e08652bc6df8b9d7269fac7e719b3b81 568 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 459 488 1.1E-62 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_11330 e08652bc6df8b9d7269fac7e719b3b81 568 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 8 33 1.1E-62 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_11330 e08652bc6df8b9d7269fac7e719b3b81 568 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 305 334 1.1E-62 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_11330 e08652bc6df8b9d7269fac7e719b3b81 568 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 411 440 1.1E-62 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_11330 e08652bc6df8b9d7269fac7e719b3b81 568 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 382 409 1.1E-62 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_11330 e08652bc6df8b9d7269fac7e719b3b81 568 Pfam PF02203 Tar ligand binding domain homologue 4 178 1.8E-22 T 14-10-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 LH59_11330 e08652bc6df8b9d7269fac7e719b3b81 568 SMART SM00304 231 283 1.8E-12 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_22835 902f75c35aa8e9884c04a9dce3714a25 496 Gene3D G3DSA:3.30.450.20 10 142 1.4E-7 T 14-10-2018 LH59_22835 902f75c35aa8e9884c04a9dce3714a25 496 Gene3D G3DSA:3.30.450.20 143 264 1.3E-14 T 14-10-2018 LH59_22835 902f75c35aa8e9884c04a9dce3714a25 496 SUPERFAMILY SSF46894 411 482 1.84E-18 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LH59_22835 902f75c35aa8e9884c04a9dce3714a25 496 Gene3D G3DSA:3.30.450.20 265 372 1.7E-12 T 14-10-2018 LH59_22835 902f75c35aa8e9884c04a9dce3714a25 496 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 262 381 1.2E-11 T 14-10-2018 IPR000014 PAS domain LH59_22835 902f75c35aa8e9884c04a9dce3714a25 496 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 139 260 9.0E-10 T 14-10-2018 IPR000014 PAS domain LH59_22835 902f75c35aa8e9884c04a9dce3714a25 496 SUPERFAMILY SSF55785 252 372 7.15E-18 T 14-10-2018 IPR035965 PAS domain superfamily LH59_22835 902f75c35aa8e9884c04a9dce3714a25 496 Pfam PF13188 PAS domain 14 51 0.039 T 14-10-2018 IPR000014 PAS domain LH59_22835 902f75c35aa8e9884c04a9dce3714a25 496 SUPERFAMILY SSF55785 24 143 9.42E-6 T 14-10-2018 IPR035965 PAS domain superfamily LH59_22835 902f75c35aa8e9884c04a9dce3714a25 496 Pfam PF00196 Bacterial regulatory proteins, luxR family 421 476 3.4E-15 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_22835 902f75c35aa8e9884c04a9dce3714a25 496 SUPERFAMILY SSF55785 160 261 4.19E-13 T 14-10-2018 IPR035965 PAS domain superfamily LH59_22835 902f75c35aa8e9884c04a9dce3714a25 496 SMART SM00421 419 476 1.6E-19 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_22835 902f75c35aa8e9884c04a9dce3714a25 496 Pfam PF08448 PAS fold 150 254 3.5E-6 T 14-10-2018 IPR013656 PAS fold-4 LH59_22835 902f75c35aa8e9884c04a9dce3714a25 496 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 452 464 5.3E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_22835 902f75c35aa8e9884c04a9dce3714a25 496 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 422 436 5.3E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_22835 902f75c35aa8e9884c04a9dce3714a25 496 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 436 452 5.3E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_22835 902f75c35aa8e9884c04a9dce3714a25 496 Gene3D G3DSA:1.10.10.10 373 492 4.2E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_22835 902f75c35aa8e9884c04a9dce3714a25 496 SMART SM00086 334 374 0.0048 T 14-10-2018 IPR001610 PAC motif LH59_22835 902f75c35aa8e9884c04a9dce3714a25 496 Pfam PF13426 PAS domain 278 373 7.7E-8 T 14-10-2018 IPR000014 PAS domain LH59_22835 902f75c35aa8e9884c04a9dce3714a25 496 SMART SM00091 13 82 6.9 T 14-10-2018 IPR000014 PAS domain LH59_22835 902f75c35aa8e9884c04a9dce3714a25 496 SMART SM00091 265 331 0.16 T 14-10-2018 IPR000014 PAS domain LH59_22835 902f75c35aa8e9884c04a9dce3714a25 496 SMART SM00091 140 210 0.39 T 14-10-2018 IPR000014 PAS domain LH59_05235 ab2f70211ab4785930265a947a4f3117 231 SUPERFAMILY SSF52540 21 141 9.19E-19 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_05235 ab2f70211ab4785930265a947a4f3117 231 Gene3D G3DSA:3.40.50.300 18 142 2.7E-19 T 14-10-2018 LH59_05235 ab2f70211ab4785930265a947a4f3117 231 Pfam PF00271 Helicase conserved C-terminal domain 21 112 2.6E-6 T 14-10-2018 IPR001650 Helicase, C-terminal LH59_07120 acbcfa402b5b90070628c4206c34cb37 66 SUPERFAMILY SSF69047 1 65 8.63E-26 T 14-10-2018 IPR036629 YjbJ superfamily LH59_07120 acbcfa402b5b90070628c4206c34cb37 66 Pfam PF05532 CsbD-like 4 56 9.8E-21 T 14-10-2018 IPR008462 CsbD-like domain LH59_07120 acbcfa402b5b90070628c4206c34cb37 66 Gene3D G3DSA:1.10.1470.10 1 64 5.7E-31 T 14-10-2018 IPR036629 YjbJ superfamily LH59_07120 acbcfa402b5b90070628c4206c34cb37 66 PIRSF PIRSF039008 1 66 1.2E-31 T 14-10-2018 IPR026042 Stress response protein YjbJ LH59_06985 de54021ebbd1f82847e65cc3ec296faa 363 Pfam PF03969 AFG1-like ATPase 3 355 7.7E-129 T 14-10-2018 IPR005654 ATPase, AFG1-like GO:0005524 LH59_06985 de54021ebbd1f82847e65cc3ec296faa 363 Gene3D G3DSA:3.40.50.300 1 187 8.2E-21 T 14-10-2018 LH59_06985 de54021ebbd1f82847e65cc3ec296faa 363 SUPERFAMILY SSF52540 45 194 6.35E-15 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_02545 4a96ced1cc330f9cab390b2b18baf531 1257 Gene3D G3DSA:1.10.1240.10 668 760 1.7E-37 T 14-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LH59_02545 4a96ced1cc330f9cab390b2b18baf531 1257 Gene3D G3DSA:3.20.20.20 352 663 3.3E-125 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LH59_02545 4a96ced1cc330f9cab390b2b18baf531 1257 PIRSF PIRSF000381 14 1229 0.0 T 14-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LH59_02545 4a96ced1cc330f9cab390b2b18baf531 1257 Pfam PF00809 Pterin binding enzyme 371 609 3.7E-57 T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LH59_02545 4a96ced1cc330f9cab390b2b18baf531 1257 SUPERFAMILY SSF52242 772 927 1.83E-42 T 14-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 LH59_02545 4a96ced1cc330f9cab390b2b18baf531 1257 TIGRFAM TIGR02082 metH: methionine synthase 24 1226 0.0 T 14-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LH59_02545 4a96ced1cc330f9cab390b2b18baf531 1257 Pfam PF02574 Homocysteine S-methyltransferase 28 336 3.2E-77 T 14-10-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 LH59_02545 4a96ced1cc330f9cab390b2b18baf531 1257 Gene3D G3DSA:3.10.196.10 940 1257 7.2E-135 T 14-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LH59_02545 4a96ced1cc330f9cab390b2b18baf531 1257 SUPERFAMILY SSF56507 934 1256 6.8E-122 T 14-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LH59_02545 4a96ced1cc330f9cab390b2b18baf531 1257 Pfam PF02310 B12 binding domain 778 871 2.5E-18 T 14-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 LH59_02545 4a96ced1cc330f9cab390b2b18baf531 1257 Gene3D G3DSA:1.10.288.10 969 1127 7.2E-135 T 14-10-2018 LH59_02545 4a96ced1cc330f9cab390b2b18baf531 1257 SUPERFAMILY SSF82282 19 410 1.31E-114 T 14-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 LH59_02545 4a96ced1cc330f9cab390b2b18baf531 1257 Pfam PF02607 B12 binding domain 679 755 2.7E-25 T 14-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LH59_02545 4a96ced1cc330f9cab390b2b18baf531 1257 Gene3D G3DSA:3.40.50.280 773 928 4.2E-54 T 14-10-2018 LH59_02545 4a96ced1cc330f9cab390b2b18baf531 1257 Gene3D G3DSA:3.20.20.330 15 351 3.7E-122 T 14-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 LH59_02545 4a96ced1cc330f9cab390b2b18baf531 1257 SUPERFAMILY SSF51717 367 635 2.75E-88 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LH59_02545 4a96ced1cc330f9cab390b2b18baf531 1257 SMART SM01018 676 763 6.8E-42 T 14-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LH59_02545 4a96ced1cc330f9cab390b2b18baf531 1257 SUPERFAMILY SSF47644 671 762 3.27E-26 T 14-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LH59_02545 4a96ced1cc330f9cab390b2b18baf531 1257 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 970 1241 2.1E-116 T 14-10-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LH59_18480 04a9c7bf28f839478cac8e0f18673b75 497 SUPERFAMILY SSF103473 207 491 2.88E-29 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_18480 04a9c7bf28f839478cac8e0f18673b75 497 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 9 482 9.7E-80 T 14-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 LH59_18480 04a9c7bf28f839478cac8e0f18673b75 497 Gene3D G3DSA:1.20.1250.20 263 489 1.9E-21 T 14-10-2018 LH59_18480 04a9c7bf28f839478cac8e0f18673b75 497 Gene3D G3DSA:1.20.1720.10 9 218 3.2E-50 T 14-10-2018 LH59_18480 04a9c7bf28f839478cac8e0f18673b75 497 Pfam PF07690 Major Facilitator Superfamily 15 405 1.3E-49 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_18480 04a9c7bf28f839478cac8e0f18673b75 497 SUPERFAMILY SSF103473 4 190 3.92E-43 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_22740 da4b927f250fb610a17e25ac147914ad 626 Gene3D G3DSA:1.20.1640.10 457 610 3.6E-10 T 14-10-2018 LH59_22740 da4b927f250fb610a17e25ac147914ad 626 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 2 616 46.978 T 14-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 LH59_22740 da4b927f250fb610a17e25ac147914ad 626 Gene3D G3DSA:3.30.70.3400 233 439 1.3E-57 T 14-10-2018 LH59_22740 da4b927f250fb610a17e25ac147914ad 626 Pfam PF02355 Protein export membrane protein 435 597 4.0E-19 T 14-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial LH59_22740 da4b927f250fb610a17e25ac147914ad 626 Pfam PF13721 SecD export protein N-terminal TM region 1 112 2.8E-34 T 14-10-2018 IPR027398 SecD export protein N-terminal TM domain LH59_22740 da4b927f250fb610a17e25ac147914ad 626 SUPERFAMILY SSF82866 412 611 8.11E-41 T 14-10-2018 LH59_22740 da4b927f250fb610a17e25ac147914ad 626 Pfam PF07549 SecD/SecF GG Motif 131 152 4.7E-6 T 14-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site LH59_22740 da4b927f250fb610a17e25ac147914ad 626 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 361 595 1.4E-73 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial LH59_22740 da4b927f250fb610a17e25ac147914ad 626 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 135 601 5.9E-143 T 14-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 LH59_22740 da4b927f250fb610a17e25ac147914ad 626 Gene3D G3DSA:3.30.1360.200 292 433 1.3E-57 T 14-10-2018 LH59_17785 bfc1a96ad67d7aa7631f83f67ce186e5 390 Pfam PF13458 Periplasmic binding protein 24 375 5.6E-47 T 14-10-2018 IPR028081 Leucine-binding protein domain LH59_17785 bfc1a96ad67d7aa7631f83f67ce186e5 390 Gene3D G3DSA:3.40.50.2300 27 366 7.5E-107 T 14-10-2018 LH59_17785 bfc1a96ad67d7aa7631f83f67ce186e5 390 Gene3D G3DSA:3.40.50.2300 144 379 7.5E-107 T 14-10-2018 LH59_17785 bfc1a96ad67d7aa7631f83f67ce186e5 390 SUPERFAMILY SSF53822 24 382 2.17E-65 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_11685 e0dd92f1ed168b7e920bae0b058de4d0 781 Gene3D G3DSA:3.10.20.310 278 359 1.1E-16 T 14-10-2018 LH59_11685 e0dd92f1ed168b7e920bae0b058de4d0 781 Gene3D G3DSA:3.10.20.310 361 437 1.9E-27 T 14-10-2018 LH59_11685 e0dd92f1ed168b7e920bae0b058de4d0 781 TIGRFAM TIGR03303 OM_YaeT: outer membrane protein assembly complex, YaeT protein 37 781 1.9E-270 T 14-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 LH59_11685 e0dd92f1ed168b7e920bae0b058de4d0 781 Gene3D G3DSA:3.10.20.310 105 186 1.1E-14 T 14-10-2018 LH59_11685 e0dd92f1ed168b7e920bae0b058de4d0 781 PIRSF PIRSF006076 4 781 9.0E-251 T 14-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 LH59_11685 e0dd92f1ed168b7e920bae0b058de4d0 781 Pfam PF01103 Surface antigen 461 781 3.0E-68 T 14-10-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 LH59_11685 e0dd92f1ed168b7e920bae0b058de4d0 781 Gene3D G3DSA:2.40.160.50 438 781 7.3E-98 T 14-10-2018 LH59_11685 e0dd92f1ed168b7e920bae0b058de4d0 781 Gene3D G3DSA:3.10.20.310 188 277 9.3E-27 T 14-10-2018 LH59_11685 e0dd92f1ed168b7e920bae0b058de4d0 781 Hamap MF_01430 Outer membrane protein assembly factor BamA [bamA]. 17 781 25.651 T 14-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 LH59_11685 e0dd92f1ed168b7e920bae0b058de4d0 781 Gene3D G3DSA:3.10.20.310 31 104 2.2E-21 T 14-10-2018 LH59_11685 e0dd92f1ed168b7e920bae0b058de4d0 781 Pfam PF07244 Surface antigen variable number repeat 279 356 3.3E-12 T 14-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 LH59_11685 e0dd92f1ed168b7e920bae0b058de4d0 781 Pfam PF07244 Surface antigen variable number repeat 360 434 9.3E-15 T 14-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 LH59_11685 e0dd92f1ed168b7e920bae0b058de4d0 781 Pfam PF07244 Surface antigen variable number repeat 105 185 4.2E-10 T 14-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 LH59_11685 e0dd92f1ed168b7e920bae0b058de4d0 781 Pfam PF07244 Surface antigen variable number repeat 189 276 5.8E-19 T 14-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 LH59_11685 e0dd92f1ed168b7e920bae0b058de4d0 781 Pfam PF07244 Surface antigen variable number repeat 38 103 2.3E-6 T 14-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 LH59_06270 15b8a8e438b8a069c09023c791390e66 188 Pfam PF04279 Intracellular septation protein A 3 178 6.7E-64 T 14-10-2018 IPR006008 Intracellular septation protein A GO:0016021 LH59_06270 15b8a8e438b8a069c09023c791390e66 188 Hamap MF_00189 Probable intracellular septation protein A [yciB]. 2 179 18.201 T 14-10-2018 IPR006008 Intracellular septation protein A GO:0016021 LH59_06270 15b8a8e438b8a069c09023c791390e66 188 TIGRFAM TIGR00997 ispZ: intracellular septation protein A 3 179 2.3E-52 T 14-10-2018 IPR006008 Intracellular septation protein A GO:0016021 LH59_16345 fd2545a95251b0d54f2b930cba3a141b 287 Pfam PF00800 Prephenate dehydratase 27 203 1.8E-35 T 14-10-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 LH59_16345 fd2545a95251b0d54f2b930cba3a141b 287 PIRSF PIRSF001500 8 287 6.9E-35 T 14-10-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 LH59_16345 fd2545a95251b0d54f2b930cba3a141b 287 Gene3D G3DSA:3.40.190.10 105 192 1.0E-30 T 14-10-2018 LH59_16345 fd2545a95251b0d54f2b930cba3a141b 287 Gene3D G3DSA:3.40.190.10 29 200 1.0E-30 T 14-10-2018 LH59_16345 fd2545a95251b0d54f2b930cba3a141b 287 SUPERFAMILY SSF53850 26 210 1.01E-31 T 14-10-2018 LH59_16345 fd2545a95251b0d54f2b930cba3a141b 287 Gene3D G3DSA:3.30.70.260 203 287 6.3E-7 T 14-10-2018 LH59_26585 b143604d2245b1b11fe671def76a866d 581 Gene3D G3DSA:1.20.1560.10 7 347 5.0E-48 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 LH59_26585 b143604d2245b1b11fe671def76a866d 581 Pfam PF00005 ABC transporter 383 531 5.7E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_26585 b143604d2245b1b11fe671def76a866d 581 SMART SM00382 392 577 5.1E-18 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_26585 b143604d2245b1b11fe671def76a866d 581 SUPERFAMILY SSF52540 366 578 1.43E-55 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_26585 b143604d2245b1b11fe671def76a866d 581 ProSitePatterns PS00211 ABC transporters family signature. 503 517 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_26585 b143604d2245b1b11fe671def76a866d 581 Gene3D G3DSA:3.40.50.300 363 581 1.9E-66 T 14-10-2018 LH59_26585 b143604d2245b1b11fe671def76a866d 581 Pfam PF00664 ABC transporter transmembrane region 40 284 6.5E-31 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 LH59_26585 b143604d2245b1b11fe671def76a866d 581 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 35 572 1.7E-184 T 14-10-2018 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 LH59_26585 b143604d2245b1b11fe671def76a866d 581 SUPERFAMILY SSF90123 22 351 6.41E-50 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 LH59_23295 54d7d1e8122206a70b81fa2eee22e9ba 429 Pfam PF05231 MASE1 14 293 1.1E-29 T 14-10-2018 IPR007895 MASE1 LH59_23295 54d7d1e8122206a70b81fa2eee22e9ba 429 Pfam PF08447 PAS fold 341 416 1.8E-6 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 LH59_23295 54d7d1e8122206a70b81fa2eee22e9ba 429 SUPERFAMILY SSF55785 341 418 2.3E-5 T 14-10-2018 IPR035965 PAS domain superfamily LH59_23295 54d7d1e8122206a70b81fa2eee22e9ba 429 Gene3D G3DSA:3.30.450.20 300 419 1.7E-11 T 14-10-2018 LH59_01615 e86c2d35a96d4f08db89452af0795f0f 404 Gene3D G3DSA:1.20.140.10 229 400 1.4E-55 T 14-10-2018 LH59_01615 e86c2d35a96d4f08db89452af0795f0f 404 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 27 127 4.0E-11 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 LH59_01615 e86c2d35a96d4f08db89452af0795f0f 404 PIRSF PIRSF016578 12 397 1.3E-34 T 14-10-2018 LH59_01615 e86c2d35a96d4f08db89452af0795f0f 404 Gene3D G3DSA:2.40.110.10 130 228 1.1E-30 T 14-10-2018 LH59_01615 e86c2d35a96d4f08db89452af0795f0f 404 Gene3D G3DSA:1.10.540.10 21 129 9.3E-24 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 LH59_01615 e86c2d35a96d4f08db89452af0795f0f 404 SUPERFAMILY SSF56645 26 228 1.96E-48 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 LH59_01615 e86c2d35a96d4f08db89452af0795f0f 404 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 139 220 3.4E-9 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 LH59_01615 e86c2d35a96d4f08db89452af0795f0f 404 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 246 379 1.7E-20 T 14-10-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain LH59_01615 e86c2d35a96d4f08db89452af0795f0f 404 TIGRFAM TIGR04022 sulfur_SfnB: sulfur acquisition oxidoreductase, SfnB family 14 402 5.4E-181 T 14-10-2018 IPR023922 Sulphate-starvation-induced SfnB LH59_01615 e86c2d35a96d4f08db89452af0795f0f 404 SUPERFAMILY SSF47203 242 396 5.48E-23 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 LH59_27060 492936a9451b68c2a1d1ff1f43f0dcdc 472 Gene3D G3DSA:3.40.50.1480 12 472 7.9E-239 T 14-10-2018 LH59_27060 492936a9451b68c2a1d1ff1f43f0dcdc 472 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 254 270 - T 14-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 LH59_27060 492936a9451b68c2a1d1ff1f43f0dcdc 472 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 83 97 - T 14-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 LH59_27060 492936a9451b68c2a1d1ff1f43f0dcdc 472 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 12 464 1.2E-184 T 14-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 LH59_27060 492936a9451b68c2a1d1ff1f43f0dcdc 472 SUPERFAMILY SSF52283 9 472 4.08E-111 T 14-10-2018 LH59_27060 492936a9451b68c2a1d1ff1f43f0dcdc 472 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 11 471 1.6E-144 T 14-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 LH59_27060 492936a9451b68c2a1d1ff1f43f0dcdc 472 PIRSF PIRSF001109 1 472 5.2E-188 T 14-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 LH59_27060 492936a9451b68c2a1d1ff1f43f0dcdc 472 SUPERFAMILY SSF51735 232 391 6.53E-79 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_27060 492936a9451b68c2a1d1ff1f43f0dcdc 472 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 232 391 6.5E-81 T 14-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 LH59_27060 492936a9451b68c2a1d1ff1f43f0dcdc 472 SMART SM00997 232 391 1.6E-113 T 14-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 LH59_27060 492936a9451b68c2a1d1ff1f43f0dcdc 472 SMART SM00996 11 471 0.0 T 14-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 LH59_27060 492936a9451b68c2a1d1ff1f43f0dcdc 472 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 7 464 48.408 T 14-10-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508|Reactome: R-HSA-5578997 LH59_27060 492936a9451b68c2a1d1ff1f43f0dcdc 472 Gene3D G3DSA:3.40.50.720 234 391 7.9E-239 T 14-10-2018 LH59_05485 a459763d2bfe714b33c5e08fd8e58893 493 Gene3D G3DSA:3.30.1490.130 283 339 1.4E-169 T 14-10-2018 IPR023100 D-aminoacylase, insert domain superfamily GO:0016811 LH59_05485 a459763d2bfe714b33c5e08fd8e58893 493 SUPERFAMILY SSF51556 56 414 4.93E-80 T 14-10-2018 IPR032466 Metal-dependent hydrolase LH59_05485 a459763d2bfe714b33c5e08fd8e58893 493 Gene3D G3DSA:3.20.20.140 55 414 1.4E-169 T 14-10-2018 LH59_05485 a459763d2bfe714b33c5e08fd8e58893 493 SUPERFAMILY SSF51338 1 471 5.01E-18 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 LH59_05485 a459763d2bfe714b33c5e08fd8e58893 493 Gene3D G3DSA:2.30.40.10 2 428 1.4E-169 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 LH59_05485 a459763d2bfe714b33c5e08fd8e58893 493 Pfam PF07969 Amidohydrolase family 45 458 2.8E-44 T 14-10-2018 IPR013108 Amidohydrolase 3 LH59_09135 f386c0664afb2d64d6f05ca38d810dc9 243 SMART SM00382 26 213 1.2E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_09135 f386c0664afb2d64d6f05ca38d810dc9 243 Gene3D G3DSA:3.40.50.300 1 243 7.2E-76 T 14-10-2018 LH59_09135 f386c0664afb2d64d6f05ca38d810dc9 243 Pfam PF00005 ABC transporter 17 165 2.6E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_09135 f386c0664afb2d64d6f05ca38d810dc9 243 SUPERFAMILY SSF52540 1 235 2.23E-77 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_09135 f386c0664afb2d64d6f05ca38d810dc9 243 PIRSF PIRSF039085 1 241 1.7E-113 T 14-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 LH59_09135 f386c0664afb2d64d6f05ca38d810dc9 243 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_16810 e01396d889a4d884c74d7359ff7ed88f 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 71 1.1E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_16810 e01396d889a4d884c74d7359ff7ed88f 202 SUPERFAMILY SSF46689 13 87 2.26E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_16810 e01396d889a4d884c74d7359ff7ed88f 202 Gene3D G3DSA:1.10.357.10 10 202 3.2E-23 T 14-10-2018 LH59_16810 e01396d889a4d884c74d7359ff7ed88f 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 1.4E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_16810 e01396d889a4d884c74d7359ff7ed88f 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 1.4E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_24295 bd9c4af1d1abfc5c68179aaaffeafe3b 95 Gene3D G3DSA:2.30.33.40 1 95 1.4E-39 T 14-10-2018 IPR037124 GroES chaperonin superfamily GO:0005737|GO:0006457 LH59_24295 bd9c4af1d1abfc5c68179aaaffeafe3b 95 ProSitePatterns PS00681 Chaperonins cpn10 signature. 3 27 - T 14-10-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 LH59_24295 bd9c4af1d1abfc5c68179aaaffeafe3b 95 SMART SM00883 2 94 8.7E-55 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 LH59_24295 bd9c4af1d1abfc5c68179aaaffeafe3b 95 SUPERFAMILY SSF50129 1 94 1.55E-34 T 14-10-2018 IPR011032 GroES-like superfamily LH59_24295 bd9c4af1d1abfc5c68179aaaffeafe3b 95 PRINTS PR00297 10kDa chaperonin signature 60 72 4.4E-33 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 LH59_24295 bd9c4af1d1abfc5c68179aaaffeafe3b 95 PRINTS PR00297 10kDa chaperonin signature 81 94 4.4E-33 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 LH59_24295 bd9c4af1d1abfc5c68179aaaffeafe3b 95 PRINTS PR00297 10kDa chaperonin signature 3 18 4.4E-33 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 LH59_24295 bd9c4af1d1abfc5c68179aaaffeafe3b 95 PRINTS PR00297 10kDa chaperonin signature 25 46 4.4E-33 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 LH59_24295 bd9c4af1d1abfc5c68179aaaffeafe3b 95 Hamap MF_00580 10 kDa chaperonin [groS]. 2 95 26.88 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 LH59_24295 bd9c4af1d1abfc5c68179aaaffeafe3b 95 Pfam PF00166 Chaperonin 10 Kd subunit 3 94 1.1E-35 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 LH59_26790 892dc2a48d6980cef98cac7884709048 262 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 2 258 1.6E-77 T 14-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 LH59_26790 892dc2a48d6980cef98cac7884709048 262 SUPERFAMILY SSF56219 2 259 2.75E-75 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily LH59_26790 892dc2a48d6980cef98cac7884709048 262 Gene3D G3DSA:3.60.10.10 1 260 2.9E-82 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily LH59_26790 892dc2a48d6980cef98cac7884709048 262 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 29 38 - T 14-10-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 LH59_26790 892dc2a48d6980cef98cac7884709048 262 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 7 251 5.6E-19 T 14-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase LH59_26790 892dc2a48d6980cef98cac7884709048 262 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 2 256 2.3E-73 T 14-10-2018 LH59_04600 ed9d6e0fd45fd6a67fab856ed02546b6 772 Pfam PF00593 TonB dependent receptor 169 769 3.3E-33 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_04600 ed9d6e0fd45fd6a67fab856ed02546b6 772 SUPERFAMILY SSF56935 9 772 1.37E-65 T 14-10-2018 LH59_04600 ed9d6e0fd45fd6a67fab856ed02546b6 772 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 755 772 - T 14-10-2018 IPR010917 TonB-dependent receptor, conserved site LH59_04600 ed9d6e0fd45fd6a67fab856ed02546b6 772 Gene3D G3DSA:2.170.130.10 16 154 1.1E-13 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily LH59_04600 ed9d6e0fd45fd6a67fab856ed02546b6 772 Gene3D G3DSA:2.40.170.20 158 772 1.3E-77 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_04600 ed9d6e0fd45fd6a67fab856ed02546b6 772 Pfam PF07715 TonB-dependent Receptor Plug Domain 19 127 2.5E-9 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_14875 2af738c9e231435308294a99226e416f 543 Pfam PF00005 ABC transporter 293 443 2.0E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_14875 2af738c9e231435308294a99226e416f 543 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 495 521 0.0013 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_14875 2af738c9e231435308294a99226e416f 543 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 267 8.7E-7 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_14875 2af738c9e231435308294a99226e416f 543 Gene3D G3DSA:3.40.50.300 1 272 1.3E-85 T 14-10-2018 LH59_14875 2af738c9e231435308294a99226e416f 543 Gene3D G3DSA:3.40.50.300 273 543 1.2E-84 T 14-10-2018 LH59_14875 2af738c9e231435308294a99226e416f 543 SMART SM00382 31 231 1.6E-19 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_14875 2af738c9e231435308294a99226e416f 543 SMART SM00382 302 501 9.1E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_14875 2af738c9e231435308294a99226e416f 543 SUPERFAMILY SSF52540 5 253 2.11E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_14875 2af738c9e231435308294a99226e416f 543 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_14875 2af738c9e231435308294a99226e416f 543 SUPERFAMILY SSF52540 274 515 1.01E-73 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_14875 2af738c9e231435308294a99226e416f 543 Pfam PF00005 ABC transporter 23 181 8.3E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_14875 2af738c9e231435308294a99226e416f 543 ProSitePatterns PS00211 ABC transporters family signature. 416 430 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_26280 62ed974859776b76c888ce9353f0b84a 252 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 84 114 - T 14-10-2018 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 LH59_26280 62ed974859776b76c888ce9353f0b84a 252 Gene3D G3DSA:3.40.50.1820 29 243 1.2E-48 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_26280 62ed974859776b76c888ce9353f0b84a 252 SUPERFAMILY SSF53474 9 238 5.99E-39 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_26280 62ed974859776b76c888ce9353f0b84a 252 Pfam PF00326 Prolyl oligopeptidase family 43 239 1.5E-10 T 14-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 LH59_21850 994035f59725b92e2fa14f0217a8ab3a 262 SUPERFAMILY SSF54862 15 100 2.14E-24 T 14-10-2018 LH59_21850 994035f59725b92e2fa14f0217a8ab3a 262 Pfam PF05187 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S 11 100 2.6E-40 T 14-10-2018 LH59_21850 994035f59725b92e2fa14f0217a8ab3a 262 SUPERFAMILY SSF51905 180 239 7.0E-6 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_21850 994035f59725b92e2fa14f0217a8ab3a 262 Gene3D G3DSA:3.30.70.20 16 100 3.3E-32 T 14-10-2018 LH59_21850 994035f59725b92e2fa14f0217a8ab3a 262 SUPERFAMILY SSF51395 109 207 3.7E-20 T 14-10-2018 LH59_21850 994035f59725b92e2fa14f0217a8ab3a 262 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 112 171 1.1E-7 T 14-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 LH59_21850 994035f59725b92e2fa14f0217a8ab3a 262 Gene3D G3DSA:3.20.20.70 101 187 1.5E-5 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_21910 aa1b33444263f26dddcdb9665e297a8a 267 Pfam PF13444 Acetyltransferase (GNAT) domain 42 143 2.7E-32 T 14-10-2018 LH59_21910 aa1b33444263f26dddcdb9665e297a8a 267 SUPERFAMILY SSF55729 25 232 4.99E-43 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_21910 aa1b33444263f26dddcdb9665e297a8a 267 Gene3D G3DSA:3.40.630.30 28 169 4.8E-27 T 14-10-2018 LH59_05965 06c1ea2a3751d125c5e2b2fdb67799c0 551 Pfam PF00005 ABC transporter 298 448 3.6E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_05965 06c1ea2a3751d125c5e2b2fdb67799c0 551 SUPERFAMILY SSF52540 273 520 5.43E-68 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_05965 06c1ea2a3751d125c5e2b2fdb67799c0 551 SMART SM00382 31 233 3.3E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_05965 06c1ea2a3751d125c5e2b2fdb67799c0 551 SMART SM00382 307 498 1.4E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_05965 06c1ea2a3751d125c5e2b2fdb67799c0 551 ProSitePatterns PS00211 ABC transporters family signature. 421 435 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_05965 06c1ea2a3751d125c5e2b2fdb67799c0 551 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 267 1.7E-6 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_05965 06c1ea2a3751d125c5e2b2fdb67799c0 551 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 500 532 1.5E-4 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_05965 06c1ea2a3751d125c5e2b2fdb67799c0 551 SUPERFAMILY SSF52540 4 254 5.69E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_05965 06c1ea2a3751d125c5e2b2fdb67799c0 551 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_05965 06c1ea2a3751d125c5e2b2fdb67799c0 551 Pfam PF00005 ABC transporter 23 181 2.4E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_05965 06c1ea2a3751d125c5e2b2fdb67799c0 551 Gene3D G3DSA:3.40.50.300 1 270 8.8E-83 T 14-10-2018 LH59_05965 06c1ea2a3751d125c5e2b2fdb67799c0 551 Gene3D G3DSA:3.40.50.300 271 549 5.5E-87 T 14-10-2018 LH59_02475 e6f0613f2cc9091286d9e695a7d9d292 435 SUPERFAMILY SSF47384 190 271 1.22E-20 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 LH59_02475 e6f0613f2cc9091286d9e695a7d9d292 435 SUPERFAMILY SSF55785 85 195 3.62E-6 T 14-10-2018 IPR035965 PAS domain superfamily LH59_02475 e6f0613f2cc9091286d9e695a7d9d292 435 SMART SM00387 315 428 8.9E-34 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_02475 e6f0613f2cc9091286d9e695a7d9d292 435 TIGRFAM TIGR02966 phoR_proteo: phosphate regulon sensor kinase PhoR 94 424 5.9E-124 T 14-10-2018 IPR014310 Signal transduction histidine kinase, phosphate regulon sensor PhoR GO:0000155|GO:0000160|GO:0004673|GO:0016021 LH59_02475 e6f0613f2cc9091286d9e695a7d9d292 435 Gene3D G3DSA:1.10.287.130 196 272 1.1E-24 T 14-10-2018 LH59_02475 e6f0613f2cc9091286d9e695a7d9d292 435 Pfam PF00512 His Kinase A (phospho-acceptor) domain 204 271 4.1E-23 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_02475 e6f0613f2cc9091286d9e695a7d9d292 435 Gene3D G3DSA:3.30.565.10 280 430 5.6E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_02475 e6f0613f2cc9091286d9e695a7d9d292 435 SUPERFAMILY SSF55874 262 425 5.89E-39 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_02475 e6f0613f2cc9091286d9e695a7d9d292 435 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 316 426 4.4E-21 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_02475 e6f0613f2cc9091286d9e695a7d9d292 435 PRINTS PR00344 Bacterial sensor protein C-terminal signature 353 367 5.8E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_02475 e6f0613f2cc9091286d9e695a7d9d292 435 PRINTS PR00344 Bacterial sensor protein C-terminal signature 388 406 5.8E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_02475 e6f0613f2cc9091286d9e695a7d9d292 435 PRINTS PR00344 Bacterial sensor protein C-terminal signature 412 425 5.8E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_02475 e6f0613f2cc9091286d9e695a7d9d292 435 PRINTS PR00344 Bacterial sensor protein C-terminal signature 371 381 5.8E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_02475 e6f0613f2cc9091286d9e695a7d9d292 435 SMART SM00388 203 272 1.3E-24 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_02475 e6f0613f2cc9091286d9e695a7d9d292 435 Pfam PF11808 Domain of unknown function (DUF3329) 3 83 3.7E-13 T 14-10-2018 IPR021766 Phosphate regulon sensor protein PhoR GO:0000155|GO:0000160|GO:0004721 LH59_22285 04e36edac15a03ae604aecdf790e8d19 518 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 380 515 2.6E-23 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 LH59_22285 04e36edac15a03ae604aecdf790e8d19 518 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 169 5.3E-34 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 LH59_22285 04e36edac15a03ae604aecdf790e8d19 518 SUPERFAMILY SSF52518 1 172 3.98E-39 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold LH59_22285 04e36edac15a03ae604aecdf790e8d19 518 Gene3D G3DSA:3.40.50.970 1 176 4.4E-41 T 14-10-2018 LH59_22285 04e36edac15a03ae604aecdf790e8d19 518 Gene3D G3DSA:3.40.50.970 337 518 3.8E-39 T 14-10-2018 LH59_22285 04e36edac15a03ae604aecdf790e8d19 518 SUPERFAMILY SSF52518 342 518 1.18E-36 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold LH59_06005 499cd1d749b14d6d3fb05c0d44ff865f 207 SUPERFAMILY SSF46689 6 85 7.18E-19 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_06005 499cd1d749b14d6d3fb05c0d44ff865f 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 8.2E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_06005 499cd1d749b14d6d3fb05c0d44ff865f 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 8.2E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_06005 499cd1d749b14d6d3fb05c0d44ff865f 207 SUPERFAMILY SSF48498 87 198 7.12E-11 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily LH59_06005 499cd1d749b14d6d3fb05c0d44ff865f 207 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 107 198 7.0E-8 T 14-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal LH59_06005 499cd1d749b14d6d3fb05c0d44ff865f 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 64 1.5E-12 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_06005 499cd1d749b14d6d3fb05c0d44ff865f 207 Gene3D G3DSA:1.10.357.10 3 201 4.0E-35 T 14-10-2018 LH59_02220 810735f77060183cc00f698405451641 334 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 7.1E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_02220 810735f77060183cc00f698405451641 334 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 64 75 7.1E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_02220 810735f77060183cc00f698405451641 334 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 54 64 7.1E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_02220 810735f77060183cc00f698405451641 334 SUPERFAMILY SSF46785 31 112 1.31E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_02220 810735f77060183cc00f698405451641 334 Gene3D G3DSA:3.40.190.10 117 315 1.6E-59 T 14-10-2018 LH59_02220 810735f77060183cc00f698405451641 334 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 33 87 1.8E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_02220 810735f77060183cc00f698405451641 334 Gene3D G3DSA:1.10.10.10 28 113 1.1E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_02220 810735f77060183cc00f698405451641 334 SUPERFAMILY SSF53850 114 321 3.26E-43 T 14-10-2018 LH59_02220 810735f77060183cc00f698405451641 334 Gene3D G3DSA:3.40.190.10 188 289 1.6E-59 T 14-10-2018 LH59_02220 810735f77060183cc00f698405451641 334 Pfam PF03466 LysR substrate binding domain 113 317 7.9E-39 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_09400 de3bddf81babc9b2dafe3ceb20d08bba 478 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 75 98 5.1E-47 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 LH59_09400 de3bddf81babc9b2dafe3ceb20d08bba 478 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 344 365 5.1E-47 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 LH59_09400 de3bddf81babc9b2dafe3ceb20d08bba 478 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 377 401 5.1E-47 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 LH59_09400 de3bddf81babc9b2dafe3ceb20d08bba 478 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 442 457 5.1E-47 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 LH59_09400 de3bddf81babc9b2dafe3ceb20d08bba 478 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 401 424 5.1E-47 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 LH59_09400 de3bddf81babc9b2dafe3ceb20d08bba 478 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 117 137 5.1E-47 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 LH59_09400 de3bddf81babc9b2dafe3ceb20d08bba 478 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 457 477 5.1E-47 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 LH59_09400 de3bddf81babc9b2dafe3ceb20d08bba 478 TIGRFAM TIGR01843 type_I_hlyD: type I secretion membrane fusion protein, HlyD family 65 478 2.2E-124 T 14-10-2018 IPR010129 Type I secretion membrane fusion protein, HlyD family GO:0015031|GO:0016021 LH59_09400 de3bddf81babc9b2dafe3ceb20d08bba 478 Gene3D G3DSA:2.40.50.100 104 138 5.7E-10 T 14-10-2018 LH59_09400 de3bddf81babc9b2dafe3ceb20d08bba 478 Gene3D G3DSA:1.10.287.470 139 165 5.7E-10 T 14-10-2018 LH59_09400 de3bddf81babc9b2dafe3ceb20d08bba 478 Gene3D G3DSA:1.10.287.470 204 309 8.0E-7 T 14-10-2018 LH59_09400 de3bddf81babc9b2dafe3ceb20d08bba 478 ProSitePatterns PS00543 HlyD family secretion proteins signature. 442 464 - T 14-10-2018 IPR006144 Secretion protein HlyD, conserved site GO:0008565|GO:0009306|GO:0016020 LH59_09400 de3bddf81babc9b2dafe3ceb20d08bba 478 Pfam PF13437 HlyD family secretion protein 332 444 7.9E-18 T 14-10-2018 LH59_09400 de3bddf81babc9b2dafe3ceb20d08bba 478 Gene3D G3DSA:2.40.30.170 93 103 5.7E-10 T 14-10-2018 LH59_09400 de3bddf81babc9b2dafe3ceb20d08bba 478 Pfam PF13533 Biotin-lipoyl like 105 144 5.3E-9 T 14-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain LH59_09400 de3bddf81babc9b2dafe3ceb20d08bba 478 SUPERFAMILY SSF111369 97 211 4.05E-6 T 14-10-2018 LH59_09400 de3bddf81babc9b2dafe3ceb20d08bba 478 Gene3D G3DSA:2.40.30.170 346 460 2.4E-10 T 14-10-2018 LH59_18880 c224dd8b2400e7d14616db38bec6a965 147 PIRSF PIRSF001263 1 147 1.2E-49 T 14-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 LH59_18880 c224dd8b2400e7d14616db38bec6a965 147 TIGRFAM TIGR00673 cynS: cyanase 6 147 9.5E-50 T 14-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 LH59_18880 c224dd8b2400e7d14616db38bec6a965 147 Hamap MF_00535 Cyanate hydratase [cynS]. 1 147 79.545 T 14-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 LH59_18880 c224dd8b2400e7d14616db38bec6a965 147 Gene3D G3DSA:3.30.1160.10 81 147 3.2E-34 T 14-10-2018 IPR036581 Cyanate lyase, C-terminal domain superfamily GO:0009439 KEGG: 00910+4.2.1.104 LH59_18880 c224dd8b2400e7d14616db38bec6a965 147 SUPERFAMILY SSF55234 80 147 6.02E-30 T 14-10-2018 IPR036581 Cyanate lyase, C-terminal domain superfamily GO:0009439 KEGG: 00910+4.2.1.104 LH59_18880 c224dd8b2400e7d14616db38bec6a965 147 Pfam PF02560 Cyanate lyase C-terminal domain 79 145 1.5E-35 T 14-10-2018 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00910+4.2.1.104 LH59_18880 c224dd8b2400e7d14616db38bec6a965 147 Gene3D G3DSA:1.10.260.40 1 80 3.7E-28 T 14-10-2018 LH59_18880 c224dd8b2400e7d14616db38bec6a965 147 PRINTS PR01693 Cyanase signature 14 29 1.1E-25 T 14-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 LH59_18880 c224dd8b2400e7d14616db38bec6a965 147 PRINTS PR01693 Cyanase signature 132 142 1.1E-25 T 14-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 LH59_18880 c224dd8b2400e7d14616db38bec6a965 147 PRINTS PR01693 Cyanase signature 101 117 1.1E-25 T 14-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 LH59_18880 c224dd8b2400e7d14616db38bec6a965 147 PRINTS PR01693 Cyanase signature 34 51 1.1E-25 T 14-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 LH59_18880 c224dd8b2400e7d14616db38bec6a965 147 PRINTS PR01693 Cyanase signature 83 97 1.1E-25 T 14-10-2018 IPR008076 Cyanate hydratase GO:0008824|GO:0009439 KEGG: 00910+4.2.1.104 LH59_18880 c224dd8b2400e7d14616db38bec6a965 147 SMART SM01116 75 147 4.4E-49 T 14-10-2018 IPR003712 Cyanate lyase, C-terminal GO:0009439 KEGG: 00910+4.2.1.104 LH59_18880 c224dd8b2400e7d14616db38bec6a965 147 SUPERFAMILY SSF47413 1 77 9.6E-21 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 LH59_05045 5d0ddc5d11c6350bd72aa3bdc6d5326e 389 SUPERFAMILY SSF51905 6 376 2.11E-28 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_05045 5d0ddc5d11c6350bd72aa3bdc6d5326e 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 2.2E-13 T 14-10-2018 LH59_05045 5d0ddc5d11c6350bd72aa3bdc6d5326e 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 276 291 2.2E-13 T 14-10-2018 LH59_05045 5d0ddc5d11c6350bd72aa3bdc6d5326e 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 291 307 2.2E-13 T 14-10-2018 LH59_05045 5d0ddc5d11c6350bd72aa3bdc6d5326e 389 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 7 384 2.4E-85 T 14-10-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 LH59_05045 5d0ddc5d11c6350bd72aa3bdc6d5326e 389 Pfam PF01494 FAD binding domain 156 313 9.5E-11 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 LH59_05045 5d0ddc5d11c6350bd72aa3bdc6d5326e 389 Gene3D G3DSA:3.50.50.60 7 330 1.9E-63 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_05045 5d0ddc5d11c6350bd72aa3bdc6d5326e 389 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 290 303 - T 14-10-2018 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 LH59_05045 5d0ddc5d11c6350bd72aa3bdc6d5326e 389 Gene3D G3DSA:3.30.9.50 84 265 1.9E-63 T 14-10-2018 LH59_24575 216f6ed6fbbf984bc0e4927a40622bd8 317 Gene3D G3DSA:3.60.15.10 11 236 1.5E-44 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like LH59_24575 216f6ed6fbbf984bc0e4927a40622bd8 317 SMART SM00849 33 220 3.2E-13 T 14-10-2018 IPR001279 Metallo-beta-lactamase LH59_24575 216f6ed6fbbf984bc0e4927a40622bd8 317 Pfam PF00753 Metallo-beta-lactamase superfamily 33 219 1.5E-10 T 14-10-2018 IPR001279 Metallo-beta-lactamase LH59_24575 216f6ed6fbbf984bc0e4927a40622bd8 317 SUPERFAMILY SSF56281 15 309 1.4E-57 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like LH59_23390 8cd50689b091098c5243d8c86b474417 264 Pfam PF02311 AraC-like ligand binding domain 24 143 5.7E-19 T 14-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 LH59_23390 8cd50689b091098c5243d8c86b474417 264 SMART SM00342 177 259 5.5E-25 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_23390 8cd50689b091098c5243d8c86b474417 264 SUPERFAMILY SSF51215 24 147 4.84E-11 T 14-10-2018 IPR037923 Transcription regulator HTH-like LH59_23390 8cd50689b091098c5243d8c86b474417 264 SUPERFAMILY SSF46689 213 258 6.72E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_23390 8cd50689b091098c5243d8c86b474417 264 Gene3D G3DSA:1.10.10.60 221 264 1.5E-9 T 14-10-2018 LH59_23390 8cd50689b091098c5243d8c86b474417 264 Pfam PF12833 Helix-turn-helix domain 183 258 2.5E-20 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_23390 8cd50689b091098c5243d8c86b474417 264 Gene3D G3DSA:1.10.10.60 159 220 2.2E-15 T 14-10-2018 LH59_23390 8cd50689b091098c5243d8c86b474417 264 SUPERFAMILY SSF46689 162 211 5.46E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_07605 cfdff41140e482a182e6e08d2b5b56a7 293 Gene3D G3DSA:1.10.10.10 1 85 6.2E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_07605 cfdff41140e482a182e6e08d2b5b56a7 293 Pfam PF03466 LysR substrate binding domain 83 285 5.9E-38 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_07605 cfdff41140e482a182e6e08d2b5b56a7 293 SUPERFAMILY SSF46785 2 105 9.58E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_07605 cfdff41140e482a182e6e08d2b5b56a7 293 Gene3D G3DSA:3.40.190.10 86 283 5.3E-58 T 14-10-2018 LH59_07605 cfdff41140e482a182e6e08d2b5b56a7 293 Gene3D G3DSA:3.40.190.10 157 256 5.3E-58 T 14-10-2018 LH59_07605 cfdff41140e482a182e6e08d2b5b56a7 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 1 56 4.4E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_07605 cfdff41140e482a182e6e08d2b5b56a7 293 SUPERFAMILY SSF53850 83 291 1.48E-43 T 14-10-2018 LH59_11240 72b1a210e6f931352ece3594e6f93a61 584 SUPERFAMILY SSF55874 410 569 8.29E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_11240 72b1a210e6f931352ece3594e6f93a61 584 Gene3D G3DSA:3.30.565.10 420 580 6.9E-36 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_11240 72b1a210e6f931352ece3594e6f93a61 584 Gene3D G3DSA:1.10.287.130 356 418 5.4E-18 T 14-10-2018 LH59_11240 72b1a210e6f931352ece3594e6f93a61 584 PRINTS PR00344 Bacterial sensor protein C-terminal signature 502 516 9.1E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_11240 72b1a210e6f931352ece3594e6f93a61 584 PRINTS PR00344 Bacterial sensor protein C-terminal signature 529 547 9.1E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_11240 72b1a210e6f931352ece3594e6f93a61 584 PRINTS PR00344 Bacterial sensor protein C-terminal signature 518 528 9.1E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_11240 72b1a210e6f931352ece3594e6f93a61 584 PRINTS PR00344 Bacterial sensor protein C-terminal signature 553 566 9.1E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_11240 72b1a210e6f931352ece3594e6f93a61 584 SMART SM00086 179 221 4.8E-4 T 14-10-2018 IPR001610 PAC motif LH59_11240 72b1a210e6f931352ece3594e6f93a61 584 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 106 228 1.5E-24 T 14-10-2018 IPR000014 PAS domain LH59_11240 72b1a210e6f931352ece3594e6f93a61 584 SMART SM00387 463 569 9.3E-29 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_11240 72b1a210e6f931352ece3594e6f93a61 584 Pfam PF00512 His Kinase A (phospho-acceptor) domain 352 418 4.8E-8 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_11240 72b1a210e6f931352ece3594e6f93a61 584 SUPERFAMILY SSF47384 339 418 1.08E-8 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 LH59_11240 72b1a210e6f931352ece3594e6f93a61 584 Pfam PF13188 PAS domain 233 283 0.011 T 14-10-2018 IPR000014 PAS domain LH59_11240 72b1a210e6f931352ece3594e6f93a61 584 SMART SM00091 233 304 49.0 T 14-10-2018 IPR000014 PAS domain LH59_11240 72b1a210e6f931352ece3594e6f93a61 584 SMART SM00091 105 172 1.1E-8 T 14-10-2018 IPR000014 PAS domain LH59_11240 72b1a210e6f931352ece3594e6f93a61 584 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 464 566 4.0E-16 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_11240 72b1a210e6f931352ece3594e6f93a61 584 Pfam PF08448 PAS fold 114 223 8.4E-16 T 14-10-2018 IPR013656 PAS fold-4 LH59_11240 72b1a210e6f931352ece3594e6f93a61 584 SUPERFAMILY SSF55785 218 327 8.9E-8 T 14-10-2018 IPR035965 PAS domain superfamily LH59_11240 72b1a210e6f931352ece3594e6f93a61 584 Gene3D G3DSA:3.30.450.20 101 236 3.8E-26 T 14-10-2018 LH59_11240 72b1a210e6f931352ece3594e6f93a61 584 SUPERFAMILY SSF55785 94 219 5.23E-24 T 14-10-2018 IPR035965 PAS domain superfamily LH59_11240 72b1a210e6f931352ece3594e6f93a61 584 SMART SM00388 351 421 3.9E-8 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_04230 a6db419567bd51ff3cbdc511f2401dc7 538 SUPERFAMILY SSF58104 234 520 1.01E-73 T 14-10-2018 LH59_04230 a6db419567bd51ff3cbdc511f2401dc7 538 Pfam PF00672 HAMP domain 214 262 6.1E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_04230 a6db419567bd51ff3cbdc511f2401dc7 538 SMART SM00283 267 514 8.8E-91 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 LH59_04230 a6db419567bd51ff3cbdc511f2401dc7 538 Gene3D G3DSA:1.10.287.950 214 516 1.1E-88 T 14-10-2018 LH59_04230 a6db419567bd51ff3cbdc511f2401dc7 538 SUPERFAMILY SSF47170 31 176 4.19E-18 T 14-10-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain superfamily LH59_04230 a6db419567bd51ff3cbdc511f2401dc7 538 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 288 317 6.6E-63 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_04230 a6db419567bd51ff3cbdc511f2401dc7 538 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 365 392 6.6E-63 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_04230 a6db419567bd51ff3cbdc511f2401dc7 538 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 5 30 6.6E-63 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_04230 a6db419567bd51ff3cbdc511f2401dc7 538 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 61 76 6.6E-63 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_04230 a6db419567bd51ff3cbdc511f2401dc7 538 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 394 423 6.6E-63 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_04230 a6db419567bd51ff3cbdc511f2401dc7 538 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 442 471 6.6E-63 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_04230 a6db419567bd51ff3cbdc511f2401dc7 538 Gene3D G3DSA:1.20.120.30 25 192 8.1E-10 T 14-10-2018 LH59_04230 a6db419567bd51ff3cbdc511f2401dc7 538 SMART SM00304 214 266 7.4E-12 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_04230 a6db419567bd51ff3cbdc511f2401dc7 538 Pfam PF02203 Tar ligand binding domain homologue 1 152 2.0E-21 T 14-10-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 LH59_04230 a6db419567bd51ff3cbdc511f2401dc7 538 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 327 482 6.5E-53 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 LH59_14575 eb16e72e667a97b30864c394fe1684e2 314 SUPERFAMILY SSF53850 92 301 5.97E-37 T 14-10-2018 LH59_14575 eb16e72e667a97b30864c394fe1684e2 314 SUPERFAMILY SSF46785 5 90 6.67E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_14575 eb16e72e667a97b30864c394fe1684e2 314 Pfam PF03466 LysR substrate binding domain 91 297 1.2E-35 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_14575 eb16e72e667a97b30864c394fe1684e2 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 66 2.2E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_14575 eb16e72e667a97b30864c394fe1684e2 314 Gene3D G3DSA:1.10.10.10 5 92 1.3E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_14575 eb16e72e667a97b30864c394fe1684e2 314 Gene3D G3DSA:3.40.190.290 95 296 1.2E-44 T 14-10-2018 LH59_05725 202b091248f102a319f12e7dec216261 248 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 10 240 2.4E-59 T 14-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_05725 202b091248f102a319f12e7dec216261 248 Pfam PF00121 Triosephosphate isomerase 10 245 3.7E-84 T 14-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_05725 202b091248f102a319f12e7dec216261 248 SUPERFAMILY SSF51351 5 246 1.44E-85 T 14-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_05725 202b091248f102a319f12e7dec216261 248 Gene3D G3DSA:3.20.20.70 1 248 7.3E-95 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_05725 202b091248f102a319f12e7dec216261 248 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 7 248 58.661 T 14-10-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_05725 202b091248f102a319f12e7dec216261 248 ProSitePatterns PS00171 Triosephosphate isomerase active site. 168 178 - T 14-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_07465 e0d46c84f25add711fdc36a100729016 181 SUPERFAMILY SSF53098 2 180 1.32E-49 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily LH59_07465 e0d46c84f25add711fdc36a100729016 181 Pfam PF00929 Exonuclease 9 170 1.1E-32 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III LH59_07465 e0d46c84f25add711fdc36a100729016 181 SMART SM00479 7 180 9.6E-27 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III LH59_07465 e0d46c84f25add711fdc36a100729016 181 Hamap MF_00045 Oligoribonuclease [orn]. 3 181 43.51 T 14-10-2018 IPR022894 Oligoribonuclease GO:0000175 LH59_07465 e0d46c84f25add711fdc36a100729016 181 Gene3D G3DSA:3.30.420.10 1 181 2.8E-73 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 LH59_02800 7db09bb17675e0699360f9dc00b377c5 1032 SUPERFAMILY SSF82693 138 324 4.34E-23 T 14-10-2018 LH59_02800 7db09bb17675e0699360f9dc00b377c5 1032 Gene3D G3DSA:1.20.1640.10 10 503 9.9E-300 T 14-10-2018 LH59_02800 7db09bb17675e0699360f9dc00b377c5 1032 Gene3D G3DSA:3.30.70.1430 558 653 9.9E-300 T 14-10-2018 LH59_02800 7db09bb17675e0699360f9dc00b377c5 1032 SUPERFAMILY SSF82693 556 653 6.28E-14 T 14-10-2018 LH59_02800 7db09bb17675e0699360f9dc00b377c5 1032 Pfam PF00873 AcrB/AcrD/AcrF family 4 1013 0.0 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_02800 7db09bb17675e0699360f9dc00b377c5 1032 Gene3D G3DSA:3.30.70.1320 135 326 9.9E-300 T 14-10-2018 LH59_02800 7db09bb17675e0699360f9dc00b377c5 1032 SUPERFAMILY SSF82866 797 1016 4.32E-45 T 14-10-2018 LH59_02800 7db09bb17675e0699360f9dc00b377c5 1032 Gene3D G3DSA:3.30.2090.10 706 794 9.9E-300 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_02800 7db09bb17675e0699360f9dc00b377c5 1032 SUPERFAMILY SSF82693 40 134 3.4E-23 T 14-10-2018 LH59_02800 7db09bb17675e0699360f9dc00b377c5 1032 Gene3D G3DSA:3.30.70.1430 40 802 9.9E-300 T 14-10-2018 LH59_02800 7db09bb17675e0699360f9dc00b377c5 1032 SUPERFAMILY SSF82714 708 792 8.63E-19 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_02800 7db09bb17675e0699360f9dc00b377c5 1032 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 1.5E-76 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_02800 7db09bb17675e0699360f9dc00b377c5 1032 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 1.5E-76 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_02800 7db09bb17675e0699360f9dc00b377c5 1032 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.5E-76 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_02800 7db09bb17675e0699360f9dc00b377c5 1032 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 1.5E-76 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_02800 7db09bb17675e0699360f9dc00b377c5 1032 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 1.5E-76 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_02800 7db09bb17675e0699360f9dc00b377c5 1032 PRINTS PR00702 Acriflavin resistance protein family signature 543 560 1.5E-76 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_02800 7db09bb17675e0699360f9dc00b377c5 1032 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.5E-76 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_02800 7db09bb17675e0699360f9dc00b377c5 1032 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 1.5E-76 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_02800 7db09bb17675e0699360f9dc00b377c5 1032 PRINTS PR00702 Acriflavin resistance protein family signature 610 624 1.5E-76 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_02800 7db09bb17675e0699360f9dc00b377c5 1032 Gene3D G3DSA:1.20.1640.10 504 1010 9.9E-300 T 14-10-2018 LH59_02800 7db09bb17675e0699360f9dc00b377c5 1032 SUPERFAMILY SSF82866 290 491 6.8E-47 T 14-10-2018 LH59_02800 7db09bb17675e0699360f9dc00b377c5 1032 Gene3D G3DSA:3.30.70.1440 654 852 9.9E-300 T 14-10-2018 LH59_02800 7db09bb17675e0699360f9dc00b377c5 1032 Gene3D G3DSA:3.30.2090.10 179 269 9.9E-300 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_02800 7db09bb17675e0699360f9dc00b377c5 1032 SUPERFAMILY SSF82714 183 266 1.03E-14 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_12840 8db75cddae4b6ed41ceda46e925dfb8d 686 Gene3D G3DSA:3.40.50.2000 462 650 6.9E-39 T 14-10-2018 LH59_12840 8db75cddae4b6ed41ceda46e925dfb8d 686 SUPERFAMILY SSF53756 247 662 2.98E-47 T 14-10-2018 LH59_12840 8db75cddae4b6ed41ceda46e925dfb8d 686 Pfam PF00534 Glycosyl transferases group 1 485 625 7.7E-21 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 LH59_12840 8db75cddae4b6ed41ceda46e925dfb8d 686 Gene3D G3DSA:3.40.50.2000 360 659 6.9E-39 T 14-10-2018 LH59_22190 fd0cb1383aea68e6d6c4067c269e963c 560 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 9 173 8.4E-53 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 LH59_22190 fd0cb1383aea68e6d6c4067c269e963c 560 SUPERFAMILY SSF52518 369 544 9.11E-61 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold LH59_22190 fd0cb1383aea68e6d6c4067c269e963c 560 Gene3D G3DSA:3.40.50.970 357 558 2.8E-60 T 14-10-2018 LH59_22190 fd0cb1383aea68e6d6c4067c269e963c 560 SUPERFAMILY SSF52518 9 180 9.97E-52 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold LH59_22190 fd0cb1383aea68e6d6c4067c269e963c 560 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 195 330 8.5E-26 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 LH59_22190 fd0cb1383aea68e6d6c4067c269e963c 560 SUPERFAMILY SSF52467 158 358 1.45E-36 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily LH59_22190 fd0cb1383aea68e6d6c4067c269e963c 560 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 425 444 - T 14-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 LH59_22190 fd0cb1383aea68e6d6c4067c269e963c 560 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 389 535 6.7E-45 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 LH59_22190 fd0cb1383aea68e6d6c4067c269e963c 560 Gene3D G3DSA:3.40.50.1220 187 356 1.7E-33 T 14-10-2018 LH59_22190 fd0cb1383aea68e6d6c4067c269e963c 560 Gene3D G3DSA:3.40.50.970 1 180 1.5E-60 T 14-10-2018 LH59_01940 c0375c3f870c3a8902c1513ea417877a 210 Pfam PF03861 ANTAR domain 148 200 1.5E-14 T 14-10-2018 IPR005561 ANTAR domain GO:0003723 LH59_01940 c0375c3f870c3a8902c1513ea417877a 210 Gene3D G3DSA:1.10.10.10 148 205 7.3E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_01940 c0375c3f870c3a8902c1513ea417877a 210 Gene3D G3DSA:3.40.50.2300 13 138 1.1E-42 T 14-10-2018 LH59_01940 c0375c3f870c3a8902c1513ea417877a 210 PIRSF PIRSF036382 14 207 3.4E-42 T 14-10-2018 IPR008327 Signal transduction response regulator, antiterminator LH59_01940 c0375c3f870c3a8902c1513ea417877a 210 SMART SM01012 145 200 1.6E-13 T 14-10-2018 IPR005561 ANTAR domain GO:0003723 LH59_01940 c0375c3f870c3a8902c1513ea417877a 210 SUPERFAMILY SSF52172 17 200 3.48E-38 T 14-10-2018 IPR011006 CheY-like superfamily LH59_26135 e62002f38abf6a1d9e8735d72a83f5f8 360 Gene3D G3DSA:1.20.58.410 4 95 4.3E-6 T 14-10-2018 LH59_26135 e62002f38abf6a1d9e8735d72a83f5f8 360 Gene3D G3DSA:3.30.70.1660 107 214 2.9E-44 T 14-10-2018 LH59_26135 e62002f38abf6a1d9e8735d72a83f5f8 360 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 5 357 41.134 T 14-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 LH59_26135 e62002f38abf6a1d9e8735d72a83f5f8 360 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 1 356 7.6E-161 T 14-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 LH59_26135 e62002f38abf6a1d9e8735d72a83f5f8 360 Pfam PF03462 PCRF domain 15 203 2.3E-71 T 14-10-2018 IPR005139 Peptide chain release factor GO:0006415 LH59_26135 e62002f38abf6a1d9e8735d72a83f5f8 360 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 228 244 - T 14-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 LH59_26135 e62002f38abf6a1d9e8735d72a83f5f8 360 Gene3D G3DSA:3.30.70.1660 288 360 1.3E-15 T 14-10-2018 LH59_26135 e62002f38abf6a1d9e8735d72a83f5f8 360 SMART SM00937 63 178 9.7E-65 T 14-10-2018 IPR005139 Peptide chain release factor GO:0006415 LH59_26135 e62002f38abf6a1d9e8735d72a83f5f8 360 SUPERFAMILY SSF75620 12 353 1.11E-136 T 14-10-2018 LH59_26135 e62002f38abf6a1d9e8735d72a83f5f8 360 Gene3D G3DSA:3.30.160.20 215 287 3.4E-36 T 14-10-2018 LH59_26135 e62002f38abf6a1d9e8735d72a83f5f8 360 Pfam PF00472 RF-1 domain 214 321 4.3E-43 T 14-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 LH59_15015 ccf14c844feaa44355ee3fbc940e0234 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 6.1E-16 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_15015 ccf14c844feaa44355ee3fbc940e0234 299 SUPERFAMILY SSF53850 90 297 1.46E-35 T 14-10-2018 LH59_15015 ccf14c844feaa44355ee3fbc940e0234 299 Gene3D G3DSA:1.10.10.10 2 91 1.2E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_15015 ccf14c844feaa44355ee3fbc940e0234 299 Gene3D G3DSA:3.40.190.10 165 270 1.1E-54 T 14-10-2018 LH59_15015 ccf14c844feaa44355ee3fbc940e0234 299 SUPERFAMILY SSF46785 3 111 1.12E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_15015 ccf14c844feaa44355ee3fbc940e0234 299 Gene3D G3DSA:3.40.190.10 92 294 1.1E-54 T 14-10-2018 LH59_15015 ccf14c844feaa44355ee3fbc940e0234 299 Pfam PF03466 LysR substrate binding domain 88 297 2.7E-33 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_22315 fe12f51e4328a2c4800f08ab6d680abd 348 Gene3D G3DSA:3.90.870.10 1 224 8.3E-70 T 14-10-2018 LH59_22315 fe12f51e4328a2c4800f08ab6d680abd 348 Pfam PF01300 Telomere recombination 20 208 4.3E-46 T 14-10-2018 IPR006070 YrdC-like domain GO:0003725 LH59_22315 fe12f51e4328a2c4800f08ab6d680abd 348 SUPERFAMILY SSF55821 11 219 1.25E-51 T 14-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily LH59_22315 fe12f51e4328a2c4800f08ab6d680abd 348 Gene3D G3DSA:3.40.50.11030 225 346 6.4E-12 T 14-10-2018 IPR038385 Threonylcarbamoyl-AMP synthase, C-terminal domain superfamily LH59_22315 fe12f51e4328a2c4800f08ab6d680abd 348 Pfam PF03481 Putative GTP-binding controlling metal-binding 210 339 1.4E-19 T 14-10-2018 IPR005145 Putative GTP-binding controlling metal-binding domain LH59_22315 fe12f51e4328a2c4800f08ab6d680abd 348 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 9 219 1.9E-47 T 14-10-2018 IPR006070 YrdC-like domain GO:0003725 LH59_22315 fe12f51e4328a2c4800f08ab6d680abd 348 PIRSF PIRSF004930 1 344 2.3E-94 T 14-10-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 LH59_20230 146ed7c2c29c77bc72bf40c7c8d5d5c3 341 Pfam PF03797 Autotransporter beta-domain 59 317 2.1E-41 T 14-10-2018 IPR005546 Autotransporter beta-domain LH59_20230 146ed7c2c29c77bc72bf40c7c8d5d5c3 341 Gene3D G3DSA:2.40.128.130 17 341 5.8E-82 T 14-10-2018 IPR036709 Autotransporter beta-domain superfamily LH59_20230 146ed7c2c29c77bc72bf40c7c8d5d5c3 341 SUPERFAMILY SSF103515 26 341 5.89E-38 T 14-10-2018 IPR036709 Autotransporter beta-domain superfamily LH59_20230 146ed7c2c29c77bc72bf40c7c8d5d5c3 341 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 17 341 2.8E-56 T 14-10-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 LH59_20230 146ed7c2c29c77bc72bf40c7c8d5d5c3 341 SMART SM00869 56 330 1.0E-28 T 14-10-2018 IPR005546 Autotransporter beta-domain LH59_12165 e0d649aba2df5ab6d36583f3a43c7881 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 108 126 6.7E-12 T 14-10-2018 LH59_12165 e0d649aba2df5ab6d36583f3a43c7881 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 256 278 6.7E-12 T 14-10-2018 LH59_12165 e0d649aba2df5ab6d36583f3a43c7881 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 6.7E-12 T 14-10-2018 LH59_12165 e0d649aba2df5ab6d36583f3a43c7881 319 Gene3D G3DSA:3.50.50.60 10 297 1.6E-92 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_12165 e0d649aba2df5ab6d36583f3a43c7881 319 Gene3D G3DSA:3.50.50.60 122 232 1.6E-92 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_12165 e0d649aba2df5ab6d36583f3a43c7881 319 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 10 291 1.1E-18 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LH59_12165 e0d649aba2df5ab6d36583f3a43c7881 319 SUPERFAMILY SSF51905 5 302 2.37E-30 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_12165 e0d649aba2df5ab6d36583f3a43c7881 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 11 33 2.0E-11 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 LH59_12165 e0d649aba2df5ab6d36583f3a43c7881 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 109 117 2.0E-11 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 LH59_12165 e0d649aba2df5ab6d36583f3a43c7881 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 266 284 2.0E-11 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 LH59_12165 e0d649aba2df5ab6d36583f3a43c7881 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 131 143 2.0E-11 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 LH59_10950 2bd83be48632975d69b5ff232893c15b 820 Gene3D G3DSA:3.40.1110.10 519 641 1.4E-79 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 LH59_10950 2bd83be48632975d69b5ff232893c15b 820 Pfam PF00122 E1-E2 ATPase 307 488 1.6E-57 T 14-10-2018 LH59_10950 2bd83be48632975d69b5ff232893c15b 820 Gene3D G3DSA:3.40.50.1000 489 762 1.4E-79 T 14-10-2018 IPR023214 HAD superfamily LH59_10950 2bd83be48632975d69b5ff232893c15b 820 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 256 812 1.0E-177 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 LH59_10950 2bd83be48632975d69b5ff232893c15b 820 Gene3D G3DSA:3.30.70.100 119 185 2.4E-5 T 14-10-2018 LH59_10950 2bd83be48632975d69b5ff232893c15b 820 SUPERFAMILY SSF55008 117 184 1.54E-10 T 14-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 LH59_10950 2bd83be48632975d69b5ff232893c15b 820 SUPERFAMILY SSF81653 309 407 1.28E-25 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 LH59_10950 2bd83be48632975d69b5ff232893c15b 820 Gene3D G3DSA:2.70.150.20 300 411 4.1E-39 T 14-10-2018 LH59_10950 2bd83be48632975d69b5ff232893c15b 820 PRINTS PR00941 Cadmium-transporting ATPase signature 291 311 1.9E-7 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 LH59_10950 2bd83be48632975d69b5ff232893c15b 820 PRINTS PR00941 Cadmium-transporting ATPase signature 392 406 1.9E-7 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 LH59_10950 2bd83be48632975d69b5ff232893c15b 820 PRINTS PR00941 Cadmium-transporting ATPase signature 373 389 1.9E-7 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 LH59_10950 2bd83be48632975d69b5ff232893c15b 820 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 656 666 4.4E-24 T 14-10-2018 LH59_10950 2bd83be48632975d69b5ff232893c15b 820 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 709 728 4.4E-24 T 14-10-2018 LH59_10950 2bd83be48632975d69b5ff232893c15b 820 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 508 522 4.4E-24 T 14-10-2018 LH59_10950 2bd83be48632975d69b5ff232893c15b 820 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 357 371 4.4E-24 T 14-10-2018 LH59_10950 2bd83be48632975d69b5ff232893c15b 820 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 733 745 4.4E-24 T 14-10-2018 LH59_10950 2bd83be48632975d69b5ff232893c15b 820 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 238 812 1.9E-122 T 14-10-2018 LH59_10950 2bd83be48632975d69b5ff232893c15b 820 SUPERFAMILY SSF56784 507 809 8.8E-53 T 14-10-2018 IPR036412 HAD-like superfamily LH59_10950 2bd83be48632975d69b5ff232893c15b 820 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 510 516 - T 14-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 LH59_10950 2bd83be48632975d69b5ff232893c15b 820 Pfam PF00702 haloacid dehalogenase-like hydrolase 505 723 1.3E-39 T 14-10-2018 LH59_10950 2bd83be48632975d69b5ff232893c15b 820 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 279 793 4.8E-76 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 LH59_10950 2bd83be48632975d69b5ff232893c15b 820 SUPERFAMILY SSF81665 257 500 1.44E-15 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 LH59_01265 8d93578218d55123386dc955d47d2cb0 347 Gene3D G3DSA:1.10.3470.10 21 347 3.8E-78 T 14-10-2018 IPR037294 ABC transporter, BtuC-like LH59_01265 8d93578218d55123386dc955d47d2cb0 347 SUPERFAMILY SSF81345 18 344 1.96E-62 T 14-10-2018 IPR037294 ABC transporter, BtuC-like LH59_01265 8d93578218d55123386dc955d47d2cb0 347 Pfam PF01032 FecCD transport family 36 343 8.6E-71 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 LH59_01475 0e7ddb918f9d4eed955cc149f4e00ef5 469 SUPERFAMILY SSF103473 20 456 6.15E-62 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_01475 0e7ddb918f9d4eed955cc149f4e00ef5 469 Gene3D G3DSA:1.20.1720.10 24 226 6.9E-43 T 14-10-2018 LH59_01475 0e7ddb918f9d4eed955cc149f4e00ef5 469 Pfam PF07690 Major Facilitator Superfamily 28 417 9.1E-52 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_01475 0e7ddb918f9d4eed955cc149f4e00ef5 469 Gene3D G3DSA:1.20.1250.20 264 456 2.0E-19 T 14-10-2018 LH59_07820 00a1d4e325050f9a9ee2e93040ab8e38 90 Gene3D G3DSA:4.10.640.10 5 90 4.5E-25 T 14-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_07820 00a1d4e325050f9a9ee2e93040ab8e38 90 SUPERFAMILY SSF46911 14 89 1.57E-27 T 14-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_07820 00a1d4e325050f9a9ee2e93040ab8e38 90 Pfam PF01084 Ribosomal protein S18 34 83 2.2E-22 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_07820 00a1d4e325050f9a9ee2e93040ab8e38 90 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 36 85 7.0E-22 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_07820 00a1d4e325050f9a9ee2e93040ab8e38 90 PRINTS PR00974 Ribosomal protein S18 family signature 53 60 6.3E-15 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_07820 00a1d4e325050f9a9ee2e93040ab8e38 90 PRINTS PR00974 Ribosomal protein S18 family signature 61 75 6.3E-15 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_07820 00a1d4e325050f9a9ee2e93040ab8e38 90 PRINTS PR00974 Ribosomal protein S18 family signature 43 53 6.3E-15 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_07820 00a1d4e325050f9a9ee2e93040ab8e38 90 PRINTS PR00974 Ribosomal protein S18 family signature 75 85 6.3E-15 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_07820 00a1d4e325050f9a9ee2e93040ab8e38 90 TIGRFAM TIGR00165 S18: ribosomal protein bS18 20 87 6.2E-33 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_07820 00a1d4e325050f9a9ee2e93040ab8e38 90 ProSitePatterns PS00057 Ribosomal protein S18 signature. 36 59 - T 14-10-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_07820 00a1d4e325050f9a9ee2e93040ab8e38 90 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 7 88 20.184 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_00635 9e93b1dcdbf734f7694810b1c68d8d5e 233 Pfam PF05036 Sporulation related domain 157 231 2.0E-14 T 14-10-2018 IPR007730 Sporulation-like domain GO:0042834 LH59_00635 9e93b1dcdbf734f7694810b1c68d8d5e 233 SUPERFAMILY SSF110997 157 232 2.88E-17 T 14-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 LH59_00635 9e93b1dcdbf734f7694810b1c68d8d5e 233 Gene3D G3DSA:3.30.70.1070 153 233 9.8E-16 T 14-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 LH59_13385 8ef13f54a45e2d3c1ae6e153079d4992 4100 Pfam PF12545 Filamentous haemagglutinin family outer membrane protein 3876 3986 2.7E-36 T 14-10-2018 IPR021026 Filamentous haemagglutinin family outer membrane protein, domain of unknown function DUF3739 LH59_13385 8ef13f54a45e2d3c1ae6e153079d4992 4100 Pfam PF05860 haemagglutination activity domain 161 254 3.7E-20 T 14-10-2018 IPR008638 Filamentous haemagglutinin, N-terminal LH59_13385 8ef13f54a45e2d3c1ae6e153079d4992 4100 SUPERFAMILY SSF51126 165 461 3.45E-30 T 14-10-2018 IPR011050 Pectin lyase fold/virulence factor LH59_13385 8ef13f54a45e2d3c1ae6e153079d4992 4100 SMART SM00912 146 256 9.7E-25 T 14-10-2018 IPR008638 Filamentous haemagglutinin, N-terminal LH59_13385 8ef13f54a45e2d3c1ae6e153079d4992 4100 Gene3D G3DSA:2.160.20.10 148 463 7.8E-47 T 14-10-2018 IPR012334 Pectin lyase fold LH59_13385 8ef13f54a45e2d3c1ae6e153079d4992 4100 TIGRFAM TIGR01901 adhes_NPXG: filamentous hemagglutinin family N-terminal domain 176 250 5.7E-21 T 14-10-2018 IPR008638 Filamentous haemagglutinin, N-terminal LH59_13385 8ef13f54a45e2d3c1ae6e153079d4992 4100 Gene3D G3DSA:2.160.20.10 816 1083 2.3E-8 T 14-10-2018 IPR012334 Pectin lyase fold LH59_07090 41aa92a0e066a4b908d18dffbae15310 465 SUPERFAMILY SSF54862 70 228 5.24E-5 T 14-10-2018 LH59_07090 41aa92a0e066a4b908d18dffbae15310 465 Pfam PF12801 4Fe-4S binding domain 65 100 6.6E-10 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain LH59_07090 41aa92a0e066a4b908d18dffbae15310 465 Pfam PF12801 4Fe-4S binding domain 161 184 4.5E-4 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain LH59_19720 86b2e45d161a525553483c51d8789144 378 SUPERFAMILY SSF111369 160 260 1.7E-8 T 14-10-2018 LH59_19720 86b2e45d161a525553483c51d8789144 378 Gene3D G3DSA:2.40.30.170 227 349 4.1E-34 T 14-10-2018 LH59_19720 86b2e45d161a525553483c51d8789144 378 Gene3D G3DSA:2.40.50.100 54 122 5.7E-5 T 14-10-2018 LH59_19720 86b2e45d161a525553483c51d8789144 378 Pfam PF13437 HlyD family secretion protein 211 289 5.3E-12 T 14-10-2018 LH59_19720 86b2e45d161a525553483c51d8789144 378 SUPERFAMILY SSF111369 54 138 4.45E-6 T 14-10-2018 LH59_26495 dfb6c6fc5250f41379bad9ef20913b8a 313 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 313 33.58 T 14-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 LH59_26495 dfb6c6fc5250f41379bad9ef20913b8a 313 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 140 163 - T 14-10-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 LH59_26495 dfb6c6fc5250f41379bad9ef20913b8a 313 Gene3D G3DSA:3.40.50.170 1 213 1.5E-73 T 14-10-2018 LH59_26495 dfb6c6fc5250f41379bad9ef20913b8a 313 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 1 310 7.6E-78 T 14-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 LH59_26495 dfb6c6fc5250f41379bad9ef20913b8a 313 Pfam PF02911 Formyl transferase, C-terminal domain 211 309 3.2E-18 T 14-10-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 LH59_26495 dfb6c6fc5250f41379bad9ef20913b8a 313 Gene3D G3DSA:3.10.25.10 214 312 2.7E-21 T 14-10-2018 IPR037022 Formyl transferase, C-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 LH59_26495 dfb6c6fc5250f41379bad9ef20913b8a 313 Pfam PF00551 Formyl transferase 2 188 1.1E-40 T 14-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 LH59_26495 dfb6c6fc5250f41379bad9ef20913b8a 313 SUPERFAMILY SSF50486 212 311 1.06E-21 T 14-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 LH59_26495 dfb6c6fc5250f41379bad9ef20913b8a 313 SUPERFAMILY SSF53328 1 211 2.62E-63 T 14-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 LH59_05030 aa55030c170f843c981faed80bf47ff5 529 Gene3D G3DSA:3.40.140.20 395 529 2.7E-57 T 14-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 LH59_05030 aa55030c170f843c981faed80bf47ff5 529 PIRSF PIRSF000414 1 529 1.0E-210 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 LH59_05030 aa55030c170f843c981faed80bf47ff5 529 SUPERFAMILY SSF53927 224 529 8.32E-127 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 LH59_05030 aa55030c170f843c981faed80bf47ff5 529 SUPERFAMILY SSF52335 3 198 1.2E-64 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily LH59_05030 aa55030c170f843c981faed80bf47ff5 529 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 3 529 43.498 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 LH59_05030 aa55030c170f843c981faed80bf47ff5 529 Pfam PF02142 MGS-like domain 15 129 2.9E-28 T 14-10-2018 IPR011607 Methylglyoxal synthase-like domain LH59_05030 aa55030c170f843c981faed80bf47ff5 529 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 5 529 3.2E-218 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 LH59_05030 aa55030c170f843c981faed80bf47ff5 529 Pfam PF01808 AICARFT/IMPCHase bienzyme 135 459 1.4E-115 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 LH59_05030 aa55030c170f843c981faed80bf47ff5 529 SMART SM00798 135 461 6.9E-198 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 LH59_05030 aa55030c170f843c981faed80bf47ff5 529 Gene3D G3DSA:3.40.50.1380 1 202 1.2E-80 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily LH59_05030 aa55030c170f843c981faed80bf47ff5 529 SMART SM00851 15 130 1.8E-56 T 14-10-2018 IPR011607 Methylglyoxal synthase-like domain LH59_05030 aa55030c170f843c981faed80bf47ff5 529 Gene3D G3DSA:3.40.140.20 220 375 4.0E-59 T 14-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 LH59_07260 72ca57824ba6f4ad8b28c5840b099cec 889 Gene3D G3DSA:3.90.199.10 33 522 3.3E-223 T 14-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 LH59_07260 72ca57824ba6f4ad8b28c5840b099cec 889 SUPERFAMILY SSF56719 30 523 1.7E-178 T 14-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 LH59_07260 72ca57824ba6f4ad8b28c5840b099cec 889 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 32 513 8.6E-156 T 14-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 LH59_07260 72ca57824ba6f4ad8b28c5840b099cec 889 Gene3D G3DSA:1.10.268.10 370 500 3.3E-223 T 14-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 LH59_07260 72ca57824ba6f4ad8b28c5840b099cec 889 Gene3D G3DSA:3.30.1360.40 236 333 3.3E-223 T 14-10-2018 LH59_07260 72ca57824ba6f4ad8b28c5840b099cec 889 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 10 852 0.0 T 14-10-2018 LH59_07260 72ca57824ba6f4ad8b28c5840b099cec 889 SMART SM00434 11 506 1.6E-290 T 14-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 LH59_07260 72ca57824ba6f4ad8b28c5840b099cec 889 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 704 749 3.4E-13 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 LH59_07260 72ca57824ba6f4ad8b28c5840b099cec 889 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 656 699 3.0E-10 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 LH59_07260 72ca57824ba6f4ad8b28c5840b099cec 889 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 549 594 1.8E-9 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 LH59_07260 72ca57824ba6f4ad8b28c5840b099cec 889 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 599 648 1.4E-9 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 LH59_07260 72ca57824ba6f4ad8b28c5840b099cec 889 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 805 851 1.4E-11 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 LH59_07260 72ca57824ba6f4ad8b28c5840b099cec 889 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 755 801 2.1E-12 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 LH59_07260 72ca57824ba6f4ad8b28c5840b099cec 889 Gene3D G3DSA:2.120.10.90 542 852 4.2E-124 T 14-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal LH59_07260 72ca57824ba6f4ad8b28c5840b099cec 889 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 2 853 24.056 T 14-10-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 LH59_07260 72ca57824ba6f4ad8b28c5840b099cec 889 SUPERFAMILY SSF101904 544 864 2.09E-111 T 14-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal LH59_21685 235d84da5fbad8f34ca064b60b60b9d5 360 SUPERFAMILY SSF46689 242 292 8.96E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_21685 235d84da5fbad8f34ca064b60b60b9d5 360 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 295 337 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 LH59_21685 235d84da5fbad8f34ca064b60b60b9d5 360 SMART SM00342 258 341 2.0E-29 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_21685 235d84da5fbad8f34ca064b60b60b9d5 360 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 310 325 1.9E-6 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 LH59_21685 235d84da5fbad8f34ca064b60b60b9d5 360 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 325 341 1.9E-6 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 LH59_21685 235d84da5fbad8f34ca064b60b60b9d5 360 Pfam PF01965 DJ-1/PfpI family 68 202 2.1E-13 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 LH59_21685 235d84da5fbad8f34ca064b60b60b9d5 360 SUPERFAMILY SSF52317 29 219 2.45E-41 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_21685 235d84da5fbad8f34ca064b60b60b9d5 360 Pfam PF12833 Helix-turn-helix domain 264 342 1.1E-25 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_21685 235d84da5fbad8f34ca064b60b60b9d5 360 Gene3D G3DSA:3.40.50.880 26 229 1.2E-49 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_21685 235d84da5fbad8f34ca064b60b60b9d5 360 Gene3D G3DSA:1.10.10.60 238 347 2.1E-31 T 14-10-2018 LH59_21685 235d84da5fbad8f34ca064b60b60b9d5 360 SUPERFAMILY SSF46689 294 345 7.17E-13 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_10550 71144ed9b66a37dfaaae7be551e576e3 320 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 17 185 1.9E-41 T 14-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 LH59_10550 71144ed9b66a37dfaaae7be551e576e3 320 Gene3D G3DSA:1.10.1040.10 192 310 1.3E-32 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 LH59_10550 71144ed9b66a37dfaaae7be551e576e3 320 Gene3D G3DSA:3.40.50.720 2 187 5.7E-47 T 14-10-2018 LH59_10550 71144ed9b66a37dfaaae7be551e576e3 320 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 190 288 7.3E-18 T 14-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 LH59_10550 71144ed9b66a37dfaaae7be551e576e3 320 SUPERFAMILY SSF48179 189 294 7.23E-22 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 LH59_10550 71144ed9b66a37dfaaae7be551e576e3 320 SUPERFAMILY SSF51735 15 185 1.62E-39 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_10550 71144ed9b66a37dfaaae7be551e576e3 320 PIRSF PIRSF000105 9 312 1.8E-69 T 14-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 LH59_02820 e93ff42f894ccef1d43ac85cd6a0929e 417 SUPERFAMILY SSF51905 1 415 7.38E-44 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_02820 e93ff42f894ccef1d43ac85cd6a0929e 417 Gene3D G3DSA:3.30.9.10 134 361 1.6E-46 T 14-10-2018 LH59_02820 e93ff42f894ccef1d43ac85cd6a0929e 417 Gene3D G3DSA:3.50.50.60 102 401 1.6E-46 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_02820 e93ff42f894ccef1d43ac85cd6a0929e 417 SUPERFAMILY SSF54373 272 362 3.53E-10 T 14-10-2018 LH59_02820 e93ff42f894ccef1d43ac85cd6a0929e 417 Gene3D G3DSA:3.50.50.60 1 78 2.6E-11 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_02820 e93ff42f894ccef1d43ac85cd6a0929e 417 Pfam PF01266 FAD dependent oxidoreductase 2 400 2.6E-60 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 LH59_07960 c0a7b5e3c50307eb307a7c2ce19c2694 229 Gene3D G3DSA:1.10.10.10 124 226 2.2E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_07960 c0a7b5e3c50307eb307a7c2ce19c2694 229 SMART SM00862 145 218 7.5E-23 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_07960 c0a7b5e3c50307eb307a7c2ce19c2694 229 Pfam PF00072 Response regulator receiver domain 3 112 8.2E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_07960 c0a7b5e3c50307eb307a7c2ce19c2694 229 SUPERFAMILY SSF46894 120 219 3.68E-25 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LH59_07960 c0a7b5e3c50307eb307a7c2ce19c2694 229 SMART SM00448 1 112 2.2E-35 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_07960 c0a7b5e3c50307eb307a7c2ce19c2694 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 218 6.4E-22 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_07960 c0a7b5e3c50307eb307a7c2ce19c2694 229 SUPERFAMILY SSF52172 1 120 3.84E-36 T 14-10-2018 IPR011006 CheY-like superfamily LH59_07960 c0a7b5e3c50307eb307a7c2ce19c2694 229 Gene3D G3DSA:3.40.50.2300 1 121 5.6E-38 T 14-10-2018 LH59_01270 9b765c23b3cc7936bfd5eb675c6507a6 262 SUPERFAMILY SSF52540 3 232 1.41E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_01270 9b765c23b3cc7936bfd5eb675c6507a6 262 Pfam PF00005 ABC transporter 19 166 3.3E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_01270 9b765c23b3cc7936bfd5eb675c6507a6 262 Gene3D G3DSA:3.40.50.300 3 255 1.3E-69 T 14-10-2018 LH59_01270 9b765c23b3cc7936bfd5eb675c6507a6 262 SMART SM00382 27 216 2.0E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_08235 8e9e02f2ef7b8105885a102b63781513 152 PIRSF PIRSF000027 6 151 1.0E-46 T 14-10-2018 IPR012127 Cytochrome c prime GO:0005506|GO:0009055|GO:0020037|GO:0042597 LH59_08235 8e9e02f2ef7b8105885a102b63781513 152 SUPERFAMILY SSF47175 27 149 4.56E-41 T 14-10-2018 IPR010980 Cytochrome c/b562 GO:0005506|GO:0009055|GO:0020037|GO:0022900 LH59_08235 8e9e02f2ef7b8105885a102b63781513 152 Pfam PF01322 Cytochrome C' 32 149 5.1E-37 T 14-10-2018 IPR002321 Cytochrome c, class II GO:0005506|GO:0009055|GO:0020037 LH59_08235 8e9e02f2ef7b8105885a102b63781513 152 Gene3D G3DSA:1.20.120.10 26 152 7.1E-50 T 14-10-2018 LH59_08235 8e9e02f2ef7b8105885a102b63781513 152 PRINTS PR00608 Class II cytochrome C signature 115 138 4.9E-9 T 14-10-2018 IPR015984 Cytochrome c prime, subgroup LH59_08235 8e9e02f2ef7b8105885a102b63781513 152 PRINTS PR00608 Class II cytochrome C signature 138 149 4.9E-9 T 14-10-2018 IPR015984 Cytochrome c prime, subgroup LH59_00255 f15a08ea65f7df721259133085f33761 308 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 178 301 4.7E-25 T 14-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain LH59_00255 f15a08ea65f7df721259133085f33761 308 Gene3D G3DSA:1.10.1040.10 178 303 3.1E-24 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 LH59_00255 f15a08ea65f7df721259133085f33761 308 SUPERFAMILY SSF48179 178 302 4.08E-28 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 LH59_00255 f15a08ea65f7df721259133085f33761 308 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 6 305 5.3E-60 T 14-10-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 LH59_00255 f15a08ea65f7df721259133085f33761 308 SUPERFAMILY SSF51735 1 131 1.46E-10 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_00255 f15a08ea65f7df721259133085f33761 308 Gene3D G3DSA:3.40.50.720 1 173 1.1E-47 T 14-10-2018 LH59_00255 f15a08ea65f7df721259133085f33761 308 Pfam PF02558 Ketopantoate reductase PanE/ApbA 5 150 1.4E-33 T 14-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain LH59_27935 b4927f9ef75b6cea3c5c5f0877090e41 125 SUPERFAMILY SSF50249 2 124 1.29E-52 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_27935 b4927f9ef75b6cea3c5c5f0877090e41 125 PRINTS PR01034 Ribosomal protein S12 signature 58 77 6.1E-61 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_27935 b4927f9ef75b6cea3c5c5f0877090e41 125 PRINTS PR01034 Ribosomal protein S12 signature 77 94 6.1E-61 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_27935 b4927f9ef75b6cea3c5c5f0877090e41 125 PRINTS PR01034 Ribosomal protein S12 signature 110 122 6.1E-61 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_27935 b4927f9ef75b6cea3c5c5f0877090e41 125 PRINTS PR01034 Ribosomal protein S12 signature 27 42 6.1E-61 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_27935 b4927f9ef75b6cea3c5c5f0877090e41 125 PRINTS PR01034 Ribosomal protein S12 signature 42 57 6.1E-61 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_27935 b4927f9ef75b6cea3c5c5f0877090e41 125 PRINTS PR01034 Ribosomal protein S12 signature 94 110 6.1E-61 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_27935 b4927f9ef75b6cea3c5c5f0877090e41 125 Gene3D G3DSA:2.40.50.140 1 125 7.2E-63 T 14-10-2018 LH59_27935 b4927f9ef75b6cea3c5c5f0877090e41 125 Pfam PF00164 Ribosomal protein S12/S23 15 123 3.6E-43 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_27935 b4927f9ef75b6cea3c5c5f0877090e41 125 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_27935 b4927f9ef75b6cea3c5c5f0877090e41 125 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 124 3.0E-69 T 14-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_27935 b4927f9ef75b6cea3c5c5f0877090e41 125 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 39.348 T 14-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_27935 b4927f9ef75b6cea3c5c5f0877090e41 125 PIRSF PIRSF002133 1 124 3.4E-55 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_09360 eb8b4dd77e864ab4fdc3b1a8b1614976 488 Gene3D G3DSA:3.20.20.450 236 487 6.5E-90 T 14-10-2018 IPR035919 EAL domain superfamily LH59_09360 eb8b4dd77e864ab4fdc3b1a8b1614976 488 SMART SM00052 234 479 4.2E-101 T 14-10-2018 IPR001633 EAL domain LH59_09360 eb8b4dd77e864ab4fdc3b1a8b1614976 488 Gene3D G3DSA:3.30.70.270 36 228 5.7E-18 T 14-10-2018 LH59_09360 eb8b4dd77e864ab4fdc3b1a8b1614976 488 SMART SM00267 49 224 1.3E-4 T 14-10-2018 IPR000160 GGDEF domain LH59_09360 eb8b4dd77e864ab4fdc3b1a8b1614976 488 Pfam PF00990 Diguanylate cyclase, GGDEF domain 93 217 1.4E-10 T 14-10-2018 IPR000160 GGDEF domain LH59_09360 eb8b4dd77e864ab4fdc3b1a8b1614976 488 SUPERFAMILY SSF141868 242 483 2.35E-83 T 14-10-2018 IPR035919 EAL domain superfamily LH59_09360 eb8b4dd77e864ab4fdc3b1a8b1614976 488 SUPERFAMILY SSF55073 94 225 5.49E-14 T 14-10-2018 IPR029787 Nucleotide cyclase LH59_09360 eb8b4dd77e864ab4fdc3b1a8b1614976 488 Pfam PF00563 EAL domain 245 474 2.8E-70 T 14-10-2018 IPR001633 EAL domain LH59_00955 63b1920edbef4c5f7328ebb03609a4dd 195 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 61 74 - T 14-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 LH59_00955 63b1920edbef4c5f7328ebb03609a4dd 195 SUPERFAMILY SSF54211 87 179 1.19E-33 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold LH59_00955 63b1920edbef4c5f7328ebb03609a4dd 195 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 31 174 4.8E-62 T 14-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 LH59_00955 63b1920edbef4c5f7328ebb03609a4dd 195 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 156 168 - T 14-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 LH59_00955 63b1920edbef4c5f7328ebb03609a4dd 195 SUPERFAMILY SSF54211 1 85 1.23E-33 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold LH59_00955 63b1920edbef4c5f7328ebb03609a4dd 195 Gene3D G3DSA:3.30.230.40 90 195 6.1E-39 T 14-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 LH59_00955 63b1920edbef4c5f7328ebb03609a4dd 195 Gene3D G3DSA:3.30.230.40 1 89 6.5E-37 T 14-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 LH59_00955 63b1920edbef4c5f7328ebb03609a4dd 195 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 2 195 42.078 T 14-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 LH59_25280 14098e2a93b40ac3512579e01c0a4ee6 351 SUPERFAMILY SSF117396 57 349 4.58E-45 T 14-10-2018 IPR036520 UPF0759 superfamily LH59_25280 14098e2a93b40ac3512579e01c0a4ee6 351 Pfam PF01904 Protein of unknown function DUF72 79 347 6.5E-39 T 14-10-2018 IPR002763 Protein of unknown function DUF72 LH59_25280 14098e2a93b40ac3512579e01c0a4ee6 351 Gene3D G3DSA:3.20.20.410 49 350 1.6E-27 T 14-10-2018 IPR036520 UPF0759 superfamily LH59_10670 ac40115a8d57b3eaa19d1ba8be3dbbc2 291 Pfam PF03466 LysR substrate binding domain 91 287 1.1E-29 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_10670 ac40115a8d57b3eaa19d1ba8be3dbbc2 291 Gene3D G3DSA:3.40.190.290 92 290 2.4E-31 T 14-10-2018 LH59_10670 ac40115a8d57b3eaa19d1ba8be3dbbc2 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 4.8E-22 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_10670 ac40115a8d57b3eaa19d1ba8be3dbbc2 291 Gene3D G3DSA:1.10.10.10 5 91 5.0E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_10670 ac40115a8d57b3eaa19d1ba8be3dbbc2 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 3.2E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_10670 ac40115a8d57b3eaa19d1ba8be3dbbc2 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 3.2E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_10670 ac40115a8d57b3eaa19d1ba8be3dbbc2 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 3.2E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_10670 ac40115a8d57b3eaa19d1ba8be3dbbc2 291 SUPERFAMILY SSF46785 6 113 2.21E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_10670 ac40115a8d57b3eaa19d1ba8be3dbbc2 291 SUPERFAMILY SSF53850 92 290 6.42E-31 T 14-10-2018 LH59_25250 79a811046efa0ce6bdd937c4a29e1c30 348 Pfam PF04055 Radical SAM superfamily 101 260 3.5E-10 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 LH59_25250 79a811046efa0ce6bdd937c4a29e1c30 348 SUPERFAMILY SSF102114 99 309 1.96E-12 T 14-10-2018 LH59_25250 79a811046efa0ce6bdd937c4a29e1c30 348 Gene3D G3DSA:3.20.20.70 65 318 1.1E-65 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_25250 79a811046efa0ce6bdd937c4a29e1c30 348 PIRSF PIRSF006004 1 345 1.9E-91 T 14-10-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 LH59_20800 49c561707d3772a153895d6d33754fce 485 SUPERFAMILY SSF56024 272 470 4.71E-46 T 14-10-2018 LH59_20800 49c561707d3772a153895d6d33754fce 485 Pfam PF13091 PLD-like domain 328 450 1.6E-24 T 14-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 LH59_20800 49c561707d3772a153895d6d33754fce 485 Pfam PF13091 PLD-like domain 137 280 2.0E-16 T 14-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 LH59_20800 49c561707d3772a153895d6d33754fce 485 PIRSF PIRSF000850 315 375 0.13 T 14-10-2018 LH59_20800 49c561707d3772a153895d6d33754fce 485 PIRSF PIRSF000850 119 191 0.1 T 14-10-2018 LH59_20800 49c561707d3772a153895d6d33754fce 485 PIRSF PIRSF000850 370 460 2.6E-5 T 14-10-2018 LH59_20800 49c561707d3772a153895d6d33754fce 485 SMART SM00155 220 247 8.3 T 14-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 LH59_20800 49c561707d3772a153895d6d33754fce 485 SMART SM00155 398 425 7.4E-6 T 14-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 LH59_20800 49c561707d3772a153895d6d33754fce 485 Gene3D G3DSA:3.30.870.10 115 302 3.1E-40 T 14-10-2018 LH59_20800 49c561707d3772a153895d6d33754fce 485 Gene3D G3DSA:3.30.870.10 304 482 9.2E-26 T 14-10-2018 LH59_20800 49c561707d3772a153895d6d33754fce 485 SUPERFAMILY SSF56024 111 316 1.52E-49 T 14-10-2018 LH59_25285 57c750e2159e42cc5a77cc3e12de5d40 486 Pfam PF01425 Amidase 27 458 1.8E-80 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_25285 57c750e2159e42cc5a77cc3e12de5d40 486 SUPERFAMILY SSF75304 2 469 3.01E-112 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_25285 57c750e2159e42cc5a77cc3e12de5d40 486 Gene3D G3DSA:3.90.1300.10 4 485 2.1E-132 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_25285 57c750e2159e42cc5a77cc3e12de5d40 486 ProSitePatterns PS00571 Amidases signature. 149 180 - T 14-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 LH59_06675 479581a1d649cba04053c35418a3ba9d 659 ProSitePatterns PS00455 Putative AMP-binding domain signature. 268 279 - T 14-10-2018 IPR020845 AMP-binding, conserved site LH59_06675 479581a1d649cba04053c35418a3ba9d 659 Gene3D G3DSA:3.40.50.12780 60 527 3.0E-106 T 14-10-2018 LH59_06675 479581a1d649cba04053c35418a3ba9d 659 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 33 88 2.6E-18 T 14-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 LH59_06675 479581a1d649cba04053c35418a3ba9d 659 Pfam PF00501 AMP-binding enzyme 96 534 1.4E-94 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 LH59_06675 479581a1d649cba04053c35418a3ba9d 659 SUPERFAMILY SSF56801 17 655 2.75E-171 T 14-10-2018 LH59_06675 479581a1d649cba04053c35418a3ba9d 659 Pfam PF13193 AMP-binding enzyme C-terminal domain 543 624 9.4E-28 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain LH59_06675 479581a1d649cba04053c35418a3ba9d 659 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 10 659 51.535 T 14-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 LH59_06675 479581a1d649cba04053c35418a3ba9d 659 Gene3D G3DSA:3.30.300.30 530 659 3.3E-29 T 14-10-2018 LH59_06675 479581a1d649cba04053c35418a3ba9d 659 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 29 657 5.0E-295 T 14-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 LH59_24460 0ae8c6f91501302e80f69319995c5086 188 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 4 182 2.1E-38 T 14-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 LH59_24460 0ae8c6f91501302e80f69319995c5086 188 Gene3D G3DSA:3.40.50.150 1 186 7.6E-49 T 14-10-2018 LH59_24460 0ae8c6f91501302e80f69319995c5086 188 Pfam PF03602 Conserved hypothetical protein 95 6 181 1.0E-45 T 14-10-2018 LH59_24460 0ae8c6f91501302e80f69319995c5086 188 PIRSF PIRSF004553 5 185 5.8E-39 T 14-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 LH59_24460 0ae8c6f91501302e80f69319995c5086 188 SUPERFAMILY SSF53335 5 180 6.59E-42 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_24460 0ae8c6f91501302e80f69319995c5086 188 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 123 129 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 LH59_22795 5d8a41ab3aa86da7f1feee0f1ba341db 543 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 68 489 3.2E-88 T 14-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 LH59_22795 5d8a41ab3aa86da7f1feee0f1ba341db 543 Pfam PF00795 Carbon-nitrogen hydrolase 244 513 9.0E-23 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 LH59_22795 5d8a41ab3aa86da7f1feee0f1ba341db 543 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 9 527 20.941 T 14-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 LH59_22795 5d8a41ab3aa86da7f1feee0f1ba341db 543 Gene3D G3DSA:3.60.110.10 255 507 3.0E-12 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily LH59_22795 5d8a41ab3aa86da7f1feee0f1ba341db 543 SUPERFAMILY SSF56317 236 519 7.59E-32 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily LH59_26835 14b5c294e1f12e453e9eb48e10540f66 240 Pfam PF00005 ABC transporter 17 166 2.4E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_26835 14b5c294e1f12e453e9eb48e10540f66 240 SMART SM00382 26 217 3.3E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_26835 14b5c294e1f12e453e9eb48e10540f66 240 Gene3D G3DSA:3.40.50.300 1 239 1.1E-59 T 14-10-2018 LH59_26835 14b5c294e1f12e453e9eb48e10540f66 240 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_26835 14b5c294e1f12e453e9eb48e10540f66 240 SUPERFAMILY SSF52540 2 236 1.2E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_07660 523c2a63e28d9589cfdf4e16a0f5f25f 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 1.1E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_07660 523c2a63e28d9589cfdf4e16a0f5f25f 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 1.1E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_07660 523c2a63e28d9589cfdf4e16a0f5f25f 286 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.1E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_07660 523c2a63e28d9589cfdf4e16a0f5f25f 286 SUPERFAMILY SSF46785 4 110 1.1E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_07660 523c2a63e28d9589cfdf4e16a0f5f25f 286 Gene3D G3DSA:3.40.190.10 168 259 3.6E-35 T 14-10-2018 LH59_07660 523c2a63e28d9589cfdf4e16a0f5f25f 286 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 2.9E-19 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_07660 523c2a63e28d9589cfdf4e16a0f5f25f 286 Pfam PF03466 LysR substrate binding domain 90 261 4.8E-23 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_07660 523c2a63e28d9589cfdf4e16a0f5f25f 286 Gene3D G3DSA:1.10.10.10 2 86 6.6E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_07660 523c2a63e28d9589cfdf4e16a0f5f25f 286 Gene3D G3DSA:3.40.190.10 99 264 3.6E-35 T 14-10-2018 LH59_07660 523c2a63e28d9589cfdf4e16a0f5f25f 286 SUPERFAMILY SSF53850 90 283 6.52E-22 T 14-10-2018 LH59_11095 b0a643bb2234ad12a387a9b0ed55a166 142 Gene3D G3DSA:3.30.700.10 36 140 6.0E-37 T 14-10-2018 LH59_11095 b0a643bb2234ad12a387a9b0ed55a166 142 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 11 33 3.7E-9 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site LH59_11095 b0a643bb2234ad12a387a9b0ed55a166 142 TIGRFAM TIGR01710 typeII_sec_gspG: type II secretion system protein G 12 141 1.9E-53 T 14-10-2018 IPR010054 General secretion pathway protein G GO:0008565|GO:0015627|GO:0015628 LH59_11095 b0a643bb2234ad12a387a9b0ed55a166 142 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 12 32 - T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site LH59_11095 b0a643bb2234ad12a387a9b0ed55a166 142 Pfam PF07963 Prokaryotic N-terminal methylation motif 9 33 3.0E-9 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site LH59_11095 b0a643bb2234ad12a387a9b0ed55a166 142 SUPERFAMILY SSF54523 40 141 1.05E-35 T 14-10-2018 LH59_11095 b0a643bb2234ad12a387a9b0ed55a166 142 Pfam PF08334 Type II secretion system (T2SS), protein G 36 140 2.5E-41 T 14-10-2018 IPR013545 Type II secretion system protein G LH59_11095 b0a643bb2234ad12a387a9b0ed55a166 142 PRINTS PR00813 Bacterial general secretion pathway protein G signature 13 38 1.5E-16 T 14-10-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 LH59_11095 b0a643bb2234ad12a387a9b0ed55a166 142 PRINTS PR00813 Bacterial general secretion pathway protein G signature 49 67 1.5E-16 T 14-10-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 LH59_26815 0f926b9ebc88b89cbf2feae9381c83b4 313 Gene3D G3DSA:3.40.190.10 110 294 2.6E-47 T 14-10-2018 LH59_26815 0f926b9ebc88b89cbf2feae9381c83b4 313 Gene3D G3DSA:1.10.10.10 14 101 3.2E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_26815 0f926b9ebc88b89cbf2feae9381c83b4 313 SUPERFAMILY SSF53850 102 301 4.16E-35 T 14-10-2018 LH59_26815 0f926b9ebc88b89cbf2feae9381c83b4 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 16 74 7.6E-16 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_26815 0f926b9ebc88b89cbf2feae9381c83b4 313 SUPERFAMILY SSF46785 12 90 8.71E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_26815 0f926b9ebc88b89cbf2feae9381c83b4 313 Gene3D G3DSA:3.40.190.10 170 267 2.6E-47 T 14-10-2018 LH59_26815 0f926b9ebc88b89cbf2feae9381c83b4 313 Pfam PF03466 LysR substrate binding domain 102 298 2.2E-29 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_13915 55a81709ced3913fa17589af1e84178d 314 SUPERFAMILY SSF53850 92 294 3.72E-37 T 14-10-2018 LH59_13915 55a81709ced3913fa17589af1e84178d 314 Gene3D G3DSA:1.10.10.10 1 92 2.3E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_13915 55a81709ced3913fa17589af1e84178d 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.9E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_13915 55a81709ced3913fa17589af1e84178d 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.9E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_13915 55a81709ced3913fa17589af1e84178d 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.9E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_13915 55a81709ced3913fa17589af1e84178d 314 Gene3D G3DSA:3.40.190.290 93 294 5.6E-37 T 14-10-2018 LH59_13915 55a81709ced3913fa17589af1e84178d 314 Pfam PF03466 LysR substrate binding domain 90 287 6.0E-39 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_13915 55a81709ced3913fa17589af1e84178d 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 60 1.9E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_13915 55a81709ced3913fa17589af1e84178d 314 SUPERFAMILY SSF46785 1 80 1.31E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_01830 44cacfee5d1f803742ad4dc86433afdc 506 Gene3D G3DSA:3.60.120.10 1 502 3.2E-170 T 14-10-2018 IPR005801 ADC synthase GO:0009058 LH59_01830 44cacfee5d1f803742ad4dc86433afdc 506 PRINTS PR00095 Anthranilate synthase component I signature 429 443 4.3E-22 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 LH59_01830 44cacfee5d1f803742ad4dc86433afdc 506 PRINTS PR00095 Anthranilate synthase component I signature 444 458 4.3E-22 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 LH59_01830 44cacfee5d1f803742ad4dc86433afdc 506 PRINTS PR00095 Anthranilate synthase component I signature 335 348 4.3E-22 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 LH59_01830 44cacfee5d1f803742ad4dc86433afdc 506 PRINTS PR00095 Anthranilate synthase component I signature 349 362 4.3E-22 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 LH59_01830 44cacfee5d1f803742ad4dc86433afdc 506 Pfam PF00425 chorismate binding enzyme 226 487 1.6E-93 T 14-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal LH59_01830 44cacfee5d1f803742ad4dc86433afdc 506 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 26 495 2.5E-157 T 14-10-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 LH59_01830 44cacfee5d1f803742ad4dc86433afdc 506 Pfam PF04715 Anthranilate synthase component I, N terminal region 26 177 4.3E-26 T 14-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 LH59_01830 44cacfee5d1f803742ad4dc86433afdc 506 SUPERFAMILY SSF56322 14 495 4.06E-151 T 14-10-2018 IPR005801 ADC synthase GO:0009058 LH59_22495 39326ff574d817bf4a25ff544c251a82 200 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 2 147 4.9E-34 T 14-10-2018 IPR001453 MoaB/Mog domain LH59_22495 39326ff574d817bf4a25ff544c251a82 200 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 65 78 - T 14-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 LH59_22495 39326ff574d817bf4a25ff544c251a82 200 SMART SM00852 3 153 1.8E-21 T 14-10-2018 IPR001453 MoaB/Mog domain LH59_22495 39326ff574d817bf4a25ff544c251a82 200 Gene3D G3DSA:3.40.980.10 2 195 7.3E-59 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily LH59_22495 39326ff574d817bf4a25ff544c251a82 200 SUPERFAMILY SSF53218 2 188 1.7E-44 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily LH59_22495 39326ff574d817bf4a25ff544c251a82 200 Pfam PF00994 Probable molybdopterin binding domain 4 147 2.7E-28 T 14-10-2018 IPR001453 MoaB/Mog domain LH59_17655 b62b43ac228a70a196cd2689e3a0a6b7 439 Gene3D G3DSA:1.10.760.10 119 259 3.6E-36 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_17655 b62b43ac228a70a196cd2689e3a0a6b7 439 Pfam PF03150 Di-haem cytochrome c peroxidase 119 300 2.4E-41 T 14-10-2018 IPR004852 Di-haem cytochrome c peroxidase GO:0016491|GO:0055114 LH59_17655 b62b43ac228a70a196cd2689e3a0a6b7 439 Gene3D G3DSA:1.10.760.10 266 439 1.3E-40 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_17655 b62b43ac228a70a196cd2689e3a0a6b7 439 SUPERFAMILY SSF46626 277 439 3.77E-32 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_17655 b62b43ac228a70a196cd2689e3a0a6b7 439 SUPERFAMILY SSF46626 111 233 1.3E-35 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_27340 01ae5bae7e61a7d3de08f2d3fae2611a 634 Gene3D G3DSA:3.40.50.720 283 619 1.6E-108 T 14-10-2018 LH59_27340 01ae5bae7e61a7d3de08f2d3fae2611a 634 SUPERFAMILY SSF51735 285 540 2.53E-52 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_27340 01ae5bae7e61a7d3de08f2d3fae2611a 634 Pfam PF13727 CoA-binding domain 86 244 1.1E-11 T 14-10-2018 LH59_27340 01ae5bae7e61a7d3de08f2d3fae2611a 634 Gene3D G3DSA:3.40.50.720 149 268 4.0E-30 T 14-10-2018 LH59_27340 01ae5bae7e61a7d3de08f2d3fae2611a 634 SUPERFAMILY SSF53335 135 329 4.82E-17 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_27340 01ae5bae7e61a7d3de08f2d3fae2611a 634 Pfam PF02719 Polysaccharide biosynthesis protein 287 578 4.8E-120 T 14-10-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain LH59_11790 37469ee6549ae224c41dee6c247775bd 296 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 164 290 1.4E-35 T 14-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 LH59_11790 37469ee6549ae224c41dee6c247775bd 296 SUPERFAMILY SSF48179 162 292 4.53E-40 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 LH59_11790 37469ee6549ae224c41dee6c247775bd 296 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 6 19 - T 14-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 LH59_11790 37469ee6549ae224c41dee6c247775bd 296 TIGRFAM TIGR01692 HIBADH: 3-hydroxyisobutyrate dehydrogenase 6 291 2.4E-131 T 14-10-2018 IPR011548 3-hydroxyisobutyrate dehydrogenase GO:0008442|GO:0051287|GO:0055114 KEGG: 00280+1.1.1.31|Reactome: R-HSA-70895 LH59_11790 37469ee6549ae224c41dee6c247775bd 296 SUPERFAMILY SSF51735 3 162 2.82E-44 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_11790 37469ee6549ae224c41dee6c247775bd 296 Gene3D G3DSA:3.40.50.720 1 162 5.3E-54 T 14-10-2018 LH59_11790 37469ee6549ae224c41dee6c247775bd 296 PIRSF PIRSF000103 1 296 2.8E-79 T 14-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 LH59_11790 37469ee6549ae224c41dee6c247775bd 296 Gene3D G3DSA:1.10.1040.10 164 296 1.7E-45 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 LH59_11790 37469ee6549ae224c41dee6c247775bd 296 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 161 8.2E-51 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 LH59_01120 97f8f06ae1598db4b09f2c1eaa98a504 268 SUPERFAMILY SSF55811 103 263 6.09E-27 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 LH59_01120 97f8f06ae1598db4b09f2c1eaa98a504 268 Pfam PF00293 NUDIX domain 126 205 6.2E-10 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 LH59_01120 97f8f06ae1598db4b09f2c1eaa98a504 268 Gene3D G3DSA:3.90.79.10 117 263 5.0E-41 T 14-10-2018 LH59_01120 97f8f06ae1598db4b09f2c1eaa98a504 268 Gene3D G3DSA:3.30.750.160 27 202 5.0E-41 T 14-10-2018 LH59_17620 38bae3b3a14f8a8d887c028b29c7bd17 638 Gene3D G3DSA:3.40.50.300 270 538 3.0E-54 T 14-10-2018 LH59_17620 38bae3b3a14f8a8d887c028b29c7bd17 638 Gene3D G3DSA:3.40.50.300 2 269 9.1E-59 T 14-10-2018 LH59_17620 38bae3b3a14f8a8d887c028b29c7bd17 638 ProSitePatterns PS00211 ABC transporters family signature. 429 443 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_17620 38bae3b3a14f8a8d887c028b29c7bd17 638 SMART SM00382 335 502 3.1E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_17620 38bae3b3a14f8a8d887c028b29c7bd17 638 SMART SM00382 20 222 7.1E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_17620 38bae3b3a14f8a8d887c028b29c7bd17 638 Pfam PF12848 ABC transporter 210 285 3.9E-23 T 14-10-2018 IPR032781 ABC-transporter extension domain LH59_17620 38bae3b3a14f8a8d887c028b29c7bd17 638 SUPERFAMILY SSF52540 1 223 9.41E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_17620 38bae3b3a14f8a8d887c028b29c7bd17 638 Pfam PF00005 ABC transporter 326 457 6.1E-21 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_17620 38bae3b3a14f8a8d887c028b29c7bd17 638 SUPERFAMILY SSF52540 292 514 1.11E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_17620 38bae3b3a14f8a8d887c028b29c7bd17 638 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_17620 38bae3b3a14f8a8d887c028b29c7bd17 638 Pfam PF16326 ABC transporter C-terminal domain 565 627 9.7E-9 T 14-10-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 LH59_17620 38bae3b3a14f8a8d887c028b29c7bd17 638 Pfam PF00005 ABC transporter 11 171 5.6E-22 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_03075 5b5624c805bc280d6b8bf6314c3c0a23 405 Gene3D G3DSA:3.90.1150.10 31 397 2.7E-129 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_03075 5b5624c805bc280d6b8bf6314c3c0a23 405 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 241 254 - T 14-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 LH59_03075 5b5624c805bc280d6b8bf6314c3c0a23 405 Gene3D G3DSA:3.40.640.10 68 291 2.7E-129 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_03075 5b5624c805bc280d6b8bf6314c3c0a23 405 Pfam PF00155 Aminotransferase class I and II 37 397 8.7E-67 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LH59_03075 5b5624c805bc280d6b8bf6314c3c0a23 405 SUPERFAMILY SSF53383 9 403 4.49E-109 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_06360 d1ef7eae848540b174012fe675948679 211 TIGRFAM TIGR01083 nth: endonuclease III 5 194 9.4E-87 T 14-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 LH59_06360 d1ef7eae848540b174012fe675948679 211 ProSitePatterns PS01155 Endonuclease III family signature. 102 131 - T 14-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 LH59_06360 d1ef7eae848540b174012fe675948679 211 Gene3D G3DSA:1.10.1670.10 11 203 2.1E-78 T 14-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 LH59_06360 d1ef7eae848540b174012fe675948679 211 Hamap MF_00942 Endonuclease III [nth]. 1 209 38.065 T 14-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 LH59_06360 d1ef7eae848540b174012fe675948679 211 PIRSF PIRSF001435 1 210 4.7E-53 T 14-10-2018 LH59_06360 d1ef7eae848540b174012fe675948679 211 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 34 168 7.4E-21 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 LH59_06360 d1ef7eae848540b174012fe675948679 211 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 187 203 9.1E-5 T 14-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 LH59_06360 d1ef7eae848540b174012fe675948679 211 SUPERFAMILY SSF48150 3 208 2.04E-74 T 14-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 LH59_06360 d1ef7eae848540b174012fe675948679 211 SMART SM00478 38 185 7.4E-60 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 LH59_06360 d1ef7eae848540b174012fe675948679 211 Gene3D G3DSA:1.10.340.30 21 132 2.1E-78 T 14-10-2018 LH59_06360 d1ef7eae848540b174012fe675948679 211 Pfam PF00633 Helix-hairpin-helix motif 100 127 5.9E-9 T 14-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 LH59_06360 d1ef7eae848540b174012fe675948679 211 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 187 203 - T 14-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 LH59_06360 d1ef7eae848540b174012fe675948679 211 SMART SM00525 186 206 1.5E-4 T 14-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 LH59_26525 6fd3476fce77ad0cd4b29dfcd348b01d 413 SUPERFAMILY SSF53383 12 399 7.07E-90 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_26525 6fd3476fce77ad0cd4b29dfcd348b01d 413 Pfam PF00155 Aminotransferase class I and II 61 394 1.1E-39 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LH59_26525 6fd3476fce77ad0cd4b29dfcd348b01d 413 Gene3D G3DSA:3.90.1150.10 22 398 2.5E-117 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_26525 6fd3476fce77ad0cd4b29dfcd348b01d 413 Gene3D G3DSA:3.40.640.10 68 290 2.5E-117 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_15780 af734122e23509a721ec5213fa05ba4d 753 SMART SM00448 630 744 1.2E-31 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_15780 af734122e23509a721ec5213fa05ba4d 753 Pfam PF00072 Response regulator receiver domain 632 744 5.7E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_15780 af734122e23509a721ec5213fa05ba4d 753 Gene3D G3DSA:3.40.50.12740 629 753 1.9E-35 T 14-10-2018 LH59_15780 af734122e23509a721ec5213fa05ba4d 753 Pfam PF01584 CheW-like domain 477 604 4.8E-16 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 LH59_15780 af734122e23509a721ec5213fa05ba4d 753 Gene3D G3DSA:2.30.30.40 471 598 1.4E-25 T 14-10-2018 LH59_15780 af734122e23509a721ec5213fa05ba4d 753 SUPERFAMILY SSF52172 629 750 2.56E-32 T 14-10-2018 IPR011006 CheY-like superfamily LH59_15780 af734122e23509a721ec5213fa05ba4d 753 PRINTS PR00344 Bacterial sensor protein C-terminal signature 455 468 3.4E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_15780 af734122e23509a721ec5213fa05ba4d 753 PRINTS PR00344 Bacterial sensor protein C-terminal signature 431 449 3.4E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_15780 af734122e23509a721ec5213fa05ba4d 753 PRINTS PR00344 Bacterial sensor protein C-terminal signature 373 387 3.4E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_15780 af734122e23509a721ec5213fa05ba4d 753 SUPERFAMILY SSF47226 8 104 7.72E-23 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 LH59_15780 af734122e23509a721ec5213fa05ba4d 753 SMART SM00260 463 602 2.3E-7 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 LH59_15780 af734122e23509a721ec5213fa05ba4d 753 SUPERFAMILY SSF50341 470 602 7.72E-23 T 14-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 LH59_15780 af734122e23509a721ec5213fa05ba4d 753 SMART SM00387 328 471 1.1E-19 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_15780 af734122e23509a721ec5213fa05ba4d 753 Gene3D G3DSA:2.40.50.180 494 557 1.4E-25 T 14-10-2018 LH59_15780 af734122e23509a721ec5213fa05ba4d 753 Pfam PF01627 Hpt domain 11 102 2.2E-14 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 LH59_15780 af734122e23509a721ec5213fa05ba4d 753 SMART SM00073 8 105 2.1E-12 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 LH59_15780 af734122e23509a721ec5213fa05ba4d 753 Gene3D G3DSA:3.30.565.10 282 470 2.1E-49 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_15780 af734122e23509a721ec5213fa05ba4d 753 Gene3D G3DSA:1.20.120.160 3 127 4.1E-23 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 LH59_15780 af734122e23509a721ec5213fa05ba4d 753 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 332 470 4.0E-15 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_15780 af734122e23509a721ec5213fa05ba4d 753 SUPERFAMILY SSF55874 287 469 4.32E-36 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_00585 5e7ceb63dbe614ffa7e450a5ae72c0eb 323 SUPERFAMILY SSF53850 110 287 3.26E-11 T 14-10-2018 LH59_00585 5e7ceb63dbe614ffa7e450a5ae72c0eb 323 Gene3D G3DSA:3.40.190.150 28 312 5.4E-94 T 14-10-2018 LH59_00585 5e7ceb63dbe614ffa7e450a5ae72c0eb 323 Gene3D G3DSA:3.40.190.10 125 248 5.4E-94 T 14-10-2018 LH59_00585 5e7ceb63dbe614ffa7e450a5ae72c0eb 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 319 3.1E-70 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_00585 5e7ceb63dbe614ffa7e450a5ae72c0eb 323 PIRSF PIRSF017082 1 323 6.0E-76 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_16325 e7556bc6e14de671f04bda29ea494747 332 Gene3D G3DSA:3.50.30.50 71 332 4.4E-9 T 14-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 LH59_16325 e7556bc6e14de671f04bda29ea494747 332 Pfam PF04199 Putative cyclase 50 260 8.7E-14 T 14-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 LH59_16325 e7556bc6e14de671f04bda29ea494747 332 SUPERFAMILY SSF102198 94 331 4.05E-9 T 14-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 LH59_18565 cd96ea0630402b3c36538de24886497b 279 SUPERFAMILY SSF53850 40 279 4.83E-77 T 14-10-2018 LH59_18565 cd96ea0630402b3c36538de24886497b 279 Gene3D G3DSA:3.40.190.10 121 228 3.2E-88 T 14-10-2018 LH59_18565 cd96ea0630402b3c36538de24886497b 279 Gene3D G3DSA:3.40.190.10 40 276 3.2E-88 T 14-10-2018 LH59_18565 cd96ea0630402b3c36538de24886497b 279 TIGRFAM TIGR00363 TIGR00363: lipoprotein, YaeC family 34 276 1.1E-70 T 14-10-2018 IPR004872 Lipoprotein NlpA family LH59_18565 cd96ea0630402b3c36538de24886497b 279 Pfam PF03180 NLPA lipoprotein 40 279 5.9E-82 T 14-10-2018 IPR004872 Lipoprotein NlpA family LH59_18565 cd96ea0630402b3c36538de24886497b 279 PIRSF PIRSF002854 3 279 3.1E-90 T 14-10-2018 IPR004872 Lipoprotein NlpA family LH59_12610 32268e6fd59f32fde0fce468edb06d16 218 SUPERFAMILY SSF161098 13 201 3.01E-40 T 14-10-2018 IPR035906 MetI-like superfamily LH59_12610 32268e6fd59f32fde0fce468edb06d16 218 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 110 1.5E-30 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 LH59_12610 32268e6fd59f32fde0fce468edb06d16 218 Gene3D G3DSA:1.10.3720.10 1 217 1.0E-50 T 14-10-2018 IPR035906 MetI-like superfamily LH59_12610 32268e6fd59f32fde0fce468edb06d16 218 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 216 1.3E-18 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_19845 5a474152bd848a41e5772dcd9195cad9 569 Gene3D G3DSA:3.10.20.310 65 147 4.0E-14 T 14-10-2018 LH59_19845 5a474152bd848a41e5772dcd9195cad9 569 Pfam PF03865 Haemolysin secretion/activation protein ShlB/FhaC/HecB 241 529 1.8E-17 T 14-10-2018 IPR005565 Haemolysin activator HlyB, C-terminal LH59_19845 5a474152bd848a41e5772dcd9195cad9 569 Gene3D G3DSA:2.40.160.50 181 565 2.2E-59 T 14-10-2018 LH59_19845 5a474152bd848a41e5772dcd9195cad9 569 Pfam PF08479 POTRA domain, ShlB-type 75 147 1.0E-17 T 14-10-2018 IPR013686 Polypeptide-transport-associated, ShlB-type LH59_22920 447814d4bbd72573b266f8c331658518 523 Gene3D G3DSA:3.10.20.600 331 425 1.2E-20 T 14-10-2018 LH59_22920 447814d4bbd72573b266f8c331658518 523 Gene3D G3DSA:3.40.50.11540 152 330 5.9E-71 T 14-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_22920 447814d4bbd72573b266f8c331658518 523 SUPERFAMILY SSF142984 342 423 6.8E-19 T 14-10-2018 LH59_22920 447814d4bbd72573b266f8c331658518 523 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 149 318 1.5E-44 T 14-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_22920 447814d4bbd72573b266f8c331658518 523 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 441 452 - T 14-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_22920 447814d4bbd72573b266f8c331658518 523 SUPERFAMILY SSF140490 424 511 1.24E-28 T 14-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_22920 447814d4bbd72573b266f8c331658518 523 SUPERFAMILY SSF52833 6 86 4.03E-6 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_22920 447814d4bbd72573b266f8c331658518 523 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 430 511 7.8E-30 T 14-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_22920 447814d4bbd72573b266f8c331658518 523 SMART SM00928 428 474 7.8E-18 T 14-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_22920 447814d4bbd72573b266f8c331658518 523 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 266 281 - T 14-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_22920 447814d4bbd72573b266f8c331658518 523 Gene3D G3DSA:1.20.1440.230 426 521 9.9E-26 T 14-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_22920 447814d4bbd72573b266f8c331658518 523 SUPERFAMILY SSF142019 99 339 1.83E-86 T 14-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_13775 8e3910664bd3334d69630b6e8fc81900 209 Gene3D G3DSA:3.40.30.10 1 80 5.9E-22 T 14-10-2018 LH59_13775 8e3910664bd3334d69630b6e8fc81900 209 Pfam PF13410 Glutathione S-transferase, C-terminal domain 128 189 2.5E-7 T 14-10-2018 LH59_13775 8e3910664bd3334d69630b6e8fc81900 209 SUPERFAMILY SSF52833 4 77 4.57E-19 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_13775 8e3910664bd3334d69630b6e8fc81900 209 SUPERFAMILY SSF47616 76 204 8.49E-23 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily LH59_13775 8e3910664bd3334d69630b6e8fc81900 209 Pfam PF02798 Glutathione S-transferase, N-terminal domain 9 71 6.0E-14 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 LH59_13775 8e3910664bd3334d69630b6e8fc81900 209 Gene3D G3DSA:1.20.1050.10 81 203 1.4E-22 T 14-10-2018 LH59_07160 ee926e2cbf3c46ad228611d9ead97592 238 Pfam PF03473 MOSC domain 48 162 1.3E-26 T 14-10-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 LH59_07160 ee926e2cbf3c46ad228611d9ead97592 238 Pfam PF03475 3-alpha domain 172 211 2.6E-11 T 14-10-2018 IPR005163 3-alpha domain LH59_07160 ee926e2cbf3c46ad228611d9ead97592 238 SUPERFAMILY SSF50800 2 227 1.41E-78 T 14-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily LH59_07160 ee926e2cbf3c46ad228611d9ead97592 238 Gene3D G3DSA:2.40.33.20 2 234 4.4E-84 T 14-10-2018 LH59_11365 74d80635a2c1f80e353be2ec3c38ca24 384 TIGRFAM TIGR00328 flhB: flagellar biosynthetic protein FlhB 8 354 3.1E-125 T 14-10-2018 IPR006136 Flagellar biosynthetic protein FlhB GO:0015031|GO:0016021|GO:0044780 LH59_11365 74d80635a2c1f80e353be2ec3c38ca24 384 SUPERFAMILY SSF160544 244 351 1.83E-42 T 14-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal LH59_11365 74d80635a2c1f80e353be2ec3c38ca24 384 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 228 245 2.2E-38 T 14-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 LH59_11365 74d80635a2c1f80e353be2ec3c38ca24 384 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 10 32 2.2E-38 T 14-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 LH59_11365 74d80635a2c1f80e353be2ec3c38ca24 384 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 208 226 2.2E-38 T 14-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 LH59_11365 74d80635a2c1f80e353be2ec3c38ca24 384 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 302 323 2.2E-38 T 14-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 LH59_11365 74d80635a2c1f80e353be2ec3c38ca24 384 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 272 287 2.2E-38 T 14-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 LH59_11365 74d80635a2c1f80e353be2ec3c38ca24 384 Gene3D G3DSA:3.40.1690.10 217 356 1.0E-58 T 14-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal LH59_11365 74d80635a2c1f80e353be2ec3c38ca24 384 Pfam PF01312 FlhB HrpN YscU SpaS Family 8 347 1.9E-127 T 14-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 LH59_16705 72e763cee4f2581456db49d4e7508e88 402 Gene3D G3DSA:3.40.50.1100 61 391 1.8E-177 T 14-10-2018 LH59_16705 72e763cee4f2581456db49d4e7508e88 402 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 14 396 5.3E-183 T 14-10-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 LH59_16705 72e763cee4f2581456db49d4e7508e88 402 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 60 385 2.7E-50 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme LH59_16705 72e763cee4f2581456db49d4e7508e88 402 Gene3D G3DSA:3.40.50.1100 17 213 1.8E-177 T 14-10-2018 LH59_16705 72e763cee4f2581456db49d4e7508e88 402 PIRSF PIRSF001413 1 401 2.8E-161 T 14-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 LH59_16705 72e763cee4f2581456db49d4e7508e88 402 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 88 102 - T 14-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 LH59_16705 72e763cee4f2581456db49d4e7508e88 402 SUPERFAMILY SSF53686 10 395 6.02E-141 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme LH59_16705 72e763cee4f2581456db49d4e7508e88 402 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 9 398 50.806 T 14-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 LH59_26260 18514afc56c02f662f61675d912af0ec 335 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 95 2.0E-11 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 LH59_26260 18514afc56c02f662f61675d912af0ec 335 SUPERFAMILY SSF51735 118 262 1.03E-38 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_26260 18514afc56c02f662f61675d912af0ec 335 Gene3D G3DSA:3.90.180.10 9 326 5.0E-99 T 14-10-2018 LH59_26260 18514afc56c02f662f61675d912af0ec 335 Gene3D G3DSA:3.40.50.720 128 273 5.0E-99 T 14-10-2018 LH59_26260 18514afc56c02f662f61675d912af0ec 335 SUPERFAMILY SSF50129 2 154 3.5E-36 T 14-10-2018 IPR011032 GroES-like superfamily LH59_26260 18514afc56c02f662f61675d912af0ec 335 SMART SM00829 10 327 1.4E-25 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 LH59_26260 18514afc56c02f662f61675d912af0ec 335 Pfam PF00107 Zinc-binding dehydrogenase 157 253 9.6E-24 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 LH59_14200 eb120398c3f25af281015334b97d35fd 594 Pfam PF00571 CBS domain 450 501 1.1E-4 T 14-10-2018 IPR000644 CBS domain LH59_14200 eb120398c3f25af281015334b97d35fd 594 Gene3D G3DSA:3.10.580.10 441 575 2.1E-14 T 14-10-2018 LH59_14200 eb120398c3f25af281015334b97d35fd 594 SUPERFAMILY SSF54631 448 576 2.93E-17 T 14-10-2018 LH59_14200 eb120398c3f25af281015334b97d35fd 594 Pfam PF00654 Voltage gated chloride channel 82 416 3.6E-72 T 14-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 LH59_14200 eb120398c3f25af281015334b97d35fd 594 SUPERFAMILY SSF81340 17 438 1.27E-90 T 14-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 LH59_14200 eb120398c3f25af281015334b97d35fd 594 PRINTS PR00762 Chloride channel signature 124 143 2.0E-24 T 14-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 LH59_14200 eb120398c3f25af281015334b97d35fd 594 PRINTS PR00762 Chloride channel signature 338 358 2.0E-24 T 14-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 LH59_14200 eb120398c3f25af281015334b97d35fd 594 PRINTS PR00762 Chloride channel signature 385 404 2.0E-24 T 14-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 LH59_14200 eb120398c3f25af281015334b97d35fd 594 PRINTS PR00762 Chloride channel signature 175 194 2.0E-24 T 14-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 LH59_14200 eb120398c3f25af281015334b97d35fd 594 PRINTS PR00762 Chloride channel signature 367 383 2.0E-24 T 14-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 LH59_14200 eb120398c3f25af281015334b97d35fd 594 Gene3D G3DSA:1.10.3080.10 22 440 4.2E-86 T 14-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 LH59_14200 eb120398c3f25af281015334b97d35fd 594 SMART SM00116 457 507 11.0 T 14-10-2018 IPR000644 CBS domain LH59_14200 eb120398c3f25af281015334b97d35fd 594 SMART SM00116 524 573 0.79 T 14-10-2018 IPR000644 CBS domain LH59_05555 5d4b2992c4a77c4379daf7c89ebfab58 292 SUPERFAMILY SSF46785 1 109 2.42E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_05555 5d4b2992c4a77c4379daf7c89ebfab58 292 Gene3D G3DSA:3.40.190.10 165 262 6.7E-35 T 14-10-2018 LH59_05555 5d4b2992c4a77c4379daf7c89ebfab58 292 Pfam PF03466 LysR substrate binding domain 86 288 1.5E-39 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_05555 5d4b2992c4a77c4379daf7c89ebfab58 292 Gene3D G3DSA:1.10.10.10 1 85 1.0E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_05555 5d4b2992c4a77c4379daf7c89ebfab58 292 SUPERFAMILY SSF53850 88 289 8.69E-36 T 14-10-2018 LH59_05555 5d4b2992c4a77c4379daf7c89ebfab58 292 Gene3D G3DSA:3.40.190.10 90 274 6.7E-35 T 14-10-2018 LH59_05555 5d4b2992c4a77c4379daf7c89ebfab58 292 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 61 1.2E-13 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_24720 271aa678e4cef4b899073e796c8c9acf 424 SUPERFAMILY SSF48179 200 292 5.27E-25 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 LH59_24720 271aa678e4cef4b899073e796c8c9acf 424 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 7 180 6.9E-34 T 14-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 LH59_24720 271aa678e4cef4b899073e796c8c9acf 424 PIRSF PIRSF000124 6 421 4.5E-55 T 14-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 LH59_24720 271aa678e4cef4b899073e796c8c9acf 424 PIRSF PIRSF500136 1 424 3.2E-151 T 14-10-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 LH59_24720 271aa678e4cef4b899073e796c8c9acf 424 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 7 409 2.3E-120 T 14-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 LH59_24720 271aa678e4cef4b899073e796c8c9acf 424 SMART SM00984 317 417 1.3E-34 T 14-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 LH59_24720 271aa678e4cef4b899073e796c8c9acf 424 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 317 416 1.6E-19 T 14-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 LH59_24720 271aa678e4cef4b899073e796c8c9acf 424 SUPERFAMILY SSF52413 302 418 1.02E-28 T 14-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 LH59_24720 271aa678e4cef4b899073e796c8c9acf 424 Gene3D G3DSA:3.40.50.720 201 423 1.9E-55 T 14-10-2018 LH59_24720 271aa678e4cef4b899073e796c8c9acf 424 Gene3D G3DSA:3.40.50.720 2 198 2.7E-59 T 14-10-2018 LH59_24720 271aa678e4cef4b899073e796c8c9acf 424 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 202 290 4.0E-24 T 14-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 LH59_24720 271aa678e4cef4b899073e796c8c9acf 424 SUPERFAMILY SSF51735 7 191 8.18E-46 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_09185 f4a92544245ea7b705405b239375741d 451 SMART SM00382 3 146 0.92 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_09185 f4a92544245ea7b705405b239375741d 451 SMART SM00382 184 327 0.24 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_09185 f4a92544245ea7b705405b239375741d 451 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 75 93 1.4E-8 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 LH59_09185 f4a92544245ea7b705405b239375741d 451 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 7 27 1.4E-8 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 LH59_09185 f4a92544245ea7b705405b239375741d 451 Gene3D G3DSA:3.30.300.20 361 443 4.0E-21 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta LH59_09185 f4a92544245ea7b705405b239375741d 451 Hamap MF_00195 GTPase Der [der]. 4 444 37.997 T 14-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 LH59_09185 f4a92544245ea7b705405b239375741d 451 Pfam PF01926 50S ribosome-binding GTPase 188 305 1.8E-24 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 LH59_09185 f4a92544245ea7b705405b239375741d 451 Pfam PF01926 50S ribosome-binding GTPase 7 123 6.4E-24 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 LH59_09185 f4a92544245ea7b705405b239375741d 451 SUPERFAMILY SSF52540 141 447 2.99E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_09185 f4a92544245ea7b705405b239375741d 451 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 6 161 2.8E-17 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 LH59_09185 f4a92544245ea7b705405b239375741d 451 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 185 351 4.1E-25 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 LH59_09185 f4a92544245ea7b705405b239375741d 451 Gene3D G3DSA:3.40.50.300 181 356 2.7E-48 T 14-10-2018 LH59_09185 f4a92544245ea7b705405b239375741d 451 PIRSF PIRSF006485 3 449 4.3E-171 T 14-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 LH59_09185 f4a92544245ea7b705405b239375741d 451 Gene3D G3DSA:3.40.50.300 3 164 1.1E-39 T 14-10-2018 LH59_09185 f4a92544245ea7b705405b239375741d 451 SUPERFAMILY SSF52540 6 178 1.73E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_09185 f4a92544245ea7b705405b239375741d 451 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 5 441 1.4E-171 T 14-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 LH59_09185 f4a92544245ea7b705405b239375741d 451 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 361 441 2.0E-25 T 14-10-2018 IPR032859 GTPase Der, C-terminal KH-domain-like LH59_01205 0a732e3ad2a130155f1f6d9335af3118 440 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 320 423 8.9E-32 T 14-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 LH59_01205 0a732e3ad2a130155f1f6d9335af3118 440 Gene3D G3DSA:3.40.50.720 1 202 8.6E-82 T 14-10-2018 LH59_01205 0a732e3ad2a130155f1f6d9335af3118 440 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 204 296 2.2E-38 T 14-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 LH59_01205 0a732e3ad2a130155f1f6d9335af3118 440 PIRSF PIRSF500134 1 440 9.3E-193 T 14-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 LH59_01205 0a732e3ad2a130155f1f6d9335af3118 440 SUPERFAMILY SSF52413 305 434 1.44E-39 T 14-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 LH59_01205 0a732e3ad2a130155f1f6d9335af3118 440 PIRSF PIRSF000124 1 439 3.3E-149 T 14-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 LH59_01205 0a732e3ad2a130155f1f6d9335af3118 440 SUPERFAMILY SSF51735 1 194 1.21E-57 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_01205 0a732e3ad2a130155f1f6d9335af3118 440 Gene3D G3DSA:3.40.50.720 235 440 5.9E-81 T 14-10-2018 LH59_01205 0a732e3ad2a130155f1f6d9335af3118 440 Gene3D G3DSA:1.20.5.100 203 234 1.3E-18 T 14-10-2018 LH59_01205 0a732e3ad2a130155f1f6d9335af3118 440 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 185 1.6E-64 T 14-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 LH59_01205 0a732e3ad2a130155f1f6d9335af3118 440 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 420 1.4E-136 T 14-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 LH59_01205 0a732e3ad2a130155f1f6d9335af3118 440 SMART SM00984 320 424 3.1E-53 T 14-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 LH59_01205 0a732e3ad2a130155f1f6d9335af3118 440 SUPERFAMILY SSF48179 204 300 6.05E-34 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 LH59_10555 4b0ef4ca9b6b15b67b89a9844dd6cc3c 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 3.0E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_10555 4b0ef4ca9b6b15b67b89a9844dd6cc3c 302 SUPERFAMILY SSF53850 94 300 3.12E-45 T 14-10-2018 LH59_10555 4b0ef4ca9b6b15b67b89a9844dd6cc3c 302 Gene3D G3DSA:3.40.190.10 168 271 2.7E-44 T 14-10-2018 LH59_10555 4b0ef4ca9b6b15b67b89a9844dd6cc3c 302 Gene3D G3DSA:3.40.190.10 95 285 2.7E-44 T 14-10-2018 LH59_10555 4b0ef4ca9b6b15b67b89a9844dd6cc3c 302 SUPERFAMILY SSF46785 7 89 1.24E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_10555 4b0ef4ca9b6b15b67b89a9844dd6cc3c 302 Gene3D G3DSA:1.10.10.10 1 87 3.2E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_10555 4b0ef4ca9b6b15b67b89a9844dd6cc3c 302 Pfam PF03466 LysR substrate binding domain 92 297 3.2E-44 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_10555 4b0ef4ca9b6b15b67b89a9844dd6cc3c 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 3.4E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_10555 4b0ef4ca9b6b15b67b89a9844dd6cc3c 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 3.4E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_10555 4b0ef4ca9b6b15b67b89a9844dd6cc3c 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 3.4E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_27065 82f610f61a072b8d23f14e3e38c33161 346 Gene3D G3DSA:3.40.50.2000 172 316 9.9E-29 T 14-10-2018 LH59_27065 82f610f61a072b8d23f14e3e38c33161 346 Pfam PF13439 Glycosyltransferase Family 4 15 165 1.5E-17 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 LH59_27065 82f610f61a072b8d23f14e3e38c33161 346 SUPERFAMILY SSF53756 1 327 4.93E-64 T 14-10-2018 LH59_27065 82f610f61a072b8d23f14e3e38c33161 346 Pfam PF00534 Glycosyl transferases group 1 179 290 9.7E-21 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 LH59_27065 82f610f61a072b8d23f14e3e38c33161 346 Gene3D G3DSA:3.40.50.2000 1 171 8.8E-22 T 14-10-2018 LH59_10765 07c4cff118efecf4067b5e834976c2a5 390 PIRSF PIRSF000429 1 388 7.4E-67 T 14-10-2018 IPR002155 Thiolase GO:0016747 LH59_10765 07c4cff118efecf4067b5e834976c2a5 390 SUPERFAMILY SSF53901 16 359 1.87E-41 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_10765 07c4cff118efecf4067b5e834976c2a5 390 Pfam PF00108 Thiolase, N-terminal domain 6 228 9.7E-24 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 LH59_10765 07c4cff118efecf4067b5e834976c2a5 390 Gene3D G3DSA:3.40.47.10 3 388 3.6E-99 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_10765 07c4cff118efecf4067b5e834976c2a5 390 Pfam PF02803 Thiolase, C-terminal domain 262 365 1.7E-9 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 LH59_21945 f3f4c33c0c754ea1504fdc7c315f6944 539 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 325 481 4.9E-52 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 LH59_21945 f3f4c33c0c754ea1504fdc7c315f6944 539 Gene3D G3DSA:1.20.120.30 24 191 5.2E-8 T 14-10-2018 LH59_21945 f3f4c33c0c754ea1504fdc7c315f6944 539 Pfam PF00672 HAMP domain 215 261 5.0E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_21945 f3f4c33c0c754ea1504fdc7c315f6944 539 SMART SM00304 213 265 4.0E-11 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_21945 f3f4c33c0c754ea1504fdc7c315f6944 539 SUPERFAMILY SSF58104 233 518 4.45E-70 T 14-10-2018 LH59_21945 f3f4c33c0c754ea1504fdc7c315f6944 539 SMART SM00283 266 513 4.7E-85 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 LH59_21945 f3f4c33c0c754ea1504fdc7c315f6944 539 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 364 391 1.9E-62 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_21945 f3f4c33c0c754ea1504fdc7c315f6944 539 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 393 422 1.9E-62 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_21945 f3f4c33c0c754ea1504fdc7c315f6944 539 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 5 30 1.9E-62 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_21945 f3f4c33c0c754ea1504fdc7c315f6944 539 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 287 316 1.9E-62 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_21945 f3f4c33c0c754ea1504fdc7c315f6944 539 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 441 470 1.9E-62 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_21945 f3f4c33c0c754ea1504fdc7c315f6944 539 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 188 208 1.9E-62 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_21945 f3f4c33c0c754ea1504fdc7c315f6944 539 Pfam PF02203 Tar ligand binding domain homologue 1 150 2.4E-18 T 14-10-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 LH59_21945 f3f4c33c0c754ea1504fdc7c315f6944 539 Gene3D G3DSA:1.10.287.950 214 515 1.5E-86 T 14-10-2018 LH59_21945 f3f4c33c0c754ea1504fdc7c315f6944 539 SUPERFAMILY SSF47170 26 178 1.83E-18 T 14-10-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain superfamily LH59_28015 8ffe2eeb0f8afa6507c7c5665288ac32 396 PRINTS PR00315 GTP-binding elongation factor signature 94 105 8.3E-25 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_28015 8ffe2eeb0f8afa6507c7c5665288ac32 396 PRINTS PR00315 GTP-binding elongation factor signature 131 140 8.3E-25 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_28015 8ffe2eeb0f8afa6507c7c5665288ac32 396 PRINTS PR00315 GTP-binding elongation factor signature 58 66 8.3E-25 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_28015 8ffe2eeb0f8afa6507c7c5665288ac32 396 PRINTS PR00315 GTP-binding elongation factor signature 78 88 8.3E-25 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_28015 8ffe2eeb0f8afa6507c7c5665288ac32 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 8.3E-25 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_28015 8ffe2eeb0f8afa6507c7c5665288ac32 396 SUPERFAMILY SSF50447 207 303 1.96E-30 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily LH59_28015 8ffe2eeb0f8afa6507c7c5665288ac32 396 Pfam PF03144 Elongation factor Tu domain 2 227 295 5.3E-17 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 LH59_28015 8ffe2eeb0f8afa6507c7c5665288ac32 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 396 1.8E-226 T 14-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 LH59_28015 8ffe2eeb0f8afa6507c7c5665288ac32 396 SUPERFAMILY SSF50465 304 396 9.5E-36 T 14-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal LH59_28015 8ffe2eeb0f8afa6507c7c5665288ac32 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 2.1E-58 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_28015 8ffe2eeb0f8afa6507c7c5665288ac32 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 60.227 T 14-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 LH59_28015 8ffe2eeb0f8afa6507c7c5665288ac32 396 Gene3D G3DSA:2.40.30.10 208 336 2.2E-51 T 14-10-2018 LH59_28015 8ffe2eeb0f8afa6507c7c5665288ac32 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site LH59_28015 8ffe2eeb0f8afa6507c7c5665288ac32 396 Gene3D G3DSA:3.40.50.300 1 205 1.3E-70 T 14-10-2018 LH59_28015 8ffe2eeb0f8afa6507c7c5665288ac32 396 SUPERFAMILY SSF52540 5 221 2.17E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_28015 8ffe2eeb0f8afa6507c7c5665288ac32 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 1.5E-32 T 14-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal LH59_28015 8ffe2eeb0f8afa6507c7c5665288ac32 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 149 3.2E-15 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 LH59_28015 8ffe2eeb0f8afa6507c7c5665288ac32 396 Gene3D G3DSA:2.40.30.10 340 395 3.3E-28 T 14-10-2018 LH59_19590 ee8ea071931b553ef6c5c2b15bf04815 532 PIRSF PIRSF000137 1 532 2.1E-141 T 14-10-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 LH59_19590 ee8ea071931b553ef6c5c2b15bf04815 532 Pfam PF05199 GMC oxidoreductase 385 520 3.3E-40 T 14-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 LH59_19590 ee8ea071931b553ef6c5c2b15bf04815 532 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 81 104 - T 14-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 LH59_19590 ee8ea071931b553ef6c5c2b15bf04815 532 SUPERFAMILY SSF51905 3 529 3.72E-77 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_19590 ee8ea071931b553ef6c5c2b15bf04815 532 Gene3D G3DSA:1.10.1220.110 96 148 9.8E-167 T 14-10-2018 LH59_19590 ee8ea071931b553ef6c5c2b15bf04815 532 Pfam PF00732 GMC oxidoreductase 4 293 3.4E-78 T 14-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 LH59_19590 ee8ea071931b553ef6c5c2b15bf04815 532 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 252 266 - T 14-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 LH59_19590 ee8ea071931b553ef6c5c2b15bf04815 532 Gene3D G3DSA:3.50.50.60 4 525 9.8E-167 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_19590 ee8ea071931b553ef6c5c2b15bf04815 532 SUPERFAMILY SSF54373 288 471 3.34E-54 T 14-10-2018 LH59_19590 ee8ea071931b553ef6c5c2b15bf04815 532 Gene3D G3DSA:4.10.450.10 37 194 9.8E-167 T 14-10-2018 IPR027424 Glucose Oxidase, domain 2 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|Reactome: R-HSA-6798163 LH59_19590 ee8ea071931b553ef6c5c2b15bf04815 532 Gene3D G3DSA:3.30.410.40 149 468 9.8E-167 T 14-10-2018 LH59_21790 84a902a14193b77613a0f0ebdf5e4ec5 348 Pfam PF00248 Aldo/keto reductase family 15 319 2.2E-80 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain LH59_21790 84a902a14193b77613a0f0ebdf5e4ec5 348 Gene3D G3DSA:3.20.20.100 1 343 5.4E-128 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily LH59_21790 84a902a14193b77613a0f0ebdf5e4ec5 348 SUPERFAMILY SSF51430 1 319 3.14E-103 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily LH59_21160 36ab10d762cc79961de34eabae70f2f5 274 Gene3D G3DSA:3.30.1130.10 137 274 5.1E-59 T 14-10-2018 LH59_21160 36ab10d762cc79961de34eabae70f2f5 274 Pfam PF14819 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term 14 122 6.2E-46 T 14-10-2018 IPR029139 NADPH-dependent 7-cyano-7-deazaguanine reductase, N-terminal KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 LH59_21160 36ab10d762cc79961de34eabae70f2f5 274 PIRSF PIRSF004750 1 274 4.2E-123 T 14-10-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 LH59_21160 36ab10d762cc79961de34eabae70f2f5 274 SUPERFAMILY SSF55620 178 257 1.33E-11 T 14-10-2018 LH59_21160 36ab10d762cc79961de34eabae70f2f5 274 TIGRFAM TIGR03138 QueF: queuine synthase 2 274 2.4E-126 T 14-10-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 LH59_21160 36ab10d762cc79961de34eabae70f2f5 274 Hamap MF_00817 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 274 150.633 T 14-10-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 LH59_21160 36ab10d762cc79961de34eabae70f2f5 274 Gene3D G3DSA:3.30.1130.10 14 131 4.5E-42 T 14-10-2018 LH59_21160 36ab10d762cc79961de34eabae70f2f5 274 Pfam PF14489 QueF-like protein 187 262 3.7E-28 T 14-10-2018 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 LH59_22745 9b3563db11d4a241582387107fc64103 311 SUPERFAMILY SSF82866 73 294 1.44E-39 T 14-10-2018 LH59_22745 9b3563db11d4a241582387107fc64103 311 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 38 283 1.8E-75 T 14-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 LH59_22745 9b3563db11d4a241582387107fc64103 311 Pfam PF07549 SecD/SecF GG Motif 32 59 2.3E-8 T 14-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site LH59_22745 9b3563db11d4a241582387107fc64103 311 Gene3D G3DSA:1.20.1640.10 95 302 1.4E-12 T 14-10-2018 LH59_22745 9b3563db11d4a241582387107fc64103 311 PRINTS PR01755 Bacterial translocase SecF protein signature 199 217 5.1E-27 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial LH59_22745 9b3563db11d4a241582387107fc64103 311 PRINTS PR01755 Bacterial translocase SecF protein signature 37 52 5.1E-27 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial LH59_22745 9b3563db11d4a241582387107fc64103 311 PRINTS PR01755 Bacterial translocase SecF protein signature 151 165 5.1E-27 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial LH59_22745 9b3563db11d4a241582387107fc64103 311 PRINTS PR01755 Bacterial translocase SecF protein signature 231 246 5.1E-27 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial LH59_22745 9b3563db11d4a241582387107fc64103 311 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 10 294 29.198 T 14-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 LH59_22745 9b3563db11d4a241582387107fc64103 311 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 95 280 2.0E-49 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial LH59_22745 9b3563db11d4a241582387107fc64103 311 Pfam PF02355 Protein export membrane protein 107 291 1.7E-63 T 14-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial LH59_16850 090a77a2fb4b4cd3e4afef264f060a54 597 Pfam PF00515 Tetratricopeptide repeat 112 144 3.3E-10 T 14-10-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 LH59_16850 090a77a2fb4b4cd3e4afef264f060a54 597 Pfam PF13432 Tetratricopeptide repeat 151 194 0.002 T 14-10-2018 LH59_16850 090a77a2fb4b4cd3e4afef264f060a54 597 SUPERFAMILY SSF48452 208 304 2.46E-11 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_16850 090a77a2fb4b4cd3e4afef264f060a54 597 Gene3D G3DSA:1.25.40.10 153 195 7.3E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_16850 090a77a2fb4b4cd3e4afef264f060a54 597 Gene3D G3DSA:1.25.40.10 120 152 1.5E-11 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_16850 090a77a2fb4b4cd3e4afef264f060a54 597 Pfam PF07721 Tetratricopeptide repeat 44 68 3.8E-4 T 14-10-2018 IPR011717 Tetratricopeptide TPR-4 GO:0042802 LH59_16850 090a77a2fb4b4cd3e4afef264f060a54 597 SMART SM00028 213 246 290.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 LH59_16850 090a77a2fb4b4cd3e4afef264f060a54 597 SMART SM00028 145 178 0.0024 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 LH59_16850 090a77a2fb4b4cd3e4afef264f060a54 597 SMART SM00028 111 144 1.9E-8 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 LH59_16850 090a77a2fb4b4cd3e4afef264f060a54 597 SMART SM00028 77 110 0.012 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 LH59_16850 090a77a2fb4b4cd3e4afef264f060a54 597 SMART SM00028 247 280 95.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 LH59_16850 090a77a2fb4b4cd3e4afef264f060a54 597 SMART SM00028 43 76 0.0041 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 LH59_16850 090a77a2fb4b4cd3e4afef264f060a54 597 Pfam PF14559 Tetratricopeptide repeat 223 279 3.7E-7 T 14-10-2018 LH59_16850 090a77a2fb4b4cd3e4afef264f060a54 597 SUPERFAMILY SSF48452 6 183 3.03E-34 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_16850 090a77a2fb4b4cd3e4afef264f060a54 597 Gene3D G3DSA:1.25.40.10 1 119 2.0E-22 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_16850 090a77a2fb4b4cd3e4afef264f060a54 597 SUPERFAMILY SSF53756 335 575 3.11E-25 T 14-10-2018 LH59_16850 090a77a2fb4b4cd3e4afef264f060a54 597 Gene3D G3DSA:3.40.50.2000 441 587 1.5E-7 T 14-10-2018 LH59_16850 090a77a2fb4b4cd3e4afef264f060a54 597 Gene3D G3DSA:1.25.40.10 206 319 2.1E-11 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_00475 f52a7adbc3d917fdc9473983e786bc83 463 Pfam PF07690 Major Facilitator Superfamily 30 421 7.3E-48 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_00475 f52a7adbc3d917fdc9473983e786bc83 463 Gene3D G3DSA:1.20.1720.10 27 240 5.3E-45 T 14-10-2018 LH59_00475 f52a7adbc3d917fdc9473983e786bc83 463 SUPERFAMILY SSF103473 17 457 2.49E-61 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_00475 f52a7adbc3d917fdc9473983e786bc83 463 Gene3D G3DSA:1.20.1250.20 271 463 1.8E-17 T 14-10-2018 LH59_23540 eaad44efb040fac3302437ee96837637 297 SUPERFAMILY SSF46785 5 66 1.9E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_23540 eaad44efb040fac3302437ee96837637 297 Gene3D G3DSA:1.20.120.530 152 292 4.2E-21 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_23540 eaad44efb040fac3302437ee96837637 297 SMART SM00345 7 65 2.6E-9 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_23540 eaad44efb040fac3302437ee96837637 297 Gene3D G3DSA:1.10.10.10 1 65 5.5E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_23540 eaad44efb040fac3302437ee96837637 297 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 64 3.0E-11 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_23540 eaad44efb040fac3302437ee96837637 297 SUPERFAMILY SSF48008 153 289 1.28E-21 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_23540 eaad44efb040fac3302437ee96837637 297 Pfam PF07729 FCD domain 159 282 1.7E-18 T 14-10-2018 IPR011711 GntR, C-terminal LH59_23540 eaad44efb040fac3302437ee96837637 297 SMART SM00895 158 283 4.4E-12 T 14-10-2018 IPR011711 GntR, C-terminal LH59_23250 e4273460bbecb3e9816c755b17407db7 468 PIRSF PIRSF006060 9 466 2.3E-63 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 LH59_23250 e4273460bbecb3e9816c755b17407db7 468 ProSitePatterns PS00218 Amino acid permeases signature. 50 80 - T 14-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 LH59_23250 e4273460bbecb3e9816c755b17407db7 468 Gene3D G3DSA:1.20.1740.10 16 467 2.5E-60 T 14-10-2018 LH59_23250 e4273460bbecb3e9816c755b17407db7 468 Pfam PF00324 Amino acid permease 26 453 8.1E-92 T 14-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 LH59_12570 a9757b5162e93f7dffa87ebe1c0703fa 324 Gene3D G3DSA:3.40.190.170 24 324 3.4E-111 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily LH59_12570 a9757b5162e93f7dffa87ebe1c0703fa 324 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 33 292 1.1E-41 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 LH59_12570 a9757b5162e93f7dffa87ebe1c0703fa 324 SUPERFAMILY SSF53850 106 282 1.81E-6 T 14-10-2018 LH59_26450 138289d5786b5ff1456b29358724e797 210 PIRSF PIRSF006324 1 207 1.7E-51 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 LH59_26450 138289d5786b5ff1456b29358724e797 210 Pfam PF01810 LysE type translocator 15 204 3.2E-32 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 LH59_21565 561a64a1e653d234d2901a39827731b1 314 Gene3D G3DSA:3.40.50.720 6 192 9.0E-54 T 14-10-2018 LH59_21565 561a64a1e653d234d2901a39827731b1 314 SUPERFAMILY SSF48179 192 284 1.02E-13 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 LH59_21565 561a64a1e653d234d2901a39827731b1 314 PIRSF PIRSF000105 5 265 9.4E-67 T 14-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 LH59_21565 561a64a1e653d234d2901a39827731b1 314 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 192 256 9.4E-13 T 14-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 LH59_21565 561a64a1e653d234d2901a39827731b1 314 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 13 188 4.8E-48 T 14-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 LH59_21565 561a64a1e653d234d2901a39827731b1 314 SUPERFAMILY SSF51735 10 189 2.75E-48 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_21565 561a64a1e653d234d2901a39827731b1 314 Gene3D G3DSA:1.10.1040.10 193 314 2.6E-33 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 LH59_01510 826e9b13a5c04076fe176428888e3e89 107 Gene3D G3DSA:1.10.760.10 40 99 1.7E-22 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_01510 826e9b13a5c04076fe176428888e3e89 107 SUPERFAMILY SSF46626 46 99 2.16E-9 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_23565 f140bcf1c46241fdd97f8e54e7e7f184 335 Gene3D G3DSA:2.60.120.1440 114 231 1.1E-22 T 14-10-2018 LH59_23565 f140bcf1c46241fdd97f8e54e7e7f184 335 Pfam PF16220 Domain of unknown function (DUF4880) 18 58 4.2E-7 T 14-10-2018 IPR032623 FecR, N-terminal LH59_23565 f140bcf1c46241fdd97f8e54e7e7f184 335 Pfam PF16344 Domain of unknown function (DUF4974) 246 310 3.8E-7 T 14-10-2018 IPR032508 Protein FecR, C-terminal LH59_23565 f140bcf1c46241fdd97f8e54e7e7f184 335 PIRSF PIRSF018266 6 329 4.5E-75 T 14-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component LH59_23565 f140bcf1c46241fdd97f8e54e7e7f184 335 Pfam PF04773 FecR protein 125 213 8.5E-19 T 14-10-2018 IPR006860 FecR protein LH59_23495 72ce2f34aab3fd4d7f73a04ec57d7d17 127 SUPERFAMILY SSF54593 7 126 1.34E-21 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_23495 72ce2f34aab3fd4d7f73a04ec57d7d17 127 Gene3D G3DSA:3.10.180.10 3 127 7.6E-30 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_23495 72ce2f34aab3fd4d7f73a04ec57d7d17 127 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 121 2.1E-7 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain LH59_24645 bd79ea2e64bd12b671f8f565f21b2b0b 261 SUPERFAMILY SSF48317 18 230 9.16E-14 T 14-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily LH59_24645 bd79ea2e64bd12b671f8f565f21b2b0b 261 Gene3D G3DSA:1.20.144.10 17 237 5.4E-8 T 14-10-2018 LH59_24645 bd79ea2e64bd12b671f8f565f21b2b0b 261 SMART SM00014 104 229 0.0043 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase LH59_24645 bd79ea2e64bd12b671f8f565f21b2b0b 261 Pfam PF01569 PAP2 superfamily 106 230 2.1E-14 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase LH59_19265 14fd3d46719196f2ec44bee4c80c069c 134 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3 126 4.7E-7 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain LH59_19265 14fd3d46719196f2ec44bee4c80c069c 134 Gene3D G3DSA:3.10.180.10 1 131 3.8E-36 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_19265 14fd3d46719196f2ec44bee4c80c069c 134 SUPERFAMILY SSF54593 2 132 3.58E-22 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_04890 1579ebe11d51aa98e81deba1c9c5d5b4 523 SUPERFAMILY SSF53850 17 505 8.32E-123 T 14-10-2018 LH59_04890 1579ebe11d51aa98e81deba1c9c5d5b4 523 Gene3D G3DSA:3.40.190.10 30 275 6.5E-114 T 14-10-2018 LH59_04890 1579ebe11d51aa98e81deba1c9c5d5b4 523 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 65 435 1.0E-82 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain LH59_04890 1579ebe11d51aa98e81deba1c9c5d5b4 523 Gene3D G3DSA:3.10.105.10 276 503 6.5E-114 T 14-10-2018 LH59_04890 1579ebe11d51aa98e81deba1c9c5d5b4 523 Gene3D G3DSA:3.90.76.10 56 164 6.5E-114 T 14-10-2018 LH59_04890 1579ebe11d51aa98e81deba1c9c5d5b4 523 PIRSF PIRSF002741 8 520 3.9E-87 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 LH59_15170 ea4294daa004e48b008c6875c035848f 444 Gene3D G3DSA:1.20.1250.20 9 430 1.1E-54 T 14-10-2018 LH59_15170 ea4294daa004e48b008c6875c035848f 444 Pfam PF07690 Major Facilitator Superfamily 253 423 1.9E-13 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_15170 ea4294daa004e48b008c6875c035848f 444 Pfam PF00083 Sugar (and other) transporter 14 224 1.5E-20 T 14-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 LH59_15170 ea4294daa004e48b008c6875c035848f 444 SUPERFAMILY SSF103473 4 424 9.55E-61 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_24870 90fcef51eeaf6777456923ffec576a27 283 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 120 5.5E-9 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain LH59_24870 90fcef51eeaf6777456923ffec576a27 283 Gene3D G3DSA:3.40.630.30 139 276 4.6E-20 T 14-10-2018 LH59_24870 90fcef51eeaf6777456923ffec576a27 283 Gene3D G3DSA:3.10.180.10 2 126 4.8E-23 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_24870 90fcef51eeaf6777456923ffec576a27 283 SUPERFAMILY SSF54593 5 125 1.88E-24 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_24870 90fcef51eeaf6777456923ffec576a27 283 SUPERFAMILY SSF55729 141 269 2.57E-21 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_24870 90fcef51eeaf6777456923ffec576a27 283 Pfam PF13508 Acetyltransferase (GNAT) domain 183 264 3.5E-9 T 14-10-2018 IPR000182 GNAT domain LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2050 2351 2.1E-108 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 Pfam PF08659 KR domain 3223 3401 2.5E-67 T 14-10-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 Gene3D G3DSA:3.30.300.30 920 985 6.5E-11 T 14-10-2018 LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 Gene3D G3DSA:3.40.50.150 1005 1184 3.5E-25 T 14-10-2018 LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 SUPERFAMILY SSF47336 1420 1493 8.64E-19 T 14-10-2018 IPR036736 ACP-like superfamily LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 SUPERFAMILY SSF50129 2910 3037 1.73E-29 T 14-10-2018 IPR011032 GroES-like superfamily LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 Gene3D G3DSA:3.40.50.12230 1 264 9.0E-47 T 14-10-2018 LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 Pfam PF13649 Methyltransferase domain 1038 1115 1.2E-6 T 14-10-2018 LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 Gene3D G3DSA:3.30.70.3290 1960 2399 2.2E-150 T 14-10-2018 LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 Gene3D G3DSA:3.40.50.720 3217 3470 9.7E-76 T 14-10-2018 LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 TIGRFAM TIGR01746 Thioester-redct: thioester reductase domain 3639 3954 1.1E-65 T 14-10-2018 IPR010080 Thioester reductase-like domain LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3223 3403 1.7E-66 T 14-10-2018 LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 SUPERFAMILY SSF51735 2703 2886 1.8E-32 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 ProSitePatterns PS00455 Putative AMP-binding domain signature. 676 687 - T 14-10-2018 IPR020845 AMP-binding, conserved site LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 Gene3D G3DSA:3.40.366.10 2048 2354 2.2E-150 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 Gene3D G3DSA:3.40.50.11460 2706 2885 7.7E-26 T 14-10-2018 LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 SMART SM00825 Beta-ketoacyl synthase 1514 1941 7.5E-215 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 SMART SM01294 3512 3579 4.3E-4 T 14-10-2018 LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 SUPERFAMILY SSF53335 1008 1141 1.3E-16 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 Pfam PF14765 Polyketide synthase dehydratase 2416 2696 6.2E-56 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 Pfam PF00501 AMP-binding enzyme 534 925 1.7E-100 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 SUPERFAMILY SSF52777 285 497 1.89E-6 T 14-10-2018 LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 Pfam PF02911 Formyl transferase, C-terminal domain 157 251 4.2E-7 T 14-10-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 Gene3D G3DSA:3.30.300.30 1342 1417 7.0E-14 T 14-10-2018 LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 Gene3D G3DSA:3.90.180.10 2889 3212 2.6E-111 T 14-10-2018 LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 Gene3D G3DSA:3.10.129.110 2406 2700 4.7E-69 T 14-10-2018 LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 SUPERFAMILY SSF51735 3638 3904 1.55E-29 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 Pfam PF00698 Acyl transferase domain 2050 2369 2.1E-53 T 14-10-2018 IPR014043 Acyl transferase LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 Pfam PF00551 Formyl transferase 24 115 3.4E-7 T 14-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1771 1888 1.9E-42 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 Gene3D G3DSA:1.10.1200.10 3491 3584 7.3E-24 T 14-10-2018 IPR036736 ACP-like superfamily LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 Pfam PF07993 Male sterility protein 3641 3869 2.8E-51 T 14-10-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 SUPERFAMILY SSF53901 1509 1937 4.85E-100 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 Pfam PF13602 Zinc-binding dehydrogenase 3083 3210 1.5E-19 T 14-10-2018 LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 SMART SM00823 Phosphopantetheine attachment site 3511 3583 5.3E-21 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 SMART SM00823 Phosphopantetheine attachment site 1427 1496 1.7E-6 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 Gene3D G3DSA:3.30.559.30 284 520 6.4E-9 T 14-10-2018 LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 SUPERFAMILY SSF56801 495 1439 5.89E-151 T 14-10-2018 LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 SUPERFAMILY SSF52151 2046 2343 4.19E-69 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 SUPERFAMILY SSF47336 3505 3595 8.11E-16 T 14-10-2018 IPR036736 ACP-like superfamily LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 Gene3D G3DSA:3.40.50.720 3623 3988 2.9E-70 T 14-10-2018 LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 SMART SM00829 2907 3210 3.3E-156 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 SMART SM00826 2416 2577 1.3E-46 T 14-10-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 Gene3D G3DSA:3.40.50.12780 522 919 1.2E-130 T 14-10-2018 LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 Gene3D G3DSA:3.40.47.10 1504 1959 1.3E-188 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 Pfam PF00550 Phosphopantetheine attachment site 1428 1492 1.3E-11 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 Pfam PF00550 Phosphopantetheine attachment site 3513 3579 3.3E-10 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 SUPERFAMILY SSF51735 3220 3459 1.9E-48 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 Gene3D G3DSA:1.10.1200.10 1419 1500 2.2E-23 T 14-10-2018 IPR036736 ACP-like superfamily LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 SUPERFAMILY SSF55048 2176 2242 6.41E-12 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 SUPERFAMILY SSF51735 3004 3181 1.6E-38 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 SUPERFAMILY SSF50486 157 264 4.51E-10 T 14-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 SUPERFAMILY SSF53328 1 152 2.62E-24 T 14-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1891 2004 9.4E-15 T 14-10-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1512 1763 4.5E-86 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3538 3553 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site LH59_18790 11a95b87d58397b8b2dcfcf8d7769f1c 4005 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 555 949 8.5E-129 T 14-10-2018 IPR010071 Amino acid adenylation domain LH59_21875 f0a4efe973dcbf2978ded5b4b5aef590 258 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 12 258 1.6E-121 T 14-10-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 LH59_21875 f0a4efe973dcbf2978ded5b4b5aef590 258 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_21875 f0a4efe973dcbf2978ded5b4b5aef590 258 Gene3D G3DSA:3.40.50.300 10 256 4.7E-66 T 14-10-2018 LH59_21875 f0a4efe973dcbf2978ded5b4b5aef590 258 SMART SM00382 36 230 4.7E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_21875 f0a4efe973dcbf2978ded5b4b5aef590 258 Pfam PF00005 ABC transporter 28 182 5.7E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_21875 f0a4efe973dcbf2978ded5b4b5aef590 258 SUPERFAMILY SSF52540 11 244 5.44E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_23605 e2a1294e69cdac4959bcf0da1a182a16 354 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 185 352 2.1E-47 T 14-10-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 LH59_23605 e2a1294e69cdac4959bcf0da1a182a16 354 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 137 157 8.0E-27 T 14-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 LH59_23605 e2a1294e69cdac4959bcf0da1a182a16 354 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 173 189 8.0E-27 T 14-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 LH59_23605 e2a1294e69cdac4959bcf0da1a182a16 354 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 194 205 8.0E-27 T 14-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 LH59_23605 e2a1294e69cdac4959bcf0da1a182a16 354 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 275 291 8.0E-27 T 14-10-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 LH59_23605 e2a1294e69cdac4959bcf0da1a182a16 354 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 75 181 1.4E-28 T 14-10-2018 IPR013856 Peptidase M4 domain GO:0004222 LH59_23605 e2a1294e69cdac4959bcf0da1a182a16 354 Gene3D G3DSA:1.10.390.10 187 353 1.7E-64 T 14-10-2018 IPR027268 Peptidase M4/M1, CTD superfamily LH59_23605 e2a1294e69cdac4959bcf0da1a182a16 354 Gene3D G3DSA:3.10.170.10 7 186 2.7E-63 T 14-10-2018 LH59_23605 e2a1294e69cdac4959bcf0da1a182a16 354 SUPERFAMILY SSF55486 75 352 9.16E-80 T 14-10-2018 LH59_06110 6d4e59443bb09c0b4a325d793c117bd3 158 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 118 134 - T 14-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06110 6d4e59443bb09c0b4a325d793c117bd3 158 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 1 151 41.224 T 14-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06110 6d4e59443bb09c0b4a325d793c117bd3 158 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 37 145 2.8E-22 T 14-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06110 6d4e59443bb09c0b4a325d793c117bd3 158 SUPERFAMILY SSF56770 9 151 1.31E-65 T 14-10-2018 LH59_06110 6d4e59443bb09c0b4a325d793c117bd3 158 Gene3D G3DSA:3.40.50.12280 2 158 1.8E-77 T 14-10-2018 LH59_06110 6d4e59443bb09c0b4a325d793c117bd3 158 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 11 151 2.0E-75 T 14-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_26855 4d53fdae83c39ff20504080f9e201c14 658 Gene3D G3DSA:3.40.50.12780 11 327 7.5E-52 T 14-10-2018 LH59_26855 4d53fdae83c39ff20504080f9e201c14 658 ProSitePatterns PS00455 Putative AMP-binding domain signature. 197 208 - T 14-10-2018 IPR020845 AMP-binding, conserved site LH59_26855 4d53fdae83c39ff20504080f9e201c14 658 Pfam PF00501 AMP-binding enzyme 25 482 3.2E-92 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 LH59_26855 4d53fdae83c39ff20504080f9e201c14 658 SUPERFAMILY SSF56801 11 614 5.76E-112 T 14-10-2018 LH59_26855 4d53fdae83c39ff20504080f9e201c14 658 Gene3D G3DSA:3.40.50.12780 328 475 2.1E-34 T 14-10-2018 LH59_26395 141fc6cae4f456b53c26b56824499fa3 331 Gene3D G3DSA:3.40.190.10 132 256 2.0E-101 T 14-10-2018 LH59_26395 141fc6cae4f456b53c26b56824499fa3 331 SUPERFAMILY SSF53850 122 292 6.08E-10 T 14-10-2018 LH59_26395 141fc6cae4f456b53c26b56824499fa3 331 Gene3D G3DSA:3.40.190.150 33 321 2.0E-101 T 14-10-2018 LH59_26395 141fc6cae4f456b53c26b56824499fa3 331 PIRSF PIRSF017082 1 331 9.1E-75 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_26395 141fc6cae4f456b53c26b56824499fa3 331 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 328 4.5E-72 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_14225 66c4659f8cd06e88cd32cdd96815f73f 162 Gene3D G3DSA:3.30.450.150 11 156 3.9E-39 T 14-10-2018 IPR038084 GlcG-like domain superfamily LH59_14225 66c4659f8cd06e88cd32cdd96815f73f 162 SUPERFAMILY SSF143744 23 155 3.79E-35 T 14-10-2018 IPR038084 GlcG-like domain superfamily LH59_14225 66c4659f8cd06e88cd32cdd96815f73f 162 Pfam PF03928 Haem-degrading 30 153 3.0E-28 T 14-10-2018 IPR005624 Haem-degrading LH59_11720 d4941c568b02e8ad5cb33560d49c98e9 262 Gene3D G3DSA:3.30.1330.30 2 101 1.2E-6 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like LH59_11720 d4941c568b02e8ad5cb33560d49c98e9 262 Pfam PF00588 SpoU rRNA Methylase family 113 250 2.0E-29 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 LH59_11720 d4941c568b02e8ad5cb33560d49c98e9 262 SUPERFAMILY SSF55315 2 101 8.0E-11 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like LH59_11720 d4941c568b02e8ad5cb33560d49c98e9 262 Gene3D G3DSA:3.40.1280.10 109 260 3.2E-41 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal LH59_11720 d4941c568b02e8ad5cb33560d49c98e9 262 SUPERFAMILY SSF75217 111 257 5.17E-36 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases LH59_27635 ac00801d153ea83cb5fb3d118ef14c72 953 Gene3D G3DSA:1.20.1580.10 91 500 8.2E-244 T 14-10-2018 LH59_27635 ac00801d153ea83cb5fb3d118ef14c72 953 Gene3D G3DSA:1.20.1580.10 700 837 9.4E-141 T 14-10-2018 LH59_27635 ac00801d153ea83cb5fb3d118ef14c72 953 Gene3D G3DSA:3.30.190.20 131 243 8.2E-244 T 14-10-2018 LH59_27635 ac00801d153ea83cb5fb3d118ef14c72 953 Gene3D G3DSA:3.40.50.300 7 602 8.2E-244 T 14-10-2018 LH59_27635 ac00801d153ea83cb5fb3d118ef14c72 953 SUPERFAMILY SSF52540 622 928 8.54E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_27635 ac00801d153ea83cb5fb3d118ef14c72 953 Gene3D G3DSA:3.40.50.300 622 943 9.4E-141 T 14-10-2018 LH59_27635 ac00801d153ea83cb5fb3d118ef14c72 953 Hamap MF_00205 UvrABC system protein A [uvrA]. 2 947 22.159 T 14-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 LH59_27635 ac00801d153ea83cb5fb3d118ef14c72 953 ProSitePatterns PS00211 ABC transporters family signature. 837 851 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_27635 ac00801d153ea83cb5fb3d118ef14c72 953 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 5 932 0.0 T 14-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 LH59_27635 ac00801d153ea83cb5fb3d118ef14c72 953 ProSitePatterns PS00211 ABC transporters family signature. 495 509 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_27635 ac00801d153ea83cb5fb3d118ef14c72 953 SUPERFAMILY SSF52540 5 577 1.46E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_27635 ac00801d153ea83cb5fb3d118ef14c72 953 Gene3D G3DSA:1.10.8.280 286 402 8.2E-244 T 14-10-2018 LH59_20835 bc38e1efb31b40a0040afdc1e76e93ce 809 SMART SM00965 85 136 5.9E-14 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 LH59_20835 bc38e1efb31b40a0040afdc1e76e93ce 809 Gene3D G3DSA:2.170.130.10 152 287 1.1E-35 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily LH59_20835 bc38e1efb31b40a0040afdc1e76e93ce 809 Pfam PF07660 Secretin and TonB N terminus short domain 86 135 5.6E-8 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 LH59_20835 bc38e1efb31b40a0040afdc1e76e93ce 809 Gene3D G3DSA:2.40.170.20 288 809 2.1E-137 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_20835 bc38e1efb31b40a0040afdc1e76e93ce 809 Gene3D G3DSA:3.55.50.30 63 135 2.2E-25 T 14-10-2018 LH59_20835 bc38e1efb31b40a0040afdc1e76e93ce 809 Pfam PF07715 TonB-dependent Receptor Plug Domain 178 278 5.9E-21 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_20835 bc38e1efb31b40a0040afdc1e76e93ce 809 SUPERFAMILY SSF56935 139 809 2.24E-135 T 14-10-2018 LH59_20835 bc38e1efb31b40a0040afdc1e76e93ce 809 Pfam PF00593 TonB dependent receptor 386 808 2.5E-63 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_20835 bc38e1efb31b40a0040afdc1e76e93ce 809 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 178 808 4.4E-108 T 14-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 LH59_27590 0dd008706516f132dd1b861ff0ca8ab2 284 SUPERFAMILY SSF52499 6 275 4.32E-12 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 LH59_27590 0dd008706516f132dd1b861ff0ca8ab2 284 Gene3D G3DSA:3.40.50.850 6 273 7.8E-42 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 LH59_07295 0ac3bbe4aaf1cc616ac5957f834fd5b4 570 Pfam PF00575 S1 RNA binding domain 199 269 1.6E-23 T 14-10-2018 IPR003029 S1 domain GO:0003676 LH59_07295 0ac3bbe4aaf1cc616ac5957f834fd5b4 570 Pfam PF00575 S1 RNA binding domain 28 94 4.8E-6 T 14-10-2018 IPR003029 S1 domain GO:0003676 LH59_07295 0ac3bbe4aaf1cc616ac5957f834fd5b4 570 Pfam PF00575 S1 RNA binding domain 371 443 4.6E-18 T 14-10-2018 IPR003029 S1 domain GO:0003676 LH59_07295 0ac3bbe4aaf1cc616ac5957f834fd5b4 570 Pfam PF00575 S1 RNA binding domain 112 180 3.5E-12 T 14-10-2018 IPR003029 S1 domain GO:0003676 LH59_07295 0ac3bbe4aaf1cc616ac5957f834fd5b4 570 Pfam PF00575 S1 RNA binding domain 458 529 3.5E-14 T 14-10-2018 IPR003029 S1 domain GO:0003676 LH59_07295 0ac3bbe4aaf1cc616ac5957f834fd5b4 570 Pfam PF00575 S1 RNA binding domain 285 356 1.3E-20 T 14-10-2018 IPR003029 S1 domain GO:0003676 LH59_07295 0ac3bbe4aaf1cc616ac5957f834fd5b4 570 Gene3D G3DSA:2.40.50.140 367 452 2.3E-25 T 14-10-2018 LH59_07295 0ac3bbe4aaf1cc616ac5957f834fd5b4 570 Gene3D G3DSA:2.40.50.140 107 190 1.4E-9 T 14-10-2018 LH59_07295 0ac3bbe4aaf1cc616ac5957f834fd5b4 570 Gene3D G3DSA:2.40.50.140 277 366 2.9E-28 T 14-10-2018 LH59_07295 0ac3bbe4aaf1cc616ac5957f834fd5b4 570 SUPERFAMILY SSF50249 13 122 7.46E-19 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_07295 0ac3bbe4aaf1cc616ac5957f834fd5b4 570 Gene3D G3DSA:2.40.50.140 15 106 1.5E-15 T 14-10-2018 LH59_07295 0ac3bbe4aaf1cc616ac5957f834fd5b4 570 Gene3D G3DSA:2.40.50.140 196 276 1.1E-28 T 14-10-2018 LH59_07295 0ac3bbe4aaf1cc616ac5957f834fd5b4 570 PRINTS PR00681 Ribosomal protein S1 signature 164 184 4.8E-81 T 14-10-2018 LH59_07295 0ac3bbe4aaf1cc616ac5957f834fd5b4 570 PRINTS PR00681 Ribosomal protein S1 signature 117 133 4.8E-81 T 14-10-2018 LH59_07295 0ac3bbe4aaf1cc616ac5957f834fd5b4 570 PRINTS PR00681 Ribosomal protein S1 signature 93 112 4.8E-81 T 14-10-2018 LH59_07295 0ac3bbe4aaf1cc616ac5957f834fd5b4 570 PRINTS PR00681 Ribosomal protein S1 signature 221 242 4.8E-81 T 14-10-2018 LH59_07295 0ac3bbe4aaf1cc616ac5957f834fd5b4 570 PRINTS PR00681 Ribosomal protein S1 signature 30 48 4.8E-81 T 14-10-2018 LH59_07295 0ac3bbe4aaf1cc616ac5957f834fd5b4 570 PRINTS PR00681 Ribosomal protein S1 signature 339 357 4.8E-81 T 14-10-2018 LH59_07295 0ac3bbe4aaf1cc616ac5957f834fd5b4 570 PRINTS PR00681 Ribosomal protein S1 signature 135 152 4.8E-81 T 14-10-2018 LH59_07295 0ac3bbe4aaf1cc616ac5957f834fd5b4 570 PRINTS PR00681 Ribosomal protein S1 signature 48 62 4.8E-81 T 14-10-2018 LH59_07295 0ac3bbe4aaf1cc616ac5957f834fd5b4 570 PRINTS PR00681 Ribosomal protein S1 signature 299 318 4.8E-81 T 14-10-2018 LH59_07295 0ac3bbe4aaf1cc616ac5957f834fd5b4 570 SUPERFAMILY SSF50249 199 286 1.29E-26 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_07295 0ac3bbe4aaf1cc616ac5957f834fd5b4 570 Gene3D G3DSA:2.40.50.140 453 536 9.4E-19 T 14-10-2018 LH59_07295 0ac3bbe4aaf1cc616ac5957f834fd5b4 570 PIRSF PIRSF002111 1 543 1.3E-213 T 14-10-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 LH59_07295 0ac3bbe4aaf1cc616ac5957f834fd5b4 570 TIGRFAM TIGR00717 rpsA: ribosomal protein bS1 12 529 5.0E-206 T 14-10-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 LH59_07295 0ac3bbe4aaf1cc616ac5957f834fd5b4 570 SUPERFAMILY SSF50249 264 365 7.31E-26 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_07295 0ac3bbe4aaf1cc616ac5957f834fd5b4 570 SUPERFAMILY SSF50249 355 446 3.66E-22 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_07295 0ac3bbe4aaf1cc616ac5957f834fd5b4 570 SUPERFAMILY SSF50249 438 540 3.28E-20 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_07295 0ac3bbe4aaf1cc616ac5957f834fd5b4 570 SUPERFAMILY SSF50249 112 194 7.17E-16 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_07295 0ac3bbe4aaf1cc616ac5957f834fd5b4 570 SMART SM00316 371 443 2.0E-21 T 14-10-2018 IPR022967 RNA-binding domain, S1 LH59_07295 0ac3bbe4aaf1cc616ac5957f834fd5b4 570 SMART SM00316 112 180 2.6E-10 T 14-10-2018 IPR022967 RNA-binding domain, S1 LH59_07295 0ac3bbe4aaf1cc616ac5957f834fd5b4 570 SMART SM00316 284 356 4.2E-24 T 14-10-2018 IPR022967 RNA-binding domain, S1 LH59_07295 0ac3bbe4aaf1cc616ac5957f834fd5b4 570 SMART SM00316 28 96 0.0041 T 14-10-2018 IPR022967 RNA-binding domain, S1 LH59_07295 0ac3bbe4aaf1cc616ac5957f834fd5b4 570 SMART SM00316 199 269 1.9E-29 T 14-10-2018 IPR022967 RNA-binding domain, S1 LH59_07295 0ac3bbe4aaf1cc616ac5957f834fd5b4 570 SMART SM00316 458 529 1.7E-15 T 14-10-2018 IPR022967 RNA-binding domain, S1 LH59_03740 ca0cc974413b57b27bc7de1f7174f193 477 SUPERFAMILY SSF46785 16 87 1.68E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_03740 ca0cc974413b57b27bc7de1f7174f193 477 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 57 2.0E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_03740 ca0cc974413b57b27bc7de1f7174f193 477 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 57 73 2.0E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_03740 ca0cc974413b57b27bc7de1f7174f193 477 Gene3D G3DSA:3.40.640.10 160 377 1.5E-81 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_03740 ca0cc974413b57b27bc7de1f7174f193 477 Gene3D G3DSA:1.10.10.10 14 85 3.9E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_03740 ca0cc974413b57b27bc7de1f7174f193 477 SMART SM00345 24 83 3.7E-19 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_03740 ca0cc974413b57b27bc7de1f7174f193 477 Pfam PF00155 Aminotransferase class I and II 146 465 6.9E-35 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LH59_03740 ca0cc974413b57b27bc7de1f7174f193 477 SUPERFAMILY SSF53383 127 465 7.43E-79 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_03740 ca0cc974413b57b27bc7de1f7174f193 477 Pfam PF00392 Bacterial regulatory proteins, gntR family 22 83 1.1E-16 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_03740 ca0cc974413b57b27bc7de1f7174f193 477 Gene3D G3DSA:3.90.1150.10 130 466 1.5E-81 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_28160 2a09dcbca06046918d1390926c10e6a0 470 SUPERFAMILY SSF55874 303 453 1.44E-28 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_28160 2a09dcbca06046918d1390926c10e6a0 470 Pfam PF08521 Two-component sensor kinase N-terminal 9 154 5.9E-33 T 14-10-2018 IPR013727 Two-component sensor kinase, N-terminal LH59_28160 2a09dcbca06046918d1390926c10e6a0 470 Pfam PF00512 His Kinase A (phospho-acceptor) domain 233 294 9.8E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_28160 2a09dcbca06046918d1390926c10e6a0 470 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 351 438 2.7E-13 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_28160 2a09dcbca06046918d1390926c10e6a0 470 Gene3D G3DSA:3.30.565.10 305 460 1.2E-26 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_28160 2a09dcbca06046918d1390926c10e6a0 470 PRINTS PR00344 Bacterial sensor protein C-terminal signature 416 434 8.5E-5 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_28160 2a09dcbca06046918d1390926c10e6a0 470 PRINTS PR00344 Bacterial sensor protein C-terminal signature 383 397 8.5E-5 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_28160 2a09dcbca06046918d1390926c10e6a0 470 SUPERFAMILY SSF47384 215 295 8.44E-13 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 LH59_28160 2a09dcbca06046918d1390926c10e6a0 470 SMART SM00388 232 297 2.2E-10 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_28160 2a09dcbca06046918d1390926c10e6a0 470 SMART SM00387 346 457 2.2E-21 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_28160 2a09dcbca06046918d1390926c10e6a0 470 Gene3D G3DSA:1.10.287.130 183 298 4.3E-15 T 14-10-2018 LH59_08175 61c6935278d518b367bafcc5280dd8a3 367 SUPERFAMILY SSF55103 199 365 4.74E-15 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 LH59_08175 61c6935278d518b367bafcc5280dd8a3 367 Gene3D G3DSA:3.30.465.40 6 188 1.3E-34 T 14-10-2018 LH59_08175 61c6935278d518b367bafcc5280dd8a3 367 SUPERFAMILY SSF56176 7 177 5.14E-35 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 LH59_08175 61c6935278d518b367bafcc5280dd8a3 367 Pfam PF01565 FAD binding domain 9 139 1.7E-22 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 LH59_23745 7df6fe399498c11f84ec79f413920003 262 Pfam PF12833 Helix-turn-helix domain 181 256 3.2E-21 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_23745 7df6fe399498c11f84ec79f413920003 262 Gene3D G3DSA:2.60.120.10 20 113 2.4E-5 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_23745 7df6fe399498c11f84ec79f413920003 262 SMART SM00342 173 255 8.0E-22 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_23745 7df6fe399498c11f84ec79f413920003 262 Pfam PF02311 AraC-like ligand binding domain 26 139 5.9E-11 T 14-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 LH59_23745 7df6fe399498c11f84ec79f413920003 262 SUPERFAMILY SSF46689 210 256 2.55E-7 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_23745 7df6fe399498c11f84ec79f413920003 262 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 210 251 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 LH59_23745 7df6fe399498c11f84ec79f413920003 262 Gene3D G3DSA:1.10.10.60 157 260 2.7E-20 T 14-10-2018 LH59_23745 7df6fe399498c11f84ec79f413920003 262 SUPERFAMILY SSF51182 30 182 3.82E-18 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_21070 336dbce9f9659a8ad4fb2287293f39e8 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 52 1.4E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_21070 336dbce9f9659a8ad4fb2287293f39e8 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 42 1.4E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_21070 336dbce9f9659a8ad4fb2287293f39e8 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 52 63 1.4E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_21070 336dbce9f9659a8ad4fb2287293f39e8 308 Gene3D G3DSA:3.40.190.10 108 297 5.6E-39 T 14-10-2018 LH59_21070 336dbce9f9659a8ad4fb2287293f39e8 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 16 75 4.5E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_21070 336dbce9f9659a8ad4fb2287293f39e8 308 Gene3D G3DSA:3.40.190.10 178 280 5.6E-39 T 14-10-2018 LH59_21070 336dbce9f9659a8ad4fb2287293f39e8 308 Pfam PF03466 LysR substrate binding domain 102 306 9.7E-39 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_21070 336dbce9f9659a8ad4fb2287293f39e8 308 Gene3D G3DSA:1.10.10.10 13 101 5.6E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_21070 336dbce9f9659a8ad4fb2287293f39e8 308 SUPERFAMILY SSF53850 102 306 7.91E-39 T 14-10-2018 LH59_21070 336dbce9f9659a8ad4fb2287293f39e8 308 SUPERFAMILY SSF46785 13 123 9.38E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_09580 f4f5b9172457c3f5e6a34e811850f618 244 Gene3D G3DSA:1.20.120.530 100 235 2.7E-27 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_09580 f4f5b9172457c3f5e6a34e811850f618 244 SUPERFAMILY SSF46785 10 79 1.88E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_09580 f4f5b9172457c3f5e6a34e811850f618 244 Pfam PF07729 FCD domain 101 222 1.6E-25 T 14-10-2018 IPR011711 GntR, C-terminal LH59_09580 f4f5b9172457c3f5e6a34e811850f618 244 SMART SM00345 16 75 2.7E-21 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_09580 f4f5b9172457c3f5e6a34e811850f618 244 SUPERFAMILY SSF48008 100 231 3.4E-26 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_09580 f4f5b9172457c3f5e6a34e811850f618 244 Gene3D G3DSA:1.10.10.10 7 81 5.6E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_09580 f4f5b9172457c3f5e6a34e811850f618 244 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 75 3.3E-20 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_09580 f4f5b9172457c3f5e6a34e811850f618 244 SMART SM00895 101 224 3.3E-23 T 14-10-2018 IPR011711 GntR, C-terminal LH59_09580 f4f5b9172457c3f5e6a34e811850f618 244 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 65 3.8E-11 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_09580 f4f5b9172457c3f5e6a34e811850f618 244 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 49 3.8E-11 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_00980 0ccfc75ee3ced37661b06d710bf81cec 81 Pfam PF01722 BolA-like protein 23 75 1.2E-20 T 14-10-2018 IPR002634 BolA protein LH59_00980 0ccfc75ee3ced37661b06d710bf81cec 81 SUPERFAMILY SSF82657 2 80 2.49E-29 T 14-10-2018 IPR036065 BolA-like superfamily LH59_00980 0ccfc75ee3ced37661b06d710bf81cec 81 PIRSF PIRSF003113 1 81 3.9E-24 T 14-10-2018 IPR002634 BolA protein LH59_00980 0ccfc75ee3ced37661b06d710bf81cec 81 Gene3D G3DSA:3.30.300.90 4 75 2.5E-29 T 14-10-2018 LH59_20900 884083b32a210cd037fecadfbd76b4df 441 Gene3D G3DSA:1.10.287.130 183 289 1.5E-16 T 14-10-2018 LH59_20900 884083b32a210cd037fecadfbd76b4df 441 SMART SM00387 330 441 3.4E-26 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_20900 884083b32a210cd037fecadfbd76b4df 441 Pfam PF00672 HAMP domain 179 227 1.4E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_20900 884083b32a210cd037fecadfbd76b4df 441 SUPERFAMILY SSF47384 218 286 2.94E-8 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 LH59_20900 884083b32a210cd037fecadfbd76b4df 441 SMART SM00304 179 231 5.1E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_20900 884083b32a210cd037fecadfbd76b4df 441 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 332 436 7.7E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_20900 884083b32a210cd037fecadfbd76b4df 441 SUPERFAMILY SSF55874 287 437 4.58E-32 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_20900 884083b32a210cd037fecadfbd76b4df 441 Gene3D G3DSA:3.30.565.10 293 438 8.3E-28 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_20900 884083b32a210cd037fecadfbd76b4df 441 PRINTS PR00344 Bacterial sensor protein C-terminal signature 366 380 9.5E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_20900 884083b32a210cd037fecadfbd76b4df 441 PRINTS PR00344 Bacterial sensor protein C-terminal signature 401 419 9.5E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_20900 884083b32a210cd037fecadfbd76b4df 441 PRINTS PR00344 Bacterial sensor protein C-terminal signature 384 394 9.5E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_20900 884083b32a210cd037fecadfbd76b4df 441 SMART SM00388 232 290 0.0021 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_21350 7ef518d66a2fa18357d110097559b01b 393 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 391 6.0E-139 T 14-10-2018 IPR002155 Thiolase GO:0016747 LH59_21350 7ef518d66a2fa18357d110097559b01b 393 SUPERFAMILY SSF53901 4 269 7.27E-82 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_21350 7ef518d66a2fa18357d110097559b01b 393 Pfam PF00108 Thiolase, N-terminal domain 4 262 3.3E-91 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 LH59_21350 7ef518d66a2fa18357d110097559b01b 393 Gene3D G3DSA:3.40.47.10 7 276 7.1E-151 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_21350 7ef518d66a2fa18357d110097559b01b 393 ProSitePatterns PS00099 Thiolases active site. 374 387 - T 14-10-2018 IPR020610 Thiolase, active site GO:0016747 LH59_21350 7ef518d66a2fa18357d110097559b01b 393 Gene3D G3DSA:3.40.47.10 127 389 7.1E-151 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_21350 7ef518d66a2fa18357d110097559b01b 393 Pfam PF02803 Thiolase, C-terminal domain 271 392 2.0E-45 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 LH59_21350 7ef518d66a2fa18357d110097559b01b 393 SUPERFAMILY SSF53901 271 392 4.22E-43 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_21350 7ef518d66a2fa18357d110097559b01b 393 PIRSF PIRSF000429 1 393 5.2E-127 T 14-10-2018 IPR002155 Thiolase GO:0016747 LH59_21350 7ef518d66a2fa18357d110097559b01b 393 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 85 103 - T 14-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 LH59_23410 72bc0398ededa9fcba5abc80fa1818f9 451 PIRSF PIRSF006603 1 445 2.5E-70 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 LH59_23410 72bc0398ededa9fcba5abc80fa1818f9 451 TIGRFAM TIGR00797 matE: MATE efflux family protein 16 395 1.8E-44 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 LH59_23410 72bc0398ededa9fcba5abc80fa1818f9 451 Pfam PF01554 MatE 246 396 6.9E-20 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 LH59_23410 72bc0398ededa9fcba5abc80fa1818f9 451 Pfam PF01554 MatE 16 174 1.8E-19 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 LH59_04855 449e1c9827b8de7b346a411b4229e254 543 Gene3D G3DSA:3.30.300.30 414 522 5.8E-25 T 14-10-2018 LH59_04855 449e1c9827b8de7b346a411b4229e254 543 SUPERFAMILY SSF56801 4 521 1.31E-109 T 14-10-2018 LH59_04855 449e1c9827b8de7b346a411b4229e254 543 Pfam PF13193 AMP-binding enzyme C-terminal domain 429 510 1.9E-15 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain LH59_04855 449e1c9827b8de7b346a411b4229e254 543 Pfam PF00501 AMP-binding enzyme 35 420 1.0E-68 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 LH59_04855 449e1c9827b8de7b346a411b4229e254 543 ProSitePatterns PS00455 Putative AMP-binding domain signature. 165 176 - T 14-10-2018 IPR020845 AMP-binding, conserved site LH59_04855 449e1c9827b8de7b346a411b4229e254 543 Gene3D G3DSA:3.40.50.12780 4 413 4.6E-78 T 14-10-2018 LH59_07035 593ac40a9973955d60301fe0611f982d 791 Gene3D G3DSA:1.10.150.310 518 649 1.7E-49 T 14-10-2018 LH59_07035 593ac40a9973955d60301fe0611f982d 791 Gene3D G3DSA:1.10.3500.10 126 517 2.5E-149 T 14-10-2018 IPR023323 Tex-like domain superfamily LH59_07035 593ac40a9973955d60301fe0611f982d 791 Pfam PF12836 Helix-hairpin-helix motif 510 574 7.6E-27 T 14-10-2018 LH59_07035 593ac40a9973955d60301fe0611f982d 791 SUPERFAMILY SSF47781 489 577 1.78E-28 T 14-10-2018 IPR010994 RuvA domain 2-like LH59_07035 593ac40a9973955d60301fe0611f982d 791 Pfam PF00575 S1 RNA binding domain 670 739 6.6E-22 T 14-10-2018 IPR003029 S1 domain GO:0003676 LH59_07035 593ac40a9973955d60301fe0611f982d 791 SUPERFAMILY SSF53098 340 488 2.88E-52 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily LH59_07035 593ac40a9973955d60301fe0611f982d 791 SUPERFAMILY SSF50249 657 744 2.61E-24 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_07035 593ac40a9973955d60301fe0611f982d 791 SMART SM00316 668 739 1.3E-24 T 14-10-2018 IPR022967 RNA-binding domain, S1 LH59_07035 593ac40a9973955d60301fe0611f982d 791 SUPERFAMILY SSF47781 579 651 6.67E-19 T 14-10-2018 IPR010994 RuvA domain 2-like LH59_07035 593ac40a9973955d60301fe0611f982d 791 Gene3D G3DSA:2.40.50.140 650 744 4.6E-29 T 14-10-2018 LH59_07035 593ac40a9973955d60301fe0611f982d 791 SMART SM00732 344 443 9.1E-39 T 14-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 LH59_07035 593ac40a9973955d60301fe0611f982d 791 Gene3D G3DSA:3.30.420.140 343 470 2.5E-149 T 14-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 LH59_07035 593ac40a9973955d60301fe0611f982d 791 Gene3D G3DSA:1.10.10.650 14 123 5.4E-39 T 14-10-2018 IPR023319 Tex-like protein, HTH domain superfamily LH59_07035 593ac40a9973955d60301fe0611f982d 791 Pfam PF09371 Tex-like protein N-terminal domain 23 206 2.1E-67 T 14-10-2018 IPR018974 Tex-like protein, N-terminal LH59_07035 593ac40a9973955d60301fe0611f982d 791 SUPERFAMILY SSF158832 17 339 1.83E-110 T 14-10-2018 LH59_07035 593ac40a9973955d60301fe0611f982d 791 Pfam PF16921 Tex protein YqgF-like domain 344 470 7.6E-53 T 14-10-2018 IPR032639 Tex protein, YqgF-like domain LH59_16210 c8bcdb1b46c21ed83d1874a3a3dc87c3 321 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 1.1E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_16210 c8bcdb1b46c21ed83d1874a3a3dc87c3 321 SUPERFAMILY SSF46785 1 85 1.21E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_16210 c8bcdb1b46c21ed83d1874a3a3dc87c3 321 SUPERFAMILY SSF53850 88 286 2.09E-29 T 14-10-2018 LH59_16210 c8bcdb1b46c21ed83d1874a3a3dc87c3 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.7E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_16210 c8bcdb1b46c21ed83d1874a3a3dc87c3 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.7E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_16210 c8bcdb1b46c21ed83d1874a3a3dc87c3 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.7E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_16210 c8bcdb1b46c21ed83d1874a3a3dc87c3 321 Gene3D G3DSA:1.10.10.10 1 92 5.1E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_16210 c8bcdb1b46c21ed83d1874a3a3dc87c3 321 Gene3D G3DSA:3.40.190.290 93 291 8.1E-26 T 14-10-2018 LH59_16210 c8bcdb1b46c21ed83d1874a3a3dc87c3 321 Pfam PF03466 LysR substrate binding domain 88 287 2.8E-27 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_05600 d30f0e4f103cac61911643e23f30d915 588 Pfam PF00005 ABC transporter 352 501 8.9E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_05600 d30f0e4f103cac61911643e23f30d915 588 SUPERFAMILY SSF52540 328 569 8.4E-83 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_05600 d30f0e4f103cac61911643e23f30d915 588 Gene3D G3DSA:3.40.50.300 331 578 8.7E-86 T 14-10-2018 LH59_05600 d30f0e4f103cac61911643e23f30d915 588 Pfam PF00664 ABC transporter transmembrane region 53 261 2.1E-14 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 LH59_05600 d30f0e4f103cac61911643e23f30d915 588 SMART SM00382 361 547 4.6E-19 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_05600 d30f0e4f103cac61911643e23f30d915 588 Gene3D G3DSA:1.20.1560.10 1 321 1.1E-27 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 LH59_05600 d30f0e4f103cac61911643e23f30d915 588 SUPERFAMILY SSF90123 4 327 7.32E-35 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 LH59_05600 d30f0e4f103cac61911643e23f30d915 588 ProSitePatterns PS00211 ABC transporters family signature. 473 487 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_11625 a656444e715e17d69df246d8fcc5ff59 161 Pfam PF02600 Disulfide bond formation protein DsbB 7 151 5.8E-29 T 14-10-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 LH59_11625 a656444e715e17d69df246d8fcc5ff59 161 SUPERFAMILY SSF158442 10 151 1.11E-25 T 14-10-2018 IPR023380 DsbB-like superfamily LH59_11625 a656444e715e17d69df246d8fcc5ff59 161 Gene3D G3DSA:1.20.1550.10 1 158 3.2E-24 T 14-10-2018 IPR023380 DsbB-like superfamily LH59_05940 7cea241be83def6ababd5aeeda05bc58 718 Gene3D G3DSA:2.40.170.20 183 718 1.2E-112 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_05940 7cea241be83def6ababd5aeeda05bc58 718 Gene3D G3DSA:2.170.130.10 55 179 2.5E-28 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily LH59_05940 7cea241be83def6ababd5aeeda05bc58 718 SUPERFAMILY SSF56935 41 716 1.83E-108 T 14-10-2018 LH59_05940 7cea241be83def6ababd5aeeda05bc58 718 Pfam PF00593 TonB dependent receptor 260 715 5.2E-58 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_05940 7cea241be83def6ababd5aeeda05bc58 718 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 59 716 3.8E-94 T 14-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 LH59_05940 7cea241be83def6ababd5aeeda05bc58 718 Pfam PF07715 TonB-dependent Receptor Plug Domain 59 170 1.9E-18 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_27925 9e07cf79b7bce63359d4d746522b00ad 700 Gene3D G3DSA:3.30.70.870 438 488 2.8E-26 T 14-10-2018 LH59_27925 9e07cf79b7bce63359d4d746522b00ad 700 SUPERFAMILY SSF52540 6 288 2.28E-105 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_27925 9e07cf79b7bce63359d4d746522b00ad 700 Pfam PF00009 Elongation factor Tu GTP binding domain 9 288 9.8E-65 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_27925 9e07cf79b7bce63359d4d746522b00ad 700 Gene3D G3DSA:2.40.30.10 294 421 8.1E-52 T 14-10-2018 LH59_27925 9e07cf79b7bce63359d4d746522b00ad 700 Gene3D G3DSA:3.40.50.300 1 293 5.0E-113 T 14-10-2018 LH59_27925 9e07cf79b7bce63359d4d746522b00ad 700 Pfam PF00679 Elongation factor G C-terminus 606 693 1.1E-31 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like LH59_27925 9e07cf79b7bce63359d4d746522b00ad 700 Pfam PF03764 Elongation factor G, domain IV 484 604 4.9E-49 T 14-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 LH59_27925 9e07cf79b7bce63359d4d746522b00ad 700 SMART SM00889 485 604 5.3E-75 T 14-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 LH59_27925 9e07cf79b7bce63359d4d746522b00ad 700 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 699 0.0 T 14-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 LH59_27925 9e07cf79b7bce63359d4d746522b00ad 700 SUPERFAMILY SSF50447 271 409 3.31E-37 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily LH59_27925 9e07cf79b7bce63359d4d746522b00ad 700 Hamap MF_00054_B Elongation factor G [fusA]. 6 698 112.234 T 14-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 LH59_27925 9e07cf79b7bce63359d4d746522b00ad 700 SMART SM00838 606 694 2.5E-56 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like LH59_27925 9e07cf79b7bce63359d4d746522b00ad 700 Pfam PF14492 Elongation Factor G, domain II 409 483 7.7E-34 T 14-10-2018 LH59_27925 9e07cf79b7bce63359d4d746522b00ad 700 SUPERFAMILY SSF54211 484 605 5.82E-45 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold LH59_27925 9e07cf79b7bce63359d4d746522b00ad 700 Pfam PF03144 Elongation factor Tu domain 2 329 396 2.9E-19 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 LH59_27925 9e07cf79b7bce63359d4d746522b00ad 700 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site LH59_27925 9e07cf79b7bce63359d4d746522b00ad 700 SUPERFAMILY SSF54980 409 486 6.47E-25 T 14-10-2018 IPR035647 EF-G domain III/V-like LH59_27925 9e07cf79b7bce63359d4d746522b00ad 700 PRINTS PR00315 GTP-binding elongation factor signature 137 146 4.3E-15 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_27925 9e07cf79b7bce63359d4d746522b00ad 700 PRINTS PR00315 GTP-binding elongation factor signature 58 66 4.3E-15 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_27925 9e07cf79b7bce63359d4d746522b00ad 700 PRINTS PR00315 GTP-binding elongation factor signature 85 95 4.3E-15 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_27925 9e07cf79b7bce63359d4d746522b00ad 700 PRINTS PR00315 GTP-binding elongation factor signature 12 25 4.3E-15 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_27925 9e07cf79b7bce63359d4d746522b00ad 700 PRINTS PR00315 GTP-binding elongation factor signature 101 112 4.3E-15 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_27925 9e07cf79b7bce63359d4d746522b00ad 700 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 186 9.2E-31 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 LH59_27925 9e07cf79b7bce63359d4d746522b00ad 700 Gene3D G3DSA:3.30.70.240 610 681 2.7E-90 T 14-10-2018 LH59_27925 9e07cf79b7bce63359d4d746522b00ad 700 SUPERFAMILY SSF54980 609 696 8.99E-30 T 14-10-2018 IPR035647 EF-G domain III/V-like LH59_27925 9e07cf79b7bce63359d4d746522b00ad 700 Gene3D G3DSA:3.30.230.10 489 694 2.7E-90 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup LH59_14890 9d5924bbcb12634ee6dd4b844629d3cc 528 Gene3D G3DSA:3.10.105.10 276 497 3.4E-56 T 14-10-2018 LH59_14890 9d5924bbcb12634ee6dd4b844629d3cc 528 PIRSF PIRSF002741 1 527 2.6E-117 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 LH59_14890 9d5924bbcb12634ee6dd4b844629d3cc 528 Gene3D G3DSA:3.40.190.10 5 275 2.1E-60 T 14-10-2018 LH59_14890 9d5924bbcb12634ee6dd4b844629d3cc 528 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 76 436 2.5E-79 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain LH59_14890 9d5924bbcb12634ee6dd4b844629d3cc 528 SUPERFAMILY SSF53850 30 521 4.34E-124 T 14-10-2018 LH59_17095 c9bb5dfb5bbbe30577e4cd8c32a37b71 502 SUPERFAMILY SSF46785 21 89 2.73E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_17095 c9bb5dfb5bbbe30577e4cd8c32a37b71 502 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 61 77 8.0E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_17095 c9bb5dfb5bbbe30577e4cd8c32a37b71 502 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 61 8.0E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_17095 c9bb5dfb5bbbe30577e4cd8c32a37b71 502 Pfam PF00392 Bacterial regulatory proteins, gntR family 25 87 1.4E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_17095 c9bb5dfb5bbbe30577e4cd8c32a37b71 502 Gene3D G3DSA:3.40.640.10 133 494 4.8E-118 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_17095 c9bb5dfb5bbbe30577e4cd8c32a37b71 502 SMART SM00345 28 87 1.3E-12 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_17095 c9bb5dfb5bbbe30577e4cd8c32a37b71 502 Gene3D G3DSA:1.10.10.10 22 126 5.4E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_17095 c9bb5dfb5bbbe30577e4cd8c32a37b71 502 SUPERFAMILY SSF53383 130 499 2.11E-86 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_17095 c9bb5dfb5bbbe30577e4cd8c32a37b71 502 Pfam PF00155 Aminotransferase class I and II 158 418 1.8E-22 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LH59_13190 f55da1303f7116317b2f799d69e7549e 343 Gene3D G3DSA:1.10.132.120 105 320 1.6E-82 T 14-10-2018 LH59_13190 f55da1303f7116317b2f799d69e7549e 343 SUPERFAMILY SSF56349 93 315 9.42E-63 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 LH59_13190 f55da1303f7116317b2f799d69e7549e 343 Gene3D G3DSA:3.90.15.10 128 247 1.6E-82 T 14-10-2018 IPR014711 DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type GO:0003677|GO:0003917|GO:0006265 LH59_13190 f55da1303f7116317b2f799d69e7549e 343 Gene3D G3DSA:3.30.66.10 21 103 6.3E-32 T 14-10-2018 IPR035447 DNA topoisomerase I, N-terminal LH59_13190 f55da1303f7116317b2f799d69e7549e 343 SUPERFAMILY SSF55869 37 97 4.71E-21 T 14-10-2018 IPR035447 DNA topoisomerase I, N-terminal LH59_13190 f55da1303f7116317b2f799d69e7549e 343 Pfam PF01028 Eukaryotic DNA topoisomerase I, catalytic core 101 297 5.5E-25 T 14-10-2018 IPR013500 DNA topoisomerase I, catalytic core, eukaryotic-type GO:0003677|GO:0003917|GO:0006265 LH59_21135 4a9e50a8dd3ffb89e6e0943243fc6faf 257 Pfam PF08242 Methyltransferase domain 51 145 1.9E-15 T 14-10-2018 IPR013217 Methyltransferase type 12 LH59_21135 4a9e50a8dd3ffb89e6e0943243fc6faf 257 SUPERFAMILY SSF53335 7 166 1.72E-33 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_21135 4a9e50a8dd3ffb89e6e0943243fc6faf 257 Gene3D G3DSA:3.40.50.150 11 178 3.6E-33 T 14-10-2018 LH59_24510 6f2fdc54ca4140ad2a127812bb100c97 764 Gene3D G3DSA:2.170.130.10 56 189 2.1E-32 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily LH59_24510 6f2fdc54ca4140ad2a127812bb100c97 764 SUPERFAMILY SSF56935 40 764 4.89E-112 T 14-10-2018 LH59_24510 6f2fdc54ca4140ad2a127812bb100c97 764 Gene3D G3DSA:2.40.170.20 190 764 2.7E-146 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_24510 6f2fdc54ca4140ad2a127812bb100c97 764 Pfam PF07715 TonB-dependent Receptor Plug Domain 78 180 8.0E-16 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_24510 6f2fdc54ca4140ad2a127812bb100c97 764 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 747 764 - T 14-10-2018 IPR010917 TonB-dependent receptor, conserved site LH59_24510 6f2fdc54ca4140ad2a127812bb100c97 764 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 80 764 5.9E-90 T 14-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 LH59_24510 6f2fdc54ca4140ad2a127812bb100c97 764 Pfam PF00593 TonB dependent receptor 308 762 6.7E-47 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_22165 1e025663532a492bf2e4574c340c1883 342 Gene3D G3DSA:3.90.180.10 17 335 1.1E-136 T 14-10-2018 LH59_22165 1e025663532a492bf2e4574c340c1883 342 Gene3D G3DSA:3.40.50.720 152 289 1.1E-136 T 14-10-2018 LH59_22165 1e025663532a492bf2e4574c340c1883 342 SUPERFAMILY SSF51735 143 308 3.83E-45 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_22165 1e025663532a492bf2e4574c340c1883 342 SUPERFAMILY SSF50129 3 338 3.35E-56 T 14-10-2018 IPR011032 GroES-like superfamily LH59_22165 1e025663532a492bf2e4574c340c1883 342 SMART SM00829 14 338 1.9E-6 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 LH59_22165 1e025663532a492bf2e4574c340c1883 342 Pfam PF00107 Zinc-binding dehydrogenase 179 304 1.4E-29 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 LH59_22165 1e025663532a492bf2e4574c340c1883 342 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 30 134 8.7E-34 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 LH59_22165 1e025663532a492bf2e4574c340c1883 342 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 64 78 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 LH59_09040 7b5478490ca788950fdf71ed45d24d0c 435 PIRSF PIRSF000521 4 130 3.2E-6 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LH59_09040 7b5478490ca788950fdf71ed45d24d0c 435 PIRSF PIRSF000521 174 417 1.0E-31 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LH59_09040 7b5478490ca788950fdf71ed45d24d0c 435 PIRSF PIRSF000521 121 161 0.073 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LH59_09040 7b5478490ca788950fdf71ed45d24d0c 435 Gene3D G3DSA:3.40.640.10 56 317 1.4E-105 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_09040 7b5478490ca788950fdf71ed45d24d0c 435 Gene3D G3DSA:3.90.1150.10 10 410 1.4E-105 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_09040 7b5478490ca788950fdf71ed45d24d0c 435 TIGRFAM TIGR02407 ectoine_ectB: diaminobutyrate--2-oxoglutarate aminotransferase 4 415 1.2E-195 T 14-10-2018 IPR012773 Ectoine biosynthetic protein GO:0019491|GO:0030170|GO:0047307 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761|MetaCyc: PWY-7855|MetaCyc: PWY-7988 LH59_09040 7b5478490ca788950fdf71ed45d24d0c 435 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 234 270 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LH59_09040 7b5478490ca788950fdf71ed45d24d0c 435 TIGRFAM TIGR00709 dat: 2,4-diaminobutyrate 4-transaminase 2 420 1.6E-143 T 14-10-2018 IPR004637 2,4-diaminobutyrate 4-transaminase GO:0008483|GO:0009058 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761|MetaCyc: PWY-7855|MetaCyc: PWY-7988 LH59_09040 7b5478490ca788950fdf71ed45d24d0c 435 Pfam PF00202 Aminotransferase class-III 20 412 1.7E-77 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LH59_09040 7b5478490ca788950fdf71ed45d24d0c 435 SUPERFAMILY SSF53383 8 414 2.54E-100 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_03065 da8243f14d5d963ff97f350cc35de3ef 298 Gene3D G3DSA:3.40.190.10 176 259 1.8E-5 T 14-10-2018 LH59_03065 da8243f14d5d963ff97f350cc35de3ef 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 9.3E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_03065 da8243f14d5d963ff97f350cc35de3ef 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 9.3E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_03065 da8243f14d5d963ff97f350cc35de3ef 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 9.3E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_03065 da8243f14d5d963ff97f350cc35de3ef 298 SUPERFAMILY SSF53850 89 287 7.45E-33 T 14-10-2018 LH59_03065 da8243f14d5d963ff97f350cc35de3ef 298 Pfam PF03466 LysR substrate binding domain 88 274 9.3E-33 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_03065 da8243f14d5d963ff97f350cc35de3ef 298 Gene3D G3DSA:3.40.190.10 84 175 9.7E-16 T 14-10-2018 LH59_03065 da8243f14d5d963ff97f350cc35de3ef 298 Gene3D G3DSA:1.10.10.10 1 83 3.3E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_03065 da8243f14d5d963ff97f350cc35de3ef 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 4.3E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_03065 da8243f14d5d963ff97f350cc35de3ef 298 SUPERFAMILY SSF46785 1 110 1.01E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_02070 357b70a319738d4e7973b4d6a52f3711 278 Gene3D G3DSA:3.40.50.720 12 270 1.9E-65 T 14-10-2018 LH59_02070 357b70a319738d4e7973b4d6a52f3711 278 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 5.5E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_02070 357b70a319738d4e7973b4d6a52f3711 278 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 5.5E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_02070 357b70a319738d4e7973b4d6a52f3711 278 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 5.5E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_02070 357b70a319738d4e7973b4d6a52f3711 278 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LH59_02070 357b70a319738d4e7973b4d6a52f3711 278 Pfam PF00106 short chain dehydrogenase 13 197 2.2E-44 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_02070 357b70a319738d4e7973b4d6a52f3711 278 PIRSF PIRSF000126 2 268 5.9E-70 T 14-10-2018 LH59_02070 357b70a319738d4e7973b4d6a52f3711 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 2.5E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_02070 357b70a319738d4e7973b4d6a52f3711 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 2.5E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_02070 357b70a319738d4e7973b4d6a52f3711 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 2.5E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_02070 357b70a319738d4e7973b4d6a52f3711 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 2.5E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_02070 357b70a319738d4e7973b4d6a52f3711 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 2.5E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_02070 357b70a319738d4e7973b4d6a52f3711 278 SUPERFAMILY SSF51735 12 230 1.35E-58 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_02065 acdb2ec67ffd289e44dc2c3524f8656c 279 Pfam PF13230 Glutamine amidotransferases class-II 28 198 3.1E-13 T 14-10-2018 IPR026869 Putative glutamine amidotransferase type 2 LH59_02065 acdb2ec67ffd289e44dc2c3524f8656c 279 SUPERFAMILY SSF56235 2 271 3.01E-31 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal LH59_02065 acdb2ec67ffd289e44dc2c3524f8656c 279 Gene3D G3DSA:3.60.20.10 1 277 1.9E-88 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal LH59_07095 471a3e63936a44d24d5a0a4eb0c5fa7b 556 Pfam PF17287 POTRA domain 147 201 2.0E-19 T 14-10-2018 IPR035251 ShlB, POTRA domain LH59_07095 471a3e63936a44d24d5a0a4eb0c5fa7b 556 Pfam PF08479 POTRA domain, ShlB-type 71 146 1.4E-16 T 14-10-2018 IPR013686 Polypeptide-transport-associated, ShlB-type LH59_07095 471a3e63936a44d24d5a0a4eb0c5fa7b 556 Gene3D G3DSA:3.10.20.310 58 146 3.4E-6 T 14-10-2018 LH59_07095 471a3e63936a44d24d5a0a4eb0c5fa7b 556 Pfam PF03865 Haemolysin secretion/activation protein ShlB/FhaC/HecB 207 519 6.5E-100 T 14-10-2018 IPR005565 Haemolysin activator HlyB, C-terminal LH59_07095 471a3e63936a44d24d5a0a4eb0c5fa7b 556 PIRSF PIRSF029745 1 556 3.4E-146 T 14-10-2018 IPR027282 Two partner secretion pathway transporter GO:0015031 LH59_07095 471a3e63936a44d24d5a0a4eb0c5fa7b 556 Gene3D G3DSA:2.40.160.50 179 556 6.2E-99 T 14-10-2018 LH59_01240 610ff5d15427a8526ad5391a7ffbd58c 399 Pfam PF07690 Major Facilitator Superfamily 19 319 2.1E-31 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_01240 610ff5d15427a8526ad5391a7ffbd58c 399 SUPERFAMILY SSF103473 10 387 2.88E-51 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_01240 610ff5d15427a8526ad5391a7ffbd58c 399 Gene3D G3DSA:1.20.1250.20 8 388 9.3E-44 T 14-10-2018 LH59_00870 cdba9273572e06ac220027146aa1b317 203 SUPERFAMILY SSF52833 1 101 9.42E-27 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_00870 cdba9273572e06ac220027146aa1b317 203 Gene3D G3DSA:3.40.30.10 2 195 7.6E-75 T 14-10-2018 LH59_00870 cdba9273572e06ac220027146aa1b317 203 Pfam PF00043 Glutathione S-transferase, C-terminal domain 111 188 8.8E-9 T 14-10-2018 IPR004046 Glutathione S-transferase, C-terminal LH59_00870 cdba9273572e06ac220027146aa1b317 203 Gene3D G3DSA:1.20.1050.10 80 187 7.6E-75 T 14-10-2018 LH59_00870 cdba9273572e06ac220027146aa1b317 203 Pfam PF13417 Glutathione S-transferase, N-terminal domain 4 77 7.2E-17 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 LH59_00870 cdba9273572e06ac220027146aa1b317 203 SUPERFAMILY SSF47616 73 202 1.67E-23 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily LH59_06135 f90b6a9cf5c684285fd8a4305731ddd4 775 Gene3D G3DSA:3.30.70.20 128 205 5.3E-7 T 14-10-2018 LH59_06135 f90b6a9cf5c684285fd8a4305731ddd4 775 SUPERFAMILY SSF53706 214 654 7.37E-85 T 14-10-2018 LH59_06135 f90b6a9cf5c684285fd8a4305731ddd4 775 Pfam PF00384 Molybdopterin oxidoreductase 524 631 5.4E-12 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06135 f90b6a9cf5c684285fd8a4305731ddd4 775 Pfam PF00384 Molybdopterin oxidoreductase 273 412 1.4E-17 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06135 f90b6a9cf5c684285fd8a4305731ddd4 775 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 98 110 - T 14-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06135 f90b6a9cf5c684285fd8a4305731ddd4 775 Gene3D G3DSA:3.10.20.740 1 123 1.8E-41 T 14-10-2018 LH59_06135 f90b6a9cf5c684285fd8a4305731ddd4 775 SMART SM00929 83 123 4.1E-20 T 14-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06135 f90b6a9cf5c684285fd8a4305731ddd4 775 SUPERFAMILY SSF54862 76 211 4.18E-35 T 14-10-2018 LH59_06135 f90b6a9cf5c684285fd8a4305731ddd4 775 SUPERFAMILY SSF54292 1 74 5.52E-21 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 LH59_06135 f90b6a9cf5c684285fd8a4305731ddd4 775 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 146 156 - T 14-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06135 f90b6a9cf5c684285fd8a4305731ddd4 775 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 4 630 6.2E-199 T 14-10-2018 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06135 f90b6a9cf5c684285fd8a4305731ddd4 775 Gene3D G3DSA:3.40.50.740 282 346 2.1E-19 T 14-10-2018 LH59_06135 f90b6a9cf5c684285fd8a4305731ddd4 775 Gene3D G3DSA:3.40.50.740 423 662 1.4E-16 T 14-10-2018 LH59_06135 f90b6a9cf5c684285fd8a4305731ddd4 775 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 1 74 3.7E-20 T 14-10-2018 LH59_06135 f90b6a9cf5c684285fd8a4305731ddd4 775 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 31 48 - T 14-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06135 f90b6a9cf5c684285fd8a4305731ddd4 775 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 83 121 1.9E-16 T 14-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06135 f90b6a9cf5c684285fd8a4305731ddd4 775 Gene3D G3DSA:3.40.228.10 347 410 2.1E-19 T 14-10-2018 LH59_23615 55b1c5c2ea112fde7a744f375786db7d 386 Gene3D G3DSA:1.20.1250.20 4 174 8.8E-13 T 14-10-2018 LH59_23615 55b1c5c2ea112fde7a744f375786db7d 386 Pfam PF07690 Major Facilitator Superfamily 13 326 4.3E-17 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_23615 55b1c5c2ea112fde7a744f375786db7d 386 SUPERFAMILY SSF103473 7 366 4.58E-35 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_23615 55b1c5c2ea112fde7a744f375786db7d 386 Gene3D G3DSA:1.20.1250.20 184 366 3.3E-14 T 14-10-2018 LH59_22445 c103ec583cbd0bdde6c0c4dfe553f7e5 264 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 262 1.2E-18 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_22445 c103ec583cbd0bdde6c0c4dfe553f7e5 264 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 19 263 4.1E-92 T 14-10-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 LH59_22445 c103ec583cbd0bdde6c0c4dfe553f7e5 264 SUPERFAMILY SSF161098 67 254 1.22E-33 T 14-10-2018 IPR035906 MetI-like superfamily LH59_22445 c103ec583cbd0bdde6c0c4dfe553f7e5 264 Gene3D G3DSA:1.10.3720.10 65 263 1.7E-33 T 14-10-2018 IPR035906 MetI-like superfamily LH59_00535 a856f3b9a4f386ee46e7bb3a2a8ed147 256 Pfam PF09339 IclR helix-turn-helix domain 16 61 7.4E-8 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_00535 a856f3b9a4f386ee46e7bb3a2a8ed147 256 SMART SM00346 9 98 1.4E-12 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_00535 a856f3b9a4f386ee46e7bb3a2a8ed147 256 Pfam PF01614 Bacterial transcriptional regulator 130 250 6.0E-9 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal LH59_00535 a856f3b9a4f386ee46e7bb3a2a8ed147 256 Gene3D G3DSA:1.10.10.10 4 75 4.2E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_00535 a856f3b9a4f386ee46e7bb3a2a8ed147 256 SUPERFAMILY SSF55781 66 252 1.05E-34 T 14-10-2018 LH59_00535 a856f3b9a4f386ee46e7bb3a2a8ed147 256 SUPERFAMILY SSF46785 9 80 1.83E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_00535 a856f3b9a4f386ee46e7bb3a2a8ed147 256 Gene3D G3DSA:3.30.450.40 82 253 3.2E-29 T 14-10-2018 IPR029016 GAF-like domain superfamily LH59_23690 6cf3f0fc5b91aedcf95ea37d94787f14 299 SUPERFAMILY SSF53850 88 296 5.61E-14 T 14-10-2018 LH59_23690 6cf3f0fc5b91aedcf95ea37d94787f14 299 Pfam PF03466 LysR substrate binding domain 88 294 8.3E-16 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_23690 6cf3f0fc5b91aedcf95ea37d94787f14 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.7E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_23690 6cf3f0fc5b91aedcf95ea37d94787f14 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.7E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_23690 6cf3f0fc5b91aedcf95ea37d94787f14 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.7E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_23690 6cf3f0fc5b91aedcf95ea37d94787f14 299 Gene3D G3DSA:3.40.190.10 164 268 4.1E-6 T 14-10-2018 LH59_23690 6cf3f0fc5b91aedcf95ea37d94787f14 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 7.5E-16 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_23690 6cf3f0fc5b91aedcf95ea37d94787f14 299 Gene3D G3DSA:3.40.190.10 90 287 4.1E-6 T 14-10-2018 LH59_23690 6cf3f0fc5b91aedcf95ea37d94787f14 299 Gene3D G3DSA:1.10.10.10 1 89 1.5E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_23690 6cf3f0fc5b91aedcf95ea37d94787f14 299 SUPERFAMILY SSF46785 1 81 2.57E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_06415 60fa2979014f0eb1905085f0ef6154ba 383 Gene3D G3DSA:3.40.630.10 10 369 6.0E-108 T 14-10-2018 LH59_06415 60fa2979014f0eb1905085f0ef6154ba 383 TIGRFAM TIGR01892 AcOrn-deacetyl: acetylornithine deacetylase (ArgE) 7 379 5.4E-121 T 14-10-2018 IPR010169 Acetylornithine deacetylase ArgE GO:0005737|GO:0006526|GO:0008777 KEGG: 00220+3.5.1.16|MetaCyc: PWY-5154 LH59_06415 60fa2979014f0eb1905085f0ef6154ba 383 Gene3D G3DSA:3.30.70.360 176 293 6.0E-108 T 14-10-2018 LH59_06415 60fa2979014f0eb1905085f0ef6154ba 383 SUPERFAMILY SSF55031 177 283 6.73E-21 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain LH59_06415 60fa2979014f0eb1905085f0ef6154ba 383 SUPERFAMILY SSF53187 4 379 2.0E-58 T 14-10-2018 LH59_06415 60fa2979014f0eb1905085f0ef6154ba 383 Pfam PF01546 Peptidase family M20/M25/M40 69 378 3.5E-39 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 LH59_06415 60fa2979014f0eb1905085f0ef6154ba 383 Pfam PF07687 Peptidase dimerisation domain 172 282 1.3E-24 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain LH59_06415 60fa2979014f0eb1905085f0ef6154ba 383 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 102 139 - T 14-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 LH59_12035 70ccebe4ea5f28cf4cc977d8aa082ce4 321 SUPERFAMILY SSF52540 12 237 1.66E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_12035 70ccebe4ea5f28cf4cc977d8aa082ce4 321 Gene3D G3DSA:3.40.50.300 6 243 6.4E-70 T 14-10-2018 LH59_12035 70ccebe4ea5f28cf4cc977d8aa082ce4 321 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_12035 70ccebe4ea5f28cf4cc977d8aa082ce4 321 Pfam PF00005 ABC transporter 33 174 1.6E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_12035 70ccebe4ea5f28cf4cc977d8aa082ce4 321 SMART SM00382 41 238 7.7E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_28105 82b89b5a8de86deb9cd48360b2e78530 305 SUPERFAMILY SSF110849 40 133 2.88E-28 T 14-10-2018 IPR036086 ParB/Sulfiredoxin superfamily LH59_28105 82b89b5a8de86deb9cd48360b2e78530 305 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 39 216 8.4E-58 T 14-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 LH59_28105 82b89b5a8de86deb9cd48360b2e78530 305 SMART SM00470 39 131 2.8E-34 T 14-10-2018 IPR003115 ParB/Sulfiredoxin LH59_28105 82b89b5a8de86deb9cd48360b2e78530 305 SUPERFAMILY SSF109709 124 230 2.22E-33 T 14-10-2018 LH59_28105 82b89b5a8de86deb9cd48360b2e78530 305 Gene3D G3DSA:3.90.1530.30 52 117 3.6E-27 T 14-10-2018 LH59_28105 82b89b5a8de86deb9cd48360b2e78530 305 Gene3D G3DSA:1.10.10.2830 118 231 8.3E-36 T 14-10-2018 LH59_28105 82b89b5a8de86deb9cd48360b2e78530 305 Pfam PF02195 ParB-like nuclease domain 41 131 7.1E-25 T 14-10-2018 IPR003115 ParB/Sulfiredoxin LH59_19940 f7da9b40cc8bf53c47760e2b08d112f9 467 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 264 372 8.9E-23 T 14-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LH59_19940 f7da9b40cc8bf53c47760e2b08d112f9 467 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 173 259 2.9E-23 T 14-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LH59_19940 f7da9b40cc8bf53c47760e2b08d112f9 467 Gene3D G3DSA:3.30.310.50 374 467 9.3E-23 T 14-10-2018 LH59_19940 f7da9b40cc8bf53c47760e2b08d112f9 467 Gene3D G3DSA:3.40.120.10 256 373 1.5E-43 T 14-10-2018 LH59_19940 f7da9b40cc8bf53c47760e2b08d112f9 467 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 105 114 - T 14-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LH59_19940 f7da9b40cc8bf53c47760e2b08d112f9 467 SUPERFAMILY SSF53738 12 139 6.67E-36 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LH59_19940 f7da9b40cc8bf53c47760e2b08d112f9 467 SUPERFAMILY SSF53738 161 261 5.89E-28 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LH59_19940 f7da9b40cc8bf53c47760e2b08d112f9 467 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 176 195 8.0E-22 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LH59_19940 f7da9b40cc8bf53c47760e2b08d112f9 467 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 239 254 8.0E-22 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LH59_19940 f7da9b40cc8bf53c47760e2b08d112f9 467 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 210 223 8.0E-22 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LH59_19940 f7da9b40cc8bf53c47760e2b08d112f9 467 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 104 118 8.0E-22 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LH59_19940 f7da9b40cc8bf53c47760e2b08d112f9 467 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 378 455 5.9E-10 T 14-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LH59_19940 f7da9b40cc8bf53c47760e2b08d112f9 467 SUPERFAMILY SSF55957 372 466 2.79E-17 T 14-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LH59_19940 f7da9b40cc8bf53c47760e2b08d112f9 467 Gene3D G3DSA:3.40.120.10 7 156 3.2E-46 T 14-10-2018 LH59_19940 f7da9b40cc8bf53c47760e2b08d112f9 467 SUPERFAMILY SSF53738 263 359 3.02E-32 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LH59_19940 f7da9b40cc8bf53c47760e2b08d112f9 467 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 16 129 1.7E-30 T 14-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LH59_19940 f7da9b40cc8bf53c47760e2b08d112f9 467 Gene3D G3DSA:3.40.120.10 178 255 1.4E-30 T 14-10-2018 LH59_25515 344dffb835d4ca3fb07cede3cbffbf3e 629 SUPERFAMILY SSF55874 7 217 2.49E-68 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_25515 344dffb835d4ca3fb07cede3cbffbf3e 629 PRINTS PR00775 90kDa heat shock protein signature 123 145 3.1E-60 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal LH59_25515 344dffb835d4ca3fb07cede3cbffbf3e 629 PRINTS PR00775 90kDa heat shock protein signature 8 28 3.1E-60 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal LH59_25515 344dffb835d4ca3fb07cede3cbffbf3e 629 PRINTS PR00775 90kDa heat shock protein signature 191 209 3.1E-60 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal LH59_25515 344dffb835d4ca3fb07cede3cbffbf3e 629 PRINTS PR00775 90kDa heat shock protein signature 96 113 3.1E-60 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal LH59_25515 344dffb835d4ca3fb07cede3cbffbf3e 629 PRINTS PR00775 90kDa heat shock protein signature 78 95 3.1E-60 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal LH59_25515 344dffb835d4ca3fb07cede3cbffbf3e 629 PRINTS PR00775 90kDa heat shock protein signature 29 51 3.1E-60 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal LH59_25515 344dffb835d4ca3fb07cede3cbffbf3e 629 PRINTS PR00775 90kDa heat shock protein signature 173 190 3.1E-60 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal LH59_25515 344dffb835d4ca3fb07cede3cbffbf3e 629 Gene3D G3DSA:3.40.50.11260 407 498 1.3E-32 T 14-10-2018 LH59_25515 344dffb835d4ca3fb07cede3cbffbf3e 629 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 30 183 2.3E-11 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_25515 344dffb835d4ca3fb07cede3cbffbf3e 629 Pfam PF00183 Hsp90 protein 218 627 4.4E-129 T 14-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 LH59_25515 344dffb835d4ca3fb07cede3cbffbf3e 629 Hamap MF_00505 Chaperone protein HtpG [htpG]. 5 628 32.724 T 14-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 LH59_25515 344dffb835d4ca3fb07cede3cbffbf3e 629 SUPERFAMILY SSF54211 235 490 2.58E-99 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold LH59_25515 344dffb835d4ca3fb07cede3cbffbf3e 629 Gene3D G3DSA:3.30.565.10 1 231 8.8E-77 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_25515 344dffb835d4ca3fb07cede3cbffbf3e 629 PIRSF PIRSF002583 1 629 7.6E-216 T 14-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 LH59_25515 344dffb835d4ca3fb07cede3cbffbf3e 629 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 28 37 - T 14-10-2018 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0051082 LH59_25515 344dffb835d4ca3fb07cede3cbffbf3e 629 Gene3D G3DSA:3.30.230.80 234 406 9.4E-68 T 14-10-2018 LH59_25515 344dffb835d4ca3fb07cede3cbffbf3e 629 SUPERFAMILY SSF110942 516 628 2.62E-34 T 14-10-2018 IPR037196 HSP90, C-terminal domain LH59_25515 344dffb835d4ca3fb07cede3cbffbf3e 629 SMART SM00387 30 185 1.1E-7 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_25515 344dffb835d4ca3fb07cede3cbffbf3e 629 Gene3D G3DSA:1.20.120.790 499 629 3.7E-42 T 14-10-2018 IPR037196 HSP90, C-terminal domain LH59_07270 fc7dfd751b4a6e2a11b23e1965eb13b3 361 SUPERFAMILY SSF55021 265 359 1.12E-24 T 14-10-2018 LH59_07270 fc7dfd751b4a6e2a11b23e1965eb13b3 361 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 308 315 - T 14-10-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 LH59_07270 fc7dfd751b4a6e2a11b23e1965eb13b3 361 Gene3D G3DSA:1.20.59.10 5 94 2.1E-25 T 14-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 LH59_07270 fc7dfd751b4a6e2a11b23e1965eb13b3 361 Gene3D G3DSA:3.40.190.10 176 259 1.6E-57 T 14-10-2018 LH59_07270 fc7dfd751b4a6e2a11b23e1965eb13b3 361 Pfam PF01817 Chorismate mutase type II 13 91 1.6E-21 T 14-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 LH59_07270 fc7dfd751b4a6e2a11b23e1965eb13b3 361 TIGRFAM TIGR01807 CM_P2: chorismate mutase 9 84 3.8E-25 T 14-10-2018 IPR010957 Gamma/beta/epsilon proteobacterial P-protein, chorismate mutase domain GO:0004106|GO:0005737|GO:0009094 KEGG: 00400+5.4.99.5+4.2.1.51|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7432|MetaCyc: PWY-7626 LH59_07270 fc7dfd751b4a6e2a11b23e1965eb13b3 361 Gene3D G3DSA:3.30.70.260 275 361 3.0E-26 T 14-10-2018 LH59_07270 fc7dfd751b4a6e2a11b23e1965eb13b3 361 PIRSF PIRSF001500 2 361 2.0E-140 T 14-10-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 LH59_07270 fc7dfd751b4a6e2a11b23e1965eb13b3 361 SUPERFAMILY SSF48600 3 92 3.11E-19 T 14-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 LH59_07270 fc7dfd751b4a6e2a11b23e1965eb13b3 361 Pfam PF00800 Prephenate dehydratase 96 270 3.9E-61 T 14-10-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 LH59_07270 fc7dfd751b4a6e2a11b23e1965eb13b3 361 SMART SM00830 13 94 1.5E-27 T 14-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 LH59_07270 fc7dfd751b4a6e2a11b23e1965eb13b3 361 Gene3D G3DSA:3.40.190.10 96 266 1.6E-57 T 14-10-2018 LH59_07270 fc7dfd751b4a6e2a11b23e1965eb13b3 361 SUPERFAMILY SSF53850 94 278 2.61E-58 T 14-10-2018 LH59_01000 d75d633dcbe40710bbbcbac256fb627e 269 Pfam PF04333 MlaA lipoprotein 31 227 6.6E-72 T 14-10-2018 IPR007428 MlaA lipoprotein GO:0016020 LH59_01000 d75d633dcbe40710bbbcbac256fb627e 269 PRINTS PR01805 VacJ lipoprotein signature 100 117 1.3E-26 T 14-10-2018 IPR007428 MlaA lipoprotein GO:0016020 LH59_01000 d75d633dcbe40710bbbcbac256fb627e 269 PRINTS PR01805 VacJ lipoprotein signature 32 45 1.3E-26 T 14-10-2018 IPR007428 MlaA lipoprotein GO:0016020 LH59_01000 d75d633dcbe40710bbbcbac256fb627e 269 PRINTS PR01805 VacJ lipoprotein signature 49 65 1.3E-26 T 14-10-2018 IPR007428 MlaA lipoprotein GO:0016020 LH59_01000 d75d633dcbe40710bbbcbac256fb627e 269 PRINTS PR01805 VacJ lipoprotein signature 136 153 1.3E-26 T 14-10-2018 IPR007428 MlaA lipoprotein GO:0016020 LH59_08055 f7406bde351b66700f58cfc8fc8af174 403 Gene3D G3DSA:3.40.50.2300 54 359 1.0E-108 T 14-10-2018 LH59_08055 f7406bde351b66700f58cfc8fc8af174 403 SUPERFAMILY SSF53822 30 401 5.89E-90 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_08055 f7406bde351b66700f58cfc8fc8af174 403 Gene3D G3DSA:3.40.50.2300 149 367 1.0E-108 T 14-10-2018 LH59_08055 f7406bde351b66700f58cfc8fc8af174 403 Pfam PF13458 Periplasmic binding protein 30 366 2.3E-86 T 14-10-2018 IPR028081 Leucine-binding protein domain LH59_03435 597a122f7b1271e77157b31e57141e23 385 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 56 97 - T 14-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 LH59_03435 597a122f7b1271e77157b31e57141e23 385 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 9 108 1.3E-19 T 14-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain LH59_03435 597a122f7b1271e77157b31e57141e23 385 Pfam PF01872 RibD C-terminal domain 156 358 3.4E-44 T 14-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 LH59_03435 597a122f7b1271e77157b31e57141e23 385 SUPERFAMILY SSF53597 154 363 5.13E-55 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 LH59_03435 597a122f7b1271e77157b31e57141e23 385 PIRSF PIRSF006769 5 369 5.3E-117 T 14-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 LH59_03435 597a122f7b1271e77157b31e57141e23 385 SUPERFAMILY SSF53927 9 153 2.84E-46 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 LH59_03435 597a122f7b1271e77157b31e57141e23 385 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 13 360 9.6E-105 T 14-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 LH59_03435 597a122f7b1271e77157b31e57141e23 385 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 155 365 7.6E-53 T 14-10-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 LH59_03435 597a122f7b1271e77157b31e57141e23 385 Gene3D G3DSA:3.40.430.10 150 370 1.3E-64 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 LH59_03435 597a122f7b1271e77157b31e57141e23 385 Gene3D G3DSA:3.40.140.10 1 149 2.6E-47 T 14-10-2018 LH59_06255 f1917dab8e78528ccacabbb62d15ccd3 699 Gene3D G3DSA:1.10.150.20 537 616 2.8E-29 T 14-10-2018 LH59_06255 f1917dab8e78528ccacabbb62d15ccd3 699 Gene3D G3DSA:2.40.50.140 349 420 8.1E-35 T 14-10-2018 LH59_06255 f1917dab8e78528ccacabbb62d15ccd3 699 SUPERFAMILY SSF52113 622 696 2.8E-18 T 14-10-2018 IPR036420 BRCT domain superfamily LH59_06255 f1917dab8e78528ccacabbb62d15ccd3 699 Gene3D G3DSA:3.30.470.90 74 348 6.4E-93 T 14-10-2018 LH59_06255 f1917dab8e78528ccacabbb62d15ccd3 699 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 16 691 7.1E-249 T 14-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 LH59_06255 f1917dab8e78528ccacabbb62d15ccd3 699 SMART SM00532 8 479 1.8E-263 T 14-10-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 LH59_06255 f1917dab8e78528ccacabbb62d15ccd3 699 Hamap MF_01588 DNA ligase [ligA]. 7 696 54.242 T 14-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 LH59_06255 f1917dab8e78528ccacabbb62d15ccd3 699 PIRSF PIRSF001604 2 699 1.3E-240 T 14-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 LH59_06255 f1917dab8e78528ccacabbb62d15ccd3 699 SUPERFAMILY SSF47781 434 614 7.04E-61 T 14-10-2018 IPR010994 RuvA domain 2-like LH59_06255 f1917dab8e78528ccacabbb62d15ccd3 699 Gene3D G3DSA:3.40.50.10190 621 699 1.2E-25 T 14-10-2018 IPR036420 BRCT domain superfamily LH59_06255 f1917dab8e78528ccacabbb62d15ccd3 699 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 439 465 2.2E-10 T 14-10-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 LH59_06255 f1917dab8e78528ccacabbb62d15ccd3 699 Gene3D G3DSA:1.10.150.20 463 536 3.3E-26 T 14-10-2018 LH59_06255 f1917dab8e78528ccacabbb62d15ccd3 699 SUPERFAMILY SSF56091 9 347 5.25E-114 T 14-10-2018 LH59_06255 f1917dab8e78528ccacabbb62d15ccd3 699 SUPERFAMILY SSF50249 348 431 8.39E-30 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_06255 f1917dab8e78528ccacabbb62d15ccd3 699 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 362 377 - T 14-10-2018 IPR033136 NAD-dependent DNA ligase, conserved site LH59_06255 f1917dab8e78528ccacabbb62d15ccd3 699 SMART SM00292 622 699 2.5E-11 T 14-10-2018 IPR001357 BRCT domain LH59_06255 f1917dab8e78528ccacabbb62d15ccd3 699 Gene3D G3DSA:1.10.287.610 8 73 9.6E-30 T 14-10-2018 LH59_06255 f1917dab8e78528ccacabbb62d15ccd3 699 Gene3D G3DSA:2.20.70.80 422 462 4.1E-20 T 14-10-2018 LH59_06255 f1917dab8e78528ccacabbb62d15ccd3 699 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 352 429 7.5E-37 T 14-10-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 LH59_06255 f1917dab8e78528ccacabbb62d15ccd3 699 Pfam PF14520 Helix-hairpin-helix domain 477 532 1.2E-6 T 14-10-2018 LH59_06255 f1917dab8e78528ccacabbb62d15ccd3 699 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 11 349 1.2E-117 T 14-10-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 LH59_06255 f1917dab8e78528ccacabbb62d15ccd3 699 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 126 155 - T 14-10-2018 IPR018239 NAD-dependent DNA ligase, active site LH59_06255 f1917dab8e78528ccacabbb62d15ccd3 699 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 624 696 1.6E-14 T 14-10-2018 IPR001357 BRCT domain LH59_06255 f1917dab8e78528ccacabbb62d15ccd3 699 Pfam PF12826 Helix-hairpin-helix motif 541 604 7.1E-25 T 14-10-2018 LH59_06255 f1917dab8e78528ccacabbb62d15ccd3 699 SMART SM00278 511 530 21.0 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 LH59_06255 f1917dab8e78528ccacabbb62d15ccd3 699 SMART SM00278 477 496 6.0 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 LH59_06255 f1917dab8e78528ccacabbb62d15ccd3 699 SMART SM00278 543 562 300.0 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 LH59_06255 f1917dab8e78528ccacabbb62d15ccd3 699 SMART SM00278 575 594 83.0 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 LH59_24565 2fac57028d4b245f0fa1a796daa5a84e 628 SUPERFAMILY SSF48452 227 402 9.91E-12 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_24565 2fac57028d4b245f0fa1a796daa5a84e 628 Gene3D G3DSA:1.25.40.10 448 621 1.6E-31 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_24565 2fac57028d4b245f0fa1a796daa5a84e 628 Gene3D G3DSA:1.25.40.10 110 267 5.1E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_24565 2fac57028d4b245f0fa1a796daa5a84e 628 SUPERFAMILY SSF48452 449 616 1.14E-24 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_24565 2fac57028d4b245f0fa1a796daa5a84e 628 Pfam PF14559 Tetratricopeptide repeat 561 619 1.3E-6 T 14-10-2018 LH59_24565 2fac57028d4b245f0fa1a796daa5a84e 628 Pfam PF13432 Tetratricopeptide repeat 332 401 7.9E-4 T 14-10-2018 LH59_24565 2fac57028d4b245f0fa1a796daa5a84e 628 Pfam PF13432 Tetratricopeptide repeat 204 260 0.0017 T 14-10-2018 LH59_24565 2fac57028d4b245f0fa1a796daa5a84e 628 Pfam PF13432 Tetratricopeptide repeat 500 548 1.3E-6 T 14-10-2018 LH59_24565 2fac57028d4b245f0fa1a796daa5a84e 628 SMART SM00028 328 361 170.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 LH59_24565 2fac57028d4b245f0fa1a796daa5a84e 628 SMART SM00028 479 512 18.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 LH59_24565 2fac57028d4b245f0fa1a796daa5a84e 628 SMART SM00028 581 614 0.18 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 LH59_24565 2fac57028d4b245f0fa1a796daa5a84e 628 SMART SM00028 410 443 150.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 LH59_24565 2fac57028d4b245f0fa1a796daa5a84e 628 SMART SM00028 227 260 26.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 LH59_24565 2fac57028d4b245f0fa1a796daa5a84e 628 SMART SM00028 513 547 15.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 LH59_24565 2fac57028d4b245f0fa1a796daa5a84e 628 Gene3D G3DSA:1.25.40.10 268 444 1.0E-12 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_13100 bcfa47ec7e9def9f90bcf5c8d026ef95 408 SUPERFAMILY SSF141868 169 407 2.09E-62 T 14-10-2018 IPR035919 EAL domain superfamily LH59_13100 bcfa47ec7e9def9f90bcf5c8d026ef95 408 SMART SM00052 154 400 8.3E-57 T 14-10-2018 IPR001633 EAL domain LH59_13100 bcfa47ec7e9def9f90bcf5c8d026ef95 408 SMART SM00448 10 133 1.4E-10 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_13100 bcfa47ec7e9def9f90bcf5c8d026ef95 408 Gene3D G3DSA:3.40.50.2300 2 144 8.9E-19 T 14-10-2018 LH59_13100 bcfa47ec7e9def9f90bcf5c8d026ef95 408 Pfam PF00072 Response regulator receiver domain 12 133 1.1E-13 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_13100 bcfa47ec7e9def9f90bcf5c8d026ef95 408 Gene3D G3DSA:3.20.20.450 158 408 2.8E-66 T 14-10-2018 IPR035919 EAL domain superfamily LH59_13100 bcfa47ec7e9def9f90bcf5c8d026ef95 408 Pfam PF00563 EAL domain 161 395 6.5E-54 T 14-10-2018 IPR001633 EAL domain LH59_13100 bcfa47ec7e9def9f90bcf5c8d026ef95 408 SUPERFAMILY SSF52172 9 139 1.85E-20 T 14-10-2018 IPR011006 CheY-like superfamily LH59_07955 8c71255548112c25ac16f4e1d2cf3e93 504 Gene3D G3DSA:3.30.565.10 342 500 1.1E-31 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_07955 8c71255548112c25ac16f4e1d2cf3e93 504 PRINTS PR00344 Bacterial sensor protein C-terminal signature 451 469 5.8E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_07955 8c71255548112c25ac16f4e1d2cf3e93 504 PRINTS PR00344 Bacterial sensor protein C-terminal signature 419 433 5.8E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_07955 8c71255548112c25ac16f4e1d2cf3e93 504 PRINTS PR00344 Bacterial sensor protein C-terminal signature 437 447 5.8E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_07955 8c71255548112c25ac16f4e1d2cf3e93 504 SUPERFAMILY SSF55874 326 496 1.31E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_07955 8c71255548112c25ac16f4e1d2cf3e93 504 SMART SM00388 272 337 6.1E-18 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_07955 8c71255548112c25ac16f4e1d2cf3e93 504 SMART SM00387 382 496 1.5E-34 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_07955 8c71255548112c25ac16f4e1d2cf3e93 504 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 385 494 2.1E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_07955 8c71255548112c25ac16f4e1d2cf3e93 504 Pfam PF00512 His Kinase A (phospho-acceptor) domain 272 336 4.2E-15 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_07955 8c71255548112c25ac16f4e1d2cf3e93 504 Gene3D G3DSA:1.10.287.130 223 338 1.7E-20 T 14-10-2018 LH59_07955 8c71255548112c25ac16f4e1d2cf3e93 504 Pfam PF08521 Two-component sensor kinase N-terminal 51 195 4.5E-35 T 14-10-2018 IPR013727 Two-component sensor kinase, N-terminal LH59_07955 8c71255548112c25ac16f4e1d2cf3e93 504 SUPERFAMILY SSF47384 255 336 3.53E-17 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 LH59_10435 1da9feb671930b52f134ce5a314da619 208 SUPERFAMILY SSF52540 2 190 5.97E-39 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_10435 1da9feb671930b52f134ce5a314da619 208 SMART SM00382 26 207 0.0045 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_10435 1da9feb671930b52f134ce5a314da619 208 TIGRFAM TIGR01189 ccmA: heme ABC exporter, ATP-binding protein CcmA 2 203 2.7E-62 T 14-10-2018 IPR005895 ABC transporter, haem export, CcmA GO:0005215|GO:0017004 LH59_10435 1da9feb671930b52f134ce5a314da619 208 Pfam PF00005 ABC transporter 18 160 6.1E-21 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_10435 1da9feb671930b52f134ce5a314da619 208 Gene3D G3DSA:3.40.50.300 1 200 7.4E-44 T 14-10-2018 LH59_05550 6bd5184b0206e6d2682bd4117988c204 399 SUPERFAMILY SSF51556 52 358 3.26E-67 T 14-10-2018 IPR032466 Metal-dependent hydrolase LH59_05550 6bd5184b0206e6d2682bd4117988c204 399 Gene3D G3DSA:2.30.40.10 3 388 1.5E-107 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 LH59_05550 6bd5184b0206e6d2682bd4117988c204 399 SUPERFAMILY SSF51338 1 66 1.8E-10 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 LH59_05550 6bd5184b0206e6d2682bd4117988c204 399 Gene3D G3DSA:3.20.20.140 53 348 1.5E-107 T 14-10-2018 LH59_05550 6bd5184b0206e6d2682bd4117988c204 399 Pfam PF07969 Amidohydrolase family 155 388 1.9E-18 T 14-10-2018 IPR013108 Amidohydrolase 3 LH59_05550 6bd5184b0206e6d2682bd4117988c204 399 SUPERFAMILY SSF51338 343 389 5.13E-6 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 LH59_20715 af35001b2d886fbcfe09fae9faa32c74 829 Gene3D G3DSA:2.60.40.2070 752 829 3.4E-16 T 14-10-2018 LH59_20715 af35001b2d886fbcfe09fae9faa32c74 829 Pfam PF13953 PapC C-terminal domain 755 813 5.1E-11 T 14-10-2018 IPR025949 PapC-like, C-terminal domain LH59_20715 af35001b2d886fbcfe09fae9faa32c74 829 Pfam PF00577 Outer membrane usher protein 185 742 2.2E-162 T 14-10-2018 IPR000015 Outer membrane usher protein GO:0009297|GO:0015473|GO:0016020 LH59_20715 af35001b2d886fbcfe09fae9faa32c74 829 Gene3D G3DSA:2.60.40.3110 257 345 3.9E-28 T 14-10-2018 LH59_20715 af35001b2d886fbcfe09fae9faa32c74 829 SUPERFAMILY SSF141729 22 144 2.35E-21 T 14-10-2018 IPR037224 PapC, N-terminal domain superfamily GO:0005515 LH59_20715 af35001b2d886fbcfe09fae9faa32c74 829 Pfam PF13954 PapC N-terminal domain 23 167 2.4E-32 T 14-10-2018 IPR025885 PapC, N-terminal domain GO:0005515 LH59_20715 af35001b2d886fbcfe09fae9faa32c74 829 Gene3D G3DSA:2.60.40.2610 657 748 4.7E-13 T 14-10-2018 LH59_20715 af35001b2d886fbcfe09fae9faa32c74 829 Gene3D G3DSA:3.10.20.410 21 145 2.8E-18 T 14-10-2018 LH59_24325 24812d5f8169e1c9cefade5cd7bd8ec6 321 Pfam PF03466 LysR substrate binding domain 101 312 6.2E-34 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_24325 24812d5f8169e1c9cefade5cd7bd8ec6 321 Gene3D G3DSA:1.10.10.10 14 102 9.7E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_24325 24812d5f8169e1c9cefade5cd7bd8ec6 321 Gene3D G3DSA:3.40.190.10 184 286 1.8E-51 T 14-10-2018 LH59_24325 24812d5f8169e1c9cefade5cd7bd8ec6 321 SUPERFAMILY SSF46785 14 125 1.32E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_24325 24812d5f8169e1c9cefade5cd7bd8ec6 321 Gene3D G3DSA:3.40.190.10 106 303 1.8E-51 T 14-10-2018 LH59_24325 24812d5f8169e1c9cefade5cd7bd8ec6 321 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 17 74 5.4E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_24325 24812d5f8169e1c9cefade5cd7bd8ec6 321 SUPERFAMILY SSF53850 102 318 7.39E-40 T 14-10-2018 LH59_24325 24812d5f8169e1c9cefade5cd7bd8ec6 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 53 8.6E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_24325 24812d5f8169e1c9cefade5cd7bd8ec6 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 53 64 8.6E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_24325 24812d5f8169e1c9cefade5cd7bd8ec6 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 43 8.6E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_21395 a313ff4d9a468866534e218f08e7da0c 515 SMART SM00382 291 486 2.0E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_21395 a313ff4d9a468866534e218f08e7da0c 515 SMART SM00382 32 232 1.1E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_21395 a313ff4d9a468866534e218f08e7da0c 515 SUPERFAMILY SSF52540 6 234 2.47E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_21395 a313ff4d9a468866534e218f08e7da0c 515 Pfam PF00005 ABC transporter 284 437 3.0E-16 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_21395 a313ff4d9a468866534e218f08e7da0c 515 Gene3D G3DSA:3.40.50.300 1 239 2.0E-53 T 14-10-2018 LH59_21395 a313ff4d9a468866534e218f08e7da0c 515 TIGRFAM TIGR02633 xylG: D-xylose ABC transporter, ATP-binding protein 7 506 2.4E-233 T 14-10-2018 IPR013455 ABC transporter, D-xylose, ATP-binding protein GO:0005524|GO:0015614|GO:0015753|GO:0016020 LH59_21395 a313ff4d9a468866534e218f08e7da0c 515 Pfam PF00005 ABC transporter 23 176 1.3E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_21395 a313ff4d9a468866534e218f08e7da0c 515 ProSitePatterns PS00211 ABC transporters family signature. 410 424 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_21395 a313ff4d9a468866534e218f08e7da0c 515 Gene3D G3DSA:3.40.50.300 249 510 2.5E-42 T 14-10-2018 LH59_21395 a313ff4d9a468866534e218f08e7da0c 515 SUPERFAMILY SSF52540 263 498 5.42E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_02015 0c3aa1c8f048b73a5b7864ffc2876a8d 513 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 512 50.784 T 14-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 LH59_02015 0c3aa1c8f048b73a5b7864ffc2876a8d 513 SUPERFAMILY SSF50615 10 94 3.14E-28 T 14-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 LH59_02015 0c3aa1c8f048b73a5b7864ffc2876a8d 513 SUPERFAMILY SSF52540 96 381 3.75E-95 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_02015 0c3aa1c8f048b73a5b7864ffc2876a8d 513 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 382 507 1.8E-45 T 14-10-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 LH59_02015 0c3aa1c8f048b73a5b7864ffc2876a8d 513 SUPERFAMILY SSF47917 383 510 2.62E-45 T 14-10-2018 LH59_02015 0c3aa1c8f048b73a5b7864ffc2876a8d 513 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 366 375 - T 14-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 LH59_02015 0c3aa1c8f048b73a5b7864ffc2876a8d 513 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 510 4.7E-249 T 14-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 LH59_02015 0c3aa1c8f048b73a5b7864ffc2876a8d 513 Gene3D G3DSA:1.20.150.20 383 512 4.1E-46 T 14-10-2018 IPR038376 ATP synthase, alpha subunit, C-terminal domain superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 LH59_02015 0c3aa1c8f048b73a5b7864ffc2876a8d 513 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 25 92 2.3E-16 T 14-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 LH59_02015 0c3aa1c8f048b73a5b7864ffc2876a8d 513 Gene3D G3DSA:2.40.30.20 1 93 5.4E-34 T 14-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 LH59_02015 0c3aa1c8f048b73a5b7864ffc2876a8d 513 Gene3D G3DSA:3.40.50.300 94 382 2.4E-131 T 14-10-2018 LH59_02015 0c3aa1c8f048b73a5b7864ffc2876a8d 513 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 375 1.8E-74 T 14-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 LH59_02015 0c3aa1c8f048b73a5b7864ffc2876a8d 513 PIRSF PIRSF039088 1 513 3.2E-238 T 14-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 LH59_04275 feaffe8f185ddc2cc310c85674d58cf3 642 Gene3D G3DSA:3.40.720.10 266 545 5.4E-128 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 LH59_04275 feaffe8f185ddc2cc310c85674d58cf3 642 Gene3D G3DSA:3.30.1120.80 547 622 5.4E-128 T 14-10-2018 LH59_04275 feaffe8f185ddc2cc310c85674d58cf3 642 Pfam PF00884 Sulfatase 272 538 7.7E-40 T 14-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 LH59_04275 feaffe8f185ddc2cc310c85674d58cf3 642 PIRSF PIRSF005091 13 598 5.7E-82 T 14-10-2018 IPR012160 Lipoteichoic acid synthase-like LH59_04275 feaffe8f185ddc2cc310c85674d58cf3 642 SUPERFAMILY SSF53649 270 592 3.49E-63 T 14-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 LH59_27075 386d8f00875e5bebe3d9c84094d8e8b1 297 SUPERFAMILY SSF53474 6 293 4.52E-63 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_27075 386d8f00875e5bebe3d9c84094d8e8b1 297 Pfam PF00561 alpha/beta hydrolase fold 28 146 6.1E-18 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_27075 386d8f00875e5bebe3d9c84094d8e8b1 297 Gene3D G3DSA:3.40.50.1820 9 292 7.1E-73 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_13215 52ad39d85b7428c95f293ec0147276d4 315 Gene3D G3DSA:3.40.50.720 24 305 6.3E-101 T 14-10-2018 LH59_13215 52ad39d85b7428c95f293ec0147276d4 315 Gene3D G3DSA:3.40.50.720 101 282 6.3E-101 T 14-10-2018 LH59_13215 52ad39d85b7428c95f293ec0147276d4 315 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 33 310 2.0E-20 T 14-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 LH59_13215 52ad39d85b7428c95f293ec0147276d4 315 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 144 172 - T 14-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 LH59_13215 52ad39d85b7428c95f293ec0147276d4 315 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 109 279 3.3E-50 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 LH59_13215 52ad39d85b7428c95f293ec0147276d4 315 SUPERFAMILY SSF52283 6 133 7.75E-31 T 14-10-2018 LH59_13215 52ad39d85b7428c95f293ec0147276d4 315 SUPERFAMILY SSF51735 100 280 1.21E-53 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_15735 953f69f62499b38aa44aa63331df382d 770 SUPERFAMILY SSF56003 62 244 1.74E-30 T 14-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 LH59_15735 953f69f62499b38aa44aa63331df382d 770 Gene3D G3DSA:3.30.365.10 606 760 1.0E-35 T 14-10-2018 LH59_15735 953f69f62499b38aa44aa63331df382d 770 PIRSF PIRSF036389 11 755 3.5E-183 T 14-10-2018 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related LH59_15735 953f69f62499b38aa44aa63331df382d 770 Gene3D G3DSA:3.30.365.10 354 445 1.6E-46 T 14-10-2018 LH59_15735 953f69f62499b38aa44aa63331df382d 770 Gene3D G3DSA:3.30.365.10 330 562 1.6E-46 T 14-10-2018 LH59_15735 953f69f62499b38aa44aa63331df382d 770 Gene3D G3DSA:3.90.1170.50 202 303 1.8E-7 T 14-10-2018 LH59_15735 953f69f62499b38aa44aa63331df382d 770 SUPERFAMILY SSF54665 219 305 2.35E-7 T 14-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily LH59_15735 953f69f62499b38aa44aa63331df382d 770 SMART SM01008 218 304 5.5E-16 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead LH59_15735 953f69f62499b38aa44aa63331df382d 770 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 615 701 4.8E-11 T 14-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 LH59_15735 953f69f62499b38aa44aa63331df382d 770 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 327 585 4.8E-29 T 14-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 LH59_15735 953f69f62499b38aa44aa63331df382d 770 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 67 214 5.1E-21 T 14-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 LH59_15735 953f69f62499b38aa44aa63331df382d 770 Gene3D G3DSA:3.30.365.10 53 191 2.6E-30 T 14-10-2018 LH59_15735 953f69f62499b38aa44aa63331df382d 770 SUPERFAMILY SSF56003 324 758 5.5E-111 T 14-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 LH59_23560 d33ea80a9abd611e8192f09f0e2865b4 798 SMART SM00965 65 115 4.0E-6 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 LH59_23560 d33ea80a9abd611e8192f09f0e2865b4 798 SUPERFAMILY SSF56935 121 798 4.07E-114 T 14-10-2018 LH59_23560 d33ea80a9abd611e8192f09f0e2865b4 798 Gene3D G3DSA:2.170.130.10 133 264 3.2E-38 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily LH59_23560 d33ea80a9abd611e8192f09f0e2865b4 798 Gene3D G3DSA:3.55.50.30 41 113 1.7E-20 T 14-10-2018 LH59_23560 d33ea80a9abd611e8192f09f0e2865b4 798 Pfam PF07715 TonB-dependent Receptor Plug Domain 156 255 2.6E-11 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_23560 d33ea80a9abd611e8192f09f0e2865b4 798 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 781 798 - T 14-10-2018 IPR010917 TonB-dependent receptor, conserved site LH59_23560 d33ea80a9abd611e8192f09f0e2865b4 798 Gene3D G3DSA:2.40.170.20 267 798 3.4E-167 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_23560 d33ea80a9abd611e8192f09f0e2865b4 798 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 158 798 3.4E-104 T 14-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 LH59_23560 d33ea80a9abd611e8192f09f0e2865b4 798 Pfam PF00593 TonB dependent receptor 351 796 4.0E-45 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_19350 4ed6b5f04a259a9a969ce6ec38e07658 360 Gene3D G3DSA:3.40.50.360 71 349 1.7E-19 T 14-10-2018 IPR029039 Flavoprotein-like superfamily LH59_19350 4ed6b5f04a259a9a969ce6ec38e07658 360 SUPERFAMILY SSF52218 98 344 7.16E-27 T 14-10-2018 IPR029039 Flavoprotein-like superfamily LH59_19350 4ed6b5f04a259a9a969ce6ec38e07658 360 Pfam PF03358 NADPH-dependent FMN reductase 102 304 3.7E-30 T 14-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 LH59_16575 48ac2a778f63ccb16d3d7a449248fc1c 317 Pfam PF00561 alpha/beta hydrolase fold 68 263 2.5E-7 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_16575 48ac2a778f63ccb16d3d7a449248fc1c 317 SUPERFAMILY SSF53474 53 315 2.53E-31 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_16575 48ac2a778f63ccb16d3d7a449248fc1c 317 Gene3D G3DSA:3.40.50.1820 1 316 2.7E-90 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_03080 9ffac2da9d44f03c4c2fa1e96cb45d8f 275 Gene3D G3DSA:3.40.190.10 24 259 1.7E-59 T 14-10-2018 LH59_03080 9ffac2da9d44f03c4c2fa1e96cb45d8f 275 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 59 72 - T 14-10-2018 IPR018313 Solute-binding protein family 3, conserved site LH59_03080 9ffac2da9d44f03c4c2fa1e96cb45d8f 275 Gene3D G3DSA:3.40.190.10 123 216 1.7E-59 T 14-10-2018 LH59_03080 9ffac2da9d44f03c4c2fa1e96cb45d8f 275 SMART SM00062 35 259 4.2E-50 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_03080 9ffac2da9d44f03c4c2fa1e96cb45d8f 275 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 38 257 2.5E-52 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_03080 9ffac2da9d44f03c4c2fa1e96cb45d8f 275 SUPERFAMILY SSF53850 1 258 6.23E-57 T 14-10-2018 LH59_03130 2315c46353a61e569ac7ec48205c94c8 592 SUPERFAMILY SSF161098 5 282 6.41E-47 T 14-10-2018 IPR035906 MetI-like superfamily LH59_03130 2315c46353a61e569ac7ec48205c94c8 592 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 382 587 1.0E-11 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_03130 2315c46353a61e569ac7ec48205c94c8 592 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 276 6.9E-12 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_03130 2315c46353a61e569ac7ec48205c94c8 592 Gene3D G3DSA:1.10.3720.10 304 590 2.5E-30 T 14-10-2018 IPR035906 MetI-like superfamily LH59_03130 2315c46353a61e569ac7ec48205c94c8 592 Gene3D G3DSA:1.10.3720.10 14 283 9.2E-46 T 14-10-2018 IPR035906 MetI-like superfamily LH59_03130 2315c46353a61e569ac7ec48205c94c8 592 SUPERFAMILY SSF161098 300 589 1.05E-38 T 14-10-2018 IPR035906 MetI-like superfamily LH59_17900 df0e3e94b55d12014c0c9be2fb3a54d5 81 SMART SM00357 17 81 2.3E-32 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 LH59_17900 df0e3e94b55d12014c0c9be2fb3a54d5 81 PIRSF PIRSF002599 12 81 6.4E-24 T 14-10-2018 IPR012156 Cold shock, CspA GO:0003676 LH59_17900 df0e3e94b55d12014c0c9be2fb3a54d5 81 Gene3D G3DSA:2.40.50.140 15 81 2.0E-31 T 14-10-2018 LH59_17900 df0e3e94b55d12014c0c9be2fb3a54d5 81 PRINTS PR00050 Cold shock protein signature 39 48 3.1E-17 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 LH59_17900 df0e3e94b55d12014c0c9be2fb3a54d5 81 PRINTS PR00050 Cold shock protein signature 54 72 3.1E-17 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 LH59_17900 df0e3e94b55d12014c0c9be2fb3a54d5 81 PRINTS PR00050 Cold shock protein signature 18 33 3.1E-17 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 LH59_17900 df0e3e94b55d12014c0c9be2fb3a54d5 81 Pfam PF00313 'Cold-shock' DNA-binding domain 17 80 3.1E-31 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 LH59_17900 df0e3e94b55d12014c0c9be2fb3a54d5 81 SUPERFAMILY SSF50249 15 79 2.36E-26 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_17900 df0e3e94b55d12014c0c9be2fb3a54d5 81 ProSitePatterns PS00352 'Cold-shock' domain signature. 29 48 - T 14-10-2018 IPR019844 Cold-shock conserved site LH59_14175 307dd9841f855aea23abbf52345f15f6 527 ProSitePatterns PS00455 Putative AMP-binding domain signature. 173 184 - T 14-10-2018 IPR020845 AMP-binding, conserved site LH59_14175 307dd9841f855aea23abbf52345f15f6 527 SUPERFAMILY SSF56801 4 510 3.79E-121 T 14-10-2018 LH59_14175 307dd9841f855aea23abbf52345f15f6 527 Gene3D G3DSA:3.40.50.12780 1 409 8.4E-88 T 14-10-2018 LH59_14175 307dd9841f855aea23abbf52345f15f6 527 Gene3D G3DSA:3.30.300.30 410 511 1.4E-25 T 14-10-2018 LH59_14175 307dd9841f855aea23abbf52345f15f6 527 Pfam PF13193 AMP-binding enzyme C-terminal domain 425 500 1.4E-14 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain LH59_14175 307dd9841f855aea23abbf52345f15f6 527 Pfam PF00501 AMP-binding enzyme 11 416 4.8E-73 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 LH59_11735 4c63297220fbdde39452040be3f13c24 788 SUPERFAMILY SSF52009 345 465 6.67E-35 T 14-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 LH59_11735 4c63297220fbdde39452040be3f13c24 788 Gene3D G3DSA:3.50.30.10 355 465 1.4E-40 T 14-10-2018 LH59_11735 4c63297220fbdde39452040be3f13c24 788 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 412 423 - T 14-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 LH59_11735 4c63297220fbdde39452040be3f13c24 788 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 692 710 - T 14-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 LH59_11735 4c63297220fbdde39452040be3f13c24 788 PIRSF PIRSF000854 1 788 0.0 T 14-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 LH59_11735 4c63297220fbdde39452040be3f13c24 788 Gene3D G3DSA:3.30.470.20 191 354 5.4E-57 T 14-10-2018 LH59_11735 4c63297220fbdde39452040be3f13c24 788 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 16 347 5.0E-115 T 14-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 LH59_11735 4c63297220fbdde39452040be3f13c24 788 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 478 787 9.7E-56 T 14-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 LH59_11735 4c63297220fbdde39452040be3f13c24 788 Gene3D G3DSA:3.30.1490.20 1 190 2.3E-70 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 LH59_11735 4c63297220fbdde39452040be3f13c24 788 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 4 787 0.0 T 14-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 LH59_11735 4c63297220fbdde39452040be3f13c24 788 SUPERFAMILY SSF51621 464 787 2.02E-91 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 LH59_11735 4c63297220fbdde39452040be3f13c24 788 Pfam PF00391 PEP-utilising enzyme, mobile domain 382 453 1.8E-26 T 14-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 LH59_11735 4c63297220fbdde39452040be3f13c24 788 SUPERFAMILY SSF56059 1 383 7.06E-107 T 14-10-2018 LH59_11735 4c63297220fbdde39452040be3f13c24 788 Gene3D G3DSA:3.20.20.60 476 788 1.9E-96 T 14-10-2018 LH59_10280 c8681704ce9d128875a89ed81f232b53 542 Pfam PF01593 Flavin containing amine oxidoreductase 21 346 6.2E-17 T 14-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 LH59_10280 c8681704ce9d128875a89ed81f232b53 542 Gene3D G3DSA:3.50.50.60 191 327 2.4E-16 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_10280 c8681704ce9d128875a89ed81f232b53 542 SUPERFAMILY SSF51905 7 533 6.62E-44 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_10280 c8681704ce9d128875a89ed81f232b53 542 Gene3D G3DSA:3.50.50.60 9 115 1.9E-14 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_20930 12882fb16496e162bd6bf9bd79ca3289 338 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_20930 12882fb16496e162bd6bf9bd79ca3289 338 Pfam PF00005 ABC transporter 37 187 3.6E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_20930 12882fb16496e162bd6bf9bd79ca3289 338 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 239 303 9.4E-21 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_20930 12882fb16496e162bd6bf9bd79ca3289 338 SUPERFAMILY SSF52540 45 308 1.63E-66 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_20930 12882fb16496e162bd6bf9bd79ca3289 338 Gene3D G3DSA:3.40.50.300 25 332 2.3E-94 T 14-10-2018 LH59_20930 12882fb16496e162bd6bf9bd79ca3289 338 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 237 323 1.3E-29 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_20930 12882fb16496e162bd6bf9bd79ca3289 338 SMART SM00382 45 237 7.5E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_27975 7e4692e516fabffca8167ea91c0d3afd 1370 Gene3D G3DSA:3.90.1800.10 1280 1362 6.8E-11 T 14-10-2018 LH59_27975 7e4692e516fabffca8167ea91c0d3afd 1370 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 8 1366 0.0 T 14-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LH59_27975 7e4692e516fabffca8167ea91c0d3afd 1370 Gene3D G3DSA:3.90.1100.10 18 174 5.1E-51 T 14-10-2018 LH59_27975 7e4692e516fabffca8167ea91c0d3afd 1370 Gene3D G3DSA:3.90.1100.10 648 719 1.9E-21 T 14-10-2018 LH59_27975 7e4692e516fabffca8167ea91c0d3afd 1370 Gene3D G3DSA:3.90.1110.10 321 447 2.5E-32 T 14-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LH59_27975 7e4692e516fabffca8167ea91c0d3afd 1370 Pfam PF04561 RNA polymerase Rpb2, domain 2 354 460 2.2E-16 T 14-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LH59_27975 7e4692e516fabffca8167ea91c0d3afd 1370 Pfam PF04561 RNA polymerase Rpb2, domain 2 155 227 3.0E-5 T 14-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LH59_27975 7e4692e516fabffca8167ea91c0d3afd 1370 Pfam PF00562 RNA polymerase Rpb2, domain 6 725 1292 4.3E-158 T 14-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LH59_27975 7e4692e516fabffca8167ea91c0d3afd 1370 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 13 1370 12.212 T 14-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LH59_27975 7e4692e516fabffca8167ea91c0d3afd 1370 Gene3D G3DSA:3.90.1100.10 448 636 2.3E-71 T 14-10-2018 LH59_27975 7e4692e516fabffca8167ea91c0d3afd 1370 SUPERFAMILY SSF64484 12 1368 0.0 T 14-10-2018 LH59_27975 7e4692e516fabffca8167ea91c0d3afd 1370 Gene3D G3DSA:2.40.50.150 839 956 9.4E-42 T 14-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LH59_27975 7e4692e516fabffca8167ea91c0d3afd 1370 Gene3D G3DSA:2.40.50.100 720 794 1.7E-28 T 14-10-2018 LH59_27975 7e4692e516fabffca8167ea91c0d3afd 1370 Pfam PF04565 RNA polymerase Rpb2, domain 3 519 586 1.2E-31 T 14-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LH59_27975 7e4692e516fabffca8167ea91c0d3afd 1370 Pfam PF04560 RNA polymerase Rpb2, domain 7 1294 1368 7.5E-26 T 14-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LH59_27975 7e4692e516fabffca8167ea91c0d3afd 1370 Pfam PF04563 RNA polymerase beta subunit 27 506 7.8E-36 T 14-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LH59_27975 7e4692e516fabffca8167ea91c0d3afd 1370 ProSitePatterns PS01166 RNA polymerases beta chain signature. 1082 1094 - T 14-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LH59_27975 7e4692e516fabffca8167ea91c0d3afd 1370 Gene3D G3DSA:2.40.270.10 1054 1270 1.1E-81 T 14-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LH59_27975 7e4692e516fabffca8167ea91c0d3afd 1370 Gene3D G3DSA:2.40.270.10 796 838 1.2E-6 T 14-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LH59_27975 7e4692e516fabffca8167ea91c0d3afd 1370 Pfam PF10385 RNA polymerase beta subunit external 1 domain 597 662 3.4E-25 T 14-10-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LH59_02745 bab2e3f81a96421b9542dfedb0e5bc4c 507 PIRSF PIRSF000538 4 507 4.6E-176 T 14-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 LH59_02745 bab2e3f81a96421b9542dfedb0e5bc4c 507 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 7 252 1.4E-77 T 14-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 LH59_02745 bab2e3f81a96421b9542dfedb0e5bc4c 507 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 136 148 - T 14-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 LH59_02745 bab2e3f81a96421b9542dfedb0e5bc4c 507 Hamap MF_00186 Glycerol kinase [glpK]. 4 503 56.701 T 14-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 LH59_02745 bab2e3f81a96421b9542dfedb0e5bc4c 507 Gene3D G3DSA:3.30.420.40 5 253 3.9E-105 T 14-10-2018 LH59_02745 bab2e3f81a96421b9542dfedb0e5bc4c 507 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 261 456 8.0E-62 T 14-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 LH59_02745 bab2e3f81a96421b9542dfedb0e5bc4c 507 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 368 388 - T 14-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 LH59_02745 bab2e3f81a96421b9542dfedb0e5bc4c 507 Gene3D G3DSA:3.30.420.40 254 506 1.7E-89 T 14-10-2018 LH59_02745 bab2e3f81a96421b9542dfedb0e5bc4c 507 SUPERFAMILY SSF53067 6 255 6.22E-93 T 14-10-2018 LH59_02745 bab2e3f81a96421b9542dfedb0e5bc4c 507 SUPERFAMILY SSF53067 255 502 1.68E-81 T 14-10-2018 LH59_02745 bab2e3f81a96421b9542dfedb0e5bc4c 507 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 6 502 7.8E-214 T 14-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 LH59_12210 626eec77122ec3f60397890f5a34f690 433 Hamap MF_01202 D-amino acid dehydrogenase [dadA]. 1 411 50.144 T 14-10-2018 IPR023080 D-amino acid dehydrogenase DadA GO:0008718|GO:0019478|GO:0055114 LH59_12210 626eec77122ec3f60397890f5a34f690 433 SUPERFAMILY SSF51905 1 420 9.45E-58 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_12210 626eec77122ec3f60397890f5a34f690 433 Gene3D G3DSA:3.50.50.60 100 405 6.4E-56 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_12210 626eec77122ec3f60397890f5a34f690 433 Gene3D G3DSA:3.30.9.10 134 362 6.4E-56 T 14-10-2018 LH59_12210 626eec77122ec3f60397890f5a34f690 433 Pfam PF01266 FAD dependent oxidoreductase 2 397 7.6E-77 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 LH59_12210 626eec77122ec3f60397890f5a34f690 433 SUPERFAMILY SSF54373 270 360 6.93E-18 T 14-10-2018 LH59_12210 626eec77122ec3f60397890f5a34f690 433 Gene3D G3DSA:3.50.50.60 1 73 7.6E-14 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_27945 f76dfd2b89e1b97b793caad79abcba8e 238 Gene3D G3DSA:3.40.50.2300 1 127 7.3E-32 T 14-10-2018 LH59_27945 f76dfd2b89e1b97b793caad79abcba8e 238 Pfam PF00072 Response regulator receiver domain 6 113 5.4E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_27945 f76dfd2b89e1b97b793caad79abcba8e 238 SMART SM00862 148 224 1.9E-16 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_27945 f76dfd2b89e1b97b793caad79abcba8e 238 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 224 1.7E-15 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_27945 f76dfd2b89e1b97b793caad79abcba8e 238 Gene3D G3DSA:1.10.10.10 128 228 2.5E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_27945 f76dfd2b89e1b97b793caad79abcba8e 238 SMART SM00448 1 113 2.9E-34 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_27945 f76dfd2b89e1b97b793caad79abcba8e 238 SUPERFAMILY SSF52172 2 186 1.57E-35 T 14-10-2018 IPR011006 CheY-like superfamily LH59_05830 8c7c6cf2ce25c4ab031dd0c48fca4363 708 Pfam PF07715 TonB-dependent Receptor Plug Domain 84 172 2.4E-6 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_05830 8c7c6cf2ce25c4ab031dd0c48fca4363 708 Gene3D G3DSA:2.170.130.10 58 177 1.7E-8 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily LH59_05830 8c7c6cf2ce25c4ab031dd0c48fca4363 708 SUPERFAMILY SSF56935 28 708 4.71E-87 T 14-10-2018 LH59_05830 8c7c6cf2ce25c4ab031dd0c48fca4363 708 Pfam PF00593 TonB dependent receptor 243 707 4.7E-38 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_05830 8c7c6cf2ce25c4ab031dd0c48fca4363 708 Gene3D G3DSA:2.40.170.20 187 708 2.1E-66 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_08620 a9c2294ef645bf55be005e46ba08eec7 141 ProSitePatterns PS01213 Protozoan/cyanobacterial globins signature. 67 91 - T 14-10-2018 IPR019795 Globin, bacterial-like, conserved site GO:0015671|GO:0019825 LH59_08620 a9c2294ef645bf55be005e46ba08eec7 141 Pfam PF01152 Bacterial-like globin 18 137 1.0E-40 T 14-10-2018 IPR001486 Truncated hemoglobin GO:0019825 LH59_08620 a9c2294ef645bf55be005e46ba08eec7 141 SUPERFAMILY SSF46458 18 139 7.81E-35 T 14-10-2018 IPR009050 Globin-like superfamily LH59_08620 a9c2294ef645bf55be005e46ba08eec7 141 Gene3D G3DSA:1.10.490.10 13 140 8.3E-42 T 14-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 LH59_20570 4ade1a44eef02cf0a26ec9b5433eda8c 208 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 35 125 3.9E-16 T 14-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 LH59_20570 4ade1a44eef02cf0a26ec9b5433eda8c 208 TIGRFAM TIGR04025 PPOX_FMN_DR2398: pyridoxamine 5'-phosphate oxidase, FMN-binding family 14 208 3.2E-84 T 14-10-2018 IPR024029 Pyridoxamine 5-phosphate oxidase, FMN-dependent LH59_20570 4ade1a44eef02cf0a26ec9b5433eda8c 208 Gene3D G3DSA:2.30.110.10 34 162 5.7E-24 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 LH59_20570 4ade1a44eef02cf0a26ec9b5433eda8c 208 SUPERFAMILY SSF50475 31 176 1.02E-22 T 14-10-2018 LH59_17085 7b40e59fde06f32b9eb643d8a7488354 507 Gene3D G3DSA:3.30.930.10 160 504 1.5E-128 T 14-10-2018 LH59_17085 7b40e59fde06f32b9eb643d8a7488354 507 Gene3D G3DSA:2.40.50.140 14 152 4.4E-43 T 14-10-2018 LH59_17085 7b40e59fde06f32b9eb643d8a7488354 507 Pfam PF01336 OB-fold nucleic acid binding domain 67 141 4.0E-16 T 14-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 LH59_17085 7b40e59fde06f32b9eb643d8a7488354 507 SUPERFAMILY SSF55681 160 504 7.74E-116 T 14-10-2018 LH59_17085 7b40e59fde06f32b9eb643d8a7488354 507 Pfam PF00152 tRNA synthetases class II (D, K and N) 160 503 2.8E-82 T 14-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 LH59_17085 7b40e59fde06f32b9eb643d8a7488354 507 PRINTS PR00982 Lysyl-tRNA synthetase signature 388 404 1.3E-38 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 LH59_17085 7b40e59fde06f32b9eb643d8a7488354 507 PRINTS PR00982 Lysyl-tRNA synthetase signature 260 277 1.3E-38 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 LH59_17085 7b40e59fde06f32b9eb643d8a7488354 507 PRINTS PR00982 Lysyl-tRNA synthetase signature 242 255 1.3E-38 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 LH59_17085 7b40e59fde06f32b9eb643d8a7488354 507 PRINTS PR00982 Lysyl-tRNA synthetase signature 213 229 1.3E-38 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 LH59_17085 7b40e59fde06f32b9eb643d8a7488354 507 PRINTS PR00982 Lysyl-tRNA synthetase signature 197 207 1.3E-38 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 LH59_17085 7b40e59fde06f32b9eb643d8a7488354 507 SUPERFAMILY SSF50249 12 153 1.45E-43 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_17085 7b40e59fde06f32b9eb643d8a7488354 507 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 15 505 1.9E-192 T 14-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 LH59_17085 7b40e59fde06f32b9eb643d8a7488354 507 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 20 506 43.516 T 14-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 LH59_16030 1a01bdd27b258533c65cc4eef32f183b 305 Gene3D G3DSA:3.40.190.10 163 268 2.8E-71 T 14-10-2018 LH59_16030 1a01bdd27b258533c65cc4eef32f183b 305 Gene3D G3DSA:3.40.190.10 90 291 2.8E-71 T 14-10-2018 LH59_16030 1a01bdd27b258533c65cc4eef32f183b 305 Pfam PF03466 LysR substrate binding domain 88 292 1.7E-34 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_16030 1a01bdd27b258533c65cc4eef32f183b 305 SUPERFAMILY SSF46785 6 111 4.14E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_16030 1a01bdd27b258533c65cc4eef32f183b 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 3.1E-15 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_16030 1a01bdd27b258533c65cc4eef32f183b 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 5.7E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_16030 1a01bdd27b258533c65cc4eef32f183b 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 5.7E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_16030 1a01bdd27b258533c65cc4eef32f183b 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 5.7E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_16030 1a01bdd27b258533c65cc4eef32f183b 305 SUPERFAMILY SSF53850 88 296 1.29E-36 T 14-10-2018 LH59_16030 1a01bdd27b258533c65cc4eef32f183b 305 Gene3D G3DSA:1.10.10.10 1 89 7.2E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_03040 dcb56b410c263c73c954cbdf79e85179 133 Pfam PF03652 Holliday junction resolvase 5 129 6.6E-35 T 14-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 LH59_03040 dcb56b410c263c73c954cbdf79e85179 133 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 7 128 4.6E-29 T 14-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 LH59_03040 dcb56b410c263c73c954cbdf79e85179 133 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 4 131 21.068 T 14-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 LH59_03040 dcb56b410c263c73c954cbdf79e85179 133 SUPERFAMILY SSF53098 5 129 2.28E-33 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily LH59_03040 dcb56b410c263c73c954cbdf79e85179 133 SMART SM00732 4 104 1.9E-28 T 14-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 LH59_03040 dcb56b410c263c73c954cbdf79e85179 133 Gene3D G3DSA:3.30.420.140 3 130 3.2E-36 T 14-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 LH59_10170 4908162a438ca157216fe1a1fd58e140 360 SUPERFAMILY SSF49503 29 181 9.84E-40 T 14-10-2018 IPR008972 Cupredoxin LH59_10170 4908162a438ca157216fe1a1fd58e140 360 SUPERFAMILY SSF49503 185 353 9.4E-74 T 14-10-2018 IPR008972 Cupredoxin LH59_10170 4908162a438ca157216fe1a1fd58e140 360 TIGRFAM TIGR02376 Cu_nitrite_red: nitrite reductase, copper-containing 31 355 1.2E-161 T 14-10-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 LH59_10170 4908162a438ca157216fe1a1fd58e140 360 Gene3D G3DSA:2.60.40.420 26 176 1.7E-46 T 14-10-2018 IPR008972 Cupredoxin LH59_10170 4908162a438ca157216fe1a1fd58e140 360 PRINTS PR00695 Copper containing nitrite reductase signature 116 135 3.4E-61 T 14-10-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 LH59_10170 4908162a438ca157216fe1a1fd58e140 360 PRINTS PR00695 Copper containing nitrite reductase signature 54 72 3.4E-61 T 14-10-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 LH59_10170 4908162a438ca157216fe1a1fd58e140 360 PRINTS PR00695 Copper containing nitrite reductase signature 99 116 3.4E-61 T 14-10-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 LH59_10170 4908162a438ca157216fe1a1fd58e140 360 PRINTS PR00695 Copper containing nitrite reductase signature 141 156 3.4E-61 T 14-10-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 LH59_10170 4908162a438ca157216fe1a1fd58e140 360 PRINTS PR00695 Copper containing nitrite reductase signature 81 97 3.4E-61 T 14-10-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 LH59_10170 4908162a438ca157216fe1a1fd58e140 360 PRINTS PR00695 Copper containing nitrite reductase signature 159 175 3.4E-61 T 14-10-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 LH59_10170 4908162a438ca157216fe1a1fd58e140 360 Pfam PF07732 Multicopper oxidase 69 177 8.8E-14 T 14-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 LH59_10170 4908162a438ca157216fe1a1fd58e140 360 Pfam PF00394 Multicopper oxidase 193 344 8.1E-20 T 14-10-2018 IPR001117 Multicopper oxidase, type 1 GO:0055114 LH59_10170 4908162a438ca157216fe1a1fd58e140 360 Gene3D G3DSA:2.60.40.420 177 357 2.1E-53 T 14-10-2018 IPR008972 Cupredoxin LH59_11660 b6a2f1d7e15fbe6a9c76e4647d60d914 186 Pfam PF01765 Ribosome recycling factor 21 184 3.8E-61 T 14-10-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 LH59_11660 b6a2f1d7e15fbe6a9c76e4647d60d914 186 Gene3D G3DSA:1.10.132.20 13 183 1.1E-63 T 14-10-2018 LH59_11660 b6a2f1d7e15fbe6a9c76e4647d60d914 186 Hamap MF_00040 Ribosome-recycling factor [frr]. 4 186 26.756 T 14-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 LH59_11660 b6a2f1d7e15fbe6a9c76e4647d60d914 186 Gene3D G3DSA:3.30.1360.40 32 106 1.1E-63 T 14-10-2018 LH59_11660 b6a2f1d7e15fbe6a9c76e4647d60d914 186 SUPERFAMILY SSF55194 5 185 2.49E-68 T 14-10-2018 IPR036191 RRF superfamily Reactome: R-HSA-5419276 LH59_11660 b6a2f1d7e15fbe6a9c76e4647d60d914 186 TIGRFAM TIGR00496 frr: ribosome recycling factor 12 186 7.4E-68 T 14-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 LH59_10395 5bd1ac554219168ddc8cbd993221a09b 312 SUPERFAMILY SSF48452 153 285 1.14E-9 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_10395 5bd1ac554219168ddc8cbd993221a09b 312 Gene3D G3DSA:1.25.40.10 148 286 3.3E-17 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_10395 5bd1ac554219168ddc8cbd993221a09b 312 TIGRFAM TIGR03142 cytochro_ccmI: cytochrome c-type biogenesis protein CcmI 3 118 9.3E-23 T 14-10-2018 IPR017560 Cytochrome c-type biogenesis protein CcmI LH59_08700 ffd6c73d8d8b4dcd9a179084600dcdd0 452 Gene3D G3DSA:3.40.630.30 305 452 4.9E-38 T 14-10-2018 LH59_08700 ffd6c73d8d8b4dcd9a179084600dcdd0 452 Pfam PF00696 Amino acid kinase family 39 269 2.6E-29 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 LH59_08700 ffd6c73d8d8b4dcd9a179084600dcdd0 452 Gene3D G3DSA:3.40.1160.10 20 304 2.2E-83 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily LH59_08700 ffd6c73d8d8b4dcd9a179084600dcdd0 452 Pfam PF00583 Acetyltransferase (GNAT) family 346 423 9.3E-9 T 14-10-2018 IPR000182 GNAT domain LH59_08700 ffd6c73d8d8b4dcd9a179084600dcdd0 452 SUPERFAMILY SSF55729 308 429 2.87E-21 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_08700 ffd6c73d8d8b4dcd9a179084600dcdd0 452 Hamap MF_01105 Amino-acid acetyltransferase [argA]. 1 452 193.274 T 14-10-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 LH59_08700 ffd6c73d8d8b4dcd9a179084600dcdd0 452 PIRSF PIRSF000423 12 452 1.3E-182 T 14-10-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 LH59_08700 ffd6c73d8d8b4dcd9a179084600dcdd0 452 TIGRFAM TIGR01890 N-Ac-Glu-synth: amino-acid N-acetyltransferase 22 452 5.1E-176 T 14-10-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 LH59_08700 ffd6c73d8d8b4dcd9a179084600dcdd0 452 SUPERFAMILY SSF53633 19 303 1.23E-59 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily LH59_10305 c9b898841014cd5956cc8d2ccbb7e118 100 Pfam PF13560 Helix-turn-helix domain 45 86 9.2E-7 T 14-10-2018 LH59_10305 c9b898841014cd5956cc8d2ccbb7e118 100 Gene3D G3DSA:1.10.260.40 10 97 1.0E-15 T 14-10-2018 LH59_10305 c9b898841014cd5956cc8d2ccbb7e118 100 SUPERFAMILY SSF47413 44 97 3.58E-10 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 LH59_25335 6a41b9f3483daef032027ae4b2317405 313 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 35 43 5.6E-14 T 14-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 LH59_25335 6a41b9f3483daef032027ae4b2317405 313 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 61 72 5.6E-14 T 14-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 LH59_25335 6a41b9f3483daef032027ae4b2317405 313 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 105 119 5.6E-14 T 14-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 LH59_25335 6a41b9f3483daef032027ae4b2317405 313 PIRSF PIRSF006431 1 313 1.3E-137 T 14-10-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 LH59_25335 6a41b9f3483daef032027ae4b2317405 313 Pfam PF00561 alpha/beta hydrolase fold 36 293 9.7E-31 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_25335 6a41b9f3483daef032027ae4b2317405 313 SUPERFAMILY SSF53474 2 304 2.06E-65 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_25335 6a41b9f3483daef032027ae4b2317405 313 Gene3D G3DSA:3.40.50.1820 1 313 5.6E-106 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_25335 6a41b9f3483daef032027ae4b2317405 313 TIGRFAM TIGR01249 pro_imino_pep_1: prolyl aminopeptidase 7 310 1.1E-126 T 14-10-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 LH59_03490 d90d9e0889af30238f33245c57d2025f 423 SUPERFAMILY SSF82171 172 417 2.55E-13 T 14-10-2018 LH59_03490 d90d9e0889af30238f33245c57d2025f 423 Gene3D G3DSA:2.120.10.30 239 419 6.4E-7 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like LH59_21430 c95e1dd950b73ab3b3a8e4a0badf88ce 285 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 280 3.7E-26 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_21430 c95e1dd950b73ab3b3a8e4a0badf88ce 285 SUPERFAMILY SSF161098 89 272 3.79E-41 T 14-10-2018 IPR035906 MetI-like superfamily LH59_21430 c95e1dd950b73ab3b3a8e4a0badf88ce 285 Gene3D G3DSA:1.10.3720.10 86 279 8.4E-35 T 14-10-2018 IPR035906 MetI-like superfamily LH59_22380 06222099db5ec6a833ed9ffa5743695d 258 Pfam PF00005 ABC transporter 23 180 2.3E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_22380 06222099db5ec6a833ed9ffa5743695d 258 SMART SM00382 31 229 3.7E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_22380 06222099db5ec6a833ed9ffa5743695d 258 PIRSF PIRSF037116 1 258 2.0E-135 T 14-10-2018 IPR012700 Phosphonate C-P lyase system, PhnK LH59_22380 06222099db5ec6a833ed9ffa5743695d 258 TIGRFAM TIGR02323 CP_lyasePhnK: phosphonate C-P lyase system protein PhnK 4 256 1.2E-112 T 14-10-2018 IPR012700 Phosphonate C-P lyase system, PhnK LH59_22380 06222099db5ec6a833ed9ffa5743695d 258 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_22380 06222099db5ec6a833ed9ffa5743695d 258 Gene3D G3DSA:3.40.50.300 5 258 2.5E-64 T 14-10-2018 LH59_22380 06222099db5ec6a833ed9ffa5743695d 258 SUPERFAMILY SSF52540 4 254 3.39E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_24455 7b0a4ea2cdd83981963a3a3f1774a703 358 SMART SM00962 153 357 4.8E-103 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 LH59_24455 7b0a4ea2cdd83981963a3a3f1774a703 358 Pfam PF00448 SRP54-type protein, GTPase domain 154 356 1.7E-65 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 LH59_24455 7b0a4ea2cdd83981963a3a3f1774a703 358 SUPERFAMILY SSF47364 58 132 7.59E-18 T 14-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 LH59_24455 7b0a4ea2cdd83981963a3a3f1774a703 358 Gene3D G3DSA:3.40.50.300 150 345 3.3E-101 T 14-10-2018 LH59_24455 7b0a4ea2cdd83981963a3a3f1774a703 358 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 82 357 56.711 T 14-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 LH59_24455 7b0a4ea2cdd83981963a3a3f1774a703 358 SMART SM00963 63 139 4.1E-16 T 14-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 LH59_24455 7b0a4ea2cdd83981963a3a3f1774a703 358 Gene3D G3DSA:1.20.120.140 61 355 3.3E-101 T 14-10-2018 LH59_24455 7b0a4ea2cdd83981963a3a3f1774a703 358 SMART SM00382 152 330 4.0E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_24455 7b0a4ea2cdd83981963a3a3f1774a703 358 SUPERFAMILY SSF52540 149 356 1.15E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_24455 7b0a4ea2cdd83981963a3a3f1774a703 358 Pfam PF02881 SRP54-type protein, helical bundle domain 73 133 1.1E-9 T 14-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 LH59_24455 7b0a4ea2cdd83981963a3a3f1774a703 358 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 82 355 1.2E-94 T 14-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 LH59_28000 1044b1b101d2db242c2be4e16a7a7394 177 SUPERFAMILY SSF50104 121 176 8.53E-20 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily LH59_28000 1044b1b101d2db242c2be4e16a7a7394 177 Gene3D G3DSA:2.30.30.30 120 176 7.1E-27 T 14-10-2018 IPR014722 Ribosomal protein L2, domain 2 LH59_28000 1044b1b101d2db242c2be4e16a7a7394 177 SMART SM00739 123 150 4.8E-6 T 14-10-2018 IPR005824 KOW LH59_28000 1044b1b101d2db242c2be4e16a7a7394 177 ProSitePatterns PS01014 Transcription termination factor nusG signature. 160 169 - T 14-10-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site LH59_28000 1044b1b101d2db242c2be4e16a7a7394 177 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 5 176 1.7E-69 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 LH59_28000 1044b1b101d2db242c2be4e16a7a7394 177 Pfam PF02357 Transcription termination factor nusG 3 108 2.7E-27 T 14-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 LH59_28000 1044b1b101d2db242c2be4e16a7a7394 177 Gene3D G3DSA:3.30.70.940 1 119 2.1E-47 T 14-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 LH59_28000 1044b1b101d2db242c2be4e16a7a7394 177 PRINTS PR00338 Transcription termination factor NUSG signature 153 169 1.6E-20 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 LH59_28000 1044b1b101d2db242c2be4e16a7a7394 177 PRINTS PR00338 Transcription termination factor NUSG signature 57 69 1.6E-20 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 LH59_28000 1044b1b101d2db242c2be4e16a7a7394 177 PRINTS PR00338 Transcription termination factor NUSG signature 135 150 1.6E-20 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 LH59_28000 1044b1b101d2db242c2be4e16a7a7394 177 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 2 177 25.873 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 LH59_28000 1044b1b101d2db242c2be4e16a7a7394 177 Pfam PF00467 KOW motif 126 158 2.6E-7 T 14-10-2018 IPR005824 KOW LH59_28000 1044b1b101d2db242c2be4e16a7a7394 177 SUPERFAMILY SSF82679 3 113 2.22E-38 T 14-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 LH59_28000 1044b1b101d2db242c2be4e16a7a7394 177 SMART SM00738 2 111 5.5E-48 T 14-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 LH59_13065 7092b23991bff7d2f6982a5146798be4 535 Pfam PF00005 ABC transporter 334 464 3.6E-23 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_13065 7092b23991bff7d2f6982a5146798be4 535 ProSitePatterns PS00211 ABC transporters family signature. 436 450 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_13065 7092b23991bff7d2f6982a5146798be4 535 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_13065 7092b23991bff7d2f6982a5146798be4 535 SMART SM00382 342 509 8.3E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_13065 7092b23991bff7d2f6982a5146798be4 535 SMART SM00382 17 219 2.8E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_13065 7092b23991bff7d2f6982a5146798be4 535 Gene3D G3DSA:3.40.50.300 1 272 2.9E-54 T 14-10-2018 LH59_13065 7092b23991bff7d2f6982a5146798be4 535 SUPERFAMILY SSF52540 294 516 1.88E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_13065 7092b23991bff7d2f6982a5146798be4 535 Pfam PF00005 ABC transporter 9 173 5.2E-20 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_13065 7092b23991bff7d2f6982a5146798be4 535 Gene3D G3DSA:3.40.50.300 273 534 1.2E-49 T 14-10-2018 LH59_13065 7092b23991bff7d2f6982a5146798be4 535 Pfam PF12848 ABC transporter 212 294 1.6E-24 T 14-10-2018 IPR032781 ABC-transporter extension domain LH59_13065 7092b23991bff7d2f6982a5146798be4 535 SUPERFAMILY SSF52540 5 243 4.99E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_10095 f1af4d0f137333245fe0b7cb2e802e37 209 Gene3D G3DSA:3.40.30.10 1 83 2.7E-24 T 14-10-2018 LH59_10095 f1af4d0f137333245fe0b7cb2e802e37 209 SUPERFAMILY SSF47616 76 201 9.47E-24 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily LH59_10095 f1af4d0f137333245fe0b7cb2e802e37 209 Pfam PF13410 Glutathione S-transferase, C-terminal domain 131 189 1.2E-6 T 14-10-2018 LH59_10095 f1af4d0f137333245fe0b7cb2e802e37 209 Gene3D G3DSA:1.20.1050.10 88 197 1.1E-23 T 14-10-2018 LH59_10095 f1af4d0f137333245fe0b7cb2e802e37 209 Pfam PF13417 Glutathione S-transferase, N-terminal domain 9 83 6.0E-15 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 LH59_10095 f1af4d0f137333245fe0b7cb2e802e37 209 SUPERFAMILY SSF52833 2 89 4.49E-25 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_24300 2632e357dd101d486eec1eee8a386a0c 546 Hamap MF_00600 60 kDa chaperonin [groL]. 2 544 41.506 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 LH59_24300 2632e357dd101d486eec1eee8a386a0c 546 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 526 1.1E-255 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 LH59_24300 2632e357dd101d486eec1eee8a386a0c 546 PRINTS PR00298 60kDa chaperonin signature 83 110 5.5E-74 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 LH59_24300 2632e357dd101d486eec1eee8a386a0c 546 PRINTS PR00298 60kDa chaperonin signature 27 53 5.5E-74 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 LH59_24300 2632e357dd101d486eec1eee8a386a0c 546 PRINTS PR00298 60kDa chaperonin signature 268 291 5.5E-74 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 LH59_24300 2632e357dd101d486eec1eee8a386a0c 546 PRINTS PR00298 60kDa chaperonin signature 350 375 5.5E-74 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 LH59_24300 2632e357dd101d486eec1eee8a386a0c 546 PRINTS PR00298 60kDa chaperonin signature 398 419 5.5E-74 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 LH59_24300 2632e357dd101d486eec1eee8a386a0c 546 Gene3D G3DSA:3.30.260.10 136 410 5.8E-238 T 14-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily LH59_24300 2632e357dd101d486eec1eee8a386a0c 546 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 522 3.5E-98 T 14-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 LH59_24300 2632e357dd101d486eec1eee8a386a0c 546 SUPERFAMILY SSF54849 137 203 7.33E-25 T 14-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily LH59_24300 2632e357dd101d486eec1eee8a386a0c 546 Gene3D G3DSA:3.50.7.10 192 372 5.8E-238 T 14-10-2018 IPR027409 GroEL-like apical domain superfamily LH59_24300 2632e357dd101d486eec1eee8a386a0c 546 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 14-10-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 LH59_24300 2632e357dd101d486eec1eee8a386a0c 546 SUPERFAMILY SSF48592 7 521 3.08E-76 T 14-10-2018 IPR027413 GroEL-like equatorial domain superfamily LH59_24300 2632e357dd101d486eec1eee8a386a0c 546 Gene3D G3DSA:1.10.560.10 8 521 5.8E-238 T 14-10-2018 IPR027413 GroEL-like equatorial domain superfamily LH59_24300 2632e357dd101d486eec1eee8a386a0c 546 SUPERFAMILY SSF52029 184 376 3.89E-83 T 14-10-2018 IPR027409 GroEL-like apical domain superfamily LH59_11855 9841523d6b270bb953a0a595af7fb3d6 316 SUPERFAMILY SSF52768 11 315 5.94E-75 T 14-10-2018 IPR023696 Ureohydrolase domain superfamily LH59_11855 9841523d6b270bb953a0a595af7fb3d6 316 PRINTS PR00116 Arginase signature 241 270 4.2E-5 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 LH59_11855 9841523d6b270bb953a0a595af7fb3d6 316 PRINTS PR00116 Arginase signature 122 137 4.2E-5 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 LH59_11855 9841523d6b270bb953a0a595af7fb3d6 316 Pfam PF00491 Arginase family 44 313 1.2E-57 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 LH59_11855 9841523d6b270bb953a0a595af7fb3d6 316 TIGRFAM TIGR01227 hutG: formimidoylglutamase 11 314 5.8E-85 T 14-10-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 LH59_11855 9841523d6b270bb953a0a595af7fb3d6 316 Hamap MF_00737 Formimidoylglutamase [hutG]. 6 315 40.827 T 14-10-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 LH59_11855 9841523d6b270bb953a0a595af7fb3d6 316 Gene3D G3DSA:3.40.800.10 2 316 2.2E-103 T 14-10-2018 LH59_11855 9841523d6b270bb953a0a595af7fb3d6 316 PIRSF PIRSF036979 34 316 7.9E-27 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 LH59_11855 9841523d6b270bb953a0a595af7fb3d6 316 ProSitePatterns PS01053 Arginase family signature. 244 265 - T 14-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 LH59_04450 16dfadbbb47335bfad5e4cb003a0f314 507 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 327 488 2.7E-46 T 14-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 LH59_04450 16dfadbbb47335bfad5e4cb003a0f314 507 Gene3D G3DSA:3.20.130.10 305 489 1.8E-58 T 14-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 LH59_04450 16dfadbbb47335bfad5e4cb003a0f314 507 SUPERFAMILY SSF117457 320 488 3.66E-62 T 14-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 LH59_04450 16dfadbbb47335bfad5e4cb003a0f314 507 PIRSF PIRSF001394 1 507 3.6E-210 T 14-10-2018 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 LH59_04450 16dfadbbb47335bfad5e4cb003a0f314 507 Pfam PF05681 Fumarate hydratase (Fumerase) 12 285 5.9E-99 T 14-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 LH59_04450 16dfadbbb47335bfad5e4cb003a0f314 507 Pfam PF05683 Fumarase C-terminus 289 490 2.2E-81 T 14-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 LH59_04450 16dfadbbb47335bfad5e4cb003a0f314 507 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 14 285 4.7E-63 T 14-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 LH59_26445 1fce6a787a62d15663f114d3f2d9c431 445 Gene3D G3DSA:3.30.70.1170 188 243 1.4E-15 T 14-10-2018 LH59_26445 1fce6a787a62d15663f114d3f2d9c431 445 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 331 342 - T 14-10-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 LH59_26445 1fce6a787a62d15663f114d3f2d9c431 445 SUPERFAMILY SSF53335 157 443 3.72E-66 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_26445 1fce6a787a62d15663f114d3f2d9c431 445 Pfam PF01189 16S rRNA methyltransferase RsmB/F 254 441 1.0E-48 T 14-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 LH59_26445 1fce6a787a62d15663f114d3f2d9c431 445 Gene3D G3DSA:1.10.940.10 18 160 4.4E-6 T 14-10-2018 IPR035926 NusB-like superfamily LH59_26445 1fce6a787a62d15663f114d3f2d9c431 445 SUPERFAMILY SSF48013 28 164 8.5E-11 T 14-10-2018 IPR035926 NusB-like superfamily LH59_26445 1fce6a787a62d15663f114d3f2d9c431 445 Gene3D G3DSA:3.40.50.150 244 444 6.3E-56 T 14-10-2018 LH59_26445 1fce6a787a62d15663f114d3f2d9c431 445 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 264 274 1.3E-22 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase LH59_26445 1fce6a787a62d15663f114d3f2d9c431 445 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 426 443 1.3E-22 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase LH59_26445 1fce6a787a62d15663f114d3f2d9c431 445 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 382 398 1.3E-22 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase LH59_26445 1fce6a787a62d15663f114d3f2d9c431 445 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 235 249 1.3E-22 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase LH59_26445 1fce6a787a62d15663f114d3f2d9c431 445 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 332 344 1.3E-22 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase LH59_26445 1fce6a787a62d15663f114d3f2d9c431 445 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 108 444 1.9E-84 T 14-10-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 LH59_26445 1fce6a787a62d15663f114d3f2d9c431 445 Gene3D G3DSA:1.10.287.730 161 185 8.8E-6 T 14-10-2018 LH59_02530 20f13c17fa50cee1d8837737db7065c2 269 Hamap MF_00443 Thiazole synthase [thiG]. 6 262 41.934 T 14-10-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 LH59_02530 20f13c17fa50cee1d8837737db7065c2 269 SUPERFAMILY SSF110399 5 247 3.92E-89 T 14-10-2018 LH59_02530 20f13c17fa50cee1d8837737db7065c2 269 Gene3D G3DSA:3.20.20.70 1 262 6.1E-116 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_02530 20f13c17fa50cee1d8837737db7065c2 269 Pfam PF05690 Thiazole biosynthesis protein ThiG 9 255 6.8E-106 T 14-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 LH59_05425 707055c8b33b592b3592c3f6ad7debc5 719 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 346 352 - T 14-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 LH59_05425 707055c8b33b592b3592c3f6ad7debc5 719 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 187 201 2.1E-25 T 14-10-2018 LH59_05425 707055c8b33b592b3592c3f6ad7debc5 719 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 478 489 2.1E-25 T 14-10-2018 LH59_05425 707055c8b33b592b3592c3f6ad7debc5 719 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 553 572 2.1E-25 T 14-10-2018 LH59_05425 707055c8b33b592b3592c3f6ad7debc5 719 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 344 358 2.1E-25 T 14-10-2018 LH59_05425 707055c8b33b592b3592c3f6ad7debc5 719 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 576 588 2.1E-25 T 14-10-2018 LH59_05425 707055c8b33b592b3592c3f6ad7debc5 719 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 500 510 2.1E-25 T 14-10-2018 LH59_05425 707055c8b33b592b3592c3f6ad7debc5 719 SUPERFAMILY SSF81653 155 240 5.89E-17 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 LH59_05425 707055c8b33b592b3592c3f6ad7debc5 719 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 145 365 3.3E-26 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 LH59_05425 707055c8b33b592b3592c3f6ad7debc5 719 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 408 639 1.2E-45 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 LH59_05425 707055c8b33b592b3592c3f6ad7debc5 719 Gene3D G3DSA:3.40.1110.10 356 487 4.6E-46 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 LH59_05425 707055c8b33b592b3592c3f6ad7debc5 719 SUPERFAMILY SSF81665 51 696 1.28E-11 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 LH59_05425 707055c8b33b592b3592c3f6ad7debc5 719 Pfam PF00122 E1-E2 ATPase 155 322 4.0E-28 T 14-10-2018 LH59_05425 707055c8b33b592b3592c3f6ad7debc5 719 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 34 713 0.0 T 14-10-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 LH59_05425 707055c8b33b592b3592c3f6ad7debc5 719 SUPERFAMILY SSF56784 332 596 4.03E-36 T 14-10-2018 IPR036412 HAD-like superfamily LH59_05425 707055c8b33b592b3592c3f6ad7debc5 719 Gene3D G3DSA:2.70.150.20 138 245 4.2E-23 T 14-10-2018 LH59_05425 707055c8b33b592b3592c3f6ad7debc5 719 Pfam PF00702 haloacid dehalogenase-like hydrolase 340 567 4.0E-33 T 14-10-2018 LH59_05425 707055c8b33b592b3592c3f6ad7debc5 719 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 30 717 40.394 T 14-10-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 LH59_24910 915de2722a27941a17aeab13c2d7d7f9 264 Pfam PF14302 Domain of unknown function (DUF4377) 184 259 3.9E-23 T 14-10-2018 IPR025485 Domain of unknown function DUF4377 LH59_24910 915de2722a27941a17aeab13c2d7d7f9 264 Gene3D G3DSA:2.40.128.270 40 170 2.0E-31 T 14-10-2018 IPR038670 HslJ-like superfamily LH59_24910 915de2722a27941a17aeab13c2d7d7f9 264 Pfam PF03724 META domain 44 162 2.2E-19 T 14-10-2018 IPR005184 Domain of unknown function DUF306, Meta/HslJ LH59_07915 fc2cec4f1270fc6eb8ba1b093ec37fb0 43 Pfam PF08085 Entericidin EcnA/B family 21 41 9.7E-10 T 14-10-2018 IPR012556 Entericidin A/B GO:0009636|GO:0016020 LH59_11090 011f9cedf341b186a22d96d9262d9a9f 162 SUPERFAMILY SSF54523 13 124 9.42E-10 T 14-10-2018 LH59_11090 011f9cedf341b186a22d96d9262d9a9f 162 Pfam PF12019 Type II transport protein GspH 47 148 4.5E-5 T 14-10-2018 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 LH59_11090 011f9cedf341b186a22d96d9262d9a9f 162 Pfam PF07963 Prokaryotic N-terminal methylation motif 8 32 2.9E-9 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site LH59_11090 011f9cedf341b186a22d96d9262d9a9f 162 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 11 31 - T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site LH59_11090 011f9cedf341b186a22d96d9262d9a9f 162 TIGRFAM TIGR01708 typeII_sec_gspH: type II secretion system protein H 10 159 4.1E-26 T 14-10-2018 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 LH59_11090 011f9cedf341b186a22d96d9262d9a9f 162 PRINTS PR00885 Bacterial general secretion pathway protein H signature 8 22 5.8E-7 T 14-10-2018 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 LH59_11090 011f9cedf341b186a22d96d9262d9a9f 162 PRINTS PR00885 Bacterial general secretion pathway protein H signature 23 37 5.8E-7 T 14-10-2018 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 LH59_11090 011f9cedf341b186a22d96d9262d9a9f 162 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 11 32 1.0E-8 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site LH59_01865 e872be10b4fcb82dff5b754a10cd576b 318 SUPERFAMILY SSF52283 2 127 1.23E-21 T 14-10-2018 LH59_01865 e872be10b4fcb82dff5b754a10cd576b 318 Gene3D G3DSA:3.40.50.720 2 310 3.3E-116 T 14-10-2018 LH59_01865 e872be10b4fcb82dff5b754a10cd576b 318 SUPERFAMILY SSF51735 107 286 6.81E-51 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_01865 e872be10b4fcb82dff5b754a10cd576b 318 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 313 4.3E-12 T 14-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 LH59_01865 e872be10b4fcb82dff5b754a10cd576b 318 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 114 286 4.5E-53 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 LH59_01865 e872be10b4fcb82dff5b754a10cd576b 318 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 148 175 - T 14-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 LH59_01865 e872be10b4fcb82dff5b754a10cd576b 318 Gene3D G3DSA:3.40.50.720 107 302 3.3E-116 T 14-10-2018 LH59_08230 80f0c69333e8d228310380f351c80476 458 ProSitePatterns PS00163 Fumarate lyases signature. 297 306 - T 14-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 LH59_08230 80f0c69333e8d228310380f351c80476 458 Gene3D G3DSA:1.10.275.10 2 120 7.4E-41 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal LH59_08230 80f0c69333e8d228310380f351c80476 458 Gene3D G3DSA:1.20.200.10 121 449 2.5E-143 T 14-10-2018 LH59_08230 80f0c69333e8d228310380f351c80476 458 Pfam PF00206 Lyase 18 315 9.2E-56 T 14-10-2018 IPR022761 Fumarate lyase, N-terminal LH59_08230 80f0c69333e8d228310380f351c80476 458 Gene3D G3DSA:1.10.40.30 385 448 2.5E-143 T 14-10-2018 LH59_08230 80f0c69333e8d228310380f351c80476 458 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 16 454 2.6E-120 T 14-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 LH59_08230 80f0c69333e8d228310380f351c80476 458 PRINTS PR00149 Fumarate lyase superfamily signature 120 138 3.2E-14 T 14-10-2018 IPR000362 Fumarate lyase family LH59_08230 80f0c69333e8d228310380f351c80476 458 PRINTS PR00149 Fumarate lyase superfamily signature 297 313 3.2E-14 T 14-10-2018 IPR000362 Fumarate lyase family LH59_08230 80f0c69333e8d228310380f351c80476 458 PRINTS PR00149 Fumarate lyase superfamily signature 166 184 3.2E-14 T 14-10-2018 IPR000362 Fumarate lyase family LH59_08230 80f0c69333e8d228310380f351c80476 458 SUPERFAMILY SSF48557 7 450 1.73E-99 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 LH59_08230 80f0c69333e8d228310380f351c80476 458 Pfam PF08328 Adenylosuccinate lyase C-terminal 334 448 7.7E-49 T 14-10-2018 IPR013539 Adenylosuccinate lyase PurB, C-terminal GO:0004018|GO:0006188 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234 LH59_19035 1c4d777dd3f33e5e993dd8b97f9fd5a4 331 PIRSF PIRSF017082 2 330 1.9E-84 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_19035 1c4d777dd3f33e5e993dd8b97f9fd5a4 331 SUPERFAMILY SSF53850 117 290 9.78E-17 T 14-10-2018 LH59_19035 1c4d777dd3f33e5e993dd8b97f9fd5a4 331 Gene3D G3DSA:3.40.190.150 35 320 2.0E-115 T 14-10-2018 LH59_19035 1c4d777dd3f33e5e993dd8b97f9fd5a4 331 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 54 326 5.7E-90 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_19035 1c4d777dd3f33e5e993dd8b97f9fd5a4 331 Gene3D G3DSA:3.40.190.10 132 255 2.0E-115 T 14-10-2018 LH59_27240 df0e773852d5b4243d30aae4ac3b7519 394 Gene3D G3DSA:3.40.710.10 37 287 7.4E-94 T 14-10-2018 LH59_27240 df0e773852d5b4243d30aae4ac3b7519 394 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 43 268 1.4E-81 T 14-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 LH59_27240 df0e773852d5b4243d30aae4ac3b7519 394 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 128 145 2.8E-17 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 LH59_27240 df0e773852d5b4243d30aae4ac3b7519 394 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 155 168 2.8E-17 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 LH59_27240 df0e773852d5b4243d30aae4ac3b7519 394 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 75 86 2.8E-17 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 LH59_27240 df0e773852d5b4243d30aae4ac3b7519 394 Gene3D G3DSA:2.60.410.10 288 378 1.5E-21 T 14-10-2018 IPR037167 D-Ala-D-Ala carboxypeptidase, C-terminal domain superfamily GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 LH59_27240 df0e773852d5b4243d30aae4ac3b7519 394 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 288 378 1.7E-18 T 14-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 LH59_27240 df0e773852d5b4243d30aae4ac3b7519 394 SUPERFAMILY SSF69189 288 380 3.53E-21 T 14-10-2018 IPR015956 Penicillin-binding protein, C-terminal domain superfamily GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 LH59_27240 df0e773852d5b4243d30aae4ac3b7519 394 SMART SM00936 288 378 2.9E-27 T 14-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 LH59_27240 df0e773852d5b4243d30aae4ac3b7519 394 SUPERFAMILY SSF56601 47 288 9.61E-86 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like LH59_02075 8e086c485363973421549b155f5c7397 310 SUPERFAMILY SSF46689 205 252 4.12E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_02075 8e086c485363973421549b155f5c7397 310 SUPERFAMILY SSF46689 258 306 8.06E-7 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_02075 8e086c485363973421549b155f5c7397 310 Pfam PF12833 Helix-turn-helix domain 228 306 3.6E-19 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_02075 8e086c485363973421549b155f5c7397 310 SUPERFAMILY SSF52317 1 187 1.37E-43 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_02075 8e086c485363973421549b155f5c7397 310 Gene3D G3DSA:1.10.10.60 202 308 5.8E-25 T 14-10-2018 LH59_02075 8e086c485363973421549b155f5c7397 310 Gene3D G3DSA:3.40.50.880 1 196 2.4E-56 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_02075 8e086c485363973421549b155f5c7397 310 Pfam PF01965 DJ-1/PfpI family 33 167 2.6E-15 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 LH59_02075 8e086c485363973421549b155f5c7397 310 SMART SM00342 222 305 2.6E-21 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_26030 bb22550a7a8aeff854600790218f93be 568 Gene3D G3DSA:3.90.700.10 350 497 1.7E-144 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 LH59_26030 bb22550a7a8aeff854600790218f93be 568 Gene3D G3DSA:3.50.50.60 9 560 1.7E-144 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_26030 bb22550a7a8aeff854600790218f93be 568 Pfam PF00890 FAD binding domain 11 549 1.3E-92 T 14-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 LH59_26030 bb22550a7a8aeff854600790218f93be 568 SUPERFAMILY SSF51905 4 565 1.66E-39 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_26030 bb22550a7a8aeff854600790218f93be 568 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 1.2E-5 T 14-10-2018 LH59_26030 bb22550a7a8aeff854600790218f93be 568 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 524 539 1.2E-5 T 14-10-2018 LH59_26030 bb22550a7a8aeff854600790218f93be 568 SUPERFAMILY SSF56425 342 508 4.45E-35 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 LH59_12905 a125b0dd1e660e95d6dd23beea622102 362 Gene3D G3DSA:2.40.50.140 293 342 1.8E-20 T 14-10-2018 LH59_12905 a125b0dd1e660e95d6dd23beea622102 362 Pfam PF08402 TOBE domain 280 346 6.0E-9 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 LH59_12905 a125b0dd1e660e95d6dd23beea622102 362 Pfam PF00005 ABC transporter 21 162 8.2E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_12905 a125b0dd1e660e95d6dd23beea622102 362 Gene3D G3DSA:3.40.50.300 1 239 4.1E-75 T 14-10-2018 LH59_12905 a125b0dd1e660e95d6dd23beea622102 362 SMART SM00382 29 212 1.1E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_12905 a125b0dd1e660e95d6dd23beea622102 362 Gene3D G3DSA:2.40.50.100 240 354 1.8E-20 T 14-10-2018 LH59_12905 a125b0dd1e660e95d6dd23beea622102 362 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_12905 a125b0dd1e660e95d6dd23beea622102 362 SUPERFAMILY SSF50331 237 359 4.37E-23 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal LH59_12905 a125b0dd1e660e95d6dd23beea622102 362 SUPERFAMILY SSF52540 4 244 2.66E-86 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_01960 4ec0cfb2b7ad86043e83f875638feb75 221 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 2 220 1.2E-98 T 14-10-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 LH59_01960 4ec0cfb2b7ad86043e83f875638feb75 221 SMART SM00882 6 219 8.5E-66 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 LH59_01960 4ec0cfb2b7ad86043e83f875638feb75 221 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 18 33 - T 14-10-2018 IPR004163 Coenzyme A transferase binding site GO:0008410 Reactome: R-HSA-77108 LH59_01960 4ec0cfb2b7ad86043e83f875638feb75 221 Pfam PF01144 Coenzyme A transferase 9 218 1.7E-60 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 LH59_01960 4ec0cfb2b7ad86043e83f875638feb75 221 SUPERFAMILY SSF100950 7 220 1.4E-71 T 14-10-2018 IPR037171 NagB/RpiA transferase-like LH59_01960 4ec0cfb2b7ad86043e83f875638feb75 221 Gene3D G3DSA:3.40.1080.10 1 218 3.9E-74 T 14-10-2018 LH59_00375 f0260ffedf6d582bd055c16bce31777d 245 SUPERFAMILY SSF52540 3 237 2.84E-75 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_00375 f0260ffedf6d582bd055c16bce31777d 245 SMART SM00382 28 215 1.5E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_00375 f0260ffedf6d582bd055c16bce31777d 245 Gene3D G3DSA:3.40.50.300 1 242 3.8E-76 T 14-10-2018 LH59_00375 f0260ffedf6d582bd055c16bce31777d 245 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_00375 f0260ffedf6d582bd055c16bce31777d 245 Pfam PF00005 ABC transporter 19 167 3.6E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_00375 f0260ffedf6d582bd055c16bce31777d 245 PIRSF PIRSF039085 1 242 7.1E-105 T 14-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 LH59_15775 dfeab0e15e61c4869135ef10da75f566 338 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 1 338 31.276 T 14-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 LH59_15775 dfeab0e15e61c4869135ef10da75f566 338 Pfam PF00072 Response regulator receiver domain 4 98 3.5E-15 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_15775 dfeab0e15e61c4869135ef10da75f566 338 SMART SM00448 1 116 3.8E-10 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_15775 dfeab0e15e61c4869135ef10da75f566 338 SUPERFAMILY SSF52738 154 336 1.18E-59 T 14-10-2018 IPR035909 Methylesterase CheB, C-terminal LH59_15775 dfeab0e15e61c4869135ef10da75f566 338 Gene3D G3DSA:3.40.50.180 146 338 1.0E-62 T 14-10-2018 IPR035909 Methylesterase CheB, C-terminal LH59_15775 dfeab0e15e61c4869135ef10da75f566 338 PIRSF PIRSF000876 1 338 1.7E-97 T 14-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 LH59_15775 dfeab0e15e61c4869135ef10da75f566 338 Pfam PF01339 CheB methylesterase 158 333 4.7E-56 T 14-10-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 LH59_15775 dfeab0e15e61c4869135ef10da75f566 338 Gene3D G3DSA:3.40.50.2300 1 126 6.5E-22 T 14-10-2018 LH59_15775 dfeab0e15e61c4869135ef10da75f566 338 SUPERFAMILY SSF52172 2 102 5.83E-19 T 14-10-2018 IPR011006 CheY-like superfamily LH59_27090 0382583c240d53889826818ea5f5f259 327 Gene3D G3DSA:3.40.190.10 128 252 1.1E-109 T 14-10-2018 LH59_27090 0382583c240d53889826818ea5f5f259 327 SUPERFAMILY SSF53850 115 291 6.51E-8 T 14-10-2018 LH59_27090 0382583c240d53889826818ea5f5f259 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 323 6.1E-83 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_27090 0382583c240d53889826818ea5f5f259 327 Gene3D G3DSA:3.40.190.150 31 317 1.1E-109 T 14-10-2018 LH59_27090 0382583c240d53889826818ea5f5f259 327 PIRSF PIRSF017082 2 327 8.3E-80 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_00105 f0025b456ffaa72fdd831a6bf1931b1d 280 Pfam PF01614 Bacterial transcriptional regulator 139 258 1.3E-12 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal LH59_00105 f0025b456ffaa72fdd831a6bf1931b1d 280 SUPERFAMILY SSF46785 16 85 1.09E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_00105 f0025b456ffaa72fdd831a6bf1931b1d 280 Gene3D G3DSA:3.30.450.40 89 262 3.7E-33 T 14-10-2018 IPR029016 GAF-like domain superfamily LH59_00105 f0025b456ffaa72fdd831a6bf1931b1d 280 Gene3D G3DSA:1.10.10.10 12 81 1.3E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_00105 f0025b456ffaa72fdd831a6bf1931b1d 280 SMART SM00346 13 105 1.0E-11 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_00105 f0025b456ffaa72fdd831a6bf1931b1d 280 Pfam PF09339 IclR helix-turn-helix domain 16 65 2.8E-15 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_00105 f0025b456ffaa72fdd831a6bf1931b1d 280 SUPERFAMILY SSF55781 89 260 1.44E-33 T 14-10-2018 LH59_12805 30ffd18732ecec1892b670535e48d8a8 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 3.5E-21 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_12805 30ffd18732ecec1892b670535e48d8a8 300 SUPERFAMILY SSF46785 3 113 1.93E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_12805 30ffd18732ecec1892b670535e48d8a8 300 Gene3D G3DSA:1.10.10.10 1 87 6.1E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_12805 30ffd18732ecec1892b670535e48d8a8 300 Gene3D G3DSA:3.40.190.290 92 297 1.0E-47 T 14-10-2018 LH59_12805 30ffd18732ecec1892b670535e48d8a8 300 Pfam PF03466 LysR substrate binding domain 90 290 1.3E-48 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_12805 30ffd18732ecec1892b670535e48d8a8 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 9.9E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_12805 30ffd18732ecec1892b670535e48d8a8 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 9.9E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_12805 30ffd18732ecec1892b670535e48d8a8 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 9.9E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_12805 30ffd18732ecec1892b670535e48d8a8 300 SUPERFAMILY SSF53850 92 295 1.58E-48 T 14-10-2018 LH59_15240 5c15bbec1b3be95bbc1abc0db3dfdcdf 332 Pfam PF00691 OmpA family 190 288 1.8E-20 T 14-10-2018 IPR006665 OmpA-like domain LH59_15240 5c15bbec1b3be95bbc1abc0db3dfdcdf 332 SUPERFAMILY SSF103088 179 294 7.32E-31 T 14-10-2018 IPR036737 OmpA-like domain superfamily LH59_15240 5c15bbec1b3be95bbc1abc0db3dfdcdf 332 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 53 81 1.5E-6 T 14-10-2018 IPR025713 Motility protein B, N-terminal domain LH59_15240 5c15bbec1b3be95bbc1abc0db3dfdcdf 332 Gene3D G3DSA:3.30.1330.60 144 301 3.2E-47 T 14-10-2018 IPR036737 OmpA-like domain superfamily LH59_03600 959a568de6036e0bfad1fe537a612a83 1038 SUPERFAMILY SSF82866 784 1009 3.92E-47 T 14-10-2018 LH59_03600 959a568de6036e0bfad1fe537a612a83 1038 SUPERFAMILY SSF82693 40 134 1.57E-25 T 14-10-2018 LH59_03600 959a568de6036e0bfad1fe537a612a83 1038 Gene3D G3DSA:3.30.70.1320 134 325 0.0 T 14-10-2018 LH59_03600 959a568de6036e0bfad1fe537a612a83 1038 Gene3D G3DSA:3.30.70.1430 555 647 0.0 T 14-10-2018 LH59_03600 959a568de6036e0bfad1fe537a612a83 1038 SUPERFAMILY SSF82714 182 264 2.35E-20 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_03600 959a568de6036e0bfad1fe537a612a83 1038 Pfam PF00873 AcrB/AcrD/AcrF family 3 1003 0.0 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_03600 959a568de6036e0bfad1fe537a612a83 1038 Gene3D G3DSA:1.20.1640.10 501 1000 0.0 T 14-10-2018 LH59_03600 959a568de6036e0bfad1fe537a612a83 1038 SUPERFAMILY SSF82866 296 490 9.16E-52 T 14-10-2018 LH59_03600 959a568de6036e0bfad1fe537a612a83 1038 Gene3D G3DSA:3.30.70.1440 648 843 0.0 T 14-10-2018 LH59_03600 959a568de6036e0bfad1fe537a612a83 1038 PRINTS PR00702 Acriflavin resistance protein family signature 437 460 9.0E-79 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_03600 959a568de6036e0bfad1fe537a612a83 1038 PRINTS PR00702 Acriflavin resistance protein family signature 356 377 9.0E-79 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_03600 959a568de6036e0bfad1fe537a612a83 1038 PRINTS PR00702 Acriflavin resistance protein family signature 384 408 9.0E-79 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_03600 959a568de6036e0bfad1fe537a612a83 1038 PRINTS PR00702 Acriflavin resistance protein family signature 540 557 9.0E-79 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_03600 959a568de6036e0bfad1fe537a612a83 1038 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 9.0E-79 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_03600 959a568de6036e0bfad1fe537a612a83 1038 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 9.0E-79 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_03600 959a568de6036e0bfad1fe537a612a83 1038 PRINTS PR00702 Acriflavin resistance protein family signature 462 485 9.0E-79 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_03600 959a568de6036e0bfad1fe537a612a83 1038 PRINTS PR00702 Acriflavin resistance protein family signature 603 617 9.0E-79 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_03600 959a568de6036e0bfad1fe537a612a83 1038 PRINTS PR00702 Acriflavin resistance protein family signature 329 352 9.0E-79 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_03600 959a568de6036e0bfad1fe537a612a83 1038 SUPERFAMILY SSF82693 553 648 1.26E-19 T 14-10-2018 LH59_03600 959a568de6036e0bfad1fe537a612a83 1038 Gene3D G3DSA:3.30.2090.10 178 268 0.0 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_03600 959a568de6036e0bfad1fe537a612a83 1038 Gene3D G3DSA:3.30.2090.10 698 786 0.0 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_03600 959a568de6036e0bfad1fe537a612a83 1038 SUPERFAMILY SSF82714 699 784 3.79E-18 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_03600 959a568de6036e0bfad1fe537a612a83 1038 SUPERFAMILY SSF82693 136 323 1.83E-24 T 14-10-2018 LH59_03600 959a568de6036e0bfad1fe537a612a83 1038 Gene3D G3DSA:1.20.1640.10 10 500 0.0 T 14-10-2018 LH59_03600 959a568de6036e0bfad1fe537a612a83 1038 Gene3D G3DSA:3.30.70.1430 40 794 0.0 T 14-10-2018 LH59_01725 09c760c0fca384db7a75c50c4b8076b4 299 Gene3D G3DSA:3.30.70.20 17 162 3.3E-97 T 14-10-2018 LH59_01725 09c760c0fca384db7a75c50c4b8076b4 299 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 133 144 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site LH59_01725 09c760c0fca384db7a75c50c4b8076b4 299 SUPERFAMILY SSF54862 29 281 2.83E-72 T 14-10-2018 LH59_01725 09c760c0fca384db7a75c50c4b8076b4 299 PIRSF PIRSF036298 1 299 6.3E-153 T 14-10-2018 IPR014603 Formate dehydrogenase iron-sulphur subunit GO:0015944|GO:0045333|GO:0051539 LH59_01725 09c760c0fca384db7a75c50c4b8076b4 299 Gene3D G3DSA:1.20.5.480 247 295 4.0E-12 T 14-10-2018 IPR038384 Formate dehydrogenase, C-terminal domain superfamily LH59_01725 09c760c0fca384db7a75c50c4b8076b4 299 Pfam PF09163 Formate dehydrogenase N, transmembrane 246 289 2.3E-22 T 14-10-2018 IPR015246 Formate dehydrogenase, transmembrane LH59_01725 09c760c0fca384db7a75c50c4b8076b4 299 TIGRFAM TIGR01582 FDH-beta: formate dehydrogenase, beta subunit 7 289 2.9E-141 T 14-10-2018 IPR006470 Formate dehydrogenase iron-sulphur subunit, Proteobacteria GO:0015944|GO:0016021|GO:0045333|GO:0051539 LH59_01725 09c760c0fca384db7a75c50c4b8076b4 299 Gene3D G3DSA:3.30.70.20 27 227 3.3E-97 T 14-10-2018 LH59_01725 09c760c0fca384db7a75c50c4b8076b4 299 Pfam PF13247 4Fe-4S dicluster domain 92 188 9.8E-24 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain LH59_05070 90e5a562e1097bf86572cd150659def1 933 SUPERFAMILY SSF81653 201 302 3.92E-27 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 LH59_05070 90e5a562e1097bf86572cd150659def1 933 Gene3D G3DSA:3.40.1110.10 416 580 3.8E-59 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 LH59_05070 90e5a562e1097bf86572cd150659def1 933 Pfam PF00702 haloacid dehalogenase-like hydrolase 399 688 2.3E-20 T 14-10-2018 LH59_05070 90e5a562e1097bf86572cd150659def1 933 Pfam PF00689 Cation transporting ATPase, C-terminus 757 923 1.9E-16 T 14-10-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 LH59_05070 90e5a562e1097bf86572cd150659def1 933 Gene3D G3DSA:1.20.1110.10 716 837 1.7E-8 T 14-10-2018 LH59_05070 90e5a562e1097bf86572cd150659def1 933 Gene3D G3DSA:1.20.1110.10 300 415 4.1E-26 T 14-10-2018 LH59_05070 90e5a562e1097bf86572cd150659def1 933 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 405 411 - T 14-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 LH59_05070 90e5a562e1097bf86572cd150659def1 933 PRINTS PR01836 Magnesium-transporting ATPase signature 837 858 5.8E-84 T 14-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 LH59_05070 90e5a562e1097bf86572cd150659def1 933 PRINTS PR01836 Magnesium-transporting ATPase signature 316 332 5.8E-84 T 14-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 LH59_05070 90e5a562e1097bf86572cd150659def1 933 PRINTS PR01836 Magnesium-transporting ATPase signature 750 761 5.8E-84 T 14-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 LH59_05070 90e5a562e1097bf86572cd150659def1 933 PRINTS PR01836 Magnesium-transporting ATPase signature 333 352 5.8E-84 T 14-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 LH59_05070 90e5a562e1097bf86572cd150659def1 933 PRINTS PR01836 Magnesium-transporting ATPase signature 732 747 5.8E-84 T 14-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 LH59_05070 90e5a562e1097bf86572cd150659def1 933 PRINTS PR01836 Magnesium-transporting ATPase signature 887 908 5.8E-84 T 14-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 LH59_05070 90e5a562e1097bf86572cd150659def1 933 PRINTS PR01836 Magnesium-transporting ATPase signature 437 450 5.8E-84 T 14-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 LH59_05070 90e5a562e1097bf86572cd150659def1 933 PRINTS PR01836 Magnesium-transporting ATPase signature 802 818 5.8E-84 T 14-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 LH59_05070 90e5a562e1097bf86572cd150659def1 933 PRINTS PR01836 Magnesium-transporting ATPase signature 782 795 5.8E-84 T 14-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 LH59_05070 90e5a562e1097bf86572cd150659def1 933 Gene3D G3DSA:3.40.50.1000 581 715 1.1E-22 T 14-10-2018 IPR023214 HAD superfamily LH59_05070 90e5a562e1097bf86572cd150659def1 933 SUPERFAMILY SSF81665 51 931 5.36E-106 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 LH59_05070 90e5a562e1097bf86572cd150659def1 933 SMART SM00831 52 125 1.3E-4 T 14-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 LH59_05070 90e5a562e1097bf86572cd150659def1 933 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 202 439 5.6E-33 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 LH59_05070 90e5a562e1097bf86572cd150659def1 933 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 642 763 6.8E-30 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 LH59_05070 90e5a562e1097bf86572cd150659def1 933 Pfam PF00690 Cation transporter/ATPase, N-terminus 55 120 4.9E-13 T 14-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 LH59_05070 90e5a562e1097bf86572cd150659def1 933 TIGRFAM TIGR01524 ATPase-IIIB_Mg: magnesium-translocating P-type ATPase 45 933 0.0 T 14-10-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 LH59_05070 90e5a562e1097bf86572cd150659def1 933 Pfam PF00122 E1-E2 ATPase 202 383 6.7E-48 T 14-10-2018 LH59_05070 90e5a562e1097bf86572cd150659def1 933 SUPERFAMILY SSF56784 565 718 6.85E-36 T 14-10-2018 IPR036412 HAD-like superfamily LH59_05070 90e5a562e1097bf86572cd150659def1 933 SUPERFAMILY SSF81660 398 582 1.86E-39 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 LH59_05070 90e5a562e1097bf86572cd150659def1 933 Gene3D G3DSA:2.70.150.10 147 299 9.7E-40 T 14-10-2018 LH59_16595 ad88f1ff5b6b021b8a30904111093273 253 Pfam PF06629 MltA-interacting protein MipA 29 253 1.1E-44 T 14-10-2018 IPR010583 MltA-interacting MipA LH59_01110 8410f1988dbbac1cda1c8b23d2a31808 280 ProDom PD587589 PHOSPHODIESTERASE ICC METALLOPHOSPHOESTERASE CYCLIC REGULATOR LACZ AMP HYDROLASE 3'5'-CYCLIC-NUCLEOTIDE EXPRESSION 206 261 2.0E-21 T 14-10-2018 IPR013622 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA, C-terminal KEGG: 00230+3.1.4.53 LH59_01110 8410f1988dbbac1cda1c8b23d2a31808 280 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 15 261 36.914 T 14-10-2018 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 LH59_01110 8410f1988dbbac1cda1c8b23d2a31808 280 SUPERFAMILY SSF56300 17 263 1.0E-50 T 14-10-2018 LH59_01110 8410f1988dbbac1cda1c8b23d2a31808 280 Pfam PF00149 Calcineurin-like phosphoesterase 18 206 4.0E-14 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 LH59_01110 8410f1988dbbac1cda1c8b23d2a31808 280 Gene3D G3DSA:3.60.21.10 2 277 2.5E-74 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like LH59_17430 69a6ae2f5c8436479e87b097a55e04df 1057 Pfam PF13550 Putative phage tail protein 370 530 2.4E-24 T 14-10-2018 IPR032876 Tip attachment protein J LH59_17430 69a6ae2f5c8436479e87b097a55e04df 1057 Gene3D G3DSA:2.60.40.10 666 761 1.6E-6 T 14-10-2018 IPR013783 Immunoglobulin-like fold LH59_17430 69a6ae2f5c8436479e87b097a55e04df 1057 SUPERFAMILY SSF49265 674 762 1.28E-6 T 14-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 LH59_17430 69a6ae2f5c8436479e87b097a55e04df 1057 Pfam PF09327 Domain of unknown function (DUF1983) 906 982 4.0E-22 T 14-10-2018 IPR015406 Domain of unknown function DUF1983 LH59_20310 acbd2a8d538de48102ba16f9505d0792 321 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 113 131 3.8E-46 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 LH59_20310 acbd2a8d538de48102ba16f9505d0792 321 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 169 182 3.8E-46 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 LH59_20310 acbd2a8d538de48102ba16f9505d0792 321 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 153 166 3.8E-46 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 LH59_20310 acbd2a8d538de48102ba16f9505d0792 321 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 88 99 3.8E-46 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 LH59_20310 acbd2a8d538de48102ba16f9505d0792 321 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 134 150 3.8E-46 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 LH59_20310 acbd2a8d538de48102ba16f9505d0792 321 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 197 206 3.8E-46 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 LH59_20310 acbd2a8d538de48102ba16f9505d0792 321 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 5 316 50.035 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 LH59_20310 acbd2a8d538de48102ba16f9505d0792 321 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 2 318 1.9E-148 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 LH59_20310 acbd2a8d538de48102ba16f9505d0792 321 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 6 148 2.2E-66 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 LH59_20310 acbd2a8d538de48102ba16f9505d0792 321 SUPERFAMILY SSF52096 5 316 1.3E-102 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily LH59_20310 acbd2a8d538de48102ba16f9505d0792 321 Gene3D G3DSA:3.90.226.10 1 318 3.9E-123 T 14-10-2018 LH59_21925 2150c7c14409cb03ef0b2069e6468ed7 632 SUPERFAMILY SSF140990 408 606 3.66E-75 T 14-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 LH59_21925 2150c7c14409cb03ef0b2069e6468ed7 632 Gene3D G3DSA:1.10.8.60 329 405 5.7E-30 T 14-10-2018 LH59_21925 2150c7c14409cb03ef0b2069e6468ed7 632 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 106 597 4.5E-240 T 14-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 LH59_21925 2150c7c14409cb03ef0b2069e6468ed7 632 Gene3D G3DSA:3.40.50.300 143 328 7.1E-70 T 14-10-2018 LH59_21925 2150c7c14409cb03ef0b2069e6468ed7 632 SMART SM00382 190 329 1.5E-25 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_21925 2150c7c14409cb03ef0b2069e6468ed7 632 Pfam PF06480 FtsH Extracellular 10 79 4.4E-6 T 14-10-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 LH59_21925 2150c7c14409cb03ef0b2069e6468ed7 632 ProSitePatterns PS00674 AAA-protein family signature. 297 315 - T 14-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 LH59_21925 2150c7c14409cb03ef0b2069e6468ed7 632 Pfam PF01434 Peptidase family M41 388 596 1.3E-79 T 14-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 LH59_21925 2150c7c14409cb03ef0b2069e6468ed7 632 SUPERFAMILY SSF52540 150 397 8.45E-73 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_21925 2150c7c14409cb03ef0b2069e6468ed7 632 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 3 603 37.422 T 14-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 LH59_21925 2150c7c14409cb03ef0b2069e6468ed7 632 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 194 326 1.9E-45 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 LH59_21925 2150c7c14409cb03ef0b2069e6468ed7 632 Gene3D G3DSA:1.20.58.760 408 605 1.1E-72 T 14-10-2018 LH59_14115 ef7299cf15b84951a1355ec71bbe7fe7 374 Gene3D G3DSA:3.40.50.1980 65 204 2.6E-35 T 14-10-2018 LH59_14115 ef7299cf15b84951a1355ec71bbe7fe7 374 Pfam PF01497 Periplasmic binding protein 88 331 4.2E-16 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain LH59_14115 ef7299cf15b84951a1355ec71bbe7fe7 374 Gene3D G3DSA:3.40.50.1980 207 368 5.7E-40 T 14-10-2018 LH59_14115 ef7299cf15b84951a1355ec71bbe7fe7 374 SUPERFAMILY SSF53807 82 360 1.3E-42 T 14-10-2018 LH59_21535 6cef35ced455924866b4618c0a1c8acd 260 Gene3D G3DSA:3.90.850.10 10 258 1.2E-54 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 LH59_21535 6cef35ced455924866b4618c0a1c8acd 260 SUPERFAMILY SSF56529 12 258 2.44E-40 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 LH59_21535 6cef35ced455924866b4618c0a1c8acd 260 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 65 234 4.3E-8 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 LH59_10575 15178bbeff287f8f43403c105558bcf3 665 SMART SM00267 226 395 3.5E-63 T 14-10-2018 IPR000160 GGDEF domain LH59_10575 15178bbeff287f8f43403c105558bcf3 665 SMART SM00052 405 650 2.5E-106 T 14-10-2018 IPR001633 EAL domain LH59_10575 15178bbeff287f8f43403c105558bcf3 665 SUPERFAMILY SSF55073 242 397 6.91E-45 T 14-10-2018 IPR029787 Nucleotide cyclase LH59_10575 15178bbeff287f8f43403c105558bcf3 665 Pfam PF13426 PAS domain 123 225 7.0E-9 T 14-10-2018 IPR000014 PAS domain LH59_10575 15178bbeff287f8f43403c105558bcf3 665 Gene3D G3DSA:3.20.20.450 408 663 3.4E-92 T 14-10-2018 IPR035919 EAL domain superfamily LH59_10575 15178bbeff287f8f43403c105558bcf3 665 Gene3D G3DSA:3.30.70.270 234 407 7.3E-57 T 14-10-2018 LH59_10575 15178bbeff287f8f43403c105558bcf3 665 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 116 233 9.9E-11 T 14-10-2018 IPR000014 PAS domain LH59_10575 15178bbeff287f8f43403c105558bcf3 665 Gene3D G3DSA:3.30.450.20 103 233 5.7E-15 T 14-10-2018 LH59_10575 15178bbeff287f8f43403c105558bcf3 665 Pfam PF00990 Diguanylate cyclase, GGDEF domain 237 390 3.0E-46 T 14-10-2018 IPR000160 GGDEF domain LH59_10575 15178bbeff287f8f43403c105558bcf3 665 SMART SM00091 111 177 0.0028 T 14-10-2018 IPR000014 PAS domain LH59_10575 15178bbeff287f8f43403c105558bcf3 665 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 234 394 1.2E-33 T 14-10-2018 IPR000160 GGDEF domain LH59_10575 15178bbeff287f8f43403c105558bcf3 665 SUPERFAMILY SSF55785 124 234 1.77E-14 T 14-10-2018 IPR035965 PAS domain superfamily LH59_10575 15178bbeff287f8f43403c105558bcf3 665 Pfam PF00563 EAL domain 412 645 2.1E-68 T 14-10-2018 IPR001633 EAL domain LH59_10575 15178bbeff287f8f43403c105558bcf3 665 SUPERFAMILY SSF141868 412 660 3.14E-85 T 14-10-2018 IPR035919 EAL domain superfamily LH59_03445 fb131d61d5face22597dd50315561851 387 Pfam PF11340 Protein of unknown function (DUF3142) 69 293 2.5E-84 T 14-10-2018 IPR021488 Protein of unknown function DUF3142 LH59_27625 cec87d8598b806de0f92ebd9d18b8cb2 173 Pfam PF00436 Single-strand binding protein family 4 109 6.9E-43 T 14-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 LH59_27625 cec87d8598b806de0f92ebd9d18b8cb2 173 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 2 173 1.3E-55 T 14-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 LH59_27625 cec87d8598b806de0f92ebd9d18b8cb2 173 Gene3D G3DSA:2.40.50.140 1 118 2.3E-47 T 14-10-2018 LH59_27625 cec87d8598b806de0f92ebd9d18b8cb2 173 SUPERFAMILY SSF50249 3 173 2.43E-62 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_27625 cec87d8598b806de0f92ebd9d18b8cb2 173 Hamap MF_00984 Single-stranded DNA-binding protein. 4 113 38.118 T 14-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 LH59_03120 86d35092483683c181b89b38dd44d4de 299 SUPERFAMILY SSF74653 179 289 1.7E-18 T 14-10-2018 LH59_03120 86d35092483683c181b89b38dd44d4de 299 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 213 289 1.1E-12 T 14-10-2018 IPR037682 TonB, C-terminal GO:0055085 LH59_03120 86d35092483683c181b89b38dd44d4de 299 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 214 289 1.4E-13 T 14-10-2018 IPR006260 TonB/TolA, C-terminal LH59_03120 86d35092483683c181b89b38dd44d4de 299 Gene3D G3DSA:3.30.1150.10 131 290 1.0E-19 T 14-10-2018 LH59_25795 82b6c6dde102e42ef383fc99c312edb4 186 Gene3D G3DSA:1.10.40.40 14 65 1.4E-65 T 14-10-2018 LH59_25795 82b6c6dde102e42ef383fc99c312edb4 186 SUPERFAMILY SSF56784 2 177 1.71E-39 T 14-10-2018 IPR036412 HAD-like superfamily LH59_25795 82b6c6dde102e42ef383fc99c312edb4 186 Gene3D G3DSA:3.40.50.1000 3 173 1.4E-65 T 14-10-2018 IPR023214 HAD superfamily LH59_25795 82b6c6dde102e42ef383fc99c312edb4 186 Pfam PF06941 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) 1 175 1.2E-23 T 14-10-2018 IPR010708 5'(3')-deoxyribonucleotidase GO:0008253|GO:0009264 Reactome: R-HSA-73621 LH59_05475 0810907bb2fa84a03122c4e398b794b4 211 Hamap MF_00240 Outer-membrane lipoprotein carrier protein [lolA]. 14 211 27.723 T 14-10-2018 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 LH59_05475 0810907bb2fa84a03122c4e398b794b4 211 Gene3D G3DSA:2.50.20.10 28 210 3.5E-48 T 14-10-2018 LH59_05475 0810907bb2fa84a03122c4e398b794b4 211 SUPERFAMILY SSF89392 30 210 2.16E-42 T 14-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX LH59_05475 0810907bb2fa84a03122c4e398b794b4 211 TIGRFAM TIGR00547 lolA: outer membrane lipoprotein carrier protein LolA 19 208 9.7E-14 T 14-10-2018 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 LH59_05475 0810907bb2fa84a03122c4e398b794b4 211 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 39 200 1.1E-42 T 14-10-2018 IPR004564 Outer membrane lipoprotein carrier protein LolA-like LH59_01550 22b659f677b00189c7d64d4fb68a3a26 238 Pfam PF07729 FCD domain 100 221 1.6E-24 T 14-10-2018 IPR011711 GntR, C-terminal LH59_01550 22b659f677b00189c7d64d4fb68a3a26 238 SMART SM00895 100 222 2.1E-20 T 14-10-2018 IPR011711 GntR, C-terminal LH59_01550 22b659f677b00189c7d64d4fb68a3a26 238 SMART SM00345 32 90 6.1E-20 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_01550 22b659f677b00189c7d64d4fb68a3a26 238 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 64 6.2E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_01550 22b659f677b00189c7d64d4fb68a3a26 238 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 64 80 6.2E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_01550 22b659f677b00189c7d64d4fb68a3a26 238 Pfam PF00392 Bacterial regulatory proteins, gntR family 32 90 4.8E-21 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_01550 22b659f677b00189c7d64d4fb68a3a26 238 SUPERFAMILY SSF48008 99 228 5.23E-25 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_01550 22b659f677b00189c7d64d4fb68a3a26 238 SUPERFAMILY SSF46785 27 94 9.26E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_01550 22b659f677b00189c7d64d4fb68a3a26 238 Gene3D G3DSA:1.10.10.10 13 91 2.3E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_01550 22b659f677b00189c7d64d4fb68a3a26 238 Gene3D G3DSA:1.20.120.530 93 231 3.0E-28 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_25455 18d06877f25313650416767d6137dcdd 339 Pfam PF16220 Domain of unknown function (DUF4880) 15 57 4.9E-8 T 14-10-2018 IPR032623 FecR, N-terminal LH59_25455 18d06877f25313650416767d6137dcdd 339 Gene3D G3DSA:2.60.120.1440 117 259 1.8E-14 T 14-10-2018 LH59_25455 18d06877f25313650416767d6137dcdd 339 Pfam PF04773 FecR protein 127 210 4.6E-14 T 14-10-2018 IPR006860 FecR protein LH59_25455 18d06877f25313650416767d6137dcdd 339 PIRSF PIRSF018266 5 337 6.9E-65 T 14-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component LH59_25155 7fa4337b99b65d1a5698025ab242f6f4 394 Pfam PF04303 PrpF protein 6 390 8.6E-175 T 14-10-2018 IPR007400 PrpF protein LH59_25155 7fa4337b99b65d1a5698025ab242f6f4 394 TIGRFAM TIGR02334 prpF: probable AcnD-accessory protein PrpF 5 391 1.2E-227 T 14-10-2018 IPR012709 2-methyl-aconitate isomerase PrpF GO:0016853|GO:0019629 LH59_25155 7fa4337b99b65d1a5698025ab242f6f4 394 Gene3D G3DSA:3.10.310.10 181 373 5.2E-149 T 14-10-2018 LH59_25155 7fa4337b99b65d1a5698025ab242f6f4 394 SUPERFAMILY SSF54506 2 182 7.85E-71 T 14-10-2018 LH59_25155 7fa4337b99b65d1a5698025ab242f6f4 394 SUPERFAMILY SSF54506 188 390 3.69E-75 T 14-10-2018 LH59_25155 7fa4337b99b65d1a5698025ab242f6f4 394 Gene3D G3DSA:3.10.310.10 11 387 5.2E-149 T 14-10-2018 LH59_17990 6c3ca3d9bba37c0261349c850f69656e 87 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 86 1.1E-28 T 14-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_17990 6c3ca3d9bba37c0261349c850f69656e 87 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 17.465 T 14-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_17990 6c3ca3d9bba37c0261349c850f69656e 87 Gene3D G3DSA:1.20.58.110 1 87 1.6E-28 T 14-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_17990 6c3ca3d9bba37c0261349c850f69656e 87 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 12 86 4.0E-31 T 14-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_17990 6c3ca3d9bba37c0261349c850f69656e 87 SUPERFAMILY SSF46992 3 86 7.72E-30 T 14-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_17990 6c3ca3d9bba37c0261349c850f69656e 87 Pfam PF01649 Ribosomal protein S20 2 84 9.2E-26 T 14-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_25770 e490f8761daec8d5e901e645e93f9732 354 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 2.0E-16 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_25770 e490f8761daec8d5e901e645e93f9732 354 Gene3D G3DSA:3.40.190.290 91 294 1.1E-64 T 14-10-2018 LH59_25770 e490f8761daec8d5e901e645e93f9732 354 Gene3D G3DSA:1.10.10.10 3 88 5.6E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_25770 e490f8761daec8d5e901e645e93f9732 354 SUPERFAMILY SSF53850 90 297 1.12E-42 T 14-10-2018 LH59_25770 e490f8761daec8d5e901e645e93f9732 354 SUPERFAMILY SSF46785 4 84 1.31E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_25770 e490f8761daec8d5e901e645e93f9732 354 Pfam PF03466 LysR substrate binding domain 90 294 1.1E-39 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_05320 3674a96c97ba24773cf4f6eb135510c2 376 Pfam PF00226 DnaJ domain 5 67 3.9E-28 T 14-10-2018 IPR001623 DnaJ domain LH59_05320 3674a96c97ba24773cf4f6eb135510c2 376 Gene3D G3DSA:2.10.230.10 141 211 7.3E-25 T 14-10-2018 LH59_05320 3674a96c97ba24773cf4f6eb135510c2 376 PRINTS PR00625 DnaJ domain signature 7 25 8.0E-33 T 14-10-2018 IPR001623 DnaJ domain LH59_05320 3674a96c97ba24773cf4f6eb135510c2 376 PRINTS PR00625 DnaJ domain signature 42 62 8.0E-33 T 14-10-2018 IPR001623 DnaJ domain LH59_05320 3674a96c97ba24773cf4f6eb135510c2 376 PRINTS PR00625 DnaJ domain signature 62 81 8.0E-33 T 14-10-2018 IPR001623 DnaJ domain LH59_05320 3674a96c97ba24773cf4f6eb135510c2 376 PRINTS PR00625 DnaJ domain signature 25 40 8.0E-33 T 14-10-2018 IPR001623 DnaJ domain LH59_05320 3674a96c97ba24773cf4f6eb135510c2 376 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 374 41.882 T 14-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 LH59_05320 3674a96c97ba24773cf4f6eb135510c2 376 SMART SM00271 4 62 5.3E-32 T 14-10-2018 IPR001623 DnaJ domain LH59_05320 3674a96c97ba24773cf4f6eb135510c2 376 SUPERFAMILY SSF49493 261 346 6.15E-24 T 14-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 LH59_05320 3674a96c97ba24773cf4f6eb135510c2 376 Pfam PF01556 DnaJ C terminal domain 123 335 3.3E-41 T 14-10-2018 IPR002939 Chaperone DnaJ, C-terminal LH59_05320 3674a96c97ba24773cf4f6eb135510c2 376 ProSitePatterns PS00636 Nt-dnaJ domain signature. 47 66 - T 14-10-2018 IPR018253 DnaJ domain, conserved site LH59_05320 3674a96c97ba24773cf4f6eb135510c2 376 Gene3D G3DSA:2.60.260.20 258 363 2.6E-30 T 14-10-2018 LH59_05320 3674a96c97ba24773cf4f6eb135510c2 376 SUPERFAMILY SSF49493 117 263 3.53E-19 T 14-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 LH59_05320 3674a96c97ba24773cf4f6eb135510c2 376 SUPERFAMILY SSF57938 136 212 6.54E-22 T 14-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily LH59_05320 3674a96c97ba24773cf4f6eb135510c2 376 Pfam PF00684 DnaJ central domain 149 209 1.2E-13 T 14-10-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 LH59_05320 3674a96c97ba24773cf4f6eb135510c2 376 SUPERFAMILY SSF46565 1 109 6.02E-38 T 14-10-2018 IPR036869 Chaperone J-domain superfamily LH59_05320 3674a96c97ba24773cf4f6eb135510c2 376 Gene3D G3DSA:1.10.287.110 1 113 2.2E-38 T 14-10-2018 IPR036869 Chaperone J-domain superfamily LH59_05320 3674a96c97ba24773cf4f6eb135510c2 376 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 351 2.4E-137 T 14-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 LH59_10070 664c1fa0ec68c375e16843db73c45303 292 Pfam PF02311 AraC-like ligand binding domain 19 146 7.6E-16 T 14-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 LH59_10070 664c1fa0ec68c375e16843db73c45303 292 SUPERFAMILY SSF51215 26 147 4.97E-17 T 14-10-2018 IPR037923 Transcription regulator HTH-like LH59_10070 664c1fa0ec68c375e16843db73c45303 292 SUPERFAMILY SSF46689 237 285 1.03E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_10070 664c1fa0ec68c375e16843db73c45303 292 Gene3D G3DSA:1.10.10.60 180 243 2.0E-9 T 14-10-2018 LH59_10070 664c1fa0ec68c375e16843db73c45303 292 Pfam PF12833 Helix-turn-helix domain 207 284 9.3E-20 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_10070 664c1fa0ec68c375e16843db73c45303 292 Gene3D G3DSA:1.10.10.60 244 292 2.8E-11 T 14-10-2018 LH59_10070 664c1fa0ec68c375e16843db73c45303 292 Gene3D G3DSA:2.60.120.10 24 84 1.6E-6 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_10070 664c1fa0ec68c375e16843db73c45303 292 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 238 279 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 LH59_10070 664c1fa0ec68c375e16843db73c45303 292 SMART SM00342 201 283 4.9E-22 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_14125 f2ec68bceb81d9f2ab122c07fffbcfb5 338 Pfam PF01032 FecCD transport family 28 330 9.9E-68 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 LH59_14125 f2ec68bceb81d9f2ab122c07fffbcfb5 338 SUPERFAMILY SSF81345 10 329 5.62E-57 T 14-10-2018 IPR037294 ABC transporter, BtuC-like LH59_14125 f2ec68bceb81d9f2ab122c07fffbcfb5 338 Gene3D G3DSA:1.10.3470.10 14 336 1.7E-70 T 14-10-2018 IPR037294 ABC transporter, BtuC-like LH59_04780 1459394ac6af64ad4144f737d2aa7c34 1919 Gene3D G3DSA:3.40.50.300 1040 1162 8.5E-27 T 14-10-2018 LH59_04780 1459394ac6af64ad4144f737d2aa7c34 1919 SUPERFAMILY SSF52540 1577 1888 5.49E-39 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_04780 1459394ac6af64ad4144f737d2aa7c34 1919 SUPERFAMILY SSF52540 1055 1531 3.45E-39 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_04780 1459394ac6af64ad4144f737d2aa7c34 1919 SUPERFAMILY SSF52540 664 966 2.12E-38 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_04780 1459394ac6af64ad4144f737d2aa7c34 1919 Pfam PF00005 ABC transporter 666 894 2.6E-6 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_04780 1459394ac6af64ad4144f737d2aa7c34 1919 Gene3D G3DSA:3.30.190.20 1175 1296 1.2E-27 T 14-10-2018 LH59_04780 1459394ac6af64ad4144f737d2aa7c34 1919 Gene3D G3DSA:1.20.1580.10 1655 1792 7.5E-131 T 14-10-2018 LH59_04780 1459394ac6af64ad4144f737d2aa7c34 1919 SUPERFAMILY SSF52540 6 613 2.47E-37 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_04780 1459394ac6af64ad4144f737d2aa7c34 1919 Gene3D G3DSA:1.20.1580.10 734 876 1.5E-128 T 14-10-2018 LH59_04780 1459394ac6af64ad4144f737d2aa7c34 1919 Gene3D G3DSA:3.40.50.300 1314 1559 1.5E-57 T 14-10-2018 LH59_04780 1459394ac6af64ad4144f737d2aa7c34 1919 Gene3D G3DSA:3.40.50.300 1575 1912 7.5E-131 T 14-10-2018 LH59_04780 1459394ac6af64ad4144f737d2aa7c34 1919 ProSitePatterns PS00211 ABC transporters family signature. 1449 1463 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_04780 1459394ac6af64ad4144f737d2aa7c34 1919 ProSitePatterns PS00211 ABC transporters family signature. 1792 1806 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_04780 1459394ac6af64ad4144f737d2aa7c34 1919 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 5 980 2.9E-288 T 14-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 LH59_04780 1459394ac6af64ad4144f737d2aa7c34 1919 SMART SM00382 1072 1526 3.1 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_04780 1459394ac6af64ad4144f737d2aa7c34 1919 SMART SM00382 675 962 0.62 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_04780 1459394ac6af64ad4144f737d2aa7c34 1919 SMART SM00382 1594 1881 2.9 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_04780 1459394ac6af64ad4144f737d2aa7c34 1919 Gene3D G3DSA:3.40.50.300 659 992 1.5E-128 T 14-10-2018 LH59_12815 fc4860ca2f51e7136bbeea8d31ae830f 696 Pfam PF00270 DEAD/DEAH box helicase 293 435 2.9E-16 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 LH59_12815 fc4860ca2f51e7136bbeea8d31ae830f 696 Gene3D G3DSA:3.40.50.300 462 633 1.5E-55 T 14-10-2018 LH59_12815 fc4860ca2f51e7136bbeea8d31ae830f 696 Gene3D G3DSA:2.40.50.140 52 142 7.0E-7 T 14-10-2018 LH59_12815 fc4860ca2f51e7136bbeea8d31ae830f 696 SUPERFAMILY SSF52540 213 457 1.14E-53 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_12815 fc4860ca2f51e7136bbeea8d31ae830f 696 SMART SM00490 509 592 1.7E-21 T 14-10-2018 IPR001650 Helicase, C-terminal LH59_12815 fc4860ca2f51e7136bbeea8d31ae830f 696 SMART SM00487 267 463 2.0E-28 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain LH59_12815 fc4860ca2f51e7136bbeea8d31ae830f 696 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 38 668 2.6E-214 T 14-10-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 LH59_12815 fc4860ca2f51e7136bbeea8d31ae830f 696 SUPERFAMILY SSF52540 456 657 8.54E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_12815 fc4860ca2f51e7136bbeea8d31ae830f 696 Pfam PF00271 Helicase conserved C-terminal domain 481 591 3.9E-17 T 14-10-2018 IPR001650 Helicase, C-terminal LH59_12815 fc4860ca2f51e7136bbeea8d31ae830f 696 Gene3D G3DSA:3.40.50.300 214 454 7.7E-82 T 14-10-2018 LH59_12815 fc4860ca2f51e7136bbeea8d31ae830f 696 SUPERFAMILY SSF50249 25 174 7.88E-27 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_12815 fc4860ca2f51e7136bbeea8d31ae830f 696 Pfam PF17191 RecG wedge domain 25 171 7.3E-14 T 14-10-2018 IPR033454 RecG, wedge domain LH59_16475 ffbf33eb759e7c3c755bc971e849b1b8 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 2.4E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_16475 ffbf33eb759e7c3c755bc971e849b1b8 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 2.4E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_16475 ffbf33eb759e7c3c755bc971e849b1b8 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 2.4E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_16475 ffbf33eb759e7c3c755bc971e849b1b8 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.4E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_16475 ffbf33eb759e7c3c755bc971e849b1b8 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 2.4E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_16475 ffbf33eb759e7c3c755bc971e849b1b8 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 2.4E-43 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_16475 ffbf33eb759e7c3c755bc971e849b1b8 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 245 2.4E-55 T 14-10-2018 LH59_16475 ffbf33eb759e7c3c755bc971e849b1b8 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LH59_16475 ffbf33eb759e7c3c755bc971e849b1b8 247 Gene3D G3DSA:3.40.50.720 4 246 2.7E-70 T 14-10-2018 LH59_16475 ffbf33eb759e7c3c755bc971e849b1b8 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 2.8E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_16475 ffbf33eb759e7c3c755bc971e849b1b8 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 2.8E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_16475 ffbf33eb759e7c3c755bc971e849b1b8 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 2.8E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_16475 ffbf33eb759e7c3c755bc971e849b1b8 247 SUPERFAMILY SSF51735 7 246 2.51E-66 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_12605 ac8f8ebeaf8186a2326606cd36927fd2 250 Gene3D G3DSA:3.40.190.10 33 246 2.4E-82 T 14-10-2018 LH59_12605 ac8f8ebeaf8186a2326606cd36927fd2 250 SMART SM00062 30 249 2.0E-70 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_12605 ac8f8ebeaf8186a2326606cd36927fd2 250 SMART SM00079 30 248 7.2E-9 T 14-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 LH59_12605 ac8f8ebeaf8186a2326606cd36927fd2 250 Gene3D G3DSA:3.40.190.10 114 209 2.4E-82 T 14-10-2018 LH59_12605 ac8f8ebeaf8186a2326606cd36927fd2 250 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 52 65 - T 14-10-2018 IPR018313 Solute-binding protein family 3, conserved site LH59_12605 ac8f8ebeaf8186a2326606cd36927fd2 250 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 31 248 2.7E-70 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_12605 ac8f8ebeaf8186a2326606cd36927fd2 250 SUPERFAMILY SSF53850 4 249 2.59E-76 T 14-10-2018 LH59_12000 81aaeb25c2ddb108aa6ea50958cc9ed0 144 Gene3D G3DSA:2.60.40.1120 73 144 6.5E-6 T 14-10-2018 LH59_00780 ded902d6a9a415f18716b1baffc5ab12 402 Gene3D G3DSA:3.20.20.140 63 355 4.9E-113 T 14-10-2018 LH59_00780 ded902d6a9a415f18716b1baffc5ab12 402 SUPERFAMILY SSF51338 6 73 8.1E-12 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 LH59_00780 ded902d6a9a415f18716b1baffc5ab12 402 Pfam PF01979 Amidohydrolase family 57 395 5.4E-32 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 LH59_00780 ded902d6a9a415f18716b1baffc5ab12 402 SUPERFAMILY SSF51556 61 354 1.54E-85 T 14-10-2018 IPR032466 Metal-dependent hydrolase LH59_00780 ded902d6a9a415f18716b1baffc5ab12 402 Gene3D G3DSA:2.30.40.10 14 395 4.9E-113 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 LH59_12470 9b7704d853e16ccd2d4811f11782a7d1 302 Gene3D G3DSA:1.10.10.10 8 96 4.2E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_12470 9b7704d853e16ccd2d4811f11782a7d1 302 Pfam PF03466 LysR substrate binding domain 92 294 6.5E-33 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_12470 9b7704d853e16ccd2d4811f11782a7d1 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 63 7.0E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_12470 9b7704d853e16ccd2d4811f11782a7d1 302 SUPERFAMILY SSF46785 6 87 2.06E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_12470 9b7704d853e16ccd2d4811f11782a7d1 302 Gene3D G3DSA:3.40.190.10 166 265 5.7E-43 T 14-10-2018 LH59_12470 9b7704d853e16ccd2d4811f11782a7d1 302 Gene3D G3DSA:3.40.190.10 104 291 5.7E-43 T 14-10-2018 LH59_12470 9b7704d853e16ccd2d4811f11782a7d1 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 1.3E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_12470 9b7704d853e16ccd2d4811f11782a7d1 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 1.3E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_12470 9b7704d853e16ccd2d4811f11782a7d1 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 1.3E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_12470 9b7704d853e16ccd2d4811f11782a7d1 302 SUPERFAMILY SSF53850 93 298 6.11E-34 T 14-10-2018 LH59_25115 ab5198a350b6ac1b7792d58e5fabd9e6 420 SUPERFAMILY SSF55031 216 334 7.5E-22 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain LH59_25115 ab5198a350b6ac1b7792d58e5fabd9e6 420 Gene3D G3DSA:3.40.630.10 27 409 7.1E-131 T 14-10-2018 LH59_25115 ab5198a350b6ac1b7792d58e5fabd9e6 420 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 11 414 1.0E-113 T 14-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 LH59_25115 ab5198a350b6ac1b7792d58e5fabd9e6 420 SUPERFAMILY SSF53187 4 415 3.83E-86 T 14-10-2018 LH59_25115 ab5198a350b6ac1b7792d58e5fabd9e6 420 Gene3D G3DSA:3.30.70.360 216 333 7.1E-131 T 14-10-2018 LH59_25115 ab5198a350b6ac1b7792d58e5fabd9e6 420 Pfam PF01546 Peptidase family M20/M25/M40 81 412 1.1E-28 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 LH59_25115 ab5198a350b6ac1b7792d58e5fabd9e6 420 PIRSF PIRSF001235 8 419 4.8E-136 T 14-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 LH59_14110 b6283af26f85a900970f2a7b1c04d233 734 Gene3D G3DSA:2.170.130.10 60 192 2.8E-38 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily LH59_14110 b6283af26f85a900970f2a7b1c04d233 734 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 85 733 8.2E-101 T 14-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 LH59_14110 b6283af26f85a900970f2a7b1c04d233 734 Pfam PF07715 TonB-dependent Receptor Plug Domain 83 183 1.2E-15 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_14110 b6283af26f85a900970f2a7b1c04d233 734 Gene3D G3DSA:2.40.170.20 193 734 8.6E-203 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_14110 b6283af26f85a900970f2a7b1c04d233 734 Pfam PF00593 TonB dependent receptor 268 732 4.7E-52 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_14110 b6283af26f85a900970f2a7b1c04d233 734 SUPERFAMILY SSF56935 40 733 7.02E-125 T 14-10-2018 LH59_01070 2acacf6a06e910f7698bd0a255e2fa25 329 Gene3D G3DSA:2.40.100.10 183 328 1.2E-41 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily LH59_01070 2acacf6a06e910f7698bd0a255e2fa25 329 SUPERFAMILY SSF50891 186 309 1.02E-8 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily LH59_01070 2acacf6a06e910f7698bd0a255e2fa25 329 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 30 303 2.9E-85 T 14-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B LH59_01070 2acacf6a06e910f7698bd0a255e2fa25 329 SMART SM00797 29 321 4.2E-140 T 14-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B LH59_01070 2acacf6a06e910f7698bd0a255e2fa25 329 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 8 327 1.6E-83 T 14-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B LH59_01895 f06058611de7a218819e3dc127dc669f 398 SUPERFAMILY SSF53822 39 395 2.25E-101 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_01895 f06058611de7a218819e3dc127dc669f 398 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 61 77 9.7E-7 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 LH59_01895 f06058611de7a218819e3dc127dc669f 398 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 290 303 9.7E-7 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 LH59_01895 f06058611de7a218819e3dc127dc669f 398 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 39 55 9.7E-7 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 LH59_01895 f06058611de7a218819e3dc127dc669f 398 Gene3D G3DSA:3.40.50.2300 42 367 1.9E-142 T 14-10-2018 LH59_01895 f06058611de7a218819e3dc127dc669f 398 Pfam PF13433 Periplasmic binding protein domain 39 397 1.9E-139 T 14-10-2018 LH59_01895 f06058611de7a218819e3dc127dc669f 398 Gene3D G3DSA:3.40.50.2300 154 386 1.9E-142 T 14-10-2018 LH59_01895 f06058611de7a218819e3dc127dc669f 398 TIGRFAM TIGR03407 urea_ABC_UrtA: urea ABC transporter, urea binding protein 39 395 1.5E-156 T 14-10-2018 IPR017777 Urea ABC transporter, substrate-binding protein UrtA-like LH59_00505 f5671509c9717c821c10e7a9ec0ed413 408 Gene3D G3DSA:1.20.140.10 248 391 7.4E-39 T 14-10-2018 LH59_00505 f5671509c9717c821c10e7a9ec0ed413 408 SUPERFAMILY SSF56645 1 250 1.7E-59 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 LH59_00505 f5671509c9717c821c10e7a9ec0ed413 408 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 130 226 6.9E-19 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 LH59_00505 f5671509c9717c821c10e7a9ec0ed413 408 SUPERFAMILY SSF47203 237 390 1.77E-47 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 LH59_00505 f5671509c9717c821c10e7a9ec0ed413 408 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 239 387 2.1E-37 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LH59_00505 f5671509c9717c821c10e7a9ec0ed413 408 Gene3D G3DSA:1.10.540.10 1 128 8.9E-39 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 LH59_00505 f5671509c9717c821c10e7a9ec0ed413 408 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 125 1.8E-17 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 LH59_00505 f5671509c9717c821c10e7a9ec0ed413 408 PIRSF PIRSF016578 142 203 1.1 T 14-10-2018 LH59_00505 f5671509c9717c821c10e7a9ec0ed413 408 PIRSF PIRSF016578 10 88 6.7 T 14-10-2018 LH59_00505 f5671509c9717c821c10e7a9ec0ed413 408 PIRSF PIRSF016578 249 393 1.1E-11 T 14-10-2018 LH59_00505 f5671509c9717c821c10e7a9ec0ed413 408 Gene3D G3DSA:2.40.110.10 129 247 6.7E-33 T 14-10-2018 LH59_16230 9cf1cf0bd7f9ce1e74cc8b9b7c8cbc21 340 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 245 329 2.9E-26 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_16230 9cf1cf0bd7f9ce1e74cc8b9b7c8cbc21 340 ProSitePatterns PS00211 ABC transporters family signature. 168 182 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_16230 9cf1cf0bd7f9ce1e74cc8b9b7c8cbc21 340 SMART SM00382 46 253 8.0E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_16230 9cf1cf0bd7f9ce1e74cc8b9b7c8cbc21 340 Pfam PF00005 ABC transporter 38 195 2.8E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_16230 9cf1cf0bd7f9ce1e74cc8b9b7c8cbc21 340 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 247 311 7.9E-20 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_16230 9cf1cf0bd7f9ce1e74cc8b9b7c8cbc21 340 SUPERFAMILY SSF52540 18 266 1.15E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_16230 9cf1cf0bd7f9ce1e74cc8b9b7c8cbc21 340 Gene3D G3DSA:3.40.50.300 16 337 6.6E-98 T 14-10-2018 LH59_22585 0a684314fbe9ba83057e3b39c59161b9 391 Gene3D G3DSA:3.40.50.1260 10 386 3.5E-145 T 14-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_22585 0a684314fbe9ba83057e3b39c59161b9 391 PIRSF PIRSF000724 4 391 5.9E-134 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_22585 0a684314fbe9ba83057e3b39c59161b9 391 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 14 24 - T 14-10-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_22585 0a684314fbe9ba83057e3b39c59161b9 391 Pfam PF00162 Phosphoglycerate kinase 10 378 3.3E-138 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_22585 0a684314fbe9ba83057e3b39c59161b9 391 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 2.0E-80 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_22585 0a684314fbe9ba83057e3b39c59161b9 391 PRINTS PR00477 Phosphoglycerate kinase family signature 104 119 2.0E-80 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_22585 0a684314fbe9ba83057e3b39c59161b9 391 PRINTS PR00477 Phosphoglycerate kinase family signature 308 333 2.0E-80 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_22585 0a684314fbe9ba83057e3b39c59161b9 391 PRINTS PR00477 Phosphoglycerate kinase family signature 364 381 2.0E-80 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_22585 0a684314fbe9ba83057e3b39c59161b9 391 PRINTS PR00477 Phosphoglycerate kinase family signature 9 25 2.0E-80 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_22585 0a684314fbe9ba83057e3b39c59161b9 391 PRINTS PR00477 Phosphoglycerate kinase family signature 186 205 2.0E-80 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_22585 0a684314fbe9ba83057e3b39c59161b9 391 PRINTS PR00477 Phosphoglycerate kinase family signature 132 154 2.0E-80 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_22585 0a684314fbe9ba83057e3b39c59161b9 391 PRINTS PR00477 Phosphoglycerate kinase family signature 341 352 2.0E-80 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_22585 0a684314fbe9ba83057e3b39c59161b9 391 PRINTS PR00477 Phosphoglycerate kinase family signature 163 185 2.0E-80 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_22585 0a684314fbe9ba83057e3b39c59161b9 391 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 3 388 39.421 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_22585 0a684314fbe9ba83057e3b39c59161b9 391 Gene3D G3DSA:3.40.50.1260 165 378 3.5E-145 T 14-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_22585 0a684314fbe9ba83057e3b39c59161b9 391 SUPERFAMILY SSF53748 10 388 1.12E-140 T 14-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_20895 5eb2a0c054e815a1f6b0f2cd0307cacd 245 SUPERFAMILY SSF46894 136 236 2.61E-23 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LH59_20895 5eb2a0c054e815a1f6b0f2cd0307cacd 245 SUPERFAMILY SSF52172 4 134 4.27E-40 T 14-10-2018 IPR011006 CheY-like superfamily LH59_20895 5eb2a0c054e815a1f6b0f2cd0307cacd 245 Gene3D G3DSA:3.40.50.2300 1 129 2.8E-37 T 14-10-2018 LH59_20895 5eb2a0c054e815a1f6b0f2cd0307cacd 245 Pfam PF00072 Response regulator receiver domain 7 118 8.4E-30 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_20895 5eb2a0c054e815a1f6b0f2cd0307cacd 245 SMART SM00862 159 235 1.2E-18 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_20895 5eb2a0c054e815a1f6b0f2cd0307cacd 245 SMART SM00448 5 117 6.5E-39 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_20895 5eb2a0c054e815a1f6b0f2cd0307cacd 245 Gene3D G3DSA:1.10.10.10 130 240 1.1E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_20895 5eb2a0c054e815a1f6b0f2cd0307cacd 245 Pfam PF00486 Transcriptional regulatory protein, C terminal 162 235 9.0E-19 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_26250 4ee848641baf1c75f7ceaa5cb3d66891 287 Gene3D G3DSA:1.10.10.10 2 87 9.9E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_26250 4ee848641baf1c75f7ceaa5cb3d66891 287 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 1.1E-13 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_26250 4ee848641baf1c75f7ceaa5cb3d66891 287 SUPERFAMILY SSF53850 90 283 1.68E-31 T 14-10-2018 LH59_26250 4ee848641baf1c75f7ceaa5cb3d66891 287 Pfam PF03466 LysR substrate binding domain 89 277 2.5E-26 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_26250 4ee848641baf1c75f7ceaa5cb3d66891 287 SUPERFAMILY SSF46785 1 111 7.94E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_26250 4ee848641baf1c75f7ceaa5cb3d66891 287 Gene3D G3DSA:3.40.190.290 91 279 8.3E-25 T 14-10-2018 LH59_27520 9604cdc12563acadbf08de93f2c7f168 643 Gene3D G3DSA:3.40.47.10 229 376 8.7E-28 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_27520 9604cdc12563acadbf08de93f2c7f168 643 Pfam PF14518 Iron-containing redox enzyme 512 630 4.7E-10 T 14-10-2018 LH59_27520 9604cdc12563acadbf08de93f2c7f168 643 SUPERFAMILY SSF53901 253 370 2.11E-16 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_27520 9604cdc12563acadbf08de93f2c7f168 643 Gene3D G3DSA:3.40.47.10 8 200 6.6E-35 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_27520 9604cdc12563acadbf08de93f2c7f168 643 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 285 357 5.8E-9 T 14-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 LH59_27520 9604cdc12563acadbf08de93f2c7f168 643 SUPERFAMILY SSF48613 423 637 2.67E-27 T 14-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 LH59_27520 9604cdc12563acadbf08de93f2c7f168 643 Gene3D G3DSA:1.20.910.10 421 643 3.3E-44 T 14-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 LH59_27520 9604cdc12563acadbf08de93f2c7f168 643 SUPERFAMILY SSF53901 6 201 3.33E-28 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_27520 9604cdc12563acadbf08de93f2c7f168 643 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 128 198 2.2E-4 T 14-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 LH59_08830 aaa885dc6db35c470d26e0d53d8ecfd9 458 SUPERFAMILY SSF52172 14 198 7.83E-40 T 14-10-2018 IPR011006 CheY-like superfamily LH59_08830 aaa885dc6db35c470d26e0d53d8ecfd9 458 Gene3D G3DSA:1.10.8.60 324 387 8.5E-19 T 14-10-2018 LH59_08830 aaa885dc6db35c470d26e0d53d8ecfd9 458 SUPERFAMILY SSF46689 364 449 9.32E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_08830 aaa885dc6db35c470d26e0d53d8ecfd9 458 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 366 375 - T 14-10-2018 IPR025944 Sigma-54 interaction domain, conserved site LH59_08830 aaa885dc6db35c470d26e0d53d8ecfd9 458 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 177 190 - T 14-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 LH59_08830 aaa885dc6db35c470d26e0d53d8ecfd9 458 Gene3D G3DSA:3.40.50.2300 8 137 3.2E-34 T 14-10-2018 LH59_08830 aaa885dc6db35c470d26e0d53d8ecfd9 458 Pfam PF02954 Bacterial regulatory protein, Fis family 406 446 3.7E-7 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 LH59_08830 aaa885dc6db35c470d26e0d53d8ecfd9 458 SMART SM00448 12 123 1.9E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_08830 aaa885dc6db35c470d26e0d53d8ecfd9 458 Pfam PF00072 Response regulator receiver domain 15 123 2.1E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_08830 aaa885dc6db35c470d26e0d53d8ecfd9 458 Gene3D G3DSA:1.10.10.60 388 453 1.9E-12 T 14-10-2018 LH59_08830 aaa885dc6db35c470d26e0d53d8ecfd9 458 SUPERFAMILY SSF52540 153 382 1.14E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_08830 aaa885dc6db35c470d26e0d53d8ecfd9 458 Pfam PF00158 Sigma-54 interaction domain 154 319 1.1E-65 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 LH59_08830 aaa885dc6db35c470d26e0d53d8ecfd9 458 Gene3D G3DSA:3.40.50.300 141 323 2.5E-58 T 14-10-2018 LH59_08830 aaa885dc6db35c470d26e0d53d8ecfd9 458 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 239 254 - T 14-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 LH59_08830 aaa885dc6db35c470d26e0d53d8ecfd9 458 SMART SM00382 173 316 4.0E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_11780 a11343c8e9be743356a13a3ace7cd755 384 SUPERFAMILY SSF56645 2 240 9.42E-78 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 LH59_11780 a11343c8e9be743356a13a3ace7cd755 384 Gene3D G3DSA:1.20.140.10 232 382 1.1E-52 T 14-10-2018 LH59_11780 a11343c8e9be743356a13a3ace7cd755 384 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 215 5.9E-26 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 LH59_11780 a11343c8e9be743356a13a3ace7cd755 384 PIRSF PIRSF016578 3 193 2.8E-7 T 14-10-2018 LH59_11780 a11343c8e9be743356a13a3ace7cd755 384 PIRSF PIRSF016578 211 382 9.2E-12 T 14-10-2018 LH59_11780 a11343c8e9be743356a13a3ace7cd755 384 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 123 135 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 LH59_11780 a11343c8e9be743356a13a3ace7cd755 384 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 227 377 2.8E-45 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LH59_11780 a11343c8e9be743356a13a3ace7cd755 384 Gene3D G3DSA:2.40.110.10 120 231 7.3E-44 T 14-10-2018 LH59_11780 a11343c8e9be743356a13a3ace7cd755 384 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 116 1.2E-26 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 LH59_11780 a11343c8e9be743356a13a3ace7cd755 384 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 335 354 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 LH59_11780 a11343c8e9be743356a13a3ace7cd755 384 SUPERFAMILY SSF47203 225 378 4.99E-57 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 LH59_11780 a11343c8e9be743356a13a3ace7cd755 384 Gene3D G3DSA:1.10.540.10 1 119 2.5E-32 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 LH59_03290 5b06e31194a9dd5b549f65bf9589d17e 468 PRINTS PR00987 Glutamyl-tRNA synthetase signature 12 24 5.6E-27 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 LH59_03290 5b06e31194a9dd5b549f65bf9589d17e 468 PRINTS PR00987 Glutamyl-tRNA synthetase signature 26 37 5.6E-27 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 LH59_03290 5b06e31194a9dd5b549f65bf9589d17e 468 PRINTS PR00987 Glutamyl-tRNA synthetase signature 189 199 5.6E-27 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 LH59_03290 5b06e31194a9dd5b549f65bf9589d17e 468 PRINTS PR00987 Glutamyl-tRNA synthetase signature 41 54 5.6E-27 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 LH59_03290 5b06e31194a9dd5b549f65bf9589d17e 468 PRINTS PR00987 Glutamyl-tRNA synthetase signature 205 213 5.6E-27 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 LH59_03290 5b06e31194a9dd5b549f65bf9589d17e 468 SUPERFAMILY SSF48163 309 466 3.53E-37 T 14-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 LH59_03290 5b06e31194a9dd5b549f65bf9589d17e 468 SUPERFAMILY SSF52374 9 305 6.44E-112 T 14-10-2018 LH59_03290 5b06e31194a9dd5b549f65bf9589d17e 468 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 9 315 9.4E-105 T 14-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 LH59_03290 5b06e31194a9dd5b549f65bf9589d17e 468 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 9 466 1.2E-165 T 14-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 LH59_03290 5b06e31194a9dd5b549f65bf9589d17e 468 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 15 26 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 LH59_03290 5b06e31194a9dd5b549f65bf9589d17e 468 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 8 468 30.914 T 14-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 LH59_03290 5b06e31194a9dd5b549f65bf9589d17e 468 Gene3D G3DSA:3.40.50.620 7 324 4.4E-137 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LH59_03290 5b06e31194a9dd5b549f65bf9589d17e 468 Gene3D G3DSA:1.10.8.70 394 468 1.8E-13 T 14-10-2018 IPR020752 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 1 GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 LH59_03290 5b06e31194a9dd5b549f65bf9589d17e 468 Gene3D G3DSA:1.10.8.70 325 393 1.1E-6 T 14-10-2018 IPR020752 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 1 GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 LH59_07425 ad997b2d516a2f34f556ea4e92ca4c1e 432 SUPERFAMILY SSF52540 17 245 9.47E-53 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_07425 ad997b2d516a2f34f556ea4e92ca4c1e 432 Gene3D G3DSA:2.40.30.10 233 323 1.9E-25 T 14-10-2018 LH59_07425 ad997b2d516a2f34f556ea4e92ca4c1e 432 Gene3D G3DSA:2.40.30.10 326 431 9.5E-32 T 14-10-2018 LH59_07425 ad997b2d516a2f34f556ea4e92ca4c1e 432 PRINTS PR00315 GTP-binding elongation factor signature 18 31 1.1E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_07425 ad997b2d516a2f34f556ea4e92ca4c1e 432 PRINTS PR00315 GTP-binding elongation factor signature 155 164 1.1E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_07425 ad997b2d516a2f34f556ea4e92ca4c1e 432 PRINTS PR00315 GTP-binding elongation factor signature 78 86 1.1E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_07425 ad997b2d516a2f34f556ea4e92ca4c1e 432 PRINTS PR00315 GTP-binding elongation factor signature 98 108 1.1E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_07425 ad997b2d516a2f34f556ea4e92ca4c1e 432 PRINTS PR00315 GTP-binding elongation factor signature 114 125 1.1E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_07425 ad997b2d516a2f34f556ea4e92ca4c1e 432 SUPERFAMILY SSF50465 327 431 1.39E-27 T 14-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal LH59_07425 ad997b2d516a2f34f556ea4e92ca4c1e 432 Gene3D G3DSA:3.40.50.300 9 230 8.6E-61 T 14-10-2018 LH59_07425 ad997b2d516a2f34f556ea4e92ca4c1e 432 Pfam PF00009 Elongation factor Tu GTP binding domain 17 209 1.7E-37 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_07425 ad997b2d516a2f34f556ea4e92ca4c1e 432 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 17 431 1.6E-162 T 14-10-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 LH59_07425 ad997b2d516a2f34f556ea4e92ca4c1e 432 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 71 86 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site LH59_07425 ad997b2d516a2f34f556ea4e92ca4c1e 432 SUPERFAMILY SSF50447 234 324 2.06E-22 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily LH59_07425 ad997b2d516a2f34f556ea4e92ca4c1e 432 Pfam PF03144 Elongation factor Tu domain 2 260 319 4.2E-7 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 LH59_00340 941ad53c7ed74098d4241b21c47f2f36 885 Pfam PF14351 Domain of unknown function (DUF4401) 360 689 1.1E-64 T 14-10-2018 IPR025513 Domain of unknown function DUF4401 LH59_00340 941ad53c7ed74098d4241b21c47f2f36 885 Pfam PF14345 GDYXXLXY protein 728 877 3.9E-38 T 14-10-2018 IPR025833 GDYXXLXY protein LH59_00340 941ad53c7ed74098d4241b21c47f2f36 885 Pfam PF09925 Predicted membrane protein (DUF2157) 17 137 2.3E-24 T 14-10-2018 IPR018677 Domain of unknown function DUF2157 LH59_26775 07162eb698d32d2de2a9b7e56e27ca16 485 Pfam PF02934 GatB/GatE catalytic domain 5 293 1.9E-110 T 14-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 LH59_26775 07162eb698d32d2de2a9b7e56e27ca16 485 Gene3D G3DSA:1.10.10.410 423 485 5.5E-26 T 14-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal LH59_26775 07162eb698d32d2de2a9b7e56e27ca16 485 Pfam PF02637 GatB domain 333 483 6.2E-52 T 14-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 LH59_26775 07162eb698d32d2de2a9b7e56e27ca16 485 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 148 162 - T 14-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 LH59_26775 07162eb698d32d2de2a9b7e56e27ca16 485 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 1 483 1.2E-165 T 14-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 LH59_26775 07162eb698d32d2de2a9b7e56e27ca16 485 SMART SM00845 332 483 3.4E-78 T 14-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 LH59_26775 07162eb698d32d2de2a9b7e56e27ca16 485 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 2 484 37.912 T 14-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 LH59_26775 07162eb698d32d2de2a9b7e56e27ca16 485 SUPERFAMILY SSF55931 4 300 1.18E-118 T 14-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 LH59_26775 07162eb698d32d2de2a9b7e56e27ca16 485 SUPERFAMILY SSF89095 301 407 2.88E-31 T 14-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 LH59_26775 07162eb698d32d2de2a9b7e56e27ca16 485 Gene3D G3DSA:1.10.150.380 301 422 4.1E-32 T 14-10-2018 LH59_00555 3dcd97203901316c5f7d5dc9344525ef 671 Pfam PF00364 Biotin-requiring enzyme 604 669 1.2E-18 T 14-10-2018 IPR000089 Biotin/lipoyl attachment LH59_00555 3dcd97203901316c5f7d5dc9344525ef 671 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 626 643 - T 14-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LH59_00555 3dcd97203901316c5f7d5dc9344525ef 671 Pfam PF02785 Biotin carboxylase C-terminal domain 336 448 2.9E-35 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LH59_00555 3dcd97203901316c5f7d5dc9344525ef 671 SUPERFAMILY SSF51230 595 669 1.7E-21 T 14-10-2018 IPR011053 Single hybrid motif LH59_00555 3dcd97203901316c5f7d5dc9344525ef 671 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 LH59_00555 3dcd97203901316c5f7d5dc9344525ef 671 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 3.9E-41 T 14-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LH59_00555 3dcd97203901316c5f7d5dc9344525ef 671 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 LH59_00555 3dcd97203901316c5f7d5dc9344525ef 671 Gene3D G3DSA:3.30.470.130 1 454 2.1E-200 T 14-10-2018 LH59_00555 3dcd97203901316c5f7d5dc9344525ef 671 Gene3D G3DSA:2.40.50.100 605 670 8.3E-24 T 14-10-2018 LH59_00555 3dcd97203901316c5f7d5dc9344525ef 671 SUPERFAMILY SSF56059 83 348 4.24E-71 T 14-10-2018 LH59_00555 3dcd97203901316c5f7d5dc9344525ef 671 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 322 1.1E-79 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 LH59_00555 3dcd97203901316c5f7d5dc9344525ef 671 SUPERFAMILY SSF52440 1 113 8.63E-45 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily LH59_00555 3dcd97203901316c5f7d5dc9344525ef 671 SUPERFAMILY SSF51246 331 451 1.1E-38 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 LH59_00555 3dcd97203901316c5f7d5dc9344525ef 671 SMART SM01209 114 293 4.1E-4 T 14-10-2018 LH59_00555 3dcd97203901316c5f7d5dc9344525ef 671 SMART SM00878 336 447 2.5E-55 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LH59_02480 0b849af4e7053fc888d9387098301c3b 232 Pfam PF00072 Response regulator receiver domain 5 117 7.1E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_02480 0b849af4e7053fc888d9387098301c3b 232 Gene3D G3DSA:1.10.10.10 127 228 2.8E-38 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_02480 0b849af4e7053fc888d9387098301c3b 232 SMART SM00862 148 225 2.3E-28 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_02480 0b849af4e7053fc888d9387098301c3b 232 TIGRFAM TIGR02154 PhoB: phosphate regulon transcriptional regulatory protein PhoB 1 226 4.9E-113 T 14-10-2018 IPR011879 Signal transduction response regulator, phosphate regulon transcriptional regulatory protein PhoB GO:0000156|GO:0000160|GO:0003677|GO:0006817 LH59_02480 0b849af4e7053fc888d9387098301c3b 232 SMART SM00448 3 116 2.2E-42 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_02480 0b849af4e7053fc888d9387098301c3b 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 225 1.5E-27 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_02480 0b849af4e7053fc888d9387098301c3b 232 SUPERFAMILY SSF52172 3 126 6.97E-43 T 14-10-2018 IPR011006 CheY-like superfamily LH59_02480 0b849af4e7053fc888d9387098301c3b 232 Gene3D G3DSA:3.40.50.2300 1 126 6.2E-39 T 14-10-2018 LH59_02480 0b849af4e7053fc888d9387098301c3b 232 SUPERFAMILY SSF46894 123 226 2.83E-31 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LH59_08545 5705efc9a748eed17113b124b9213c33 446 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 129 140 - T 14-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 LH59_08545 5705efc9a748eed17113b124b9213c33 446 Pfam PF00764 Arginosuccinate synthase 16 394 4.4E-60 T 14-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 LH59_08545 5705efc9a748eed17113b124b9213c33 446 Gene3D G3DSA:1.10.287.400 377 440 3.4E-31 T 14-10-2018 IPR024073 Argininosuccinate synthetase mutimerisation domain, C-terminal tail GO:0042803 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400 LH59_08545 5705efc9a748eed17113b124b9213c33 446 Gene3D G3DSA:3.90.1260.10 74 367 3.6E-119 T 14-10-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 LH59_08545 5705efc9a748eed17113b124b9213c33 446 Hamap MF_00581 Argininosuccinate synthase [argG]. 1 444 68.993 T 14-10-2018 IPR023437 Argininosuccinate synthase, type 2 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400 LH59_08545 5705efc9a748eed17113b124b9213c33 446 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 17 25 - T 14-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 LH59_08545 5705efc9a748eed17113b124b9213c33 446 SUPERFAMILY SSF69864 190 435 3.92E-77 T 14-10-2018 LH59_08545 5705efc9a748eed17113b124b9213c33 446 TIGRFAM TIGR00032 argG: argininosuccinate synthase 13 420 8.4E-159 T 14-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 LH59_08545 5705efc9a748eed17113b124b9213c33 446 Gene3D G3DSA:3.40.50.620 14 191 3.6E-119 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LH59_08545 5705efc9a748eed17113b124b9213c33 446 SUPERFAMILY SSF52402 4 185 9.86E-34 T 14-10-2018 LH59_21900 830f761b80625052f2318e7745704c81 495 PIRSF PIRSF001267 1 494 4.3E-188 T 14-10-2018 IPR030673 Pyrophosphatase, GppA/Ppx-type KEGG: 00230+3.6.1.40 LH59_21900 830f761b80625052f2318e7745704c81 495 Gene3D G3DSA:3.30.420.150 113 292 1.7E-84 T 14-10-2018 LH59_21900 830f761b80625052f2318e7745704c81 495 SUPERFAMILY SSF109604 310 491 4.39E-40 T 14-10-2018 LH59_21900 830f761b80625052f2318e7745704c81 495 Pfam PF02541 Ppx/GppA phosphatase family 28 304 1.1E-75 T 14-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 LH59_21900 830f761b80625052f2318e7745704c81 495 SUPERFAMILY SSF53067 5 130 2.36E-34 T 14-10-2018 LH59_21900 830f761b80625052f2318e7745704c81 495 TIGRFAM TIGR03706 exo_poly_only: exopolyphosphatase 5 303 2.4E-98 T 14-10-2018 IPR022371 Exopolyphosphatase GO:0004309|GO:0006793 LH59_21900 830f761b80625052f2318e7745704c81 495 SUPERFAMILY SSF53067 134 305 9.72E-43 T 14-10-2018 LH59_21900 830f761b80625052f2318e7745704c81 495 Gene3D G3DSA:1.10.3210.10 307 494 2.5E-52 T 14-10-2018 LH59_21900 830f761b80625052f2318e7745704c81 495 Gene3D G3DSA:3.30.420.40 6 300 1.7E-84 T 14-10-2018 LH59_07205 7acb97015597fe127d76e99148e8fe98 366 Gene3D G3DSA:3.40.50.1110 101 216 1.6E-7 T 14-10-2018 IPR036514 SGNH hydrolase superfamily LH59_07205 7acb97015597fe127d76e99148e8fe98 366 Pfam PF16822 SGNH hydrolase-like domain, acetyltransferase AlgX 91 347 1.0E-61 T 14-10-2018 IPR031811 AlgX/AlgJ, SGNH hydrolase-like domain LH59_07205 7acb97015597fe127d76e99148e8fe98 366 SUPERFAMILY SSF52266 115 218 5.5E-7 T 14-10-2018 LH59_11830 7734d751ed2f42cd76a706790a43ffba 288 Pfam PF12796 Ankyrin repeats (3 copies) 28 113 7.7E-7 T 14-10-2018 IPR020683 Ankyrin repeat-containing domain LH59_11830 7734d751ed2f42cd76a706790a43ffba 288 Pfam PF12796 Ankyrin repeats (3 copies) 114 178 6.6E-16 T 14-10-2018 IPR020683 Ankyrin repeat-containing domain LH59_11830 7734d751ed2f42cd76a706790a43ffba 288 PRINTS PR01415 Ankyrin repeat signature 115 130 1.1E-7 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 LH59_11830 7734d751ed2f42cd76a706790a43ffba 288 PRINTS PR01415 Ankyrin repeat signature 163 177 1.1E-7 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 LH59_11830 7734d751ed2f42cd76a706790a43ffba 288 Gene3D G3DSA:1.25.40.20 3 224 5.8E-47 T 14-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily LH59_11830 7734d751ed2f42cd76a706790a43ffba 288 SUPERFAMILY SSF48403 26 200 1.24E-41 T 14-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily LH59_11830 7734d751ed2f42cd76a706790a43ffba 288 SMART SM00248 17 46 1000.0 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 LH59_11830 7734d751ed2f42cd76a706790a43ffba 288 SMART SM00248 114 143 2.5E-5 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 LH59_11830 7734d751ed2f42cd76a706790a43ffba 288 SMART SM00248 84 113 3.5 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 LH59_11830 7734d751ed2f42cd76a706790a43ffba 288 SMART SM00248 147 176 3.3E-5 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 LH59_11830 7734d751ed2f42cd76a706790a43ffba 288 SMART SM00248 50 80 530.0 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 LH59_01780 92d44ed0f48d61d73cfa75ac0fe1eea2 306 Gene3D G3DSA:3.40.190.10 166 265 4.8E-44 T 14-10-2018 LH59_01780 92d44ed0f48d61d73cfa75ac0fe1eea2 306 Pfam PF03466 LysR substrate binding domain 96 296 2.3E-27 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_01780 92d44ed0f48d61d73cfa75ac0fe1eea2 306 SUPERFAMILY SSF53850 96 299 1.12E-29 T 14-10-2018 LH59_01780 92d44ed0f48d61d73cfa75ac0fe1eea2 306 Gene3D G3DSA:1.10.10.10 11 97 4.8E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_01780 92d44ed0f48d61d73cfa75ac0fe1eea2 306 SUPERFAMILY SSF46785 8 90 5.45E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_01780 92d44ed0f48d61d73cfa75ac0fe1eea2 306 Gene3D G3DSA:3.40.190.10 107 292 4.8E-44 T 14-10-2018 LH59_01780 92d44ed0f48d61d73cfa75ac0fe1eea2 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 69 2.3E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_01780 92d44ed0f48d61d73cfa75ac0fe1eea2 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 26 37 5.5E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_01780 92d44ed0f48d61d73cfa75ac0fe1eea2 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 47 58 5.5E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_01780 92d44ed0f48d61d73cfa75ac0fe1eea2 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 47 5.5E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_09145 022df840ee006b133549e39db0f5030c 964 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 898 962 1.1E-21 T 14-10-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 LH59_09145 022df840ee006b133549e39db0f5030c 964 PRINTS PR00986 Valyl-tRNA synthetase signature 524 542 3.0E-35 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 LH59_09145 022df840ee006b133549e39db0f5030c 964 PRINTS PR00986 Valyl-tRNA synthetase signature 57 68 3.0E-35 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 LH59_09145 022df840ee006b133549e39db0f5030c 964 PRINTS PR00986 Valyl-tRNA synthetase signature 264 281 3.0E-35 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 LH59_09145 022df840ee006b133549e39db0f5030c 964 PRINTS PR00986 Valyl-tRNA synthetase signature 493 514 3.0E-35 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 LH59_09145 022df840ee006b133549e39db0f5030c 964 PRINTS PR00986 Valyl-tRNA synthetase signature 380 393 3.0E-35 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 LH59_09145 022df840ee006b133549e39db0f5030c 964 SUPERFAMILY SSF47323 660 913 2.24E-60 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 LH59_09145 022df840ee006b133549e39db0f5030c 964 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 32 649 1.9E-200 T 14-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 LH59_09145 022df840ee006b133549e39db0f5030c 964 Hamap MF_02004 Valine--tRNA ligase [valS]. 19 963 15.395 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 LH59_09145 022df840ee006b133549e39db0f5030c 964 Gene3D G3DSA:1.10.730.10 613 838 9.8E-68 T 14-10-2018 LH59_09145 022df840ee006b133549e39db0f5030c 964 Gene3D G3DSA:3.40.50.620 334 573 5.7E-74 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LH59_09145 022df840ee006b133549e39db0f5030c 964 SUPERFAMILY SSF52374 20 659 6.26E-133 T 14-10-2018 LH59_09145 022df840ee006b133549e39db0f5030c 964 SUPERFAMILY SSF46589 898 962 9.94E-17 T 14-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 LH59_09145 022df840ee006b133549e39db0f5030c 964 Gene3D G3DSA:3.40.50.620 20 222 4.7E-60 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LH59_09145 022df840ee006b133549e39db0f5030c 964 Gene3D G3DSA:1.10.287.380 891 963 3.1E-16 T 14-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 LH59_09145 022df840ee006b133549e39db0f5030c 964 TIGRFAM TIGR00422 valS: valine--tRNA ligase 20 944 0.0 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 LH59_09145 022df840ee006b133549e39db0f5030c 964 Pfam PF08264 Anticodon-binding domain of tRNA 691 843 2.3E-38 T 14-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 LH59_09145 022df840ee006b133549e39db0f5030c 964 SUPERFAMILY SSF50677 212 375 1.31E-57 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 LH59_09145 022df840ee006b133549e39db0f5030c 964 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 64 75 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 LH59_06610 1ad381d5f9fd14b9edbdfe522f6211c2 153 Pfam PF04364 DNA polymerase III chi subunit, HolC 1 141 8.2E-39 T 14-10-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 LH59_06610 1ad381d5f9fd14b9edbdfe522f6211c2 153 SUPERFAMILY SSF102400 1 146 2.48E-39 T 14-10-2018 IPR036768 DNA polymerase III subunit chi superfamily LH59_06610 1ad381d5f9fd14b9edbdfe522f6211c2 153 Gene3D G3DSA:3.40.50.10110 4 146 2.6E-37 T 14-10-2018 IPR036768 DNA polymerase III subunit chi superfamily LH59_17910 a284dac9fcfd4b4dad920ff3ad66a33c 401 ProSitePatterns PS00099 Thiolases active site. 382 395 - T 14-10-2018 IPR020610 Thiolase, active site GO:0016747 LH59_17910 a284dac9fcfd4b4dad920ff3ad66a33c 401 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 399 3.9E-136 T 14-10-2018 IPR002155 Thiolase GO:0016747 LH59_17910 a284dac9fcfd4b4dad920ff3ad66a33c 401 Gene3D G3DSA:3.40.47.10 7 282 2.2E-156 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_17910 a284dac9fcfd4b4dad920ff3ad66a33c 401 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 87 105 - T 14-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 LH59_17910 a284dac9fcfd4b4dad920ff3ad66a33c 401 Gene3D G3DSA:3.40.47.10 142 398 2.2E-156 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_17910 a284dac9fcfd4b4dad920ff3ad66a33c 401 SUPERFAMILY SSF53901 5 276 1.88E-80 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_17910 a284dac9fcfd4b4dad920ff3ad66a33c 401 Pfam PF00108 Thiolase, N-terminal domain 6 268 1.3E-75 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 LH59_17910 a284dac9fcfd4b4dad920ff3ad66a33c 401 TIGRFAM TIGR02430 pcaF: 3-oxoadipyl-CoA thiolase 4 401 6.5E-218 T 14-10-2018 IPR012793 Beta-ketoadipyl CoA thiolase GO:0016747|GO:0019619 KEGG: 00360+2.3.1.174|KEGG: 00362+2.3.1.174|MetaCyc: PWY-1361|MetaCyc: PWY-2361|MetaCyc: PWY-6185 LH59_17910 a284dac9fcfd4b4dad920ff3ad66a33c 401 PIRSF PIRSF000429 1 401 1.4E-131 T 14-10-2018 IPR002155 Thiolase GO:0016747 LH59_17910 a284dac9fcfd4b4dad920ff3ad66a33c 401 Pfam PF02803 Thiolase, C-terminal domain 277 400 1.6E-45 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 LH59_17910 a284dac9fcfd4b4dad920ff3ad66a33c 401 SUPERFAMILY SSF53901 277 400 2.88E-46 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_17910 a284dac9fcfd4b4dad920ff3ad66a33c 401 ProSitePatterns PS00737 Thiolases signature 2. 347 363 - T 14-10-2018 IPR020613 Thiolase, conserved site GO:0016747 LH59_21295 efc2e4e15344ef5cb9cbf82c83511efa 416 Gene3D G3DSA:3.50.50.60 99 408 2.1E-40 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_21295 efc2e4e15344ef5cb9cbf82c83511efa 416 Gene3D G3DSA:3.50.50.60 5 52 2.9E-10 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_21295 efc2e4e15344ef5cb9cbf82c83511efa 416 Pfam PF01266 FAD dependent oxidoreductase 5 397 6.3E-52 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 LH59_21295 efc2e4e15344ef5cb9cbf82c83511efa 416 Gene3D G3DSA:3.30.9.10 135 357 2.1E-40 T 14-10-2018 LH59_21295 efc2e4e15344ef5cb9cbf82c83511efa 416 SUPERFAMILY SSF51905 4 415 1.04E-42 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_03360 75cb19829faf3bf48efbda9c2268af23 237 SMART SM00382 30 231 1.5E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_03360 75cb19829faf3bf48efbda9c2268af23 237 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_03360 75cb19829faf3bf48efbda9c2268af23 237 Pfam PF00005 ABC transporter 22 165 4.5E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_03360 75cb19829faf3bf48efbda9c2268af23 237 SUPERFAMILY SSF52540 5 235 1.33E-55 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_03360 75cb19829faf3bf48efbda9c2268af23 237 Gene3D G3DSA:3.40.50.300 1 237 4.7E-59 T 14-10-2018 LH59_27980 53fa3ce1e1c5fcff34ba4280c4015c5c 126 SUPERFAMILY SSF48300 4 62 1.7E-16 T 14-10-2018 IPR036235 Ribosomal protein L7/L12, oligomerisation domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_27980 53fa3ce1e1c5fcff34ba4280c4015c5c 126 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 60 126 5.0E-31 T 14-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_27980 53fa3ce1e1c5fcff34ba4280c4015c5c 126 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 62 99 8.0E-14 T 14-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_27980 53fa3ce1e1c5fcff34ba4280c4015c5c 126 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 126 6.6E-49 T 14-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_27980 53fa3ce1e1c5fcff34ba4280c4015c5c 126 Gene3D G3DSA:1.20.5.710 3 55 7.0E-21 T 14-10-2018 LH59_27980 53fa3ce1e1c5fcff34ba4280c4015c5c 126 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 5 52 2.2E-19 T 14-10-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_27980 53fa3ce1e1c5fcff34ba4280c4015c5c 126 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 2 126 26.04 T 14-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_27980 53fa3ce1e1c5fcff34ba4280c4015c5c 126 Gene3D G3DSA:3.30.1390.10 56 126 3.7E-31 T 14-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like LH59_27980 53fa3ce1e1c5fcff34ba4280c4015c5c 126 SUPERFAMILY SSF54736 55 126 1.26E-24 T 14-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like LH59_02380 2ffa84d237031bded9336bcc3c76f2fd 423 PIRSF PIRSF000443 14 412 3.3E-143 T 14-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 LH59_02380 2ffa84d237031bded9336bcc3c76f2fd 423 Gene3D G3DSA:1.10.1740.110 213 322 4.4E-138 T 14-10-2018 LH59_02380 2ffa84d237031bded9336bcc3c76f2fd 423 Gene3D G3DSA:3.40.50.1820 54 392 4.4E-138 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_02380 2ffa84d237031bded9336bcc3c76f2fd 423 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 48 402 3.1E-138 T 14-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 LH59_02380 2ffa84d237031bded9336bcc3c76f2fd 423 Pfam PF00561 alpha/beta hydrolase fold 77 391 7.4E-35 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_02380 2ffa84d237031bded9336bcc3c76f2fd 423 Hamap MF_00296 Homoserine O-acetyltransferase [metXA]. 40 404 30.137 T 14-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 LH59_02380 2ffa84d237031bded9336bcc3c76f2fd 423 SUPERFAMILY SSF53474 41 401 1.17E-102 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_12765 d4e88155e6770636c7429674cd4d6457 301 PIRSF PIRSF006232 9 291 1.1E-89 T 14-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 LH59_12765 d4e88155e6770636c7429674cd4d6457 301 Pfam PF05726 Pirin C-terminal cupin domain 184 283 2.2E-26 T 14-10-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 LH59_12765 d4e88155e6770636c7429674cd4d6457 301 Gene3D G3DSA:2.60.120.10 25 278 3.9E-73 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_12765 d4e88155e6770636c7429674cd4d6457 301 SUPERFAMILY SSF51182 13 286 6.32E-83 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_12765 d4e88155e6770636c7429674cd4d6457 301 Pfam PF02678 Pirin 26 131 1.8E-35 T 14-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 LH59_12765 d4e88155e6770636c7429674cd4d6457 301 Gene3D G3DSA:2.60.120.10 153 252 3.9E-73 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_21990 7c0e672222b0266bd9988f9972bc4df4 298 Pfam PF05118 Aspartyl/Asparaginyl beta-hydroxylase 71 222 1.6E-45 T 14-10-2018 IPR007803 Aspartyl/asparaginy/proline hydroxylase GO:0018193 LH59_21990 7c0e672222b0266bd9988f9972bc4df4 298 SUPERFAMILY SSF51197 97 224 2.75E-19 T 14-10-2018 LH59_21990 7c0e672222b0266bd9988f9972bc4df4 298 Gene3D G3DSA:2.60.120.330 43 228 3.6E-43 T 14-10-2018 IPR027443 Isopenicillin N synthase-like LH59_04445 91ff9d00dda8dc97abef5067519cc8b0 255 Gene3D G3DSA:1.10.12.10 198 255 3.5E-21 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal LH59_04445 91ff9d00dda8dc97abef5067519cc8b0 255 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 96 116 - T 14-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 LH59_04445 91ff9d00dda8dc97abef5067519cc8b0 255 Gene3D G3DSA:3.90.226.10 1 197 1.0E-68 T 14-10-2018 LH59_04445 91ff9d00dda8dc97abef5067519cc8b0 255 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 251 1.8E-55 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 LH59_04445 91ff9d00dda8dc97abef5067519cc8b0 255 SUPERFAMILY SSF52096 1 254 1.72E-77 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily LH59_16025 9b380f6537f3b466454080b16cd6f199 295 Gene3D G3DSA:3.20.20.220 19 283 2.9E-27 T 14-10-2018 LH59_16025 9b380f6537f3b466454080b16cd6f199 295 Pfam PF02219 Methylenetetrahydrofolate reductase 51 223 2.5E-7 T 14-10-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 LH59_16025 9b380f6537f3b466454080b16cd6f199 295 SUPERFAMILY SSF51730 20 281 2.35E-44 T 14-10-2018 IPR029041 FAD-linked oxidoreductase-like LH59_17215 f23d7edfed771dfb052d3c46c40a3464 216 SUPERFAMILY SSF46785 4 71 3.46E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_17215 f23d7edfed771dfb052d3c46c40a3464 216 Pfam PF00717 Peptidase S24-like 129 191 6.6E-16 T 14-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C LH59_17215 f23d7edfed771dfb052d3c46c40a3464 216 SUPERFAMILY SSF51306 90 211 2.27E-34 T 14-10-2018 IPR036286 LexA/Signal peptidase-like superfamily LH59_17215 f23d7edfed771dfb052d3c46c40a3464 216 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 126 136 2.1E-10 T 14-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 LH59_17215 f23d7edfed771dfb052d3c46c40a3464 216 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 137 148 2.1E-10 T 14-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 LH59_17215 f23d7edfed771dfb052d3c46c40a3464 216 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 165 177 2.1E-10 T 14-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 LH59_17215 f23d7edfed771dfb052d3c46c40a3464 216 TIGRFAM TIGR00498 lexA: repressor LexA 3 211 6.4E-69 T 14-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 LH59_17215 f23d7edfed771dfb052d3c46c40a3464 216 Gene3D G3DSA:2.10.109.10 95 214 1.0E-39 T 14-10-2018 LH59_17215 f23d7edfed771dfb052d3c46c40a3464 216 Gene3D G3DSA:1.10.10.10 2 70 1.1E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_17215 f23d7edfed771dfb052d3c46c40a3464 216 Hamap MF_00015 LexA repressor [lexA]. 4 213 31.953 T 14-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 LH59_17215 f23d7edfed771dfb052d3c46c40a3464 216 Pfam PF01726 LexA DNA binding domain 3 66 1.5E-27 T 14-10-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 LH59_15045 7bfa9b8f0eb0ee939632c1d25126fe3a 325 SUPERFAMILY SSF160240 227 305 2.22E-21 T 14-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 LH59_15045 7bfa9b8f0eb0ee939632c1d25126fe3a 325 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 27 303 4.0E-66 T 14-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 LH59_15045 7bfa9b8f0eb0ee939632c1d25126fe3a 325 Pfam PF16916 Dimerisation domain of Zinc Transporter 228 303 6.4E-22 T 14-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain LH59_15045 7bfa9b8f0eb0ee939632c1d25126fe3a 325 Pfam PF01545 Cation efflux family 30 223 3.7E-43 T 14-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 LH59_15045 7bfa9b8f0eb0ee939632c1d25126fe3a 325 SUPERFAMILY SSF161111 25 224 1.31E-52 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily LH59_15045 7bfa9b8f0eb0ee939632c1d25126fe3a 325 Gene3D G3DSA:1.20.1510.10 25 223 5.5E-58 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily LH59_15045 7bfa9b8f0eb0ee939632c1d25126fe3a 325 Gene3D G3DSA:3.30.70.1350 224 305 4.3E-21 T 14-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 LH59_13910 42395598c8640a0bc5498710479f6755 401 Gene3D G3DSA:3.40.640.10 54 312 5.0E-101 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_13910 42395598c8640a0bc5498710479f6755 401 SUPERFAMILY SSF53383 28 399 8.53E-77 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_13910 42395598c8640a0bc5498710479f6755 401 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 226 246 - T 14-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site LH59_13910 42395598c8640a0bc5498710479f6755 401 Pfam PF00266 Aminotransferase class-V 44 379 4.9E-47 T 14-10-2018 IPR000192 Aminotransferase class V domain LH59_13910 42395598c8640a0bc5498710479f6755 401 Gene3D G3DSA:3.90.1150.10 40 396 5.0E-101 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_19605 4b192b93f53a84b85a9723b853a6dd35 285 SUPERFAMILY SSF52518 10 278 3.84E-77 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold LH59_19605 4b192b93f53a84b85a9723b853a6dd35 285 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 20 264 3.5E-42 T 14-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 LH59_19605 4b192b93f53a84b85a9723b853a6dd35 285 Gene3D G3DSA:3.40.50.970 7 284 2.1E-89 T 14-10-2018 LH59_04970 d7fbbb7e595b4059d44d530882fcd177 588 SUPERFAMILY SSF50715 374 584 4.6E-66 T 14-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 LH59_04970 d7fbbb7e595b4059d44d530882fcd177 588 PRINTS PR00987 Glutamyl-tRNA synthetase signature 70 81 8.2E-10 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 LH59_04970 d7fbbb7e595b4059d44d530882fcd177 588 PRINTS PR00987 Glutamyl-tRNA synthetase signature 239 249 8.2E-10 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 LH59_04970 d7fbbb7e595b4059d44d530882fcd177 588 PRINTS PR00987 Glutamyl-tRNA synthetase signature 85 98 8.2E-10 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 LH59_04970 d7fbbb7e595b4059d44d530882fcd177 588 PRINTS PR00987 Glutamyl-tRNA synthetase signature 56 68 8.2E-10 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 LH59_04970 d7fbbb7e595b4059d44d530882fcd177 588 Hamap MF_00126 Glutamine--tRNA ligase [glnS]. 1 585 51.746 T 14-10-2018 IPR022861 Glutamine-tRNA ligase, bacterial GO:0004819 KEGG: 00970+6.1.1.18 LH59_04970 d7fbbb7e595b4059d44d530882fcd177 588 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 59 70 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 LH59_04970 d7fbbb7e595b4059d44d530882fcd177 588 Gene3D G3DSA:3.40.50.620 54 277 1.2E-97 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LH59_04970 d7fbbb7e595b4059d44d530882fcd177 588 SUPERFAMILY SSF52374 52 379 9.65E-96 T 14-10-2018 LH59_04970 d7fbbb7e595b4059d44d530882fcd177 588 Gene3D G3DSA:2.40.240.10 374 582 2.7E-70 T 14-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 LH59_04970 d7fbbb7e595b4059d44d530882fcd177 588 TIGRFAM TIGR00440 glnS: glutamine--tRNA ligase 53 585 8.3E-205 T 14-10-2018 IPR004514 Glutamine-tRNA synthetase GO:0000166|GO:0004819|GO:0005524|GO:0005737|GO:0006425 KEGG: 00970+6.1.1.18|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 LH59_04970 d7fbbb7e595b4059d44d530882fcd177 588 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 52 371 6.4E-101 T 14-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 LH59_04970 d7fbbb7e595b4059d44d530882fcd177 588 Gene3D G3DSA:1.10.1160.10 295 372 5.4E-30 T 14-10-2018 IPR020061 Glutamine-tRNA ligase, alpha-bundle domain superfamily GO:0005524 LH59_04970 d7fbbb7e595b4059d44d530882fcd177 588 Gene3D G3DSA:2.40.240.10 382 501 2.7E-70 T 14-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 LH59_04970 d7fbbb7e595b4059d44d530882fcd177 588 Gene3D G3DSA:3.90.800.10 130 238 1.2E-97 T 14-10-2018 LH59_04970 d7fbbb7e595b4059d44d530882fcd177 588 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 374 564 3.3E-49 T 14-10-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 LH59_21915 10b5dc069d84df31ff14c61a98118093 447 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 4 138 4.2E-42 T 14-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LH59_21915 10b5dc069d84df31ff14c61a98118093 447 SUPERFAMILY SSF53738 264 371 1.88E-28 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LH59_21915 10b5dc069d84df31ff14c61a98118093 447 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 378 444 8.4E-13 T 14-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LH59_21915 10b5dc069d84df31ff14c61a98118093 447 Gene3D G3DSA:3.40.120.10 3 158 3.4E-48 T 14-10-2018 LH59_21915 10b5dc069d84df31ff14c61a98118093 447 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 101 115 4.9E-12 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LH59_21915 10b5dc069d84df31ff14c61a98118093 447 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 180 199 4.9E-12 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LH59_21915 10b5dc069d84df31ff14c61a98118093 447 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 240 255 4.9E-12 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LH59_21915 10b5dc069d84df31ff14c61a98118093 447 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 163 260 5.9E-17 T 14-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LH59_21915 10b5dc069d84df31ff14c61a98118093 447 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 3 445 44.628 T 14-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LH59_21915 10b5dc069d84df31ff14c61a98118093 447 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 7 444 5.0E-173 T 14-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LH59_21915 10b5dc069d84df31ff14c61a98118093 447 SUPERFAMILY SSF55957 363 444 3.27E-20 T 14-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LH59_21915 10b5dc069d84df31ff14c61a98118093 447 Gene3D G3DSA:3.30.310.50 375 447 2.3E-20 T 14-10-2018 LH59_21915 10b5dc069d84df31ff14c61a98118093 447 SUPERFAMILY SSF53738 162 262 1.14E-27 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LH59_21915 10b5dc069d84df31ff14c61a98118093 447 Gene3D G3DSA:3.40.120.10 263 344 5.4E-56 T 14-10-2018 LH59_21915 10b5dc069d84df31ff14c61a98118093 447 Gene3D G3DSA:3.40.120.10 180 365 5.4E-56 T 14-10-2018 LH59_21915 10b5dc069d84df31ff14c61a98118093 447 SUPERFAMILY SSF53738 2 187 8.24E-47 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LH59_21915 10b5dc069d84df31ff14c61a98118093 447 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 264 371 1.6E-27 T 14-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LH59_21915 10b5dc069d84df31ff14c61a98118093 447 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 102 111 - T 14-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LH59_11185 dba77f75cdc052a684dae0b054b4c767 243 Pfam PF01479 S4 domain 4 41 2.2E-6 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_11185 dba77f75cdc052a684dae0b054b4c767 243 SUPERFAMILY SSF55120 65 241 3.2E-37 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 LH59_11185 dba77f75cdc052a684dae0b054b4c767 243 Gene3D G3DSA:3.30.2350.10 60 242 5.1E-45 T 14-10-2018 LH59_11185 dba77f75cdc052a684dae0b054b4c767 243 Pfam PF00849 RNA pseudouridylate synthase 66 161 1.1E-8 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 LH59_11185 dba77f75cdc052a684dae0b054b4c767 243 Gene3D G3DSA:3.10.290.10 1 56 1.3E-15 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 LH59_11185 dba77f75cdc052a684dae0b054b4c767 243 SMART SM00363 4 61 3.7E-4 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_11185 dba77f75cdc052a684dae0b054b4c767 243 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 109 238 7.1E-36 T 14-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 LH59_11185 dba77f75cdc052a684dae0b054b4c767 243 SUPERFAMILY SSF55174 3 84 9.55E-13 T 14-10-2018 LH59_12090 78da763e3d8048af0cb97589d698a5b6 270 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 259 4.0E-12 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_12090 78da763e3d8048af0cb97589d698a5b6 270 Gene3D G3DSA:1.10.3720.10 2 263 1.1E-53 T 14-10-2018 IPR035906 MetI-like superfamily LH59_12090 78da763e3d8048af0cb97589d698a5b6 270 SUPERFAMILY SSF161098 6 269 7.46E-64 T 14-10-2018 IPR035906 MetI-like superfamily LH59_05315 27cc74e927cee9a0ab722af95686f445 641 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 LH59_05315 27cc74e927cee9a0ab722af95686f445 641 Gene3D G3DSA:1.20.1270.10 525 608 1.0E-25 T 14-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 LH59_05315 27cc74e927cee9a0ab722af95686f445 641 Gene3D G3DSA:3.30.420.40 5 380 1.0E-166 T 14-10-2018 LH59_05315 27cc74e927cee9a0ab722af95686f445 641 Gene3D G3DSA:3.30.420.40 180 367 1.0E-166 T 14-10-2018 LH59_05315 27cc74e927cee9a0ab722af95686f445 641 SUPERFAMILY SSF100920 385 541 4.05E-61 T 14-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 LH59_05315 27cc74e927cee9a0ab722af95686f445 641 PRINTS PR00301 70kDa heat shock protein signature 3 16 1.4E-80 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LH59_05315 27cc74e927cee9a0ab722af95686f445 641 PRINTS PR00301 70kDa heat shock protein signature 31 43 1.4E-80 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LH59_05315 27cc74e927cee9a0ab722af95686f445 641 PRINTS PR00301 70kDa heat shock protein signature 470 486 1.4E-80 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LH59_05315 27cc74e927cee9a0ab722af95686f445 641 PRINTS PR00301 70kDa heat shock protein signature 199 209 1.4E-80 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LH59_05315 27cc74e927cee9a0ab722af95686f445 641 PRINTS PR00301 70kDa heat shock protein signature 335 351 1.4E-80 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LH59_05315 27cc74e927cee9a0ab722af95686f445 641 PRINTS PR00301 70kDa heat shock protein signature 366 386 1.4E-80 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LH59_05315 27cc74e927cee9a0ab722af95686f445 641 PRINTS PR00301 70kDa heat shock protein signature 54 62 1.4E-80 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LH59_05315 27cc74e927cee9a0ab722af95686f445 641 PRINTS PR00301 70kDa heat shock protein signature 138 158 1.4E-80 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LH59_05315 27cc74e927cee9a0ab722af95686f445 641 PRINTS PR00301 70kDa heat shock protein signature 389 408 1.4E-80 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LH59_05315 27cc74e927cee9a0ab722af95686f445 641 SUPERFAMILY SSF100934 508 610 2.75E-20 T 14-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 LH59_05315 27cc74e927cee9a0ab722af95686f445 641 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 604 1.3E-291 T 14-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 LH59_05315 27cc74e927cee9a0ab722af95686f445 641 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 637 37.134 T 14-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 LH59_05315 27cc74e927cee9a0ab722af95686f445 641 Gene3D G3DSA:2.60.34.10 384 524 9.5E-67 T 14-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 LH59_05315 27cc74e927cee9a0ab722af95686f445 641 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 338 352 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 LH59_05315 27cc74e927cee9a0ab722af95686f445 641 Gene3D G3DSA:3.90.640.10 230 317 1.0E-166 T 14-10-2018 LH59_05315 27cc74e927cee9a0ab722af95686f445 641 Pfam PF00012 Hsp70 protein 4 604 8.1E-267 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LH59_05315 27cc74e927cee9a0ab722af95686f445 641 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 193 206 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 LH59_05315 27cc74e927cee9a0ab722af95686f445 641 SUPERFAMILY SSF53067 188 383 1.69E-68 T 14-10-2018 LH59_05315 27cc74e927cee9a0ab722af95686f445 641 SUPERFAMILY SSF53067 4 184 5.34E-66 T 14-10-2018 LH59_12050 e8ce2481b33364dd211be9f50f966ecf 345 Gene3D G3DSA:3.40.50.720 130 311 8.4E-127 T 14-10-2018 LH59_12050 e8ce2481b33364dd211be9f50f966ecf 345 Pfam PF16884 N-terminal domain of oxidoreductase 9 115 1.2E-42 T 14-10-2018 LH59_12050 e8ce2481b33364dd211be9f50f966ecf 345 Gene3D G3DSA:3.90.180.10 19 339 8.4E-127 T 14-10-2018 LH59_12050 e8ce2481b33364dd211be9f50f966ecf 345 SUPERFAMILY SSF50129 7 146 1.09E-42 T 14-10-2018 IPR011032 GroES-like superfamily LH59_12050 e8ce2481b33364dd211be9f50f966ecf 345 SUPERFAMILY SSF51735 127 304 2.5E-44 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_12050 e8ce2481b33364dd211be9f50f966ecf 345 Pfam PF00107 Zinc-binding dehydrogenase 161 303 2.5E-20 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 LH59_03585 7d3001473c0c471c33833de4cf72ae38 259 Pfam PF08241 Methyltransferase domain 80 131 1.9E-8 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 LH59_03585 7d3001473c0c471c33833de4cf72ae38 259 SUPERFAMILY SSF53335 79 200 3.38E-15 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_03585 7d3001473c0c471c33833de4cf72ae38 259 Gene3D G3DSA:3.40.50.150 12 194 1.1E-16 T 14-10-2018 LH59_18250 259d1ed81216ed624a7afa0eed493656 710 Pfam PF00593 TonB dependent receptor 241 708 1.1E-58 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_18250 259d1ed81216ed624a7afa0eed493656 710 Gene3D G3DSA:2.170.130.10 47 174 1.4E-33 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily LH59_18250 259d1ed81216ed624a7afa0eed493656 710 SUPERFAMILY SSF56935 32 709 2.85E-132 T 14-10-2018 LH59_18250 259d1ed81216ed624a7afa0eed493656 710 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 70 708 1.3E-139 T 14-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 LH59_18250 259d1ed81216ed624a7afa0eed493656 710 Gene3D G3DSA:2.40.170.20 175 710 4.8E-202 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_18250 259d1ed81216ed624a7afa0eed493656 710 Pfam PF07715 TonB-dependent Receptor Plug Domain 68 166 5.2E-12 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_11155 597b3acbb2f54f2037100c7f0a632505 622 SMART SM00382 38 243 3.4E-18 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_11155 597b3acbb2f54f2037100c7f0a632505 622 SMART SM00382 352 544 1.6E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_11155 597b3acbb2f54f2037100c7f0a632505 622 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_11155 597b3acbb2f54f2037100c7f0a632505 622 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 245 275 6.6E-7 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_11155 597b3acbb2f54f2037100c7f0a632505 622 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 546 578 5.7E-9 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_11155 597b3acbb2f54f2037100c7f0a632505 622 SUPERFAMILY SSF52540 9 265 1.85E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_11155 597b3acbb2f54f2037100c7f0a632505 622 Pfam PF00005 ABC transporter 30 193 2.6E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_11155 597b3acbb2f54f2037100c7f0a632505 622 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 544 593 3.1E-10 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_11155 597b3acbb2f54f2037100c7f0a632505 622 SUPERFAMILY SSF52540 317 566 5.11E-71 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_11155 597b3acbb2f54f2037100c7f0a632505 622 Pfam PF00005 ABC transporter 344 493 1.1E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_11155 597b3acbb2f54f2037100c7f0a632505 622 Gene3D G3DSA:3.40.50.300 7 310 2.9E-82 T 14-10-2018 LH59_11155 597b3acbb2f54f2037100c7f0a632505 622 Gene3D G3DSA:3.40.50.300 314 617 1.4E-85 T 14-10-2018 LH59_11155 597b3acbb2f54f2037100c7f0a632505 622 ProSitePatterns PS00211 ABC transporters family signature. 467 481 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_03550 5d4574f5ce277c2ddac6a311ffc4c0fb 292 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 126 291 2.1E-58 T 14-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 LH59_03550 5d4574f5ce277c2ddac6a311ffc4c0fb 292 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 26 291 5.1E-97 T 14-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 LH59_03550 5d4574f5ce277c2ddac6a311ffc4c0fb 292 Gene3D G3DSA:3.20.20.70 129 282 5.5E-101 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_03550 5d4574f5ce277c2ddac6a311ffc4c0fb 292 PIRSF PIRSF006250 19 292 1.8E-91 T 14-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 LH59_03550 5d4574f5ce277c2ddac6a311ffc4c0fb 292 SUPERFAMILY SSF51690 126 291 2.2E-56 T 14-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 LH59_03550 5d4574f5ce277c2ddac6a311ffc4c0fb 292 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 37 124 3.1E-25 T 14-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 LH59_03550 5d4574f5ce277c2ddac6a311ffc4c0fb 292 SUPERFAMILY SSF54675 13 125 3.06E-32 T 14-10-2018 LH59_03550 5d4574f5ce277c2ddac6a311ffc4c0fb 292 Gene3D G3DSA:3.90.1170.20 28 291 5.5E-101 T 14-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 LH59_20515 b1d3e0eaaa36e8674d061ec15de12bb0 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 8.0E-19 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_20515 b1d3e0eaaa36e8674d061ec15de12bb0 305 Gene3D G3DSA:3.40.190.290 91 293 2.3E-60 T 14-10-2018 LH59_20515 b1d3e0eaaa36e8674d061ec15de12bb0 305 SUPERFAMILY SSF53850 90 297 2.79E-47 T 14-10-2018 LH59_20515 b1d3e0eaaa36e8674d061ec15de12bb0 305 Gene3D G3DSA:1.10.10.10 2 85 7.9E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_20515 b1d3e0eaaa36e8674d061ec15de12bb0 305 SUPERFAMILY SSF46785 2 112 5.44E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_20515 b1d3e0eaaa36e8674d061ec15de12bb0 305 Pfam PF03466 LysR substrate binding domain 89 294 5.3E-45 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_07255 95697333bbb86baddcfe0ee489af0c32 197 ProSitePatterns PS01068 OmpA-like domain. 124 168 - T 14-10-2018 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 LH59_07255 95697333bbb86baddcfe0ee489af0c32 197 Gene3D G3DSA:3.30.1330.60 69 197 1.5E-45 T 14-10-2018 IPR036737 OmpA-like domain superfamily LH59_07255 95697333bbb86baddcfe0ee489af0c32 197 SUPERFAMILY SSF103088 83 192 7.85E-41 T 14-10-2018 IPR036737 OmpA-like domain superfamily LH59_07255 95697333bbb86baddcfe0ee489af0c32 197 Pfam PF00691 OmpA family 91 186 9.0E-27 T 14-10-2018 IPR006665 OmpA-like domain LH59_07255 95697333bbb86baddcfe0ee489af0c32 197 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 155 174 8.1E-9 T 14-10-2018 LH59_07255 95697333bbb86baddcfe0ee489af0c32 197 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 137 154 8.1E-9 T 14-10-2018 LH59_07255 95697333bbb86baddcfe0ee489af0c32 197 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 175 195 8.1E-9 T 14-10-2018 LH59_07255 95697333bbb86baddcfe0ee489af0c32 197 PRINTS PR01021 OMPA domain signature 122 137 5.8E-23 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 LH59_07255 95697333bbb86baddcfe0ee489af0c32 197 PRINTS PR01021 OMPA domain signature 137 153 5.8E-23 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 LH59_07255 95697333bbb86baddcfe0ee489af0c32 197 PRINTS PR01021 OMPA domain signature 92 114 5.8E-23 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 LH59_17680 b1e0eef93ce2cd45ffc68ed4c87a50b9 459 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 188 202 3.2E-27 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase LH59_17680 b1e0eef93ce2cd45ffc68ed4c87a50b9 459 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 217 227 3.2E-27 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase LH59_17680 b1e0eef93ce2cd45ffc68ed4c87a50b9 459 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 390 407 3.2E-27 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase LH59_17680 b1e0eef93ce2cd45ffc68ed4c87a50b9 459 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 286 298 3.2E-27 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase LH59_17680 b1e0eef93ce2cd45ffc68ed4c87a50b9 459 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 336 352 3.2E-27 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase LH59_17680 b1e0eef93ce2cd45ffc68ed4c87a50b9 459 Pfam PF01189 16S rRNA methyltransferase RsmB/F 206 405 1.3E-46 T 14-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 LH59_17680 b1e0eef93ce2cd45ffc68ed4c87a50b9 459 SUPERFAMILY SSF53335 103 407 1.41E-66 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_17680 b1e0eef93ce2cd45ffc68ed4c87a50b9 459 Gene3D G3DSA:3.40.50.150 108 407 4.0E-79 T 14-10-2018 LH59_23845 c3dfb5b83aeba09c80aaa27e1269b121 319 SUPERFAMILY SSF51679 42 301 1.85E-46 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 LH59_23845 c3dfb5b83aeba09c80aaa27e1269b121 319 Pfam PF00296 Luciferase-like monooxygenase 33 228 7.0E-32 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LH59_23845 c3dfb5b83aeba09c80aaa27e1269b121 319 TIGRFAM TIGR03571 lucif_BA3436: luciferase-type oxidoreductase, BA3436 family 9 304 9.0E-102 T 14-10-2018 IPR020020 Luciferase-type oxidoreductase LH59_23845 c3dfb5b83aeba09c80aaa27e1269b121 319 Gene3D G3DSA:3.20.20.30 8 306 6.2E-71 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 LH59_13770 279d99067d47bee2ebc7108fd8917e7b 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 59 2.5E-19 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_13770 279d99067d47bee2ebc7108fd8917e7b 205 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 58 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site LH59_13770 279d99067d47bee2ebc7108fd8917e7b 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 1.2E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_13770 279d99067d47bee2ebc7108fd8917e7b 205 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 1.2E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_13770 279d99067d47bee2ebc7108fd8917e7b 205 Gene3D G3DSA:1.10.357.10 63 202 6.1E-35 T 14-10-2018 LH59_13770 279d99067d47bee2ebc7108fd8917e7b 205 SUPERFAMILY SSF46689 5 84 1.15E-21 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_13770 279d99067d47bee2ebc7108fd8917e7b 205 Gene3D G3DSA:1.10.10.60 5 60 7.1E-28 T 14-10-2018 LH59_13770 279d99067d47bee2ebc7108fd8917e7b 205 Pfam PF14246 AefR-like transcriptional repressor, C-terminal region 147 201 9.6E-21 T 14-10-2018 IPR039536 Transcriptional regulator TetR, C-terminal, Proteobacteria type LH59_13770 279d99067d47bee2ebc7108fd8917e7b 205 SUPERFAMILY SSF48498 84 201 1.68E-13 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily LH59_15315 f94788ed327e0b2bbc815177b0c47715 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 3.7E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_15315 f94788ed327e0b2bbc815177b0c47715 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 3.7E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_15315 f94788ed327e0b2bbc815177b0c47715 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 3.7E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_15315 f94788ed327e0b2bbc815177b0c47715 291 Gene3D G3DSA:3.40.190.290 92 289 2.0E-36 T 14-10-2018 LH59_15315 f94788ed327e0b2bbc815177b0c47715 291 SUPERFAMILY SSF46785 1 112 1.41E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_15315 f94788ed327e0b2bbc815177b0c47715 291 Gene3D G3DSA:1.10.10.10 1 89 1.5E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_15315 f94788ed327e0b2bbc815177b0c47715 291 SUPERFAMILY SSF53850 90 287 3.41E-32 T 14-10-2018 LH59_15315 f94788ed327e0b2bbc815177b0c47715 291 Pfam PF03466 LysR substrate binding domain 88 286 2.3E-35 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_15315 f94788ed327e0b2bbc815177b0c47715 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 4.2E-19 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_02485 527a21a626d3c5f3723e7f88e1b0972e 258 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 165 179 - T 14-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 LH59_02485 527a21a626d3c5f3723e7f88e1b0972e 258 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 25 256 35.692 T 14-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 LH59_02485 527a21a626d3c5f3723e7f88e1b0972e 258 Pfam PF01209 ubiE/COQ5 methyltransferase family 30 255 1.9E-82 T 14-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 LH59_02485 527a21a626d3c5f3723e7f88e1b0972e 258 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 45 60 - T 14-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 LH59_02485 527a21a626d3c5f3723e7f88e1b0972e 258 Gene3D G3DSA:3.40.50.150 40 257 6.4E-67 T 14-10-2018 LH59_02485 527a21a626d3c5f3723e7f88e1b0972e 258 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 34 254 8.9E-74 T 14-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 LH59_02485 527a21a626d3c5f3723e7f88e1b0972e 258 SUPERFAMILY SSF53335 18 248 8.13E-45 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_16395 13f93d1d817117acd733acd53cf00d6e 710 Pfam PF07715 TonB-dependent Receptor Plug Domain 68 168 7.7E-20 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_16395 13f93d1d817117acd733acd53cf00d6e 710 SUPERFAMILY SSF56935 25 710 3.55E-138 T 14-10-2018 LH59_16395 13f93d1d817117acd733acd53cf00d6e 710 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 70 710 5.5E-115 T 14-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 LH59_16395 13f93d1d817117acd733acd53cf00d6e 710 Pfam PF00593 TonB dependent receptor 252 709 5.1E-60 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_16395 13f93d1d817117acd733acd53cf00d6e 710 Gene3D G3DSA:2.40.170.20 178 710 5.3E-136 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_16395 13f93d1d817117acd733acd53cf00d6e 710 Gene3D G3DSA:2.170.130.10 45 177 8.4E-40 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily LH59_14830 6e279385bbdaaa14cc6e34ef4038feb1 507 SMART SM00345 31 90 3.0E-10 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_14830 6e279385bbdaaa14cc6e34ef4038feb1 507 Pfam PF00392 Bacterial regulatory proteins, gntR family 28 90 6.6E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_14830 6e279385bbdaaa14cc6e34ef4038feb1 507 SUPERFAMILY SSF46785 23 93 2.5E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_14830 6e279385bbdaaa14cc6e34ef4038feb1 507 Gene3D G3DSA:1.10.10.10 24 93 1.0E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_14830 6e279385bbdaaa14cc6e34ef4038feb1 507 Gene3D G3DSA:3.40.640.10 129 493 9.9E-94 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_14830 6e279385bbdaaa14cc6e34ef4038feb1 507 Pfam PF00155 Aminotransferase class I and II 200 481 8.8E-16 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LH59_14830 6e279385bbdaaa14cc6e34ef4038feb1 507 SUPERFAMILY SSF53383 118 501 4.13E-76 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_28080 12b611fe11ca1f94187f0008e1f4fb87 531 Pfam PF00581 Rhodanese-like domain 280 362 7.1E-6 T 14-10-2018 IPR001763 Rhodanese-like domain LH59_28080 12b611fe11ca1f94187f0008e1f4fb87 531 Pfam PF00581 Rhodanese-like domain 18 108 3.9E-10 T 14-10-2018 IPR001763 Rhodanese-like domain LH59_28080 12b611fe11ca1f94187f0008e1f4fb87 531 Pfam PF00581 Rhodanese-like domain 139 232 4.6E-10 T 14-10-2018 IPR001763 Rhodanese-like domain LH59_28080 12b611fe11ca1f94187f0008e1f4fb87 531 SMART SM00450 380 473 7.5 T 14-10-2018 IPR001763 Rhodanese-like domain LH59_28080 12b611fe11ca1f94187f0008e1f4fb87 531 SMART SM00450 275 371 3.7E-4 T 14-10-2018 IPR001763 Rhodanese-like domain LH59_28080 12b611fe11ca1f94187f0008e1f4fb87 531 SMART SM00450 138 236 6.3E-9 T 14-10-2018 IPR001763 Rhodanese-like domain LH59_28080 12b611fe11ca1f94187f0008e1f4fb87 531 SMART SM00450 14 112 1.1E-11 T 14-10-2018 IPR001763 Rhodanese-like domain LH59_28080 12b611fe11ca1f94187f0008e1f4fb87 531 Gene3D G3DSA:3.40.250.10 10 116 2.8E-20 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily LH59_28080 12b611fe11ca1f94187f0008e1f4fb87 531 Gene3D G3DSA:3.40.250.10 134 241 1.4E-20 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily LH59_28080 12b611fe11ca1f94187f0008e1f4fb87 531 SUPERFAMILY SSF52821 11 126 3.27E-24 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily LH59_28080 12b611fe11ca1f94187f0008e1f4fb87 531 SUPERFAMILY SSF52821 264 363 7.2E-22 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily LH59_28080 12b611fe11ca1f94187f0008e1f4fb87 531 SUPERFAMILY SSF52821 377 527 1.7E-16 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily LH59_28080 12b611fe11ca1f94187f0008e1f4fb87 531 Gene3D G3DSA:3.40.250.10 380 478 9.1E-10 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily LH59_28080 12b611fe11ca1f94187f0008e1f4fb87 531 SUPERFAMILY SSF52821 114 242 7.2E-30 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily LH59_28080 12b611fe11ca1f94187f0008e1f4fb87 531 Gene3D G3DSA:3.40.250.10 272 359 3.2E-19 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily LH59_16700 5acf5fcd1883a72c89c589cc1552b682 263 Gene3D G3DSA:3.20.20.70 1 263 2.4E-88 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_16700 5acf5fcd1883a72c89c589cc1552b682 263 Pfam PF00290 Tryptophan synthase alpha chain 9 242 1.4E-76 T 14-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 LH59_16700 5acf5fcd1883a72c89c589cc1552b682 263 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 48 61 - T 14-10-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 LH59_16700 5acf5fcd1883a72c89c589cc1552b682 263 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 14 262 31.877 T 14-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 LH59_16700 5acf5fcd1883a72c89c589cc1552b682 263 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 12 243 2.4E-61 T 14-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 LH59_16700 5acf5fcd1883a72c89c589cc1552b682 263 SUPERFAMILY SSF51366 1 249 2.17E-78 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 LH59_12100 61e746e6febcf543ed58c2c322204a00 576 Gene3D G3DSA:3.40.190.10 186 507 1.1E-46 T 14-10-2018 LH59_12100 61e746e6febcf543ed58c2c322204a00 576 SUPERFAMILY SSF53850 66 516 2.81E-62 T 14-10-2018 LH59_12100 61e746e6febcf543ed58c2c322204a00 576 PIRSF PIRSF035859 1 575 0.0 T 14-10-2018 IPR014597 ABC transporter, periplasmic substrate-binding protein, predicted GO:0005215 LH59_12100 61e746e6febcf543ed58c2c322204a00 576 Gene3D G3DSA:3.40.190.10 84 464 1.1E-46 T 14-10-2018 LH59_12100 61e746e6febcf543ed58c2c322204a00 576 Pfam PF01547 Bacterial extracellular solute-binding protein 82 424 2.2E-11 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein LH59_01400 bc6037bb823a2c8b937b6c9823a77fc1 229 TIGRFAM TIGR01387 cztR_silR_copR: heavy metal response regulator 3 224 3.7E-91 T 14-10-2018 IPR006291 Transcriptional regulatory protein PcoR, heavy metal response GO:0003677|GO:0006355 LH59_01400 bc6037bb823a2c8b937b6c9823a77fc1 229 Gene3D G3DSA:1.10.10.10 127 229 1.4E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_01400 bc6037bb823a2c8b937b6c9823a77fc1 229 SMART SM00448 1 111 1.1E-42 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_01400 bc6037bb823a2c8b937b6c9823a77fc1 229 SMART SM00862 149 224 6.3E-23 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_01400 bc6037bb823a2c8b937b6c9823a77fc1 229 SUPERFAMILY SSF52172 1 119 8.82E-39 T 14-10-2018 IPR011006 CheY-like superfamily LH59_01400 bc6037bb823a2c8b937b6c9823a77fc1 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 224 1.5E-24 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_01400 bc6037bb823a2c8b937b6c9823a77fc1 229 Gene3D G3DSA:3.40.50.2300 1 125 4.7E-39 T 14-10-2018 LH59_01400 bc6037bb823a2c8b937b6c9823a77fc1 229 Pfam PF00072 Response regulator receiver domain 3 111 2.9E-29 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_01400 bc6037bb823a2c8b937b6c9823a77fc1 229 SUPERFAMILY SSF46894 127 225 7.94E-29 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LH59_07975 a1fef7f7df0a4e67c7fdb53a0af87d01 305 Pfam PF03466 LysR substrate binding domain 88 293 1.7E-36 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_07975 a1fef7f7df0a4e67c7fdb53a0af87d01 305 SUPERFAMILY SSF53850 87 294 2.53E-36 T 14-10-2018 LH59_07975 a1fef7f7df0a4e67c7fdb53a0af87d01 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 3.5E-19 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_07975 a1fef7f7df0a4e67c7fdb53a0af87d01 305 Gene3D G3DSA:1.10.10.10 1 91 5.3E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_07975 a1fef7f7df0a4e67c7fdb53a0af87d01 305 Gene3D G3DSA:3.40.190.10 163 268 1.4E-72 T 14-10-2018 LH59_07975 a1fef7f7df0a4e67c7fdb53a0af87d01 305 SUPERFAMILY SSF46785 1 112 4.0E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_07975 a1fef7f7df0a4e67c7fdb53a0af87d01 305 Gene3D G3DSA:3.40.190.10 92 291 1.4E-72 T 14-10-2018 LH59_07975 a1fef7f7df0a4e67c7fdb53a0af87d01 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.1E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_07975 a1fef7f7df0a4e67c7fdb53a0af87d01 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.1E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_07975 a1fef7f7df0a4e67c7fdb53a0af87d01 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.1E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_06515 d3d58612ef6ad64b90b2544847905d25 409 SMART SM00825 Beta-ketoacyl synthase 5 409 4.4E-15 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain LH59_06515 d3d58612ef6ad64b90b2544847905d25 409 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 3 406 7.3E-197 T 14-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 LH59_06515 d3d58612ef6ad64b90b2544847905d25 409 SUPERFAMILY SSF53901 213 408 9.05E-67 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_06515 d3d58612ef6ad64b90b2544847905d25 409 SUPERFAMILY SSF53901 2 251 8.51E-84 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_06515 d3d58612ef6ad64b90b2544847905d25 409 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 154 170 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site LH59_06515 d3d58612ef6ad64b90b2544847905d25 409 Gene3D G3DSA:3.40.47.10 256 398 5.4E-48 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_06515 d3d58612ef6ad64b90b2544847905d25 409 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 254 366 1.3E-31 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal LH59_06515 d3d58612ef6ad64b90b2544847905d25 409 Gene3D G3DSA:3.40.47.10 1 255 1.7E-98 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_06515 d3d58612ef6ad64b90b2544847905d25 409 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3 246 7.5E-65 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal LH59_06515 d3d58612ef6ad64b90b2544847905d25 409 PIRSF PIRSF000447 1 409 3.5E-183 T 14-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 LH59_04030 e588faa984bb64f3546fc0a20a20784d 389 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 38 389 1.8E-122 T 14-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 LH59_04030 e588faa984bb64f3546fc0a20a20784d 389 ProSitePatterns PS01347 MraY family signature 1. 68 80 - T 14-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 LH59_04030 e588faa984bb64f3546fc0a20a20784d 389 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 25 387 23.553 T 14-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 LH59_04030 e588faa984bb64f3546fc0a20a20784d 389 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 68 80 2.6E-4 T 14-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 LH59_04030 e588faa984bb64f3546fc0a20a20784d 389 ProSitePatterns PS01348 MraY family signature 2. 212 223 - T 14-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 LH59_04030 e588faa984bb64f3546fc0a20a20784d 389 Pfam PF00953 Glycosyl transferase family 4 99 307 2.0E-34 T 14-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 LH59_26900 851333d12e47bac8a614aeaf61b9bb8a 145 Pfam PF04143 Sulphur transport 45 131 8.6E-8 T 14-10-2018 IPR007272 Sulphur transport domain LH59_03590 f820507adf126b14a49e252ddfae3e1f 153 Hamap MF_00042 Ribonuclease H [rnhA]. 8 153 33.639 T 14-10-2018 IPR022892 Ribonuclease HI GO:0004523 LH59_03590 f820507adf126b14a49e252ddfae3e1f 153 Gene3D G3DSA:3.30.420.10 4 152 1.2E-60 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 LH59_03590 f820507adf126b14a49e252ddfae3e1f 153 Pfam PF00075 RNase H 9 147 6.5E-51 T 14-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 LH59_03590 f820507adf126b14a49e252ddfae3e1f 153 SUPERFAMILY SSF53098 10 148 2.15E-57 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily LH59_18830 df7dcdf4b86653bd53a18d7256751555 393 Gene3D G3DSA:3.40.47.10 6 276 4.4E-137 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_18830 df7dcdf4b86653bd53a18d7256751555 393 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 391 8.0E-123 T 14-10-2018 IPR002155 Thiolase GO:0016747 LH59_18830 df7dcdf4b86653bd53a18d7256751555 393 PIRSF PIRSF000429 1 393 2.5E-109 T 14-10-2018 IPR002155 Thiolase GO:0016747 LH59_18830 df7dcdf4b86653bd53a18d7256751555 393 SUPERFAMILY SSF53901 271 392 3.34E-40 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_18830 df7dcdf4b86653bd53a18d7256751555 393 Pfam PF02803 Thiolase, C-terminal domain 271 391 4.9E-42 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 LH59_18830 df7dcdf4b86653bd53a18d7256751555 393 ProSitePatterns PS00099 Thiolases active site. 374 387 - T 14-10-2018 IPR020610 Thiolase, active site GO:0016747 LH59_18830 df7dcdf4b86653bd53a18d7256751555 393 Pfam PF00108 Thiolase, N-terminal domain 5 263 5.3E-83 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 LH59_18830 df7dcdf4b86653bd53a18d7256751555 393 Gene3D G3DSA:3.40.47.10 127 389 4.4E-137 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_18830 df7dcdf4b86653bd53a18d7256751555 393 SUPERFAMILY SSF53901 5 269 2.47E-75 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_21425 7e1aaa46b516404b927afc960a91479b 432 Gene3D G3DSA:3.10.580.10 278 390 4.6E-6 T 14-10-2018 LH59_21425 7e1aaa46b516404b927afc960a91479b 432 SUPERFAMILY SSF54631 276 391 2.56E-10 T 14-10-2018 LH59_21425 7e1aaa46b516404b927afc960a91479b 432 Gene3D G3DSA:3.40.50.300 27 268 1.9E-70 T 14-10-2018 LH59_21425 7e1aaa46b516404b927afc960a91479b 432 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_21425 7e1aaa46b516404b927afc960a91479b 432 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 37 388 4.6E-123 T 14-10-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 LH59_21425 7e1aaa46b516404b927afc960a91479b 432 SUPERFAMILY SSF52540 42 270 1.11E-74 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_21425 7e1aaa46b516404b927afc960a91479b 432 SMART SM00382 52 240 3.1E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_21425 7e1aaa46b516404b927afc960a91479b 432 Pfam PF00005 ABC transporter 43 191 8.1E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_21455 5c347666adaa320926924d16adf9e44f 55 Pfam PF00471 Ribosomal protein L33 7 53 1.7E-17 T 14-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_21455 5c347666adaa320926924d16adf9e44f 55 SUPERFAMILY SSF57829 1 53 2.81E-19 T 14-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 LH59_21455 5c347666adaa320926924d16adf9e44f 55 Gene3D G3DSA:2.20.28.120 1 55 3.7E-29 T 14-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_21455 5c347666adaa320926924d16adf9e44f 55 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 55 1.7E-25 T 14-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_21455 5c347666adaa320926924d16adf9e44f 55 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 5 53 14.773 T 14-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_18255 5bee27fe712ff876e949ac4839c3fe3c 686 Pfam PF07715 TonB-dependent Receptor Plug Domain 40 137 7.3E-11 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_18255 5bee27fe712ff876e949ac4839c3fe3c 686 SUPERFAMILY SSF56935 8 685 4.28E-125 T 14-10-2018 LH59_18255 5bee27fe712ff876e949ac4839c3fe3c 686 Pfam PF00593 TonB dependent receptor 255 684 7.1E-60 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_18255 5bee27fe712ff876e949ac4839c3fe3c 686 Gene3D G3DSA:2.170.130.10 19 146 3.4E-33 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily LH59_18255 5bee27fe712ff876e949ac4839c3fe3c 686 Gene3D G3DSA:2.40.170.20 147 686 3.1E-179 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_18255 5bee27fe712ff876e949ac4839c3fe3c 686 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 42 684 5.2E-127 T 14-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 LH59_19505 ec341e27df9f0e9e220b3a5097b4a9c5 218 Gene3D G3DSA:2.60.120.10 1 140 4.4E-24 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_19505 ec341e27df9f0e9e220b3a5097b4a9c5 218 SUPERFAMILY SSF51206 1 138 5.24E-23 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like LH59_19505 ec341e27df9f0e9e220b3a5097b4a9c5 218 Pfam PF00027 Cyclic nucleotide-binding domain 25 112 5.9E-12 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain LH59_19505 ec341e27df9f0e9e220b3a5097b4a9c5 218 Pfam PF13545 Crp-like helix-turn-helix domain 145 214 6.2E-15 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 LH59_19505 ec341e27df9f0e9e220b3a5097b4a9c5 218 SMART SM00100 6 125 3.9E-9 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain LH59_19505 ec341e27df9f0e9e220b3a5097b4a9c5 218 SUPERFAMILY SSF46785 143 217 5.22E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_19505 ec341e27df9f0e9e220b3a5097b4a9c5 218 SMART SM00419 159 207 1.9E-9 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 LH59_19505 ec341e27df9f0e9e220b3a5097b4a9c5 218 Gene3D G3DSA:1.10.10.10 141 216 9.2E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_19505 ec341e27df9f0e9e220b3a5097b4a9c5 218 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 181 196 6.5E-6 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 LH59_19505 ec341e27df9f0e9e220b3a5097b4a9c5 218 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 165 181 6.5E-6 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 LH59_06015 4e99acd2ede645761e96457648fceafe 376 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 57 268 2.0E-34 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain LH59_06015 4e99acd2ede645761e96457648fceafe 376 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 44 357 4.7E-75 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 LH59_06015 4e99acd2ede645761e96457648fceafe 376 Gene3D G3DSA:1.10.287.470 102 161 1.1E-72 T 14-10-2018 LH59_06015 4e99acd2ede645761e96457648fceafe 376 Gene3D G3DSA:2.40.30.170 60 278 1.1E-72 T 14-10-2018 LH59_06015 4e99acd2ede645761e96457648fceafe 376 Gene3D G3DSA:2.40.50.100 67 195 1.1E-72 T 14-10-2018 LH59_06015 4e99acd2ede645761e96457648fceafe 376 SUPERFAMILY SSF111369 61 272 2.75E-42 T 14-10-2018 LH59_06015 4e99acd2ede645761e96457648fceafe 376 Gene3D G3DSA:2.40.420.20 279 355 1.1E-72 T 14-10-2018 LH59_24535 d0890b6e02e2de2b00f2929b14a49958 204 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 4 172 2.7E-36 T 14-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 LH59_24535 d0890b6e02e2de2b00f2929b14a49958 204 Gene3D G3DSA:2.40.240.10 1 94 3.3E-30 T 14-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 LH59_24535 d0890b6e02e2de2b00f2929b14a49958 204 Pfam PF01386 Ribosomal L25p family 4 91 1.9E-23 T 14-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 LH59_24535 d0890b6e02e2de2b00f2929b14a49958 204 Gene3D G3DSA:2.170.120.20 96 190 1.1E-19 T 14-10-2018 IPR037121 Ribosomal protein L25, C-terminal LH59_24535 d0890b6e02e2de2b00f2929b14a49958 204 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 1 94 1.0E-36 T 14-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 LH59_24535 d0890b6e02e2de2b00f2929b14a49958 204 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 1 185 29.272 T 14-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 LH59_24535 d0890b6e02e2de2b00f2929b14a49958 204 Hamap MF_01336 50S ribosomal protein L25 [rplY]. 1 94 23.085 T 14-10-2018 IPR020055 Ribosomal protein L25, short-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 LH59_24535 d0890b6e02e2de2b00f2929b14a49958 204 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 100 174 2.2E-22 T 14-10-2018 IPR020057 Ribosomal protein L25, beta domain LH59_24535 d0890b6e02e2de2b00f2929b14a49958 204 SUPERFAMILY SSF50715 1 190 1.1E-49 T 14-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 LH59_13590 c4a590d5507972c0d67eaaf8a9d9324d 382 Pfam PF15887 Putative zinc-binding metallo-peptidase 129 376 3.5E-102 T 14-10-2018 IPR031321 Uncharacterised conserved protein UCP012641, putative zinc-binding metallo-peptidase LH59_13590 c4a590d5507972c0d67eaaf8a9d9324d 382 PIRSF PIRSF012641 27 382 5.3E-127 T 14-10-2018 IPR031321 Uncharacterised conserved protein UCP012641, putative zinc-binding metallo-peptidase LH59_13590 c4a590d5507972c0d67eaaf8a9d9324d 382 Pfam PF10005 zinc-ribbon domain 30 122 3.1E-27 T 14-10-2018 IPR011201 Zinc-ribbon domain, bacteria LH59_05020 46bd1ca7ae10a457e87a8826e95c9acc 190 Pfam PF01330 RuvA N terminal domain 1 62 1.6E-20 T 14-10-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 LH59_05020 46bd1ca7ae10a457e87a8826e95c9acc 190 SMART SM00278 73 92 3.5 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 LH59_05020 46bd1ca7ae10a457e87a8826e95c9acc 190 SMART SM00278 108 127 0.0015 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 LH59_05020 46bd1ca7ae10a457e87a8826e95c9acc 190 SUPERFAMILY SSF46929 145 189 5.23E-8 T 14-10-2018 IPR036267 RuvA, C-terminal domain superfamily LH59_05020 46bd1ca7ae10a457e87a8826e95c9acc 190 SUPERFAMILY SSF50249 1 63 2.28E-18 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_05020 46bd1ca7ae10a457e87a8826e95c9acc 190 Pfam PF14520 Helix-hairpin-helix domain 72 129 1.5E-17 T 14-10-2018 LH59_05020 46bd1ca7ae10a457e87a8826e95c9acc 190 Gene3D G3DSA:1.10.8.10 144 188 3.4E-5 T 14-10-2018 LH59_05020 46bd1ca7ae10a457e87a8826e95c9acc 190 Gene3D G3DSA:1.10.150.20 67 138 1.9E-24 T 14-10-2018 LH59_05020 46bd1ca7ae10a457e87a8826e95c9acc 190 Pfam PF07499 RuvA, C-terminal domain 146 188 1.2E-11 T 14-10-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 LH59_05020 46bd1ca7ae10a457e87a8826e95c9acc 190 SUPERFAMILY SSF47781 67 133 3.2E-19 T 14-10-2018 IPR010994 RuvA domain 2-like LH59_05020 46bd1ca7ae10a457e87a8826e95c9acc 190 Gene3D G3DSA:2.40.50.140 1 65 3.0E-26 T 14-10-2018 LH59_05020 46bd1ca7ae10a457e87a8826e95c9acc 190 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 189 30.093 T 14-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 LH59_05020 46bd1ca7ae10a457e87a8826e95c9acc 190 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 188 1.4E-50 T 14-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 LH59_14640 a2357c0fd5f7c30ef7fbdef7d3c21673 429 ProSitePatterns PS00318 Hydroxymethylglutaryl-coenzyme A reductases signature 2. 325 332 - T 14-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 LH59_14640 a2357c0fd5f7c30ef7fbdef7d3c21673 429 ProSitePatterns PS00066 Hydroxymethylglutaryl-coenzyme A reductases signature 1. 176 190 - T 14-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 LH59_14640 a2357c0fd5f7c30ef7fbdef7d3c21673 429 Pfam PF00368 Hydroxymethylglutaryl-coenzyme A reductase 16 386 1.3E-113 T 14-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 LH59_14640 a2357c0fd5f7c30ef7fbdef7d3c21673 429 ProSitePatterns PS01192 Hydroxymethylglutaryl-coenzyme A reductases signature 3. 371 384 - T 14-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 LH59_14640 a2357c0fd5f7c30ef7fbdef7d3c21673 429 TIGRFAM TIGR00532 HMG_CoA_R_NAD: hydroxymethylglutaryl-CoA reductase, degradative 4 386 3.1E-126 T 14-10-2018 IPR004553 Hydroxymethylglutaryl-CoA reductase, bacterial-type GO:0015936|GO:0016616|GO:0050662 LH59_14640 a2357c0fd5f7c30ef7fbdef7d3c21673 429 Gene3D G3DSA:3.30.70.420 110 220 2.5E-137 T 14-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 LH59_14640 a2357c0fd5f7c30ef7fbdef7d3c21673 429 SUPERFAMILY SSF55035 111 219 1.91E-31 T 14-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 LH59_14640 a2357c0fd5f7c30ef7fbdef7d3c21673 429 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 50 71 3.5E-8 T 14-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 LH59_14640 a2357c0fd5f7c30ef7fbdef7d3c21673 429 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 77 97 3.5E-8 T 14-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 LH59_14640 a2357c0fd5f7c30ef7fbdef7d3c21673 429 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 313 334 3.5E-8 T 14-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 LH59_14640 a2357c0fd5f7c30ef7fbdef7d3c21673 429 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 174 192 3.5E-8 T 14-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 LH59_14640 a2357c0fd5f7c30ef7fbdef7d3c21673 429 Gene3D G3DSA:3.90.770.10 16 372 2.5E-137 T 14-10-2018 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamily GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 LH59_14640 a2357c0fd5f7c30ef7fbdef7d3c21673 429 Gene3D G3DSA:1.10.8.660 376 427 1.0E-15 T 14-10-2018 LH59_14640 a2357c0fd5f7c30ef7fbdef7d3c21673 429 SUPERFAMILY SSF56542 7 427 6.67E-105 T 14-10-2018 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 LH59_01355 5cea255665fac927891fb5538c5cbedf 305 SUPERFAMILY SSF46785 8 94 5.9E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_01355 5cea255665fac927891fb5538c5cbedf 305 SUPERFAMILY SSF53850 113 297 5.43E-25 T 14-10-2018 LH59_01355 5cea255665fac927891fb5538c5cbedf 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 69 4.0E-14 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_01355 5cea255665fac927891fb5538c5cbedf 305 Gene3D G3DSA:1.10.10.10 8 97 5.0E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_01355 5cea255665fac927891fb5538c5cbedf 305 Gene3D G3DSA:3.40.190.290 98 299 2.4E-18 T 14-10-2018 LH59_01355 5cea255665fac927891fb5538c5cbedf 305 Pfam PF03466 LysR substrate binding domain 98 297 2.2E-23 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_22345 b7a49d52c8059de4fce4e91597e0116a 151 SUPERFAMILY SSF51316 14 148 2.09E-40 T 14-10-2018 IPR011057 Mss4-like superfamily LH59_22345 b7a49d52c8059de4fce4e91597e0116a 151 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 40 129 3.6E-23 T 14-10-2018 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 LH59_22345 b7a49d52c8059de4fce4e91597e0116a 151 Gene3D G3DSA:3.90.1590.10 2 130 4.3E-14 T 14-10-2018 LH59_20580 1fb5f6253826aa825021e23ba5ae49c5 866 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 690 706 - T 14-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 LH59_20580 1fb5f6253826aa825021e23ba5ae49c5 866 Gene3D G3DSA:3.40.50.300 571 863 1.2E-92 T 14-10-2018 LH59_20580 1fb5f6253826aa825021e23ba5ae49c5 866 Pfam PF05188 MutS domain II 122 245 2.7E-17 T 14-10-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 LH59_20580 1fb5f6253826aa825021e23ba5ae49c5 866 Pfam PF00488 MutS domain V 613 799 3.5E-80 T 14-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 LH59_20580 1fb5f6253826aa825021e23ba5ae49c5 866 Gene3D G3DSA:3.30.420.110 120 252 4.1E-31 T 14-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 LH59_20580 1fb5f6253826aa825021e23ba5ae49c5 866 Gene3D G3DSA:3.40.1170.10 1 112 5.8E-45 T 14-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 LH59_20580 1fb5f6253826aa825021e23ba5ae49c5 866 Pfam PF05190 MutS family domain IV 431 522 9.2E-30 T 14-10-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 LH59_20580 1fb5f6253826aa825021e23ba5ae49c5 866 SUPERFAMILY SSF52540 570 799 3.62E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_20580 1fb5f6253826aa825021e23ba5ae49c5 866 SUPERFAMILY SSF48334 259 568 3.01E-85 T 14-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily LH59_20580 1fb5f6253826aa825021e23ba5ae49c5 866 SUPERFAMILY SSF55271 1 106 1.7E-37 T 14-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 LH59_20580 1fb5f6253826aa825021e23ba5ae49c5 866 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 1 863 0.0 T 14-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 LH59_20580 1fb5f6253826aa825021e23ba5ae49c5 866 SMART SM00533 275 594 2.6E-90 T 14-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 LH59_20580 1fb5f6253826aa825021e23ba5ae49c5 866 Pfam PF01624 MutS domain I 1 110 2.8E-38 T 14-10-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 LH59_20580 1fb5f6253826aa825021e23ba5ae49c5 866 SUPERFAMILY SSF53150 108 272 6.54E-36 T 14-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 LH59_20580 1fb5f6253826aa825021e23ba5ae49c5 866 PIRSF PIRSF037677 1 175 1.6E-19 T 14-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 LH59_20580 1fb5f6253826aa825021e23ba5ae49c5 866 PIRSF PIRSF037677 204 841 6.2E-114 T 14-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 LH59_20580 1fb5f6253826aa825021e23ba5ae49c5 866 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 1 857 24.231 T 14-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 LH59_20580 1fb5f6253826aa825021e23ba5ae49c5 866 Pfam PF05192 MutS domain III 262 562 4.2E-35 T 14-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 LH59_20580 1fb5f6253826aa825021e23ba5ae49c5 866 SMART SM00534 609 796 1.8E-105 T 14-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 LH59_20580 1fb5f6253826aa825021e23ba5ae49c5 866 Gene3D G3DSA:1.10.1420.10 258 562 5.0E-96 T 14-10-2018 LH59_20580 1fb5f6253826aa825021e23ba5ae49c5 866 Gene3D G3DSA:1.10.1420.10 389 506 5.0E-96 T 14-10-2018 LH59_11035 57a22a91dd3f8ad7d958c8b8ccebd26a 401 Pfam PF00482 Type II secretion system (T2SS), protein F 68 190 3.0E-32 T 14-10-2018 IPR018076 Type II secretion system F domain LH59_11035 57a22a91dd3f8ad7d958c8b8ccebd26a 401 Pfam PF00482 Type II secretion system (T2SS), protein F 270 392 1.4E-26 T 14-10-2018 IPR018076 Type II secretion system F domain LH59_11035 57a22a91dd3f8ad7d958c8b8ccebd26a 401 Gene3D G3DSA:1.20.81.30 51 169 5.4E-29 T 14-10-2018 LH59_11035 57a22a91dd3f8ad7d958c8b8ccebd26a 401 Gene3D G3DSA:1.20.81.30 253 365 6.7E-24 T 14-10-2018 LH59_11035 57a22a91dd3f8ad7d958c8b8ccebd26a 401 TIGRFAM TIGR02120 GspF: type II secretion system protein F 4 400 1.1E-156 T 14-10-2018 IPR011850 General secretion pathway protein F GO:0008565|GO:0015627|GO:0015628 LH59_11035 57a22a91dd3f8ad7d958c8b8ccebd26a 401 PRINTS PR00812 Bacterial general secretion pathway protein F signature 162 190 4.5E-28 T 14-10-2018 IPR003004 GspF/PilC family LH59_11035 57a22a91dd3f8ad7d958c8b8ccebd26a 401 PRINTS PR00812 Bacterial general secretion pathway protein F signature 365 379 4.5E-28 T 14-10-2018 IPR003004 GspF/PilC family LH59_11035 57a22a91dd3f8ad7d958c8b8ccebd26a 401 PRINTS PR00812 Bacterial general secretion pathway protein F signature 63 75 4.5E-28 T 14-10-2018 IPR003004 GspF/PilC family LH59_11035 57a22a91dd3f8ad7d958c8b8ccebd26a 401 PRINTS PR00812 Bacterial general secretion pathway protein F signature 381 400 4.5E-28 T 14-10-2018 IPR003004 GspF/PilC family LH59_03420 53a88147888dc2b6e9953e7064b1a82a 159 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 154 84.511 T 14-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 LH59_03420 53a88147888dc2b6e9953e7064b1a82a 159 Pfam PF03477 ATP cone domain 50 136 2.9E-14 T 14-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 LH59_03420 53a88147888dc2b6e9953e7064b1a82a 159 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 146 3.1E-59 T 14-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 LH59_24090 ce479678cbea2734359f6a11b6b6db62 325 Gene3D G3DSA:2.60.120.1440 115 238 3.1E-17 T 14-10-2018 LH59_24090 ce479678cbea2734359f6a11b6b6db62 325 Pfam PF04773 FecR protein 121 213 2.6E-21 T 14-10-2018 IPR006860 FecR protein LH59_24090 ce479678cbea2734359f6a11b6b6db62 325 Pfam PF16220 Domain of unknown function (DUF4880) 14 56 1.5E-11 T 14-10-2018 IPR032623 FecR, N-terminal LH59_24090 ce479678cbea2734359f6a11b6b6db62 325 PIRSF PIRSF018266 3 325 6.4E-81 T 14-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component LH59_06365 7e4eee7bcd659ec5e35acb9b48474fa4 213 Gene3D G3DSA:3.20.20.20 7 70 3.1E-14 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LH59_06365 7e4eee7bcd659ec5e35acb9b48474fa4 213 Pfam PF14697 4Fe-4S dicluster domain 79 133 1.1E-17 T 14-10-2018 LH59_06365 7e4eee7bcd659ec5e35acb9b48474fa4 213 Gene3D G3DSA:3.30.70.20 71 150 3.2E-20 T 14-10-2018 LH59_06365 7e4eee7bcd659ec5e35acb9b48474fa4 213 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 116 127 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site LH59_06365 7e4eee7bcd659ec5e35acb9b48474fa4 213 SUPERFAMILY SSF54862 8 135 4.95E-28 T 14-10-2018 LH59_06365 7e4eee7bcd659ec5e35acb9b48474fa4 213 Pfam PF04060 Putative Fe-S cluster 14 46 1.2E-13 T 14-10-2018 IPR007202 4Fe-4S domain GO:0051536 LH59_06365 7e4eee7bcd659ec5e35acb9b48474fa4 213 TIGRFAM TIGR01944 rnfB: electron transport complex, RnfABCDGE type, B subunit 4 142 6.8E-64 T 14-10-2018 IPR010207 Ion-translocating oxidoreductase complex, RnfB/RsxB GO:0009055|GO:0051536 LH59_21550 4647648fa813e3a8036b780576701ded 288 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 3.1E-14 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_21550 4647648fa813e3a8036b780576701ded 288 SUPERFAMILY SSF53850 89 287 4.71E-40 T 14-10-2018 LH59_21550 4647648fa813e3a8036b780576701ded 288 SUPERFAMILY SSF46785 1 111 5.9E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_21550 4647648fa813e3a8036b780576701ded 288 Gene3D G3DSA:3.40.190.290 90 285 5.2E-35 T 14-10-2018 LH59_21550 4647648fa813e3a8036b780576701ded 288 Gene3D G3DSA:1.10.10.10 1 87 4.9E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_21550 4647648fa813e3a8036b780576701ded 288 Pfam PF03466 LysR substrate binding domain 88 285 1.0E-36 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_05170 964c26486e0cca3c34b78dcf3b3e68b5 325 PIRSF PIRSF017082 1 325 3.8E-79 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_05170 964c26486e0cca3c34b78dcf3b3e68b5 325 Gene3D G3DSA:3.40.190.10 125 248 1.3E-111 T 14-10-2018 LH59_05170 964c26486e0cca3c34b78dcf3b3e68b5 325 SUPERFAMILY SSF53850 113 287 2.39E-11 T 14-10-2018 LH59_05170 964c26486e0cca3c34b78dcf3b3e68b5 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 321 7.7E-80 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_05170 964c26486e0cca3c34b78dcf3b3e68b5 325 Gene3D G3DSA:3.40.190.150 27 319 1.3E-111 T 14-10-2018 LH59_19400 772c8a90b534bc06dc9118aa19d4c6f0 703 SUPERFAMILY SSF81296 12 158 1.85E-43 T 14-10-2018 IPR014756 Immunoglobulin E-set LH59_19400 772c8a90b534bc06dc9118aa19d4c6f0 703 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 12 694 2.1E-299 T 14-10-2018 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 LH59_19400 772c8a90b534bc06dc9118aa19d4c6f0 703 SUPERFAMILY SSF51445 149 584 1.77E-122 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily LH59_19400 772c8a90b534bc06dc9118aa19d4c6f0 703 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 16 104 1.0E-14 T 14-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 LH59_19400 772c8a90b534bc06dc9118aa19d4c6f0 703 SMART SM00642 193 577 9.6E-7 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 LH59_19400 772c8a90b534bc06dc9118aa19d4c6f0 703 Gene3D G3DSA:3.20.20.80 150 591 4.5E-160 T 14-10-2018 LH59_19400 772c8a90b534bc06dc9118aa19d4c6f0 703 Pfam PF00128 Alpha amylase, catalytic domain 201 351 2.7E-7 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 LH59_19400 772c8a90b534bc06dc9118aa19d4c6f0 703 Gene3D G3DSA:2.60.40.10 4 146 4.1E-48 T 14-10-2018 IPR013783 Immunoglobulin-like fold LH59_19400 772c8a90b534bc06dc9118aa19d4c6f0 703 SUPERFAMILY SSF51011 598 695 1.01E-13 T 14-10-2018 LH59_19400 772c8a90b534bc06dc9118aa19d4c6f0 703 Gene3D G3DSA:2.60.40.1180 598 695 9.6E-9 T 14-10-2018 IPR013780 Glycosyl hydrolase, all-beta LH59_01010 d86b173cea9cec34483919cc639bb9c7 262 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 19 260 2.4E-82 T 14-10-2018 IPR003453 ABC transport permease subunit MlaE, Proteobacteria LH59_01010 d86b173cea9cec34483919cc639bb9c7 262 Pfam PF02405 Permease MlaE 47 258 7.4E-75 T 14-10-2018 IPR030802 ABC transporter permease MalE GO:0043190 LH59_12745 3b275c1a27c63e50cbd282d2d229fd6d 354 SMART SM00091 1 66 1.3E-4 T 14-10-2018 IPR000014 PAS domain LH59_12745 3b275c1a27c63e50cbd282d2d229fd6d 354 SUPERFAMILY SSF47384 110 182 9.02E-13 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 LH59_12745 3b275c1a27c63e50cbd282d2d229fd6d 354 PRINTS PR00344 Bacterial sensor protein C-terminal signature 302 312 7.5E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_12745 3b275c1a27c63e50cbd282d2d229fd6d 354 PRINTS PR00344 Bacterial sensor protein C-terminal signature 313 331 7.5E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_12745 3b275c1a27c63e50cbd282d2d229fd6d 354 PRINTS PR00344 Bacterial sensor protein C-terminal signature 336 349 7.5E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_12745 3b275c1a27c63e50cbd282d2d229fd6d 354 PRINTS PR00344 Bacterial sensor protein C-terminal signature 284 298 7.5E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_12745 3b275c1a27c63e50cbd282d2d229fd6d 354 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 229 351 1.6E-16 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_12745 3b275c1a27c63e50cbd282d2d229fd6d 354 Pfam PF00512 His Kinase A (phospho-acceptor) domain 125 180 3.4E-13 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_12745 3b275c1a27c63e50cbd282d2d229fd6d 354 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 11 109 3.0E-7 T 14-10-2018 IPR000014 PAS domain LH59_12745 3b275c1a27c63e50cbd282d2d229fd6d 354 SMART SM00387 229 352 5.7E-27 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_12745 3b275c1a27c63e50cbd282d2d229fd6d 354 Pfam PF08448 PAS fold 11 108 7.1E-8 T 14-10-2018 IPR013656 PAS fold-4 LH59_12745 3b275c1a27c63e50cbd282d2d229fd6d 354 SMART SM00388 124 189 3.4E-13 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_12745 3b275c1a27c63e50cbd282d2d229fd6d 354 Gene3D G3DSA:1.10.287.130 128 185 3.5E-11 T 14-10-2018 LH59_12745 3b275c1a27c63e50cbd282d2d229fd6d 354 Gene3D G3DSA:3.30.450.20 2 107 7.7E-11 T 14-10-2018 LH59_12745 3b275c1a27c63e50cbd282d2d229fd6d 354 SUPERFAMILY SSF55785 6 68 5.76E-8 T 14-10-2018 IPR035965 PAS domain superfamily LH59_12745 3b275c1a27c63e50cbd282d2d229fd6d 354 Gene3D G3DSA:3.30.565.10 188 350 5.0E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_12745 3b275c1a27c63e50cbd282d2d229fd6d 354 SUPERFAMILY SSF55874 191 350 2.88E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_02910 f149410c5a3c1299ee3d9b8a6dc7dc9b 653 Gene3D G3DSA:1.20.1480.50 305 386 7.9E-13 T 14-10-2018 LH59_02910 f149410c5a3c1299ee3d9b8a6dc7dc9b 653 SMART SM00304 327 379 1.6E-16 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_02910 f149410c5a3c1299ee3d9b8a6dc7dc9b 653 Pfam PF00672 HAMP domain 327 375 2.3E-14 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_02910 f149410c5a3c1299ee3d9b8a6dc7dc9b 653 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 456 652 1.0E-22 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 LH59_02910 f149410c5a3c1299ee3d9b8a6dc7dc9b 653 Gene3D G3DSA:3.60.40.10 394 651 2.2E-50 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 LH59_02910 f149410c5a3c1299ee3d9b8a6dc7dc9b 653 SUPERFAMILY SSF158472 327 376 2.62E-11 T 14-10-2018 LH59_02910 f149410c5a3c1299ee3d9b8a6dc7dc9b 653 SMART SM00331 429 652 2.2E-4 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 LH59_28120 bfb7f3971665f64337b1ea7abb3a9512 229 SUPERFAMILY SSF53335 20 224 1.34E-31 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_28120 bfb7f3971665f64337b1ea7abb3a9512 229 Gene3D G3DSA:3.40.50.150 2 229 1.7E-60 T 14-10-2018 LH59_28120 bfb7f3971665f64337b1ea7abb3a9512 229 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 36 222 3.0E-42 T 14-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 LH59_28120 bfb7f3971665f64337b1ea7abb3a9512 229 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 24 221 24.393 T 14-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 LH59_28120 bfb7f3971665f64337b1ea7abb3a9512 229 Pfam PF02527 rRNA small subunit methyltransferase G 33 217 1.1E-44 T 14-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 LH59_28120 bfb7f3971665f64337b1ea7abb3a9512 229 PIRSF PIRSF003078 9 226 2.2E-49 T 14-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 LH59_06815 ea0ef5aea3d34712092e69f9c707288c 309 Hamap MF_00117 33 kDa chaperonin [hslO]. 2 297 29.101 T 14-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 LH59_06815 ea0ef5aea3d34712092e69f9c707288c 309 PIRSF PIRSF005261 1 297 1.1E-73 T 14-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 LH59_06815 ea0ef5aea3d34712092e69f9c707288c 309 Gene3D G3DSA:1.10.287.480 190 238 3.5E-10 T 14-10-2018 IPR023212 Heat shock protein Hsp33, helix hairpin bin domain superfamily LH59_06815 ea0ef5aea3d34712092e69f9c707288c 309 Pfam PF01430 Hsp33 protein 3 286 3.5E-83 T 14-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 LH59_06815 ea0ef5aea3d34712092e69f9c707288c 309 SUPERFAMILY SSF118352 238 295 2.09E-19 T 14-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 LH59_06815 ea0ef5aea3d34712092e69f9c707288c 309 Gene3D G3DSA:3.90.1280.10 239 297 6.6E-22 T 14-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 LH59_06815 ea0ef5aea3d34712092e69f9c707288c 309 Gene3D G3DSA:3.55.30.10 1 179 5.6E-60 T 14-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 LH59_06815 ea0ef5aea3d34712092e69f9c707288c 309 SUPERFAMILY SSF64397 3 245 6.67E-62 T 14-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 LH59_23155 e3f45a1d9d0bf0f21051ace51d0f0ce6 166 Gene3D G3DSA:1.10.10.10 71 156 1.3E-34 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_23155 e3f45a1d9d0bf0f21051ace51d0f0ce6 166 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 6 152 36.517 T 14-10-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 LH59_23155 e3f45a1d9d0bf0f21051ace51d0f0ce6 166 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 73 152 2.4E-32 T 14-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 LH59_23155 e3f45a1d9d0bf0f21051ace51d0f0ce6 166 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 122 128 - T 14-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 LH59_23155 e3f45a1d9d0bf0f21051ace51d0f0ce6 166 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 72 151 4.6E-35 T 14-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 LH59_23155 e3f45a1d9d0bf0f21051ace51d0f0ce6 166 SUPERFAMILY SSF46767 71 153 1.14E-31 T 14-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 LH59_11570 f0e5b3e92b6377f958143781be870cd0 125 SUPERFAMILY SSF160214 35 121 4.32E-23 T 14-10-2018 IPR035924 FlaG-like superfamily LH59_11570 f0e5b3e92b6377f958143781be870cd0 125 Gene3D G3DSA:3.30.160.170 30 119 6.0E-15 T 14-10-2018 IPR035924 FlaG-like superfamily LH59_11570 f0e5b3e92b6377f958143781be870cd0 125 Pfam PF03646 FlaG protein 35 119 3.6E-23 T 14-10-2018 IPR005186 FlaG protein LH59_09955 501a69911ba3afca50b6bff7a145a216 360 SUPERFAMILY SSF56672 3 237 2.31E-99 T 14-10-2018 LH59_09955 501a69911ba3afca50b6bff7a145a216 360 Pfam PF11798 IMS family HHH motif 169 200 7.7E-10 T 14-10-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 LH59_09955 501a69911ba3afca50b6bff7a145a216 360 Gene3D G3DSA:3.30.70.270 74 115 5.8E-10 T 14-10-2018 LH59_09955 501a69911ba3afca50b6bff7a145a216 360 SUPERFAMILY SSF100879 243 342 1.39E-19 T 14-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 LH59_09955 501a69911ba3afca50b6bff7a145a216 360 Pfam PF00817 impB/mucB/samB family 11 157 1.1E-51 T 14-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 LH59_09955 501a69911ba3afca50b6bff7a145a216 360 Hamap MF_01113 DNA polymerase IV [dinB]. 5 355 37.727 T 14-10-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 LH59_09955 501a69911ba3afca50b6bff7a145a216 360 Pfam PF11799 impB/mucB/samB family C-terminal domain 237 350 2.2E-17 T 14-10-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 LH59_09955 501a69911ba3afca50b6bff7a145a216 360 Gene3D G3DSA:3.30.1490.100 244 352 4.9E-18 T 14-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 LH59_09955 501a69911ba3afca50b6bff7a145a216 360 Gene3D G3DSA:1.10.150.20 176 239 1.6E-18 T 14-10-2018 LH59_09955 501a69911ba3afca50b6bff7a145a216 360 Gene3D G3DSA:3.30.70.270 116 175 9.7E-25 T 14-10-2018 LH59_09955 501a69911ba3afca50b6bff7a145a216 360 Gene3D G3DSA:2.30.40.20 15 73 2.0E-28 T 14-10-2018 LH59_14195 308e6a4df30f14ade95c2d9ad6053528 298 Gene3D G3DSA:3.40.190.10 94 277 5.0E-38 T 14-10-2018 LH59_14195 308e6a4df30f14ade95c2d9ad6053528 298 Pfam PF03466 LysR substrate binding domain 90 288 1.2E-38 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_14195 308e6a4df30f14ade95c2d9ad6053528 298 Gene3D G3DSA:3.40.190.10 168 267 5.0E-38 T 14-10-2018 LH59_14195 308e6a4df30f14ade95c2d9ad6053528 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 2.5E-19 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_14195 308e6a4df30f14ade95c2d9ad6053528 298 SUPERFAMILY SSF46785 4 113 1.78E-25 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_14195 308e6a4df30f14ade95c2d9ad6053528 298 Gene3D G3DSA:1.10.10.10 3 92 8.4E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_14195 308e6a4df30f14ade95c2d9ad6053528 298 SUPERFAMILY SSF53850 90 288 1.36E-36 T 14-10-2018 LH59_26710 84c4c6774e8c7f0a3ab1d11bea1d2d1c 262 PIRSF PIRSF002854 2 262 2.6E-110 T 14-10-2018 IPR004872 Lipoprotein NlpA family LH59_26710 84c4c6774e8c7f0a3ab1d11bea1d2d1c 262 TIGRFAM TIGR00363 TIGR00363: lipoprotein, YaeC family 21 261 1.0E-78 T 14-10-2018 IPR004872 Lipoprotein NlpA family LH59_26710 84c4c6774e8c7f0a3ab1d11bea1d2d1c 262 Gene3D G3DSA:3.40.190.10 108 212 3.2E-106 T 14-10-2018 LH59_26710 84c4c6774e8c7f0a3ab1d11bea1d2d1c 262 Gene3D G3DSA:3.40.190.10 29 260 3.2E-106 T 14-10-2018 LH59_26710 84c4c6774e8c7f0a3ab1d11bea1d2d1c 262 Pfam PF03180 NLPA lipoprotein 27 262 4.5E-103 T 14-10-2018 IPR004872 Lipoprotein NlpA family LH59_26710 84c4c6774e8c7f0a3ab1d11bea1d2d1c 262 SUPERFAMILY SSF53850 26 262 2.01E-90 T 14-10-2018 LH59_27900 ca9a02868754c54e11a3c32af932a6a3 98 SUPERFAMILY SSF54189 2 92 3.31E-30 T 14-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_27900 ca9a02868754c54e11a3c32af932a6a3 98 Pfam PF00276 Ribosomal protein L23 8 94 1.8E-30 T 14-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 LH59_27900 ca9a02868754c54e11a3c32af932a6a3 98 Gene3D G3DSA:3.30.70.330 1 97 7.5E-33 T 14-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily LH59_27900 ca9a02868754c54e11a3c32af932a6a3 98 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 7 97 22.008 T 14-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 LH59_21580 ecbf6c380efc9ce537a330cad169c69b 295 Pfam PF03466 LysR substrate binding domain 92 280 3.8E-26 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_21580 ecbf6c380efc9ce537a330cad169c69b 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 65 2.2E-19 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_21580 ecbf6c380efc9ce537a330cad169c69b 295 Gene3D G3DSA:1.10.10.10 1 86 1.4E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_21580 ecbf6c380efc9ce537a330cad169c69b 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 2.8E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_21580 ecbf6c380efc9ce537a330cad169c69b 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 2.8E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_21580 ecbf6c380efc9ce537a330cad169c69b 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 2.8E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_21580 ecbf6c380efc9ce537a330cad169c69b 295 Gene3D G3DSA:3.40.190.10 162 254 2.6E-48 T 14-10-2018 LH59_21580 ecbf6c380efc9ce537a330cad169c69b 295 SUPERFAMILY SSF46785 1 111 4.76E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_21580 ecbf6c380efc9ce537a330cad169c69b 295 SUPERFAMILY SSF53850 91 284 1.81E-24 T 14-10-2018 LH59_21580 ecbf6c380efc9ce537a330cad169c69b 295 Gene3D G3DSA:3.40.190.10 96 259 2.6E-48 T 14-10-2018 LH59_23595 102bf053a4c8bc055405d663097eb9cc 163 Gene3D G3DSA:3.10.450.160 60 163 7.6E-38 T 14-10-2018 LH59_23595 102bf053a4c8bc055405d663097eb9cc 163 Pfam PF11776 Nickel/cobalt transporter regulator 128 156 1.0E-5 T 14-10-2018 IPR024572 Nickel/cobalt homeostasis protein RcnB LH59_25790 f09ff676aca0c3060da2bec4680fa856 176 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 4 173 17.375 T 14-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 LH59_25790 f09ff676aca0c3060da2bec4680fa856 176 Gene3D G3DSA:3.90.1140.10 2 172 6.2E-42 T 14-10-2018 LH59_25790 f09ff676aca0c3060da2bec4680fa856 176 SUPERFAMILY SSF55144 5 170 8.89E-36 T 14-10-2018 IPR009097 Cyclic phosphodiesterase LH59_25790 f09ff676aca0c3060da2bec4680fa856 176 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 5 170 1.4E-33 T 14-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 LH59_25790 f09ff676aca0c3060da2bec4680fa856 176 Pfam PF02834 LigT like Phosphoesterase 11 88 6.7E-11 T 14-10-2018 IPR014051 Phosphoesterase, HXTX LH59_01705 9a776bb7a16c33dfcea1bb3b32bee400 165 Gene3D G3DSA:3.10.129.10 2 154 1.8E-54 T 14-10-2018 LH59_01705 9a776bb7a16c33dfcea1bb3b32bee400 165 Pfam PF03061 Thioesterase superfamily 24 97 3.7E-17 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 LH59_01705 9a776bb7a16c33dfcea1bb3b32bee400 165 SUPERFAMILY SSF54637 7 156 1.31E-43 T 14-10-2018 IPR029069 HotDog domain superfamily LH59_06165 11d6054ba243a9b26649932c333e9372 495 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 9 490 7.5E-184 T 14-10-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06165 11d6054ba243a9b26649932c333e9372 495 Pfam PF01059 NADH-ubiquinone oxidoreductase chain 4, amino terminus 66 128 2.3E-5 T 14-10-2018 IPR000260 NADH:ubiquinone oxidoreductase chain 4, N-terminal GO:0006120|GO:0055114 KEGG: 00190+1.6.5.3|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-5083|MetaCyc: PWY-6692|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06165 11d6054ba243a9b26649932c333e9372 495 Pfam PF00361 Proton-conducting membrane transporter 136 420 9.3E-78 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06165 11d6054ba243a9b26649932c333e9372 495 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 328 347 9.0E-49 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06165 11d6054ba243a9b26649932c333e9372 495 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 240 264 9.0E-49 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06165 11d6054ba243a9b26649932c333e9372 495 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 170 194 9.0E-49 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06165 11d6054ba243a9b26649932c333e9372 495 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 140 159 9.0E-49 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06165 11d6054ba243a9b26649932c333e9372 495 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 380 406 9.0E-49 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06965 e592ffb0435b35b0d05775f8651d9296 156 Pfam PF13412 Winged helix-turn-helix DNA-binding 7 54 1.7E-17 T 14-10-2018 LH59_06965 e592ffb0435b35b0d05775f8651d9296 156 SUPERFAMILY SSF46785 7 64 5.46E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_06965 e592ffb0435b35b0d05775f8651d9296 156 Gene3D G3DSA:3.30.70.920 60 156 3.7E-17 T 14-10-2018 LH59_06965 e592ffb0435b35b0d05775f8651d9296 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 34 2.8E-12 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_06965 e592ffb0435b35b0d05775f8651d9296 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 7 23 2.8E-12 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_06965 e592ffb0435b35b0d05775f8651d9296 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 53 2.8E-12 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_06965 e592ffb0435b35b0d05775f8651d9296 156 Gene3D G3DSA:1.10.10.10 8 59 7.6E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_06965 e592ffb0435b35b0d05775f8651d9296 156 SMART SM00344 7 116 2.0E-34 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 LH59_06965 e592ffb0435b35b0d05775f8651d9296 156 SUPERFAMILY SSF54909 70 156 2.15E-17 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel LH59_06965 e592ffb0435b35b0d05775f8651d9296 156 Pfam PF01037 Lrp/AsnC ligand binding domain 73 147 4.6E-17 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LH59_20935 7fa3280e861469f886d6a8ce9b63ec37 531 PIRSF PIRSF002741 22 517 6.7E-87 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 LH59_20935 7fa3280e861469f886d6a8ce9b63ec37 531 Gene3D G3DSA:3.40.190.10 190 510 1.4E-116 T 14-10-2018 LH59_20935 7fa3280e861469f886d6a8ce9b63ec37 531 Gene3D G3DSA:3.90.76.10 40 189 1.4E-116 T 14-10-2018 LH59_20935 7fa3280e861469f886d6a8ce9b63ec37 531 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 74 444 1.3E-77 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain LH59_20935 7fa3280e861469f886d6a8ce9b63ec37 531 Gene3D G3DSA:3.10.105.10 264 505 1.4E-116 T 14-10-2018 LH59_20935 7fa3280e861469f886d6a8ce9b63ec37 531 SUPERFAMILY SSF53850 31 511 1.21E-117 T 14-10-2018 LH59_17970 22c1a80fcd73215bc2ff4569f686663e 218 Gene3D G3DSA:3.40.50.300 1 217 3.0E-77 T 14-10-2018 LH59_17970 22c1a80fcd73215bc2ff4569f686663e 218 SUPERFAMILY SSF52540 1 190 3.91E-44 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_17970 22c1a80fcd73215bc2ff4569f686663e 218 TIGRFAM TIGR01351 adk: adenylate kinase 2 190 9.8E-74 T 14-10-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 LH59_17970 22c1a80fcd73215bc2ff4569f686663e 218 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 14-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 LH59_17970 22c1a80fcd73215bc2ff4569f686663e 218 Pfam PF05191 Adenylate kinase, active site lid 123 158 1.2E-17 T 14-10-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 LH59_17970 22c1a80fcd73215bc2ff4569f686663e 218 Pfam PF00406 Adenylate kinase 5 185 7.8E-58 T 14-10-2018 LH59_17970 22c1a80fcd73215bc2ff4569f686663e 218 PRINTS PR00094 Adenylate kinase signature 4 17 1.8E-35 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 LH59_17970 22c1a80fcd73215bc2ff4569f686663e 218 PRINTS PR00094 Adenylate kinase signature 173 187 1.8E-35 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 LH59_17970 22c1a80fcd73215bc2ff4569f686663e 218 PRINTS PR00094 Adenylate kinase signature 81 97 1.8E-35 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 LH59_17970 22c1a80fcd73215bc2ff4569f686663e 218 PRINTS PR00094 Adenylate kinase signature 156 171 1.8E-35 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 LH59_17970 22c1a80fcd73215bc2ff4569f686663e 218 PRINTS PR00094 Adenylate kinase signature 32 46 1.8E-35 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 LH59_17970 22c1a80fcd73215bc2ff4569f686663e 218 Hamap MF_00235 Adenylate kinase [adk]. 1 217 53.601 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 LH59_04835 b926d7e071c4ca89f50a1849f76f3a56 242 SUPERFAMILY SSF51735 5 238 1.48E-63 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_04835 b926d7e071c4ca89f50a1849f76f3a56 242 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 129 157 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LH59_04835 b926d7e071c4ca89f50a1849f76f3a56 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 161 3.8E-34 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_04835 b926d7e071c4ca89f50a1849f76f3a56 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 219 3.8E-34 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_04835 b926d7e071c4ca89f50a1849f76f3a56 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 117 133 3.8E-34 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_04835 b926d7e071c4ca89f50a1849f76f3a56 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 180 3.8E-34 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_04835 b926d7e071c4ca89f50a1849f76f3a56 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 70 81 3.8E-34 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_04835 b926d7e071c4ca89f50a1849f76f3a56 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 3.8E-34 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_04835 b926d7e071c4ca89f50a1849f76f3a56 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 123 131 4.8E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_04835 b926d7e071c4ca89f50a1849f76f3a56 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 70 81 4.8E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_04835 b926d7e071c4ca89f50a1849f76f3a56 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 161 4.8E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_04835 b926d7e071c4ca89f50a1849f76f3a56 242 Gene3D G3DSA:3.40.50.720 2 241 7.5E-65 T 14-10-2018 LH59_04835 b926d7e071c4ca89f50a1849f76f3a56 242 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 173 0.0068 T 14-10-2018 LH59_04835 b926d7e071c4ca89f50a1849f76f3a56 242 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 235 7.0E-43 T 14-10-2018 LH59_23040 77ef23f6824c8fd65517de984d36122f 379 Gene3D G3DSA:3.10.310.10 167 340 9.3E-123 T 14-10-2018 LH59_23040 77ef23f6824c8fd65517de984d36122f 379 Gene3D G3DSA:3.10.310.10 5 353 9.3E-123 T 14-10-2018 LH59_23040 77ef23f6824c8fd65517de984d36122f 379 SUPERFAMILY SSF54506 171 358 1.02E-54 T 14-10-2018 LH59_23040 77ef23f6824c8fd65517de984d36122f 379 SUPERFAMILY SSF54506 4 166 2.46E-64 T 14-10-2018 LH59_23040 77ef23f6824c8fd65517de984d36122f 379 Pfam PF04303 PrpF protein 5 356 8.8E-121 T 14-10-2018 IPR007400 PrpF protein LH59_16680 367e512625020098bedcfb181eadc7f1 325 SUPERFAMILY SSF46785 11 109 2.91E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_16680 367e512625020098bedcfb181eadc7f1 325 Pfam PF03466 LysR substrate binding domain 102 306 9.3E-31 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_16680 367e512625020098bedcfb181eadc7f1 325 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 52 5.1E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_16680 367e512625020098bedcfb181eadc7f1 325 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 52 63 5.1E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_16680 367e512625020098bedcfb181eadc7f1 325 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 42 5.1E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_16680 367e512625020098bedcfb181eadc7f1 325 Gene3D G3DSA:1.10.10.10 11 95 1.5E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_16680 367e512625020098bedcfb181eadc7f1 325 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 16 75 5.9E-20 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_16680 367e512625020098bedcfb181eadc7f1 325 SUPERFAMILY SSF53850 102 311 8.93E-34 T 14-10-2018 LH59_16680 367e512625020098bedcfb181eadc7f1 325 Gene3D G3DSA:3.40.190.290 104 313 2.8E-22 T 14-10-2018 LH59_10565 06f3c247d0a4acd4bf34816c1a22ead2 591 SUPERFAMILY SSF52016 394 580 3.3E-55 T 14-10-2018 LH59_10565 06f3c247d0a4acd4bf34816c1a22ead2 591 Pfam PF00920 Dehydratase family 58 573 1.1E-172 T 14-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 LH59_10565 06f3c247d0a4acd4bf34816c1a22ead2 591 SUPERFAMILY SSF143975 31 393 4.05E-113 T 14-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 LH59_10565 06f3c247d0a4acd4bf34816c1a22ead2 591 Gene3D G3DSA:3.50.30.80 394 548 3.7E-49 T 14-10-2018 LH59_10565 06f3c247d0a4acd4bf34816c1a22ead2 591 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 141 151 - T 14-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 LH59_10045 653d54d3fbf42e6f12e007101f33ed33 405 SUPERFAMILY SSF52343 262 400 4.58E-36 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain LH59_10045 653d54d3fbf42e6f12e007101f33ed33 405 Pfam PF00042 Globin 7 103 1.1E-11 T 14-10-2018 IPR000971 Globin GO:0020037 LH59_10045 653d54d3fbf42e6f12e007101f33ed33 405 Pfam PF00175 Oxidoreductase NAD-binding domain 272 380 2.8E-16 T 14-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 LH59_10045 653d54d3fbf42e6f12e007101f33ed33 405 SUPERFAMILY SSF46458 1 144 2.16E-41 T 14-10-2018 IPR009050 Globin-like superfamily LH59_10045 653d54d3fbf42e6f12e007101f33ed33 405 Pfam PF00970 Oxidoreductase FAD-binding domain 158 261 1.3E-7 T 14-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 LH59_10045 653d54d3fbf42e6f12e007101f33ed33 405 Gene3D G3DSA:3.40.50.80 264 401 7.7E-34 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain LH59_10045 653d54d3fbf42e6f12e007101f33ed33 405 SUPERFAMILY SSF63380 151 262 8.27E-30 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel LH59_10045 653d54d3fbf42e6f12e007101f33ed33 405 Gene3D G3DSA:2.40.30.10 151 261 1.1E-37 T 14-10-2018 LH59_10045 653d54d3fbf42e6f12e007101f33ed33 405 Gene3D G3DSA:1.10.490.10 1 144 4.7E-57 T 14-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 LH59_10045 653d54d3fbf42e6f12e007101f33ed33 405 Hamap MF_01252 Flavohemoprotein [hmp]. 1 404 55.99 T 14-10-2018 IPR023950 Flavohemoprotein GO:0008941|GO:0019825|GO:0020037|GO:0051409|GO:0055114|GO:0071949 LH59_02230 d6dcfc8bd15b57198c535b609a6ff1c9 292 TIGRFAM TIGR02957 SigX4: RNA polymerase sigma-70 factor, TIGR02957 family 7 285 9.1E-101 T 14-10-2018 IPR014303 RNA polymerase sigma-70, ECF type LH59_02230 d6dcfc8bd15b57198c535b609a6ff1c9 292 Gene3D G3DSA:1.10.1740.10 4 68 8.2E-13 T 14-10-2018 LH59_02230 d6dcfc8bd15b57198c535b609a6ff1c9 292 SUPERFAMILY SSF54427 171 287 2.93E-15 T 14-10-2018 IPR032710 NTF2-like domain superfamily LH59_02230 d6dcfc8bd15b57198c535b609a6ff1c9 292 Gene3D G3DSA:1.10.10.10 99 162 2.3E-13 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_02230 d6dcfc8bd15b57198c535b609a6ff1c9 292 SUPERFAMILY SSF88946 6 68 3.41E-16 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 LH59_02230 d6dcfc8bd15b57198c535b609a6ff1c9 292 Pfam PF04542 Sigma-70 region 2 7 68 1.4E-17 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 LH59_02230 d6dcfc8bd15b57198c535b609a6ff1c9 292 Gene3D G3DSA:3.10.450.50 165 267 5.7E-5 T 14-10-2018 LH59_02230 d6dcfc8bd15b57198c535b609a6ff1c9 292 Pfam PF08281 Sigma-70, region 4 107 158 1.7E-13 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LH59_02230 d6dcfc8bd15b57198c535b609a6ff1c9 292 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 6 160 2.3E-19 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 LH59_02230 d6dcfc8bd15b57198c535b609a6ff1c9 292 SUPERFAMILY SSF88659 102 160 1.01E-12 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like LH59_02285 0ae498e07338732d82623afa219f2062 345 Pfam PF00795 Carbon-nitrogen hydrolase 8 287 7.0E-41 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 LH59_02285 0ae498e07338732d82623afa219f2062 345 SUPERFAMILY SSF56317 6 310 1.1E-68 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily LH59_02285 0ae498e07338732d82623afa219f2062 345 Gene3D G3DSA:3.60.110.10 3 294 3.4E-99 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily LH59_11530 09dbf571da8fe78055affa4d4b95f357 558 Gene3D G3DSA:3.30.300.30 122 225 4.0E-13 T 14-10-2018 LH59_11530 09dbf571da8fe78055affa4d4b95f357 558 Pfam PF08345 Flagellar M-ring protein C-terminal 254 448 1.5E-47 T 14-10-2018 IPR013556 Flagellar M-ring C-terminal LH59_11530 09dbf571da8fe78055affa4d4b95f357 558 PRINTS PR01009 Flagellar M-ring protein signature 267 285 2.3E-40 T 14-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 LH59_11530 09dbf571da8fe78055affa4d4b95f357 558 PRINTS PR01009 Flagellar M-ring protein signature 376 400 2.3E-40 T 14-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 LH59_11530 09dbf571da8fe78055affa4d4b95f357 558 PRINTS PR01009 Flagellar M-ring protein signature 123 141 2.3E-40 T 14-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 LH59_11530 09dbf571da8fe78055affa4d4b95f357 558 PRINTS PR01009 Flagellar M-ring protein signature 155 169 2.3E-40 T 14-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 LH59_11530 09dbf571da8fe78055affa4d4b95f357 558 PRINTS PR01009 Flagellar M-ring protein signature 198 216 2.3E-40 T 14-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 LH59_11530 09dbf571da8fe78055affa4d4b95f357 558 Pfam PF01514 Secretory protein of YscJ/FliF family 33 222 2.0E-76 T 14-10-2018 IPR006182 Secretory protein YscJ/FliF LH59_11530 09dbf571da8fe78055affa4d4b95f357 558 PIRSF PIRSF004862 2 558 2.0E-152 T 14-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 LH59_11530 09dbf571da8fe78055affa4d4b95f357 558 TIGRFAM TIGR00206 fliF: flagellar M-ring protein FliF 17 556 1.1E-120 T 14-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 LH59_06425 101671dd65e96342109b0794e7cf2fd9 288 Gene3D G3DSA:3.20.20.70 3 283 2.5E-94 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_06425 101671dd65e96342109b0794e7cf2fd9 288 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 54 67 - T 14-10-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 LH59_06425 101671dd65e96342109b0794e7cf2fd9 288 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 21 253 6.7E-72 T 14-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 LH59_06425 101671dd65e96342109b0794e7cf2fd9 288 SUPERFAMILY SSF51366 8 253 3.11E-84 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 LH59_06425 101671dd65e96342109b0794e7cf2fd9 288 Pfam PF00290 Tryptophan synthase alpha chain 19 258 8.8E-85 T 14-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 LH59_06425 101671dd65e96342109b0794e7cf2fd9 288 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 19 277 33.289 T 14-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 LH59_27405 74057f9f9e90ed207e115b7f2de241f4 461 SUPERFAMILY SSF51905 216 450 4.63E-5 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_27405 74057f9f9e90ed207e115b7f2de241f4 461 SUPERFAMILY SSF51905 2 226 7.37E-14 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_27405 74057f9f9e90ed207e115b7f2de241f4 461 Pfam PF13454 FAD-NAD(P)-binding 6 160 3.2E-35 T 14-10-2018 IPR038732 FAD-dependent urate hydroxylase HpyO, FAD/NAD(P)-binding domain LH59_04375 2e23a5a1cff6baf0cd90bbdfa1ecefcd 521 SUPERFAMILY SSF54534 368 467 9.81E-34 T 14-10-2018 LH59_04375 2e23a5a1cff6baf0cd90bbdfa1ecefcd 521 SUPERFAMILY SSF109998 56 258 2.24E-38 T 14-10-2018 IPR027304 Trigger factor/SurA domain superfamily LH59_04375 2e23a5a1cff6baf0cd90bbdfa1ecefcd 521 Pfam PF13616 PPIC-type PPIASE domain 368 466 1.4E-26 T 14-10-2018 LH59_04375 2e23a5a1cff6baf0cd90bbdfa1ecefcd 521 Gene3D G3DSA:1.10.4030.30 53 223 3.9E-44 T 14-10-2018 LH59_04375 2e23a5a1cff6baf0cd90bbdfa1ecefcd 521 SUPERFAMILY SSF54534 230 330 1.05E-25 T 14-10-2018 LH59_04375 2e23a5a1cff6baf0cd90bbdfa1ecefcd 521 Pfam PF00639 PPIC-type PPIASE domain 235 328 1.2E-17 T 14-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 LH59_04375 2e23a5a1cff6baf0cd90bbdfa1ecefcd 521 Pfam PF09312 SurA N-terminal domain 56 173 1.6E-34 T 14-10-2018 IPR015391 SurA N-terminal LH59_04375 2e23a5a1cff6baf0cd90bbdfa1ecefcd 521 Hamap MF_01183 Chaperone SurA [surA]. 14 511 32.964 T 14-10-2018 IPR023034 Peptidyl-prolyl isomerase SurA GO:0003755|GO:0006457|GO:0030288|GO:0042277|GO:0043165|GO:0050821|GO:0051082|GO:0060274 LH59_15320 dab72324fd90eb5fede58ec771b13f48 201 Gene3D G3DSA:1.20.1050.10 83 188 3.8E-68 T 14-10-2018 LH59_15320 dab72324fd90eb5fede58ec771b13f48 201 Gene3D G3DSA:3.40.30.10 3 195 3.8E-68 T 14-10-2018 LH59_15320 dab72324fd90eb5fede58ec771b13f48 201 Pfam PF00043 Glutathione S-transferase, C-terminal domain 106 189 7.7E-8 T 14-10-2018 IPR004046 Glutathione S-transferase, C-terminal LH59_15320 dab72324fd90eb5fede58ec771b13f48 201 Pfam PF02798 Glutathione S-transferase, N-terminal domain 1 74 1.3E-6 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 LH59_15320 dab72324fd90eb5fede58ec771b13f48 201 SUPERFAMILY SSF52833 1 84 6.68E-17 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_15320 dab72324fd90eb5fede58ec771b13f48 201 SUPERFAMILY SSF47616 84 197 4.18E-23 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily LH59_24875 be89f5fc6f76a82b14af90e2b775544f 187 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 13 186 7.3E-47 T 14-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 LH59_24875 be89f5fc6f76a82b14af90e2b775544f 187 Hamap MF_00146 dCTP deaminase [dcd]. 2 187 27.932 T 14-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 LH59_24875 be89f5fc6f76a82b14af90e2b775544f 187 SUPERFAMILY SSF51283 3 186 3.4E-52 T 14-10-2018 IPR036157 dUTPase-like superfamily LH59_24875 be89f5fc6f76a82b14af90e2b775544f 187 Gene3D G3DSA:2.70.40.10 1 158 2.8E-49 T 14-10-2018 IPR036157 dUTPase-like superfamily LH59_24875 be89f5fc6f76a82b14af90e2b775544f 187 Pfam PF00692 dUTPase 81 183 4.7E-7 T 14-10-2018 IPR029054 dUTPase-like LH59_15060 e32bc800a1d90ac487a149c22e987954 544 Pfam PF00672 HAMP domain 220 267 5.7E-9 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_15060 e32bc800a1d90ac487a149c22e987954 544 SUPERFAMILY SSF58104 240 521 7.46E-74 T 14-10-2018 LH59_15060 e32bc800a1d90ac487a149c22e987954 544 SMART SM00283 273 520 7.6E-91 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 LH59_15060 e32bc800a1d90ac487a149c22e987954 544 SMART SM00304 220 272 9.5E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_15060 e32bc800a1d90ac487a149c22e987954 544 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 400 429 6.7E-60 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_15060 e32bc800a1d90ac487a149c22e987954 544 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 14 39 6.7E-60 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_15060 e32bc800a1d90ac487a149c22e987954 544 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 448 477 6.7E-60 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_15060 e32bc800a1d90ac487a149c22e987954 544 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 294 323 6.7E-60 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_15060 e32bc800a1d90ac487a149c22e987954 544 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 371 398 6.7E-60 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_15060 e32bc800a1d90ac487a149c22e987954 544 Gene3D G3DSA:1.10.287.950 219 522 7.2E-90 T 14-10-2018 LH59_15060 e32bc800a1d90ac487a149c22e987954 544 Pfam PF12729 Four helix bundle sensory module for signal transduction 13 191 2.9E-17 T 14-10-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain LH59_15060 e32bc800a1d90ac487a149c22e987954 544 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 332 488 1.2E-53 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 LH59_11760 379c0395652783ef99daaca15d48f3a6 396 SMART SM00267 211 382 8.4E-42 T 14-10-2018 IPR000160 GGDEF domain LH59_11760 379c0395652783ef99daaca15d48f3a6 396 Pfam PF00990 Diguanylate cyclase, GGDEF domain 222 378 1.8E-36 T 14-10-2018 IPR000160 GGDEF domain LH59_11760 379c0395652783ef99daaca15d48f3a6 396 SUPERFAMILY SSF55073 227 379 3.66E-43 T 14-10-2018 IPR029787 Nucleotide cyclase LH59_11760 379c0395652783ef99daaca15d48f3a6 396 Gene3D G3DSA:3.30.70.270 217 381 1.2E-48 T 14-10-2018 LH59_11760 379c0395652783ef99daaca15d48f3a6 396 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 219 379 7.6E-41 T 14-10-2018 IPR000160 GGDEF domain LH59_25860 ecd6cb5b2f13d180e183c863f75cc312 422 SUPERFAMILY SSF47005 139 182 3.92E-11 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 LH59_25860 ecd6cb5b2f13d180e183c863f75cc312 422 Gene3D G3DSA:2.40.50.100 2 104 4.7E-22 T 14-10-2018 LH59_25860 ecd6cb5b2f13d180e183c863f75cc312 422 Pfam PF00364 Biotin-requiring enzyme 5 76 6.1E-14 T 14-10-2018 IPR000089 Biotin/lipoyl attachment LH59_25860 ecd6cb5b2f13d180e183c863f75cc312 422 SUPERFAMILY SSF52777 199 422 4.45E-80 T 14-10-2018 LH59_25860 ecd6cb5b2f13d180e183c863f75cc312 422 Gene3D G3DSA:3.30.559.10 184 419 5.2E-94 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 LH59_25860 ecd6cb5b2f13d180e183c863f75cc312 422 Pfam PF02817 e3 binding domain 145 179 1.5E-13 T 14-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 LH59_25860 ecd6cb5b2f13d180e183c863f75cc312 422 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 198 421 1.3E-82 T 14-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 LH59_25860 ecd6cb5b2f13d180e183c863f75cc312 422 TIGRFAM TIGR01349 PDHac_trf_mito: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase 5 422 2.0E-143 T 14-10-2018 IPR006257 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex GO:0004742|GO:0006090|GO:0045254 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-70268 LH59_25860 ecd6cb5b2f13d180e183c863f75cc312 422 Gene3D G3DSA:4.10.320.10 132 183 1.9E-14 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 LH59_25860 ecd6cb5b2f13d180e183c863f75cc312 422 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 LH59_25860 ecd6cb5b2f13d180e183c863f75cc312 422 SUPERFAMILY SSF51230 4 94 7.07E-22 T 14-10-2018 IPR011053 Single hybrid motif LH59_18395 2274a173d46717eb9ca5a8a37c667b39 170 PIRSF PIRSF036158 1 170 3.1E-70 T 14-10-2018 IPR014601 Transcriptional regulator with MarR-type HTH domain LH59_18395 2274a173d46717eb9ca5a8a37c667b39 170 Gene3D G3DSA:1.10.10.10 8 166 2.9E-6 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_18395 2274a173d46717eb9ca5a8a37c667b39 170 SUPERFAMILY SSF46785 24 158 9.78E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_18395 2274a173d46717eb9ca5a8a37c667b39 170 Pfam PF13463 Winged helix DNA-binding domain 52 117 1.2E-18 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_08995 055511b84024de136b2064bdc7e55a51 653 SUPERFAMILY SSF56719 399 644 1.31E-74 T 14-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 LH59_08995 055511b84024de136b2064bdc7e55a51 653 Hamap MF_00938 DNA topoisomerase 4 subunit B [parE]. 3 651 44.685 T 14-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 LH59_08995 055511b84024de136b2064bdc7e55a51 653 Gene3D G3DSA:3.30.565.10 4 219 9.9E-68 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_08995 055511b84024de136b2064bdc7e55a51 653 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 579 643 4.7E-26 T 14-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 LH59_08995 055511b84024de136b2064bdc7e55a51 653 ProSitePatterns PS00177 DNA topoisomerase II signature. 426 434 - T 14-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 LH59_08995 055511b84024de136b2064bdc7e55a51 653 Pfam PF00204 DNA gyrase B 222 395 8.1E-33 T 14-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 LH59_08995 055511b84024de136b2064bdc7e55a51 653 SUPERFAMILY SSF55874 5 219 2.49E-60 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_08995 055511b84024de136b2064bdc7e55a51 653 PRINTS PR01098 Topoisomerase IV subunit B signature 27 40 7.1E-40 T 14-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 LH59_08995 055511b84024de136b2064bdc7e55a51 653 PRINTS PR01098 Topoisomerase IV subunit B signature 372 397 7.1E-40 T 14-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 LH59_08995 055511b84024de136b2064bdc7e55a51 653 PRINTS PR01098 Topoisomerase IV subunit B signature 458 479 7.1E-40 T 14-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 LH59_08995 055511b84024de136b2064bdc7e55a51 653 PRINTS PR01098 Topoisomerase IV subunit B signature 321 336 7.1E-40 T 14-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 LH59_08995 055511b84024de136b2064bdc7e55a51 653 PRINTS PR01098 Topoisomerase IV subunit B signature 348 371 7.1E-40 T 14-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 LH59_08995 055511b84024de136b2064bdc7e55a51 653 PRINTS PR01098 Topoisomerase IV subunit B signature 178 195 7.1E-40 T 14-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 LH59_08995 055511b84024de136b2064bdc7e55a51 653 PRINTS PR01098 Topoisomerase IV subunit B signature 304 320 7.1E-40 T 14-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 LH59_08995 055511b84024de136b2064bdc7e55a51 653 PRINTS PR01098 Topoisomerase IV subunit B signature 196 217 7.1E-40 T 14-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 LH59_08995 055511b84024de136b2064bdc7e55a51 653 Gene3D G3DSA:3.40.50.670 400 646 1.1E-84 T 14-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 LH59_08995 055511b84024de136b2064bdc7e55a51 653 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 35 175 1.4E-15 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_08995 055511b84024de136b2064bdc7e55a51 653 SMART SM00387 29 177 7.0E-19 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_08995 055511b84024de136b2064bdc7e55a51 653 SUPERFAMILY SSF54211 222 397 2.09E-36 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold LH59_08995 055511b84024de136b2064bdc7e55a51 653 PRINTS PR00418 DNA topoisomerase II family signature 67 80 2.8E-60 T 14-10-2018 LH59_08995 055511b84024de136b2064bdc7e55a51 653 PRINTS PR00418 DNA topoisomerase II family signature 531 543 2.8E-60 T 14-10-2018 LH59_08995 055511b84024de136b2064bdc7e55a51 653 PRINTS PR00418 DNA topoisomerase II family signature 113 127 2.8E-60 T 14-10-2018 LH59_08995 055511b84024de136b2064bdc7e55a51 653 PRINTS PR00418 DNA topoisomerase II family signature 276 289 2.8E-60 T 14-10-2018 LH59_08995 055511b84024de136b2064bdc7e55a51 653 PRINTS PR00418 DNA topoisomerase II family signature 32 47 2.8E-60 T 14-10-2018 LH59_08995 055511b84024de136b2064bdc7e55a51 653 PRINTS PR00418 DNA topoisomerase II family signature 424 438 2.8E-60 T 14-10-2018 LH59_08995 055511b84024de136b2064bdc7e55a51 653 PRINTS PR00418 DNA topoisomerase II family signature 583 599 2.8E-60 T 14-10-2018 LH59_08995 055511b84024de136b2064bdc7e55a51 653 PRINTS PR00418 DNA topoisomerase II family signature 511 528 2.8E-60 T 14-10-2018 LH59_08995 055511b84024de136b2064bdc7e55a51 653 PRINTS PR00418 DNA topoisomerase II family signature 493 509 2.8E-60 T 14-10-2018 LH59_08995 055511b84024de136b2064bdc7e55a51 653 SMART SM00433 34 647 1.5E-188 T 14-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 LH59_08995 055511b84024de136b2064bdc7e55a51 653 Pfam PF01751 Toprim domain 423 537 3.9E-12 T 14-10-2018 IPR006171 TOPRIM domain LH59_08995 055511b84024de136b2064bdc7e55a51 653 TIGRFAM TIGR01055 parE_Gneg: DNA topoisomerase IV, B subunit 5 647 3.9E-219 T 14-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 LH59_08995 055511b84024de136b2064bdc7e55a51 653 Gene3D G3DSA:3.30.230.10 220 399 2.6E-46 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup LH59_10250 664870f4539dfcbac98f4c1107792db0 540 Pfam PF00501 AMP-binding enzyme 38 440 1.0E-93 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 LH59_10250 664870f4539dfcbac98f4c1107792db0 540 ProSitePatterns PS00455 Putative AMP-binding domain signature. 190 201 - T 14-10-2018 IPR020845 AMP-binding, conserved site LH59_10250 664870f4539dfcbac98f4c1107792db0 540 SUPERFAMILY SSF56801 13 536 1.31E-146 T 14-10-2018 LH59_10250 664870f4539dfcbac98f4c1107792db0 540 Gene3D G3DSA:3.30.300.30 437 539 5.7E-30 T 14-10-2018 LH59_10250 664870f4539dfcbac98f4c1107792db0 540 Gene3D G3DSA:3.40.50.12780 15 436 4.7E-120 T 14-10-2018 LH59_10250 664870f4539dfcbac98f4c1107792db0 540 Pfam PF13193 AMP-binding enzyme C-terminal domain 451 528 1.8E-21 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain LH59_08870 56621ea3b64ad4a54087d69e89773393 435 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 333 422 2.9E-28 T 14-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 LH59_08870 56621ea3b64ad4a54087d69e89773393 435 Gene3D G3DSA:3.90.600.10 332 434 3.5E-33 T 14-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 LH59_08870 56621ea3b64ad4a54087d69e89773393 435 SUPERFAMILY SSF56059 102 323 2.12E-61 T 14-10-2018 LH59_08870 56621ea3b64ad4a54087d69e89773393 435 Gene3D G3DSA:3.30.470.20 189 331 1.9E-55 T 14-10-2018 LH59_08870 56621ea3b64ad4a54087d69e89773393 435 Gene3D G3DSA:3.30.1490.20 119 188 3.4E-28 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 LH59_08870 56621ea3b64ad4a54087d69e89773393 435 SUPERFAMILY SSF52440 1 101 4.03E-35 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily LH59_08870 56621ea3b64ad4a54087d69e89773393 435 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 298 1.0E-75 T 14-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 LH59_08870 56621ea3b64ad4a54087d69e89773393 435 SUPERFAMILY SSF51246 331 424 9.42E-30 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 LH59_08870 56621ea3b64ad4a54087d69e89773393 435 Gene3D G3DSA:3.40.50.20 1 93 3.7E-36 T 14-10-2018 LH59_08870 56621ea3b64ad4a54087d69e89773393 435 SMART SM01210 332 424 1.5E-51 T 14-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 LH59_08870 56621ea3b64ad4a54087d69e89773393 435 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 100 3.5E-36 T 14-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 LH59_08870 56621ea3b64ad4a54087d69e89773393 435 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 424 7.7E-167 T 14-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 LH59_08870 56621ea3b64ad4a54087d69e89773393 435 SMART SM01209 101 298 1.2E-134 T 14-10-2018 LH59_08870 56621ea3b64ad4a54087d69e89773393 435 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 424 41.71 T 14-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 LH59_27725 1ca21a7e104b7cf51eea8e7fdcf4a92f 328 SUPERFAMILY SSF55257 5 229 1.08E-31 T 14-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LH59_27725 1ca21a7e104b7cf51eea8e7fdcf4a92f 328 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 62 151 4.8E-24 T 14-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LH59_27725 1ca21a7e104b7cf51eea8e7fdcf4a92f 328 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 255 325 1.0E-34 T 14-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LH59_27725 1ca21a7e104b7cf51eea8e7fdcf4a92f 328 SMART SM00662 21 231 2.9E-99 T 14-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LH59_27725 1ca21a7e104b7cf51eea8e7fdcf4a92f 328 SUPERFAMILY SSF47789 250 322 1.07E-26 T 14-10-2018 LH59_27725 1ca21a7e104b7cf51eea8e7fdcf4a92f 328 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 22 315 7.4E-106 T 14-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LH59_27725 1ca21a7e104b7cf51eea8e7fdcf4a92f 328 SUPERFAMILY SSF56553 51 175 2.35E-42 T 14-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LH59_27725 1ca21a7e104b7cf51eea8e7fdcf4a92f 328 Gene3D G3DSA:2.170.120.12 51 174 4.2E-82 T 14-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LH59_27725 1ca21a7e104b7cf51eea8e7fdcf4a92f 328 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 250 307 9.8E-25 T 14-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LH59_27725 1ca21a7e104b7cf51eea8e7fdcf4a92f 328 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 3 316 35.569 T 14-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LH59_27725 1ca21a7e104b7cf51eea8e7fdcf4a92f 328 Gene3D G3DSA:1.10.150.20 244 327 1.2E-36 T 14-10-2018 LH59_27725 1ca21a7e104b7cf51eea8e7fdcf4a92f 328 Gene3D G3DSA:3.30.1360.10 18 224 4.2E-82 T 14-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LH59_27725 1ca21a7e104b7cf51eea8e7fdcf4a92f 328 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 27 224 7.3E-23 T 14-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LH59_15385 6954803235065ed36c27b2f00e02e848 218 SUPERFAMILY SSF103088 69 203 7.85E-29 T 14-10-2018 IPR036737 OmpA-like domain superfamily LH59_15385 6954803235065ed36c27b2f00e02e848 218 Gene3D G3DSA:3.30.1330.60 40 211 8.8E-39 T 14-10-2018 IPR036737 OmpA-like domain superfamily LH59_15385 6954803235065ed36c27b2f00e02e848 218 Pfam PF00691 OmpA family 94 198 6.9E-20 T 14-10-2018 IPR006665 OmpA-like domain LH59_06930 089da86ddeb1fef5ca1d3dc92c092bca 765 Gene3D G3DSA:3.40.50.720 162 445 1.2E-82 T 14-10-2018 LH59_06930 089da86ddeb1fef5ca1d3dc92c092bca 765 Gene3D G3DSA:3.40.50.10750 573 726 7.2E-92 T 14-10-2018 LH59_06930 089da86ddeb1fef5ca1d3dc92c092bca 765 Gene3D G3DSA:3.40.50.10950 446 750 7.2E-92 T 14-10-2018 LH59_06930 089da86ddeb1fef5ca1d3dc92c092bca 765 Pfam PF03949 Malic enzyme, NAD binding domain 166 361 2.4E-24 T 14-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 LH59_06930 089da86ddeb1fef5ca1d3dc92c092bca 765 SUPERFAMILY SSF53223 11 162 3.88E-49 T 14-10-2018 LH59_06930 089da86ddeb1fef5ca1d3dc92c092bca 765 Gene3D G3DSA:3.40.50.10380 1 161 1.2E-64 T 14-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 LH59_06930 089da86ddeb1fef5ca1d3dc92c092bca 765 SUPERFAMILY SSF51735 164 443 1.55E-85 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_06930 089da86ddeb1fef5ca1d3dc92c092bca 765 Pfam PF00390 Malic enzyme, N-terminal domain 19 152 1.9E-26 T 14-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 LH59_06930 089da86ddeb1fef5ca1d3dc92c092bca 765 SMART SM00919 164 401 1.0E-142 T 14-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 LH59_06930 089da86ddeb1fef5ca1d3dc92c092bca 765 SUPERFAMILY SSF53659 430 753 3.41E-89 T 14-10-2018 LH59_06930 089da86ddeb1fef5ca1d3dc92c092bca 765 Pfam PF01515 Phosphate acetyl/butaryl transferase 430 750 1.1E-95 T 14-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 LH59_06930 089da86ddeb1fef5ca1d3dc92c092bca 765 SMART SM01274 18 152 1.6E-75 T 14-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 LH59_06930 089da86ddeb1fef5ca1d3dc92c092bca 765 PIRSF PIRSF036684 1 758 0.0 T 14-10-2018 IPR012188 NAD(P)-dependent malic enzyme GO:0004470|GO:0006108|GO:0046872 KEGG: 00620+1.1.1.40|KEGG: 00710+1.1.1.40|MetaCyc: PWY-241|MetaCyc: PWY-7117 LH59_10800 2e4f1743056ca76fc439a41eb6d33406 862 PIRSF PIRSF001227 4 859 3.5E-112 T 14-10-2018 IPR014395 Penicillin/GL-7-ACA/AHL acylase GO:0016811 LH59_10800 2e4f1743056ca76fc439a41eb6d33406 862 SUPERFAMILY SSF56235 44 860 4.12E-209 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal LH59_10800 2e4f1743056ca76fc439a41eb6d33406 862 Gene3D G3DSA:1.10.1400.10 600 760 8.4E-218 T 14-10-2018 LH59_10800 2e4f1743056ca76fc439a41eb6d33406 862 Gene3D G3DSA:1.10.439.10 43 188 3.8E-51 T 14-10-2018 IPR023343 Penicillin amidase type, domain 1 GO:0016811 LH59_10800 2e4f1743056ca76fc439a41eb6d33406 862 Gene3D G3DSA:1.10.287.150 189 248 6.7E-24 T 14-10-2018 LH59_10800 2e4f1743056ca76fc439a41eb6d33406 862 Pfam PF01804 Penicillin amidase 45 849 1.7E-147 T 14-10-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 LH59_10800 2e4f1743056ca76fc439a41eb6d33406 862 Gene3D G3DSA:3.60.20.10 306 836 8.4E-218 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal LH59_10800 2e4f1743056ca76fc439a41eb6d33406 862 Gene3D G3DSA:2.30.120.10 378 450 8.4E-218 T 14-10-2018 LH59_03865 d5d034ae9260d7a82dfc3e190fd77064 210 Gene3D G3DSA:3.40.50.360 1 199 4.2E-56 T 14-10-2018 IPR029039 Flavoprotein-like superfamily LH59_03865 d5d034ae9260d7a82dfc3e190fd77064 210 Pfam PF02525 Flavodoxin-like fold 1 196 2.9E-46 T 14-10-2018 IPR003680 Flavodoxin-like fold LH59_03865 d5d034ae9260d7a82dfc3e190fd77064 210 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 1 199 30.328 T 14-10-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 LH59_03865 d5d034ae9260d7a82dfc3e190fd77064 210 SUPERFAMILY SSF52218 1 198 3.88E-54 T 14-10-2018 IPR029039 Flavoprotein-like superfamily LH59_09115 515c4d69951def4d4f22e6ecaab9249e 272 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 272 103.781 T 14-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 LH59_09115 515c4d69951def4d4f22e6ecaab9249e 272 Gene3D G3DSA:3.40.1280.10 1 176 1.7E-62 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal LH59_09115 515c4d69951def4d4f22e6ecaab9249e 272 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 234 1.4E-83 T 14-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 LH59_09115 515c4d69951def4d4f22e6ecaab9249e 272 SUPERFAMILY SSF75217 1 237 1.77E-88 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases LH59_09115 515c4d69951def4d4f22e6ecaab9249e 272 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 228 1.2E-55 T 14-10-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 LH59_09115 515c4d69951def4d4f22e6ecaab9249e 272 Gene3D G3DSA:1.10.1270.20 177 255 7.8E-26 T 14-10-2018 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 LH59_09115 515c4d69951def4d4f22e6ecaab9249e 272 PIRSF PIRSF000386 1 252 1.6E-85 T 14-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 LH59_01350 46bc9a3b3223f7b658c15234cda81b7a 276 PIRSF PIRSF000388 8 276 1.4E-99 T 14-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 LH59_01350 46bc9a3b3223f7b658c15234cda81b7a 276 Pfam PF02548 Ketopantoate hydroxymethyltransferase 16 270 1.5E-101 T 14-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 LH59_01350 46bc9a3b3223f7b658c15234cda81b7a 276 Gene3D G3DSA:3.20.20.60 15 276 1.1E-97 T 14-10-2018 LH59_01350 46bc9a3b3223f7b658c15234cda81b7a 276 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 18 275 8.3E-91 T 14-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 LH59_01350 46bc9a3b3223f7b658c15234cda81b7a 276 SUPERFAMILY SSF51621 16 275 1.48E-93 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 LH59_01350 46bc9a3b3223f7b658c15234cda81b7a 276 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 17 275 39.232 T 14-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 LH59_00800 ceebeeecc9c858eec8cc03c291374a6d 535 Gene3D G3DSA:3.90.76.10 38 194 4.5E-122 T 14-10-2018 LH59_00800 ceebeeecc9c858eec8cc03c291374a6d 535 PIRSF PIRSF002741 2 528 1.7E-89 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 LH59_00800 ceebeeecc9c858eec8cc03c291374a6d 535 SUPERFAMILY SSF53850 22 518 3.08E-127 T 14-10-2018 LH59_00800 ceebeeecc9c858eec8cc03c291374a6d 535 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 71 450 8.6E-92 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain LH59_00800 ceebeeecc9c858eec8cc03c291374a6d 535 Gene3D G3DSA:3.10.105.10 272 510 4.5E-122 T 14-10-2018 LH59_00800 ceebeeecc9c858eec8cc03c291374a6d 535 Gene3D G3DSA:3.40.190.10 195 518 4.5E-122 T 14-10-2018 LH59_08910 0eb26fc3cb8ce8481f79a5dd69f8fc79 166 ProSitePatterns PS01117 MarR-type HTH domain signature. 84 118 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site LH59_08910 0eb26fc3cb8ce8481f79a5dd69f8fc79 166 Gene3D G3DSA:1.10.10.10 7 159 5.9E-35 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_08910 0eb26fc3cb8ce8481f79a5dd69f8fc79 166 SMART SM00347 45 145 4.0E-20 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_08910 0eb26fc3cb8ce8481f79a5dd69f8fc79 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 85 5.7E-15 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_08910 0eb26fc3cb8ce8481f79a5dd69f8fc79 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 101 5.7E-15 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_08910 0eb26fc3cb8ce8481f79a5dd69f8fc79 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 105 121 5.7E-15 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_08910 0eb26fc3cb8ce8481f79a5dd69f8fc79 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 135 155 5.7E-15 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_08910 0eb26fc3cb8ce8481f79a5dd69f8fc79 166 Pfam PF01047 MarR family 70 110 6.4E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_08910 0eb26fc3cb8ce8481f79a5dd69f8fc79 166 SUPERFAMILY SSF46785 21 158 3.85E-33 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_24660 6af008e5146a18f9461dfd6693f30c38 471 Gene3D G3DSA:3.30.70.2190 215 340 2.1E-33 T 14-10-2018 LH59_24660 6af008e5146a18f9461dfd6693f30c38 471 Gene3D G3DSA:1.10.45.10 429 469 4.1E-20 T 14-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 LH59_24660 6af008e5146a18f9461dfd6693f30c38 471 Pfam PF01565 FAD binding domain 38 175 9.5E-37 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 LH59_24660 6af008e5146a18f9461dfd6693f30c38 471 Gene3D G3DSA:3.30.43.10 1 91 7.9E-25 T 14-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 LH59_24660 6af008e5146a18f9461dfd6693f30c38 471 SUPERFAMILY SSF55103 218 469 9.81E-57 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 LH59_24660 6af008e5146a18f9461dfd6693f30c38 471 SUPERFAMILY SSF56176 3 215 1.04E-77 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 LH59_24660 6af008e5146a18f9461dfd6693f30c38 471 Gene3D G3DSA:3.30.70.2740 342 428 8.5E-27 T 14-10-2018 LH59_24660 6af008e5146a18f9461dfd6693f30c38 471 Gene3D G3DSA:3.30.465.10 93 214 7.4E-46 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 LH59_24660 6af008e5146a18f9461dfd6693f30c38 471 Pfam PF02913 FAD linked oxidases, C-terminal domain 216 468 1.0E-51 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 LH59_19860 09cc345fd2b1097914a0c9bc778425eb 565 ProSitePatterns PS00211 ABC transporters family signature. 453 467 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_19860 09cc345fd2b1097914a0c9bc778425eb 565 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 242 274 3.9E-5 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_19860 09cc345fd2b1097914a0c9bc778425eb 565 SMART SM00382 41 240 1.2E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_19860 09cc345fd2b1097914a0c9bc778425eb 565 SMART SM00382 335 530 1.4E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_19860 09cc345fd2b1097914a0c9bc778425eb 565 Pfam PF00005 ABC transporter 327 481 1.3E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_19860 09cc345fd2b1097914a0c9bc778425eb 565 Pfam PF00005 ABC transporter 33 190 9.1E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_19860 09cc345fd2b1097914a0c9bc778425eb 565 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_19860 09cc345fd2b1097914a0c9bc778425eb 565 Gene3D G3DSA:3.40.50.300 10 296 1.6E-81 T 14-10-2018 LH59_19860 09cc345fd2b1097914a0c9bc778425eb 565 Gene3D G3DSA:3.40.50.300 297 563 4.4E-86 T 14-10-2018 LH59_19860 09cc345fd2b1097914a0c9bc778425eb 565 SUPERFAMILY SSF52540 12 262 6.18E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_19860 09cc345fd2b1097914a0c9bc778425eb 565 SUPERFAMILY SSF52540 299 551 2.77E-68 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_20765 dd0a9c1b00f18d940aee18f0744c532d 235 SUPERFAMILY SSF52172 1 146 4.41E-22 T 14-10-2018 IPR011006 CheY-like superfamily LH59_20765 dd0a9c1b00f18d940aee18f0744c532d 235 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 219 3.1E-6 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_20765 dd0a9c1b00f18d940aee18f0744c532d 235 SMART SM00448 1 112 2.9E-7 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_20765 dd0a9c1b00f18d940aee18f0744c532d 235 Gene3D G3DSA:3.40.50.2300 1 116 4.5E-17 T 14-10-2018 LH59_20765 dd0a9c1b00f18d940aee18f0744c532d 235 SMART SM00862 146 222 0.0015 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_20765 dd0a9c1b00f18d940aee18f0744c532d 235 Pfam PF00072 Response regulator receiver domain 3 108 7.3E-9 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_20765 dd0a9c1b00f18d940aee18f0744c532d 235 Gene3D G3DSA:1.10.10.10 117 222 2.4E-12 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_20765 dd0a9c1b00f18d940aee18f0744c532d 235 SUPERFAMILY SSF46894 130 222 5.95E-12 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LH59_06880 a8f5f22868bbed7150580bb79b42a5dc 329 Gene3D G3DSA:3.40.50.720 1 157 2.7E-60 T 14-10-2018 LH59_06880 a8f5f22868bbed7150580bb79b42a5dc 329 SUPERFAMILY SSF51735 5 158 1.79E-46 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_06880 a8f5f22868bbed7150580bb79b42a5dc 329 Hamap MF_01517 Malate dehydrogenase [mdh]. 2 328 56.916 T 14-10-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 LH59_06880 a8f5f22868bbed7150580bb79b42a5dc 329 Gene3D G3DSA:3.90.110.10 158 329 3.1E-61 T 14-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 LH59_06880 a8f5f22868bbed7150580bb79b42a5dc 329 PIRSF PIRSF000102 2 328 1.9E-64 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 LH59_06880 a8f5f22868bbed7150580bb79b42a5dc 329 TIGRFAM TIGR01759 MalateDH-SF1: malate dehydrogenase 5 322 1.8E-143 T 14-10-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 LH59_06880 a8f5f22868bbed7150580bb79b42a5dc 329 SUPERFAMILY SSF56327 160 328 5.25E-60 T 14-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 LH59_06880 a8f5f22868bbed7150580bb79b42a5dc 329 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 155 7.1E-38 T 14-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 LH59_06880 a8f5f22868bbed7150580bb79b42a5dc 329 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 160 324 5.6E-31 T 14-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 LH59_04550 fa6c26c26a22d635eb9514c0de430207 298 PRINTS PR00990 Ribokinase signature 200 211 7.9E-6 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 LH59_04550 fa6c26c26a22d635eb9514c0de430207 298 PRINTS PR00990 Ribokinase signature 33 52 7.9E-6 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 LH59_04550 fa6c26c26a22d635eb9514c0de430207 298 PRINTS PR00990 Ribokinase signature 6 27 7.9E-6 T 14-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 LH59_04550 fa6c26c26a22d635eb9514c0de430207 298 Gene3D G3DSA:3.40.1190.20 3 296 1.8E-49 T 14-10-2018 IPR029056 Ribokinase-like LH59_04550 fa6c26c26a22d635eb9514c0de430207 298 SUPERFAMILY SSF53613 4 289 9.67E-49 T 14-10-2018 IPR029056 Ribokinase-like LH59_04550 fa6c26c26a22d635eb9514c0de430207 298 Pfam PF00294 pfkB family carbohydrate kinase 5 281 2.2E-22 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB LH59_04550 fa6c26c26a22d635eb9514c0de430207 298 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 233 246 - T 14-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 LH59_25165 dfe27325c2c13bb7931ca32316120e26 321 PIRSF PIRSF018266 4 321 1.3E-84 T 14-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component LH59_25165 dfe27325c2c13bb7931ca32316120e26 321 Pfam PF04773 FecR protein 112 207 1.7E-20 T 14-10-2018 IPR006860 FecR protein LH59_25165 dfe27325c2c13bb7931ca32316120e26 321 Pfam PF16220 Domain of unknown function (DUF4880) 15 57 4.5E-13 T 14-10-2018 IPR032623 FecR, N-terminal LH59_25165 dfe27325c2c13bb7931ca32316120e26 321 Gene3D G3DSA:2.60.120.1440 102 236 1.3E-16 T 14-10-2018 LH59_01290 7d33b1657185f62101828d574f7173be 265 Gene3D G3DSA:3.40.50.150 31 256 3.8E-43 T 14-10-2018 LH59_01290 7d33b1657185f62101828d574f7173be 265 SUPERFAMILY SSF53335 35 234 4.0E-41 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_01290 7d33b1657185f62101828d574f7173be 265 Pfam PF01564 Spermine/spermidine synthase domain 62 201 1.0E-10 T 14-10-2018 LH59_10710 e9e3d671de371094afa68da8e21a2ca0 334 SUPERFAMILY SSF53850 38 286 1.16E-10 T 14-10-2018 LH59_10710 e9e3d671de371094afa68da8e21a2ca0 334 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 56 330 7.7E-81 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_10710 e9e3d671de371094afa68da8e21a2ca0 334 PIRSF PIRSF017082 1 334 2.0E-73 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_10710 e9e3d671de371094afa68da8e21a2ca0 334 Gene3D G3DSA:3.40.190.10 134 259 1.1E-99 T 14-10-2018 LH59_10710 e9e3d671de371094afa68da8e21a2ca0 334 Gene3D G3DSA:3.40.190.150 36 323 1.1E-99 T 14-10-2018 LH59_10675 8f1c11258fcb76b1a19c8e83ded3514b 261 SMART SM01007 32 210 1.1E-39 T 14-10-2018 IPR001303 Class II aldolase/adducin N-terminal LH59_10675 8f1c11258fcb76b1a19c8e83ded3514b 261 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 33 210 4.2E-35 T 14-10-2018 IPR001303 Class II aldolase/adducin N-terminal LH59_10675 8f1c11258fcb76b1a19c8e83ded3514b 261 Gene3D G3DSA:3.40.225.10 18 251 2.6E-48 T 14-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily LH59_10675 8f1c11258fcb76b1a19c8e83ded3514b 261 SUPERFAMILY SSF53639 28 235 5.3E-51 T 14-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily LH59_21475 258ab48623524405cdafe83daee03e98 594 SUPERFAMILY SSF52091 455 565 6.47E-15 T 14-10-2018 IPR036513 STAS domain superfamily LH59_21475 258ab48623524405cdafe83daee03e98 594 Pfam PF01740 STAS domain 457 560 5.1E-11 T 14-10-2018 IPR002645 STAS domain LH59_21475 258ab48623524405cdafe83daee03e98 594 Pfam PF00916 Sulfate permease family 25 398 2.7E-81 T 14-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 LH59_21475 258ab48623524405cdafe83daee03e98 594 Gene3D G3DSA:3.30.750.24 446 570 8.0E-23 T 14-10-2018 IPR036513 STAS domain superfamily LH59_05290 651c76950b1b51cbc614ec68140b0064 334 SUPERFAMILY SSF55781 68 332 1.41E-60 T 14-10-2018 LH59_05290 651c76950b1b51cbc614ec68140b0064 334 SUPERFAMILY SSF46785 1 79 7.1E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_05290 651c76950b1b51cbc614ec68140b0064 334 Gene3D G3DSA:1.10.10.10 1 81 3.9E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_05290 651c76950b1b51cbc614ec68140b0064 334 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 2 329 1.5E-91 T 14-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 LH59_05290 651c76950b1b51cbc614ec68140b0064 334 PIRSF PIRSF005485 1 334 1.4E-106 T 14-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 LH59_05290 651c76950b1b51cbc614ec68140b0064 334 Gene3D G3DSA:3.30.450.40 101 329 5.7E-37 T 14-10-2018 IPR029016 GAF-like domain superfamily LH59_05290 651c76950b1b51cbc614ec68140b0064 334 Gene3D G3DSA:3.30.390.60 122 220 5.7E-37 T 14-10-2018 IPR023120 Winged helix-turn-helix transcription repressor, HrcA, inserted dimerising domain superfamily LH59_05290 651c76950b1b51cbc614ec68140b0064 334 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 1 323 25.921 T 14-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 LH59_05290 651c76950b1b51cbc614ec68140b0064 334 Pfam PF03444 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 6 70 1.4E-7 T 14-10-2018 IPR005104 Winged helix-turn-helix transcription repressor, HrcA DNA-binding domain GO:0003677|GO:0006355 LH59_05290 651c76950b1b51cbc614ec68140b0064 334 Pfam PF01628 HrcA protein C terminal domain 100 316 2.5E-57 T 14-10-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 LH59_17160 0c7fdfd1b5870b0d2e80c13ee390f235 64 Gene3D G3DSA:1.10.10.600 1 64 1.3E-31 T 14-10-2018 IPR036762 IscX-like superfamily LH59_17160 0c7fdfd1b5870b0d2e80c13ee390f235 64 Pfam PF04384 Iron-sulphur cluster assembly 1 63 4.4E-34 T 14-10-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 LH59_17160 0c7fdfd1b5870b0d2e80c13ee390f235 64 PIRSF PIRSF039003 1 64 1.3E-35 T 14-10-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 LH59_17160 0c7fdfd1b5870b0d2e80c13ee390f235 64 SUPERFAMILY SSF140319 1 62 2.88E-27 T 14-10-2018 IPR036762 IscX-like superfamily LH59_17160 0c7fdfd1b5870b0d2e80c13ee390f235 64 TIGRFAM TIGR03412 iscX_yfhJ: FeS assembly protein IscX 2 64 1.8E-35 T 14-10-2018 IPR007479 ISC system FeS cluster assembly, IscX GO:0016226 LH59_28100 0d94ddd47b461af9d47216493486132c 334 Pfam PF00710 Asparaginase, N-terminal 9 195 8.5E-56 T 14-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 LH59_28100 0d94ddd47b461af9d47216493486132c 334 Gene3D G3DSA:3.40.50.1170 3 218 7.8E-78 T 14-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 LH59_28100 0d94ddd47b461af9d47216493486132c 334 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 89 99 - T 14-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 LH59_28100 0d94ddd47b461af9d47216493486132c 334 Gene3D G3DSA:3.40.50.40 222 334 1.1E-36 T 14-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 LH59_28100 0d94ddd47b461af9d47216493486132c 334 PIRSF PIRSF500176 6 332 3.6E-78 T 14-10-2018 LH59_28100 0d94ddd47b461af9d47216493486132c 334 SMART SM00870 8 328 3.3E-122 T 14-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 LH59_28100 0d94ddd47b461af9d47216493486132c 334 PRINTS PR00139 Asparaginase/glutaminase family signature 9 20 5.9E-21 T 14-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 LH59_28100 0d94ddd47b461af9d47216493486132c 334 PRINTS PR00139 Asparaginase/glutaminase family signature 268 286 5.9E-21 T 14-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 LH59_28100 0d94ddd47b461af9d47216493486132c 334 PRINTS PR00139 Asparaginase/glutaminase family signature 88 106 5.9E-21 T 14-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 LH59_28100 0d94ddd47b461af9d47216493486132c 334 TIGRFAM TIGR00520 asnASE_II: L-asparaginase, type II 3 334 3.7E-114 T 14-10-2018 IPR004550 L-asparaginase, type II GO:0004067|GO:0006528 LH59_28100 0d94ddd47b461af9d47216493486132c 334 SUPERFAMILY SSF53774 5 333 1.7E-94 T 14-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 LH59_28100 0d94ddd47b461af9d47216493486132c 334 PIRSF PIRSF001220 3 333 1.5E-83 T 14-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 LH59_28100 0d94ddd47b461af9d47216493486132c 334 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 11 19 - T 14-10-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 LH59_27110 0d09430ddcce692d0926901cf39b7c72 468 Pfam PF01425 Amidase 23 444 3.4E-89 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_27110 0d09430ddcce692d0926901cf39b7c72 468 ProSitePatterns PS00571 Amidases signature. 151 182 - T 14-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 LH59_27110 0d09430ddcce692d0926901cf39b7c72 468 SUPERFAMILY SSF75304 3 461 5.63E-112 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_27110 0d09430ddcce692d0926901cf39b7c72 468 Gene3D G3DSA:3.90.1300.10 3 453 2.0E-116 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_08580 b165d72d311b806342c858503ce895e8 255 SUPERFAMILY SSF53474 9 249 5.46E-37 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_08580 b165d72d311b806342c858503ce895e8 255 Gene3D G3DSA:3.40.50.1820 2 254 2.3E-37 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_08580 b165d72d311b806342c858503ce895e8 255 Pfam PF12697 Alpha/beta hydrolase family 22 245 3.1E-12 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_10470 490ed5391d1e2978cf27959960562065 1053 Gene3D G3DSA:3.40.50.740 84 747 8.4E-68 T 14-10-2018 LH59_10470 490ed5391d1e2978cf27959960562065 1053 SUPERFAMILY SSF53706 85 922 5.56E-105 T 14-10-2018 LH59_10470 490ed5391d1e2978cf27959960562065 1053 Gene3D G3DSA:2.40.40.20 880 1023 3.5E-22 T 14-10-2018 LH59_10470 490ed5391d1e2978cf27959960562065 1053 Pfam PF00384 Molybdopterin oxidoreductase 260 713 5.5E-9 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_10470 490ed5391d1e2978cf27959960562065 1053 SMART SM00926 85 167 1.7E-11 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_10470 490ed5391d1e2978cf27959960562065 1053 SUPERFAMILY SSF50692 903 1052 1.74E-24 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily LH59_10470 490ed5391d1e2978cf27959960562065 1053 Pfam PF01568 Molydopterin dinucleotide binding domain 923 1018 6.8E-12 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 LH59_27665 257db21f429106f73e88d02e99709728 109 Hamap MF_00142 Iron-sulfur cluster assembly protein CyaY [cyaY]. 1 107 23.627 T 14-10-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 LH59_27665 257db21f429106f73e88d02e99709728 109 Gene3D G3DSA:3.30.920.10 1 108 1.8E-34 T 14-10-2018 IPR036524 Frataxin/CyaY superfamily GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 LH59_27665 257db21f429106f73e88d02e99709728 109 TIGRFAM TIGR03421 FeS_CyaY: iron donor protein CyaY 2 106 9.0E-34 T 14-10-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 LH59_27665 257db21f429106f73e88d02e99709728 109 SUPERFAMILY SSF55387 1 107 4.36E-29 T 14-10-2018 LH59_27665 257db21f429106f73e88d02e99709728 109 Pfam PF01491 Frataxin-like domain 1 103 1.9E-21 T 14-10-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 LH59_27665 257db21f429106f73e88d02e99709728 109 ProSitePatterns PS01344 Frataxin family signature. 52 66 - T 14-10-2018 IPR020895 Frataxin conserved site Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 LH59_27665 257db21f429106f73e88d02e99709728 109 SMART SM01219 1 108 6.0E-38 T 14-10-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 LH59_17895 d7ddb8db8fcb22dd3deba38e61b41903 104 SUPERFAMILY SSF54736 21 103 2.93E-32 T 14-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like LH59_17895 d7ddb8db8fcb22dd3deba38e61b41903 104 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 3 99 29.091 T 14-10-2018 IPR022935 ATP-dependent Clp protease adaptor protein ClpS LH59_17895 d7ddb8db8fcb22dd3deba38e61b41903 104 Gene3D G3DSA:3.30.1390.10 2 104 3.0E-43 T 14-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like LH59_17895 d7ddb8db8fcb22dd3deba38e61b41903 104 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 22 99 8.3E-36 T 14-10-2018 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 LH59_06475 46609a6883bc71318da816c45fbe7be6 200 TIGRFAM TIGR00172 maf: septum formation protein Maf 5 185 3.8E-40 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 LH59_06475 46609a6883bc71318da816c45fbe7be6 200 Gene3D G3DSA:3.90.950.10 5 195 1.6E-53 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like LH59_06475 46609a6883bc71318da816c45fbe7be6 200 Hamap MF_00528 Septum formation protein Maf [maf]. 6 192 28.074 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 LH59_06475 46609a6883bc71318da816c45fbe7be6 200 Pfam PF02545 Maf-like protein 7 186 1.9E-41 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 LH59_06475 46609a6883bc71318da816c45fbe7be6 200 SUPERFAMILY SSF52972 5 186 7.19E-53 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like LH59_06475 46609a6883bc71318da816c45fbe7be6 200 PIRSF PIRSF006305 1 194 8.6E-47 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 LH59_27790 e767f0d7a4658323aa95e7bc4f03338c 179 Pfam PF00673 ribosomal L5P family C-terminus 84 177 2.6E-40 T 14-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27790 e767f0d7a4658323aa95e7bc4f03338c 179 SUPERFAMILY SSF55282 3 179 5.18E-76 T 14-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27790 e767f0d7a4658323aa95e7bc4f03338c 179 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 1 179 43.43 T 14-10-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_27790 e767f0d7a4658323aa95e7bc4f03338c 179 ProSitePatterns PS00358 Ribosomal protein L5 signature. 57 73 - T 14-10-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27790 e767f0d7a4658323aa95e7bc4f03338c 179 Pfam PF00281 Ribosomal protein L5 25 80 8.3E-26 T 14-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27790 e767f0d7a4658323aa95e7bc4f03338c 179 PIRSF PIRSF002161 1 179 3.3E-62 T 14-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27790 e767f0d7a4658323aa95e7bc4f03338c 179 Gene3D G3DSA:3.30.1440.10 1 179 1.3E-76 T 14-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_25920 0010648a86a5e5519d81aeac5d5c8209 311 PIRSF PIRSF000105 1 305 1.0E-92 T 14-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 LH59_25920 0010648a86a5e5519d81aeac5d5c8209 311 SUPERFAMILY SSF48179 182 288 2.13E-25 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 LH59_25920 0010648a86a5e5519d81aeac5d5c8209 311 Gene3D G3DSA:3.40.50.720 1 179 1.1E-63 T 14-10-2018 LH59_25920 0010648a86a5e5519d81aeac5d5c8209 311 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 183 281 8.8E-24 T 14-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 LH59_25920 0010648a86a5e5519d81aeac5d5c8209 311 SUPERFAMILY SSF51735 5 179 1.67E-52 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_25920 0010648a86a5e5519d81aeac5d5c8209 311 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 8 180 1.5E-59 T 14-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 LH59_25920 0010648a86a5e5519d81aeac5d5c8209 311 Gene3D G3DSA:1.10.1040.10 185 308 2.2E-40 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 LH59_10130 e4363ecb25f0c4eea943f0c96ce4ee97 589 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 161 270 4.1E-16 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 LH59_10130 e4363ecb25f0c4eea943f0c96ce4ee97 589 Gene3D G3DSA:1.10.540.10 32 157 7.2E-20 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 LH59_10130 e4363ecb25f0c4eea943f0c96ce4ee97 589 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 2 33 4.7E-11 T 14-10-2018 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria LH59_10130 e4363ecb25f0c4eea943f0c96ce4ee97 589 Gene3D G3DSA:2.40.110.10 159 288 2.9E-27 T 14-10-2018 LH59_10130 e4363ecb25f0c4eea943f0c96ce4ee97 589 Gene3D G3DSA:1.20.140.10 289 454 1.0E-47 T 14-10-2018 LH59_10130 e4363ecb25f0c4eea943f0c96ce4ee97 589 SUPERFAMILY SSF56645 34 280 5.1E-62 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 LH59_10130 e4363ecb25f0c4eea943f0c96ce4ee97 589 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 35 155 6.2E-15 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 LH59_10130 e4363ecb25f0c4eea943f0c96ce4ee97 589 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 283 449 7.8E-26 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LH59_10130 e4363ecb25f0c4eea943f0c96ce4ee97 589 SUPERFAMILY SSF47203 289 465 1.01E-43 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 LH59_10130 e4363ecb25f0c4eea943f0c96ce4ee97 589 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 465 580 1.4E-19 T 14-10-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain LH59_25780 90f4f65321ca29695a248d0122a5fc2b 1071 Gene3D G3DSA:3.30.70.1320 135 335 0.0 T 14-10-2018 LH59_25780 90f4f65321ca29695a248d0122a5fc2b 1071 SUPERFAMILY SSF82693 575 681 1.73E-26 T 14-10-2018 LH59_25780 90f4f65321ca29695a248d0122a5fc2b 1071 Gene3D G3DSA:3.30.70.1430 40 827 0.0 T 14-10-2018 LH59_25780 90f4f65321ca29695a248d0122a5fc2b 1071 Gene3D G3DSA:3.30.70.1440 679 876 0.0 T 14-10-2018 LH59_25780 90f4f65321ca29695a248d0122a5fc2b 1071 SUPERFAMILY SSF82693 682 867 6.28E-26 T 14-10-2018 LH59_25780 90f4f65321ca29695a248d0122a5fc2b 1071 Gene3D G3DSA:1.20.1640.10 523 1033 0.0 T 14-10-2018 LH59_25780 90f4f65321ca29695a248d0122a5fc2b 1071 SUPERFAMILY SSF82866 299 499 1.31E-53 T 14-10-2018 LH59_25780 90f4f65321ca29695a248d0122a5fc2b 1071 SUPERFAMILY SSF82693 41 134 4.19E-26 T 14-10-2018 LH59_25780 90f4f65321ca29695a248d0122a5fc2b 1071 Pfam PF00873 AcrB/AcrD/AcrF family 3 1036 0.0 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_25780 90f4f65321ca29695a248d0122a5fc2b 1071 Gene3D G3DSA:1.20.1640.10 10 522 0.0 T 14-10-2018 LH59_25780 90f4f65321ca29695a248d0122a5fc2b 1071 PRINTS PR00702 Acriflavin resistance protein family signature 562 579 1.2E-91 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_25780 90f4f65321ca29695a248d0122a5fc2b 1071 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.2E-91 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_25780 90f4f65321ca29695a248d0122a5fc2b 1071 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.2E-91 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_25780 90f4f65321ca29695a248d0122a5fc2b 1071 PRINTS PR00702 Acriflavin resistance protein family signature 339 362 1.2E-91 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_25780 90f4f65321ca29695a248d0122a5fc2b 1071 PRINTS PR00702 Acriflavin resistance protein family signature 447 470 1.2E-91 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_25780 90f4f65321ca29695a248d0122a5fc2b 1071 PRINTS PR00702 Acriflavin resistance protein family signature 366 387 1.2E-91 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_25780 90f4f65321ca29695a248d0122a5fc2b 1071 PRINTS PR00702 Acriflavin resistance protein family signature 631 645 1.2E-91 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_25780 90f4f65321ca29695a248d0122a5fc2b 1071 PRINTS PR00702 Acriflavin resistance protein family signature 394 418 1.2E-91 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_25780 90f4f65321ca29695a248d0122a5fc2b 1071 PRINTS PR00702 Acriflavin resistance protein family signature 472 495 1.2E-91 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_25780 90f4f65321ca29695a248d0122a5fc2b 1071 SUPERFAMILY SSF82693 139 333 1.26E-26 T 14-10-2018 LH59_25780 90f4f65321ca29695a248d0122a5fc2b 1071 SUPERFAMILY SSF82714 732 818 2.49E-20 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_25780 90f4f65321ca29695a248d0122a5fc2b 1071 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 4 1046 0.0 T 14-10-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0006855|GO:0015562|GO:0016021 LH59_25780 90f4f65321ca29695a248d0122a5fc2b 1071 Gene3D G3DSA:3.30.70.1430 577 678 0.0 T 14-10-2018 LH59_25780 90f4f65321ca29695a248d0122a5fc2b 1071 Gene3D G3DSA:3.30.2090.10 181 278 0.0 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_25780 90f4f65321ca29695a248d0122a5fc2b 1071 SUPERFAMILY SSF82714 185 274 2.88E-20 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_25780 90f4f65321ca29695a248d0122a5fc2b 1071 Gene3D G3DSA:3.30.2090.10 731 819 0.0 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_25780 90f4f65321ca29695a248d0122a5fc2b 1071 SUPERFAMILY SSF82866 841 1036 1.96E-46 T 14-10-2018 LH59_04710 13dc0f8bc0ed44084310d7ddde12546c 209 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 9 209 39.358 T 14-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 LH59_04710 13dc0f8bc0ed44084310d7ddde12546c 209 SUPERFAMILY SSF50475 6 209 5.8E-69 T 14-10-2018 LH59_04710 13dc0f8bc0ed44084310d7ddde12546c 209 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 32 118 5.7E-28 T 14-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 LH59_04710 13dc0f8bc0ed44084310d7ddde12546c 209 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 179 192 - T 14-10-2018 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 LH59_04710 13dc0f8bc0ed44084310d7ddde12546c 209 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 2 209 9.4E-87 T 14-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 LH59_04710 13dc0f8bc0ed44084310d7ddde12546c 209 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 169 209 2.4E-21 T 14-10-2018 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 LH59_04710 13dc0f8bc0ed44084310d7ddde12546c 209 Gene3D G3DSA:2.30.110.10 1 209 8.8E-90 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 LH59_04710 13dc0f8bc0ed44084310d7ddde12546c 209 PIRSF PIRSF000190 1 209 1.8E-83 T 14-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 LH59_00685 db24336cbbe761ebf4820a0570f2012e 442 Pfam PF01425 Amidase 27 415 1.8E-87 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_00685 db24336cbbe761ebf4820a0570f2012e 442 SUPERFAMILY SSF75304 5 423 9.81E-120 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_00685 db24336cbbe761ebf4820a0570f2012e 442 Gene3D G3DSA:3.90.1300.10 8 428 1.7E-132 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_23385 77b039b268d629da4ba03a778fa54beb 320 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 20 77 1.8E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_23385 77b039b268d629da4ba03a778fa54beb 320 Gene3D G3DSA:1.10.10.10 16 104 6.5E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_23385 77b039b268d629da4ba03a778fa54beb 320 Gene3D G3DSA:3.40.190.10 182 286 1.6E-28 T 14-10-2018 LH59_23385 77b039b268d629da4ba03a778fa54beb 320 Pfam PF03466 LysR substrate binding domain 104 313 1.5E-21 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_23385 77b039b268d629da4ba03a778fa54beb 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 55 1.3E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_23385 77b039b268d629da4ba03a778fa54beb 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 45 1.3E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_23385 77b039b268d629da4ba03a778fa54beb 320 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 55 66 1.3E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_23385 77b039b268d629da4ba03a778fa54beb 320 SUPERFAMILY SSF46785 16 127 7.48E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_23385 77b039b268d629da4ba03a778fa54beb 320 Gene3D G3DSA:3.40.190.10 108 296 1.6E-28 T 14-10-2018 LH59_23385 77b039b268d629da4ba03a778fa54beb 320 SUPERFAMILY SSF53850 107 317 5.07E-22 T 14-10-2018 LH59_07360 5f6c17cb1144067157bbce65e82dc0cd 249 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 155 175 - T 14-10-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 LH59_07360 5f6c17cb1144067157bbce65e82dc0cd 249 PIRSF PIRSF000090 1 249 8.2E-87 T 14-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 LH59_07360 5f6c17cb1144067157bbce65e82dc0cd 249 SMART SM00893 23 211 1.1E-68 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 LH59_07360 5f6c17cb1144067157bbce65e82dc0cd 249 Gene3D G3DSA:3.40.50.620 1 248 1.3E-90 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LH59_07360 5f6c17cb1144067157bbce65e82dc0cd 249 SUPERFAMILY SSF52402 1 242 3.98E-87 T 14-10-2018 LH59_07360 5f6c17cb1144067157bbce65e82dc0cd 249 Pfam PF01012 Electron transfer flavoprotein domain 28 206 5.6E-47 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 LH59_09635 3a680256c9ee6b4015cc9c7708de3631 569 Pfam PF05524 PEP-utilising enzyme, N-terminal 3 125 2.9E-26 T 14-10-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 LH59_09635 3a680256c9ee6b4015cc9c7708de3631 569 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 254 543 1.7E-105 T 14-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 LH59_09635 3a680256c9ee6b4015cc9c7708de3631 569 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 1 554 9.4E-155 T 14-10-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 LH59_09635 3a680256c9ee6b4015cc9c7708de3631 569 PIRSF PIRSF000732 1 564 1.9E-199 T 14-10-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 LH59_09635 3a680256c9ee6b4015cc9c7708de3631 569 Pfam PF00391 PEP-utilising enzyme, mobile domain 156 228 1.2E-21 T 14-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 LH59_09635 3a680256c9ee6b4015cc9c7708de3631 569 SUPERFAMILY SSF47831 23 142 4.71E-30 T 14-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 LH59_09635 3a680256c9ee6b4015cc9c7708de3631 569 Gene3D G3DSA:1.10.274.10 20 145 4.6E-69 T 14-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 LH59_09635 3a680256c9ee6b4015cc9c7708de3631 569 Gene3D G3DSA:3.50.30.10 4 236 4.6E-69 T 14-10-2018 LH59_09635 3a680256c9ee6b4015cc9c7708de3631 569 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 187 198 - T 14-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 LH59_09635 3a680256c9ee6b4015cc9c7708de3631 569 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 466 481 1.3E-25 T 14-10-2018 LH59_09635 3a680256c9ee6b4015cc9c7708de3631 569 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 502 514 1.3E-25 T 14-10-2018 LH59_09635 3a680256c9ee6b4015cc9c7708de3631 569 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 296 315 1.3E-25 T 14-10-2018 LH59_09635 3a680256c9ee6b4015cc9c7708de3631 569 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 449 464 1.3E-25 T 14-10-2018 LH59_09635 3a680256c9ee6b4015cc9c7708de3631 569 SUPERFAMILY SSF52009 124 249 6.8E-32 T 14-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 LH59_09635 3a680256c9ee6b4015cc9c7708de3631 569 Gene3D G3DSA:3.20.20.60 237 564 3.9E-110 T 14-10-2018 LH59_09635 3a680256c9ee6b4015cc9c7708de3631 569 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 449 467 - T 14-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 LH59_09635 3a680256c9ee6b4015cc9c7708de3631 569 SUPERFAMILY SSF51621 253 547 6.81E-100 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 LH59_10700 2b8813172b4c5601b9cb09e0e91dc766 535 Pfam PF13193 AMP-binding enzyme C-terminal domain 438 510 1.3E-5 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain LH59_10700 2b8813172b4c5601b9cb09e0e91dc766 535 Gene3D G3DSA:3.40.50.980 6 157 9.5E-36 T 14-10-2018 LH59_10700 2b8813172b4c5601b9cb09e0e91dc766 535 Pfam PF00501 AMP-binding enzyme 15 413 2.7E-63 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 LH59_10700 2b8813172b4c5601b9cb09e0e91dc766 535 SUPERFAMILY SSF56801 8 528 2.22E-105 T 14-10-2018 LH59_10700 2b8813172b4c5601b9cb09e0e91dc766 535 Gene3D G3DSA:2.30.38.10 349 422 3.6E-17 T 14-10-2018 LH59_10700 2b8813172b4c5601b9cb09e0e91dc766 535 Gene3D G3DSA:3.30.300.30 424 529 1.6E-16 T 14-10-2018 LH59_10700 2b8813172b4c5601b9cb09e0e91dc766 535 Gene3D G3DSA:3.40.50.980 174 337 3.8E-22 T 14-10-2018 LH59_26315 bdce852937972223f6ce9a23c6b262cb 378 PIRSF PIRSF000729 10 378 1.1E-127 T 14-10-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 LH59_26315 bdce852937972223f6ce9a23c6b262cb 378 TIGRFAM TIGR01027 proB: glutamate 5-kinase 15 376 2.4E-129 T 14-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 LH59_26315 bdce852937972223f6ce9a23c6b262cb 378 ProSitePatterns PS00902 Glutamate 5-kinase signature. 217 234 - T 14-10-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 LH59_26315 bdce852937972223f6ce9a23c6b262cb 378 Gene3D G3DSA:2.30.130.10 276 378 4.6E-33 T 14-10-2018 IPR036974 PUA domain superfamily GO:0003723 LH59_26315 bdce852937972223f6ce9a23c6b262cb 378 Gene3D G3DSA:3.40.1160.10 7 268 3.1E-91 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily LH59_26315 bdce852937972223f6ce9a23c6b262cb 378 SUPERFAMILY SSF88697 286 377 2.87E-25 T 14-10-2018 IPR015947 PUA-like superfamily LH59_26315 bdce852937972223f6ce9a23c6b262cb 378 Pfam PF01472 PUA domain 287 361 4.8E-23 T 14-10-2018 IPR002478 PUA domain GO:0003723 LH59_26315 bdce852937972223f6ce9a23c6b262cb 378 PRINTS PR00474 Glutamate 5-kinase family signature 158 185 3.6E-51 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 LH59_26315 bdce852937972223f6ce9a23c6b262cb 378 PRINTS PR00474 Glutamate 5-kinase family signature 126 147 3.6E-51 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 LH59_26315 bdce852937972223f6ce9a23c6b262cb 378 PRINTS PR00474 Glutamate 5-kinase family signature 219 239 3.6E-51 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 LH59_26315 bdce852937972223f6ce9a23c6b262cb 378 PRINTS PR00474 Glutamate 5-kinase family signature 52 66 3.6E-51 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 LH59_26315 bdce852937972223f6ce9a23c6b262cb 378 PRINTS PR00474 Glutamate 5-kinase family signature 86 114 3.6E-51 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 LH59_26315 bdce852937972223f6ce9a23c6b262cb 378 SMART SM00359 287 370 9.2E-17 T 14-10-2018 IPR002478 PUA domain GO:0003723 LH59_26315 bdce852937972223f6ce9a23c6b262cb 378 Hamap MF_00456 Glutamate 5-kinase [proB]. 15 276 36.245 T 14-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 LH59_26315 bdce852937972223f6ce9a23c6b262cb 378 Pfam PF00696 Amino acid kinase family 16 244 2.2E-42 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 LH59_26315 bdce852937972223f6ce9a23c6b262cb 378 SUPERFAMILY SSF53633 15 264 4.45E-69 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily LH59_04210 55ccc781c89d312c30f6742330cd1b7f 329 Pfam PF04773 FecR protein 116 188 8.4E-8 T 14-10-2018 IPR006860 FecR protein LH59_04210 55ccc781c89d312c30f6742330cd1b7f 329 Pfam PF16220 Domain of unknown function (DUF4880) 11 52 3.5E-12 T 14-10-2018 IPR032623 FecR, N-terminal LH59_04210 55ccc781c89d312c30f6742330cd1b7f 329 PIRSF PIRSF018266 1 324 3.3E-60 T 14-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component LH59_14960 87bd8e9a65ff813eb539af644de2809d 325 SUPERFAMILY SSF53850 113 287 6.36E-11 T 14-10-2018 LH59_14960 87bd8e9a65ff813eb539af644de2809d 325 Gene3D G3DSA:3.40.190.10 127 250 8.5E-114 T 14-10-2018 LH59_14960 87bd8e9a65ff813eb539af644de2809d 325 Gene3D G3DSA:3.40.190.150 29 315 8.5E-114 T 14-10-2018 LH59_14960 87bd8e9a65ff813eb539af644de2809d 325 PIRSF PIRSF017082 1 323 1.7E-80 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_14960 87bd8e9a65ff813eb539af644de2809d 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 317 2.5E-82 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_10420 2b82a0d41d5f8a9c40f87d52073892aa 70 TIGRFAM TIGR03141 cytochro_ccmD: heme exporter protein CcmD 11 55 2.1E-11 T 14-10-2018 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 LH59_10420 2b82a0d41d5f8a9c40f87d52073892aa 70 Pfam PF04995 Heme exporter protein D (CcmD) 17 55 6.2E-9 T 14-10-2018 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 LH59_13670 e91a2bfc04ef4f349ee93510c9543727 332 PIRSF PIRSF001439 1 322 5.7E-59 T 14-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 LH59_13670 e91a2bfc04ef4f349ee93510c9543727 332 Gene3D G3DSA:3.40.50.720 121 294 2.5E-69 T 14-10-2018 LH59_13670 e91a2bfc04ef4f349ee93510c9543727 332 SUPERFAMILY SSF51735 5 320 1.1E-65 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_13670 e91a2bfc04ef4f349ee93510c9543727 332 Gene3D G3DSA:3.30.1780.10 8 316 2.5E-69 T 14-10-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 LH59_13670 e91a2bfc04ef4f349ee93510c9543727 332 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 83 312 2.4E-42 T 14-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 LH59_17335 0ff95b8cf13c2d57b77471cea0ce917d 319 Gene3D G3DSA:3.10.450.50 198 317 2.7E-43 T 14-10-2018 LH59_17335 0ff95b8cf13c2d57b77471cea0ce917d 319 SUPERFAMILY SSF109604 8 167 3.19E-33 T 14-10-2018 LH59_17335 0ff95b8cf13c2d57b77471cea0ce917d 319 Pfam PF13023 HD domain 16 169 2.6E-36 T 14-10-2018 IPR006674 HD domain LH59_17335 0ff95b8cf13c2d57b77471cea0ce917d 319 Gene3D G3DSA:1.10.3210.10 1 192 1.3E-39 T 14-10-2018 LH59_17335 0ff95b8cf13c2d57b77471cea0ce917d 319 SUPERFAMILY SSF54427 199 310 4.99E-32 T 14-10-2018 IPR032710 NTF2-like domain superfamily LH59_17335 0ff95b8cf13c2d57b77471cea0ce917d 319 Pfam PF12680 SnoaL-like domain 205 304 1.6E-15 T 14-10-2018 IPR037401 SnoaL-like domain LH59_17335 0ff95b8cf13c2d57b77471cea0ce917d 319 SMART SM00471 32 149 0.0048 T 14-10-2018 IPR003607 HD/PDEase domain LH59_25310 c33a989e648a5f3cac8f2e1f69b897b0 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 324 1.8E-89 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_25310 c33a989e648a5f3cac8f2e1f69b897b0 328 SUPERFAMILY SSF53850 92 287 4.89E-19 T 14-10-2018 LH59_25310 c33a989e648a5f3cac8f2e1f69b897b0 328 Gene3D G3DSA:3.40.190.150 32 318 5.6E-116 T 14-10-2018 LH59_25310 c33a989e648a5f3cac8f2e1f69b897b0 328 Gene3D G3DSA:3.40.190.10 130 253 5.6E-116 T 14-10-2018 LH59_25310 c33a989e648a5f3cac8f2e1f69b897b0 328 PIRSF PIRSF017082 1 328 2.2E-92 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_10740 b821617db4cb5d07f215ebb176884f47 209 PIRSF PIRSF006324 1 209 6.1E-50 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 LH59_10740 b821617db4cb5d07f215ebb176884f47 209 Pfam PF01810 LysE type translocator 13 208 1.3E-34 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 LH59_16075 aa37c55dc0e06c386fa35a3f3af97230 713 Gene3D G3DSA:2.40.170.20 167 702 9.8E-58 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_16075 aa37c55dc0e06c386fa35a3f3af97230 713 Gene3D G3DSA:2.170.130.10 42 163 1.3E-25 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily LH59_16075 aa37c55dc0e06c386fa35a3f3af97230 713 Pfam PF00593 TonB dependent receptor 235 686 1.0E-30 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_16075 aa37c55dc0e06c386fa35a3f3af97230 713 Pfam PF07715 TonB-dependent Receptor Plug Domain 56 157 3.5E-22 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_16075 aa37c55dc0e06c386fa35a3f3af97230 713 SUPERFAMILY SSF56935 34 695 2.36E-94 T 14-10-2018 LH59_11020 3a69831aa4c3bd6673b832238f3d0e49 443 Pfam PF00924 Mechanosensitive ion channel 146 397 3.7E-43 T 14-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 LH59_11020 3a69831aa4c3bd6673b832238f3d0e49 443 SUPERFAMILY SSF50182 185 252 1.08E-10 T 14-10-2018 IPR010920 LSM domain superfamily LH59_06020 4f5805d0a100811ceaf6c2f80c77ad94 1039 SUPERFAMILY SSF82693 553 650 1.1E-15 T 14-10-2018 LH59_06020 4f5805d0a100811ceaf6c2f80c77ad94 1039 Gene3D G3DSA:3.30.70.1430 40 794 1.5E-283 T 14-10-2018 LH59_06020 4f5805d0a100811ceaf6c2f80c77ad94 1039 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 7.2E-69 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_06020 4f5805d0a100811ceaf6c2f80c77ad94 1039 PRINTS PR00702 Acriflavin resistance protein family signature 329 352 7.2E-69 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_06020 4f5805d0a100811ceaf6c2f80c77ad94 1039 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 7.2E-69 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_06020 4f5805d0a100811ceaf6c2f80c77ad94 1039 PRINTS PR00702 Acriflavin resistance protein family signature 540 557 7.2E-69 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_06020 4f5805d0a100811ceaf6c2f80c77ad94 1039 PRINTS PR00702 Acriflavin resistance protein family signature 384 408 7.2E-69 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_06020 4f5805d0a100811ceaf6c2f80c77ad94 1039 PRINTS PR00702 Acriflavin resistance protein family signature 437 460 7.2E-69 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_06020 4f5805d0a100811ceaf6c2f80c77ad94 1039 PRINTS PR00702 Acriflavin resistance protein family signature 462 485 7.2E-69 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_06020 4f5805d0a100811ceaf6c2f80c77ad94 1039 PRINTS PR00702 Acriflavin resistance protein family signature 356 377 7.2E-69 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_06020 4f5805d0a100811ceaf6c2f80c77ad94 1039 SUPERFAMILY SSF82693 650 833 2.88E-23 T 14-10-2018 LH59_06020 4f5805d0a100811ceaf6c2f80c77ad94 1039 SUPERFAMILY SSF82714 699 786 2.75E-19 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_06020 4f5805d0a100811ceaf6c2f80c77ad94 1039 Gene3D G3DSA:3.30.70.1430 555 647 1.5E-283 T 14-10-2018 LH59_06020 4f5805d0a100811ceaf6c2f80c77ad94 1039 SUPERFAMILY SSF82714 183 264 9.02E-16 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_06020 4f5805d0a100811ceaf6c2f80c77ad94 1039 Gene3D G3DSA:3.30.70.1440 648 842 1.5E-283 T 14-10-2018 LH59_06020 4f5805d0a100811ceaf6c2f80c77ad94 1039 Gene3D G3DSA:3.30.2090.10 178 268 1.5E-283 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_06020 4f5805d0a100811ceaf6c2f80c77ad94 1039 SUPERFAMILY SSF82693 43 130 1.03E-23 T 14-10-2018 LH59_06020 4f5805d0a100811ceaf6c2f80c77ad94 1039 Pfam PF00873 AcrB/AcrD/AcrF family 4 1003 8.7E-262 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_06020 4f5805d0a100811ceaf6c2f80c77ad94 1039 SUPERFAMILY SSF82866 299 489 4.71E-47 T 14-10-2018 LH59_06020 4f5805d0a100811ceaf6c2f80c77ad94 1039 Gene3D G3DSA:1.20.1640.10 10 500 1.5E-283 T 14-10-2018 LH59_06020 4f5805d0a100811ceaf6c2f80c77ad94 1039 SUPERFAMILY SSF82866 818 1004 9.55E-43 T 14-10-2018 LH59_06020 4f5805d0a100811ceaf6c2f80c77ad94 1039 Gene3D G3DSA:3.30.2090.10 698 786 1.5E-283 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_06020 4f5805d0a100811ceaf6c2f80c77ad94 1039 Gene3D G3DSA:1.20.1640.10 501 1000 1.5E-283 T 14-10-2018 LH59_06020 4f5805d0a100811ceaf6c2f80c77ad94 1039 SUPERFAMILY SSF82693 137 320 2.88E-17 T 14-10-2018 LH59_06020 4f5805d0a100811ceaf6c2f80c77ad94 1039 Gene3D G3DSA:3.30.70.1320 134 325 1.5E-283 T 14-10-2018 LH59_24700 13819fa22280c507386169e9db0aa429 643 Gene3D G3DSA:3.60.20.10 2 190 4.4E-55 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal LH59_24700 13819fa22280c507386169e9db0aa429 643 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 563 3.2E-135 T 14-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 LH59_24700 13819fa22280c507386169e9db0aa429 643 PIRSF PIRSF001589 1 641 1.6E-160 T 14-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 LH59_24700 13819fa22280c507386169e9db0aa429 643 Pfam PF00733 Asparagine synthase 256 627 4.3E-112 T 14-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 LH59_24700 13819fa22280c507386169e9db0aa429 643 SUPERFAMILY SSF56235 1 224 4.98E-59 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal LH59_24700 13819fa22280c507386169e9db0aa429 643 Pfam PF13537 Glutamine amidotransferase domain 47 169 1.5E-42 T 14-10-2018 IPR017932 Glutamine amidotransferase type 2 domain LH59_24700 13819fa22280c507386169e9db0aa429 643 SUPERFAMILY SSF52402 248 623 5.24E-91 T 14-10-2018 LH59_07630 b525a0af6cc36b47ee403f19a0e395d6 492 Gene3D G3DSA:3.30.1480.10 1 128 1.6E-41 T 14-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 LH59_07630 b525a0af6cc36b47ee403f19a0e395d6 492 SUPERFAMILY SSF54814 281 344 2.42E-14 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 LH59_07630 b525a0af6cc36b47ee403f19a0e395d6 492 SUPERFAMILY SSF50249 135 201 4.6E-15 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_07630 b525a0af6cc36b47ee403f19a0e395d6 492 Pfam PF08529 NusA N-terminal domain 4 127 3.7E-37 T 14-10-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 LH59_07630 b525a0af6cc36b47ee403f19a0e395d6 492 Gene3D G3DSA:3.30.300.20 280 347 2.5E-25 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta LH59_07630 b525a0af6cc36b47ee403f19a0e395d6 492 Gene3D G3DSA:1.10.150.20 430 488 3.0E-22 T 14-10-2018 LH59_07630 b525a0af6cc36b47ee403f19a0e395d6 492 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 5 343 9.2E-122 T 14-10-2018 IPR010213 Transcription termination factor NusA GO:0003723 LH59_07630 b525a0af6cc36b47ee403f19a0e395d6 492 Gene3D G3DSA:2.40.50.140 129 200 1.6E-19 T 14-10-2018 LH59_07630 b525a0af6cc36b47ee403f19a0e395d6 492 Pfam PF00575 S1 RNA binding domain 138 194 1.8E-5 T 14-10-2018 IPR003029 S1 domain GO:0003676 LH59_07630 b525a0af6cc36b47ee403f19a0e395d6 492 SUPERFAMILY SSF47794 428 489 9.89E-15 T 14-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 LH59_07630 b525a0af6cc36b47ee403f19a0e395d6 492 Pfam PF13184 NusA-like KH domain 232 299 6.7E-25 T 14-10-2018 IPR025249 KH domain, NusA-like GO:0003723 LH59_07630 b525a0af6cc36b47ee403f19a0e395d6 492 SUPERFAMILY SSF47794 359 418 6.91E-16 T 14-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 LH59_07630 b525a0af6cc36b47ee403f19a0e395d6 492 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 412 28.795 T 14-10-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 LH59_07630 b525a0af6cc36b47ee403f19a0e395d6 492 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 367 416 3.6E-18 T 14-10-2018 IPR010214 Transcription termination factor NusA, C-terminal duplication LH59_07630 b525a0af6cc36b47ee403f19a0e395d6 492 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 442 488 4.2E-15 T 14-10-2018 IPR010214 Transcription termination factor NusA, C-terminal duplication LH59_07630 b525a0af6cc36b47ee403f19a0e395d6 492 Gene3D G3DSA:1.10.150.20 356 423 1.4E-28 T 14-10-2018 LH59_07630 b525a0af6cc36b47ee403f19a0e395d6 492 SMART SM00316 136 202 2.7E-9 T 14-10-2018 IPR022967 RNA-binding domain, S1 LH59_07630 b525a0af6cc36b47ee403f19a0e395d6 492 SUPERFAMILY SSF54814 202 280 2.03E-28 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 LH59_07630 b525a0af6cc36b47ee403f19a0e395d6 492 Gene3D G3DSA:3.30.300.20 201 279 2.1E-30 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta LH59_07630 b525a0af6cc36b47ee403f19a0e395d6 492 Pfam PF14520 Helix-hairpin-helix domain 431 485 1.0E-9 T 14-10-2018 LH59_07630 b525a0af6cc36b47ee403f19a0e395d6 492 SUPERFAMILY SSF69705 1 129 4.32E-39 T 14-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 LH59_22195 d363777b0266698446542b5998d851e8 397 Gene3D G3DSA:1.20.140.10 245 397 3.8E-43 T 14-10-2018 LH59_22195 d363777b0266698446542b5998d851e8 397 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 349 368 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 LH59_22195 d363777b0266698446542b5998d851e8 397 SUPERFAMILY SSF47203 246 395 3.54E-43 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 LH59_22195 d363777b0266698446542b5998d851e8 397 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 20 132 7.5E-34 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 LH59_22195 d363777b0266698446542b5998d851e8 397 Gene3D G3DSA:1.10.540.10 2 134 5.5E-42 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 LH59_22195 d363777b0266698446542b5998d851e8 397 SUPERFAMILY SSF56645 7 243 2.49E-76 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 LH59_22195 d363777b0266698446542b5998d851e8 397 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 244 389 3.2E-29 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LH59_22195 d363777b0266698446542b5998d851e8 397 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 136 231 9.2E-21 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 LH59_22195 d363777b0266698446542b5998d851e8 397 Gene3D G3DSA:2.40.110.10 135 243 1.3E-36 T 14-10-2018 LH59_27690 f7f3238c16ee931f765862a4a736cd18 207 Gene3D G3DSA:3.40.50.300 1 205 3.7E-50 T 14-10-2018 LH59_27690 f7f3238c16ee931f765862a4a736cd18 207 Pfam PF01926 50S ribosome-binding GTPase 26 151 7.1E-18 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 LH59_27690 f7f3238c16ee931f765862a4a736cd18 207 SUPERFAMILY SSF52540 7 201 2.01E-34 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_27690 f7f3238c16ee931f765862a4a736cd18 207 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 7 197 6.4E-60 T 14-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 LH59_27690 f7f3238c16ee931f765862a4a736cd18 207 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 12 201 25.953 T 14-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 LH59_05330 bb55286be19d81097b02eb5b1d0cef2e 917 Gene3D G3DSA:3.30.830.10 38 259 1.8E-61 T 14-10-2018 LH59_05330 bb55286be19d81097b02eb5b1d0cef2e 917 SUPERFAMILY SSF63411 741 914 3.03E-29 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 LH59_05330 bb55286be19d81097b02eb5b1d0cef2e 917 SUPERFAMILY SSF63411 269 452 3.35E-25 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 LH59_05330 bb55286be19d81097b02eb5b1d0cef2e 917 Gene3D G3DSA:3.30.830.10 498 712 4.4E-24 T 14-10-2018 LH59_05330 bb55286be19d81097b02eb5b1d0cef2e 917 Pfam PF00675 Insulinase (Peptidase family M16) 53 199 1.6E-20 T 14-10-2018 IPR011765 Peptidase M16, N-terminal LH59_05330 bb55286be19d81097b02eb5b1d0cef2e 917 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 74 97 - T 14-10-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 LH59_05330 bb55286be19d81097b02eb5b1d0cef2e 917 SUPERFAMILY SSF63411 479 716 8.33E-27 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 LH59_05330 bb55286be19d81097b02eb5b1d0cef2e 917 SUPERFAMILY SSF63411 42 258 3.5E-52 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 LH59_05330 bb55286be19d81097b02eb5b1d0cef2e 917 Gene3D G3DSA:3.30.830.10 727 916 4.1E-38 T 14-10-2018 LH59_05330 bb55286be19d81097b02eb5b1d0cef2e 917 Pfam PF05193 Peptidase M16 inactive domain 666 845 1.3E-25 T 14-10-2018 IPR007863 Peptidase M16, C-terminal LH59_05330 bb55286be19d81097b02eb5b1d0cef2e 917 Pfam PF05193 Peptidase M16 inactive domain 208 382 6.5E-28 T 14-10-2018 IPR007863 Peptidase M16, C-terminal LH59_05330 bb55286be19d81097b02eb5b1d0cef2e 917 Gene3D G3DSA:3.30.830.10 260 467 1.9E-50 T 14-10-2018 LH59_24070 007b23354da592ba90068edca3e08de0 815 Pfam PF00271 Helicase conserved C-terminal domain 255 351 7.3E-13 T 14-10-2018 IPR001650 Helicase, C-terminal LH59_24070 007b23354da592ba90068edca3e08de0 815 Gene3D G3DSA:3.40.50.300 242 387 4.6E-22 T 14-10-2018 LH59_24070 007b23354da592ba90068edca3e08de0 815 Pfam PF00270 DEAD/DEAH box helicase 22 194 4.6E-23 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 LH59_24070 007b23354da592ba90068edca3e08de0 815 SMART SM00487 16 223 2.6E-23 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain LH59_24070 007b23354da592ba90068edca3e08de0 815 SMART SM00490 273 355 2.0E-17 T 14-10-2018 IPR001650 Helicase, C-terminal LH59_24070 007b23354da592ba90068edca3e08de0 815 SUPERFAMILY SSF52540 30 362 1.35E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_24070 007b23354da592ba90068edca3e08de0 815 Gene3D G3DSA:3.40.50.300 11 207 5.7E-42 T 14-10-2018 LH59_24070 007b23354da592ba90068edca3e08de0 815 Pfam PF08494 DEAD/H associated 592 779 8.8E-43 T 14-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 LH59_24070 007b23354da592ba90068edca3e08de0 815 TIGRFAM TIGR04121 DEXH_lig_assoc: DEXH box helicase, DNA ligase-associated 9 808 0.0 T 14-10-2018 IPR026362 DEXH box helicase, DNA ligase-associated LH59_24070 007b23354da592ba90068edca3e08de0 815 PIRSF PIRSF037307 2 811 2.3E-133 T 14-10-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 LH59_04985 8c28449c0830136f2082c8eac02b037d 609 Gene3D G3DSA:1.10.150.80 538 606 3.3E-23 T 14-10-2018 LH59_04985 8c28449c0830136f2082c8eac02b037d 609 Gene3D G3DSA:1.10.10.10 335 522 5.6E-48 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_04985 8c28449c0830136f2082c8eac02b037d 609 Pfam PF09382 RQC domain 400 515 4.8E-38 T 14-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 LH59_04985 8c28449c0830136f2082c8eac02b037d 609 SUPERFAMILY SSF47819 535 606 2.07E-21 T 14-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 LH59_04985 8c28449c0830136f2082c8eac02b037d 609 Gene3D G3DSA:3.40.50.300 1 201 1.9E-80 T 14-10-2018 LH59_04985 8c28449c0830136f2082c8eac02b037d 609 Gene3D G3DSA:3.40.50.300 202 334 1.1E-38 T 14-10-2018 LH59_04985 8c28449c0830136f2082c8eac02b037d 609 Pfam PF00270 DEAD/DEAH box helicase 22 180 3.5E-17 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 LH59_04985 8c28449c0830136f2082c8eac02b037d 609 SUPERFAMILY SSF52540 201 452 6.69E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_04985 8c28449c0830136f2082c8eac02b037d 609 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 9 604 1.6E-241 T 14-10-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 LH59_04985 8c28449c0830136f2082c8eac02b037d 609 SMART SM00487 15 211 5.0E-29 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain LH59_04985 8c28449c0830136f2082c8eac02b037d 609 SMART SM00490 244 325 6.4E-25 T 14-10-2018 IPR001650 Helicase, C-terminal LH59_04985 8c28449c0830136f2082c8eac02b037d 609 SUPERFAMILY SSF52540 5 190 4.15E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_04985 8c28449c0830136f2082c8eac02b037d 609 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 9 461 6.7E-151 T 14-10-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 LH59_04985 8c28449c0830136f2082c8eac02b037d 609 SMART SM00956 405 512 5.2E-49 T 14-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 LH59_04985 8c28449c0830136f2082c8eac02b037d 609 Pfam PF00570 HRDC domain 539 602 4.5E-22 T 14-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 LH59_04985 8c28449c0830136f2082c8eac02b037d 609 Pfam PF00271 Helicase conserved C-terminal domain 218 324 5.1E-15 T 14-10-2018 IPR001650 Helicase, C-terminal LH59_04985 8c28449c0830136f2082c8eac02b037d 609 SMART SM00341 534 607 3.6E-10 T 14-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 LH59_04985 8c28449c0830136f2082c8eac02b037d 609 Pfam PF16124 RecQ zinc-binding 337 398 7.6E-17 T 14-10-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain LH59_06885 38309073a8826cc6d2b4b8ed2cec86f3 259 SMART SM00866 111 253 6.5E-38 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LH59_06885 38309073a8826cc6d2b4b8ed2cec86f3 259 SUPERFAMILY SSF46785 25 102 7.66E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_06885 38309073a8826cc6d2b4b8ed2cec86f3 259 Pfam PF07702 UTRA domain 115 253 6.7E-36 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LH59_06885 38309073a8826cc6d2b4b8ed2cec86f3 259 Gene3D G3DSA:1.10.10.10 23 91 1.6E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_06885 38309073a8826cc6d2b4b8ed2cec86f3 259 SUPERFAMILY SSF64288 79 257 9.89E-43 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily LH59_06885 38309073a8826cc6d2b4b8ed2cec86f3 259 Pfam PF00392 Bacterial regulatory proteins, gntR family 27 90 1.6E-19 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_06885 38309073a8826cc6d2b4b8ed2cec86f3 259 SMART SM00345 31 90 1.1E-20 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_06885 38309073a8826cc6d2b4b8ed2cec86f3 259 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 64 80 1.9E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_06885 38309073a8826cc6d2b4b8ed2cec86f3 259 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 64 1.9E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_06885 38309073a8826cc6d2b4b8ed2cec86f3 259 Gene3D G3DSA:3.40.1410.10 98 258 1.3E-60 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily LH59_00565 e2c2b1f0037b217b226a1d3b34018e2b 393 Gene3D G3DSA:3.40.47.10 127 390 1.8E-141 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_00565 e2c2b1f0037b217b226a1d3b34018e2b 393 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 391 2.2E-126 T 14-10-2018 IPR002155 Thiolase GO:0016747 LH59_00565 e2c2b1f0037b217b226a1d3b34018e2b 393 PIRSF PIRSF000429 1 393 5.2E-114 T 14-10-2018 IPR002155 Thiolase GO:0016747 LH59_00565 e2c2b1f0037b217b226a1d3b34018e2b 393 Pfam PF02803 Thiolase, C-terminal domain 271 391 2.6E-41 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 LH59_00565 e2c2b1f0037b217b226a1d3b34018e2b 393 Pfam PF00108 Thiolase, N-terminal domain 5 262 3.1E-88 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 LH59_00565 e2c2b1f0037b217b226a1d3b34018e2b 393 SUPERFAMILY SSF53901 5 270 1.51E-79 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_00565 e2c2b1f0037b217b226a1d3b34018e2b 393 Gene3D G3DSA:3.40.47.10 7 276 1.8E-141 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_00565 e2c2b1f0037b217b226a1d3b34018e2b 393 SUPERFAMILY SSF53901 271 392 7.52E-40 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_00565 e2c2b1f0037b217b226a1d3b34018e2b 393 ProSitePatterns PS00099 Thiolases active site. 374 387 - T 14-10-2018 IPR020610 Thiolase, active site GO:0016747 LH59_08875 cac858d4dacb362bcc20bda147bca35a 243 Gene3D G3DSA:3.30.70.980 130 205 6.2E-52 T 14-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_08875 cac858d4dacb362bcc20bda147bca35a 243 SUPERFAMILY SSF75625 3 240 1.11E-94 T 14-10-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_08875 cac858d4dacb362bcc20bda147bca35a 243 Pfam PF01709 Transcriptional regulator 5 236 7.0E-96 T 14-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_08875 cac858d4dacb362bcc20bda147bca35a 243 Gene3D G3DSA:3.30.70.980 85 235 6.2E-52 T 14-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_08875 cac858d4dacb362bcc20bda147bca35a 243 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 239 34.54 T 14-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_08875 cac858d4dacb362bcc20bda147bca35a 243 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 235 3.6E-92 T 14-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_08875 cac858d4dacb362bcc20bda147bca35a 243 Gene3D G3DSA:1.10.10.200 1 81 4.1E-35 T 14-10-2018 IPR017856 Integrase-like, N-terminal LH59_22340 4572f09cce7949756a61416dd5cd9249 293 ProSitePatterns PS01057 SAICAR synthetase signature 1. 106 120 - T 14-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 LH59_22340 4572f09cce7949756a61416dd5cd9249 293 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 13 293 25.874 T 14-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 LH59_22340 4572f09cce7949756a61416dd5cd9249 293 Pfam PF01259 SAICAR synthetase 16 268 2.5E-102 T 14-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 LH59_22340 4572f09cce7949756a61416dd5cd9249 293 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 16 292 9.3E-83 T 14-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 LH59_22340 4572f09cce7949756a61416dd5cd9249 293 SUPERFAMILY SSF56104 6 291 9.81E-103 T 14-10-2018 LH59_22340 4572f09cce7949756a61416dd5cd9249 293 ProSitePatterns PS01058 SAICAR synthetase signature 2. 205 213 - T 14-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 LH59_22340 4572f09cce7949756a61416dd5cd9249 293 Gene3D G3DSA:3.30.200.20 4 104 1.1E-30 T 14-10-2018 LH59_22340 4572f09cce7949756a61416dd5cd9249 293 Gene3D G3DSA:3.30.470.20 106 249 2.0E-57 T 14-10-2018 LH59_17180 776aef4ae7e98f7b99a59067406d6bf7 107 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 103 1.8E-23 T 14-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 LH59_17180 776aef4ae7e98f7b99a59067406d6bf7 107 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 88 105 - T 14-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 LH59_17180 776aef4ae7e98f7b99a59067406d6bf7 107 SUPERFAMILY SSF89360 1 96 3.92E-31 T 14-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 LH59_17180 776aef4ae7e98f7b99a59067406d6bf7 107 TIGRFAM TIGR02011 IscA: iron-sulfur cluster assembly protein IscA 3 107 1.3E-51 T 14-10-2018 IPR011302 Iron-binding protein IscA, proteobacteria GO:0005506|GO:0051536|GO:0097428 LH59_17180 776aef4ae7e98f7b99a59067406d6bf7 107 Gene3D G3DSA:2.60.300.12 2 107 1.4E-37 T 14-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 LH59_17180 776aef4ae7e98f7b99a59067406d6bf7 107 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 3 107 4.7E-36 T 14-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 LH59_11575 a25c52c6b897b04c72ed575b6ab032f3 245 Pfam PF09339 IclR helix-turn-helix domain 7 54 2.1E-7 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_11575 a25c52c6b897b04c72ed575b6ab032f3 245 Gene3D G3DSA:1.10.10.10 1 76 2.0E-11 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_11575 a25c52c6b897b04c72ed575b6ab032f3 245 Gene3D G3DSA:3.30.450.40 79 245 1.6E-33 T 14-10-2018 IPR029016 GAF-like domain superfamily LH59_11575 a25c52c6b897b04c72ed575b6ab032f3 245 Pfam PF01614 Bacterial transcriptional regulator 128 237 2.6E-17 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal LH59_11575 a25c52c6b897b04c72ed575b6ab032f3 245 SUPERFAMILY SSF55781 77 243 4.19E-35 T 14-10-2018 LH59_11575 a25c52c6b897b04c72ed575b6ab032f3 245 SUPERFAMILY SSF46785 3 75 2.02E-10 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_06720 d7de42aa212131b5bf8ff0467b597001 149 Gene3D G3DSA:3.10.129.10 9 144 1.4E-34 T 14-10-2018 LH59_06720 d7de42aa212131b5bf8ff0467b597001 149 Pfam PF13279 Thioesterase-like superfamily 24 141 3.2E-17 T 14-10-2018 LH59_06720 d7de42aa212131b5bf8ff0467b597001 149 SUPERFAMILY SSF54637 16 143 1.43E-30 T 14-10-2018 IPR029069 HotDog domain superfamily LH59_10255 48b2f84c48a66ca9d951d1d57f5ad39c 618 Pfam PF17297 Phosphoenolpyruvate carboxykinase N-terminal domain 25 245 5.1E-104 T 14-10-2018 IPR035078 Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 LH59_10255 48b2f84c48a66ca9d951d1d57f5ad39c 618 SUPERFAMILY SSF68923 12 248 6.8E-102 T 14-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 LH59_10255 48b2f84c48a66ca9d951d1d57f5ad39c 618 PIRSF PIRSF001348 7 618 1.6E-279 T 14-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 LH59_10255 48b2f84c48a66ca9d951d1d57f5ad39c 618 Gene3D G3DSA:3.90.228.20 249 607 5.1E-257 T 14-10-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 LH59_10255 48b2f84c48a66ca9d951d1d57f5ad39c 618 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 14 617 51.223 T 14-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 LH59_10255 48b2f84c48a66ca9d951d1d57f5ad39c 618 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 273 281 - T 14-10-2018 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 LH59_10255 48b2f84c48a66ca9d951d1d57f5ad39c 618 Gene3D G3DSA:2.170.8.10 61 408 5.1E-257 T 14-10-2018 LH59_10255 48b2f84c48a66ca9d951d1d57f5ad39c 618 Gene3D G3DSA:3.40.449.10 25 248 5.1E-257 T 14-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 LH59_10255 48b2f84c48a66ca9d951d1d57f5ad39c 618 SUPERFAMILY SSF53795 249 616 8.47E-154 T 14-10-2018 LH59_10255 48b2f84c48a66ca9d951d1d57f5ad39c 618 Pfam PF00821 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain 249 616 5.4E-166 T 14-10-2018 IPR035077 Phosphoenolpyruvate carboxykinase, GTP-utilising, C-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 LH59_01380 f84ace1f3d98030831010574e0eab12e 1061 SUPERFAMILY SSF82714 193 275 1.31E-18 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_01380 f84ace1f3d98030831010574e0eab12e 1061 Gene3D G3DSA:3.30.2090.10 189 280 0.0 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_01380 f84ace1f3d98030831010574e0eab12e 1061 Gene3D G3DSA:3.30.70.1430 42 829 0.0 T 14-10-2018 LH59_01380 f84ace1f3d98030831010574e0eab12e 1061 SUPERFAMILY SSF82693 573 668 1.83E-7 T 14-10-2018 LH59_01380 f84ace1f3d98030831010574e0eab12e 1061 Gene3D G3DSA:3.30.2090.10 727 821 0.0 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_01380 f84ace1f3d98030831010574e0eab12e 1061 Gene3D G3DSA:3.30.70.1320 135 333 0.0 T 14-10-2018 LH59_01380 f84ace1f3d98030831010574e0eab12e 1061 Gene3D G3DSA:1.20.1640.10 515 1034 0.0 T 14-10-2018 LH59_01380 f84ace1f3d98030831010574e0eab12e 1061 SUPERFAMILY SSF82714 726 816 1.16E-16 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_01380 f84ace1f3d98030831010574e0eab12e 1061 Gene3D G3DSA:1.20.1640.10 15 514 0.0 T 14-10-2018 LH59_01380 f84ace1f3d98030831010574e0eab12e 1061 Gene3D G3DSA:3.30.70.1440 676 879 0.0 T 14-10-2018 LH59_01380 f84ace1f3d98030831010574e0eab12e 1061 Gene3D G3DSA:3.30.70.1430 570 675 0.0 T 14-10-2018 LH59_01380 f84ace1f3d98030831010574e0eab12e 1061 SUPERFAMILY SSF82866 299 506 1.7E-36 T 14-10-2018 LH59_01380 f84ace1f3d98030831010574e0eab12e 1061 PRINTS PR00702 Acriflavin resistance protein family signature 480 503 1.8E-20 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_01380 f84ace1f3d98030831010574e0eab12e 1061 PRINTS PR00702 Acriflavin resistance protein family signature 366 387 1.8E-20 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_01380 f84ace1f3d98030831010574e0eab12e 1061 PRINTS PR00702 Acriflavin resistance protein family signature 339 362 1.8E-20 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_01380 f84ace1f3d98030831010574e0eab12e 1061 PRINTS PR00702 Acriflavin resistance protein family signature 553 570 1.8E-20 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_01380 f84ace1f3d98030831010574e0eab12e 1061 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 1.8E-20 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_01380 f84ace1f3d98030831010574e0eab12e 1061 SUPERFAMILY SSF82693 42 128 2.88E-22 T 14-10-2018 LH59_01380 f84ace1f3d98030831010574e0eab12e 1061 Pfam PF00873 AcrB/AcrD/AcrF family 6 1038 0.0 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_01380 f84ace1f3d98030831010574e0eab12e 1061 SUPERFAMILY SSF82866 815 1040 7.19E-57 T 14-10-2018 LH59_01380 f84ace1f3d98030831010574e0eab12e 1061 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 1 1047 0.0 T 14-10-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 LH59_01380 f84ace1f3d98030831010574e0eab12e 1061 SUPERFAMILY SSF82693 155 333 2.09E-19 T 14-10-2018 LH59_04290 fcc1676da11226e7efa765bbd2100a96 214 SUPERFAMILY SSF46689 4 84 1.08E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_04290 fcc1676da11226e7efa765bbd2100a96 214 SUPERFAMILY SSF48498 82 195 1.78E-26 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily LH59_04290 fcc1676da11226e7efa765bbd2100a96 214 Gene3D G3DSA:1.10.357.10 71 199 8.0E-31 T 14-10-2018 LH59_04290 fcc1676da11226e7efa765bbd2100a96 214 ProSitePatterns PS01081 TetR-type HTH domain signature. 27 57 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site LH59_04290 fcc1676da11226e7efa765bbd2100a96 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 1.4E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_04290 fcc1676da11226e7efa765bbd2100a96 214 Gene3D G3DSA:1.10.10.60 1 69 3.8E-29 T 14-10-2018 LH59_04410 981e9de9c8ca0642cbd89c7d5a7b726b 131 TIGRFAM TIGR00068 glyox_I: lactoylglutathione lyase 2 127 4.1E-67 T 14-10-2018 IPR004361 Glyoxalase I GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 LH59_04410 981e9de9c8ca0642cbd89c7d5a7b726b 131 SUPERFAMILY SSF54593 1 128 1.34E-38 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_04410 981e9de9c8ca0642cbd89c7d5a7b726b 131 ProSitePatterns PS00934 Glyoxalase I signature 1. 5 26 - T 14-10-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 LH59_04410 981e9de9c8ca0642cbd89c7d5a7b726b 131 Gene3D G3DSA:3.10.180.10 1 130 6.4E-50 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_04410 981e9de9c8ca0642cbd89c7d5a7b726b 131 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3 123 6.4E-25 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain LH59_04410 981e9de9c8ca0642cbd89c7d5a7b726b 131 ProSitePatterns PS00935 Glyoxalase I signature 2. 69 81 - T 14-10-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 LH59_05880 b2384290b3eff8ddd6395264302d7609 246 SUPERFAMILY SSF51735 4 245 2.79E-66 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_05880 b2384290b3eff8ddd6395264302d7609 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 243 3.9E-52 T 14-10-2018 LH59_05880 b2384290b3eff8ddd6395264302d7609 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LH59_05880 b2384290b3eff8ddd6395264302d7609 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 3.6E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_05880 b2384290b3eff8ddd6395264302d7609 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 3.6E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_05880 b2384290b3eff8ddd6395264302d7609 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 3.6E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_05880 b2384290b3eff8ddd6395264302d7609 246 Gene3D G3DSA:3.40.50.720 1 245 9.8E-71 T 14-10-2018 LH59_05880 b2384290b3eff8ddd6395264302d7609 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 2.9E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_05880 b2384290b3eff8ddd6395264302d7609 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 2.9E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_05880 b2384290b3eff8ddd6395264302d7609 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 2.9E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_05880 b2384290b3eff8ddd6395264302d7609 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 2.9E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_05880 b2384290b3eff8ddd6395264302d7609 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 2.9E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_05880 b2384290b3eff8ddd6395264302d7609 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 2.9E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_05880 b2384290b3eff8ddd6395264302d7609 246 TIGRFAM TIGR01829 AcAcCoA_reduct: acetoacetyl-CoA reductase 4 245 6.5E-91 T 14-10-2018 IPR011283 Acetoacetyl-CoA reductase GO:0005737|GO:0018454|GO:0042619|GO:0055114 KEGG: 00630+1.1.1.36|KEGG: 00650+1.1.1.36|MetaCyc: PWY-5676|MetaCyc: PWY-5741|MetaCyc: PWY-7216|MetaCyc: PWY-7948 LH59_05880 b2384290b3eff8ddd6395264302d7609 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 189 0.0025 T 14-10-2018 LH59_07400 0379f61e6af0b2901958fa04b6d8a43a 296 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 28 284 6.3E-97 T 14-10-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 LH59_07400 0379f61e6af0b2901958fa04b6d8a43a 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 290 2.0E-27 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_07400 0379f61e6af0b2901958fa04b6d8a43a 296 SUPERFAMILY SSF161098 33 283 1.5E-54 T 14-10-2018 IPR035906 MetI-like superfamily LH59_07400 0379f61e6af0b2901958fa04b6d8a43a 296 Gene3D G3DSA:1.10.3720.10 30 290 1.4E-69 T 14-10-2018 IPR035906 MetI-like superfamily LH59_07400 0379f61e6af0b2901958fa04b6d8a43a 296 TIGRFAM TIGR02139 permease_CysT: sulfate ABC transporter, permease protein CysT 25 289 2.4E-127 T 14-10-2018 IPR011865 Sulphate ABC transporter, permease protein CysT GO:0008272|GO:0015116|GO:0016021 LH59_15340 ba2bfd638731b813bb8fa902c8bc6559 164 Pfam PF13302 Acetyltransferase (GNAT) domain 7 142 2.5E-31 T 14-10-2018 IPR000182 GNAT domain LH59_15340 ba2bfd638731b813bb8fa902c8bc6559 164 SUPERFAMILY SSF55729 5 151 1.3E-31 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_15340 ba2bfd638731b813bb8fa902c8bc6559 164 Gene3D G3DSA:3.40.630.30 4 161 4.0E-38 T 14-10-2018 LH59_09760 4ad4e04c78ed4c4cc9f6f725acaa30e0 287 Pfam PF01418 Helix-turn-helix domain, rpiR family 2 74 6.1E-7 T 14-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 LH59_09760 4ad4e04c78ed4c4cc9f6f725acaa30e0 287 Gene3D G3DSA:3.40.50.10490 96 281 1.9E-31 T 14-10-2018 LH59_09760 4ad4e04c78ed4c4cc9f6f725acaa30e0 287 Gene3D G3DSA:1.10.10.10 1 76 6.9E-11 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_09760 4ad4e04c78ed4c4cc9f6f725acaa30e0 287 SUPERFAMILY SSF53697 101 262 1.62E-19 T 14-10-2018 LH59_09760 4ad4e04c78ed4c4cc9f6f725acaa30e0 287 SUPERFAMILY SSF46689 2 76 4.48E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_09760 4ad4e04c78ed4c4cc9f6f725acaa30e0 287 Pfam PF01380 SIS domain 129 256 1.1E-16 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 LH59_14285 a6df7730d2632512fb299f424600800d 414 Pfam PF00155 Aminotransferase class I and II 39 398 1.7E-66 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LH59_14285 a6df7730d2632512fb299f424600800d 414 SUPERFAMILY SSF53383 10 403 1.22E-101 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_14285 a6df7730d2632512fb299f424600800d 414 Gene3D G3DSA:3.40.640.10 69 291 2.6E-120 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_14285 a6df7730d2632512fb299f424600800d 414 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 241 254 - T 14-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 LH59_14285 a6df7730d2632512fb299f424600800d 414 Gene3D G3DSA:3.90.1150.10 30 397 2.6E-120 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_07580 0b60921d8361ca3b42a0b903f5513ee2 219 SMART SM00862 145 216 6.4E-22 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_07580 0b60921d8361ca3b42a0b903f5513ee2 219 Pfam PF00072 Response regulator receiver domain 3 112 2.9E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_07580 0b60921d8361ca3b42a0b903f5513ee2 219 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 215 5.6E-20 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_07580 0b60921d8361ca3b42a0b903f5513ee2 219 SUPERFAMILY SSF52172 1 177 4.84E-38 T 14-10-2018 IPR011006 CheY-like superfamily LH59_07580 0b60921d8361ca3b42a0b903f5513ee2 219 Gene3D G3DSA:1.10.10.10 122 218 9.5E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_07580 0b60921d8361ca3b42a0b903f5513ee2 219 Gene3D G3DSA:3.40.50.2300 1 121 2.3E-41 T 14-10-2018 LH59_07580 0b60921d8361ca3b42a0b903f5513ee2 219 SMART SM00448 1 112 5.2E-36 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_24550 12d074471c49a522f035cc9f9cd94bdc 313 Gene3D G3DSA:3.30.70.890 161 286 7.1E-22 T 14-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily LH59_24550 12d074471c49a522f035cc9f9cd94bdc 313 Pfam PF00288 GHMP kinases N terminal domain 87 143 1.1E-10 T 14-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 LH59_24550 12d074471c49a522f035cc9f9cd94bdc 313 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 4 280 32.54 T 14-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 LH59_24550 12d074471c49a522f035cc9f9cd94bdc 313 SUPERFAMILY SSF55060 159 276 9.59E-25 T 14-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily LH59_24550 12d074471c49a522f035cc9f9cd94bdc 313 SUPERFAMILY SSF54211 6 156 4.1E-46 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold LH59_24550 12d074471c49a522f035cc9f9cd94bdc 313 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 5 261 6.6E-69 T 14-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 LH59_24550 12d074471c49a522f035cc9f9cd94bdc 313 Gene3D G3DSA:3.30.230.10 1 158 1.2E-55 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup LH59_24550 12d074471c49a522f035cc9f9cd94bdc 313 PIRSF PIRSF010376 2 289 1.0E-86 T 14-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 LH59_04790 4a1f72de0db87e9475da6b4d516429f9 214 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 13 206 1.9E-49 T 14-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 LH59_04790 4a1f72de0db87e9475da6b4d516429f9 214 Gene3D G3DSA:3.20.20.70 6 214 4.4E-61 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_04790 4a1f72de0db87e9475da6b4d516429f9 214 Pfam PF01081 KDPG and KHG aldolase 13 201 3.9E-39 T 14-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 LH59_04790 4a1f72de0db87e9475da6b4d516429f9 214 SUPERFAMILY SSF51569 10 208 2.01E-53 T 14-10-2018 LH59_18220 20f39d8504de165fe4c57cfcf1e9215c 111 Gene3D G3DSA:3.10.20.30 1 94 3.4E-23 T 14-10-2018 IPR012675 Beta-grasp domain superfamily LH59_18220 20f39d8504de165fe4c57cfcf1e9215c 111 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 9 81 8.8E-14 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 LH59_18220 20f39d8504de165fe4c57cfcf1e9215c 111 SUPERFAMILY SSF54292 3 91 5.9E-26 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 LH59_12455 e1425db9015841e39945c992d5dc1c51 327 SUPERFAMILY SSF53850 21 321 2.08E-60 T 14-10-2018 LH59_12455 e1425db9015841e39945c992d5dc1c51 327 PIRSF PIRSF002825 8 324 3.4E-75 T 14-10-2018 IPR026045 Ferric binding protein LH59_12455 e1425db9015841e39945c992d5dc1c51 327 Gene3D G3DSA:3.40.190.10 28 292 1.8E-72 T 14-10-2018 LH59_12455 e1425db9015841e39945c992d5dc1c51 327 Pfam PF13343 Bacterial extracellular solute-binding protein 84 280 2.7E-31 T 14-10-2018 LH59_12455 e1425db9015841e39945c992d5dc1c51 327 Gene3D G3DSA:3.40.190.10 125 303 1.8E-72 T 14-10-2018 LH59_13675 40824390ea3cc2ffc773aaaa18e32010 366 SUPERFAMILY SSF51182 6 349 1.56E-53 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_13675 40824390ea3cc2ffc773aaaa18e32010 366 Gene3D G3DSA:2.60.120.10 200 353 4.6E-35 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_13675 40824390ea3cc2ffc773aaaa18e32010 366 Gene3D G3DSA:2.60.120.10 17 198 1.7E-19 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_13675 40824390ea3cc2ffc773aaaa18e32010 366 Pfam PF02311 AraC-like ligand binding domain 256 322 4.1E-7 T 14-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 LH59_03580 2c20505fc653825f46fe2abe5f85f9d2 273 PIRSF PIRSF005457 11 272 9.0E-96 T 14-10-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 LH59_03580 2c20505fc653825f46fe2abe5f85f9d2 273 Hamap MF_01374 Hydroxyacylglutathione hydrolase [gloB]. 15 272 42.71 T 14-10-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 LH59_03580 2c20505fc653825f46fe2abe5f85f9d2 273 TIGRFAM TIGR03413 GSH_gloB: hydroxyacylglutathione hydrolase 18 272 6.0E-99 T 14-10-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 LH59_03580 2c20505fc653825f46fe2abe5f85f9d2 273 SUPERFAMILY SSF56281 17 272 1.82E-68 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like LH59_03580 2c20505fc653825f46fe2abe5f85f9d2 273 Pfam PF16123 Hydroxyacylglutathione hydrolase C-terminus 185 272 3.2E-27 T 14-10-2018 IPR032282 Hydroxyacylglutathione hydrolase, C-terminal domain KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 LH59_03580 2c20505fc653825f46fe2abe5f85f9d2 273 Pfam PF00753 Metallo-beta-lactamase superfamily 27 184 2.2E-17 T 14-10-2018 IPR001279 Metallo-beta-lactamase LH59_03580 2c20505fc653825f46fe2abe5f85f9d2 273 Gene3D G3DSA:3.60.15.10 11 272 1.3E-83 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like LH59_03580 2c20505fc653825f46fe2abe5f85f9d2 273 SMART SM00849 25 184 8.0E-33 T 14-10-2018 IPR001279 Metallo-beta-lactamase LH59_03580 2c20505fc653825f46fe2abe5f85f9d2 273 ProSitePatterns PS00743 Beta-lactamases class B signature 1. 63 82 - T 14-10-2018 IPR001018 Beta-lactamase, class-B, conserved site GO:0008270|GO:0008800|GO:0017001 LH59_12645 9d332e4019834d87964bad450ef4cacd 201 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 2 175 1.1E-65 T 14-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 LH59_12645 9d332e4019834d87964bad450ef4cacd 201 Gene3D G3DSA:3.40.50.300 2 174 7.0E-62 T 14-10-2018 LH59_12645 9d332e4019834d87964bad450ef4cacd 201 Gene3D G3DSA:3.30.63.10 28 87 7.0E-62 T 14-10-2018 LH59_12645 9d332e4019834d87964bad450ef4cacd 201 ProSitePatterns PS00856 Guanylate kinase-like signature. 31 48 - T 14-10-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 LH59_12645 9d332e4019834d87964bad450ef4cacd 201 Pfam PF00625 Guanylate kinase 2 176 2.1E-42 T 14-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit LH59_12645 9d332e4019834d87964bad450ef4cacd 201 SMART SM00072 1 178 3.6E-54 T 14-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit LH59_12645 9d332e4019834d87964bad450ef4cacd 201 Hamap MF_00328 Guanylate kinase [gmk]. 1 178 33.601 T 14-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 LH59_12645 9d332e4019834d87964bad450ef4cacd 201 SUPERFAMILY SSF52540 2 180 2.01E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_04105 3b79beb10d2f073b0f631642121ba1cd 329 SUPERFAMILY SSF53850 118 291 3.65E-9 T 14-10-2018 LH59_04105 3b79beb10d2f073b0f631642121ba1cd 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 324 2.5E-76 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_04105 3b79beb10d2f073b0f631642121ba1cd 329 Gene3D G3DSA:3.40.190.10 129 253 1.0E-102 T 14-10-2018 LH59_04105 3b79beb10d2f073b0f631642121ba1cd 329 Gene3D G3DSA:3.40.190.150 32 318 1.0E-102 T 14-10-2018 LH59_04105 3b79beb10d2f073b0f631642121ba1cd 329 PIRSF PIRSF017082 1 327 5.1E-75 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_11595 24e59cff8c533c45411ff1167a70aa1d 138 SUPERFAMILY SSF51182 7 129 8.7E-29 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_11595 24e59cff8c533c45411ff1167a70aa1d 138 Gene3D G3DSA:2.60.120.10 11 128 2.3E-23 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_11595 24e59cff8c533c45411ff1167a70aa1d 138 Pfam PF07883 Cupin domain 49 116 3.4E-18 T 14-10-2018 IPR013096 Cupin 2, conserved barrel LH59_00155 7d43fc8b608e90074898b0e41da07fff 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 16 27 1.1E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_00155 7d43fc8b608e90074898b0e41da07fff 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 48 1.1E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_00155 7d43fc8b608e90074898b0e41da07fff 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 27 37 1.1E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_00155 7d43fc8b608e90074898b0e41da07fff 293 Gene3D G3DSA:1.10.10.10 1 81 2.0E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_00155 7d43fc8b608e90074898b0e41da07fff 293 Gene3D G3DSA:3.40.190.10 83 286 2.8E-60 T 14-10-2018 LH59_00155 7d43fc8b608e90074898b0e41da07fff 293 SUPERFAMILY SSF53850 83 290 1.36E-40 T 14-10-2018 LH59_00155 7d43fc8b608e90074898b0e41da07fff 293 SUPERFAMILY SSF46785 1 78 1.03E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_00155 7d43fc8b608e90074898b0e41da07fff 293 Gene3D G3DSA:3.40.190.10 164 263 2.8E-60 T 14-10-2018 LH59_00155 7d43fc8b608e90074898b0e41da07fff 293 Pfam PF03466 LysR substrate binding domain 88 290 7.0E-23 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_00155 7d43fc8b608e90074898b0e41da07fff 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 1 59 1.5E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_27395 d2319ff9e3faf716158ca2cec8f260ef 638 Gene3D G3DSA:3.40.50.300 7 238 3.2E-68 T 14-10-2018 LH59_27395 d2319ff9e3faf716158ca2cec8f260ef 638 Gene3D G3DSA:3.40.50.300 437 633 5.9E-75 T 14-10-2018 LH59_27395 d2319ff9e3faf716158ca2cec8f260ef 638 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 27 431 1.4E-189 T 14-10-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 LH59_27395 d2319ff9e3faf716158ca2cec8f260ef 638 Pfam PF00009 Elongation factor Tu GTP binding domain 26 212 7.9E-41 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_27395 d2319ff9e3faf716158ca2cec8f260ef 638 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 448 619 3.9E-75 T 14-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 LH59_27395 d2319ff9e3faf716158ca2cec8f260ef 638 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 82 97 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site LH59_27395 d2319ff9e3faf716158ca2cec8f260ef 638 Gene3D G3DSA:2.40.30.10 239 326 1.1E-21 T 14-10-2018 LH59_27395 d2319ff9e3faf716158ca2cec8f260ef 638 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 459 632 37.363 T 14-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 LH59_27395 d2319ff9e3faf716158ca2cec8f260ef 638 SUPERFAMILY SSF52540 21 234 4.73E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_27395 d2319ff9e3faf716158ca2cec8f260ef 638 PRINTS PR00315 GTP-binding elongation factor signature 28 41 2.4E-13 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_27395 d2319ff9e3faf716158ca2cec8f260ef 638 PRINTS PR00315 GTP-binding elongation factor signature 125 136 2.4E-13 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_27395 d2319ff9e3faf716158ca2cec8f260ef 638 PRINTS PR00315 GTP-binding elongation factor signature 89 97 2.4E-13 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_27395 d2319ff9e3faf716158ca2cec8f260ef 638 PRINTS PR00315 GTP-binding elongation factor signature 162 171 2.4E-13 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_27395 d2319ff9e3faf716158ca2cec8f260ef 638 PRINTS PR00315 GTP-binding elongation factor signature 109 119 2.4E-13 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_27395 d2319ff9e3faf716158ca2cec8f260ef 638 Hamap MF_00062 Sulfate adenylyltransferase subunit 1 [cysN]. 18 460 49.372 T 14-10-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 LH59_27395 d2319ff9e3faf716158ca2cec8f260ef 638 Pfam PF01583 Adenylylsulphate kinase 460 612 1.1E-69 T 14-10-2018 LH59_27395 d2319ff9e3faf716158ca2cec8f260ef 638 SUPERFAMILY SSF50447 241 327 2.5E-20 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily LH59_27395 d2319ff9e3faf716158ca2cec8f260ef 638 SUPERFAMILY SSF50465 329 432 2.78E-32 T 14-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal LH59_27395 d2319ff9e3faf716158ca2cec8f260ef 638 Gene3D G3DSA:2.40.30.10 329 432 1.7E-34 T 14-10-2018 LH59_27395 d2319ff9e3faf716158ca2cec8f260ef 638 SUPERFAMILY SSF52540 455 629 2.76E-34 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_05180 117f3ba28ce36534e6f152b5a9968d7a 346 PIRSF PIRSF000164 16 346 6.6E-96 T 14-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 LH59_05180 117f3ba28ce36534e6f152b5a9968d7a 346 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 85 104 - T 14-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 LH59_05180 117f3ba28ce36534e6f152b5a9968d7a 346 Pfam PF01180 Dihydroorotate dehydrogenase 53 340 4.3E-87 T 14-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 LH59_05180 117f3ba28ce36534e6f152b5a9968d7a 346 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 300 320 - T 14-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 LH59_05180 117f3ba28ce36534e6f152b5a9968d7a 346 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 8 345 1.0E-123 T 14-10-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 LH59_05180 117f3ba28ce36534e6f152b5a9968d7a 346 SUPERFAMILY SSF51395 8 343 5.33E-102 T 14-10-2018 LH59_05180 117f3ba28ce36534e6f152b5a9968d7a 346 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 7 344 48.899 T 14-10-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 LH59_05180 117f3ba28ce36534e6f152b5a9968d7a 346 Gene3D G3DSA:3.20.20.70 7 343 1.5E-129 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_14245 2d998cf2c935deaf72ccec1282f1978d 735 SUPERFAMILY SSF52821 459 554 1.83E-16 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily LH59_14245 2d998cf2c935deaf72ccec1282f1978d 735 Gene3D G3DSA:2.60.120.10 61 200 6.2E-19 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_14245 2d998cf2c935deaf72ccec1282f1978d 735 Gene3D G3DSA:3.40.250.10 329 435 9.4E-20 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily LH59_14245 2d998cf2c935deaf72ccec1282f1978d 735 SUPERFAMILY SSF51182 21 204 3.12E-29 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_14245 2d998cf2c935deaf72ccec1282f1978d 735 SUPERFAMILY SSF52821 578 684 2.1E-18 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily LH59_14245 2d998cf2c935deaf72ccec1282f1978d 735 Pfam PF00581 Rhodanese-like domain 214 303 3.1E-7 T 14-10-2018 IPR001763 Rhodanese-like domain LH59_14245 2d998cf2c935deaf72ccec1282f1978d 735 Pfam PF00581 Rhodanese-like domain 486 554 1.9E-4 T 14-10-2018 IPR001763 Rhodanese-like domain LH59_14245 2d998cf2c935deaf72ccec1282f1978d 735 Pfam PF00581 Rhodanese-like domain 585 671 2.5E-5 T 14-10-2018 IPR001763 Rhodanese-like domain LH59_14245 2d998cf2c935deaf72ccec1282f1978d 735 Pfam PF00581 Rhodanese-like domain 334 426 8.1E-6 T 14-10-2018 IPR001763 Rhodanese-like domain LH59_14245 2d998cf2c935deaf72ccec1282f1978d 735 Gene3D G3DSA:3.40.250.10 207 314 4.0E-17 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily LH59_14245 2d998cf2c935deaf72ccec1282f1978d 735 Gene3D G3DSA:3.40.250.10 580 682 1.9E-14 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily LH59_14245 2d998cf2c935deaf72ccec1282f1978d 735 SUPERFAMILY SSF52821 208 323 2.62E-23 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily LH59_14245 2d998cf2c935deaf72ccec1282f1978d 735 SMART SM00450 210 307 1.5E-8 T 14-10-2018 IPR001763 Rhodanese-like domain LH59_14245 2d998cf2c935deaf72ccec1282f1978d 735 SMART SM00450 470 567 2.7 T 14-10-2018 IPR001763 Rhodanese-like domain LH59_14245 2d998cf2c935deaf72ccec1282f1978d 735 SMART SM00450 581 675 0.0018 T 14-10-2018 IPR001763 Rhodanese-like domain LH59_14245 2d998cf2c935deaf72ccec1282f1978d 735 SMART SM00450 332 431 0.028 T 14-10-2018 IPR001763 Rhodanese-like domain LH59_14245 2d998cf2c935deaf72ccec1282f1978d 735 SUPERFAMILY SSF52821 308 434 6.16E-28 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily LH59_14245 2d998cf2c935deaf72ccec1282f1978d 735 Gene3D G3DSA:3.40.250.10 465 555 3.7E-16 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily LH59_14955 017b5fc878e6a10bc0efb80b9c0adff4 577 Gene3D G3DSA:3.40.50.970 2 185 5.6E-51 T 14-10-2018 LH59_14955 017b5fc878e6a10bc0efb80b9c0adff4 577 SUPERFAMILY SSF52518 377 558 3.04E-49 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold LH59_14955 017b5fc878e6a10bc0efb80b9c0adff4 577 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 8 170 1.9E-44 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 LH59_14955 017b5fc878e6a10bc0efb80b9c0adff4 577 SUPERFAMILY SSF52518 4 181 5.05E-46 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold LH59_14955 017b5fc878e6a10bc0efb80b9c0adff4 577 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 402 550 3.4E-34 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 LH59_14955 017b5fc878e6a10bc0efb80b9c0adff4 577 Gene3D G3DSA:3.40.50.1220 191 369 8.7E-43 T 14-10-2018 LH59_14955 017b5fc878e6a10bc0efb80b9c0adff4 577 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 438 457 - T 14-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 LH59_14955 017b5fc878e6a10bc0efb80b9c0adff4 577 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 201 334 1.2E-30 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 LH59_14955 017b5fc878e6a10bc0efb80b9c0adff4 577 Gene3D G3DSA:3.40.50.970 370 569 7.0E-52 T 14-10-2018 LH59_14955 017b5fc878e6a10bc0efb80b9c0adff4 577 SUPERFAMILY SSF52467 158 365 1.81E-40 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily LH59_11380 9c60f3bf1c8cd3d7d607791860677b1c 158 Pfam PF05130 FlgN protein 4 144 5.5E-25 T 14-10-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 LH59_11380 9c60f3bf1c8cd3d7d607791860677b1c 158 SUPERFAMILY SSF140566 4 128 1.23E-21 T 14-10-2018 IPR036679 FlgN-like superfamily GO:0005515|GO:0044780 LH59_11380 9c60f3bf1c8cd3d7d607791860677b1c 158 Gene3D G3DSA:1.20.58.300 5 128 3.4E-37 T 14-10-2018 LH59_24670 d0eb7f4cac977f0dc6014ceb955df86a 463 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 158 255 1.9E-26 T 14-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LH59_24670 d0eb7f4cac977f0dc6014ceb955df86a 463 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 374 451 9.8E-10 T 14-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LH59_24670 d0eb7f4cac977f0dc6014ceb955df86a 463 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 99 113 1.7E-23 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LH59_24670 d0eb7f4cac977f0dc6014ceb955df86a 463 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 206 219 1.7E-23 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LH59_24670 d0eb7f4cac977f0dc6014ceb955df86a 463 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 235 250 1.7E-23 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LH59_24670 d0eb7f4cac977f0dc6014ceb955df86a 463 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 172 191 1.7E-23 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LH59_24670 d0eb7f4cac977f0dc6014ceb955df86a 463 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 100 109 - T 14-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LH59_24670 d0eb7f4cac977f0dc6014ceb955df86a 463 SUPERFAMILY SSF53738 8 179 9.03E-37 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LH59_24670 d0eb7f4cac977f0dc6014ceb955df86a 463 SUPERFAMILY SSF53738 156 257 1.26E-31 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LH59_24670 d0eb7f4cac977f0dc6014ceb955df86a 463 Gene3D G3DSA:3.40.120.10 252 369 6.1E-39 T 14-10-2018 LH59_24670 d0eb7f4cac977f0dc6014ceb955df86a 463 Gene3D G3DSA:3.40.120.10 1 143 2.6E-46 T 14-10-2018 LH59_24670 d0eb7f4cac977f0dc6014ceb955df86a 463 SUPERFAMILY SSF53738 259 355 1.29E-31 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LH59_24670 d0eb7f4cac977f0dc6014ceb955df86a 463 Gene3D G3DSA:3.40.120.10 174 251 2.7E-33 T 14-10-2018 LH59_24670 d0eb7f4cac977f0dc6014ceb955df86a 463 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 260 355 2.3E-20 T 14-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LH59_24670 d0eb7f4cac977f0dc6014ceb955df86a 463 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 11 137 4.2E-33 T 14-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LH59_24670 d0eb7f4cac977f0dc6014ceb955df86a 463 Gene3D G3DSA:3.30.310.50 370 463 2.0E-25 T 14-10-2018 LH59_24670 d0eb7f4cac977f0dc6014ceb955df86a 463 SUPERFAMILY SSF55957 368 462 3.66E-19 T 14-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 LH59_19670 b87b32584f624388a36385094972a00c 318 PIRSF PIRSF006232 2 315 7.5E-49 T 14-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 LH59_19670 b87b32584f624388a36385094972a00c 318 Gene3D G3DSA:2.60.120.10 25 303 1.1E-52 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_19670 b87b32584f624388a36385094972a00c 318 Pfam PF05726 Pirin C-terminal cupin domain 165 308 5.7E-13 T 14-10-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 LH59_19670 b87b32584f624388a36385094972a00c 318 Pfam PF02678 Pirin 38 105 1.4E-11 T 14-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 LH59_19670 b87b32584f624388a36385094972a00c 318 Gene3D G3DSA:2.60.120.10 133 277 1.1E-52 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_19670 b87b32584f624388a36385094972a00c 318 SUPERFAMILY SSF51182 16 312 4.9E-45 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_27695 8128fd0e0d64cd29d40e832d0a39fdf1 338 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 253 265 - T 14-10-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 LH59_27695 8128fd0e0d64cd29d40e832d0a39fdf1 338 PIRSF PIRSF001415 4 337 1.8E-145 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 LH59_27695 8128fd0e0d64cd29d40e832d0a39fdf1 338 Gene3D G3DSA:3.20.20.70 3 338 1.2E-143 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_27695 8128fd0e0d64cd29d40e832d0a39fdf1 338 Pfam PF00490 Delta-aminolevulinic acid dehydratase 13 332 3.8E-137 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 LH59_27695 8128fd0e0d64cd29d40e832d0a39fdf1 338 SMART SM01004 10 334 3.9E-238 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 LH59_27695 8128fd0e0d64cd29d40e832d0a39fdf1 338 SUPERFAMILY SSF51569 7 336 2.78E-143 T 14-10-2018 LH59_27695 8128fd0e0d64cd29d40e832d0a39fdf1 338 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 308 327 2.8E-57 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 LH59_27695 8128fd0e0d64cd29d40e832d0a39fdf1 338 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 161 180 2.8E-57 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 LH59_27695 8128fd0e0d64cd29d40e832d0a39fdf1 338 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 278 293 2.8E-57 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 LH59_27695 8128fd0e0d64cd29d40e832d0a39fdf1 338 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 253 269 2.8E-57 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 LH59_27695 8128fd0e0d64cd29d40e832d0a39fdf1 338 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 199 218 2.8E-57 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 LH59_27695 8128fd0e0d64cd29d40e832d0a39fdf1 338 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 130 144 2.8E-57 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 LH59_03825 5b6f97019eef9193f664ba2c5aaf5a36 576 SUPERFAMILY SSF52954 467 574 1.54E-29 T 14-10-2018 LH59_03825 5b6f97019eef9193f664ba2c5aaf5a36 576 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 462 2.6E-46 T 14-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 LH59_03825 5b6f97019eef9193f664ba2c5aaf5a36 576 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 1.4E-17 T 14-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 LH59_03825 5b6f97019eef9193f664ba2c5aaf5a36 576 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 1.4E-17 T 14-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 LH59_03825 5b6f97019eef9193f664ba2c5aaf5a36 576 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 1.4E-17 T 14-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 LH59_03825 5b6f97019eef9193f664ba2c5aaf5a36 576 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 1.4E-17 T 14-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 LH59_03825 5b6f97019eef9193f664ba2c5aaf5a36 576 PIRSF PIRSF001535 1 576 3.5E-265 T 14-10-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 LH59_03825 5b6f97019eef9193f664ba2c5aaf5a36 576 Gene3D G3DSA:3.90.960.10 240 392 2.0E-232 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 LH59_03825 5b6f97019eef9193f664ba2c5aaf5a36 576 Pfam PF03129 Anticodon binding domain 478 570 5.0E-16 T 14-10-2018 IPR004154 Anticodon-binding LH59_03825 5b6f97019eef9193f664ba2c5aaf5a36 576 Gene3D G3DSA:3.40.50.800 4 557 2.0E-232 T 14-10-2018 IPR036621 Anticodon-binding domain superfamily LH59_03825 5b6f97019eef9193f664ba2c5aaf5a36 576 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 574 40.735 T 14-10-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 LH59_03825 5b6f97019eef9193f664ba2c5aaf5a36 576 SUPERFAMILY SSF55826 218 392 1.44E-33 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 LH59_03825 5b6f97019eef9193f664ba2c5aaf5a36 576 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 568 9.8E-224 T 14-10-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 LH59_03825 5b6f97019eef9193f664ba2c5aaf5a36 576 SUPERFAMILY SSF55681 10 481 4.98E-101 T 14-10-2018 LH59_03825 5b6f97019eef9193f664ba2c5aaf5a36 576 Gene3D G3DSA:3.30.930.10 11 468 2.0E-232 T 14-10-2018 LH59_03825 5b6f97019eef9193f664ba2c5aaf5a36 576 Pfam PF04073 Aminoacyl-tRNA editing domain 257 381 6.1E-29 T 14-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 LH59_09830 5c5d9bc81c05df7c45cd01f314468267 343 SMART SM00062 49 268 0.0011 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_09830 5c5d9bc81c05df7c45cd01f314468267 343 Gene3D G3DSA:3.40.190.10 56 327 1.8E-31 T 14-10-2018 LH59_09830 5c5d9bc81c05df7c45cd01f314468267 343 SUPERFAMILY SSF53850 47 278 5.44E-37 T 14-10-2018 LH59_09830 5c5d9bc81c05df7c45cd01f314468267 343 Gene3D G3DSA:3.40.190.10 131 232 1.8E-31 T 14-10-2018 LH59_09830 5c5d9bc81c05df7c45cd01f314468267 343 Pfam PF09084 NMT1/THI5 like 63 271 5.6E-18 T 14-10-2018 IPR015168 SsuA/THI5-like LH59_11075 63bcc736fe59f17d6abae540bee39511 314 PIRSF PIRSF002786 3 313 1.1E-66 T 14-10-2018 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 LH59_11075 63bcc736fe59f17d6abae540bee39511 314 Gene3D G3DSA:1.10.40.60 213 274 1.6E-22 T 14-10-2018 IPR038072 GspK, central domain superfamily LH59_11075 63bcc736fe59f17d6abae540bee39511 314 Gene3D G3DSA:3.30.1300.30 48 298 1.6E-22 T 14-10-2018 LH59_11075 63bcc736fe59f17d6abae540bee39511 314 Gene3D G3DSA:1.10.40.60 108 212 1.6E-22 T 14-10-2018 IPR038072 GspK, central domain superfamily LH59_11075 63bcc736fe59f17d6abae540bee39511 314 Pfam PF03934 Type II secretion system (T2SS), protein K 33 301 5.0E-60 T 14-10-2018 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 LH59_11075 63bcc736fe59f17d6abae540bee39511 314 SUPERFAMILY SSF54523 39 303 2.83E-5 T 14-10-2018 LH59_11075 63bcc736fe59f17d6abae540bee39511 314 SUPERFAMILY SSF158544 110 210 9.94E-6 T 14-10-2018 IPR038072 GspK, central domain superfamily LH59_19085 df48597d398ef6402cea8495aef16e55 129 SUPERFAMILY SSF46785 10 126 1.67E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_19085 df48597d398ef6402cea8495aef16e55 129 Pfam PF03965 Penicillinase repressor 12 125 1.4E-22 T 14-10-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 LH59_19085 df48597d398ef6402cea8495aef16e55 129 Gene3D G3DSA:1.10.10.10 9 75 3.4E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_13840 7d7d9a914a4d35d5771f395fd4fc7ad3 167 SUPERFAMILY SSF88946 11 71 5.1E-9 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 LH59_13840 7d7d9a914a4d35d5771f395fd4fc7ad3 167 Gene3D G3DSA:1.10.10.10 83 163 1.8E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_13840 7d7d9a914a4d35d5771f395fd4fc7ad3 167 Pfam PF04542 Sigma-70 region 2 13 73 2.5E-7 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 LH59_13840 7d7d9a914a4d35d5771f395fd4fc7ad3 167 SUPERFAMILY SSF88659 75 163 2.99E-14 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like LH59_13840 7d7d9a914a4d35d5771f395fd4fc7ad3 167 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 13 161 1.9E-18 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 LH59_13840 7d7d9a914a4d35d5771f395fd4fc7ad3 167 Pfam PF08281 Sigma-70, region 4 105 152 5.2E-13 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LH59_26455 73296c6e1946b1bd51aec48604a5ffd4 438 SMART SM00729 137 362 3.6E-53 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 LH59_26455 73296c6e1946b1bd51aec48604a5ffd4 438 Gene3D G3DSA:2.40.50.140 377 438 9.4E-21 T 14-10-2018 LH59_26455 73296c6e1946b1bd51aec48604a5ffd4 438 SUPERFAMILY SSF102114 117 367 1.16E-53 T 14-10-2018 LH59_26455 73296c6e1946b1bd51aec48604a5ffd4 438 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 5 435 2.5E-104 T 14-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 LH59_26455 73296c6e1946b1bd51aec48604a5ffd4 438 Pfam PF00919 Uncharacterized protein family UPF0004 5 83 6.6E-21 T 14-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 LH59_26455 73296c6e1946b1bd51aec48604a5ffd4 438 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 141 161 - T 14-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 LH59_26455 73296c6e1946b1bd51aec48604a5ffd4 438 Pfam PF04055 Radical SAM superfamily 143 319 2.6E-28 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 LH59_26455 73296c6e1946b1bd51aec48604a5ffd4 438 Gene3D G3DSA:3.80.30.20 135 376 3.0E-73 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe LH59_26455 73296c6e1946b1bd51aec48604a5ffd4 438 Gene3D G3DSA:3.40.50.12160 5 125 3.6E-29 T 14-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily LH59_26455 73296c6e1946b1bd51aec48604a5ffd4 438 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 5 434 1.7E-182 T 14-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 LH59_26455 73296c6e1946b1bd51aec48604a5ffd4 438 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 4 437 62.41 T 14-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 LH59_04325 9b5de2e8158ea520a265aed50caa2539 227 TIGRFAM TIGR01493 HAD-SF-IA-v2: HAD hydrolase, family IA, variant 2 14 176 1.8E-11 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 LH59_04325 9b5de2e8158ea520a265aed50caa2539 227 Gene3D G3DSA:3.40.50.1000 14 189 1.2E-33 T 14-10-2018 IPR023214 HAD superfamily LH59_04325 9b5de2e8158ea520a265aed50caa2539 227 Pfam PF13419 Haloacid dehalogenase-like hydrolase 14 183 4.0E-11 T 14-10-2018 LH59_04325 9b5de2e8158ea520a265aed50caa2539 227 Gene3D G3DSA:1.10.150.240 25 85 1.2E-33 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 LH59_04325 9b5de2e8158ea520a265aed50caa2539 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 11 22 8.2E-8 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 LH59_04325 9b5de2e8158ea520a265aed50caa2539 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 146 166 8.2E-8 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 LH59_04325 9b5de2e8158ea520a265aed50caa2539 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 173 186 8.2E-8 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 LH59_04325 9b5de2e8158ea520a265aed50caa2539 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 128 144 8.2E-8 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 LH59_04325 9b5de2e8158ea520a265aed50caa2539 227 SUPERFAMILY SSF56784 11 207 4.57E-32 T 14-10-2018 IPR036412 HAD-like superfamily LH59_05415 1a6e4e78e52bb93459404fd45b0cbe06 928 Gene3D G3DSA:3.40.50.300 25 234 2.1E-95 T 14-10-2018 LH59_05415 1a6e4e78e52bb93459404fd45b0cbe06 928 SUPERFAMILY SSF52402 258 360 3.18E-6 T 14-10-2018 LH59_05415 1a6e4e78e52bb93459404fd45b0cbe06 928 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 27 235 1.0E-91 T 14-10-2018 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 LH59_05415 1a6e4e78e52bb93459404fd45b0cbe06 928 SUPERFAMILY SSF47384 691 763 2.55E-16 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 LH59_05415 1a6e4e78e52bb93459404fd45b0cbe06 928 Gene3D G3DSA:1.20.120.620 429 534 5.0E-33 T 14-10-2018 IPR038318 KdpD, transmembrane domain superfamily LH59_05415 1a6e4e78e52bb93459404fd45b0cbe06 928 Gene3D G3DSA:3.30.450.40 543 688 6.1E-36 T 14-10-2018 IPR029016 GAF-like domain superfamily LH59_05415 1a6e4e78e52bb93459404fd45b0cbe06 928 SUPERFAMILY SSF55874 753 920 1.83E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_05415 1a6e4e78e52bb93459404fd45b0cbe06 928 Pfam PF13492 GAF domain 577 677 1.7E-10 T 14-10-2018 IPR003018 GAF domain GO:0005515 LH59_05415 1a6e4e78e52bb93459404fd45b0cbe06 928 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 811 918 5.3E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_05415 1a6e4e78e52bb93459404fd45b0cbe06 928 SUPERFAMILY SSF55781 545 689 2.47E-6 T 14-10-2018 LH59_05415 1a6e4e78e52bb93459404fd45b0cbe06 928 Gene3D G3DSA:3.30.565.10 770 919 3.4E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_05415 1a6e4e78e52bb93459404fd45b0cbe06 928 PRINTS PR00344 Bacterial sensor protein C-terminal signature 844 858 2.5E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_05415 1a6e4e78e52bb93459404fd45b0cbe06 928 PRINTS PR00344 Bacterial sensor protein C-terminal signature 877 895 2.5E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_05415 1a6e4e78e52bb93459404fd45b0cbe06 928 PRINTS PR00344 Bacterial sensor protein C-terminal signature 862 872 2.5E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_05415 1a6e4e78e52bb93459404fd45b0cbe06 928 PRINTS PR00344 Bacterial sensor protein C-terminal signature 903 916 2.5E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_05415 1a6e4e78e52bb93459404fd45b0cbe06 928 SMART SM00387 807 919 1.2E-32 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_05415 1a6e4e78e52bb93459404fd45b0cbe06 928 Gene3D G3DSA:3.40.50.620 239 364 7.3E-7 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LH59_05415 1a6e4e78e52bb93459404fd45b0cbe06 928 SMART SM00388 696 763 3.5E-16 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_05415 1a6e4e78e52bb93459404fd45b0cbe06 928 Gene3D G3DSA:1.10.287.130 701 764 2.3E-16 T 14-10-2018 LH59_05415 1a6e4e78e52bb93459404fd45b0cbe06 928 Pfam PF00512 His Kinase A (phospho-acceptor) domain 697 762 3.4E-14 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_05415 1a6e4e78e52bb93459404fd45b0cbe06 928 Pfam PF13493 Domain of unknown function (DUF4118) 434 539 2.0E-28 T 14-10-2018 IPR025201 Sensor protein KdpD, transmembrane domain LH59_12420 e18a6fb86debccb18b57f5267ad65615 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 174 199 8.4E-42 T 14-10-2018 LH59_12420 e18a6fb86debccb18b57f5267ad65615 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 306 313 8.4E-42 T 14-10-2018 LH59_12420 e18a6fb86debccb18b57f5267ad65615 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 262 276 8.4E-42 T 14-10-2018 LH59_12420 e18a6fb86debccb18b57f5267ad65615 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 8.4E-42 T 14-10-2018 LH59_12420 e18a6fb86debccb18b57f5267ad65615 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 138 147 8.4E-42 T 14-10-2018 LH59_12420 e18a6fb86debccb18b57f5267ad65615 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 406 421 8.4E-42 T 14-10-2018 LH59_12420 e18a6fb86debccb18b57f5267ad65615 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 428 448 8.4E-42 T 14-10-2018 LH59_12420 e18a6fb86debccb18b57f5267ad65615 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 8.4E-42 T 14-10-2018 LH59_12420 e18a6fb86debccb18b57f5267ad65615 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 343 364 8.4E-42 T 14-10-2018 LH59_12420 e18a6fb86debccb18b57f5267ad65615 478 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 349 453 5.0E-14 T 14-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 LH59_12420 e18a6fb86debccb18b57f5267ad65615 478 PIRSF PIRSF000350 2 460 2.8E-59 T 14-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 LH59_12420 e18a6fb86debccb18b57f5267ad65615 478 Gene3D G3DSA:1.10.287.990 37 107 1.2E-95 T 14-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 LH59_12420 e18a6fb86debccb18b57f5267ad65615 478 SUPERFAMILY SSF51905 1 361 2.31E-39 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_12420 e18a6fb86debccb18b57f5267ad65615 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 135 153 6.9E-17 T 14-10-2018 LH59_12420 e18a6fb86debccb18b57f5267ad65615 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 277 6.9E-17 T 14-10-2018 LH59_12420 e18a6fb86debccb18b57f5267ad65615 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 174 192 6.9E-17 T 14-10-2018 LH59_12420 e18a6fb86debccb18b57f5267ad65615 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 6.9E-17 T 14-10-2018 LH59_12420 e18a6fb86debccb18b57f5267ad65615 478 SUPERFAMILY SSF55424 346 460 6.19E-22 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 LH59_12420 e18a6fb86debccb18b57f5267ad65615 478 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 326 2.3E-35 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LH59_12420 e18a6fb86debccb18b57f5267ad65615 478 Gene3D G3DSA:3.30.390.30 346 464 2.5E-39 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 LH59_12420 e18a6fb86debccb18b57f5267ad65615 478 Gene3D G3DSA:3.50.50.60 7 329 1.2E-95 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_12420 e18a6fb86debccb18b57f5267ad65615 478 Gene3D G3DSA:3.50.50.60 147 268 1.2E-95 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_02930 d0820d48ab073be0b4857b0d480f96ba 871 Pfam PF13185 GAF domain 291 434 8.0E-16 T 14-10-2018 IPR003018 GAF domain GO:0005515 LH59_02930 d0820d48ab073be0b4857b0d480f96ba 871 SUPERFAMILY SSF55785 46 144 6.11E-16 T 14-10-2018 IPR035965 PAS domain superfamily LH59_02930 d0820d48ab073be0b4857b0d480f96ba 871 Pfam PF00563 EAL domain 622 857 5.4E-70 T 14-10-2018 IPR001633 EAL domain LH59_02930 d0820d48ab073be0b4857b0d480f96ba 871 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 444 604 1.2E-44 T 14-10-2018 IPR000160 GGDEF domain LH59_02930 d0820d48ab073be0b4857b0d480f96ba 871 SMART SM00065 292 443 2.4E-5 T 14-10-2018 IPR003018 GAF domain GO:0005515 LH59_02930 d0820d48ab073be0b4857b0d480f96ba 871 PIRSF PIRSF005925 146 871 4.3E-271 T 14-10-2018 IPR012226 Diguanylate cyclase/phosphodiesterase LH59_02930 d0820d48ab073be0b4857b0d480f96ba 871 PIRSF PIRSF005925 37 146 11.0 T 14-10-2018 IPR012226 Diguanylate cyclase/phosphodiesterase LH59_02930 d0820d48ab073be0b4857b0d480f96ba 871 Gene3D G3DSA:3.30.450.20 30 161 4.8E-16 T 14-10-2018 LH59_02930 d0820d48ab073be0b4857b0d480f96ba 871 SUPERFAMILY SSF55785 167 271 1.26E-15 T 14-10-2018 IPR035965 PAS domain superfamily LH59_02930 d0820d48ab073be0b4857b0d480f96ba 871 Gene3D G3DSA:3.30.450.40 293 442 7.1E-24 T 14-10-2018 IPR029016 GAF-like domain superfamily LH59_02930 d0820d48ab073be0b4857b0d480f96ba 871 SMART SM00267 435 606 2.6E-71 T 14-10-2018 IPR000160 GGDEF domain LH59_02930 d0820d48ab073be0b4857b0d480f96ba 871 SMART SM00052 616 862 8.5E-106 T 14-10-2018 IPR001633 EAL domain LH59_02930 d0820d48ab073be0b4857b0d480f96ba 871 SMART SM00091 158 225 4.2E-5 T 14-10-2018 IPR000014 PAS domain LH59_02930 d0820d48ab073be0b4857b0d480f96ba 871 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 165 274 2.7E-10 T 14-10-2018 IPR000014 PAS domain LH59_02930 d0820d48ab073be0b4857b0d480f96ba 871 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 49 143 1.1E-5 T 14-10-2018 IPR000014 PAS domain LH59_02930 d0820d48ab073be0b4857b0d480f96ba 871 Gene3D G3DSA:3.30.450.20 163 292 3.6E-19 T 14-10-2018 LH59_02930 d0820d48ab073be0b4857b0d480f96ba 871 Pfam PF08447 PAS fold 57 142 6.5E-9 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 LH59_02930 d0820d48ab073be0b4857b0d480f96ba 871 SUPERFAMILY SSF55073 451 607 2.28E-51 T 14-10-2018 IPR029787 Nucleotide cyclase LH59_02930 d0820d48ab073be0b4857b0d480f96ba 871 SUPERFAMILY SSF141868 622 869 3.66E-82 T 14-10-2018 IPR035919 EAL domain superfamily LH59_02930 d0820d48ab073be0b4857b0d480f96ba 871 Pfam PF00990 Diguanylate cyclase, GGDEF domain 446 602 2.2E-49 T 14-10-2018 IPR000160 GGDEF domain LH59_02930 d0820d48ab073be0b4857b0d480f96ba 871 SMART SM00086 231 273 3.3 T 14-10-2018 IPR001610 PAC motif LH59_02930 d0820d48ab073be0b4857b0d480f96ba 871 SMART SM00086 108 146 0.069 T 14-10-2018 IPR001610 PAC motif LH59_02930 d0820d48ab073be0b4857b0d480f96ba 871 SUPERFAMILY SSF55781 295 446 4.17E-23 T 14-10-2018 LH59_02930 d0820d48ab073be0b4857b0d480f96ba 871 Gene3D G3DSA:3.20.20.450 619 870 7.3E-93 T 14-10-2018 IPR035919 EAL domain superfamily LH59_02930 d0820d48ab073be0b4857b0d480f96ba 871 Pfam PF13426 PAS domain 170 271 2.7E-13 T 14-10-2018 IPR000014 PAS domain LH59_02930 d0820d48ab073be0b4857b0d480f96ba 871 Gene3D G3DSA:3.30.70.270 443 618 2.5E-62 T 14-10-2018 LH59_26520 82c0695830c6c72b6ac5ef66c5968053 338 Gene3D G3DSA:3.40.190.10 23 253 6.3E-50 T 14-10-2018 LH59_26520 82c0695830c6c72b6ac5ef66c5968053 338 SUPERFAMILY SSF53850 24 255 9.49E-48 T 14-10-2018 LH59_26520 82c0695830c6c72b6ac5ef66c5968053 338 SMART SM00062 33 263 1.9E-47 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_26520 82c0695830c6c72b6ac5ef66c5968053 338 Gene3D G3DSA:3.40.190.10 125 221 6.3E-50 T 14-10-2018 LH59_26520 82c0695830c6c72b6ac5ef66c5968053 338 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 35 253 2.1E-31 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_26520 82c0695830c6c72b6ac5ef66c5968053 338 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 56 69 - T 14-10-2018 IPR018313 Solute-binding protein family 3, conserved site LH59_11700 3a2e05ea739947c68fde7aae5f221ac6 151 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 3 146 8.4E-59 T 14-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 LH59_11700 3a2e05ea739947c68fde7aae5f221ac6 151 Pfam PF07977 FabA-like domain 12 141 1.1E-41 T 14-10-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 LH59_11700 3a2e05ea739947c68fde7aae5f221ac6 151 SUPERFAMILY SSF54637 5 147 2.22E-49 T 14-10-2018 IPR029069 HotDog domain superfamily LH59_11700 3a2e05ea739947c68fde7aae5f221ac6 151 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 3 148 34.306 T 14-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 LH59_11700 3a2e05ea739947c68fde7aae5f221ac6 151 Gene3D G3DSA:3.10.129.10 1 149 2.8E-59 T 14-10-2018 LH59_09810 129cc6c9234e1e65d14cc7a72676c7b0 313 Gene3D G3DSA:3.40.190.10 164 267 5.3E-46 T 14-10-2018 LH59_09810 129cc6c9234e1e65d14cc7a72676c7b0 313 Gene3D G3DSA:1.10.10.10 6 90 5.6E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_09810 129cc6c9234e1e65d14cc7a72676c7b0 313 SUPERFAMILY SSF53850 86 300 1.09E-28 T 14-10-2018 LH59_09810 129cc6c9234e1e65d14cc7a72676c7b0 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 67 1.2E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_09810 129cc6c9234e1e65d14cc7a72676c7b0 313 SUPERFAMILY SSF46785 3 86 5.64E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_09810 129cc6c9234e1e65d14cc7a72676c7b0 313 Pfam PF03466 LysR substrate binding domain 92 298 7.9E-28 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_09810 129cc6c9234e1e65d14cc7a72676c7b0 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.2E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_09810 129cc6c9234e1e65d14cc7a72676c7b0 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.2E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_09810 129cc6c9234e1e65d14cc7a72676c7b0 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.2E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_09810 129cc6c9234e1e65d14cc7a72676c7b0 313 Gene3D G3DSA:3.40.190.10 103 294 5.3E-46 T 14-10-2018 LH59_18465 827f31d9fe5d8360b0e3a3c775785030 421 SUPERFAMILY SSF53474 5 409 5.31E-87 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_18465 827f31d9fe5d8360b0e3a3c775785030 421 Gene3D G3DSA:3.40.50.1820 4 317 4.4E-89 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_18465 827f31d9fe5d8360b0e3a3c775785030 421 Pfam PF00135 Carboxylesterase family 8 310 1.8E-70 T 14-10-2018 IPR002018 Carboxylesterase, type B LH59_18465 827f31d9fe5d8360b0e3a3c775785030 421 Gene3D G3DSA:3.40.50.1820 318 419 1.7E-11 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_23160 330218e5edb854799737f4b32d416f8f 482 Pfam PF02805 Metal binding domain of Ada 7 71 2.6E-28 T 14-10-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 LH59_23160 330218e5edb854799737f4b32d416f8f 482 Gene3D G3DSA:3.40.10.10 1 73 2.7E-29 T 14-10-2018 IPR035451 Ada-like domain superfamily LH59_23160 330218e5edb854799737f4b32d416f8f 482 SMART SM01009 199 315 1.0E-54 T 14-10-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal LH59_23160 330218e5edb854799737f4b32d416f8f 482 SMART SM00478 325 482 5.2E-16 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 LH59_23160 330218e5edb854799737f4b32d416f8f 482 Gene3D G3DSA:1.10.340.30 316 430 3.4E-24 T 14-10-2018 LH59_23160 330218e5edb854799737f4b32d416f8f 482 Pfam PF06029 AlkA N-terminal domain 200 315 9.6E-38 T 14-10-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal LH59_23160 330218e5edb854799737f4b32d416f8f 482 Gene3D G3DSA:1.10.1670.10 433 482 8.4E-13 T 14-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 LH59_23160 330218e5edb854799737f4b32d416f8f 482 SUPERFAMILY SSF57884 2 76 1.44E-30 T 14-10-2018 IPR035451 Ada-like domain superfamily LH59_23160 330218e5edb854799737f4b32d416f8f 482 Pfam PF12833 Helix-turn-helix domain 106 184 1.3E-21 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_23160 330218e5edb854799737f4b32d416f8f 482 SUPERFAMILY SSF46689 136 186 2.69E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_23160 330218e5edb854799737f4b32d416f8f 482 Gene3D G3DSA:3.30.310.20 199 315 5.2E-35 T 14-10-2018 IPR037046 DNA-3-methyladenine glycosylase AlkA, N-terminal domain superfamily LH59_23160 330218e5edb854799737f4b32d416f8f 482 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 322 471 2.0E-6 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 LH59_23160 330218e5edb854799737f4b32d416f8f 482 SUPERFAMILY SSF48150 305 480 7.15E-38 T 14-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 LH59_23160 330218e5edb854799737f4b32d416f8f 482 Gene3D G3DSA:1.10.10.60 82 188 1.4E-19 T 14-10-2018 LH59_23160 330218e5edb854799737f4b32d416f8f 482 SMART SM00342 100 183 1.7E-20 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_23160 330218e5edb854799737f4b32d416f8f 482 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 137 179 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 LH59_23160 330218e5edb854799737f4b32d416f8f 482 SUPERFAMILY SSF55945 200 296 5.81E-28 T 14-10-2018 LH59_23345 48041ef2afc07c8c190304d5cf1e5869 204 TIGRFAM TIGR02842 CyoC: cytochrome o ubiquinol oxidase, subunit III 25 204 9.6E-85 T 14-10-2018 IPR014206 Cytochrome o ubiquinol oxidase, subunit III GO:0005886|GO:0008827|GO:0019646 LH59_23345 48041ef2afc07c8c190304d5cf1e5869 204 Gene3D G3DSA:1.20.120.80 19 204 1.1E-57 T 14-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_23345 48041ef2afc07c8c190304d5cf1e5869 204 Pfam PF00510 Cytochrome c oxidase subunit III 26 202 6.6E-15 T 14-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_23345 48041ef2afc07c8c190304d5cf1e5869 204 SUPERFAMILY SSF81452 7 202 2.88E-57 T 14-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_17145 8a69d7ce4b6303e5d8c72f565a12c717 267 Pfam PF00378 Enoyl-CoA hydratase/isomerase 15 266 3.4E-49 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 LH59_17145 8a69d7ce4b6303e5d8c72f565a12c717 267 Gene3D G3DSA:3.90.226.10 2 208 6.3E-58 T 14-10-2018 LH59_17145 8a69d7ce4b6303e5d8c72f565a12c717 267 SUPERFAMILY SSF52096 8 267 4.35E-74 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily LH59_17145 8a69d7ce4b6303e5d8c72f565a12c717 267 Gene3D G3DSA:1.10.12.10 211 267 3.4E-16 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal LH59_17145 8a69d7ce4b6303e5d8c72f565a12c717 267 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 108 128 - T 14-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 LH59_25835 fc9037a12439655f2b7b87b8d0a59326 250 Pfam PF00005 ABC transporter 22 177 2.9E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_25835 fc9037a12439655f2b7b87b8d0a59326 250 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 224 246 2.1E-10 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal LH59_25835 fc9037a12439655f2b7b87b8d0a59326 250 Gene3D G3DSA:3.40.50.300 1 247 4.5E-55 T 14-10-2018 LH59_25835 fc9037a12439655f2b7b87b8d0a59326 250 SMART SM00382 30 224 6.0E-4 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_25835 fc9037a12439655f2b7b87b8d0a59326 250 SUPERFAMILY SSF52540 5 246 4.92E-55 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_09815 660fee8e37e7b20fa661683d1c20cd95 329 PIRSF PIRSF017082 1 329 2.9E-87 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_09815 660fee8e37e7b20fa661683d1c20cd95 329 SUPERFAMILY SSF53850 116 291 8.41E-13 T 14-10-2018 LH59_09815 660fee8e37e7b20fa661683d1c20cd95 329 Gene3D G3DSA:3.40.190.150 33 319 2.2E-113 T 14-10-2018 LH59_09815 660fee8e37e7b20fa661683d1c20cd95 329 Gene3D G3DSA:3.40.190.10 131 254 2.2E-113 T 14-10-2018 LH59_09815 660fee8e37e7b20fa661683d1c20cd95 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 325 3.6E-81 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_17070 b8709b656b100793f17a7135b53df017 436 Pfam PF07690 Major Facilitator Superfamily 34 395 5.3E-46 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_17070 b8709b656b100793f17a7135b53df017 436 SUPERFAMILY SSF103473 14 429 3.27E-87 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_17070 b8709b656b100793f17a7135b53df017 436 Gene3D G3DSA:1.20.1250.20 15 433 1.5E-82 T 14-10-2018 LH59_00675 49667cf9b7a4bd7d0c243895348800b7 265 Pfam PF00149 Calcineurin-like phosphoesterase 2 198 5.5E-17 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 LH59_00675 49667cf9b7a4bd7d0c243895348800b7 265 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 1 255 37.824 T 14-10-2018 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 LH59_00675 49667cf9b7a4bd7d0c243895348800b7 265 Gene3D G3DSA:3.60.21.40 1 241 4.7E-94 T 14-10-2018 LH59_00675 49667cf9b7a4bd7d0c243895348800b7 265 SUPERFAMILY SSF56300 1 255 1.98E-57 T 14-10-2018 LH59_00675 49667cf9b7a4bd7d0c243895348800b7 265 Gene3D G3DSA:3.30.750.180 105 232 4.7E-94 T 14-10-2018 LH59_09190 4769b5519020d0ba755d73fb8faef6f5 355 SUPERFAMILY SSF53383 5 354 8.74E-81 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_09190 4769b5519020d0ba755d73fb8faef6f5 355 Gene3D G3DSA:3.40.640.10 38 263 1.2E-106 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_09190 4769b5519020d0ba755d73fb8faef6f5 355 Pfam PF00155 Aminotransferase class I and II 25 351 4.7E-59 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LH59_09190 4769b5519020d0ba755d73fb8faef6f5 355 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 9 354 9.4E-93 T 14-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 LH59_09190 4769b5519020d0ba755d73fb8faef6f5 355 Gene3D G3DSA:3.90.1150.10 20 344 1.2E-106 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_09190 4769b5519020d0ba755d73fb8faef6f5 355 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 4 355 55.66 T 14-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 LH59_09190 4769b5519020d0ba755d73fb8faef6f5 355 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 211 220 - T 14-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 LH59_04765 764337b9461296df2a680e70cd9a7982 300 Gene3D G3DSA:1.10.10.10 1 88 6.8E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_04765 764337b9461296df2a680e70cd9a7982 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 1.7E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_04765 764337b9461296df2a680e70cd9a7982 300 Gene3D G3DSA:3.40.190.10 92 293 4.5E-73 T 14-10-2018 LH59_04765 764337b9461296df2a680e70cd9a7982 300 SUPERFAMILY SSF46785 2 85 2.72E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_04765 764337b9461296df2a680e70cd9a7982 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 2.6E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_04765 764337b9461296df2a680e70cd9a7982 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 2.6E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_04765 764337b9461296df2a680e70cd9a7982 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 2.6E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_04765 764337b9461296df2a680e70cd9a7982 300 Pfam PF03466 LysR substrate binding domain 98 298 6.7E-28 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_04765 764337b9461296df2a680e70cd9a7982 300 SUPERFAMILY SSF53850 90 296 1.93E-43 T 14-10-2018 LH59_04765 764337b9461296df2a680e70cd9a7982 300 Gene3D G3DSA:3.40.190.10 171 269 4.5E-73 T 14-10-2018 LH59_06645 901cd11b559abae01a20e1e70406c99a 109 Pfam PF10087 Uncharacterized protein conserved in bacteria (DUF2325) 6 97 9.6E-18 T 14-10-2018 IPR016772 Uncharacterised conserved protein UCP020408 LH59_06645 901cd11b559abae01a20e1e70406c99a 109 PIRSF PIRSF020408 5 108 4.7E-42 T 14-10-2018 IPR016772 Uncharacterised conserved protein UCP020408 LH59_02705 b3abc481184f3a5a4728aa733690f4c7 450 SUPERFAMILY SSF51905 4 421 6.49E-22 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_02705 b3abc481184f3a5a4728aa733690f4c7 450 Gene3D G3DSA:3.50.50.60 14 211 6.7E-18 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_02705 b3abc481184f3a5a4728aa733690f4c7 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 344 351 4.2E-7 T 14-10-2018 LH59_02705 b3abc481184f3a5a4728aa733690f4c7 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 17 39 4.2E-7 T 14-10-2018 LH59_02705 b3abc481184f3a5a4728aa733690f4c7 450 Pfam PF12831 FAD dependent oxidoreductase 17 439 3.9E-108 T 14-10-2018 IPR039649 Digeranylgeranylglycerophospholipid reductase, N-terminal LH59_20410 51df794398964eea57807ac3988de714 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 324 6.4E-102 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_20410 51df794398964eea57807ac3988de714 329 PIRSF PIRSF017082 4 328 3.7E-91 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_20410 51df794398964eea57807ac3988de714 329 SUPERFAMILY SSF53850 113 293 1.52E-16 T 14-10-2018 LH59_20410 51df794398964eea57807ac3988de714 329 Gene3D G3DSA:3.40.190.10 131 254 1.9E-122 T 14-10-2018 LH59_20410 51df794398964eea57807ac3988de714 329 Gene3D G3DSA:3.40.190.150 34 319 1.9E-122 T 14-10-2018 LH59_17980 e30e958175dd6ca4d17618197d29d68e 519 PIRSF PIRSF002869 1 518 2.4E-148 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ LH59_17980 e30e958175dd6ca4d17618197d29d68e 519 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 2 508 1.0E-139 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ LH59_17980 e30e958175dd6ca4d17618197d29d68e 519 PRINTS PR01806 Virulence factor MviN signature 415 432 7.0E-77 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ LH59_17980 e30e958175dd6ca4d17618197d29d68e 519 PRINTS PR01806 Virulence factor MviN signature 363 382 7.0E-77 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ LH59_17980 e30e958175dd6ca4d17618197d29d68e 519 PRINTS PR01806 Virulence factor MviN signature 33 52 7.0E-77 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ LH59_17980 e30e958175dd6ca4d17618197d29d68e 519 PRINTS PR01806 Virulence factor MviN signature 265 291 7.0E-77 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ LH59_17980 e30e958175dd6ca4d17618197d29d68e 519 PRINTS PR01806 Virulence factor MviN signature 135 159 7.0E-77 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ LH59_17980 e30e958175dd6ca4d17618197d29d68e 519 PRINTS PR01806 Virulence factor MviN signature 159 180 7.0E-77 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ LH59_17980 e30e958175dd6ca4d17618197d29d68e 519 PRINTS PR01806 Virulence factor MviN signature 52 68 7.0E-77 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ LH59_17980 e30e958175dd6ca4d17618197d29d68e 519 Hamap MF_02078 Probable lipid II flippase MurJ [murJ]. 3 473 19.522 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ LH59_17980 e30e958175dd6ca4d17618197d29d68e 519 Pfam PF03023 MviN-like protein 28 469 2.9E-131 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ LH59_00995 64225bf37d56ce032ac330051ccf8124 209 Gene3D G3DSA:3.10.450.50 43 179 3.2E-57 T 14-10-2018 LH59_00995 64225bf37d56ce032ac330051ccf8124 209 Pfam PF05494 MlaC protein 43 206 7.7E-56 T 14-10-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC LH59_00995 64225bf37d56ce032ac330051ccf8124 209 PIRSF PIRSF004649 7 209 3.5E-50 T 14-10-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC LH59_00995 64225bf37d56ce032ac330051ccf8124 209 Gene3D G3DSA:1.10.10.640 79 204 3.2E-57 T 14-10-2018 LH59_11205 e3359ee638b7781eae0ec8b0a72977c0 496 SUPERFAMILY SSF56954 2 475 7.06E-119 T 14-10-2018 LH59_11205 e3359ee638b7781eae0ec8b0a72977c0 496 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 13 472 3.0E-135 T 14-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 LH59_11205 e3359ee638b7781eae0ec8b0a72977c0 496 Pfam PF02321 Outer membrane efflux protein 67 257 4.6E-29 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 LH59_11205 e3359ee638b7781eae0ec8b0a72977c0 496 Pfam PF02321 Outer membrane efflux protein 288 470 1.3E-30 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 LH59_11205 e3359ee638b7781eae0ec8b0a72977c0 496 Gene3D G3DSA:2.20.200.10 104 361 1.9E-146 T 14-10-2018 LH59_11205 e3359ee638b7781eae0ec8b0a72977c0 496 Gene3D G3DSA:1.20.1600.10 58 472 1.9E-146 T 14-10-2018 LH59_23875 5f5a4803d1e1b6c9fb96351a2812561f 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 65 1.7E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_23875 5f5a4803d1e1b6c9fb96351a2812561f 296 Gene3D G3DSA:3.40.190.10 93 292 5.4E-68 T 14-10-2018 LH59_23875 5f5a4803d1e1b6c9fb96351a2812561f 296 SUPERFAMILY SSF46785 9 113 1.99E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_23875 5f5a4803d1e1b6c9fb96351a2812561f 296 Gene3D G3DSA:1.10.10.10 6 90 9.1E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_23875 5f5a4803d1e1b6c9fb96351a2812561f 296 Gene3D G3DSA:3.40.190.10 165 266 5.4E-68 T 14-10-2018 LH59_23875 5f5a4803d1e1b6c9fb96351a2812561f 296 Pfam PF03466 LysR substrate binding domain 92 295 4.2E-47 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_23875 5f5a4803d1e1b6c9fb96351a2812561f 296 SUPERFAMILY SSF53850 92 296 1.27E-49 T 14-10-2018 LH59_00130 e3cf5192d439ec4e7e8fd4b13d31d13b 459 Gene3D G3DSA:1.10.10.1100 360 430 5.4E-20 T 14-10-2018 LH59_00130 e3cf5192d439ec4e7e8fd4b13d31d13b 459 Gene3D G3DSA:3.50.50.60 118 256 2.4E-37 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_00130 e3cf5192d439ec4e7e8fd4b13d31d13b 459 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 290 308 1.8E-6 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 LH59_00130 e3cf5192d439ec4e7e8fd4b13d31d13b 459 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 107 115 1.8E-6 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 LH59_00130 e3cf5192d439ec4e7e8fd4b13d31d13b 459 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 1.8E-6 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 LH59_00130 e3cf5192d439ec4e7e8fd4b13d31d13b 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 3.1E-11 T 14-10-2018 LH59_00130 e3cf5192d439ec4e7e8fd4b13d31d13b 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 3.1E-11 T 14-10-2018 LH59_00130 e3cf5192d439ec4e7e8fd4b13d31d13b 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 280 302 3.1E-11 T 14-10-2018 LH59_00130 e3cf5192d439ec4e7e8fd4b13d31d13b 459 SUPERFAMILY SSF51905 5 323 1.38E-34 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_00130 e3cf5192d439ec4e7e8fd4b13d31d13b 459 Pfam PF04324 BFD-like [2Fe-2S] binding domain 370 422 1.2E-11 T 14-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain LH59_00130 e3cf5192d439ec4e7e8fd4b13d31d13b 459 PIRSF PIRSF037495 2 458 7.1E-142 T 14-10-2018 IPR017224 Opine oxidase, subunit A/hydrogen cyanide synthase, subunit B GO:0016491|GO:0055114 LH59_00130 e3cf5192d439ec4e7e8fd4b13d31d13b 459 Gene3D G3DSA:3.50.50.60 5 314 2.4E-37 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_00130 e3cf5192d439ec4e7e8fd4b13d31d13b 459 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 307 3.9E-22 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LH59_25395 4467b085028e755aa94c229764836090 319 PIRSF PIRSF017082 1 319 3.0E-101 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_25395 4467b085028e755aa94c229764836090 319 Gene3D G3DSA:3.40.190.10 124 245 3.2E-90 T 14-10-2018 LH59_25395 4467b085028e755aa94c229764836090 319 Gene3D G3DSA:3.40.190.150 28 310 3.2E-90 T 14-10-2018 LH59_25395 4467b085028e755aa94c229764836090 319 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 307 1.7E-53 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_05295 5bd28994065c9ae8a0e32db8cad59422 363 ProSitePatterns PS00534 Ferrochelatase signature. 223 242 - T 14-10-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 LH59_05295 5bd28994065c9ae8a0e32db8cad59422 363 SUPERFAMILY SSF53800 34 359 2.45E-105 T 14-10-2018 LH59_05295 5bd28994065c9ae8a0e32db8cad59422 363 Gene3D G3DSA:3.40.50.1400 37 354 7.3E-97 T 14-10-2018 LH59_05295 5bd28994065c9ae8a0e32db8cad59422 363 TIGRFAM TIGR00109 hemH: ferrochelatase 34 354 3.1E-91 T 14-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 LH59_05295 5bd28994065c9ae8a0e32db8cad59422 363 Gene3D G3DSA:3.40.50.1400 197 335 7.3E-97 T 14-10-2018 LH59_05295 5bd28994065c9ae8a0e32db8cad59422 363 Pfam PF00762 Ferrochelatase 35 354 2.9E-111 T 14-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 LH59_05295 5bd28994065c9ae8a0e32db8cad59422 363 Hamap MF_00323 Ferrochelatase [hemH]. 34 354 38.359 T 14-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 LH59_02150 91c8760c84395428efda9852bac056f7 289 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 23 277 1.6E-53 T 14-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 LH59_02150 91c8760c84395428efda9852bac056f7 289 Pfam PF01256 Carbohydrate kinase 36 263 2.5E-46 T 14-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 LH59_02150 91c8760c84395428efda9852bac056f7 289 SUPERFAMILY SSF53613 15 281 2.31E-62 T 14-10-2018 IPR029056 Ribokinase-like LH59_02150 91c8760c84395428efda9852bac056f7 289 Gene3D G3DSA:3.40.1190.20 9 283 2.1E-74 T 14-10-2018 IPR029056 Ribokinase-like LH59_02150 91c8760c84395428efda9852bac056f7 289 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 13 284 20.989 T 14-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 LH59_02150 91c8760c84395428efda9852bac056f7 289 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 222 232 - T 14-10-2018 IPR017953 Carbohydrate kinase, predicted, conserved site LH59_22685 26129b636a0646e67636e164707b9bf7 432 Gene3D G3DSA:3.40.190.10 64 416 4.9E-122 T 14-10-2018 LH59_22685 26129b636a0646e67636e164707b9bf7 432 Gene3D G3DSA:3.40.190.10 150 421 4.9E-122 T 14-10-2018 LH59_22685 26129b636a0646e67636e164707b9bf7 432 Pfam PF13379 NMT1-like family 57 307 2.4E-103 T 14-10-2018 LH59_22685 26129b636a0646e67636e164707b9bf7 432 SUPERFAMILY SSF53850 61 298 1.19E-28 T 14-10-2018 LH59_01635 f15524f32486a5db6839ac45439b4020 321 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 37 314 1.0E-72 T 14-10-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 LH59_01635 f15524f32486a5db6839ac45439b4020 321 SMART SM00062 36 267 1.4E-29 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_01635 f15524f32486a5db6839ac45439b4020 321 Pfam PF09084 NMT1/THI5 like 62 256 6.7E-17 T 14-10-2018 IPR015168 SsuA/THI5-like LH59_01635 f15524f32486a5db6839ac45439b4020 321 SUPERFAMILY SSF53850 35 273 7.81E-55 T 14-10-2018 LH59_01635 f15524f32486a5db6839ac45439b4020 321 Gene3D G3DSA:3.40.190.10 116 215 2.3E-109 T 14-10-2018 LH59_01635 f15524f32486a5db6839ac45439b4020 321 Gene3D G3DSA:1.10.8.450 247 279 2.3E-109 T 14-10-2018 LH59_01635 f15524f32486a5db6839ac45439b4020 321 Gene3D G3DSA:3.40.190.10 37 309 2.3E-109 T 14-10-2018 LH59_17440 8e522964a2ba9c436d66614aa7e5dfdb 257 SUPERFAMILY SSF102712 1 141 6.28E-21 T 14-10-2018 LH59_17440 8e522964a2ba9c436d66614aa7e5dfdb 257 Gene3D G3DSA:3.90.1720.10 117 256 8.6E-7 T 14-10-2018 LH59_17440 8e522964a2ba9c436d66614aa7e5dfdb 257 SUPERFAMILY SSF54001 114 255 7.06E-10 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily LH59_17440 8e522964a2ba9c436d66614aa7e5dfdb 257 Pfam PF00877 NlpC/P60 family 124 254 3.7E-14 T 14-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain LH59_17440 8e522964a2ba9c436d66614aa7e5dfdb 257 SMART SM00232 1 118 6.0E-6 T 14-10-2018 IPR000555 JAB1/MPN/MOV34 metalloenzyme domain GO:0005515 LH59_17440 8e522964a2ba9c436d66614aa7e5dfdb 257 Pfam PF14464 Prokaryotic homologs of the JAB domain 3 102 1.2E-20 T 14-10-2018 IPR028090 JAB domain, prokaryotic LH59_17440 8e522964a2ba9c436d66614aa7e5dfdb 257 Gene3D G3DSA:3.40.140.10 1 111 8.2E-23 T 14-10-2018 LH59_07740 f6e1896071d48781a2afb12e9b5b1e10 376 SMART SM00382 52 235 2.8E-19 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_07740 f6e1896071d48781a2afb12e9b5b1e10 376 SUPERFAMILY SSF52540 28 267 6.53E-85 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_07740 f6e1896071d48781a2afb12e9b5b1e10 376 Gene3D G3DSA:3.40.50.300 25 262 5.1E-78 T 14-10-2018 LH59_07740 f6e1896071d48781a2afb12e9b5b1e10 376 TIGRFAM TIGR03265 PhnT2: putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein 27 376 6.2E-156 T 14-10-2018 IPR017666 2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT2 GO:0005524 LH59_07740 f6e1896071d48781a2afb12e9b5b1e10 376 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_07740 f6e1896071d48781a2afb12e9b5b1e10 376 Pfam PF00005 ABC transporter 43 185 6.5E-35 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_04480 692d8b05fc210b682aabebcc0e840987 299 SUPERFAMILY SSF53850 90 297 7.78E-41 T 14-10-2018 LH59_04480 692d8b05fc210b682aabebcc0e840987 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 7.2E-14 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_04480 692d8b05fc210b682aabebcc0e840987 299 Pfam PF03466 LysR substrate binding domain 89 296 5.0E-39 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_04480 692d8b05fc210b682aabebcc0e840987 299 Gene3D G3DSA:3.40.190.290 93 298 6.2E-40 T 14-10-2018 LH59_04480 692d8b05fc210b682aabebcc0e840987 299 SUPERFAMILY SSF46785 2 112 5.28E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_04480 692d8b05fc210b682aabebcc0e840987 299 Gene3D G3DSA:1.10.10.10 3 92 7.7E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_06735 82b515e746a916e21a22cf1c4423707b 152 Gene3D G3DSA:3.40.630.30 2 147 3.8E-41 T 14-10-2018 LH59_06735 82b515e746a916e21a22cf1c4423707b 152 SUPERFAMILY SSF55729 1 149 1.03E-30 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_06735 82b515e746a916e21a22cf1c4423707b 152 Pfam PF13673 Acetyltransferase (GNAT) domain 46 148 2.3E-14 T 14-10-2018 IPR000182 GNAT domain LH59_15880 06baf30c281f7d9afa104f4b67ecb981 591 Pfam PF05199 GMC oxidoreductase 448 570 6.9E-20 T 14-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 LH59_15880 06baf30c281f7d9afa104f4b67ecb981 591 Gene3D G3DSA:3.50.50.60 6 132 5.5E-7 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_15880 06baf30c281f7d9afa104f4b67ecb981 591 SUPERFAMILY SSF51905 5 582 2.45E-48 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_15880 06baf30c281f7d9afa104f4b67ecb981 591 Gene3D G3DSA:3.50.50.60 478 583 6.5E-9 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_15880 06baf30c281f7d9afa104f4b67ecb981 591 Pfam PF00732 GMC oxidoreductase 233 345 1.1E-11 T 14-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 LH59_15880 06baf30c281f7d9afa104f4b67ecb981 591 Gene3D G3DSA:3.50.50.60 246 358 1.2E-11 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_15880 06baf30c281f7d9afa104f4b67ecb981 591 SUPERFAMILY SSF54373 434 492 1.26E-6 T 14-10-2018 LH59_22945 ea571c9c586803273be21090277a8bf8 376 Pfam PF05175 Methyltransferase small domain 194 313 2.6E-11 T 14-10-2018 IPR007848 Methyltransferase small domain GO:0008168 LH59_22945 ea571c9c586803273be21090277a8bf8 376 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 265 271 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 LH59_22945 ea571c9c586803273be21090277a8bf8 376 SUPERFAMILY SSF53335 165 314 2.54E-32 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_22945 ea571c9c586803273be21090277a8bf8 376 Gene3D G3DSA:3.40.50.150 186 369 1.4E-29 T 14-10-2018 LH59_03335 fe943b7aa84ac4cb1de5ac9684cbf2ca 404 Gene3D G3DSA:3.40.190.10 154 198 5.4E-51 T 14-10-2018 LH59_03335 fe943b7aa84ac4cb1de5ac9684cbf2ca 404 Gene3D G3DSA:3.40.190.170 279 378 2.6E-34 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily LH59_03335 fe943b7aa84ac4cb1de5ac9684cbf2ca 404 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 3 27 0.0013 T 14-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal LH59_03335 fe943b7aa84ac4cb1de5ac9684cbf2ca 404 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 265 363 3.2E-11 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 LH59_03335 fe943b7aa84ac4cb1de5ac9684cbf2ca 404 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 43 196 4.7E-20 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 LH59_03335 fe943b7aa84ac4cb1de5ac9684cbf2ca 404 Gene3D G3DSA:3.40.190.10 251 364 2.6E-34 T 14-10-2018 LH59_03335 fe943b7aa84ac4cb1de5ac9684cbf2ca 404 Gene3D G3DSA:3.40.190.170 34 153 5.4E-51 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily LH59_19665 a7420d29b0326bad79e815d6c9c29737 733 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 716 733 - T 14-10-2018 IPR010917 TonB-dependent receptor, conserved site LH59_19665 a7420d29b0326bad79e815d6c9c29737 733 SUPERFAMILY SSF56935 32 733 3.09E-107 T 14-10-2018 LH59_19665 a7420d29b0326bad79e815d6c9c29737 733 Pfam PF07715 TonB-dependent Receptor Plug Domain 74 172 5.0E-16 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_19665 a7420d29b0326bad79e815d6c9c29737 733 Gene3D G3DSA:2.170.130.10 68 188 9.7E-24 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily LH59_19665 a7420d29b0326bad79e815d6c9c29737 733 Gene3D G3DSA:2.40.170.20 193 733 2.6E-80 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_19665 a7420d29b0326bad79e815d6c9c29737 733 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 77 733 5.7E-111 T 14-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 LH59_19665 a7420d29b0326bad79e815d6c9c29737 733 Pfam PF00593 TonB dependent receptor 278 731 3.0E-41 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_18400 aff6a29ead5b708ccb5944a099054d80 617 Gene3D G3DSA:3.40.50.300 312 601 6.1E-86 T 14-10-2018 LH59_18400 aff6a29ead5b708ccb5944a099054d80 617 Gene3D G3DSA:3.40.50.300 10 293 5.2E-86 T 14-10-2018 LH59_18400 aff6a29ead5b708ccb5944a099054d80 617 SMART SM00382 41 246 6.4E-18 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_18400 aff6a29ead5b708ccb5944a099054d80 617 SMART SM00382 351 543 1.4E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_18400 aff6a29ead5b708ccb5944a099054d80 617 Pfam PF00005 ABC transporter 343 493 1.5E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_18400 aff6a29ead5b708ccb5944a099054d80 617 ProSitePatterns PS00211 ABC transporters family signature. 169 183 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_18400 aff6a29ead5b708ccb5944a099054d80 617 SUPERFAMILY SSF52540 316 566 4.41E-71 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_18400 aff6a29ead5b708ccb5944a099054d80 617 Pfam PF00005 ABC transporter 33 196 1.6E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_18400 aff6a29ead5b708ccb5944a099054d80 617 ProSitePatterns PS00211 ABC transporters family signature. 467 481 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_18400 aff6a29ead5b708ccb5944a099054d80 617 SUPERFAMILY SSF52540 12 268 3.06E-67 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_18400 aff6a29ead5b708ccb5944a099054d80 617 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 248 277 3.1E-8 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_18400 aff6a29ead5b708ccb5944a099054d80 617 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 546 591 1.1E-6 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_13145 2ac8a62b75d986c06930631a22b47814 303 Gene3D G3DSA:1.10.8.60 165 229 1.7E-20 T 14-10-2018 LH59_13145 2ac8a62b75d986c06930631a22b47814 303 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 206 215 - T 14-10-2018 IPR025944 Sigma-54 interaction domain, conserved site LH59_13145 2ac8a62b75d986c06930631a22b47814 303 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 80 95 - T 14-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 LH59_13145 2ac8a62b75d986c06930631a22b47814 303 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 18 31 - T 14-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 LH59_13145 2ac8a62b75d986c06930631a22b47814 303 Gene3D G3DSA:1.10.10.60 254 294 3.9E-9 T 14-10-2018 LH59_13145 2ac8a62b75d986c06930631a22b47814 303 Pfam PF00158 Sigma-54 interaction domain 1 160 1.6E-59 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 LH59_13145 2ac8a62b75d986c06930631a22b47814 303 SUPERFAMILY SSF46689 206 296 4.66E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_13145 2ac8a62b75d986c06930631a22b47814 303 SMART SM00382 14 157 1.4E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_13145 2ac8a62b75d986c06930631a22b47814 303 SUPERFAMILY SSF52540 1 227 4.76E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_13145 2ac8a62b75d986c06930631a22b47814 303 Pfam PF02954 Bacterial regulatory protein, Fis family 259 294 3.1E-7 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 LH59_13145 2ac8a62b75d986c06930631a22b47814 303 Gene3D G3DSA:3.40.50.300 1 164 8.3E-58 T 14-10-2018 LH59_22215 cb2defc751fe5b794b4b4c8ed84a41b4 146 Gene3D G3DSA:3.10.129.10 1 143 5.4E-40 T 14-10-2018 LH59_22215 cb2defc751fe5b794b4b4c8ed84a41b4 146 Pfam PF01575 MaoC like domain 15 108 1.2E-15 T 14-10-2018 IPR002539 MaoC-like dehydratase domain LH59_22215 cb2defc751fe5b794b4b4c8ed84a41b4 146 SUPERFAMILY SSF54637 2 141 2.75E-34 T 14-10-2018 IPR029069 HotDog domain superfamily LH59_06695 fad7e86e7aee31232224cc8b6d78908e 293 Gene3D G3DSA:1.20.120.530 157 293 6.4E-22 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_06695 fad7e86e7aee31232224cc8b6d78908e 293 Pfam PF07729 FCD domain 163 287 8.7E-17 T 14-10-2018 IPR011711 GntR, C-terminal LH59_06695 fad7e86e7aee31232224cc8b6d78908e 293 SMART SM00345 95 151 1.1 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_06695 fad7e86e7aee31232224cc8b6d78908e 293 SMART SM00345 16 74 1.2E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_06695 fad7e86e7aee31232224cc8b6d78908e 293 SUPERFAMILY SSF46785 94 153 8.16E-5 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_06695 fad7e86e7aee31232224cc8b6d78908e 293 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 74 5.8E-15 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_06695 fad7e86e7aee31232224cc8b6d78908e 293 Pfam PF00392 Bacterial regulatory proteins, gntR family 110 149 3.6E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_06695 fad7e86e7aee31232224cc8b6d78908e 293 SUPERFAMILY SSF46785 8 78 6.7E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_06695 fad7e86e7aee31232224cc8b6d78908e 293 Gene3D G3DSA:1.10.10.10 10 76 4.8E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_06695 fad7e86e7aee31232224cc8b6d78908e 293 Gene3D G3DSA:1.10.10.10 91 152 7.9E-8 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_06695 fad7e86e7aee31232224cc8b6d78908e 293 SUPERFAMILY SSF48008 160 291 1.73E-21 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_06695 fad7e86e7aee31232224cc8b6d78908e 293 SMART SM00895 163 288 4.1E-15 T 14-10-2018 IPR011711 GntR, C-terminal LH59_15910 3cb762cfe8a608b3fe466a052d9a5fec 344 Gene3D G3DSA:1.10.10.60 227 335 1.5E-23 T 14-10-2018 LH59_15910 3cb762cfe8a608b3fe466a052d9a5fec 344 Pfam PF12833 Helix-turn-helix domain 256 331 1.4E-16 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_15910 3cb762cfe8a608b3fe466a052d9a5fec 344 SMART SM00342 248 330 5.7E-17 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_15910 3cb762cfe8a608b3fe466a052d9a5fec 344 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 283 326 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 LH59_15910 3cb762cfe8a608b3fe466a052d9a5fec 344 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 314 330 1.1E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 LH59_15910 3cb762cfe8a608b3fe466a052d9a5fec 344 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 299 314 1.1E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 LH59_15910 3cb762cfe8a608b3fe466a052d9a5fec 344 SUPERFAMILY SSF46689 282 334 1.03E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_09090 652e3f50ea236b6d6ce1810457250b70 874 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 874 203.276 T 14-10-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 LH59_09090 652e3f50ea236b6d6ce1810457250b70 874 Gene3D G3DSA:3.10.310.40 762 871 2.7E-29 T 14-10-2018 LH59_09090 652e3f50ea236b6d6ce1810457250b70 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 278 294 5.8E-32 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 LH59_09090 652e3f50ea236b6d6ce1810457250b70 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 205 216 5.8E-32 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 LH59_09090 652e3f50ea236b6d6ce1810457250b70 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 74 85 5.8E-32 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 LH59_09090 652e3f50ea236b6d6ce1810457250b70 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 302 315 5.8E-32 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 LH59_09090 652e3f50ea236b6d6ce1810457250b70 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 232 245 5.8E-32 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 LH59_09090 652e3f50ea236b6d6ce1810457250b70 874 SUPERFAMILY SSF50447 451 550 7.91E-19 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily LH59_09090 652e3f50ea236b6d6ce1810457250b70 874 Gene3D G3DSA:2.40.30.130 457 550 8.4E-10 T 14-10-2018 LH59_09090 652e3f50ea236b6d6ce1810457250b70 874 Pfam PF01411 tRNA synthetases class II (A) 5 552 3.0E-223 T 14-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 LH59_09090 652e3f50ea236b6d6ce1810457250b70 874 SUPERFAMILY SSF101353 252 442 1.26E-59 T 14-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 LH59_09090 652e3f50ea236b6d6ce1810457250b70 874 SMART SM00863 651 693 5.5E-20 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 LH59_09090 652e3f50ea236b6d6ce1810457250b70 874 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 651 693 9.5E-17 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 LH59_09090 652e3f50ea236b6d6ce1810457250b70 874 Pfam PF02272 DHHA1 domain 731 870 2.0E-24 T 14-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 LH59_09090 652e3f50ea236b6d6ce1810457250b70 874 SUPERFAMILY SSF55186 550 708 1.83E-48 T 14-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 LH59_09090 652e3f50ea236b6d6ce1810457250b70 874 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 853 0.0 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 LH59_09090 652e3f50ea236b6d6ce1810457250b70 874 Gene3D G3DSA:3.30.980.10 560 694 2.9E-49 T 14-10-2018 LH59_09090 652e3f50ea236b6d6ce1810457250b70 874 SUPERFAMILY SSF55681 2 251 6.46E-108 T 14-10-2018 LH59_09090 652e3f50ea236b6d6ce1810457250b70 874 Gene3D G3DSA:3.30.930.10 1 248 6.2E-119 T 14-10-2018 LH59_09090 652e3f50ea236b6d6ce1810457250b70 874 Gene3D G3DSA:3.30.54.20 622 674 2.9E-49 T 14-10-2018 LH59_20000 295379ad8403c68458b4ebc0118a1339 430 Pfam PF04932 O-Antigen ligase 190 332 2.7E-13 T 14-10-2018 IPR007016 O-antigen ligase-related LH59_07340 afd20132ba74bc9611d2676a82b5a0dd 258 Pfam PF01614 Bacterial transcriptional regulator 122 237 6.1E-15 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal LH59_07340 afd20132ba74bc9611d2676a82b5a0dd 258 Gene3D G3DSA:3.30.450.40 75 245 4.8E-30 T 14-10-2018 IPR029016 GAF-like domain superfamily LH59_07340 afd20132ba74bc9611d2676a82b5a0dd 258 SMART SM00346 3 93 1.5E-6 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_07340 afd20132ba74bc9611d2676a82b5a0dd 258 SUPERFAMILY SSF55781 76 241 1.05E-28 T 14-10-2018 LH59_07340 afd20132ba74bc9611d2676a82b5a0dd 258 Pfam PF09339 IclR helix-turn-helix domain 6 53 3.7E-12 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_07340 afd20132ba74bc9611d2676a82b5a0dd 258 SUPERFAMILY SSF46785 3 75 1.17E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_07340 afd20132ba74bc9611d2676a82b5a0dd 258 Gene3D G3DSA:1.10.10.10 1 74 2.0E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_26990 a01c8fdd17750773bc799678ff0f4f25 578 PIRSF PIRSF029745 9 578 6.4E-117 T 14-10-2018 IPR027282 Two partner secretion pathway transporter GO:0015031 LH59_26990 a01c8fdd17750773bc799678ff0f4f25 578 Pfam PF03865 Haemolysin secretion/activation protein ShlB/FhaC/HecB 224 538 6.4E-87 T 14-10-2018 IPR005565 Haemolysin activator HlyB, C-terminal LH59_26990 a01c8fdd17750773bc799678ff0f4f25 578 Pfam PF08479 POTRA domain, ShlB-type 93 166 3.3E-12 T 14-10-2018 IPR013686 Polypeptide-transport-associated, ShlB-type LH59_26990 a01c8fdd17750773bc799678ff0f4f25 578 Pfam PF17287 POTRA domain 168 219 9.3E-11 T 14-10-2018 IPR035251 ShlB, POTRA domain LH59_26990 a01c8fdd17750773bc799678ff0f4f25 578 Gene3D G3DSA:2.40.160.50 197 578 5.7E-81 T 14-10-2018 LH59_12205 ca364d85428c8e26d491c05c5d46a21f 155 SUPERFAMILY SSF46785 4 63 1.24E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_12205 ca364d85428c8e26d491c05c5d46a21f 155 SUPERFAMILY SSF54909 66 153 2.95E-17 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel LH59_12205 ca364d85428c8e26d491c05c5d46a21f 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 3.0E-17 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_12205 ca364d85428c8e26d491c05c5d46a21f 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 3.0E-17 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_12205 ca364d85428c8e26d491c05c5d46a21f 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 3.0E-17 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_12205 ca364d85428c8e26d491c05c5d46a21f 155 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 50 3.3E-19 T 14-10-2018 LH59_12205 ca364d85428c8e26d491c05c5d46a21f 155 Gene3D G3DSA:3.30.70.920 56 149 1.7E-22 T 14-10-2018 LH59_12205 ca364d85428c8e26d491c05c5d46a21f 155 Gene3D G3DSA:1.10.10.10 1 55 5.4E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_12205 ca364d85428c8e26d491c05c5d46a21f 155 Pfam PF01037 Lrp/AsnC ligand binding domain 71 144 3.9E-18 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LH59_12205 ca364d85428c8e26d491c05c5d46a21f 155 SMART SM00344 4 113 4.6E-47 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 LH59_02185 9fb846e4f093779956f2ca2da0d63799 508 Gene3D G3DSA:3.30.750.190 293 412 5.0E-92 T 14-10-2018 LH59_02185 9fb846e4f093779956f2ca2da0d63799 508 Gene3D G3DSA:1.10.1040.50 191 495 5.0E-92 T 14-10-2018 LH59_02185 9fb846e4f093779956f2ca2da0d63799 508 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 6 184 1.9E-62 T 14-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 LH59_02185 9fb846e4f093779956f2ca2da0d63799 508 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 415 499 1.7E-20 T 14-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 LH59_02185 9fb846e4f093779956f2ca2da0d63799 508 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 187 284 6.6E-24 T 14-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 LH59_02185 9fb846e4f093779956f2ca2da0d63799 508 Gene3D G3DSA:3.40.50.720 2 190 2.6E-67 T 14-10-2018 LH59_02185 9fb846e4f093779956f2ca2da0d63799 508 SUPERFAMILY SSF51735 1 186 1.56E-54 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_02185 9fb846e4f093779956f2ca2da0d63799 508 SUPERFAMILY SSF48179 186 294 2.13E-26 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 LH59_02185 9fb846e4f093779956f2ca2da0d63799 508 SUPERFAMILY SSF48179 414 498 1.7E-19 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 LH59_20180 0673c9f6d6285ea7edfa02c244809ab2 306 SUPERFAMILY SSF53850 90 294 9.77E-49 T 14-10-2018 LH59_20180 0673c9f6d6285ea7edfa02c244809ab2 306 SUPERFAMILY SSF46785 7 112 5.44E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_20180 0673c9f6d6285ea7edfa02c244809ab2 306 Gene3D G3DSA:3.40.190.10 91 290 9.6E-69 T 14-10-2018 LH59_20180 0673c9f6d6285ea7edfa02c244809ab2 306 Gene3D G3DSA:3.40.190.10 163 264 9.6E-69 T 14-10-2018 LH59_20180 0673c9f6d6285ea7edfa02c244809ab2 306 Pfam PF03466 LysR substrate binding domain 89 293 1.5E-46 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_20180 0673c9f6d6285ea7edfa02c244809ab2 306 Gene3D G3DSA:1.10.10.10 3 88 3.5E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_20180 0673c9f6d6285ea7edfa02c244809ab2 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 3.2E-15 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_16455 ca6962375f237e5948b049ef7aa644b2 264 SUPERFAMILY SSF53474 12 258 7.03E-42 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_16455 ca6962375f237e5948b049ef7aa644b2 264 Pfam PF00561 alpha/beta hydrolase fold 34 151 9.6E-18 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_16455 ca6962375f237e5948b049ef7aa644b2 264 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 121 6.8E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_16455 ca6962375f237e5948b049ef7aa644b2 264 PRINTS PR00111 Alpha/beta hydrolase fold signature 122 135 6.8E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_16455 ca6962375f237e5948b049ef7aa644b2 264 PRINTS PR00111 Alpha/beta hydrolase fold signature 60 75 6.8E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_16455 ca6962375f237e5948b049ef7aa644b2 264 Gene3D G3DSA:3.40.50.1820 9 260 8.6E-41 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_13195 8249007c419d4b1d3f35845e9278812b 184 SUPERFAMILY SSF52317 8 179 2.58E-46 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_13195 8249007c419d4b1d3f35845e9278812b 184 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 10 178 1.3E-49 T 14-10-2018 IPR006286 Deglycase PfpI LH59_13195 8249007c419d4b1d3f35845e9278812b 184 Gene3D G3DSA:3.40.50.880 2 182 1.3E-53 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_13195 8249007c419d4b1d3f35845e9278812b 184 Pfam PF01965 DJ-1/PfpI family 10 177 3.3E-50 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 LH59_09205 234a34cac9a0543ab402cfd8c413a4a1 434 Pfam PF12221 Bacterial membrane protein N terminal 8 58 6.4E-11 T 14-10-2018 IPR020980 Menbrane protein HflK, N-terminal LH59_09205 234a34cac9a0543ab402cfd8c413a4a1 434 Gene3D G3DSA:3.30.479.30 157 265 1.4E-16 T 14-10-2018 LH59_09205 234a34cac9a0543ab402cfd8c413a4a1 434 TIGRFAM TIGR01933 hflK: HflK protein 101 376 2.1E-87 T 14-10-2018 IPR010201 HflK GO:0016021 LH59_09205 234a34cac9a0543ab402cfd8c413a4a1 434 SUPERFAMILY SSF117892 166 281 4.18E-18 T 14-10-2018 IPR036013 Band 7/SPFH domain superfamily LH59_09205 234a34cac9a0543ab402cfd8c413a4a1 434 SMART SM00244 99 274 1.2E-21 T 14-10-2018 IPR001107 Band 7 domain LH59_09205 234a34cac9a0543ab402cfd8c413a4a1 434 Pfam PF01145 SPFH domain / Band 7 family 103 289 5.6E-27 T 14-10-2018 IPR001107 Band 7 domain LH59_09155 5ac70c2a2e83ecfe1b0dd8ecf19f0ffc 384 Pfam PF04055 Radical SAM superfamily 110 293 8.0E-15 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 LH59_09155 5ac70c2a2e83ecfe1b0dd8ecf19f0ffc 384 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 5 367 1.1E-131 T 14-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 LH59_09155 5ac70c2a2e83ecfe1b0dd8ecf19f0ffc 384 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 6 362 71.879 T 14-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 LH59_09155 5ac70c2a2e83ecfe1b0dd8ecf19f0ffc 384 Gene3D G3DSA:3.20.20.70 69 347 1.4E-105 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_09155 5ac70c2a2e83ecfe1b0dd8ecf19f0ffc 384 PIRSF PIRSF006004 4 375 8.2E-143 T 14-10-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 LH59_09155 5ac70c2a2e83ecfe1b0dd8ecf19f0ffc 384 SUPERFAMILY SSF102114 104 331 1.09E-12 T 14-10-2018 LH59_09155 5ac70c2a2e83ecfe1b0dd8ecf19f0ffc 384 Gene3D G3DSA:1.10.150.530 6 67 4.4E-20 T 14-10-2018 LH59_22100 62026fb11b47628a70aba6317c806f18 317 Pfam PF03060 Nitronate monooxygenase 5 304 5.1E-59 T 14-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 LH59_22100 62026fb11b47628a70aba6317c806f18 317 Gene3D G3DSA:3.20.20.70 1 315 6.5E-97 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_22100 62026fb11b47628a70aba6317c806f18 317 SUPERFAMILY SSF51412 2 311 3.05E-62 T 14-10-2018 LH59_01695 3095943a4f5349ca21b044bed1e0336f 264 SUPERFAMILY SSF88713 26 252 4.17E-43 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 LH59_01695 3095943a4f5349ca21b044bed1e0336f 264 Gene3D G3DSA:3.20.20.370 26 256 4.6E-38 T 14-10-2018 LH59_01695 3095943a4f5349ca21b044bed1e0336f 264 Pfam PF01522 Polysaccharide deacetylase 28 177 1.4E-21 T 14-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 LH59_01825 339576327f6f5f60ac1f07531f5919a0 188 Pfam PF00117 Glutamine amidotransferase class-I 4 185 2.5E-54 T 14-10-2018 IPR017926 Glutamine amidotransferase LH59_01825 339576327f6f5f60ac1f07531f5919a0 188 SUPERFAMILY SSF52317 2 187 8.49E-57 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_01825 339576327f6f5f60ac1f07531f5919a0 188 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 186 2.3E-78 T 14-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 LH59_01825 339576327f6f5f60ac1f07531f5919a0 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 2.1E-13 T 14-10-2018 LH59_01825 339576327f6f5f60ac1f07531f5919a0 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 2.1E-13 T 14-10-2018 LH59_01825 339576327f6f5f60ac1f07531f5919a0 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 164 177 2.1E-13 T 14-10-2018 LH59_01825 339576327f6f5f60ac1f07531f5919a0 188 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 1.4E-6 T 14-10-2018 LH59_01825 339576327f6f5f60ac1f07531f5919a0 188 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 1.4E-6 T 14-10-2018 LH59_01825 339576327f6f5f60ac1f07531f5919a0 188 Gene3D G3DSA:3.40.50.880 1 188 2.7E-63 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_01825 339576327f6f5f60ac1f07531f5919a0 188 PRINTS PR00097 Anthranilate synthase component II signature 119 131 3.1E-33 T 14-10-2018 LH59_01825 339576327f6f5f60ac1f07531f5919a0 188 PRINTS PR00097 Anthranilate synthase component II signature 164 177 3.1E-33 T 14-10-2018 LH59_01825 339576327f6f5f60ac1f07531f5919a0 188 PRINTS PR00097 Anthranilate synthase component II signature 2 16 3.1E-33 T 14-10-2018 LH59_01825 339576327f6f5f60ac1f07531f5919a0 188 PRINTS PR00097 Anthranilate synthase component II signature 47 56 3.1E-33 T 14-10-2018 LH59_01825 339576327f6f5f60ac1f07531f5919a0 188 PRINTS PR00097 Anthranilate synthase component II signature 99 107 3.1E-33 T 14-10-2018 LH59_01825 339576327f6f5f60ac1f07531f5919a0 188 PRINTS PR00097 Anthranilate synthase component II signature 74 85 3.1E-33 T 14-10-2018 LH59_04845 5528c8322c1c56f42adbb6c06b3daf88 413 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 36 68 7.2E-13 T 14-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal LH59_04845 5528c8322c1c56f42adbb6c06b3daf88 413 SUPERFAMILY SSF50249 37 133 3.77E-19 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_04845 5528c8322c1c56f42adbb6c06b3daf88 413 SUPERFAMILY SSF51735 169 394 2.09E-35 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_04845 5528c8322c1c56f42adbb6c06b3daf88 413 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 241 252 3.1E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_04845 5528c8322c1c56f42adbb6c06b3daf88 413 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 342 359 3.1E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_04845 5528c8322c1c56f42adbb6c06b3daf88 413 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 3.1E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_04845 5528c8322c1c56f42adbb6c06b3daf88 413 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 321 340 3.1E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_04845 5528c8322c1c56f42adbb6c06b3daf88 413 Gene3D G3DSA:3.40.50.720 152 404 1.7E-36 T 14-10-2018 LH59_04845 5528c8322c1c56f42adbb6c06b3daf88 413 Pfam PF00106 short chain dehydrogenase 171 360 3.7E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_04845 5528c8322c1c56f42adbb6c06b3daf88 413 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 72 131 1.3E-6 T 14-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal LH59_23300 705c690db811984953b1421918b99a60 505 Gene3D G3DSA:1.20.80.10 416 505 1.9E-10 T 14-10-2018 IPR014352 FERM/acyl-CoA-binding protein superfamily LH59_23300 705c690db811984953b1421918b99a60 505 Gene3D G3DSA:3.40.50.1820 2 252 4.9E-44 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_23300 705c690db811984953b1421918b99a60 505 Gene3D G3DSA:3.10.450.50 272 396 2.6E-17 T 14-10-2018 LH59_23300 705c690db811984953b1421918b99a60 505 Pfam PF00887 Acyl CoA binding protein 424 501 3.7E-8 T 14-10-2018 IPR000582 Acyl-CoA-binding protein, ACBP GO:0000062 LH59_23300 705c690db811984953b1421918b99a60 505 SUPERFAMILY SSF47027 421 504 4.58E-12 T 14-10-2018 IPR035984 Acyl-CoA binding protein superfamily GO:0000062 LH59_23300 705c690db811984953b1421918b99a60 505 Pfam PF12146 Serine aminopeptidase, S33 8 238 2.9E-12 T 14-10-2018 IPR022742 Serine aminopeptidase, S33 LH59_23300 705c690db811984953b1421918b99a60 505 Pfam PF12680 SnoaL-like domain 276 379 6.4E-8 T 14-10-2018 IPR037401 SnoaL-like domain LH59_23300 705c690db811984953b1421918b99a60 505 SUPERFAMILY SSF54427 272 384 4.9E-13 T 14-10-2018 IPR032710 NTF2-like domain superfamily LH59_23300 705c690db811984953b1421918b99a60 505 SUPERFAMILY SSF53474 8 251 2.7E-31 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_13030 f01e0c9112512a44e1397b77d17eaf19 273 Gene3D G3DSA:3.40.190.10 35 259 6.7E-70 T 14-10-2018 LH59_13030 f01e0c9112512a44e1397b77d17eaf19 273 SUPERFAMILY SSF53850 34 263 2.76E-66 T 14-10-2018 LH59_13030 f01e0c9112512a44e1397b77d17eaf19 273 Gene3D G3DSA:3.40.190.10 115 219 6.7E-70 T 14-10-2018 LH59_13030 f01e0c9112512a44e1397b77d17eaf19 273 Pfam PF03180 NLPA lipoprotein 34 265 2.0E-66 T 14-10-2018 IPR004872 Lipoprotein NlpA family LH59_27930 48fe2c97463b912fb73a60f09064009a 156 PIRSF PIRSF002122 3 156 1.2E-58 T 14-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 LH59_27930 48fe2c97463b912fb73a60f09064009a 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 14-10-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27930 48fe2c97463b912fb73a60f09064009a 156 SUPERFAMILY SSF47973 2 149 2.22E-60 T 14-10-2018 IPR036823 Ribosomal protein S7 domain superfamily LH59_27930 48fe2c97463b912fb73a60f09064009a 156 Gene3D G3DSA:1.10.455.10 2 155 2.1E-59 T 14-10-2018 IPR036823 Ribosomal protein S7 domain superfamily LH59_27930 48fe2c97463b912fb73a60f09064009a 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 7.0E-66 T 14-10-2018 IPR023798 Ribosomal protein S7 domain LH59_27930 48fe2c97463b912fb73a60f09064009a 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 2.1E-66 T 14-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 LH59_27930 48fe2c97463b912fb73a60f09064009a 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 35.399 T 14-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 LH59_14545 b8091ab009ea6e7134cc63e5634c12ad 1251 TIGRFAM TIGR01580 narG: nitrate reductase, alpha subunit 2 1233 0.0 T 14-10-2018 IPR006468 Nitrate reductase, alpha subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 LH59_14545 b8091ab009ea6e7134cc63e5634c12ad 1251 SUPERFAMILY SSF53706 4 1067 0.0 T 14-10-2018 LH59_14545 b8091ab009ea6e7134cc63e5634c12ad 1251 Gene3D G3DSA:3.40.50.12440 44 1244 0.0 T 14-10-2018 LH59_14545 b8091ab009ea6e7134cc63e5634c12ad 1251 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 48 66 - T 14-10-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 LH59_14545 b8091ab009ea6e7134cc63e5634c12ad 1251 SMART SM00926 43 105 1.0E-8 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_14545 b8091ab009ea6e7134cc63e5634c12ad 1251 SUPERFAMILY SSF50692 1076 1235 1.72E-44 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily LH59_14545 b8091ab009ea6e7134cc63e5634c12ad 1251 Pfam PF00384 Molybdopterin oxidoreductase 108 829 2.0E-156 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_14545 b8091ab009ea6e7134cc63e5634c12ad 1251 Pfam PF14710 Respiratory nitrate reductase alpha N-terminal 3 40 1.2E-16 T 14-10-2018 IPR028189 Nitrate reductase, alpha subunit, N-terminal KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 LH59_14545 b8091ab009ea6e7134cc63e5634c12ad 1251 Pfam PF01568 Molydopterin dinucleotide binding domain 1086 1200 2.6E-20 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 LH59_04470 8363958cf38630eac4498f08d3d22826 286 SUPERFAMILY SSF54637 10 157 1.22E-45 T 14-10-2018 IPR029069 HotDog domain superfamily LH59_04470 8363958cf38630eac4498f08d3d22826 286 Pfam PF01575 MaoC like domain 162 260 3.8E-22 T 14-10-2018 IPR002539 MaoC-like dehydratase domain LH59_04470 8363958cf38630eac4498f08d3d22826 286 Gene3D G3DSA:3.10.129.10 14 286 3.2E-84 T 14-10-2018 LH59_04470 8363958cf38630eac4498f08d3d22826 286 SUPERFAMILY SSF54637 177 278 3.22E-25 T 14-10-2018 IPR029069 HotDog domain superfamily LH59_04470 8363958cf38630eac4498f08d3d22826 286 Pfam PF13452 N-terminal half of MaoC dehydratase 37 136 5.3E-12 T 14-10-2018 IPR039569 N-terminal of MaoC-like dehydratase Reactome: R-HSA-193368|Reactome: R-HSA-2046106|Reactome: R-HSA-389887|Reactome: R-HSA-390247|Reactome: R-HSA-9033241|Reactome: R-HSA-9033500 LH59_25560 6586d704493959996c96a955e4fdfadb 399 Pfam PF13458 Periplasmic binding protein 27 362 1.8E-83 T 14-10-2018 IPR028081 Leucine-binding protein domain LH59_25560 6586d704493959996c96a955e4fdfadb 399 SUPERFAMILY SSF53822 27 396 2.16E-84 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_25560 6586d704493959996c96a955e4fdfadb 399 Gene3D G3DSA:3.40.50.2300 146 277 5.2E-106 T 14-10-2018 LH59_25560 6586d704493959996c96a955e4fdfadb 399 Gene3D G3DSA:3.40.50.2300 27 328 5.2E-106 T 14-10-2018 LH59_14970 f31f855416f61758bb0f1bf3c2b9a5e5 268 Gene3D G3DSA:1.10.10.10 18 94 3.8E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_14970 f31f855416f61758bb0f1bf3c2b9a5e5 268 Pfam PF01614 Bacterial transcriptional regulator 142 259 5.6E-19 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal LH59_14970 f31f855416f61758bb0f1bf3c2b9a5e5 268 Pfam PF09339 IclR helix-turn-helix domain 21 73 1.0E-12 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_14970 f31f855416f61758bb0f1bf3c2b9a5e5 268 SMART SM00346 19 110 6.3E-16 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_14970 f31f855416f61758bb0f1bf3c2b9a5e5 268 SUPERFAMILY SSF46785 20 93 3.67E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_14970 f31f855416f61758bb0f1bf3c2b9a5e5 268 Gene3D G3DSA:3.30.450.40 95 267 4.1E-39 T 14-10-2018 IPR029016 GAF-like domain superfamily LH59_14970 f31f855416f61758bb0f1bf3c2b9a5e5 268 SUPERFAMILY SSF55781 85 263 2.09E-40 T 14-10-2018 LH59_17035 5f636954966d4af3921527c0d8cc4653 231 SMART SM00448 4 114 2.6E-41 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_17035 5f636954966d4af3921527c0d8cc4653 231 SMART SM00862 150 227 3.4E-20 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_17035 5f636954966d4af3921527c0d8cc4653 231 SUPERFAMILY SSF52172 3 176 2.42E-40 T 14-10-2018 IPR011006 CheY-like superfamily LH59_17035 5f636954966d4af3921527c0d8cc4653 231 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 227 8.8E-18 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_17035 5f636954966d4af3921527c0d8cc4653 231 Gene3D G3DSA:3.40.50.2300 1 123 4.4E-34 T 14-10-2018 LH59_17035 5f636954966d4af3921527c0d8cc4653 231 Pfam PF00072 Response regulator receiver domain 6 114 4.4E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_17035 5f636954966d4af3921527c0d8cc4653 231 Gene3D G3DSA:1.10.10.10 124 230 6.2E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_18300 02cbee38367d61877ac52046c4556f8b 157 Pfam PF02566 OsmC-like protein 52 146 2.3E-9 T 14-10-2018 IPR003718 OsmC/Ohr family LH59_18300 02cbee38367d61877ac52046c4556f8b 157 Gene3D G3DSA:3.30.300.20 1 150 5.2E-49 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta LH59_18300 02cbee38367d61877ac52046c4556f8b 157 SUPERFAMILY SSF82784 4 151 2.88E-44 T 14-10-2018 IPR036102 OsmC/Ohr superfamily LH59_21795 120aea89deda9e378c449809f8356cd6 315 SUPERFAMILY SSF46689 205 254 1.34E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_21795 120aea89deda9e378c449809f8356cd6 315 Pfam PF06719 AraC-type transcriptional regulator N-terminus 41 191 1.6E-46 T 14-10-2018 IPR009594 Transcription regulator HTH, AraC, N-terminal LH59_21795 120aea89deda9e378c449809f8356cd6 315 Pfam PF12833 Helix-turn-helix domain 227 301 1.7E-19 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_21795 120aea89deda9e378c449809f8356cd6 315 SUPERFAMILY SSF46689 257 307 2.2E-8 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_21795 120aea89deda9e378c449809f8356cd6 315 SMART SM00342 221 304 4.0E-24 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_21795 120aea89deda9e378c449809f8356cd6 315 Gene3D G3DSA:1.10.10.60 200 309 1.2E-26 T 14-10-2018 LH59_23895 d39b310a38af29ba0cf7be1e75f2a9bb 614 SUPERFAMILY SSF103190 89 172 7.85E-9 T 14-10-2018 IPR029151 Periplasmic sensor-like domain superfamily LH59_23895 d39b310a38af29ba0cf7be1e75f2a9bb 614 Gene3D G3DSA:1.10.287.950 295 599 9.2E-80 T 14-10-2018 LH59_23895 d39b310a38af29ba0cf7be1e75f2a9bb 614 SMART SM00304 295 349 3.5E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_23895 d39b310a38af29ba0cf7be1e75f2a9bb 614 Pfam PF02743 Cache domain 104 257 7.3E-17 T 14-10-2018 IPR033479 Double Cache domain 1 LH59_23895 d39b310a38af29ba0cf7be1e75f2a9bb 614 Gene3D G3DSA:3.30.450.20 54 268 2.1E-41 T 14-10-2018 LH59_23895 d39b310a38af29ba0cf7be1e75f2a9bb 614 SUPERFAMILY SSF58104 317 598 7.72E-69 T 14-10-2018 LH59_23895 d39b310a38af29ba0cf7be1e75f2a9bb 614 Gene3D G3DSA:3.30.450.20 65 167 2.1E-41 T 14-10-2018 LH59_23895 d39b310a38af29ba0cf7be1e75f2a9bb 614 SMART SM00283 350 597 3.6E-77 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 LH59_23895 d39b310a38af29ba0cf7be1e75f2a9bb 614 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 409 564 3.9E-51 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 LH59_23895 d39b310a38af29ba0cf7be1e75f2a9bb 614 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 525 554 1.7E-45 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_23895 d39b310a38af29ba0cf7be1e75f2a9bb 614 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 448 475 1.7E-45 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_23895 d39b310a38af29ba0cf7be1e75f2a9bb 614 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 477 506 1.7E-45 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_23895 d39b310a38af29ba0cf7be1e75f2a9bb 614 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 371 400 1.7E-45 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_12520 5ac901948c39cb9c6343f54c9cd52157 303 SUPERFAMILY SSF53850 90 295 9.31E-36 T 14-10-2018 LH59_12520 5ac901948c39cb9c6343f54c9cd52157 303 Pfam PF03466 LysR substrate binding domain 90 284 1.2E-37 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_12520 5ac901948c39cb9c6343f54c9cd52157 303 Gene3D G3DSA:3.40.190.10 164 267 1.9E-26 T 14-10-2018 LH59_12520 5ac901948c39cb9c6343f54c9cd52157 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 2.9E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_12520 5ac901948c39cb9c6343f54c9cd52157 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 2.9E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_12520 5ac901948c39cb9c6343f54c9cd52157 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 2.9E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_12520 5ac901948c39cb9c6343f54c9cd52157 303 Gene3D G3DSA:1.10.10.10 1 89 2.3E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_12520 5ac901948c39cb9c6343f54c9cd52157 303 Gene3D G3DSA:3.40.190.10 91 274 1.9E-26 T 14-10-2018 LH59_12520 5ac901948c39cb9c6343f54c9cd52157 303 SUPERFAMILY SSF46785 1 110 5.54E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_12520 5ac901948c39cb9c6343f54c9cd52157 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 1.3E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_06940 18b154bc9fb5480afd06a52032341c95 685 Pfam PF03169 OPT oligopeptide transporter protein 15 639 1.7E-105 T 14-10-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 LH59_06940 18b154bc9fb5480afd06a52032341c95 685 TIGRFAM TIGR00733 TIGR00733: oligopeptide transporter, OPT family 15 640 2.0E-212 T 14-10-2018 IPR004814 Oligopeptide transporter OPT LH59_06940 18b154bc9fb5480afd06a52032341c95 685 TIGRFAM TIGR00728 OPT_sfam: oligopeptide transporter, OPT superfamily 8 639 3.3E-113 T 14-10-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 LH59_13170 b291d2fcf3fd19d3f5cfa99aa4bf817b 212 Pfam PF13628 Domain of unknown function (DUF4142) 33 169 1.9E-28 T 14-10-2018 IPR025419 Domain of unknown function DUF4142 LH59_04680 bab2bd7e340ac4d84f4cf56323f5cef1 291 SUPERFAMILY SSF51197 6 287 1.47E-72 T 14-10-2018 LH59_04680 bab2bd7e340ac4d84f4cf56323f5cef1 291 Gene3D G3DSA:3.60.130.10 2 290 3.3E-75 T 14-10-2018 LH59_04680 bab2bd7e340ac4d84f4cf56323f5cef1 291 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 10 279 2.6E-59 T 14-10-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 LH59_22590 3a19558c35f5d4d35f3e6c9fc3646942 336 PIRSF PIRSF000149 1 336 6.5E-135 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_22590 3a19558c35f5d4d35f3e6c9fc3646942 336 Gene3D G3DSA:3.40.50.720 4 327 2.3E-151 T 14-10-2018 LH59_22590 3a19558c35f5d4d35f3e6c9fc3646942 336 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 160 315 3.2E-63 T 14-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_22590 3a19558c35f5d4d35f3e6c9fc3646942 336 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 153 160 - T 14-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_22590 3a19558c35f5d4d35f3e6c9fc3646942 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 232 249 1.3E-39 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_22590 3a19558c35f5d4d35f3e6c9fc3646942 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 149 167 1.3E-39 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_22590 3a19558c35f5d4d35f3e6c9fc3646942 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 272 287 1.3E-39 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_22590 3a19558c35f5d4d35f3e6c9fc3646942 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 112 125 1.3E-39 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_22590 3a19558c35f5d4d35f3e6c9fc3646942 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 176 192 1.3E-39 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_22590 3a19558c35f5d4d35f3e6c9fc3646942 336 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 327 7.8E-128 T 14-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_22590 3a19558c35f5d4d35f3e6c9fc3646942 336 SUPERFAMILY SSF55347 155 316 1.37E-69 T 14-10-2018 LH59_22590 3a19558c35f5d4d35f3e6c9fc3646942 336 SMART SM00846 3 155 1.8E-93 T 14-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_22590 3a19558c35f5d4d35f3e6c9fc3646942 336 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 106 7.9E-39 T 14-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_22590 3a19558c35f5d4d35f3e6c9fc3646942 336 SUPERFAMILY SSF51735 3 176 1.41E-64 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_22590 3a19558c35f5d4d35f3e6c9fc3646942 336 Gene3D G3DSA:3.30.360.10 154 317 2.3E-151 T 14-10-2018 LH59_02570 7ba401caca134749129cf52ecac71a22 221 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 215 5.4E-19 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_02570 7ba401caca134749129cf52ecac71a22 221 SUPERFAMILY SSF161098 12 214 1.44E-43 T 14-10-2018 IPR035906 MetI-like superfamily LH59_02570 7ba401caca134749129cf52ecac71a22 221 Gene3D G3DSA:1.10.3720.10 1 217 3.2E-53 T 14-10-2018 IPR035906 MetI-like superfamily LH59_02570 7ba401caca134749129cf52ecac71a22 221 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 110 6.6E-24 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 LH59_26545 7482cd0300c99f4116c352e5382e6644 1320 SUPERFAMILY SSF56176 156 425 3.69E-53 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 LH59_26545 7482cd0300c99f4116c352e5382e6644 1320 Pfam PF11880 Domain of unknown function (DUF3400) 1276 1320 1.3E-24 T 14-10-2018 IPR021817 Protein of unknown function DUF3400 LH59_26545 7482cd0300c99f4116c352e5382e6644 1320 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 917 928 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site LH59_26545 7482cd0300c99f4116c352e5382e6644 1320 SUPERFAMILY SSF46548 825 947 3.14E-13 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 LH59_26545 7482cd0300c99f4116c352e5382e6644 1320 Pfam PF02913 FAD linked oxidases, C-terminal domain 459 576 0.0015 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 LH59_26545 7482cd0300c99f4116c352e5382e6644 1320 Pfam PF02913 FAD linked oxidases, C-terminal domain 719 816 1.3E-17 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 LH59_26545 7482cd0300c99f4116c352e5382e6644 1320 Gene3D G3DSA:3.30.70.2740 712 780 1.5E-6 T 14-10-2018 LH59_26545 7482cd0300c99f4116c352e5382e6644 1320 Gene3D G3DSA:3.30.465.40 154 357 1.1E-34 T 14-10-2018 LH59_26545 7482cd0300c99f4116c352e5382e6644 1320 Pfam PF01565 FAD binding domain 194 339 2.7E-26 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 LH59_26545 7482cd0300c99f4116c352e5382e6644 1320 SUPERFAMILY SSF55103 458 818 4.86E-38 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 LH59_26545 7482cd0300c99f4116c352e5382e6644 1320 Pfam PF13183 4Fe-4S dicluster domain 853 931 8.4E-7 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain LH59_26545 7482cd0300c99f4116c352e5382e6644 1320 Pfam PF02754 Cysteine-rich domain 1062 1151 4.9E-7 T 14-10-2018 IPR004017 Cysteine-rich domain LH59_26545 7482cd0300c99f4116c352e5382e6644 1320 Pfam PF02754 Cysteine-rich domain 1187 1273 0.0042 T 14-10-2018 IPR004017 Cysteine-rich domain LH59_26545 7482cd0300c99f4116c352e5382e6644 1320 Pfam PF12447 Protein of unknown function (DUF3683) 21 144 5.7E-50 T 14-10-2018 IPR022153 Protein of unknown function DUF3683 LH59_23665 bfd2fe8f2ae96d5daf6f773e16900344 763 SUPERFAMILY SSF56935 98 762 3.21E-126 T 14-10-2018 LH59_23665 bfd2fe8f2ae96d5daf6f773e16900344 763 Gene3D G3DSA:3.55.50.30 14 114 1.5E-22 T 14-10-2018 LH59_23665 bfd2fe8f2ae96d5daf6f773e16900344 763 Pfam PF07715 TonB-dependent Receptor Plug Domain 133 236 2.0E-20 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_23665 bfd2fe8f2ae96d5daf6f773e16900344 763 Gene3D G3DSA:2.40.170.20 246 763 7.8E-128 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_23665 bfd2fe8f2ae96d5daf6f773e16900344 763 Pfam PF07660 Secretin and TonB N terminus short domain 47 92 3.7E-8 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 LH59_23665 bfd2fe8f2ae96d5daf6f773e16900344 763 Gene3D G3DSA:2.170.130.10 115 245 1.0E-34 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily LH59_23665 bfd2fe8f2ae96d5daf6f773e16900344 763 Pfam PF00593 TonB dependent receptor 334 761 1.5E-54 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_23665 bfd2fe8f2ae96d5daf6f773e16900344 763 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 134 760 1.3E-111 T 14-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 LH59_23665 bfd2fe8f2ae96d5daf6f773e16900344 763 SMART SM00965 45 95 8.0E-11 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 LH59_14665 152df98fecabdfcef090ead9ce2e493e 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 7.2E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_14665 152df98fecabdfcef090ead9ce2e493e 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 7.2E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_14665 152df98fecabdfcef090ead9ce2e493e 200 Gene3D G3DSA:1.10.357.10 1 200 6.4E-42 T 14-10-2018 LH59_14665 152df98fecabdfcef090ead9ce2e493e 200 SUPERFAMILY SSF46689 3 65 4.54E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_14665 152df98fecabdfcef090ead9ce2e493e 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 57 1.8E-14 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_14665 152df98fecabdfcef090ead9ce2e493e 200 SUPERFAMILY SSF48498 83 193 8.53E-12 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily LH59_14720 95e314f8e79df708a37ad30d101090bc 183 SUPERFAMILY SSF47240 19 173 1.07E-44 T 14-10-2018 IPR009078 Ferritin-like superfamily LH59_14720 95e314f8e79df708a37ad30d101090bc 183 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 57 73 1.2E-7 T 14-10-2018 IPR002177 DNA-binding protein Dps LH59_14720 95e314f8e79df708a37ad30d101090bc 183 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 153 171 1.2E-7 T 14-10-2018 IPR002177 DNA-binding protein Dps LH59_14720 95e314f8e79df708a37ad30d101090bc 183 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 81 97 1.2E-7 T 14-10-2018 IPR002177 DNA-binding protein Dps LH59_14720 95e314f8e79df708a37ad30d101090bc 183 Pfam PF00210 Ferritin-like domain 38 171 2.9E-25 T 14-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 LH59_14720 95e314f8e79df708a37ad30d101090bc 183 PIRSF PIRSF005900 14 180 8.7E-49 T 14-10-2018 IPR002177 DNA-binding protein Dps LH59_14720 95e314f8e79df708a37ad30d101090bc 183 Gene3D G3DSA:1.20.1260.10 9 175 2.8E-45 T 14-10-2018 IPR012347 Ferritin-like LH59_03635 36154637c6484f8c073c7b4a9cf4b706 402 TIGRFAM TIGR00210 gltS: sodium/glutamate symporter 4 397 1.4E-117 T 14-10-2018 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 LH59_03635 36154637c6484f8c073c7b4a9cf4b706 402 Pfam PF03616 Sodium/glutamate symporter 3 366 6.2E-111 T 14-10-2018 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 LH59_03635 36154637c6484f8c073c7b4a9cf4b706 402 Hamap MF_02062 Sodium/glutamate symporter [gltS]. 2 397 21.022 T 14-10-2018 IPR004445 Sodium/glutamate symport carrier protein GltS GO:0015501|GO:0015813|GO:0016021 LH59_07375 e58ca91746c45c93d7bc0cb0ee49de0b 604 SUPERFAMILY SSF53383 134 527 8.6E-47 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_07375 e58ca91746c45c93d7bc0cb0ee49de0b 604 Gene3D G3DSA:3.90.1150.10 51 546 3.4E-210 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_07375 e58ca91746c45c93d7bc0cb0ee49de0b 604 Pfam PF00155 Aminotransferase class I and II 204 529 6.9E-25 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LH59_07375 e58ca91746c45c93d7bc0cb0ee49de0b 604 Gene3D G3DSA:1.10.20.110 57 425 3.4E-210 T 14-10-2018 LH59_07375 e58ca91746c45c93d7bc0cb0ee49de0b 604 Gene3D G3DSA:3.40.640.10 179 403 3.4E-210 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_07375 e58ca91746c45c93d7bc0cb0ee49de0b 604 TIGRFAM TIGR03801 asp_4_decarbox: aspartate 4-decarboxylase 28 548 1.8E-226 T 14-10-2018 IPR022518 Aspartate 4-decarboxylase KEGG: 00220+2.6.1.1|KEGG: 00250+4.1.1.12+2.6.1.1|KEGG: 00270+4.1.1.12+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 LH59_27660 d7f3dbc6d8b47d6ca94848e452560906 815 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 85 735 5.3E-178 T 14-10-2018 LH59_27660 d7f3dbc6d8b47d6ca94848e452560906 815 Pfam PF17092 Penicillin-binding protein OB-like domain 340 448 6.4E-17 T 14-10-2018 IPR031376 Penicillin-binding protein, OB-like domain KEGG: 00550+2.4.1.129+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 LH59_27660 d7f3dbc6d8b47d6ca94848e452560906 815 Gene3D G3DSA:1.10.3810.10 69 266 8.5E-74 T 14-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 LH59_27660 d7f3dbc6d8b47d6ca94848e452560906 815 SUPERFAMILY SSF53955 62 271 1.07E-73 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily LH59_27660 d7f3dbc6d8b47d6ca94848e452560906 815 Gene3D G3DSA:3.40.710.10 383 760 2.3E-106 T 14-10-2018 LH59_27660 d7f3dbc6d8b47d6ca94848e452560906 815 Pfam PF00905 Penicillin binding protein transpeptidase domain 451 726 3.1E-40 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 LH59_27660 d7f3dbc6d8b47d6ca94848e452560906 815 Pfam PF00912 Transglycosylase 76 249 3.1E-61 T 14-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 LH59_27660 d7f3dbc6d8b47d6ca94848e452560906 815 SUPERFAMILY SSF56601 231 758 3.42E-117 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like LH59_20070 df5ab874b59fcf98b5bbc70d796be3dd 399 Gene3D G3DSA:3.40.47.10 10 282 1.2E-139 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_20070 df5ab874b59fcf98b5bbc70d796be3dd 399 PIRSF PIRSF000429 2 399 1.1E-125 T 14-10-2018 IPR002155 Thiolase GO:0016747 LH59_20070 df5ab874b59fcf98b5bbc70d796be3dd 399 ProSitePatterns PS00737 Thiolases signature 2. 345 361 - T 14-10-2018 IPR020613 Thiolase, conserved site GO:0016747 LH59_20070 df5ab874b59fcf98b5bbc70d796be3dd 399 Pfam PF00108 Thiolase, N-terminal domain 9 268 1.8E-69 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 LH59_20070 df5ab874b59fcf98b5bbc70d796be3dd 399 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 10 397 1.2E-136 T 14-10-2018 IPR002155 Thiolase GO:0016747 LH59_20070 df5ab874b59fcf98b5bbc70d796be3dd 399 Gene3D G3DSA:3.40.47.10 132 395 1.2E-139 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_20070 df5ab874b59fcf98b5bbc70d796be3dd 399 SUPERFAMILY SSF53901 7 276 8.65E-71 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_20070 df5ab874b59fcf98b5bbc70d796be3dd 399 SUPERFAMILY SSF53901 278 397 3.9E-43 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_20070 df5ab874b59fcf98b5bbc70d796be3dd 399 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 90 108 - T 14-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 LH59_20070 df5ab874b59fcf98b5bbc70d796be3dd 399 Pfam PF02803 Thiolase, C-terminal domain 277 397 8.0E-45 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 LH59_20070 df5ab874b59fcf98b5bbc70d796be3dd 399 ProSitePatterns PS00099 Thiolases active site. 380 393 - T 14-10-2018 IPR020610 Thiolase, active site GO:0016747 LH59_01320 12c270647c4f7c82caafbc5287d9fe91 378 Gene3D G3DSA:3.40.50.10800 127 350 2.1E-91 T 14-10-2018 LH59_01320 12c270647c4f7c82caafbc5287d9fe91 378 Gene3D G3DSA:3.40.50.10800 44 332 2.1E-91 T 14-10-2018 LH59_01320 12c270647c4f7c82caafbc5287d9fe91 378 Gene3D G3DSA:3.40.50.10800 212 307 2.1E-91 T 14-10-2018 LH59_01320 12c270647c4f7c82caafbc5287d9fe91 378 Pfam PF02445 Quinolinate synthetase A protein 44 350 6.1E-100 T 14-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 LH59_01320 12c270647c4f7c82caafbc5287d9fe91 378 SUPERFAMILY SSF142754 42 351 3.92E-104 T 14-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 LH59_01320 12c270647c4f7c82caafbc5287d9fe91 378 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 41 351 3.7E-104 T 14-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 LH59_08515 f9865a313ecc34f3f87c70f9225086e8 265 SUPERFAMILY SSF74653 184 261 3.79E-20 T 14-10-2018 LH59_08515 f9865a313ecc34f3f87c70f9225086e8 265 PRINTS PR01374 Gram-negative bacterial tonB protein signature 120 130 2.1E-8 T 14-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 LH59_08515 f9865a313ecc34f3f87c70f9225086e8 265 PRINTS PR01374 Gram-negative bacterial tonB protein signature 181 202 2.1E-8 T 14-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 LH59_08515 f9865a313ecc34f3f87c70f9225086e8 265 PRINTS PR01374 Gram-negative bacterial tonB protein signature 202 220 2.1E-8 T 14-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 LH59_08515 f9865a313ecc34f3f87c70f9225086e8 265 Gene3D G3DSA:3.30.1150.10 167 263 2.8E-18 T 14-10-2018 LH59_08515 f9865a313ecc34f3f87c70f9225086e8 265 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 187 263 4.5E-22 T 14-10-2018 IPR006260 TonB/TolA, C-terminal LH59_08515 f9865a313ecc34f3f87c70f9225086e8 265 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 187 262 6.8E-21 T 14-10-2018 IPR037682 TonB, C-terminal GO:0055085 LH59_06400 39f29d3e4084cb10a5c8be6b0447c291 277 Pfam PF06167 Glucose-regulated metallo-peptidase M90 17 269 8.6E-77 T 14-10-2018 IPR010384 MtfA family LH59_06400 39f29d3e4084cb10a5c8be6b0447c291 277 SUPERFAMILY SSF55486 44 271 4.39E-37 T 14-10-2018 LH59_06400 39f29d3e4084cb10a5c8be6b0447c291 277 Gene3D G3DSA:3.40.390.10 148 277 1.2E-33 T 14-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 LH59_06400 39f29d3e4084cb10a5c8be6b0447c291 277 Gene3D G3DSA:1.10.472.150 23 147 1.6E-42 T 14-10-2018 LH59_18990 2e8e20ad11a059e1d34cdd8c799ab2cf 184 SUPERFAMILY SSF47413 2 67 7.6E-18 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 LH59_18990 2e8e20ad11a059e1d34cdd8c799ab2cf 184 SUPERFAMILY SSF51182 75 181 6.11E-24 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_18990 2e8e20ad11a059e1d34cdd8c799ab2cf 184 Gene3D G3DSA:2.60.120.10 74 182 5.1E-27 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_18990 2e8e20ad11a059e1d34cdd8c799ab2cf 184 Gene3D G3DSA:1.10.260.40 3 73 2.8E-18 T 14-10-2018 LH59_18990 2e8e20ad11a059e1d34cdd8c799ab2cf 184 Pfam PF07883 Cupin domain 127 181 3.4E-14 T 14-10-2018 IPR013096 Cupin 2, conserved barrel LH59_18990 2e8e20ad11a059e1d34cdd8c799ab2cf 184 Pfam PF01381 Helix-turn-helix 8 60 2.2E-16 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LH59_18990 2e8e20ad11a059e1d34cdd8c799ab2cf 184 SMART SM00530 7 62 4.5E-17 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LH59_24560 af2eb32332f6c6c147bda0309535e42b 189 SUPERFAMILY SSF89392 18 188 4.32E-29 T 14-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX LH59_24560 af2eb32332f6c6c147bda0309535e42b 189 Gene3D G3DSA:2.50.20.10 28 188 2.8E-28 T 14-10-2018 LH59_24560 af2eb32332f6c6c147bda0309535e42b 189 Pfam PF03550 Outer membrane lipoprotein LolB 33 188 3.1E-32 T 14-10-2018 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 LH59_24560 af2eb32332f6c6c147bda0309535e42b 189 TIGRFAM TIGR00548 lolB: outer membrane lipoprotein LolB 50 164 9.9E-20 T 14-10-2018 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 LH59_24560 af2eb32332f6c6c147bda0309535e42b 189 Hamap MF_00233 Outer-membrane lipoprotein LolB [lolB]. 2 189 19.827 T 14-10-2018 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 LH59_11400 5349686eed4bfd3c52c4562d5c659e79 139 Pfam PF00460 Flagella basal body rod protein 7 37 1.2E-9 T 14-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 LH59_11400 5349686eed4bfd3c52c4562d5c659e79 139 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 91 135 1.0E-14 T 14-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain LH59_11400 5349686eed4bfd3c52c4562d5c659e79 139 TIGRFAM TIGR01395 FlgC: flagellar basal-body rod protein FlgC 4 138 2.0E-53 T 14-10-2018 IPR006299 Flagellar basal-body rod protein FlgC GO:0030694|GO:0071973 LH59_11400 5349686eed4bfd3c52c4562d5c659e79 139 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 13 33 - T 14-10-2018 IPR019776 Flagellar basal body rod protein, conserved site LH59_00600 d4a69150857c4896ef2f5049cd778966 355 Pfam PF00753 Metallo-beta-lactamase superfamily 42 267 3.4E-23 T 14-10-2018 IPR001279 Metallo-beta-lactamase LH59_00600 d4a69150857c4896ef2f5049cd778966 355 Gene3D G3DSA:3.60.15.10 22 295 2.0E-52 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like LH59_00600 d4a69150857c4896ef2f5049cd778966 355 Gene3D G3DSA:1.10.10.10 298 347 1.4E-6 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_00600 d4a69150857c4896ef2f5049cd778966 355 SMART SM00849 42 267 1.8E-22 T 14-10-2018 IPR001279 Metallo-beta-lactamase LH59_00600 d4a69150857c4896ef2f5049cd778966 355 SUPERFAMILY SSF56281 15 350 3.28E-69 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like LH59_03355 6f9049444a2dbe88f09243d1f09c51ae 262 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_03355 6f9049444a2dbe88f09243d1f09c51ae 262 Pfam PF00005 ABC transporter 17 178 1.7E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_03355 6f9049444a2dbe88f09243d1f09c51ae 262 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 226 248 4.6E-11 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal LH59_03355 6f9049444a2dbe88f09243d1f09c51ae 262 SUPERFAMILY SSF52540 2 249 9.89E-69 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_03355 6f9049444a2dbe88f09243d1f09c51ae 262 SMART SM00382 26 225 1.3E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_03355 6f9049444a2dbe88f09243d1f09c51ae 262 Gene3D G3DSA:3.40.50.300 1 258 4.8E-68 T 14-10-2018 LH59_07785 ce03d48424979b8d373129400c117076 88 Pfam PF02609 Exonuclease VII small subunit 20 70 1.5E-20 T 14-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 LH59_07785 ce03d48424979b8d373129400c117076 88 Gene3D G3DSA:1.10.287.1040 13 88 1.9E-30 T 14-10-2018 IPR037004 Exonuclease VII, small subunit superfamily GO:0006308|GO:0008855|GO:0009318 LH59_07785 ce03d48424979b8d373129400c117076 88 SUPERFAMILY SSF116842 17 80 9.55E-20 T 14-10-2018 LH59_07785 ce03d48424979b8d373129400c117076 88 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 20 60 7.0E-14 T 14-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 LH59_07785 ce03d48424979b8d373129400c117076 88 PIRSF PIRSF006488 6 88 2.3E-23 T 14-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 LH59_07785 ce03d48424979b8d373129400c117076 88 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 19 73 2.2E-22 T 14-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 LH59_07785 ce03d48424979b8d373129400c117076 88 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 19 79 14.954 T 14-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 LH59_00515 987b618043953c87278261d07ea8c63c 702 Gene3D G3DSA:3.40.50.261 135 291 8.0E-43 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 LH59_00515 987b618043953c87278261d07ea8c63c 702 SUPERFAMILY SSF51735 1 133 1.43E-33 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_00515 987b618043953c87278261d07ea8c63c 702 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 152 288 2.2E-42 T 14-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain LH59_00515 987b618043953c87278261d07ea8c63c 702 SMART SM00881 1 96 2.4E-33 T 14-10-2018 IPR003781 CoA-binding GO:0048037 LH59_00515 987b618043953c87278261d07ea8c63c 702 SUPERFAMILY SSF56059 478 693 1.06E-27 T 14-10-2018 LH59_00515 987b618043953c87278261d07ea8c63c 702 Pfam PF13549 ATP-grasp domain 475 690 6.9E-47 T 14-10-2018 LH59_00515 987b618043953c87278261d07ea8c63c 702 Pfam PF13380 CoA binding domain 6 129 4.4E-22 T 14-10-2018 IPR003781 CoA-binding GO:0048037 LH59_00515 987b618043953c87278261d07ea8c63c 702 Gene3D G3DSA:3.40.50.261 292 452 1.9E-27 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 LH59_00515 987b618043953c87278261d07ea8c63c 702 Gene3D G3DSA:3.40.50.720 1 125 4.6E-39 T 14-10-2018 LH59_00515 987b618043953c87278261d07ea8c63c 702 SUPERFAMILY SSF52210 128 290 2.09E-37 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 LH59_00515 987b618043953c87278261d07ea8c63c 702 Gene3D G3DSA:3.30.1490.20 496 571 5.2E-57 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 LH59_00515 987b618043953c87278261d07ea8c63c 702 Gene3D G3DSA:3.30.470.20 477 688 5.2E-57 T 14-10-2018 LH59_00515 987b618043953c87278261d07ea8c63c 702 SUPERFAMILY SSF52210 295 451 3.27E-24 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 LH59_03140 e713438f3afc8b7b74601fe6483e78e2 828 SMART SM00388 238 303 3.5E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_03140 e713438f3afc8b7b74601fe6483e78e2 828 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 399 1.0E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_03140 e713438f3afc8b7b74601fe6483e78e2 828 PRINTS PR00344 Bacterial sensor protein C-terminal signature 442 455 1.0E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_03140 e713438f3afc8b7b74601fe6483e78e2 828 PRINTS PR00344 Bacterial sensor protein C-terminal signature 418 436 1.0E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_03140 e713438f3afc8b7b74601fe6483e78e2 828 SUPERFAMILY SSF55874 292 458 6.16E-31 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_03140 e713438f3afc8b7b74601fe6483e78e2 828 SUPERFAMILY SSF53850 508 780 1.43E-40 T 14-10-2018 LH59_03140 e713438f3afc8b7b74601fe6483e78e2 828 Pfam PF00512 His Kinase A (phospho-acceptor) domain 239 301 1.4E-10 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_03140 e713438f3afc8b7b74601fe6483e78e2 828 Pfam PF08521 Two-component sensor kinase N-terminal 24 162 9.7E-34 T 14-10-2018 IPR013727 Two-component sensor kinase, N-terminal LH59_03140 e713438f3afc8b7b74601fe6483e78e2 828 Gene3D G3DSA:3.30.565.10 306 456 1.4E-30 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_03140 e713438f3afc8b7b74601fe6483e78e2 828 SUPERFAMILY SSF47384 221 298 9.22E-14 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 LH59_03140 e713438f3afc8b7b74601fe6483e78e2 828 Gene3D G3DSA:3.40.190.10 508 805 1.0E-115 T 14-10-2018 LH59_03140 e713438f3afc8b7b74601fe6483e78e2 828 Gene3D G3DSA:3.40.190.10 603 817 1.0E-115 T 14-10-2018 LH59_03140 e713438f3afc8b7b74601fe6483e78e2 828 Gene3D G3DSA:1.10.287.130 190 302 2.2E-14 T 14-10-2018 LH59_03140 e713438f3afc8b7b74601fe6483e78e2 828 Pfam PF13531 Bacterial extracellular solute-binding protein 509 764 3.5E-16 T 14-10-2018 LH59_03140 e713438f3afc8b7b74601fe6483e78e2 828 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 348 457 1.3E-19 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_03140 e713438f3afc8b7b74601fe6483e78e2 828 SMART SM00387 348 458 6.1E-30 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_01745 d8ff01cbe84229fd1cf1f4ddf02a5db0 645 SUPERFAMILY SSF46785 511 573 1.24E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_01745 d8ff01cbe84229fd1cf1f4ddf02a5db0 645 SUPERFAMILY SSF50465 272 368 8.63E-20 T 14-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal LH59_01745 d8ff01cbe84229fd1cf1f4ddf02a5db0 645 Gene3D G3DSA:1.10.10.2770 440 572 1.4E-24 T 14-10-2018 LH59_01745 d8ff01cbe84229fd1cf1f4ddf02a5db0 645 Gene3D G3DSA:3.40.50.300 13 175 1.3E-41 T 14-10-2018 LH59_01745 d8ff01cbe84229fd1cf1f4ddf02a5db0 645 Pfam PF00009 Elongation factor Tu GTP binding domain 2 131 2.0E-26 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_01745 d8ff01cbe84229fd1cf1f4ddf02a5db0 645 SUPERFAMILY SSF50447 174 264 1.25E-16 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily LH59_01745 d8ff01cbe84229fd1cf1f4ddf02a5db0 645 SUPERFAMILY SSF52540 2 194 5.18E-36 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_01745 d8ff01cbe84229fd1cf1f4ddf02a5db0 645 PRINTS PR00315 GTP-binding elongation factor signature 54 64 3.0E-5 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_01745 d8ff01cbe84229fd1cf1f4ddf02a5db0 645 PRINTS PR00315 GTP-binding elongation factor signature 2 15 3.0E-5 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_01745 d8ff01cbe84229fd1cf1f4ddf02a5db0 645 PRINTS PR00315 GTP-binding elongation factor signature 70 81 3.0E-5 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_01745 d8ff01cbe84229fd1cf1f4ddf02a5db0 645 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 26 41 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site LH59_01745 d8ff01cbe84229fd1cf1f4ddf02a5db0 645 Gene3D G3DSA:2.40.30.10 176 291 1.5E-26 T 14-10-2018 LH59_01745 d8ff01cbe84229fd1cf1f4ddf02a5db0 645 SUPERFAMILY SSF46785 583 633 4.81E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_01745 d8ff01cbe84229fd1cf1f4ddf02a5db0 645 Pfam PF09107 Elongation factor SelB, winged helix 587 631 2.5E-18 T 14-10-2018 IPR015191 Translation elongation factor SelB, winged helix, type 3 GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 LH59_01745 d8ff01cbe84229fd1cf1f4ddf02a5db0 645 Pfam PF09106 Elongation factor SelB, winged helix 449 503 1.0E-14 T 14-10-2018 IPR015190 Translation elongation factor SelB, winged helix, type 2 GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 LH59_01745 d8ff01cbe84229fd1cf1f4ddf02a5db0 645 SUPERFAMILY SSF46785 438 507 3.54E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_01745 d8ff01cbe84229fd1cf1f4ddf02a5db0 645 TIGRFAM TIGR00475 selB: selenocysteine-specific translation elongation factor 1 632 1.7E-129 T 14-10-2018 IPR004535 Translation elongation factor, selenocysteine-specific GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 LH59_01745 d8ff01cbe84229fd1cf1f4ddf02a5db0 645 Gene3D G3DSA:1.10.10.10 573 633 2.3E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_06725 3894714d043ac1beb6494a000970b254 232 SMART SM00882 5 217 4.1E-94 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 LH59_06725 3894714d043ac1beb6494a000970b254 232 Pfam PF01144 Coenzyme A transferase 6 217 3.2E-80 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 LH59_06725 3894714d043ac1beb6494a000970b254 232 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 18 33 - T 14-10-2018 IPR004163 Coenzyme A transferase binding site GO:0008410 Reactome: R-HSA-77108 LH59_06725 3894714d043ac1beb6494a000970b254 232 SUPERFAMILY SSF100950 2 226 1.57E-89 T 14-10-2018 IPR037171 NagB/RpiA transferase-like LH59_06725 3894714d043ac1beb6494a000970b254 232 Gene3D G3DSA:3.40.1080.10 1 227 8.6E-98 T 14-10-2018 LH59_06725 3894714d043ac1beb6494a000970b254 232 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 1 217 3.3E-80 T 14-10-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 LH59_10385 6bc7d9c370888566a86aa1df69d4fa89 287 Gene3D G3DSA:2.60.120.10 17 279 1.8E-84 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_10385 6bc7d9c370888566a86aa1df69d4fa89 287 Pfam PF02678 Pirin 20 127 2.4E-35 T 14-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 LH59_10385 6bc7d9c370888566a86aa1df69d4fa89 287 PIRSF PIRSF006232 2 287 8.7E-90 T 14-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 LH59_10385 6bc7d9c370888566a86aa1df69d4fa89 287 Pfam PF05726 Pirin C-terminal cupin domain 182 283 3.5E-28 T 14-10-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 LH59_10385 6bc7d9c370888566a86aa1df69d4fa89 287 Gene3D G3DSA:2.60.120.10 149 253 1.8E-84 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_10385 6bc7d9c370888566a86aa1df69d4fa89 287 SUPERFAMILY SSF51182 2 286 6.86E-84 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_21695 13bd253e13a83df2fe0110059338baa6 349 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 35 318 2.4E-109 T 14-10-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 LH59_21695 13bd253e13a83df2fe0110059338baa6 349 Pfam PF00005 ABC transporter 20 162 6.7E-38 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_21695 13bd253e13a83df2fe0110059338baa6 349 Gene3D G3DSA:2.40.50.940 221 344 1.2E-14 T 14-10-2018 LH59_21695 13bd253e13a83df2fe0110059338baa6 349 SUPERFAMILY SSF52540 4 245 4.78E-88 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_21695 13bd253e13a83df2fe0110059338baa6 349 Pfam PF08402 TOBE domain 274 344 3.0E-12 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 LH59_21695 13bd253e13a83df2fe0110059338baa6 349 SUPERFAMILY SSF50331 239 346 6.8E-16 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal LH59_21695 13bd253e13a83df2fe0110059338baa6 349 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_21695 13bd253e13a83df2fe0110059338baa6 349 Gene3D G3DSA:3.40.50.300 1 217 2.0E-70 T 14-10-2018 LH59_21695 13bd253e13a83df2fe0110059338baa6 349 Gene3D G3DSA:2.40.50.140 280 337 1.2E-14 T 14-10-2018 LH59_21695 13bd253e13a83df2fe0110059338baa6 349 SMART SM00382 29 212 3.2E-23 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_17115 ef084ce927baa7b1c67efeaf88ce69cc 384 SUPERFAMILY SSF53901 3 384 2.81E-66 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_17115 ef084ce927baa7b1c67efeaf88ce69cc 384 Pfam PF02803 Thiolase, C-terminal domain 262 383 1.3E-36 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 LH59_17115 ef084ce927baa7b1c67efeaf88ce69cc 384 Gene3D G3DSA:3.40.47.10 127 381 2.2E-125 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_17115 ef084ce927baa7b1c67efeaf88ce69cc 384 PIRSF PIRSF000429 1 384 7.1E-109 T 14-10-2018 IPR002155 Thiolase GO:0016747 LH59_17115 ef084ce927baa7b1c67efeaf88ce69cc 384 Pfam PF00108 Thiolase, N-terminal domain 5 253 1.2E-59 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 LH59_17115 ef084ce927baa7b1c67efeaf88ce69cc 384 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 382 3.2E-117 T 14-10-2018 IPR002155 Thiolase GO:0016747 LH59_17115 ef084ce927baa7b1c67efeaf88ce69cc 384 Gene3D G3DSA:3.40.47.10 6 267 2.2E-125 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_17115 ef084ce927baa7b1c67efeaf88ce69cc 384 ProSitePatterns PS00737 Thiolases signature 2. 330 346 - T 14-10-2018 IPR020613 Thiolase, conserved site GO:0016747 LH59_21360 9b41bd09a6c04e410c78d6de3c9b65dd 337 SUPERFAMILY SSF47203 184 318 3.38E-28 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 LH59_21360 9b41bd09a6c04e410c78d6de3c9b65dd 337 SUPERFAMILY SSF56645 5 92 1.55E-8 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 LH59_21360 9b41bd09a6c04e410c78d6de3c9b65dd 337 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 5 76 1.3E-4 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 LH59_21360 9b41bd09a6c04e410c78d6de3c9b65dd 337 Gene3D G3DSA:1.20.140.10 178 327 7.2E-25 T 14-10-2018 LH59_21360 9b41bd09a6c04e410c78d6de3c9b65dd 337 Gene3D G3DSA:1.10.540.10 2 98 2.0E-11 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 LH59_21360 9b41bd09a6c04e410c78d6de3c9b65dd 337 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 185 306 8.9E-18 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LH59_27730 1ee80096358708fd0e4951cb4051d93f 207 Gene3D G3DSA:1.10.1050.10 6 207 1.1E-78 T 14-10-2018 LH59_27730 1ee80096358708fd0e4951cb4051d93f 207 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 207 34.738 T 14-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 LH59_27730 1ee80096358708fd0e4951cb4051d93f 207 Gene3D G3DSA:3.10.290.10 96 192 1.1E-78 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 LH59_27730 1ee80096358708fd0e4951cb4051d93f 207 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 207 2.4E-78 T 14-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 LH59_27730 1ee80096358708fd0e4951cb4051d93f 207 ProSitePatterns PS00632 Ribosomal protein S4 signature. 95 119 - T 14-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27730 1ee80096358708fd0e4951cb4051d93f 207 SMART SM00363 97 161 3.5E-16 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27730 1ee80096358708fd0e4951cb4051d93f 207 SUPERFAMILY SSF55174 3 207 1.18E-66 T 14-10-2018 LH59_27730 1ee80096358708fd0e4951cb4051d93f 207 SMART SM01390 3 96 6.2E-49 T 14-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 LH59_27730 1ee80096358708fd0e4951cb4051d93f 207 Pfam PF01479 S4 domain 98 144 6.1E-17 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27730 1ee80096358708fd0e4951cb4051d93f 207 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 96 6.3E-32 T 14-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 LH59_10185 370f63bbea4278895255d8576e7dc09e 452 Gene3D G3DSA:3.30.390.30 337 452 1.9E-42 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 LH59_10185 370f63bbea4278895255d8576e7dc09e 452 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 14-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 LH59_10185 370f63bbea4278895255d8576e7dc09e 452 TIGRFAM TIGR01424 gluta_reduc_2: glutathione-disulfide reductase 3 447 2.6E-184 T 14-10-2018 IPR006324 Glutathione-disulphide reductase GO:0004362|GO:0006749|GO:0050660|GO:0050661|GO:0055114 KEGG: 00480+1.8.1.7|MetaCyc: PWY-4081 LH59_10185 370f63bbea4278895255d8576e7dc09e 452 Gene3D G3DSA:3.50.50.60 5 317 6.8E-116 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_10185 370f63bbea4278895255d8576e7dc09e 452 SUPERFAMILY SSF55424 335 448 3.09E-36 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 LH59_10185 370f63bbea4278895255d8576e7dc09e 452 PIRSF PIRSF000350 2 443 3.3E-83 T 14-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 LH59_10185 370f63bbea4278895255d8576e7dc09e 452 SUPERFAMILY SSF51905 2 324 1.3E-60 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_10185 370f63bbea4278895255d8576e7dc09e 452 Gene3D G3DSA:3.50.50.60 143 260 6.8E-116 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_10185 370f63bbea4278895255d8576e7dc09e 452 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 317 1.1E-70 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LH59_10185 370f63bbea4278895255d8576e7dc09e 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 421 441 8.9E-68 T 14-10-2018 LH59_10185 370f63bbea4278895255d8576e7dc09e 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 8.9E-68 T 14-10-2018 LH59_10185 370f63bbea4278895255d8576e7dc09e 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 399 414 8.9E-68 T 14-10-2018 LH59_10185 370f63bbea4278895255d8576e7dc09e 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 297 304 8.9E-68 T 14-10-2018 LH59_10185 370f63bbea4278895255d8576e7dc09e 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 334 355 8.9E-68 T 14-10-2018 LH59_10185 370f63bbea4278895255d8576e7dc09e 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 254 268 8.9E-68 T 14-10-2018 LH59_10185 370f63bbea4278895255d8576e7dc09e 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 8.9E-68 T 14-10-2018 LH59_10185 370f63bbea4278895255d8576e7dc09e 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 134 143 8.9E-68 T 14-10-2018 LH59_10185 370f63bbea4278895255d8576e7dc09e 452 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 168 193 8.9E-68 T 14-10-2018 LH59_10185 370f63bbea4278895255d8576e7dc09e 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 269 1.2E-29 T 14-10-2018 LH59_10185 370f63bbea4278895255d8576e7dc09e 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 168 186 1.2E-29 T 14-10-2018 LH59_10185 370f63bbea4278895255d8576e7dc09e 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 131 149 1.2E-29 T 14-10-2018 LH59_10185 370f63bbea4278895255d8576e7dc09e 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.2E-29 T 14-10-2018 LH59_10185 370f63bbea4278895255d8576e7dc09e 452 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 282 304 1.2E-29 T 14-10-2018 LH59_10185 370f63bbea4278895255d8576e7dc09e 452 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 338 446 1.2E-35 T 14-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 LH59_21340 75bca95163679d2f0654dfa2faef7f82 249 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 62 2.9E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_21340 75bca95163679d2f0654dfa2faef7f82 249 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 32 46 2.9E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_21340 75bca95163679d2f0654dfa2faef7f82 249 SUPERFAMILY SSF46785 1 76 8.67E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_21340 75bca95163679d2f0654dfa2faef7f82 249 Pfam PF07729 FCD domain 82 205 1.3E-26 T 14-10-2018 IPR011711 GntR, C-terminal LH59_21340 75bca95163679d2f0654dfa2faef7f82 249 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 72 3.3E-16 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_21340 75bca95163679d2f0654dfa2faef7f82 249 SUPERFAMILY SSF48008 78 213 7.59E-27 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_21340 75bca95163679d2f0654dfa2faef7f82 249 Gene3D G3DSA:1.10.10.10 7 74 2.8E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_21340 75bca95163679d2f0654dfa2faef7f82 249 SMART SM00895 82 206 1.3E-19 T 14-10-2018 IPR011711 GntR, C-terminal LH59_21340 75bca95163679d2f0654dfa2faef7f82 249 SMART SM00345 14 72 3.2E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_21340 75bca95163679d2f0654dfa2faef7f82 249 Gene3D G3DSA:1.20.120.530 75 215 9.4E-29 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_11495 95ad0762fbcd19dfb3a2fce75c3235ab 335 SUPERFAMILY SSF101801 251 326 4.19E-12 T 14-10-2018 IPR036429 SpoA-like superfamily LH59_11495 95ad0762fbcd19dfb3a2fce75c3235ab 335 TIGRFAM TIGR01397 fliM_switch: flagellar motor switch protein FliM 6 322 6.2E-101 T 14-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 LH59_11495 95ad0762fbcd19dfb3a2fce75c3235ab 335 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 254 321 1.1E-16 T 14-10-2018 IPR001543 Surface presentation of antigen (SpoA) LH59_11495 95ad0762fbcd19dfb3a2fce75c3235ab 335 PRINTS PR00955 Flagellar motor switch protein FliM signature 115 134 6.6E-27 T 14-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 LH59_11495 95ad0762fbcd19dfb3a2fce75c3235ab 335 PRINTS PR00955 Flagellar motor switch protein FliM signature 213 231 6.6E-27 T 14-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 LH59_11495 95ad0762fbcd19dfb3a2fce75c3235ab 335 PRINTS PR00955 Flagellar motor switch protein FliM signature 4 17 6.6E-27 T 14-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 LH59_11495 95ad0762fbcd19dfb3a2fce75c3235ab 335 PRINTS PR00955 Flagellar motor switch protein FliM signature 90 106 6.6E-27 T 14-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 LH59_11495 95ad0762fbcd19dfb3a2fce75c3235ab 335 PIRSF PIRSF002888 3 332 3.4E-91 T 14-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 LH59_11495 95ad0762fbcd19dfb3a2fce75c3235ab 335 Pfam PF02154 Flagellar motor switch protein FliM 39 231 5.3E-71 T 14-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 LH59_11495 95ad0762fbcd19dfb3a2fce75c3235ab 335 Gene3D G3DSA:3.40.1550.10 45 233 2.9E-56 T 14-10-2018 IPR028976 CheC-like superfamily LH59_11495 95ad0762fbcd19dfb3a2fce75c3235ab 335 SUPERFAMILY SSF103039 51 231 1.07E-19 T 14-10-2018 IPR028976 CheC-like superfamily LH59_01710 1ededa9046f2321436686e9380559498 515 Pfam PF06863 Protein of unknown function (DUF1254) 76 204 4.7E-37 T 14-10-2018 IPR010679 Domain of unknown function DUF1254 LH59_01710 1ededa9046f2321436686e9380559498 515 Gene3D G3DSA:2.60.120.600 313 471 3.8E-36 T 14-10-2018 IPR037049 Domain of unknown function DUF1214, C-terminal domain superfamily LH59_01710 1ededa9046f2321436686e9380559498 515 SUPERFAMILY SSF160935 18 469 5.75E-111 T 14-10-2018 LH59_01710 1ededa9046f2321436686e9380559498 515 Pfam PF06742 Protein of unknown function (DUF1214) 352 454 2.7E-31 T 14-10-2018 IPR010621 Domain of unknown function DUF1214 LH59_26580 8ee049036f56d2f594c7d87eb9ad91b4 565 ProSitePatterns PS00211 ABC transporters family signature. 479 493 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_26580 8ee049036f56d2f594c7d87eb9ad91b4 565 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 7 536 1.9E-120 T 14-10-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0016021|GO:0034775|GO:0042626|GO:0045454 LH59_26580 8ee049036f56d2f594c7d87eb9ad91b4 565 Gene3D G3DSA:1.20.1560.10 1 325 5.6E-31 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 LH59_26580 8ee049036f56d2f594c7d87eb9ad91b4 565 SMART SM00382 367 555 5.9E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_26580 8ee049036f56d2f594c7d87eb9ad91b4 565 SUPERFAMILY SSF52540 329 557 1.29E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_26580 8ee049036f56d2f594c7d87eb9ad91b4 565 Pfam PF00664 ABC transporter transmembrane region 56 273 1.9E-14 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 LH59_26580 8ee049036f56d2f594c7d87eb9ad91b4 565 Pfam PF00005 ABC transporter 358 507 9.1E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_26580 8ee049036f56d2f594c7d87eb9ad91b4 565 Gene3D G3DSA:3.40.50.300 332 565 3.0E-63 T 14-10-2018 LH59_26580 8ee049036f56d2f594c7d87eb9ad91b4 565 SUPERFAMILY SSF90123 7 321 1.29E-39 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 LH59_11085 41d29b51f6d8697b63240176518cd4d3 134 Gene3D G3DSA:3.30.1300.30 47 130 1.8E-10 T 14-10-2018 LH59_11085 41d29b51f6d8697b63240176518cd4d3 134 TIGRFAM TIGR01707 gspI: type II secretion system protein I 19 115 1.3E-18 T 14-10-2018 IPR010052 Type II secretion system protein I GO:0008565|GO:0015627|GO:0015628 LH59_11085 41d29b51f6d8697b63240176518cd4d3 134 SUPERFAMILY SSF54523 20 65 8.16E-6 T 14-10-2018 LH59_11085 41d29b51f6d8697b63240176518cd4d3 134 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 17 40 6.7E-10 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site LH59_11085 41d29b51f6d8697b63240176518cd4d3 134 Pfam PF07963 Prokaryotic N-terminal methylation motif 16 40 3.2E-11 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site LH59_11085 41d29b51f6d8697b63240176518cd4d3 134 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 18 38 - T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site LH59_11085 41d29b51f6d8697b63240176518cd4d3 134 Pfam PF02501 Type II secretion system (T2SS), protein I 53 130 2.6E-17 T 14-10-2018 IPR003413 Type II secretion system protein I domain GO:0008565|GO:0015627|GO:0015628 LH59_11085 41d29b51f6d8697b63240176518cd4d3 134 SUPERFAMILY SSF54523 52 126 3.14E-11 T 14-10-2018 LH59_14475 3621700cf71238a2713b633fee10120a 341 SMART SM00062 36 266 5.3E-42 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_14475 3621700cf71238a2713b633fee10120a 341 SUPERFAMILY SSF53850 27 257 7.25E-46 T 14-10-2018 LH59_14475 3621700cf71238a2713b633fee10120a 341 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 37 255 1.8E-27 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_14475 3621700cf71238a2713b633fee10120a 341 Gene3D G3DSA:3.40.190.10 128 224 9.1E-50 T 14-10-2018 LH59_14475 3621700cf71238a2713b633fee10120a 341 Gene3D G3DSA:3.40.190.10 27 256 9.1E-50 T 14-10-2018 LH59_06765 54f4dc858ed814d371424c8b36fd595f 300 Gene3D G3DSA:1.10.3720.10 87 294 1.8E-22 T 14-10-2018 IPR035906 MetI-like superfamily LH59_06765 54f4dc858ed814d371424c8b36fd595f 300 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 23 74 2.9E-13 T 14-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain LH59_06765 54f4dc858ed814d371424c8b36fd595f 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 298 3.0E-29 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_06765 54f4dc858ed814d371424c8b36fd595f 300 SUPERFAMILY SSF161098 92 282 6.54E-29 T 14-10-2018 IPR035906 MetI-like superfamily LH59_26575 76dba2b30aac7e01b5522bbfa83a134c 183 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 10 178 1.4E-68 T 14-10-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 LH59_26575 76dba2b30aac7e01b5522bbfa83a134c 183 Gene3D G3DSA:3.40.50.2020 1 181 5.4E-66 T 14-10-2018 LH59_26575 76dba2b30aac7e01b5522bbfa83a134c 183 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 9 178 37.338 T 14-10-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 LH59_26575 76dba2b30aac7e01b5522bbfa83a134c 183 Pfam PF00156 Phosphoribosyl transferase domain 50 158 1.1E-17 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 LH59_26575 76dba2b30aac7e01b5522bbfa83a134c 183 SUPERFAMILY SSF53271 10 179 1.57E-54 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like LH59_11900 0e1a06fb579702f85c861f108cf26c83 155 Pfam PF01037 Lrp/AsnC ligand binding domain 78 142 3.7E-11 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LH59_11900 0e1a06fb579702f85c861f108cf26c83 155 Gene3D G3DSA:1.10.10.10 13 61 4.0E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_11900 0e1a06fb579702f85c861f108cf26c83 155 ProSitePatterns PS00519 AsnC-type HTH domain signature. 30 56 - T 14-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site LH59_11900 0e1a06fb579702f85c861f108cf26c83 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 12 28 4.7E-14 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_11900 0e1a06fb579702f85c861f108cf26c83 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 39 58 4.7E-14 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_11900 0e1a06fb579702f85c861f108cf26c83 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 39 4.7E-14 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_11900 0e1a06fb579702f85c861f108cf26c83 155 Pfam PF13412 Winged helix-turn-helix DNA-binding 12 59 1.7E-14 T 14-10-2018 LH59_11900 0e1a06fb579702f85c861f108cf26c83 155 Gene3D G3DSA:3.30.70.920 62 149 1.4E-17 T 14-10-2018 LH59_11900 0e1a06fb579702f85c861f108cf26c83 155 SUPERFAMILY SSF54909 74 144 3.49E-12 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel LH59_11900 0e1a06fb579702f85c861f108cf26c83 155 SUPERFAMILY SSF46785 11 72 2.91E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_11900 0e1a06fb579702f85c861f108cf26c83 155 SMART SM00344 12 118 3.4E-30 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 LH59_16375 def446efb5ee7886790dc4931e23d9ee 381 SUPERFAMILY SSF51395 5 379 8.55E-97 T 14-10-2018 LH59_16375 def446efb5ee7886790dc4931e23d9ee 381 Pfam PF01070 FMN-dependent dehydrogenase 16 379 7.3E-128 T 14-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 LH59_16375 def446efb5ee7886790dc4931e23d9ee 381 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 276 282 - T 14-10-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 Reactome: R-HSA-9033241 LH59_16375 def446efb5ee7886790dc4931e23d9ee 381 PIRSF PIRSF000138 1 381 7.3E-133 T 14-10-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 Reactome: R-HSA-9033241 LH59_16375 def446efb5ee7886790dc4931e23d9ee 381 Gene3D G3DSA:3.20.20.70 4 381 2.8E-129 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_11520 c9136df79cdb8aaae29c97f7867ebc62 247 PRINTS PR01003 Flagellar assembly protein FliH signature 198 214 4.5E-16 T 14-10-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 LH59_11520 c9136df79cdb8aaae29c97f7867ebc62 247 PRINTS PR01003 Flagellar assembly protein FliH signature 215 240 4.5E-16 T 14-10-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 LH59_11520 c9136df79cdb8aaae29c97f7867ebc62 247 PRINTS PR01003 Flagellar assembly protein FliH signature 129 146 4.5E-16 T 14-10-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 LH59_11520 c9136df79cdb8aaae29c97f7867ebc62 247 PRINTS PR01003 Flagellar assembly protein FliH signature 67 89 4.5E-16 T 14-10-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 LH59_11520 c9136df79cdb8aaae29c97f7867ebc62 247 PRINTS PR01003 Flagellar assembly protein FliH signature 170 197 4.5E-16 T 14-10-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 LH59_11520 c9136df79cdb8aaae29c97f7867ebc62 247 PRINTS PR01003 Flagellar assembly protein FliH signature 90 108 4.5E-16 T 14-10-2018 IPR000563 Flagellar assembly protein FliH GO:0003774|GO:0009288|GO:0071973 LH59_11520 c9136df79cdb8aaae29c97f7867ebc62 247 Pfam PF02108 Flagellar assembly protein FliH 107 233 7.8E-39 T 14-10-2018 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE LH59_12410 a6e9d5ce704636ad2140d5dc0b79eb70 66 Gene3D G3DSA:3.30.70.100 1 64 6.1E-22 T 14-10-2018 LH59_12410 a6e9d5ce704636ad2140d5dc0b79eb70 66 SUPERFAMILY SSF55008 2 64 1.17E-15 T 14-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 LH59_12410 a6e9d5ce704636ad2140d5dc0b79eb70 66 Pfam PF00403 Heavy-metal-associated domain 5 62 1.6E-12 T 14-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 LH59_12410 a6e9d5ce704636ad2140d5dc0b79eb70 66 ProSitePatterns PS01047 Heavy-metal-associated domain. 7 36 - T 14-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 LH59_18200 eec11eaf219a5321f57edee21044177c 242 SMART SM00100 24 145 2.7E-7 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain LH59_18200 eec11eaf219a5321f57edee21044177c 242 Pfam PF00027 Cyclic nucleotide-binding domain 44 126 4.0E-11 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain LH59_18200 eec11eaf219a5321f57edee21044177c 242 Gene3D G3DSA:2.60.120.10 37 157 1.4E-32 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_18200 eec11eaf219a5321f57edee21044177c 242 SUPERFAMILY SSF51206 17 156 5.76E-24 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like LH59_18200 eec11eaf219a5321f57edee21044177c 242 Gene3D G3DSA:1.10.10.10 159 240 3.3E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_18200 eec11eaf219a5321f57edee21044177c 242 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 203 218 1.1E-11 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 LH59_18200 eec11eaf219a5321f57edee21044177c 242 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 187 203 1.1E-11 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 LH59_18200 eec11eaf219a5321f57edee21044177c 242 SMART SM00419 181 229 5.7E-17 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 LH59_18200 eec11eaf219a5321f57edee21044177c 242 Pfam PF13545 Crp-like helix-turn-helix domain 162 236 4.6E-20 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 LH59_18200 eec11eaf219a5321f57edee21044177c 242 SUPERFAMILY SSF46785 161 239 5.44E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_18200 eec11eaf219a5321f57edee21044177c 242 ProSitePatterns PS00042 Crp-type HTH domain signature. 189 212 - T 14-10-2018 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 LH59_13120 c7b0c8fbfe950aa6d8871abb96ee2d02 99 Pfam PF05247 Flagellar transcriptional activator (FlhD) 5 84 6.3E-12 T 14-10-2018 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 LH59_13120 c7b0c8fbfe950aa6d8871abb96ee2d02 99 Gene3D G3DSA:1.10.4000.10 3 83 1.3E-13 T 14-10-2018 IPR036194 Flagellar transcriptional activator FlhD superfamily LH59_13120 c7b0c8fbfe950aa6d8871abb96ee2d02 99 SUPERFAMILY SSF63592 5 82 2.22E-11 T 14-10-2018 IPR036194 Flagellar transcriptional activator FlhD superfamily LH59_17925 815f820b30ffd219b1679d0033f6e1d3 192 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 157 164 - T 14-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 LH59_17925 815f820b30ffd219b1679d0033f6e1d3 192 SUPERFAMILY SSF46609 1 83 2.62E-36 T 14-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 LH59_17925 815f820b30ffd219b1679d0033f6e1d3 192 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 81 1.2E-34 T 14-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 LH59_17925 815f820b30ffd219b1679d0033f6e1d3 192 Gene3D G3DSA:2.40.500.20 83 192 1.3E-43 T 14-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 LH59_17925 815f820b30ffd219b1679d0033f6e1d3 192 Gene3D G3DSA:1.10.287.990 20 82 2.0E-26 T 14-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 LH59_17925 815f820b30ffd219b1679d0033f6e1d3 192 PIRSF PIRSF000349 1 192 1.5E-86 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 LH59_17925 815f820b30ffd219b1679d0033f6e1d3 192 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 89 189 2.9E-40 T 14-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 LH59_17925 815f820b30ffd219b1679d0033f6e1d3 192 PRINTS PR01703 Manganese superoxide dismutase signature 118 126 1.1E-22 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 LH59_17925 815f820b30ffd219b1679d0033f6e1d3 192 PRINTS PR01703 Manganese superoxide dismutase signature 155 167 1.1E-22 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 LH59_17925 815f820b30ffd219b1679d0033f6e1d3 192 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 1.1E-22 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 LH59_17925 815f820b30ffd219b1679d0033f6e1d3 192 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 1.1E-22 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 LH59_17925 815f820b30ffd219b1679d0033f6e1d3 192 PRINTS PR01703 Manganese superoxide dismutase signature 65 78 1.1E-22 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 LH59_17925 815f820b30ffd219b1679d0033f6e1d3 192 SUPERFAMILY SSF54719 85 191 2.62E-43 T 14-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 LH59_03810 f6109219cc45bf8571a44386481bcb55 152 Pfam PF02472 Biopolymer transport protein ExbD/TolR 12 138 1.6E-26 T 14-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 LH59_03810 f6109219cc45bf8571a44386481bcb55 152 Gene3D G3DSA:3.30.420.270 61 135 1.5E-10 T 14-10-2018 LH59_06750 0ba6255c7dae80e90f13f9eec3e72ed3 628 Gene3D G3DSA:3.40.50.300 319 624 2.1E-86 T 14-10-2018 LH59_06750 0ba6255c7dae80e90f13f9eec3e72ed3 628 Gene3D G3DSA:3.40.50.300 13 314 6.3E-82 T 14-10-2018 LH59_06750 0ba6255c7dae80e90f13f9eec3e72ed3 628 ProSitePatterns PS00211 ABC transporters family signature. 172 186 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_06750 0ba6255c7dae80e90f13f9eec3e72ed3 628 SUPERFAMILY SSF52540 321 571 3.19E-73 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_06750 0ba6255c7dae80e90f13f9eec3e72ed3 628 Pfam PF00005 ABC transporter 349 498 1.3E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_06750 0ba6255c7dae80e90f13f9eec3e72ed3 628 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 551 586 1.0E-8 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_06750 0ba6255c7dae80e90f13f9eec3e72ed3 628 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 251 283 1.3E-6 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_06750 0ba6255c7dae80e90f13f9eec3e72ed3 628 Pfam PF00005 ABC transporter 36 199 3.1E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_06750 0ba6255c7dae80e90f13f9eec3e72ed3 628 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 549 599 1.5E-10 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_06750 0ba6255c7dae80e90f13f9eec3e72ed3 628 SUPERFAMILY SSF52540 16 271 4.42E-64 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_06750 0ba6255c7dae80e90f13f9eec3e72ed3 628 SMART SM00382 357 549 3.4E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_06750 0ba6255c7dae80e90f13f9eec3e72ed3 628 SMART SM00382 44 249 1.2E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_06750 0ba6255c7dae80e90f13f9eec3e72ed3 628 ProSitePatterns PS00211 ABC transporters family signature. 472 486 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_11130 b6fde49d9f1487e0744a826b1cbc150a 304 SUPERFAMILY SSF53850 87 293 1.86E-27 T 14-10-2018 LH59_11130 b6fde49d9f1487e0744a826b1cbc150a 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 5.3E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_11130 b6fde49d9f1487e0744a826b1cbc150a 304 Gene3D G3DSA:3.40.190.10 91 276 1.7E-25 T 14-10-2018 LH59_11130 b6fde49d9f1487e0744a826b1cbc150a 304 Pfam PF03466 LysR substrate binding domain 87 290 8.9E-30 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_11130 b6fde49d9f1487e0744a826b1cbc150a 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.2E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_11130 b6fde49d9f1487e0744a826b1cbc150a 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.2E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_11130 b6fde49d9f1487e0744a826b1cbc150a 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.2E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_11130 b6fde49d9f1487e0744a826b1cbc150a 304 Gene3D G3DSA:1.10.10.10 1 85 1.6E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_11130 b6fde49d9f1487e0744a826b1cbc150a 304 Gene3D G3DSA:3.40.190.10 164 265 1.7E-25 T 14-10-2018 LH59_11130 b6fde49d9f1487e0744a826b1cbc150a 304 SUPERFAMILY SSF46785 3 79 2.27E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_06585 33e8a9a5c090a75ac3d3599cd1ee27b9 320 Gene3D G3DSA:3.40.190.150 24 310 4.9E-98 T 14-10-2018 LH59_06585 33e8a9a5c090a75ac3d3599cd1ee27b9 320 Gene3D G3DSA:3.40.190.10 122 245 4.9E-98 T 14-10-2018 LH59_06585 33e8a9a5c090a75ac3d3599cd1ee27b9 320 PIRSF PIRSF017082 1 320 1.6E-76 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_06585 33e8a9a5c090a75ac3d3599cd1ee27b9 320 SUPERFAMILY SSF53850 108 278 1.32E-11 T 14-10-2018 LH59_06585 33e8a9a5c090a75ac3d3599cd1ee27b9 320 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 44 316 5.6E-77 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_27880 730e76c0cf123655e2b490103f073b69 263 SUPERFAMILY SSF54821 108 206 1.11E-39 T 14-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27880 730e76c0cf123655e2b490103f073b69 263 Pfam PF07650 KH domain 39 110 2.7E-20 T 14-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27880 730e76c0cf123655e2b490103f073b69 263 ProSitePatterns PS00548 Ribosomal protein S3 signature. 163 197 - T 14-10-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27880 730e76c0cf123655e2b490103f073b69 263 Pfam PF00189 Ribosomal protein S3, C-terminal domain 120 202 5.2E-40 T 14-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27880 730e76c0cf123655e2b490103f073b69 263 SMART SM00322 60 125 2.7E-7 T 14-10-2018 IPR004087 K Homology domain GO:0003676 LH59_27880 730e76c0cf123655e2b490103f073b69 263 SUPERFAMILY SSF54814 2 106 1.54E-36 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 LH59_27880 730e76c0cf123655e2b490103f073b69 263 Gene3D G3DSA:3.30.300.20 17 107 2.9E-28 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta LH59_27880 730e76c0cf123655e2b490103f073b69 263 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 209 7.9E-92 T 14-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 LH59_27880 730e76c0cf123655e2b490103f073b69 263 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 38.491 T 14-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 LH59_27880 730e76c0cf123655e2b490103f073b69 263 Gene3D G3DSA:3.30.1140.32 108 208 2.5E-44 T 14-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_21450 e436750e2b41c76584293e4e077599d0 78 Gene3D G3DSA:2.30.170.40 2 77 5.7E-36 T 14-10-2018 IPR037147 Ribosomal protein L28/L24 superfamily GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_21450 e436750e2b41c76584293e4e077599d0 78 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 58 6.9E-31 T 14-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_21450 e436750e2b41c76584293e4e077599d0 78 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 67 23.245 T 14-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_21450 e436750e2b41c76584293e4e077599d0 78 SUPERFAMILY SSF143800 1 77 1.0E-33 T 14-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_21450 e436750e2b41c76584293e4e077599d0 78 Pfam PF00830 Ribosomal L28 family 3 62 9.5E-31 T 14-10-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_04670 1385a99cfe8ed417f29b04c410f291bd 385 Pfam PF01070 FMN-dependent dehydrogenase 18 381 1.4E-125 T 14-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 LH59_04670 1385a99cfe8ed417f29b04c410f291bd 385 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 278 284 - T 14-10-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 Reactome: R-HSA-9033241 LH59_04670 1385a99cfe8ed417f29b04c410f291bd 385 Gene3D G3DSA:3.20.20.70 6 385 1.6E-125 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_04670 1385a99cfe8ed417f29b04c410f291bd 385 SUPERFAMILY SSF51395 7 381 1.4E-91 T 14-10-2018 LH59_04670 1385a99cfe8ed417f29b04c410f291bd 385 PIRSF PIRSF000138 1 384 5.8E-121 T 14-10-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 Reactome: R-HSA-9033241 LH59_19535 e3a81256a7f6c13dc86e7e59be389517 378 Gene3D G3DSA:3.40.50.300 232 378 1.2E-23 T 14-10-2018 LH59_19535 e3a81256a7f6c13dc86e7e59be389517 378 Gene3D G3DSA:1.10.3210.10 32 186 1.5E-10 T 14-10-2018 LH59_19535 e3a81256a7f6c13dc86e7e59be389517 378 SUPERFAMILY SSF52540 238 371 2.32E-11 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_19535 e3a81256a7f6c13dc86e7e59be389517 378 SUPERFAMILY SSF109604 41 176 1.12E-15 T 14-10-2018 LH59_19535 e3a81256a7f6c13dc86e7e59be389517 378 Pfam PF01966 HD domain 48 140 5.0E-5 T 14-10-2018 IPR006674 HD domain LH59_19535 e3a81256a7f6c13dc86e7e59be389517 378 Pfam PF13671 AAA domain 239 362 1.5E-12 T 14-10-2018 LH59_09855 6056ee5c46fa3ba134f5a196078a7673 280 Gene3D G3DSA:1.10.10.10 3 84 1.2E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_09855 6056ee5c46fa3ba134f5a196078a7673 280 Pfam PF03466 LysR substrate binding domain 87 262 4.6E-29 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_09855 6056ee5c46fa3ba134f5a196078a7673 280 Gene3D G3DSA:3.40.190.10 160 253 1.6E-47 T 14-10-2018 LH59_09855 6056ee5c46fa3ba134f5a196078a7673 280 Gene3D G3DSA:3.40.190.10 94 258 1.6E-47 T 14-10-2018 LH59_09855 6056ee5c46fa3ba134f5a196078a7673 280 SUPERFAMILY SSF46785 2 110 2.98E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_09855 6056ee5c46fa3ba134f5a196078a7673 280 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 1.4E-16 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_09855 6056ee5c46fa3ba134f5a196078a7673 280 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 3.7E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_09855 6056ee5c46fa3ba134f5a196078a7673 280 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 3.7E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_09855 6056ee5c46fa3ba134f5a196078a7673 280 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 3.7E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_09855 6056ee5c46fa3ba134f5a196078a7673 280 SUPERFAMILY SSF53850 88 273 1.76E-28 T 14-10-2018 LH59_06705 ee17f2573ae9e006158731dd68963262 366 Gene3D G3DSA:1.10.630.10 3 352 7.4E-23 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 LH59_06705 ee17f2573ae9e006158731dd68963262 366 SUPERFAMILY SSF48264 9 333 8.12E-22 T 14-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 LH59_16270 a78549c03bd47e9bca30fe9d8e30e443 323 Gene3D G3DSA:3.40.190.10 124 247 1.4E-111 T 14-10-2018 LH59_16270 a78549c03bd47e9bca30fe9d8e30e443 323 PIRSF PIRSF017082 1 323 7.7E-83 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_16270 a78549c03bd47e9bca30fe9d8e30e443 323 SUPERFAMILY SSF53850 111 282 2.53E-12 T 14-10-2018 LH59_16270 a78549c03bd47e9bca30fe9d8e30e443 323 Gene3D G3DSA:3.40.190.150 26 313 1.4E-111 T 14-10-2018 LH59_16270 a78549c03bd47e9bca30fe9d8e30e443 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 318 4.5E-84 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_16645 9d0e0449bc0517b5906632366b3d627e 281 Pfam PF02811 PHP domain 9 101 3.3E-8 T 14-10-2018 IPR004013 PHP domain GO:0003824 LH59_16645 9d0e0449bc0517b5906632366b3d627e 281 SMART SM00481 8 73 7.2E-15 T 14-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal LH59_16645 9d0e0449bc0517b5906632366b3d627e 281 Gene3D G3DSA:3.20.20.140 8 254 6.3E-84 T 14-10-2018 LH59_16645 9d0e0449bc0517b5906632366b3d627e 281 Gene3D G3DSA:1.10.150.650 101 173 6.3E-84 T 14-10-2018 LH59_16645 9d0e0449bc0517b5906632366b3d627e 281 SUPERFAMILY SSF89550 6 280 5.89E-49 T 14-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 LH59_08725 81051f882633c796d8db1568d8724fb8 1163 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 296 736 8.2E-175 T 14-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LH59_08725 81051f882633c796d8db1568d8724fb8 1163 Pfam PF14579 Helix-hairpin-helix motif 809 907 6.0E-28 T 14-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LH59_08725 81051f882633c796d8db1568d8724fb8 1163 Pfam PF02811 PHP domain 13 177 2.5E-43 T 14-10-2018 IPR004013 PHP domain GO:0003824 LH59_08725 81051f882633c796d8db1568d8724fb8 1163 SUPERFAMILY SSF89550 11 267 4.9E-11 T 14-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 LH59_08725 81051f882633c796d8db1568d8724fb8 1163 SMART SM00481 12 79 6.7E-24 T 14-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal LH59_08725 81051f882633c796d8db1568d8724fb8 1163 Gene3D G3DSA:1.10.10.1600 438 517 5.2E-26 T 14-10-2018 LH59_08725 81051f882633c796d8db1568d8724fb8 1163 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 11 1033 0.0 T 14-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LH59_08725 81051f882633c796d8db1568d8724fb8 1163 Gene3D G3DSA:3.20.20.140 1 274 1.1E-85 T 14-10-2018 LH59_08725 81051f882633c796d8db1568d8724fb8 1163 Gene3D G3DSA:2.40.50.140 986 1077 3.2E-7 T 14-10-2018 LH59_08725 81051f882633c796d8db1568d8724fb8 1163 Pfam PF01336 OB-fold nucleic acid binding domain 999 1074 6.2E-11 T 14-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 LH59_17190 4c08238e09963bd00052b6a141a09cf2 403 Hamap MF_00331 Cysteine desulfurase IscS [iscS]. 2 394 55.684 T 14-10-2018 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 LH59_17190 4c08238e09963bd00052b6a141a09cf2 403 Gene3D G3DSA:3.90.1150.10 6 374 1.1E-164 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_17190 4c08238e09963bd00052b6a141a09cf2 403 Gene3D G3DSA:3.40.640.10 17 261 1.1E-164 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_17190 4c08238e09963bd00052b6a141a09cf2 403 PIRSF PIRSF005572 3 383 1.5E-135 T 14-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 LH59_17190 4c08238e09963bd00052b6a141a09cf2 403 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 196 215 - T 14-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site LH59_17190 4c08238e09963bd00052b6a141a09cf2 403 SUPERFAMILY SSF53383 5 390 6.72E-113 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_17190 4c08238e09963bd00052b6a141a09cf2 403 Pfam PF00266 Aminotransferase class-V 6 367 5.9E-90 T 14-10-2018 IPR000192 Aminotransferase class V domain LH59_17190 4c08238e09963bd00052b6a141a09cf2 403 TIGRFAM TIGR02006 IscS: cysteine desulfurase IscS 4 403 9.3E-229 T 14-10-2018 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 LH59_08170 0bc1ed9a32eeecadc72a44e1a9658ff7 499 Pfam PF02913 FAD linked oxidases, C-terminal domain 231 471 2.8E-66 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 LH59_08170 0bc1ed9a32eeecadc72a44e1a9658ff7 499 Gene3D G3DSA:3.30.70.2740 351 431 1.5E-7 T 14-10-2018 LH59_08170 0bc1ed9a32eeecadc72a44e1a9658ff7 499 SUPERFAMILY SSF56176 19 231 5.14E-69 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 LH59_08170 0bc1ed9a32eeecadc72a44e1a9658ff7 499 Gene3D G3DSA:3.30.465.40 20 250 8.2E-63 T 14-10-2018 LH59_08170 0bc1ed9a32eeecadc72a44e1a9658ff7 499 Pfam PF01565 FAD binding domain 56 195 3.3E-40 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 LH59_08170 0bc1ed9a32eeecadc72a44e1a9658ff7 499 Gene3D G3DSA:1.10.45.10 432 472 7.5E-6 T 14-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 LH59_08170 0bc1ed9a32eeecadc72a44e1a9658ff7 499 SUPERFAMILY SSF55103 205 474 4.58E-74 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 LH59_11015 ff53365627d83cbdd016670bee88e51f 472 Hamap MF_00006 Argininosuccinate lyase [argH]. 17 468 43.04 T 14-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 LH59_11015 ff53365627d83cbdd016670bee88e51f 472 TIGRFAM TIGR00838 argH: argininosuccinate lyase 19 462 1.6E-185 T 14-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 LH59_11015 ff53365627d83cbdd016670bee88e51f 472 Gene3D G3DSA:1.10.40.30 375 447 1.2E-189 T 14-10-2018 LH59_11015 ff53365627d83cbdd016670bee88e51f 472 PRINTS PR00149 Fumarate lyase superfamily signature 117 135 8.0E-29 T 14-10-2018 IPR000362 Fumarate lyase family LH59_11015 ff53365627d83cbdd016670bee88e51f 472 PRINTS PR00149 Fumarate lyase superfamily signature 162 180 8.0E-29 T 14-10-2018 IPR000362 Fumarate lyase family LH59_11015 ff53365627d83cbdd016670bee88e51f 472 PRINTS PR00149 Fumarate lyase superfamily signature 290 306 8.0E-29 T 14-10-2018 IPR000362 Fumarate lyase family LH59_11015 ff53365627d83cbdd016670bee88e51f 472 PRINTS PR00149 Fumarate lyase superfamily signature 246 273 8.0E-29 T 14-10-2018 IPR000362 Fumarate lyase family LH59_11015 ff53365627d83cbdd016670bee88e51f 472 Gene3D G3DSA:1.10.275.10 40 244 1.2E-189 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal LH59_11015 ff53365627d83cbdd016670bee88e51f 472 Pfam PF14698 Argininosuccinate lyase C-terminal 378 446 1.3E-27 T 14-10-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 LH59_11015 ff53365627d83cbdd016670bee88e51f 472 Pfam PF00206 Lyase 22 315 4.5E-73 T 14-10-2018 IPR022761 Fumarate lyase, N-terminal LH59_11015 ff53365627d83cbdd016670bee88e51f 472 SUPERFAMILY SSF48557 19 463 6.6E-149 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 LH59_11015 ff53365627d83cbdd016670bee88e51f 472 Gene3D G3DSA:1.20.200.10 134 461 1.2E-189 T 14-10-2018 LH59_11015 ff53365627d83cbdd016670bee88e51f 472 PRINTS PR00145 Argininosuccinate lyase family signature 246 270 1.8E-66 T 14-10-2018 LH59_11015 ff53365627d83cbdd016670bee88e51f 472 PRINTS PR00145 Argininosuccinate lyase family signature 290 306 1.8E-66 T 14-10-2018 LH59_11015 ff53365627d83cbdd016670bee88e51f 472 PRINTS PR00145 Argininosuccinate lyase family signature 157 177 1.8E-66 T 14-10-2018 LH59_11015 ff53365627d83cbdd016670bee88e51f 472 PRINTS PR00145 Argininosuccinate lyase family signature 325 344 1.8E-66 T 14-10-2018 LH59_11015 ff53365627d83cbdd016670bee88e51f 472 PRINTS PR00145 Argininosuccinate lyase family signature 116 138 1.8E-66 T 14-10-2018 LH59_11015 ff53365627d83cbdd016670bee88e51f 472 PRINTS PR00145 Argininosuccinate lyase family signature 208 224 1.8E-66 T 14-10-2018 LH59_11015 ff53365627d83cbdd016670bee88e51f 472 ProSitePatterns PS00163 Fumarate lyases signature. 290 299 - T 14-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 LH59_12655 b01fddd210cb20bc14e41b743a847b06 238 Gene3D G3DSA:1.10.760.10 129 219 6.9E-25 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_12655 b01fddd210cb20bc14e41b743a847b06 238 Gene3D G3DSA:1.10.760.10 30 112 1.7E-21 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_12655 b01fddd210cb20bc14e41b743a847b06 238 PRINTS PR00605 Class IC cytochrome C signature 44 55 7.4E-5 T 14-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 LH59_12655 b01fddd210cb20bc14e41b743a847b06 238 PRINTS PR00605 Class IC cytochrome C signature 194 216 7.4E-5 T 14-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 LH59_12655 b01fddd210cb20bc14e41b743a847b06 238 SUPERFAMILY SSF46626 133 218 9.31E-21 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_12655 b01fddd210cb20bc14e41b743a847b06 238 PIRSF PIRSF000005 4 221 1.9E-60 T 14-10-2018 IPR024167 Cytochrome c4-like GO:0005506|GO:0009055|GO:0020037|GO:0042597 LH59_12655 b01fddd210cb20bc14e41b743a847b06 238 SUPERFAMILY SSF46626 44 115 4.34E-19 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_12655 b01fddd210cb20bc14e41b743a847b06 238 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 150 215 1.2E-7 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_12655 b01fddd210cb20bc14e41b743a847b06 238 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 45 108 4.3E-6 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_07105 d41d4b3becfa0ea06acafca526d4a898 290 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 4 283 1.2E-52 T 14-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 LH59_07105 d41d4b3becfa0ea06acafca526d4a898 290 Gene3D G3DSA:3.10.310.10 115 277 3.3E-68 T 14-10-2018 LH59_07105 d41d4b3becfa0ea06acafca526d4a898 290 Gene3D G3DSA:3.10.310.10 9 279 3.3E-68 T 14-10-2018 LH59_07105 d41d4b3becfa0ea06acafca526d4a898 290 PIRSF PIRSF016184 1 290 1.1E-64 T 14-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 LH59_07105 d41d4b3becfa0ea06acafca526d4a898 290 SUPERFAMILY SSF54506 3 288 1.48E-66 T 14-10-2018 LH59_07105 d41d4b3becfa0ea06acafca526d4a898 290 Pfam PF02567 Phenazine biosynthesis-like protein 10 281 6.5E-49 T 14-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 LH59_10745 1c3016960e6b256ee21a526641218487 636 SUPERFAMILY SSF90123 21 328 9.81E-46 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 LH59_10745 1c3016960e6b256ee21a526641218487 636 SMART SM00382 380 566 5.6E-19 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_10745 1c3016960e6b256ee21a526641218487 636 Pfam PF00664 ABC transporter transmembrane region 32 307 8.0E-18 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 LH59_10745 1c3016960e6b256ee21a526641218487 636 Pfam PF00005 ABC transporter 372 520 3.1E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_10745 1c3016960e6b256ee21a526641218487 636 ProSitePatterns PS00211 ABC transporters family signature. 492 506 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_10745 1c3016960e6b256ee21a526641218487 636 SUPERFAMILY SSF52540 348 591 1.05E-87 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_10745 1c3016960e6b256ee21a526641218487 636 Gene3D G3DSA:3.40.50.300 344 603 8.1E-91 T 14-10-2018 LH59_10745 1c3016960e6b256ee21a526641218487 636 Gene3D G3DSA:1.20.1560.10 4 341 7.7E-50 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 LH59_04260 216bd278b82d43cd0721416edb9e16eb 287 PIRSF PIRSF017388 2 150 2.4E-22 T 14-10-2018 IPR012354 Esterase/lipase GO:0052689 LH59_04260 216bd278b82d43cd0721416edb9e16eb 287 PIRSF PIRSF017388 159 255 1.9E-14 T 14-10-2018 IPR012354 Esterase/lipase GO:0052689 LH59_04260 216bd278b82d43cd0721416edb9e16eb 287 Pfam PF12697 Alpha/beta hydrolase family 9 241 5.2E-13 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_04260 216bd278b82d43cd0721416edb9e16eb 287 SUPERFAMILY SSF53474 8 252 1.19E-30 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_04260 216bd278b82d43cd0721416edb9e16eb 287 Gene3D G3DSA:3.40.50.1820 1 253 6.6E-44 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_27540 8851e404e2fdd598cd74e071ee784b4c 161 SMART SM00065 29 161 0.0019 T 14-10-2018 IPR003018 GAF domain GO:0005515 LH59_27540 8851e404e2fdd598cd74e071ee784b4c 161 SUPERFAMILY SSF55781 11 158 1.22E-43 T 14-10-2018 LH59_27540 8851e404e2fdd598cd74e071ee784b4c 161 ProSitePatterns PS01320 Uncharacterized protein family UPF0067 signature. 99 116 - T 14-10-2018 IPR000614 Free Met sulfoxide reductase conserved site LH59_27540 8851e404e2fdd598cd74e071ee784b4c 161 Pfam PF13185 GAF domain 54 153 2.9E-10 T 14-10-2018 IPR003018 GAF domain GO:0005515 LH59_27540 8851e404e2fdd598cd74e071ee784b4c 161 Gene3D G3DSA:3.30.450.40 11 160 2.9E-65 T 14-10-2018 IPR029016 GAF-like domain superfamily LH59_21885 f9b946072d2224dad1661cc288a894ad 338 SUPERFAMILY SSF161098 46 323 1.13E-33 T 14-10-2018 IPR035906 MetI-like superfamily LH59_21885 f9b946072d2224dad1661cc288a894ad 338 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 327 4.3E-14 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_21885 f9b946072d2224dad1661cc288a894ad 338 Gene3D G3DSA:1.10.3720.10 91 334 1.8E-29 T 14-10-2018 IPR035906 MetI-like superfamily LH59_21885 f9b946072d2224dad1661cc288a894ad 338 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 37 329 9.8E-91 T 14-10-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 LH59_14700 ecbeaf1eab00f2ce90fb956b650bf546 165 Pfam PF01641 SelR domain 45 163 8.6E-51 T 14-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 LH59_14700 ecbeaf1eab00f2ce90fb956b650bf546 165 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 41 164 3.9E-52 T 14-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 LH59_14700 ecbeaf1eab00f2ce90fb956b650bf546 165 Gene3D G3DSA:2.170.150.20 28 165 1.7E-57 T 14-10-2018 LH59_14700 ecbeaf1eab00f2ce90fb956b650bf546 165 SUPERFAMILY SSF51316 41 164 1.36E-56 T 14-10-2018 IPR011057 Mss4-like superfamily LH59_11840 a43ea9f041eea45592dd4abad06000e1 247 SMART SM00079 28 244 2.0E-6 T 14-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 LH59_11840 a43ea9f041eea45592dd4abad06000e1 247 Gene3D G3DSA:3.40.190.10 33 242 4.4E-70 T 14-10-2018 LH59_11840 a43ea9f041eea45592dd4abad06000e1 247 Gene3D G3DSA:3.40.190.10 112 204 4.4E-70 T 14-10-2018 LH59_11840 a43ea9f041eea45592dd4abad06000e1 247 SMART SM00062 28 245 1.0E-70 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_11840 a43ea9f041eea45592dd4abad06000e1 247 SUPERFAMILY SSF53850 9 243 1.37E-71 T 14-10-2018 LH59_11840 a43ea9f041eea45592dd4abad06000e1 247 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 29 243 1.7E-63 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_11840 a43ea9f041eea45592dd4abad06000e1 247 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 50 63 - T 14-10-2018 IPR018313 Solute-binding protein family 3, conserved site LH59_19730 de9eff3ca40466583e777a07babfc752 234 Gene3D G3DSA:2.40.30.10 7 109 2.8E-21 T 14-10-2018 LH59_19730 de9eff3ca40466583e777a07babfc752 234 Gene3D G3DSA:3.40.50.80 115 234 1.0E-14 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain LH59_19730 de9eff3ca40466583e777a07babfc752 234 Pfam PF08021 Siderophore-interacting FAD-binding domain 60 108 6.8E-14 T 14-10-2018 IPR013113 FAD-binding 9, siderophore-interacting LH59_19730 de9eff3ca40466583e777a07babfc752 234 Pfam PF04954 Siderophore-interacting protein 119 228 1.7E-11 T 14-10-2018 IPR007037 Siderophore-interacting protein, C-terminal domain LH59_19730 de9eff3ca40466583e777a07babfc752 234 SUPERFAMILY SSF63380 4 110 2.69E-11 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel LH59_01770 f331bc7183533891038baccee3490e9b 353 SUPERFAMILY SSF55326 12 167 1.29E-40 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily LH59_01770 f331bc7183533891038baccee3490e9b 353 Hamap MF_00625 Selenide, water dikinase [selD]. 10 353 44.457 T 14-10-2018 IPR023061 Selenophosphate synthetase, class I GO:0004756|GO:0005524|GO:0016260 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 LH59_01770 f331bc7183533891038baccee3490e9b 353 Gene3D G3DSA:3.30.1330.10 4 167 9.6E-49 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily LH59_01770 f331bc7183533891038baccee3490e9b 353 Pfam PF02769 AIR synthase related protein, C-terminal domain 174 349 1.0E-28 T 14-10-2018 IPR010918 PurM-like, C-terminal domain LH59_01770 f331bc7183533891038baccee3490e9b 353 Gene3D G3DSA:3.90.650.10 169 352 2.7E-50 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily LH59_01770 f331bc7183533891038baccee3490e9b 353 Pfam PF00586 AIR synthase related protein, N-terminal domain 55 162 6.8E-20 T 14-10-2018 IPR016188 PurM-like, N-terminal domain LH59_01770 f331bc7183533891038baccee3490e9b 353 PIRSF PIRSF036407 6 352 3.0E-116 T 14-10-2018 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 LH59_01770 f331bc7183533891038baccee3490e9b 353 SUPERFAMILY SSF56042 169 349 1.64E-46 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily LH59_01770 f331bc7183533891038baccee3490e9b 353 TIGRFAM TIGR00476 selD: selenide, water dikinase 12 321 2.6E-132 T 14-10-2018 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 LH59_18415 1298fff664aa598433668f11b820b1f0 276 SUPERFAMILY SSF161098 72 259 3.79E-23 T 14-10-2018 IPR035906 MetI-like superfamily LH59_18415 1298fff664aa598433668f11b820b1f0 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 272 2.7E-27 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_18415 1298fff664aa598433668f11b820b1f0 276 Gene3D G3DSA:1.10.3720.10 64 272 1.5E-17 T 14-10-2018 IPR035906 MetI-like superfamily LH59_14780 a3fdfc52e112a2a0168c0bb9293bc1f7 181 Gene3D G3DSA:3.30.1130.10 51 181 9.1E-61 T 14-10-2018 LH59_14780 a3fdfc52e112a2a0168c0bb9293bc1f7 181 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 108 118 - T 14-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 LH59_14780 a3fdfc52e112a2a0168c0bb9293bc1f7 181 SUPERFAMILY SSF55620 3 181 3.26E-78 T 14-10-2018 LH59_14780 a3fdfc52e112a2a0168c0bb9293bc1f7 181 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 60 76 - T 14-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 LH59_14780 a3fdfc52e112a2a0168c0bb9293bc1f7 181 Pfam PF01227 GTP cyclohydrolase I 4 180 2.0E-75 T 14-10-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 LH59_14780 a3fdfc52e112a2a0168c0bb9293bc1f7 181 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 1 181 37.027 T 14-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 LH59_14780 a3fdfc52e112a2a0168c0bb9293bc1f7 181 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 4 181 8.0E-75 T 14-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 LH59_14780 a3fdfc52e112a2a0168c0bb9293bc1f7 181 Gene3D G3DSA:1.10.286.10 1 50 3.5E-20 T 14-10-2018 LH59_22260 4958aceb5e76ec8076a6d649e8093a35 386 SUPERFAMILY SSF53822 27 379 1.47E-85 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_22260 4958aceb5e76ec8076a6d649e8093a35 386 Pfam PF13458 Periplasmic binding protein 27 364 1.6E-71 T 14-10-2018 IPR028081 Leucine-binding protein domain LH59_22260 4958aceb5e76ec8076a6d649e8093a35 386 Gene3D G3DSA:3.40.50.2300 144 361 1.7E-110 T 14-10-2018 LH59_22260 4958aceb5e76ec8076a6d649e8093a35 386 Gene3D G3DSA:3.40.50.2300 28 355 1.7E-110 T 14-10-2018 LH59_12475 040fc811e6b7cb28a91f5d50d162747b 231 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 17 192 2.3E-29 T 14-10-2018 LH59_12475 040fc811e6b7cb28a91f5d50d162747b 231 Gene3D G3DSA:3.40.50.1000 5 227 2.5E-71 T 14-10-2018 IPR023214 HAD superfamily LH59_12475 040fc811e6b7cb28a91f5d50d162747b 231 Pfam PF12710 haloacid dehalogenase-like hydrolase 18 192 1.2E-23 T 14-10-2018 LH59_12475 040fc811e6b7cb28a91f5d50d162747b 231 SUPERFAMILY SSF56784 14 227 2.76E-45 T 14-10-2018 IPR036412 HAD-like superfamily LH59_12475 040fc811e6b7cb28a91f5d50d162747b 231 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 14 225 1.0E-57 T 14-10-2018 LH59_02410 63439552bb61d9675e4dc913f97055a1 256 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 3 247 47.037 T 14-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 LH59_02410 63439552bb61d9675e4dc913f97055a1 256 Pfam PF03746 LamB/YcsF family 5 243 1.7E-103 T 14-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 LH59_02410 63439552bb61d9675e4dc913f97055a1 256 SUPERFAMILY SSF88713 4 250 2.59E-100 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 LH59_02410 63439552bb61d9675e4dc913f97055a1 256 Gene3D G3DSA:3.20.20.370 3 254 1.3E-106 T 14-10-2018 LH59_09525 3d596d353721c56c8428c6a9a0070c7e 341 Pfam PF00356 Bacterial regulatory proteins, lacI family 15 60 9.1E-17 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 LH59_09525 3d596d353721c56c8428c6a9a0070c7e 341 Gene3D G3DSA:3.40.50.2300 170 302 1.3E-70 T 14-10-2018 LH59_09525 3d596d353721c56c8428c6a9a0070c7e 341 Gene3D G3DSA:1.10.260.40 6 71 3.0E-21 T 14-10-2018 LH59_09525 3d596d353721c56c8428c6a9a0070c7e 341 ProSitePatterns PS00356 LacI-type HTH domain signature. 16 34 - T 14-10-2018 LH59_09525 3d596d353721c56c8428c6a9a0070c7e 341 SUPERFAMILY SSF47413 13 71 5.06E-16 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 LH59_09525 3d596d353721c56c8428c6a9a0070c7e 341 Gene3D G3DSA:3.40.50.2300 76 322 1.3E-70 T 14-10-2018 LH59_09525 3d596d353721c56c8428c6a9a0070c7e 341 SMART SM00354 13 83 2.4E-23 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 LH59_09525 3d596d353721c56c8428c6a9a0070c7e 341 SUPERFAMILY SSF53822 70 329 5.07E-58 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_09525 3d596d353721c56c8428c6a9a0070c7e 341 Pfam PF13377 Periplasmic binding protein-like domain 181 341 3.6E-31 T 14-10-2018 LH59_02275 f5abbd026db535d8b017e72a90235ed3 251 Gene3D G3DSA:3.40.50.300 1 249 7.7E-56 T 14-10-2018 LH59_02275 f5abbd026db535d8b017e72a90235ed3 251 Pfam PF00005 ABC transporter 21 176 7.1E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_02275 f5abbd026db535d8b017e72a90235ed3 251 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 223 245 1.2E-8 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal LH59_02275 f5abbd026db535d8b017e72a90235ed3 251 SMART SM00382 29 222 7.3E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_02275 f5abbd026db535d8b017e72a90235ed3 251 SUPERFAMILY SSF52540 3 246 3.88E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_04000 7f04bad1e18003623175cbe4c693ffa5 611 Pfam PF00005 ABC transporter 303 436 5.9E-23 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_04000 7f04bad1e18003623175cbe4c693ffa5 611 SUPERFAMILY SSF52540 281 481 3.31E-47 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_04000 7f04bad1e18003623175cbe4c693ffa5 611 Pfam PF16326 ABC transporter C-terminal domain 536 604 1.2E-15 T 14-10-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 LH59_04000 7f04bad1e18003623175cbe4c693ffa5 611 ProSitePatterns PS00211 ABC transporters family signature. 408 422 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_04000 7f04bad1e18003623175cbe4c693ffa5 611 Pfam PF12848 ABC transporter 191 266 4.0E-10 T 14-10-2018 IPR032781 ABC-transporter extension domain LH59_04000 7f04bad1e18003623175cbe4c693ffa5 611 Pfam PF00005 ABC transporter 22 152 1.8E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_04000 7f04bad1e18003623175cbe4c693ffa5 611 Gene3D G3DSA:3.40.50.300 248 517 1.3E-63 T 14-10-2018 LH59_04000 7f04bad1e18003623175cbe4c693ffa5 611 Gene3D G3DSA:3.40.50.300 2 229 6.5E-62 T 14-10-2018 LH59_04000 7f04bad1e18003623175cbe4c693ffa5 611 SMART SM00382 31 197 5.4E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_04000 7f04bad1e18003623175cbe4c693ffa5 611 SMART SM00382 311 482 2.6E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_04000 7f04bad1e18003623175cbe4c693ffa5 611 SUPERFAMILY SSF52540 6 200 3.83E-49 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_04000 7f04bad1e18003623175cbe4c693ffa5 611 Gene3D G3DSA:1.10.287.380 525 610 5.0E-19 T 14-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 LH59_00175 bc0e83435fa63f14ea0850ffe6aefacc 265 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 55 69 2.6E-9 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_00175 bc0e83435fa63f14ea0850ffe6aefacc 265 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 69 85 2.6E-9 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_00175 bc0e83435fa63f14ea0850ffe6aefacc 265 Pfam PF00392 Bacterial regulatory proteins, gntR family 33 95 9.7E-21 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_00175 bc0e83435fa63f14ea0850ffe6aefacc 265 Gene3D G3DSA:1.10.10.10 16 95 2.3E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_00175 bc0e83435fa63f14ea0850ffe6aefacc 265 Gene3D G3DSA:3.40.1410.10 115 264 1.8E-21 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily LH59_00175 bc0e83435fa63f14ea0850ffe6aefacc 265 SMART SM00866 116 257 6.1E-12 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LH59_00175 bc0e83435fa63f14ea0850ffe6aefacc 265 SUPERFAMILY SSF46785 29 99 1.57E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_00175 bc0e83435fa63f14ea0850ffe6aefacc 265 Pfam PF07702 UTRA domain 127 257 6.9E-14 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LH59_00175 bc0e83435fa63f14ea0850ffe6aefacc 265 SUPERFAMILY SSF64288 83 263 3.77E-26 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily LH59_00175 bc0e83435fa63f14ea0850ffe6aefacc 265 SMART SM00345 36 95 4.2E-18 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_11945 22dd944b21ec3abe64fd992acdf961c3 472 PRINTS PR00147 DNA photolyase signature 326 342 6.5E-25 T 14-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 LH59_11945 22dd944b21ec3abe64fd992acdf961c3 472 PRINTS PR00147 DNA photolyase signature 385 399 6.5E-25 T 14-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 LH59_11945 22dd944b21ec3abe64fd992acdf961c3 472 PRINTS PR00147 DNA photolyase signature 142 158 6.5E-25 T 14-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 LH59_11945 22dd944b21ec3abe64fd992acdf961c3 472 PRINTS PR00147 DNA photolyase signature 346 364 6.5E-25 T 14-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 LH59_11945 22dd944b21ec3abe64fd992acdf961c3 472 Gene3D G3DSA:1.10.579.10 294 471 9.5E-73 T 14-10-2018 LH59_11945 22dd944b21ec3abe64fd992acdf961c3 472 ProSitePatterns PS00394 DNA photolyases class 1 signature 1. 326 338 - T 14-10-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal LH59_11945 22dd944b21ec3abe64fd992acdf961c3 472 Gene3D G3DSA:1.25.40.80 133 287 8.4E-78 T 14-10-2018 LH59_11945 22dd944b21ec3abe64fd992acdf961c3 472 Pfam PF00875 DNA photolyase 4 167 3.7E-45 T 14-10-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-400253 LH59_11945 22dd944b21ec3abe64fd992acdf961c3 472 Gene3D G3DSA:3.40.50.620 4 203 8.4E-78 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LH59_11945 22dd944b21ec3abe64fd992acdf961c3 472 SUPERFAMILY SSF52425 2 185 6.8E-52 T 14-10-2018 IPR036155 Cryptochrome/photolyase, N-terminal domain superfamily Reactome: R-HSA-400253 LH59_11945 22dd944b21ec3abe64fd992acdf961c3 472 SUPERFAMILY SSF48173 196 467 1.13E-101 T 14-10-2018 IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily Reactome: R-HSA-400253 LH59_11945 22dd944b21ec3abe64fd992acdf961c3 472 Pfam PF03441 FAD binding domain of DNA photolyase 276 466 8.9E-78 T 14-10-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-400253 LH59_11005 dc37d3167fafffa71e3553172630d3ad 467 Gene3D G3DSA:3.50.50.60 154 273 4.8E-109 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_11005 dc37d3167fafffa71e3553172630d3ad 467 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 10 329 4.9E-68 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LH59_11005 dc37d3167fafffa71e3553172630d3ad 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 145 154 2.9E-68 T 14-10-2018 LH59_11005 dc37d3167fafffa71e3553172630d3ad 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 309 316 2.9E-68 T 14-10-2018 LH59_11005 dc37d3167fafffa71e3553172630d3ad 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 267 281 2.9E-68 T 14-10-2018 LH59_11005 dc37d3167fafffa71e3553172630d3ad 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 180 205 2.9E-68 T 14-10-2018 LH59_11005 dc37d3167fafffa71e3553172630d3ad 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 431 451 2.9E-68 T 14-10-2018 LH59_11005 dc37d3167fafffa71e3553172630d3ad 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 41 56 2.9E-68 T 14-10-2018 LH59_11005 dc37d3167fafffa71e3553172630d3ad 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 9 31 2.9E-68 T 14-10-2018 LH59_11005 dc37d3167fafffa71e3553172630d3ad 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 344 365 2.9E-68 T 14-10-2018 LH59_11005 dc37d3167fafffa71e3553172630d3ad 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 409 424 2.9E-68 T 14-10-2018 LH59_11005 dc37d3167fafffa71e3553172630d3ad 467 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 10 467 6.0E-145 T 14-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 LH59_11005 dc37d3167fafffa71e3553172630d3ad 467 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 42 52 - T 14-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 LH59_11005 dc37d3167fafffa71e3553172630d3ad 467 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 348 457 2.5E-29 T 14-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 LH59_11005 dc37d3167fafffa71e3553172630d3ad 467 Gene3D G3DSA:3.30.390.30 347 467 1.6E-38 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 LH59_11005 dc37d3167fafffa71e3553172630d3ad 467 Gene3D G3DSA:3.50.50.60 10 334 4.8E-109 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_11005 dc37d3167fafffa71e3553172630d3ad 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 142 160 2.5E-37 T 14-10-2018 LH59_11005 dc37d3167fafffa71e3553172630d3ad 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 2.5E-37 T 14-10-2018 LH59_11005 dc37d3167fafffa71e3553172630d3ad 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 180 198 2.5E-37 T 14-10-2018 LH59_11005 dc37d3167fafffa71e3553172630d3ad 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 294 316 2.5E-37 T 14-10-2018 LH59_11005 dc37d3167fafffa71e3553172630d3ad 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 282 2.5E-37 T 14-10-2018 LH59_11005 dc37d3167fafffa71e3553172630d3ad 467 PIRSF PIRSF000350 1 461 2.3E-76 T 14-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 LH59_11005 dc37d3167fafffa71e3553172630d3ad 467 SUPERFAMILY SSF51905 3 339 5.49E-57 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_11005 dc37d3167fafffa71e3553172630d3ad 467 SUPERFAMILY SSF55424 347 466 1.49E-32 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 LH59_01245 0d03942fa6eeb38eb07cc5e69786efee 285 Pfam PF12833 Helix-turn-helix domain 205 284 8.1E-23 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_01245 0d03942fa6eeb38eb07cc5e69786efee 285 Gene3D G3DSA:1.10.10.60 184 285 6.2E-28 T 14-10-2018 LH59_01245 0d03942fa6eeb38eb07cc5e69786efee 285 SUPERFAMILY SSF46689 182 233 1.25E-8 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_01245 0d03942fa6eeb38eb07cc5e69786efee 285 SUPERFAMILY SSF46689 236 284 3.45E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_01245 0d03942fa6eeb38eb07cc5e69786efee 285 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 236 278 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 LH59_01245 0d03942fa6eeb38eb07cc5e69786efee 285 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 251 266 1.3E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 LH59_01245 0d03942fa6eeb38eb07cc5e69786efee 285 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 266 282 1.3E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 LH59_01245 0d03942fa6eeb38eb07cc5e69786efee 285 SMART SM00342 199 282 8.1E-28 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_09375 3a9078d9326cc183cf3dce89010b72db 660 SUPERFAMILY SSF141868 425 655 5.89E-25 T 14-10-2018 IPR035919 EAL domain superfamily LH59_09375 3a9078d9326cc183cf3dce89010b72db 660 Gene3D G3DSA:3.20.20.450 417 656 2.8E-29 T 14-10-2018 IPR035919 EAL domain superfamily LH59_09375 3a9078d9326cc183cf3dce89010b72db 660 SMART SM00052 419 652 1.1E-6 T 14-10-2018 IPR001633 EAL domain LH59_09375 3a9078d9326cc183cf3dce89010b72db 660 Gene3D G3DSA:3.30.1040.50 101 151 6.5E-14 T 14-10-2018 LH59_09375 3a9078d9326cc183cf3dce89010b72db 660 Pfam PF00990 Diguanylate cyclase, GGDEF domain 237 364 7.5E-10 T 14-10-2018 IPR000160 GGDEF domain LH59_09375 3a9078d9326cc183cf3dce89010b72db 660 Pfam PF16448 LapD/MoxY periplasmic domain 24 145 3.3E-39 T 14-10-2018 IPR032244 LapD/MoxY, periplasmic domain LH59_09375 3a9078d9326cc183cf3dce89010b72db 660 Pfam PF00563 EAL domain 426 648 3.3E-22 T 14-10-2018 IPR001633 EAL domain LH59_09375 3a9078d9326cc183cf3dce89010b72db 660 SMART SM00267 225 407 4.2E-7 T 14-10-2018 IPR000160 GGDEF domain LH59_09375 3a9078d9326cc183cf3dce89010b72db 660 SUPERFAMILY SSF55073 242 406 1.18E-11 T 14-10-2018 IPR029787 Nucleotide cyclase LH59_09375 3a9078d9326cc183cf3dce89010b72db 660 Gene3D G3DSA:3.30.70.270 220 407 3.9E-20 T 14-10-2018 LH59_22895 8aab605d5b85dea75b38801e73bf13bb 401 Gene3D G3DSA:3.90.105.10 21 168 1.2E-124 T 14-10-2018 LH59_22895 8aab605d5b85dea75b38801e73bf13bb 401 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 171 308 3.3E-27 T 14-10-2018 IPR001453 MoaB/Mog domain LH59_22895 8aab605d5b85dea75b38801e73bf13bb 401 Gene3D G3DSA:2.40.340.10 322 384 1.2E-124 T 14-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 LH59_22895 8aab605d5b85dea75b38801e73bf13bb 401 SMART SM00852 174 312 3.3E-42 T 14-10-2018 IPR001453 MoaB/Mog domain LH59_22895 8aab605d5b85dea75b38801e73bf13bb 401 Pfam PF03453 MoeA N-terminal region (domain I and II) 4 161 2.9E-41 T 14-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 LH59_22895 8aab605d5b85dea75b38801e73bf13bb 401 SUPERFAMILY SSF53218 171 316 2.49E-41 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily LH59_22895 8aab605d5b85dea75b38801e73bf13bb 401 Gene3D G3DSA:2.170.190.11 45 135 1.2E-124 T 14-10-2018 LH59_22895 8aab605d5b85dea75b38801e73bf13bb 401 Pfam PF03454 MoeA C-terminal region (domain IV) 327 384 7.9E-10 T 14-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 LH59_22895 8aab605d5b85dea75b38801e73bf13bb 401 SUPERFAMILY SSF63882 1 170 3.66E-51 T 14-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 LH59_22895 8aab605d5b85dea75b38801e73bf13bb 401 Gene3D G3DSA:3.40.980.10 169 321 1.2E-124 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily LH59_22895 8aab605d5b85dea75b38801e73bf13bb 401 SUPERFAMILY SSF63867 321 394 1.96E-11 T 14-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 LH59_22895 8aab605d5b85dea75b38801e73bf13bb 401 ProSitePatterns PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 247 281 - T 14-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 LH59_22895 8aab605d5b85dea75b38801e73bf13bb 401 Pfam PF00994 Probable molybdopterin binding domain 174 311 6.3E-28 T 14-10-2018 IPR001453 MoaB/Mog domain LH59_09675 1992ed2c46066a88ef5dcfcc9ccb5a7f 119 Gene3D G3DSA:1.10.720.90 2 55 4.6E-25 T 14-10-2018 LH59_09675 1992ed2c46066a88ef5dcfcc9ccb5a7f 119 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 6.3E-49 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_09675 1992ed2c46066a88ef5dcfcc9ccb5a7f 119 Pfam PF00453 Ribosomal protein L20 3 109 1.3E-48 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_09675 1992ed2c46066a88ef5dcfcc9ccb5a7f 119 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 30.158 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_09675 1992ed2c46066a88ef5dcfcc9ccb5a7f 119 SUPERFAMILY SSF74731 2 117 2.62E-49 T 14-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_09675 1992ed2c46066a88ef5dcfcc9ccb5a7f 119 Gene3D G3DSA:1.10.1900.20 56 119 2.9E-29 T 14-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_09675 1992ed2c46066a88ef5dcfcc9ccb5a7f 119 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_09675 1992ed2c46066a88ef5dcfcc9ccb5a7f 119 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 71 4.0E-22 T 14-10-2018 LH59_09675 1992ed2c46066a88ef5dcfcc9ccb5a7f 119 PRINTS PR00062 Ribosomal protein L20 signature 12 41 1.7E-39 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_09675 1992ed2c46066a88ef5dcfcc9ccb5a7f 119 PRINTS PR00062 Ribosomal protein L20 signature 42 71 1.7E-39 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_09675 1992ed2c46066a88ef5dcfcc9ccb5a7f 119 PRINTS PR00062 Ribosomal protein L20 signature 75 101 1.7E-39 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_17245 91ac3faa669ef43be0df2adc61198ebd 181 TIGRFAM TIGR00645 HI0507: TIGR00645 family protein 12 179 2.0E-57 T 14-10-2018 IPR020761 Uncharacterised protein family UPF0114, bacteria LH59_17245 91ac3faa669ef43be0df2adc61198ebd 181 Pfam PF03350 Uncharacterized protein family, UPF0114 16 132 1.8E-40 T 14-10-2018 IPR005134 Uncharacterised protein family UPF0114 LH59_17245 91ac3faa669ef43be0df2adc61198ebd 181 Hamap MF_00143 UPF0114 protein YqhA [yqhA]. 1 181 90.739 T 14-10-2018 IPR020761 Uncharacterised protein family UPF0114, bacteria LH59_23185 c8403e26cfb8f2dab86d812b882d7543 348 Gene3D G3DSA:3.40.1570.10 18 284 3.6E-130 T 14-10-2018 LH59_23185 c8403e26cfb8f2dab86d812b882d7543 348 Pfam PF05171 Haemin-degrading HemS.ChuX domain 37 161 1.2E-37 T 14-10-2018 IPR007845 Haemin-degrading HemS/ChuX domain GO:0006826 LH59_23185 c8403e26cfb8f2dab86d812b882d7543 348 Pfam PF05171 Haemin-degrading HemS.ChuX domain 209 340 3.8E-43 T 14-10-2018 IPR007845 Haemin-degrading HemS/ChuX domain GO:0006826 LH59_23185 c8403e26cfb8f2dab86d812b882d7543 348 SUPERFAMILY SSF144064 13 342 5.49E-123 T 14-10-2018 LH59_23185 c8403e26cfb8f2dab86d812b882d7543 348 Gene3D G3DSA:3.40.1570.10 91 337 3.6E-130 T 14-10-2018 LH59_05025 c6bcefd0622b0a893413a2b24a4e2203 182 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 83 99 6.0E-32 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 LH59_05025 c6bcefd0622b0a893413a2b24a4e2203 182 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 4 17 6.0E-32 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 LH59_05025 c6bcefd0622b0a893413a2b24a4e2203 182 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 138 150 6.0E-32 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 LH59_05025 c6bcefd0622b0a893413a2b24a4e2203 182 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 61 77 6.0E-32 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 LH59_05025 c6bcefd0622b0a893413a2b24a4e2203 182 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 107 126 6.0E-32 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 LH59_05025 c6bcefd0622b0a893413a2b24a4e2203 182 Gene3D G3DSA:3.30.420.10 3 154 4.2E-46 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 LH59_05025 c6bcefd0622b0a893413a2b24a4e2203 182 SUPERFAMILY SSF53098 1 154 4.3E-50 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily LH59_05025 c6bcefd0622b0a893413a2b24a4e2203 182 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 3 150 2.4E-49 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 LH59_05025 c6bcefd0622b0a893413a2b24a4e2203 182 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 3 153 3.1E-44 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 LH59_05025 c6bcefd0622b0a893413a2b24a4e2203 182 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 1 153 46.516 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 LH59_05025 c6bcefd0622b0a893413a2b24a4e2203 182 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 113 147 - T 14-10-2018 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 LH59_01385 7210df0b7e75fbfadd41a7082a672278 404 Gene3D G3DSA:2.40.30.170 91 325 3.5E-76 T 14-10-2018 LH59_01385 7210df0b7e75fbfadd41a7082a672278 404 SUPERFAMILY SSF111369 100 323 5.1E-23 T 14-10-2018 LH59_01385 7210df0b7e75fbfadd41a7082a672278 404 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 80 393 1.2E-50 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 LH59_01385 7210df0b7e75fbfadd41a7082a672278 404 Gene3D G3DSA:2.40.420.20 81 383 3.5E-76 T 14-10-2018 LH59_01385 7210df0b7e75fbfadd41a7082a672278 404 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 88 319 7.2E-43 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain LH59_01385 7210df0b7e75fbfadd41a7082a672278 404 Gene3D G3DSA:1.10.287.470 139 208 3.5E-76 T 14-10-2018 LH59_01385 7210df0b7e75fbfadd41a7082a672278 404 Gene3D G3DSA:2.40.50.100 105 246 3.5E-76 T 14-10-2018 LH59_08765 0511f8bda54f754fd0ba7e522dda6795 254 Gene3D G3DSA:3.40.50.620 120 216 3.7E-5 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LH59_08765 0511f8bda54f754fd0ba7e522dda6795 254 Pfam PF02698 DUF218 domain 79 244 1.8E-32 T 14-10-2018 IPR003848 Domain of unknown function DUF218 LH59_26295 72b8a19eefe7539d08922dc80773b9e8 321 Pfam PF00348 Polyprenyl synthetase 32 274 2.3E-77 T 14-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 LH59_26295 72b8a19eefe7539d08922dc80773b9e8 321 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 81 95 - T 14-10-2018 IPR033749 Polyprenyl synthetase, conserved site LH59_26295 72b8a19eefe7539d08922dc80773b9e8 321 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 203 215 - T 14-10-2018 IPR033749 Polyprenyl synthetase, conserved site LH59_26295 72b8a19eefe7539d08922dc80773b9e8 321 SUPERFAMILY SSF48576 6 320 6.72E-98 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily LH59_26295 72b8a19eefe7539d08922dc80773b9e8 321 Gene3D G3DSA:1.10.600.10 2 321 1.9E-112 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily LH59_24730 13e979263dd202ca176e2466a7bd9709 225 Hamap MF_01658 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase [coq7]. 24 225 31.731 T 14-10-2018 IPR011566 Ubiquinone biosynthesis protein Coq7 GO:0006744|GO:0055114 Reactome: R-HSA-2142789 LH59_24730 13e979263dd202ca176e2466a7bd9709 225 SUPERFAMILY SSF47240 64 198 1.13E-17 T 14-10-2018 IPR009078 Ferritin-like superfamily LH59_24730 13e979263dd202ca176e2466a7bd9709 225 Pfam PF03232 Ubiquinone biosynthesis protein COQ7 65 224 3.3E-41 T 14-10-2018 IPR011566 Ubiquinone biosynthesis protein Coq7 GO:0006744|GO:0055114 Reactome: R-HSA-2142789 LH59_23325 5bf4da6b8fc1775615efb51a7faee213 400 Gene3D G3DSA:3.30.565.10 260 397 4.4E-18 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_23325 5bf4da6b8fc1775615efb51a7faee213 400 SUPERFAMILY SSF47384 197 244 2.35E-5 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 LH59_23325 5bf4da6b8fc1775615efb51a7faee213 400 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 292 396 8.4E-13 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_23325 5bf4da6b8fc1775615efb51a7faee213 400 Gene3D G3DSA:1.10.287.130 174 256 2.5E-6 T 14-10-2018 LH59_23325 5bf4da6b8fc1775615efb51a7faee213 400 PRINTS PR00344 Bacterial sensor protein C-terminal signature 381 394 1.6E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_23325 5bf4da6b8fc1775615efb51a7faee213 400 PRINTS PR00344 Bacterial sensor protein C-terminal signature 357 375 1.6E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_23325 5bf4da6b8fc1775615efb51a7faee213 400 PRINTS PR00344 Bacterial sensor protein C-terminal signature 327 341 1.6E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_23325 5bf4da6b8fc1775615efb51a7faee213 400 SUPERFAMILY SSF55874 275 395 2.75E-20 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_23325 5bf4da6b8fc1775615efb51a7faee213 400 SMART SM00387 288 397 5.6E-12 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_20850 5cbc278382647b4e142f910a57b771e3 189 SUPERFAMILY SSF51182 61 184 3.24E-17 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_20850 5cbc278382647b4e142f910a57b771e3 189 Pfam PF07883 Cupin domain 116 184 1.6E-9 T 14-10-2018 IPR013096 Cupin 2, conserved barrel LH59_20850 5cbc278382647b4e142f910a57b771e3 189 Pfam PF01381 Helix-turn-helix 22 75 1.2E-13 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LH59_20850 5cbc278382647b4e142f910a57b771e3 189 SMART SM00530 21 76 2.9E-15 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LH59_20850 5cbc278382647b4e142f910a57b771e3 189 SUPERFAMILY SSF47413 14 81 2.65E-17 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 LH59_20850 5cbc278382647b4e142f910a57b771e3 189 Gene3D G3DSA:1.10.260.40 4 84 3.1E-19 T 14-10-2018 LH59_20850 5cbc278382647b4e142f910a57b771e3 189 Gene3D G3DSA:2.60.120.10 106 188 6.8E-16 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_04610 19eb66f671dc5c75166a40be1702ed17 463 Gene3D G3DSA:1.10.40.30 407 463 3.1E-28 T 14-10-2018 LH59_04610 19eb66f671dc5c75166a40be1702ed17 463 Pfam PF00206 Lyase 11 341 4.4E-111 T 14-10-2018 IPR022761 Fumarate lyase, N-terminal LH59_04610 19eb66f671dc5c75166a40be1702ed17 463 TIGRFAM TIGR00979 fumC_II: fumarate hydratase, class II 4 459 6.5E-236 T 14-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 LH59_04610 19eb66f671dc5c75166a40be1702ed17 463 PRINTS PR00149 Fumarate lyase superfamily signature 133 151 2.5E-33 T 14-10-2018 IPR000362 Fumarate lyase family LH59_04610 19eb66f671dc5c75166a40be1702ed17 463 PRINTS PR00149 Fumarate lyase superfamily signature 270 297 2.5E-33 T 14-10-2018 IPR000362 Fumarate lyase family LH59_04610 19eb66f671dc5c75166a40be1702ed17 463 PRINTS PR00149 Fumarate lyase superfamily signature 316 332 2.5E-33 T 14-10-2018 IPR000362 Fumarate lyase family LH59_04610 19eb66f671dc5c75166a40be1702ed17 463 PRINTS PR00149 Fumarate lyase superfamily signature 179 197 2.5E-33 T 14-10-2018 IPR000362 Fumarate lyase family LH59_04610 19eb66f671dc5c75166a40be1702ed17 463 Pfam PF10415 Fumarase C C-terminus 407 460 9.7E-25 T 14-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 LH59_04610 19eb66f671dc5c75166a40be1702ed17 463 Gene3D G3DSA:1.10.275.10 4 137 1.1E-55 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal LH59_04610 19eb66f671dc5c75166a40be1702ed17 463 PRINTS PR00145 Argininosuccinate lyase family signature 132 154 3.4E-6 T 14-10-2018 LH59_04610 19eb66f671dc5c75166a40be1702ed17 463 PRINTS PR00145 Argininosuccinate lyase family signature 316 332 3.4E-6 T 14-10-2018 LH59_04610 19eb66f671dc5c75166a40be1702ed17 463 PRINTS PR00145 Argininosuccinate lyase family signature 174 194 3.4E-6 T 14-10-2018 LH59_04610 19eb66f671dc5c75166a40be1702ed17 463 ProSitePatterns PS00163 Fumarate lyases signature. 316 325 - T 14-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 LH59_04610 19eb66f671dc5c75166a40be1702ed17 463 Gene3D G3DSA:1.20.200.10 138 406 1.1E-115 T 14-10-2018 LH59_04610 19eb66f671dc5c75166a40be1702ed17 463 Hamap MF_00743 Fumarate hydratase class II [fumC]. 3 461 92.397 T 14-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 LH59_04610 19eb66f671dc5c75166a40be1702ed17 463 SUPERFAMILY SSF48557 4 457 2.83E-153 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 LH59_19875 b73ec0a557c5d48b0d4d0de4b01e5075 741 SUPERFAMILY SSF53850 32 691 1.38E-84 T 14-10-2018 LH59_19875 b73ec0a557c5d48b0d4d0de4b01e5075 741 Gene3D G3DSA:3.10.105.10 430 654 2.2E-47 T 14-10-2018 LH59_19875 b73ec0a557c5d48b0d4d0de4b01e5075 741 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 167 601 9.0E-49 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain LH59_00570 c41238f7959efa9910e690fd53eca447 621 Hamap MF_00747 Isocitrate dehydrogenase kinase/phosphatase [aceK]. 15 613 44.493 T 14-10-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 LH59_00570 c41238f7959efa9910e690fd53eca447 621 PIRSF PIRSF000719 15 90 3.0E-16 T 14-10-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 LH59_00570 c41238f7959efa9910e690fd53eca447 621 PIRSF PIRSF000719 102 615 6.9E-207 T 14-10-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 LH59_00570 c41238f7959efa9910e690fd53eca447 621 Pfam PF06315 Isocitrate dehydrogenase kinase/phosphatase (AceK) 23 609 2.2E-247 T 14-10-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 LH59_00570 c41238f7959efa9910e690fd53eca447 621 ProDom PD043552 KINASE KINASE/PHOSPHATASE ISOCITRATE DEHYDROGENASE 3.1.3.- IDH TRANSFERASE IDHK/P HYDROLASE ENZYME 19 611 0.0 T 14-10-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 LH59_11230 778308edbd9e0abc3a6698268794dbfb 283 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 259 267 - T 14-10-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 LH59_11230 778308edbd9e0abc3a6698268794dbfb 283 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 282 39.107 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 LH59_11230 778308edbd9e0abc3a6698268794dbfb 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 203 232 1.2E-81 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 LH59_11230 778308edbd9e0abc3a6698268794dbfb 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 255 273 1.2E-81 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 LH59_11230 778308edbd9e0abc3a6698268794dbfb 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 1.2E-81 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 LH59_11230 778308edbd9e0abc3a6698268794dbfb 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 1.2E-81 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 LH59_11230 778308edbd9e0abc3a6698268794dbfb 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 1.2E-81 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 LH59_11230 778308edbd9e0abc3a6698268794dbfb 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 1.2E-81 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 LH59_11230 778308edbd9e0abc3a6698268794dbfb 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 238 254 1.2E-81 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 LH59_11230 778308edbd9e0abc3a6698268794dbfb 283 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 1.3E-42 T 14-10-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 LH59_11230 778308edbd9e0abc3a6698268794dbfb 283 SUPERFAMILY SSF51735 122 280 1.27E-52 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_11230 778308edbd9e0abc3a6698268794dbfb 283 SUPERFAMILY SSF53223 1 121 2.78E-41 T 14-10-2018 LH59_11230 778308edbd9e0abc3a6698268794dbfb 283 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 281 1.6E-69 T 14-10-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 LH59_11230 778308edbd9e0abc3a6698268794dbfb 283 Gene3D G3DSA:3.40.50.720 6 258 9.8E-114 T 14-10-2018 LH59_11230 778308edbd9e0abc3a6698268794dbfb 283 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 75 100 - T 14-10-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 LH59_11230 778308edbd9e0abc3a6698268794dbfb 283 Gene3D G3DSA:3.40.50.10860 8 276 9.8E-114 T 14-10-2018 LH59_05865 ddf5b627ef41a5976e681a148f31e68a 468 Pfam PF08521 Two-component sensor kinase N-terminal 25 165 1.3E-37 T 14-10-2018 IPR013727 Two-component sensor kinase, N-terminal LH59_05865 ddf5b627ef41a5976e681a148f31e68a 468 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 355 462 6.0E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_05865 ddf5b627ef41a5976e681a148f31e68a 468 Gene3D G3DSA:1.10.287.130 193 305 1.5E-14 T 14-10-2018 LH59_05865 ddf5b627ef41a5976e681a148f31e68a 468 SMART SM00388 241 306 2.9E-10 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_05865 ddf5b627ef41a5976e681a148f31e68a 468 SMART SM00387 355 465 2.3E-28 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_05865 ddf5b627ef41a5976e681a148f31e68a 468 Pfam PF00512 His Kinase A (phospho-acceptor) domain 242 299 8.2E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_05865 ddf5b627ef41a5976e681a148f31e68a 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 393 407 7.6E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_05865 ddf5b627ef41a5976e681a148f31e68a 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 449 462 7.6E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_05865 ddf5b627ef41a5976e681a148f31e68a 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 425 443 7.6E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_05865 ddf5b627ef41a5976e681a148f31e68a 468 SUPERFAMILY SSF47384 224 299 1.06E-12 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 LH59_05865 ddf5b627ef41a5976e681a148f31e68a 468 Gene3D G3DSA:3.30.565.10 308 464 6.1E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_05865 ddf5b627ef41a5976e681a148f31e68a 468 SUPERFAMILY SSF55874 296 463 1.03E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_11265 a41623ef6a6036d83195571ccaaca3fc 302 Gene3D G3DSA:3.40.190.290 91 295 5.9E-61 T 14-10-2018 LH59_11265 a41623ef6a6036d83195571ccaaca3fc 302 Pfam PF03466 LysR substrate binding domain 88 295 2.0E-37 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_11265 a41623ef6a6036d83195571ccaaca3fc 302 SUPERFAMILY SSF53850 89 299 1.99E-40 T 14-10-2018 LH59_11265 a41623ef6a6036d83195571ccaaca3fc 302 SUPERFAMILY SSF46785 4 87 2.62E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_11265 a41623ef6a6036d83195571ccaaca3fc 302 Gene3D G3DSA:1.10.10.10 3 90 5.2E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_11265 a41623ef6a6036d83195571ccaaca3fc 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.9E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_22515 b8db4a7436392de697d597e9ca5af319 215 SUPERFAMILY SSF52833 8 191 3.08E-29 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_22515 b8db4a7436392de697d597e9ca5af319 215 Gene3D G3DSA:3.40.30.10 6 214 8.7E-51 T 14-10-2018 LH59_22515 b8db4a7436392de697d597e9ca5af319 215 Pfam PF01323 DSBA-like thioredoxin domain 12 185 2.2E-7 T 14-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 LH59_25090 4d4faf43c56ec1c981aace2b6edcdbf2 446 ProSitePatterns PS00217 Sugar transport proteins signature 2. 141 166 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 LH59_25090 4d4faf43c56ec1c981aace2b6edcdbf2 446 Gene3D G3DSA:1.20.1250.20 29 445 1.8E-65 T 14-10-2018 LH59_25090 4d4faf43c56ec1c981aace2b6edcdbf2 446 ProSitePatterns PS00216 Sugar transport proteins signature 1. 315 332 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 LH59_25090 4d4faf43c56ec1c981aace2b6edcdbf2 446 Pfam PF07690 Major Facilitator Superfamily 37 406 9.0E-31 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_25090 4d4faf43c56ec1c981aace2b6edcdbf2 446 SUPERFAMILY SSF103473 24 440 2.35E-69 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_18390 c9912996b0521af581aee41e39aa0891 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 3.2E-11 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_18390 c9912996b0521af581aee41e39aa0891 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 3.2E-11 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_18390 c9912996b0521af581aee41e39aa0891 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 3.2E-11 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_18390 c9912996b0521af581aee41e39aa0891 162 Pfam PF13412 Winged helix-turn-helix DNA-binding 5 51 2.2E-17 T 14-10-2018 LH59_18390 c9912996b0521af581aee41e39aa0891 162 SUPERFAMILY SSF54909 64 151 5.77E-16 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel LH59_18390 c9912996b0521af581aee41e39aa0891 162 Pfam PF01037 Lrp/AsnC ligand binding domain 70 130 1.2E-14 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LH59_18390 c9912996b0521af581aee41e39aa0891 162 Gene3D G3DSA:1.10.10.10 1 57 1.5E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_18390 c9912996b0521af581aee41e39aa0891 162 Gene3D G3DSA:3.30.70.920 58 139 2.8E-19 T 14-10-2018 LH59_18390 c9912996b0521af581aee41e39aa0891 162 ProSitePatterns PS00519 AsnC-type HTH domain signature. 22 48 - T 14-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site LH59_18390 c9912996b0521af581aee41e39aa0891 162 SUPERFAMILY SSF46785 4 94 8.47E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_18390 c9912996b0521af581aee41e39aa0891 162 SMART SM00344 4 113 4.5E-36 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 LH59_03655 905f1306f9760f7ce6d8fecf3eda31b3 162 Pfam PF04138 GtrA-like protein 42 156 6.8E-16 T 14-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 LH59_12480 c55f6645c39acf28df3b78ff54632e37 398 Hamap MF_01838 Trans-2-enoyl-CoA reductase [NADH] [fabV]. 1 392 53.796 T 14-10-2018 IPR010758 Trans-2-enoyl-CoA reductase GO:0016491|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 LH59_12480 c55f6645c39acf28df3b78ff54632e37 398 Pfam PF07055 Enoyl reductase FAD binding domain 323 386 3.0E-28 T 14-10-2018 IPR024906 Enoyl reductase FAD binding domain KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 LH59_12480 c55f6645c39acf28df3b78ff54632e37 398 Pfam PF12242 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2 79 1.1E-37 T 14-10-2018 IPR010758 Trans-2-enoyl-CoA reductase GO:0016491|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 LH59_12480 c55f6645c39acf28df3b78ff54632e37 398 Pfam PF12241 Trans-2-enoyl-CoA reductase catalytic region 82 316 8.4E-107 T 14-10-2018 IPR024910 Trans-2-enoyl-CoA reductase catalytic domain, putative KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 LH59_12480 c55f6645c39acf28df3b78ff54632e37 398 Gene3D G3DSA:3.40.50.720 1 398 1.2E-179 T 14-10-2018 LH59_26795 be504df6162cf7eb2464795d4db1e823 448 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 193 215 9.9E-31 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 LH59_26795 be504df6162cf7eb2464795d4db1e823 448 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 372 383 9.9E-31 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 LH59_26795 be504df6162cf7eb2464795d4db1e823 448 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 114 128 9.9E-31 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 LH59_26795 be504df6162cf7eb2464795d4db1e823 448 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 235 255 9.9E-31 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 LH59_26795 be504df6162cf7eb2464795d4db1e823 448 Gene3D G3DSA:1.10.285.10 8 383 1.8E-168 T 14-10-2018 LH59_26795 be504df6162cf7eb2464795d4db1e823 448 Gene3D G3DSA:3.40.50.10860 55 190 1.8E-168 T 14-10-2018 LH59_26795 be504df6162cf7eb2464795d4db1e823 448 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 202 446 1.8E-87 T 14-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 LH59_26795 be504df6162cf7eb2464795d4db1e823 448 Gene3D G3DSA:3.40.50.720 209 373 1.8E-168 T 14-10-2018 LH59_26795 be504df6162cf7eb2464795d4db1e823 448 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 57 184 1.9E-49 T 14-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 LH59_26795 be504df6162cf7eb2464795d4db1e823 448 SMART SM00839 204 446 7.3E-96 T 14-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 LH59_26795 be504df6162cf7eb2464795d4db1e823 448 Gene3D G3DSA:1.10.285.10 384 448 3.6E-10 T 14-10-2018 LH59_26795 be504df6162cf7eb2464795d4db1e823 448 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 122 135 - T 14-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 LH59_26795 be504df6162cf7eb2464795d4db1e823 448 PIRSF PIRSF000185 22 448 5.9E-115 T 14-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 LH59_26795 be504df6162cf7eb2464795d4db1e823 448 SUPERFAMILY SSF51735 202 448 8.47E-76 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_26795 be504df6162cf7eb2464795d4db1e823 448 SUPERFAMILY SSF53223 7 196 9.6E-73 T 14-10-2018 LH59_27845 b30ef07217527afbfc625ac56e33c128 250 Gene3D G3DSA:3.40.50.300 2 245 4.0E-56 T 14-10-2018 LH59_27845 b30ef07217527afbfc625ac56e33c128 250 SUPERFAMILY SSF52540 6 235 5.0E-53 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_27845 b30ef07217527afbfc625ac56e33c128 250 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_27845 b30ef07217527afbfc625ac56e33c128 250 Pfam PF00005 ABC transporter 22 172 1.2E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_27845 b30ef07217527afbfc625ac56e33c128 250 SMART SM00382 31 221 2.1E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_03895 6929912109744cc80113b5e96ff24c8b 103 Gene3D G3DSA:1.10.20.30 1 45 5.8E-12 T 14-10-2018 LH59_03895 6929912109744cc80113b5e96ff24c8b 103 SUPERFAMILY SSF102829 3 97 1.15E-20 T 14-10-2018 IPR036192 Cell division protein ZapA-like superfamily LH59_03895 6929912109744cc80113b5e96ff24c8b 103 Pfam PF05164 Cell division protein ZapA 4 89 3.3E-19 T 14-10-2018 IPR007838 Cell division protein ZapA-like LH59_04640 11e2a486de835e94ec19c3bf3d09f543 373 SUPERFAMILY SSF89796 9 367 1.07E-126 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily LH59_04640 11e2a486de835e94ec19c3bf3d09f543 373 Gene3D G3DSA:3.30.1540.10 231 322 1.4E-132 T 14-10-2018 LH59_04640 11e2a486de835e94ec19c3bf3d09f543 373 Pfam PF02515 CoA-transferase family III 11 368 2.6E-123 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 LH59_04640 11e2a486de835e94ec19c3bf3d09f543 373 Gene3D G3DSA:3.40.50.10540 11 355 1.4E-132 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily LH59_16315 3be887e982d01b30c0a2772804b51085 150 Pfam PF02627 Carboxymuconolactone decarboxylase family 36 122 5.3E-16 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 LH59_16315 3be887e982d01b30c0a2772804b51085 150 Gene3D G3DSA:1.20.1290.10 4 129 8.0E-31 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 LH59_16315 3be887e982d01b30c0a2772804b51085 150 SUPERFAMILY SSF69118 4 126 7.19E-27 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 LH59_08210 0d45efed8509678ad7a696ba75246187 306 Pfam PF03466 LysR substrate binding domain 90 291 1.7E-33 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_08210 0d45efed8509678ad7a696ba75246187 306 Gene3D G3DSA:3.40.190.10 104 288 9.6E-55 T 14-10-2018 LH59_08210 0d45efed8509678ad7a696ba75246187 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.1E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_08210 0d45efed8509678ad7a696ba75246187 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.1E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_08210 0d45efed8509678ad7a696ba75246187 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.1E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_08210 0d45efed8509678ad7a696ba75246187 306 SUPERFAMILY SSF53850 92 293 9.23E-36 T 14-10-2018 LH59_08210 0d45efed8509678ad7a696ba75246187 306 SUPERFAMILY SSF46785 3 83 8.18E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_08210 0d45efed8509678ad7a696ba75246187 306 Gene3D G3DSA:1.10.10.10 7 93 1.2E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_08210 0d45efed8509678ad7a696ba75246187 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 5.3E-20 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_08210 0d45efed8509678ad7a696ba75246187 306 Gene3D G3DSA:3.40.190.10 164 261 9.6E-55 T 14-10-2018 LH59_12740 edaef308d6c3011eb03f83e25bf29e63 470 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 387 399 - T 14-10-2018 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 LH59_12740 edaef308d6c3011eb03f83e25bf29e63 470 SMART SM01230 103 380 5.0E-149 T 14-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 LH59_12740 edaef308d6c3011eb03f83e25bf29e63 470 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 6 469 2.0E-198 T 14-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 LH59_12740 edaef308d6c3011eb03f83e25bf29e63 470 SUPERFAMILY SSF54368 4 98 4.58E-34 T 14-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 LH59_12740 edaef308d6c3011eb03f83e25bf29e63 470 ProSitePatterns PS00180 Glutamine synthetase signature 1. 51 69 - T 14-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 LH59_12740 edaef308d6c3011eb03f83e25bf29e63 470 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 15 96 7.9E-30 T 14-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 LH59_12740 edaef308d6c3011eb03f83e25bf29e63 470 Gene3D G3DSA:3.10.20.70 3 105 1.5E-36 T 14-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 LH59_12740 edaef308d6c3011eb03f83e25bf29e63 470 Pfam PF00120 Glutamine synthetase, catalytic domain 104 467 4.1E-139 T 14-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 LH59_12740 edaef308d6c3011eb03f83e25bf29e63 470 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 260 275 - T 14-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 LH59_12740 edaef308d6c3011eb03f83e25bf29e63 470 SUPERFAMILY SSF55931 103 469 1.86E-139 T 14-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 LH59_12740 edaef308d6c3011eb03f83e25bf29e63 470 Gene3D G3DSA:3.30.590.10 106 458 1.7E-146 T 14-10-2018 LH59_10245 a7e48833aa3618ec2b52199279927d1e 241 Gene3D G3DSA:1.10.10.60 14 66 3.1E-16 T 14-10-2018 LH59_10245 a7e48833aa3618ec2b52199279927d1e 241 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 68 1.6E-14 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_10245 a7e48833aa3618ec2b52199279927d1e 241 SUPERFAMILY SSF48498 93 207 3.62E-20 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily LH59_10245 a7e48833aa3618ec2b52199279927d1e 241 SUPERFAMILY SSF46689 10 94 8.21E-18 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_10245 a7e48833aa3618ec2b52199279927d1e 241 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 5.0E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_10245 a7e48833aa3618ec2b52199279927d1e 241 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 5.0E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_10245 a7e48833aa3618ec2b52199279927d1e 241 ProSitePatterns PS01081 TetR-type HTH domain signature. 37 67 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site LH59_10245 a7e48833aa3618ec2b52199279927d1e 241 Pfam PF08359 YsiA-like protein, C-terminal region 78 202 2.3E-8 T 14-10-2018 IPR013570 Transcription regulator YsiA, C-terminal LH59_10245 a7e48833aa3618ec2b52199279927d1e 241 Gene3D G3DSA:1.10.357.10 67 210 4.6E-25 T 14-10-2018 LH59_19890 8d2c91985818acb6cb9f9f956bac717d 696 Gene3D G3DSA:3.40.50.300 311 635 1.6E-69 T 14-10-2018 LH59_19890 8d2c91985818acb6cb9f9f956bac717d 696 Gene3D G3DSA:1.10.10.160 134 219 2.0E-73 T 14-10-2018 IPR013986 DExx box DNA helicase domain superfamily LH59_19890 8d2c91985818acb6cb9f9f956bac717d 696 SUPERFAMILY SSF52540 13 636 4.07E-125 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_19890 8d2c91985818acb6cb9f9f956bac717d 696 Pfam PF13361 UvrD-like helicase C-terminal domain 566 630 2.3E-19 T 14-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 LH59_19890 8d2c91985818acb6cb9f9f956bac717d 696 Gene3D G3DSA:3.40.50.300 19 302 2.0E-73 T 14-10-2018 LH59_19890 8d2c91985818acb6cb9f9f956bac717d 696 Pfam PF13245 AAA domain 36 286 2.8E-30 T 14-10-2018 LH59_19890 8d2c91985818acb6cb9f9f956bac717d 696 Pfam PF13361 UvrD-like helicase C-terminal domain 307 461 3.2E-18 T 14-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 LH59_19890 8d2c91985818acb6cb9f9f956bac717d 696 Gene3D G3DSA:1.10.486.10 412 556 1.6E-69 T 14-10-2018 LH59_24435 819c43281a18c32286d218c3def020e2 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 256 3.0E-14 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_24435 819c43281a18c32286d218c3def020e2 299 Gene3D G3DSA:1.10.3720.10 62 258 1.1E-28 T 14-10-2018 IPR035906 MetI-like superfamily LH59_24435 819c43281a18c32286d218c3def020e2 299 SUPERFAMILY SSF161098 66 253 6.54E-33 T 14-10-2018 IPR035906 MetI-like superfamily LH59_24435 819c43281a18c32286d218c3def020e2 299 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 20 259 7.8E-82 T 14-10-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 LH59_19165 1be372395df56a5e0dd259f4bf815b46 220 Gene3D G3DSA:3.40.470.10 7 205 4.1E-55 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 LH59_19165 1be372395df56a5e0dd259f4bf815b46 220 SMART SM00986 41 201 4.7E-32 T 14-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 LH59_19165 1be372395df56a5e0dd259f4bf815b46 220 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 27 189 1.2E-38 T 14-10-2018 IPR005273 Uracil-DNA glycosylase family 4 LH59_19165 1be372395df56a5e0dd259f4bf815b46 220 TIGRFAM TIGR03914 UDG_fam_dom: uracil-DNA glycosylase family domain 16 201 9.9E-72 T 14-10-2018 IPR005273 Uracil-DNA glycosylase family 4 LH59_19165 1be372395df56a5e0dd259f4bf815b46 220 Pfam PF03167 Uracil DNA glycosylase superfamily 42 194 3.6E-37 T 14-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 LH59_19165 1be372395df56a5e0dd259f4bf815b46 220 SUPERFAMILY SSF52141 20 199 4.91E-51 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 LH59_19165 1be372395df56a5e0dd259f4bf815b46 220 SMART SM00987 41 201 4.7E-32 T 14-10-2018 LH59_18960 a9bcf9f2574380410d0e95be0a69e4cd 4196 Pfam PF05860 haemagglutination activity domain 159 258 2.2E-19 T 14-10-2018 IPR008638 Filamentous haemagglutinin, N-terminal LH59_18960 a9bcf9f2574380410d0e95be0a69e4cd 4196 Pfam PF12545 Filamentous haemagglutinin family outer membrane protein 3985 4095 1.5E-38 T 14-10-2018 IPR021026 Filamentous haemagglutinin family outer membrane protein, domain of unknown function DUF3739 LH59_18960 a9bcf9f2574380410d0e95be0a69e4cd 4196 SUPERFAMILY SSF51126 163 487 1.57E-30 T 14-10-2018 IPR011050 Pectin lyase fold/virulence factor LH59_18960 a9bcf9f2574380410d0e95be0a69e4cd 4196 SMART SM00912 154 258 1.6E-23 T 14-10-2018 IPR008638 Filamentous haemagglutinin, N-terminal LH59_18960 a9bcf9f2574380410d0e95be0a69e4cd 4196 Gene3D G3DSA:2.160.20.10 768 1041 5.1E-7 T 14-10-2018 IPR012334 Pectin lyase fold LH59_18960 a9bcf9f2574380410d0e95be0a69e4cd 4196 Gene3D G3DSA:2.160.20.10 152 530 2.0E-49 T 14-10-2018 IPR012334 Pectin lyase fold LH59_18960 a9bcf9f2574380410d0e95be0a69e4cd 4196 TIGRFAM TIGR01901 adhes_NPXG: filamentous hemagglutinin family N-terminal domain 179 253 3.1E-19 T 14-10-2018 IPR008638 Filamentous haemagglutinin, N-terminal LH59_02825 da25bf0f531cc0e2cdabfb842bb365d8 499 Gene3D G3DSA:3.20.20.140 63 418 2.3E-179 T 14-10-2018 LH59_02825 da25bf0f531cc0e2cdabfb842bb365d8 499 Gene3D G3DSA:3.30.1490.130 292 348 2.3E-179 T 14-10-2018 IPR023100 D-aminoacylase, insert domain superfamily GO:0016811 LH59_02825 da25bf0f531cc0e2cdabfb842bb365d8 499 Gene3D G3DSA:2.30.40.10 10 465 2.3E-179 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 LH59_02825 da25bf0f531cc0e2cdabfb842bb365d8 499 Pfam PF07969 Amidohydrolase family 54 199 3.0E-16 T 14-10-2018 IPR013108 Amidohydrolase 3 LH59_02825 da25bf0f531cc0e2cdabfb842bb365d8 499 Pfam PF07969 Amidohydrolase family 349 467 5.0E-17 T 14-10-2018 IPR013108 Amidohydrolase 3 LH59_02825 da25bf0f531cc0e2cdabfb842bb365d8 499 SUPERFAMILY SSF51556 64 423 7.23E-78 T 14-10-2018 IPR032466 Metal-dependent hydrolase LH59_02825 da25bf0f531cc0e2cdabfb842bb365d8 499 SUPERFAMILY SSF51338 5 470 1.7E-23 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 LH59_13045 7187cd1f89cf7cc7f3cefb5f39ae4469 151 Pfam PF01037 Lrp/AsnC ligand binding domain 86 138 1.8E-13 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LH59_13045 7187cd1f89cf7cc7f3cefb5f39ae4469 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 6.5E-10 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_13045 7187cd1f89cf7cc7f3cefb5f39ae4469 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 6.5E-10 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_13045 7187cd1f89cf7cc7f3cefb5f39ae4469 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 6.5E-10 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_13045 7187cd1f89cf7cc7f3cefb5f39ae4469 151 Gene3D G3DSA:3.30.70.920 58 136 8.3E-17 T 14-10-2018 LH59_13045 7187cd1f89cf7cc7f3cefb5f39ae4469 151 SUPERFAMILY SSF54909 66 148 9.65E-14 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel LH59_13045 7187cd1f89cf7cc7f3cefb5f39ae4469 151 SUPERFAMILY SSF46785 4 63 1.23E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_13045 7187cd1f89cf7cc7f3cefb5f39ae4469 151 Gene3D G3DSA:1.10.10.10 1 57 6.6E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_13045 7187cd1f89cf7cc7f3cefb5f39ae4469 151 Pfam PF13404 AsnC-type helix-turn-helix domain 4 45 1.4E-13 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_13045 7187cd1f89cf7cc7f3cefb5f39ae4469 151 SMART SM00344 4 110 7.0E-31 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 LH59_13045 7187cd1f89cf7cc7f3cefb5f39ae4469 151 ProSitePatterns PS00519 AsnC-type HTH domain signature. 22 48 - T 14-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site LH59_23075 4929bf71a141897400d4266691356f69 1211 Gene3D G3DSA:3.30.470.130 1 443 7.2E-181 T 14-10-2018 LH59_23075 4929bf71a141897400d4266691356f69 1211 SUPERFAMILY SSF160467 808 900 5.62E-18 T 14-10-2018 LH59_23075 4929bf71a141897400d4266691356f69 1211 SUPERFAMILY SSF56059 83 352 1.29E-68 T 14-10-2018 LH59_23075 4929bf71a141897400d4266691356f69 1211 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 LH59_23075 4929bf71a141897400d4266691356f69 1211 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 152 166 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 LH59_23075 4929bf71a141897400d4266691356f69 1211 Gene3D G3DSA:2.40.50.100 1127 1204 9.6E-22 T 14-10-2018 LH59_23075 4929bf71a141897400d4266691356f69 1211 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 807 1030 4.2E-46 T 14-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D LH59_23075 4929bf71a141897400d4266691356f69 1211 SMART SM00796 806 1039 5.0E-108 T 14-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D LH59_23075 4929bf71a141897400d4266691356f69 1211 SUPERFAMILY SSF52440 2 111 3.96E-44 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily LH59_23075 4929bf71a141897400d4266691356f69 1211 TIGRFAM TIGR02712 urea_carbox: urea carboxylase 2 1202 0.0 T 14-10-2018 IPR014084 Urea carboxylase KEGG: 00220+3.5.1.54+6.3.4.6|KEGG: 00791+3.5.1.54+6.3.4.6|MetaCyc: PWY-5169|MetaCyc: PWY-5703 LH59_23075 4929bf71a141897400d4266691356f69 1211 Pfam PF02785 Biotin carboxylase C-terminal domain 336 440 7.6E-37 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LH59_23075 4929bf71a141897400d4266691356f69 1211 SMART SM00878 336 440 2.0E-59 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LH59_23075 4929bf71a141897400d4266691356f69 1211 Gene3D G3DSA:2.40.100.10 631 778 3.7E-59 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily LH59_23075 4929bf71a141897400d4266691356f69 1211 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 322 2.4E-61 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 LH59_23075 4929bf71a141897400d4266691356f69 1211 Gene3D G3DSA:2.40.100.10 889 1112 7.5E-96 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily LH59_23075 4929bf71a141897400d4266691356f69 1211 SMART SM00797 471 768 1.3E-169 T 14-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B LH59_23075 4929bf71a141897400d4266691356f69 1211 SUPERFAMILY SSF51246 330 442 3.19E-37 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 LH59_23075 4929bf71a141897400d4266691356f69 1211 Pfam PF00364 Biotin-requiring enzyme 1143 1202 4.8E-14 T 14-10-2018 IPR000089 Biotin/lipoyl attachment LH59_23075 4929bf71a141897400d4266691356f69 1211 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 107 1.9E-41 T 14-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LH59_23075 4929bf71a141897400d4266691356f69 1211 SUPERFAMILY SSF50891 923 1055 3.79E-26 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily LH59_23075 4929bf71a141897400d4266691356f69 1211 Gene3D G3DSA:3.30.1360.40 790 885 2.0E-30 T 14-10-2018 LH59_23075 4929bf71a141897400d4266691356f69 1211 SUPERFAMILY SSF50891 632 758 3.53E-32 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily LH59_23075 4929bf71a141897400d4266691356f69 1211 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 1159 1176 - T 14-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LH59_23075 4929bf71a141897400d4266691356f69 1211 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 448 774 5.6E-98 T 14-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B LH59_23075 4929bf71a141897400d4266691356f69 1211 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 472 751 3.2E-89 T 14-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B LH59_23075 4929bf71a141897400d4266691356f69 1211 SUPERFAMILY SSF51230 1127 1202 9.03E-20 T 14-10-2018 IPR011053 Single hybrid motif LH59_26660 7b4c152a4d7db9ae4c9b891fce9b1263 427 Pfam PF00034 Cytochrome c 47 146 4.1E-8 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_26660 7b4c152a4d7db9ae4c9b891fce9b1263 427 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 316 401 1.3E-10 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_26660 7b4c152a4d7db9ae4c9b891fce9b1263 427 SUPERFAMILY SSF46626 43 168 8.12E-25 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_26660 7b4c152a4d7db9ae4c9b891fce9b1263 427 Gene3D G3DSA:1.10.760.10 300 427 3.4E-32 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_26660 7b4c152a4d7db9ae4c9b891fce9b1263 427 Gene3D G3DSA:1.10.760.10 181 298 5.9E-7 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_26660 7b4c152a4d7db9ae4c9b891fce9b1263 427 SUPERFAMILY SSF46626 192 306 5.73E-18 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_26660 7b4c152a4d7db9ae4c9b891fce9b1263 427 PIRSF PIRSF000018 18 427 3.2E-135 T 14-10-2018 IPR014353 Membrane-bound alcohol dehydrogenase, cytochrome c subunit GO:0005506|GO:0016020|GO:0016614|GO:0020037 LH59_26660 7b4c152a4d7db9ae4c9b891fce9b1263 427 Gene3D G3DSA:1.10.760.10 2 153 2.4E-12 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_26660 7b4c152a4d7db9ae4c9b891fce9b1263 427 SUPERFAMILY SSF46626 302 421 5.25E-24 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_10980 bfcbb2084c8caf1fa89b46a4739aa237 800 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 157 798 1.5E-115 T 14-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 LH59_10980 bfcbb2084c8caf1fa89b46a4739aa237 800 Gene3D G3DSA:2.40.170.20 267 800 3.1E-143 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_10980 bfcbb2084c8caf1fa89b46a4739aa237 800 SMART SM00965 61 112 1.4E-9 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 LH59_10980 bfcbb2084c8caf1fa89b46a4739aa237 800 Pfam PF00593 TonB dependent receptor 330 799 3.9E-61 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_10980 bfcbb2084c8caf1fa89b46a4739aa237 800 Gene3D G3DSA:3.55.50.30 30 132 8.5E-23 T 14-10-2018 LH59_10980 bfcbb2084c8caf1fa89b46a4739aa237 800 Gene3D G3DSA:2.170.130.10 133 266 3.8E-37 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily LH59_10980 bfcbb2084c8caf1fa89b46a4739aa237 800 Pfam PF07715 TonB-dependent Receptor Plug Domain 157 256 5.4E-19 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_10980 bfcbb2084c8caf1fa89b46a4739aa237 800 SUPERFAMILY SSF56935 143 800 1.83E-137 T 14-10-2018 LH59_19385 4efaad280b4301b5ce473ac1cd3dc306 1065 Hamap MF_02124 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase [glgE]. 409 1063 44.802 T 14-10-2018 IPR026585 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase GO:0016757 KEGG: 00500+2.4.99.16|MetaCyc: PWY-7900 LH59_19385 4efaad280b4301b5ce473ac1cd3dc306 1065 Gene3D G3DSA:3.20.20.80 604 972 1.8E-163 T 14-10-2018 LH59_19385 4efaad280b4301b5ce473ac1cd3dc306 1065 Gene3D G3DSA:3.20.20.80 84 298 3.9E-15 T 14-10-2018 LH59_19385 4efaad280b4301b5ce473ac1cd3dc306 1065 SUPERFAMILY SSF51445 144 243 1.4E-5 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily LH59_19385 4efaad280b4301b5ce473ac1cd3dc306 1065 Pfam PF00128 Alpha amylase, catalytic domain 627 732 7.8E-6 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 LH59_19385 4efaad280b4301b5ce473ac1cd3dc306 1065 Pfam PF11896 Domain of unknown function (DUF3416) 412 603 4.5E-51 T 14-10-2018 IPR021828 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, domain N/S GO:0004553 KEGG: 00500+2.4.99.16|MetaCyc: PWY-7900 LH59_19385 4efaad280b4301b5ce473ac1cd3dc306 1065 Gene3D G3DSA:2.60.40.1180 974 1064 4.7E-11 T 14-10-2018 IPR013780 Glycosyl hydrolase, all-beta LH59_19385 4efaad280b4301b5ce473ac1cd3dc306 1065 Gene3D G3DSA:2.60.40.10 412 595 7.0E-51 T 14-10-2018 IPR013783 Immunoglobulin-like fold LH59_19385 4efaad280b4301b5ce473ac1cd3dc306 1065 Gene3D G3DSA:1.20.58.280 499 585 7.0E-51 T 14-10-2018 LH59_19385 4efaad280b4301b5ce473ac1cd3dc306 1065 SMART SM00642 613 962 2.0E-5 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 LH59_19385 4efaad280b4301b5ce473ac1cd3dc306 1065 SUPERFAMILY SSF51445 597 969 3.01E-88 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily LH59_11565 0234911c48b765db8c05b9d39a8d652c 462 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 223 444 1.2E-51 T 14-10-2018 IPR010809 Flagellar hook-associated protein 2, C-terminal GO:0007155|GO:0009288 LH59_11565 0234911c48b765db8c05b9d39a8d652c 462 Pfam PF07196 Flagellin hook IN motif 129 183 6.9E-8 T 14-10-2018 IPR010810 Flagellin hook, IN motif GO:0006928|GO:0009288|GO:0044781 LH59_11565 0234911c48b765db8c05b9d39a8d652c 462 Pfam PF02465 Flagellar hook-associated protein 2 N-terminus 11 108 3.5E-16 T 14-10-2018 IPR003481 Flagellar hook-associated protein 2, N-terminal GO:0009424 LH59_00140 b94faf2e3841e4582f0efcc0dc5ec22a 355 Pfam PF13416 Bacterial extracellular solute-binding protein 56 314 3.8E-32 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein LH59_00140 b94faf2e3841e4582f0efcc0dc5ec22a 355 SUPERFAMILY SSF53850 31 351 1.42E-55 T 14-10-2018 LH59_00140 b94faf2e3841e4582f0efcc0dc5ec22a 355 Gene3D G3DSA:3.40.190.10 41 320 1.1E-67 T 14-10-2018 LH59_00140 b94faf2e3841e4582f0efcc0dc5ec22a 355 Gene3D G3DSA:3.40.190.10 137 335 1.1E-67 T 14-10-2018 LH59_10690 1fdae309b5d4a5fff100d183e97b1290 428 Gene3D G3DSA:3.40.50.2300 75 381 3.5E-109 T 14-10-2018 LH59_10690 1fdae309b5d4a5fff100d183e97b1290 428 SUPERFAMILY SSF53822 52 423 7.06E-93 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_10690 1fdae309b5d4a5fff100d183e97b1290 428 Gene3D G3DSA:3.40.50.2300 171 388 3.5E-109 T 14-10-2018 LH59_10690 1fdae309b5d4a5fff100d183e97b1290 428 Pfam PF13458 Periplasmic binding protein 52 388 2.6E-94 T 14-10-2018 IPR028081 Leucine-binding protein domain LH59_01820 537b459affaaa01d6ae247e7d66607b5 343 Pfam PF02885 Glycosyl transferase family, helical bundle domain 8 68 1.1E-10 T 14-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 LH59_01820 537b459affaaa01d6ae247e7d66607b5 343 Pfam PF00591 Glycosyl transferase family, a/b domain 78 327 1.7E-90 T 14-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 LH59_01820 537b459affaaa01d6ae247e7d66607b5 343 SUPERFAMILY SSF47648 5 71 6.02E-16 T 14-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 LH59_01820 537b459affaaa01d6ae247e7d66607b5 343 Gene3D G3DSA:1.20.970.10 1 72 2.1E-30 T 14-10-2018 LH59_01820 537b459affaaa01d6ae247e7d66607b5 343 Gene3D G3DSA:3.40.1030.10 75 342 4.5E-103 T 14-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 LH59_01820 537b459affaaa01d6ae247e7d66607b5 343 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 10 336 1.1E-122 T 14-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 LH59_01820 537b459affaaa01d6ae247e7d66607b5 343 SUPERFAMILY SSF52418 77 340 3.4E-93 T 14-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 LH59_01820 537b459affaaa01d6ae247e7d66607b5 343 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 7 337 36.44 T 14-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 LH59_10465 e9180a7992c45e3c8370db6fdbcb771b 344 Pfam PF03916 Polysulphide reductase, NrfD 12 216 4.8E-15 T 14-10-2018 IPR005614 NrfD family LH59_14340 3895501a32198380ad6407bd8eee1510 312 SUPERFAMILY SSF46785 4 111 2.47E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_14340 3895501a32198380ad6407bd8eee1510 312 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 1.2E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_14340 3895501a32198380ad6407bd8eee1510 312 Gene3D G3DSA:3.40.190.10 91 294 1.9E-63 T 14-10-2018 LH59_14340 3895501a32198380ad6407bd8eee1510 312 Gene3D G3DSA:1.10.10.10 3 88 3.0E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_14340 3895501a32198380ad6407bd8eee1510 312 SUPERFAMILY SSF53850 90 299 1.28E-42 T 14-10-2018 LH59_14340 3895501a32198380ad6407bd8eee1510 312 Pfam PF03466 LysR substrate binding domain 89 296 2.1E-40 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_14340 3895501a32198380ad6407bd8eee1510 312 Gene3D G3DSA:3.40.190.10 163 267 1.9E-63 T 14-10-2018 LH59_05505 b201ac659d6d4ca55106f8d8f2450efb 289 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 287 7.3E-30 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_05505 b201ac659d6d4ca55106f8d8f2450efb 289 Gene3D G3DSA:1.10.3720.10 79 281 2.5E-21 T 14-10-2018 IPR035906 MetI-like superfamily LH59_05505 b201ac659d6d4ca55106f8d8f2450efb 289 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 14 63 1.0E-7 T 14-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain LH59_05505 b201ac659d6d4ca55106f8d8f2450efb 289 SUPERFAMILY SSF161098 81 286 3.27E-27 T 14-10-2018 IPR035906 MetI-like superfamily LH59_14315 1a1ee4da78a76c6cf7adf1c1c4822f4b 308 SUPERFAMILY SSF46785 2 85 6.8E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_14315 1a1ee4da78a76c6cf7adf1c1c4822f4b 308 SUPERFAMILY SSF53850 90 301 4.98E-39 T 14-10-2018 LH59_14315 1a1ee4da78a76c6cf7adf1c1c4822f4b 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 2.8E-13 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_14315 1a1ee4da78a76c6cf7adf1c1c4822f4b 308 Pfam PF03466 LysR substrate binding domain 96 303 1.1E-28 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_14315 1a1ee4da78a76c6cf7adf1c1c4822f4b 308 Gene3D G3DSA:3.40.190.10 90 298 1.6E-58 T 14-10-2018 LH59_14315 1a1ee4da78a76c6cf7adf1c1c4822f4b 308 Gene3D G3DSA:1.10.10.10 1 88 4.0E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_14315 1a1ee4da78a76c6cf7adf1c1c4822f4b 308 Gene3D G3DSA:3.40.190.10 172 274 1.6E-58 T 14-10-2018 LH59_27865 4d26bbfe1fbf0f5afec5a7a97d7aa594 93 PRINTS PR00973 Ribosomal protein S17 family signature 32 55 6.8E-10 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_27865 4d26bbfe1fbf0f5afec5a7a97d7aa594 93 PRINTS PR00973 Ribosomal protein S17 family signature 74 81 6.8E-10 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_27865 4d26bbfe1fbf0f5afec5a7a97d7aa594 93 PRINTS PR00973 Ribosomal protein S17 family signature 64 74 6.8E-10 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_27865 4d26bbfe1fbf0f5afec5a7a97d7aa594 93 Pfam PF00366 Ribosomal protein S17 18 84 8.4E-31 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_27865 4d26bbfe1fbf0f5afec5a7a97d7aa594 93 SUPERFAMILY SSF50249 12 91 9.85E-31 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_27865 4d26bbfe1fbf0f5afec5a7a97d7aa594 93 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 14 84 6.7E-35 T 14-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_27865 4d26bbfe1fbf0f5afec5a7a97d7aa594 93 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 13 88 24.491 T 14-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_27865 4d26bbfe1fbf0f5afec5a7a97d7aa594 93 ProSitePatterns PS00056 Ribosomal protein S17 signature. 64 76 - T 14-10-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27865 4d26bbfe1fbf0f5afec5a7a97d7aa594 93 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 13 84 6.0E-36 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_27865 4d26bbfe1fbf0f5afec5a7a97d7aa594 93 Gene3D G3DSA:2.40.50.140 9 92 2.6E-33 T 14-10-2018 LH59_10365 56e542ce5fd8813b06abbfd875bca762 151 SUPERFAMILY SSF88946 1 81 1.61E-10 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 LH59_10365 56e542ce5fd8813b06abbfd875bca762 151 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 3 145 1.9E-18 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 LH59_10365 56e542ce5fd8813b06abbfd875bca762 151 Pfam PF04542 Sigma-70 region 2 2 63 5.9E-8 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 LH59_10365 56e542ce5fd8813b06abbfd875bca762 151 SUPERFAMILY SSF88659 87 146 5.76E-15 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like LH59_10365 56e542ce5fd8813b06abbfd875bca762 151 Gene3D G3DSA:1.10.1740.10 1 60 2.4E-5 T 14-10-2018 LH59_10365 56e542ce5fd8813b06abbfd875bca762 151 Pfam PF08281 Sigma-70, region 4 95 146 1.7E-17 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LH59_10365 56e542ce5fd8813b06abbfd875bca762 151 Gene3D G3DSA:1.10.10.10 71 149 1.1E-13 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_23330 026c40b64b36121378b6a333ee783250 183 Gene3D G3DSA:3.40.50.2300 8 120 3.5E-25 T 14-10-2018 LH59_23330 026c40b64b36121378b6a333ee783250 183 SUPERFAMILY SSF52172 8 145 3.37E-28 T 14-10-2018 IPR011006 CheY-like superfamily LH59_23330 026c40b64b36121378b6a333ee783250 183 Gene3D G3DSA:1.10.10.60 121 175 2.1E-21 T 14-10-2018 LH59_23330 026c40b64b36121378b6a333ee783250 183 SMART SM00448 7 116 2.0E-16 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_23330 026c40b64b36121378b6a333ee783250 183 Pfam PF00072 Response regulator receiver domain 8 111 1.2E-18 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_23330 026c40b64b36121378b6a333ee783250 183 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 139 156 2.5E-8 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 LH59_23330 026c40b64b36121378b6a333ee783250 183 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 156 176 2.5E-8 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 LH59_23330 026c40b64b36121378b6a333ee783250 183 Pfam PF02954 Bacterial regulatory protein, Fis family 136 172 6.5E-13 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 LH59_01460 b321bb67a55fad3c49ad4a6184ec6143 509 Gene3D G3DSA:1.20.200.10 197 508 2.9E-124 T 14-10-2018 LH59_01460 b321bb67a55fad3c49ad4a6184ec6143 509 Hamap MF_00229 Histidine ammonia-lyase [hutH]. 2 503 44.042 T 14-10-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 LH59_01460 b321bb67a55fad3c49ad4a6184ec6143 509 SUPERFAMILY SSF48557 3 506 1.57E-189 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 LH59_01460 b321bb67a55fad3c49ad4a6184ec6143 509 Pfam PF00221 Aromatic amino acid lyase 10 469 2.7E-184 T 14-10-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 LH59_01460 b321bb67a55fad3c49ad4a6184ec6143 509 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 4 503 8.6E-218 T 14-10-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 LH59_01460 b321bb67a55fad3c49ad4a6184ec6143 509 Gene3D G3DSA:1.10.275.10 1 196 2.1E-68 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal LH59_01460 b321bb67a55fad3c49ad4a6184ec6143 509 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 138 154 - T 14-10-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 LH59_14755 1a87b81f38e556a2b163a4e13f056b02 287 SUPERFAMILY SSF103481 182 282 1.31E-9 T 14-10-2018 LH59_14755 1a87b81f38e556a2b163a4e13f056b02 287 Pfam PF00892 EamA-like transporter family 6 134 2.0E-11 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_14755 1a87b81f38e556a2b163a4e13f056b02 287 Pfam PF00892 EamA-like transporter family 148 280 2.6E-14 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_14755 1a87b81f38e556a2b163a4e13f056b02 287 SUPERFAMILY SSF103481 41 135 9.94E-7 T 14-10-2018 LH59_04055 5e66d169b0f8a89cf9d7c773978e746b 316 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 248 276 - T 14-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 LH59_04055 5e66d169b0f8a89cf9d7c773978e746b 316 PIRSF PIRSF039102 3 50 1.2E-7 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 LH59_04055 5e66d169b0f8a89cf9d7c773978e746b 316 PIRSF PIRSF039102 44 314 1.9E-86 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 LH59_04055 5e66d169b0f8a89cf9d7c773978e746b 316 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 7 305 9.3E-98 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 LH59_04055 5e66d169b0f8a89cf9d7c773978e746b 316 Gene3D G3DSA:3.40.50.20 1 87 1.2E-30 T 14-10-2018 LH59_04055 5e66d169b0f8a89cf9d7c773978e746b 316 Pfam PF01820 D-ala D-ala ligase N-terminus 7 89 1.9E-18 T 14-10-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 LH59_04055 5e66d169b0f8a89cf9d7c773978e746b 316 SMART SM01209 98 273 0.0072 T 14-10-2018 LH59_04055 5e66d169b0f8a89cf9d7c773978e746b 316 SUPERFAMILY SSF56059 99 308 6.9E-59 T 14-10-2018 LH59_04055 5e66d169b0f8a89cf9d7c773978e746b 316 Gene3D G3DSA:3.30.1490.20 114 179 8.2E-75 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 LH59_04055 5e66d169b0f8a89cf9d7c773978e746b 316 SUPERFAMILY SSF52440 7 99 7.19E-30 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily LH59_04055 5e66d169b0f8a89cf9d7c773978e746b 316 Gene3D G3DSA:3.30.470.20 88 301 8.2E-75 T 14-10-2018 LH59_04055 5e66d169b0f8a89cf9d7c773978e746b 316 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 6 306 35.992 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 LH59_04055 5e66d169b0f8a89cf9d7c773978e746b 316 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 66 77 - T 14-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 LH59_04055 5e66d169b0f8a89cf9d7c773978e746b 316 Pfam PF07478 D-ala D-ala ligase C-terminus 107 302 1.6E-56 T 14-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 LH59_11600 fb25a7e550707cdf49b6439f18532c84 436 TIGRFAM TIGR01499 folC: bifunctional protein FolC 33 430 1.1E-98 T 14-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 LH59_11600 fb25a7e550707cdf49b6439f18532c84 436 SUPERFAMILY SSF53623 12 289 7.33E-87 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 LH59_11600 fb25a7e550707cdf49b6439f18532c84 436 SUPERFAMILY SSF53244 291 431 4.03E-31 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 LH59_11600 fb25a7e550707cdf49b6439f18532c84 436 Gene3D G3DSA:3.40.1190.10 3 292 2.9E-89 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 LH59_11600 fb25a7e550707cdf49b6439f18532c84 436 Gene3D G3DSA:3.90.190.20 293 435 1.7E-30 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 LH59_11600 fb25a7e550707cdf49b6439f18532c84 436 Pfam PF08245 Mur ligase middle domain 53 267 1.3E-11 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 LH59_11600 fb25a7e550707cdf49b6439f18532c84 436 PIRSF PIRSF001563 8 436 2.5E-103 T 14-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 LH59_16695 258322009a35deb6d37251d7b98a038a 820 Pfam PF13567 Domain of unknown function (DUF4131) 27 194 4.9E-17 T 14-10-2018 IPR025405 Domain of unknown function DUF4131 LH59_16695 258322009a35deb6d37251d7b98a038a 820 Pfam PF00753 Metallo-beta-lactamase superfamily 553 755 8.4E-12 T 14-10-2018 IPR001279 Metallo-beta-lactamase LH59_16695 258322009a35deb6d37251d7b98a038a 820 SUPERFAMILY SSF56281 544 817 6.36E-45 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like LH59_16695 258322009a35deb6d37251d7b98a038a 820 Pfam PF03772 Competence protein 236 517 1.6E-55 T 14-10-2018 IPR004477 ComEC/Rec2-related protein LH59_16695 258322009a35deb6d37251d7b98a038a 820 Gene3D G3DSA:3.60.15.10 546 804 1.2E-45 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like LH59_16695 258322009a35deb6d37251d7b98a038a 820 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 257 448 1.2E-20 T 14-10-2018 IPR004477 ComEC/Rec2-related protein LH59_16695 258322009a35deb6d37251d7b98a038a 820 SMART SM00849 556 764 6.0E-16 T 14-10-2018 IPR001279 Metallo-beta-lactamase LH59_16695 258322009a35deb6d37251d7b98a038a 820 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 151 793 2.2E-90 T 14-10-2018 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 LH59_04155 234498738a0d41da25726adc6f77cd27 298 Pfam PF03466 LysR substrate binding domain 88 291 9.1E-43 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_04155 234498738a0d41da25726adc6f77cd27 298 Gene3D G3DSA:3.40.190.290 91 295 6.2E-45 T 14-10-2018 LH59_04155 234498738a0d41da25726adc6f77cd27 298 Gene3D G3DSA:1.10.10.10 3 86 1.4E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_04155 234498738a0d41da25726adc6f77cd27 298 SUPERFAMILY SSF53850 90 290 1.9E-38 T 14-10-2018 LH59_04155 234498738a0d41da25726adc6f77cd27 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.1E-21 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_04155 234498738a0d41da25726adc6f77cd27 298 SUPERFAMILY SSF46785 1 111 1.19E-25 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_04155 234498738a0d41da25726adc6f77cd27 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.6E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_04155 234498738a0d41da25726adc6f77cd27 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.6E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_04155 234498738a0d41da25726adc6f77cd27 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.6E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_11195 9acad7cb314e38e40b442316c731ed1a 397 Gene3D G3DSA:1.10.287.470 99 172 2.5E-112 T 14-10-2018 LH59_11195 9acad7cb314e38e40b442316c731ed1a 397 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 64 295 4.8E-14 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain LH59_11195 9acad7cb314e38e40b442316c731ed1a 397 Gene3D G3DSA:2.40.30.170 50 305 2.5E-112 T 14-10-2018 LH59_11195 9acad7cb314e38e40b442316c731ed1a 397 Gene3D G3DSA:2.40.50.100 64 208 2.5E-112 T 14-10-2018 LH59_11195 9acad7cb314e38e40b442316c731ed1a 397 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 40 377 2.1E-81 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 LH59_11195 9acad7cb314e38e40b442316c731ed1a 397 Gene3D G3DSA:2.40.420.20 306 375 2.5E-112 T 14-10-2018 LH59_11195 9acad7cb314e38e40b442316c731ed1a 397 SUPERFAMILY SSF111369 52 302 1.83E-86 T 14-10-2018 LH59_21120 bb097590a0f0f959059d2683b34fa5dd 422 Pfam PF00202 Aminotransferase class-III 22 416 8.7E-114 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LH59_21120 bb097590a0f0f959059d2683b34fa5dd 422 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 237 274 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LH59_21120 bb097590a0f0f959059d2683b34fa5dd 422 SUPERFAMILY SSF53383 5 418 9.25E-123 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_21120 bb097590a0f0f959059d2683b34fa5dd 422 PIRSF PIRSF000521 165 420 3.7E-23 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LH59_21120 bb097590a0f0f959059d2683b34fa5dd 422 PIRSF PIRSF000521 18 161 2.8E-7 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LH59_21120 bb097590a0f0f959059d2683b34fa5dd 422 Gene3D G3DSA:3.90.1150.10 11 411 1.1E-151 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_21120 bb097590a0f0f959059d2683b34fa5dd 422 Gene3D G3DSA:3.40.640.10 62 326 1.1E-151 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_21120 bb097590a0f0f959059d2683b34fa5dd 422 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 14 417 4.2E-162 T 14-10-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 LH59_04975 d8ee2cdf1c11eee3638a763d99d19691 447 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 8 435 5.0E-93 T 14-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 LH59_04975 d8ee2cdf1c11eee3638a763d99d19691 447 PIRSF PIRSF006446 1 441 1.7E-92 T 14-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 LH59_18485 17a7b27825ba34b7f4540db8eac18dff 462 SUPERFAMILY SSF53187 48 456 1.11E-84 T 14-10-2018 LH59_18485 17a7b27825ba34b7f4540db8eac18dff 462 Gene3D G3DSA:3.30.70.360 246 361 7.9E-141 T 14-10-2018 LH59_18485 17a7b27825ba34b7f4540db8eac18dff 462 PIRSF PIRSF005962 45 459 2.5E-121 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 LH59_18485 17a7b27825ba34b7f4540db8eac18dff 462 Gene3D G3DSA:3.40.630.10 60 439 7.9E-141 T 14-10-2018 LH59_18485 17a7b27825ba34b7f4540db8eac18dff 462 Pfam PF01546 Peptidase family M20/M25/M40 118 450 3.8E-32 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 LH59_18485 17a7b27825ba34b7f4540db8eac18dff 462 SUPERFAMILY SSF55031 249 356 1.57E-29 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain LH59_18485 17a7b27825ba34b7f4540db8eac18dff 462 Pfam PF07687 Peptidase dimerisation domain 250 346 3.3E-12 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain LH59_18485 17a7b27825ba34b7f4540db8eac18dff 462 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 60 441 1.0E-107 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 LH59_04025 c8ad94c02e6cfa98685bcdeb7b29f14f 954 Pfam PF01225 Mur ligase family, catalytic domain 515 562 7.4E-6 T 14-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 LH59_04025 c8ad94c02e6cfa98685bcdeb7b29f14f 954 Pfam PF01225 Mur ligase family, catalytic domain 30 108 1.9E-10 T 14-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 LH59_04025 c8ad94c02e6cfa98685bcdeb7b29f14f 954 SUPERFAMILY SSF53623 111 342 4.97E-69 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 LH59_04025 c8ad94c02e6cfa98685bcdeb7b29f14f 954 SUPERFAMILY SSF63418 29 109 7.46E-18 T 14-10-2018 IPR035911 MurE/MurF, N-terminal LH59_04025 c8ad94c02e6cfa98685bcdeb7b29f14f 954 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 30 510 3.7E-141 T 14-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 LH59_04025 c8ad94c02e6cfa98685bcdeb7b29f14f 954 Gene3D G3DSA:3.40.1190.10 573 804 1.0E-69 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 LH59_04025 c8ad94c02e6cfa98685bcdeb7b29f14f 954 Gene3D G3DSA:3.90.190.20 806 941 3.8E-42 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 LH59_04025 c8ad94c02e6cfa98685bcdeb7b29f14f 954 Gene3D G3DSA:3.90.190.20 360 509 3.1E-53 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 LH59_04025 c8ad94c02e6cfa98685bcdeb7b29f14f 954 SUPERFAMILY SSF53244 807 937 2.01E-36 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 LH59_04025 c8ad94c02e6cfa98685bcdeb7b29f14f 954 SUPERFAMILY SSF53623 591 806 1.57E-52 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 LH59_04025 c8ad94c02e6cfa98685bcdeb7b29f14f 954 Gene3D G3DSA:3.40.1190.10 111 349 5.9E-75 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 LH59_04025 c8ad94c02e6cfa98685bcdeb7b29f14f 954 Pfam PF08245 Mur ligase middle domain 597 786 1.1E-39 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 LH59_04025 c8ad94c02e6cfa98685bcdeb7b29f14f 954 Pfam PF08245 Mur ligase middle domain 120 325 1.5E-46 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 LH59_04025 c8ad94c02e6cfa98685bcdeb7b29f14f 954 Pfam PF02875 Mur ligase family, glutamate ligase domain 807 890 5.3E-17 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 LH59_04025 c8ad94c02e6cfa98685bcdeb7b29f14f 954 Pfam PF02875 Mur ligase family, glutamate ligase domain 348 443 3.6E-18 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 LH59_04025 c8ad94c02e6cfa98685bcdeb7b29f14f 954 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 520 937 4.8E-126 T 14-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 LH59_04025 c8ad94c02e6cfa98685bcdeb7b29f14f 954 SUPERFAMILY SSF63418 513 587 1.44E-19 T 14-10-2018 IPR035911 MurE/MurF, N-terminal LH59_04025 c8ad94c02e6cfa98685bcdeb7b29f14f 954 SUPERFAMILY SSF53244 346 510 1.25E-41 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 LH59_04025 c8ad94c02e6cfa98685bcdeb7b29f14f 954 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 1 510 32.212 T 14-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 LH59_04025 c8ad94c02e6cfa98685bcdeb7b29f14f 954 Gene3D G3DSA:3.40.1390.10 510 572 3.5E-21 T 14-10-2018 LH59_04025 c8ad94c02e6cfa98685bcdeb7b29f14f 954 Gene3D G3DSA:3.40.1390.10 13 110 1.6E-19 T 14-10-2018 LH59_04025 c8ad94c02e6cfa98685bcdeb7b29f14f 954 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 488 938 31.86 T 14-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 LH59_01335 e0def59aaf7af55b54705c74b0c0422b 320 Gene3D G3DSA:3.60.110.10 8 307 5.4E-101 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily LH59_01335 e0def59aaf7af55b54705c74b0c0422b 320 Pfam PF00795 Carbon-nitrogen hydrolase 13 286 3.5E-48 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 LH59_01335 e0def59aaf7af55b54705c74b0c0422b 320 SUPERFAMILY SSF56317 9 307 1.7E-71 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily LH59_17965 fee678afe0d8722e97f922f3e538a7af 254 Gene3D G3DSA:3.90.550.10 1 250 2.8E-94 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases LH59_17965 fee678afe0d8722e97f922f3e538a7af 254 Hamap MF_00057 8-amino-3,8-dideoxy-manno-octulosonate cytidylyltransferase [kdsB]. 1 251 40.364 T 14-10-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 LH59_17965 fee678afe0d8722e97f922f3e538a7af 254 TIGRFAM TIGR00466 kdsB: 3-deoxy-D-manno-octulosonate cytidylyltransferase 2 244 1.7E-79 T 14-10-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 LH59_17965 fee678afe0d8722e97f922f3e538a7af 254 Pfam PF02348 Cytidylyltransferase 4 221 4.2E-52 T 14-10-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 LH59_17965 fee678afe0d8722e97f922f3e538a7af 254 SUPERFAMILY SSF53448 3 253 7.74E-63 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases LH59_23240 00326067a95d6c1d6bafa66c24f3ff25 377 Gene3D G3DSA:3.40.50.1100 97 191 4.0E-95 T 14-10-2018 LH59_23240 00326067a95d6c1d6bafa66c24f3ff25 377 Gene3D G3DSA:3.40.50.1100 52 366 4.0E-95 T 14-10-2018 LH59_23240 00326067a95d6c1d6bafa66c24f3ff25 377 SUPERFAMILY SSF53686 45 370 1.31E-79 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme LH59_23240 00326067a95d6c1d6bafa66c24f3ff25 377 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 66 361 6.7E-65 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme LH59_13875 1451d805ad94c35c902dd2fa8fe2d2bd 689 Gene3D G3DSA:2.170.130.10 45 157 2.6E-15 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily LH59_13875 1451d805ad94c35c902dd2fa8fe2d2bd 689 Gene3D G3DSA:2.40.170.20 163 688 2.0E-74 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_13875 1451d805ad94c35c902dd2fa8fe2d2bd 689 TIGRFAM TIGR01778 TonB-copper: TonB-dependent copper receptor 52 689 1.4E-271 T 14-10-2018 IPR010100 TonB-dependent copper receptor LH59_13875 1451d805ad94c35c902dd2fa8fe2d2bd 689 Pfam PF00593 TonB dependent receptor 205 688 2.2E-48 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_13875 1451d805ad94c35c902dd2fa8fe2d2bd 689 Pfam PF07715 TonB-dependent Receptor Plug Domain 48 151 1.8E-14 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_13875 1451d805ad94c35c902dd2fa8fe2d2bd 689 SUPERFAMILY SSF56935 37 688 1.74E-96 T 14-10-2018 LH59_15980 7ceae794d217a6d1f80a7b700b4c758b 312 Gene3D G3DSA:1.10.10.60 186 296 7.5E-25 T 14-10-2018 LH59_15980 7ceae794d217a6d1f80a7b700b4c758b 312 Pfam PF06719 AraC-type transcriptional regulator N-terminus 29 178 2.0E-46 T 14-10-2018 IPR009594 Transcription regulator HTH, AraC, N-terminal LH59_15980 7ceae794d217a6d1f80a7b700b4c758b 312 SMART SM00342 207 290 3.0E-20 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_15980 7ceae794d217a6d1f80a7b700b4c758b 312 SUPERFAMILY SSF46689 243 295 9.41E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_15980 7ceae794d217a6d1f80a7b700b4c758b 312 Pfam PF12833 Helix-turn-helix domain 213 289 8.6E-20 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_15980 7ceae794d217a6d1f80a7b700b4c758b 312 SUPERFAMILY SSF46689 190 241 1.9E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_03785 112e2c1432c2bf08f164bd2efc80a3e5 347 Pfam PF01032 FecCD transport family 30 343 4.2E-84 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 LH59_03785 112e2c1432c2bf08f164bd2efc80a3e5 347 PRINTS PR00173 Glutamate-aspartate symporter signature 19 39 3.1E-5 T 14-10-2018 LH59_03785 112e2c1432c2bf08f164bd2efc80a3e5 347 PRINTS PR00173 Glutamate-aspartate symporter signature 321 347 3.1E-5 T 14-10-2018 LH59_03785 112e2c1432c2bf08f164bd2efc80a3e5 347 PRINTS PR00173 Glutamate-aspartate symporter signature 156 178 3.1E-5 T 14-10-2018 LH59_03785 112e2c1432c2bf08f164bd2efc80a3e5 347 SUPERFAMILY SSF81345 11 343 2.09E-78 T 14-10-2018 IPR037294 ABC transporter, BtuC-like LH59_03785 112e2c1432c2bf08f164bd2efc80a3e5 347 Gene3D G3DSA:1.10.3470.10 15 346 7.4E-95 T 14-10-2018 IPR037294 ABC transporter, BtuC-like LH59_24825 4878be6cb681d151ca2215c10c08e5bc 366 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 268 353 1.6E-14 T 14-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 LH59_24825 4878be6cb681d151ca2215c10c08e5bc 366 PIRSF PIRSF006487 1 366 1.5E-82 T 14-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 LH59_24825 4878be6cb681d151ca2215c10c08e5bc 366 Gene3D G3DSA:2.40.30.110 282 366 3.5E-28 T 14-10-2018 LH59_24825 4878be6cb681d151ca2215c10c08e5bc 366 Gene3D G3DSA:3.30.70.1400 54 143 9.5E-83 T 14-10-2018 LH59_24825 4878be6cb681d151ca2215c10c08e5bc 366 Hamap MF_00259 Aminomethyltransferase [gcvT]. 4 359 43.354 T 14-10-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 LH59_24825 4878be6cb681d151ca2215c10c08e5bc 366 Pfam PF01571 Aminomethyltransferase folate-binding domain 11 258 3.5E-88 T 14-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain LH59_24825 4878be6cb681d151ca2215c10c08e5bc 366 Gene3D G3DSA:3.30.1360.120 9 236 9.5E-83 T 14-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 LH59_24825 4878be6cb681d151ca2215c10c08e5bc 366 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 5 359 5.2E-121 T 14-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 LH59_24825 4878be6cb681d151ca2215c10c08e5bc 366 Gene3D G3DSA:4.10.1250.10 237 278 8.4E-19 T 14-10-2018 LH59_24825 4878be6cb681d151ca2215c10c08e5bc 366 SUPERFAMILY SSF103025 4 277 1.73E-92 T 14-10-2018 LH59_24825 4878be6cb681d151ca2215c10c08e5bc 366 SUPERFAMILY SSF101790 282 361 8.5E-23 T 14-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal LH59_24755 fe3635378c874777ae94ea37e16ac61f 472 Pfam PF00155 Aminotransferase class I and II 147 455 2.8E-33 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LH59_24755 fe3635378c874777ae94ea37e16ac61f 472 Gene3D G3DSA:3.40.640.10 150 366 5.6E-79 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_24755 fe3635378c874777ae94ea37e16ac61f 472 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 79 3.6E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_24755 fe3635378c874777ae94ea37e16ac61f 472 SUPERFAMILY SSF46785 13 83 8.66E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_24755 fe3635378c874777ae94ea37e16ac61f 472 SMART SM00345 20 79 2.1E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_24755 fe3635378c874777ae94ea37e16ac61f 472 Gene3D G3DSA:3.90.1150.10 126 458 5.6E-79 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_24755 fe3635378c874777ae94ea37e16ac61f 472 SUPERFAMILY SSF53383 116 460 1.63E-74 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_24755 fe3635378c874777ae94ea37e16ac61f 472 Gene3D G3DSA:1.10.10.10 15 96 1.5E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_11705 448d1fcc9974176a9d0a51865399e140 264 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 106 135 5.7E-7 T 14-10-2018 IPR001451 Hexapeptide repeat LH59_11705 448d1fcc9974176a9d0a51865399e140 264 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 14 42 1.9E-6 T 14-10-2018 IPR001451 Hexapeptide repeat LH59_11705 448d1fcc9974176a9d0a51865399e140 264 TIGRFAM TIGR01852 lipid_A_lpxA: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase 5 261 4.2E-97 T 14-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 LH59_11705 448d1fcc9974176a9d0a51865399e140 264 SUPERFAMILY SSF51161 5 248 3.14E-76 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily LH59_11705 448d1fcc9974176a9d0a51865399e140 264 Gene3D G3DSA:1.20.1180.10 194 263 4.4E-22 T 14-10-2018 IPR037157 UDP-N-acetylglucosamine O-acyltransferase, C-terminal domain superfamily KEGG: 00540+2.3.1.129 LH59_11705 448d1fcc9974176a9d0a51865399e140 264 Hamap MF_00387 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase [lpxA]. 2 263 44.722 T 14-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 LH59_11705 448d1fcc9974176a9d0a51865399e140 264 Gene3D G3DSA:2.160.10.10 2 193 6.7E-51 T 14-10-2018 LH59_11705 448d1fcc9974176a9d0a51865399e140 264 Pfam PF13720 Udp N-acetylglucosamine O-acyltransferase; Domain 2 177 262 1.7E-26 T 14-10-2018 IPR029098 UDP N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00540+2.3.1.129 LH59_11705 448d1fcc9974176a9d0a51865399e140 264 PIRSF PIRSF000456 1 264 5.5E-97 T 14-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 LH59_04490 5a85effd009d75f9b39dbe4557e6e9db 317 Pfam PF03060 Nitronate monooxygenase 11 305 1.4E-25 T 14-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 LH59_04490 5a85effd009d75f9b39dbe4557e6e9db 317 Gene3D G3DSA:3.20.20.70 2 315 2.4E-72 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_04490 5a85effd009d75f9b39dbe4557e6e9db 317 SUPERFAMILY SSF51412 8 292 3.97E-61 T 14-10-2018 LH59_01915 c53d5e0236afc6f155a2118e7ecda843 229 SMART SM00382 26 215 1.4E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_01915 c53d5e0236afc6f155a2118e7ecda843 229 Pfam PF00005 ABC transporter 18 158 5.1E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_01915 c53d5e0236afc6f155a2118e7ecda843 229 Gene3D G3DSA:3.40.50.300 1 226 7.7E-59 T 14-10-2018 LH59_01915 c53d5e0236afc6f155a2118e7ecda843 229 TIGRFAM TIGR03410 urea_trans_UrtE: urea ABC transporter, ATP-binding protein UrtE 3 229 3.4E-98 T 14-10-2018 IPR017780 ABC transporter, urea, ATP-binding protein, UrtE LH59_01915 c53d5e0236afc6f155a2118e7ecda843 229 SUPERFAMILY SSF52540 2 216 2.45E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_05010 028629b7b70bd936ecb0fdc881dba9a9 321 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 19 307 1.4E-70 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme LH59_05010 028629b7b70bd936ecb0fdc881dba9a9 321 Gene3D G3DSA:3.40.50.1100 54 150 1.1E-113 T 14-10-2018 LH59_05010 028629b7b70bd936ecb0fdc881dba9a9 321 SUPERFAMILY SSF53686 7 314 1.96E-90 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme LH59_05010 028629b7b70bd936ecb0fdc881dba9a9 321 Gene3D G3DSA:3.40.50.1100 16 311 1.1E-113 T 14-10-2018 LH59_05275 3f47864b4ee23c06aad7cfa092d3626f 139 Gene3D G3DSA:1.10.10.10 1 83 2.0E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_05275 3f47864b4ee23c06aad7cfa092d3626f 139 SUPERFAMILY SSF46785 5 133 7.32E-43 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_05275 3f47864b4ee23c06aad7cfa092d3626f 139 Gene3D G3DSA:3.30.1490.190 85 138 4.6E-26 T 14-10-2018 LH59_05275 3f47864b4ee23c06aad7cfa092d3626f 139 Pfam PF01475 Ferric uptake regulator family 10 129 5.4E-47 T 14-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 LH59_04475 bb7d5c68cef680cc650486192cc9cb31 304 SUPERFAMILY SSF51735 6 261 6.26E-65 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_04475 bb7d5c68cef680cc650486192cc9cb31 304 Gene3D G3DSA:3.40.50.720 4 293 4.4E-72 T 14-10-2018 LH59_04475 bb7d5c68cef680cc650486192cc9cb31 304 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 249 4.0E-43 T 14-10-2018 LH59_04475 bb7d5c68cef680cc650486192cc9cb31 304 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 204 3.6E-7 T 14-10-2018 LH59_04475 bb7d5c68cef680cc650486192cc9cb31 304 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 153 1.9E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_04475 bb7d5c68cef680cc650486192cc9cb31 304 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 92 103 1.9E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_04475 bb7d5c68cef680cc650486192cc9cb31 304 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 165 184 1.9E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_04475 bb7d5c68cef680cc650486192cc9cb31 304 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 152 180 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LH59_04475 bb7d5c68cef680cc650486192cc9cb31 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 1.2E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_04475 bb7d5c68cef680cc650486192cc9cb31 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 1.2E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_04475 bb7d5c68cef680cc650486192cc9cb31 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 1.2E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_04475 bb7d5c68cef680cc650486192cc9cb31 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 1.2E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_04475 bb7d5c68cef680cc650486192cc9cb31 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 203 1.2E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_04475 bb7d5c68cef680cc650486192cc9cb31 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.2E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_07775 24bf7f36f8e83eaae25e3e70827b7ba0 322 Gene3D G3DSA:3.40.190.150 27 308 5.1E-106 T 14-10-2018 LH59_07775 24bf7f36f8e83eaae25e3e70827b7ba0 322 PIRSF PIRSF017082 4 322 3.5E-74 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_07775 24bf7f36f8e83eaae25e3e70827b7ba0 322 SUPERFAMILY SSF53850 114 284 3.77E-13 T 14-10-2018 LH59_07775 24bf7f36f8e83eaae25e3e70827b7ba0 322 Gene3D G3DSA:3.40.190.10 124 247 5.1E-106 T 14-10-2018 LH59_07775 24bf7f36f8e83eaae25e3e70827b7ba0 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 318 3.6E-84 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_26185 a46a90225891bef27bd3f03112bed20a 363 Pfam PF10994 Protein of unknown function (DUF2817) 8 347 1.4E-120 T 14-10-2018 IPR021259 Protein of unknown function DUF2817 LH59_26185 a46a90225891bef27bd3f03112bed20a 363 SUPERFAMILY SSF53187 54 318 4.81E-16 T 14-10-2018 LH59_21020 6bb3a34febabcf1a7d58abecf8cef95c 229 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 220 2.3E-15 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_21020 6bb3a34febabcf1a7d58abecf8cef95c 229 Gene3D G3DSA:1.10.3720.10 6 221 5.0E-45 T 14-10-2018 IPR035906 MetI-like superfamily LH59_21020 6bb3a34febabcf1a7d58abecf8cef95c 229 SUPERFAMILY SSF161098 14 205 1.3E-38 T 14-10-2018 IPR035906 MetI-like superfamily LH59_21020 6bb3a34febabcf1a7d58abecf8cef95c 229 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 112 3.6E-25 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 LH59_00325 5201fb449a80915e2b60b1f33aba7c4d 256 SUPERFAMILY SSF52540 1 233 2.18E-66 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_00325 5201fb449a80915e2b60b1f33aba7c4d 256 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_00325 5201fb449a80915e2b60b1f33aba7c4d 256 Pfam PF00005 ABC transporter 23 161 6.1E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_00325 5201fb449a80915e2b60b1f33aba7c4d 256 SMART SM00382 30 211 4.8E-19 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_00325 5201fb449a80915e2b60b1f33aba7c4d 256 Gene3D G3DSA:3.40.50.300 1 242 1.8E-65 T 14-10-2018 LH59_23255 b2873728e49333874a53c373ffb61d81 416 TIGRFAM TIGR01814 kynureninase: kynureninase 9 400 1.8E-103 T 14-10-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 LH59_23255 b2873728e49333874a53c373ffb61d81 416 Pfam PF00266 Aminotransferase class-V 80 347 2.1E-12 T 14-10-2018 IPR000192 Aminotransferase class V domain LH59_23255 b2873728e49333874a53c373ffb61d81 416 PIRSF PIRSF038800 1 407 9.9E-146 T 14-10-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 LH59_23255 b2873728e49333874a53c373ffb61d81 416 SUPERFAMILY SSF53383 3 400 4.03E-86 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_23255 b2873728e49333874a53c373ffb61d81 416 Hamap MF_01970 Kynureninase [kynU]. 1 399 34.669 T 14-10-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 LH59_23255 b2873728e49333874a53c373ffb61d81 416 Gene3D G3DSA:3.90.1150.10 11 399 2.4E-159 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_23255 b2873728e49333874a53c373ffb61d81 416 Gene3D G3DSA:3.40.640.10 41 303 2.4E-159 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_10415 296d8c047916080e35f46357cca2c197 149 Gene3D G3DSA:2.40.50.140 30 137 1.5E-38 T 14-10-2018 LH59_10415 296d8c047916080e35f46357cca2c197 149 Pfam PF03100 CcmE 5 130 8.8E-45 T 14-10-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004|GO:0020037 LH59_10415 296d8c047916080e35f46357cca2c197 149 Hamap MF_01959 Cytochrome c-type biogenesis protein CcmE [ccmE]. 2 141 32.447 T 14-10-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004|GO:0020037 LH59_10415 296d8c047916080e35f46357cca2c197 149 SUPERFAMILY SSF82093 30 136 2.35E-38 T 14-10-2018 IPR036127 CcmE-like superfamily GO:0005886|GO:0017003|GO:0017004 LH59_02460 ee523321d35457165dedccaf16c61e3d 164 Gene3D G3DSA:2.60.40.420 28 164 1.1E-28 T 14-10-2018 IPR008972 Cupredoxin LH59_02460 ee523321d35457165dedccaf16c61e3d 164 SUPERFAMILY SSF49503 53 163 3.88E-30 T 14-10-2018 IPR008972 Cupredoxin LH59_02460 ee523321d35457165dedccaf16c61e3d 164 Pfam PF00127 Copper binding proteins, plastocyanin/azurin family 56 164 1.2E-10 T 14-10-2018 IPR000923 Blue (type 1) copper domain GO:0005507|GO:0009055 LH59_02460 ee523321d35457165dedccaf16c61e3d 164 ProDom PD003655 COPPER ELECTRON AZURIN METAL-BINDING PERIPLASMIC PRECURSOR SIGNAL SEQUENCING DIRECT MEMBRANE 63 162 2.0E-5 T 14-10-2018 LH59_02460 ee523321d35457165dedccaf16c61e3d 164 ProSitePatterns PS00196 Type-1 copper (blue) proteins signature. 141 157 - T 14-10-2018 IPR028871 Blue (type 1) copper protein, binding site LH59_12750 508d5078eafc35b258cee7a7682512ef 500 Gene3D G3DSA:1.10.10.60 412 498 5.6E-17 T 14-10-2018 LH59_12750 508d5078eafc35b258cee7a7682512ef 500 TIGRFAM TIGR01818 ntrC: nitrogen regulation protein NR(I) 4 390 4.2E-187 T 14-10-2018 IPR010114 DNA-binding transcriptional regulator NtrC GO:0000156|GO:0000160|GO:0003677|GO:0005524|GO:0006808 LH59_12750 508d5078eafc35b258cee7a7682512ef 500 Gene3D G3DSA:3.40.50.300 129 311 1.6E-62 T 14-10-2018 LH59_12750 508d5078eafc35b258cee7a7682512ef 500 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 354 363 - T 14-10-2018 IPR025944 Sigma-54 interaction domain, conserved site LH59_12750 508d5078eafc35b258cee7a7682512ef 500 SUPERFAMILY SSF46689 418 498 2.02E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_12750 508d5078eafc35b258cee7a7682512ef 500 Gene3D G3DSA:3.40.50.2300 1 121 6.1E-36 T 14-10-2018 LH59_12750 508d5078eafc35b258cee7a7682512ef 500 Pfam PF02954 Bacterial regulatory protein, Fis family 456 495 2.9E-11 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 LH59_12750 508d5078eafc35b258cee7a7682512ef 500 SMART SM00448 2 113 3.2E-30 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_12750 508d5078eafc35b258cee7a7682512ef 500 Gene3D G3DSA:1.10.8.60 312 391 2.4E-21 T 14-10-2018 LH59_12750 508d5078eafc35b258cee7a7682512ef 500 Pfam PF00158 Sigma-54 interaction domain 144 307 1.9E-67 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 LH59_12750 508d5078eafc35b258cee7a7682512ef 500 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 165 178 - T 14-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 LH59_12750 508d5078eafc35b258cee7a7682512ef 500 SMART SM00382 161 304 4.6E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_12750 508d5078eafc35b258cee7a7682512ef 500 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 227 242 - T 14-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 LH59_12750 508d5078eafc35b258cee7a7682512ef 500 SUPERFAMILY SSF52540 145 384 1.56E-70 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_12750 508d5078eafc35b258cee7a7682512ef 500 Pfam PF00072 Response regulator receiver domain 4 113 5.7E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_12750 508d5078eafc35b258cee7a7682512ef 500 SUPERFAMILY SSF52172 2 185 3.13E-40 T 14-10-2018 IPR011006 CheY-like superfamily LH59_12750 508d5078eafc35b258cee7a7682512ef 500 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 478 498 1.4E-9 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 LH59_12750 508d5078eafc35b258cee7a7682512ef 500 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 461 478 1.4E-9 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 LH59_15440 3a905567531626f046813ccf3d1b5de5 612 Pfam PF05947 Type VI secretion system, TssF 5 609 3.0E-210 T 14-10-2018 IPR010272 Type VI secretion system, TssF-like LH59_15440 3a905567531626f046813ccf3d1b5de5 612 PIRSF PIRSF028304 1 611 2.2E-194 T 14-10-2018 IPR010272 Type VI secretion system, TssF-like LH59_15440 3a905567531626f046813ccf3d1b5de5 612 TIGRFAM TIGR03359 VI_chp_6: type VI secretion protein, TIGR03359 family 4 611 9.6E-218 T 14-10-2018 IPR010272 Type VI secretion system, TssF-like LH59_14015 e740a882d45944fd120a506432e843b3 456 Gene3D G3DSA:1.10.287.130 157 273 6.6E-19 T 14-10-2018 LH59_14015 e740a882d45944fd120a506432e843b3 456 SMART SM00388 207 273 1.3E-8 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_14015 e740a882d45944fd120a506432e843b3 456 SUPERFAMILY SSF55874 349 450 3.41E-24 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_14015 e740a882d45944fd120a506432e843b3 456 SMART SM00387 349 454 3.8E-24 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_14015 e740a882d45944fd120a506432e843b3 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 382 396 8.5E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_14015 e740a882d45944fd120a506432e843b3 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 400 410 8.5E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_14015 e740a882d45944fd120a506432e843b3 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 438 451 8.5E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_14015 e740a882d45944fd120a506432e843b3 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 414 432 8.5E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_14015 e740a882d45944fd120a506432e843b3 456 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 354 450 1.8E-16 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_14015 e740a882d45944fd120a506432e843b3 456 SUPERFAMILY SSF47384 190 269 1.12E-12 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 LH59_14015 e740a882d45944fd120a506432e843b3 456 Pfam PF00672 HAMP domain 153 202 1.9E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_14015 e740a882d45944fd120a506432e843b3 456 SMART SM00304 153 206 5.3E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_14015 e740a882d45944fd120a506432e843b3 456 Gene3D G3DSA:3.30.565.10 340 455 4.2E-24 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_14015 e740a882d45944fd120a506432e843b3 456 Pfam PF00512 His Kinase A (phospho-acceptor) domain 210 269 4.5E-8 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_20300 cd6de2da60661f4a280b533b378bf92a 421 SUPERFAMILY SSF55021 257 335 6.65E-17 T 14-10-2018 LH59_20300 cd6de2da60661f4a280b533b378bf92a 421 Gene3D G3DSA:3.30.70.260 270 348 1.4E-54 T 14-10-2018 LH59_20300 cd6de2da60661f4a280b533b378bf92a 421 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 14-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 LH59_20300 cd6de2da60661f4a280b533b378bf92a 421 Gene3D G3DSA:3.40.1160.10 1 263 2.4E-86 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily LH59_20300 cd6de2da60661f4a280b533b378bf92a 421 PIRSF PIRSF000726 58 420 1.4E-132 T 14-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 LH59_20300 cd6de2da60661f4a280b533b378bf92a 421 PIRSF PIRSF000726 1 62 2.2E-20 T 14-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 LH59_20300 cd6de2da60661f4a280b533b378bf92a 421 Gene3D G3DSA:3.30.70.260 264 413 1.4E-54 T 14-10-2018 LH59_20300 cd6de2da60661f4a280b533b378bf92a 421 Pfam PF13840 ACT domain 346 409 1.3E-12 T 14-10-2018 IPR027795 CASTOR, ACT domain LH59_20300 cd6de2da60661f4a280b533b378bf92a 421 Pfam PF01842 ACT domain 276 333 9.5E-9 T 14-10-2018 IPR002912 ACT domain LH59_20300 cd6de2da60661f4a280b533b378bf92a 421 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 1 412 1.3E-122 T 14-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 LH59_20300 cd6de2da60661f4a280b533b378bf92a 421 PRINTS PR00474 Glutamate 5-kinase family signature 33 47 1.2E-5 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 LH59_20300 cd6de2da60661f4a280b533b378bf92a 421 PRINTS PR00474 Glutamate 5-kinase family signature 152 179 1.2E-5 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 LH59_20300 cd6de2da60661f4a280b533b378bf92a 421 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 63 412 5.7E-109 T 14-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 LH59_20300 cd6de2da60661f4a280b533b378bf92a 421 Pfam PF00696 Amino acid kinase family 3 229 3.4E-48 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 LH59_20300 cd6de2da60661f4a280b533b378bf92a 421 SUPERFAMILY SSF55021 340 414 2.55E-22 T 14-10-2018 LH59_20300 cd6de2da60661f4a280b533b378bf92a 421 SUPERFAMILY SSF53633 4 250 3.01E-73 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily LH59_06195 c441d47f5a9031d810fb4da212e8218c 227 Gene3D G3DSA:3.90.550.10 1 227 2.6E-62 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases LH59_06195 c441d47f5a9031d810fb4da212e8218c 227 SUPERFAMILY SSF53448 5 227 4.73E-50 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases LH59_06195 c441d47f5a9031d810fb4da212e8218c 227 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 4 227 40.787 T 14-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 LH59_06195 c441d47f5a9031d810fb4da212e8218c 227 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 105 112 - T 14-10-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 LH59_06195 c441d47f5a9031d810fb4da212e8218c 227 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 5 225 1.6E-56 T 14-10-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 LH59_06195 c441d47f5a9031d810fb4da212e8218c 227 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 7 225 2.0E-60 T 14-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 LH59_24355 f57b8a8f92cfe820b59b659d03ea1049 259 Pfam PF00005 ABC transporter 20 175 1.7E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_24355 f57b8a8f92cfe820b59b659d03ea1049 259 Gene3D G3DSA:3.40.50.300 2 249 2.7E-56 T 14-10-2018 LH59_24355 f57b8a8f92cfe820b59b659d03ea1049 259 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 224 244 2.1E-7 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal LH59_24355 f57b8a8f92cfe820b59b659d03ea1049 259 SUPERFAMILY SSF52540 3 245 4.18E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_24355 f57b8a8f92cfe820b59b659d03ea1049 259 SMART SM00382 28 222 3.8E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_19240 5f9deb516180b1f54c7c0d0b8013f0ea 193 Pfam PF12804 MobA-like NTP transferase domain 9 150 2.6E-22 T 14-10-2018 IPR025877 MobA-like NTP transferase LH59_19240 5f9deb516180b1f54c7c0d0b8013f0ea 193 Gene3D G3DSA:3.90.550.10 6 183 4.2E-33 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases LH59_19240 5f9deb516180b1f54c7c0d0b8013f0ea 193 SUPERFAMILY SSF53448 9 186 2.25E-22 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases LH59_19170 2e96bec557ac81c7ee2ff5f1a5a3e2a5 353 Gene3D G3DSA:3.40.50.2300 94 343 3.7E-41 T 14-10-2018 LH59_19170 2e96bec557ac81c7ee2ff5f1a5a3e2a5 353 Pfam PF00356 Bacterial regulatory proteins, lacI family 17 61 2.4E-13 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 LH59_19170 2e96bec557ac81c7ee2ff5f1a5a3e2a5 353 Gene3D G3DSA:1.10.260.40 6 68 1.2E-15 T 14-10-2018 LH59_19170 2e96bec557ac81c7ee2ff5f1a5a3e2a5 353 ProSitePatterns PS00356 LacI-type HTH domain signature. 18 36 - T 14-10-2018 LH59_19170 2e96bec557ac81c7ee2ff5f1a5a3e2a5 353 Gene3D G3DSA:3.40.50.2300 179 352 3.7E-41 T 14-10-2018 LH59_19170 2e96bec557ac81c7ee2ff5f1a5a3e2a5 353 SUPERFAMILY SSF53822 76 337 1.61E-38 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_19170 2e96bec557ac81c7ee2ff5f1a5a3e2a5 353 Pfam PF13407 Periplasmic binding protein domain 130 323 1.3E-34 T 14-10-2018 IPR025997 Periplasmic binding protein LH59_19170 2e96bec557ac81c7ee2ff5f1a5a3e2a5 353 SMART SM00354 15 85 1.6E-7 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 LH59_19170 2e96bec557ac81c7ee2ff5f1a5a3e2a5 353 SUPERFAMILY SSF47413 14 63 4.13E-12 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 LH59_07130 4db160ac59ddebe7ba579756ac3ee389 856 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 473 496 - T 14-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 LH59_07130 4db160ac59ddebe7ba579756ac3ee389 856 TIGRFAM TIGR02068 cya_phycin_syn: cyanophycin synthetase 2 852 0.0 T 14-10-2018 IPR011810 Cyanophycin synthetase GO:0005524|GO:0009059|GO:0016874 MetaCyc: PWY-7052 LH59_07130 4db160ac59ddebe7ba579756ac3ee389 856 Pfam PF02875 Mur ligase family, glutamate ligase domain 711 785 1.4E-11 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 LH59_07130 4db160ac59ddebe7ba579756ac3ee389 856 SUPERFAMILY SSF53244 711 838 9.77E-24 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 LH59_07130 4db160ac59ddebe7ba579756ac3ee389 856 Gene3D G3DSA:3.30.470.20 363 463 4.5E-12 T 14-10-2018 LH59_07130 4db160ac59ddebe7ba579756ac3ee389 856 SUPERFAMILY SSF53623 433 724 2.75E-42 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 LH59_07130 4db160ac59ddebe7ba579756ac3ee389 856 SUPERFAMILY SSF56059 204 459 1.64E-36 T 14-10-2018 LH59_07130 4db160ac59ddebe7ba579756ac3ee389 856 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 204 287 9.8E-7 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 LH59_07130 4db160ac59ddebe7ba579756ac3ee389 856 Gene3D G3DSA:3.90.190.20 712 854 2.5E-18 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 LH59_07130 4db160ac59ddebe7ba579756ac3ee389 856 Pfam PF08245 Mur ligase middle domain 475 686 7.9E-21 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 LH59_07130 4db160ac59ddebe7ba579756ac3ee389 856 SMART SM01209 203 336 0.0085 T 14-10-2018 LH59_07130 4db160ac59ddebe7ba579756ac3ee389 856 Gene3D G3DSA:3.40.1190.10 468 705 2.1E-38 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 LH59_07130 4db160ac59ddebe7ba579756ac3ee389 856 Gene3D G3DSA:3.30.1490.20 204 286 3.0E-19 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 LH59_01085 8bab51a18df0d1797790bebaa2ee3398 1579 Gene3D G3DSA:3.60.20.10 41 475 1.5E-183 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal LH59_01085 8bab51a18df0d1797790bebaa2ee3398 1579 Pfam PF01645 Conserved region in glutamate synthase 834 1233 1.1E-156 T 14-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 LH59_01085 8bab51a18df0d1797790bebaa2ee3398 1579 Pfam PF01493 GXGXG motif 1311 1496 1.3E-77 T 14-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 LH59_01085 8bab51a18df0d1797790bebaa2ee3398 1579 Pfam PF04898 Glutamate synthase central domain 494 773 1.3E-109 T 14-10-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 LH59_01085 8bab51a18df0d1797790bebaa2ee3398 1579 Gene3D G3DSA:2.160.20.60 1285 1576 1.1E-105 T 14-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 LH59_01085 8bab51a18df0d1797790bebaa2ee3398 1579 Gene3D G3DSA:3.20.20.70 478 817 1.5E-121 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_01085 8bab51a18df0d1797790bebaa2ee3398 1579 SUPERFAMILY SSF56235 41 467 3.17E-154 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal LH59_01085 8bab51a18df0d1797790bebaa2ee3398 1579 Pfam PF00310 Glutamine amidotransferases class-II 41 464 3.3E-185 T 14-10-2018 IPR017932 Glutamine amidotransferase type 2 domain LH59_01085 8bab51a18df0d1797790bebaa2ee3398 1579 SUPERFAMILY SSF69336 1280 1568 2.09E-90 T 14-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 LH59_01085 8bab51a18df0d1797790bebaa2ee3398 1579 SUPERFAMILY SSF51395 485 1267 2.81E-263 T 14-10-2018 LH59_01085 8bab51a18df0d1797790bebaa2ee3398 1579 Gene3D G3DSA:3.20.20.70 818 1284 1.0E-206 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_01565 abc90f059b8b2125d700403d7e72dba9 486 Gene3D G3DSA:3.40.309.10 256 453 1.8E-162 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 LH59_01565 abc90f059b8b2125d700403d7e72dba9 486 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 252 259 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 LH59_01565 abc90f059b8b2125d700403d7e72dba9 486 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 280 291 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 LH59_01565 abc90f059b8b2125d700403d7e72dba9 486 Gene3D G3DSA:3.40.605.10 24 481 1.8E-162 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 LH59_01565 abc90f059b8b2125d700403d7e72dba9 486 Pfam PF00171 Aldehyde dehydrogenase family 17 482 5.9E-164 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 LH59_01565 abc90f059b8b2125d700403d7e72dba9 486 SUPERFAMILY SSF53720 8 484 6.15E-156 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 LH59_16320 39cbb8164d078a558b47de193eae32b2 328 Gene3D G3DSA:3.40.190.10 130 253 3.3E-108 T 14-10-2018 LH59_16320 39cbb8164d078a558b47de193eae32b2 328 Gene3D G3DSA:3.40.190.150 34 318 3.3E-108 T 14-10-2018 LH59_16320 39cbb8164d078a558b47de193eae32b2 328 SUPERFAMILY SSF53850 115 294 4.93E-14 T 14-10-2018 LH59_16320 39cbb8164d078a558b47de193eae32b2 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 54 324 7.8E-81 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_16320 39cbb8164d078a558b47de193eae32b2 328 PIRSF PIRSF017082 1 327 1.1E-83 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_13950 0824f11bb5b377db08b56785f5da3871 288 SUPERFAMILY SSF52540 10 245 6.72E-69 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_13950 0824f11bb5b377db08b56785f5da3871 288 SMART SM00382 40 233 1.1E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_13950 0824f11bb5b377db08b56785f5da3871 288 Gene3D G3DSA:3.40.50.300 9 234 3.6E-62 T 14-10-2018 LH59_13950 0824f11bb5b377db08b56785f5da3871 288 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_13950 0824f11bb5b377db08b56785f5da3871 288 Pfam PF00005 ABC transporter 33 170 4.8E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_02335 67ed8bc9e99f50ca7da248d5b21f5b39 75 SUPERFAMILY SSF46894 4 71 2.38E-18 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LH59_02335 67ed8bc9e99f50ca7da248d5b21f5b39 75 Pfam PF00196 Bacterial regulatory proteins, luxR family 9 63 1.3E-18 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_02335 67ed8bc9e99f50ca7da248d5b21f5b39 75 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 40 52 2.7E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_02335 67ed8bc9e99f50ca7da248d5b21f5b39 75 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 10 24 2.7E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_02335 67ed8bc9e99f50ca7da248d5b21f5b39 75 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 24 40 2.7E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_02335 67ed8bc9e99f50ca7da248d5b21f5b39 75 Gene3D G3DSA:1.10.10.10 4 71 9.4E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_02335 67ed8bc9e99f50ca7da248d5b21f5b39 75 SMART SM00421 7 64 8.3E-17 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_23860 a7451c75c18e410b10e3981595371cce 119 PIRSF PIRSF037511 1 119 1.1E-33 T 14-10-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 LH59_23860 a7451c75c18e410b10e3981595371cce 119 SUPERFAMILY SSF55159 7 115 2.62E-26 T 14-10-2018 IPR036877 SUI1 domain superfamily GO:0003743|GO:0006413 LH59_23860 a7451c75c18e410b10e3981595371cce 119 Pfam PF01253 Translation initiation factor SUI1 45 110 1.8E-14 T 14-10-2018 IPR001950 SUI1 domain GO:0003743|GO:0006413 LH59_23860 a7451c75c18e410b10e3981595371cce 119 Gene3D G3DSA:3.30.780.10 41 119 1.2E-28 T 14-10-2018 LH59_23825 c0cc352ee326f066d1c69faed752c198 850 SUPERFAMILY SSF56014 638 813 4.71E-49 T 14-10-2018 LH59_23825 c0cc352ee326f066d1c69faed752c198 850 SUPERFAMILY SSF51905 155 314 1.22E-23 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_23825 c0cc352ee326f066d1c69faed752c198 850 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 13 805 0.0 T 14-10-2018 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 LH59_23825 c0cc352ee326f066d1c69faed752c198 850 PRINTS PR00397 Sirohaem Fe-binding site signature 641 659 6.5E-7 T 14-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 LH59_23825 c0cc352ee326f066d1c69faed752c198 850 PRINTS PR00397 Sirohaem Fe-binding site signature 684 702 6.5E-7 T 14-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 LH59_23825 c0cc352ee326f066d1c69faed752c198 850 Gene3D G3DSA:3.50.50.60 116 251 1.8E-81 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_23825 c0cc352ee326f066d1c69faed752c198 850 SUPERFAMILY SSF51905 6 195 1.23E-40 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_23825 c0cc352ee326f066d1c69faed752c198 850 Pfam PF04324 BFD-like [2Fe-2S] binding domain 427 475 7.5E-7 T 14-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain LH59_23825 c0cc352ee326f066d1c69faed752c198 850 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 637 757 1.5E-18 T 14-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 LH59_23825 c0cc352ee326f066d1c69faed752c198 850 Gene3D G3DSA:3.50.50.60 14 288 1.8E-81 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_23825 c0cc352ee326f066d1c69faed752c198 850 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 108 126 1.7E-14 T 14-10-2018 LH59_23825 c0cc352ee326f066d1c69faed752c198 850 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 288 1.7E-14 T 14-10-2018 LH59_23825 c0cc352ee326f066d1c69faed752c198 850 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 153 171 1.7E-14 T 14-10-2018 LH59_23825 c0cc352ee326f066d1c69faed752c198 850 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 13 32 1.7E-14 T 14-10-2018 LH59_23825 c0cc352ee326f066d1c69faed752c198 850 Gene3D G3DSA:3.30.413.10 635 783 1.4E-32 T 14-10-2018 LH59_23825 c0cc352ee326f066d1c69faed752c198 850 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 12 34 1.9E-11 T 14-10-2018 LH59_23825 c0cc352ee326f066d1c69faed752c198 850 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 153 178 1.9E-11 T 14-10-2018 LH59_23825 c0cc352ee326f066d1c69faed752c198 850 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 240 254 1.9E-11 T 14-10-2018 LH59_23825 c0cc352ee326f066d1c69faed752c198 850 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 281 288 1.9E-11 T 14-10-2018 LH59_23825 c0cc352ee326f066d1c69faed752c198 850 SUPERFAMILY SSF55124 518 646 2.78E-26 T 14-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 LH59_23825 c0cc352ee326f066d1c69faed752c198 850 PIRSF PIRSF037149 5 840 0.0 T 14-10-2018 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 LH59_23825 c0cc352ee326f066d1c69faed752c198 850 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 13 292 9.3E-47 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LH59_23825 c0cc352ee326f066d1c69faed752c198 850 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 684 700 - T 14-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 LH59_23825 c0cc352ee326f066d1c69faed752c198 850 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 565 627 2.5E-11 T 14-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 LH59_23825 c0cc352ee326f066d1c69faed752c198 850 Gene3D G3DSA:1.10.10.1100 427 481 2.0E-8 T 14-10-2018 LH59_15330 4ab3e88ccf557d61005d7dceabc008ab 177 ProSitePatterns PS01117 MarR-type HTH domain signature. 90 124 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site LH59_15330 4ab3e88ccf557d61005d7dceabc008ab 177 PRINTS PR00598 Bacterial regulatory protein MarR family signature 92 107 1.1E-13 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_15330 4ab3e88ccf557d61005d7dceabc008ab 177 PRINTS PR00598 Bacterial regulatory protein MarR family signature 111 127 1.1E-13 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_15330 4ab3e88ccf557d61005d7dceabc008ab 177 PRINTS PR00598 Bacterial regulatory protein MarR family signature 141 161 1.1E-13 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_15330 4ab3e88ccf557d61005d7dceabc008ab 177 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 91 1.1E-13 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_15330 4ab3e88ccf557d61005d7dceabc008ab 177 SMART SM00347 50 151 3.8E-29 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_15330 4ab3e88ccf557d61005d7dceabc008ab 177 Pfam PF01047 MarR family 57 116 7.2E-14 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_15330 4ab3e88ccf557d61005d7dceabc008ab 177 Gene3D G3DSA:1.10.10.10 9 166 6.8E-36 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_15330 4ab3e88ccf557d61005d7dceabc008ab 177 SUPERFAMILY SSF46785 31 163 1.02E-33 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_15005 cfd84a910f9ad9643b55f659973d7bea 126 Pfam PF11720 Peptidase inhibitor I78 family 62 126 8.2E-23 T 14-10-2018 IPR021719 Proteinase inhibitor I78 LH59_15005 cfd84a910f9ad9643b55f659973d7bea 126 Gene3D G3DSA:3.30.10.10 58 125 4.9E-17 T 14-10-2018 LH59_07625 194148c37cf85bd4633d049460bca111 167 Pfam PF02576 RimP N-terminal domain 9 74 4.9E-15 T 14-10-2018 IPR028989 Ribosome maturation factor RimP, N-terminal LH59_07625 194148c37cf85bd4633d049460bca111 167 Gene3D G3DSA:3.30.300.70 2 71 4.4E-9 T 14-10-2018 IPR035956 RimP, N-terminal domain superfamily LH59_07625 194148c37cf85bd4633d049460bca111 167 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 2 160 20.913 T 14-10-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 LH59_07625 194148c37cf85bd4633d049460bca111 167 SUPERFAMILY SSF74942 75 157 2.48E-9 T 14-10-2018 IPR036847 Ribosome maturation factor RimP, C-terminal domain superfamily LH59_07625 194148c37cf85bd4633d049460bca111 167 Pfam PF17384 RimP C-terminal SH3 domain 77 158 2.1E-9 T 14-10-2018 IPR028998 Ribosome maturation factor RimP, C-terminal LH59_07625 194148c37cf85bd4633d049460bca111 167 SUPERFAMILY SSF75420 3 74 2.35E-14 T 14-10-2018 IPR035956 RimP, N-terminal domain superfamily LH59_09440 9d2f259a361d74d9c5bdcfeb8a40d52d 654 SMART SM00257 167 222 0.0026 T 14-10-2018 IPR018392 LysM domain LH59_09440 9d2f259a361d74d9c5bdcfeb8a40d52d 654 Pfam PF01476 LysM domain 170 222 5.4E-6 T 14-10-2018 IPR018392 LysM domain LH59_09440 9d2f259a361d74d9c5bdcfeb8a40d52d 654 Gene3D G3DSA:3.10.350.10 156 234 2.7E-7 T 14-10-2018 IPR036779 LysM domain superfamily LH59_09440 9d2f259a361d74d9c5bdcfeb8a40d52d 654 TIGRFAM TIGR03505 FimV_core: FimV N-terminal domain 174 245 3.3E-23 T 14-10-2018 IPR020012 Motility protein FimV, N-terminal LH59_09440 9d2f259a361d74d9c5bdcfeb8a40d52d 654 Pfam PF01391 Collagen triple helix repeat (20 copies) 487 545 1.8E-8 T 14-10-2018 IPR008160 Collagen triple helix repeat LH59_09440 9d2f259a361d74d9c5bdcfeb8a40d52d 654 Pfam PF01391 Collagen triple helix repeat (20 copies) 436 494 3.6E-8 T 14-10-2018 IPR008160 Collagen triple helix repeat LH59_20235 6c04d2d10742a141d0b98061796f12e9 1078 SUPERFAMILY SSF52172 850 969 1.25E-35 T 14-10-2018 IPR011006 CheY-like superfamily LH59_20235 6c04d2d10742a141d0b98061796f12e9 1078 SUPERFAMILY SSF55874 550 720 4.71E-38 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_20235 6c04d2d10742a141d0b98061796f12e9 1078 Gene3D G3DSA:3.40.50.2300 834 966 2.8E-35 T 14-10-2018 LH59_20235 6c04d2d10742a141d0b98061796f12e9 1078 PRINTS PR00344 Bacterial sensor protein C-terminal signature 683 701 4.8E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_20235 6c04d2d10742a141d0b98061796f12e9 1078 PRINTS PR00344 Bacterial sensor protein C-terminal signature 707 720 4.8E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_20235 6c04d2d10742a141d0b98061796f12e9 1078 PRINTS PR00344 Bacterial sensor protein C-terminal signature 667 677 4.8E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_20235 6c04d2d10742a141d0b98061796f12e9 1078 PRINTS PR00344 Bacterial sensor protein C-terminal signature 649 663 4.8E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_20235 6c04d2d10742a141d0b98061796f12e9 1078 Gene3D G3DSA:1.10.287.130 477 559 1.5E-24 T 14-10-2018 LH59_20235 6c04d2d10742a141d0b98061796f12e9 1078 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 608 722 1.4E-23 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_20235 6c04d2d10742a141d0b98061796f12e9 1078 SUPERFAMILY SSF47384 480 562 1.1E-20 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 LH59_20235 6c04d2d10742a141d0b98061796f12e9 1078 Pfam PF01627 Hpt domain 994 1067 5.1E-7 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 LH59_20235 6c04d2d10742a141d0b98061796f12e9 1078 Gene3D G3DSA:1.20.120.160 983 1075 6.5E-10 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 LH59_20235 6c04d2d10742a141d0b98061796f12e9 1078 SMART SM00388 496 561 1.2E-22 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_20235 6c04d2d10742a141d0b98061796f12e9 1078 Pfam PF00072 Response regulator receiver domain 853 960 1.2E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_20235 6c04d2d10742a141d0b98061796f12e9 1078 Pfam PF00512 His Kinase A (phospho-acceptor) domain 496 561 4.4E-17 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_20235 6c04d2d10742a141d0b98061796f12e9 1078 SUPERFAMILY SSF55785 368 474 1.54E-8 T 14-10-2018 IPR035965 PAS domain superfamily LH59_20235 6c04d2d10742a141d0b98061796f12e9 1078 Gene3D G3DSA:3.30.450.20 367 476 6.7E-6 T 14-10-2018 LH59_20235 6c04d2d10742a141d0b98061796f12e9 1078 SUPERFAMILY SSF47226 945 1059 7.2E-12 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 LH59_20235 6c04d2d10742a141d0b98061796f12e9 1078 SMART SM00448 851 962 6.4E-31 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_20235 6c04d2d10742a141d0b98061796f12e9 1078 Gene3D G3DSA:3.30.565.10 560 725 1.0E-40 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_20235 6c04d2d10742a141d0b98061796f12e9 1078 SMART SM00387 608 723 6.8E-30 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_12770 d7400a11f6b6a09814a80caab35def5e 325 SUPERFAMILY SSF53850 121 285 4.75E-10 T 14-10-2018 LH59_12770 d7400a11f6b6a09814a80caab35def5e 325 PIRSF PIRSF017082 1 325 2.3E-75 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_12770 d7400a11f6b6a09814a80caab35def5e 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 321 2.8E-85 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_12770 d7400a11f6b6a09814a80caab35def5e 325 Gene3D G3DSA:3.40.190.150 30 315 1.1E-107 T 14-10-2018 LH59_12770 d7400a11f6b6a09814a80caab35def5e 325 Gene3D G3DSA:3.40.190.10 128 250 1.1E-107 T 14-10-2018 LH59_10825 cea22b72c1ae164079d84d87fae76cca 266 Pfam PF05013 N-formylglutamate amidohydrolase 12 230 8.1E-71 T 14-10-2018 IPR007709 N-formylglutamate amidohydrolase LH59_10825 cea22b72c1ae164079d84d87fae76cca 266 Gene3D G3DSA:3.40.630.40 2 257 7.3E-79 T 14-10-2018 LH59_10825 cea22b72c1ae164079d84d87fae76cca 266 SUPERFAMILY SSF53187 4 258 2.1E-79 T 14-10-2018 LH59_10825 cea22b72c1ae164079d84d87fae76cca 266 TIGRFAM TIGR02017 hutG_amidohyd: N-formylglutamate deformylase 4 259 3.4E-101 T 14-10-2018 IPR010247 N-formylglutamate deformylase LH59_17255 9615af59d2bc183362b490ea0d701e47 187 Gene3D G3DSA:1.25.40.10 88 187 4.0E-35 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_17255 9615af59d2bc183362b490ea0d701e47 187 Pfam PF06041 Bacterial protein of unknown function (DUF924) 17 184 5.0E-55 T 14-10-2018 IPR010323 Protein of unknown function DUF924 LH59_17255 9615af59d2bc183362b490ea0d701e47 187 Gene3D G3DSA:1.20.58.320 9 87 2.9E-28 T 14-10-2018 LH59_17255 9615af59d2bc183362b490ea0d701e47 187 SUPERFAMILY SSF48452 11 183 3.64E-63 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_00930 3c2dbb118b702d8884b5e5bf37dc98c0 116 Gene3D G3DSA:1.10.287.1080 7 103 5.7E-28 T 14-10-2018 LH59_00930 3c2dbb118b702d8884b5e5bf37dc98c0 116 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 20 101 2.5E-14 T 14-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 LH59_00930 3c2dbb118b702d8884b5e5bf37dc98c0 116 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 12 98 3.4E-27 T 14-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 LH59_00930 3c2dbb118b702d8884b5e5bf37dc98c0 116 SUPERFAMILY SSF101386 14 102 3.18E-22 T 14-10-2018 LH59_00930 3c2dbb118b702d8884b5e5bf37dc98c0 116 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 9 98 20.658 T 14-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 LH59_20145 4ae02762c58ba00fefac3f22a31ebc3b 387 Gene3D G3DSA:3.40.50.10540 7 336 6.5E-132 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily LH59_20145 4ae02762c58ba00fefac3f22a31ebc3b 387 Pfam PF02515 CoA-transferase family III 7 373 4.2E-129 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 LH59_20145 4ae02762c58ba00fefac3f22a31ebc3b 387 SUPERFAMILY SSF89796 6 380 6.8E-135 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily LH59_20145 4ae02762c58ba00fefac3f22a31ebc3b 387 Gene3D G3DSA:3.30.1540.10 227 318 6.5E-132 T 14-10-2018 LH59_09070 20f1a8ae8c57ba425922f16f06574f58 348 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 132 142 4.6E-7 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 LH59_09070 20f1a8ae8c57ba425922f16f06574f58 348 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 148 155 4.6E-7 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 LH59_09070 20f1a8ae8c57ba425922f16f06574f58 348 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 304 312 4.6E-7 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 LH59_09070 20f1a8ae8c57ba425922f16f06574f58 348 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 212 231 4.6E-7 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 LH59_09070 20f1a8ae8c57ba425922f16f06574f58 348 SUPERFAMILY SSF63380 103 203 2.69E-20 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel LH59_09070 20f1a8ae8c57ba425922f16f06574f58 348 Gene3D G3DSA:2.40.30.10 103 203 1.4E-21 T 14-10-2018 LH59_09070 20f1a8ae8c57ba425922f16f06574f58 348 Gene3D G3DSA:3.10.20.30 1 102 4.7E-28 T 14-10-2018 IPR012675 Beta-grasp domain superfamily LH59_09070 20f1a8ae8c57ba425922f16f06574f58 348 SUPERFAMILY SSF52343 204 338 1.3E-39 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain LH59_09070 20f1a8ae8c57ba425922f16f06574f58 348 Gene3D G3DSA:3.40.50.80 204 339 2.2E-33 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain LH59_09070 20f1a8ae8c57ba425922f16f06574f58 348 SUPERFAMILY SSF54292 1 90 1.15E-28 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 LH59_09070 20f1a8ae8c57ba425922f16f06574f58 348 Pfam PF00175 Oxidoreductase NAD-binding domain 213 318 1.1E-21 T 14-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 LH59_09070 20f1a8ae8c57ba425922f16f06574f58 348 PRINTS PR00410 Phenol hydroxylase reductase family signature 148 155 3.2E-23 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 LH59_09070 20f1a8ae8c57ba425922f16f06574f58 348 PRINTS PR00410 Phenol hydroxylase reductase family signature 196 205 3.2E-23 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 LH59_09070 20f1a8ae8c57ba425922f16f06574f58 348 PRINTS PR00410 Phenol hydroxylase reductase family signature 237 246 3.2E-23 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 LH59_09070 20f1a8ae8c57ba425922f16f06574f58 348 PRINTS PR00410 Phenol hydroxylase reductase family signature 212 231 3.2E-23 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 LH59_09070 20f1a8ae8c57ba425922f16f06574f58 348 PRINTS PR00410 Phenol hydroxylase reductase family signature 304 312 3.2E-23 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 LH59_09070 20f1a8ae8c57ba425922f16f06574f58 348 PRINTS PR00410 Phenol hydroxylase reductase family signature 132 144 3.2E-23 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 LH59_09070 20f1a8ae8c57ba425922f16f06574f58 348 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 6 81 7.8E-16 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 LH59_09070 20f1a8ae8c57ba425922f16f06574f58 348 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 37 45 - T 14-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 LH59_09070 20f1a8ae8c57ba425922f16f06574f58 348 Pfam PF00970 Oxidoreductase FAD-binding domain 106 201 3.6E-12 T 14-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 LH59_00065 d4aa79c8109fce8b39aba8d2004420b4 250 Gene3D G3DSA:1.10.3720.10 15 238 7.1E-49 T 14-10-2018 IPR035906 MetI-like superfamily LH59_00065 d4aa79c8109fce8b39aba8d2004420b4 250 SUPERFAMILY SSF161098 24 222 2.49E-39 T 14-10-2018 IPR035906 MetI-like superfamily LH59_00065 d4aa79c8109fce8b39aba8d2004420b4 250 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 23 131 1.2E-17 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 LH59_00065 d4aa79c8109fce8b39aba8d2004420b4 250 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 46 236 7.1E-20 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_15325 446142be263cbd15c6b1e87d3f24b410 256 Gene3D G3DSA:1.25.40.290 115 256 1.4E-28 T 14-10-2018 LH59_15325 446142be263cbd15c6b1e87d3f24b410 256 SUPERFAMILY SSF48371 64 254 1.01E-34 T 14-10-2018 IPR016024 Armadillo-type fold LH59_10645 989a94962b6a93b57250f1466a8c3bcd 242 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 191 232 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 LH59_10645 989a94962b6a93b57250f1466a8c3bcd 242 Pfam PF12833 Helix-turn-helix domain 162 237 1.2E-18 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_10645 989a94962b6a93b57250f1466a8c3bcd 242 Gene3D G3DSA:1.10.10.60 137 240 3.9E-19 T 14-10-2018 LH59_10645 989a94962b6a93b57250f1466a8c3bcd 242 Gene3D G3DSA:2.60.120.10 1 79 1.5E-7 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_10645 989a94962b6a93b57250f1466a8c3bcd 242 SMART SM00342 154 236 7.2E-19 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_10645 989a94962b6a93b57250f1466a8c3bcd 242 SUPERFAMILY SSF46689 191 238 8.51E-8 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_10645 989a94962b6a93b57250f1466a8c3bcd 242 SUPERFAMILY SSF51182 6 160 6.23E-13 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_10645 989a94962b6a93b57250f1466a8c3bcd 242 Pfam PF02311 AraC-like ligand binding domain 7 127 1.1E-6 T 14-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 LH59_13835 f057a40a97a5aead7681712b8143e57b 308 Pfam PF04773 FecR protein 101 193 1.5E-21 T 14-10-2018 IPR006860 FecR protein LH59_13835 f057a40a97a5aead7681712b8143e57b 308 PIRSF PIRSF018266 1 308 5.1E-82 T 14-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component LH59_13835 f057a40a97a5aead7681712b8143e57b 308 Gene3D G3DSA:2.60.120.1440 95 224 1.1E-26 T 14-10-2018 LH59_13835 f057a40a97a5aead7681712b8143e57b 308 Pfam PF16220 Domain of unknown function (DUF4880) 4 44 7.1E-9 T 14-10-2018 IPR032623 FecR, N-terminal LH59_04035 1411e918110eefcdd956350a7ef1f148 510 Pfam PF02875 Mur ligase family, glutamate ligase domain 365 435 1.9E-5 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 LH59_04035 1411e918110eefcdd956350a7ef1f148 510 SUPERFAMILY SSF53623 129 361 5.23E-46 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 LH59_04035 1411e918110eefcdd956350a7ef1f148 510 SUPERFAMILY SSF53244 363 502 1.19E-43 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 LH59_04035 1411e918110eefcdd956350a7ef1f148 510 SUPERFAMILY SSF51984 14 111 1.14E-12 T 14-10-2018 LH59_04035 1411e918110eefcdd956350a7ef1f148 510 Pfam PF08245 Mur ligase middle domain 136 258 5.0E-25 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 LH59_04035 1411e918110eefcdd956350a7ef1f148 510 Gene3D G3DSA:3.40.1190.10 111 363 3.8E-50 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 LH59_04035 1411e918110eefcdd956350a7ef1f148 510 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 14 499 6.6E-109 T 14-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 LH59_04035 1411e918110eefcdd956350a7ef1f148 510 Gene3D G3DSA:3.90.190.20 369 501 5.7E-44 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 LH59_04035 1411e918110eefcdd956350a7ef1f148 510 Gene3D G3DSA:3.40.50.720 11 110 1.2E-18 T 14-10-2018 LH59_04035 1411e918110eefcdd956350a7ef1f148 510 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 12 502 32.146 T 14-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 LH59_24850 751cd0dd141cc719b944d295a00fc5c1 753 Gene3D G3DSA:3.40.640.10 151 456 1.4E-95 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_24850 751cd0dd141cc719b944d295a00fc5c1 753 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 611 735 1.6E-46 T 14-10-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 LH59_24850 751cd0dd141cc719b944d295a00fc5c1 753 PIRSF PIRSF009393 1 753 5.7E-277 T 14-10-2018 IPR011193 Ornithine/lysine/arginine decarboxylase GO:0005737|GO:0006520|GO:0016831 LH59_24850 751cd0dd141cc719b944d295a00fc5c1 753 SUPERFAMILY SSF55904 606 749 1.11E-44 T 14-10-2018 IPR036633 Orn/Lys/Arg decarboxylase, C-terminal domain superfamily GO:0003824 LH59_24850 751cd0dd141cc719b944d295a00fc5c1 753 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 392 406 - T 14-10-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 LH59_24850 751cd0dd141cc719b944d295a00fc5c1 753 Gene3D G3DSA:3.90.100.10 631 751 2.4E-38 T 14-10-2018 LH59_24850 751cd0dd141cc719b944d295a00fc5c1 753 Pfam PF03709 Orn/Lys/Arg decarboxylase, N-terminal domain 20 145 3.5E-38 T 14-10-2018 IPR005308 Orn/Lys/Arg decarboxylase, N-terminal GO:0016831 LH59_24850 751cd0dd141cc719b944d295a00fc5c1 753 SUPERFAMILY SSF53383 151 604 4.03E-116 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_24850 751cd0dd141cc719b944d295a00fc5c1 753 Gene3D G3DSA:3.40.50.2300 5 149 2.3E-19 T 14-10-2018 LH59_24850 751cd0dd141cc719b944d295a00fc5c1 753 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 151 584 1.1E-152 T 14-10-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 LH59_24850 751cd0dd141cc719b944d295a00fc5c1 753 Gene3D G3DSA:3.90.1150.10 459 630 8.1E-70 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_23060 5e2b3a5cd40a77eabe6f1f5b06f77f9d 170 Pfam PF04542 Sigma-70 region 2 12 75 1.1E-15 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 LH59_23060 5e2b3a5cd40a77eabe6f1f5b06f77f9d 170 Gene3D G3DSA:1.10.10.10 96 160 2.1E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_23060 5e2b3a5cd40a77eabe6f1f5b06f77f9d 170 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 8 153 3.1E-25 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 LH59_23060 5e2b3a5cd40a77eabe6f1f5b06f77f9d 170 SUPERFAMILY SSF88946 7 80 2.39E-17 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 LH59_23060 5e2b3a5cd40a77eabe6f1f5b06f77f9d 170 SUPERFAMILY SSF88659 96 157 8.94E-18 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like LH59_23060 5e2b3a5cd40a77eabe6f1f5b06f77f9d 170 Pfam PF08281 Sigma-70, region 4 102 153 5.0E-19 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LH59_23060 5e2b3a5cd40a77eabe6f1f5b06f77f9d 170 Gene3D G3DSA:1.10.1740.10 2 67 2.2E-23 T 14-10-2018 LH59_11160 09958f7ccab5e4056956270f44f1e561 178 SUPERFAMILY SSF52980 5 177 1.85E-74 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 LH59_11160 09958f7ccab5e4056956270f44f1e561 178 SMART SM01322 1 176 1.3E-122 T 14-10-2018 IPR009822 YaeQ LH59_11160 09958f7ccab5e4056956270f44f1e561 178 Pfam PF07152 YaeQ protein 1 173 4.6E-79 T 14-10-2018 IPR009822 YaeQ LH59_11160 09958f7ccab5e4056956270f44f1e561 178 Gene3D G3DSA:3.10.640.10 1 178 3.6E-81 T 14-10-2018 IPR038590 YaeQ superfamily LH59_11160 09958f7ccab5e4056956270f44f1e561 178 PIRSF PIRSF011484 1 178 5.9E-72 T 14-10-2018 IPR009822 YaeQ LH59_09680 b6a931d79b2308c3d84a7b0aab0fa364 340 Pfam PF01409 tRNA synthetases class II core domain (F) 93 338 2.4E-92 T 14-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 LH59_09680 b6a931d79b2308c3d84a7b0aab0fa364 340 SUPERFAMILY SSF46589 16 100 1.05E-19 T 14-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 LH59_09680 b6a931d79b2308c3d84a7b0aab0fa364 340 Gene3D G3DSA:3.30.930.10 8 340 2.4E-112 T 14-10-2018 LH59_09680 b6a931d79b2308c3d84a7b0aab0fa364 340 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 21 88 2.6E-21 T 14-10-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 LH59_09680 b6a931d79b2308c3d84a7b0aab0fa364 340 SUPERFAMILY SSF55681 93 339 5.56E-76 T 14-10-2018 LH59_09680 b6a931d79b2308c3d84a7b0aab0fa364 340 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 9 338 45.695 T 14-10-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 LH59_09680 b6a931d79b2308c3d84a7b0aab0fa364 340 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 40 339 2.6E-96 T 14-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 LH59_16495 a00225fc76c7d6dc231bce7c87791b1a 299 Gene3D G3DSA:3.40.190.10 162 264 1.2E-65 T 14-10-2018 LH59_16495 a00225fc76c7d6dc231bce7c87791b1a 299 Gene3D G3DSA:1.10.10.10 3 90 1.1E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_16495 a00225fc76c7d6dc231bce7c87791b1a 299 Gene3D G3DSA:3.40.190.10 91 291 1.2E-65 T 14-10-2018 LH59_16495 a00225fc76c7d6dc231bce7c87791b1a 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 63 4.8E-16 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_16495 a00225fc76c7d6dc231bce7c87791b1a 299 Pfam PF03466 LysR substrate binding domain 88 293 6.1E-49 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_16495 a00225fc76c7d6dc231bce7c87791b1a 299 SUPERFAMILY SSF53850 89 293 7.91E-48 T 14-10-2018 LH59_16495 a00225fc76c7d6dc231bce7c87791b1a 299 SUPERFAMILY SSF46785 5 85 7.48E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_06265 813e922dcf35840ff7cfcf464767dc25 89 Gene3D G3DSA:3.30.300.90 2 89 9.8E-24 T 14-10-2018 LH59_06265 813e922dcf35840ff7cfcf464767dc25 89 PIRSF PIRSF003113 1 89 1.4E-21 T 14-10-2018 IPR002634 BolA protein LH59_06265 813e922dcf35840ff7cfcf464767dc25 89 Pfam PF01722 BolA-like protein 17 89 1.5E-24 T 14-10-2018 IPR002634 BolA protein LH59_06265 813e922dcf35840ff7cfcf464767dc25 89 SUPERFAMILY SSF82657 7 88 3.4E-20 T 14-10-2018 IPR036065 BolA-like superfamily LH59_10145 2acb5b85441da1b7dc51a20faab5a0f5 242 SUPERFAMILY SSF53681 122 232 4.25E-28 T 14-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 LH59_10145 2acb5b85441da1b7dc51a20faab5a0f5 242 SUPERFAMILY SSF53681 8 120 3.07E-17 T 14-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 LH59_10145 2acb5b85441da1b7dc51a20faab5a0f5 242 TIGRFAM TIGR00035 asp_race: aspartate racemase 16 233 3.2E-33 T 14-10-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 LH59_10145 2acb5b85441da1b7dc51a20faab5a0f5 242 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 196 206 - T 14-10-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 LH59_10145 2acb5b85441da1b7dc51a20faab5a0f5 242 Gene3D G3DSA:3.40.50.1860 9 227 1.5E-58 T 14-10-2018 LH59_10145 2acb5b85441da1b7dc51a20faab5a0f5 242 Gene3D G3DSA:3.40.50.1860 108 218 1.5E-58 T 14-10-2018 LH59_10145 2acb5b85441da1b7dc51a20faab5a0f5 242 Pfam PF01177 Asp/Glu/Hydantoin racemase 9 227 3.6E-41 T 14-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 LH59_14450 26788d9a5979303b65ef437e55832660 185 SUPERFAMILY SSF69118 1 181 6.81E-46 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 LH59_14450 26788d9a5979303b65ef437e55832660 185 Pfam PF02627 Carboxymuconolactone decarboxylase family 43 119 1.0E-8 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 LH59_14450 26788d9a5979303b65ef437e55832660 185 Gene3D G3DSA:1.20.1290.10 13 182 1.3E-40 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 LH59_22450 3ad528944be9f19098086124a91e4557 326 Gene3D G3DSA:3.40.190.10 112 225 3.2E-88 T 14-10-2018 LH59_22450 3ad528944be9f19098086124a91e4557 326 TIGRFAM TIGR01098 3A0109s03R: phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein 6 250 9.6E-78 T 14-10-2018 IPR005770 Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein GO:0043190|GO:0055085 LH59_22450 3ad528944be9f19098086124a91e4557 326 Gene3D G3DSA:3.40.190.10 28 254 3.2E-88 T 14-10-2018 LH59_22450 3ad528944be9f19098086124a91e4557 326 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 29 277 5.9E-63 T 14-10-2018 LH59_22450 3ad528944be9f19098086124a91e4557 326 Gene3D G3DSA:1.20.58.90 276 326 4.6E-13 T 14-10-2018 LH59_22450 3ad528944be9f19098086124a91e4557 326 SUPERFAMILY SSF53850 48 241 1.47E-39 T 14-10-2018 LH59_22450 3ad528944be9f19098086124a91e4557 326 TIGRFAM TIGR03431 PhnD: phosphonate ABC transporter, periplasmic phosphonate binding protein 1 290 4.9E-109 T 14-10-2018 IPR017797 Phosphonate ABC transporter, substrate-binding protein GO:0015716|GO:0043190 LH59_23920 152bc54eacecc3d14c8f8a17414838ac 420 Pfam PF07690 Major Facilitator Superfamily 31 315 3.1E-35 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_23920 152bc54eacecc3d14c8f8a17414838ac 420 SUPERFAMILY SSF103473 1 415 2.35E-64 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_23920 152bc54eacecc3d14c8f8a17414838ac 420 PRINTS PR01035 Tetracycline resistance protein signature 155 177 3.3E-8 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 LH59_23920 152bc54eacecc3d14c8f8a17414838ac 420 PRINTS PR01035 Tetracycline resistance protein signature 36 52 3.3E-8 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 LH59_23920 152bc54eacecc3d14c8f8a17414838ac 420 PRINTS PR01035 Tetracycline resistance protein signature 98 122 3.3E-8 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 LH59_23920 152bc54eacecc3d14c8f8a17414838ac 420 PRINTS PR01035 Tetracycline resistance protein signature 360 383 3.3E-8 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 LH59_23920 152bc54eacecc3d14c8f8a17414838ac 420 PRINTS PR01035 Tetracycline resistance protein signature 125 146 3.3E-8 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 LH59_23920 152bc54eacecc3d14c8f8a17414838ac 420 Gene3D G3DSA:1.20.1250.20 20 407 5.4E-62 T 14-10-2018 LH59_09110 6dd83615f6fd031962a5aa1d4005fcf8 206 Gene3D G3DSA:2.30.30.240 113 206 4.2E-23 T 14-10-2018 LH59_09110 6dd83615f6fd031962a5aa1d4005fcf8 206 Gene3D G3DSA:2.40.30.60 13 111 2.0E-26 T 14-10-2018 IPR036976 RimM, N-terminal domain superfamily GO:0006364 LH59_09110 6dd83615f6fd031962a5aa1d4005fcf8 206 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 15 204 9.4E-37 T 14-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 LH59_09110 6dd83615f6fd031962a5aa1d4005fcf8 206 Pfam PF01782 RimM N-terminal domain 16 106 1.7E-23 T 14-10-2018 IPR002676 RimM, N-terminal GO:0006364 LH59_09110 6dd83615f6fd031962a5aa1d4005fcf8 206 SUPERFAMILY SSF50447 13 110 2.44E-17 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily LH59_09110 6dd83615f6fd031962a5aa1d4005fcf8 206 SUPERFAMILY SSF50346 117 205 2.12E-11 T 14-10-2018 IPR011033 PRC-barrel-like superfamily LH59_09110 6dd83615f6fd031962a5aa1d4005fcf8 206 Pfam PF05239 PRC-barrel domain 114 197 6.1E-5 T 14-10-2018 IPR027275 PRC-barrel domain LH59_09110 6dd83615f6fd031962a5aa1d4005fcf8 206 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 14 205 23.286 T 14-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 LH59_22175 754c3a471a0548c5812443e24650595a 162 Pfam PF04073 Aminoacyl-tRNA editing domain 37 150 1.8E-27 T 14-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 LH59_22175 754c3a471a0548c5812443e24650595a 162 SUPERFAMILY SSF55826 10 159 1.7E-43 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 LH59_22175 754c3a471a0548c5812443e24650595a 162 Gene3D G3DSA:3.90.960.10 3 161 6.3E-49 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 LH59_22175 754c3a471a0548c5812443e24650595a 162 PIRSF PIRSF006181 5 162 9.7E-48 T 14-10-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC LH59_22175 754c3a471a0548c5812443e24650595a 162 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 10 157 4.1E-49 T 14-10-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC LH59_16410 be043abe5ddb75b10a6a4b00fbb05851 299 Pfam PF03466 LysR substrate binding domain 88 290 4.6E-38 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_16410 be043abe5ddb75b10a6a4b00fbb05851 299 SUPERFAMILY SSF53850 90 296 1.99E-38 T 14-10-2018 LH59_16410 be043abe5ddb75b10a6a4b00fbb05851 299 Gene3D G3DSA:1.10.10.10 2 89 4.0E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_16410 be043abe5ddb75b10a6a4b00fbb05851 299 SUPERFAMILY SSF46785 3 112 4.95E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_16410 be043abe5ddb75b10a6a4b00fbb05851 299 Gene3D G3DSA:3.40.190.290 92 293 2.5E-57 T 14-10-2018 LH59_16410 be043abe5ddb75b10a6a4b00fbb05851 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 3.0E-16 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_01255 f02a820c39d19b2fc532a16436717993 310 Gene3D G3DSA:3.40.50.1980 23 138 2.8E-25 T 14-10-2018 LH59_01255 f02a820c39d19b2fc532a16436717993 310 Pfam PF01497 Periplasmic binding protein 50 287 3.4E-21 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain LH59_01255 f02a820c39d19b2fc532a16436717993 310 Gene3D G3DSA:3.40.50.1980 139 310 2.9E-57 T 14-10-2018 LH59_01255 f02a820c39d19b2fc532a16436717993 310 SUPERFAMILY SSF53807 31 295 1.77E-35 T 14-10-2018 LH59_08985 e5ddaec15c3813878b6440f54f10d376 419 SMART SM00382 170 337 4.9E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_08985 e5ddaec15c3813878b6440f54f10d376 419 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 419 243.105 T 14-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 LH59_08985 e5ddaec15c3813878b6440f54f10d376 419 SUPERFAMILY SSF68912 1 46 8.24E-12 T 14-10-2018 IPR036269 Rho termination factor, N-terminal domain superfamily LH59_08985 e5ddaec15c3813878b6440f54f10d376 419 TIGRFAM TIGR00767 rho: transcription termination factor Rho 2 418 8.7E-209 T 14-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 LH59_08985 e5ddaec15c3813878b6440f54f10d376 419 Gene3D G3DSA:2.40.50.140 47 123 3.7E-33 T 14-10-2018 LH59_08985 e5ddaec15c3813878b6440f54f10d376 419 SMART SM00357 52 118 5.7E-17 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 LH59_08985 e5ddaec15c3813878b6440f54f10d376 419 SMART SM00959 5 47 4.3E-17 T 14-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 LH59_08985 e5ddaec15c3813878b6440f54f10d376 419 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 160 363 4.9E-24 T 14-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 LH59_08985 e5ddaec15c3813878b6440f54f10d376 419 Pfam PF07497 Rho termination factor, RNA-binding domain 52 125 8.0E-31 T 14-10-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 LH59_08985 e5ddaec15c3813878b6440f54f10d376 419 Gene3D G3DSA:1.10.720.10 1 46 1.2E-18 T 14-10-2018 LH59_08985 e5ddaec15c3813878b6440f54f10d376 419 SUPERFAMILY SSF50249 49 125 6.28E-28 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_08985 e5ddaec15c3813878b6440f54f10d376 419 Gene3D G3DSA:3.40.50.300 130 417 6.4E-127 T 14-10-2018 LH59_08985 e5ddaec15c3813878b6440f54f10d376 419 SUPERFAMILY SSF52540 90 371 2.66E-67 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_08985 e5ddaec15c3813878b6440f54f10d376 419 Pfam PF07498 Rho termination factor, N-terminal domain 5 47 6.4E-16 T 14-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 LH59_14535 27ce69a89d84ddf8944f1fcee14e247b 215 Gene3D G3DSA:1.20.120.700 5 64 4.6E-17 T 14-10-2018 LH59_14535 27ce69a89d84ddf8944f1fcee14e247b 215 Pfam PF02613 Nitrate reductase delta subunit 33 155 8.5E-13 T 14-10-2018 IPR020945 DMSO/Nitrate reductase chaperone LH59_14535 27ce69a89d84ddf8944f1fcee14e247b 215 Gene3D G3DSA:1.10.4070.10 65 139 4.6E-17 T 14-10-2018 LH59_14535 27ce69a89d84ddf8944f1fcee14e247b 215 TIGRFAM TIGR00684 narJ: nitrate reductase molybdenum cofactor assembly chaperone 8 157 6.1E-38 T 14-10-2018 IPR003765 Nitrate reductase chaperone, NarJ GO:0051082|GO:0051131 LH59_14535 27ce69a89d84ddf8944f1fcee14e247b 215 SUPERFAMILY SSF89155 2 159 5.62E-36 T 14-10-2018 IPR036411 TorD-like superfamily LH59_10090 50421b6a09e21f1ade88147dc16e396b 301 Gene3D G3DSA:3.40.190.10 163 263 3.2E-58 T 14-10-2018 LH59_10090 50421b6a09e21f1ade88147dc16e396b 301 SUPERFAMILY SSF46785 4 83 2.55E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_10090 50421b6a09e21f1ade88147dc16e396b 301 Gene3D G3DSA:3.40.190.10 91 289 3.2E-58 T 14-10-2018 LH59_10090 50421b6a09e21f1ade88147dc16e396b 301 Gene3D G3DSA:1.10.10.10 3 88 1.1E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_10090 50421b6a09e21f1ade88147dc16e396b 301 SUPERFAMILY SSF53850 90 295 3.62E-40 T 14-10-2018 LH59_10090 50421b6a09e21f1ade88147dc16e396b 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 1.2E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_10090 50421b6a09e21f1ade88147dc16e396b 301 Pfam PF03466 LysR substrate binding domain 89 292 3.3E-36 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_02535 9dbdf34f34e8b208912502a404e837e1 302 SUPERFAMILY SSF53807 33 294 3.08E-56 T 14-10-2018 LH59_02535 9dbdf34f34e8b208912502a404e837e1 302 Gene3D G3DSA:3.40.50.1980 169 298 2.6E-27 T 14-10-2018 LH59_02535 9dbdf34f34e8b208912502a404e837e1 302 Gene3D G3DSA:3.40.50.1980 49 168 1.1E-27 T 14-10-2018 LH59_02535 9dbdf34f34e8b208912502a404e837e1 302 Pfam PF01497 Periplasmic binding protein 53 276 2.1E-18 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain LH59_02900 cdddc82d9e4d35246712c6aca80502b8 266 Gene3D G3DSA:3.40.50.300 1 262 1.9E-55 T 14-10-2018 LH59_02900 cdddc82d9e4d35246712c6aca80502b8 266 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 232 254 7.1E-12 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal LH59_02900 cdddc82d9e4d35246712c6aca80502b8 266 SUPERFAMILY SSF52540 11 255 1.55E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_02900 cdddc82d9e4d35246712c6aca80502b8 266 SMART SM00382 37 256 1.8E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_02900 cdddc82d9e4d35246712c6aca80502b8 266 Pfam PF00005 ABC transporter 29 185 7.0E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_21745 6ebf37645efdc1667814de944227a934 863 TIGRFAM TIGR00117 acnB: aconitate hydratase 2 1 856 0.0 T 14-10-2018 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 LH59_21745 6ebf37645efdc1667814de944227a934 863 Gene3D G3DSA:3.30.499.10 405 532 2.0E-150 T 14-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 LH59_21745 6ebf37645efdc1667814de944227a934 863 Gene3D G3DSA:1.25.40.310 1 161 2.0E-67 T 14-10-2018 IPR036288 Aconitase B, HEAT-like domain superfamily GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 LH59_21745 6ebf37645efdc1667814de944227a934 863 Gene3D G3DSA:3.20.19.10 162 361 2.0E-70 T 14-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 LH59_21745 6ebf37645efdc1667814de944227a934 863 SUPERFAMILY SSF52016 162 372 2.94E-65 T 14-10-2018 LH59_21745 6ebf37645efdc1667814de944227a934 863 Pfam PF06434 Aconitate hydratase 2 N-terminus 168 382 2.0E-95 T 14-10-2018 IPR015929 Aconitase B, swivel GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 LH59_21745 6ebf37645efdc1667814de944227a934 863 ProSitePatterns PS00450 Aconitase family signature 1. 705 722 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 LH59_21745 6ebf37645efdc1667814de944227a934 863 SUPERFAMILY SSF74778 1 160 2.09E-66 T 14-10-2018 IPR036288 Aconitase B, HEAT-like domain superfamily GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 LH59_21745 6ebf37645efdc1667814de944227a934 863 Pfam PF11791 Aconitate B N-terminal domain 5 156 1.6E-64 T 14-10-2018 IPR015933 Aconitase B, HEAT-like domain GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 LH59_21745 6ebf37645efdc1667814de944227a934 863 Gene3D G3DSA:3.30.499.10 686 863 2.0E-64 T 14-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 LH59_21745 6ebf37645efdc1667814de944227a934 863 PIRSF PIRSF036687 1 861 0.0 T 14-10-2018 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 LH59_21745 6ebf37645efdc1667814de944227a934 863 SUPERFAMILY SSF53732 380 855 8.76E-145 T 14-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 LH59_21745 6ebf37645efdc1667814de944227a934 863 ProSitePatterns PS01244 Aconitase family signature 2. 763 776 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 LH59_21745 6ebf37645efdc1667814de944227a934 863 Gene3D G3DSA:3.40.1060.10 385 684 2.0E-150 T 14-10-2018 IPR015932 Aconitase, domain 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-1268020|Reactome: R-HSA-71403 LH59_21745 6ebf37645efdc1667814de944227a934 863 Pfam PF00330 Aconitase family (aconitate hydratase) 474 816 2.7E-39 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 LH59_01720 99d7f3679f6242ca22e29f583f6b8c9e 809 SUPERFAMILY SSF53706 1 641 3.27E-223 T 14-10-2018 LH59_01720 99d7f3679f6242ca22e29f583f6b8c9e 809 Gene3D G3DSA:3.40.50.740 303 472 3.7E-56 T 14-10-2018 LH59_01720 99d7f3679f6242ca22e29f583f6b8c9e 809 SUPERFAMILY SSF50692 620 809 1.28E-43 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily LH59_01720 99d7f3679f6242ca22e29f583f6b8c9e 809 Gene3D G3DSA:3.40.228.10 1 275 2.8E-71 T 14-10-2018 LH59_01720 99d7f3679f6242ca22e29f583f6b8c9e 809 Gene3D G3DSA:2.40.40.20 631 809 1.1E-69 T 14-10-2018 LH59_01720 99d7f3679f6242ca22e29f583f6b8c9e 809 Gene3D G3DSA:3.40.228.10 549 630 3.5E-24 T 14-10-2018 LH59_01720 99d7f3679f6242ca22e29f583f6b8c9e 809 Pfam PF00384 Molybdopterin oxidoreductase 2 378 1.2E-19 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_01720 99d7f3679f6242ca22e29f583f6b8c9e 809 TIGRFAM TIGR01553 formate-DH-alph: formate dehydrogenase-N alpha subunit 1 808 0.0 T 14-10-2018 IPR006443 Formate dehydrogenase-N, alpha subunit GO:0008863|GO:0009055|GO:0043546|GO:0045333|GO:0047111 LH59_01720 99d7f3679f6242ca22e29f583f6b8c9e 809 Pfam PF01568 Molydopterin dinucleotide binding domain 686 802 2.3E-15 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 LH59_21460 7ae7e9da2c95a66d2a89d5e4c4c000e2 401 SUPERFAMILY SSF53822 29 384 1.72E-84 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_21460 7ae7e9da2c95a66d2a89d5e4c4c000e2 401 Gene3D G3DSA:3.40.50.2300 148 373 5.4E-123 T 14-10-2018 LH59_21460 7ae7e9da2c95a66d2a89d5e4c4c000e2 401 Pfam PF13458 Periplasmic binding protein 30 366 2.8E-72 T 14-10-2018 IPR028081 Leucine-binding protein domain LH59_21460 7ae7e9da2c95a66d2a89d5e4c4c000e2 401 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 338 353 1.4E-7 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 LH59_21460 7ae7e9da2c95a66d2a89d5e4c4c000e2 401 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 70 88 1.4E-7 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 LH59_21460 7ae7e9da2c95a66d2a89d5e4c4c000e2 401 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 286 299 1.4E-7 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 LH59_21460 7ae7e9da2c95a66d2a89d5e4c4c000e2 401 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 51 67 1.4E-7 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 LH59_21460 7ae7e9da2c95a66d2a89d5e4c4c000e2 401 Gene3D G3DSA:3.40.50.2300 49 361 5.4E-123 T 14-10-2018 LH59_24210 859e070537256d76e4497ebe2de55169 391 SUPERFAMILY SSF51604 123 382 5.11E-45 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily LH59_24210 859e070537256d76e4497ebe2de55169 391 Pfam PF13378 Enolase C-terminal domain-like 167 377 6.2E-38 T 14-10-2018 IPR029065 Enolase C-terminal domain-like LH59_24210 859e070537256d76e4497ebe2de55169 391 Gene3D G3DSA:3.30.390.10 1 127 3.8E-57 T 14-10-2018 IPR029017 Enolase-like, N-terminal LH59_24210 859e070537256d76e4497ebe2de55169 391 SUPERFAMILY SSF54826 1 138 3.54E-22 T 14-10-2018 LH59_24210 859e070537256d76e4497ebe2de55169 391 SMART SM00922 164 261 1.6E-12 T 14-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal LH59_24210 859e070537256d76e4497ebe2de55169 391 Gene3D G3DSA:3.20.20.120 128 384 2.2E-59 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily LH59_23005 73b5867c07daadbb003521b416f76589 441 Pfam PF01794 Ferric reductase like transmembrane component 45 173 1.7E-17 T 14-10-2018 IPR013130 Ferric reductase transmembrane component-like domain LH59_23005 73b5867c07daadbb003521b416f76589 441 Gene3D G3DSA:3.40.50.80 312 441 5.5E-20 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain LH59_23005 73b5867c07daadbb003521b416f76589 441 SUPERFAMILY SSF63380 218 311 4.12E-16 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel LH59_23005 73b5867c07daadbb003521b416f76589 441 SUPERFAMILY SSF52343 312 438 7.6E-22 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain LH59_23005 73b5867c07daadbb003521b416f76589 441 Pfam PF08022 FAD-binding domain 225 310 7.4E-8 T 14-10-2018 IPR013112 FAD-binding 8 GO:0016491|GO:0055114 LH59_23005 73b5867c07daadbb003521b416f76589 441 Gene3D G3DSA:2.40.30.10 211 309 1.0E-13 T 14-10-2018 LH59_09095 5a50e2ece81b2a8ecf39ad06cf59cbc6 89 Gene3D G3DSA:3.30.110.40 11 89 1.6E-25 T 14-10-2018 IPR036868 TusA-like domain superfamily LH59_09095 5a50e2ece81b2a8ecf39ad06cf59cbc6 89 Pfam PF01206 Sulfurtransferase TusA 20 82 4.9E-20 T 14-10-2018 IPR001455 TusA-like domain LH59_09095 5a50e2ece81b2a8ecf39ad06cf59cbc6 89 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 21 45 - T 14-10-2018 IPR001455 TusA-like domain LH59_09095 5a50e2ece81b2a8ecf39ad06cf59cbc6 89 SUPERFAMILY SSF64307 5 88 1.03E-20 T 14-10-2018 IPR036868 TusA-like domain superfamily LH59_08630 8cdc3de440f375ade30a5cd517d30dfc 367 PIRSF PIRSF019574 1 367 2.8E-140 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 LH59_08630 8cdc3de440f375ade30a5cd517d30dfc 367 Pfam PF13416 Bacterial extracellular solute-binding protein 47 332 3.1E-37 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein LH59_08630 8cdc3de440f375ade30a5cd517d30dfc 367 Gene3D G3DSA:3.40.190.10 134 360 3.0E-130 T 14-10-2018 LH59_08630 8cdc3de440f375ade30a5cd517d30dfc 367 SUPERFAMILY SSF53850 28 366 2.82E-97 T 14-10-2018 LH59_08630 8cdc3de440f375ade30a5cd517d30dfc 367 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 266 285 3.4E-64 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 LH59_08630 8cdc3de440f375ade30a5cd517d30dfc 367 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 216 235 3.4E-64 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 LH59_08630 8cdc3de440f375ade30a5cd517d30dfc 367 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 311 337 3.4E-64 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 LH59_08630 8cdc3de440f375ade30a5cd517d30dfc 367 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 49 70 3.4E-64 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 LH59_08630 8cdc3de440f375ade30a5cd517d30dfc 367 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 92 105 3.4E-64 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 LH59_08630 8cdc3de440f375ade30a5cd517d30dfc 367 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 76 90 3.4E-64 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 LH59_08630 8cdc3de440f375ade30a5cd517d30dfc 367 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 156 170 3.4E-64 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 LH59_08630 8cdc3de440f375ade30a5cd517d30dfc 367 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 125 141 3.4E-64 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 LH59_08630 8cdc3de440f375ade30a5cd517d30dfc 367 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 179 198 3.4E-64 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 LH59_08630 8cdc3de440f375ade30a5cd517d30dfc 367 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 33 49 3.4E-64 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 LH59_08630 8cdc3de440f375ade30a5cd517d30dfc 367 Gene3D G3DSA:3.40.190.10 30 335 3.0E-130 T 14-10-2018 LH59_10525 23de95015c7bc4d4c426af84088c2936 158 Gene3D G3DSA:1.10.1130.10 61 128 4.9E-28 T 14-10-2018 LH59_10525 23de95015c7bc4d4c426af84088c2936 158 SUPERFAMILY SSF48695 28 145 4.49E-45 T 14-10-2018 IPR036280 Multiheme cytochrome superfamily LH59_10525 23de95015c7bc4d4c426af84088c2936 158 PIRSF PIRSF006105 2 156 8.5E-54 T 14-10-2018 IPR005591 Nitrate reductase cytochrome c-type subunit NapB LH59_10525 23de95015c7bc4d4c426af84088c2936 158 Pfam PF03892 Nitrate reductase cytochrome c-type subunit (NapB) 26 142 9.8E-48 T 14-10-2018 IPR005591 Nitrate reductase cytochrome c-type subunit NapB LH59_15825 6d7ad0a2ec130c4d3e3d854b44d5064a 509 Gene3D G3DSA:1.20.1250.20 260 433 2.0E-9 T 14-10-2018 LH59_15825 6d7ad0a2ec130c4d3e3d854b44d5064a 509 Gene3D G3DSA:1.20.1720.10 15 222 1.0E-34 T 14-10-2018 LH59_15825 6d7ad0a2ec130c4d3e3d854b44d5064a 509 SUPERFAMILY SSF103473 8 496 3.53E-46 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_15825 6d7ad0a2ec130c4d3e3d854b44d5064a 509 Pfam PF07690 Major Facilitator Superfamily 20 403 5.5E-38 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_05905 83d97b3ebc41376c5e01ff8fdaf09768 509 SMART SM00387 254 375 1.7E-31 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_05905 83d97b3ebc41376c5e01ff8fdaf09768 509 PRINTS PR00344 Bacterial sensor protein C-terminal signature 335 353 4.9E-18 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_05905 83d97b3ebc41376c5e01ff8fdaf09768 509 PRINTS PR00344 Bacterial sensor protein C-terminal signature 304 318 4.9E-18 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_05905 83d97b3ebc41376c5e01ff8fdaf09768 509 PRINTS PR00344 Bacterial sensor protein C-terminal signature 359 372 4.9E-18 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_05905 83d97b3ebc41376c5e01ff8fdaf09768 509 PRINTS PR00344 Bacterial sensor protein C-terminal signature 322 332 4.9E-18 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_05905 83d97b3ebc41376c5e01ff8fdaf09768 509 Gene3D G3DSA:3.40.50.2300 386 509 3.4E-26 T 14-10-2018 LH59_05905 83d97b3ebc41376c5e01ff8fdaf09768 509 SUPERFAMILY SSF55874 204 373 4.58E-39 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_05905 83d97b3ebc41376c5e01ff8fdaf09768 509 SMART SM00448 396 506 1.5E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_05905 83d97b3ebc41376c5e01ff8fdaf09768 509 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 7 130 3.9E-20 T 14-10-2018 IPR000014 PAS domain LH59_05905 83d97b3ebc41376c5e01ff8fdaf09768 509 SMART SM00086 83 125 6.4E-4 T 14-10-2018 IPR001610 PAC motif LH59_05905 83d97b3ebc41376c5e01ff8fdaf09768 509 SUPERFAMILY SSF55785 7 117 3.66E-25 T 14-10-2018 IPR035965 PAS domain superfamily LH59_05905 83d97b3ebc41376c5e01ff8fdaf09768 509 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 255 373 1.5E-19 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_05905 83d97b3ebc41376c5e01ff8fdaf09768 509 Pfam PF00512 His Kinase A (phospho-acceptor) domain 149 211 4.9E-10 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_05905 83d97b3ebc41376c5e01ff8fdaf09768 509 Pfam PF13426 PAS domain 22 124 6.7E-14 T 14-10-2018 IPR000014 PAS domain LH59_05905 83d97b3ebc41376c5e01ff8fdaf09768 509 SUPERFAMILY SSF47384 139 210 1.96E-11 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 LH59_05905 83d97b3ebc41376c5e01ff8fdaf09768 509 SUPERFAMILY SSF52172 395 509 5.41E-28 T 14-10-2018 IPR011006 CheY-like superfamily LH59_05905 83d97b3ebc41376c5e01ff8fdaf09768 509 SMART SM00091 9 78 6.6E-6 T 14-10-2018 IPR000014 PAS domain LH59_05905 83d97b3ebc41376c5e01ff8fdaf09768 509 Gene3D G3DSA:3.30.565.10 214 381 1.7E-43 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_05905 83d97b3ebc41376c5e01ff8fdaf09768 509 Gene3D G3DSA:3.30.450.20 7 141 3.4E-27 T 14-10-2018 LH59_05905 83d97b3ebc41376c5e01ff8fdaf09768 509 Pfam PF00072 Response regulator receiver domain 398 505 3.5E-19 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_05905 83d97b3ebc41376c5e01ff8fdaf09768 509 Gene3D G3DSA:1.10.287.130 142 211 2.6E-17 T 14-10-2018 LH59_05905 83d97b3ebc41376c5e01ff8fdaf09768 509 SMART SM00388 147 213 2.5E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_05520 50e7a5be2c9a238412e21c8f22149eff 422 SMART SM01119 310 409 3.9E-37 T 14-10-2018 IPR026956 D-serine dehydratase-like domain LH59_05520 50e7a5be2c9a238412e21c8f22149eff 422 Gene3D G3DSA:3.20.20.10 52 284 1.7E-144 T 14-10-2018 IPR029066 PLP-binding barrel LH59_05520 50e7a5be2c9a238412e21c8f22149eff 422 Pfam PF14031 Putative serine dehydratase domain 310 408 6.8E-17 T 14-10-2018 IPR026956 D-serine dehydratase-like domain LH59_05520 50e7a5be2c9a238412e21c8f22149eff 422 SUPERFAMILY SSF51419 52 283 1.41E-29 T 14-10-2018 IPR029066 PLP-binding barrel LH59_05520 50e7a5be2c9a238412e21c8f22149eff 422 Pfam PF01168 Alanine racemase, N-terminal domain 52 251 2.4E-10 T 14-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LH59_05520 50e7a5be2c9a238412e21c8f22149eff 422 Gene3D G3DSA:2.40.37.20 33 422 1.7E-144 T 14-10-2018 LH59_15835 c71388f880220abf89e8836d80004bb3 756 Pfam PF13307 Helicase C-terminal domain 593 754 5.6E-32 T 14-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 LH59_15835 c71388f880220abf89e8836d80004bb3 756 SUPERFAMILY SSF52540 195 738 4.41E-13 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_15835 c71388f880220abf89e8836d80004bb3 756 SMART SM00491 605 742 2.7E-11 T 14-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 LH59_15835 c71388f880220abf89e8836d80004bb3 756 Gene3D G3DSA:3.40.50.300 184 543 4.8E-34 T 14-10-2018 LH59_15835 c71388f880220abf89e8836d80004bb3 756 Gene3D G3DSA:1.10.275.30 384 506 4.8E-34 T 14-10-2018 LH59_15835 c71388f880220abf89e8836d80004bb3 756 Pfam PF06733 DEAD_2 268 388 9.9E-12 T 14-10-2018 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 LH59_15835 c71388f880220abf89e8836d80004bb3 756 Gene3D G3DSA:3.40.50.300 558 756 2.2E-47 T 14-10-2018 LH59_08695 c27292bce81467804781ac11c6a79a57 90 ProDom PD029191 TRAFFICKING IRON PROBABLE FE2 YGGX FEII 3D-STRUCTURE OXIDATIVE CONTROL DIRECT 1 76 1.0E-37 T 14-10-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 LH59_08695 c27292bce81467804781ac11c6a79a57 90 Hamap MF_00686 Probable Fe(2+)-trafficking protein [yggX]. 1 88 29.139 T 14-10-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 LH59_08695 c27292bce81467804781ac11c6a79a57 90 Pfam PF04362 Bacterial Fe(2+) trafficking 1 88 3.2E-42 T 14-10-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 LH59_08695 c27292bce81467804781ac11c6a79a57 90 PIRSF PIRSF029827 1 90 7.2E-42 T 14-10-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 LH59_08695 c27292bce81467804781ac11c6a79a57 90 Gene3D G3DSA:1.10.3880.10 1 90 8.4E-40 T 14-10-2018 IPR036766 Fe(II) trafficking protein YggX superfamily GO:0005506 LH59_08695 c27292bce81467804781ac11c6a79a57 90 SUPERFAMILY SSF111148 1 89 6.93E-39 T 14-10-2018 IPR036766 Fe(II) trafficking protein YggX superfamily GO:0005506 LH59_11715 776c762a217fec03c2e2c16a96fffefc 202 SUPERFAMILY SSF53098 12 197 5.31E-62 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily LH59_11715 776c762a217fec03c2e2c16a96fffefc 202 Gene3D G3DSA:3.30.420.10 6 200 3.6E-68 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 LH59_11715 776c762a217fec03c2e2c16a96fffefc 202 Hamap MF_00052_B Ribonuclease HII [rnhB]. 16 195 34.387 T 14-10-2018 IPR022898 Ribonuclease HII GO:0004523 LH59_11715 776c762a217fec03c2e2c16a96fffefc 202 Pfam PF01351 Ribonuclease HII 18 193 2.9E-32 T 14-10-2018 IPR024567 Ribonuclease HII/HIII domain LH59_01690 04f485cf671ed2dd54e535a1f6f744c9 326 Gene3D G3DSA:2.130.10.10 7 122 2.7E-17 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 LH59_01690 04f485cf671ed2dd54e535a1f6f744c9 326 SUPERFAMILY SSF50974 6 319 3.66E-71 T 14-10-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 LH59_01690 04f485cf671ed2dd54e535a1f6f744c9 326 Gene3D G3DSA:2.130.10.10 123 325 5.1E-40 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 LH59_14415 c23eda22a4039583460b26f3d7d260d2 233 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 76 3.9E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_14415 c23eda22a4039583460b26f3d7d260d2 233 SMART SM00895 86 210 7.8E-15 T 14-10-2018 IPR011711 GntR, C-terminal LH59_14415 c23eda22a4039583460b26f3d7d260d2 233 Gene3D G3DSA:1.20.120.530 82 221 2.7E-23 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_14415 c23eda22a4039583460b26f3d7d260d2 233 SUPERFAMILY SSF48008 85 217 6.02E-24 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_14415 c23eda22a4039583460b26f3d7d260d2 233 SUPERFAMILY SSF46785 9 80 8.92E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_14415 c23eda22a4039583460b26f3d7d260d2 233 SMART SM00345 18 76 3.4E-9 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_14415 c23eda22a4039583460b26f3d7d260d2 233 Gene3D G3DSA:1.10.10.10 13 77 3.0E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_14415 c23eda22a4039583460b26f3d7d260d2 233 Pfam PF07729 FCD domain 90 208 1.0E-20 T 14-10-2018 IPR011711 GntR, C-terminal LH59_13130 1abb9baab8bdf1bfa9053c97bf910dd6 1004 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 489 583 5.2E-12 T 14-10-2018 IPR000014 PAS domain LH59_13130 1abb9baab8bdf1bfa9053c97bf910dd6 1004 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 188 313 1.9E-6 T 14-10-2018 IPR000014 PAS domain LH59_13130 1abb9baab8bdf1bfa9053c97bf910dd6 1004 SUPERFAMILY SSF55785 178 304 1.71E-13 T 14-10-2018 IPR035965 PAS domain superfamily LH59_13130 1abb9baab8bdf1bfa9053c97bf910dd6 1004 SUPERFAMILY SSF55785 492 597 2.9E-17 T 14-10-2018 IPR035965 PAS domain superfamily LH59_13130 1abb9baab8bdf1bfa9053c97bf910dd6 1004 Pfam PF08447 PAS fold 509 580 1.3E-11 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 LH59_13130 1abb9baab8bdf1bfa9053c97bf910dd6 1004 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 728 847 2.0E-14 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_13130 1abb9baab8bdf1bfa9053c97bf910dd6 1004 SUPERFAMILY SSF52172 875 991 7.54E-27 T 14-10-2018 IPR011006 CheY-like superfamily LH59_13130 1abb9baab8bdf1bfa9053c97bf910dd6 1004 SMART SM00388 618 686 8.9E-7 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_13130 1abb9baab8bdf1bfa9053c97bf910dd6 1004 SUPERFAMILY SSF55781 55 189 3.05E-20 T 14-10-2018 LH59_13130 1abb9baab8bdf1bfa9053c97bf910dd6 1004 Gene3D G3DSA:3.30.565.10 687 851 9.9E-38 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_13130 1abb9baab8bdf1bfa9053c97bf910dd6 1004 Gene3D G3DSA:3.30.450.20 492 591 1.8E-18 T 14-10-2018 LH59_13130 1abb9baab8bdf1bfa9053c97bf910dd6 1004 SMART SM00387 727 850 3.3E-24 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_13130 1abb9baab8bdf1bfa9053c97bf910dd6 1004 SMART SM00448 873 985 7.4E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_13130 1abb9baab8bdf1bfa9053c97bf910dd6 1004 Pfam PF00072 Response regulator receiver domain 875 986 1.3E-16 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_13130 1abb9baab8bdf1bfa9053c97bf910dd6 1004 Gene3D G3DSA:3.30.450.40 34 188 1.8E-29 T 14-10-2018 IPR029016 GAF-like domain superfamily LH59_13130 1abb9baab8bdf1bfa9053c97bf910dd6 1004 Gene3D G3DSA:3.40.50.2300 870 1001 9.4E-25 T 14-10-2018 LH59_13130 1abb9baab8bdf1bfa9053c97bf910dd6 1004 SMART SM00091 485 551 6.6E-9 T 14-10-2018 IPR000014 PAS domain LH59_13130 1abb9baab8bdf1bfa9053c97bf910dd6 1004 SMART SM00091 191 265 2.7 T 14-10-2018 IPR000014 PAS domain LH59_13130 1abb9baab8bdf1bfa9053c97bf910dd6 1004 SUPERFAMILY SSF55874 677 848 2.88E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_13130 1abb9baab8bdf1bfa9053c97bf910dd6 1004 Gene3D G3DSA:1.10.287.130 610 684 1.3E-18 T 14-10-2018 LH59_13130 1abb9baab8bdf1bfa9053c97bf910dd6 1004 Pfam PF13185 GAF domain 35 178 2.3E-12 T 14-10-2018 IPR003018 GAF domain GO:0005515 LH59_13130 1abb9baab8bdf1bfa9053c97bf910dd6 1004 Pfam PF08448 PAS fold 219 307 3.0E-8 T 14-10-2018 IPR013656 PAS fold-4 LH59_13130 1abb9baab8bdf1bfa9053c97bf910dd6 1004 PRINTS PR00344 Bacterial sensor protein C-terminal signature 797 807 8.0E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_13130 1abb9baab8bdf1bfa9053c97bf910dd6 1004 PRINTS PR00344 Bacterial sensor protein C-terminal signature 810 828 8.0E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_13130 1abb9baab8bdf1bfa9053c97bf910dd6 1004 PRINTS PR00344 Bacterial sensor protein C-terminal signature 779 793 8.0E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_13130 1abb9baab8bdf1bfa9053c97bf910dd6 1004 PRINTS PR00344 Bacterial sensor protein C-terminal signature 834 847 8.0E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_13130 1abb9baab8bdf1bfa9053c97bf910dd6 1004 Gene3D G3DSA:3.30.450.20 189 305 7.7E-16 T 14-10-2018 LH59_13130 1abb9baab8bdf1bfa9053c97bf910dd6 1004 SUPERFAMILY SSF47384 610 683 3.53E-11 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 LH59_13130 1abb9baab8bdf1bfa9053c97bf910dd6 1004 SMART SM00065 34 187 1.5E-6 T 14-10-2018 IPR003018 GAF domain GO:0005515 LH59_13130 1abb9baab8bdf1bfa9053c97bf910dd6 1004 Pfam PF00512 His Kinase A (phospho-acceptor) domain 619 684 3.7E-8 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_12880 7e41be2db30fd0ef751bec1670e2bb99 375 SUPERFAMILY SSF53822 30 370 7.74E-94 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_12880 7e41be2db30fd0ef751bec1670e2bb99 375 Pfam PF13458 Periplasmic binding protein 30 366 5.3E-62 T 14-10-2018 IPR028081 Leucine-binding protein domain LH59_12880 7e41be2db30fd0ef751bec1670e2bb99 375 Gene3D G3DSA:3.40.50.2300 32 351 6.1E-113 T 14-10-2018 LH59_12880 7e41be2db30fd0ef751bec1670e2bb99 375 Gene3D G3DSA:3.40.50.2300 150 278 6.1E-113 T 14-10-2018 LH59_12880 7e41be2db30fd0ef751bec1670e2bb99 375 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 260 278 1.6E-34 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 LH59_12880 7e41be2db30fd0ef751bec1670e2bb99 375 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 335 350 1.6E-34 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 LH59_12880 7e41be2db30fd0ef751bec1670e2bb99 375 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 283 296 1.6E-34 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 LH59_12880 7e41be2db30fd0ef751bec1670e2bb99 375 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 93 103 1.6E-34 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 LH59_12880 7e41be2db30fd0ef751bec1670e2bb99 375 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 53 69 1.6E-34 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 LH59_12880 7e41be2db30fd0ef751bec1670e2bb99 375 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 31 47 1.6E-34 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 LH59_12880 7e41be2db30fd0ef751bec1670e2bb99 375 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 72 90 1.6E-34 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 LH59_19040 e03b47c3a951c7abaf863a37bb6f0dba 700 SUPERFAMILY SSF56059 479 699 6.6E-35 T 14-10-2018 LH59_19040 e03b47c3a951c7abaf863a37bb6f0dba 700 Gene3D G3DSA:3.30.1490.20 497 572 7.2E-56 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 LH59_19040 e03b47c3a951c7abaf863a37bb6f0dba 700 SMART SM00881 7 102 8.1E-32 T 14-10-2018 IPR003781 CoA-binding GO:0048037 LH59_19040 e03b47c3a951c7abaf863a37bb6f0dba 700 Pfam PF13380 CoA binding domain 11 134 1.5E-21 T 14-10-2018 IPR003781 CoA-binding GO:0048037 LH59_19040 e03b47c3a951c7abaf863a37bb6f0dba 700 Gene3D G3DSA:3.40.50.261 131 295 1.1E-49 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 LH59_19040 e03b47c3a951c7abaf863a37bb6f0dba 700 Gene3D G3DSA:3.40.50.720 2 129 8.5E-38 T 14-10-2018 LH59_19040 e03b47c3a951c7abaf863a37bb6f0dba 700 Gene3D G3DSA:3.30.470.20 478 691 7.2E-56 T 14-10-2018 LH59_19040 e03b47c3a951c7abaf863a37bb6f0dba 700 SUPERFAMILY SSF52210 301 453 7.2E-21 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 LH59_19040 e03b47c3a951c7abaf863a37bb6f0dba 700 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 156 292 7.6E-49 T 14-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain LH59_19040 e03b47c3a951c7abaf863a37bb6f0dba 700 Gene3D G3DSA:3.40.50.261 299 457 1.6E-27 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 LH59_19040 e03b47c3a951c7abaf863a37bb6f0dba 700 SUPERFAMILY SSF51735 5 136 2.46E-32 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_19040 e03b47c3a951c7abaf863a37bb6f0dba 700 SUPERFAMILY SSF52210 146 294 4.84E-40 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 LH59_19040 e03b47c3a951c7abaf863a37bb6f0dba 700 Pfam PF13549 ATP-grasp domain 476 691 9.4E-46 T 14-10-2018 LH59_20035 2c0651d08580d4dff0f4b824715baa09 533 SUPERFAMILY SSF75005 292 471 1.46E-12 T 14-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily LH59_03485 976c0d5ef3f2cbcd08e2b49c8e0b6f16 216 Gene3D G3DSA:3.40.30.10 1 213 8.6E-67 T 14-10-2018 LH59_03485 976c0d5ef3f2cbcd08e2b49c8e0b6f16 216 SUPERFAMILY SSF52833 4 214 7.27E-50 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_03485 976c0d5ef3f2cbcd08e2b49c8e0b6f16 216 Pfam PF01323 DSBA-like thioredoxin domain 5 209 8.1E-39 T 14-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 LH59_23685 9e9ab40249b576e50ca35ebbafbba662 346 Gene3D G3DSA:3.40.800.20 1 346 6.8E-114 T 14-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 LH59_23685 9e9ab40249b576e50ca35ebbafbba662 346 PRINTS PR01270 Histone deacetylase superfamily signature 193 208 1.4E-13 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 LH59_23685 9e9ab40249b576e50ca35ebbafbba662 346 PRINTS PR01270 Histone deacetylase superfamily signature 160 183 1.4E-13 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 LH59_23685 9e9ab40249b576e50ca35ebbafbba662 346 PRINTS PR01270 Histone deacetylase superfamily signature 279 289 1.4E-13 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 LH59_23685 9e9ab40249b576e50ca35ebbafbba662 346 SUPERFAMILY SSF52768 2 346 9.11E-86 T 14-10-2018 IPR023696 Ureohydrolase domain superfamily LH59_23685 9e9ab40249b576e50ca35ebbafbba662 346 Pfam PF00850 Histone deacetylase domain 28 342 3.0E-63 T 14-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 LH59_06465 e5fcdc3bda5161fbbeb403ddac116ede 261 Gene3D G3DSA:3.40.80.10 38 182 2.6E-48 T 14-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 LH59_06465 e5fcdc3bda5161fbbeb403ddac116ede 261 Pfam PF01471 Putative peptidoglycan binding domain 203 257 8.1E-11 T 14-10-2018 IPR002477 Peptidoglycan binding-like LH59_06465 e5fcdc3bda5161fbbeb403ddac116ede 261 Gene3D G3DSA:1.10.101.10 183 260 8.7E-23 T 14-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 LH59_06465 e5fcdc3bda5161fbbeb403ddac116ede 261 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 38 169 2.3E-28 T 14-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 LH59_06465 e5fcdc3bda5161fbbeb403ddac116ede 261 SMART SM00644 28 168 3.6E-28 T 14-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 LH59_06465 e5fcdc3bda5161fbbeb403ddac116ede 261 SUPERFAMILY SSF55846 29 184 2.49E-47 T 14-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 LH59_06465 e5fcdc3bda5161fbbeb403ddac116ede 261 SUPERFAMILY SSF47090 192 260 6.47E-19 T 14-10-2018 IPR036365 PGBD-like superfamily LH59_07710 ef9041f055f1ffb5d9414ce8d3d28dd5 463 Pfam PF03313 Serine dehydratase alpha chain 187 457 7.1E-105 T 14-10-2018 IPR005130 Serine dehydratase-like, alpha subunit LH59_07710 ef9041f055f1ffb5d9414ce8d3d28dd5 463 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 3 460 2.4E-210 T 14-10-2018 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 LH59_07710 ef9041f055f1ffb5d9414ce8d3d28dd5 463 Pfam PF03315 Serine dehydratase beta chain 4 156 9.8E-57 T 14-10-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 LH59_07710 ef9041f055f1ffb5d9414ce8d3d28dd5 463 Gene3D G3DSA:3.30.1330.90 11 160 2.8E-52 T 14-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 LH59_07710 ef9041f055f1ffb5d9414ce8d3d28dd5 463 SUPERFAMILY SSF143548 17 157 3.66E-45 T 14-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 LH59_01880 4a73ae75ba36dbd220cdcbca4b1a3e44 300 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 3.5E-18 T 14-10-2018 LH59_01880 4a73ae75ba36dbd220cdcbca4b1a3e44 300 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 248 270 3.5E-18 T 14-10-2018 LH59_01880 4a73ae75ba36dbd220cdcbca4b1a3e44 300 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 111 129 3.5E-18 T 14-10-2018 LH59_01880 4a73ae75ba36dbd220cdcbca4b1a3e44 300 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 154 172 3.5E-18 T 14-10-2018 LH59_01880 4a73ae75ba36dbd220cdcbca4b1a3e44 300 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 220 236 3.5E-18 T 14-10-2018 LH59_01880 4a73ae75ba36dbd220cdcbca4b1a3e44 300 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 273 8.0E-19 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LH59_01880 4a73ae75ba36dbd220cdcbca4b1a3e44 300 SUPERFAMILY SSF51905 1 294 4.49E-35 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_01880 4a73ae75ba36dbd220cdcbca4b1a3e44 300 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 2.1E-18 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 LH59_01880 4a73ae75ba36dbd220cdcbca4b1a3e44 300 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 150 174 2.1E-18 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 LH59_01880 4a73ae75ba36dbd220cdcbca4b1a3e44 300 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 276 295 2.1E-18 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 LH59_01880 4a73ae75ba36dbd220cdcbca4b1a3e44 300 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 112 120 2.1E-18 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 LH59_01880 4a73ae75ba36dbd220cdcbca4b1a3e44 300 Gene3D G3DSA:3.50.50.60 128 232 3.1E-42 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_01880 4a73ae75ba36dbd220cdcbca4b1a3e44 300 Gene3D G3DSA:3.50.50.60 8 289 3.1E-42 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_22875 25f1c1ccb52b49b024b3e6cd39a5f7cc 162 Gene3D G3DSA:3.30.70.640 6 162 1.4E-60 T 14-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 LH59_22875 25f1c1ccb52b49b024b3e6cd39a5f7cc 162 SUPERFAMILY SSF55040 15 159 1.01E-53 T 14-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 LH59_22875 25f1c1ccb52b49b024b3e6cd39a5f7cc 162 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase [moaC]. 6 162 31.786 T 14-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 LH59_22875 25f1c1ccb52b49b024b3e6cd39a5f7cc 162 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 8 156 3.9E-53 T 14-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 LH59_22875 25f1c1ccb52b49b024b3e6cd39a5f7cc 162 Pfam PF01967 MoaC family 20 154 1.5E-46 T 14-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 LH59_19395 5deffa6acb5555faa3228041d0aa1d44 717 PIRSF PIRSF000463 2 717 3.0E-268 T 14-10-2018 IPR037439 1,4-alpha-glucan-branching enzyme GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 LH59_19395 5deffa6acb5555faa3228041d0aa1d44 717 SUPERFAMILY SSF51011 613 715 6.75E-31 T 14-10-2018 LH59_19395 5deffa6acb5555faa3228041d0aa1d44 717 Gene3D G3DSA:2.60.40.10 1 212 6.0E-59 T 14-10-2018 IPR013783 Immunoglobulin-like fold LH59_19395 5deffa6acb5555faa3228041d0aa1d44 717 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 123 198 6.1E-20 T 14-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 LH59_19395 5deffa6acb5555faa3228041d0aa1d44 717 SUPERFAMILY SSF81296 10 97 5.25E-10 T 14-10-2018 IPR014756 Immunoglobulin E-set LH59_19395 5deffa6acb5555faa3228041d0aa1d44 717 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 618 712 3.4E-21 T 14-10-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 LH59_19395 5deffa6acb5555faa3228041d0aa1d44 717 SMART SM00642 242 586 2.2E-6 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 LH59_19395 5deffa6acb5555faa3228041d0aa1d44 717 Gene3D G3DSA:2.60.40.1180 613 716 5.0E-35 T 14-10-2018 IPR013780 Glycosyl hydrolase, all-beta LH59_19395 5deffa6acb5555faa3228041d0aa1d44 717 SUPERFAMILY SSF81296 130 185 1.33E-9 T 14-10-2018 IPR014756 Immunoglobulin E-set LH59_19395 5deffa6acb5555faa3228041d0aa1d44 717 Pfam PF00128 Alpha amylase, catalytic domain 260 338 8.3E-6 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 LH59_19395 5deffa6acb5555faa3228041d0aa1d44 717 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 105 711 1.7E-261 T 14-10-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 LH59_19395 5deffa6acb5555faa3228041d0aa1d44 717 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 92 715 42.742 T 14-10-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 LH59_19395 5deffa6acb5555faa3228041d0aa1d44 717 SUPERFAMILY SSF51445 172 606 1.44E-113 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily LH59_19395 5deffa6acb5555faa3228041d0aa1d44 717 Gene3D G3DSA:3.20.20.80 215 612 4.3E-159 T 14-10-2018 LH59_04185 96b7b5174b2bd9776ee71ed1d5970594 362 Gene3D G3DSA:3.30.70.260 256 354 2.2E-13 T 14-10-2018 LH59_04185 96b7b5174b2bd9776ee71ed1d5970594 362 Pfam PF09383 NIL domain 274 346 7.2E-15 T 14-10-2018 IPR018449 NIL domain LH59_04185 96b7b5174b2bd9776ee71ed1d5970594 362 SMART SM00930 272 347 6.0E-17 T 14-10-2018 IPR018449 NIL domain LH59_04185 96b7b5174b2bd9776ee71ed1d5970594 362 Pfam PF00005 ABC transporter 21 169 8.2E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_04185 96b7b5174b2bd9776ee71ed1d5970594 362 SUPERFAMILY SSF52540 1 239 2.73E-85 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_04185 96b7b5174b2bd9776ee71ed1d5970594 362 Gene3D G3DSA:3.40.50.300 1 244 1.1E-79 T 14-10-2018 LH59_04185 96b7b5174b2bd9776ee71ed1d5970594 362 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_04185 96b7b5174b2bd9776ee71ed1d5970594 362 SUPERFAMILY SSF55021 268 349 5.15E-14 T 14-10-2018 LH59_04185 96b7b5174b2bd9776ee71ed1d5970594 362 SMART SM00382 30 218 3.1E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_17780 7eeb7033138e0b27810fc5fe6bd1d356 303 SUPERFAMILY SSF53850 11 281 1.88E-39 T 14-10-2018 LH59_17780 7eeb7033138e0b27810fc5fe6bd1d356 303 Gene3D G3DSA:3.40.190.10 58 281 4.3E-68 T 14-10-2018 LH59_17780 7eeb7033138e0b27810fc5fe6bd1d356 303 SMART SM00062 51 287 7.9E-40 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_17780 7eeb7033138e0b27810fc5fe6bd1d356 303 Gene3D G3DSA:3.40.190.10 138 245 4.3E-68 T 14-10-2018 LH59_17780 7eeb7033138e0b27810fc5fe6bd1d356 303 TIGRFAM TIGR02995 ectoine_ehuB: ectoine/hydroxyectoine ABC transporter solute-binding protein EhuB 29 300 4.1E-93 T 14-10-2018 IPR014337 Ectoine/Hydroxyectoine ABC transporter, substrate-binding protein EhuB GO:0033294|GO:0051470 LH59_17780 7eeb7033138e0b27810fc5fe6bd1d356 303 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 52 281 5.0E-40 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_08005 b1c417845c7e429c7cca4c2718f3fada 232 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 11 185 1.1E-67 T 14-10-2018 IPR022301 Integral membrane protein YjbE LH59_08005 b1c417845c7e429c7cca4c2718f3fada 232 Pfam PF03741 Integral membrane protein TerC family 14 183 2.6E-44 T 14-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 LH59_02000 cf4006087a82c17e662058977fa39787 80 SUPERFAMILY SSF81333 4 77 4.71E-18 T 14-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily LH59_02000 cf4006087a82c17e662058977fa39787 80 Gene3D G3DSA:1.20.20.10 1 76 1.9E-27 T 14-10-2018 IPR038662 F1F0 ATP synthase subunit C superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 LH59_02000 cf4006087a82c17e662058977fa39787 80 Pfam PF00137 ATP synthase subunit C 9 71 2.9E-10 T 14-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 LH59_02000 cf4006087a82c17e662058977fa39787 80 Hamap MF_01396 ATP synthase subunit c [atpH]. 8 73 14.112 T 14-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 LH59_02000 cf4006087a82c17e662058977fa39787 80 ProSitePatterns PS00605 ATP synthase c subunit signature. 38 59 - T 14-10-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 LH59_02000 cf4006087a82c17e662058977fa39787 80 PRINTS PR00124 ATP synthase C subunit signature 10 29 8.9E-5 T 14-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 LH59_02000 cf4006087a82c17e662058977fa39787 80 PRINTS PR00124 ATP synthase C subunit signature 31 46 8.9E-5 T 14-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 LH59_02000 cf4006087a82c17e662058977fa39787 80 PRINTS PR00124 ATP synthase C subunit signature 48 73 8.9E-5 T 14-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 LH59_02000 cf4006087a82c17e662058977fa39787 80 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 19 75 7.9E-22 T 14-10-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 LH59_03260 bee4fe79085ea7ae44f96c43203a3aab 149 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 14-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site LH59_03260 bee4fe79085ea7ae44f96c43203a3aab 149 SMART SM00344 1 109 3.6E-44 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 LH59_03260 bee4fe79085ea7ae44f96c43203a3aab 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 6.1E-15 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_03260 bee4fe79085ea7ae44f96c43203a3aab 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 6.1E-15 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_03260 bee4fe79085ea7ae44f96c43203a3aab 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 6.1E-15 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_03260 bee4fe79085ea7ae44f96c43203a3aab 149 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 48 3.0E-18 T 14-10-2018 LH59_03260 bee4fe79085ea7ae44f96c43203a3aab 149 SUPERFAMILY SSF46785 1 60 8.06E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_03260 bee4fe79085ea7ae44f96c43203a3aab 149 Gene3D G3DSA:1.10.10.10 2 51 1.8E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_03260 bee4fe79085ea7ae44f96c43203a3aab 149 SUPERFAMILY SSF54909 64 149 3.75E-20 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel LH59_03260 bee4fe79085ea7ae44f96c43203a3aab 149 Pfam PF01037 Lrp/AsnC ligand binding domain 67 140 2.3E-23 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LH59_03260 bee4fe79085ea7ae44f96c43203a3aab 149 Gene3D G3DSA:3.30.70.920 52 146 3.9E-22 T 14-10-2018 LH59_20920 a0cac0d2db0d716f2d1d39151304a091 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 300 2.2E-29 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_20920 a0cac0d2db0d716f2d1d39151304a091 301 SUPERFAMILY SSF161098 94 280 1.23E-27 T 14-10-2018 IPR035906 MetI-like superfamily LH59_20920 a0cac0d2db0d716f2d1d39151304a091 301 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 25 58 4.2E-6 T 14-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain LH59_20920 a0cac0d2db0d716f2d1d39151304a091 301 Gene3D G3DSA:1.10.3720.10 87 296 1.2E-25 T 14-10-2018 IPR035906 MetI-like superfamily LH59_05935 af0ad0d6f805d1c4f398b7bc21705f76 303 PIRSF PIRSF016660 1 303 1.1E-117 T 14-10-2018 IPR008526 Inner membrane protein YedI LH59_05935 af0ad0d6f805d1c4f398b7bc21705f76 303 Pfam PF05661 Protein of unknown function (DUF808) 4 292 1.0E-110 T 14-10-2018 IPR008526 Inner membrane protein YedI LH59_15185 d7554ae7e38a2212a2cc3a54d0784521 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 319 8.0E-67 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_15185 d7554ae7e38a2212a2cc3a54d0784521 324 Gene3D G3DSA:3.40.190.10 126 249 6.7E-90 T 14-10-2018 LH59_15185 d7554ae7e38a2212a2cc3a54d0784521 324 PIRSF PIRSF017082 1 323 2.6E-66 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_15185 d7554ae7e38a2212a2cc3a54d0784521 324 Gene3D G3DSA:3.40.190.150 31 313 6.7E-90 T 14-10-2018 LH59_15185 d7554ae7e38a2212a2cc3a54d0784521 324 SUPERFAMILY SSF53850 100 285 1.76E-10 T 14-10-2018 LH59_22170 ab19d900a9d8051db7ddbc532d0273f3 192 SUPERFAMILY SSF52317 1 186 3.01E-49 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_22170 ab19d900a9d8051db7ddbc532d0273f3 192 Pfam PF01965 DJ-1/PfpI family 3 184 1.8E-50 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 LH59_22170 ab19d900a9d8051db7ddbc532d0273f3 192 Gene3D G3DSA:3.40.50.880 1 192 1.6E-52 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_22170 ab19d900a9d8051db7ddbc532d0273f3 192 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 5 186 7.6E-55 T 14-10-2018 IPR006286 Deglycase PfpI LH59_18120 5ed27448b43069c107b974de62e5218d 287 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 152 177 - T 14-10-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 LH59_18120 5ed27448b43069c107b974de62e5218d 287 Gene3D G3DSA:1.10.600.10 4 274 6.0E-88 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily LH59_18120 5ed27448b43069c107b974de62e5218d 287 SUPERFAMILY SSF48576 3 276 9.78E-92 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily LH59_18120 5ed27448b43069c107b974de62e5218d 287 TIGRFAM TIGR03465 HpnD: squalene synthase HpnD 10 275 1.6E-119 T 14-10-2018 IPR017828 Squalene synthase HpnD-like GO:0016117|GO:0016767 LH59_18120 5ed27448b43069c107b974de62e5218d 287 Pfam PF00494 Squalene/phytoene synthase 13 264 5.7E-81 T 14-10-2018 LH59_03275 82e15cd5eff498a86c0ded432795538e 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 7.9E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_03275 82e15cd5eff498a86c0ded432795538e 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 7.9E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_03275 82e15cd5eff498a86c0ded432795538e 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 7.9E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_03275 82e15cd5eff498a86c0ded432795538e 299 Pfam PF03466 LysR substrate binding domain 92 291 4.3E-40 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_03275 82e15cd5eff498a86c0ded432795538e 299 SUPERFAMILY SSF46785 8 115 6.46E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_03275 82e15cd5eff498a86c0ded432795538e 299 SUPERFAMILY SSF53850 93 293 1.45E-39 T 14-10-2018 LH59_03275 82e15cd5eff498a86c0ded432795538e 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 67 1.6E-16 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_03275 82e15cd5eff498a86c0ded432795538e 299 Gene3D G3DSA:3.40.190.290 96 297 2.1E-41 T 14-10-2018 LH59_03275 82e15cd5eff498a86c0ded432795538e 299 Gene3D G3DSA:1.10.10.10 7 93 7.7E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_13555 f0049e7d93ac4538d88df8299b7f21f3 466 Gene3D G3DSA:3.90.226.10 235 411 2.1E-63 T 14-10-2018 LH59_13555 f0049e7d93ac4538d88df8299b7f21f3 466 SUPERFAMILY SSF52096 109 415 8.12E-48 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily LH59_13555 f0049e7d93ac4538d88df8299b7f21f3 466 SUPERFAMILY SSF50156 126 235 2.1E-17 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 LH59_13555 f0049e7d93ac4538d88df8299b7f21f3 466 Gene3D G3DSA:2.30.42.10 147 234 2.1E-63 T 14-10-2018 LH59_13555 f0049e7d93ac4538d88df8299b7f21f3 466 SMART SM00245 220 414 1.3E-28 T 14-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 LH59_13555 f0049e7d93ac4538d88df8299b7f21f3 466 Pfam PF03572 Peptidase family S41 246 412 5.8E-33 T 14-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 LH59_13555 f0049e7d93ac4538d88df8299b7f21f3 466 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 147 207 2.1E-7 T 14-10-2018 IPR001478 PDZ domain GO:0005515 LH59_13555 f0049e7d93ac4538d88df8299b7f21f3 466 SMART SM00228 149 218 6.5E-13 T 14-10-2018 IPR001478 PDZ domain GO:0005515 LH59_13555 f0049e7d93ac4538d88df8299b7f21f3 466 Gene3D G3DSA:3.30.750.44 115 389 2.1E-63 T 14-10-2018 LH59_24205 9db211327c94b1113c9f8a2a159048c0 327 SUPERFAMILY SSF53850 118 289 6.3E-12 T 14-10-2018 LH59_24205 9db211327c94b1113c9f8a2a159048c0 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 323 5.0E-88 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_24205 9db211327c94b1113c9f8a2a159048c0 327 Gene3D G3DSA:3.40.190.150 31 317 8.5E-113 T 14-10-2018 LH59_24205 9db211327c94b1113c9f8a2a159048c0 327 Gene3D G3DSA:3.40.190.10 129 252 8.5E-113 T 14-10-2018 LH59_24205 9db211327c94b1113c9f8a2a159048c0 327 PIRSF PIRSF017082 1 326 1.3E-81 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_01480 aa670094826dfe361c52d20db31f036c 166 Pfam PF05229 Spore Coat Protein U domain 25 163 1.7E-29 T 14-10-2018 IPR007893 Spore coat protein U LH59_01480 aa670094826dfe361c52d20db31f036c 166 SMART SM00972 104 163 4.4E-12 T 14-10-2018 IPR007893 Spore coat protein U LH59_06040 320e55fa806a100a5d4058ef45905a08 1045 Gene3D G3DSA:3.30.70.1430 38 814 0.0 T 14-10-2018 LH59_06040 320e55fa806a100a5d4058ef45905a08 1045 Gene3D G3DSA:3.30.2090.10 718 806 0.0 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_06040 320e55fa806a100a5d4058ef45905a08 1045 Pfam PF00873 AcrB/AcrD/AcrF family 1 1022 0.0 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_06040 320e55fa806a100a5d4058ef45905a08 1045 Gene3D G3DSA:1.20.1640.10 8 511 0.0 T 14-10-2018 LH59_06040 320e55fa806a100a5d4058ef45905a08 1045 SUPERFAMILY SSF82714 182 270 1.22E-18 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_06040 320e55fa806a100a5d4058ef45905a08 1045 SUPERFAMILY SSF82866 295 496 1.31E-49 T 14-10-2018 LH59_06040 320e55fa806a100a5d4058ef45905a08 1045 SUPERFAMILY SSF82714 719 805 6.41E-22 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_06040 320e55fa806a100a5d4058ef45905a08 1045 Gene3D G3DSA:3.30.70.1440 666 862 0.0 T 14-10-2018 LH59_06040 320e55fa806a100a5d4058ef45905a08 1045 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 1 1033 0.0 T 14-10-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0006855|GO:0015562|GO:0016021 LH59_06040 320e55fa806a100a5d4058ef45905a08 1045 SUPERFAMILY SSF82693 38 131 2.88E-25 T 14-10-2018 LH59_06040 320e55fa806a100a5d4058ef45905a08 1045 Gene3D G3DSA:3.30.70.1320 133 331 0.0 T 14-10-2018 LH59_06040 320e55fa806a100a5d4058ef45905a08 1045 Gene3D G3DSA:3.30.2090.10 178 274 0.0 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_06040 320e55fa806a100a5d4058ef45905a08 1045 SUPERFAMILY SSF82866 802 1025 9.81E-42 T 14-10-2018 LH59_06040 320e55fa806a100a5d4058ef45905a08 1045 Gene3D G3DSA:1.20.1640.10 512 1019 0.0 T 14-10-2018 LH59_06040 320e55fa806a100a5d4058ef45905a08 1045 Gene3D G3DSA:3.30.70.1430 566 665 0.0 T 14-10-2018 LH59_06040 320e55fa806a100a5d4058ef45905a08 1045 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 1.7E-104 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_06040 320e55fa806a100a5d4058ef45905a08 1045 PRINTS PR00702 Acriflavin resistance protein family signature 469 492 1.7E-104 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_06040 320e55fa806a100a5d4058ef45905a08 1045 PRINTS PR00702 Acriflavin resistance protein family signature 335 358 1.7E-104 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_06040 320e55fa806a100a5d4058ef45905a08 1045 PRINTS PR00702 Acriflavin resistance protein family signature 551 568 1.7E-104 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_06040 320e55fa806a100a5d4058ef45905a08 1045 PRINTS PR00702 Acriflavin resistance protein family signature 362 383 1.7E-104 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_06040 320e55fa806a100a5d4058ef45905a08 1045 PRINTS PR00702 Acriflavin resistance protein family signature 390 414 1.7E-104 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_06040 320e55fa806a100a5d4058ef45905a08 1045 PRINTS PR00702 Acriflavin resistance protein family signature 444 467 1.7E-104 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_06040 320e55fa806a100a5d4058ef45905a08 1045 PRINTS PR00702 Acriflavin resistance protein family signature 618 632 1.7E-104 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_06040 320e55fa806a100a5d4058ef45905a08 1045 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 1.7E-104 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_06040 320e55fa806a100a5d4058ef45905a08 1045 SUPERFAMILY SSF82693 564 667 5.06E-29 T 14-10-2018 LH59_06040 320e55fa806a100a5d4058ef45905a08 1045 SUPERFAMILY SSF82693 142 329 3.31E-21 T 14-10-2018 LH59_05410 fe9078f49fe8874de28ae59d073b4e3d 230 SUPERFAMILY SSF52172 6 186 1.38E-37 T 14-10-2018 IPR011006 CheY-like superfamily LH59_05410 fe9078f49fe8874de28ae59d073b4e3d 230 SMART SM00862 152 228 2.5E-23 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_05410 fe9078f49fe8874de28ae59d073b4e3d 230 Gene3D G3DSA:1.10.10.10 128 230 6.8E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_05410 fe9078f49fe8874de28ae59d073b4e3d 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 228 1.4E-20 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_05410 fe9078f49fe8874de28ae59d073b4e3d 230 Gene3D G3DSA:3.40.50.2300 2 125 4.6E-34 T 14-10-2018 LH59_05410 fe9078f49fe8874de28ae59d073b4e3d 230 Pfam PF00072 Response regulator receiver domain 8 116 1.5E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_05410 fe9078f49fe8874de28ae59d073b4e3d 230 SMART SM00448 6 116 3.2E-37 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_27905 2ac68f37502901b673b9d1024c496f3a 205 SUPERFAMILY SSF52166 4 205 2.35E-69 T 14-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 LH59_27905 2ac68f37502901b673b9d1024c496f3a 205 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 7 205 31.7 T 14-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_27905 2ac68f37502901b673b9d1024c496f3a 205 Pfam PF00573 Ribosomal protein L4/L1 family 18 202 2.7E-63 T 14-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 LH59_27905 2ac68f37502901b673b9d1024c496f3a 205 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 17 202 1.5E-70 T 14-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_27905 2ac68f37502901b673b9d1024c496f3a 205 Gene3D G3DSA:3.40.1370.10 5 205 5.9E-67 T 14-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 LH59_03930 d438c08f1feae98bc86c1f2d1b7b6adf 158 Pfam PF01037 Lrp/AsnC ligand binding domain 72 149 5.5E-23 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LH59_03930 d438c08f1feae98bc86c1f2d1b7b6adf 158 Gene3D G3DSA:3.30.70.920 59 146 1.4E-25 T 14-10-2018 LH59_03930 d438c08f1feae98bc86c1f2d1b7b6adf 158 Pfam PF13412 Winged helix-turn-helix DNA-binding 6 53 6.9E-22 T 14-10-2018 LH59_03930 d438c08f1feae98bc86c1f2d1b7b6adf 158 SMART SM00344 6 118 3.6E-42 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 LH59_03930 d438c08f1feae98bc86c1f2d1b7b6adf 158 SUPERFAMILY SSF54909 66 157 1.61E-19 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel LH59_03930 d438c08f1feae98bc86c1f2d1b7b6adf 158 Gene3D G3DSA:1.10.10.10 7 58 5.5E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_03930 d438c08f1feae98bc86c1f2d1b7b6adf 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 52 6.6E-18 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_03930 d438c08f1feae98bc86c1f2d1b7b6adf 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 33 6.6E-18 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_03930 d438c08f1feae98bc86c1f2d1b7b6adf 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 22 6.6E-18 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_03930 d438c08f1feae98bc86c1f2d1b7b6adf 158 SUPERFAMILY SSF46785 5 65 1.73E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_16220 482e135eabb7119a50aa8fb1a1700603 324 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 319 2.4E-42 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_16220 482e135eabb7119a50aa8fb1a1700603 324 Gene3D G3DSA:1.10.3720.10 83 315 3.3E-25 T 14-10-2018 IPR035906 MetI-like superfamily LH59_16220 482e135eabb7119a50aa8fb1a1700603 324 SUPERFAMILY SSF161098 90 306 1.7E-21 T 14-10-2018 IPR035906 MetI-like superfamily LH59_12635 38ad57acca6f0a4427aaed441adec93e 67 Gene3D G3DSA:3.90.940.10 1 67 3.8E-19 T 14-10-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 LH59_12635 38ad57acca6f0a4427aaed441adec93e 67 SMART SM01409 8 59 5.5E-12 T 14-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 LH59_12635 38ad57acca6f0a4427aaed441adec93e 67 SUPERFAMILY SSF63562 1 63 1.4E-18 T 14-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 LH59_12635 38ad57acca6f0a4427aaed441adec93e 67 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 56 8.5E-16 T 14-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LH59_12635 38ad57acca6f0a4427aaed441adec93e 67 Pfam PF01192 RNA polymerase Rpb6 8 56 7.4E-13 T 14-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 LH59_12635 38ad57acca6f0a4427aaed441adec93e 67 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 60 15.649 T 14-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LH59_27000 7bed1327b0b20804bf9214781ec29c01 591 Gene3D G3DSA:3.40.50.300 1 211 1.6E-77 T 14-10-2018 LH59_27000 7bed1327b0b20804bf9214781ec29c01 591 SUPERFAMILY SSF52540 73 361 9.64E-72 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_27000 7bed1327b0b20804bf9214781ec29c01 591 Gene3D G3DSA:3.40.50.300 213 381 5.9E-51 T 14-10-2018 LH59_27000 7bed1327b0b20804bf9214781ec29c01 591 SMART SM00490 259 340 4.3E-31 T 14-10-2018 IPR001650 Helicase, C-terminal LH59_27000 7bed1327b0b20804bf9214781ec29c01 591 Pfam PF00271 Helicase conserved C-terminal domain 235 340 4.9E-27 T 14-10-2018 IPR001650 Helicase, C-terminal LH59_27000 7bed1327b0b20804bf9214781ec29c01 591 Pfam PF00270 DEAD/DEAH box helicase 25 195 3.1E-48 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 LH59_27000 7bed1327b0b20804bf9214781ec29c01 591 SMART SM00487 20 222 6.1E-57 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain LH59_27000 7bed1327b0b20804bf9214781ec29c01 591 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 153 161 - T 14-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site LH59_23245 8429df4f67983ba7b3f9ccf626d5ae80 303 Gene3D G3DSA:3.40.190.10 165 266 2.5E-48 T 14-10-2018 LH59_23245 8429df4f67983ba7b3f9ccf626d5ae80 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 65 8.4E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_23245 8429df4f67983ba7b3f9ccf626d5ae80 303 Gene3D G3DSA:1.10.10.10 5 92 4.4E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_23245 8429df4f67983ba7b3f9ccf626d5ae80 303 Gene3D G3DSA:3.40.190.10 93 293 2.5E-48 T 14-10-2018 LH59_23245 8429df4f67983ba7b3f9ccf626d5ae80 303 SUPERFAMILY SSF53850 90 299 1.45E-35 T 14-10-2018 LH59_23245 8429df4f67983ba7b3f9ccf626d5ae80 303 Pfam PF03466 LysR substrate binding domain 90 296 7.1E-36 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_23245 8429df4f67983ba7b3f9ccf626d5ae80 303 SUPERFAMILY SSF46785 9 114 7.27E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_27305 c0025c5c8f92551d59fb802ab7b03f18 366 Gene3D G3DSA:3.90.1150.10 237 365 6.4E-36 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_27305 c0025c5c8f92551d59fb802ab7b03f18 366 SUPERFAMILY SSF53383 9 365 1.06E-116 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_27305 c0025c5c8f92551d59fb802ab7b03f18 366 PIRSF PIRSF000390 2 366 3.9E-109 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase LH59_27305 c0025c5c8f92551d59fb802ab7b03f18 366 Gene3D G3DSA:3.40.640.10 1 236 7.6E-95 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_27305 c0025c5c8f92551d59fb802ab7b03f18 366 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 17 362 1.9E-130 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase LH59_15225 c824ed2cf097545a1e6c05d9a25984dd 507 Pfam PF01936 NYN domain 10 153 9.8E-33 T 14-10-2018 IPR021139 NYN domain, limkain-b1-type LH59_15225 c824ed2cf097545a1e6c05d9a25984dd 507 Gene3D G3DSA:3.40.50.1010 2 157 4.7E-36 T 14-10-2018 LH59_17010 9a13f2e71b8e62610470fc07d8f89c8f 252 Gene3D G3DSA:3.40.50.300 1 250 5.4E-70 T 14-10-2018 LH59_17010 9a13f2e71b8e62610470fc07d8f89c8f 252 SUPERFAMILY SSF52540 2 225 1.66E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_17010 9a13f2e71b8e62610470fc07d8f89c8f 252 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_17010 9a13f2e71b8e62610470fc07d8f89c8f 252 SMART SM00382 26 213 9.3E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_17010 9a13f2e71b8e62610470fc07d8f89c8f 252 Pfam PF00005 ABC transporter 18 164 8.8E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_05885 b715e52739b67257673fcd6561714eb9 254 SUPERFAMILY SSF51735 1 251 7.09E-79 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_05885 b715e52739b67257673fcd6561714eb9 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 6.7E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_05885 b715e52739b67257673fcd6561714eb9 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 6.7E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_05885 b715e52739b67257673fcd6561714eb9 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 250 2.2E-66 T 14-10-2018 LH59_05885 b715e52739b67257673fcd6561714eb9 254 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 190 0.0038 T 14-10-2018 LH59_05885 b715e52739b67257673fcd6561714eb9 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 7.2E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_05885 b715e52739b67257673fcd6561714eb9 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 7.2E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_05885 b715e52739b67257673fcd6561714eb9 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 7.2E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_05885 b715e52739b67257673fcd6561714eb9 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 7.2E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_05885 b715e52739b67257673fcd6561714eb9 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 7.2E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_05885 b715e52739b67257673fcd6561714eb9 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 7.2E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_05885 b715e52739b67257673fcd6561714eb9 254 Gene3D G3DSA:3.40.50.720 1 252 8.8E-83 T 14-10-2018 LH59_06220 060c9affc855096760b0cfdf8ae4ab55 464 Pfam PF00512 His Kinase A (phospho-acceptor) domain 240 293 1.2E-6 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_06220 060c9affc855096760b0cfdf8ae4ab55 464 Gene3D G3DSA:3.30.450.300 36 162 1.6E-45 T 14-10-2018 IPR038421 Sensor histidine kinase RisS, periplasmic domain superfamily LH59_06220 060c9affc855096760b0cfdf8ae4ab55 464 SMART SM00388 238 297 1.8E-6 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_06220 060c9affc855096760b0cfdf8ae4ab55 464 SUPERFAMILY SSF158472 187 234 1.07E-5 T 14-10-2018 LH59_06220 060c9affc855096760b0cfdf8ae4ab55 464 SUPERFAMILY SSF55874 296 454 7.07E-30 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_06220 060c9affc855096760b0cfdf8ae4ab55 464 PRINTS PR00344 Bacterial sensor protein C-terminal signature 397 407 9.1E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_06220 060c9affc855096760b0cfdf8ae4ab55 464 PRINTS PR00344 Bacterial sensor protein C-terminal signature 379 393 9.1E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_06220 060c9affc855096760b0cfdf8ae4ab55 464 PRINTS PR00344 Bacterial sensor protein C-terminal signature 437 450 9.1E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_06220 060c9affc855096760b0cfdf8ae4ab55 464 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 431 9.1E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_06220 060c9affc855096760b0cfdf8ae4ab55 464 SMART SM00387 339 453 8.2E-24 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_06220 060c9affc855096760b0cfdf8ae4ab55 464 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 343 452 5.9E-18 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_06220 060c9affc855096760b0cfdf8ae4ab55 464 SUPERFAMILY SSF47384 222 293 9.61E-11 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 LH59_06220 060c9affc855096760b0cfdf8ae4ab55 464 Pfam PF16524 Periplasmic domain of Sensor histidine kinase RisS 51 157 1.2E-38 T 14-10-2018 IPR032408 Sensor histidine kinase RisS, periplasmic domain LH59_06220 060c9affc855096760b0cfdf8ae4ab55 464 SMART SM00304 185 237 4.4E-12 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_06220 060c9affc855096760b0cfdf8ae4ab55 464 Gene3D G3DSA:3.30.565.10 298 456 1.3E-28 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_06220 060c9affc855096760b0cfdf8ae4ab55 464 Gene3D G3DSA:1.10.287.130 186 292 4.1E-20 T 14-10-2018 LH59_06220 060c9affc855096760b0cfdf8ae4ab55 464 Pfam PF00672 HAMP domain 187 233 9.0E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_03180 d73fb181a209d17f3ecbbabc08e5a8bb 448 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 1.1E-45 T 14-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LH59_03180 d73fb181a209d17f3ecbbabc08e5a8bb 448 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 154 168 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 LH59_03180 d73fb181a209d17f3ecbbabc08e5a8bb 448 SUPERFAMILY SSF51246 331 443 1.52E-43 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 LH59_03180 d73fb181a209d17f3ecbbabc08e5a8bb 448 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 445 3.4E-222 T 14-10-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 LH59_03180 d73fb181a209d17f3ecbbabc08e5a8bb 448 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 LH59_03180 d73fb181a209d17f3ecbbabc08e5a8bb 448 Gene3D G3DSA:3.30.470.20 87 433 1.1E-150 T 14-10-2018 LH59_03180 d73fb181a209d17f3ecbbabc08e5a8bb 448 Gene3D G3DSA:3.40.50.20 1 85 1.4E-34 T 14-10-2018 LH59_03180 d73fb181a209d17f3ecbbabc08e5a8bb 448 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 321 4.5E-78 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 LH59_03180 d73fb181a209d17f3ecbbabc08e5a8bb 448 Pfam PF02785 Biotin carboxylase C-terminal domain 336 441 7.5E-39 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LH59_03180 d73fb181a209d17f3ecbbabc08e5a8bb 448 SMART SM00878 336 441 9.7E-65 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LH59_03180 d73fb181a209d17f3ecbbabc08e5a8bb 448 SUPERFAMILY SSF56059 83 347 7.78E-71 T 14-10-2018 LH59_03180 d73fb181a209d17f3ecbbabc08e5a8bb 448 Gene3D G3DSA:3.30.1490.20 131 203 1.1E-150 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 LH59_03180 d73fb181a209d17f3ecbbabc08e5a8bb 448 SUPERFAMILY SSF52440 1 113 2.66E-48 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily LH59_14995 f34040e94d21413ef627dbd9b1f9bad3 489 Pfam PF00817 impB/mucB/samB family 24 146 2.5E-6 T 14-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 LH59_14995 f34040e94d21413ef627dbd9b1f9bad3 489 Gene3D G3DSA:2.30.40.20 29 68 4.0E-10 T 14-10-2018 LH59_14995 f34040e94d21413ef627dbd9b1f9bad3 489 SUPERFAMILY SSF56672 4 226 4.78E-29 T 14-10-2018 LH59_14995 f34040e94d21413ef627dbd9b1f9bad3 489 Gene3D G3DSA:3.30.70.270 69 169 4.0E-10 T 14-10-2018 LH59_14995 f34040e94d21413ef627dbd9b1f9bad3 489 Gene3D G3DSA:1.10.150.20 170 217 4.0E-10 T 14-10-2018 LH59_08365 3b3ef73cc0186126a3c25c8a5af09246 340 Gene3D G3DSA:1.10.150.130 12 121 1.5E-5 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal LH59_08365 3b3ef73cc0186126a3c25c8a5af09246 340 Pfam PF00589 Phage integrase family 140 303 1.6E-16 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 LH59_08365 3b3ef73cc0186126a3c25c8a5af09246 340 Gene3D G3DSA:1.10.443.10 136 318 7.1E-24 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 LH59_08365 3b3ef73cc0186126a3c25c8a5af09246 340 SUPERFAMILY SSF56349 15 309 1.18E-35 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 LH59_06780 3c0fade69faac5ec0860b9cd7f43d4b4 596 SUPERFAMILY SSF55920 305 562 8.24E-53 T 14-10-2018 IPR036005 Creatinase/aminopeptidase-like LH59_06780 3c0fade69faac5ec0860b9cd7f43d4b4 596 Pfam PF00557 Metallopeptidase family M24 311 524 7.5E-43 T 14-10-2018 IPR000994 Peptidase M24 LH59_06780 3c0fade69faac5ec0860b9cd7f43d4b4 596 SUPERFAMILY SSF53092 172 299 5.75E-7 T 14-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal LH59_06780 3c0fade69faac5ec0860b9cd7f43d4b4 596 Pfam PF16189 Creatinase/Prolidase N-terminal domain 151 308 3.4E-35 T 14-10-2018 LH59_06780 3c0fade69faac5ec0860b9cd7f43d4b4 596 SUPERFAMILY SSF53092 5 130 5.58E-11 T 14-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal LH59_06780 3c0fade69faac5ec0860b9cd7f43d4b4 596 Gene3D G3DSA:3.40.350.10 149 291 2.8E-31 T 14-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal LH59_06780 3c0fade69faac5ec0860b9cd7f43d4b4 596 Gene3D G3DSA:3.40.350.10 1 148 2.0E-42 T 14-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal LH59_06780 3c0fade69faac5ec0860b9cd7f43d4b4 596 Pfam PF16188 C-terminal region of peptidase_M24 536 596 2.5E-25 T 14-10-2018 IPR032416 Peptidase M24, C-terminal domain LH59_06780 3c0fade69faac5ec0860b9cd7f43d4b4 596 Gene3D G3DSA:3.90.230.10 303 596 4.6E-93 T 14-10-2018 LH59_06780 3c0fade69faac5ec0860b9cd7f43d4b4 596 Pfam PF01321 Creatinase/Prolidase N-terminal domain 7 133 1.6E-17 T 14-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 LH59_26530 dfc00fa7ed55e5532372904fe96fbfbd 239 Gene3D G3DSA:3.20.20.10 1 238 2.3E-88 T 14-10-2018 IPR029066 PLP-binding barrel LH59_26530 dfc00fa7ed55e5532372904fe96fbfbd 239 Pfam PF01168 Alanine racemase, N-terminal domain 9 233 3.6E-25 T 14-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LH59_26530 dfc00fa7ed55e5532372904fe96fbfbd 239 SUPERFAMILY SSF51419 4 231 3.66E-73 T 14-10-2018 IPR029066 PLP-binding barrel LH59_26530 dfc00fa7ed55e5532372904fe96fbfbd 239 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 8 233 1.7E-55 T 14-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 LH59_26530 dfc00fa7ed55e5532372904fe96fbfbd 239 Hamap MF_02087 Pyridoxal phosphate homeostasis protein. 9 232 28.932 T 14-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 LH59_26530 dfc00fa7ed55e5532372904fe96fbfbd 239 PIRSF PIRSF004848 1 239 1.7E-73 T 14-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 LH59_24915 37820242f225db4846d102ff72113c34 176 Pfam PF03724 META domain 46 167 1.0E-22 T 14-10-2018 IPR005184 Domain of unknown function DUF306, Meta/HslJ LH59_24915 37820242f225db4846d102ff72113c34 176 Gene3D G3DSA:2.40.128.270 43 172 3.1E-34 T 14-10-2018 IPR038670 HslJ-like superfamily LH59_13640 da54e4e604b760af5afc31da1bb2d5e2 481 Pfam PF07364 Metallopeptidase family M81 2 288 2.1E-89 T 14-10-2018 IPR015995 Microcystin LR degradation protein MlrC, N-terminal LH59_13640 da54e4e604b760af5afc31da1bb2d5e2 481 Pfam PF07171 MlrC C-terminus 297 471 6.4E-51 T 14-10-2018 IPR010799 Microcystin LR degradation protein MlrC, C-terminal LH59_13640 da54e4e604b760af5afc31da1bb2d5e2 481 PIRSF PIRSF012702 1 481 1.8E-168 T 14-10-2018 IPR009197 Microcystin LR degradation protein MlrC LH59_07075 05352d726da303577765259d3cc99344 178 Pfam PF10634 Fe2+ transport protein 20 171 1.9E-70 T 14-10-2018 IPR018470 Periplasmic metal-binding protein Tp34-type LH59_07075 05352d726da303577765259d3cc99344 178 Gene3D G3DSA:2.60.40.2480 19 178 2.3E-72 T 14-10-2018 IPR038482 Periplasmic metal-binding protein tp34-type superfamily LH59_07075 05352d726da303577765259d3cc99344 178 PIRSF PIRSF017018 1 178 1.8E-86 T 14-10-2018 IPR018470 Periplasmic metal-binding protein Tp34-type LH59_26490 5dd5c5fd0342023fea0eba8e63c774a6 171 Pfam PF01928 CYTH domain 3 163 1.6E-17 T 14-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 LH59_26490 5dd5c5fd0342023fea0eba8e63c774a6 171 Gene3D G3DSA:2.40.320.10 1 170 2.1E-33 T 14-10-2018 LH59_26490 5dd5c5fd0342023fea0eba8e63c774a6 171 SMART SM01118 2 169 9.6E-17 T 14-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 LH59_26490 5dd5c5fd0342023fea0eba8e63c774a6 171 SUPERFAMILY SSF55154 3 167 8.99E-35 T 14-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 LH59_22540 9fbf1181900ee9a88d42e65c7643bc34 109 Gene3D G3DSA:2.60.120.10 5 109 9.0E-8 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_22540 9fbf1181900ee9a88d42e65c7643bc34 109 SUPERFAMILY SSF51182 28 107 6.97E-11 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_03835 fc48428efd418b3aa9f22f432808b960 228 Gene3D G3DSA:3.40.50.2300 1 118 7.4E-35 T 14-10-2018 LH59_03835 fc48428efd418b3aa9f22f432808b960 228 Pfam PF00072 Response regulator receiver domain 3 112 7.6E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_03835 fc48428efd418b3aa9f22f432808b960 228 SMART SM00862 145 218 5.1E-13 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_03835 fc48428efd418b3aa9f22f432808b960 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 218 1.3E-14 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_03835 fc48428efd418b3aa9f22f432808b960 228 Gene3D G3DSA:1.10.10.10 119 225 4.8E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_03835 fc48428efd418b3aa9f22f432808b960 228 SMART SM00448 1 112 7.4E-33 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_03835 fc48428efd418b3aa9f22f432808b960 228 SUPERFAMILY SSF52172 1 174 1.15E-36 T 14-10-2018 IPR011006 CheY-like superfamily LH59_24505 0ec680c3b9c8315c2429d2bbb10df249 537 Pfam PF00005 ABC transporter 34 171 4.3E-17 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_24505 0ec680c3b9c8315c2429d2bbb10df249 537 SUPERFAMILY SSF52540 356 519 1.8E-31 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_24505 0ec680c3b9c8315c2429d2bbb10df249 537 Gene3D G3DSA:3.40.50.300 4 278 3.6E-45 T 14-10-2018 LH59_24505 0ec680c3b9c8315c2429d2bbb10df249 537 SMART SM00382 30 216 6.6E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_24505 0ec680c3b9c8315c2429d2bbb10df249 537 SMART SM00382 364 531 3.2E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_24505 0ec680c3b9c8315c2429d2bbb10df249 537 SUPERFAMILY SSF52540 19 212 5.17E-36 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_24505 0ec680c3b9c8315c2429d2bbb10df249 537 Gene3D G3DSA:3.40.50.300 300 531 1.6E-37 T 14-10-2018 LH59_24505 0ec680c3b9c8315c2429d2bbb10df249 537 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_24505 0ec680c3b9c8315c2429d2bbb10df249 537 Pfam PF00005 ABC transporter 357 484 3.8E-17 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_02920 28407048c768de04357984ee7b837fe4 125 Pfam PF09345 Domain of unknown function (DUF1987) 6 122 1.5E-38 T 14-10-2018 IPR018530 Domain of unknown function DUF1987 LH59_19925 ee565e5f6ec4bf028506c0d425bb6cdf 315 Gene3D G3DSA:2.160.10.10 197 307 2.3E-30 T 14-10-2018 LH59_19925 ee565e5f6ec4bf028506c0d425bb6cdf 315 Gene3D G3DSA:1.10.3130.10 42 196 3.8E-45 T 14-10-2018 LH59_19925 ee565e5f6ec4bf028506c0d425bb6cdf 315 SUPERFAMILY SSF51161 111 299 1.05E-44 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily LH59_19925 ee565e5f6ec4bf028506c0d425bb6cdf 315 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 257 290 3.5E-7 T 14-10-2018 IPR001451 Hexapeptide repeat LH59_19925 ee565e5f6ec4bf028506c0d425bb6cdf 315 PIRSF PIRSF000441 130 303 4.6E-51 T 14-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 LH59_16530 00e05cd07c90c7fad85e29af3a6f1e72 330 PIRSF PIRSF017082 3 325 8.0E-74 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_16530 00e05cd07c90c7fad85e29af3a6f1e72 330 Gene3D G3DSA:3.40.190.150 31 316 1.4E-98 T 14-10-2018 LH59_16530 00e05cd07c90c7fad85e29af3a6f1e72 330 Gene3D G3DSA:3.40.190.10 128 251 1.4E-98 T 14-10-2018 LH59_16530 00e05cd07c90c7fad85e29af3a6f1e72 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 322 1.3E-70 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_16530 00e05cd07c90c7fad85e29af3a6f1e72 330 SUPERFAMILY SSF53850 117 281 7.6E-7 T 14-10-2018 LH59_00020 809e246c1ab034c1c469442c17e34699 307 SUPERFAMILY SSF46785 5 115 1.7E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_00020 809e246c1ab034c1c469442c17e34699 307 Gene3D G3DSA:1.10.10.10 6 92 2.6E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_00020 809e246c1ab034c1c469442c17e34699 307 Gene3D G3DSA:3.40.190.290 94 296 9.1E-62 T 14-10-2018 LH59_00020 809e246c1ab034c1c469442c17e34699 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 65 2.4E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_00020 809e246c1ab034c1c469442c17e34699 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 4.5E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_00020 809e246c1ab034c1c469442c17e34699 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 4.5E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_00020 809e246c1ab034c1c469442c17e34699 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 4.5E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_00020 809e246c1ab034c1c469442c17e34699 307 SUPERFAMILY SSF53850 93 300 6.7E-45 T 14-10-2018 LH59_00020 809e246c1ab034c1c469442c17e34699 307 Pfam PF03466 LysR substrate binding domain 92 296 4.0E-43 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_20205 f119b1bd4744cc899576eb827ae9d27a 210 SUPERFAMILY SSF46689 16 89 3.74E-20 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_20205 f119b1bd4744cc899576eb827ae9d27a 210 ProSitePatterns PS01081 TetR-type HTH domain signature. 40 71 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site LH59_20205 f119b1bd4744cc899576eb827ae9d27a 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 41 4.6E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_20205 f119b1bd4744cc899576eb827ae9d27a 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 49 72 4.6E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_20205 f119b1bd4744cc899576eb827ae9d27a 210 Gene3D G3DSA:1.10.357.10 17 210 7.3E-35 T 14-10-2018 LH59_20205 f119b1bd4744cc899576eb827ae9d27a 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 74 1.6E-16 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_20205 f119b1bd4744cc899576eb827ae9d27a 210 SUPERFAMILY SSF48498 97 205 1.14E-6 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily LH59_17930 160cc058373a0679128cb51b8dd021bc 1091 Gene3D G3DSA:1.25.40.20 77 293 5.0E-8 T 14-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily LH59_17930 160cc058373a0679128cb51b8dd021bc 1091 SMART SM00248 783 812 3.1 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 LH59_17930 160cc058373a0679128cb51b8dd021bc 1091 SMART SM00248 192 221 11.0 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 LH59_17930 160cc058373a0679128cb51b8dd021bc 1091 SMART SM00248 453 482 0.09 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 LH59_17930 160cc058373a0679128cb51b8dd021bc 1091 SMART SM00248 816 845 120.0 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 LH59_17930 160cc058373a0679128cb51b8dd021bc 1091 SMART SM00248 600 629 1.8 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 LH59_17930 160cc058373a0679128cb51b8dd021bc 1091 SMART SM00248 418 447 1600.0 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 LH59_17930 160cc058373a0679128cb51b8dd021bc 1091 SMART SM00248 330 361 100.0 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 LH59_17930 160cc058373a0679128cb51b8dd021bc 1091 SMART SM00248 633 662 0.0062 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 LH59_17930 160cc058373a0679128cb51b8dd021bc 1091 SUPERFAMILY SSF48403 543 841 8.83E-25 T 14-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily LH59_17930 160cc058373a0679128cb51b8dd021bc 1091 Gene3D G3DSA:1.25.40.20 307 670 6.4E-36 T 14-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily LH59_17930 160cc058373a0679128cb51b8dd021bc 1091 Gene3D G3DSA:1.25.40.20 744 843 1.3E-14 T 14-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily LH59_17930 160cc058373a0679128cb51b8dd021bc 1091 SUPERFAMILY SSF48403 187 509 6.87E-16 T 14-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily LH59_01315 893b50a9d1e8cd2039b180c130564fcc 518 Pfam PF02910 Fumarate reductase flavoprotein C-term 421 503 1.4E-12 T 14-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 LH59_01315 893b50a9d1e8cd2039b180c130564fcc 518 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 339 361 6.7E-10 T 14-10-2018 LH59_01315 893b50a9d1e8cd2039b180c130564fcc 518 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 6.7E-10 T 14-10-2018 LH59_01315 893b50a9d1e8cd2039b180c130564fcc 518 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 182 200 6.7E-10 T 14-10-2018 LH59_01315 893b50a9d1e8cd2039b180c130564fcc 518 Gene3D G3DSA:1.20.58.100 409 516 2.7E-20 T 14-10-2018 LH59_01315 893b50a9d1e8cd2039b180c130564fcc 518 SUPERFAMILY SSF46977 420 504 3.14E-19 T 14-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 LH59_01315 893b50a9d1e8cd2039b180c130564fcc 518 Gene3D G3DSA:3.90.700.10 232 342 3.4E-144 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 LH59_01315 893b50a9d1e8cd2039b180c130564fcc 518 Gene3D G3DSA:3.50.50.60 4 388 3.4E-144 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_01315 893b50a9d1e8cd2039b180c130564fcc 518 Pfam PF00890 FAD binding domain 4 376 6.9E-93 T 14-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 LH59_01315 893b50a9d1e8cd2039b180c130564fcc 518 SUPERFAMILY SSF51905 2 397 1.8E-59 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_01315 893b50a9d1e8cd2039b180c130564fcc 518 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 2 500 5.3E-165 T 14-10-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 LH59_01315 893b50a9d1e8cd2039b180c130564fcc 518 SUPERFAMILY SSF56425 223 337 8.82E-39 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 LH59_19435 4801f446775138d5ff0bae2756e226ad 168 SUPERFAMILY SSF142433 2 159 1.7E-40 T 14-10-2018 IPR036653 CinA-like, C-terminal LH59_19435 4801f446775138d5ff0bae2756e226ad 168 Gene3D G3DSA:3.90.950.20 1 160 3.1E-45 T 14-10-2018 IPR036653 CinA-like, C-terminal LH59_19435 4801f446775138d5ff0bae2756e226ad 168 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 11 155 9.4E-27 T 14-10-2018 IPR008136 CinA, C-terminal LH59_19435 4801f446775138d5ff0bae2756e226ad 168 Pfam PF02464 Competence-damaged protein 5 157 9.7E-38 T 14-10-2018 IPR008136 CinA, C-terminal LH59_20260 f05e6a033a0956c65a3648af657e99d2 241 Gene3D G3DSA:1.10.760.10 33 115 2.1E-19 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_20260 f05e6a033a0956c65a3648af657e99d2 241 Gene3D G3DSA:1.10.760.10 128 222 2.2E-22 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_20260 f05e6a033a0956c65a3648af657e99d2 241 SUPERFAMILY SSF46626 133 221 2.36E-20 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_20260 f05e6a033a0956c65a3648af657e99d2 241 Pfam PF00034 Cytochrome c 153 218 1.1E-5 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_20260 f05e6a033a0956c65a3648af657e99d2 241 SUPERFAMILY SSF46626 47 118 1.24E-17 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_20260 f05e6a033a0956c65a3648af657e99d2 241 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 48 111 3.8E-5 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_20260 f05e6a033a0956c65a3648af657e99d2 241 PIRSF PIRSF000005 7 224 4.9E-58 T 14-10-2018 IPR024167 Cytochrome c4-like GO:0005506|GO:0009055|GO:0020037|GO:0042597 LH59_24630 16c50ca9cbbbb709509bddc25f7c2220 325 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 32 308 2.4E-91 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 LH59_24630 16c50ca9cbbbb709509bddc25f7c2220 325 SUPERFAMILY SSF53850 137 273 1.9E-5 T 14-10-2018 LH59_24630 16c50ca9cbbbb709509bddc25f7c2220 325 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 35 284 8.9E-73 T 14-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 LH59_24630 16c50ca9cbbbb709509bddc25f7c2220 325 PIRSF PIRSF006470 2 325 6.2E-97 T 14-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 LH59_24630 16c50ca9cbbbb709509bddc25f7c2220 325 Gene3D G3DSA:3.40.190.170 27 325 9.6E-117 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily LH59_09350 f989371d05b83d1ebda2835545746889 478 SMART SM00387 352 466 8.8E-25 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_09350 f989371d05b83d1ebda2835545746889 478 SUPERFAMILY SSF47384 234 307 1.04E-11 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 LH59_09350 f989371d05b83d1ebda2835545746889 478 Pfam PF00512 His Kinase A (phospho-acceptor) domain 243 307 2.1E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_09350 f989371d05b83d1ebda2835545746889 478 PRINTS PR00344 Bacterial sensor protein C-terminal signature 393 407 3.1E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_09350 f989371d05b83d1ebda2835545746889 478 PRINTS PR00344 Bacterial sensor protein C-terminal signature 411 421 3.1E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_09350 f989371d05b83d1ebda2835545746889 478 PRINTS PR00344 Bacterial sensor protein C-terminal signature 426 444 3.1E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_09350 f989371d05b83d1ebda2835545746889 478 PRINTS PR00344 Bacterial sensor protein C-terminal signature 450 463 3.1E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_09350 f989371d05b83d1ebda2835545746889 478 SMART SM00388 242 309 6.6E-8 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_09350 f989371d05b83d1ebda2835545746889 478 SUPERFAMILY SSF55874 299 464 1.31E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_09350 f989371d05b83d1ebda2835545746889 478 Gene3D G3DSA:3.30.565.10 315 470 1.7E-33 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_09350 f989371d05b83d1ebda2835545746889 478 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 360 464 7.8E-18 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_09350 f989371d05b83d1ebda2835545746889 478 Gene3D G3DSA:1.10.287.130 231 309 1.1E-10 T 14-10-2018 LH59_10750 e2ebae9ac3793c9de4f6ad61281df189 630 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 216 624 1.5E-93 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit LH59_10750 e2ebae9ac3793c9de4f6ad61281df189 630 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 225 626 8.9E-86 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 LH59_10750 e2ebae9ac3793c9de4f6ad61281df189 630 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 49 176 3.7E-28 T 14-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ LH59_21150 7c1c46ea3a9ecd1dbd5b14ba696e76e1 259 Gene3D G3DSA:2.60.120.10 1 86 3.1E-6 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_21150 7c1c46ea3a9ecd1dbd5b14ba696e76e1 259 SUPERFAMILY SSF46689 213 255 3.67E-7 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_21150 7c1c46ea3a9ecd1dbd5b14ba696e76e1 259 Gene3D G3DSA:1.10.10.60 156 216 2.9E-9 T 14-10-2018 LH59_21150 7c1c46ea3a9ecd1dbd5b14ba696e76e1 259 Pfam PF12833 Helix-turn-helix domain 179 256 5.8E-20 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_21150 7c1c46ea3a9ecd1dbd5b14ba696e76e1 259 SMART SM00342 173 255 4.6E-19 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_21150 7c1c46ea3a9ecd1dbd5b14ba696e76e1 259 Gene3D G3DSA:1.10.10.60 217 259 1.1E-7 T 14-10-2018 LH59_21150 7c1c46ea3a9ecd1dbd5b14ba696e76e1 259 SUPERFAMILY SSF51182 12 202 3.02E-13 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_21150 7c1c46ea3a9ecd1dbd5b14ba696e76e1 259 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 239 255 4.3E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 LH59_21150 7c1c46ea3a9ecd1dbd5b14ba696e76e1 259 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 224 239 4.3E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 LH59_21150 7c1c46ea3a9ecd1dbd5b14ba696e76e1 259 Pfam PF02311 AraC-like ligand binding domain 26 108 2.1E-4 T 14-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 LH59_02255 1313dd226c4fa36d0c6d74af15da74d0 303 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 90 301 4.4E-68 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 LH59_02255 1313dd226c4fa36d0c6d74af15da74d0 303 SUPERFAMILY SSF56529 78 302 1.44E-71 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 LH59_02255 1313dd226c4fa36d0c6d74af15da74d0 303 Gene3D G3DSA:3.90.850.10 84 303 7.5E-80 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 LH59_08590 9e34fded0c4cedb87b002c7d86679f36 393 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 212 249 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LH59_08590 9e34fded0c4cedb87b002c7d86679f36 393 Pfam PF00202 Aminotransferase class-III 12 382 9.5E-110 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LH59_08590 9e34fded0c4cedb87b002c7d86679f36 393 PIRSF PIRSF000521 161 388 3.2E-31 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LH59_08590 9e34fded0c4cedb87b002c7d86679f36 393 PIRSF PIRSF000521 5 150 1.1E-11 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LH59_08590 9e34fded0c4cedb87b002c7d86679f36 393 Gene3D G3DSA:3.40.640.10 48 294 4.2E-137 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_08590 9e34fded0c4cedb87b002c7d86679f36 393 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 4 388 70.248 T 14-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 LH59_08590 9e34fded0c4cedb87b002c7d86679f36 393 Gene3D G3DSA:3.90.1150.10 13 375 4.2E-137 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_08590 9e34fded0c4cedb87b002c7d86679f36 393 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 7 383 2.2E-134 T 14-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 LH59_08590 9e34fded0c4cedb87b002c7d86679f36 393 SUPERFAMILY SSF53383 5 385 4.03E-123 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_11905 7e97619cccefb84d05944185dc53cf40 164 Gene3D G3DSA:3.40.30.10 1 163 1.5E-69 T 14-10-2018 LH59_11905 7e97619cccefb84d05944185dc53cf40 164 PIRSF PIRSF000303 1 162 1.0E-64 T 14-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 LH59_11905 7e97619cccefb84d05944185dc53cf40 164 Pfam PF00255 Glutathione peroxidase 4 111 3.7E-43 T 14-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 LH59_11905 7e97619cccefb84d05944185dc53cf40 164 ProSitePatterns PS00460 Glutathione peroxidases active site. 24 39 - T 14-10-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 LH59_11905 7e97619cccefb84d05944185dc53cf40 164 PRINTS PR01011 Glutathione peroxidase family signature 22 39 3.7E-21 T 14-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 LH59_11905 7e97619cccefb84d05944185dc53cf40 164 PRINTS PR01011 Glutathione peroxidase family signature 57 73 3.7E-21 T 14-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 LH59_11905 7e97619cccefb84d05944185dc53cf40 164 PRINTS PR01011 Glutathione peroxidase family signature 123 132 3.7E-21 T 14-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 LH59_11905 7e97619cccefb84d05944185dc53cf40 164 SUPERFAMILY SSF52833 3 159 1.44E-61 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_10760 c13a595f3942ed5897ad8c1ad8e05f4b 275 SMART SM00346 11 102 1.8E-10 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_10760 c13a595f3942ed5897ad8c1ad8e05f4b 275 Gene3D G3DSA:3.30.450.40 80 260 1.1E-33 T 14-10-2018 IPR029016 GAF-like domain superfamily LH59_10760 c13a595f3942ed5897ad8c1ad8e05f4b 275 Gene3D G3DSA:1.10.10.10 11 74 1.5E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_10760 c13a595f3942ed5897ad8c1ad8e05f4b 275 SUPERFAMILY SSF55781 78 253 1.49E-36 T 14-10-2018 LH59_10760 c13a595f3942ed5897ad8c1ad8e05f4b 275 Pfam PF09339 IclR helix-turn-helix domain 13 64 4.5E-12 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_10760 c13a595f3942ed5897ad8c1ad8e05f4b 275 SUPERFAMILY SSF46785 12 86 1.24E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_10760 c13a595f3942ed5897ad8c1ad8e05f4b 275 Pfam PF01614 Bacterial transcriptional regulator 138 252 2.2E-12 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal LH59_26065 8217857cb457012bf742e18dab234542 509 ProSitePatterns PS00216 Sugar transport proteins signature 1. 66 82 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 LH59_26065 8217857cb457012bf742e18dab234542 509 Pfam PF07690 Major Facilitator Superfamily 16 406 6.8E-46 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_26065 8217857cb457012bf742e18dab234542 509 Gene3D G3DSA:1.20.1250.20 231 431 9.5E-13 T 14-10-2018 LH59_26065 8217857cb457012bf742e18dab234542 509 SUPERFAMILY SSF103473 11 501 4.45E-57 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_26065 8217857cb457012bf742e18dab234542 509 Gene3D G3DSA:1.20.1720.10 13 230 4.7E-41 T 14-10-2018 LH59_00015 2c0373592dbf9b95a9d18b2c23c00fd8 815 Gene3D G3DSA:3.30.230.10 231 406 7.6E-70 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup LH59_00015 2c0373592dbf9b95a9d18b2c23c00fd8 815 Gene3D G3DSA:3.40.50.670 704 813 6.2E-27 T 14-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 LH59_00015 2c0373592dbf9b95a9d18b2c23c00fd8 815 PRINTS PR01159 DNA gyrase subunit B signature 206 219 1.8E-76 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 LH59_00015 2c0373592dbf9b95a9d18b2c23c00fd8 815 PRINTS PR01159 DNA gyrase subunit B signature 326 342 1.8E-76 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 LH59_00015 2c0373592dbf9b95a9d18b2c23c00fd8 815 PRINTS PR01159 DNA gyrase subunit B signature 768 780 1.8E-76 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 LH59_00015 2c0373592dbf9b95a9d18b2c23c00fd8 815 PRINTS PR01159 DNA gyrase subunit B signature 256 274 1.8E-76 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 LH59_00015 2c0373592dbf9b95a9d18b2c23c00fd8 815 PRINTS PR01159 DNA gyrase subunit B signature 14 24 1.8E-76 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 LH59_00015 2c0373592dbf9b95a9d18b2c23c00fd8 815 PRINTS PR01159 DNA gyrase subunit B signature 230 252 1.8E-76 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 LH59_00015 2c0373592dbf9b95a9d18b2c23c00fd8 815 PRINTS PR01159 DNA gyrase subunit B signature 374 388 1.8E-76 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 LH59_00015 2c0373592dbf9b95a9d18b2c23c00fd8 815 PRINTS PR01159 DNA gyrase subunit B signature 784 800 1.8E-76 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 LH59_00015 2c0373592dbf9b95a9d18b2c23c00fd8 815 PRINTS PR01159 DNA gyrase subunit B signature 191 206 1.8E-76 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 LH59_00015 2c0373592dbf9b95a9d18b2c23c00fd8 815 PRINTS PR01159 DNA gyrase subunit B signature 484 493 1.8E-76 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 LH59_00015 2c0373592dbf9b95a9d18b2c23c00fd8 815 PRINTS PR01159 DNA gyrase subunit B signature 388 408 1.8E-76 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 LH59_00015 2c0373592dbf9b95a9d18b2c23c00fd8 815 SMART SM00433 44 808 6.7E-259 T 14-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 LH59_00015 2c0373592dbf9b95a9d18b2c23c00fd8 815 Pfam PF00204 DNA gyrase B 231 404 2.0E-57 T 14-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 LH59_00015 2c0373592dbf9b95a9d18b2c23c00fd8 815 SUPERFAMILY SSF54211 231 406 6.45E-56 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold LH59_00015 2c0373592dbf9b95a9d18b2c23c00fd8 815 Gene3D G3DSA:3.40.50.670 412 582 1.3E-72 T 14-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 LH59_00015 2c0373592dbf9b95a9d18b2c23c00fd8 815 SUPERFAMILY SSF55874 14 226 2.36E-68 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_00015 2c0373592dbf9b95a9d18b2c23c00fd8 815 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 11 815 99.095 T 14-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 LH59_00015 2c0373592dbf9b95a9d18b2c23c00fd8 815 Pfam PF01751 Toprim domain 433 544 3.0E-17 T 14-10-2018 IPR006171 TOPRIM domain LH59_00015 2c0373592dbf9b95a9d18b2c23c00fd8 815 SUPERFAMILY SSF56719 408 806 3.14E-84 T 14-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 LH59_00015 2c0373592dbf9b95a9d18b2c23c00fd8 815 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 744 804 1.9E-29 T 14-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 LH59_00015 2c0373592dbf9b95a9d18b2c23c00fd8 815 SMART SM00387 40 186 4.3E-27 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_00015 2c0373592dbf9b95a9d18b2c23c00fd8 815 Gene3D G3DSA:3.30.565.10 11 230 2.7E-91 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_00015 2c0373592dbf9b95a9d18b2c23c00fd8 815 PRINTS PR00418 DNA topoisomerase II family signature 434 448 6.1E-68 T 14-10-2018 LH59_00015 2c0373592dbf9b95a9d18b2c23c00fd8 815 PRINTS PR00418 DNA topoisomerase II family signature 538 550 6.1E-68 T 14-10-2018 LH59_00015 2c0373592dbf9b95a9d18b2c23c00fd8 815 PRINTS PR00418 DNA topoisomerase II family signature 282 295 6.1E-68 T 14-10-2018 LH59_00015 2c0373592dbf9b95a9d18b2c23c00fd8 815 PRINTS PR00418 DNA topoisomerase II family signature 44 59 6.1E-68 T 14-10-2018 LH59_00015 2c0373592dbf9b95a9d18b2c23c00fd8 815 PRINTS PR00418 DNA topoisomerase II family signature 518 535 6.1E-68 T 14-10-2018 LH59_00015 2c0373592dbf9b95a9d18b2c23c00fd8 815 PRINTS PR00418 DNA topoisomerase II family signature 124 138 6.1E-68 T 14-10-2018 LH59_00015 2c0373592dbf9b95a9d18b2c23c00fd8 815 PRINTS PR00418 DNA topoisomerase II family signature 500 516 6.1E-68 T 14-10-2018 LH59_00015 2c0373592dbf9b95a9d18b2c23c00fd8 815 PRINTS PR00418 DNA topoisomerase II family signature 747 763 6.1E-68 T 14-10-2018 LH59_00015 2c0373592dbf9b95a9d18b2c23c00fd8 815 PRINTS PR00418 DNA topoisomerase II family signature 79 92 6.1E-68 T 14-10-2018 LH59_00015 2c0373592dbf9b95a9d18b2c23c00fd8 815 ProSitePatterns PS00177 DNA topoisomerase II signature. 436 444 - T 14-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 LH59_00015 2c0373592dbf9b95a9d18b2c23c00fd8 815 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 14 815 3.6E-294 T 14-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 LH59_00015 2c0373592dbf9b95a9d18b2c23c00fd8 815 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 41 182 1.8E-22 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_15550 5b798f72f320d339e33c4d0523baf0c5 264 SUPERFAMILY SSF103088 153 261 1.31E-34 T 14-10-2018 IPR036737 OmpA-like domain superfamily LH59_15550 5b798f72f320d339e33c4d0523baf0c5 264 Gene3D G3DSA:3.30.1330.60 136 264 6.1E-39 T 14-10-2018 IPR036737 OmpA-like domain superfamily LH59_15550 5b798f72f320d339e33c4d0523baf0c5 264 Gene3D G3DSA:3.40.1520.20 28 135 8.6E-9 T 14-10-2018 LH59_15550 5b798f72f320d339e33c4d0523baf0c5 264 PRINTS PR01021 OMPA domain signature 192 207 9.4E-13 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 LH59_15550 5b798f72f320d339e33c4d0523baf0c5 264 PRINTS PR01021 OMPA domain signature 162 184 9.4E-13 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 LH59_15550 5b798f72f320d339e33c4d0523baf0c5 264 PRINTS PR01021 OMPA domain signature 207 223 9.4E-13 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 LH59_15550 5b798f72f320d339e33c4d0523baf0c5 264 Pfam PF00691 OmpA family 162 256 7.3E-25 T 14-10-2018 IPR006665 OmpA-like domain LH59_15550 5b798f72f320d339e33c4d0523baf0c5 264 Pfam PF04972 BON domain 28 71 9.0E-4 T 14-10-2018 IPR007055 BON domain LH59_15550 5b798f72f320d339e33c4d0523baf0c5 264 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 245 264 2.0E-6 T 14-10-2018 LH59_15550 5b798f72f320d339e33c4d0523baf0c5 264 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 225 244 2.0E-6 T 14-10-2018 LH59_15550 5b798f72f320d339e33c4d0523baf0c5 264 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 207 224 2.0E-6 T 14-10-2018 LH59_17710 6bb1b841875c6b330ab7d71e1d275d84 398 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 4 392 3.6E-125 T 14-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 LH59_17710 6bb1b841875c6b330ab7d71e1d275d84 398 Pfam PF02441 Flavoprotein 7 178 5.1E-43 T 14-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 LH59_17710 6bb1b841875c6b330ab7d71e1d275d84 398 Gene3D G3DSA:3.40.50.10300 185 397 3.8E-69 T 14-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 LH59_17710 6bb1b841875c6b330ab7d71e1d275d84 398 SUPERFAMILY SSF52507 3 182 1.96E-59 T 14-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 LH59_17710 6bb1b841875c6b330ab7d71e1d275d84 398 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 186 367 4.5E-62 T 14-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 LH59_17710 6bb1b841875c6b330ab7d71e1d275d84 398 Gene3D G3DSA:3.40.50.1950 2 184 2.9E-56 T 14-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 LH59_17710 6bb1b841875c6b330ab7d71e1d275d84 398 SUPERFAMILY SSF102645 184 396 4.97E-68 T 14-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 LH59_27470 b25962d5106cc0564913fbc2c56f4290 184 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 179 1.0E-63 T 14-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 LH59_27470 b25962d5106cc0564913fbc2c56f4290 184 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 3 178 2.3E-75 T 14-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 LH59_27470 b25962d5106cc0564913fbc2c56f4290 184 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 176 5.2E-69 T 14-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 LH59_27470 b25962d5106cc0564913fbc2c56f4290 184 SUPERFAMILY SSF51182 1 180 2.87E-71 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_27470 b25962d5106cc0564913fbc2c56f4290 184 Gene3D G3DSA:2.60.120.10 1 182 3.0E-68 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_04820 9c4c4e43229961f2db24c17acbafafab 597 Pfam PF02653 Branched-chain amino acid transport system / permease component 26 306 3.0E-30 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_04820 9c4c4e43229961f2db24c17acbafafab 597 SUPERFAMILY SSF52540 348 593 9.87E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_04820 9c4c4e43229961f2db24c17acbafafab 597 Pfam PF00005 ABC transporter 367 523 2.1E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_04820 9c4c4e43229961f2db24c17acbafafab 597 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 572 594 7.1E-11 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal LH59_04820 9c4c4e43229961f2db24c17acbafafab 597 SMART SM00382 374 572 5.8E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_04820 9c4c4e43229961f2db24c17acbafafab 597 Gene3D G3DSA:3.40.50.300 346 595 4.0E-56 T 14-10-2018 LH59_16670 8b7a33439eb3915ca60b8b5797c91d51 295 Gene3D G3DSA:1.10.10.10 1 88 1.1E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_16670 8b7a33439eb3915ca60b8b5797c91d51 295 Pfam PF03466 LysR substrate binding domain 88 294 2.1E-28 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_16670 8b7a33439eb3915ca60b8b5797c91d51 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 3.0E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_16670 8b7a33439eb3915ca60b8b5797c91d51 295 Gene3D G3DSA:3.40.190.290 90 294 7.2E-25 T 14-10-2018 LH59_16670 8b7a33439eb3915ca60b8b5797c91d51 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.1E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_16670 8b7a33439eb3915ca60b8b5797c91d51 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.1E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_16670 8b7a33439eb3915ca60b8b5797c91d51 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.1E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_16670 8b7a33439eb3915ca60b8b5797c91d51 295 SUPERFAMILY SSF53850 89 295 1.5E-28 T 14-10-2018 LH59_16670 8b7a33439eb3915ca60b8b5797c91d51 295 SUPERFAMILY SSF46785 1 82 7.62E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_03800 461e6413e78753a73c6eaecec8fb99d3 440 Gene3D G3DSA:2.120.10.30 176 440 2.9E-86 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like LH59_03800 461e6413e78753a73c6eaecec8fb99d3 440 TIGRFAM TIGR02800 propeller_TolB: Tol-Pal system beta propeller repeat protein TolB 31 436 1.9E-156 T 14-10-2018 IPR014167 Tol-Pal system protein TolB GO:0017038|GO:0042597 LH59_03800 461e6413e78753a73c6eaecec8fb99d3 440 Gene3D G3DSA:3.40.50.10070 36 175 1.6E-33 T 14-10-2018 IPR036752 TolB, N-terminal domain superfamily GO:0015031|GO:0042597 LH59_03800 461e6413e78753a73c6eaecec8fb99d3 440 Hamap MF_00671 Tol-Pal system protein TolB [tolB]. 21 435 45.251 T 14-10-2018 IPR014167 Tol-Pal system protein TolB GO:0017038|GO:0042597 LH59_03800 461e6413e78753a73c6eaecec8fb99d3 440 SUPERFAMILY SSF52964 47 172 7.19E-31 T 14-10-2018 LH59_03800 461e6413e78753a73c6eaecec8fb99d3 440 Pfam PF04052 TolB amino-terminal domain 40 139 1.8E-22 T 14-10-2018 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 LH59_03800 461e6413e78753a73c6eaecec8fb99d3 440 SUPERFAMILY SSF69304 165 437 4.84E-54 T 14-10-2018 LH59_03800 461e6413e78753a73c6eaecec8fb99d3 440 Pfam PF07676 WD40-like Beta Propeller Repeat 208 236 3.4E-8 T 14-10-2018 IPR011659 WD40-like Beta Propeller LH59_03800 461e6413e78753a73c6eaecec8fb99d3 440 Pfam PF07676 WD40-like Beta Propeller Repeat 289 325 4.8E-15 T 14-10-2018 IPR011659 WD40-like Beta Propeller LH59_03800 461e6413e78753a73c6eaecec8fb99d3 440 Pfam PF07676 WD40-like Beta Propeller Repeat 334 367 2.2E-8 T 14-10-2018 IPR011659 WD40-like Beta Propeller LH59_03800 461e6413e78753a73c6eaecec8fb99d3 440 Pfam PF07676 WD40-like Beta Propeller Repeat 246 280 8.3E-7 T 14-10-2018 IPR011659 WD40-like Beta Propeller LH59_23415 3f2ba2671a1a8a3143eda9b9919b9a3c 296 SUPERFAMILY SSF46785 1 113 1.41E-25 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_23415 3f2ba2671a1a8a3143eda9b9919b9a3c 296 Gene3D G3DSA:3.40.190.290 92 294 3.5E-42 T 14-10-2018 LH59_23415 3f2ba2671a1a8a3143eda9b9919b9a3c 296 Pfam PF03466 LysR substrate binding domain 89 290 1.2E-36 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_23415 3f2ba2671a1a8a3143eda9b9919b9a3c 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 1.3E-16 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_23415 3f2ba2671a1a8a3143eda9b9919b9a3c 296 Gene3D G3DSA:1.10.10.10 3 90 1.9E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_23415 3f2ba2671a1a8a3143eda9b9919b9a3c 296 SUPERFAMILY SSF53850 89 291 1.78E-38 T 14-10-2018 LH59_24745 0f786d259e8d965b2ded910659653949 687 SUPERFAMILY SSF141868 440 684 2.75E-90 T 14-10-2018 IPR035919 EAL domain superfamily LH59_24745 0f786d259e8d965b2ded910659653949 687 Pfam PF00563 EAL domain 441 675 3.5E-74 T 14-10-2018 IPR001633 EAL domain LH59_24745 0f786d259e8d965b2ded910659653949 687 Gene3D G3DSA:3.30.70.270 259 436 2.0E-61 T 14-10-2018 LH59_24745 0f786d259e8d965b2ded910659653949 687 Pfam PF00990 Diguanylate cyclase, GGDEF domain 264 417 4.2E-49 T 14-10-2018 IPR000160 GGDEF domain LH59_24745 0f786d259e8d965b2ded910659653949 687 Pfam PF03707 Bacterial signalling protein N terminal repeat 183 246 1.9E-11 T 14-10-2018 IPR005330 MHYT domain LH59_24745 0f786d259e8d965b2ded910659653949 687 Pfam PF03707 Bacterial signalling protein N terminal repeat 53 110 2.2E-21 T 14-10-2018 IPR005330 MHYT domain LH59_24745 0f786d259e8d965b2ded910659653949 687 Pfam PF03707 Bacterial signalling protein N terminal repeat 116 171 5.6E-16 T 14-10-2018 IPR005330 MHYT domain LH59_24745 0f786d259e8d965b2ded910659653949 687 SMART SM00267 253 424 6.0E-65 T 14-10-2018 IPR000160 GGDEF domain LH59_24745 0f786d259e8d965b2ded910659653949 687 SMART SM00052 434 680 3.1E-121 T 14-10-2018 IPR001633 EAL domain LH59_24745 0f786d259e8d965b2ded910659653949 687 SUPERFAMILY SSF55073 269 426 9.73E-52 T 14-10-2018 IPR029787 Nucleotide cyclase LH59_24745 0f786d259e8d965b2ded910659653949 687 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 262 418 5.9E-43 T 14-10-2018 IPR000160 GGDEF domain LH59_24745 0f786d259e8d965b2ded910659653949 687 Gene3D G3DSA:3.20.20.450 437 686 5.2E-102 T 14-10-2018 IPR035919 EAL domain superfamily LH59_22015 25b220c3bf41af41274ff3aa0af57f6c 730 SMART SM00388 507 569 1.2E-12 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_22015 25b220c3bf41af41274ff3aa0af57f6c 730 Gene3D G3DSA:3.30.565.10 573 722 1.4E-28 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_22015 25b220c3bf41af41274ff3aa0af57f6c 730 Gene3D G3DSA:3.30.450.270 312 490 6.8E-149 T 14-10-2018 LH59_22015 25b220c3bf41af41274ff3aa0af57f6c 730 SUPERFAMILY SSF55785 10 121 5.02E-25 T 14-10-2018 IPR035965 PAS domain superfamily LH59_22015 25b220c3bf41af41274ff3aa0af57f6c 730 Pfam PF08446 PAS fold 16 116 1.0E-8 T 14-10-2018 IPR013654 PAS fold-2 GO:0006355 LH59_22015 25b220c3bf41af41274ff3aa0af57f6c 730 SUPERFAMILY SSF55781 130 309 1.79E-54 T 14-10-2018 LH59_22015 25b220c3bf41af41274ff3aa0af57f6c 730 Pfam PF00512 His Kinase A (phospho-acceptor) domain 508 569 1.1E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_22015 25b220c3bf41af41274ff3aa0af57f6c 730 PRINTS PR01033 Phytochrome signature 244 265 2.5E-17 T 14-10-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 LH59_22015 25b220c3bf41af41274ff3aa0af57f6c 730 PRINTS PR01033 Phytochrome signature 157 176 2.5E-17 T 14-10-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 LH59_22015 25b220c3bf41af41274ff3aa0af57f6c 730 PRINTS PR01033 Phytochrome signature 426 445 2.5E-17 T 14-10-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 LH59_22015 25b220c3bf41af41274ff3aa0af57f6c 730 PRINTS PR01033 Phytochrome signature 460 478 2.5E-17 T 14-10-2018 IPR001294 Phytochrome GO:0006355|GO:0009584 LH59_22015 25b220c3bf41af41274ff3aa0af57f6c 730 SMART SM00065 142 316 9.9E-9 T 14-10-2018 IPR003018 GAF domain GO:0005515 LH59_22015 25b220c3bf41af41274ff3aa0af57f6c 730 SUPERFAMILY SSF55874 559 722 3.14E-29 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_22015 25b220c3bf41af41274ff3aa0af57f6c 730 SUPERFAMILY SSF55781 294 494 3.53E-36 T 14-10-2018 LH59_22015 25b220c3bf41af41274ff3aa0af57f6c 730 SUPERFAMILY SSF47384 499 568 2.35E-11 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 LH59_22015 25b220c3bf41af41274ff3aa0af57f6c 730 SMART SM00387 613 724 2.4E-22 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_22015 25b220c3bf41af41274ff3aa0af57f6c 730 Pfam PF01590 GAF domain 143 307 2.7E-17 T 14-10-2018 IPR003018 GAF domain GO:0005515 LH59_22015 25b220c3bf41af41274ff3aa0af57f6c 730 Gene3D G3DSA:3.30.450.20 23 245 6.8E-149 T 14-10-2018 LH59_22015 25b220c3bf41af41274ff3aa0af57f6c 730 Gene3D G3DSA:1.10.287.130 498 570 8.1E-13 T 14-10-2018 LH59_22015 25b220c3bf41af41274ff3aa0af57f6c 730 Pfam PF00360 Phytochrome region 325 496 1.4E-35 T 14-10-2018 IPR013515 Phytochrome, central region GO:0006355|GO:0009584|GO:0018298 LH59_22015 25b220c3bf41af41274ff3aa0af57f6c 730 Gene3D G3DSA:3.30.450.40 13 473 6.8E-149 T 14-10-2018 IPR029016 GAF-like domain superfamily LH59_22015 25b220c3bf41af41274ff3aa0af57f6c 730 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 614 721 1.2E-13 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_11650 e8511ec931514063577cfe23360636fb 292 SUPERFAMILY SSF46934 3 56 7.96E-14 T 14-10-2018 IPR009060 UBA-like superfamily GO:0005515 LH59_11650 e8511ec931514063577cfe23360636fb 292 SUPERFAMILY SSF54713 151 288 1.31E-46 T 14-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 LH59_11650 e8511ec931514063577cfe23360636fb 292 Gene3D G3DSA:3.30.479.20 57 148 5.9E-28 T 14-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 LH59_11650 e8511ec931514063577cfe23360636fb 292 Gene3D G3DSA:3.30.479.20 155 270 1.5E-38 T 14-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 LH59_11650 e8511ec931514063577cfe23360636fb 292 Pfam PF00889 Elongation factor TS 73 271 5.6E-70 T 14-10-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0006414 Reactome: R-HSA-5389840 LH59_11650 e8511ec931514063577cfe23360636fb 292 Gene3D G3DSA:1.10.8.10 1 56 2.4E-21 T 14-10-2018 LH59_11650 e8511ec931514063577cfe23360636fb 292 Hamap MF_00050 Elongation factor Ts [tsf]. 1 288 78.678 T 14-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 LH59_11650 e8511ec931514063577cfe23360636fb 292 Gene3D G3DSA:1.10.286.20 190 236 1.5E-38 T 14-10-2018 LH59_11650 e8511ec931514063577cfe23360636fb 292 ProSitePatterns PS01127 Elongation factor Ts signature 2. 77 87 - T 14-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 LH59_11650 e8511ec931514063577cfe23360636fb 292 SUPERFAMILY SSF54713 56 147 7.03E-23 T 14-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 LH59_11650 e8511ec931514063577cfe23360636fb 292 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 287 4.7E-92 T 14-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 LH59_07755 54f38319edad9e5797bcc340dda22a9e 340 PIRSF PIRSF002825 1 332 5.0E-95 T 14-10-2018 IPR026045 Ferric binding protein LH59_07755 54f38319edad9e5797bcc340dda22a9e 340 Pfam PF13343 Bacterial extracellular solute-binding protein 73 313 9.1E-33 T 14-10-2018 LH59_07755 54f38319edad9e5797bcc340dda22a9e 340 SUPERFAMILY SSF53850 25 329 6.42E-74 T 14-10-2018 LH59_07755 54f38319edad9e5797bcc340dda22a9e 340 TIGRFAM TIGR03261 phnS2: putative 2-aminoethylphosphonate ABC transporter, periplasmic 2-aminoethylphosphonate-binding protein 8 336 1.3E-159 T 14-10-2018 IPR017663 ABC transport system, 1-aminoethylphosphonate-binding protein, putative LH59_07755 54f38319edad9e5797bcc340dda22a9e 340 Gene3D G3DSA:3.40.190.10 28 301 3.5E-89 T 14-10-2018 LH59_07755 54f38319edad9e5797bcc340dda22a9e 340 Gene3D G3DSA:3.40.190.10 129 315 3.5E-89 T 14-10-2018 LH59_19245 604ba08971658bab02ec7eb0292a8457 762 PIRSF PIRSF036389 1 762 2.2E-239 T 14-10-2018 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related LH59_19245 604ba08971658bab02ec7eb0292a8457 762 SUPERFAMILY SSF56003 52 250 1.36E-41 T 14-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 LH59_19245 604ba08971658bab02ec7eb0292a8457 762 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 218 265 1.4E-4 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead LH59_19245 604ba08971658bab02ec7eb0292a8457 762 Gene3D G3DSA:3.30.365.10 619 761 9.9E-40 T 14-10-2018 LH59_19245 604ba08971658bab02ec7eb0292a8457 762 SUPERFAMILY SSF56003 328 759 9.65E-107 T 14-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 LH59_19245 604ba08971658bab02ec7eb0292a8457 762 Gene3D G3DSA:3.30.365.10 50 187 5.2E-22 T 14-10-2018 LH59_19245 604ba08971658bab02ec7eb0292a8457 762 SMART SM01008 217 306 8.8E-26 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead LH59_19245 604ba08971658bab02ec7eb0292a8457 762 Gene3D G3DSA:3.30.365.10 360 453 9.5E-47 T 14-10-2018 LH59_19245 604ba08971658bab02ec7eb0292a8457 762 Gene3D G3DSA:3.30.365.10 334 558 9.5E-47 T 14-10-2018 LH59_19245 604ba08971658bab02ec7eb0292a8457 762 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 326 566 3.4E-33 T 14-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 LH59_19245 604ba08971658bab02ec7eb0292a8457 762 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 627 707 3.3E-16 T 14-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 LH59_19245 604ba08971658bab02ec7eb0292a8457 762 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 56 199 1.3E-13 T 14-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 LH59_19245 604ba08971658bab02ec7eb0292a8457 762 Gene3D G3DSA:3.90.1170.50 188 301 3.4E-11 T 14-10-2018 LH59_07880 e0e0e25943c0a14ca336c525e7eb6838 479 Gene3D G3DSA:3.90.1150.10 108 473 8.2E-97 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_07880 e0e0e25943c0a14ca336c525e7eb6838 479 SUPERFAMILY SSF46785 2 73 6.82E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_07880 e0e0e25943c0a14ca336c525e7eb6838 479 SMART SM00345 10 69 3.1E-11 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_07880 e0e0e25943c0a14ca336c525e7eb6838 479 SUPERFAMILY SSF53383 119 474 4.3E-90 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_07880 e0e0e25943c0a14ca336c525e7eb6838 479 Pfam PF00155 Aminotransferase class I and II 128 463 2.4E-28 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LH59_07880 e0e0e25943c0a14ca336c525e7eb6838 479 Gene3D G3DSA:3.40.640.10 149 368 8.2E-97 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_07880 e0e0e25943c0a14ca336c525e7eb6838 479 Gene3D G3DSA:1.10.10.10 2 71 7.2E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_07880 e0e0e25943c0a14ca336c525e7eb6838 479 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 69 4.7E-11 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_27345 f256ddec6c1443cadd6508bcecfdece0 375 Gene3D G3DSA:3.40.50.2000 184 354 2.4E-21 T 14-10-2018 LH59_27345 f256ddec6c1443cadd6508bcecfdece0 375 Pfam PF13692 Glycosyl transferases group 1 197 335 1.6E-12 T 14-10-2018 LH59_27345 f256ddec6c1443cadd6508bcecfdece0 375 Gene3D G3DSA:3.40.50.2000 4 179 7.5E-12 T 14-10-2018 LH59_27345 f256ddec6c1443cadd6508bcecfdece0 375 Pfam PF13439 Glycosyltransferase Family 4 22 165 2.0E-13 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 LH59_27345 f256ddec6c1443cadd6508bcecfdece0 375 SUPERFAMILY SSF53756 4 371 3.66E-39 T 14-10-2018 LH59_11765 092414ffdbded0e3fec1d86a80e407da 155 Pfam PF01668 SmpB protein 3 146 2.0E-57 T 14-10-2018 IPR000037 SsrA-binding protein GO:0003723 LH59_11765 092414ffdbded0e3fec1d86a80e407da 155 Hamap MF_00023 SsrA-binding protein [smpB]. 1 150 70.967 T 14-10-2018 IPR000037 SsrA-binding protein GO:0003723 LH59_11765 092414ffdbded0e3fec1d86a80e407da 155 Gene3D G3DSA:2.40.280.10 1 124 1.5E-46 T 14-10-2018 IPR023620 Small protein B LH59_11765 092414ffdbded0e3fec1d86a80e407da 155 TIGRFAM TIGR00086 smpB: SsrA-binding protein 3 145 7.0E-52 T 14-10-2018 IPR000037 SsrA-binding protein GO:0003723 LH59_11765 092414ffdbded0e3fec1d86a80e407da 155 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 3 127 3.0E-64 T 14-10-2018 IPR000037 SsrA-binding protein GO:0003723 LH59_11765 092414ffdbded0e3fec1d86a80e407da 155 ProSitePatterns PS01317 SsrA-binding protein. 21 33 - T 14-10-2018 IPR020081 SsrA-binding protein, conserved site LH59_11765 092414ffdbded0e3fec1d86a80e407da 155 SUPERFAMILY SSF74982 3 127 3.79E-48 T 14-10-2018 IPR023620 Small protein B LH59_25720 08b45a3c2d6b2d900f1e30108e800cf8 268 SUPERFAMILY SSF48179 161 266 1.19E-25 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 LH59_25720 08b45a3c2d6b2d900f1e30108e800cf8 268 Gene3D G3DSA:3.40.50.720 1 162 1.3E-43 T 14-10-2018 LH59_25720 08b45a3c2d6b2d900f1e30108e800cf8 268 SUPERFAMILY SSF51735 4 159 2.51E-30 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_25720 08b45a3c2d6b2d900f1e30108e800cf8 268 PIRSF PIRSF000193 2 268 4.0E-61 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 LH59_25720 08b45a3c2d6b2d900f1e30108e800cf8 268 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 5 265 4.3E-67 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 LH59_25720 08b45a3c2d6b2d900f1e30108e800cf8 268 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 3 265 23.06 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 LH59_25720 08b45a3c2d6b2d900f1e30108e800cf8 268 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 97 1.1E-12 T 14-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal LH59_25720 08b45a3c2d6b2d900f1e30108e800cf8 268 Gene3D G3DSA:1.10.3730.10 163 267 3.6E-29 T 14-10-2018 LH59_25720 08b45a3c2d6b2d900f1e30108e800cf8 268 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 161 265 8.3E-25 T 14-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 LH59_27640 3726542fca5a62aa009e8665f7c49aab 220 Gene3D G3DSA:3.40.30.10 4 200 1.1E-61 T 14-10-2018 LH59_27640 3726542fca5a62aa009e8665f7c49aab 220 SUPERFAMILY SSF52833 4 86 1.36E-18 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_27640 3726542fca5a62aa009e8665f7c49aab 220 SUPERFAMILY SSF47616 80 202 3.69E-18 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily LH59_27640 3726542fca5a62aa009e8665f7c49aab 220 Gene3D G3DSA:1.20.1050.10 83 193 1.1E-61 T 14-10-2018 LH59_27640 3726542fca5a62aa009e8665f7c49aab 220 Pfam PF13417 Glutathione S-transferase, N-terminal domain 10 80 1.8E-11 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 LH59_15660 04b20a4e471a185801eb067e8eee174b 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 54 323 4.9E-79 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_15660 04b20a4e471a185801eb067e8eee174b 328 Gene3D G3DSA:3.40.190.150 34 312 2.7E-91 T 14-10-2018 LH59_15660 04b20a4e471a185801eb067e8eee174b 328 SUPERFAMILY SSF53850 119 283 1.19E-9 T 14-10-2018 LH59_15660 04b20a4e471a185801eb067e8eee174b 328 Gene3D G3DSA:3.40.190.10 131 252 2.7E-91 T 14-10-2018 LH59_15660 04b20a4e471a185801eb067e8eee174b 328 PIRSF PIRSF017082 1 327 2.0E-87 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_25105 28f716c320761f76f3255f48d8d8c07f 298 SUPERFAMILY SSF46785 2 113 5.9E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_25105 28f716c320761f76f3255f48d8d8c07f 298 Gene3D G3DSA:1.10.10.10 1 84 4.4E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_25105 28f716c320761f76f3255f48d8d8c07f 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 7.0E-16 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_25105 28f716c320761f76f3255f48d8d8c07f 298 Gene3D G3DSA:3.40.190.290 92 294 3.5E-44 T 14-10-2018 LH59_25105 28f716c320761f76f3255f48d8d8c07f 298 Pfam PF03466 LysR substrate binding domain 90 291 1.0E-46 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_25105 28f716c320761f76f3255f48d8d8c07f 298 SUPERFAMILY SSF53850 91 293 1.47E-43 T 14-10-2018 LH59_02050 78153370085af7893452df44c3a6e5f8 687 Gene3D G3DSA:1.10.10.160 113 188 3.0E-87 T 14-10-2018 IPR013986 DExx box DNA helicase domain superfamily LH59_02050 78153370085af7893452df44c3a6e5f8 687 Pfam PF00580 UvrD/REP helicase N-terminal domain 11 270 1.3E-65 T 14-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 LH59_02050 78153370085af7893452df44c3a6e5f8 687 Gene3D G3DSA:3.40.50.300 11 272 3.0E-87 T 14-10-2018 LH59_02050 78153370085af7893452df44c3a6e5f8 687 SUPERFAMILY SSF52540 5 656 1.39E-149 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_02050 78153370085af7893452df44c3a6e5f8 687 Gene3D G3DSA:3.40.50.300 279 655 6.6E-104 T 14-10-2018 LH59_02050 78153370085af7893452df44c3a6e5f8 687 Hamap MF_01920 ATP-dependent DNA helicase Rep [rep]. 9 686 37.405 T 14-10-2018 IPR005752 ATP-dependent DNA helicase Rep GO:0003677|GO:0004003|GO:0005524|GO:0006268 LH59_02050 78153370085af7893452df44c3a6e5f8 687 Pfam PF13361 UvrD-like helicase C-terminal domain 276 636 2.0E-60 T 14-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 LH59_02050 78153370085af7893452df44c3a6e5f8 687 Gene3D G3DSA:1.10.486.10 382 555 6.6E-104 T 14-10-2018 LH59_19895 8c2cb42ede1600870e41489ea5078b5e 303 Pfam PF01904 Protein of unknown function DUF72 22 293 2.8E-55 T 14-10-2018 IPR002763 Protein of unknown function DUF72 LH59_19895 8c2cb42ede1600870e41489ea5078b5e 303 SUPERFAMILY SSF117396 1 296 1.01E-67 T 14-10-2018 IPR036520 UPF0759 superfamily LH59_19895 8c2cb42ede1600870e41489ea5078b5e 303 Gene3D G3DSA:3.20.20.410 2 302 1.9E-70 T 14-10-2018 IPR036520 UPF0759 superfamily LH59_10580 1de905e4ed92ea4368ae570c2c571d02 294 Gene3D G3DSA:3.90.226.10 3 226 4.3E-81 T 14-10-2018 LH59_10580 1de905e4ed92ea4368ae570c2c571d02 294 SUPERFAMILY SSF52096 25 265 9.95E-32 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily LH59_10580 1de905e4ed92ea4368ae570c2c571d02 294 Pfam PF00378 Enoyl-CoA hydratase/isomerase 111 207 8.7E-14 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 LH59_04755 25d0d9ed06955e12f5ba4ada34d076e4 414 SUPERFAMILY SSF50022 8 163 3.14E-45 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 LH59_04755 25d0d9ed06955e12f5ba4ada34d076e4 414 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 147 173 5.6E-30 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 LH59_04755 25d0d9ed06955e12f5ba4ada34d076e4 414 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 74 94 5.6E-30 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 LH59_04755 25d0d9ed06955e12f5ba4ada34d076e4 414 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 186 208 5.6E-30 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 LH59_04755 25d0d9ed06955e12f5ba4ada34d076e4 414 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 22 47 5.6E-30 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 LH59_04755 25d0d9ed06955e12f5ba4ada34d076e4 414 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 95 115 5.6E-30 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 LH59_04755 25d0d9ed06955e12f5ba4ada34d076e4 414 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 53 68 5.6E-30 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 LH59_04755 25d0d9ed06955e12f5ba4ada34d076e4 414 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 81 104 - T 14-10-2018 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0051537|GO:0055114 LH59_04755 25d0d9ed06955e12f5ba4ada34d076e4 414 Gene3D G3DSA:2.102.10.10 38 171 3.4E-94 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 LH59_04755 25d0d9ed06955e12f5ba4ada34d076e4 414 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 195 411 9.2E-18 T 14-10-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0044237|GO:0051537|GO:0055114 LH59_04755 25d0d9ed06955e12f5ba4ada34d076e4 414 Gene3D G3DSA:3.90.380.10 15 410 3.4E-94 T 14-10-2018 LH59_04755 25d0d9ed06955e12f5ba4ada34d076e4 414 Pfam PF00355 Rieske [2Fe-2S] domain 38 124 2.6E-20 T 14-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 LH59_04755 25d0d9ed06955e12f5ba4ada34d076e4 414 SUPERFAMILY SSF55961 172 410 3.77E-51 T 14-10-2018 LH59_05970 5104c50a97c924e64ea3366d8fa1f1ed 206 SMART SM00895 79 203 2.3E-13 T 14-10-2018 IPR011711 GntR, C-terminal LH59_05970 5104c50a97c924e64ea3366d8fa1f1ed 206 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 69 1.0E-8 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_05970 5104c50a97c924e64ea3366d8fa1f1ed 206 Gene3D G3DSA:1.20.120.530 75 205 6.1E-19 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_05970 5104c50a97c924e64ea3366d8fa1f1ed 206 SMART SM00345 11 69 3.9E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_05970 5104c50a97c924e64ea3366d8fa1f1ed 206 SUPERFAMILY SSF46785 11 73 1.36E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_05970 5104c50a97c924e64ea3366d8fa1f1ed 206 SUPERFAMILY SSF48008 75 201 6.02E-19 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_05970 5104c50a97c924e64ea3366d8fa1f1ed 206 Pfam PF07729 FCD domain 79 201 7.0E-20 T 14-10-2018 IPR011711 GntR, C-terminal LH59_05970 5104c50a97c924e64ea3366d8fa1f1ed 206 Gene3D G3DSA:1.10.10.10 1 70 1.6E-11 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_27780 2d12890f370bebde11ad98a832eeb771 131 Gene3D G3DSA:3.30.1490.10 74 131 1.5E-24 T 14-10-2018 LH59_27780 2d12890f370bebde11ad98a832eeb771 131 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 131 32.45 T 14-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27780 2d12890f370bebde11ad98a832eeb771 131 SUPERFAMILY SSF56047 2 130 9.55E-48 T 14-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27780 2d12890f370bebde11ad98a832eeb771 131 Gene3D G3DSA:3.30.1370.30 2 73 1.8E-27 T 14-10-2018 LH59_27780 2d12890f370bebde11ad98a832eeb771 131 Pfam PF00410 Ribosomal protein S8 5 130 8.4E-50 T 14-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27780 2d12890f370bebde11ad98a832eeb771 131 ProSitePatterns PS00053 Ribosomal protein S8 signature. 101 118 - T 14-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_05500 e2884d1fe6c3295974d1d615d618ea68 335 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_05500 e2884d1fe6c3295974d1d615d618ea68 335 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 243 330 2.4E-24 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_05500 e2884d1fe6c3295974d1d615d618ea68 335 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 245 311 1.3E-16 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_05500 e2884d1fe6c3295974d1d615d618ea68 335 SMART SM00382 38 243 3.7E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_05500 e2884d1fe6c3295974d1d615d618ea68 335 Pfam PF00005 ABC transporter 30 193 4.0E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_05500 e2884d1fe6c3295974d1d615d618ea68 335 SUPERFAMILY SSF52540 9 264 4.78E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_05500 e2884d1fe6c3295974d1d615d618ea68 335 Gene3D G3DSA:3.40.50.300 7 334 2.5E-98 T 14-10-2018 LH59_15370 48d321292526e97d4e174a648633cfd9 214 Gene3D G3DSA:2.130.10.10 10 211 4.4E-15 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 LH59_15370 48d321292526e97d4e174a648633cfd9 214 SUPERFAMILY SSF50969 18 201 3.3E-23 T 14-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like LH59_18865 70bca6305fab6b10466a7ada55d9383d 461 SUPERFAMILY SSF53850 104 334 6.18E-41 T 14-10-2018 LH59_18865 70bca6305fab6b10466a7ada55d9383d 461 Gene3D G3DSA:3.40.190.10 195 449 1.1E-115 T 14-10-2018 LH59_18865 70bca6305fab6b10466a7ada55d9383d 461 Pfam PF13379 NMT1-like family 103 341 1.4E-78 T 14-10-2018 LH59_18865 70bca6305fab6b10466a7ada55d9383d 461 Gene3D G3DSA:3.40.190.10 108 444 1.1E-115 T 14-10-2018 LH59_25735 9188906f9439593cf33ec2195f884c68 360 Gene3D G3DSA:3.40.190.10 144 267 1.1E-106 T 14-10-2018 LH59_25735 9188906f9439593cf33ec2195f884c68 360 SUPERFAMILY SSF53850 53 358 4.8E-52 T 14-10-2018 LH59_25735 9188906f9439593cf33ec2195f884c68 360 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 9 26 0.0012 T 14-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal LH59_25735 9188906f9439593cf33ec2195f884c68 360 Pfam PF13416 Bacterial extracellular solute-binding protein 59 306 2.6E-39 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein LH59_25735 9188906f9439593cf33ec2195f884c68 360 Gene3D G3DSA:3.40.190.10 41 357 1.1E-106 T 14-10-2018 LH59_10175 cce582c4b399488b25b5ca4fd9aa71b1 108 PRINTS PR00607 Class IE cytochrome C signature 79 91 3.2E-12 T 14-10-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 LH59_10175 cce582c4b399488b25b5ca4fd9aa71b1 108 PRINTS PR00607 Class IE cytochrome C signature 51 61 3.2E-12 T 14-10-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 LH59_10175 cce582c4b399488b25b5ca4fd9aa71b1 108 PRINTS PR00607 Class IE cytochrome C signature 93 104 3.2E-12 T 14-10-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 LH59_10175 cce582c4b399488b25b5ca4fd9aa71b1 108 PRINTS PR00607 Class IE cytochrome C signature 40 51 3.2E-12 T 14-10-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 LH59_10175 cce582c4b399488b25b5ca4fd9aa71b1 108 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 32 103 2.9E-16 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_10175 cce582c4b399488b25b5ca4fd9aa71b1 108 Gene3D G3DSA:1.10.760.10 22 108 2.0E-34 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_10175 cce582c4b399488b25b5ca4fd9aa71b1 108 SUPERFAMILY SSF46626 4 107 3.25E-16 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_23795 678a2aaa42a29d4fd59f506d2db32e02 231 Pfam PF13599 Pentapeptide repeats (9 copies) 133 200 5.4E-8 T 14-10-2018 IPR001646 Pentapeptide repeat LH59_23795 678a2aaa42a29d4fd59f506d2db32e02 231 Pfam PF13599 Pentapeptide repeats (9 copies) 33 85 6.9E-8 T 14-10-2018 IPR001646 Pentapeptide repeat LH59_23795 678a2aaa42a29d4fd59f506d2db32e02 231 SUPERFAMILY SSF141571 82 228 7.85E-31 T 14-10-2018 LH59_23795 678a2aaa42a29d4fd59f506d2db32e02 231 Pfam PF00805 Pentapeptide repeats (8 copies) 93 125 3.9E-5 T 14-10-2018 IPR001646 Pentapeptide repeat LH59_23795 678a2aaa42a29d4fd59f506d2db32e02 231 Gene3D G3DSA:2.160.20.100 19 75 3.3E-5 T 14-10-2018 LH59_23795 678a2aaa42a29d4fd59f506d2db32e02 231 Gene3D G3DSA:2.160.20.100 76 231 1.4E-31 T 14-10-2018 LH59_19625 1aaabc0112806ee872481876a85b1bfd 320 SUPERFAMILY SSF51735 8 187 7.6E-44 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_19625 1aaabc0112806ee872481876a85b1bfd 320 Gene3D G3DSA:3.40.50.720 3 190 6.4E-54 T 14-10-2018 LH59_19625 1aaabc0112806ee872481876a85b1bfd 320 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 10 185 1.5E-46 T 14-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 LH59_19625 1aaabc0112806ee872481876a85b1bfd 320 Gene3D G3DSA:1.10.1040.10 191 315 1.3E-41 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 LH59_19625 1aaabc0112806ee872481876a85b1bfd 320 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 187 211 - T 14-10-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 LH59_19625 1aaabc0112806ee872481876a85b1bfd 320 SUPERFAMILY SSF48179 190 262 4.0E-14 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 LH59_19625 1aaabc0112806ee872481876a85b1bfd 320 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 190 280 7.2E-16 T 14-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 LH59_14610 d15d3ec1110a65cdc169abf6325c6ee7 536 Pfam PF03929 PepSY-associated TM region 2 377 4.0E-61 T 14-10-2018 IPR005625 PepSY-associated TM protein LH59_04165 0fd4fbbe554ab748d3957df785b37ccf 566 Pfam PF13193 AMP-binding enzyme C-terminal domain 472 546 1.6E-19 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain LH59_04165 0fd4fbbe554ab748d3957df785b37ccf 566 Gene3D G3DSA:3.30.300.310 460 561 3.2E-30 T 14-10-2018 LH59_04165 0fd4fbbe554ab748d3957df785b37ccf 566 Pfam PF00501 AMP-binding enzyme 30 463 2.4E-108 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 LH59_04165 0fd4fbbe554ab748d3957df785b37ccf 566 SUPERFAMILY SSF56801 22 557 5.23E-149 T 14-10-2018 LH59_04165 0fd4fbbe554ab748d3957df785b37ccf 566 ProSitePatterns PS00455 Putative AMP-binding domain signature. 210 221 - T 14-10-2018 IPR020845 AMP-binding, conserved site LH59_04165 0fd4fbbe554ab748d3957df785b37ccf 566 Gene3D G3DSA:3.40.50.12780 12 459 6.1E-115 T 14-10-2018 LH59_22220 4b2fb77b0a4b4969bea20024b716255f 415 SUPERFAMILY SSF63380 127 268 1.35E-38 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel LH59_22220 4b2fb77b0a4b4969bea20024b716255f 415 Gene3D G3DSA:2.40.30.10 123 260 1.2E-40 T 14-10-2018 LH59_22220 4b2fb77b0a4b4969bea20024b716255f 415 TIGRFAM TIGR03224 benzo_boxA: benzoyl-CoA oxygenase/reductase, BoxA protein 9 415 4.0E-220 T 14-10-2018 IPR017634 Benzoyl-CoA oxygenase/reductase, BoxA protein KEGG: 00362+1.14.13.208|MetaCyc: PWY-1361 LH59_22220 4b2fb77b0a4b4969bea20024b716255f 415 Pfam PF00175 Oxidoreductase NAD-binding domain 276 382 2.4E-12 T 14-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 LH59_22220 4b2fb77b0a4b4969bea20024b716255f 415 SUPERFAMILY SSF54862 14 68 7.54E-19 T 14-10-2018 LH59_22220 4b2fb77b0a4b4969bea20024b716255f 415 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 369 377 2.4E-17 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 LH59_22220 4b2fb77b0a4b4969bea20024b716255f 415 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 275 294 2.4E-17 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 LH59_22220 4b2fb77b0a4b4969bea20024b716255f 415 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 345 361 2.4E-17 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 LH59_22220 4b2fb77b0a4b4969bea20024b716255f 415 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 303 312 2.4E-17 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 LH59_22220 4b2fb77b0a4b4969bea20024b716255f 415 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 180 190 2.4E-17 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 LH59_22220 4b2fb77b0a4b4969bea20024b716255f 415 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 203 210 2.4E-17 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 LH59_22220 4b2fb77b0a4b4969bea20024b716255f 415 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 239 248 2.4E-17 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 LH59_22220 4b2fb77b0a4b4969bea20024b716255f 415 PIRSF PIRSF501177 1 415 7.3E-224 T 14-10-2018 IPR017634 Benzoyl-CoA oxygenase/reductase, BoxA protein KEGG: 00362+1.14.13.208|MetaCyc: PWY-1361 LH59_22220 4b2fb77b0a4b4969bea20024b716255f 415 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 49 60 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site LH59_22220 4b2fb77b0a4b4969bea20024b716255f 415 PIRSF PIRSF000361 73 415 4.8E-70 T 14-10-2018 IPR015701 Ferredoxin--NADP reductase GO:0016491|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 LH59_22220 4b2fb77b0a4b4969bea20024b716255f 415 SUPERFAMILY SSF52343 264 415 4.06E-33 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain LH59_22220 4b2fb77b0a4b4969bea20024b716255f 415 Gene3D G3DSA:3.30.70.20 13 65 2.6E-12 T 14-10-2018 LH59_22220 4b2fb77b0a4b4969bea20024b716255f 415 Gene3D G3DSA:3.40.50.80 261 415 6.1E-33 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain LH59_22220 4b2fb77b0a4b4969bea20024b716255f 415 Pfam PF00970 Oxidoreductase FAD-binding domain 200 263 1.6E-4 T 14-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 LH59_22220 4b2fb77b0a4b4969bea20024b716255f 415 Pfam PF00037 4Fe-4S binding domain 15 36 1.2E-6 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain LH59_22220 4b2fb77b0a4b4969bea20024b716255f 415 Pfam PF00037 4Fe-4S binding domain 42 64 9.5E-5 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain LH59_12065 7deaa559f8958385f5ef69fc41dfca7b 532 Pfam PF01266 FAD dependent oxidoreductase 27 386 1.2E-57 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 LH59_12065 7deaa559f8958385f5ef69fc41dfca7b 532 Gene3D G3DSA:1.10.8.870 424 530 4.2E-18 T 14-10-2018 IPR038299 Alpha-glycerophosphate oxidase, C-terminal domain superfamily KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 LH59_12065 7deaa559f8958385f5ef69fc41dfca7b 532 SUPERFAMILY SSF51905 26 352 1.73E-40 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_12065 7deaa559f8958385f5ef69fc41dfca7b 532 Gene3D G3DSA:3.50.50.60 27 394 8.5E-133 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_12065 7deaa559f8958385f5ef69fc41dfca7b 532 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 408 513 1.9E-15 T 14-10-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 LH59_12065 7deaa559f8958385f5ef69fc41dfca7b 532 Gene3D G3DSA:3.30.9.10 104 351 8.5E-133 T 14-10-2018 LH59_12065 7deaa559f8958385f5ef69fc41dfca7b 532 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 380 390 - T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 LH59_12065 7deaa559f8958385f5ef69fc41dfca7b 532 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 344 350 3.5E-29 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 LH59_12065 7deaa559f8958385f5ef69fc41dfca7b 532 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 55 67 3.5E-29 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 LH59_12065 7deaa559f8958385f5ef69fc41dfca7b 532 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 26 38 3.5E-29 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 LH59_12065 7deaa559f8958385f5ef69fc41dfca7b 532 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 100 112 3.5E-29 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 LH59_12065 7deaa559f8958385f5ef69fc41dfca7b 532 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 39 49 3.5E-29 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 LH59_12065 7deaa559f8958385f5ef69fc41dfca7b 532 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 375 387 3.5E-29 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 LH59_21980 322c24e656ae490462f7dbe3a07a3f71 214 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 200 8.8E-61 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 LH59_21980 322c24e656ae490462f7dbe3a07a3f71 214 SMART SM00855 3 161 2.2E-21 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 LH59_21980 322c24e656ae490462f7dbe3a07a3f71 214 Gene3D G3DSA:3.40.50.1240 1 211 2.5E-57 T 14-10-2018 IPR029033 Histidine phosphatase superfamily LH59_21980 322c24e656ae490462f7dbe3a07a3f71 214 SUPERFAMILY SSF53254 1 205 1.28E-56 T 14-10-2018 IPR029033 Histidine phosphatase superfamily LH59_21980 322c24e656ae490462f7dbe3a07a3f71 214 PIRSF PIRSF000709 1 119 7.7E-10 T 14-10-2018 LH59_10955 39eb4112772c380355e2ee2c862f39f9 144 Gene3D G3DSA:1.10.1660.10 1 127 1.8E-33 T 14-10-2018 LH59_10955 39eb4112772c380355e2ee2c862f39f9 144 TIGRFAM TIGR02047 CadR-PbrR: Cd(II)/Pb(II)-responsive transcriptional regulator 1 128 2.9E-48 T 14-10-2018 IPR011791 Cd(II)/Pb(II)-responsive transcriptional regulator GO:0003677|GO:0003700|GO:0045893|GO:0046872 LH59_10955 39eb4112772c380355e2ee2c862f39f9 144 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 1.8E-11 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LH59_10955 39eb4112772c380355e2ee2c862f39f9 144 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 1.8E-11 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LH59_10955 39eb4112772c380355e2ee2c862f39f9 144 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 1.8E-11 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LH59_10955 39eb4112772c380355e2ee2c862f39f9 144 SUPERFAMILY SSF46955 1 113 1.25E-32 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily LH59_10955 39eb4112772c380355e2ee2c862f39f9 144 SMART SM00422 1 70 3.2E-24 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LH59_10955 39eb4112772c380355e2ee2c862f39f9 144 Pfam PF00376 MerR family regulatory protein 2 39 2.5E-15 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LH59_10955 39eb4112772c380355e2ee2c862f39f9 144 Pfam PF09278 MerR, DNA binding 44 108 1.1E-18 T 14-10-2018 IPR015358 Transcription regulator MerR, DNA binding LH59_00390 7daffc665597f8ebeb181752a4315ba4 260 SMART SM00062 35 255 2.3E-42 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_00390 7daffc665597f8ebeb181752a4315ba4 260 Gene3D G3DSA:3.40.190.10 30 247 1.8E-54 T 14-10-2018 LH59_00390 7daffc665597f8ebeb181752a4315ba4 260 SUPERFAMILY SSF53850 7 255 3.3E-56 T 14-10-2018 LH59_00390 7daffc665597f8ebeb181752a4315ba4 260 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 36 253 4.4E-50 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_00390 7daffc665597f8ebeb181752a4315ba4 260 Gene3D G3DSA:3.40.190.10 122 213 1.8E-54 T 14-10-2018 LH59_03460 399be261c992504e38998ac4c94d6111 509 Pfam PF04293 SpoVR like protein 18 448 2.1E-172 T 14-10-2018 IPR007390 Sporulation stage V, protein R LH59_25685 d5dddd434f48e563ebd0bbcacf137ec7 286 SUPERFAMILY SSF51621 10 283 4.93E-91 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 LH59_25685 d5dddd434f48e563ebd0bbcacf137ec7 286 Pfam PF13714 Phosphoenolpyruvate phosphomutase 16 252 1.6E-56 T 14-10-2018 LH59_25685 d5dddd434f48e563ebd0bbcacf137ec7 286 Gene3D G3DSA:3.20.20.60 2 286 3.1E-98 T 14-10-2018 LH59_25685 d5dddd434f48e563ebd0bbcacf137ec7 286 ProSitePatterns PS00161 Isocitrate lyase signature. 119 124 - T 14-10-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824 LH59_26725 c73632b77165cdf010a1e248d1019beb 191 SUPERFAMILY SSF46689 4 72 7.09E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_26725 c73632b77165cdf010a1e248d1019beb 191 SUPERFAMILY SSF48498 83 181 1.56E-8 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily LH59_26725 c73632b77165cdf010a1e248d1019beb 191 Gene3D G3DSA:1.10.357.10 7 190 2.7E-47 T 14-10-2018 LH59_26725 c73632b77165cdf010a1e248d1019beb 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 56 7.4E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_13735 45b44d721ea8e78fbeb65c39e59a98db 208 Pfam PF14497 Glutathione S-transferase, C-terminal domain 123 203 1.4E-9 T 14-10-2018 IPR004046 Glutathione S-transferase, C-terminal LH59_13735 45b44d721ea8e78fbeb65c39e59a98db 208 Pfam PF02798 Glutathione S-transferase, N-terminal domain 5 75 1.1E-15 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 LH59_13735 45b44d721ea8e78fbeb65c39e59a98db 208 Gene3D G3DSA:3.40.30.10 4 87 3.0E-21 T 14-10-2018 LH59_13735 45b44d721ea8e78fbeb65c39e59a98db 208 SUPERFAMILY SSF47616 83 203 4.87E-22 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily LH59_13735 45b44d721ea8e78fbeb65c39e59a98db 208 Gene3D G3DSA:1.20.1050.10 88 195 8.1E-42 T 14-10-2018 LH59_13735 45b44d721ea8e78fbeb65c39e59a98db 208 SUPERFAMILY SSF52833 2 85 7.78E-18 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_15425 54fafc0b8069e422ba3abb98928d24af 897 Gene3D G3DSA:2.40.50.230 400 512 6.1E-38 T 14-10-2018 IPR037026 Vgr protein, OB-fold domain superfamily LH59_15425 54fafc0b8069e422ba3abb98928d24af 897 TIGRFAM TIGR03361 VI_Rhs_Vgr: type VI secretion system Vgr family protein 24 513 1.3E-108 T 14-10-2018 IPR017847 Type VI secretion system, RhsGE-associated Vgr family subset LH59_15425 54fafc0b8069e422ba3abb98928d24af 897 Gene3D G3DSA:2.30.110.50 27 354 8.2E-98 T 14-10-2018 LH59_15425 54fafc0b8069e422ba3abb98928d24af 897 SUPERFAMILY SSF69255 406 508 8.37E-25 T 14-10-2018 LH59_15425 54fafc0b8069e422ba3abb98928d24af 897 Gene3D G3DSA:3.30.1920.30 245 310 8.2E-98 T 14-10-2018 LH59_15425 54fafc0b8069e422ba3abb98928d24af 897 TIGRFAM TIGR01646 vgr_GE: Rhs element Vgr protein 37 512 6.8E-90 T 14-10-2018 IPR006533 Type VI secretion system, RhsGE-associated Vgr protein LH59_15425 54fafc0b8069e422ba3abb98928d24af 897 Pfam PF10106 Uncharacterized protein conserved in bacteria (DUF2345) 710 866 1.7E-32 T 14-10-2018 IPR018769 Domain of unknown function DUF2345, Vgr C-terminal LH59_15425 54fafc0b8069e422ba3abb98928d24af 897 Gene3D G3DSA:3.55.50.10 114 212 8.2E-98 T 14-10-2018 LH59_15425 54fafc0b8069e422ba3abb98928d24af 897 SUPERFAMILY SSF69279 227 395 4.93E-23 T 14-10-2018 LH59_15425 54fafc0b8069e422ba3abb98928d24af 897 Pfam PF05954 Phage late control gene D protein (GPD) 43 354 2.4E-88 T 14-10-2018 LH59_15425 54fafc0b8069e422ba3abb98928d24af 897 SUPERFAMILY SSF69279 25 208 2.21E-50 T 14-10-2018 LH59_15425 54fafc0b8069e422ba3abb98928d24af 897 Pfam PF13296 Putative type VI secretion system Rhs element Vgr 564 668 2.7E-28 T 14-10-2018 IPR028244 Putative type VI secretion system, Rhs element associated Vgr domain LH59_27130 e154595125d8d2b416dfbd44a9f75d10 303 Pfam PF01678 Diaminopimelate epimerase 11 130 3.1E-32 T 14-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 LH59_27130 e154595125d8d2b416dfbd44a9f75d10 303 Pfam PF01678 Diaminopimelate epimerase 172 282 3.4E-23 T 14-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 LH59_27130 e154595125d8d2b416dfbd44a9f75d10 303 Gene3D G3DSA:3.10.310.10 123 279 3.1E-93 T 14-10-2018 LH59_27130 e154595125d8d2b416dfbd44a9f75d10 303 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 72 86 - T 14-10-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 LH59_27130 e154595125d8d2b416dfbd44a9f75d10 303 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 9 292 36.468 T 14-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 LH59_27130 e154595125d8d2b416dfbd44a9f75d10 303 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 10 290 8.9E-82 T 14-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 LH59_27130 e154595125d8d2b416dfbd44a9f75d10 303 Gene3D G3DSA:3.10.310.10 11 288 3.1E-93 T 14-10-2018 LH59_27130 e154595125d8d2b416dfbd44a9f75d10 303 SUPERFAMILY SSF54506 9 292 7.69E-47 T 14-10-2018 LH59_14585 5587c02544547de1b94f7f7b99b330f1 1025 SUPERFAMILY SSF82866 290 490 1.23E-45 T 14-10-2018 LH59_14585 5587c02544547de1b94f7f7b99b330f1 1025 SUPERFAMILY SSF82714 183 266 3.66E-17 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_14585 5587c02544547de1b94f7f7b99b330f1 1025 Gene3D G3DSA:3.30.2090.10 179 269 1.3E-290 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_14585 5587c02544547de1b94f7f7b99b330f1 1025 Gene3D G3DSA:3.30.70.1430 550 645 1.3E-290 T 14-10-2018 LH59_14585 5587c02544547de1b94f7f7b99b330f1 1025 Pfam PF00873 AcrB/AcrD/AcrF family 5 1006 0.0 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_14585 5587c02544547de1b94f7f7b99b330f1 1025 SUPERFAMILY SSF82693 40 131 9.94E-22 T 14-10-2018 LH59_14585 5587c02544547de1b94f7f7b99b330f1 1025 SUPERFAMILY SSF82866 809 1007 4.05E-43 T 14-10-2018 LH59_14585 5587c02544547de1b94f7f7b99b330f1 1025 Gene3D G3DSA:3.30.70.1440 646 844 1.3E-290 T 14-10-2018 LH59_14585 5587c02544547de1b94f7f7b99b330f1 1025 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 1.3E-77 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_14585 5587c02544547de1b94f7f7b99b330f1 1025 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 1.3E-77 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_14585 5587c02544547de1b94f7f7b99b330f1 1025 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.3E-77 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_14585 5587c02544547de1b94f7f7b99b330f1 1025 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 1.3E-77 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_14585 5587c02544547de1b94f7f7b99b330f1 1025 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.3E-77 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_14585 5587c02544547de1b94f7f7b99b330f1 1025 PRINTS PR00702 Acriflavin resistance protein family signature 602 616 1.3E-77 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_14585 5587c02544547de1b94f7f7b99b330f1 1025 PRINTS PR00702 Acriflavin resistance protein family signature 535 552 1.3E-77 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_14585 5587c02544547de1b94f7f7b99b330f1 1025 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 1.3E-77 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_14585 5587c02544547de1b94f7f7b99b330f1 1025 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 1.3E-77 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_14585 5587c02544547de1b94f7f7b99b330f1 1025 SUPERFAMILY SSF82714 699 783 1.44E-19 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_14585 5587c02544547de1b94f7f7b99b330f1 1025 Gene3D G3DSA:3.30.70.1320 133 326 1.3E-290 T 14-10-2018 LH59_14585 5587c02544547de1b94f7f7b99b330f1 1025 SUPERFAMILY SSF82693 548 645 1.08E-14 T 14-10-2018 LH59_14585 5587c02544547de1b94f7f7b99b330f1 1025 Gene3D G3DSA:1.20.1640.10 501 1002 1.3E-290 T 14-10-2018 LH59_14585 5587c02544547de1b94f7f7b99b330f1 1025 SUPERFAMILY SSF82693 659 831 3.14E-7 T 14-10-2018 LH59_14585 5587c02544547de1b94f7f7b99b330f1 1025 SUPERFAMILY SSF82693 136 324 9.07E-24 T 14-10-2018 LH59_14585 5587c02544547de1b94f7f7b99b330f1 1025 Gene3D G3DSA:3.30.70.1430 40 794 1.3E-290 T 14-10-2018 LH59_14585 5587c02544547de1b94f7f7b99b330f1 1025 Gene3D G3DSA:1.20.1640.10 10 500 1.3E-290 T 14-10-2018 LH59_14585 5587c02544547de1b94f7f7b99b330f1 1025 Gene3D G3DSA:3.30.2090.10 698 786 1.3E-290 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_24570 cc4251575904ba2fb8fb5acfc897c217 275 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 114 1.2E-27 T 14-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 LH59_24570 cc4251575904ba2fb8fb5acfc897c217 275 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 133 222 7.5E-20 T 14-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 LH59_24570 cc4251575904ba2fb8fb5acfc897c217 275 ProSitePatterns PS01242 Zinc finger FPG-type signature. 249 273 - T 14-10-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 LH59_24570 cc4251575904ba2fb8fb5acfc897c217 275 SMART SM00898 2 115 1.5E-45 T 14-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 LH59_24570 cc4251575904ba2fb8fb5acfc897c217 275 SUPERFAMILY SSF46946 134 225 1.44E-25 T 14-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 LH59_24570 cc4251575904ba2fb8fb5acfc897c217 275 Gene3D G3DSA:3.20.190.10 2 126 1.3E-32 T 14-10-2018 IPR035937 MutM-like, N-terminal LH59_24570 cc4251575904ba2fb8fb5acfc897c217 275 Pfam PF06827 Zinc finger found in FPG and IleRS 246 274 1.5E-12 T 14-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 LH59_24570 cc4251575904ba2fb8fb5acfc897c217 275 SMART SM01232 133 225 5.9E-39 T 14-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 LH59_24570 cc4251575904ba2fb8fb5acfc897c217 275 SUPERFAMILY SSF81624 2 142 1.31E-37 T 14-10-2018 IPR035937 MutM-like, N-terminal LH59_24570 cc4251575904ba2fb8fb5acfc897c217 275 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 274 39.183 T 14-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 LH59_24570 cc4251575904ba2fb8fb5acfc897c217 275 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 273 4.9E-82 T 14-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 LH59_24570 cc4251575904ba2fb8fb5acfc897c217 275 SUPERFAMILY SSF57716 221 274 3.33E-16 T 14-10-2018 LH59_24570 cc4251575904ba2fb8fb5acfc897c217 275 Gene3D G3DSA:1.10.8.50 143 274 1.5E-43 T 14-10-2018 LH59_14850 2430933001d18ead534b1ffcb393f9fa 220 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 2 176 2.6E-31 T 14-10-2018 IPR001303 Class II aldolase/adducin N-terminal LH59_14850 2430933001d18ead534b1ffcb393f9fa 220 Gene3D G3DSA:3.40.225.10 1 220 2.5E-70 T 14-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily LH59_14850 2430933001d18ead534b1ffcb393f9fa 220 SMART SM01007 1 177 2.4E-17 T 14-10-2018 IPR001303 Class II aldolase/adducin N-terminal LH59_14850 2430933001d18ead534b1ffcb393f9fa 220 SUPERFAMILY SSF53639 10 205 1.51E-35 T 14-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily LH59_04415 08d6a9353f04b6defbff860eec518517 378 Gene3D G3DSA:3.40.640.10 12 259 7.0E-84 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_04415 08d6a9353f04b6defbff860eec518517 378 Gene3D G3DSA:3.90.1150.10 4 347 7.0E-84 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_04415 08d6a9353f04b6defbff860eec518517 378 PIRSF PIRSF000524 1 371 1.2E-51 T 14-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 LH59_04415 08d6a9353f04b6defbff860eec518517 378 SUPERFAMILY SSF53383 2 362 3.06E-71 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_04415 08d6a9353f04b6defbff860eec518517 378 Pfam PF00266 Aminotransferase class-V 28 298 1.3E-21 T 14-10-2018 IPR000192 Aminotransferase class V domain LH59_04415 08d6a9353f04b6defbff860eec518517 378 Hamap MF_01376 2-aminoethylphosphonate--pyruvate transaminase [phnW]. 1 367 122.728 T 14-10-2018 IPR012703 2-aminoethylphosphonate--pyruvate transaminase GO:0019700|GO:0047304 KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832 LH59_28035 7cd9f87daf20ed567261fb4ca629ca45 387 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 180 208 - T 14-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 LH59_28035 7cd9f87daf20ed567261fb4ca629ca45 387 Gene3D G3DSA:3.40.50.1970 2 191 3.8E-56 T 14-10-2018 LH59_28035 7cd9f87daf20ed567261fb4ca629ca45 387 SUPERFAMILY SSF56796 6 385 2.09E-123 T 14-10-2018 LH59_28035 7cd9f87daf20ed567261fb4ca629ca45 387 Pfam PF00465 Iron-containing alcohol dehydrogenase 11 374 1.1E-116 T 14-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 LH59_28035 7cd9f87daf20ed567261fb4ca629ca45 387 Gene3D G3DSA:1.20.1090.10 193 386 3.2E-55 T 14-10-2018 LH59_10290 332e69f165a6a1096ace8a2618272c5e 124 Gene3D G3DSA:3.40.30.10 20 120 6.0E-13 T 14-10-2018 LH59_10290 332e69f165a6a1096ace8a2618272c5e 124 ProSitePatterns PS00195 Glutaredoxin active site. 45 61 - T 14-10-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 LH59_10290 332e69f165a6a1096ace8a2618272c5e 124 Pfam PF13417 Glutathione S-transferase, N-terminal domain 45 122 6.1E-13 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 LH59_10290 332e69f165a6a1096ace8a2618272c5e 124 SUPERFAMILY SSF52833 44 122 4.42E-19 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_02805 a9d52befc4d73d21d03ed22150062ab1 1036 Gene3D G3DSA:1.20.1640.10 10 505 6.8E-297 T 14-10-2018 LH59_02805 a9d52befc4d73d21d03ed22150062ab1 1036 SUPERFAMILY SSF82693 558 654 3.98E-16 T 14-10-2018 LH59_02805 a9d52befc4d73d21d03ed22150062ab1 1036 SUPERFAMILY SSF82693 669 837 2.49E-9 T 14-10-2018 LH59_02805 a9d52befc4d73d21d03ed22150062ab1 1036 SUPERFAMILY SSF82714 707 789 3.01E-14 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_02805 a9d52befc4d73d21d03ed22150062ab1 1036 Gene3D G3DSA:3.30.70.1320 135 326 6.8E-297 T 14-10-2018 LH59_02805 a9d52befc4d73d21d03ed22150062ab1 1036 SUPERFAMILY SSF82693 136 324 2.09E-21 T 14-10-2018 LH59_02805 a9d52befc4d73d21d03ed22150062ab1 1036 Gene3D G3DSA:3.30.70.1430 560 653 6.8E-297 T 14-10-2018 LH59_02805 a9d52befc4d73d21d03ed22150062ab1 1036 Gene3D G3DSA:3.30.2090.10 705 793 6.8E-297 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_02805 a9d52befc4d73d21d03ed22150062ab1 1036 Gene3D G3DSA:3.30.70.1440 654 852 6.8E-297 T 14-10-2018 LH59_02805 a9d52befc4d73d21d03ed22150062ab1 1036 SUPERFAMILY SSF82866 815 1015 3.79E-41 T 14-10-2018 LH59_02805 a9d52befc4d73d21d03ed22150062ab1 1036 SUPERFAMILY SSF82866 290 490 8.5E-49 T 14-10-2018 LH59_02805 a9d52befc4d73d21d03ed22150062ab1 1036 SUPERFAMILY SSF82714 183 266 4.97E-17 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_02805 a9d52befc4d73d21d03ed22150062ab1 1036 Gene3D G3DSA:3.30.2090.10 179 269 6.8E-297 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_02805 a9d52befc4d73d21d03ed22150062ab1 1036 Gene3D G3DSA:3.30.70.1430 40 801 6.8E-297 T 14-10-2018 LH59_02805 a9d52befc4d73d21d03ed22150062ab1 1036 SUPERFAMILY SSF82693 40 134 3.66E-23 T 14-10-2018 LH59_02805 a9d52befc4d73d21d03ed22150062ab1 1036 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 9.6E-82 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_02805 a9d52befc4d73d21d03ed22150062ab1 1036 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 9.6E-82 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_02805 a9d52befc4d73d21d03ed22150062ab1 1036 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 9.6E-82 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_02805 a9d52befc4d73d21d03ed22150062ab1 1036 PRINTS PR00702 Acriflavin resistance protein family signature 545 562 9.6E-82 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_02805 a9d52befc4d73d21d03ed22150062ab1 1036 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 9.6E-82 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_02805 a9d52befc4d73d21d03ed22150062ab1 1036 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 9.6E-82 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_02805 a9d52befc4d73d21d03ed22150062ab1 1036 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 9.6E-82 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_02805 a9d52befc4d73d21d03ed22150062ab1 1036 PRINTS PR00702 Acriflavin resistance protein family signature 609 623 9.6E-82 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_02805 a9d52befc4d73d21d03ed22150062ab1 1036 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 9.6E-82 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_02805 a9d52befc4d73d21d03ed22150062ab1 1036 Pfam PF00873 AcrB/AcrD/AcrF family 6 1013 0.0 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_02805 a9d52befc4d73d21d03ed22150062ab1 1036 Gene3D G3DSA:1.20.1640.10 506 1010 6.8E-297 T 14-10-2018 LH59_24865 372dce0cad0b8a0ea0ef9e1cd6a072bf 412 Pfam PF00990 Diguanylate cyclase, GGDEF domain 357 400 1.4E-5 T 14-10-2018 IPR000160 GGDEF domain LH59_24865 372dce0cad0b8a0ea0ef9e1cd6a072bf 412 Pfam PF00990 Diguanylate cyclase, GGDEF domain 228 334 2.7E-22 T 14-10-2018 IPR000160 GGDEF domain LH59_24865 372dce0cad0b8a0ea0ef9e1cd6a072bf 412 SMART SM00267 213 404 5.2E-40 T 14-10-2018 IPR000160 GGDEF domain LH59_24865 372dce0cad0b8a0ea0ef9e1cd6a072bf 412 Gene3D G3DSA:3.30.70.270 220 404 6.6E-48 T 14-10-2018 LH59_24865 372dce0cad0b8a0ea0ef9e1cd6a072bf 412 SUPERFAMILY SSF55073 233 404 1.02E-37 T 14-10-2018 IPR029787 Nucleotide cyclase LH59_24865 372dce0cad0b8a0ea0ef9e1cd6a072bf 412 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 226 336 1.1E-25 T 14-10-2018 IPR000160 GGDEF domain LH59_24165 b568e3757750d19d5916514c816c8dce 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 70 1.5E-14 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_24165 b568e3757750d19d5916514c816c8dce 303 Pfam PF03466 LysR substrate binding domain 98 295 2.7E-40 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_24165 b568e3757750d19d5916514c816c8dce 303 Gene3D G3DSA:3.40.190.290 99 297 4.0E-45 T 14-10-2018 LH59_24165 b568e3757750d19d5916514c816c8dce 303 SUPERFAMILY SSF46785 8 86 6.4E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_24165 b568e3757750d19d5916514c816c8dce 303 SUPERFAMILY SSF53850 99 298 1.45E-37 T 14-10-2018 LH59_24165 b568e3757750d19d5916514c816c8dce 303 Gene3D G3DSA:1.10.10.10 8 97 5.2E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_17235 5ae8a5cd0dda6662516d90d3bc6305cc 436 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 160 239 3.5E-13 T 14-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain LH59_17235 5ae8a5cd0dda6662516d90d3bc6305cc 436 PIRSF PIRSF003095 1 436 3.2E-126 T 14-10-2018 IPR005215 Trigger factor GO:0015031 LH59_17235 5ae8a5cd0dda6662516d90d3bc6305cc 436 TIGRFAM TIGR00115 tig: trigger factor 11 416 9.0E-131 T 14-10-2018 IPR005215 Trigger factor GO:0015031 LH59_17235 5ae8a5cd0dda6662516d90d3bc6305cc 436 SUPERFAMILY SSF54534 103 243 9.73E-31 T 14-10-2018 LH59_17235 5ae8a5cd0dda6662516d90d3bc6305cc 436 Gene3D G3DSA:1.10.3120.10 117 422 4.5E-91 T 14-10-2018 IPR037041 Trigger factor, C-terminal domain superfamily GO:0006457|GO:0015031 LH59_17235 5ae8a5cd0dda6662516d90d3bc6305cc 436 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 265 418 2.0E-32 T 14-10-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 LH59_17235 5ae8a5cd0dda6662516d90d3bc6305cc 436 Gene3D G3DSA:3.10.50.40 151 248 4.5E-91 T 14-10-2018 LH59_17235 5ae8a5cd0dda6662516d90d3bc6305cc 436 Hamap MF_00303 Trigger factor [tig]. 1 423 20.226 T 14-10-2018 IPR005215 Trigger factor GO:0015031 LH59_17235 5ae8a5cd0dda6662516d90d3bc6305cc 436 SUPERFAMILY SSF102735 1 130 1.44E-30 T 14-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 LH59_17235 5ae8a5cd0dda6662516d90d3bc6305cc 436 Pfam PF05697 Bacterial trigger factor protein (TF) 1 143 3.8E-35 T 14-10-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 LH59_17235 5ae8a5cd0dda6662516d90d3bc6305cc 436 Gene3D G3DSA:3.30.70.1050 1 116 1.4E-30 T 14-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 LH59_17235 5ae8a5cd0dda6662516d90d3bc6305cc 436 SUPERFAMILY SSF109998 250 435 2.65E-44 T 14-10-2018 IPR027304 Trigger factor/SurA domain superfamily LH59_14445 65de6fd444b77479a4d0bd7a23d3fed4 370 SUPERFAMILY SSF56645 15 218 7.85E-29 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 LH59_14445 65de6fd444b77479a4d0bd7a23d3fed4 370 Gene3D G3DSA:2.40.110.10 125 222 3.7E-9 T 14-10-2018 LH59_14445 65de6fd444b77479a4d0bd7a23d3fed4 370 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 30 112 1.4E-6 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 LH59_14445 65de6fd444b77479a4d0bd7a23d3fed4 370 Gene3D G3DSA:1.10.540.10 13 112 4.5E-10 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 LH59_14370 39d642675605bbc9f40cda24a3eb4764 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 7.9E-27 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_14370 39d642675605bbc9f40cda24a3eb4764 294 SUPERFAMILY SSF46785 1 110 1.65E-25 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_14370 39d642675605bbc9f40cda24a3eb4764 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.2E-11 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_14370 39d642675605bbc9f40cda24a3eb4764 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.2E-11 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_14370 39d642675605bbc9f40cda24a3eb4764 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.2E-11 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_14370 39d642675605bbc9f40cda24a3eb4764 294 Pfam PF03466 LysR substrate binding domain 88 285 1.0E-37 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_14370 39d642675605bbc9f40cda24a3eb4764 294 SUPERFAMILY SSF53850 95 290 4.14E-34 T 14-10-2018 LH59_14370 39d642675605bbc9f40cda24a3eb4764 294 Gene3D G3DSA:1.10.10.10 1 92 2.8E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_14370 39d642675605bbc9f40cda24a3eb4764 294 Gene3D G3DSA:3.40.190.10 95 291 3.9E-64 T 14-10-2018 LH59_14370 39d642675605bbc9f40cda24a3eb4764 294 Gene3D G3DSA:3.40.190.10 163 267 3.9E-64 T 14-10-2018 LH59_13075 89edcd976a3d41f29dbb4be74b28e431 239 SMART SM00448 1 114 5.6E-21 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_13075 89edcd976a3d41f29dbb4be74b28e431 239 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 226 2.5E-14 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_13075 89edcd976a3d41f29dbb4be74b28e431 239 Gene3D G3DSA:1.10.10.10 131 233 7.5E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_13075 89edcd976a3d41f29dbb4be74b28e431 239 SMART SM00862 151 227 6.1E-10 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_13075 89edcd976a3d41f29dbb4be74b28e431 239 Pfam PF00072 Response regulator receiver domain 3 112 2.0E-17 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_13075 89edcd976a3d41f29dbb4be74b28e431 239 Gene3D G3DSA:3.40.50.2300 1 129 3.0E-21 T 14-10-2018 LH59_13075 89edcd976a3d41f29dbb4be74b28e431 239 SUPERFAMILY SSF46894 137 227 4.54E-15 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LH59_13075 89edcd976a3d41f29dbb4be74b28e431 239 SUPERFAMILY SSF52172 2 124 8.54E-27 T 14-10-2018 IPR011006 CheY-like superfamily LH59_05350 77c2903a335ed274fc32a69de819379d 390 Pfam PF05762 VWA domain containing CoxE-like protein 184 269 2.9E-7 T 14-10-2018 IPR008912 Uncharacterised protein family CoxE-like LH59_18075 8f363abab97d5eda201f1bff98b39650 283 TIGRFAM TIGR02298 HpaD_Fe: 3,4-dihydroxyphenylacetate 2,3-dioxygenase 1 281 2.6E-147 T 14-10-2018 IPR011984 3,4-dihydroxyphenylacetate 2,3-dioxygenase GO:0008687 KEGG: 00350+1.13.11.15 LH59_18075 8f363abab97d5eda201f1bff98b39650 283 Gene3D G3DSA:3.40.830.10 1 281 2.1E-83 T 14-10-2018 LH59_18075 8f363abab97d5eda201f1bff98b39650 283 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 7 279 3.6E-68 T 14-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 LH59_18075 8f363abab97d5eda201f1bff98b39650 283 SUPERFAMILY SSF53213 12 277 1.44E-52 T 14-10-2018 LH59_18345 957371005bee925e1a528fa7deb0c847 332 Gene3D G3DSA:3.40.190.150 37 322 2.0E-103 T 14-10-2018 LH59_18345 957371005bee925e1a528fa7deb0c847 332 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 57 327 9.7E-78 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_18345 957371005bee925e1a528fa7deb0c847 332 PIRSF PIRSF017082 1 332 1.3E-84 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_18345 957371005bee925e1a528fa7deb0c847 332 Gene3D G3DSA:3.40.190.10 134 257 2.0E-103 T 14-10-2018 LH59_18345 957371005bee925e1a528fa7deb0c847 332 SUPERFAMILY SSF53850 121 297 2.64E-14 T 14-10-2018 LH59_16505 37187ed00279527e26a84b5314d4ab5c 270 Gene3D G3DSA:1.10.10.60 160 269 5.9E-26 T 14-10-2018 LH59_16505 37187ed00279527e26a84b5314d4ab5c 270 Pfam PF12833 Helix-turn-helix domain 186 264 1.2E-22 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_16505 37187ed00279527e26a84b5314d4ab5c 270 SUPERFAMILY SSF52172 11 139 1.25E-37 T 14-10-2018 IPR011006 CheY-like superfamily LH59_16505 37187ed00279527e26a84b5314d4ab5c 270 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 217 259 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 LH59_16505 37187ed00279527e26a84b5314d4ab5c 270 SMART SM00342 180 263 2.2E-23 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_16505 37187ed00279527e26a84b5314d4ab5c 270 SMART SM00448 16 129 9.3E-37 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_16505 37187ed00279527e26a84b5314d4ab5c 270 SUPERFAMILY SSF46689 164 214 8.96E-5 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_16505 37187ed00279527e26a84b5314d4ab5c 270 Pfam PF00072 Response regulator receiver domain 18 128 7.6E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_16505 37187ed00279527e26a84b5314d4ab5c 270 SUPERFAMILY SSF46689 217 265 3.76E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_16505 37187ed00279527e26a84b5314d4ab5c 270 Gene3D G3DSA:3.40.50.2300 12 138 6.4E-35 T 14-10-2018 LH59_11255 409521eb7231cdee76e698c8dd5e26e2 590 SUPERFAMILY SSF51230 3 96 1.17E-22 T 14-10-2018 IPR011053 Single hybrid motif LH59_11255 409521eb7231cdee76e698c8dd5e26e2 590 Gene3D G3DSA:3.30.390.30 464 585 6.4E-49 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 LH59_11255 409521eb7231cdee76e698c8dd5e26e2 590 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 LH59_11255 409521eb7231cdee76e698c8dd5e26e2 590 Gene3D G3DSA:3.50.50.60 271 392 5.4E-118 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_11255 409521eb7231cdee76e698c8dd5e26e2 590 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 124 446 1.2E-55 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LH59_11255 409521eb7231cdee76e698c8dd5e26e2 590 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 465 573 3.3E-36 T 14-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 LH59_11255 409521eb7231cdee76e698c8dd5e26e2 590 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 526 541 4.2E-69 T 14-10-2018 LH59_11255 409521eb7231cdee76e698c8dd5e26e2 590 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 158 173 4.2E-69 T 14-10-2018 LH59_11255 409521eb7231cdee76e698c8dd5e26e2 590 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 294 319 4.2E-69 T 14-10-2018 LH59_11255 409521eb7231cdee76e698c8dd5e26e2 590 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 461 482 4.2E-69 T 14-10-2018 LH59_11255 409521eb7231cdee76e698c8dd5e26e2 590 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 259 268 4.2E-69 T 14-10-2018 LH59_11255 409521eb7231cdee76e698c8dd5e26e2 590 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 426 433 4.2E-69 T 14-10-2018 LH59_11255 409521eb7231cdee76e698c8dd5e26e2 590 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 125 147 4.2E-69 T 14-10-2018 LH59_11255 409521eb7231cdee76e698c8dd5e26e2 590 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 383 397 4.2E-69 T 14-10-2018 LH59_11255 409521eb7231cdee76e698c8dd5e26e2 590 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 548 568 4.2E-69 T 14-10-2018 LH59_11255 409521eb7231cdee76e698c8dd5e26e2 590 SUPERFAMILY SSF51905 121 456 6.79E-55 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_11255 409521eb7231cdee76e698c8dd5e26e2 590 SUPERFAMILY SSF55424 461 584 4.64E-41 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 LH59_11255 409521eb7231cdee76e698c8dd5e26e2 590 Pfam PF00364 Biotin-requiring enzyme 6 76 1.0E-19 T 14-10-2018 IPR000089 Biotin/lipoyl attachment LH59_11255 409521eb7231cdee76e698c8dd5e26e2 590 Gene3D G3DSA:2.40.50.100 4 81 6.4E-20 T 14-10-2018 LH59_11255 409521eb7231cdee76e698c8dd5e26e2 590 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 159 169 - T 14-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 LH59_11255 409521eb7231cdee76e698c8dd5e26e2 590 Gene3D G3DSA:3.50.50.60 124 451 5.4E-118 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_11255 409521eb7231cdee76e698c8dd5e26e2 590 PIRSF PIRSF000350 39 582 1.2E-88 T 14-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 LH59_11255 409521eb7231cdee76e698c8dd5e26e2 590 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 123 578 3.3E-148 T 14-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 LH59_11255 409521eb7231cdee76e698c8dd5e26e2 590 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 382 398 1.2E-38 T 14-10-2018 LH59_11255 409521eb7231cdee76e698c8dd5e26e2 590 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 294 312 1.2E-38 T 14-10-2018 LH59_11255 409521eb7231cdee76e698c8dd5e26e2 590 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 411 433 1.2E-38 T 14-10-2018 LH59_11255 409521eb7231cdee76e698c8dd5e26e2 590 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 126 145 1.2E-38 T 14-10-2018 LH59_11255 409521eb7231cdee76e698c8dd5e26e2 590 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 256 274 1.2E-38 T 14-10-2018 LH59_04040 7362670f32e0e9bc706ceb53c90605b1 397 Hamap MF_00913 Probable peptidoglycan glycosyltransferase FtsW [ftsW]. 23 396 38.98 T 14-10-2018 IPR013437 Probable peptidoglycan glycosyltransferase FtsW GO:0009252|GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 LH59_04040 7362670f32e0e9bc706ceb53c90605b1 397 Pfam PF01098 Cell cycle protein 30 389 3.1E-99 T 14-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 LH59_04040 7362670f32e0e9bc706ceb53c90605b1 397 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 28 387 9.4E-122 T 14-10-2018 IPR013437 Probable peptidoglycan glycosyltransferase FtsW GO:0009252|GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 LH59_11490 348bab8f38433fe5928fc1d233a02895 185 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 99 174 3.7E-34 T 14-10-2018 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 LH59_11490 348bab8f38433fe5928fc1d233a02895 185 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 102 172 6.8E-26 T 14-10-2018 IPR001543 Surface presentation of antigen (SpoA) LH59_11490 348bab8f38433fe5928fc1d233a02895 185 PRINTS PR00956 Flagellar motor switch protein FliN signature 119 135 5.2E-30 T 14-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 LH59_11490 348bab8f38433fe5928fc1d233a02895 185 PRINTS PR00956 Flagellar motor switch protein FliN signature 102 118 5.2E-30 T 14-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 LH59_11490 348bab8f38433fe5928fc1d233a02895 185 PRINTS PR00956 Flagellar motor switch protein FliN signature 135 148 5.2E-30 T 14-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 LH59_11490 348bab8f38433fe5928fc1d233a02895 185 PRINTS PR00956 Flagellar motor switch protein FliN signature 148 163 5.2E-30 T 14-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 LH59_11490 348bab8f38433fe5928fc1d233a02895 185 Gene3D G3DSA:2.30.330.10 92 183 3.0E-35 T 14-10-2018 IPR036429 SpoA-like superfamily LH59_11490 348bab8f38433fe5928fc1d233a02895 185 SUPERFAMILY SSF101801 100 181 1.83E-26 T 14-10-2018 IPR036429 SpoA-like superfamily LH59_16280 195ee52bdc67111eca34b25f8e615c66 239 Gene3D G3DSA:3.40.190.10 96 188 2.3E-20 T 14-10-2018 LH59_16280 195ee52bdc67111eca34b25f8e615c66 239 SUPERFAMILY SSF53850 12 227 1.25E-27 T 14-10-2018 LH59_16280 195ee52bdc67111eca34b25f8e615c66 239 SMART SM00062 10 229 2.3E-18 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_16280 195ee52bdc67111eca34b25f8e615c66 239 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 22 225 1.7E-17 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_16280 195ee52bdc67111eca34b25f8e615c66 239 Gene3D G3DSA:3.40.190.10 8 220 2.3E-20 T 14-10-2018 LH59_21640 563f28244b65368baa11de5df5d11a66 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.6E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_21640 563f28244b65368baa11de5df5d11a66 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.6E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_21640 563f28244b65368baa11de5df5d11a66 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.6E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_21640 563f28244b65368baa11de5df5d11a66 301 SUPERFAMILY SSF46785 1 85 5.93E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_21640 563f28244b65368baa11de5df5d11a66 301 Pfam PF03466 LysR substrate binding domain 88 292 2.9E-39 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_21640 563f28244b65368baa11de5df5d11a66 301 SUPERFAMILY SSF53850 90 290 3.69E-36 T 14-10-2018 LH59_21640 563f28244b65368baa11de5df5d11a66 301 Gene3D G3DSA:1.10.10.10 1 91 8.9E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_21640 563f28244b65368baa11de5df5d11a66 301 Gene3D G3DSA:3.40.190.290 92 295 2.0E-42 T 14-10-2018 LH59_21640 563f28244b65368baa11de5df5d11a66 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 5.1E-21 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_21480 0a91c68abbf72ad2c3ef65d412d525c4 290 SUPERFAMILY SSF51621 2 289 1.93E-74 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 LH59_21480 0a91c68abbf72ad2c3ef65d412d525c4 290 Pfam PF13714 Phosphoenolpyruvate phosphomutase 7 253 3.4E-69 T 14-10-2018 LH59_21480 0a91c68abbf72ad2c3ef65d412d525c4 290 TIGRFAM TIGR02321 Pphn_pyruv_hyd: phosphonopyruvate hydrolase 4 290 5.0E-153 T 14-10-2018 IPR012649 Phosphonopyruvate hydrolase KEGG: 00440+3.11.1.3 LH59_21480 0a91c68abbf72ad2c3ef65d412d525c4 290 Gene3D G3DSA:3.20.20.60 1 290 1.9E-91 T 14-10-2018 LH59_12755 a69f75d0638f849b6e47b7588f5238b3 305 SUPERFAMILY SSF46785 5 108 1.09E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_12755 a69f75d0638f849b6e47b7588f5238b3 305 Pfam PF03466 LysR substrate binding domain 95 292 1.3E-18 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_12755 a69f75d0638f849b6e47b7588f5238b3 305 SUPERFAMILY SSF53850 96 294 8.87E-23 T 14-10-2018 LH59_12755 a69f75d0638f849b6e47b7588f5238b3 305 Gene3D G3DSA:3.40.190.290 96 283 1.2E-8 T 14-10-2018 LH59_12755 a69f75d0638f849b6e47b7588f5238b3 305 Gene3D G3DSA:1.10.10.10 5 91 4.2E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_12755 a69f75d0638f849b6e47b7588f5238b3 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 6.7E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_02280 a44db629180311b122cc09d331499032 230 SMART SM00382 26 207 2.8E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_02280 a44db629180311b122cc09d331499032 230 Gene3D G3DSA:3.40.50.300 1 230 1.0E-54 T 14-10-2018 LH59_02280 a44db629180311b122cc09d331499032 230 SUPERFAMILY SSF52540 2 227 1.74E-53 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_02280 a44db629180311b122cc09d331499032 230 Pfam PF00005 ABC transporter 20 158 2.8E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_02280 a44db629180311b122cc09d331499032 230 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_24255 ec3e0705d3152798ce9ab26c9f325579 221 SMART SM00248 195 221 3300.0 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 LH59_24255 ec3e0705d3152798ce9ab26c9f325579 221 SMART SM00248 124 153 1.9 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 LH59_24255 ec3e0705d3152798ce9ab26c9f325579 221 SMART SM00248 157 191 4.7 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 LH59_24255 ec3e0705d3152798ce9ab26c9f325579 221 SMART SM00248 58 87 0.12 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 LH59_24255 ec3e0705d3152798ce9ab26c9f325579 221 SUPERFAMILY SSF48403 30 220 6.47E-43 T 14-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily LH59_24255 ec3e0705d3152798ce9ab26c9f325579 221 Pfam PF00023 Ankyrin repeat 58 89 0.0026 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 LH59_24255 ec3e0705d3152798ce9ab26c9f325579 221 Pfam PF12796 Ankyrin repeats (3 copies) 107 193 2.3E-8 T 14-10-2018 IPR020683 Ankyrin repeat-containing domain LH59_24255 ec3e0705d3152798ce9ab26c9f325579 221 Gene3D G3DSA:1.25.40.20 26 221 3.6E-49 T 14-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily LH59_04465 383ee282760c5c4eac74218f24f678a5 409 Pfam PF02515 CoA-transferase family III 7 385 1.3E-130 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 LH59_04465 383ee282760c5c4eac74218f24f678a5 409 SUPERFAMILY SSF89796 5 406 1.83E-141 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily LH59_04465 383ee282760c5c4eac74218f24f678a5 409 Gene3D G3DSA:3.40.50.10540 7 402 1.4E-142 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily LH59_04465 383ee282760c5c4eac74218f24f678a5 409 Gene3D G3DSA:3.30.1540.10 245 336 1.4E-142 T 14-10-2018 LH59_19445 50371d5d5f2ee03d346e935bef5098b7 432 Pfam PF01546 Peptidase family M20/M25/M40 102 422 1.1E-32 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 LH59_19445 50371d5d5f2ee03d346e935bef5098b7 432 SUPERFAMILY SSF53187 10 426 6.0E-57 T 14-10-2018 LH59_19445 50371d5d5f2ee03d346e935bef5098b7 432 SUPERFAMILY SSF55031 209 321 1.31E-13 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain LH59_19445 50371d5d5f2ee03d346e935bef5098b7 432 Gene3D G3DSA:3.40.630.10 31 426 1.5E-148 T 14-10-2018 LH59_19445 50371d5d5f2ee03d346e935bef5098b7 432 Pfam PF07687 Peptidase dimerisation domain 206 322 4.4E-18 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain LH59_19445 50371d5d5f2ee03d346e935bef5098b7 432 Gene3D G3DSA:3.30.70.360 209 338 1.5E-148 T 14-10-2018 LH59_19445 50371d5d5f2ee03d346e935bef5098b7 432 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 25 414 2.2E-93 T 14-10-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase LH59_00045 06ad2a6c6c2765263b3e8b0102964ce7 631 Gene3D G3DSA:3.10.310.70 87 197 1.8E-91 T 14-10-2018 LH59_00045 06ad2a6c6c2765263b3e8b0102964ce7 631 SUPERFAMILY SSF51556 67 499 3.74E-45 T 14-10-2018 IPR032466 Metal-dependent hydrolase LH59_00045 06ad2a6c6c2765263b3e8b0102964ce7 631 Gene3D G3DSA:3.20.20.140 68 499 1.8E-91 T 14-10-2018 LH59_00045 06ad2a6c6c2765263b3e8b0102964ce7 631 Pfam PF07969 Amidohydrolase family 58 540 1.5E-117 T 14-10-2018 IPR013108 Amidohydrolase 3 LH59_00045 06ad2a6c6c2765263b3e8b0102964ce7 631 SUPERFAMILY SSF51338 5 550 2.43E-23 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 LH59_00045 06ad2a6c6c2765263b3e8b0102964ce7 631 Gene3D G3DSA:2.30.40.10 15 515 1.8E-91 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 LH59_27045 ceed33479d056c36d3e9e3be7dc3f2ab 332 Gene3D G3DSA:3.40.190.150 33 326 1.4E-103 T 14-10-2018 LH59_27045 ceed33479d056c36d3e9e3be7dc3f2ab 332 SUPERFAMILY SSF53850 120 290 1.16E-9 T 14-10-2018 LH59_27045 ceed33479d056c36d3e9e3be7dc3f2ab 332 Gene3D G3DSA:3.40.190.10 131 254 1.4E-103 T 14-10-2018 LH59_27045 ceed33479d056c36d3e9e3be7dc3f2ab 332 PIRSF PIRSF017082 2 332 2.0E-80 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_27045 ceed33479d056c36d3e9e3be7dc3f2ab 332 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 328 2.1E-82 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_10040 73da073fa873524a125ac82f827a4f70 212 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 77 155 9.2E-14 T 14-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 LH59_10040 73da073fa873524a125ac82f827a4f70 212 SUPERFAMILY SSF56214 76 182 3.92E-20 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 LH59_10040 73da073fa873524a125ac82f827a4f70 212 Gene3D G3DSA:3.90.470.20 77 177 4.1E-16 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 LH59_10140 623282a4f75c33da03327595c691a5ad 236 Pfam PF00027 Cyclic nucleotide-binding domain 42 126 1.0E-11 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain LH59_10140 623282a4f75c33da03327595c691a5ad 236 SUPERFAMILY SSF51206 16 151 3.14E-23 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like LH59_10140 623282a4f75c33da03327595c691a5ad 236 Pfam PF13545 Crp-like helix-turn-helix domain 160 231 5.1E-12 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 LH59_10140 623282a4f75c33da03327595c691a5ad 236 Gene3D G3DSA:1.10.10.10 156 231 1.9E-13 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_10140 623282a4f75c33da03327595c691a5ad 236 SUPERFAMILY SSF46785 157 232 3.8E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_10140 623282a4f75c33da03327595c691a5ad 236 SMART SM00100 22 143 0.0017 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain LH59_10140 623282a4f75c33da03327595c691a5ad 236 Gene3D G3DSA:2.60.120.10 6 155 5.4E-18 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_20870 800d1986eb0d803bca9305f5baf98659 531 Gene3D G3DSA:1.10.246.130 243 352 1.9E-31 T 14-10-2018 LH59_20870 800d1986eb0d803bca9305f5baf98659 531 Pfam PF01019 Gamma-glutamyltranspeptidase 37 526 1.0E-157 T 14-10-2018 LH59_20870 800d1986eb0d803bca9305f5baf98659 531 SUPERFAMILY SSF56235 9 531 4.24E-175 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal LH59_20870 800d1986eb0d803bca9305f5baf98659 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 350 368 3.4E-41 T 14-10-2018 LH59_20870 800d1986eb0d803bca9305f5baf98659 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 44 69 3.4E-41 T 14-10-2018 LH59_20870 800d1986eb0d803bca9305f5baf98659 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 111 129 3.4E-41 T 14-10-2018 LH59_20870 800d1986eb0d803bca9305f5baf98659 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 129 148 3.4E-41 T 14-10-2018 LH59_20870 800d1986eb0d803bca9305f5baf98659 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 374 392 3.4E-41 T 14-10-2018 LH59_20870 800d1986eb0d803bca9305f5baf98659 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 429 446 3.4E-41 T 14-10-2018 LH59_20870 800d1986eb0d803bca9305f5baf98659 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 256 275 3.4E-41 T 14-10-2018 LH59_20870 800d1986eb0d803bca9305f5baf98659 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 405 420 3.4E-41 T 14-10-2018 LH59_20870 800d1986eb0d803bca9305f5baf98659 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 227 243 3.4E-41 T 14-10-2018 LH59_20870 800d1986eb0d803bca9305f5baf98659 531 Gene3D G3DSA:3.60.20.40 353 531 3.4E-67 T 14-10-2018 LH59_20870 800d1986eb0d803bca9305f5baf98659 531 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 24 523 1.7E-108 T 14-10-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-4061|MetaCyc: PWY-5826|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7559 LH59_03110 ce444ce97f2029ec8e6ea43db9b9c16a 244 TIGRFAM TIGR02070 mono_pep_trsgly: monofunctional biosynthetic peptidoglycan transglycosylase 22 243 4.7E-88 T 14-10-2018 IPR011812 Biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 LH59_03110 ce444ce97f2029ec8e6ea43db9b9c16a 244 Gene3D G3DSA:1.10.3810.10 65 243 2.3E-55 T 14-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 LH59_03110 ce444ce97f2029ec8e6ea43db9b9c16a 244 Hamap MF_00766 Biosynthetic peptidoglycan transglycosylase [mtgA]. 16 244 39.699 T 14-10-2018 IPR011812 Biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 LH59_03110 ce444ce97f2029ec8e6ea43db9b9c16a 244 Pfam PF00912 Transglycosylase 70 238 1.6E-53 T 14-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 LH59_03110 ce444ce97f2029ec8e6ea43db9b9c16a 244 SUPERFAMILY SSF53955 68 240 5.62E-58 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily LH59_00165 d1f9a62f9af41c7cbbd09ca878993ccf 685 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 3 181 5.8E-61 T 14-10-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 LH59_00165 d1f9a62f9af41c7cbbd09ca878993ccf 685 Gene3D G3DSA:3.30.420.40 1 92 1.8E-7 T 14-10-2018 LH59_00165 d1f9a62f9af41c7cbbd09ca878993ccf 685 Pfam PF01968 Hydantoinase/oxoprolinase 202 488 9.7E-93 T 14-10-2018 IPR002821 Hydantoinase A/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 LH59_00165 d1f9a62f9af41c7cbbd09ca878993ccf 685 SUPERFAMILY SSF53067 1 482 2.95E-13 T 14-10-2018 LH59_00830 029a89cdaa838260be8c3101785e42b8 157 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 8 146 2.7E-29 T 14-10-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like LH59_00830 029a89cdaa838260be8c3101785e42b8 157 Gene3D G3DSA:3.30.1330.40 1 155 2.3E-57 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 LH59_00830 029a89cdaa838260be8c3101785e42b8 157 SUPERFAMILY SSF55298 4 153 9.42E-51 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 LH59_20910 8b7a0be2c05f12d7aeb28bab8bee7940 317 Gene3D G3DSA:1.10.10.10 1 88 1.5E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_20910 8b7a0be2c05f12d7aeb28bab8bee7940 317 Pfam PF03466 LysR substrate binding domain 89 293 8.8E-37 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_20910 8b7a0be2c05f12d7aeb28bab8bee7940 317 SUPERFAMILY SSF46785 1 83 8.71E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_20910 8b7a0be2c05f12d7aeb28bab8bee7940 317 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 6.8E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_20910 8b7a0be2c05f12d7aeb28bab8bee7940 317 Gene3D G3DSA:3.40.190.290 92 301 2.9E-33 T 14-10-2018 LH59_20910 8b7a0be2c05f12d7aeb28bab8bee7940 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 9.5E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_20910 8b7a0be2c05f12d7aeb28bab8bee7940 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 9.5E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_20910 8b7a0be2c05f12d7aeb28bab8bee7940 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 9.5E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_20910 8b7a0be2c05f12d7aeb28bab8bee7940 317 SUPERFAMILY SSF53850 91 296 2.04E-34 T 14-10-2018 LH59_01575 79a8149aa080e3704d1ad318c96929cb 338 PRINTS PR00410 Phenol hydroxylase reductase family signature 145 152 7.9E-20 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 LH59_01575 79a8149aa080e3704d1ad318c96929cb 338 PRINTS PR00410 Phenol hydroxylase reductase family signature 204 223 7.9E-20 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 LH59_01575 79a8149aa080e3704d1ad318c96929cb 338 PRINTS PR00410 Phenol hydroxylase reductase family signature 129 141 7.9E-20 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 LH59_01575 79a8149aa080e3704d1ad318c96929cb 338 PRINTS PR00410 Phenol hydroxylase reductase family signature 294 302 7.9E-20 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 LH59_01575 79a8149aa080e3704d1ad318c96929cb 338 PRINTS PR00410 Phenol hydroxylase reductase family signature 229 238 7.9E-20 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 LH59_01575 79a8149aa080e3704d1ad318c96929cb 338 PRINTS PR00410 Phenol hydroxylase reductase family signature 188 197 7.9E-20 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 LH59_01575 79a8149aa080e3704d1ad318c96929cb 338 SUPERFAMILY SSF63380 99 193 1.86E-22 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel LH59_01575 79a8149aa080e3704d1ad318c96929cb 338 Pfam PF00175 Oxidoreductase NAD-binding domain 205 306 1.4E-24 T 14-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 LH59_01575 79a8149aa080e3704d1ad318c96929cb 338 Gene3D G3DSA:2.40.30.10 99 194 1.1E-21 T 14-10-2018 LH59_01575 79a8149aa080e3704d1ad318c96929cb 338 Pfam PF00970 Oxidoreductase FAD-binding domain 102 195 4.3E-12 T 14-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 LH59_01575 79a8149aa080e3704d1ad318c96929cb 338 SUPERFAMILY SSF52343 197 328 3.54E-39 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain LH59_01575 79a8149aa080e3704d1ad318c96929cb 338 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 129 139 4.1E-12 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 LH59_01575 79a8149aa080e3704d1ad318c96929cb 338 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 204 223 4.1E-12 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 LH59_01575 79a8149aa080e3704d1ad318c96929cb 338 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 229 238 4.1E-12 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 LH59_01575 79a8149aa080e3704d1ad318c96929cb 338 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 241 252 4.1E-12 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 LH59_01575 79a8149aa080e3704d1ad318c96929cb 338 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 145 152 4.1E-12 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 LH59_01575 79a8149aa080e3704d1ad318c96929cb 338 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 294 302 4.1E-12 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 LH59_01575 79a8149aa080e3704d1ad318c96929cb 338 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 37 45 - T 14-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 LH59_01575 79a8149aa080e3704d1ad318c96929cb 338 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 9 80 1.4E-14 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 LH59_01575 79a8149aa080e3704d1ad318c96929cb 338 Gene3D G3DSA:3.10.20.30 1 94 6.9E-26 T 14-10-2018 IPR012675 Beta-grasp domain superfamily LH59_01575 79a8149aa080e3704d1ad318c96929cb 338 Gene3D G3DSA:3.40.50.80 196 329 1.6E-34 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain LH59_01575 79a8149aa080e3704d1ad318c96929cb 338 SUPERFAMILY SSF54292 1 88 3.15E-26 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 LH59_22475 be1e250b787f921f9d254443815e48ce 87 Pfam PF01176 Translation initiation factor 1A / IF-1 8 70 1.5E-21 T 14-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 LH59_22475 be1e250b787f921f9d254443815e48ce 87 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 25.526 T 14-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 LH59_22475 be1e250b787f921f9d254443815e48ce 87 SUPERFAMILY SSF50249 1 71 1.86E-23 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_22475 be1e250b787f921f9d254443815e48ce 87 SMART SM00316 4 72 0.0038 T 14-10-2018 IPR022967 RNA-binding domain, S1 LH59_22475 be1e250b787f921f9d254443815e48ce 87 Gene3D G3DSA:2.40.50.140 1 72 4.3E-30 T 14-10-2018 LH59_22475 be1e250b787f921f9d254443815e48ce 87 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 71 2.5E-29 T 14-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 LH59_06430 aab5b7aa8a20968f30498e1a4d7f8db6 292 Pfam PF01039 Carboxyl transferase domain 101 242 2.4E-15 T 14-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 LH59_06430 aab5b7aa8a20968f30498e1a4d7f8db6 292 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 1 285 2.7E-124 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 LH59_06430 aab5b7aa8a20968f30498e1a4d7f8db6 292 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 1 283 38.099 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 LH59_06430 aab5b7aa8a20968f30498e1a4d7f8db6 292 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 253 262 1.6E-39 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 LH59_06430 aab5b7aa8a20968f30498e1a4d7f8db6 292 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 131 145 1.6E-39 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 LH59_06430 aab5b7aa8a20968f30498e1a4d7f8db6 292 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 202 219 1.6E-39 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 LH59_06430 aab5b7aa8a20968f30498e1a4d7f8db6 292 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 165 183 1.6E-39 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 LH59_06430 aab5b7aa8a20968f30498e1a4d7f8db6 292 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 231 242 1.6E-39 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 LH59_06430 aab5b7aa8a20968f30498e1a4d7f8db6 292 Gene3D G3DSA:3.90.226.10 27 288 3.9E-84 T 14-10-2018 LH59_06430 aab5b7aa8a20968f30498e1a4d7f8db6 292 SUPERFAMILY SSF52096 27 285 4.62E-85 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily LH59_06100 3474a707e0eb497e553ccbe16355fbef 386 Gene3D G3DSA:2.40.160.10 11 386 4.0E-88 T 14-10-2018 IPR023614 Porin domain superfamily LH59_06100 3474a707e0eb497e553ccbe16355fbef 386 PRINTS PR00184 Neisseria sp. porin signature 57 82 1.7E-10 T 14-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 LH59_06100 3474a707e0eb497e553ccbe16355fbef 386 PRINTS PR00184 Neisseria sp. porin signature 157 174 1.7E-10 T 14-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 LH59_06100 3474a707e0eb497e553ccbe16355fbef 386 PRINTS PR00184 Neisseria sp. porin signature 340 364 1.7E-10 T 14-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 LH59_06100 3474a707e0eb497e553ccbe16355fbef 386 Pfam PF13609 Gram-negative porin 7 366 5.7E-57 T 14-10-2018 LH59_06100 3474a707e0eb497e553ccbe16355fbef 386 SUPERFAMILY SSF56935 21 386 3.92E-75 T 14-10-2018 LH59_06100 3474a707e0eb497e553ccbe16355fbef 386 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 55 66 1.1E-6 T 14-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 LH59_06100 3474a707e0eb497e553ccbe16355fbef 386 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 343 360 1.1E-6 T 14-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 LH59_06100 3474a707e0eb497e553ccbe16355fbef 386 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 202 214 1.1E-6 T 14-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 LH59_06100 3474a707e0eb497e553ccbe16355fbef 386 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 99 109 1.1E-6 T 14-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 LH59_06100 3474a707e0eb497e553ccbe16355fbef 386 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 158 169 1.1E-6 T 14-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 LH59_28070 a247e1f80991e97c0cdfcd184fe94118 253 Pfam PF08220 DeoR-like helix-turn-helix domain 6 61 2.0E-14 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 LH59_28070 a247e1f80991e97c0cdfcd184fe94118 253 SUPERFAMILY SSF46785 4 65 1.43E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_28070 a247e1f80991e97c0cdfcd184fe94118 253 SMART SM01134 70 233 1.4E-53 T 14-10-2018 LH59_28070 a247e1f80991e97c0cdfcd184fe94118 253 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 14-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 LH59_28070 a247e1f80991e97c0cdfcd184fe94118 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 5.1E-8 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 LH59_28070 a247e1f80991e97c0cdfcd184fe94118 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 5.1E-8 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 LH59_28070 a247e1f80991e97c0cdfcd184fe94118 253 Pfam PF00455 DeoR C terminal sensor domain 73 231 3.9E-41 T 14-10-2018 IPR014036 DeoR C-terminal sensor domain LH59_28070 a247e1f80991e97c0cdfcd184fe94118 253 Gene3D G3DSA:1.10.10.10 1 57 1.9E-5 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_28070 a247e1f80991e97c0cdfcd184fe94118 253 SMART SM00420 6 58 3.1E-12 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 LH59_28070 a247e1f80991e97c0cdfcd184fe94118 253 SUPERFAMILY SSF100950 72 232 1.59E-27 T 14-10-2018 IPR037171 NagB/RpiA transferase-like LH59_27995 d50136e4dd21551faf0c4b1cad73d016 143 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 141 3.2E-64 T 14-10-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_27995 d50136e4dd21551faf0c4b1cad73d016 143 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 142 31.557 T 14-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 LH59_27995 d50136e4dd21551faf0c4b1cad73d016 143 Pfam PF00298 Ribosomal protein L11, RNA binding domain 72 140 1.5E-24 T 14-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 LH59_27995 d50136e4dd21551faf0c4b1cad73d016 143 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 67 5.7E-29 T 14-10-2018 IPR020784 Ribosomal protein L11, N-terminal LH59_27995 d50136e4dd21551faf0c4b1cad73d016 143 SUPERFAMILY SSF46906 68 141 1.83E-26 T 14-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily LH59_27995 d50136e4dd21551faf0c4b1cad73d016 143 Gene3D G3DSA:3.30.1550.10 2 72 6.3E-35 T 14-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily LH59_27995 d50136e4dd21551faf0c4b1cad73d016 143 SUPERFAMILY SSF54747 3 73 2.22E-30 T 14-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily LH59_27995 d50136e4dd21551faf0c4b1cad73d016 143 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 74 2.0E-16 T 14-10-2018 LH59_27995 d50136e4dd21551faf0c4b1cad73d016 143 SMART SM00649 9 141 4.5E-85 T 14-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 LH59_27995 d50136e4dd21551faf0c4b1cad73d016 143 ProSitePatterns PS00359 Ribosomal protein L11 signature. 127 142 - T 14-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27995 d50136e4dd21551faf0c4b1cad73d016 143 Gene3D G3DSA:1.10.10.250 73 141 8.1E-28 T 14-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily LH59_12515 e1107ef3173ce6468d29a03c01fce2a5 448 ProSitePatterns PS00571 Amidases signature. 153 184 - T 14-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 LH59_12515 e1107ef3173ce6468d29a03c01fce2a5 448 Gene3D G3DSA:3.90.1300.10 4 447 6.8E-124 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_12515 e1107ef3173ce6468d29a03c01fce2a5 448 SUPERFAMILY SSF75304 4 446 1.57E-115 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_12515 e1107ef3173ce6468d29a03c01fce2a5 448 Pfam PF01425 Amidase 21 436 1.6E-83 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_15300 b6f3345cb40dbc7fbec8b5857bdc3451 300 Pfam PF03466 LysR substrate binding domain 96 298 2.0E-21 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_15300 b6f3345cb40dbc7fbec8b5857bdc3451 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 66 1.0E-21 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_15300 b6f3345cb40dbc7fbec8b5857bdc3451 300 Gene3D G3DSA:1.10.10.10 4 90 4.8E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_15300 b6f3345cb40dbc7fbec8b5857bdc3451 300 SUPERFAMILY SSF53850 97 299 2.53E-20 T 14-10-2018 LH59_15300 b6f3345cb40dbc7fbec8b5857bdc3451 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 9.7E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_15300 b6f3345cb40dbc7fbec8b5857bdc3451 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 9.7E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_15300 b6f3345cb40dbc7fbec8b5857bdc3451 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 9.7E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_15300 b6f3345cb40dbc7fbec8b5857bdc3451 300 SUPERFAMILY SSF46785 6 91 6.53E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_15300 b6f3345cb40dbc7fbec8b5857bdc3451 300 Gene3D G3DSA:3.40.190.290 96 285 1.7E-19 T 14-10-2018 LH59_10000 a33f2bb0b43c4865bf521f0f2ec2442d 307 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 99 304 7.2E-8 T 14-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 LH59_10000 a33f2bb0b43c4865bf521f0f2ec2442d 307 PIRSF PIRSF028561 3 307 3.0E-97 T 14-10-2018 IPR014548 Predicted acyltransferase LH59_22440 c87b372fd83ca717be21838236dd37d9 163 Gene3D G3DSA:3.30.450.40 24 153 3.1E-6 T 14-10-2018 IPR029016 GAF-like domain superfamily LH59_22440 c87b372fd83ca717be21838236dd37d9 163 SUPERFAMILY SSF55781 24 144 5.23E-10 T 14-10-2018 LH59_26465 33840c8dcc4732f48fe66daef2a49abb 128 Gene3D G3DSA:1.10.10.10 2 124 1.7E-43 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_26465 33840c8dcc4732f48fe66daef2a49abb 128 SUPERFAMILY SSF46785 10 121 1.32E-33 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_26465 33840c8dcc4732f48fe66daef2a49abb 128 Pfam PF01638 HxlR-like helix-turn-helix 24 111 4.1E-26 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type LH59_13110 6d113891c29cd6f9c5fdd8b4725ef244 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 1.5E-21 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_13110 6d113891c29cd6f9c5fdd8b4725ef244 302 Gene3D G3DSA:3.40.190.10 164 269 1.1E-65 T 14-10-2018 LH59_13110 6d113891c29cd6f9c5fdd8b4725ef244 302 Gene3D G3DSA:1.10.10.10 1 90 5.9E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_13110 6d113891c29cd6f9c5fdd8b4725ef244 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 9.5E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_13110 6d113891c29cd6f9c5fdd8b4725ef244 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 9.5E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_13110 6d113891c29cd6f9c5fdd8b4725ef244 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 9.5E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_13110 6d113891c29cd6f9c5fdd8b4725ef244 302 SUPERFAMILY SSF46785 1 86 5.44E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_13110 6d113891c29cd6f9c5fdd8b4725ef244 302 Gene3D G3DSA:3.40.190.10 91 287 1.1E-65 T 14-10-2018 LH59_13110 6d113891c29cd6f9c5fdd8b4725ef244 302 SUPERFAMILY SSF53850 88 296 8.09E-40 T 14-10-2018 LH59_13110 6d113891c29cd6f9c5fdd8b4725ef244 302 Pfam PF03466 LysR substrate binding domain 87 291 6.0E-46 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_01810 ab5807a74eec83c83b3d45e87e17afa9 630 Pfam PF01590 GAF domain 73 202 2.9E-9 T 14-10-2018 IPR003018 GAF domain GO:0005515 LH59_01810 ab5807a74eec83c83b3d45e87e17afa9 630 Gene3D G3DSA:1.10.10.60 578 623 4.3E-14 T 14-10-2018 LH59_01810 ab5807a74eec83c83b3d45e87e17afa9 630 Pfam PF02954 Bacterial regulatory protein, Fis family 591 620 2.0E-10 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 LH59_01810 ab5807a74eec83c83b3d45e87e17afa9 630 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 590 607 3.3E-7 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 LH59_01810 ab5807a74eec83c83b3d45e87e17afa9 630 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 607 627 3.3E-7 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 LH59_01810 ab5807a74eec83c83b3d45e87e17afa9 630 Gene3D G3DSA:1.10.8.60 505 572 2.0E-5 T 14-10-2018 LH59_01810 ab5807a74eec83c83b3d45e87e17afa9 630 SUPERFAMILY SSF55781 122 203 9.16E-7 T 14-10-2018 LH59_01810 ab5807a74eec83c83b3d45e87e17afa9 630 Pfam PF00158 Sigma-54 interaction domain 341 495 2.4E-57 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 LH59_01810 ab5807a74eec83c83b3d45e87e17afa9 630 Gene3D G3DSA:3.30.450.40 22 206 4.2E-51 T 14-10-2018 IPR029016 GAF-like domain superfamily LH59_01810 ab5807a74eec83c83b3d45e87e17afa9 630 SUPERFAMILY SSF46689 574 626 2.91E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_01810 ab5807a74eec83c83b3d45e87e17afa9 630 SMART SM00382 348 492 3.5E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_01810 ab5807a74eec83c83b3d45e87e17afa9 630 SUPERFAMILY SSF52540 345 564 5.2E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_01810 ab5807a74eec83c83b3d45e87e17afa9 630 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 352 365 - T 14-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 LH59_01810 ab5807a74eec83c83b3d45e87e17afa9 630 Gene3D G3DSA:3.40.50.300 329 500 2.2E-52 T 14-10-2018 LH59_05850 6acc406caca300e1a2849fc209fcc026 814 Pfam PF07660 Secretin and TonB N terminus short domain 69 117 5.7E-7 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 LH59_05850 6acc406caca300e1a2849fc209fcc026 814 Pfam PF07715 TonB-dependent Receptor Plug Domain 158 257 7.2E-16 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_05850 6acc406caca300e1a2849fc209fcc026 814 SUPERFAMILY SSF56935 119 814 2.29E-120 T 14-10-2018 LH59_05850 6acc406caca300e1a2849fc209fcc026 814 SMART SM00965 67 118 8.2E-11 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 LH59_05850 6acc406caca300e1a2849fc209fcc026 814 Gene3D G3DSA:2.170.130.10 136 266 6.6E-37 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily LH59_05850 6acc406caca300e1a2849fc209fcc026 814 Gene3D G3DSA:2.40.170.20 267 814 5.1E-159 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_05850 6acc406caca300e1a2849fc209fcc026 814 Gene3D G3DSA:3.55.50.30 45 116 8.7E-26 T 14-10-2018 LH59_05850 6acc406caca300e1a2849fc209fcc026 814 Pfam PF00593 TonB dependent receptor 363 813 2.0E-50 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_05850 6acc406caca300e1a2849fc209fcc026 814 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 160 813 6.2E-109 T 14-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 LH59_09505 72d7738e8b1e2f2e25e4c6fee55262ca 593 Gene3D G3DSA:3.50.30.80 381 544 1.1E-33 T 14-10-2018 LH59_09505 72d7738e8b1e2f2e25e4c6fee55262ca 593 Pfam PF00920 Dehydratase family 44 570 5.0E-153 T 14-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 LH59_09505 72d7738e8b1e2f2e25e4c6fee55262ca 593 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 127 137 - T 14-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 LH59_09505 72d7738e8b1e2f2e25e4c6fee55262ca 593 SUPERFAMILY SSF52016 381 577 6.83E-46 T 14-10-2018 LH59_09505 72d7738e8b1e2f2e25e4c6fee55262ca 593 SUPERFAMILY SSF143975 6 378 7.06E-115 T 14-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 LH59_03645 239f97743c8ac985c2c193d1a90b26d1 350 SUPERFAMILY SSF53448 38 270 1.07E-38 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases LH59_03645 239f97743c8ac985c2c193d1a90b26d1 350 Gene3D G3DSA:3.90.550.10 26 224 2.4E-34 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases LH59_03645 239f97743c8ac985c2c193d1a90b26d1 350 Pfam PF00535 Glycosyl transferase family 2 40 199 1.5E-31 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 LH59_10495 44221355b3270f97687a2f7e014d87e4 151 SUPERFAMILY SSF82093 29 134 2.09E-38 T 14-10-2018 IPR036127 CcmE-like superfamily GO:0005886|GO:0017003|GO:0017004 LH59_10495 44221355b3270f97687a2f7e014d87e4 151 Hamap MF_01959 Cytochrome c-type biogenesis protein CcmE [ccmE]. 1 138 33.13 T 14-10-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004|GO:0020037 LH59_10495 44221355b3270f97687a2f7e014d87e4 151 Pfam PF03100 CcmE 4 128 1.4E-46 T 14-10-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004|GO:0020037 LH59_10495 44221355b3270f97687a2f7e014d87e4 151 Gene3D G3DSA:2.40.50.140 29 134 1.1E-38 T 14-10-2018 LH59_21780 292206539419d6ad8e9ee90de41ab972 252 Pfam PF06912 Protein of unknown function (DUF1275) 22 238 1.7E-35 T 14-10-2018 IPR010699 Protein of unknown function DUF1275 LH59_27495 abb1da74d1bca03362388d7b2f384230 595 Gene3D G3DSA:2.40.50.140 1 104 6.5E-32 T 14-10-2018 LH59_27495 abb1da74d1bca03362388d7b2f384230 595 Gene3D G3DSA:3.30.1360.30 272 426 5.7E-195 T 14-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 LH59_27495 abb1da74d1bca03362388d7b2f384230 595 PRINTS PR01042 Aspartyl-tRNA synthetase signature 190 202 1.4E-26 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 LH59_27495 abb1da74d1bca03362388d7b2f384230 595 PRINTS PR01042 Aspartyl-tRNA synthetase signature 480 496 1.4E-26 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 LH59_27495 abb1da74d1bca03362388d7b2f384230 595 PRINTS PR01042 Aspartyl-tRNA synthetase signature 524 538 1.4E-26 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 LH59_27495 abb1da74d1bca03362388d7b2f384230 595 PRINTS PR01042 Aspartyl-tRNA synthetase signature 207 220 1.4E-26 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 LH59_27495 abb1da74d1bca03362388d7b2f384230 595 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 1 590 33.532 T 14-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 LH59_27495 abb1da74d1bca03362388d7b2f384230 595 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 1 588 1.2E-241 T 14-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 LH59_27495 abb1da74d1bca03362388d7b2f384230 595 Pfam PF02938 GAD domain 309 406 1.4E-27 T 14-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 LH59_27495 abb1da74d1bca03362388d7b2f384230 595 SUPERFAMILY SSF55261 291 416 1.8E-41 T 14-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 LH59_27495 abb1da74d1bca03362388d7b2f384230 595 Pfam PF01336 OB-fold nucleic acid binding domain 18 101 3.7E-17 T 14-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 LH59_27495 abb1da74d1bca03362388d7b2f384230 595 Pfam PF00152 tRNA synthetases class II (D, K and N) 118 564 8.2E-107 T 14-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 LH59_27495 abb1da74d1bca03362388d7b2f384230 595 Gene3D G3DSA:3.30.930.10 117 588 5.7E-195 T 14-10-2018 LH59_27495 abb1da74d1bca03362388d7b2f384230 595 SUPERFAMILY SSF55681 110 591 9.22E-103 T 14-10-2018 LH59_27495 abb1da74d1bca03362388d7b2f384230 595 SUPERFAMILY SSF50249 1 104 2.48E-31 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_12890 a4254a7729ce3cfd290b9689bea6b604 430 Pfam PF00512 His Kinase A (phospho-acceptor) domain 211 274 4.3E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_12890 a4254a7729ce3cfd290b9689bea6b604 430 SUPERFAMILY SSF55874 265 427 9.95E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_12890 a4254a7729ce3cfd290b9689bea6b604 430 SUPERFAMILY SSF47384 196 274 3.92E-12 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 LH59_12890 a4254a7729ce3cfd290b9689bea6b604 430 SMART SM00388 210 275 2.7E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_12890 a4254a7729ce3cfd290b9689bea6b604 430 SMART SM00387 320 430 1.5E-26 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_12890 a4254a7729ce3cfd290b9689bea6b604 430 Gene3D G3DSA:3.30.565.10 282 429 4.2E-32 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_12890 a4254a7729ce3cfd290b9689bea6b604 430 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 325 427 1.3E-18 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_12890 a4254a7729ce3cfd290b9689bea6b604 430 Gene3D G3DSA:1.10.287.130 161 276 5.2E-22 T 14-10-2018 LH59_12890 a4254a7729ce3cfd290b9689bea6b604 430 SMART SM00304 157 209 0.0099 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_12890 a4254a7729ce3cfd290b9689bea6b604 430 PRINTS PR00344 Bacterial sensor protein C-terminal signature 391 409 4.8E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_12890 a4254a7729ce3cfd290b9689bea6b604 430 PRINTS PR00344 Bacterial sensor protein C-terminal signature 356 370 4.8E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_12890 a4254a7729ce3cfd290b9689bea6b604 430 PRINTS PR00344 Bacterial sensor protein C-terminal signature 374 384 4.8E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_05790 2c213ae708bd829a9a0725a587a3a752 261 Pfam PF13531 Bacterial extracellular solute-binding protein 33 258 1.1E-33 T 14-10-2018 LH59_05790 2c213ae708bd829a9a0725a587a3a752 261 Gene3D G3DSA:3.40.190.10 34 258 2.9E-85 T 14-10-2018 LH59_05790 2c213ae708bd829a9a0725a587a3a752 261 Gene3D G3DSA:3.40.190.10 112 222 2.9E-85 T 14-10-2018 LH59_05790 2c213ae708bd829a9a0725a587a3a752 261 SUPERFAMILY SSF53850 29 258 2.58E-36 T 14-10-2018 LH59_03525 4d1f26afe873db702509fca3e7457736 369 PRINTS PR00992 Alanine racemase signature 31 47 2.9E-43 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LH59_03525 4d1f26afe873db702509fca3e7457736 369 PRINTS PR00992 Alanine racemase signature 256 271 2.9E-43 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LH59_03525 4d1f26afe873db702509fca3e7457736 369 PRINTS PR00992 Alanine racemase signature 162 173 2.9E-43 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LH59_03525 4d1f26afe873db702509fca3e7457736 369 PRINTS PR00992 Alanine racemase signature 199 226 2.9E-43 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LH59_03525 4d1f26afe873db702509fca3e7457736 369 PRINTS PR00992 Alanine racemase signature 294 311 2.9E-43 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LH59_03525 4d1f26afe873db702509fca3e7457736 369 PRINTS PR00992 Alanine racemase signature 347 360 2.9E-43 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LH59_03525 4d1f26afe873db702509fca3e7457736 369 PRINTS PR00992 Alanine racemase signature 65 83 2.9E-43 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LH59_03525 4d1f26afe873db702509fca3e7457736 369 PRINTS PR00992 Alanine racemase signature 273 288 2.9E-43 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LH59_03525 4d1f26afe873db702509fca3e7457736 369 Pfam PF01168 Alanine racemase, N-terminal domain 10 226 4.8E-45 T 14-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LH59_03525 4d1f26afe873db702509fca3e7457736 369 Hamap MF_01201 Alanine racemase. 3 365 28.16 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LH59_03525 4d1f26afe873db702509fca3e7457736 369 SUPERFAMILY SSF51419 10 241 1.87E-44 T 14-10-2018 IPR029066 PLP-binding barrel LH59_03525 4d1f26afe873db702509fca3e7457736 369 Pfam PF00842 Alanine racemase, C-terminal domain 240 361 8.7E-37 T 14-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LH59_03525 4d1f26afe873db702509fca3e7457736 369 TIGRFAM TIGR00492 alr: alanine racemase 6 363 3.5E-81 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LH59_03525 4d1f26afe873db702509fca3e7457736 369 SMART SM01005 240 365 2.0E-53 T 14-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LH59_03525 4d1f26afe873db702509fca3e7457736 369 Gene3D G3DSA:3.20.20.10 12 224 1.9E-91 T 14-10-2018 IPR029066 PLP-binding barrel LH59_03525 4d1f26afe873db702509fca3e7457736 369 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 36 46 - T 14-10-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LH59_03525 4d1f26afe873db702509fca3e7457736 369 Gene3D G3DSA:2.40.37.10 225 360 1.9E-91 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 LH59_03525 4d1f26afe873db702509fca3e7457736 369 SUPERFAMILY SSF50621 235 362 1.81E-39 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 LH59_14900 3b63ede8b999f8e65aa32181c1ce5b1b 603 Gene3D G3DSA:3.40.50.1220 186 371 1.3E-48 T 14-10-2018 LH59_14900 3b63ede8b999f8e65aa32181c1ce5b1b 603 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 7 172 1.4E-48 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 LH59_14900 3b63ede8b999f8e65aa32181c1ce5b1b 603 TIGRFAM TIGR03457 sulphoacet_xsc: sulfoacetaldehyde acetyltransferase 6 581 9.0E-283 T 14-10-2018 IPR017820 Sulphoacetaldehyde acetyltransferase GO:0000287|GO:0005737|GO:0019529|GO:0030976|GO:0050487 KEGG: 00430+2.3.3.15|MetaCyc: PWY-1281|MetaCyc: PWY-6637 LH59_14900 3b63ede8b999f8e65aa32181c1ce5b1b 603 SUPERFAMILY SSF52518 3 182 2.95E-49 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold LH59_14900 3b63ede8b999f8e65aa32181c1ce5b1b 603 Gene3D G3DSA:3.40.50.970 1 178 1.5E-55 T 14-10-2018 LH59_14900 3b63ede8b999f8e65aa32181c1ce5b1b 603 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 192 329 3.4E-32 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 LH59_14900 3b63ede8b999f8e65aa32181c1ce5b1b 603 SUPERFAMILY SSF52518 383 583 3.04E-52 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold LH59_14900 3b63ede8b999f8e65aa32181c1ce5b1b 603 Gene3D G3DSA:3.40.50.970 379 568 5.5E-54 T 14-10-2018 LH59_14900 3b63ede8b999f8e65aa32181c1ce5b1b 603 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 406 554 1.2E-36 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 LH59_14900 3b63ede8b999f8e65aa32181c1ce5b1b 603 SUPERFAMILY SSF52467 182 365 5.64E-42 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily LH59_17170 3710b4507d9b730b910e160793fe75fe 620 Hamap MF_00679 Chaperone protein HscA [hscA]. 1 619 42.85 T 14-10-2018 IPR010236 ISC system FeS cluster assembly, HscA chaperone GO:0005524|GO:0006457|GO:0016226|GO:0016887|GO:0051082 LH59_17170 3710b4507d9b730b910e160793fe75fe 620 SUPERFAMILY SSF100934 507 618 4.51E-32 T 14-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 LH59_17170 3710b4507d9b730b910e160793fe75fe 620 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 24 31 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 LH59_17170 3710b4507d9b730b910e160793fe75fe 620 Gene3D G3DSA:3.30.420.40 192 363 2.2E-111 T 14-10-2018 LH59_17170 3710b4507d9b730b910e160793fe75fe 620 TIGRFAM TIGR01991 HscA: Fe-S protein assembly chaperone HscA 21 618 5.7E-276 T 14-10-2018 IPR010236 ISC system FeS cluster assembly, HscA chaperone GO:0005524|GO:0006457|GO:0016226|GO:0016887|GO:0051082 LH59_17170 3710b4507d9b730b910e160793fe75fe 620 Gene3D G3DSA:1.20.1270.10 524 618 2.0E-26 T 14-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 LH59_17170 3710b4507d9b730b910e160793fe75fe 620 SUPERFAMILY SSF53067 19 194 2.43E-50 T 14-10-2018 LH59_17170 3710b4507d9b730b910e160793fe75fe 620 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 334 348 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 LH59_17170 3710b4507d9b730b910e160793fe75fe 620 Gene3D G3DSA:3.90.640.10 236 313 2.2E-111 T 14-10-2018 LH59_17170 3710b4507d9b730b910e160793fe75fe 620 SUPERFAMILY SSF53067 198 378 2.11E-50 T 14-10-2018 LH59_17170 3710b4507d9b730b910e160793fe75fe 620 Gene3D G3DSA:2.60.34.10 382 523 2.6E-48 T 14-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 LH59_17170 3710b4507d9b730b910e160793fe75fe 620 Pfam PF00012 Hsp70 protein 21 602 9.5E-179 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LH59_17170 3710b4507d9b730b910e160793fe75fe 620 SUPERFAMILY SSF100920 387 537 3.14E-48 T 14-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 LH59_17170 3710b4507d9b730b910e160793fe75fe 620 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 203 216 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 LH59_17170 3710b4507d9b730b910e160793fe75fe 620 PRINTS PR00301 70kDa heat shock protein signature 388 407 2.6E-54 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LH59_17170 3710b4507d9b730b910e160793fe75fe 620 PRINTS PR00301 70kDa heat shock protein signature 331 347 2.6E-54 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LH59_17170 3710b4507d9b730b910e160793fe75fe 620 PRINTS PR00301 70kDa heat shock protein signature 150 170 2.6E-54 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LH59_17170 3710b4507d9b730b910e160793fe75fe 620 PRINTS PR00301 70kDa heat shock protein signature 209 219 2.6E-54 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LH59_17170 3710b4507d9b730b910e160793fe75fe 620 PRINTS PR00301 70kDa heat shock protein signature 48 60 2.6E-54 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LH59_17170 3710b4507d9b730b910e160793fe75fe 620 PRINTS PR00301 70kDa heat shock protein signature 469 485 2.6E-54 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LH59_17170 3710b4507d9b730b910e160793fe75fe 620 PRINTS PR00301 70kDa heat shock protein signature 362 382 2.6E-54 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LH59_17170 3710b4507d9b730b910e160793fe75fe 620 PRINTS PR00301 70kDa heat shock protein signature 20 33 2.6E-54 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LH59_17170 3710b4507d9b730b910e160793fe75fe 620 Gene3D G3DSA:3.30.420.40 22 376 2.2E-111 T 14-10-2018 LH59_12620 7413454bf6ecde50666cafa53e62cfff 206 Gene3D G3DSA:3.40.50.850 4 197 2.5E-58 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 LH59_12620 7413454bf6ecde50666cafa53e62cfff 206 Pfam PF00857 Isochorismatase family 23 195 1.0E-43 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 LH59_12620 7413454bf6ecde50666cafa53e62cfff 206 SUPERFAMILY SSF52499 3 199 9.42E-58 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 LH59_07900 627caa1f0e1c239163a1206311176b45 398 SUPERFAMILY SSF160996 185 336 6.41E-11 T 14-10-2018 LH59_07900 627caa1f0e1c239163a1206311176b45 398 Pfam PF03486 HI0933-like protein 1 389 7.0E-95 T 14-10-2018 LH59_07900 627caa1f0e1c239163a1206311176b45 398 TIGRFAM TIGR03862 flavo_PP4765: flavoprotein, TIGR03862 family 10 395 5.2E-158 T 14-10-2018 IPR022460 Conserved hyptotheical protein CHP03862, flavoprotein, PP4765 LH59_07900 627caa1f0e1c239163a1206311176b45 398 Gene3D G3DSA:2.40.30.10 181 337 5.6E-57 T 14-10-2018 LH59_07900 627caa1f0e1c239163a1206311176b45 398 Gene3D G3DSA:3.50.50.60 6 388 5.6E-57 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_07900 627caa1f0e1c239163a1206311176b45 398 Gene3D G3DSA:1.10.8.260 265 320 5.6E-57 T 14-10-2018 IPR023166 HI0933-like insert domain superfamily LH59_07900 627caa1f0e1c239163a1206311176b45 398 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 1 388 1.6E-70 T 14-10-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like LH59_07900 627caa1f0e1c239163a1206311176b45 398 SUPERFAMILY SSF51905 1 394 3.33E-33 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_16250 844865bacf15458e81fbcc99236ca241 191 Gene3D G3DSA:1.20.1290.10 73 190 1.1E-34 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 LH59_16250 844865bacf15458e81fbcc99236ca241 191 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 71 100 6.8E-10 T 14-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 LH59_16250 844865bacf15458e81fbcc99236ca241 191 Pfam PF02627 Carboxymuconolactone decarboxylase family 53 130 4.5E-14 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 LH59_16250 844865bacf15458e81fbcc99236ca241 191 SUPERFAMILY SSF69118 9 186 4.87E-43 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 LH59_16250 844865bacf15458e81fbcc99236ca241 191 TIGRFAM TIGR01926 peroxid_rel: uncharacterized peroxidase-related enzyme 15 187 8.5E-65 T 14-10-2018 IPR010195 Uncharacterised peroxidase-related LH59_11825 5fd10d691f586a56936fc152db5a4812 256 Gene3D G3DSA:3.20.20.140 1 255 3.9E-90 T 14-10-2018 LH59_11825 5fd10d691f586a56936fc152db5a4812 256 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 188 204 - T 14-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 LH59_11825 5fd10d691f586a56936fc152db5a4812 256 SUPERFAMILY SSF51556 1 252 5.58E-88 T 14-10-2018 IPR032466 Metal-dependent hydrolase LH59_11825 5fd10d691f586a56936fc152db5a4812 256 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 2 252 4.3E-83 T 14-10-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 LH59_11825 5fd10d691f586a56936fc152db5a4812 256 PIRSF PIRSF005902 1 255 5.3E-79 T 14-10-2018 IPR001130 TatD family GO:0016788 LH59_11825 5fd10d691f586a56936fc152db5a4812 256 Pfam PF01026 TatD related DNase 3 252 7.7E-78 T 14-10-2018 IPR001130 TatD family GO:0016788 LH59_11825 5fd10d691f586a56936fc152db5a4812 256 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 14-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 LH59_06105 61619dd8dfe7689f7b1b4ef7d93ee7f5 119 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 22 118 1.9E-39 T 14-10-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06105 61619dd8dfe7689f7b1b4ef7d93ee7f5 119 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 2 119 20.287 T 14-10-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 LH59_06105 61619dd8dfe7689f7b1b4ef7d93ee7f5 119 Gene3D G3DSA:1.20.58.1610 1 119 5.8E-45 T 14-10-2018 IPR038430 NADH:ubiquinone oxidoreductase, subunit 3 superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_01430 19578a8febb20df6ceff90e05c115821 369 TIGRFAM TIGR02818 adh_III_F_hyde: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 2 369 1.6E-221 T 14-10-2018 IPR014183 Alcohol dehydrogenase class III GO:0006069|GO:0008270|GO:0051903|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00680+1.1.1.284|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-1801|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396|MetaCyc: PWY-7798|Reactome: R-HSA-71384 LH59_01430 19578a8febb20df6ceff90e05c115821 369 SMART SM00829 10 367 0.0013 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 LH59_01430 19578a8febb20df6ceff90e05c115821 369 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 LH59_01430 19578a8febb20df6ceff90e05c115821 369 Gene3D G3DSA:3.40.50.720 174 312 1.3E-151 T 14-10-2018 LH59_01430 19578a8febb20df6ceff90e05c115821 369 SUPERFAMILY SSF50129 318 369 3.63E-12 T 14-10-2018 IPR011032 GroES-like superfamily LH59_01430 19578a8febb20df6ceff90e05c115821 369 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 154 1.8E-25 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 LH59_01430 19578a8febb20df6ceff90e05c115821 369 SUPERFAMILY SSF50129 1 186 2.43E-73 T 14-10-2018 IPR011032 GroES-like superfamily LH59_01430 19578a8febb20df6ceff90e05c115821 369 Gene3D G3DSA:3.90.180.10 6 364 1.3E-151 T 14-10-2018 LH59_01430 19578a8febb20df6ceff90e05c115821 369 Pfam PF00107 Zinc-binding dehydrogenase 197 330 1.0E-22 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 LH59_01430 19578a8febb20df6ceff90e05c115821 369 SUPERFAMILY SSF51735 160 334 3.73E-46 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_05610 5ee132aac982b29027befcd941112e73 209 SUPERFAMILY SSF46689 10 71 5.99E-8 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_05610 5ee132aac982b29027befcd941112e73 209 Gene3D G3DSA:1.10.357.10 2 207 2.5E-19 T 14-10-2018 LH59_20045 c11bc3a233c01177799c7fe6f5ada578 782 SUPERFAMILY SSF47203 321 468 1.01E-24 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 LH59_20045 c11bc3a233c01177799c7fe6f5ada578 782 Gene3D G3DSA:1.20.140.10 321 468 9.4E-99 T 14-10-2018 LH59_20045 c11bc3a233c01177799c7fe6f5ada578 782 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 321 468 3.1E-13 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LH59_20045 c11bc3a233c01177799c7fe6f5ada578 782 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 93 194 3.6E-20 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 LH59_20045 c11bc3a233c01177799c7fe6f5ada578 782 Gene3D G3DSA:1.10.540.10 83 196 9.4E-99 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 LH59_20045 c11bc3a233c01177799c7fe6f5ada578 782 Pfam PF09317 Domain of unknown function (DUF1974) 475 763 7.8E-116 T 14-10-2018 IPR015396 Acyl-CoA dehydrogenase, C-termina, bacterial type GO:0003995|GO:0033539|GO:0055114 KEGG: 00071+1.3.8.8+1.3.8.7|KEGG: 00280+1.3.8.7|KEGG: 00410+1.3.8.7|KEGG: 00640+1.3.8.7|MetaCyc: PWY-7094|MetaCyc: PWY-7654 LH59_20045 c11bc3a233c01177799c7fe6f5ada578 782 Gene3D G3DSA:2.40.110.10 197 320 9.4E-99 T 14-10-2018 LH59_20045 c11bc3a233c01177799c7fe6f5ada578 782 SUPERFAMILY SSF56645 81 315 4.19E-46 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 LH59_03170 8229fd91e08f1e849a008f5d8be9d2f5 144 Gene3D G3DSA:3.40.50.9100 1 144 2.0E-63 T 14-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 LH59_03170 8229fd91e08f1e849a008f5d8be9d2f5 144 PIRSF PIRSF001399 1 144 8.9E-57 T 14-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 LH59_03170 8229fd91e08f1e849a008f5d8be9d2f5 144 ProSitePatterns PS01029 Dehydroquinase class II signature. 8 25 - T 14-10-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 LH59_03170 8229fd91e08f1e849a008f5d8be9d2f5 144 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 144 70.746 T 14-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 LH59_03170 8229fd91e08f1e849a008f5d8be9d2f5 144 Pfam PF01220 Dehydroquinase class II 4 141 4.9E-59 T 14-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 LH59_03170 8229fd91e08f1e849a008f5d8be9d2f5 144 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 5 141 3.0E-63 T 14-10-2018 LH59_03170 8229fd91e08f1e849a008f5d8be9d2f5 144 SUPERFAMILY SSF52304 4 143 6.28E-60 T 14-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 LH59_03170 8229fd91e08f1e849a008f5d8be9d2f5 144 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 5 143 1.3E-57 T 14-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 LH59_17880 5d8eacd0a3530f9cdf494b32e2a2dd94 769 Gene3D G3DSA:1.10.8.60 360 442 8.7E-33 T 14-10-2018 LH59_17880 5d8eacd0a3530f9cdf494b32e2a2dd94 769 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 522 540 - T 14-10-2018 IPR028299 ClpA/B, conserved site 2 LH59_17880 5d8eacd0a3530f9cdf494b32e2a2dd94 769 TIGRFAM TIGR02639 ClpA: ATP-dependent Clp protease ATP-binding subunit ClpA 3 738 0.0 T 14-10-2018 IPR013461 ATP-dependent Clp protease ATP-binding subunit ClpA GO:0016887|GO:0043335 LH59_17880 5d8eacd0a3530f9cdf494b32e2a2dd94 769 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 13 61 1.8E-12 T 14-10-2018 IPR004176 Clp, N-terminal LH59_17880 5d8eacd0a3530f9cdf494b32e2a2dd94 769 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 306 318 - T 14-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 LH59_17880 5d8eacd0a3530f9cdf494b32e2a2dd94 769 Gene3D G3DSA:1.10.8.60 657 759 1.3E-26 T 14-10-2018 LH59_17880 5d8eacd0a3530f9cdf494b32e2a2dd94 769 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 215 345 4.4E-12 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 LH59_17880 5d8eacd0a3530f9cdf494b32e2a2dd94 769 SUPERFAMILY SSF81923 2 143 1.57E-54 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 LH59_17880 5d8eacd0a3530f9cdf494b32e2a2dd94 769 SUPERFAMILY SSF52540 441 742 1.14E-77 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_17880 5d8eacd0a3530f9cdf494b32e2a2dd94 769 SMART SM00382 491 640 4.7E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_17880 5d8eacd0a3530f9cdf494b32e2a2dd94 769 SMART SM00382 210 355 1.2E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_17880 5d8eacd0a3530f9cdf494b32e2a2dd94 769 Gene3D G3DSA:3.40.50.300 443 655 7.7E-78 T 14-10-2018 LH59_17880 5d8eacd0a3530f9cdf494b32e2a2dd94 769 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 566 584 2.8E-38 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 LH59_17880 5d8eacd0a3530f9cdf494b32e2a2dd94 769 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 495 513 2.8E-38 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 LH59_17880 5d8eacd0a3530f9cdf494b32e2a2dd94 769 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 599 613 2.8E-38 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 LH59_17880 5d8eacd0a3530f9cdf494b32e2a2dd94 769 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 537 555 2.8E-38 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 LH59_17880 5d8eacd0a3530f9cdf494b32e2a2dd94 769 SUPERFAMILY SSF52540 172 419 1.09E-69 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_17880 5d8eacd0a3530f9cdf494b32e2a2dd94 769 Pfam PF07724 AAA domain (Cdc48 subfamily) 490 651 8.9E-46 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 LH59_17880 5d8eacd0a3530f9cdf494b32e2a2dd94 769 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 657 737 1.6E-21 T 14-10-2018 IPR019489 Clp ATPase, C-terminal LH59_17880 5d8eacd0a3530f9cdf494b32e2a2dd94 769 Gene3D G3DSA:3.40.50.300 170 359 6.1E-67 T 14-10-2018 LH59_17880 5d8eacd0a3530f9cdf494b32e2a2dd94 769 Gene3D G3DSA:1.10.1780.10 1 144 8.8E-39 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 LH59_17880 5d8eacd0a3530f9cdf494b32e2a2dd94 769 SMART SM01086 657 747 1.2E-31 T 14-10-2018 IPR019489 Clp ATPase, C-terminal LH59_09170 2c09b5edb146a4e13a67c93b76e93b75 431 Pfam PF13393 Histidyl-tRNA synthetase 16 318 1.3E-46 T 14-10-2018 LH59_09170 2c09b5edb146a4e13a67c93b76e93b75 431 Pfam PF03129 Anticodon binding domain 336 427 6.8E-10 T 14-10-2018 IPR004154 Anticodon-binding LH59_09170 2c09b5edb146a4e13a67c93b76e93b75 431 SUPERFAMILY SSF55681 13 322 1.9E-99 T 14-10-2018 LH59_09170 2c09b5edb146a4e13a67c93b76e93b75 431 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 9 431 31.945 T 14-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 LH59_09170 2c09b5edb146a4e13a67c93b76e93b75 431 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 13 410 6.8E-151 T 14-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 LH59_09170 2c09b5edb146a4e13a67c93b76e93b75 431 Gene3D G3DSA:3.30.930.10 8 329 9.9E-118 T 14-10-2018 LH59_09170 2c09b5edb146a4e13a67c93b76e93b75 431 SUPERFAMILY SSF52954 332 427 1.49E-19 T 14-10-2018 LH59_09170 2c09b5edb146a4e13a67c93b76e93b75 431 Gene3D G3DSA:3.40.50.800 332 430 5.0E-22 T 14-10-2018 IPR036621 Anticodon-binding domain superfamily LH59_09170 2c09b5edb146a4e13a67c93b76e93b75 431 PIRSF PIRSF001549 7 429 4.3E-113 T 14-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 LH59_17760 09c7bd8e6a04d3c911b4bdbc7b056de4 370 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 339 8.2E-67 T 14-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 LH59_17760 09c7bd8e6a04d3c911b4bdbc7b056de4 370 Gene3D G3DSA:3.20.20.70 1 354 1.0E-120 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_17760 09c7bd8e6a04d3c911b4bdbc7b056de4 370 SUPERFAMILY SSF51395 1 353 8.74E-115 T 14-10-2018 LH59_11030 1b7c73db06952c43f245f46d59e98d64 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 14-10-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 LH59_11030 1b7c73db06952c43f245f46d59e98d64 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 14-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 LH59_11030 1b7c73db06952c43f245f46d59e98d64 112 SMART SM00938 4 105 3.7E-68 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 LH59_11030 1b7c73db06952c43f245f46d59e98d64 112 PRINTS PR00340 P-II protein signature 23 41 4.4E-45 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 LH59_11030 1b7c73db06952c43f245f46d59e98d64 112 PRINTS PR00340 P-II protein signature 52 75 4.4E-45 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 LH59_11030 1b7c73db06952c43f245f46d59e98d64 112 PRINTS PR00340 P-II protein signature 2 17 4.4E-45 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 LH59_11030 1b7c73db06952c43f245f46d59e98d64 112 PRINTS PR00340 P-II protein signature 83 103 4.4E-45 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 LH59_11030 1b7c73db06952c43f245f46d59e98d64 112 SUPERFAMILY SSF54913 2 112 3.81E-45 T 14-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta LH59_11030 1b7c73db06952c43f245f46d59e98d64 112 Gene3D G3DSA:3.30.70.120 1 112 4.0E-48 T 14-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal LH59_11030 1b7c73db06952c43f245f46d59e98d64 112 PIRSF PIRSF039144 1 112 9.8E-55 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 LH59_11030 1b7c73db06952c43f245f46d59e98d64 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 4.8E-44 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 LH59_21215 407247666a64113c42e36b497030f2ce 1073 Pfam PF00873 AcrB/AcrD/AcrF family 1 1025 0.0 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_21215 407247666a64113c42e36b497030f2ce 1073 SUPERFAMILY SSF82693 38 128 2.09E-25 T 14-10-2018 LH59_21215 407247666a64113c42e36b497030f2ce 1073 Gene3D G3DSA:3.30.2090.10 179 275 0.0 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_21215 407247666a64113c42e36b497030f2ce 1073 SUPERFAMILY SSF82693 672 856 1.41E-25 T 14-10-2018 LH59_21215 407247666a64113c42e36b497030f2ce 1073 Gene3D G3DSA:3.30.70.1430 38 817 0.0 T 14-10-2018 LH59_21215 407247666a64113c42e36b497030f2ce 1073 SUPERFAMILY SSF82693 566 669 2.44E-26 T 14-10-2018 LH59_21215 407247666a64113c42e36b497030f2ce 1073 Gene3D G3DSA:1.20.1640.10 514 1022 0.0 T 14-10-2018 LH59_21215 407247666a64113c42e36b497030f2ce 1073 Gene3D G3DSA:3.30.70.1430 568 668 0.0 T 14-10-2018 LH59_21215 407247666a64113c42e36b497030f2ce 1073 SUPERFAMILY SSF82693 135 329 8.37E-24 T 14-10-2018 LH59_21215 407247666a64113c42e36b497030f2ce 1073 SUPERFAMILY SSF82866 831 1024 3.53E-44 T 14-10-2018 LH59_21215 407247666a64113c42e36b497030f2ce 1073 Gene3D G3DSA:3.30.70.1320 133 332 0.0 T 14-10-2018 LH59_21215 407247666a64113c42e36b497030f2ce 1073 Gene3D G3DSA:1.20.1640.10 8 513 0.0 T 14-10-2018 LH59_21215 407247666a64113c42e36b497030f2ce 1073 Gene3D G3DSA:3.30.2090.10 721 809 0.0 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_21215 407247666a64113c42e36b497030f2ce 1073 SUPERFAMILY SSF82714 182 272 5.62E-21 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_21215 407247666a64113c42e36b497030f2ce 1073 SUPERFAMILY SSF82714 723 808 1.07E-16 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_21215 407247666a64113c42e36b497030f2ce 1073 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 1 1033 0.0 T 14-10-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0006855|GO:0015562|GO:0016021 LH59_21215 407247666a64113c42e36b497030f2ce 1073 PRINTS PR00702 Acriflavin resistance protein family signature 553 570 1.2E-102 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_21215 407247666a64113c42e36b497030f2ce 1073 PRINTS PR00702 Acriflavin resistance protein family signature 391 415 1.2E-102 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_21215 407247666a64113c42e36b497030f2ce 1073 PRINTS PR00702 Acriflavin resistance protein family signature 620 634 1.2E-102 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_21215 407247666a64113c42e36b497030f2ce 1073 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 1.2E-102 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_21215 407247666a64113c42e36b497030f2ce 1073 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 1.2E-102 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_21215 407247666a64113c42e36b497030f2ce 1073 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 1.2E-102 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_21215 407247666a64113c42e36b497030f2ce 1073 PRINTS PR00702 Acriflavin resistance protein family signature 363 384 1.2E-102 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_21215 407247666a64113c42e36b497030f2ce 1073 PRINTS PR00702 Acriflavin resistance protein family signature 336 359 1.2E-102 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_21215 407247666a64113c42e36b497030f2ce 1073 PRINTS PR00702 Acriflavin resistance protein family signature 445 468 1.2E-102 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_21215 407247666a64113c42e36b497030f2ce 1073 Gene3D G3DSA:3.30.70.1440 669 865 0.0 T 14-10-2018 LH59_21215 407247666a64113c42e36b497030f2ce 1073 SUPERFAMILY SSF82866 296 497 8.11E-49 T 14-10-2018 LH59_25940 6d64c1f61d5bde501cf4966cea94bad0 229 Pfam PF01144 Coenzyme A transferase 7 218 7.6E-71 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 LH59_25940 6d64c1f61d5bde501cf4966cea94bad0 229 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 1 220 1.6E-114 T 14-10-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 LH59_25940 6d64c1f61d5bde501cf4966cea94bad0 229 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 18 33 - T 14-10-2018 IPR004163 Coenzyme A transferase binding site GO:0008410 Reactome: R-HSA-77108 LH59_25940 6d64c1f61d5bde501cf4966cea94bad0 229 SMART SM00882 6 219 4.2E-84 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 LH59_25940 6d64c1f61d5bde501cf4966cea94bad0 229 SUPERFAMILY SSF100950 2 220 4.49E-78 T 14-10-2018 IPR037171 NagB/RpiA transferase-like LH59_25940 6d64c1f61d5bde501cf4966cea94bad0 229 Gene3D G3DSA:3.40.1080.10 1 218 2.4E-80 T 14-10-2018 LH59_04815 7bb5e07f46a9886e41f52a0bc6c1620a 247 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 220 238 1.4E-4 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal LH59_04815 7bb5e07f46a9886e41f52a0bc6c1620a 247 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_04815 7bb5e07f46a9886e41f52a0bc6c1620a 247 Pfam PF00005 ABC transporter 22 167 1.6E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_04815 7bb5e07f46a9886e41f52a0bc6c1620a 247 Gene3D G3DSA:3.40.50.300 2 240 4.6E-56 T 14-10-2018 LH59_04815 7bb5e07f46a9886e41f52a0bc6c1620a 247 SMART SM00382 30 239 3.0E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_04815 7bb5e07f46a9886e41f52a0bc6c1620a 247 SUPERFAMILY SSF52540 5 238 5.22E-54 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_15165 c26559b87ff44bcbcdb2f0d0b0fd7f30 550 Gene3D G3DSA:3.50.50.60 5 529 6.6E-188 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_15165 c26559b87ff44bcbcdb2f0d0b0fd7f30 550 Gene3D G3DSA:3.30.410.40 151 470 6.6E-188 T 14-10-2018 LH59_15165 c26559b87ff44bcbcdb2f0d0b0fd7f30 550 SUPERFAMILY SSF51905 2 533 3.72E-93 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_15165 c26559b87ff44bcbcdb2f0d0b0fd7f30 550 Gene3D G3DSA:1.10.1220.110 97 150 6.6E-188 T 14-10-2018 LH59_15165 c26559b87ff44bcbcdb2f0d0b0fd7f30 550 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 82 105 - T 14-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 LH59_15165 c26559b87ff44bcbcdb2f0d0b0fd7f30 550 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 254 268 - T 14-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 LH59_15165 c26559b87ff44bcbcdb2f0d0b0fd7f30 550 SUPERFAMILY SSF54373 290 473 3.83E-62 T 14-10-2018 LH59_15165 c26559b87ff44bcbcdb2f0d0b0fd7f30 550 Pfam PF05199 GMC oxidoreductase 387 525 1.6E-42 T 14-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 LH59_15165 c26559b87ff44bcbcdb2f0d0b0fd7f30 550 Pfam PF00732 GMC oxidoreductase 5 295 1.5E-89 T 14-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 LH59_15165 c26559b87ff44bcbcdb2f0d0b0fd7f30 550 Gene3D G3DSA:4.10.450.10 38 196 6.6E-188 T 14-10-2018 IPR027424 Glucose Oxidase, domain 2 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|Reactome: R-HSA-6798163 LH59_15165 c26559b87ff44bcbcdb2f0d0b0fd7f30 550 PIRSF PIRSF000137 2 540 1.4E-158 T 14-10-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 LH59_00470 fb418db3401d9e1da7590707fa5970cb 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 2.1E-8 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_00470 fb418db3401d9e1da7590707fa5970cb 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 2.1E-8 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_00470 fb418db3401d9e1da7590707fa5970cb 243 SMART SM00345 14 73 1.2E-15 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_00470 fb418db3401d9e1da7590707fa5970cb 243 Pfam PF07729 FCD domain 96 221 1.4E-24 T 14-10-2018 IPR011711 GntR, C-terminal LH59_00470 fb418db3401d9e1da7590707fa5970cb 243 SUPERFAMILY SSF48008 92 227 2.88E-28 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_00470 fb418db3401d9e1da7590707fa5970cb 243 Gene3D G3DSA:1.10.10.10 12 80 9.1E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_00470 fb418db3401d9e1da7590707fa5970cb 243 SUPERFAMILY SSF46785 6 77 5.83E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_00470 fb418db3401d9e1da7590707fa5970cb 243 Gene3D G3DSA:1.20.120.530 87 234 3.6E-30 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_00470 fb418db3401d9e1da7590707fa5970cb 243 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 73 6.5E-18 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_00470 fb418db3401d9e1da7590707fa5970cb 243 SMART SM00895 96 222 4.1E-22 T 14-10-2018 IPR011711 GntR, C-terminal LH59_17355 a576796140f2a4ca58f90fa61b6acc02 518 Pfam PF01565 FAD binding domain 93 231 5.5E-33 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 LH59_17355 a576796140f2a4ca58f90fa61b6acc02 518 SUPERFAMILY SSF55103 243 509 5.76E-35 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 LH59_17355 a576796140f2a4ca58f90fa61b6acc02 518 Gene3D G3DSA:3.40.462.40 311 461 1.2E-16 T 14-10-2018 LH59_17355 a576796140f2a4ca58f90fa61b6acc02 518 Pfam PF02913 FAD linked oxidases, C-terminal domain 268 505 6.6E-30 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 LH59_17355 a576796140f2a4ca58f90fa61b6acc02 518 SUPERFAMILY SSF56176 58 268 5.61E-50 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 LH59_17355 a576796140f2a4ca58f90fa61b6acc02 518 Gene3D G3DSA:1.10.45.10 467 505 7.9E-9 T 14-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 LH59_17355 a576796140f2a4ca58f90fa61b6acc02 518 Gene3D G3DSA:3.30.465.40 65 282 9.0E-56 T 14-10-2018 LH59_12695 7b66cd1accdf41783be58a02eb683ac0 525 PIRSF PIRSF006060 7 499 3.3E-81 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 LH59_12695 7b66cd1accdf41783be58a02eb683ac0 525 Gene3D G3DSA:1.20.1740.10 20 487 2.1E-62 T 14-10-2018 LH59_12695 7b66cd1accdf41783be58a02eb683ac0 525 Pfam PF00324 Amino acid permease 29 478 2.7E-135 T 14-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 LH59_12695 7b66cd1accdf41783be58a02eb683ac0 525 ProSitePatterns PS00218 Amino acid permeases signature. 54 85 - T 14-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 LH59_04615 4a4527c6f3871979fa19cec8897839af 326 Pfam PF03547 Membrane transport protein 178 319 2.4E-11 T 14-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 LH59_04615 4a4527c6f3871979fa19cec8897839af 326 Gene3D G3DSA:1.20.1530.20 188 326 1.3E-5 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily LH59_00625 7caaf9b2032f5f77a87c99ddf7a0d0e7 403 Gene3D G3DSA:3.40.50.2300 149 280 1.1E-109 T 14-10-2018 LH59_00625 7caaf9b2032f5f77a87c99ddf7a0d0e7 403 Pfam PF13458 Periplasmic binding protein 30 366 8.0E-85 T 14-10-2018 IPR028081 Leucine-binding protein domain LH59_00625 7caaf9b2032f5f77a87c99ddf7a0d0e7 403 Gene3D G3DSA:3.40.50.2300 33 341 1.1E-109 T 14-10-2018 LH59_00625 7caaf9b2032f5f77a87c99ddf7a0d0e7 403 SUPERFAMILY SSF53822 30 401 8.07E-89 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_13150 b25cddae03b1469f2b9b05c4713f7828 456 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 422 442 5.6E-7 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 LH59_13150 b25cddae03b1469f2b9b05c4713f7828 456 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 405 422 5.6E-7 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 LH59_13150 b25cddae03b1469f2b9b05c4713f7828 456 Pfam PF00158 Sigma-54 interaction domain 137 302 9.9E-70 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 LH59_13150 b25cddae03b1469f2b9b05c4713f7828 456 SUPERFAMILY SSF52540 136 377 6.65E-72 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_13150 b25cddae03b1469f2b9b05c4713f7828 456 Gene3D G3DSA:3.40.50.300 129 307 5.1E-66 T 14-10-2018 LH59_13150 b25cddae03b1469f2b9b05c4713f7828 456 Pfam PF02954 Bacterial regulatory protein, Fis family 398 439 4.9E-14 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 LH59_13150 b25cddae03b1469f2b9b05c4713f7828 456 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 222 237 - T 14-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 LH59_13150 b25cddae03b1469f2b9b05c4713f7828 456 Gene3D G3DSA:3.40.50.2300 3 118 3.6E-28 T 14-10-2018 LH59_13150 b25cddae03b1469f2b9b05c4713f7828 456 SUPERFAMILY SSF46689 348 439 9.56E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_13150 b25cddae03b1469f2b9b05c4713f7828 456 Pfam PF00072 Response regulator receiver domain 5 108 2.2E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_13150 b25cddae03b1469f2b9b05c4713f7828 456 Gene3D G3DSA:1.10.8.60 308 383 4.4E-23 T 14-10-2018 LH59_13150 b25cddae03b1469f2b9b05c4713f7828 456 SUPERFAMILY SSF52172 1 181 2.56E-35 T 14-10-2018 IPR011006 CheY-like superfamily LH59_13150 b25cddae03b1469f2b9b05c4713f7828 456 Gene3D G3DSA:1.10.10.60 384 442 3.8E-13 T 14-10-2018 LH59_13150 b25cddae03b1469f2b9b05c4713f7828 456 SMART SM00382 156 300 4.8E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_13150 b25cddae03b1469f2b9b05c4713f7828 456 SMART SM00448 2 111 2.1E-29 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_13150 b25cddae03b1469f2b9b05c4713f7828 456 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 348 357 - T 14-10-2018 IPR025944 Sigma-54 interaction domain, conserved site LH59_00345 eb071c2dc14ad2731b962020e955d66f 293 Gene3D G3DSA:3.40.50.620 78 228 2.0E-89 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LH59_00345 eb071c2dc14ad2731b962020e955d66f 293 SUPERFAMILY SSF52374 3 266 5.9E-75 T 14-10-2018 LH59_00345 eb071c2dc14ad2731b962020e955d66f 293 Hamap MF_01428 Glutamyl-Q tRNA(Asp) synthetase [gluQ]. 3 293 43.02 T 14-10-2018 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0004812|GO:0006400 LH59_00345 eb071c2dc14ad2731b962020e955d66f 293 PRINTS PR00987 Glutamyl-tRNA synthetase signature 35 48 1.6E-13 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 LH59_00345 eb071c2dc14ad2731b962020e955d66f 293 PRINTS PR00987 Glutamyl-tRNA synthetase signature 196 204 1.6E-13 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 LH59_00345 eb071c2dc14ad2731b962020e955d66f 293 PRINTS PR00987 Glutamyl-tRNA synthetase signature 180 190 1.6E-13 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 LH59_00345 eb071c2dc14ad2731b962020e955d66f 293 PRINTS PR00987 Glutamyl-tRNA synthetase signature 6 18 1.6E-13 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 LH59_00345 eb071c2dc14ad2731b962020e955d66f 293 PRINTS PR00987 Glutamyl-tRNA synthetase signature 20 31 1.6E-13 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 LH59_00345 eb071c2dc14ad2731b962020e955d66f 293 Gene3D G3DSA:3.40.50.620 3 287 2.0E-89 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LH59_00345 eb071c2dc14ad2731b962020e955d66f 293 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 6 246 1.1E-35 T 14-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 LH59_00345 eb071c2dc14ad2731b962020e955d66f 293 TIGRFAM TIGR03838 queuosine_YadB: glutamyl-queuosine tRNA(Asp) synthetase 3 273 8.8E-110 T 14-10-2018 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0004812|GO:0006400 LH59_00315 9d2a39d499739678503f30e7d033d718 266 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 28 263 2.7E-60 T 14-10-2018 LH59_00315 9d2a39d499739678503f30e7d033d718 266 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 157 185 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LH59_00315 9d2a39d499739678503f30e7d033d718 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 158 1.5E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_00315 9d2a39d499739678503f30e7d033d718 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 170 189 1.5E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_00315 9d2a39d499739678503f30e7d033d718 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 97 108 1.5E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_00315 9d2a39d499739678503f30e7d033d718 266 SUPERFAMILY SSF51735 17 264 5.75E-77 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_00315 9d2a39d499739678503f30e7d033d718 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 97 108 4.0E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_00315 9d2a39d499739678503f30e7d033d718 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 226 246 4.0E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_00315 9d2a39d499739678503f30e7d033d718 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 191 208 4.0E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_00315 9d2a39d499739678503f30e7d033d718 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 160 4.0E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_00315 9d2a39d499739678503f30e7d033d718 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 23 40 4.0E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_00315 9d2a39d499739678503f30e7d033d718 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 189 4.0E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_00315 9d2a39d499739678503f30e7d033d718 266 Gene3D G3DSA:3.40.50.720 13 265 2.5E-78 T 14-10-2018 LH59_00315 9d2a39d499739678503f30e7d033d718 266 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 22 206 9.9E-4 T 14-10-2018 LH59_23200 8ac76fa2b282222f09fbc3cb1c853096 169 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 163 5.5E-23 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 LH59_23200 8ac76fa2b282222f09fbc3cb1c853096 169 Pfam PF08281 Sigma-70, region 4 111 164 1.0E-14 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LH59_23200 8ac76fa2b282222f09fbc3cb1c853096 169 SUPERFAMILY SSF88946 10 101 7.46E-20 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 LH59_23200 8ac76fa2b282222f09fbc3cb1c853096 169 Pfam PF04542 Sigma-70 region 2 15 81 7.8E-17 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 LH59_23200 8ac76fa2b282222f09fbc3cb1c853096 169 Gene3D G3DSA:1.10.10.10 106 165 6.5E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_23200 8ac76fa2b282222f09fbc3cb1c853096 169 SUPERFAMILY SSF88659 106 164 3.4E-11 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like LH59_23200 8ac76fa2b282222f09fbc3cb1c853096 169 Gene3D G3DSA:1.10.1740.10 2 78 6.7E-13 T 14-10-2018 LH59_02990 ba2db9ae5be10d3f7d5b157562d330b9 177 SUPERFAMILY SSF54427 20 175 4.27E-46 T 14-10-2018 IPR032710 NTF2-like domain superfamily LH59_02990 ba2db9ae5be10d3f7d5b157562d330b9 177 Pfam PF00866 Ring hydroxylating beta subunit 33 165 3.4E-32 T 14-10-2018 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0006725|GO:0055114 LH59_02990 ba2db9ae5be10d3f7d5b157562d330b9 177 Gene3D G3DSA:3.10.450.50 2 173 4.3E-49 T 14-10-2018 LH59_04385 2bd397122520b3fb5dab667f34a37aa2 380 SUPERFAMILY SSF110738 2 373 1.02E-129 T 14-10-2018 IPR036129 Glycerate kinase superfamily GO:0008887|GO:0031388 LH59_04385 2bd397122520b3fb5dab667f34a37aa2 380 Gene3D G3DSA:3.40.50.10350 2 361 8.0E-136 T 14-10-2018 IPR018197 Glycerate kinase, restriction-enzyme-like fold LH59_04385 2bd397122520b3fb5dab667f34a37aa2 380 PIRSF PIRSF006078 1 377 8.3E-129 T 14-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 LH59_04385 2bd397122520b3fb5dab667f34a37aa2 380 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 2 373 1.7E-145 T 14-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 LH59_04385 2bd397122520b3fb5dab667f34a37aa2 380 Gene3D G3DSA:3.90.1510.10 42 275 8.0E-136 T 14-10-2018 IPR018193 Glycerate kinase, flavodoxin-like fold GO:0008887|GO:0031388 LH59_04385 2bd397122520b3fb5dab667f34a37aa2 380 Pfam PF02595 Glycerate kinase family 3 372 1.3E-142 T 14-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 LH59_00215 5a99bbccb87ffe915740178bb4da724c 387 SUPERFAMILY SSF51905 10 372 2.27E-54 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_00215 5a99bbccb87ffe915740178bb4da724c 387 Gene3D G3DSA:3.50.50.60 10 359 5.5E-91 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_00215 5a99bbccb87ffe915740178bb4da724c 387 Pfam PF01266 FAD dependent oxidoreductase 10 353 4.6E-62 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 LH59_00215 5a99bbccb87ffe915740178bb4da724c 387 Gene3D G3DSA:3.30.9.10 88 316 5.5E-91 T 14-10-2018 LH59_04285 5ee63a12432d114fd8f6687c7f9bb35a 531 SUPERFAMILY SSF103190 183 262 1.84E-8 T 14-10-2018 IPR029151 Periplasmic sensor-like domain superfamily LH59_04285 5ee63a12432d114fd8f6687c7f9bb35a 531 Gene3D G3DSA:3.30.450.20 32 175 9.4E-12 T 14-10-2018 LH59_04285 5ee63a12432d114fd8f6687c7f9bb35a 531 Pfam PF00990 Diguanylate cyclase, GGDEF domain 362 512 3.7E-40 T 14-10-2018 IPR000160 GGDEF domain LH59_04285 5ee63a12432d114fd8f6687c7f9bb35a 531 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 358 517 1.3E-44 T 14-10-2018 IPR000160 GGDEF domain LH59_04285 5ee63a12432d114fd8f6687c7f9bb35a 531 Pfam PF02743 Cache domain 95 263 1.1E-20 T 14-10-2018 IPR033479 Double Cache domain 1 LH59_04285 5ee63a12432d114fd8f6687c7f9bb35a 531 SMART SM00267 350 517 4.6E-54 T 14-10-2018 IPR000160 GGDEF domain LH59_04285 5ee63a12432d114fd8f6687c7f9bb35a 531 SUPERFAMILY SSF103190 91 172 2.71E-5 T 14-10-2018 IPR029151 Periplasmic sensor-like domain superfamily LH59_04285 5ee63a12432d114fd8f6687c7f9bb35a 531 SUPERFAMILY SSF55073 366 519 1.18E-45 T 14-10-2018 IPR029787 Nucleotide cyclase LH59_04285 5ee63a12432d114fd8f6687c7f9bb35a 531 Gene3D G3DSA:3.30.70.270 348 517 1.9E-51 T 14-10-2018 LH59_20315 f532b464c91c53dc349453cc29e7b226 214 SUPERFAMILY SSF48150 35 207 3.49E-43 T 14-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 LH59_20315 f532b464c91c53dc349453cc29e7b226 214 Gene3D G3DSA:1.10.1670.40 19 205 8.4E-61 T 14-10-2018 LH59_20315 f532b464c91c53dc349453cc29e7b226 214 SMART SM00478 55 208 5.6E-16 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 LH59_20315 f532b464c91c53dc349453cc29e7b226 214 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 52 177 1.4E-10 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 LH59_20315 f532b464c91c53dc349453cc29e7b226 214 Gene3D G3DSA:1.10.340.30 45 155 8.4E-61 T 14-10-2018 LH59_09320 4f9e419ab3bfe7bfeeb635af45d6f403 327 Gene3D G3DSA:1.20.120.1460 236 304 2.9E-15 T 14-10-2018 LH59_09320 4f9e419ab3bfe7bfeeb635af45d6f403 327 Pfam PF01207 Dihydrouridine synthase (Dus) 1 289 1.1E-69 T 14-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 LH59_09320 4f9e419ab3bfe7bfeeb635af45d6f403 327 PIRSF PIRSF006621 1 288 5.5E-62 T 14-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 LH59_09320 4f9e419ab3bfe7bfeeb635af45d6f403 327 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 77 95 - T 14-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 LH59_09320 4f9e419ab3bfe7bfeeb635af45d6f403 327 SUPERFAMILY SSF51395 1 289 2.15E-60 T 14-10-2018 LH59_09320 4f9e419ab3bfe7bfeeb635af45d6f403 327 Hamap MF_02041 tRNA-dihydrouridine(20/20a) synthase [dusA]. 1 310 42.912 T 14-10-2018 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 LH59_09320 4f9e419ab3bfe7bfeeb635af45d6f403 327 Gene3D G3DSA:3.20.20.70 1 233 8.7E-64 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_22320 3a19393781bf027bb397f5a0f49136dc 396 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 15 379 3.0E-117 T 14-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 LH59_22320 3a19393781bf027bb397f5a0f49136dc 396 Gene3D G3DSA:3.30.1490.20 120 186 1.6E-20 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 LH59_22320 3a19393781bf027bb397f5a0f49136dc 396 Gene3D G3DSA:3.40.50.20 8 119 3.6E-40 T 14-10-2018 LH59_22320 3a19393781bf027bb397f5a0f49136dc 396 Pfam PF02222 ATP-grasp domain 120 291 8.4E-46 T 14-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type LH59_22320 3a19393781bf027bb397f5a0f49136dc 396 SUPERFAMILY SSF56059 110 311 1.6E-55 T 14-10-2018 LH59_22320 3a19393781bf027bb397f5a0f49136dc 396 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 14 376 40.839 T 14-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 LH59_22320 3a19393781bf027bb397f5a0f49136dc 396 SUPERFAMILY SSF52440 11 107 4.89E-26 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily LH59_22320 3a19393781bf027bb397f5a0f49136dc 396 SUPERFAMILY SSF51246 315 390 1.02E-16 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 LH59_22320 3a19393781bf027bb397f5a0f49136dc 396 Gene3D G3DSA:3.30.470.20 188 392 1.3E-78 T 14-10-2018 LH59_07730 82a67a8e01edec8847c6089f5c7309b1 189 SUPERFAMILY SSF109604 6 63 1.08E-8 T 14-10-2018 LH59_07730 82a67a8e01edec8847c6089f5c7309b1 189 Gene3D G3DSA:1.10.3210.10 2 184 2.2E-54 T 14-10-2018 LH59_07730 82a67a8e01edec8847c6089f5c7309b1 189 TIGRFAM TIGR03276 Phn-HD: phosphonate degradation operons associated HDIG domain protein 3 178 8.4E-75 T 14-10-2018 IPR017670 Phosphonate degradation operon associated HDIG domain protein LH59_18805 17bd81bb6b1353cf8914f4ceb3e8a057 364 SUPERFAMILY SSF53850 137 268 1.67E-6 T 14-10-2018 LH59_18805 17bd81bb6b1353cf8914f4ceb3e8a057 364 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 56 318 1.2E-32 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 LH59_18805 17bd81bb6b1353cf8914f4ceb3e8a057 364 Gene3D G3DSA:3.40.190.170 30 350 1.1E-65 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily LH59_28255 5f5c62b5a2ba2a444f751f4a27ab7c46 44 Pfam PF00468 Ribosomal protein L34 1 44 8.0E-23 T 14-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_28255 5f5c62b5a2ba2a444f751f4a27ab7c46 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 42 6.0E-16 T 14-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_28255 5f5c62b5a2ba2a444f751f4a27ab7c46 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 15.935 T 14-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_28255 5f5c62b5a2ba2a444f751f4a27ab7c46 44 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 14-10-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_28255 5f5c62b5a2ba2a444f751f4a27ab7c46 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 44 3.5E-24 T 14-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_07190 2dea0204c45d73df87a7986f80347da1 491 SUPERFAMILY SSF56801 15 481 7.98E-100 T 14-10-2018 LH59_07190 2dea0204c45d73df87a7986f80347da1 491 ProSitePatterns PS00455 Putative AMP-binding domain signature. 130 141 - T 14-10-2018 IPR020845 AMP-binding, conserved site LH59_07190 2dea0204c45d73df87a7986f80347da1 491 Pfam PF00501 AMP-binding enzyme 119 376 4.6E-52 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 LH59_07190 2dea0204c45d73df87a7986f80347da1 491 Pfam PF00501 AMP-binding enzyme 16 100 1.2E-5 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 LH59_07190 2dea0204c45d73df87a7986f80347da1 491 Gene3D G3DSA:3.30.300.30 370 484 5.3E-24 T 14-10-2018 LH59_07190 2dea0204c45d73df87a7986f80347da1 491 Gene3D G3DSA:3.40.50.12780 9 369 3.1E-84 T 14-10-2018 LH59_25465 1d219868d301ffb6f7a89c4edc770740 279 SUPERFAMILY SSF46785 22 91 2.36E-7 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_25465 1d219868d301ffb6f7a89c4edc770740 279 SMART SM00346 21 108 2.8E-12 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_25465 1d219868d301ffb6f7a89c4edc770740 279 Pfam PF01614 Bacterial transcriptional regulator 138 261 1.1E-19 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal LH59_25465 1d219868d301ffb6f7a89c4edc770740 279 Pfam PF09339 IclR helix-turn-helix domain 23 70 2.9E-8 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_25465 1d219868d301ffb6f7a89c4edc770740 279 Gene3D G3DSA:3.30.450.40 93 268 1.0E-52 T 14-10-2018 IPR029016 GAF-like domain superfamily LH59_25465 1d219868d301ffb6f7a89c4edc770740 279 SUPERFAMILY SSF55781 84 265 1.31E-44 T 14-10-2018 LH59_25465 1d219868d301ffb6f7a89c4edc770740 279 Gene3D G3DSA:1.10.10.10 15 88 7.1E-11 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_12395 b6454b7bf7f9ef2116a873e4b2ab8dcc 501 SUPERFAMILY SSF53335 62 435 3.98E-78 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_12395 b6454b7bf7f9ef2116a873e4b2ab8dcc 501 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 363 397 - T 14-10-2018 IPR030390 RNA methyltransferase TrmA, active site LH59_12395 b6454b7bf7f9ef2116a873e4b2ab8dcc 501 Gene3D G3DSA:2.40.50.140 3 73 8.5E-24 T 14-10-2018 LH59_12395 b6454b7bf7f9ef2116a873e4b2ab8dcc 501 Gene3D G3DSA:3.40.1350.30 121 263 1.1E-101 T 14-10-2018 LH59_12395 b6454b7bf7f9ef2116a873e4b2ab8dcc 501 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 419 429 - T 14-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site LH59_12395 b6454b7bf7f9ef2116a873e4b2ab8dcc 501 SUPERFAMILY SSF50249 5 59 1.09E-11 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_12395 b6454b7bf7f9ef2116a873e4b2ab8dcc 501 Gene3D G3DSA:3.40.50.150 74 431 1.1E-101 T 14-10-2018 LH59_12395 b6454b7bf7f9ef2116a873e4b2ab8dcc 501 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 10 429 1.6E-91 T 14-10-2018 LH59_12395 b6454b7bf7f9ef2116a873e4b2ab8dcc 501 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 255 431 1.7E-14 T 14-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 LH59_12395 b6454b7bf7f9ef2116a873e4b2ab8dcc 501 Hamap MF_01010 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD [rlmD]. 4 437 68.839 T 14-10-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 LH59_24415 15d1dea6e4b1f08a0017641f337a4de6 268 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 18 227 3.6E-19 T 14-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 LH59_24415 15d1dea6e4b1f08a0017641f337a4de6 268 SUPERFAMILY SSF56784 13 260 2.18E-28 T 14-10-2018 IPR036412 HAD-like superfamily LH59_24415 15d1dea6e4b1f08a0017641f337a4de6 268 Gene3D G3DSA:3.40.50.1000 13 128 8.8E-12 T 14-10-2018 IPR023214 HAD superfamily LH59_24415 15d1dea6e4b1f08a0017641f337a4de6 268 Pfam PF08282 haloacid dehalogenase-like hydrolase 18 84 2.9E-6 T 14-10-2018 LH59_24415 15d1dea6e4b1f08a0017641f337a4de6 268 Gene3D G3DSA:3.40.50.1000 153 268 1.6E-6 T 14-10-2018 IPR023214 HAD superfamily LH59_00720 a535211290a6da585c6bc00724c9381b 93 Pfam PF04324 BFD-like [2Fe-2S] binding domain 2 49 9.9E-10 T 14-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain LH59_00720 a535211290a6da585c6bc00724c9381b 93 Gene3D G3DSA:1.10.10.1100 1 51 6.3E-18 T 14-10-2018 LH59_08865 2ebf3de97ae17d3d818562a09d5b9eb0 303 SUPERFAMILY SSF102886 8 303 6.8E-131 T 14-10-2018 IPR036406 Oxygen-dependent coproporphyrinogen III oxidase superfamily GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 LH59_08865 2ebf3de97ae17d3d818562a09d5b9eb0 303 PRINTS PR00073 Coprogen oxidase signature 89 113 8.4E-80 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 LH59_08865 2ebf3de97ae17d3d818562a09d5b9eb0 303 PRINTS PR00073 Coprogen oxidase signature 47 68 8.4E-80 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 LH59_08865 2ebf3de97ae17d3d818562a09d5b9eb0 303 PRINTS PR00073 Coprogen oxidase signature 236 263 8.4E-80 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 LH59_08865 2ebf3de97ae17d3d818562a09d5b9eb0 303 PRINTS PR00073 Coprogen oxidase signature 127 149 8.4E-80 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 LH59_08865 2ebf3de97ae17d3d818562a09d5b9eb0 303 PRINTS PR00073 Coprogen oxidase signature 264 290 8.4E-80 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 LH59_08865 2ebf3de97ae17d3d818562a09d5b9eb0 303 PRINTS PR00073 Coprogen oxidase signature 30 46 8.4E-80 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 LH59_08865 2ebf3de97ae17d3d818562a09d5b9eb0 303 PRINTS PR00073 Coprogen oxidase signature 164 193 8.4E-80 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 LH59_08865 2ebf3de97ae17d3d818562a09d5b9eb0 303 Hamap MF_00333 Oxygen-dependent coproporphyrinogen-III oxidase [hemF]. 3 279 52.838 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 LH59_08865 2ebf3de97ae17d3d818562a09d5b9eb0 303 PIRSF PIRSF000166 5 303 3.9E-120 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 LH59_08865 2ebf3de97ae17d3d818562a09d5b9eb0 303 ProSitePatterns PS01021 Coproporphyrinogen III oxidase signature. 168 192 - T 14-10-2018 IPR018375 Coproporphyrinogen III oxidase, conserved site GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 LH59_08865 2ebf3de97ae17d3d818562a09d5b9eb0 303 Pfam PF01218 Coproporphyrinogen III oxidase 10 303 7.5E-126 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 LH59_08865 2ebf3de97ae17d3d818562a09d5b9eb0 303 Gene3D G3DSA:3.40.1500.10 2 303 4.5E-128 T 14-10-2018 IPR036406 Oxygen-dependent coproporphyrinogen III oxidase superfamily GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 LH59_18560 ec6f93d8fbda0309e0793135c49878c2 371 SUPERFAMILY SSF52540 25 262 1.61E-81 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_18560 ec6f93d8fbda0309e0793135c49878c2 371 SMART SM00930 291 364 0.0012 T 14-10-2018 IPR018449 NIL domain LH59_18560 ec6f93d8fbda0309e0793135c49878c2 371 SMART SM00382 53 240 5.0E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_18560 ec6f93d8fbda0309e0793135c49878c2 371 Pfam PF09383 NIL domain 294 359 1.2E-5 T 14-10-2018 IPR018449 NIL domain LH59_18560 ec6f93d8fbda0309e0793135c49878c2 371 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_18560 ec6f93d8fbda0309e0793135c49878c2 371 Gene3D G3DSA:3.40.50.300 24 282 2.4E-83 T 14-10-2018 LH59_18560 ec6f93d8fbda0309e0793135c49878c2 371 Pfam PF00005 ABC transporter 44 192 2.2E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_18560 ec6f93d8fbda0309e0793135c49878c2 371 SUPERFAMILY SSF55021 290 366 4.69E-5 T 14-10-2018 LH59_14965 93391c2d49aa6050f2d18806e25edf12 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 3.4E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_14965 93391c2d49aa6050f2d18806e25edf12 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 3.4E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_14965 93391c2d49aa6050f2d18806e25edf12 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 3.4E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_14965 93391c2d49aa6050f2d18806e25edf12 264 Gene3D G3DSA:3.40.50.720 2 262 8.9E-83 T 14-10-2018 LH59_14965 93391c2d49aa6050f2d18806e25edf12 264 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 23 258 1.5E-66 T 14-10-2018 LH59_14965 93391c2d49aa6050f2d18806e25edf12 264 SUPERFAMILY SSF51735 6 260 2.89E-80 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_14965 93391c2d49aa6050f2d18806e25edf12 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 9.5E-33 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_14965 93391c2d49aa6050f2d18806e25edf12 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 9.5E-33 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_14965 93391c2d49aa6050f2d18806e25edf12 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 9.5E-33 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_14965 93391c2d49aa6050f2d18806e25edf12 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 9.5E-33 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_14965 93391c2d49aa6050f2d18806e25edf12 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 9.5E-33 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25945 e85fa6e601dcad8d50fff3b2d3a4e024 214 SMART SM00882 8 205 1.6E-66 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 LH59_25945 e85fa6e601dcad8d50fff3b2d3a4e024 214 Pfam PF01144 Coenzyme A transferase 8 184 3.0E-37 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 LH59_25945 e85fa6e601dcad8d50fff3b2d3a4e024 214 SUPERFAMILY SSF100950 6 213 1.09E-65 T 14-10-2018 IPR037171 NagB/RpiA transferase-like LH59_25945 e85fa6e601dcad8d50fff3b2d3a4e024 214 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 6 210 5.4E-90 T 14-10-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 LH59_25945 e85fa6e601dcad8d50fff3b2d3a4e024 214 Gene3D G3DSA:3.40.1080.10 2 214 5.3E-85 T 14-10-2018 LH59_00060 6a1bf54837b1245121249c6f892db07f 302 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 36 267 1.3E-42 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_00060 6a1bf54837b1245121249c6f892db07f 302 Gene3D G3DSA:3.40.190.10 129 226 2.7E-80 T 14-10-2018 LH59_00060 6a1bf54837b1245121249c6f892db07f 302 Gene3D G3DSA:3.40.190.10 26 272 2.7E-80 T 14-10-2018 LH59_00060 6a1bf54837b1245121249c6f892db07f 302 SUPERFAMILY SSF53850 1 270 3.09E-55 T 14-10-2018 LH59_00060 6a1bf54837b1245121249c6f892db07f 302 SMART SM00062 35 269 6.2E-43 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_13685 a1c942165e0a7903bae15589ba4c917f 422 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 90 110 4.8E-22 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 LH59_13685 a1c942165e0a7903bae15589ba4c917f 422 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 111 131 4.8E-22 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 LH59_13685 a1c942165e0a7903bae15589ba4c917f 422 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 69 84 4.8E-22 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 LH59_13685 a1c942165e0a7903bae15589ba4c917f 422 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 159 185 4.8E-22 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 LH59_13685 a1c942165e0a7903bae15589ba4c917f 422 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 198 220 4.8E-22 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 LH59_13685 a1c942165e0a7903bae15589ba4c917f 422 Pfam PF00355 Rieske [2Fe-2S] domain 54 137 1.4E-17 T 14-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 LH59_13685 a1c942165e0a7903bae15589ba4c917f 422 SUPERFAMILY SSF55961 184 420 5.65E-46 T 14-10-2018 LH59_13685 a1c942165e0a7903bae15589ba4c917f 422 Gene3D G3DSA:3.90.380.10 30 420 8.9E-84 T 14-10-2018 LH59_13685 a1c942165e0a7903bae15589ba4c917f 422 SUPERFAMILY SSF50022 21 175 1.02E-44 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 LH59_13685 a1c942165e0a7903bae15589ba4c917f 422 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 97 120 - T 14-10-2018 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0051537|GO:0055114 LH59_13685 a1c942165e0a7903bae15589ba4c917f 422 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 210 420 4.7E-17 T 14-10-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0044237|GO:0051537|GO:0055114 LH59_13685 a1c942165e0a7903bae15589ba4c917f 422 Gene3D G3DSA:2.102.10.10 54 183 8.9E-84 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 LH59_15220 0374c8c46ed9d328a68f40e1b992b8bd 268 Pfam PF02311 AraC-like ligand binding domain 31 106 9.9E-8 T 14-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 LH59_15220 0374c8c46ed9d328a68f40e1b992b8bd 268 SUPERFAMILY SSF46689 216 263 5.82E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_15220 0374c8c46ed9d328a68f40e1b992b8bd 268 Gene3D G3DSA:2.60.120.10 20 127 2.0E-5 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_15220 0374c8c46ed9d328a68f40e1b992b8bd 268 SMART SM00342 179 261 1.2E-21 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_15220 0374c8c46ed9d328a68f40e1b992b8bd 268 Gene3D G3DSA:1.10.10.60 222 267 3.3E-8 T 14-10-2018 LH59_15220 0374c8c46ed9d328a68f40e1b992b8bd 268 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 216 257 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 LH59_15220 0374c8c46ed9d328a68f40e1b992b8bd 268 Pfam PF12833 Helix-turn-helix domain 185 262 1.9E-22 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_15220 0374c8c46ed9d328a68f40e1b992b8bd 268 SUPERFAMILY SSF51182 37 194 4.89E-11 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_15220 0374c8c46ed9d328a68f40e1b992b8bd 268 Gene3D G3DSA:1.10.10.60 161 221 7.4E-11 T 14-10-2018 LH59_09895 202d64ebc3fec02610e578dbbac1f29a 894 SUPERFAMILY SSF53955 61 270 3.66E-73 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily LH59_09895 202d64ebc3fec02610e578dbbac1f29a 894 SUPERFAMILY SSF56601 230 757 1.23E-115 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like LH59_09895 202d64ebc3fec02610e578dbbac1f29a 894 Gene3D G3DSA:1.10.3810.10 68 265 7.1E-73 T 14-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 LH59_09895 202d64ebc3fec02610e578dbbac1f29a 894 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 84 734 1.2E-167 T 14-10-2018 LH59_09895 202d64ebc3fec02610e578dbbac1f29a 894 Pfam PF00905 Penicillin binding protein transpeptidase domain 450 703 2.2E-37 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 LH59_09895 202d64ebc3fec02610e578dbbac1f29a 894 Pfam PF17092 Penicillin-binding protein OB-like domain 339 446 3.7E-17 T 14-10-2018 IPR031376 Penicillin-binding protein, OB-like domain KEGG: 00550+2.4.1.129+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 LH59_09895 202d64ebc3fec02610e578dbbac1f29a 894 Pfam PF00912 Transglycosylase 76 249 3.6E-61 T 14-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 LH59_09895 202d64ebc3fec02610e578dbbac1f29a 894 Gene3D G3DSA:2.40.50.140 374 445 2.1E-18 T 14-10-2018 LH59_21155 e4fb31ac73688e65ed60aeef3e98597d 439 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 254 430 3.4E-83 T 14-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 LH59_21155 e4fb31ac73688e65ed60aeef3e98597d 439 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 9 253 7.5E-111 T 14-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 LH59_21155 e4fb31ac73688e65ed60aeef3e98597d 439 PIRSF PIRSF001362 1 433 1.3E-239 T 14-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 LH59_21155 e4fb31ac73688e65ed60aeef3e98597d 439 Pfam PF00463 Isocitrate lyase family 254 430 9.5E-47 T 14-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 LH59_21155 e4fb31ac73688e65ed60aeef3e98597d 439 Pfam PF00463 Isocitrate lyase family 13 253 3.4E-58 T 14-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 LH59_21155 e4fb31ac73688e65ed60aeef3e98597d 439 ProSitePatterns PS00161 Isocitrate lyase signature. 191 196 - T 14-10-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824 LH59_21155 e4fb31ac73688e65ed60aeef3e98597d 439 Gene3D G3DSA:3.20.20.60 4 413 1.4E-170 T 14-10-2018 LH59_21155 e4fb31ac73688e65ed60aeef3e98597d 439 SUPERFAMILY SSF51621 6 430 1.26E-157 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 LH59_08020 ef3abc90a77e01c9b433d03d6256a56f 314 Gene3D G3DSA:3.40.190.10 8 210 8.5E-82 T 14-10-2018 LH59_08020 ef3abc90a77e01c9b433d03d6256a56f 314 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 7 297 1.8E-107 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LH59_08020 ef3abc90a77e01c9b433d03d6256a56f 314 PRINTS PR00151 Porphobilinogen deaminase signature 125 142 4.0E-43 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LH59_08020 ef3abc90a77e01c9b433d03d6256a56f 314 PRINTS PR00151 Porphobilinogen deaminase signature 231 248 4.0E-43 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LH59_08020 ef3abc90a77e01c9b433d03d6256a56f 314 PRINTS PR00151 Porphobilinogen deaminase signature 144 161 4.0E-43 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LH59_08020 ef3abc90a77e01c9b433d03d6256a56f 314 PRINTS PR00151 Porphobilinogen deaminase signature 46 66 4.0E-43 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LH59_08020 ef3abc90a77e01c9b433d03d6256a56f 314 PRINTS PR00151 Porphobilinogen deaminase signature 77 96 4.0E-43 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LH59_08020 ef3abc90a77e01c9b433d03d6256a56f 314 Gene3D G3DSA:3.30.160.40 224 307 8.5E-26 T 14-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LH59_08020 ef3abc90a77e01c9b433d03d6256a56f 314 SUPERFAMILY SSF53850 6 220 7.44E-81 T 14-10-2018 LH59_08020 ef3abc90a77e01c9b433d03d6256a56f 314 SUPERFAMILY SSF54782 221 310 2.35E-24 T 14-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LH59_08020 ef3abc90a77e01c9b433d03d6256a56f 314 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 7 213 8.4E-76 T 14-10-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LH59_08020 ef3abc90a77e01c9b433d03d6256a56f 314 Gene3D G3DSA:3.40.190.10 104 203 8.5E-82 T 14-10-2018 LH59_08020 ef3abc90a77e01c9b433d03d6256a56f 314 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 6 298 37.739 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LH59_08020 ef3abc90a77e01c9b433d03d6256a56f 314 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 229 296 3.9E-18 T 14-10-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LH59_08020 ef3abc90a77e01c9b433d03d6256a56f 314 PIRSF PIRSF001438 2 312 4.6E-116 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LH59_08020 ef3abc90a77e01c9b433d03d6256a56f 314 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 232 248 - T 14-10-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LH59_01130 472c0d087e3aa346a2cc39bf0e2439f2 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 147 159 7.1E-122 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_01130 472c0d087e3aa346a2cc39bf0e2439f2 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 205 224 7.1E-122 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_01130 472c0d087e3aa346a2cc39bf0e2439f2 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 256 277 7.1E-122 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_01130 472c0d087e3aa346a2cc39bf0e2439f2 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 389 408 7.1E-122 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_01130 472c0d087e3aa346a2cc39bf0e2439f2 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 326 347 7.1E-122 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_01130 472c0d087e3aa346a2cc39bf0e2439f2 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 30 55 7.1E-122 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_01130 472c0d087e3aa346a2cc39bf0e2439f2 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 77 100 7.1E-122 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_01130 472c0d087e3aa346a2cc39bf0e2439f2 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 104 128 7.1E-122 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_01130 472c0d087e3aa346a2cc39bf0e2439f2 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 176 194 7.1E-122 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_01130 472c0d087e3aa346a2cc39bf0e2439f2 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 302 317 7.1E-122 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_01130 472c0d087e3aa346a2cc39bf0e2439f2 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 361 379 7.1E-122 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_01130 472c0d087e3aa346a2cc39bf0e2439f2 535 PRINTS PR01165 Cytochrome c oxidase subunit I signature 439 460 7.1E-122 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_01130 472c0d087e3aa346a2cc39bf0e2439f2 535 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 31 534 7.7E-218 T 14-10-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005886|GO:0015990|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 LH59_01130 472c0d087e3aa346a2cc39bf0e2439f2 535 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 258 312 - T 14-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_01130 472c0d087e3aa346a2cc39bf0e2439f2 535 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 39 480 4.8E-156 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_01130 472c0d087e3aa346a2cc39bf0e2439f2 535 SUPERFAMILY SSF81442 27 534 1.11E-195 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_01130 472c0d087e3aa346a2cc39bf0e2439f2 535 Gene3D G3DSA:1.20.210.10 18 535 2.6E-223 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_08680 f35509d2a9583e274f696d94a100af2e 226 Gene3D G3DSA:3.30.70.260 130 201 1.3E-69 T 14-10-2018 LH59_08680 f35509d2a9583e274f696d94a100af2e 226 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 4 222 32.901 T 14-10-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 LH59_08680 f35509d2a9583e274f696d94a100af2e 226 SUPERFAMILY SSF75445 132 203 7.46E-22 T 14-10-2018 LH59_08680 f35509d2a9583e274f696d94a100af2e 226 SUPERFAMILY SSF100950 4 150 3.17E-40 T 14-10-2018 IPR037171 NagB/RpiA transferase-like LH59_08680 f35509d2a9583e274f696d94a100af2e 226 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 8 219 4.9E-61 T 14-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 LH59_08680 f35509d2a9583e274f696d94a100af2e 226 Gene3D G3DSA:3.40.50.1360 8 218 1.3E-69 T 14-10-2018 LH59_08680 f35509d2a9583e274f696d94a100af2e 226 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 54 218 1.1E-56 T 14-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 LH59_16840 8d26fe05df90306fa9c66d01c687f333 128 Gene3D G3DSA:2.60.40.790 1 127 1.7E-26 T 14-10-2018 IPR008978 HSP20-like chaperone LH59_16840 8d26fe05df90306fa9c66d01c687f333 128 Pfam PF00011 Hsp20/alpha crystallin family 27 125 1.2E-17 T 14-10-2018 IPR002068 Alpha crystallin/Hsp20 domain LH59_16840 8d26fe05df90306fa9c66d01c687f333 128 SUPERFAMILY SSF49764 17 126 4.88E-27 T 14-10-2018 IPR008978 HSP20-like chaperone LH59_24760 09673daad17ec953d16e7db9a333f88b 441 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 251 288 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LH59_24760 09673daad17ec953d16e7db9a333f88b 441 PIRSF PIRSF000521 21 440 7.3E-22 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LH59_24760 09673daad17ec953d16e7db9a333f88b 441 Gene3D G3DSA:3.90.1150.10 26 432 8.0E-139 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_24760 09673daad17ec953d16e7db9a333f88b 441 SUPERFAMILY SSF53383 1 440 3.59E-118 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_24760 09673daad17ec953d16e7db9a333f88b 441 Pfam PF00202 Aminotransferase class-III 28 437 8.4E-85 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LH59_24760 09673daad17ec953d16e7db9a333f88b 441 Gene3D G3DSA:3.40.640.10 62 343 8.0E-139 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_02735 96ab1526a4f35f31982e8fd4a0758739 311 Gene3D G3DSA:3.40.190.10 172 274 1.5E-40 T 14-10-2018 LH59_02735 96ab1526a4f35f31982e8fd4a0758739 311 Gene3D G3DSA:3.40.190.10 98 286 1.5E-40 T 14-10-2018 LH59_02735 96ab1526a4f35f31982e8fd4a0758739 311 SUPERFAMILY SSF53850 96 305 5.31E-35 T 14-10-2018 LH59_02735 96ab1526a4f35f31982e8fd4a0758739 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 8.2E-16 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_02735 96ab1526a4f35f31982e8fd4a0758739 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 5.3E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_02735 96ab1526a4f35f31982e8fd4a0758739 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 5.3E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_02735 96ab1526a4f35f31982e8fd4a0758739 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 5.3E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_02735 96ab1526a4f35f31982e8fd4a0758739 311 SUPERFAMILY SSF46785 5 110 6.53E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_02735 96ab1526a4f35f31982e8fd4a0758739 311 Pfam PF03466 LysR substrate binding domain 93 300 2.6E-33 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_02735 96ab1526a4f35f31982e8fd4a0758739 311 Gene3D G3DSA:1.10.10.10 6 94 8.1E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_01105 0fad119df46fd12b0b6ea42194104798 294 SUPERFAMILY SSF88659 199 292 7.29E-18 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like LH59_01105 0fad119df46fd12b0b6ea42194104798 294 Gene3D G3DSA:1.10.601.10 24 137 4.6E-31 T 14-10-2018 LH59_01105 0fad119df46fd12b0b6ea42194104798 294 Hamap MF_00961 RNA polymerase sigma factor RpoH [rpoH]. 9 294 51.701 T 14-10-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003700|GO:0006352|GO:0006355|GO:0016987 LH59_01105 0fad119df46fd12b0b6ea42194104798 294 Pfam PF04542 Sigma-70 region 2 65 134 9.6E-19 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 LH59_01105 0fad119df46fd12b0b6ea42194104798 294 TIGRFAM TIGR02392 rpoH_proteo: alternative sigma factor RpoH 27 293 8.3E-123 T 14-10-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003700|GO:0006352|GO:0006355|GO:0016987 LH59_01105 0fad119df46fd12b0b6ea42194104798 294 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 262 288 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 LH59_01105 0fad119df46fd12b0b6ea42194104798 294 Gene3D G3DSA:1.10.10.10 221 293 4.9E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_01105 0fad119df46fd12b0b6ea42194104798 294 SUPERFAMILY SSF88946 27 134 3.27E-39 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 LH59_01105 0fad119df46fd12b0b6ea42194104798 294 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 89 102 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 LH59_01105 0fad119df46fd12b0b6ea42194104798 294 PRINTS PR00046 Major sigma-70 factor signature 242 254 2.9E-19 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 LH59_01105 0fad119df46fd12b0b6ea42194104798 294 PRINTS PR00046 Major sigma-70 factor signature 89 102 2.9E-19 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 LH59_01105 0fad119df46fd12b0b6ea42194104798 294 PRINTS PR00046 Major sigma-70 factor signature 262 277 2.9E-19 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 LH59_01105 0fad119df46fd12b0b6ea42194104798 294 PRINTS PR00046 Major sigma-70 factor signature 277 288 2.9E-19 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 LH59_01105 0fad119df46fd12b0b6ea42194104798 294 Pfam PF04545 Sigma-70, region 4 238 289 5.1E-16 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 LH59_01105 0fad119df46fd12b0b6ea42194104798 294 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 61 290 2.2E-34 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 LH59_04660 5f682bbd2289b30cd7443ad26b90ed0e 254 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 56 249 1.6E-51 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 LH59_04660 5f682bbd2289b30cd7443ad26b90ed0e 254 Pfam PF10370 Domain of unknown function (DUF2437) 1 50 2.6E-12 T 14-10-2018 IPR018833 Domain of unknown function DUF2437 LH59_04660 5f682bbd2289b30cd7443ad26b90ed0e 254 SUPERFAMILY SSF56529 53 249 7.46E-59 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 LH59_04660 5f682bbd2289b30cd7443ad26b90ed0e 254 Gene3D G3DSA:3.90.850.10 53 251 7.8E-60 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 LH59_16360 7a33b40b842b87de467ac6cb6186338b 731 Pfam PF00593 TonB dependent receptor 292 730 4.6E-49 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_16360 7a33b40b842b87de467ac6cb6186338b 731 Pfam PF07715 TonB-dependent Receptor Plug Domain 80 179 9.8E-18 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_16360 7a33b40b842b87de467ac6cb6186338b 731 Gene3D G3DSA:2.170.130.10 57 189 2.9E-42 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily LH59_16360 7a33b40b842b87de467ac6cb6186338b 731 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 82 730 6.4E-111 T 14-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 LH59_16360 7a33b40b842b87de467ac6cb6186338b 731 Gene3D G3DSA:2.40.170.20 192 731 5.1E-180 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_16360 7a33b40b842b87de467ac6cb6186338b 731 SUPERFAMILY SSF56935 35 731 9.46E-124 T 14-10-2018 LH59_05995 fcbdd7bf0648ec24344178e892435591 1057 SUPERFAMILY SSF82866 312 507 2.09E-32 T 14-10-2018 LH59_05995 fcbdd7bf0648ec24344178e892435591 1057 Gene3D G3DSA:3.30.70.1430 576 674 2.8E-246 T 14-10-2018 LH59_05995 fcbdd7bf0648ec24344178e892435591 1057 Gene3D G3DSA:1.20.1640.10 32 524 2.8E-246 T 14-10-2018 LH59_05995 fcbdd7bf0648ec24344178e892435591 1057 SUPERFAMILY SSF82866 811 1034 1.15E-47 T 14-10-2018 LH59_05995 fcbdd7bf0648ec24344178e892435591 1057 Gene3D G3DSA:3.30.2090.10 727 814 2.8E-246 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_05995 fcbdd7bf0648ec24344178e892435591 1057 Gene3D G3DSA:3.30.70.1430 59 822 2.8E-246 T 14-10-2018 LH59_05995 fcbdd7bf0648ec24344178e892435591 1057 SUPERFAMILY SSF82693 575 670 1.88E-5 T 14-10-2018 LH59_05995 fcbdd7bf0648ec24344178e892435591 1057 Gene3D G3DSA:3.30.2090.10 198 287 2.8E-246 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_05995 fcbdd7bf0648ec24344178e892435591 1057 Gene3D G3DSA:3.30.70.1440 675 874 2.8E-246 T 14-10-2018 LH59_05995 fcbdd7bf0648ec24344178e892435591 1057 PRINTS PR00702 Acriflavin resistance protein family signature 456 479 1.7E-21 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_05995 fcbdd7bf0648ec24344178e892435591 1057 PRINTS PR00702 Acriflavin resistance protein family signature 403 427 1.7E-21 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_05995 fcbdd7bf0648ec24344178e892435591 1057 PRINTS PR00702 Acriflavin resistance protein family signature 481 504 1.7E-21 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_05995 fcbdd7bf0648ec24344178e892435591 1057 PRINTS PR00702 Acriflavin resistance protein family signature 561 578 1.7E-21 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_05995 fcbdd7bf0648ec24344178e892435591 1057 PRINTS PR00702 Acriflavin resistance protein family signature 57 75 1.7E-21 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_05995 fcbdd7bf0648ec24344178e892435591 1057 PRINTS PR00702 Acriflavin resistance protein family signature 349 372 1.7E-21 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_05995 fcbdd7bf0648ec24344178e892435591 1057 SUPERFAMILY SSF82693 59 154 5.41E-17 T 14-10-2018 LH59_05995 fcbdd7bf0648ec24344178e892435591 1057 Pfam PF00873 AcrB/AcrD/AcrF family 25 1027 3.5E-163 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_05995 fcbdd7bf0648ec24344178e892435591 1057 SUPERFAMILY SSF82714 729 813 1.31E-12 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_05995 fcbdd7bf0648ec24344178e892435591 1057 SUPERFAMILY SSF82714 204 284 7.06E-13 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_05995 fcbdd7bf0648ec24344178e892435591 1057 Gene3D G3DSA:1.20.1640.10 525 1026 2.8E-246 T 14-10-2018 LH59_05995 fcbdd7bf0648ec24344178e892435591 1057 Gene3D G3DSA:3.30.70.1320 155 345 2.8E-246 T 14-10-2018 LH59_05995 fcbdd7bf0648ec24344178e892435591 1057 SUPERFAMILY SSF82693 155 337 4.18E-18 T 14-10-2018 LH59_04405 a77175b6c1d9a3756cd0ac934666f19e 177 Pfam PF01327 Polypeptide deformylase 3 158 1.4E-48 T 14-10-2018 IPR023635 Peptide deformylase LH59_04405 a77175b6c1d9a3756cd0ac934666f19e 177 SUPERFAMILY SSF56420 1 165 2.49E-58 T 14-10-2018 IPR036821 Peptide deformylase superfamily LH59_04405 a77175b6c1d9a3756cd0ac934666f19e 177 Gene3D G3DSA:3.90.45.10 1 177 1.4E-67 T 14-10-2018 IPR036821 Peptide deformylase superfamily LH59_04405 a77175b6c1d9a3756cd0ac934666f19e 177 PIRSF PIRSF004749 1 168 3.4E-48 T 14-10-2018 IPR023635 Peptide deformylase LH59_04405 a77175b6c1d9a3756cd0ac934666f19e 177 PRINTS PR01576 Peptide deformylase signature 97 108 4.2E-30 T 14-10-2018 IPR023635 Peptide deformylase LH59_04405 a77175b6c1d9a3756cd0ac934666f19e 177 PRINTS PR01576 Peptide deformylase signature 128 157 4.2E-30 T 14-10-2018 IPR023635 Peptide deformylase LH59_04405 a77175b6c1d9a3756cd0ac934666f19e 177 PRINTS PR01576 Peptide deformylase signature 33 62 4.2E-30 T 14-10-2018 IPR023635 Peptide deformylase LH59_04405 a77175b6c1d9a3756cd0ac934666f19e 177 PRINTS PR01576 Peptide deformylase signature 109 127 4.2E-30 T 14-10-2018 IPR023635 Peptide deformylase LH59_04405 a77175b6c1d9a3756cd0ac934666f19e 177 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 4 159 2.0E-36 T 14-10-2018 IPR023635 Peptide deformylase LH59_04405 a77175b6c1d9a3756cd0ac934666f19e 177 Hamap MF_00163 Peptide deformylase [def]. 1 166 26.809 T 14-10-2018 IPR023635 Peptide deformylase LH59_17220 2c78488f5aba6425311c01e0d1a9890f 816 Gene3D G3DSA:1.10.8.60 493 596 3.6E-30 T 14-10-2018 LH59_17220 2c78488f5aba6425311c01e0d1a9890f 816 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 582 784 4.3E-95 T 14-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 LH59_17220 2c78488f5aba6425311c01e0d1a9890f 816 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 354 491 7.5E-18 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 LH59_17220 2c78488f5aba6425311c01e0d1a9890f 816 Gene3D G3DSA:3.30.230.10 597 784 7.0E-81 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup LH59_17220 2c78488f5aba6425311c01e0d1a9890f 816 Gene3D G3DSA:1.20.58.1480 124 248 1.7E-42 T 14-10-2018 LH59_17220 2c78488f5aba6425311c01e0d1a9890f 816 PIRSF PIRSF001174 2 787 0.0 T 14-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 LH59_17220 2c78488f5aba6425311c01e0d1a9890f 816 SUPERFAMILY SSF88697 13 204 1.86E-53 T 14-10-2018 IPR015947 PUA-like superfamily LH59_17220 2c78488f5aba6425311c01e0d1a9890f 816 SMART SM00382 350 494 2.5E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_17220 2c78488f5aba6425311c01e0d1a9890f 816 Gene3D G3DSA:3.40.50.300 316 492 2.7E-63 T 14-10-2018 LH59_17220 2c78488f5aba6425311c01e0d1a9890f 816 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 685 704 3.5E-56 T 14-10-2018 LH59_17220 2c78488f5aba6425311c01e0d1a9890f 816 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 738 756 3.5E-56 T 14-10-2018 LH59_17220 2c78488f5aba6425311c01e0d1a9890f 816 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 715 734 3.5E-56 T 14-10-2018 LH59_17220 2c78488f5aba6425311c01e0d1a9890f 816 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 358 377 3.5E-56 T 14-10-2018 LH59_17220 2c78488f5aba6425311c01e0d1a9890f 816 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 607 623 3.5E-56 T 14-10-2018 LH59_17220 2c78488f5aba6425311c01e0d1a9890f 816 Gene3D G3DSA:2.30.130.40 3 121 1.8E-36 T 14-10-2018 LH59_17220 2c78488f5aba6425311c01e0d1a9890f 816 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 14 203 1.7E-41 T 14-10-2018 IPR003111 Lon, substrate-binding domain LH59_17220 2c78488f5aba6425311c01e0d1a9890f 816 TIGRFAM TIGR00763 lon: endopeptidase La 15 783 2.2E-301 T 14-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 LH59_17220 2c78488f5aba6425311c01e0d1a9890f 816 SUPERFAMILY SSF54211 607 782 6.83E-57 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold LH59_17220 2c78488f5aba6425311c01e0d1a9890f 816 SUPERFAMILY SSF52540 317 597 8.09E-51 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_17220 2c78488f5aba6425311c01e0d1a9890f 816 SMART SM00464 13 205 7.5E-76 T 14-10-2018 IPR003111 Lon, substrate-binding domain LH59_17220 2c78488f5aba6425311c01e0d1a9890f 816 Hamap MF_01973 Lon protease [lon]. 14 784 70.361 T 14-10-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 LH59_17220 2c78488f5aba6425311c01e0d1a9890f 816 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 688 696 - T 14-10-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 LH59_22975 9593dcc576b005f62c236e2a6f7b96b7 141 Gene3D G3DSA:3.40.50.620 1 141 3.2E-27 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LH59_22975 9593dcc576b005f62c236e2a6f7b96b7 141 Pfam PF00582 Universal stress protein family 1 141 2.8E-21 T 14-10-2018 IPR006016 UspA LH59_22975 9593dcc576b005f62c236e2a6f7b96b7 141 SUPERFAMILY SSF52402 1 141 1.17E-26 T 14-10-2018 LH59_22975 9593dcc576b005f62c236e2a6f7b96b7 141 PRINTS PR01438 Universal stress protein signature 1 18 2.4E-15 T 14-10-2018 IPR006015 Universal stress protein A LH59_22975 9593dcc576b005f62c236e2a6f7b96b7 141 PRINTS PR01438 Universal stress protein signature 119 141 2.4E-15 T 14-10-2018 IPR006015 Universal stress protein A LH59_22975 9593dcc576b005f62c236e2a6f7b96b7 141 PRINTS PR01438 Universal stress protein signature 101 113 2.4E-15 T 14-10-2018 IPR006015 Universal stress protein A LH59_12780 f852de9f4f769fc108253c3a51f4b166 556 SUPERFAMILY SSF161098 290 549 2.18E-38 T 14-10-2018 IPR035906 MetI-like superfamily LH59_12780 f852de9f4f769fc108253c3a51f4b166 556 Gene3D G3DSA:1.10.3720.10 22 280 6.4E-50 T 14-10-2018 IPR035906 MetI-like superfamily LH59_12780 f852de9f4f769fc108253c3a51f4b166 556 Gene3D G3DSA:1.10.3720.10 293 554 5.7E-33 T 14-10-2018 IPR035906 MetI-like superfamily LH59_12780 f852de9f4f769fc108253c3a51f4b166 556 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 277 7.6E-14 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_12780 f852de9f4f769fc108253c3a51f4b166 556 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 382 545 1.5E-8 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_12780 f852de9f4f769fc108253c3a51f4b166 556 SUPERFAMILY SSF161098 20 271 2.75E-41 T 14-10-2018 IPR035906 MetI-like superfamily LH59_02935 21d35c4f2ead97ccb752a38795fceade 783 Gene3D G3DSA:3.20.20.70 412 764 1.4E-115 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_02935 21d35c4f2ead97ccb752a38795fceade 783 Gene3D G3DSA:3.30.9.20 40 256 3.5E-125 T 14-10-2018 LH59_02935 21d35c4f2ead97ccb752a38795fceade 783 SUPERFAMILY SSF51395 412 764 8.18E-116 T 14-10-2018 LH59_02935 21d35c4f2ead97ccb752a38795fceade 783 SUPERFAMILY SSF51905 1 358 7.22E-37 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_02935 21d35c4f2ead97ccb752a38795fceade 783 Gene3D G3DSA:3.50.50.60 3 353 3.5E-125 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_02935 21d35c4f2ead97ccb752a38795fceade 783 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 1.4E-8 T 14-10-2018 LH59_02935 21d35c4f2ead97ccb752a38795fceade 783 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 279 294 1.4E-8 T 14-10-2018 LH59_02935 21d35c4f2ead97ccb752a38795fceade 783 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 294 310 1.4E-8 T 14-10-2018 LH59_02935 21d35c4f2ead97ccb752a38795fceade 783 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 131 146 1.4E-8 T 14-10-2018 LH59_02935 21d35c4f2ead97ccb752a38795fceade 783 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 415 744 6.6E-63 T 14-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 LH59_20370 5cad475dde35662715e94954e148d201 437 TIGRFAM TIGR04247 NosD_copper_fam: nitrous oxide reductase family maturation protein NosD 47 423 2.2E-146 T 14-10-2018 IPR026464 Nitrous oxide reductase family maturation protein NosD LH59_20370 5cad475dde35662715e94954e148d201 437 SMART SM00710 228 249 3100.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat LH59_20370 5cad475dde35662715e94954e148d201 437 SMART SM00710 273 294 110.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat LH59_20370 5cad475dde35662715e94954e148d201 437 SMART SM00710 206 227 110.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat LH59_20370 5cad475dde35662715e94954e148d201 437 SMART SM00710 154 183 2300.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat LH59_20370 5cad475dde35662715e94954e148d201 437 SMART SM00710 184 205 23.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat LH59_20370 5cad475dde35662715e94954e148d201 437 SMART SM00710 318 371 4900.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat LH59_20370 5cad475dde35662715e94954e148d201 437 SMART SM00710 295 316 620.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat LH59_20370 5cad475dde35662715e94954e148d201 437 SMART SM00710 132 153 13.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat LH59_20370 5cad475dde35662715e94954e148d201 437 SMART SM00710 102 130 560.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat LH59_20370 5cad475dde35662715e94954e148d201 437 SMART SM00710 250 272 1300.0 T 14-10-2018 IPR006626 Parallel beta-helix repeat LH59_20370 5cad475dde35662715e94954e148d201 437 SMART SM00722 210 370 2.9E-19 T 14-10-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain LH59_20370 5cad475dde35662715e94954e148d201 437 SMART SM00722 54 204 3.7E-10 T 14-10-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain LH59_20370 5cad475dde35662715e94954e148d201 437 Pfam PF05048 Periplasmic copper-binding protein (NosD) 162 386 3.5E-58 T 14-10-2018 IPR007742 Periplasmic copper-binding protein NosD, beta helix domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 LH59_20370 5cad475dde35662715e94954e148d201 437 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 178 216 7.6E-5 T 14-10-2018 IPR022441 Parallel beta-helix repeat-2 Reactome: R-HSA-8951664|Reactome: R-HSA-983168 LH59_20370 5cad475dde35662715e94954e148d201 437 Gene3D G3DSA:2.160.20.10 40 389 1.8E-29 T 14-10-2018 IPR012334 Pectin lyase fold LH59_20370 5cad475dde35662715e94954e148d201 437 SUPERFAMILY SSF51126 41 412 2.2E-79 T 14-10-2018 IPR011050 Pectin lyase fold/virulence factor LH59_25870 f17e02e85979c218729a00f1ee62f533 293 Gene3D G3DSA:3.40.190.10 164 264 4.5E-65 T 14-10-2018 LH59_25870 f17e02e85979c218729a00f1ee62f533 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 6.3E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_25870 f17e02e85979c218729a00f1ee62f533 293 Gene3D G3DSA:3.40.190.10 93 289 4.5E-65 T 14-10-2018 LH59_25870 f17e02e85979c218729a00f1ee62f533 293 Gene3D G3DSA:1.10.10.10 1 87 1.4E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_25870 f17e02e85979c218729a00f1ee62f533 293 SUPERFAMILY SSF53850 89 292 1.12E-40 T 14-10-2018 LH59_25870 f17e02e85979c218729a00f1ee62f533 293 Pfam PF03466 LysR substrate binding domain 89 292 5.0E-43 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_25870 f17e02e85979c218729a00f1ee62f533 293 SUPERFAMILY SSF46785 2 113 1.96E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_15590 b4a976972a92894663a34c1f58a0ffb9 175 Gene3D G3DSA:2.60.40.200 21 175 3.6E-49 T 14-10-2018 IPR036423 Superoxide dismutase-like, copper/zinc binding domain superfamily GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 LH59_15590 b4a976972a92894663a34c1f58a0ffb9 175 SUPERFAMILY SSF49329 36 175 1.83E-46 T 14-10-2018 IPR036423 Superoxide dismutase-like, copper/zinc binding domain superfamily GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 LH59_15590 b4a976972a92894663a34c1f58a0ffb9 175 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 34 174 4.4E-34 T 14-10-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 LH59_15590 b4a976972a92894663a34c1f58a0ffb9 175 ProSitePatterns PS00087 Copper/Zinc superoxide dismutase signature 1. 67 77 - T 14-10-2018 IPR018152 Superoxide dismutase, copper/zinc, binding site GO:0004784|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 LH59_21985 6228cbea5eaeae73e38a56740286a5e5 257 Pfam PF00106 short chain dehydrogenase 4 189 2.7E-44 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_21985 6228cbea5eaeae73e38a56740286a5e5 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 1.7E-28 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_21985 6228cbea5eaeae73e38a56740286a5e5 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 1.7E-28 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_21985 6228cbea5eaeae73e38a56740286a5e5 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 1.7E-28 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_21985 6228cbea5eaeae73e38a56740286a5e5 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 1.7E-28 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_21985 6228cbea5eaeae73e38a56740286a5e5 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.7E-28 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_21985 6228cbea5eaeae73e38a56740286a5e5 257 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LH59_21985 6228cbea5eaeae73e38a56740286a5e5 257 Gene3D G3DSA:3.40.50.720 2 250 6.9E-58 T 14-10-2018 LH59_21985 6228cbea5eaeae73e38a56740286a5e5 257 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 180 0.0012 T 14-10-2018 LH59_21985 6228cbea5eaeae73e38a56740286a5e5 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 2.0E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_21985 6228cbea5eaeae73e38a56740286a5e5 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 2.0E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_21985 6228cbea5eaeae73e38a56740286a5e5 257 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 2.0E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_21985 6228cbea5eaeae73e38a56740286a5e5 257 SUPERFAMILY SSF51735 3 246 1.81E-61 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_01860 dafc7cf3b03083f2adf27c784b40a405 267 Gene3D G3DSA:3.40.30.10 114 267 3.0E-33 T 14-10-2018 LH59_01860 dafc7cf3b03083f2adf27c784b40a405 267 SUPERFAMILY SSF52833 118 267 1.24E-31 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_01860 dafc7cf3b03083f2adf27c784b40a405 267 Pfam PF13098 Thioredoxin-like domain 146 266 1.6E-27 T 14-10-2018 IPR012336 Thioredoxin-like fold LH59_01860 dafc7cf3b03083f2adf27c784b40a405 267 Pfam PF10411 Disulfide bond isomerase protein N-terminus 65 117 3.7E-11 T 14-10-2018 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal LH59_01860 dafc7cf3b03083f2adf27c784b40a405 267 ProSitePatterns PS00194 Thioredoxin family active site. 153 171 - T 14-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 LH59_27580 4b9a20ce06cd26d7e83617163e0d0063 205 Gene3D G3DSA:1.10.10.60 2 50 8.7E-13 T 14-10-2018 LH59_27580 4b9a20ce06cd26d7e83617163e0d0063 205 Gene3D G3DSA:1.10.357.10 52 197 2.1E-35 T 14-10-2018 LH59_27580 4b9a20ce06cd26d7e83617163e0d0063 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 1.8E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_27580 4b9a20ce06cd26d7e83617163e0d0063 205 SUPERFAMILY SSF46689 5 73 1.03E-12 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_27580 4b9a20ce06cd26d7e83617163e0d0063 205 SUPERFAMILY SSF48498 81 195 8.06E-28 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily LH59_22060 ff87190d029e84427b05df0d5860a83f 108 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 3 104 6.0E-33 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family LH59_22060 ff87190d029e84427b05df0d5860a83f 108 Pfam PF02575 YbaB/EbfC DNA-binding family 10 98 1.0E-35 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family LH59_22060 ff87190d029e84427b05df0d5860a83f 108 PIRSF PIRSF004555 2 108 7.9E-39 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family LH59_22060 ff87190d029e84427b05df0d5860a83f 108 SUPERFAMILY SSF82607 10 102 2.22E-35 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily LH59_22060 ff87190d029e84427b05df0d5860a83f 108 Gene3D G3DSA:3.30.1310.10 1 108 2.9E-45 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily LH59_22060 ff87190d029e84427b05df0d5860a83f 108 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 4 97 22.819 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family LH59_10830 6b4321f5b6e48a6b494558f779cb4ca9 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 15 71 3.2E-15 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_10830 6b4321f5b6e48a6b494558f779cb4ca9 314 Gene3D G3DSA:3.40.190.10 171 271 1.1E-66 T 14-10-2018 LH59_10830 6b4321f5b6e48a6b494558f779cb4ca9 314 Pfam PF03466 LysR substrate binding domain 96 300 4.9E-42 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_10830 6b4321f5b6e48a6b494558f779cb4ca9 314 Gene3D G3DSA:1.10.10.10 11 94 7.5E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_10830 6b4321f5b6e48a6b494558f779cb4ca9 314 Gene3D G3DSA:3.40.190.10 99 295 1.1E-66 T 14-10-2018 LH59_10830 6b4321f5b6e48a6b494558f779cb4ca9 314 SUPERFAMILY SSF53850 98 302 1.99E-44 T 14-10-2018 LH59_10830 6b4321f5b6e48a6b494558f779cb4ca9 314 SUPERFAMILY SSF46785 11 120 3.37E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_24600 faa0cbca04e984d1c941db559ae9a84c 439 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 137 434 1.2E-52 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 LH59_24600 faa0cbca04e984d1c941db559ae9a84c 439 TIGRFAM TIGR01266 fum_ac_acetase: fumarylacetoacetase 15 437 6.4E-159 T 14-10-2018 IPR005959 Fumarylacetoacetase GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 LH59_24600 faa0cbca04e984d1c941db559ae9a84c 439 SUPERFAMILY SSF56529 133 437 4.84E-90 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 LH59_24600 faa0cbca04e984d1c941db559ae9a84c 439 Pfam PF09298 Fumarylacetoacetase N-terminal 30 131 4.8E-22 T 14-10-2018 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 LH59_24600 faa0cbca04e984d1c941db559ae9a84c 439 Gene3D G3DSA:2.30.30.230 1 128 1.3E-33 T 14-10-2018 IPR036462 Fumarylacetoacetase, N-terminal domain superfamily GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 LH59_24600 faa0cbca04e984d1c941db559ae9a84c 439 Gene3D G3DSA:3.90.850.10 130 439 9.5E-113 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 LH59_24600 faa0cbca04e984d1c941db559ae9a84c 439 SUPERFAMILY SSF63433 14 131 2.09E-30 T 14-10-2018 IPR036462 Fumarylacetoacetase, N-terminal domain superfamily GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 LH59_15685 812d03882bd46910d07365cfb213c5b3 509 SUPERFAMILY SSF103473 11 497 4.97E-59 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_15685 812d03882bd46910d07365cfb213c5b3 509 Pfam PF07690 Major Facilitator Superfamily 26 415 3.2E-45 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_15685 812d03882bd46910d07365cfb213c5b3 509 PRINTS PR01036 Tetracycline resistance protein TetB signature 406 425 4.8E-6 T 14-10-2018 LH59_15685 812d03882bd46910d07365cfb213c5b3 509 PRINTS PR01036 Tetracycline resistance protein TetB signature 83 105 4.8E-6 T 14-10-2018 LH59_15685 812d03882bd46910d07365cfb213c5b3 509 PRINTS PR01036 Tetracycline resistance protein TetB signature 145 169 4.8E-6 T 14-10-2018 LH59_15685 812d03882bd46910d07365cfb213c5b3 509 PRINTS PR01036 Tetracycline resistance protein TetB signature 309 333 4.8E-6 T 14-10-2018 LH59_15685 812d03882bd46910d07365cfb213c5b3 509 Gene3D G3DSA:1.20.1250.20 275 497 1.2E-17 T 14-10-2018 LH59_15685 812d03882bd46910d07365cfb213c5b3 509 Gene3D G3DSA:1.20.1720.10 20 228 1.9E-39 T 14-10-2018 LH59_24065 bedd61421bc28a7d521816c63f6ad851 221 SUPERFAMILY SSF56300 34 166 2.32E-13 T 14-10-2018 LH59_24065 bedd61421bc28a7d521816c63f6ad851 221 TIGRFAM TIGR04123 P_estr_lig_assc: metallophosphoesterase, DNA ligase-associated 13 210 2.9E-54 T 14-10-2018 IPR026336 Metallophosphoesterase, DNA ligase-associated LH59_24065 bedd61421bc28a7d521816c63f6ad851 221 Pfam PF00149 Calcineurin-like phosphoesterase 34 128 2.8E-6 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 LH59_24065 bedd61421bc28a7d521816c63f6ad851 221 Gene3D G3DSA:3.60.21.10 33 172 3.3E-9 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like LH59_24065 bedd61421bc28a7d521816c63f6ad851 221 PIRSF PIRSF000887 11 205 5.4E-39 T 14-10-2018 IPR024173 Phosphoesterase, MJ0037 LH59_02585 1adf7bbcc8f12054fa74db765a1cb6f9 403 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 16 110 3.2E-31 T 14-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain LH59_02585 1adf7bbcc8f12054fa74db765a1cb6f9 403 SUPERFAMILY SSF54826 1 112 1.4E-33 T 14-10-2018 LH59_02585 1adf7bbcc8f12054fa74db765a1cb6f9 403 SMART SM00922 128 257 2.2E-16 T 14-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal LH59_02585 1adf7bbcc8f12054fa74db765a1cb6f9 403 Gene3D G3DSA:3.20.20.120 105 366 2.3E-172 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily LH59_02585 1adf7bbcc8f12054fa74db765a1cb6f9 403 Gene3D G3DSA:3.30.390.10 5 399 2.3E-172 T 14-10-2018 IPR029017 Enolase-like, N-terminal LH59_02585 1adf7bbcc8f12054fa74db765a1cb6f9 403 SUPERFAMILY SSF51604 98 386 1.7E-75 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily LH59_02585 1adf7bbcc8f12054fa74db765a1cb6f9 403 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 85 110 - T 14-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 LH59_02585 1adf7bbcc8f12054fa74db765a1cb6f9 403 Pfam PF13378 Enolase C-terminal domain-like 135 377 2.7E-38 T 14-10-2018 IPR029065 Enolase C-terminal domain-like LH59_21300 0affb0414326bb1abdbc0f94e9fb1eed 264 Pfam PF00005 ABC transporter 22 177 7.1E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_21300 0affb0414326bb1abdbc0f94e9fb1eed 264 SUPERFAMILY SSF52540 2 235 6.5E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_21300 0affb0414326bb1abdbc0f94e9fb1eed 264 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_21300 0affb0414326bb1abdbc0f94e9fb1eed 264 Gene3D G3DSA:3.40.50.300 1 254 3.8E-57 T 14-10-2018 LH59_21300 0affb0414326bb1abdbc0f94e9fb1eed 264 SMART SM00382 31 226 3.6E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_22970 6e6ab094bcf3f90455ce94ac7095d28b 261 SUPERFAMILY SSF53681 104 253 1.46E-29 T 14-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 LH59_22970 6e6ab094bcf3f90455ce94ac7095d28b 261 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 175 185 - T 14-10-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 LH59_22970 6e6ab094bcf3f90455ce94ac7095d28b 261 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 65 73 - T 14-10-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 LH59_22970 6e6ab094bcf3f90455ce94ac7095d28b 261 SUPERFAMILY SSF53681 1 102 2.88E-30 T 14-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 LH59_22970 6e6ab094bcf3f90455ce94ac7095d28b 261 TIGRFAM TIGR00067 glut_race: glutamate racemase 1 244 6.0E-57 T 14-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 LH59_22970 6e6ab094bcf3f90455ce94ac7095d28b 261 Hamap MF_00258 Glutamate racemase [murI]. 1 250 31.54 T 14-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 LH59_22970 6e6ab094bcf3f90455ce94ac7095d28b 261 Gene3D G3DSA:3.40.50.1860 1 248 5.6E-77 T 14-10-2018 LH59_22970 6e6ab094bcf3f90455ce94ac7095d28b 261 Pfam PF01177 Asp/Glu/Hydantoin racemase 1 209 1.8E-31 T 14-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 LH59_22970 6e6ab094bcf3f90455ce94ac7095d28b 261 Gene3D G3DSA:3.40.50.1860 91 202 5.6E-77 T 14-10-2018 LH59_22760 6973ca3aeab02b115d8050c8387b7e2f 225 SUPERFAMILY SSF54593 3 112 1.52E-5 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_22760 6973ca3aeab02b115d8050c8387b7e2f 225 Gene3D G3DSA:3.10.180.10 2 161 2.0E-6 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_22760 6973ca3aeab02b115d8050c8387b7e2f 225 Pfam PF13468 Glyoxalase-like domain 5 193 2.2E-39 T 14-10-2018 IPR025870 Glyoxalase-like domain LH59_07685 92e0b7b2d99d999bf260f462a3a8638d 905 Gene3D G3DSA:1.10.150.20 686 829 6.5E-106 T 14-10-2018 LH59_07685 92e0b7b2d99d999bf260f462a3a8638d 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 707 720 8.6E-67 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LH59_07685 92e0b7b2d99d999bf260f462a3a8638d 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 731 756 8.6E-67 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LH59_07685 92e0b7b2d99d999bf260f462a3a8638d 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 677 700 8.6E-67 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LH59_07685 92e0b7b2d99d999bf260f462a3a8638d 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 768 779 8.6E-67 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LH59_07685 92e0b7b2d99d999bf260f462a3a8638d 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 790 801 8.6E-67 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LH59_07685 92e0b7b2d99d999bf260f462a3a8638d 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 633 655 8.6E-67 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LH59_07685 92e0b7b2d99d999bf260f462a3a8638d 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 822 838 8.6E-67 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LH59_07685 92e0b7b2d99d999bf260f462a3a8638d 905 PRINTS PR00868 DNA-polymerase family A (pol I) signature 852 865 8.6E-67 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LH59_07685 92e0b7b2d99d999bf260f462a3a8638d 905 SUPERFAMILY SSF56672 507 905 4.0E-150 T 14-10-2018 LH59_07685 92e0b7b2d99d999bf260f462a3a8638d 905 SMART SM00479 330 497 0.0095 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III LH59_07685 92e0b7b2d99d999bf260f462a3a8638d 905 Pfam PF01612 3'-5' exonuclease 310 495 1.8E-36 T 14-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 LH59_07685 92e0b7b2d99d999bf260f462a3a8638d 905 ProSitePatterns PS00447 DNA polymerase family A signature. 731 750 - T 14-10-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LH59_07685 92e0b7b2d99d999bf260f462a3a8638d 905 Gene3D G3DSA:1.10.150.20 170 242 1.6E-88 T 14-10-2018 LH59_07685 92e0b7b2d99d999bf260f462a3a8638d 905 TIGRFAM TIGR00593 pola: DNA polymerase I 5 905 2.0E-271 T 14-10-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LH59_07685 92e0b7b2d99d999bf260f462a3a8638d 905 Pfam PF00476 DNA polymerase family A 529 902 6.7E-152 T 14-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LH59_07685 92e0b7b2d99d999bf260f462a3a8638d 905 Gene3D G3DSA:1.20.1060.10 521 636 2.7E-43 T 14-10-2018 LH59_07685 92e0b7b2d99d999bf260f462a3a8638d 905 Gene3D G3DSA:3.30.70.370 644 901 6.5E-106 T 14-10-2018 LH59_07685 92e0b7b2d99d999bf260f462a3a8638d 905 SMART SM00474 310 496 2.6E-25 T 14-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 LH59_07685 92e0b7b2d99d999bf260f462a3a8638d 905 SMART SM00475 2 259 1.7E-114 T 14-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 LH59_07685 92e0b7b2d99d999bf260f462a3a8638d 905 SUPERFAMILY SSF53098 309 495 6.7E-50 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily LH59_07685 92e0b7b2d99d999bf260f462a3a8638d 905 Gene3D G3DSA:3.40.50.1010 5 276 1.6E-88 T 14-10-2018 LH59_07685 92e0b7b2d99d999bf260f462a3a8638d 905 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 167 253 1.9E-22 T 14-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 LH59_07685 92e0b7b2d99d999bf260f462a3a8638d 905 SUPERFAMILY SSF88723 1 166 2.8E-56 T 14-10-2018 IPR029060 PIN-like domain superfamily LH59_07685 92e0b7b2d99d999bf260f462a3a8638d 905 SMART SM00482 664 869 1.9E-106 T 14-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LH59_07685 92e0b7b2d99d999bf260f462a3a8638d 905 SMART SM00279 169 204 5.9E-12 T 14-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 LH59_07685 92e0b7b2d99d999bf260f462a3a8638d 905 SUPERFAMILY SSF47807 167 283 1.18E-29 T 14-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily LH59_07685 92e0b7b2d99d999bf260f462a3a8638d 905 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 5 166 4.2E-54 T 14-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 LH59_07685 92e0b7b2d99d999bf260f462a3a8638d 905 Gene3D G3DSA:3.30.420.10 308 520 3.4E-60 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 LH59_27015 09ae0435605ad367b4a333fa3527e378 708 SUPERFAMILY SSF53955 538 695 1.8E-43 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily LH59_27015 09ae0435605ad367b4a333fa3527e378 708 Gene3D G3DSA:1.25.20.10 92 442 5.8E-56 T 14-10-2018 LH59_27015 09ae0435605ad367b4a333fa3527e378 708 Pfam PF01464 Transglycosylase SLT domain 541 646 5.2E-21 T 14-10-2018 IPR008258 Transglycosylase SLT domain 1 LH59_27015 09ae0435605ad367b4a333fa3527e378 708 Pfam PF14718 Soluble lytic murein transglycosylase L domain 462 521 9.0E-9 T 14-10-2018 IPR012289 Lytic transglycosylase, superhelical linker GO:0004553|GO:0042597 LH59_27015 09ae0435605ad367b4a333fa3527e378 708 Gene3D G3DSA:1.10.530.10 529 694 1.1E-39 T 14-10-2018 LH59_27015 09ae0435605ad367b4a333fa3527e378 708 SUPERFAMILY SSF48435 90 531 1.24E-101 T 14-10-2018 IPR008939 Lytic transglycosylase, superhelical U-shaped GO:0004553|GO:0042597 LH59_10010 0ebafdba8c757824fc81dd19b7e9e3eb 564 Gene3D G3DSA:3.30.300.30 337 443 1.0E-10 T 14-10-2018 LH59_10010 0ebafdba8c757824fc81dd19b7e9e3eb 564 Gene3D G3DSA:3.10.129.10 455 561 6.9E-31 T 14-10-2018 LH59_10010 0ebafdba8c757824fc81dd19b7e9e3eb 564 SUPERFAMILY SSF54637 458 556 2.67E-14 T 14-10-2018 IPR029069 HotDog domain superfamily LH59_10010 0ebafdba8c757824fc81dd19b7e9e3eb 564 Gene3D G3DSA:3.40.50.12780 11 311 6.3E-29 T 14-10-2018 LH59_10010 0ebafdba8c757824fc81dd19b7e9e3eb 564 ProSitePatterns PS00455 Putative AMP-binding domain signature. 132 143 - T 14-10-2018 IPR020845 AMP-binding, conserved site LH59_10010 0ebafdba8c757824fc81dd19b7e9e3eb 564 Pfam PF00501 AMP-binding enzyme 131 282 2.7E-12 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 LH59_10010 0ebafdba8c757824fc81dd19b7e9e3eb 564 SUPERFAMILY SSF56801 19 434 1.31E-48 T 14-10-2018 LH59_19075 cf914c740836e4af63f99e4624c37965 413 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 215 376 1.3E-35 T 14-10-2018 IPR000160 GGDEF domain LH59_19075 cf914c740836e4af63f99e4624c37965 413 SMART SM00267 206 378 1.4E-42 T 14-10-2018 IPR000160 GGDEF domain LH59_19075 cf914c740836e4af63f99e4624c37965 413 SUPERFAMILY SSF55073 222 376 1.18E-37 T 14-10-2018 IPR029787 Nucleotide cyclase LH59_19075 cf914c740836e4af63f99e4624c37965 413 Pfam PF00990 Diguanylate cyclase, GGDEF domain 217 373 2.9E-36 T 14-10-2018 IPR000160 GGDEF domain LH59_19075 cf914c740836e4af63f99e4624c37965 413 Gene3D G3DSA:3.30.70.270 206 377 3.4E-45 T 14-10-2018 LH59_05005 3441cc8be04f7145ee810a3b329cf763 357 Gene3D G3DSA:3.40.50.300 34 195 5.1E-41 T 14-10-2018 LH59_05005 3441cc8be04f7145ee810a3b329cf763 357 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 23 249 6.9E-117 T 14-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 LH59_05005 3441cc8be04f7145ee810a3b329cf763 357 SUPERFAMILY SSF52540 34 264 5.5E-53 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_05005 3441cc8be04f7145ee810a3b329cf763 357 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 267 340 3.8E-33 T 14-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 LH59_05005 3441cc8be04f7145ee810a3b329cf763 357 SMART SM00382 65 193 2.1E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_05005 3441cc8be04f7145ee810a3b329cf763 357 SUPERFAMILY SSF46785 271 344 4.67E-26 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_05005 3441cc8be04f7145ee810a3b329cf763 357 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 357 180.014 T 14-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 LH59_05005 3441cc8be04f7145ee810a3b329cf763 357 Gene3D G3DSA:1.10.8.60 196 269 6.9E-28 T 14-10-2018 LH59_05005 3441cc8be04f7145ee810a3b329cf763 357 Gene3D G3DSA:1.10.10.10 271 350 2.0E-33 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_05005 3441cc8be04f7145ee810a3b329cf763 357 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 37 340 1.1E-144 T 14-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 LH59_05005 3441cc8be04f7145ee810a3b329cf763 357 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 264 342 6.0E-39 T 14-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 LH59_07405 7defa38bcf042189a274d296a6f22fab 299 TIGRFAM TIGR00969 3a0106s02: sulfate ABC transporter, permease protein 19 273 7.3E-101 T 14-10-2018 IPR005667 Sulphate ABC transporter permease protein 2 GO:0008272|GO:0015419|GO:0016020 LH59_07405 7defa38bcf042189a274d296a6f22fab 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 266 4.3E-18 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_07405 7defa38bcf042189a274d296a6f22fab 299 SUPERFAMILY SSF161098 14 266 1.5E-56 T 14-10-2018 IPR035906 MetI-like superfamily LH59_07405 7defa38bcf042189a274d296a6f22fab 299 Gene3D G3DSA:1.10.3720.10 18 275 2.5E-64 T 14-10-2018 IPR035906 MetI-like superfamily LH59_07405 7defa38bcf042189a274d296a6f22fab 299 TIGRFAM TIGR02140 permease_CysW: sulfate ABC transporter, permease protein CysW 16 275 6.4E-129 T 14-10-2018 IPR011866 Sulphate ABC transporter, permease protein CysW GO:0008272|GO:0015116|GO:0016021 LH59_18305 6763454062508457a4484d16f2ed1891 241 Gene3D G3DSA:3.30.450.40 162 236 6.4E-14 T 14-10-2018 IPR029016 GAF-like domain superfamily LH59_18305 6763454062508457a4484d16f2ed1891 241 Pfam PF01614 Bacterial transcriptional regulator 164 230 4.5E-10 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal LH59_18305 6763454062508457a4484d16f2ed1891 241 SMART SM00346 14 103 2.0E-17 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_18305 6763454062508457a4484d16f2ed1891 241 Gene3D G3DSA:3.30.450.40 81 161 7.5E-21 T 14-10-2018 IPR029016 GAF-like domain superfamily LH59_18305 6763454062508457a4484d16f2ed1891 241 Pfam PF09339 IclR helix-turn-helix domain 16 67 4.2E-13 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_18305 6763454062508457a4484d16f2ed1891 241 Gene3D G3DSA:1.10.10.10 3 73 2.1E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_18305 6763454062508457a4484d16f2ed1891 241 SUPERFAMILY SSF46785 16 85 4.01E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_18305 6763454062508457a4484d16f2ed1891 241 SUPERFAMILY SSF55781 80 232 1.5E-34 T 14-10-2018 LH59_13175 a17c0fef8f277e273bfb29b78fea81ea 295 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 62 289 2.8E-58 T 14-10-2018 LH59_13175 a17c0fef8f277e273bfb29b78fea81ea 295 Gene3D G3DSA:3.40.50.720 11 293 3.2E-84 T 14-10-2018 LH59_13175 a17c0fef8f277e273bfb29b78fea81ea 295 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 181 189 2.9E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_13175 a17c0fef8f277e273bfb29b78fea81ea 295 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 140 2.9E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_13175 a17c0fef8f277e273bfb29b78fea81ea 295 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 201 220 2.9E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_13175 a17c0fef8f277e273bfb29b78fea81ea 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 191 7.1E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_13175 a17c0fef8f277e273bfb29b78fea81ea 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 220 7.1E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_13175 a17c0fef8f277e273bfb29b78fea81ea 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 256 276 7.1E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_13175 a17c0fef8f277e273bfb29b78fea81ea 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 54 71 7.1E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_13175 a17c0fef8f277e273bfb29b78fea81ea 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 239 7.1E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_13175 a17c0fef8f277e273bfb29b78fea81ea 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 140 7.1E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_13175 a17c0fef8f277e273bfb29b78fea81ea 295 SUPERFAMILY SSF51735 54 291 5.11E-74 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_13175 a17c0fef8f277e273bfb29b78fea81ea 295 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 188 216 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LH59_27400 5edc8c14974b16225ffd7781ca5a8597 440 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 168 395 4.9E-64 T 14-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 LH59_27400 5edc8c14974b16225ffd7781ca5a8597 440 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 147 440 1.3E-153 T 14-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 LH59_27400 5edc8c14974b16225ffd7781ca5a8597 440 Gene3D G3DSA:3.40.50.620 145 350 1.0E-64 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LH59_27400 5edc8c14974b16225ffd7781ca5a8597 440 SUPERFAMILY SSF52402 143 348 1.5E-73 T 14-10-2018 LH59_27400 5edc8c14974b16225ffd7781ca5a8597 440 Hamap MF_00064 Sulfate adenylyltransferase subunit 2 [cysD]. 142 440 55.383 T 14-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 LH59_19740 8084ee0238f7f00f50a5fea76a1edc0f 244 SUPERFAMILY SSF53213 1 244 2.49E-80 T 14-10-2018 LH59_19740 8084ee0238f7f00f50a5fea76a1edc0f 244 Gene3D G3DSA:3.40.830.10 1 244 1.1E-79 T 14-10-2018 LH59_19740 8084ee0238f7f00f50a5fea76a1edc0f 244 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 21 243 2.5E-51 T 14-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 LH59_19740 8084ee0238f7f00f50a5fea76a1edc0f 244 PIRSF PIRSF006157 1 244 4.1E-81 T 14-10-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 LH59_05570 1320147288da2072f40e3ec88c287b9a 325 Gene3D G3DSA:3.40.190.150 28 314 2.8E-103 T 14-10-2018 LH59_05570 1320147288da2072f40e3ec88c287b9a 325 Gene3D G3DSA:3.40.190.10 126 249 2.8E-103 T 14-10-2018 LH59_05570 1320147288da2072f40e3ec88c287b9a 325 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 3 23 0.0015 T 14-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal LH59_05570 1320147288da2072f40e3ec88c287b9a 325 PIRSF PIRSF017082 1 324 3.0E-71 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_05570 1320147288da2072f40e3ec88c287b9a 325 SUPERFAMILY SSF53850 109 278 3.69E-9 T 14-10-2018 LH59_05570 1320147288da2072f40e3ec88c287b9a 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 320 3.6E-76 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_21995 fa0623e07abf9bb98aa39e6e453c3de8 1080 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 304 311 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 LH59_21995 fa0623e07abf9bb98aa39e6e453c3de8 1080 Gene3D G3DSA:1.10.1030.10 410 555 1.8E-49 T 14-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 LH59_21995 fa0623e07abf9bb98aa39e6e453c3de8 1080 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1073 13.445 T 14-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 LH59_21995 fa0623e07abf9bb98aa39e6e453c3de8 1080 SUPERFAMILY SSF56059 128 408 9.19E-107 T 14-10-2018 LH59_21995 fa0623e07abf9bb98aa39e6e453c3de8 1080 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1065 13.226 T 14-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 LH59_21995 fa0623e07abf9bb98aa39e6e453c3de8 1080 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 341 9.7E-70 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 LH59_21995 fa0623e07abf9bb98aa39e6e453c3de8 1080 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 675 876 1.9E-36 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 LH59_21995 fa0623e07abf9bb98aa39e6e453c3de8 1080 SMART SM00851 957 1044 5.6E-32 T 14-10-2018 IPR011607 Methylglyoxal synthase-like domain LH59_21995 fa0623e07abf9bb98aa39e6e453c3de8 1080 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 429 549 1.6E-42 T 14-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 LH59_21995 fa0623e07abf9bb98aa39e6e453c3de8 1080 SUPERFAMILY SSF52440 558 677 4.32E-49 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily LH59_21995 fa0623e07abf9bb98aa39e6e453c3de8 1080 Gene3D G3DSA:3.40.50.20 1 116 1.5E-49 T 14-10-2018 LH59_21995 fa0623e07abf9bb98aa39e6e453c3de8 1080 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 711 725 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 LH59_21995 fa0623e07abf9bb98aa39e6e453c3de8 1080 SUPERFAMILY SSF48108 403 556 3.14E-54 T 14-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 LH59_21995 fa0623e07abf9bb98aa39e6e453c3de8 1080 Gene3D G3DSA:3.40.50.20 556 664 6.2E-49 T 14-10-2018 LH59_21995 fa0623e07abf9bb98aa39e6e453c3de8 1080 SUPERFAMILY SSF56059 675 935 2.12E-103 T 14-10-2018 LH59_21995 fa0623e07abf9bb98aa39e6e453c3de8 1080 Gene3D G3DSA:3.30.470.20 667 937 5.2E-119 T 14-10-2018 LH59_21995 fa0623e07abf9bb98aa39e6e453c3de8 1080 Pfam PF02142 MGS-like domain 958 1044 1.2E-20 T 14-10-2018 IPR011607 Methylglyoxal synthase-like domain LH59_21995 fa0623e07abf9bb98aa39e6e453c3de8 1080 SMART SM01096 426 549 2.3E-74 T 14-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 LH59_21995 fa0623e07abf9bb98aa39e6e453c3de8 1080 Gene3D G3DSA:3.40.50.1380 938 1078 8.2E-38 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily LH59_21995 fa0623e07abf9bb98aa39e6e453c3de8 1080 SUPERFAMILY SSF52440 1 127 2.01E-48 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily LH59_21995 fa0623e07abf9bb98aa39e6e453c3de8 1080 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1054 0.0 T 14-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 LH59_21995 fa0623e07abf9bb98aa39e6e453c3de8 1080 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 840 847 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 LH59_21995 fa0623e07abf9bb98aa39e6e453c3de8 1080 Gene3D G3DSA:3.30.470.20 120 409 4.4E-128 T 14-10-2018 LH59_21995 fa0623e07abf9bb98aa39e6e453c3de8 1080 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 387 405 3.8E-66 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 LH59_21995 fa0623e07abf9bb98aa39e6e453c3de8 1080 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 246 263 3.8E-66 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 LH59_21995 fa0623e07abf9bb98aa39e6e453c3de8 1080 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 304 333 3.8E-66 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 LH59_21995 fa0623e07abf9bb98aa39e6e453c3de8 1080 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 175 187 3.8E-66 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 LH59_21995 fa0623e07abf9bb98aa39e6e453c3de8 1080 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 3.8E-66 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 LH59_21995 fa0623e07abf9bb98aa39e6e453c3de8 1080 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 211 230 3.8E-66 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 LH59_21995 fa0623e07abf9bb98aa39e6e453c3de8 1080 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 3.8E-66 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 LH59_21995 fa0623e07abf9bb98aa39e6e453c3de8 1080 SUPERFAMILY SSF52335 937 1075 2.35E-39 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily LH59_02985 3c2d7199ecf2ced4d814e1ec1164e38a 447 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 198 431 4.7E-9 T 14-10-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0044237|GO:0051537|GO:0055114 LH59_02985 3c2d7199ecf2ced4d814e1ec1164e38a 447 Pfam PF00355 Rieske [2Fe-2S] domain 40 125 3.9E-19 T 14-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 LH59_02985 3c2d7199ecf2ced4d814e1ec1164e38a 447 Gene3D G3DSA:3.90.380.10 23 426 3.6E-99 T 14-10-2018 LH59_02985 3c2d7199ecf2ced4d814e1ec1164e38a 447 SUPERFAMILY SSF50022 12 155 7.07E-44 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 LH59_02985 3c2d7199ecf2ced4d814e1ec1164e38a 447 SUPERFAMILY SSF55961 159 434 3.38E-53 T 14-10-2018 LH59_02985 3c2d7199ecf2ced4d814e1ec1164e38a 447 Gene3D G3DSA:2.102.10.10 37 168 3.6E-99 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 LH59_02985 3c2d7199ecf2ced4d814e1ec1164e38a 447 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 24 49 5.1E-34 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 LH59_02985 3c2d7199ecf2ced4d814e1ec1164e38a 447 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 185 207 5.1E-34 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 LH59_02985 3c2d7199ecf2ced4d814e1ec1164e38a 447 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 143 169 5.1E-34 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 LH59_02985 3c2d7199ecf2ced4d814e1ec1164e38a 447 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 54 69 5.1E-34 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 LH59_02985 3c2d7199ecf2ced4d814e1ec1164e38a 447 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 75 95 5.1E-34 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 LH59_02985 3c2d7199ecf2ced4d814e1ec1164e38a 447 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 97 117 5.1E-34 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 LH59_04140 562f4f756515aec08c9193dfdc54092e 490 SUPERFAMILY SSF161093 318 489 7.72E-44 T 14-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 LH59_04140 562f4f756515aec08c9193dfdc54092e 490 SUPERFAMILY SSF54631 177 312 1.52E-27 T 14-10-2018 LH59_04140 562f4f756515aec08c9193dfdc54092e 490 Gene3D G3DSA:3.10.580.10 174 301 5.9E-43 T 14-10-2018 LH59_04140 562f4f756515aec08c9193dfdc54092e 490 SMART SM00116 185 238 1.2 T 14-10-2018 IPR000644 CBS domain LH59_04140 562f4f756515aec08c9193dfdc54092e 490 SMART SM00116 249 297 0.0023 T 14-10-2018 IPR000644 CBS domain LH59_04140 562f4f756515aec08c9193dfdc54092e 490 Pfam PF00571 CBS domain 242 296 7.9E-7 T 14-10-2018 IPR000644 CBS domain LH59_04140 562f4f756515aec08c9193dfdc54092e 490 Pfam PF00571 CBS domain 178 234 6.1E-5 T 14-10-2018 IPR000644 CBS domain LH59_04140 562f4f756515aec08c9193dfdc54092e 490 SUPERFAMILY SSF158791 56 175 3.4E-28 T 14-10-2018 LH59_04140 562f4f756515aec08c9193dfdc54092e 490 SMART SM00924 75 178 4.8E-38 T 14-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain LH59_04140 562f4f756515aec08c9193dfdc54092e 490 Pfam PF03448 MgtE intracellular N domain 75 176 1.8E-26 T 14-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain LH59_04140 562f4f756515aec08c9193dfdc54092e 490 TIGRFAM TIGR00400 mgtE: magnesium transporter 59 489 4.7E-82 T 14-10-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 LH59_04140 562f4f756515aec08c9193dfdc54092e 490 Gene3D G3DSA:1.25.60.10 49 173 2.5E-18 T 14-10-2018 IPR038076 MgtE, N-terminal domain superfamily LH59_04140 562f4f756515aec08c9193dfdc54092e 490 Pfam PF01769 Divalent cation transporter 361 482 6.9E-23 T 14-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 LH59_04140 562f4f756515aec08c9193dfdc54092e 490 Gene3D G3DSA:1.10.357.20 316 489 6.9E-45 T 14-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain LH59_04635 ef415865cd1aad135d730993f999f089 467 Gene3D G3DSA:1.20.1740.10 16 462 5.2E-86 T 14-10-2018 LH59_04635 ef415865cd1aad135d730993f999f089 467 Pfam PF13520 Amino acid permease 26 422 9.7E-50 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 LH59_04635 ef415865cd1aad135d730993f999f089 467 PIRSF PIRSF006060 1 467 5.1E-81 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 LH59_26485 7fdd3dcd7ebd71d182ad31baff9bb51a 208 SUPERFAMILY SSF56784 2 207 2.17E-40 T 14-10-2018 IPR036412 HAD-like superfamily LH59_26485 7fdd3dcd7ebd71d182ad31baff9bb51a 208 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 176 9.5E-28 T 14-10-2018 LH59_26485 7fdd3dcd7ebd71d182ad31baff9bb51a 208 Gene3D G3DSA:1.10.150.240 17 81 1.2E-32 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 LH59_26485 7fdd3dcd7ebd71d182ad31baff9bb51a 208 Gene3D G3DSA:3.40.50.1000 8 199 1.2E-32 T 14-10-2018 IPR023214 HAD superfamily LH59_09685 107c7bc7516a8ad76c70104d5d1ef195 805 Pfam PF03147 Ferredoxin-fold anticodon binding domain 703 804 1.4E-21 T 14-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 LH59_09685 107c7bc7516a8ad76c70104d5d1ef195 805 Gene3D G3DSA:2.40.50.140 39 154 7.7E-70 T 14-10-2018 LH59_09685 107c7bc7516a8ad76c70104d5d1ef195 805 Gene3D G3DSA:3.30.70.380 704 805 1.7E-14 T 14-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 LH59_09685 107c7bc7516a8ad76c70104d5d1ef195 805 SUPERFAMILY SSF46955 402 473 3.85E-19 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily LH59_09685 107c7bc7516a8ad76c70104d5d1ef195 805 Pfam PF03483 B3/4 domain 213 385 9.5E-60 T 14-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 LH59_09685 107c7bc7516a8ad76c70104d5d1ef195 805 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 798 43.092 T 14-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 LH59_09685 107c7bc7516a8ad76c70104d5d1ef195 805 Pfam PF03484 tRNA synthetase B5 domain 404 469 2.5E-19 T 14-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 LH59_09685 107c7bc7516a8ad76c70104d5d1ef195 805 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 804 1.1E-221 T 14-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 LH59_09685 107c7bc7516a8ad76c70104d5d1ef195 805 Gene3D G3DSA:3.30.930.10 488 693 2.7E-58 T 14-10-2018 LH59_09685 107c7bc7516a8ad76c70104d5d1ef195 805 SMART SM00873 212 385 8.4E-79 T 14-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 LH59_09685 107c7bc7516a8ad76c70104d5d1ef195 805 Gene3D G3DSA:3.30.56.10 401 474 9.2E-25 T 14-10-2018 LH59_09685 107c7bc7516a8ad76c70104d5d1ef195 805 SMART SM00874 401 469 1.9E-28 T 14-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 LH59_09685 107c7bc7516a8ad76c70104d5d1ef195 805 Gene3D G3DSA:3.50.40.10 197 394 2.2E-66 T 14-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 LH59_09685 107c7bc7516a8ad76c70104d5d1ef195 805 Pfam PF01588 Putative tRNA binding domain 45 145 5.9E-26 T 14-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 LH59_09685 107c7bc7516a8ad76c70104d5d1ef195 805 SUPERFAMILY SSF50249 39 197 1.59E-49 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_09685 107c7bc7516a8ad76c70104d5d1ef195 805 SMART SM00896 703 804 3.9E-24 T 14-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 LH59_09685 107c7bc7516a8ad76c70104d5d1ef195 805 SUPERFAMILY SSF56037 196 390 6.8E-66 T 14-10-2018 LH59_09685 107c7bc7516a8ad76c70104d5d1ef195 805 SUPERFAMILY SSF54991 698 804 2.75E-18 T 14-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 LH59_09685 107c7bc7516a8ad76c70104d5d1ef195 805 Gene3D G3DSA:3.30.56.10 5 181 7.7E-70 T 14-10-2018 LH59_09685 107c7bc7516a8ad76c70104d5d1ef195 805 SUPERFAMILY SSF55681 465 691 1.34E-49 T 14-10-2018 LH59_26935 3cca2a8096ef035f5a7aa5bbf64a10de 412 Gene3D G3DSA:1.20.1530.10 12 401 2.2E-147 T 14-10-2018 IPR023171 Na/H antiporter domain superfamily LH59_26935 3cca2a8096ef035f5a7aa5bbf64a10de 412 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 18 393 7.4E-139 T 14-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 LH59_26935 3cca2a8096ef035f5a7aa5bbf64a10de 412 Pfam PF06965 Na+/H+ antiporter 1 17 393 1.8E-147 T 14-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 LH59_26935 3cca2a8096ef035f5a7aa5bbf64a10de 412 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 15 404 23.524 T 14-10-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 LH59_22125 37fe6fc8c9be1338964373dbce465c13 244 Gene3D G3DSA:3.90.226.10 2 241 3.0E-64 T 14-10-2018 LH59_22125 37fe6fc8c9be1338964373dbce465c13 244 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 225 6.9E-50 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 LH59_22125 37fe6fc8c9be1338964373dbce465c13 244 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 101 121 - T 14-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 LH59_22125 37fe6fc8c9be1338964373dbce465c13 244 SUPERFAMILY SSF52096 7 235 1.61E-64 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily LH59_19700 f4f20036e188400d7d743a6a8cb0ab9d 901 PRINTS PR00415 Aconitase family signature 146 159 3.3E-41 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 LH59_19700 f4f20036e188400d7d743a6a8cb0ab9d 901 PRINTS PR00415 Aconitase family signature 371 385 3.3E-41 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 LH59_19700 f4f20036e188400d7d743a6a8cb0ab9d 901 PRINTS PR00415 Aconitase family signature 170 178 3.3E-41 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 LH59_19700 f4f20036e188400d7d743a6a8cb0ab9d 901 PRINTS PR00415 Aconitase family signature 495 508 3.3E-41 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 LH59_19700 f4f20036e188400d7d743a6a8cb0ab9d 901 PRINTS PR00415 Aconitase family signature 291 304 3.3E-41 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 LH59_19700 f4f20036e188400d7d743a6a8cb0ab9d 901 PRINTS PR00415 Aconitase family signature 277 290 3.3E-41 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 LH59_19700 f4f20036e188400d7d743a6a8cb0ab9d 901 PRINTS PR00415 Aconitase family signature 201 214 3.3E-41 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 LH59_19700 f4f20036e188400d7d743a6a8cb0ab9d 901 PRINTS PR00415 Aconitase family signature 215 230 3.3E-41 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 LH59_19700 f4f20036e188400d7d743a6a8cb0ab9d 901 PRINTS PR00415 Aconitase family signature 433 444 3.3E-41 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 LH59_19700 f4f20036e188400d7d743a6a8cb0ab9d 901 SUPERFAMILY SSF52016 637 899 1.67E-82 T 14-10-2018 LH59_19700 f4f20036e188400d7d743a6a8cb0ab9d 901 Gene3D G3DSA:3.20.19.10 656 900 3.2E-104 T 14-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 LH59_19700 f4f20036e188400d7d743a6a8cb0ab9d 901 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 18 899 0.0 T 14-10-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 LH59_19700 f4f20036e188400d7d743a6a8cb0ab9d 901 Pfam PF00694 Aconitase C-terminal domain 693 825 5.4E-40 T 14-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 LH59_19700 f4f20036e188400d7d743a6a8cb0ab9d 901 Pfam PF00330 Aconitase family (aconitate hydratase) 69 564 2.2E-177 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 LH59_19700 f4f20036e188400d7d743a6a8cb0ab9d 901 ProSitePatterns PS00450 Aconitase family signature 1. 429 445 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 LH59_19700 f4f20036e188400d7d743a6a8cb0ab9d 901 SUPERFAMILY SSF53732 4 618 4.97E-213 T 14-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 LH59_19700 f4f20036e188400d7d743a6a8cb0ab9d 901 Gene3D G3DSA:1.10.1440.20 592 653 2.9E-10 T 14-10-2018 LH59_19700 f4f20036e188400d7d743a6a8cb0ab9d 901 Gene3D G3DSA:3.30.499.20 3 371 1.4E-158 T 14-10-2018 LH59_19700 f4f20036e188400d7d743a6a8cb0ab9d 901 Gene3D G3DSA:3.30.499.10 372 591 5.3E-93 T 14-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 LH59_19700 f4f20036e188400d7d743a6a8cb0ab9d 901 ProSitePatterns PS01244 Aconitase family signature 2. 495 508 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 LH59_06865 6d8ca7d9880ac838a1f4882a9db48292 483 Gene3D G3DSA:3.30.1330.120 285 426 7.2E-210 T 14-10-2018 LH59_06865 6d8ca7d9880ac838a1f4882a9db48292 483 Pfam PF03972 MmgE/PrpD family 18 467 1.4E-165 T 14-10-2018 IPR005656 MmgE/PrpD GO:0016829 LH59_06865 6d8ca7d9880ac838a1f4882a9db48292 483 Gene3D G3DSA:1.10.4100.10 22 461 7.2E-210 T 14-10-2018 LH59_06865 6d8ca7d9880ac838a1f4882a9db48292 483 SUPERFAMILY SSF103378 12 482 7.72E-167 T 14-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 LH59_06865 6d8ca7d9880ac838a1f4882a9db48292 483 TIGRFAM TIGR02330 prpD: 2-methylcitrate dehydratase 13 483 4.8E-267 T 14-10-2018 IPR012705 2-methylcitrate dehydratase PrpD GO:0019629|GO:0047547|GO:0051537 KEGG: 00640+4.2.1.79 LH59_09515 31940a6aaae528ea0c59b0fda3b782c3 426 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 420 5.9E-142 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 LH59_09515 31940a6aaae528ea0c59b0fda3b782c3 426 PIRSF PIRSF006066 1 426 3.3E-142 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 LH59_09515 31940a6aaae528ea0c59b0fda3b782c3 426 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 7 417 1.4E-112 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit LH59_09510 3f9640948ff19bbba2d03a2a13c43546 338 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 36 291 1.0E-82 T 14-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 LH59_09510 3f9640948ff19bbba2d03a2a13c43546 338 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 36 318 7.0E-95 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 LH59_09510 3f9640948ff19bbba2d03a2a13c43546 338 PIRSF PIRSF006470 3 335 1.5E-118 T 14-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 LH59_09510 3f9640948ff19bbba2d03a2a13c43546 338 Gene3D G3DSA:3.40.190.170 29 338 9.8E-108 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily LH59_12380 edecc872d4342f2218e156150caa9bf8 250 TIGRFAM TIGR02001 gcw_chp: conserved hypothetical protein 1 250 8.8E-50 T 14-10-2018 IPR010239 Conserved hypothetical protein CHP02001 LH59_12380 edecc872d4342f2218e156150caa9bf8 250 Pfam PF09694 Bacterial protein of unknown function (Gcw_chp) 29 250 1.6E-49 T 14-10-2018 IPR010239 Conserved hypothetical protein CHP02001 LH59_13920 4141e38ce2ca1c0a45cab3b8ef702d47 226 SUPERFAMILY SSF52499 14 208 4.58E-43 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 LH59_13920 4141e38ce2ca1c0a45cab3b8ef702d47 226 Pfam PF00857 Isochorismatase family 20 172 7.8E-19 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 LH59_13920 4141e38ce2ca1c0a45cab3b8ef702d47 226 Gene3D G3DSA:3.40.50.850 12 215 6.4E-46 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 LH59_01425 b37da9efc53ee957aabe5785d29a110f 641 Pfam PF02872 5'-nucleotidase, C-terminal domain 444 590 3.3E-30 T 14-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 LH59_01425 b37da9efc53ee957aabe5785d29a110f 641 Gene3D G3DSA:3.90.780.10 427 621 2.5E-43 T 14-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 LH59_01425 b37da9efc53ee957aabe5785d29a110f 641 SUPERFAMILY SSF55816 439 615 1.16E-36 T 14-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 LH59_01425 b37da9efc53ee957aabe5785d29a110f 641 ProSitePatterns PS00786 5'-nucleotidase signature 2. 137 148 - T 14-10-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 LH59_01425 b37da9efc53ee957aabe5785d29a110f 641 PRINTS PR01607 Apyrase family signature 482 505 1.6E-34 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 LH59_01425 b37da9efc53ee957aabe5785d29a110f 641 PRINTS PR01607 Apyrase family signature 245 262 1.6E-34 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 LH59_01425 b37da9efc53ee957aabe5785d29a110f 641 PRINTS PR01607 Apyrase family signature 564 583 1.6E-34 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 LH59_01425 b37da9efc53ee957aabe5785d29a110f 641 PRINTS PR01607 Apyrase family signature 264 287 1.6E-34 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 LH59_01425 b37da9efc53ee957aabe5785d29a110f 641 PRINTS PR01607 Apyrase family signature 312 332 1.6E-34 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 LH59_01425 b37da9efc53ee957aabe5785d29a110f 641 PRINTS PR01607 Apyrase family signature 46 64 1.6E-34 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 LH59_01425 b37da9efc53ee957aabe5785d29a110f 641 Gene3D G3DSA:3.60.21.10 37 403 6.9E-104 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like LH59_01425 b37da9efc53ee957aabe5785d29a110f 641 SUPERFAMILY SSF56300 42 372 3.56E-69 T 14-10-2018 LH59_01425 b37da9efc53ee957aabe5785d29a110f 641 ProSitePatterns PS00785 5'-nucleotidase signature 1. 48 60 - T 14-10-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 LH59_01425 b37da9efc53ee957aabe5785d29a110f 641 Pfam PF00149 Calcineurin-like phosphoesterase 48 281 1.3E-7 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 LH59_16690 a220521cea7ab7b03509d9647a239ef6 436 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 32 416 4.2E-86 T 14-10-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase LH59_16690 a220521cea7ab7b03509d9647a239ef6 436 Pfam PF07687 Peptidase dimerisation domain 213 323 1.1E-14 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain LH59_16690 a220521cea7ab7b03509d9647a239ef6 436 SUPERFAMILY SSF53187 17 430 9.14E-58 T 14-10-2018 LH59_16690 a220521cea7ab7b03509d9647a239ef6 436 SUPERFAMILY SSF55031 216 328 1.4E-12 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain LH59_16690 a220521cea7ab7b03509d9647a239ef6 436 Gene3D G3DSA:3.40.630.10 38 430 3.0E-147 T 14-10-2018 LH59_16690 a220521cea7ab7b03509d9647a239ef6 436 Pfam PF01546 Peptidase family M20/M25/M40 109 426 5.7E-30 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 LH59_16690 a220521cea7ab7b03509d9647a239ef6 436 Gene3D G3DSA:3.30.70.360 216 342 3.0E-147 T 14-10-2018 LH59_23135 6e00f58ed624c9ede41093534f2e6004 216 SMART SM00421 152 209 1.5E-21 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_23135 6e00f58ed624c9ede41093534f2e6004 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 3.4E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_23135 6e00f58ed624c9ede41093534f2e6004 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 3.4E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_23135 6e00f58ed624c9ede41093534f2e6004 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 3.4E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_23135 6e00f58ed624c9ede41093534f2e6004 216 SUPERFAMILY SSF46894 143 215 2.58E-21 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LH59_23135 6e00f58ed624c9ede41093534f2e6004 216 SMART SM00448 3 117 6.5E-21 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_23135 6e00f58ed624c9ede41093534f2e6004 216 Gene3D G3DSA:1.10.10.10 105 216 5.1E-32 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_23135 6e00f58ed624c9ede41093534f2e6004 216 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_23135 6e00f58ed624c9ede41093534f2e6004 216 SUPERFAMILY SSF52172 4 155 4.27E-27 T 14-10-2018 IPR011006 CheY-like superfamily LH59_23135 6e00f58ed624c9ede41093534f2e6004 216 Pfam PF00072 Response regulator receiver domain 5 110 4.3E-19 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_23135 6e00f58ed624c9ede41093534f2e6004 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 6.1E-20 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_23135 6e00f58ed624c9ede41093534f2e6004 216 Gene3D G3DSA:3.40.50.2300 3 104 2.3E-17 T 14-10-2018 LH59_01215 150990cfdb8f7e723ad2fa97fa596508 162 Pfam PF13412 Winged helix-turn-helix DNA-binding 11 57 6.9E-18 T 14-10-2018 LH59_01215 150990cfdb8f7e723ad2fa97fa596508 162 Gene3D G3DSA:1.10.10.10 12 63 3.9E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_01215 150990cfdb8f7e723ad2fa97fa596508 162 SUPERFAMILY SSF54909 73 157 2.55E-12 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel LH59_01215 150990cfdb8f7e723ad2fa97fa596508 162 Pfam PF01037 Lrp/AsnC ligand binding domain 77 149 2.1E-14 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LH59_01215 150990cfdb8f7e723ad2fa97fa596508 162 SUPERFAMILY SSF46785 11 70 3.86E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_01215 150990cfdb8f7e723ad2fa97fa596508 162 SMART SM00344 11 120 2.6E-33 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 LH59_01215 150990cfdb8f7e723ad2fa97fa596508 162 Gene3D G3DSA:3.30.70.920 64 148 3.6E-17 T 14-10-2018 LH59_01215 150990cfdb8f7e723ad2fa97fa596508 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 11 27 7.1E-11 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_01215 150990cfdb8f7e723ad2fa97fa596508 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 27 38 7.1E-11 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_01215 150990cfdb8f7e723ad2fa97fa596508 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 38 57 7.1E-11 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_25875 5f6bf661b7d75fc756f1a1dc2a8e187b 621 Pfam PF00920 Dehydratase family 34 610 2.6E-217 T 14-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 LH59_25875 5f6bf661b7d75fc756f1a1dc2a8e187b 621 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 613 4.1E-251 T 14-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 LH59_25875 5f6bf661b7d75fc756f1a1dc2a8e187b 621 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 613 44.762 T 14-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 LH59_25875 5f6bf661b7d75fc756f1a1dc2a8e187b 621 Gene3D G3DSA:3.50.30.80 424 576 1.8E-56 T 14-10-2018 LH59_25875 5f6bf661b7d75fc756f1a1dc2a8e187b 621 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 14-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 LH59_25875 5f6bf661b7d75fc756f1a1dc2a8e187b 621 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 512 523 - T 14-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 LH59_25875 5f6bf661b7d75fc756f1a1dc2a8e187b 621 SUPERFAMILY SSF143975 3 423 8.63E-131 T 14-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 LH59_25875 5f6bf661b7d75fc756f1a1dc2a8e187b 621 SUPERFAMILY SSF52016 424 616 5.65E-61 T 14-10-2018 LH59_24430 30f56890c29afe0af426c42239617dd0 256 TIGRFAM TIGR02315 ABC_phnC: phosphonate ABC transporter, ATP-binding protein 5 250 1.5E-88 T 14-10-2018 IPR012693 ABC transporter, phosphonate import, PhnC GO:0005524|GO:0015416|GO:0015716|GO:0016020 LH59_24430 30f56890c29afe0af426c42239617dd0 256 SUPERFAMILY SSF52540 5 241 2.66E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_24430 30f56890c29afe0af426c42239617dd0 256 Pfam PF00005 ABC transporter 21 181 9.7E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_24430 30f56890c29afe0af426c42239617dd0 256 Gene3D G3DSA:3.40.50.300 2 248 5.9E-63 T 14-10-2018 LH59_24430 30f56890c29afe0af426c42239617dd0 256 SMART SM00382 30 230 1.5E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_24430 30f56890c29afe0af426c42239617dd0 256 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_07810 b6bae04cfb6bfe608541f00a3f588dc0 124 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 94 21.539 T 14-10-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 LH59_07810 b6bae04cfb6bfe608541f00a3f588dc0 124 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 93 7.8E-33 T 14-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_07810 b6bae04cfb6bfe608541f00a3f588dc0 124 Pfam PF01250 Ribosomal protein S6 3 91 2.9E-27 T 14-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_07810 b6bae04cfb6bfe608541f00a3f588dc0 124 SUPERFAMILY SSF54995 1 103 3.79E-36 T 14-10-2018 IPR035980 Ribosomal protein S6 superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_07810 b6bae04cfb6bfe608541f00a3f588dc0 124 Gene3D G3DSA:3.30.70.60 1 92 1.0E-31 T 14-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 LH59_11140 d8d59d2405057a3dc8552bca8fde66dd 504 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 66 422 9.4E-83 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain LH59_11140 d8d59d2405057a3dc8552bca8fde66dd 504 Gene3D G3DSA:3.40.190.10 181 486 7.1E-123 T 14-10-2018 LH59_11140 d8d59d2405057a3dc8552bca8fde66dd 504 Gene3D G3DSA:3.10.105.10 256 476 7.1E-123 T 14-10-2018 LH59_11140 d8d59d2405057a3dc8552bca8fde66dd 504 SUPERFAMILY SSF53850 23 501 6.33E-130 T 14-10-2018 LH59_11140 d8d59d2405057a3dc8552bca8fde66dd 504 Gene3D G3DSA:3.90.76.10 32 180 7.1E-123 T 14-10-2018 LH59_11140 d8d59d2405057a3dc8552bca8fde66dd 504 PIRSF PIRSF002741 15 503 6.8E-105 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 LH59_05795 bb376c72dcae90d16d7f0dadf5f45831 2017 SUPERFAMILY SSF52980 1662 1772 2.84E-15 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 LH59_05795 bb376c72dcae90d16d7f0dadf5f45831 2017 Pfam PF13087 AAA domain 1439 1617 8.8E-13 T 14-10-2018 LH59_05795 bb376c72dcae90d16d7f0dadf5f45831 2017 Gene3D G3DSA:3.40.50.300 1447 1630 1.4E-26 T 14-10-2018 LH59_05795 bb376c72dcae90d16d7f0dadf5f45831 2017 Gene3D G3DSA:3.40.960.10 1664 1768 1.2E-16 T 14-10-2018 LH59_05795 bb376c72dcae90d16d7f0dadf5f45831 2017 Pfam PF13195 Protein of unknown function (DUF4011) 417 590 2.4E-41 T 14-10-2018 IPR025103 Protein of unknown function DUF4011 LH59_05795 bb376c72dcae90d16d7f0dadf5f45831 2017 SUPERFAMILY SSF52540 694 1645 4.99E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_05795 bb376c72dcae90d16d7f0dadf5f45831 2017 Pfam PF11784 Protein of unknown function (DUF3320) 1851 1898 2.4E-15 T 14-10-2018 IPR021754 Protein of unknown function DUF3320 LH59_05795 bb376c72dcae90d16d7f0dadf5f45831 2017 Gene3D G3DSA:3.40.50.300 1240 1423 9.7E-15 T 14-10-2018 LH59_05795 bb376c72dcae90d16d7f0dadf5f45831 2017 Gene3D G3DSA:3.40.50.300 650 930 8.0E-18 T 14-10-2018 LH59_05795 bb376c72dcae90d16d7f0dadf5f45831 2017 Pfam PF13086 AAA domain 1360 1402 2.8E-6 T 14-10-2018 LH59_14865 e6f622061fcdee8e17fc305744857f81 330 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 5 179 1.6E-39 T 14-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain LH59_14865 e6f622061fcdee8e17fc305744857f81 330 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 231 317 1.7E-12 T 14-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal LH59_14865 e6f622061fcdee8e17fc305744857f81 330 SMART SM00833 231 321 2.8E-7 T 14-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal LH59_14865 e6f622061fcdee8e17fc305744857f81 330 Gene3D G3DSA:3.40.50.300 1 196 9.7E-52 T 14-10-2018 LH59_14865 e6f622061fcdee8e17fc305744857f81 330 SUPERFAMILY SSF90002 231 304 7.19E-8 T 14-10-2018 LH59_14865 e6f622061fcdee8e17fc305744857f81 330 SUPERFAMILY SSF52540 3 181 5.13E-25 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_00400 acd368743de75bfe98d852e31960a498 321 PIRSF PIRSF017082 1 320 1.8E-73 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_00400 acd368743de75bfe98d852e31960a498 321 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 316 9.4E-84 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_00400 acd368743de75bfe98d852e31960a498 321 Gene3D G3DSA:3.40.190.150 26 311 4.6E-106 T 14-10-2018 LH59_00400 acd368743de75bfe98d852e31960a498 321 Gene3D G3DSA:3.40.190.10 123 246 4.6E-106 T 14-10-2018 LH59_00400 acd368743de75bfe98d852e31960a498 321 SUPERFAMILY SSF53850 84 284 1.19E-10 T 14-10-2018 LH59_20140 ca545e3078850add862938bb1e823e09 240 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 181 5.7E-23 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 LH59_20140 ca545e3078850add862938bb1e823e09 240 SUPERFAMILY SSF52096 3 237 2.71E-39 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily LH59_20140 ca545e3078850add862938bb1e823e09 240 Gene3D G3DSA:3.90.226.10 1 240 2.3E-62 T 14-10-2018 LH59_17360 86d675366152d6106c63c34a94d2a885 559 Pfam PF01266 FAD dependent oxidoreductase 39 370 7.9E-47 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 LH59_17360 86d675366152d6106c63c34a94d2a885 559 Gene3D G3DSA:3.30.9.10 116 365 1.1E-112 T 14-10-2018 LH59_17360 86d675366152d6106c63c34a94d2a885 559 Gene3D G3DSA:3.50.50.60 39 407 1.1E-112 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_17360 86d675366152d6106c63c34a94d2a885 559 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 358 364 2.8E-24 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 LH59_17360 86d675366152d6106c63c34a94d2a885 559 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 388 400 2.8E-24 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 LH59_17360 86d675366152d6106c63c34a94d2a885 559 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 112 124 2.8E-24 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 LH59_17360 86d675366152d6106c63c34a94d2a885 559 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 38 50 2.8E-24 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 LH59_17360 86d675366152d6106c63c34a94d2a885 559 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 67 79 2.8E-24 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 LH59_17360 86d675366152d6106c63c34a94d2a885 559 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 51 61 2.8E-24 T 14-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 LH59_17360 86d675366152d6106c63c34a94d2a885 559 SUPERFAMILY SSF51905 36 339 4.81E-33 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_17360 86d675366152d6106c63c34a94d2a885 559 Gene3D G3DSA:1.10.8.870 437 558 1.7E-25 T 14-10-2018 IPR038299 Alpha-glycerophosphate oxidase, C-terminal domain superfamily KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 LH59_17360 86d675366152d6106c63c34a94d2a885 559 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 420 534 1.3E-26 T 14-10-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 LH59_18535 2812aa518d68c336443dae14fd6955c9 352 Gene3D G3DSA:3.40.50.300 75 352 1.4E-104 T 14-10-2018 LH59_18535 2812aa518d68c336443dae14fd6955c9 352 TIGRFAM TIGR03707 PPK2_P_aer: polyphosphate kinase 2 111 336 3.9E-119 T 14-10-2018 IPR022486 Polyphosphate kinase 2, PA0141 GO:0006793|GO:0008976 KEGG: 00190+2.7.4.1 LH59_18535 2812aa518d68c336443dae14fd6955c9 352 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 113 335 2.9E-106 T 14-10-2018 IPR022488 Polyphosphate kinase-2-related LH59_18535 2812aa518d68c336443dae14fd6955c9 352 SUPERFAMILY SSF52540 142 322 1.97E-30 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_18535 2812aa518d68c336443dae14fd6955c9 352 PIRSF PIRSF028756 75 345 1.2E-123 T 14-10-2018 IPR016898 Polyphosphate kinase 2 KEGG: 00190+2.7.4.1 LH59_22570 e3cea459ea6ee9d46a84d3078ad58608 257 SUPERFAMILY SSF51735 9 255 1.22E-63 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_22570 e3cea459ea6ee9d46a84d3078ad58608 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 254 1.7E-80 T 14-10-2018 LH59_22570 e3cea459ea6ee9d46a84d3078ad58608 257 Gene3D G3DSA:3.40.50.720 2 257 3.4E-55 T 14-10-2018 LH59_22570 e3cea459ea6ee9d46a84d3078ad58608 257 PIRSF PIRSF000094 4 257 1.0E-86 T 14-10-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 LH59_22570 e3cea459ea6ee9d46a84d3078ad58608 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 1.5E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_22570 e3cea459ea6ee9d46a84d3078ad58608 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.5E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_22570 e3cea459ea6ee9d46a84d3078ad58608 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 1.5E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_22570 e3cea459ea6ee9d46a84d3078ad58608 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 1.5E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_22570 e3cea459ea6ee9d46a84d3078ad58608 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 1.5E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25840 8ad9c783fd3c112054e5a7f439d6bf94 239 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_25840 8ad9c783fd3c112054e5a7f439d6bf94 239 SUPERFAMILY SSF52540 6 233 1.63E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_25840 8ad9c783fd3c112054e5a7f439d6bf94 239 Gene3D G3DSA:3.40.50.300 3 239 1.0E-59 T 14-10-2018 LH59_25840 8ad9c783fd3c112054e5a7f439d6bf94 239 Pfam PF00005 ABC transporter 23 167 3.4E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_25840 8ad9c783fd3c112054e5a7f439d6bf94 239 SMART SM00382 32 216 1.5E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_15875 0a114eab5194835d5dd8ae620525b893 438 PRINTS PR00605 Class IC cytochrome C signature 385 407 3.3E-6 T 14-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 LH59_15875 0a114eab5194835d5dd8ae620525b893 438 PRINTS PR00605 Class IC cytochrome C signature 332 343 3.3E-6 T 14-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 LH59_15875 0a114eab5194835d5dd8ae620525b893 438 SUPERFAMILY SSF46626 25 154 2.76E-21 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_15875 0a114eab5194835d5dd8ae620525b893 438 Gene3D G3DSA:1.10.760.10 173 296 5.2E-10 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_15875 0a114eab5194835d5dd8ae620525b893 438 SUPERFAMILY SSF46626 325 428 6.77E-23 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_15875 0a114eab5194835d5dd8ae620525b893 438 SUPERFAMILY SSF46626 186 296 9.26E-20 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_15875 0a114eab5194835d5dd8ae620525b893 438 Gene3D G3DSA:1.10.760.10 305 436 4.4E-34 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_15875 0a114eab5194835d5dd8ae620525b893 438 Pfam PF00034 Cytochrome c 187 296 3.7E-4 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_15875 0a114eab5194835d5dd8ae620525b893 438 Pfam PF00034 Cytochrome c 35 132 1.7E-4 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_15875 0a114eab5194835d5dd8ae620525b893 438 Gene3D G3DSA:1.10.760.10 2 139 3.1E-11 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_15875 0a114eab5194835d5dd8ae620525b893 438 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 323 407 6.1E-9 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_15875 0a114eab5194835d5dd8ae620525b893 438 PIRSF PIRSF000018 1 437 2.6E-163 T 14-10-2018 IPR014353 Membrane-bound alcohol dehydrogenase, cytochrome c subunit GO:0005506|GO:0016020|GO:0016614|GO:0020037 LH59_22905 7df42f05b5c2108277a925e62b5abb34 364 Pfam PF06463 Molybdenum Cofactor Synthesis C 218 343 1.2E-35 T 14-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 LH59_22905 7df42f05b5c2108277a925e62b5abb34 364 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 28 364 5.0E-111 T 14-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 LH59_22905 7df42f05b5c2108277a925e62b5abb34 364 Pfam PF13353 4Fe-4S single cluster domain 44 143 9.4E-8 T 14-10-2018 LH59_22905 7df42f05b5c2108277a925e62b5abb34 364 SUPERFAMILY SSF102114 28 309 1.22E-71 T 14-10-2018 LH59_22905 7df42f05b5c2108277a925e62b5abb34 364 Pfam PF04055 Radical SAM superfamily 40 209 1.4E-27 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 LH59_22905 7df42f05b5c2108277a925e62b5abb34 364 SMART SM00729 36 250 5.4E-10 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 LH59_22905 7df42f05b5c2108277a925e62b5abb34 364 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 27 364 39.399 T 14-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 LH59_22905 7df42f05b5c2108277a925e62b5abb34 364 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 42 53 - T 14-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 LH59_22905 7df42f05b5c2108277a925e62b5abb34 364 Gene3D G3DSA:3.20.20.70 27 364 1.7E-90 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_14825 af2909c94ac7149e61eed74149bdf385 166 SUPERFAMILY SSF88946 5 96 5.49E-16 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 LH59_14825 af2909c94ac7149e61eed74149bdf385 166 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 6 158 1.1E-20 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 LH59_14825 af2909c94ac7149e61eed74149bdf385 166 Pfam PF04542 Sigma-70 region 2 8 76 7.4E-14 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 LH59_14825 af2909c94ac7149e61eed74149bdf385 166 Gene3D G3DSA:1.10.1740.10 2 73 2.3E-10 T 14-10-2018 LH59_14825 af2909c94ac7149e61eed74149bdf385 166 SUPERFAMILY SSF88659 101 161 1.96E-12 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like LH59_14825 af2909c94ac7149e61eed74149bdf385 166 Pfam PF08281 Sigma-70, region 4 107 159 2.6E-15 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LH59_14825 af2909c94ac7149e61eed74149bdf385 166 Gene3D G3DSA:1.10.10.10 82 163 1.5E-10 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_02940 cba7fb4f0e2c68c8dbb912459d324df4 263 Gene3D G3DSA:3.40.50.720 1 262 6.2E-84 T 14-10-2018 LH59_02940 cba7fb4f0e2c68c8dbb912459d324df4 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 2.1E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_02940 cba7fb4f0e2c68c8dbb912459d324df4 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 2.1E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_02940 cba7fb4f0e2c68c8dbb912459d324df4 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 2.1E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_02940 cba7fb4f0e2c68c8dbb912459d324df4 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.4E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_02940 cba7fb4f0e2c68c8dbb912459d324df4 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 1.4E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_02940 cba7fb4f0e2c68c8dbb912459d324df4 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.4E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_02940 cba7fb4f0e2c68c8dbb912459d324df4 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 1.4E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_02940 cba7fb4f0e2c68c8dbb912459d324df4 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.4E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_02940 cba7fb4f0e2c68c8dbb912459d324df4 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.4E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_02940 cba7fb4f0e2c68c8dbb912459d324df4 263 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LH59_02940 cba7fb4f0e2c68c8dbb912459d324df4 263 SUPERFAMILY SSF51735 6 262 4.76E-81 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_02940 cba7fb4f0e2c68c8dbb912459d324df4 263 Pfam PF00106 short chain dehydrogenase 12 199 2.9E-59 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_27915 21d2822f5ea1628a34d6d8705668527e 103 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 2.4E-18 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27915 21d2822f5ea1628a34d6d8705668527e 103 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 2.4E-18 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27915 21d2822f5ea1628a34d6d8705668527e 103 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 2.4E-18 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27915 21d2822f5ea1628a34d6d8705668527e 103 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 14-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27915 21d2822f5ea1628a34d6d8705668527e 103 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 6.5E-46 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27915 21d2822f5ea1628a34d6d8705668527e 103 Pfam PF00338 Ribosomal protein S10p/S20e 7 100 5.6E-36 T 14-10-2018 IPR027486 Ribosomal protein S10 domain LH59_27915 21d2822f5ea1628a34d6d8705668527e 103 SMART SM01403 7 101 1.8E-56 T 14-10-2018 IPR027486 Ribosomal protein S10 domain LH59_27915 21d2822f5ea1628a34d6d8705668527e 103 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 27.66 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27915 21d2822f5ea1628a34d6d8705668527e 103 Gene3D G3DSA:3.30.70.600 1 103 2.1E-37 T 14-10-2018 IPR036838 Ribosomal protein S10 domain superfamily LH59_27915 21d2822f5ea1628a34d6d8705668527e 103 SUPERFAMILY SSF54999 5 101 5.49E-38 T 14-10-2018 IPR036838 Ribosomal protein S10 domain superfamily LH59_09385 4659a161f580289b19a5e2faf8321c9a 1575 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 826 916 1.4E-26 T 14-10-2018 IPR010221 VCBS repeat LH59_09385 4659a161f580289b19a5e2faf8321c9a 1575 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 5 101 1.9E-32 T 14-10-2018 IPR010221 VCBS repeat LH59_09385 4659a161f580289b19a5e2faf8321c9a 1575 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 217 314 6.0E-33 T 14-10-2018 IPR010221 VCBS repeat LH59_09385 4659a161f580289b19a5e2faf8321c9a 1575 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 612 714 6.2E-28 T 14-10-2018 IPR010221 VCBS repeat LH59_09385 4659a161f580289b19a5e2faf8321c9a 1575 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 510 607 7.1E-33 T 14-10-2018 IPR010221 VCBS repeat LH59_09385 4659a161f580289b19a5e2faf8321c9a 1575 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 441 504 4.1E-10 T 14-10-2018 IPR010221 VCBS repeat LH59_09385 4659a161f580289b19a5e2faf8321c9a 1575 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 719 822 2.1E-28 T 14-10-2018 IPR010221 VCBS repeat LH59_09385 4659a161f580289b19a5e2faf8321c9a 1575 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 106 211 2.8E-26 T 14-10-2018 IPR010221 VCBS repeat LH59_09385 4659a161f580289b19a5e2faf8321c9a 1575 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 319 424 2.8E-26 T 14-10-2018 IPR010221 VCBS repeat LH59_09385 4659a161f580289b19a5e2faf8321c9a 1575 Gene3D G3DSA:2.150.10.10 1362 1421 6.8E-13 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal LH59_09385 4659a161f580289b19a5e2faf8321c9a 1575 SUPERFAMILY SSF51120 1377 1533 6.15E-33 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal LH59_09385 4659a161f580289b19a5e2faf8321c9a 1575 SMART SM00327 1064 1267 9.6E-18 T 14-10-2018 IPR002035 von Willebrand factor, type A LH59_09385 4659a161f580289b19a5e2faf8321c9a 1575 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 1434 1452 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site LH59_09385 4659a161f580289b19a5e2faf8321c9a 1575 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 1407 1425 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site LH59_09385 4659a161f580289b19a5e2faf8321c9a 1575 Pfam PF16184 Cadherin-like 897 999 3.1E-6 T 14-10-2018 LH59_09385 4659a161f580289b19a5e2faf8321c9a 1575 TIGRFAM TIGR03661 T1SS_VCA0849: type I secretion C-terminal target domain (VC_A0849 subclass) 1479 1570 6.5E-21 T 14-10-2018 IPR019960 Type I secretion C-terminal target domain, VC_A0849 subclass LH59_09385 4659a161f580289b19a5e2faf8321c9a 1575 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 1425 1443 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site LH59_09385 4659a161f580289b19a5e2faf8321c9a 1575 Gene3D G3DSA:3.40.50.410 1052 1257 1.5E-33 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily LH59_09385 4659a161f580289b19a5e2faf8321c9a 1575 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 1416 1434 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site LH59_09385 4659a161f580289b19a5e2faf8321c9a 1575 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1377 1391 0.3 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 LH59_09385 4659a161f580289b19a5e2faf8321c9a 1575 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1295 1308 0.15 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 LH59_09385 4659a161f580289b19a5e2faf8321c9a 1575 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1446 1463 0.0063 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 LH59_09385 4659a161f580289b19a5e2faf8321c9a 1575 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1410 1427 2.6E-4 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 LH59_09385 4659a161f580289b19a5e2faf8321c9a 1575 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1428 1445 0.0024 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 LH59_09385 4659a161f580289b19a5e2faf8321c9a 1575 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1392 1409 0.011 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 LH59_09385 4659a161f580289b19a5e2faf8321c9a 1575 Pfam PF00353 Haemolysin-type calcium-binding repeat (2 copies) 1040 1053 67.0 T 14-10-2018 IPR001343 Haemolysin-type calcium-binding repeat GO:0005509 LH59_09385 4659a161f580289b19a5e2faf8321c9a 1575 Gene3D G3DSA:2.150.10.10 1422 1551 7.5E-25 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal LH59_09385 4659a161f580289b19a5e2faf8321c9a 1575 SUPERFAMILY SSF53300 1053 1242 5.19E-24 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily LH59_09385 4659a161f580289b19a5e2faf8321c9a 1575 Pfam PF13519 von Willebrand factor type A domain 1068 1186 1.9E-14 T 14-10-2018 IPR002035 von Willebrand factor, type A LH59_09385 4659a161f580289b19a5e2faf8321c9a 1575 PRINTS PR00313 NodO calcium binding signature 1381 1392 1.2E-10 T 14-10-2018 LH59_09385 4659a161f580289b19a5e2faf8321c9a 1575 PRINTS PR00313 NodO calcium binding signature 1411 1419 1.2E-10 T 14-10-2018 LH59_09385 4659a161f580289b19a5e2faf8321c9a 1575 PRINTS PR00313 NodO calcium binding signature 1456 1465 1.2E-10 T 14-10-2018 LH59_09385 4659a161f580289b19a5e2faf8321c9a 1575 PRINTS PR00313 NodO calcium binding signature 1429 1437 1.2E-10 T 14-10-2018 LH59_17605 e60405dc1000e296d851adc726ccdb7a 273 Gene3D G3DSA:2.160.10.10 88 258 7.8E-57 T 14-10-2018 LH59_17605 e60405dc1000e296d851adc726ccdb7a 273 Hamap MF_00811 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 2 273 56.068 T 14-10-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 LH59_17605 e60405dc1000e296d851adc726ccdb7a 273 Gene3D G3DSA:1.10.166.10 3 71 1.2E-28 T 14-10-2018 IPR037133 Tetrahydrodipicolinate-N-succinyltransferase, N-terminal domain superfamily KEGG: 00300+2.3.1.117 LH59_17605 e60405dc1000e296d851adc726ccdb7a 273 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 135 163 - T 14-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 LH59_17605 e60405dc1000e296d851adc726ccdb7a 273 TIGRFAM TIGR00965 dapD: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 5 272 5.7E-140 T 14-10-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 LH59_17605 e60405dc1000e296d851adc726ccdb7a 273 SUPERFAMILY SSF51161 3 257 3.05E-76 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily LH59_17605 e60405dc1000e296d851adc726ccdb7a 273 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 116 167 6.1E-4 T 14-10-2018 IPR001451 Hexapeptide repeat LH59_17605 e60405dc1000e296d851adc726ccdb7a 273 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 176 210 1.1E-13 T 14-10-2018 IPR001451 Hexapeptide repeat LH59_17605 e60405dc1000e296d851adc726ccdb7a 273 Pfam PF14805 Tetrahydrodipicolinate N-succinyltransferase N-terminal 4 70 2.3E-26 T 14-10-2018 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117 LH59_01840 beeb1b413ce094f3f0a6a63e0c20f9d0 239 SUPERFAMILY SSF51366 13 229 4.95E-72 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 LH59_01840 beeb1b413ce094f3f0a6a63e0c20f9d0 239 Gene3D G3DSA:3.20.20.70 8 235 2.8E-79 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_01840 beeb1b413ce094f3f0a6a63e0c20f9d0 239 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 15 228 1.8E-93 T 14-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 LH59_01840 beeb1b413ce094f3f0a6a63e0c20f9d0 239 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 144 166 - T 14-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 LH59_01840 beeb1b413ce094f3f0a6a63e0c20f9d0 239 PIRSF PIRSF001461 9 238 3.9E-101 T 14-10-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 LH59_01840 beeb1b413ce094f3f0a6a63e0c20f9d0 239 Pfam PF00834 Ribulose-phosphate 3 epimerase family 15 215 7.8E-87 T 14-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 LH59_01840 beeb1b413ce094f3f0a6a63e0c20f9d0 239 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 42 56 - T 14-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 LH59_02860 9d6c521ead5009a108fca31536ab8caa 320 Pfam PF02581 Thiamine monophosphate synthase 148 318 4.6E-38 T 14-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 LH59_02860 9d6c521ead5009a108fca31536ab8caa 320 Pfam PF00293 NUDIX domain 9 114 5.4E-19 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 LH59_02860 9d6c521ead5009a108fca31536ab8caa 320 ProSitePatterns PS00893 Nudix box signature. 40 61 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 LH59_02860 9d6c521ead5009a108fca31536ab8caa 320 SUPERFAMILY SSF55811 6 116 1.34E-34 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 LH59_02860 9d6c521ead5009a108fca31536ab8caa 320 Gene3D G3DSA:3.90.79.10 1 131 3.4E-34 T 14-10-2018 LH59_02860 9d6c521ead5009a108fca31536ab8caa 320 Gene3D G3DSA:3.20.20.70 134 320 1.9E-42 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_02860 9d6c521ead5009a108fca31536ab8caa 320 SUPERFAMILY SSF51391 118 319 9.68E-43 T 14-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 LH59_02860 9d6c521ead5009a108fca31536ab8caa 320 PRINTS PR00502 NUDIX hydrolase family signature 35 49 9.3E-8 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 LH59_02860 9d6c521ead5009a108fca31536ab8caa 320 PRINTS PR00502 NUDIX hydrolase family signature 49 64 9.3E-8 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 LH59_14485 c73ecf81c87e33effd474b95b5f1a341 144 Pfam PF02036 SCP-2 sterol transfer family 47 126 5.4E-9 T 14-10-2018 IPR003033 SCP2 sterol-binding domain LH59_14485 c73ecf81c87e33effd474b95b5f1a341 144 SUPERFAMILY SSF55718 34 131 1.46E-15 T 14-10-2018 IPR036527 SCP2 sterol-binding domain superfamily LH59_04555 93281c0deb284fa4a1a16b5de99ef3d3 160 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 7 135 6.8E-39 T 14-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 LH59_04555 93281c0deb284fa4a1a16b5de99ef3d3 160 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 90 101 - T 14-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 LH59_04555 93281c0deb284fa4a1a16b5de99ef3d3 160 Gene3D G3DSA:3.30.70.560 5 159 1.7E-47 T 14-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 LH59_04555 93281c0deb284fa4a1a16b5de99ef3d3 160 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 8 135 4.1E-34 T 14-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 LH59_04555 93281c0deb284fa4a1a16b5de99ef3d3 160 SUPERFAMILY SSF55083 6 145 4.45E-47 T 14-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 LH59_18190 23d0f8ee811d3f7a5bb098c578816b0b 868 SUPERFAMILY SSF52540 555 864 3.01E-83 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_18190 23d0f8ee811d3f7a5bb098c578816b0b 868 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 94 144 5.5E-12 T 14-10-2018 IPR004176 Clp, N-terminal LH59_18190 23d0f8ee811d3f7a5bb098c578816b0b 868 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 68 2.8E-12 T 14-10-2018 IPR004176 Clp, N-terminal LH59_18190 23d0f8ee811d3f7a5bb098c578816b0b 868 Gene3D G3DSA:3.40.50.300 342 553 1.2E-68 T 14-10-2018 LH59_18190 23d0f8ee811d3f7a5bb098c578816b0b 868 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 610 628 2.3E-42 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 LH59_18190 23d0f8ee811d3f7a5bb098c578816b0b 868 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 717 731 2.3E-42 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 LH59_18190 23d0f8ee811d3f7a5bb098c578816b0b 868 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 655 673 2.3E-42 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 LH59_18190 23d0f8ee811d3f7a5bb098c578816b0b 868 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 684 702 2.3E-42 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 LH59_18190 23d0f8ee811d3f7a5bb098c578816b0b 868 Gene3D G3DSA:1.10.1780.10 1 147 1.7E-35 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 LH59_18190 23d0f8ee811d3f7a5bb098c578816b0b 868 SMART SM01086 774 863 2.4E-35 T 14-10-2018 IPR019489 Clp ATPase, C-terminal LH59_18190 23d0f8ee811d3f7a5bb098c578816b0b 868 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 640 658 - T 14-10-2018 IPR028299 ClpA/B, conserved site 2 LH59_18190 23d0f8ee811d3f7a5bb098c578816b0b 868 SMART SM00382 606 775 4.7E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_18190 23d0f8ee811d3f7a5bb098c578816b0b 868 SMART SM00382 197 343 6.4E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_18190 23d0f8ee811d3f7a5bb098c578816b0b 868 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 293 305 - T 14-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 LH59_18190 23d0f8ee811d3f7a5bb098c578816b0b 868 SUPERFAMILY SSF81923 4 140 2.75E-37 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 LH59_18190 23d0f8ee811d3f7a5bb098c578816b0b 868 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 863 0.0 T 14-10-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0042026 LH59_18190 23d0f8ee811d3f7a5bb098c578816b0b 868 Gene3D G3DSA:3.40.50.300 559 772 8.4E-87 T 14-10-2018 LH59_18190 23d0f8ee811d3f7a5bb098c578816b0b 868 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 202 334 9.4E-13 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 LH59_18190 23d0f8ee811d3f7a5bb098c578816b0b 868 SUPERFAMILY SSF52540 158 519 2.35E-98 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_18190 23d0f8ee811d3f7a5bb098c578816b0b 868 Pfam PF07724 AAA domain (Cdc48 subfamily) 605 768 1.1E-55 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 LH59_18190 23d0f8ee811d3f7a5bb098c578816b0b 868 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 774 852 6.7E-25 T 14-10-2018 IPR019489 Clp ATPase, C-terminal LH59_18190 23d0f8ee811d3f7a5bb098c578816b0b 868 Gene3D G3DSA:1.10.8.60 774 867 2.3E-27 T 14-10-2018 LH59_18190 23d0f8ee811d3f7a5bb098c578816b0b 868 Gene3D G3DSA:3.40.50.300 148 341 2.0E-73 T 14-10-2018 LH59_00280 3eb2e1a148983bba5eeede81c5dde192 225 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 69 4.3E-17 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_00280 3eb2e1a148983bba5eeede81c5dde192 225 Gene3D G3DSA:1.10.357.10 17 206 1.0E-47 T 14-10-2018 LH59_00280 3eb2e1a148983bba5eeede81c5dde192 225 SUPERFAMILY SSF46689 9 89 5.82E-21 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_00280 3eb2e1a148983bba5eeede81c5dde192 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 2.5E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_00280 3eb2e1a148983bba5eeede81c5dde192 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 2.5E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_18090 fda516dbcb26390abefd82b06791a992 249 Gene3D G3DSA:3.90.850.10 39 246 2.6E-74 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 LH59_18090 fda516dbcb26390abefd82b06791a992 249 SUPERFAMILY SSF56529 36 245 2.09E-74 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 LH59_18090 fda516dbcb26390abefd82b06791a992 249 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 48 244 3.1E-61 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 LH59_18090 fda516dbcb26390abefd82b06791a992 249 TIGRFAM TIGR02303 HpaG-C-term: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit 2 245 1.8E-114 T 14-10-2018 IPR012684 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit GO:0008704|GO:0018800|GO:1901023 KEGG: 00350+5.3.3.10+4.1.1.68 LH59_25775 0be1dbee878745b55a3da06c65f2b6c8 397 Gene3D G3DSA:2.40.30.170 60 307 1.7E-93 T 14-10-2018 LH59_25775 0be1dbee878745b55a3da06c65f2b6c8 397 Gene3D G3DSA:2.40.50.100 71 216 1.7E-93 T 14-10-2018 LH59_25775 0be1dbee878745b55a3da06c65f2b6c8 397 Gene3D G3DSA:2.40.420.20 308 376 1.7E-93 T 14-10-2018 LH59_25775 0be1dbee878745b55a3da06c65f2b6c8 397 SUPERFAMILY SSF111369 62 301 2.88E-62 T 14-10-2018 LH59_25775 0be1dbee878745b55a3da06c65f2b6c8 397 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 73 297 2.2E-14 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain LH59_25775 0be1dbee878745b55a3da06c65f2b6c8 397 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 47 378 4.3E-87 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 LH59_25775 0be1dbee878745b55a3da06c65f2b6c8 397 Gene3D G3DSA:1.10.287.470 106 179 1.7E-93 T 14-10-2018 LH59_02960 19eb4c399b5ccb1e4d77cad30478f5df 141 Pfam PF13279 Thioesterase-like superfamily 11 132 2.3E-7 T 14-10-2018 LH59_02960 19eb4c399b5ccb1e4d77cad30478f5df 141 Gene3D G3DSA:3.10.129.10 1 139 7.5E-37 T 14-10-2018 LH59_02960 19eb4c399b5ccb1e4d77cad30478f5df 141 SUPERFAMILY SSF54637 2 137 4.48E-38 T 14-10-2018 IPR029069 HotDog domain superfamily LH59_16955 64b4852cbe5257524c1fcf53b2c22da5 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 4.0E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_16955 64b4852cbe5257524c1fcf53b2c22da5 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 4.0E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_16955 64b4852cbe5257524c1fcf53b2c22da5 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 4.0E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_16955 64b4852cbe5257524c1fcf53b2c22da5 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 4.0E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_16955 64b4852cbe5257524c1fcf53b2c22da5 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 4.0E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_16955 64b4852cbe5257524c1fcf53b2c22da5 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 4.0E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_16955 64b4852cbe5257524c1fcf53b2c22da5 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 252 3.1E-56 T 14-10-2018 LH59_16955 64b4852cbe5257524c1fcf53b2c22da5 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 1.8E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_16955 64b4852cbe5257524c1fcf53b2c22da5 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.8E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_16955 64b4852cbe5257524c1fcf53b2c22da5 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 1.8E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_16955 64b4852cbe5257524c1fcf53b2c22da5 253 Gene3D G3DSA:3.40.50.720 1 253 5.0E-79 T 14-10-2018 LH59_16955 64b4852cbe5257524c1fcf53b2c22da5 253 SUPERFAMILY SSF51735 9 252 1.9E-74 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_16955 64b4852cbe5257524c1fcf53b2c22da5 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 149 177 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LH59_07795 761343754ee308e1338d891f37b1f91f 620 SUPERFAMILY SSF52518 291 474 5.15E-57 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold LH59_07795 761343754ee308e1338d891f37b1f91f 620 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 8 613 6.8E-260 T 14-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 LH59_07795 761343754ee308e1338d891f37b1f91f 620 Pfam PF02780 Transketolase, C-terminal domain 491 607 1.0E-26 T 14-10-2018 IPR033248 Transketolase, C-terminal domain LH59_07795 761343754ee308e1338d891f37b1f91f 620 Gene3D G3DSA:3.40.50.970 313 483 1.1E-63 T 14-10-2018 LH59_07795 761343754ee308e1338d891f37b1f91f 620 Pfam PF02779 Transketolase, pyrimidine binding domain 316 474 2.7E-37 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain LH59_07795 761343754ee308e1338d891f37b1f91f 620 SUPERFAMILY SSF52518 3 345 1.62E-76 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold LH59_07795 761343754ee308e1338d891f37b1f91f 620 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 6 278 4.1E-120 T 14-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 LH59_07795 761343754ee308e1338d891f37b1f91f 620 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 5 616 45.546 T 14-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 LH59_07795 761343754ee308e1338d891f37b1f91f 620 ProSitePatterns PS00802 Transketolase signature 2. 421 437 - T 14-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 LH59_07795 761343754ee308e1338d891f37b1f91f 620 ProSitePatterns PS00801 Transketolase signature 1. 31 50 - T 14-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 LH59_07795 761343754ee308e1338d891f37b1f91f 620 Gene3D G3DSA:3.40.50.920 491 616 2.2E-43 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 LH59_07795 761343754ee308e1338d891f37b1f91f 620 SMART SM00861 315 479 2.7E-59 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain LH59_07795 761343754ee308e1338d891f37b1f91f 620 SUPERFAMILY SSF52922 487 613 7.46E-33 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 LH59_02455 dbe5b2df9cd2a4a5a2a49c68547c220a 597 Gene3D G3DSA:2.60.40.420 33 166 6.3E-40 T 14-10-2018 IPR008972 Cupredoxin LH59_02455 dbe5b2df9cd2a4a5a2a49c68547c220a 597 Gene3D G3DSA:2.60.40.420 175 381 6.7E-42 T 14-10-2018 IPR008972 Cupredoxin LH59_02455 dbe5b2df9cd2a4a5a2a49c68547c220a 597 Pfam PF07732 Multicopper oxidase 57 167 3.9E-41 T 14-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 LH59_02455 dbe5b2df9cd2a4a5a2a49c68547c220a 597 ProSitePatterns PS00080 Multicopper oxidases signature 2. 579 590 - T 14-10-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 LH59_02455 dbe5b2df9cd2a4a5a2a49c68547c220a 597 Pfam PF07731 Multicopper oxidase 480 596 2.7E-26 T 14-10-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 LH59_02455 dbe5b2df9cd2a4a5a2a49c68547c220a 597 SUPERFAMILY SSF49503 51 197 4.68E-40 T 14-10-2018 IPR008972 Cupredoxin LH59_02455 dbe5b2df9cd2a4a5a2a49c68547c220a 597 TIGRFAM TIGR01480 copper_res_A: copper-resistance protein, CopA family 8 597 1.3E-286 T 14-10-2018 IPR006376 Copper-resistance protein CopA GO:0005507|GO:0042597 LH59_02455 dbe5b2df9cd2a4a5a2a49c68547c220a 597 ProSitePatterns PS00079 Multicopper oxidases signature 1. 142 162 - T 14-10-2018 IPR033138 Multicopper oxidases, conserved site LH59_02455 dbe5b2df9cd2a4a5a2a49c68547c220a 597 Gene3D G3DSA:2.60.40.420 466 597 5.9E-32 T 14-10-2018 IPR008972 Cupredoxin LH59_02455 dbe5b2df9cd2a4a5a2a49c68547c220a 597 Pfam PF00394 Multicopper oxidase 177 352 7.3E-32 T 14-10-2018 IPR001117 Multicopper oxidase, type 1 GO:0055114 LH59_02455 dbe5b2df9cd2a4a5a2a49c68547c220a 597 ProSitePatterns PS00079 Multicopper oxidases signature 1. 574 594 - T 14-10-2018 IPR033138 Multicopper oxidases, conserved site LH59_02455 dbe5b2df9cd2a4a5a2a49c68547c220a 597 SUPERFAMILY SSF49503 171 378 4.07E-55 T 14-10-2018 IPR008972 Cupredoxin LH59_02455 dbe5b2df9cd2a4a5a2a49c68547c220a 597 SUPERFAMILY SSF49503 447 596 7.85E-40 T 14-10-2018 IPR008972 Cupredoxin LH59_18590 472db18c00444d4116c9cec56b8f4329 337 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 195 293 5.1E-20 T 14-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 LH59_18590 472db18c00444d4116c9cec56b8f4329 337 Gene3D G3DSA:3.40.50.720 2 197 6.4E-48 T 14-10-2018 LH59_18590 472db18c00444d4116c9cec56b8f4329 337 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 5 190 8.3E-45 T 14-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 LH59_18590 472db18c00444d4116c9cec56b8f4329 337 SUPERFAMILY SSF51735 3 191 5.97E-41 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_18590 472db18c00444d4116c9cec56b8f4329 337 SUPERFAMILY SSF48179 195 293 5.1E-23 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 LH59_18590 472db18c00444d4116c9cec56b8f4329 337 Gene3D G3DSA:1.10.1040.10 198 317 2.9E-31 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 LH59_18590 472db18c00444d4116c9cec56b8f4329 337 PIRSF PIRSF000105 1 322 1.4E-77 T 14-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 LH59_12425 64f7ddae768d590f3ef09d4237fd69f6 296 SUPERFAMILY SSF53335 9 282 8.86E-93 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_12425 64f7ddae768d590f3ef09d4237fd69f6 296 Pfam PF04378 Ribosomal RNA large subunit methyltransferase D, RlmJ 33 281 8.3E-73 T 14-10-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 LH59_12425 64f7ddae768d590f3ef09d4237fd69f6 296 Hamap MF_00934 Ribosomal RNA large subunit methyltransferase J [rlmJ]. 2 272 39.903 T 14-10-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 LH59_12425 64f7ddae768d590f3ef09d4237fd69f6 296 Gene3D G3DSA:3.40.50.150 1 288 4.1E-107 T 14-10-2018 LH59_13695 cc5fb39b9bccb0bd09a0ba3b05ae6716 408 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 172 5.6E-11 T 14-10-2018 LH59_13695 cc5fb39b9bccb0bd09a0ba3b05ae6716 408 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 5.6E-11 T 14-10-2018 LH59_13695 cc5fb39b9bccb0bd09a0ba3b05ae6716 408 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 234 248 5.6E-11 T 14-10-2018 LH59_13695 cc5fb39b9bccb0bd09a0ba3b05ae6716 408 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 273 280 5.6E-11 T 14-10-2018 LH59_13695 cc5fb39b9bccb0bd09a0ba3b05ae6716 408 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 302 2.3E-59 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LH59_13695 cc5fb39b9bccb0bd09a0ba3b05ae6716 408 Gene3D G3DSA:3.50.50.60 6 307 3.0E-101 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_13695 cc5fb39b9bccb0bd09a0ba3b05ae6716 408 Gene3D G3DSA:3.50.50.60 115 240 3.0E-101 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_13695 cc5fb39b9bccb0bd09a0ba3b05ae6716 408 Pfam PF14759 Reductase C-terminal 322 404 4.7E-19 T 14-10-2018 IPR028202 Reductase, C-terminal LH59_13695 cc5fb39b9bccb0bd09a0ba3b05ae6716 408 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 233 249 1.2E-20 T 14-10-2018 LH59_13695 cc5fb39b9bccb0bd09a0ba3b05ae6716 408 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.2E-20 T 14-10-2018 LH59_13695 cc5fb39b9bccb0bd09a0ba3b05ae6716 408 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 1.2E-20 T 14-10-2018 LH59_13695 cc5fb39b9bccb0bd09a0ba3b05ae6716 408 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 280 1.2E-20 T 14-10-2018 LH59_13695 cc5fb39b9bccb0bd09a0ba3b05ae6716 408 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 1.2E-20 T 14-10-2018 LH59_13695 cc5fb39b9bccb0bd09a0ba3b05ae6716 408 SUPERFAMILY SSF55424 315 404 5.77E-17 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 LH59_13695 cc5fb39b9bccb0bd09a0ba3b05ae6716 408 Gene3D G3DSA:3.30.390.30 322 407 1.2E-16 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 LH59_13695 cc5fb39b9bccb0bd09a0ba3b05ae6716 408 SUPERFAMILY SSF51905 146 308 4.53E-26 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_13695 cc5fb39b9bccb0bd09a0ba3b05ae6716 408 SUPERFAMILY SSF51905 6 192 3.78E-46 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_09235 87b3753aee11b19033eeac8759964f35 687 SMART SM00493 256 327 1.7E-18 T 14-10-2018 IPR006171 TOPRIM domain LH59_09235 87b3753aee11b19033eeac8759964f35 687 Gene3D G3DSA:3.90.980.10 110 237 6.2E-37 T 14-10-2018 IPR037068 DNA primase, catalytic core, N-terminal domain superfamily LH59_09235 87b3753aee11b19033eeac8759964f35 687 SUPERFAMILY SSF117023 549 676 3.01E-13 T 14-10-2018 LH59_09235 87b3753aee11b19033eeac8759964f35 687 SUPERFAMILY SSF56731 119 419 3.14E-100 T 14-10-2018 LH59_09235 87b3753aee11b19033eeac8759964f35 687 TIGRFAM TIGR01391 dnaG: DNA primase 2 414 1.4E-137 T 14-10-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 LH59_09235 87b3753aee11b19033eeac8759964f35 687 Gene3D G3DSA:3.40.1360.10 238 364 9.5E-42 T 14-10-2018 LH59_09235 87b3753aee11b19033eeac8759964f35 687 Pfam PF08278 DNA primase DnaG DnaB-binding 553 674 3.8E-14 T 14-10-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 LH59_09235 87b3753aee11b19033eeac8759964f35 687 Pfam PF10410 DnaB-helicase binding domain of primase 366 421 2.2E-9 T 14-10-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 LH59_09235 87b3753aee11b19033eeac8759964f35 687 SMART SM00400 33 87 4.2E-34 T 14-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 LH59_09235 87b3753aee11b19033eeac8759964f35 687 Hamap MF_00974 DNA primase [dnaG]. 1 679 27.219 T 14-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 LH59_09235 87b3753aee11b19033eeac8759964f35 687 Pfam PF13662 Toprim domain 257 322 6.7E-16 T 14-10-2018 IPR006171 TOPRIM domain LH59_09235 87b3753aee11b19033eeac8759964f35 687 SUPERFAMILY SSF57783 2 97 4.42E-36 T 14-10-2018 LH59_09235 87b3753aee11b19033eeac8759964f35 687 Gene3D G3DSA:3.90.580.10 1 99 9.8E-39 T 14-10-2018 IPR036977 DNA Primase, CHC2-type zinc finger GO:0003677|GO:0006260|GO:0008270 LH59_09235 87b3753aee11b19033eeac8759964f35 687 Pfam PF01807 CHC2 zinc finger 3 97 3.6E-37 T 14-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 LH59_09235 87b3753aee11b19033eeac8759964f35 687 SMART SM00766 551 675 2.5E-21 T 14-10-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 LH59_09235 87b3753aee11b19033eeac8759964f35 687 Pfam PF08275 DNA primase catalytic core, N-terminal domain 129 248 4.8E-36 T 14-10-2018 IPR013264 DNA primase, catalytic core, N-terminal LH59_04180 2b0c4a4e416eb87e02f56f19ee0f6b75 741 Gene3D G3DSA:3.20.20.80 233 609 7.8E-76 T 14-10-2018 LH59_04180 2b0c4a4e416eb87e02f56f19ee0f6b75 741 SUPERFAMILY SSF74650 12 233 5.02E-27 T 14-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 LH59_04180 2b0c4a4e416eb87e02f56f19ee0f6b75 741 Gene3D G3DSA:2.60.40.1760 11 232 3.0E-20 T 14-10-2018 LH59_04180 2b0c4a4e416eb87e02f56f19ee0f6b75 741 SUPERFAMILY SSF51445 236 577 9.27E-41 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily LH59_04180 2b0c4a4e416eb87e02f56f19ee0f6b75 741 Pfam PF01055 Glycosyl hydrolases family 31 228 663 1.2E-75 T 14-10-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 LH59_04180 2b0c4a4e416eb87e02f56f19ee0f6b75 741 SUPERFAMILY SSF51011 579 658 1.08E-19 T 14-10-2018 LH59_04180 2b0c4a4e416eb87e02f56f19ee0f6b75 741 Gene3D G3DSA:2.60.40.1180 610 658 2.9E-9 T 14-10-2018 IPR013780 Glycosyl hydrolase, all-beta LH59_12135 3e7eb467390cc02a807a57f3525ce6c4 166 SMART SM00342 40 123 1.8E-26 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_12135 3e7eb467390cc02a807a57f3525ce6c4 166 Gene3D G3DSA:1.10.10.60 75 127 3.6E-14 T 14-10-2018 LH59_12135 3e7eb467390cc02a807a57f3525ce6c4 166 Pfam PF12833 Helix-turn-helix domain 46 123 5.2E-23 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_12135 3e7eb467390cc02a807a57f3525ce6c4 166 SUPERFAMILY SSF46689 76 125 4.93E-12 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_12135 3e7eb467390cc02a807a57f3525ce6c4 166 SUPERFAMILY SSF46689 24 73 4.96E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_12135 3e7eb467390cc02a807a57f3525ce6c4 166 Gene3D G3DSA:1.10.10.60 22 74 2.0E-9 T 14-10-2018 LH59_06385 228e316af4849a91322ae7c1c7956ccd 391 TIGRFAM TIGR01514 NAPRTase: nicotinate phosphoribosyltransferase 2 389 2.4E-146 T 14-10-2018 IPR006406 Nicotinate phosphoribosyltransferase GO:0004516|GO:0019357 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 LH59_06385 228e316af4849a91322ae7c1c7956ccd 391 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 163 388 5.7E-71 T 14-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 LH59_06385 228e316af4849a91322ae7c1c7956ccd 391 SUPERFAMILY SSF54675 1 136 8.05E-44 T 14-10-2018 LH59_06385 228e316af4849a91322ae7c1c7956ccd 391 Hamap MF_00570 Nicotinate phosphoribosyltransferase [pncB]. 1 390 45.925 T 14-10-2018 IPR006406 Nicotinate phosphoribosyltransferase GO:0004516|GO:0019357 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 LH59_06385 228e316af4849a91322ae7c1c7956ccd 391 Gene3D G3DSA:3.20.140.10 1 390 2.9E-150 T 14-10-2018 LH59_06385 228e316af4849a91322ae7c1c7956ccd 391 SUPERFAMILY SSF51690 117 387 5.1E-88 T 14-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 LH59_06385 228e316af4849a91322ae7c1c7956ccd 391 PIRSF PIRSF000484 1 376 7.3E-68 T 14-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 LH59_22370 6991427e1ec8ec908adfec30c8e2c12c 397 Pfam PF01979 Amidohydrolase family 52 358 2.4E-13 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 LH59_22370 6991427e1ec8ec908adfec30c8e2c12c 397 Gene3D G3DSA:2.30.40.10 309 379 8.5E-8 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 LH59_22370 6991427e1ec8ec908adfec30c8e2c12c 397 SUPERFAMILY SSF51338 2 378 4.86E-17 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 LH59_22370 6991427e1ec8ec908adfec30c8e2c12c 397 Gene3D G3DSA:3.20.20.140 53 223 7.9E-14 T 14-10-2018 LH59_22370 6991427e1ec8ec908adfec30c8e2c12c 397 TIGRFAM TIGR02318 phosphono_phnM: phosphonate metabolism protein PhnM 6 377 2.5E-120 T 14-10-2018 IPR012696 Phosphonate metabolism PhnM GO:0019700 KEGG: 00440+3.6.1.63|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 LH59_22370 6991427e1ec8ec908adfec30c8e2c12c 397 SUPERFAMILY SSF51556 54 343 1.76E-17 T 14-10-2018 IPR032466 Metal-dependent hydrolase LH59_22370 6991427e1ec8ec908adfec30c8e2c12c 397 PIRSF PIRSF038971 2 377 1.3E-113 T 14-10-2018 IPR012696 Phosphonate metabolism PhnM GO:0019700 KEGG: 00440+3.6.1.63|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 LH59_22370 6991427e1ec8ec908adfec30c8e2c12c 397 Gene3D G3DSA:2.30.40.10 8 52 7.9E-14 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 LH59_16040 6386b3b3db1026dc0048a7736e8fc74b 327 Pfam PF08908 Domain of unknown function (DUF1852) 1 323 2.1E-187 T 14-10-2018 IPR015004 Protein of unknown function DUF1852 LH59_16040 6386b3b3db1026dc0048a7736e8fc74b 327 PIRSF PIRSF034367 1 327 1.3E-196 T 14-10-2018 IPR015004 Protein of unknown function DUF1852 LH59_05375 6a7decad4c2d6db7dedc7decb8022b95 418 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 305 324 - T 14-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 LH59_05375 6a7decad4c2d6db7dedc7decb8022b95 418 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 31 412 1.2E-111 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 LH59_05375 6a7decad4c2d6db7dedc7decb8022b95 418 Gene3D G3DSA:3.40.718.10 1 418 1.5E-183 T 14-10-2018 LH59_05375 6a7decad4c2d6db7dedc7decb8022b95 418 SUPERFAMILY SSF53659 4 418 1.52E-140 T 14-10-2018 LH59_05375 6a7decad4c2d6db7dedc7decb8022b95 418 TIGRFAM TIGR00183 prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent 3 418 4.9E-217 T 14-10-2018 IPR004439 Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 LH59_05375 6a7decad4c2d6db7dedc7decb8022b95 418 SMART SM01329 30 414 1.5E-163 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 LH59_18615 544fb9ef893fe2ec9ddb045b8b588fe0 484 Gene3D G3DSA:3.40.640.10 119 473 4.2E-110 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_18615 544fb9ef893fe2ec9ddb045b8b588fe0 484 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 77 1.4E-12 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_18615 544fb9ef893fe2ec9ddb045b8b588fe0 484 SUPERFAMILY SSF53383 132 480 5.18E-74 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_18615 544fb9ef893fe2ec9ddb045b8b588fe0 484 Gene3D G3DSA:1.10.10.10 10 81 2.7E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_18615 544fb9ef893fe2ec9ddb045b8b588fe0 484 SMART SM00345 18 77 1.1E-12 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_18615 544fb9ef893fe2ec9ddb045b8b588fe0 484 SUPERFAMILY SSF46785 10 80 1.25E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_18615 544fb9ef893fe2ec9ddb045b8b588fe0 484 Pfam PF00155 Aminotransferase class I and II 161 416 3.0E-14 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LH59_28060 cdf9500e0f12dfe054a77c3003a82ef5 335 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_28060 cdf9500e0f12dfe054a77c3003a82ef5 335 SUPERFAMILY SSF52540 3 242 1.86E-85 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_28060 cdf9500e0f12dfe054a77c3003a82ef5 335 SMART SM00382 27 210 4.2E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_28060 cdf9500e0f12dfe054a77c3003a82ef5 335 Pfam PF08402 TOBE domain 266 331 1.3E-11 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 LH59_28060 cdf9500e0f12dfe054a77c3003a82ef5 335 Pfam PF00005 ABC transporter 18 160 3.7E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_28060 cdf9500e0f12dfe054a77c3003a82ef5 335 SUPERFAMILY SSF50331 258 331 1.67E-8 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal LH59_28060 cdf9500e0f12dfe054a77c3003a82ef5 335 Gene3D G3DSA:3.40.50.300 1 236 1.7E-76 T 14-10-2018 LH59_10100 5f6854a33446b7c6d97ae0d8dd838beb 330 SUPERFAMILY SSF50475 177 290 7.62E-11 T 14-10-2018 LH59_10100 5f6854a33446b7c6d97ae0d8dd838beb 330 Gene3D G3DSA:2.30.110.10 179 303 9.7E-16 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 LH59_10100 5f6854a33446b7c6d97ae0d8dd838beb 330 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 183 274 1.3E-13 T 14-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 LH59_03090 456cc90a4e4391bf1f1afd7e971beca0 238 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 40 222 4.3E-19 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_03090 456cc90a4e4391bf1f1afd7e971beca0 238 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 24 116 1.2E-22 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 LH59_03090 456cc90a4e4391bf1f1afd7e971beca0 238 SUPERFAMILY SSF161098 22 208 3.27E-43 T 14-10-2018 IPR035906 MetI-like superfamily LH59_03090 456cc90a4e4391bf1f1afd7e971beca0 238 Gene3D G3DSA:1.10.3720.10 19 224 3.6E-50 T 14-10-2018 IPR035906 MetI-like superfamily LH59_24780 4b3afdda8826d1f150731111c9ba8d82 313 SUPERFAMILY SSF161098 92 297 7.06E-18 T 14-10-2018 IPR035906 MetI-like superfamily LH59_24780 4b3afdda8826d1f150731111c9ba8d82 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 313 2.5E-40 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_24780 4b3afdda8826d1f150731111c9ba8d82 313 Gene3D G3DSA:1.10.3720.10 84 305 1.0E-22 T 14-10-2018 IPR035906 MetI-like superfamily LH59_14375 c9bb060df61672ea8f98710755ab6e75 374 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 104 129 - T 14-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 LH59_14375 c9bb060df61672ea8f98710755ab6e75 374 Gene3D G3DSA:3.30.390.10 32 368 1.7E-122 T 14-10-2018 IPR029017 Enolase-like, N-terminal LH59_14375 c9bb060df61672ea8f98710755ab6e75 374 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 195 226 - T 14-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 LH59_14375 c9bb060df61672ea8f98710755ab6e75 374 SUPERFAMILY SSF54826 5 130 1.62E-31 T 14-10-2018 LH59_14375 c9bb060df61672ea8f98710755ab6e75 374 Gene3D G3DSA:3.20.20.120 122 357 1.7E-122 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily LH59_14375 c9bb060df61672ea8f98710755ab6e75 374 SUPERFAMILY SSF51604 117 373 2.36E-65 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily LH59_14375 c9bb060df61672ea8f98710755ab6e75 374 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 11 129 7.1E-31 T 14-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain LH59_14375 c9bb060df61672ea8f98710755ab6e75 374 TIGRFAM TIGR02534 mucon_cyclo: muconate and chloromuconate cycloisomerases 6 373 9.3E-172 T 14-10-2018 IPR013370 Muconate/chloromuconate cycloisomerase GO:0018849|GO:0018850|GO:0030145 LH59_14375 c9bb060df61672ea8f98710755ab6e75 374 Pfam PF13378 Enolase C-terminal domain-like 152 365 1.1E-49 T 14-10-2018 IPR029065 Enolase C-terminal domain-like LH59_14375 c9bb060df61672ea8f98710755ab6e75 374 SMART SM00922 147 245 3.5E-19 T 14-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal LH59_01005 bb2f1ee3694fbbac33121c1c55be1683 166 Pfam PF02470 MlaD protein 39 116 2.6E-22 T 14-10-2018 IPR003399 Mce/MlaD LH59_01005 bb2f1ee3694fbbac33121c1c55be1683 166 TIGRFAM TIGR04430 OM_asym_MlaD: outer membrane lipid asymmetry maintenance protein MlaD 3 146 1.2E-59 T 14-10-2018 IPR030970 Probable phospholipid ABC transporter-binding protein MlaD GO:0015914 LH59_05975 01e4ca52a88f4833cb604715cace8804 519 SUPERFAMILY SSF53850 21 504 3.39E-115 T 14-10-2018 LH59_05975 01e4ca52a88f4833cb604715cace8804 519 Gene3D G3DSA:3.90.76.10 40 189 1.5E-111 T 14-10-2018 LH59_05975 01e4ca52a88f4833cb604715cace8804 519 Gene3D G3DSA:3.10.105.10 283 494 1.5E-111 T 14-10-2018 LH59_05975 01e4ca52a88f4833cb604715cace8804 519 Gene3D G3DSA:3.40.190.10 190 503 1.5E-111 T 14-10-2018 LH59_05975 01e4ca52a88f4833cb604715cace8804 519 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 67 437 9.0E-81 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain LH59_05975 01e4ca52a88f4833cb604715cace8804 519 PIRSF PIRSF002741 11 511 2.1E-96 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 LH59_05975 01e4ca52a88f4833cb604715cace8804 519 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 73 95 - T 14-10-2018 IPR023765 Solute-binding protein family 5, conserved site LH59_00100 aa3235a57f689589002042c8f25f83ee 387 SUPERFAMILY SSF51395 8 373 1.04E-105 T 14-10-2018 LH59_00100 aa3235a57f689589002042c8f25f83ee 387 Pfam PF01070 FMN-dependent dehydrogenase 18 378 4.8E-134 T 14-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 LH59_00100 aa3235a57f689589002042c8f25f83ee 387 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 278 284 - T 14-10-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 Reactome: R-HSA-9033241 LH59_00100 aa3235a57f689589002042c8f25f83ee 387 Gene3D G3DSA:3.20.20.70 7 382 7.8E-133 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_00100 aa3235a57f689589002042c8f25f83ee 387 PIRSF PIRSF000138 1 382 5.7E-125 T 14-10-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 Reactome: R-HSA-9033241 LH59_14465 f23fccf50d2cc3276488d536cc71f303 431 Gene3D G3DSA:3.40.640.10 10 293 3.7E-102 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_14465 f23fccf50d2cc3276488d536cc71f303 431 SUPERFAMILY SSF53383 9 429 4.26E-130 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_14465 f23fccf50d2cc3276488d536cc71f303 431 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 12 428 2.8E-141 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 LH59_14465 f23fccf50d2cc3276488d536cc71f303 431 Gene3D G3DSA:3.90.1150.10 297 431 5.7E-50 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_14465 f23fccf50d2cc3276488d536cc71f303 431 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 11 429 1.6E-196 T 14-10-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 LH59_14465 f23fccf50d2cc3276488d536cc71f303 431 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 204 218 - T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 LH59_14465 f23fccf50d2cc3276488d536cc71f303 431 PIRSF PIRSF001434 1 431 3.8E-130 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 LH59_24310 32cbe7d010735f12288593686d9b3ed9 164 SMART SM00347 46 146 8.9E-16 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_24310 32cbe7d010735f12288593686d9b3ed9 164 SUPERFAMILY SSF46785 22 158 1.42E-27 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_24310 32cbe7d010735f12288593686d9b3ed9 164 Gene3D G3DSA:1.10.10.10 6 159 1.1E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_24310 32cbe7d010735f12288593686d9b3ed9 164 Pfam PF12802 MarR family 52 110 7.4E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_24310 32cbe7d010735f12288593686d9b3ed9 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 102 5.5E-6 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_24310 32cbe7d010735f12288593686d9b3ed9 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 106 122 5.5E-6 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_24310 32cbe7d010735f12288593686d9b3ed9 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 86 5.5E-6 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_14440 bf917c68e98fb5a133be664ee3be4518 270 SUPERFAMILY SSF52540 9 236 7.53E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_14440 bf917c68e98fb5a133be664ee3be4518 270 SMART SM00382 35 218 2.4E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_14440 bf917c68e98fb5a133be664ee3be4518 270 Gene3D G3DSA:3.40.50.300 7 228 9.9E-58 T 14-10-2018 LH59_14440 bf917c68e98fb5a133be664ee3be4518 270 Pfam PF00005 ABC transporter 27 168 3.7E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_09935 f76ebdfe20a721fbd05ddb62aad88b97 409 SMART SM00267 209 380 8.3E-51 T 14-10-2018 IPR000160 GGDEF domain LH59_09935 f76ebdfe20a721fbd05ddb62aad88b97 409 Gene3D G3DSA:3.30.70.270 213 385 1.7E-53 T 14-10-2018 LH59_09935 f76ebdfe20a721fbd05ddb62aad88b97 409 Pfam PF00990 Diguanylate cyclase, GGDEF domain 222 376 4.6E-39 T 14-10-2018 IPR000160 GGDEF domain LH59_09935 f76ebdfe20a721fbd05ddb62aad88b97 409 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 221 379 1.8E-44 T 14-10-2018 IPR000160 GGDEF domain LH59_09935 f76ebdfe20a721fbd05ddb62aad88b97 409 SUPERFAMILY SSF55073 225 379 6.75E-47 T 14-10-2018 IPR029787 Nucleotide cyclase LH59_07250 77feb5efe1727d2d28541d28a6e8dff2 242 Pfam PF13489 Methyltransferase domain 59 212 1.3E-27 T 14-10-2018 LH59_07250 77feb5efe1727d2d28541d28a6e8dff2 242 Gene3D G3DSA:3.40.50.150 19 242 1.4E-77 T 14-10-2018 LH59_07250 77feb5efe1727d2d28541d28a6e8dff2 242 SUPERFAMILY SSF53335 21 223 9.53E-50 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_07250 77feb5efe1727d2d28541d28a6e8dff2 242 Hamap MF_00472 Ubiquinone biosynthesis O-methyltransferase [ubiG]. 19 242 36.362 T 14-10-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 LH59_07250 77feb5efe1727d2d28541d28a6e8dff2 242 TIGRFAM TIGR01983 UbiG: 3-demethylubiquinone-9 3-O-methyltransferase 19 237 8.2E-86 T 14-10-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 LH59_18625 fd153d2b49b22d5bc9f844e045186d43 148 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 14 143 1.2E-28 T 14-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like LH59_18625 fd153d2b49b22d5bc9f844e045186d43 148 SUPERFAMILY SSF55961 2 145 3.06E-44 T 14-10-2018 LH59_18625 fd153d2b49b22d5bc9f844e045186d43 148 Gene3D G3DSA:3.30.530.20 3 147 1.9E-38 T 14-10-2018 IPR023393 START-like domain superfamily LH59_25060 83065ba805ac80c86d3177f686becc2e 308 Gene3D G3DSA:1.10.10.10 1 90 5.3E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_25060 83065ba805ac80c86d3177f686becc2e 308 Gene3D G3DSA:3.40.190.290 91 294 3.0E-37 T 14-10-2018 LH59_25060 83065ba805ac80c86d3177f686becc2e 308 SUPERFAMILY SSF53850 87 297 4.21E-34 T 14-10-2018 LH59_25060 83065ba805ac80c86d3177f686becc2e 308 Pfam PF03466 LysR substrate binding domain 85 284 5.0E-33 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_25060 83065ba805ac80c86d3177f686becc2e 308 SUPERFAMILY SSF46785 1 106 4.19E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_25060 83065ba805ac80c86d3177f686becc2e 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.8E-19 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_13025 15ee846727df2b8d57bdc6e87f6f6407 312 PRINTS PR00116 Arginase signature 100 115 2.5E-43 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 LH59_13025 15ee846727df2b8d57bdc6e87f6f6407 312 PRINTS PR00116 Arginase signature 264 278 2.5E-43 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 LH59_13025 15ee846727df2b8d57bdc6e87f6f6407 312 PRINTS PR00116 Arginase signature 229 258 2.5E-43 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 LH59_13025 15ee846727df2b8d57bdc6e87f6f6407 312 PRINTS PR00116 Arginase signature 181 199 2.5E-43 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 LH59_13025 15ee846727df2b8d57bdc6e87f6f6407 312 PRINTS PR00116 Arginase signature 127 154 2.5E-43 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 LH59_13025 15ee846727df2b8d57bdc6e87f6f6407 312 Pfam PF00491 Arginase family 10 302 1.6E-74 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 LH59_13025 15ee846727df2b8d57bdc6e87f6f6407 312 SUPERFAMILY SSF52768 11 306 3.06E-87 T 14-10-2018 IPR023696 Ureohydrolase domain superfamily LH59_13025 15ee846727df2b8d57bdc6e87f6f6407 312 TIGRFAM TIGR01229 rocF_arginase: arginase 13 306 2.6E-84 T 14-10-2018 IPR014033 Arginase GO:0004053|GO:0006525|GO:0046872 KEGG: 00220+3.5.3.1|KEGG: 00330+3.5.3.1|MetaCyc: PWY-31|MetaCyc: PWY-4984|MetaCyc: PWY-6305|MetaCyc: PWY-6922|Reactome: R-HSA-70635 LH59_13025 15ee846727df2b8d57bdc6e87f6f6407 312 ProSitePatterns PS01053 Arginase family signature. 232 253 - T 14-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 LH59_13025 15ee846727df2b8d57bdc6e87f6f6407 312 PIRSF PIRSF036979 2 306 5.9E-30 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 LH59_13025 15ee846727df2b8d57bdc6e87f6f6407 312 Gene3D G3DSA:3.40.800.10 9 307 1.3E-90 T 14-10-2018 LH59_26305 a5929c2dfcf3f5f00a72287b85dae3de 86 Gene3D G3DSA:2.40.50.1030 6 85 1.1E-27 T 14-10-2018 LH59_26305 a5929c2dfcf3f5f00a72287b85dae3de 86 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 14-10-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_26305 a5929c2dfcf3f5f00a72287b85dae3de 86 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 73 8.0E-15 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_26305 a5929c2dfcf3f5f00a72287b85dae3de 86 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 85 28.164 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_26305 a5929c2dfcf3f5f00a72287b85dae3de 86 Pfam PF01016 Ribosomal L27 protein 2 81 3.2E-36 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_26305 a5929c2dfcf3f5f00a72287b85dae3de 86 PRINTS PR00063 Ribosomal protein L27 signature 29 53 1.7E-36 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_26305 a5929c2dfcf3f5f00a72287b85dae3de 86 PRINTS PR00063 Ribosomal protein L27 signature 4 28 1.7E-36 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_26305 a5929c2dfcf3f5f00a72287b85dae3de 86 PRINTS PR00063 Ribosomal protein L27 signature 54 78 1.7E-36 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_26305 a5929c2dfcf3f5f00a72287b85dae3de 86 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 83 7.9E-39 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_26305 a5929c2dfcf3f5f00a72287b85dae3de 86 SUPERFAMILY SSF110324 2 81 1.6E-32 T 14-10-2018 LH59_27670 39683b2dd39479042976d0d0ba700b22 430 Gene3D G3DSA:3.20.20.10 47 291 1.6E-145 T 14-10-2018 IPR029066 PLP-binding barrel LH59_27670 39683b2dd39479042976d0d0ba700b22 430 Gene3D G3DSA:2.40.37.10 29 423 1.6E-145 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 LH59_27670 39683b2dd39479042976d0d0ba700b22 430 SUPERFAMILY SSF51419 39 298 6.98E-80 T 14-10-2018 IPR029066 PLP-binding barrel LH59_27670 39683b2dd39479042976d0d0ba700b22 430 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 70 88 9.3E-24 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 LH59_27670 39683b2dd39479042976d0d0ba700b22 430 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 286 305 9.3E-24 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 LH59_27670 39683b2dd39479042976d0d0ba700b22 430 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 384 397 9.3E-24 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 LH59_27670 39683b2dd39479042976d0d0ba700b22 430 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 90 102 9.3E-24 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 LH59_27670 39683b2dd39479042976d0d0ba700b22 430 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 203 216 9.3E-24 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 LH59_27670 39683b2dd39479042976d0d0ba700b22 430 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 43 384 9.6E-24 T 14-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 LH59_27670 39683b2dd39479042976d0d0ba700b22 430 SUPERFAMILY SSF50621 273 427 2.3E-51 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 LH59_27670 39683b2dd39479042976d0d0ba700b22 430 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 28 427 41.597 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LH59_27670 39683b2dd39479042976d0d0ba700b22 430 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 49 295 2.9E-68 T 14-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 LH59_27670 39683b2dd39479042976d0d0ba700b22 430 PRINTS PR01181 Diaminopimelate decarboxylase signature 177 186 1.6E-31 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LH59_27670 39683b2dd39479042976d0d0ba700b22 430 PRINTS PR01181 Diaminopimelate decarboxylase signature 394 416 1.6E-31 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LH59_27670 39683b2dd39479042976d0d0ba700b22 430 PRINTS PR01181 Diaminopimelate decarboxylase signature 88 105 1.6E-31 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LH59_27670 39683b2dd39479042976d0d0ba700b22 430 PRINTS PR01181 Diaminopimelate decarboxylase signature 314 332 1.6E-31 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LH59_27670 39683b2dd39479042976d0d0ba700b22 430 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 20 426 3.0E-152 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LH59_06905 7bf1feaa2f2f9d7e43bff23d080c68ac 238 SUPERFAMILY SSF46548 108 236 3.49E-39 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 LH59_06905 7bf1feaa2f2f9d7e43bff23d080c68ac 238 Pfam PF13534 4Fe-4S dicluster domain 148 221 4.2E-10 T 14-10-2018 LH59_06905 7bf1feaa2f2f9d7e43bff23d080c68ac 238 Gene3D G3DSA:3.10.20.30 1 107 8.1E-39 T 14-10-2018 IPR012675 Beta-grasp domain superfamily LH59_06905 7bf1feaa2f2f9d7e43bff23d080c68ac 238 SUPERFAMILY SSF54292 5 107 4.01E-30 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 LH59_06905 7bf1feaa2f2f9d7e43bff23d080c68ac 238 Gene3D G3DSA:1.10.1060.10 108 238 8.1E-58 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 LH59_06905 7bf1feaa2f2f9d7e43bff23d080c68ac 238 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 8 113 1.0E-33 T 14-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 LH59_06905 7bf1feaa2f2f9d7e43bff23d080c68ac 238 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 11 230 2.2E-85 T 14-10-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 LH59_06905 7bf1feaa2f2f9d7e43bff23d080c68ac 238 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 149 160 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site LH59_24055 0aae3b124dc6fc70f09e583d4669ac10 571 Pfam PF00005 ABC transporter 339 488 2.0E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_24055 0aae3b124dc6fc70f09e583d4669ac10 571 SUPERFAMILY SSF90123 1 310 6.41E-44 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 LH59_24055 0aae3b124dc6fc70f09e583d4669ac10 571 Gene3D G3DSA:1.20.1560.10 1 309 3.4E-35 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 LH59_24055 0aae3b124dc6fc70f09e583d4669ac10 571 SMART SM00382 348 534 1.4E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_24055 0aae3b124dc6fc70f09e583d4669ac10 571 Pfam PF00664 ABC transporter transmembrane region 47 272 8.3E-19 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 LH59_24055 0aae3b124dc6fc70f09e583d4669ac10 571 ProSitePatterns PS00211 ABC transporters family signature. 460 474 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_24055 0aae3b124dc6fc70f09e583d4669ac10 571 Gene3D G3DSA:3.40.50.300 317 565 4.3E-86 T 14-10-2018 LH59_24055 0aae3b124dc6fc70f09e583d4669ac10 571 SUPERFAMILY SSF52540 317 557 4.91E-85 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_17460 88725a9ffb0905160dfd2bcdcec9060a 991 Pfam PF09718 Lambda phage tail tape-measure protein (Tape_meas_lam_C) 743 817 9.0E-25 T 14-10-2018 IPR006431 Bacteriophage lambda, GpH, tail tape measure, C-terminal LH59_17460 88725a9ffb0905160dfd2bcdcec9060a 991 TIGRFAM TIGR01541 tape_meas_lam_C: phage tail tape measure protein, lambda family 613 940 7.0E-48 T 14-10-2018 IPR006431 Bacteriophage lambda, GpH, tail tape measure, C-terminal LH59_17460 88725a9ffb0905160dfd2bcdcec9060a 991 Pfam PF06791 Prophage tail length tape measure protein 129 332 3.4E-68 T 14-10-2018 IPR009628 Bacteriophage lambda, GpH, tail tape measure, N-terminal LH59_22360 fd5113cd6bbe84ef49212651e3309d10 436 PRINTS PR00173 Glutamate-aspartate symporter signature 358 378 6.2E-42 T 14-10-2018 LH59_22360 fd5113cd6bbe84ef49212651e3309d10 436 PRINTS PR00173 Glutamate-aspartate symporter signature 81 106 6.2E-42 T 14-10-2018 LH59_22360 fd5113cd6bbe84ef49212651e3309d10 436 PRINTS PR00173 Glutamate-aspartate symporter signature 148 170 6.2E-42 T 14-10-2018 LH59_22360 fd5113cd6bbe84ef49212651e3309d10 436 PRINTS PR00173 Glutamate-aspartate symporter signature 331 350 6.2E-42 T 14-10-2018 LH59_22360 fd5113cd6bbe84ef49212651e3309d10 436 PRINTS PR00173 Glutamate-aspartate symporter signature 51 71 6.2E-42 T 14-10-2018 LH59_22360 fd5113cd6bbe84ef49212651e3309d10 436 PRINTS PR00173 Glutamate-aspartate symporter signature 296 322 6.2E-42 T 14-10-2018 LH59_22360 fd5113cd6bbe84ef49212651e3309d10 436 PRINTS PR00173 Glutamate-aspartate symporter signature 4 24 6.2E-42 T 14-10-2018 LH59_22360 fd5113cd6bbe84ef49212651e3309d10 436 PRINTS PR00173 Glutamate-aspartate symporter signature 196 215 6.2E-42 T 14-10-2018 LH59_22360 fd5113cd6bbe84ef49212651e3309d10 436 Gene3D G3DSA:1.10.3860.10 1 419 7.5E-122 T 14-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 LH59_22360 fd5113cd6bbe84ef49212651e3309d10 436 SUPERFAMILY SSF118215 6 405 5.23E-115 T 14-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 LH59_22360 fd5113cd6bbe84ef49212651e3309d10 436 Pfam PF00375 Sodium:dicarboxylate symporter family 9 404 6.5E-112 T 14-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 LH59_13955 76fb77028c5b1f6b845bd1434b194d84 458 PIRSF PIRSF000337 3 447 1.5E-168 T 14-10-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 LH59_13955 76fb77028c5b1f6b845bd1434b194d84 458 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 10 432 2.4E-187 T 14-10-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 LH59_13955 76fb77028c5b1f6b845bd1434b194d84 458 SUPERFAMILY SSF51679 5 438 3.27E-143 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 LH59_13955 76fb77028c5b1f6b845bd1434b194d84 458 Pfam PF00296 Luciferase-like monooxygenase 19 390 6.7E-71 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LH59_13955 76fb77028c5b1f6b845bd1434b194d84 458 Gene3D G3DSA:3.20.20.30 2 451 2.1E-169 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 LH59_00605 89e3e36faf1a31dd5568fe085a0a392d 208 Pfam PF01810 LysE type translocator 16 205 5.9E-38 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 LH59_00605 89e3e36faf1a31dd5568fe085a0a392d 208 PIRSF PIRSF006324 1 208 7.9E-53 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 LH59_00110 ae5b25c259486fb47f7a90ccec2829ef 356 Gene3D G3DSA:2.40.50.940 222 281 3.1E-8 T 14-10-2018 LH59_00110 ae5b25c259486fb47f7a90ccec2829ef 356 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_00110 ae5b25c259486fb47f7a90ccec2829ef 356 Pfam PF08402 TOBE domain 275 347 1.8E-8 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 LH59_00110 ae5b25c259486fb47f7a90ccec2829ef 356 SMART SM00382 28 211 2.7E-20 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_00110 ae5b25c259486fb47f7a90ccec2829ef 356 Gene3D G3DSA:2.40.50.140 282 339 3.1E-8 T 14-10-2018 LH59_00110 ae5b25c259486fb47f7a90ccec2829ef 356 SUPERFAMILY SSF50331 238 342 7.23E-11 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal LH59_00110 ae5b25c259486fb47f7a90ccec2829ef 356 Pfam PF00005 ABC transporter 20 161 8.6E-35 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_00110 ae5b25c259486fb47f7a90ccec2829ef 356 SUPERFAMILY SSF52540 4 242 3.51E-87 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_00110 ae5b25c259486fb47f7a90ccec2829ef 356 Gene3D G3DSA:3.40.50.300 3 221 2.3E-70 T 14-10-2018 LH59_16415 fc9b220abaf2beffe733442e24b16f1e 249 Pfam PF01223 DNA/RNA non-specific endonuclease 61 216 3.7E-40 T 14-10-2018 IPR001604 DNA/RNA non-specific endonuclease GO:0003676|GO:0016787|GO:0046872 LH59_16415 fc9b220abaf2beffe733442e24b16f1e 249 SMART SM00892 62 242 9.5E-33 T 14-10-2018 IPR001604 DNA/RNA non-specific endonuclease GO:0003676|GO:0016787|GO:0046872 LH59_16415 fc9b220abaf2beffe733442e24b16f1e 249 SMART SM00477 63 249 1.4E-17 T 14-10-2018 IPR020821 Extracellular Endonuclease, subunit A GO:0003676|GO:0016787|GO:0046872 LH59_16415 fc9b220abaf2beffe733442e24b16f1e 249 SUPERFAMILY SSF54060 39 248 4.88E-55 T 14-10-2018 LH59_16415 fc9b220abaf2beffe733442e24b16f1e 249 Gene3D G3DSA:3.40.570.10 47 249 4.7E-47 T 14-10-2018 LH59_16995 aba1d6e6bff12f07e8f82aad17cf7396 263 Pfam PF02110 Hydroxyethylthiazole kinase family 11 252 5.5E-77 T 14-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 LH59_16995 aba1d6e6bff12f07e8f82aad17cf7396 263 SUPERFAMILY SSF53613 8 252 1.12E-58 T 14-10-2018 IPR029056 Ribokinase-like LH59_16995 aba1d6e6bff12f07e8f82aad17cf7396 263 Hamap MF_00228 Hydroxyethylthiazole kinase [thiM]. 11 257 31.599 T 14-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 LH59_16995 aba1d6e6bff12f07e8f82aad17cf7396 263 TIGRFAM TIGR00694 thiM: hydroxyethylthiazole kinase 11 254 2.9E-78 T 14-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 LH59_16995 aba1d6e6bff12f07e8f82aad17cf7396 263 Gene3D G3DSA:3.40.1190.20 4 260 4.3E-89 T 14-10-2018 IPR029056 Ribokinase-like LH59_16995 aba1d6e6bff12f07e8f82aad17cf7396 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 17 24 3.2E-37 T 14-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 LH59_16995 aba1d6e6bff12f07e8f82aad17cf7396 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 161 178 3.2E-37 T 14-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 LH59_16995 aba1d6e6bff12f07e8f82aad17cf7396 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 30 51 3.2E-37 T 14-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 LH59_16995 aba1d6e6bff12f07e8f82aad17cf7396 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 61 69 3.2E-37 T 14-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 LH59_16995 aba1d6e6bff12f07e8f82aad17cf7396 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 87 104 3.2E-37 T 14-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 LH59_16995 aba1d6e6bff12f07e8f82aad17cf7396 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 117 131 3.2E-37 T 14-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 LH59_16995 aba1d6e6bff12f07e8f82aad17cf7396 263 PIRSF PIRSF000513 5 261 9.0E-90 T 14-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 LH59_17165 39076588fd07da9025157253805f33ba 113 SUPERFAMILY SSF54292 8 109 7.64E-28 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 LH59_17165 39076588fd07da9025157253805f33ba 113 Gene3D G3DSA:3.10.20.30 1 113 4.7E-31 T 14-10-2018 IPR012675 Beta-grasp domain superfamily LH59_17165 39076588fd07da9025157253805f33ba 113 PRINTS PR00355 Adrenodoxin signature 84 92 6.0E-9 T 14-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 LH59_17165 39076588fd07da9025157253805f33ba 113 PRINTS PR00355 Adrenodoxin signature 61 75 6.0E-9 T 14-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 LH59_17165 39076588fd07da9025157253805f33ba 113 PRINTS PR00355 Adrenodoxin signature 43 53 6.0E-9 T 14-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 LH59_17165 39076588fd07da9025157253805f33ba 113 TIGRFAM TIGR02007 fdx_isc: ferredoxin, 2Fe-2S type, ISC system 2 111 4.9E-52 T 14-10-2018 IPR011536 Ferredoxin 2Fe-2S type, proteobacteria GO:0009055|GO:0051537 LH59_17165 39076588fd07da9025157253805f33ba 113 ProSitePatterns PS00814 Adrenodoxin family, iron-sulfur binding region signature. 43 53 - T 14-10-2018 IPR018298 Adrenodoxin, iron-sulphur binding site GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 LH59_17165 39076588fd07da9025157253805f33ba 113 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 19 93 4.0E-12 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 LH59_13580 1c06b14798e1750c27d6e68252939ca9 241 SUPERFAMILY SSF55120 66 239 3.5E-18 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 LH59_13580 1c06b14798e1750c27d6e68252939ca9 241 Pfam PF01479 S4 domain 5 51 3.5E-9 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_13580 1c06b14798e1750c27d6e68252939ca9 241 SUPERFAMILY SSF55174 6 85 1.7E-13 T 14-10-2018 LH59_13580 1c06b14798e1750c27d6e68252939ca9 241 Gene3D G3DSA:3.30.2350.10 64 240 1.6E-23 T 14-10-2018 LH59_13580 1c06b14798e1750c27d6e68252939ca9 241 Gene3D G3DSA:3.10.290.10 2 63 1.9E-14 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 LH59_13580 1c06b14798e1750c27d6e68252939ca9 241 Pfam PF00849 RNA pseudouridylate synthase 67 154 1.2E-6 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 LH59_13580 1c06b14798e1750c27d6e68252939ca9 241 SMART SM00363 5 70 7.6E-5 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_18175 b3f66e0a44033d9d5293bb7734a452c8 548 SUPERFAMILY SSF89550 56 365 1.16E-15 T 14-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 LH59_03025 d3a3a2ac8e774ea7bca8f77e8585abc2 260 Gene3D G3DSA:3.40.1190.20 1 258 9.5E-37 T 14-10-2018 IPR029056 Ribokinase-like LH59_03025 d3a3a2ac8e774ea7bca8f77e8585abc2 260 SUPERFAMILY SSF53613 1 256 1.78E-33 T 14-10-2018 IPR029056 Ribokinase-like LH59_03025 d3a3a2ac8e774ea7bca8f77e8585abc2 260 Pfam PF08543 Phosphomethylpyrimidine kinase 7 250 1.6E-34 T 14-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 LH59_24655 fb794d7d09f39ec85111798657232e2b 237 Pfam PF00486 Transcriptional regulatory protein, C terminal 157 230 2.0E-17 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_24655 fb794d7d09f39ec85111798657232e2b 237 Gene3D G3DSA:1.10.10.10 134 236 2.5E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_24655 fb794d7d09f39ec85111798657232e2b 237 Gene3D G3DSA:3.40.50.2300 2 133 3.9E-32 T 14-10-2018 LH59_24655 fb794d7d09f39ec85111798657232e2b 237 Pfam PF00072 Response regulator receiver domain 13 121 2.7E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_24655 fb794d7d09f39ec85111798657232e2b 237 SMART SM00448 11 123 3.0E-36 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_24655 fb794d7d09f39ec85111798657232e2b 237 SMART SM00862 157 230 1.0E-19 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_24655 fb794d7d09f39ec85111798657232e2b 237 SUPERFAMILY SSF52172 10 177 2.28E-35 T 14-10-2018 IPR011006 CheY-like superfamily LH59_01440 fef389fb807c813e7db9d95a94236f85 240 Pfam PF07702 UTRA domain 96 233 6.6E-38 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LH59_01440 fef389fb807c813e7db9d95a94236f85 240 Gene3D G3DSA:1.10.10.10 10 80 2.7E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_01440 fef389fb807c813e7db9d95a94236f85 240 Gene3D G3DSA:3.40.1410.10 94 229 1.1E-38 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily LH59_01440 fef389fb807c813e7db9d95a94236f85 240 TIGRFAM TIGR02018 his_ut_repres: histidine utilization repressor 11 239 1.6E-105 T 14-10-2018 IPR010248 Histidine utilization repressor GO:0003677|GO:0006547|GO:0045892 LH59_01440 fef389fb807c813e7db9d95a94236f85 240 SMART SM00866 96 233 3.5E-37 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LH59_01440 fef389fb807c813e7db9d95a94236f85 240 SUPERFAMILY SSF46785 10 79 1.52E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_01440 fef389fb807c813e7db9d95a94236f85 240 SUPERFAMILY SSF64288 63 236 4.4E-46 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily LH59_01440 fef389fb807c813e7db9d95a94236f85 240 SMART SM00345 16 75 3.8E-19 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_01440 fef389fb807c813e7db9d95a94236f85 240 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 65 2.9E-9 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_01440 fef389fb807c813e7db9d95a94236f85 240 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 49 2.9E-9 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_01440 fef389fb807c813e7db9d95a94236f85 240 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 75 2.2E-19 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_10655 7332bbdd83b415b591275144530847de 148 SUPERFAMILY SSF55811 6 125 9.21E-35 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 LH59_10655 7332bbdd83b415b591275144530847de 148 Gene3D G3DSA:3.90.79.10 2 137 5.6E-34 T 14-10-2018 LH59_10655 7332bbdd83b415b591275144530847de 148 Pfam PF00293 NUDIX domain 12 122 5.5E-22 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 LH59_10655 7332bbdd83b415b591275144530847de 148 PRINTS PR00502 NUDIX hydrolase family signature 50 65 5.7E-8 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 LH59_10655 7332bbdd83b415b591275144530847de 148 PRINTS PR00502 NUDIX hydrolase family signature 36 50 5.7E-8 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 LH59_08535 75d1e668b78b130468b28153ddf7f667 341 PRINTS PR00344 Bacterial sensor protein C-terminal signature 288 306 1.2E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_08535 75d1e668b78b130468b28153ddf7f667 341 PRINTS PR00344 Bacterial sensor protein C-terminal signature 274 284 1.2E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_08535 75d1e668b78b130468b28153ddf7f667 341 PRINTS PR00344 Bacterial sensor protein C-terminal signature 256 270 1.2E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_08535 75d1e668b78b130468b28153ddf7f667 341 SMART SM00388 109 174 5.0E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_08535 75d1e668b78b130468b28153ddf7f667 341 SMART SM00387 221 329 3.2E-32 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_08535 75d1e668b78b130468b28153ddf7f667 341 Gene3D G3DSA:1.10.287.130 58 175 7.0E-17 T 14-10-2018 LH59_08535 75d1e668b78b130468b28153ddf7f667 341 SUPERFAMILY SSF55874 164 326 9.95E-33 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_08535 75d1e668b78b130468b28153ddf7f667 341 Gene3D G3DSA:3.30.565.10 182 327 1.7E-30 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_08535 75d1e668b78b130468b28153ddf7f667 341 SUPERFAMILY SSF47384 92 173 4.32E-14 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 LH59_08535 75d1e668b78b130468b28153ddf7f667 341 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 222 326 2.2E-18 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_08535 75d1e668b78b130468b28153ddf7f667 341 Pfam PF00512 His Kinase A (phospho-acceptor) domain 109 172 3.2E-10 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_20240 f19477723a9c7b4f3cefa1ce21ce5d55 424 SMART SM00052 150 391 3.3E-52 T 14-10-2018 IPR001633 EAL domain LH59_20240 f19477723a9c7b4f3cefa1ce21ce5d55 424 Gene3D G3DSA:3.40.50.2300 1 143 1.1E-22 T 14-10-2018 LH59_20240 f19477723a9c7b4f3cefa1ce21ce5d55 424 Gene3D G3DSA:3.20.20.450 151 407 1.2E-65 T 14-10-2018 IPR035919 EAL domain superfamily LH59_20240 f19477723a9c7b4f3cefa1ce21ce5d55 424 SUPERFAMILY SSF52172 5 132 1.71E-21 T 14-10-2018 IPR011006 CheY-like superfamily LH59_20240 f19477723a9c7b4f3cefa1ce21ce5d55 424 SMART SM00448 7 124 5.1E-15 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_20240 f19477723a9c7b4f3cefa1ce21ce5d55 424 SUPERFAMILY SSF141868 154 398 9.55E-61 T 14-10-2018 IPR035919 EAL domain superfamily LH59_20240 f19477723a9c7b4f3cefa1ce21ce5d55 424 Pfam PF00072 Response regulator receiver domain 9 92 5.1E-16 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_20240 f19477723a9c7b4f3cefa1ce21ce5d55 424 Pfam PF00563 EAL domain 153 385 1.5E-53 T 14-10-2018 IPR001633 EAL domain LH59_22250 abb4cf985b28341ecee48dfaf967fdd2 519 Pfam PF13193 AMP-binding enzyme C-terminal domain 427 505 1.5E-20 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain LH59_22250 abb4cf985b28341ecee48dfaf967fdd2 519 TIGRFAM TIGR02262 benz_CoA_lig: benzoate-CoA ligase family 8 513 2.1E-237 T 14-10-2018 IPR011957 Benzoate-CoA ligase family GO:0005524|GO:0016405 LH59_22250 abb4cf985b28341ecee48dfaf967fdd2 519 Gene3D G3DSA:3.40.50.980 2 240 3.5E-75 T 14-10-2018 LH59_22250 abb4cf985b28341ecee48dfaf967fdd2 519 Gene3D G3DSA:2.30.38.10 312 418 7.7E-38 T 14-10-2018 LH59_22250 abb4cf985b28341ecee48dfaf967fdd2 519 Pfam PF00501 AMP-binding enzyme 23 419 6.8E-96 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 LH59_22250 abb4cf985b28341ecee48dfaf967fdd2 519 Gene3D G3DSA:1.10.10.2900 241 311 3.6E-31 T 14-10-2018 LH59_22250 abb4cf985b28341ecee48dfaf967fdd2 519 SUPERFAMILY SSF56801 16 515 8.77E-150 T 14-10-2018 LH59_22250 abb4cf985b28341ecee48dfaf967fdd2 519 Gene3D G3DSA:3.30.300.310 419 518 2.4E-30 T 14-10-2018 LH59_08485 841543a26cdd360a3d9aeb2fec12ee96 821 TIGRFAM TIGR02063 RNase_R: ribonuclease R 28 750 8.6E-246 T 14-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 LH59_08485 841543a26cdd360a3d9aeb2fec12ee96 821 SUPERFAMILY SSF50249 76 155 6.49E-17 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_08485 841543a26cdd360a3d9aeb2fec12ee96 821 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 89 750 5.7E-206 T 14-10-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 LH59_08485 841543a26cdd360a3d9aeb2fec12ee96 821 SMART SM00357 95 153 6.5E-12 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 LH59_08485 841543a26cdd360a3d9aeb2fec12ee96 821 Pfam PF08206 Ribonuclease B OB domain 96 152 4.5E-19 T 14-10-2018 IPR013223 Ribonuclease B, N-terminal OB domain LH59_08485 841543a26cdd360a3d9aeb2fec12ee96 821 SMART SM00316 667 750 9.2E-13 T 14-10-2018 IPR022967 RNA-binding domain, S1 LH59_08485 841543a26cdd360a3d9aeb2fec12ee96 821 Gene3D G3DSA:2.40.50.140 670 781 1.5E-20 T 14-10-2018 LH59_08485 841543a26cdd360a3d9aeb2fec12ee96 821 SUPERFAMILY SSF50249 146 245 5.83E-22 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_08485 841543a26cdd360a3d9aeb2fec12ee96 821 SUPERFAMILY SSF50249 228 666 3.2E-133 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_08485 841543a26cdd360a3d9aeb2fec12ee96 821 Pfam PF00773 RNB domain 268 607 1.8E-100 T 14-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 LH59_08485 841543a26cdd360a3d9aeb2fec12ee96 821 Gene3D G3DSA:2.40.50.140 86 156 5.3E-17 T 14-10-2018 LH59_08485 841543a26cdd360a3d9aeb2fec12ee96 821 Pfam PF00575 S1 RNA binding domain 667 747 2.3E-10 T 14-10-2018 IPR003029 S1 domain GO:0003676 LH59_08485 841543a26cdd360a3d9aeb2fec12ee96 821 SMART SM00955 268 608 4.4E-178 T 14-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 LH59_08485 841543a26cdd360a3d9aeb2fec12ee96 821 SUPERFAMILY SSF50249 669 749 1.14E-19 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_08485 841543a26cdd360a3d9aeb2fec12ee96 821 ProSitePatterns PS01175 Ribonuclease II family signature. 575 599 - T 14-10-2018 IPR022966 Ribonuclease II/R, conserved site LH59_08485 841543a26cdd360a3d9aeb2fec12ee96 821 Hamap MF_01895 Ribonuclease R [rnr]. 47 750 54.494 T 14-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 LH59_21310 48f832bae75c42f271d3ca042fca3b3d 323 Gene3D G3DSA:3.40.50.2300 144 315 3.6E-92 T 14-10-2018 LH59_21310 48f832bae75c42f271d3ca042fca3b3d 323 Pfam PF04392 ABC transporter substrate binding protein 30 321 2.6E-112 T 14-10-2018 IPR007487 ABC transporter, substrate-binding protein LH59_21310 48f832bae75c42f271d3ca042fca3b3d 323 Gene3D G3DSA:3.40.50.2300 48 293 3.6E-92 T 14-10-2018 LH59_21310 48f832bae75c42f271d3ca042fca3b3d 323 SUPERFAMILY SSF53822 37 284 1.29E-20 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_24675 16723054e8f94b9a6af9483a549e3422 519 Gene3D G3DSA:3.40.50.10490 86 264 5.2E-157 T 14-10-2018 LH59_24675 16723054e8f94b9a6af9483a549e3422 519 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 467 484 - T 14-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_24675 16723054e8f94b9a6af9483a549e3422 519 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 235 248 - T 14-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_24675 16723054e8f94b9a6af9483a549e3422 519 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 31 494 34.302 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_24675 16723054e8f94b9a6af9483a549e3422 519 Gene3D G3DSA:3.40.50.10490 22 476 5.2E-157 T 14-10-2018 LH59_24675 16723054e8f94b9a6af9483a549e3422 519 Gene3D G3DSA:1.10.1390.10 477 519 3.0E-14 T 14-10-2018 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_24675 16723054e8f94b9a6af9483a549e3422 519 Pfam PF00342 Phosphoglucose isomerase 45 509 2.9E-140 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_24675 16723054e8f94b9a6af9483a549e3422 519 SUPERFAMILY SSF53697 28 516 1.46E-156 T 14-10-2018 LH59_24675 16723054e8f94b9a6af9483a549e3422 519 PRINTS PR00662 Glucose-6-phosphate isomerase signature 308 329 1.3E-47 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_24675 16723054e8f94b9a6af9483a549e3422 519 PRINTS PR00662 Glucose-6-phosphate isomerase signature 467 480 1.3E-47 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_24675 16723054e8f94b9a6af9483a549e3422 519 PRINTS PR00662 Glucose-6-phosphate isomerase signature 122 141 1.3E-47 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_24675 16723054e8f94b9a6af9483a549e3422 519 PRINTS PR00662 Glucose-6-phosphate isomerase signature 453 467 1.3E-47 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_24675 16723054e8f94b9a6af9483a549e3422 519 PRINTS PR00662 Glucose-6-phosphate isomerase signature 231 249 1.3E-47 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_24675 16723054e8f94b9a6af9483a549e3422 519 PRINTS PR00662 Glucose-6-phosphate isomerase signature 435 453 1.3E-47 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_09640 279264bfa5627e135854dcef518b599d 412 SUPERFAMILY SSF111352 2 391 3.27E-126 T 14-10-2018 LH59_09640 279264bfa5627e135854dcef518b599d 412 Gene3D G3DSA:1.10.3430.10 1 412 1.4E-136 T 14-10-2018 IPR029020 Ammonium/urea transporter LH59_09640 279264bfa5627e135854dcef518b599d 412 PRINTS PR00342 Rhesus blood group protein signature 205 223 4.8E-7 T 14-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 LH59_09640 279264bfa5627e135854dcef518b599d 412 PRINTS PR00342 Rhesus blood group protein signature 291 309 4.8E-7 T 14-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 LH59_09640 279264bfa5627e135854dcef518b599d 412 PRINTS PR00342 Rhesus blood group protein signature 105 121 4.8E-7 T 14-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 LH59_09640 279264bfa5627e135854dcef518b599d 412 PRINTS PR00342 Rhesus blood group protein signature 236 258 4.8E-7 T 14-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 LH59_09640 279264bfa5627e135854dcef518b599d 412 Pfam PF00909 Ammonium Transporter Family 8 410 5.0E-122 T 14-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 LH59_09640 279264bfa5627e135854dcef518b599d 412 ProSitePatterns PS01219 Ammonium transporters signature. 166 191 - T 14-10-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 LH59_09640 279264bfa5627e135854dcef518b599d 412 TIGRFAM TIGR00836 amt: ammonium transporter 5 410 3.3E-135 T 14-10-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 LH59_21930 7f4539ef4e6d2e94435fbd4ef55caf09 210 Gene3D G3DSA:3.40.50.150 24 210 6.1E-54 T 14-10-2018 LH59_21930 7f4539ef4e6d2e94435fbd4ef55caf09 210 SUPERFAMILY SSF53335 27 209 1.42E-36 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_21930 7f4539ef4e6d2e94435fbd4ef55caf09 210 Hamap MF_01547 Ribosomal RNA large subunit methyltransferase E [rlmE]. 12 210 30.171 T 14-10-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 LH59_21930 7f4539ef4e6d2e94435fbd4ef55caf09 210 Pfam PF01728 FtsJ-like methyltransferase 28 208 6.1E-53 T 14-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 LH59_21930 7f4539ef4e6d2e94435fbd4ef55caf09 210 PIRSF PIRSF005461 1 210 1.9E-68 T 14-10-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 LH59_13035 b9bc09559c4c6cda841f642f93e57e78 291 SUPERFAMILY SSF55073 134 288 2.82E-43 T 14-10-2018 IPR029787 Nucleotide cyclase LH59_13035 b9bc09559c4c6cda841f642f93e57e78 291 SUPERFAMILY SSF55785 9 106 4.89E-12 T 14-10-2018 IPR035965 PAS domain superfamily LH59_13035 b9bc09559c4c6cda841f642f93e57e78 291 SMART SM00267 118 289 1.5E-47 T 14-10-2018 IPR000160 GGDEF domain LH59_13035 b9bc09559c4c6cda841f642f93e57e78 291 Gene3D G3DSA:3.30.70.270 123 289 1.8E-50 T 14-10-2018 LH59_13035 b9bc09559c4c6cda841f642f93e57e78 291 Pfam PF00989 PAS fold 10 96 1.8E-8 T 14-10-2018 IPR013767 PAS fold GO:0006355 LH59_13035 b9bc09559c4c6cda841f642f93e57e78 291 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 125 287 1.1E-40 T 14-10-2018 IPR000160 GGDEF domain LH59_13035 b9bc09559c4c6cda841f642f93e57e78 291 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 9 117 2.7E-9 T 14-10-2018 IPR000014 PAS domain LH59_13035 b9bc09559c4c6cda841f642f93e57e78 291 Gene3D G3DSA:3.30.450.20 5 121 2.5E-13 T 14-10-2018 LH59_13035 b9bc09559c4c6cda841f642f93e57e78 291 Pfam PF00990 Diguanylate cyclase, GGDEF domain 129 284 3.5E-37 T 14-10-2018 IPR000160 GGDEF domain LH59_13035 b9bc09559c4c6cda841f642f93e57e78 291 SMART SM00091 9 78 5.5E-4 T 14-10-2018 IPR000014 PAS domain LH59_11640 fe742131938076f4d382ca88ebe2e99d 273 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 4 253 6.2E-89 T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 LH59_11640 fe742131938076f4d382ca88ebe2e99d 273 Hamap MF_01974 Methionine aminopeptidase [map]. 2 254 38.682 T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 LH59_11640 fe742131938076f4d382ca88ebe2e99d 273 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 171 189 - T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 LH59_11640 fe742131938076f4d382ca88ebe2e99d 273 Gene3D G3DSA:3.90.230.10 2 260 3.4E-99 T 14-10-2018 LH59_11640 fe742131938076f4d382ca88ebe2e99d 273 Pfam PF00557 Metallopeptidase family M24 11 245 9.3E-49 T 14-10-2018 IPR000994 Peptidase M24 LH59_11640 fe742131938076f4d382ca88ebe2e99d 273 SUPERFAMILY SSF55920 3 255 2.62E-82 T 14-10-2018 IPR036005 Creatinase/aminopeptidase-like LH59_11640 fe742131938076f4d382ca88ebe2e99d 273 PRINTS PR00599 Methionine aminopeptidase-1 signature 73 86 2.4E-19 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 LH59_11640 fe742131938076f4d382ca88ebe2e99d 273 PRINTS PR00599 Methionine aminopeptidase-1 signature 165 177 2.4E-19 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 LH59_11640 fe742131938076f4d382ca88ebe2e99d 273 PRINTS PR00599 Methionine aminopeptidase-1 signature 196 208 2.4E-19 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 LH59_11640 fe742131938076f4d382ca88ebe2e99d 273 PRINTS PR00599 Methionine aminopeptidase-1 signature 95 111 2.4E-19 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 LH59_06550 7b9c7369b140433702e68e6ee15c7301 294 Pfam PF00717 Peptidase S24-like 96 178 8.5E-22 T 14-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C LH59_06550 7b9c7369b140433702e68e6ee15c7301 294 Gene3D G3DSA:2.10.109.10 88 284 1.5E-74 T 14-10-2018 LH59_06550 7b9c7369b140433702e68e6ee15c7301 294 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 75 284 5.4E-52 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 LH59_06550 7b9c7369b140433702e68e6ee15c7301 294 Pfam PF10502 Signal peptidase, peptidase S26 243 281 8.4E-7 T 14-10-2018 IPR019533 Peptidase S26 LH59_06550 7b9c7369b140433702e68e6ee15c7301 294 ProSitePatterns PS00501 Signal peptidases I serine active site. 99 106 - T 14-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 LH59_06550 7b9c7369b140433702e68e6ee15c7301 294 ProSitePatterns PS00760 Signal peptidases I lysine active site. 156 168 - T 14-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 LH59_06550 7b9c7369b140433702e68e6ee15c7301 294 SUPERFAMILY SSF51306 88 290 1.6E-68 T 14-10-2018 IPR036286 LexA/Signal peptidase-like superfamily LH59_06550 7b9c7369b140433702e68e6ee15c7301 294 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 154 166 3.1E-25 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 LH59_06550 7b9c7369b140433702e68e6ee15c7301 294 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 244 263 3.1E-25 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 LH59_06550 7b9c7369b140433702e68e6ee15c7301 294 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 90 106 3.1E-25 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 LH59_06550 7b9c7369b140433702e68e6ee15c7301 294 Gene3D G3DSA:2.170.230.10 165 243 1.5E-74 T 14-10-2018 LH59_20350 3aaeacdacddec0fde3fbba0b189f77be 527 Pfam PF03741 Integral membrane protein TerC family 14 204 1.6E-48 T 14-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 LH59_20350 3aaeacdacddec0fde3fbba0b189f77be 527 Gene3D G3DSA:3.10.580.10 279 432 1.1E-48 T 14-10-2018 LH59_20350 3aaeacdacddec0fde3fbba0b189f77be 527 Pfam PF03471 Transporter associated domain 432 513 8.7E-23 T 14-10-2018 IPR005170 Transporter-associated domain LH59_20350 3aaeacdacddec0fde3fbba0b189f77be 527 Gene3D G3DSA:3.30.465.10 435 513 6.3E-18 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 LH59_20350 3aaeacdacddec0fde3fbba0b189f77be 527 SUPERFAMILY SSF54631 285 419 4.8E-21 T 14-10-2018 LH59_20350 3aaeacdacddec0fde3fbba0b189f77be 527 SMART SM01091 429 514 1.2E-22 T 14-10-2018 IPR005170 Transporter-associated domain LH59_20350 3aaeacdacddec0fde3fbba0b189f77be 527 SUPERFAMILY SSF56176 426 517 5.18E-21 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 LH59_22235 b5039fbafcdde2b02222dbb91c306a10 303 SUPERFAMILY SSF47413 16 86 1.35E-14 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 LH59_22235 b5039fbafcdde2b02222dbb91c306a10 303 SUPERFAMILY SSF52540 131 289 1.14E-20 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_22235 b5039fbafcdde2b02222dbb91c306a10 303 Hamap MF_00109 Shikimate kinase [aroK]. 129 296 20.299 T 14-10-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 LH59_22235 b5039fbafcdde2b02222dbb91c306a10 303 SMART SM00530 25 80 6.5E-11 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LH59_22235 b5039fbafcdde2b02222dbb91c306a10 303 Pfam PF01381 Helix-turn-helix 27 80 3.7E-10 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LH59_22235 b5039fbafcdde2b02222dbb91c306a10 303 Pfam PF01202 Shikimate kinase 138 287 2.4E-32 T 14-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 LH59_22235 b5039fbafcdde2b02222dbb91c306a10 303 Gene3D G3DSA:3.40.50.300 121 298 2.0E-40 T 14-10-2018 LH59_22235 b5039fbafcdde2b02222dbb91c306a10 303 Gene3D G3DSA:1.10.260.40 20 92 1.6E-13 T 14-10-2018 LH59_22235 b5039fbafcdde2b02222dbb91c306a10 303 PRINTS PR01100 Shikimate kinase family signature 184 192 7.6E-12 T 14-10-2018 LH59_22235 b5039fbafcdde2b02222dbb91c306a10 303 PRINTS PR01100 Shikimate kinase family signature 156 169 7.6E-12 T 14-10-2018 LH59_22235 b5039fbafcdde2b02222dbb91c306a10 303 PRINTS PR01100 Shikimate kinase family signature 132 147 7.6E-12 T 14-10-2018 LH59_22235 b5039fbafcdde2b02222dbb91c306a10 303 PRINTS PR01100 Shikimate kinase family signature 203 212 7.6E-12 T 14-10-2018 LH59_21010 8c666c5d4c0566125548820be3c3d636 194 Pfam PF07883 Cupin domain 128 185 8.7E-13 T 14-10-2018 IPR013096 Cupin 2, conserved barrel LH59_21010 8c666c5d4c0566125548820be3c3d636 194 Gene3D G3DSA:1.10.260.40 3 78 4.1E-18 T 14-10-2018 LH59_21010 8c666c5d4c0566125548820be3c3d636 194 SUPERFAMILY SSF47413 8 72 6.91E-18 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 LH59_21010 8c666c5d4c0566125548820be3c3d636 194 SMART SM00530 12 67 7.7E-16 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LH59_21010 8c666c5d4c0566125548820be3c3d636 194 Pfam PF01381 Helix-turn-helix 13 67 4.7E-15 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LH59_21010 8c666c5d4c0566125548820be3c3d636 194 SUPERFAMILY SSF51182 78 187 1.97E-27 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_21010 8c666c5d4c0566125548820be3c3d636 194 Gene3D G3DSA:2.60.120.10 79 186 3.3E-28 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_03925 7e3830db4dfcf0f3cb5f186e3ea79716 370 SUPERFAMILY SSF54593 7 353 4.65E-82 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_03925 7e3830db4dfcf0f3cb5f186e3ea79716 370 Gene3D G3DSA:3.10.180.10 170 367 3.6E-68 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_03925 7e3830db4dfcf0f3cb5f186e3ea79716 370 Gene3D G3DSA:3.10.180.10 6 164 2.7E-54 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_03925 7e3830db4dfcf0f3cb5f186e3ea79716 370 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 176 286 9.6E-14 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain LH59_03925 7e3830db4dfcf0f3cb5f186e3ea79716 370 PIRSF PIRSF009283 1 367 3.0E-123 T 14-10-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 LH59_03925 7e3830db4dfcf0f3cb5f186e3ea79716 370 Pfam PF14696 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal 8 153 5.6E-65 T 14-10-2018 LH59_03925 7e3830db4dfcf0f3cb5f186e3ea79716 370 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 16 365 2.0E-118 T 14-10-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 LH59_15530 7874f90da2b7ad68ae05fd74135f6bd5 283 Gene3D G3DSA:3.30.1380.10 149 269 5.1E-22 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 LH59_15530 7874f90da2b7ad68ae05fd74135f6bd5 283 SUPERFAMILY SSF55166 151 266 2.88E-20 T 14-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 LH59_15530 7874f90da2b7ad68ae05fd74135f6bd5 283 Pfam PF13539 D-alanyl-D-alanine carboxypeptidase 204 269 3.5E-11 T 14-10-2018 IPR039561 Peptidase M15C GO:0008233 LH59_21130 a45a819d88c3c34be10e5df4d6dcc0ea 221 SUPERFAMILY SSF53474 8 216 2.07E-24 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_21130 a45a819d88c3c34be10e5df4d6dcc0ea 221 Pfam PF12697 Alpha/beta hydrolase family 25 208 1.7E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_21130 a45a819d88c3c34be10e5df4d6dcc0ea 221 Gene3D G3DSA:3.40.50.1820 4 215 1.2E-23 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_14505 9e6fc06182e218b8b6bebef86c8116bc 645 PIRSF PIRSF003167 8 645 1.5E-189 T 14-10-2018 IPR016380 Signal transduction histidine kinase, nitrate/nitrite-sensing GO:0000155|GO:0000160|GO:0004673|GO:0016021 LH59_14505 9e6fc06182e218b8b6bebef86c8116bc 645 Pfam PF00672 HAMP domain 200 247 2.0E-11 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_14505 9e6fc06182e218b8b6bebef86c8116bc 645 Gene3D G3DSA:1.20.120.960 51 170 4.6E-6 T 14-10-2018 LH59_14505 9e6fc06182e218b8b6bebef86c8116bc 645 SMART SM00387 546 641 1.4E-9 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_14505 9e6fc06182e218b8b6bebef86c8116bc 645 SMART SM00065 286 433 3.8E-6 T 14-10-2018 IPR003018 GAF domain GO:0005515 LH59_14505 9e6fc06182e218b8b6bebef86c8116bc 645 Gene3D G3DSA:3.30.565.10 510 639 2.8E-27 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_14505 9e6fc06182e218b8b6bebef86c8116bc 645 Pfam PF13675 Type IV pili methyl-accepting chemotaxis transducer N-term 44 153 4.6E-23 T 14-10-2018 IPR029095 NarX-like, N-terminal LH59_14505 9e6fc06182e218b8b6bebef86c8116bc 645 Gene3D G3DSA:1.10.8.500 199 249 2.4E-5 T 14-10-2018 LH59_14505 9e6fc06182e218b8b6bebef86c8116bc 645 SUPERFAMILY SSF55874 518 638 2.74E-16 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_14505 9e6fc06182e218b8b6bebef86c8116bc 645 SMART SM00304 199 251 7.3E-15 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_14505 9e6fc06182e218b8b6bebef86c8116bc 645 Pfam PF13185 GAF domain 287 424 8.5E-9 T 14-10-2018 IPR003018 GAF domain GO:0005515 LH59_14505 9e6fc06182e218b8b6bebef86c8116bc 645 SUPERFAMILY SSF55781 287 436 1.74E-18 T 14-10-2018 LH59_14505 9e6fc06182e218b8b6bebef86c8116bc 645 Gene3D G3DSA:3.30.450.40 260 436 2.0E-23 T 14-10-2018 IPR029016 GAF-like domain superfamily LH59_14505 9e6fc06182e218b8b6bebef86c8116bc 645 Pfam PF07730 Histidine kinase 440 506 2.8E-13 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 LH59_14505 9e6fc06182e218b8b6bebef86c8116bc 645 SUPERFAMILY SSF158472 200 249 2.62E-10 T 14-10-2018 LH59_14505 9e6fc06182e218b8b6bebef86c8116bc 645 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 554 639 1.2E-8 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_11665 f4cdf3bfe5f289b44521cfec8897c81b 254 Gene3D G3DSA:3.40.1180.10 3 246 9.2E-89 T 14-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 LH59_11665 f4cdf3bfe5f289b44521cfec8897c81b 254 Pfam PF01255 Putative undecaprenyl diphosphate synthase 22 242 1.1E-77 T 14-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 LH59_11665 f4cdf3bfe5f289b44521cfec8897c81b 254 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 15 242 7.2E-85 T 14-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 LH59_11665 f4cdf3bfe5f289b44521cfec8897c81b 254 SUPERFAMILY SSF64005 13 238 1.96E-83 T 14-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 LH59_11665 f4cdf3bfe5f289b44521cfec8897c81b 254 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 15 243 39.348 T 14-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 LH59_11665 f4cdf3bfe5f289b44521cfec8897c81b 254 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 188 205 - T 14-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 LH59_11135 2381bb471e74ac288eb3b2268f1cafd3 542 Gene3D G3DSA:3.60.20.40 362 542 1.7E-65 T 14-10-2018 LH59_11135 2381bb471e74ac288eb3b2268f1cafd3 542 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 136 155 1.6E-42 T 14-10-2018 LH59_11135 2381bb471e74ac288eb3b2268f1cafd3 542 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 234 250 1.6E-42 T 14-10-2018 LH59_11135 2381bb471e74ac288eb3b2268f1cafd3 542 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 412 427 1.6E-42 T 14-10-2018 LH59_11135 2381bb471e74ac288eb3b2268f1cafd3 542 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 357 375 1.6E-42 T 14-10-2018 LH59_11135 2381bb471e74ac288eb3b2268f1cafd3 542 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 263 282 1.6E-42 T 14-10-2018 LH59_11135 2381bb471e74ac288eb3b2268f1cafd3 542 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 118 136 1.6E-42 T 14-10-2018 LH59_11135 2381bb471e74ac288eb3b2268f1cafd3 542 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 381 399 1.6E-42 T 14-10-2018 LH59_11135 2381bb471e74ac288eb3b2268f1cafd3 542 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 436 453 1.6E-42 T 14-10-2018 LH59_11135 2381bb471e74ac288eb3b2268f1cafd3 542 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 43 68 1.6E-42 T 14-10-2018 LH59_11135 2381bb471e74ac288eb3b2268f1cafd3 542 Gene3D G3DSA:1.10.246.130 250 361 1.6E-30 T 14-10-2018 LH59_11135 2381bb471e74ac288eb3b2268f1cafd3 542 Pfam PF01019 Gamma-glutamyltranspeptidase 36 537 3.8E-150 T 14-10-2018 LH59_11135 2381bb471e74ac288eb3b2268f1cafd3 542 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 22 514 5.4E-109 T 14-10-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-4061|MetaCyc: PWY-5826|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7559 LH59_11135 2381bb471e74ac288eb3b2268f1cafd3 542 SUPERFAMILY SSF56235 7 542 8.49E-175 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal LH59_14910 f977712b772a61ca21bc446d00b78b96 462 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 152 160 - T 14-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site LH59_14910 f977712b772a61ca21bc446d00b78b96 462 SMART SM00487 23 220 4.6E-62 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain LH59_14910 f977712b772a61ca21bc446d00b78b96 462 Gene3D G3DSA:3.40.50.300 2 210 1.5E-75 T 14-10-2018 LH59_14910 f977712b772a61ca21bc446d00b78b96 462 Pfam PF00270 DEAD/DEAH box helicase 28 195 4.2E-50 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 LH59_14910 f977712b772a61ca21bc446d00b78b96 462 SUPERFAMILY SSF52540 73 359 8.65E-70 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_14910 f977712b772a61ca21bc446d00b78b96 462 Pfam PF00271 Helicase conserved C-terminal domain 236 336 3.8E-23 T 14-10-2018 IPR001650 Helicase, C-terminal LH59_14910 f977712b772a61ca21bc446d00b78b96 462 Gene3D G3DSA:3.30.70.330 386 460 2.1E-19 T 14-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily LH59_14910 f977712b772a61ca21bc446d00b78b96 462 Pfam PF03880 DbpA RNA binding domain 387 457 1.2E-21 T 14-10-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain LH59_14910 f977712b772a61ca21bc446d00b78b96 462 SMART SM00490 256 337 2.3E-24 T 14-10-2018 IPR001650 Helicase, C-terminal LH59_14910 f977712b772a61ca21bc446d00b78b96 462 Gene3D G3DSA:3.40.50.300 214 381 5.9E-40 T 14-10-2018 LH59_06855 844de4b3257a108c89eafa50c113f1d7 591 SUPERFAMILY SSF53335 359 579 1.02E-41 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_06855 844de4b3257a108c89eafa50c113f1d7 591 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 406 417 - T 14-10-2018 IPR000241 Putative RNA methylase domain LH59_06855 844de4b3257a108c89eafa50c113f1d7 591 Pfam PF02926 THUMP domain 247 364 6.7E-9 T 14-10-2018 IPR004114 THUMP domain GO:0003723 LH59_06855 844de4b3257a108c89eafa50c113f1d7 591 Gene3D G3DSA:3.40.50.150 380 576 6.1E-131 T 14-10-2018 LH59_06855 844de4b3257a108c89eafa50c113f1d7 591 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 511 517 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 LH59_06855 844de4b3257a108c89eafa50c113f1d7 591 SMART SM00981 267 365 1.4E-13 T 14-10-2018 IPR004114 THUMP domain GO:0003723 LH59_06855 844de4b3257a108c89eafa50c113f1d7 591 Pfam PF01170 Putative RNA methylase family UPF0020 373 577 2.8E-47 T 14-10-2018 IPR000241 Putative RNA methylase domain LH59_06855 844de4b3257a108c89eafa50c113f1d7 591 Gene3D G3DSA:3.30.2130.30 216 462 6.1E-131 T 14-10-2018 LH59_15760 f1d7804872834dca01fc1fa80dacd805 323 SUPERFAMILY SSF53850 25 300 7.53E-62 T 14-10-2018 LH59_15760 f1d7804872834dca01fc1fa80dacd805 323 Gene3D G3DSA:3.40.190.10 127 240 1.9E-62 T 14-10-2018 LH59_15760 f1d7804872834dca01fc1fa80dacd805 323 PIRSF PIRSF002825 15 319 3.2E-49 T 14-10-2018 IPR026045 Ferric binding protein LH59_15760 f1d7804872834dca01fc1fa80dacd805 323 Pfam PF13343 Bacterial extracellular solute-binding protein 75 288 1.7E-30 T 14-10-2018 LH59_15760 f1d7804872834dca01fc1fa80dacd805 323 Gene3D G3DSA:3.40.190.10 31 290 1.9E-62 T 14-10-2018 LH59_22900 4530e7caed8275e46ec8ea84d0b0ea98 195 Pfam PF12804 MobA-like NTP transferase domain 3 156 3.6E-34 T 14-10-2018 IPR025877 MobA-like NTP transferase LH59_22900 4530e7caed8275e46ec8ea84d0b0ea98 195 TIGRFAM TIGR02665 molyb_mobA: molybdenum cofactor guanylyltransferase 2 187 5.3E-63 T 14-10-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 LH59_22900 4530e7caed8275e46ec8ea84d0b0ea98 195 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 1 189 25.957 T 14-10-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 LH59_22900 4530e7caed8275e46ec8ea84d0b0ea98 195 Gene3D G3DSA:3.90.550.10 1 194 7.4E-53 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases LH59_22900 4530e7caed8275e46ec8ea84d0b0ea98 195 SUPERFAMILY SSF53448 2 186 2.05E-33 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases LH59_17815 71d8579d9f1ae6111ebdb5d9991c6ccf 294 Gene3D G3DSA:3.40.190.10 161 259 4.8E-58 T 14-10-2018 LH59_17815 71d8579d9f1ae6111ebdb5d9991c6ccf 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 5.8E-19 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_17815 71d8579d9f1ae6111ebdb5d9991c6ccf 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 6.1E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_17815 71d8579d9f1ae6111ebdb5d9991c6ccf 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 6.1E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_17815 71d8579d9f1ae6111ebdb5d9991c6ccf 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 6.1E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_17815 71d8579d9f1ae6111ebdb5d9991c6ccf 294 Gene3D G3DSA:1.10.10.10 4 93 8.8E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_17815 71d8579d9f1ae6111ebdb5d9991c6ccf 294 SUPERFAMILY SSF53850 92 292 1.18E-38 T 14-10-2018 LH59_17815 71d8579d9f1ae6111ebdb5d9991c6ccf 294 Gene3D G3DSA:3.40.190.10 101 286 4.8E-58 T 14-10-2018 LH59_17815 71d8579d9f1ae6111ebdb5d9991c6ccf 294 SUPERFAMILY SSF46785 6 111 1.49E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_17815 71d8579d9f1ae6111ebdb5d9991c6ccf 294 Pfam PF03466 LysR substrate binding domain 90 290 1.2E-36 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_04575 cb5586049a9fafa125bb94a740d9a04c 349 Pfam PF00586 AIR synthase related protein, N-terminal domain 60 166 7.2E-14 T 14-10-2018 IPR016188 PurM-like, N-terminal domain LH59_04575 cb5586049a9fafa125bb94a740d9a04c 349 Pfam PF02769 AIR synthase related protein, C-terminal domain 178 341 4.4E-37 T 14-10-2018 IPR010918 PurM-like, C-terminal domain LH59_04575 cb5586049a9fafa125bb94a740d9a04c 349 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 9 338 6.0E-136 T 14-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 LH59_04575 cb5586049a9fafa125bb94a740d9a04c 349 Gene3D G3DSA:3.30.1330.10 8 172 1.6E-67 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily LH59_04575 cb5586049a9fafa125bb94a740d9a04c 349 SUPERFAMILY SSF55326 9 172 1.43E-52 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily LH59_04575 cb5586049a9fafa125bb94a740d9a04c 349 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 9 348 46.386 T 14-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 LH59_04575 cb5586049a9fafa125bb94a740d9a04c 349 SUPERFAMILY SSF56042 173 345 1.21E-58 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily LH59_04575 cb5586049a9fafa125bb94a740d9a04c 349 Gene3D G3DSA:3.90.650.10 174 349 3.7E-68 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily LH59_27385 5057ca4e924e1042a9ae8e0744e1e907 342 SUPERFAMILY SSF53383 2 336 4.92E-60 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_27385 5057ca4e924e1042a9ae8e0744e1e907 342 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 9 334 1.6E-55 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase LH59_27385 5057ca4e924e1042a9ae8e0744e1e907 342 Gene3D G3DSA:3.40.640.10 1 223 1.9E-54 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_27385 5057ca4e924e1042a9ae8e0744e1e907 342 PIRSF PIRSF000390 1 342 2.2E-56 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase LH59_27385 5057ca4e924e1042a9ae8e0744e1e907 342 Gene3D G3DSA:3.90.1150.10 225 341 1.1E-12 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_01390 34645ba2e0d8b0228d7a10cce365b1e9 417 Gene3D G3DSA:1.20.1600.10 12 417 1.2E-72 T 14-10-2018 LH59_01390 34645ba2e0d8b0228d7a10cce365b1e9 417 Pfam PF02321 Outer membrane efflux protein 242 416 8.3E-22 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 LH59_01390 34645ba2e0d8b0228d7a10cce365b1e9 417 Pfam PF02321 Outer membrane efflux protein 43 217 3.2E-24 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 LH59_01390 34645ba2e0d8b0228d7a10cce365b1e9 417 SUPERFAMILY SSF56954 3 416 4.32E-77 T 14-10-2018 LH59_24965 2f8dd36b5b9b3f9633529ce502ac28a4 200 SUPERFAMILY SSF48498 90 196 2.8E-7 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily LH59_24965 2f8dd36b5b9b3f9633529ce502ac28a4 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 2.2E-16 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_24965 2f8dd36b5b9b3f9633529ce502ac28a4 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 2.4E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_24965 2f8dd36b5b9b3f9633529ce502ac28a4 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 2.4E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_24965 2f8dd36b5b9b3f9633529ce502ac28a4 200 SUPERFAMILY SSF46689 5 83 6.14E-18 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_24965 2f8dd36b5b9b3f9633529ce502ac28a4 200 Gene3D G3DSA:1.10.357.10 4 199 1.5E-36 T 14-10-2018 LH59_07505 7711f7684f1edbeb18804d95e92177d7 554 Pfam PF00171 Aldehyde dehydrogenase family 90 501 4.4E-36 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 LH59_07505 7711f7684f1edbeb18804d95e92177d7 554 TIGRFAM TIGR02288 PaaN_2: phenylacetic acid degradation protein paaN 3 554 2.4E-292 T 14-10-2018 IPR011975 Phenylacetic acid degradation protein PaaN2 LH59_07505 7711f7684f1edbeb18804d95e92177d7 554 SUPERFAMILY SSF53720 72 532 1.44E-59 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 LH59_07505 7711f7684f1edbeb18804d95e92177d7 554 Gene3D G3DSA:3.40.605.10 90 315 1.2E-27 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 LH59_07505 7711f7684f1edbeb18804d95e92177d7 554 Gene3D G3DSA:3.40.309.10 316 524 6.0E-25 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 LH59_06180 28e521645d409d0709483c129a8a87a2 739 Pfam PF07715 TonB-dependent Receptor Plug Domain 71 168 1.0E-16 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_06180 28e521645d409d0709483c129a8a87a2 739 Gene3D G3DSA:2.40.170.20 183 739 4.2E-118 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_06180 28e521645d409d0709483c129a8a87a2 739 Gene3D G3DSA:2.170.130.10 52 180 1.1E-38 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily LH59_06180 28e521645d409d0709483c129a8a87a2 739 Pfam PF00593 TonB dependent receptor 250 738 2.8E-53 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_06180 28e521645d409d0709483c129a8a87a2 739 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 72 737 2.9E-80 T 14-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 LH59_06180 28e521645d409d0709483c129a8a87a2 739 SUPERFAMILY SSF56935 32 739 5.04E-121 T 14-10-2018 LH59_02440 0fba7c79b31e46632146f77e9edb5c1f 399 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 145 172 - T 14-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 LH59_02440 0fba7c79b31e46632146f77e9edb5c1f 399 Gene3D G3DSA:3.40.50.720 100 288 4.6E-105 T 14-10-2018 LH59_02440 0fba7c79b31e46632146f77e9edb5c1f 399 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 220 236 - T 14-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site LH59_02440 0fba7c79b31e46632146f77e9edb5c1f 399 SUPERFAMILY SSF55021 325 396 5.73E-12 T 14-10-2018 LH59_02440 0fba7c79b31e46632146f77e9edb5c1f 399 Gene3D G3DSA:3.30.70.260 319 399 4.7E-23 T 14-10-2018 LH59_02440 0fba7c79b31e46632146f77e9edb5c1f 399 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 111 285 5.7E-54 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 LH59_02440 0fba7c79b31e46632146f77e9edb5c1f 399 SUPERFAMILY SSF51735 99 286 7.22E-60 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_02440 0fba7c79b31e46632146f77e9edb5c1f 399 Gene3D G3DSA:3.40.50.720 6 303 4.6E-105 T 14-10-2018 LH59_02440 0fba7c79b31e46632146f77e9edb5c1f 399 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 317 1.5E-35 T 14-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 LH59_02440 0fba7c79b31e46632146f77e9edb5c1f 399 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 191 213 - T 14-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site LH59_02440 0fba7c79b31e46632146f77e9edb5c1f 399 SUPERFAMILY SSF52283 4 125 2.34E-38 T 14-10-2018 LH59_15975 3db4dcf376ebc11765c10f882b2e274d 287 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 1.1E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_15975 3db4dcf376ebc11765c10f882b2e274d 287 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 1.1E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_15975 3db4dcf376ebc11765c10f882b2e274d 287 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.1E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_15975 3db4dcf376ebc11765c10f882b2e274d 287 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 12 194 1.7E-4 T 14-10-2018 LH59_15975 3db4dcf376ebc11765c10f882b2e274d 287 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LH59_15975 3db4dcf376ebc11765c10f882b2e274d 287 Pfam PF00106 short chain dehydrogenase 15 198 7.7E-48 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_15975 3db4dcf376ebc11765c10f882b2e274d 287 SUPERFAMILY SSF51735 10 255 2.12E-62 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_15975 3db4dcf376ebc11765c10f882b2e274d 287 Gene3D G3DSA:3.40.50.720 8 287 1.7E-74 T 14-10-2018 LH59_15975 3db4dcf376ebc11765c10f882b2e274d 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 4.2E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_15975 3db4dcf376ebc11765c10f882b2e274d 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 4.2E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_15975 3db4dcf376ebc11765c10f882b2e274d 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 4.2E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_15975 3db4dcf376ebc11765c10f882b2e274d 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 4.2E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_15975 3db4dcf376ebc11765c10f882b2e274d 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 4.2E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_07635 e02635cb31129b799cc4eeb76bc678b3 1017 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 1015 17.346 T 14-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 LH59_07635 e02635cb31129b799cc4eeb76bc678b3 1017 Pfam PF00009 Elongation factor Tu GTP binding domain 523 678 1.9E-34 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_07635 e02635cb31129b799cc4eeb76bc678b3 1017 SUPERFAMILY SSF50447 691 773 1.33E-25 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily LH59_07635 e02635cb31129b799cc4eeb76bc678b3 1017 Gene3D G3DSA:2.40.30.10 690 809 6.2E-39 T 14-10-2018 LH59_07635 e02635cb31129b799cc4eeb76bc678b3 1017 Pfam PF08364 Bacterial translation initiation factor IF-2 associated region 60 97 3.2E-15 T 14-10-2018 IPR013575 Initiation factor 2 associated domain, bacterial LH59_07635 e02635cb31129b799cc4eeb76bc678b3 1017 Gene3D G3DSA:3.40.50.300 516 689 4.7E-70 T 14-10-2018 LH59_07635 e02635cb31129b799cc4eeb76bc678b3 1017 SUPERFAMILY SSF52156 796 924 3.4E-37 T 14-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily LH59_07635 e02635cb31129b799cc4eeb76bc678b3 1017 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 435 1017 5.4E-252 T 14-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 LH59_07635 e02635cb31129b799cc4eeb76bc678b3 1017 ProSitePatterns PS01176 Initiation factor 2 signature. 968 990 - T 14-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 LH59_07635 e02635cb31129b799cc4eeb76bc678b3 1017 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 1 50 7.0E-9 T 14-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal LH59_07635 e02635cb31129b799cc4eeb76bc678b3 1017 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 441 491 3.9E-15 T 14-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal LH59_07635 e02635cb31129b799cc4eeb76bc678b3 1017 SUPERFAMILY SSF52540 513 687 1.52E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_07635 e02635cb31129b799cc4eeb76bc678b3 1017 Gene3D G3DSA:3.30.56.50 3 51 2.3E-5 T 14-10-2018 LH59_07635 e02635cb31129b799cc4eeb76bc678b3 1017 SUPERFAMILY SSF50447 919 1015 7.69E-32 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily LH59_07635 e02635cb31129b799cc4eeb76bc678b3 1017 SUPERFAMILY SSF46955 4 51 3.84E-9 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily LH59_07635 e02635cb31129b799cc4eeb76bc678b3 1017 Gene3D G3DSA:3.40.50.10050 811 918 4.1E-38 T 14-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily LH59_07635 e02635cb31129b799cc4eeb76bc678b3 1017 Pfam PF11987 Translation-initiation factor 2 803 907 1.9E-36 T 14-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 LH59_07635 e02635cb31129b799cc4eeb76bc678b3 1017 Gene3D G3DSA:2.40.30.10 919 1016 3.0E-29 T 14-10-2018 LH59_07635 e02635cb31129b799cc4eeb76bc678b3 1017 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 522 677 1.1E-31 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 LH59_17995 49b471b7e918df0989660c8c39c8ec44 304 SUPERFAMILY SSF53850 92 297 4.03E-37 T 14-10-2018 LH59_17995 49b471b7e918df0989660c8c39c8ec44 304 Gene3D G3DSA:3.40.190.290 92 300 1.3E-34 T 14-10-2018 LH59_17995 49b471b7e918df0989660c8c39c8ec44 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.8E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_17995 49b471b7e918df0989660c8c39c8ec44 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.8E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_17995 49b471b7e918df0989660c8c39c8ec44 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.8E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_17995 49b471b7e918df0989660c8c39c8ec44 304 Gene3D G3DSA:1.10.10.10 1 90 4.4E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_17995 49b471b7e918df0989660c8c39c8ec44 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 59 7.3E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_17995 49b471b7e918df0989660c8c39c8ec44 304 Pfam PF03466 LysR substrate binding domain 91 292 1.2E-37 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_17995 49b471b7e918df0989660c8c39c8ec44 304 SUPERFAMILY SSF46785 2 80 3.13E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_10920 b002144fb9f4dfb9d02653968a2f40ce 477 Gene3D G3DSA:3.40.605.10 22 468 6.3E-176 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 LH59_10920 b002144fb9f4dfb9d02653968a2f40ce 477 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 246 253 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 LH59_10920 b002144fb9f4dfb9d02653968a2f40ce 477 Pfam PF00171 Aldehyde dehydrogenase family 11 473 1.4E-159 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 LH59_10920 b002144fb9f4dfb9d02653968a2f40ce 477 Gene3D G3DSA:3.40.309.10 250 442 6.3E-176 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 LH59_10920 b002144fb9f4dfb9d02653968a2f40ce 477 SUPERFAMILY SSF53720 2 476 6.94E-159 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 LH59_23715 337d452eb39f0a8c325463f61c944d61 667 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 290 344 - T 14-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_23715 337d452eb39f0a8c325463f61c944d61 667 Gene3D G3DSA:1.20.210.10 17 575 1.5E-190 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_23715 337d452eb39f0a8c325463f61c944d61 667 SUPERFAMILY SSF81442 53 570 1.57E-177 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_23715 337d452eb39f0a8c325463f61c944d61 667 TIGRFAM TIGR02843 CyoB: cytochrome o ubiquinol oxidase, subunit I 12 656 0.0 T 14-10-2018 IPR014207 Cytochrome o ubiquinol oxidase, subunit I GO:0016682|GO:0055114 MetaCyc: PWY-7544 LH59_23715 337d452eb39f0a8c325463f61c944d61 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 208 226 1.0E-94 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_23715 337d452eb39f0a8c325463f61c944d61 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 358 379 1.0E-94 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_23715 337d452eb39f0a8c325463f61c944d61 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 471 492 1.0E-94 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_23715 337d452eb39f0a8c325463f61c944d61 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 176 188 1.0E-94 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_23715 337d452eb39f0a8c325463f61c944d61 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 288 309 1.0E-94 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_23715 337d452eb39f0a8c325463f61c944d61 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 134 158 1.0E-94 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_23715 337d452eb39f0a8c325463f61c944d61 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 421 440 1.0E-94 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_23715 337d452eb39f0a8c325463f61c944d61 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 57 82 1.0E-94 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_23715 337d452eb39f0a8c325463f61c944d61 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 107 130 1.0E-94 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_23715 337d452eb39f0a8c325463f61c944d61 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 334 349 1.0E-94 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_23715 337d452eb39f0a8c325463f61c944d61 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 393 411 1.0E-94 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_23715 337d452eb39f0a8c325463f61c944d61 667 PRINTS PR01165 Cytochrome c oxidase subunit I signature 237 256 1.0E-94 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_23715 337d452eb39f0a8c325463f61c944d61 667 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 66 514 3.2E-136 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_01850 5f6e73fe5a69016a352a8b846b23fa4b 433 SUPERFAMILY SSF50685 54 426 1.08E-120 T 14-10-2018 IPR036908 RlpA-like domain superfamily LH59_01850 5f6e73fe5a69016a352a8b846b23fa4b 433 Gene3D G3DSA:2.40.240.50 166 328 8.4E-124 T 14-10-2018 LH59_01850 5f6e73fe5a69016a352a8b846b23fa4b 433 Gene3D G3DSA:2.40.40.10 69 425 8.4E-124 T 14-10-2018 IPR036908 RlpA-like domain superfamily LH59_01850 5f6e73fe5a69016a352a8b846b23fa4b 433 Pfam PF06725 3D domain 349 422 3.7E-23 T 14-10-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 LH59_01850 5f6e73fe5a69016a352a8b846b23fa4b 433 PIRSF PIRSF019422 1 432 1.8E-124 T 14-10-2018 IPR026044 Membrane-bound lytic murein transglycosylase A LH59_01850 5f6e73fe5a69016a352a8b846b23fa4b 433 Pfam PF03562 MltA specific insert domain 75 326 4.6E-80 T 14-10-2018 IPR005300 Lytic transglycosylase MltA, domain B GO:0004553 LH59_01850 5f6e73fe5a69016a352a8b846b23fa4b 433 SMART SM00925 167 326 8.0E-91 T 14-10-2018 IPR005300 Lytic transglycosylase MltA, domain B GO:0004553 LH59_06800 122a4c06a03d08cd87f3e2cf8b8347bb 428 PRINTS PR00148 Enolase signature 335 349 3.0E-44 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LH59_06800 122a4c06a03d08cd87f3e2cf8b8347bb 428 PRINTS PR00148 Enolase signature 37 51 3.0E-44 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LH59_06800 122a4c06a03d08cd87f3e2cf8b8347bb 428 PRINTS PR00148 Enolase signature 312 323 3.0E-44 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LH59_06800 122a4c06a03d08cd87f3e2cf8b8347bb 428 PRINTS PR00148 Enolase signature 161 174 3.0E-44 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LH59_06800 122a4c06a03d08cd87f3e2cf8b8347bb 428 PRINTS PR00148 Enolase signature 107 123 3.0E-44 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LH59_06800 122a4c06a03d08cd87f3e2cf8b8347bb 428 PRINTS PR00148 Enolase signature 364 381 3.0E-44 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LH59_06800 122a4c06a03d08cd87f3e2cf8b8347bb 428 PIRSF PIRSF001400 1 426 1.8E-187 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LH59_06800 122a4c06a03d08cd87f3e2cf8b8347bb 428 Pfam PF03952 Enolase, N-terminal domain 4 133 3.2E-56 T 14-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LH59_06800 122a4c06a03d08cd87f3e2cf8b8347bb 428 Gene3D G3DSA:3.20.20.120 128 428 1.4E-129 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily LH59_06800 122a4c06a03d08cd87f3e2cf8b8347bb 428 SMART SM01192 139 426 8.5E-218 T 14-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LH59_06800 122a4c06a03d08cd87f3e2cf8b8347bb 428 SUPERFAMILY SSF51604 139 427 2.97E-128 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily LH59_06800 122a4c06a03d08cd87f3e2cf8b8347bb 428 SMART SM01193 4 134 1.8E-89 T 14-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LH59_06800 122a4c06a03d08cd87f3e2cf8b8347bb 428 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 426 6.6E-205 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LH59_06800 122a4c06a03d08cd87f3e2cf8b8347bb 428 Gene3D G3DSA:3.30.390.10 1 127 4.9E-54 T 14-10-2018 IPR029017 Enolase-like, N-terminal LH59_06800 122a4c06a03d08cd87f3e2cf8b8347bb 428 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 424 5.0E-130 T 14-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LH59_06800 122a4c06a03d08cd87f3e2cf8b8347bb 428 SUPERFAMILY SSF54826 4 136 5.96E-54 T 14-10-2018 LH59_06800 122a4c06a03d08cd87f3e2cf8b8347bb 428 ProSitePatterns PS00164 Enolase signature. 335 348 - T 14-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_06800 122a4c06a03d08cd87f3e2cf8b8347bb 428 Hamap MF_00318 Enolase [eno]. 2 412 44.309 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LH59_19690 913d93daa4aabe884a3694cf0daf1272 295 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 252 2.0E-48 T 14-10-2018 LH59_19690 913d93daa4aabe884a3694cf0daf1272 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 4.0E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_19690 913d93daa4aabe884a3694cf0daf1272 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 4.0E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_19690 913d93daa4aabe884a3694cf0daf1272 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 4.0E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_19690 913d93daa4aabe884a3694cf0daf1272 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 4.0E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_19690 913d93daa4aabe884a3694cf0daf1272 295 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 4.0E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_19690 913d93daa4aabe884a3694cf0daf1272 295 Gene3D G3DSA:3.40.50.720 1 285 2.7E-77 T 14-10-2018 LH59_19690 913d93daa4aabe884a3694cf0daf1272 295 SUPERFAMILY SSF51735 8 254 1.39E-70 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_27885 9ddbcac7df570861b252773685a9a9e3 109 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 109 23.929 T 14-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_27885 9ddbcac7df570861b252773685a9a9e3 109 SUPERFAMILY SSF54843 1 107 7.98E-39 T 14-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 LH59_27885 9ddbcac7df570861b252773685a9a9e3 109 Gene3D G3DSA:3.90.470.10 1 109 7.6E-41 T 14-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 LH59_27885 9ddbcac7df570861b252773685a9a9e3 109 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 14-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27885 9ddbcac7df570861b252773685a9a9e3 109 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 107 3.9E-43 T 14-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_27885 9ddbcac7df570861b252773685a9a9e3 109 Pfam PF00237 Ribosomal protein L22p/L17e 7 107 6.8E-35 T 14-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 LH59_14925 aa658451515aeec7e54deaf36be88ccb 157 Pfam PF12802 MarR family 35 94 2.3E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_14925 aa658451515aeec7e54deaf36be88ccb 157 SUPERFAMILY SSF46785 8 144 3.67E-30 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_14925 aa658451515aeec7e54deaf36be88ccb 157 Gene3D G3DSA:1.10.10.10 1 145 1.7E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_14925 aa658451515aeec7e54deaf36be88ccb 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 71 86 1.0E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_14925 aa658451515aeec7e54deaf36be88ccb 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 54 70 1.0E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_14925 aa658451515aeec7e54deaf36be88ccb 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 90 106 1.0E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_14925 aa658451515aeec7e54deaf36be88ccb 157 SMART SM00347 29 130 2.0E-18 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_05640 21c502819b75ec696677782c040d192d 571 SUPERFAMILY SSF52467 187 361 4.91E-63 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily LH59_05640 21c502819b75ec696677782c040d192d 571 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 3 168 5.6E-60 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 LH59_05640 21c502819b75ec696677782c040d192d 571 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 393 541 9.7E-48 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 LH59_05640 21c502819b75ec696677782c040d192d 571 SUPERFAMILY SSF52518 2 175 1.05E-64 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold LH59_05640 21c502819b75ec696677782c040d192d 571 Gene3D G3DSA:3.40.50.970 363 570 4.4E-64 T 14-10-2018 LH59_05640 21c502819b75ec696677782c040d192d 571 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 3 565 1.3E-246 T 14-10-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 LH59_05640 21c502819b75ec696677782c040d192d 571 Gene3D G3DSA:3.40.50.1220 187 359 2.0E-60 T 14-10-2018 LH59_05640 21c502819b75ec696677782c040d192d 571 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 194 330 6.9E-45 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 LH59_05640 21c502819b75ec696677782c040d192d 571 SUPERFAMILY SSF52518 371 566 4.65E-66 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold LH59_05640 21c502819b75ec696677782c040d192d 571 Gene3D G3DSA:3.40.50.970 1 178 4.0E-72 T 14-10-2018 LH59_09980 e826d489410d692c2f3116a0e9dbda5c 400 Gene3D G3DSA:3.40.47.10 9 240 6.9E-28 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_09980 e826d489410d692c2f3116a0e9dbda5c 400 SUPERFAMILY SSF53901 206 398 1.12E-42 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_09980 e826d489410d692c2f3116a0e9dbda5c 400 SUPERFAMILY SSF53901 10 235 5.24E-34 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_09980 e826d489410d692c2f3116a0e9dbda5c 400 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 93 233 4.5E-20 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal LH59_09980 e826d489410d692c2f3116a0e9dbda5c 400 SMART SM00825 Beta-ketoacyl synthase 10 400 1.0E-7 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain LH59_09980 e826d489410d692c2f3116a0e9dbda5c 400 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 242 337 2.0E-22 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal LH59_09980 e826d489410d692c2f3116a0e9dbda5c 400 Gene3D G3DSA:3.40.47.10 245 395 1.9E-37 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_09980 e826d489410d692c2f3116a0e9dbda5c 400 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 150 166 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site LH59_00440 18212aceba93d687baa4f1574a44c1b1 128 Pfam PF06803 Protein of unknown function (DUF1232) 34 69 1.0E-12 T 14-10-2018 IPR010652 Domain of unknown function DUF1232 MetaCyc: PWY-7511 LH59_04695 81a47fec42b6f8e3f5a68fb4ae192110 284 Pfam PF00551 Formyl transferase 89 265 3.4E-39 T 14-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 LH59_04695 81a47fec42b6f8e3f5a68fb4ae192110 284 PIRSF PIRSF036480 3 284 2.8E-113 T 14-10-2018 LH59_04695 81a47fec42b6f8e3f5a68fb4ae192110 284 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 7 283 3.1E-106 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 LH59_04695 81a47fec42b6f8e3f5a68fb4ae192110 284 Gene3D G3DSA:3.40.50.170 88 283 7.3E-72 T 14-10-2018 LH59_04695 81a47fec42b6f8e3f5a68fb4ae192110 284 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 3 283 48.301 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 LH59_04695 81a47fec42b6f8e3f5a68fb4ae192110 284 SUPERFAMILY SSF53328 89 284 4.71E-63 T 14-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 LH59_04695 81a47fec42b6f8e3f5a68fb4ae192110 284 SUPERFAMILY SSF55021 2 87 1.25E-19 T 14-10-2018 LH59_04695 81a47fec42b6f8e3f5a68fb4ae192110 284 Gene3D G3DSA:3.30.70.260 1 87 1.1E-30 T 14-10-2018 LH59_04695 81a47fec42b6f8e3f5a68fb4ae192110 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 40 52 6.8E-58 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 LH59_04695 81a47fec42b6f8e3f5a68fb4ae192110 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 235 257 6.8E-58 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 LH59_04695 81a47fec42b6f8e3f5a68fb4ae192110 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 8 34 6.8E-58 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 LH59_04695 81a47fec42b6f8e3f5a68fb4ae192110 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 89 111 6.8E-58 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 LH59_04695 81a47fec42b6f8e3f5a68fb4ae192110 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 257 282 6.8E-58 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 LH59_04695 81a47fec42b6f8e3f5a68fb4ae192110 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 111 138 6.8E-58 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 LH59_04695 81a47fec42b6f8e3f5a68fb4ae192110 284 Pfam PF13740 ACT domain 7 81 3.6E-7 T 14-10-2018 LH59_27570 272b092ad6360bfc825f0ed3b3636d4e 252 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 65 2.3E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_27570 272b092ad6360bfc825f0ed3b3636d4e 252 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 49 2.3E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_27570 272b092ad6360bfc825f0ed3b3636d4e 252 SMART SM00895 99 226 1.4E-21 T 14-10-2018 IPR011711 GntR, C-terminal LH59_27570 272b092ad6360bfc825f0ed3b3636d4e 252 Gene3D G3DSA:1.20.120.530 84 241 1.5E-30 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_27570 272b092ad6360bfc825f0ed3b3636d4e 252 Pfam PF07729 FCD domain 99 225 2.8E-23 T 14-10-2018 IPR011711 GntR, C-terminal LH59_27570 272b092ad6360bfc825f0ed3b3636d4e 252 SMART SM00345 16 75 2.8E-15 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_27570 272b092ad6360bfc825f0ed3b3636d4e 252 SUPERFAMILY SSF46785 9 79 3.32E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_27570 272b092ad6360bfc825f0ed3b3636d4e 252 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 75 2.6E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_27570 272b092ad6360bfc825f0ed3b3636d4e 252 Gene3D G3DSA:1.10.10.10 7 81 1.6E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_27570 272b092ad6360bfc825f0ed3b3636d4e 252 SUPERFAMILY SSF48008 96 233 8.63E-25 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_19855 b7f739907e983fc8aa01779bff41e24b 179 Gene3D G3DSA:1.10.10.10 4 166 2.9E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_19855 b7f739907e983fc8aa01779bff41e24b 179 SUPERFAMILY SSF46785 28 164 6.52E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_19855 b7f739907e983fc8aa01779bff41e24b 179 Pfam PF12802 MarR family 55 113 4.5E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_19855 b7f739907e983fc8aa01779bff41e24b 179 SMART SM00347 50 150 7.1E-6 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_14390 faba180a056d0d2eacda89771c6045e2 300 Pfam PF00701 Dihydrodipicolinate synthetase family 6 286 5.0E-51 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_14390 faba180a056d0d2eacda89771c6045e2 300 SMART SM01130 4 296 4.0E-80 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_14390 faba180a056d0d2eacda89771c6045e2 300 SUPERFAMILY SSF51569 4 289 5.13E-79 T 14-10-2018 LH59_14390 faba180a056d0d2eacda89771c6045e2 300 PRINTS PR00146 Dihydrodipicolinate synthase signature 38 59 5.0E-11 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_14390 faba180a056d0d2eacda89771c6045e2 300 PRINTS PR00146 Dihydrodipicolinate synthase signature 74 92 5.0E-11 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_14390 faba180a056d0d2eacda89771c6045e2 300 PRINTS PR00146 Dihydrodipicolinate synthase signature 131 148 5.0E-11 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_14390 faba180a056d0d2eacda89771c6045e2 300 Gene3D G3DSA:3.20.20.70 1 294 6.6E-81 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_14390 faba180a056d0d2eacda89771c6045e2 300 PIRSF PIRSF001365 1 294 2.4E-70 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_06170 010864a35d77e7515208053adb76dbec 494 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 10 478 8.2E-140 T 14-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 LH59_06170 010864a35d77e7515208053adb76dbec 494 Pfam PF00361 Proton-conducting membrane transporter 127 429 1.3E-74 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06170 010864a35d77e7515208053adb76dbec 494 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 310 322 7.0E-5 T 14-10-2018 LH59_06170 010864a35d77e7515208053adb76dbec 494 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 218 239 7.0E-5 T 14-10-2018 LH59_06170 010864a35d77e7515208053adb76dbec 494 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 423 442 7.0E-5 T 14-10-2018 LH59_06170 010864a35d77e7515208053adb76dbec 494 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 74 99 7.0E-5 T 14-10-2018 LH59_06170 010864a35d77e7515208053adb76dbec 494 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 6 481 18.375 T 14-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 LH59_26760 11ba214a7eea254b1954721903313e4d 347 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 9 340 1.5E-153 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 LH59_26760 11ba214a7eea254b1954721903313e4d 347 Gene3D G3DSA:3.30.420.40 159 322 1.8E-130 T 14-10-2018 LH59_26760 11ba214a7eea254b1954721903313e4d 347 SUPERFAMILY SSF53067 156 337 8.96E-49 T 14-10-2018 LH59_26760 11ba214a7eea254b1954721903313e4d 347 Gene3D G3DSA:3.30.420.40 13 332 1.8E-130 T 14-10-2018 LH59_26760 11ba214a7eea254b1954721903313e4d 347 SUPERFAMILY SSF53067 9 153 4.65E-37 T 14-10-2018 LH59_26760 11ba214a7eea254b1954721903313e4d 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 53 71 9.0E-62 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 LH59_26760 11ba214a7eea254b1954721903313e4d 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 137 156 9.0E-62 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 LH59_26760 11ba214a7eea254b1954721903313e4d 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 73 96 9.0E-62 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 LH59_26760 11ba214a7eea254b1954721903313e4d 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 192 212 9.0E-62 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 LH59_26760 11ba214a7eea254b1954721903313e4d 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 305 331 9.0E-62 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 LH59_26760 11ba214a7eea254b1954721903313e4d 347 Pfam PF06723 MreB/Mbl protein 11 340 3.3E-147 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 LH59_26760 11ba214a7eea254b1954721903313e4d 347 Gene3D G3DSA:3.90.640.10 191 264 1.8E-130 T 14-10-2018 LH59_25525 66c2fa1bb1d5a92e9fe7b60c34a737b2 447 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 360 380 - T 14-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 LH59_25525 66c2fa1bb1d5a92e9fe7b60c34a737b2 447 TIGRFAM TIGR03173 pbuX: xanthine permease 25 444 1.3E-126 T 14-10-2018 IPR017588 Uric acid permease UacT-like GO:0016021|GO:0022857|GO:0055085 LH59_25525 66c2fa1bb1d5a92e9fe7b60c34a737b2 447 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 17 440 5.2E-120 T 14-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 LH59_25525 66c2fa1bb1d5a92e9fe7b60c34a737b2 447 Pfam PF00860 Permease family 22 413 1.1E-91 T 14-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 LH59_07930 7592af6fa87949fffef9756492356aa6 430 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 134 141 - T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 LH59_07930 7592af6fa87949fffef9756492356aa6 430 Gene3D G3DSA:3.40.50.1370 218 385 2.6E-101 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 LH59_07930 7592af6fa87949fffef9756492356aa6 430 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 90 229 8.9E-42 T 14-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 LH59_07930 7592af6fa87949fffef9756492356aa6 430 SUPERFAMILY SSF53671 90 399 5.24E-89 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 LH59_07930 7592af6fa87949fffef9756492356aa6 430 Gene3D G3DSA:3.40.50.1370 91 394 2.6E-101 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 LH59_07930 7592af6fa87949fffef9756492356aa6 430 PRINTS PR00101 Aspartate carbamoyltransferase signature 313 322 3.9E-29 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 LH59_07930 7592af6fa87949fffef9756492356aa6 430 PRINTS PR00101 Aspartate carbamoyltransferase signature 217 234 3.9E-29 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 LH59_07930 7592af6fa87949fffef9756492356aa6 430 PRINTS PR00101 Aspartate carbamoyltransferase signature 124 146 3.9E-29 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 LH59_07930 7592af6fa87949fffef9756492356aa6 430 PRINTS PR00101 Aspartate carbamoyltransferase signature 163 172 3.9E-29 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 LH59_07930 7592af6fa87949fffef9756492356aa6 430 PRINTS PR00101 Aspartate carbamoyltransferase signature 379 393 3.9E-29 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 LH59_07930 7592af6fa87949fffef9756492356aa6 430 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 90 398 1.0E-89 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 LH59_07930 7592af6fa87949fffef9756492356aa6 430 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 134 153 6.2E-19 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 LH59_07930 7592af6fa87949fffef9756492356aa6 430 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 363 386 6.2E-19 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 LH59_07930 7592af6fa87949fffef9756492356aa6 430 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 218 229 6.2E-19 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 LH59_07930 7592af6fa87949fffef9756492356aa6 430 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 348 357 6.2E-19 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 LH59_07930 7592af6fa87949fffef9756492356aa6 430 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 242 396 3.8E-29 T 14-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 LH59_00880 6a7c1209b480cb5b4a8f645dbdbb7c60 462 PIRSF PIRSF038885 4 345 9.7E-134 T 14-10-2018 IPR030689 Cytochrome b GO:0006122|GO:0008121|GO:0009055|GO:0045275 Reactome: R-HSA-611105 LH59_00880 6a7c1209b480cb5b4a8f645dbdbb7c60 462 PIRSF PIRSF038885 341 462 3.1E-24 T 14-10-2018 IPR030689 Cytochrome b GO:0006122|GO:0008121|GO:0009055|GO:0045275 Reactome: R-HSA-611105 LH59_00880 6a7c1209b480cb5b4a8f645dbdbb7c60 462 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 286 434 1.7E-42 T 14-10-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 LH59_00880 6a7c1209b480cb5b4a8f645dbdbb7c60 462 Pfam PF00033 Cytochrome b/b6/petB 31 219 6.8E-68 T 14-10-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 LH59_00880 6a7c1209b480cb5b4a8f645dbdbb7c60 462 Gene3D G3DSA:1.20.810.10 2 337 1.5E-131 T 14-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 LH59_00880 6a7c1209b480cb5b4a8f645dbdbb7c60 462 SUPERFAMILY SSF81648 290 336 2.4E-9 T 14-10-2018 IPR036150 Cytochrome b/b6, C-terminal domain superfamily GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 LH59_00880 6a7c1209b480cb5b4a8f645dbdbb7c60 462 Gene3D G3DSA:1.20.810.10 338 462 6.7E-25 T 14-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 LH59_00880 6a7c1209b480cb5b4a8f645dbdbb7c60 462 SUPERFAMILY SSF81648 355 447 6.28E-20 T 14-10-2018 IPR036150 Cytochrome b/b6, C-terminal domain superfamily GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 LH59_00880 6a7c1209b480cb5b4a8f645dbdbb7c60 462 SUPERFAMILY SSF81342 15 288 1.88E-96 T 14-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 LH59_09645 b54efe164e8566c46a00208727c93bee 112 PRINTS PR00340 P-II protein signature 52 75 5.8E-42 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 LH59_09645 b54efe164e8566c46a00208727c93bee 112 PRINTS PR00340 P-II protein signature 2 17 5.8E-42 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 LH59_09645 b54efe164e8566c46a00208727c93bee 112 PRINTS PR00340 P-II protein signature 83 103 5.8E-42 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 LH59_09645 b54efe164e8566c46a00208727c93bee 112 PRINTS PR00340 P-II protein signature 23 41 5.8E-42 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 LH59_09645 b54efe164e8566c46a00208727c93bee 112 SUPERFAMILY SSF54913 1 112 1.43E-43 T 14-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta LH59_09645 b54efe164e8566c46a00208727c93bee 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 14-10-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 LH59_09645 b54efe164e8566c46a00208727c93bee 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 2.6E-41 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 LH59_09645 b54efe164e8566c46a00208727c93bee 112 PIRSF PIRSF039144 1 112 1.5E-52 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 LH59_09645 b54efe164e8566c46a00208727c93bee 112 Gene3D G3DSA:3.30.70.120 1 112 1.2E-44 T 14-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal LH59_09645 b54efe164e8566c46a00208727c93bee 112 SMART SM00938 4 105 1.9E-63 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 LH59_20455 7e82e2b928802d7b36ba870828f2cabb 303 Gene3D G3DSA:1.10.10.10 1 81 1.2E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_20455 7e82e2b928802d7b36ba870828f2cabb 303 Gene3D G3DSA:3.40.190.10 163 262 1.2E-27 T 14-10-2018 LH59_20455 7e82e2b928802d7b36ba870828f2cabb 303 SUPERFAMILY SSF46785 1 109 6.46E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_20455 7e82e2b928802d7b36ba870828f2cabb 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.2E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_20455 7e82e2b928802d7b36ba870828f2cabb 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.2E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_20455 7e82e2b928802d7b36ba870828f2cabb 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.2E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_20455 7e82e2b928802d7b36ba870828f2cabb 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 61 3.6E-15 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_20455 7e82e2b928802d7b36ba870828f2cabb 303 Gene3D G3DSA:3.40.190.10 90 268 1.2E-27 T 14-10-2018 LH59_20455 7e82e2b928802d7b36ba870828f2cabb 303 SUPERFAMILY SSF53850 87 290 4.35E-35 T 14-10-2018 LH59_20455 7e82e2b928802d7b36ba870828f2cabb 303 Pfam PF03466 LysR substrate binding domain 88 282 6.4E-34 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_21555 b3667039c2593c5568f08564e2d32edd 467 Gene3D G3DSA:1.20.1250.20 265 466 6.0E-17 T 14-10-2018 LH59_21555 b3667039c2593c5568f08564e2d32edd 467 Pfam PF07690 Major Facilitator Superfamily 29 421 6.3E-45 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_21555 b3667039c2593c5568f08564e2d32edd 467 SUPERFAMILY SSF103473 18 465 1.28E-61 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_21555 b3667039c2593c5568f08564e2d32edd 467 Gene3D G3DSA:1.20.1720.10 26 237 5.6E-48 T 14-10-2018 LH59_21555 b3667039c2593c5568f08564e2d32edd 467 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 26 430 6.2E-70 T 14-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 LH59_17920 91229fc10aa05739f10bf0fc6ea4eb6a 575 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 295 324 2.8E-52 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_17920 91229fc10aa05739f10bf0fc6ea4eb6a 575 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 372 399 2.8E-52 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_17920 91229fc10aa05739f10bf0fc6ea4eb6a 575 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 401 430 2.8E-52 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_17920 91229fc10aa05739f10bf0fc6ea4eb6a 575 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 449 478 2.8E-52 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_17920 91229fc10aa05739f10bf0fc6ea4eb6a 575 Pfam PF00672 HAMP domain 221 267 6.2E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_17920 91229fc10aa05739f10bf0fc6ea4eb6a 575 Pfam PF12729 Four helix bundle sensory module for signal transduction 13 190 1.4E-13 T 14-10-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain LH59_17920 91229fc10aa05739f10bf0fc6ea4eb6a 575 SUPERFAMILY SSF58104 241 522 1.83E-72 T 14-10-2018 LH59_17920 91229fc10aa05739f10bf0fc6ea4eb6a 575 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 334 489 1.1E-51 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 LH59_17920 91229fc10aa05739f10bf0fc6ea4eb6a 575 Gene3D G3DSA:1.10.287.950 221 523 1.0E-89 T 14-10-2018 LH59_17920 91229fc10aa05739f10bf0fc6ea4eb6a 575 SMART SM00283 274 521 4.7E-87 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 LH59_17920 91229fc10aa05739f10bf0fc6ea4eb6a 575 SMART SM00304 221 273 2.5E-9 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_01935 bfc07f02322311abca6094fcdda66df5 384 Gene3D G3DSA:3.40.50.2300 9 338 3.8E-134 T 14-10-2018 LH59_01935 bfc07f02322311abca6094fcdda66df5 384 Pfam PF13433 Periplasmic binding protein domain 7 370 4.1E-144 T 14-10-2018 LH59_01935 bfc07f02322311abca6094fcdda66df5 384 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 7 23 1.4E-7 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 LH59_01935 bfc07f02322311abca6094fcdda66df5 384 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 237 255 1.4E-7 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 LH59_01935 bfc07f02322311abca6094fcdda66df5 384 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 29 45 1.4E-7 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 LH59_01935 bfc07f02322311abca6094fcdda66df5 384 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 48 66 1.4E-7 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 LH59_01935 bfc07f02322311abca6094fcdda66df5 384 SUPERFAMILY SSF53822 6 375 8.75E-91 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_01935 bfc07f02322311abca6094fcdda66df5 384 Gene3D G3DSA:3.40.50.2300 122 357 3.8E-134 T 14-10-2018 LH59_14710 de4ae4fba175135393d625dfd7d8c327 934 Gene3D G3DSA:2.40.128.130 593 934 7.3E-70 T 14-10-2018 IPR036709 Autotransporter beta-domain superfamily LH59_14710 de4ae4fba175135393d625dfd7d8c327 934 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 409 932 1.2E-45 T 14-10-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 LH59_14710 de4ae4fba175135393d625dfd7d8c327 934 SUPERFAMILY SSF51126 144 487 4.08E-19 T 14-10-2018 IPR011050 Pectin lyase fold/virulence factor LH59_14710 de4ae4fba175135393d625dfd7d8c327 934 SMART SM00869 657 924 1.6E-47 T 14-10-2018 IPR005546 Autotransporter beta-domain LH59_14710 de4ae4fba175135393d625dfd7d8c327 934 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 339 370 7.3E-6 T 14-10-2018 IPR013425 Autotransporter-associated beta strand repeat LH59_14710 de4ae4fba175135393d625dfd7d8c327 934 SUPERFAMILY SSF103515 602 934 1.83E-61 T 14-10-2018 IPR036709 Autotransporter beta-domain superfamily LH59_14710 de4ae4fba175135393d625dfd7d8c327 934 Pfam PF03797 Autotransporter beta-domain 660 914 6.2E-60 T 14-10-2018 IPR005546 Autotransporter beta-domain LH59_21040 942c3384c7f2ec4bc6d26f558359d667 500 Gene3D G3DSA:3.40.309.10 257 451 2.2E-140 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 LH59_21040 942c3384c7f2ec4bc6d26f558359d667 500 Gene3D G3DSA:3.40.605.10 24 476 2.2E-140 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 LH59_21040 942c3384c7f2ec4bc6d26f558359d667 500 Pfam PF00171 Aldehyde dehydrogenase family 23 479 1.1E-129 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 LH59_21040 942c3384c7f2ec4bc6d26f558359d667 500 SUPERFAMILY SSF53720 18 487 4.19E-133 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 LH59_21040 942c3384c7f2ec4bc6d26f558359d667 500 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 253 260 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 LH59_07760 12e04f29939978f45c727e3ba0093bf1 376 Gene3D G3DSA:3.30.9.10 83 333 1.0E-32 T 14-10-2018 LH59_07760 12e04f29939978f45c727e3ba0093bf1 376 Gene3D G3DSA:3.50.50.60 5 368 1.0E-32 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_07760 12e04f29939978f45c727e3ba0093bf1 376 SUPERFAMILY SSF51905 3 375 3.95E-30 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_07760 12e04f29939978f45c727e3ba0093bf1 376 TIGRFAM TIGR03364 HpnW_proposed: FAD dependent oxidoreductase TIGR03364 5 368 1.3E-136 T 14-10-2018 IPR017741 FAD-dependent oxidoreductase, HpnW LH59_07760 12e04f29939978f45c727e3ba0093bf1 376 Pfam PF01266 FAD dependent oxidoreductase 5 370 4.0E-34 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 LH59_14090 676d49b54de91b00dccab1049cc49b9e 249 Pfam PF11575 FhuF 2Fe-2S C-terminal domain 211 231 1.8E-4 T 14-10-2018 IPR024726 Ferric iron reductase, C-terminal GO:0051537 LH59_14090 676d49b54de91b00dccab1049cc49b9e 249 TIGRFAM TIGR03950 sidero_Fe_reduc: siderophore ferric iron reductase, AHA_1954 family 9 231 1.4E-59 T 14-10-2018 IPR023998 Siderophore ferric iron reductase, AHA1954 family LH59_18860 6d7394b527aed1dd53fcb4f9c0ed9e01 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 3.6E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_18860 6d7394b527aed1dd53fcb4f9c0ed9e01 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 3.6E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_18860 6d7394b527aed1dd53fcb4f9c0ed9e01 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 3.6E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_18860 6d7394b527aed1dd53fcb4f9c0ed9e01 212 SMART SM00448 3 116 3.5E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_18860 6d7394b527aed1dd53fcb4f9c0ed9e01 212 SMART SM00421 147 204 4.9E-21 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_18860 6d7394b527aed1dd53fcb4f9c0ed9e01 212 Gene3D G3DSA:3.40.50.12740 3 209 2.4E-54 T 14-10-2018 LH59_18860 6d7394b527aed1dd53fcb4f9c0ed9e01 212 Pfam PF00072 Response regulator receiver domain 6 116 4.4E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_18860 6d7394b527aed1dd53fcb4f9c0ed9e01 212 SUPERFAMILY SSF46894 135 209 2.14E-19 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LH59_18860 6d7394b527aed1dd53fcb4f9c0ed9e01 212 ProSitePatterns PS00622 LuxR-type HTH domain signature. 164 191 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_18860 6d7394b527aed1dd53fcb4f9c0ed9e01 212 SUPERFAMILY SSF52172 1 133 5.83E-31 T 14-10-2018 IPR011006 CheY-like superfamily LH59_18860 6d7394b527aed1dd53fcb4f9c0ed9e01 212 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 204 7.6E-18 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_21570 4d8ff88731c896f1722c9b3cca4952d5 90 Pfam PF14542 GCN5-related N-acetyl-transferase 12 88 3.4E-26 T 14-10-2018 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase LH59_21570 4d8ff88731c896f1722c9b3cca4952d5 90 Gene3D G3DSA:3.40.630.30 1 90 1.7E-26 T 14-10-2018 LH59_21570 4d8ff88731c896f1722c9b3cca4952d5 90 SUPERFAMILY SSF55729 1 89 1.68E-27 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_06895 5291f78e589e37215071ba0605610917 127 PIRSF PIRSF000169 8 127 4.8E-39 T 14-10-2018 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 LH59_06895 5291f78e589e37215071ba0605610917 127 TIGRFAM TIGR02968 succ_dehyd_anc: succinate dehydrogenase, hydrophobic membrane anchor protein 16 125 5.7E-34 T 14-10-2018 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 LH59_06895 5291f78e589e37215071ba0605610917 127 Gene3D G3DSA:1.20.1300.10 10 127 1.8E-27 T 14-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 LH59_06895 5291f78e589e37215071ba0605610917 127 SUPERFAMILY SSF81343 11 127 2.78E-24 T 14-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 LH59_06895 5291f78e589e37215071ba0605610917 127 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 4 113 1.7E-14 T 14-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 LH59_08140 683b960b32b1755c00a411e3c92eac74 901 Gene3D G3DSA:2.60.40.1840 464 572 2.5E-29 T 14-10-2018 IPR038438 Alanyl aminopeptidase, Ig-like domain superfamily LH59_08140 683b960b32b1755c00a411e3c92eac74 901 SUPERFAMILY SSF55486 208 470 5.57E-72 T 14-10-2018 LH59_08140 683b960b32b1755c00a411e3c92eac74 901 Pfam PF17432 Domain of unknown function (DUF3458_C) ARM repeats 575 898 1.4E-115 T 14-10-2018 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal LH59_08140 683b960b32b1755c00a411e3c92eac74 901 TIGRFAM TIGR02414 pepN_proteo: aminopeptidase N 13 897 0.0 T 14-10-2018 IPR012779 Peptidase M1, alanyl aminopeptidase GO:0008270 LH59_08140 683b960b32b1755c00a411e3c92eac74 901 Pfam PF11940 Domain of unknown function (DUF3458) Ig-like fold 464 572 1.7E-24 T 14-10-2018 IPR035414 Peptidase M1, alanyl aminopeptidase, Ig-like fold LH59_08140 683b960b32b1755c00a411e3c92eac74 901 Gene3D G3DSA:1.10.1740.60 200 283 3.9E-35 T 14-10-2018 LH59_08140 683b960b32b1755c00a411e3c92eac74 901 Gene3D G3DSA:2.60.40.1730 16 198 3.5E-66 T 14-10-2018 LH59_08140 683b960b32b1755c00a411e3c92eac74 901 Pfam PF01433 Peptidase family M1 domain 212 444 8.9E-55 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LH59_08140 683b960b32b1755c00a411e3c92eac74 901 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 180 195 6.3E-7 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LH59_08140 683b960b32b1755c00a411e3c92eac74 901 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 298 313 6.3E-7 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LH59_08140 683b960b32b1755c00a411e3c92eac74 901 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 262 272 6.3E-7 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LH59_08140 683b960b32b1755c00a411e3c92eac74 901 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 317 329 6.3E-7 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 LH59_08140 683b960b32b1755c00a411e3c92eac74 901 Gene3D G3DSA:1.10.390.10 284 463 2.4E-62 T 14-10-2018 IPR027268 Peptidase M4/M1, CTD superfamily LH59_08140 683b960b32b1755c00a411e3c92eac74 901 SUPERFAMILY SSF63737 9 196 3.27E-39 T 14-10-2018 LH59_08140 683b960b32b1755c00a411e3c92eac74 901 Gene3D G3DSA:1.25.50.10 573 898 2.0E-113 T 14-10-2018 IPR037144 Peptidase M1, alanyl aminopeptidase, C-terminal domain superfamily LH59_14210 f3cdcff8cc9fc7e134ec7c9b2a331d0c 388 Gene3D G3DSA:3.10.580.10 237 386 4.1E-26 T 14-10-2018 LH59_14210 f3cdcff8cc9fc7e134ec7c9b2a331d0c 388 SUPERFAMILY SSF54631 228 366 1.5E-25 T 14-10-2018 LH59_14210 f3cdcff8cc9fc7e134ec7c9b2a331d0c 388 Pfam PF00571 CBS domain 241 292 1.9E-7 T 14-10-2018 IPR000644 CBS domain LH59_14210 f3cdcff8cc9fc7e134ec7c9b2a331d0c 388 Pfam PF00571 CBS domain 312 366 1.3E-7 T 14-10-2018 IPR000644 CBS domain LH59_14210 f3cdcff8cc9fc7e134ec7c9b2a331d0c 388 SMART SM00116 319 366 0.036 T 14-10-2018 IPR000644 CBS domain LH59_14210 f3cdcff8cc9fc7e134ec7c9b2a331d0c 388 SMART SM00116 247 295 0.14 T 14-10-2018 IPR000644 CBS domain LH59_14210 f3cdcff8cc9fc7e134ec7c9b2a331d0c 388 Pfam PF04982 HPP family 54 173 5.6E-36 T 14-10-2018 IPR007065 HPP LH59_23280 e5fd8fc25071f4023d36dfee4601ec2e 226 SUPERFAMILY SSF161098 13 201 2.22E-43 T 14-10-2018 IPR035906 MetI-like superfamily LH59_23280 e5fd8fc25071f4023d36dfee4601ec2e 226 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 110 2.4E-29 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 LH59_23280 e5fd8fc25071f4023d36dfee4601ec2e 226 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 215 8.0E-18 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_23280 e5fd8fc25071f4023d36dfee4601ec2e 226 Gene3D G3DSA:1.10.3720.10 7 218 2.9E-50 T 14-10-2018 IPR035906 MetI-like superfamily LH59_00425 eb54563dd02f0fb8b8729dccdd9fe6da 142 PIRSF PIRSF004638 1 142 2.5E-22 T 14-10-2018 IPR005265 Uncharacterised protein family UPF0093 LH59_00425 eb54563dd02f0fb8b8729dccdd9fe6da 142 Pfam PF03653 Uncharacterised protein family (UPF0093) 2 142 7.4E-17 T 14-10-2018 IPR005265 Uncharacterised protein family UPF0093 LH59_00785 6498e1a90b695c2b3942edc5bfe90a28 575 SMART SM00382 32 231 8.7E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_00785 6498e1a90b695c2b3942edc5bfe90a28 575 SMART SM00382 340 534 2.3E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_00785 6498e1a90b695c2b3942edc5bfe90a28 575 ProSitePatterns PS00211 ABC transporters family signature. 457 471 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_00785 6498e1a90b695c2b3942edc5bfe90a28 575 SUPERFAMILY SSF52540 3 253 1.55E-66 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_00785 6498e1a90b695c2b3942edc5bfe90a28 575 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 536 568 1.1E-4 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_00785 6498e1a90b695c2b3942edc5bfe90a28 575 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 265 2.7E-7 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_00785 6498e1a90b695c2b3942edc5bfe90a28 575 SUPERFAMILY SSF52540 322 555 1.85E-73 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_00785 6498e1a90b695c2b3942edc5bfe90a28 575 Pfam PF00005 ABC transporter 24 181 8.1E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_00785 6498e1a90b695c2b3942edc5bfe90a28 575 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_00785 6498e1a90b695c2b3942edc5bfe90a28 575 Pfam PF00005 ABC transporter 332 485 3.2E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_00785 6498e1a90b695c2b3942edc5bfe90a28 575 Gene3D G3DSA:3.40.50.300 303 574 3.4E-86 T 14-10-2018 LH59_00785 6498e1a90b695c2b3942edc5bfe90a28 575 Gene3D G3DSA:3.40.50.300 1 285 7.3E-86 T 14-10-2018 LH59_03830 eca022600707f31259bbf7d294206e00 190 Hamap MF_00298 RNA pyrophosphohydrolase [rppH]. 1 156 38.077 T 14-10-2018 IPR022927 RNA pyrophosphohydrolase RppH LH59_03830 eca022600707f31259bbf7d294206e00 190 Gene3D G3DSA:3.90.79.10 1 158 6.6E-45 T 14-10-2018 LH59_03830 eca022600707f31259bbf7d294206e00 190 SUPERFAMILY SSF55811 6 165 2.3E-31 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 LH59_03830 eca022600707f31259bbf7d294206e00 190 PRINTS PR00502 NUDIX hydrolase family signature 33 47 9.2E-6 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 LH59_03830 eca022600707f31259bbf7d294206e00 190 PRINTS PR00502 NUDIX hydrolase family signature 47 62 9.2E-6 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 LH59_03830 eca022600707f31259bbf7d294206e00 190 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 LH59_03830 eca022600707f31259bbf7d294206e00 190 Pfam PF00293 NUDIX domain 7 136 1.4E-23 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 LH59_01595 caaec291758ceeafd7cc1f8fad7674cc 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 324 1.3E-45 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_01595 caaec291758ceeafd7cc1f8fad7674cc 325 SUPERFAMILY SSF161098 95 323 4.74E-19 T 14-10-2018 IPR035906 MetI-like superfamily LH59_01595 caaec291758ceeafd7cc1f8fad7674cc 325 Gene3D G3DSA:1.10.3720.10 90 315 6.9E-24 T 14-10-2018 IPR035906 MetI-like superfamily LH59_20645 7140a620509f89a9905b99d944d2c961 246 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 14 29 6.7E-7 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LH59_20645 7140a620509f89a9905b99d944d2c961 246 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 62 77 6.7E-7 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LH59_20645 7140a620509f89a9905b99d944d2c961 246 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 47 62 6.7E-7 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LH59_20645 7140a620509f89a9905b99d944d2c961 246 Gene3D G3DSA:1.10.10.10 7 97 4.8E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_20645 7140a620509f89a9905b99d944d2c961 246 SMART SM00418 12 91 1.8E-18 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LH59_20645 7140a620509f89a9905b99d944d2c961 246 SUPERFAMILY SSF46785 6 89 9.1E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_20645 7140a620509f89a9905b99d944d2c961 246 Pfam PF12840 Helix-turn-helix domain 13 70 6.8E-11 T 14-10-2018 LH59_17600 7b7a105569d886552aa88d38b713d1fb 398 TIGRFAM TIGR03538 DapC_gpp: succinyldiaminopimelate transaminase 1 394 3.7E-186 T 14-10-2018 IPR019878 Succinyldiaminopimelate transaminase, DapC, beta/gammaproteobacteria GO:0009016|GO:0009089 LH59_17600 7b7a105569d886552aa88d38b713d1fb 398 SUPERFAMILY SSF53383 2 394 2.75E-84 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_17600 7b7a105569d886552aa88d38b713d1fb 398 Gene3D G3DSA:3.40.640.10 44 291 3.1E-110 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_17600 7b7a105569d886552aa88d38b713d1fb 398 Gene3D G3DSA:3.90.1150.10 13 381 3.1E-110 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_17600 7b7a105569d886552aa88d38b713d1fb 398 Pfam PF00155 Aminotransferase class I and II 33 376 7.5E-45 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LH59_23805 2e9b4943c8c3ced072a2818455321542 325 Pfam PF12802 MarR family 39 98 2.0E-12 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_23805 2e9b4943c8c3ced072a2818455321542 325 Gene3D G3DSA:1.10.10.10 5 153 8.9E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_23805 2e9b4943c8c3ced072a2818455321542 325 SUPERFAMILY SSF55729 179 312 4.12E-19 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_23805 2e9b4943c8c3ced072a2818455321542 325 Pfam PF00583 Acetyltransferase (GNAT) family 232 300 3.9E-9 T 14-10-2018 IPR000182 GNAT domain LH59_23805 2e9b4943c8c3ced072a2818455321542 325 SMART SM00347 34 134 1.4E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_23805 2e9b4943c8c3ced072a2818455321542 325 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 90 2.3E-5 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_23805 2e9b4943c8c3ced072a2818455321542 325 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 110 2.3E-5 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_23805 2e9b4943c8c3ced072a2818455321542 325 PRINTS PR00598 Bacterial regulatory protein MarR family signature 58 74 2.3E-5 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_23805 2e9b4943c8c3ced072a2818455321542 325 Gene3D G3DSA:3.40.630.30 178 310 2.8E-17 T 14-10-2018 LH59_23805 2e9b4943c8c3ced072a2818455321542 325 SUPERFAMILY SSF46785 13 150 1.91E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_01835 0e26159fecc876edf4f5bb78aa5eb3df 235 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 192 2.1E-32 T 14-10-2018 LH59_01835 0e26159fecc876edf4f5bb78aa5eb3df 235 SUPERFAMILY SSF56784 4 216 2.76E-55 T 14-10-2018 IPR036412 HAD-like superfamily LH59_01835 0e26159fecc876edf4f5bb78aa5eb3df 235 Hamap MF_00495 Phosphoglycolate phosphatase [gph]. 4 222 36.758 T 14-10-2018 IPR037512 Phosphoglycolate phosphatase, prokaryotic GO:0005975|GO:0008967 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 LH59_01835 0e26159fecc876edf4f5bb78aa5eb3df 235 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 106 186 2.3E-10 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 LH59_01835 0e26159fecc876edf4f5bb78aa5eb3df 235 Gene3D G3DSA:1.10.150.240 19 91 2.6E-56 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 LH59_01835 0e26159fecc876edf4f5bb78aa5eb3df 235 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 8 216 4.1E-61 T 14-10-2018 IPR006346 2-phosphoglycolate phosphatase-like, prokaryotic GO:0016791 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 LH59_01835 0e26159fecc876edf4f5bb78aa5eb3df 235 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 4 15 1.4E-7 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 LH59_01835 0e26159fecc876edf4f5bb78aa5eb3df 235 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 136 152 1.4E-7 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 LH59_01835 0e26159fecc876edf4f5bb78aa5eb3df 235 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 105 118 1.4E-7 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 LH59_01835 0e26159fecc876edf4f5bb78aa5eb3df 235 Gene3D G3DSA:3.40.50.1000 7 213 2.6E-56 T 14-10-2018 IPR023214 HAD superfamily LH59_01835 0e26159fecc876edf4f5bb78aa5eb3df 235 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 80 192 8.9E-13 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 LH59_25005 953e1c4aee154d0fd1e13b7d6385658a 298 Pfam PF03466 LysR substrate binding domain 88 293 8.2E-51 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_25005 953e1c4aee154d0fd1e13b7d6385658a 298 SUPERFAMILY SSF46785 4 87 3.89E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_25005 953e1c4aee154d0fd1e13b7d6385658a 298 Gene3D G3DSA:3.40.190.10 92 291 4.6E-69 T 14-10-2018 LH59_25005 953e1c4aee154d0fd1e13b7d6385658a 298 Gene3D G3DSA:3.40.190.10 164 265 4.6E-69 T 14-10-2018 LH59_25005 953e1c4aee154d0fd1e13b7d6385658a 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 2.3E-19 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_25005 953e1c4aee154d0fd1e13b7d6385658a 298 SUPERFAMILY SSF53850 88 296 3.08E-52 T 14-10-2018 LH59_25005 953e1c4aee154d0fd1e13b7d6385658a 298 Gene3D G3DSA:1.10.10.10 3 89 1.6E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_09055 f8174dca50a829481ecce0adf1eba297 290 SUPERFAMILY SSF141673 7 134 7.85E-39 T 14-10-2018 LH59_09055 f8174dca50a829481ecce0adf1eba297 290 Pfam PF03476 MOSC N-terminal beta barrel domain 2 120 3.2E-32 T 14-10-2018 IPR005303 MOSC, N-terminal beta barrel KEGG: 00790+2.8.1.9|MetaCyc: PWY-5963 LH59_09055 f8174dca50a829481ecce0adf1eba297 290 Pfam PF03473 MOSC domain 159 284 2.0E-27 T 14-10-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 LH59_09055 f8174dca50a829481ecce0adf1eba297 290 SUPERFAMILY SSF50800 1 288 2.82E-17 T 14-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily LH59_21715 14cfbf178949c4bd541d6b8f5a387ce5 113 TIGRFAM TIGR02684 dnstrm_HI1420: probable addiction module antidote protein 19 104 5.1E-17 T 14-10-2018 IPR014057 Uncharacterized protein HI1420 LH59_21715 14cfbf178949c4bd541d6b8f5a387ce5 113 SUPERFAMILY SSF47413 53 104 4.63E-6 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 LH59_21575 58c542c3370e057a655d5ffa3090dea5 131 Pfam PF02810 SEC-C motif 8 23 1.3E-5 T 14-10-2018 IPR004027 SEC-C motif LH59_21575 58c542c3370e057a655d5ffa3090dea5 131 SUPERFAMILY SSF103642 6 24 7.85E-5 T 14-10-2018 LH59_21575 58c542c3370e057a655d5ffa3090dea5 131 SUPERFAMILY SSF54427 32 129 1.38E-32 T 14-10-2018 IPR032710 NTF2-like domain superfamily LH59_21575 58c542c3370e057a655d5ffa3090dea5 131 Hamap MF_00612 UPF0225 protein YchJ [ychJ]. 5 129 28.221 T 14-10-2018 IPR023006 Uncharacterised protein family UPF0225 LH59_21575 58c542c3370e057a655d5ffa3090dea5 131 Gene3D G3DSA:3.10.450.50 7 131 2.9E-38 T 14-10-2018 LH59_25075 065373df2fc910af78282e59ad946fa9 232 Pfam PF02798 Glutathione S-transferase, N-terminal domain 21 98 2.2E-12 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 LH59_25075 065373df2fc910af78282e59ad946fa9 232 Pfam PF00043 Glutathione S-transferase, C-terminal domain 142 222 1.3E-8 T 14-10-2018 IPR004046 Glutathione S-transferase, C-terminal LH59_25075 065373df2fc910af78282e59ad946fa9 232 SUPERFAMILY SSF47616 102 229 8.07E-31 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily LH59_25075 065373df2fc910af78282e59ad946fa9 232 Gene3D G3DSA:3.40.30.10 7 231 1.0E-109 T 14-10-2018 LH59_25075 065373df2fc910af78282e59ad946fa9 232 SUPERFAMILY SSF52833 12 102 1.41E-22 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_25075 065373df2fc910af78282e59ad946fa9 232 Gene3D G3DSA:1.20.1050.10 106 221 1.0E-109 T 14-10-2018 LH59_17120 87a76640fed1e28611f5e47d663bf501 601 ProSitePatterns PS00455 Putative AMP-binding domain signature. 185 196 - T 14-10-2018 IPR020845 AMP-binding, conserved site LH59_17120 87a76640fed1e28611f5e47d663bf501 601 Gene3D G3DSA:3.40.50.12780 1 324 7.9E-56 T 14-10-2018 LH59_17120 87a76640fed1e28611f5e47d663bf501 601 Pfam PF00501 AMP-binding enzyme 7 466 5.9E-91 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 LH59_17120 87a76640fed1e28611f5e47d663bf501 601 Gene3D G3DSA:3.40.50.12780 325 459 1.3E-33 T 14-10-2018 LH59_17120 87a76640fed1e28611f5e47d663bf501 601 SUPERFAMILY SSF56801 2 597 3.01E-117 T 14-10-2018 LH59_01025 4ddb4b1748826fc2bd4dc47dad40b608 325 PIRSF PIRSF017082 1 325 7.7E-80 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_01025 4ddb4b1748826fc2bd4dc47dad40b608 325 Gene3D G3DSA:3.40.190.150 29 315 4.2E-116 T 14-10-2018 LH59_01025 4ddb4b1748826fc2bd4dc47dad40b608 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 321 9.3E-90 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_01025 4ddb4b1748826fc2bd4dc47dad40b608 325 Gene3D G3DSA:3.40.190.10 127 250 4.2E-116 T 14-10-2018 LH59_01025 4ddb4b1748826fc2bd4dc47dad40b608 325 SUPERFAMILY SSF53850 112 286 7.33E-12 T 14-10-2018 LH59_20855 e810296435bda856fc465aa3e3973c1c 298 SUPERFAMILY SSF103481 46 144 1.27E-12 T 14-10-2018 LH59_20855 e810296435bda856fc465aa3e3973c1c 298 Pfam PF00892 EamA-like transporter family 13 140 2.9E-17 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_20855 e810296435bda856fc465aa3e3973c1c 298 Pfam PF00892 EamA-like transporter family 153 281 8.6E-13 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_20855 e810296435bda856fc465aa3e3973c1c 298 SUPERFAMILY SSF103481 187 288 1.57E-10 T 14-10-2018 LH59_18640 03088abed442a02a0c3c677891871e4e 135 SUPERFAMILY SSF160631 11 132 2.62E-13 T 14-10-2018 LH59_18640 03088abed442a02a0c3c677891871e4e 135 Gene3D G3DSA:3.40.1580.10 1 133 1.6E-13 T 14-10-2018 IPR037883 Knr4/Smi1-like domain superfamily LH59_18640 03088abed442a02a0c3c677891871e4e 135 Pfam PF14568 SMI1-KNR4 cell-wall 21 128 2.0E-8 T 14-10-2018 LH59_26735 645c884dc12a40eea9c4e7cd6f078ee6 349 Gene3D G3DSA:1.10.1530.10 13 343 1.6E-94 T 14-10-2018 LH59_26735 645c884dc12a40eea9c4e7cd6f078ee6 349 SUPERFAMILY SSF89733 1 345 3.27E-98 T 14-10-2018 IPR036111 Malate/L-sulfolactate/L-lactate dehydrogenase-like superfamily GO:0016491|GO:0055114 LH59_26735 645c884dc12a40eea9c4e7cd6f078ee6 349 Pfam PF02615 Malate/L-lactate dehydrogenase 3 335 3.3E-99 T 14-10-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0016491|GO:0055114 LH59_26735 645c884dc12a40eea9c4e7cd6f078ee6 349 Gene3D G3DSA:1.20.5.460 278 307 1.6E-94 T 14-10-2018 LH59_26735 645c884dc12a40eea9c4e7cd6f078ee6 349 Gene3D G3DSA:3.30.1370.60 60 277 1.6E-94 T 14-10-2018 LH59_15655 2026467e436933326c58b42ad2bdf0cc 604 SUPERFAMILY SSF56801 3 541 1.83E-120 T 14-10-2018 LH59_15655 2026467e436933326c58b42ad2bdf0cc 604 Pfam PF00501 AMP-binding enzyme 8 443 1.3E-74 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 LH59_15655 2026467e436933326c58b42ad2bdf0cc 604 Gene3D G3DSA:3.30.300.30 439 543 2.7E-25 T 14-10-2018 LH59_15655 2026467e436933326c58b42ad2bdf0cc 604 ProSitePatterns PS00455 Putative AMP-binding domain signature. 187 198 - T 14-10-2018 IPR020845 AMP-binding, conserved site LH59_15655 2026467e436933326c58b42ad2bdf0cc 604 Gene3D G3DSA:3.40.50.12780 3 438 5.2E-88 T 14-10-2018 LH59_15655 2026467e436933326c58b42ad2bdf0cc 604 Pfam PF13193 AMP-binding enzyme C-terminal domain 453 528 7.8E-17 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain LH59_13085 ec84c693042d4db300c0a32942493bfd 200 SUPERFAMILY SSF55729 9 181 4.12E-39 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_13085 ec84c693042d4db300c0a32942493bfd 200 Pfam PF13302 Acetyltransferase (GNAT) domain 18 154 7.7E-19 T 14-10-2018 IPR000182 GNAT domain LH59_13085 ec84c693042d4db300c0a32942493bfd 200 Gene3D G3DSA:3.40.630.30 3 199 3.7E-47 T 14-10-2018 LH59_07115 a00bdd771f11e41a59ca7025ccd70f47 54 Hamap MF_01361 UPF0391 membrane protein YtjA [ytjA]. 1 49 20.401 T 14-10-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 LH59_07115 a00bdd771f11e41a59ca7025ccd70f47 54 PIRSF PIRSF036466 1 54 2.0E-21 T 14-10-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 LH59_07115 a00bdd771f11e41a59ca7025ccd70f47 54 Pfam PF07043 Protein of unknown function (DUF1328) 6 43 3.2E-15 T 14-10-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 LH59_06665 8db8bafd521ac15f79496b1899e65ab5 446 Pfam PF11700 Vacuole effluxer Atg22 like 166 441 5.1E-33 T 14-10-2018 IPR024671 Autophagy-related protein 22-like LH59_06665 8db8bafd521ac15f79496b1899e65ab5 446 Pfam PF11700 Vacuole effluxer Atg22 like 79 161 8.6E-6 T 14-10-2018 IPR024671 Autophagy-related protein 22-like LH59_06665 8db8bafd521ac15f79496b1899e65ab5 446 Gene3D G3DSA:1.20.1250.20 261 437 4.6E-18 T 14-10-2018 LH59_06665 8db8bafd521ac15f79496b1899e65ab5 446 SUPERFAMILY SSF103473 35 433 9.94E-39 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_06665 8db8bafd521ac15f79496b1899e65ab5 446 Gene3D G3DSA:1.20.1250.20 35 260 1.7E-9 T 14-10-2018 LH59_15030 a9645529f6f57d592f05d558c95a42ef 270 Pfam PF03466 LysR substrate binding domain 120 244 4.8E-26 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_15030 a9645529f6f57d592f05d558c95a42ef 270 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 8.6E-23 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_15030 a9645529f6f57d592f05d558c95a42ef 270 SUPERFAMILY SSF53850 89 244 3.26E-23 T 14-10-2018 LH59_15030 a9645529f6f57d592f05d558c95a42ef 270 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 5.3E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_15030 a9645529f6f57d592f05d558c95a42ef 270 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 5.3E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_15030 a9645529f6f57d592f05d558c95a42ef 270 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 5.3E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_15030 a9645529f6f57d592f05d558c95a42ef 270 Gene3D G3DSA:1.10.10.10 1 82 2.6E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_15030 a9645529f6f57d592f05d558c95a42ef 270 SUPERFAMILY SSF46785 1 111 1.77E-25 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_15030 a9645529f6f57d592f05d558c95a42ef 270 Gene3D G3DSA:3.40.190.10 120 215 2.7E-22 T 14-10-2018 LH59_13365 a21607e8fee9cecf2198d90b3165fb4b 481 SUPERFAMILY SSF160246 10 73 5.75E-9 T 14-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily LH59_13365 a21607e8fee9cecf2198d90b3165fb4b 481 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 314 328 - T 14-10-2018 IPR001482 Type II/IV secretion system protein LH59_13365 a21607e8fee9cecf2198d90b3165fb4b 481 Gene3D G3DSA:3.40.50.300 220 481 1.2E-108 T 14-10-2018 LH59_13365 a21607e8fee9cecf2198d90b3165fb4b 481 TIGRFAM TIGR02533 type_II_gspE: type II secretion system protein E 10 478 3.8E-210 T 14-10-2018 IPR013369 Type II secretion system GspE GO:0005524|GO:0008565|GO:0015627|GO:0015628 LH59_13365 a21607e8fee9cecf2198d90b3165fb4b 481 Gene3D G3DSA:3.30.450.90 84 219 2.6E-50 T 14-10-2018 LH59_13365 a21607e8fee9cecf2198d90b3165fb4b 481 SMART SM00382 247 370 2.7E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_13365 a21607e8fee9cecf2198d90b3165fb4b 481 SUPERFAMILY SSF52540 101 478 2.6E-104 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_13365 a21607e8fee9cecf2198d90b3165fb4b 481 Pfam PF00437 Type II/IV secretion system protein 124 386 1.3E-85 T 14-10-2018 IPR001482 Type II/IV secretion system protein LH59_05125 d8f0389c206fb5de6623cc2027757f90 388 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 292 308 2.4E-17 T 14-10-2018 LH59_05125 d8f0389c206fb5de6623cc2027757f90 388 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 147 162 2.4E-17 T 14-10-2018 LH59_05125 d8f0389c206fb5de6623cc2027757f90 388 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 277 292 2.4E-17 T 14-10-2018 LH59_05125 d8f0389c206fb5de6623cc2027757f90 388 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 2.4E-17 T 14-10-2018 LH59_05125 d8f0389c206fb5de6623cc2027757f90 388 SUPERFAMILY SSF51905 5 372 3.32E-54 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_05125 d8f0389c206fb5de6623cc2027757f90 388 Pfam PF01494 FAD binding domain 5 315 3.6E-19 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 LH59_05125 d8f0389c206fb5de6623cc2027757f90 388 Gene3D G3DSA:3.30.9.50 41 267 6.3E-62 T 14-10-2018 LH59_05125 d8f0389c206fb5de6623cc2027757f90 388 Gene3D G3DSA:3.50.50.60 8 336 6.3E-62 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_16425 cf958ab677543395f12a88ecd9c07009 149 ProSitePatterns PS00018 EF-hand calcium-binding domain. 117 129 - T 14-10-2018 IPR018247 EF-Hand 1, calcium-binding site LH59_16425 cf958ab677543395f12a88ecd9c07009 149 Pfam PF13202 EF hand 115 129 2.9E-4 T 14-10-2018 IPR002048 EF-hand domain GO:0005509 LH59_16425 cf958ab677543395f12a88ecd9c07009 149 Gene3D G3DSA:1.10.238.10 82 139 6.1E-9 T 14-10-2018 LH59_16425 cf958ab677543395f12a88ecd9c07009 149 SUPERFAMILY SSF47473 65 137 1.17E-9 T 14-10-2018 IPR011992 EF-hand domain pair LH59_07565 fa53077ce848871fe336fb8a56bb22ff 214 TIGRFAM TIGR01262 maiA: maleylacetoacetate isomerase 2 213 1.8E-92 T 14-10-2018 IPR005955 Glutathione S-transferases, class Zeta GO:0003824|GO:0005737|GO:0009072 Reactome: R-HSA-156590|Reactome: R-HSA-204174|Reactome: R-HSA-71182 LH59_07565 fa53077ce848871fe336fb8a56bb22ff 214 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 80 1.4E-17 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 LH59_07565 fa53077ce848871fe336fb8a56bb22ff 214 SUPERFAMILY SSF47616 82 212 9.88E-33 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily LH59_07565 fa53077ce848871fe336fb8a56bb22ff 214 SUPERFAMILY SSF52833 1 85 3.28E-24 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_07565 fa53077ce848871fe336fb8a56bb22ff 214 Gene3D G3DSA:1.20.1050.10 89 214 1.0E-53 T 14-10-2018 LH59_07565 fa53077ce848871fe336fb8a56bb22ff 214 Gene3D G3DSA:3.40.30.10 1 88 3.2E-27 T 14-10-2018 LH59_07565 fa53077ce848871fe336fb8a56bb22ff 214 Pfam PF13410 Glutathione S-transferase, C-terminal domain 136 176 1.5E-6 T 14-10-2018 LH59_13845 08c650080eecced7817cdb71fddaf517 251 Gene3D G3DSA:3.40.50.300 11 251 1.2E-76 T 14-10-2018 LH59_13845 08c650080eecced7817cdb71fddaf517 251 SMART SM00382 36 223 1.1E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_13845 08c650080eecced7817cdb71fddaf517 251 SUPERFAMILY SSF52540 12 245 4.46E-79 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_13845 08c650080eecced7817cdb71fddaf517 251 PIRSF PIRSF039085 8 251 1.3E-106 T 14-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 LH59_13845 08c650080eecced7817cdb71fddaf517 251 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_13845 08c650080eecced7817cdb71fddaf517 251 Pfam PF00005 ABC transporter 27 175 3.9E-35 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_07745 45a0ae9dda2ca8e579a1f99f6bb9df33 565 SUPERFAMILY SSF161098 20 268 2.62E-44 T 14-10-2018 IPR035906 MetI-like superfamily LH59_07745 45a0ae9dda2ca8e579a1f99f6bb9df33 565 Gene3D G3DSA:1.10.3720.10 292 557 9.6E-29 T 14-10-2018 IPR035906 MetI-like superfamily LH59_07745 45a0ae9dda2ca8e579a1f99f6bb9df33 565 SUPERFAMILY SSF161098 302 544 7.46E-32 T 14-10-2018 IPR035906 MetI-like superfamily LH59_07745 45a0ae9dda2ca8e579a1f99f6bb9df33 565 Gene3D G3DSA:1.10.3720.10 7 275 6.1E-51 T 14-10-2018 IPR035906 MetI-like superfamily LH59_07745 45a0ae9dda2ca8e579a1f99f6bb9df33 565 TIGRFAM TIGR03262 PhnU2: putative 2-aminoethylphosphonate ABC transporter, permease protein 21 561 8.7E-246 T 14-10-2018 IPR017664 2-aminoethylphosphonate ABC transport system, permease protein, putative LH59_07745 45a0ae9dda2ca8e579a1f99f6bb9df33 565 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 384 546 1.4E-7 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_07745 45a0ae9dda2ca8e579a1f99f6bb9df33 565 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 271 3.2E-12 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_21510 d2f021d92f4df3a39955c4d77c520e62 885 Pfam PF08264 Anticodon-binding domain of tRNA 724 847 1.1E-13 T 14-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 LH59_21510 d2f021d92f4df3a39955c4d77c520e62 885 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 228 420 6.0E-66 T 14-10-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 LH59_21510 d2f021d92f4df3a39955c4d77c520e62 885 Gene3D G3DSA:1.10.730.10 9 817 0.0 T 14-10-2018 LH59_21510 d2f021d92f4df3a39955c4d77c520e62 885 Gene3D G3DSA:3.90.740.10 234 432 0.0 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 LH59_21510 d2f021d92f4df3a39955c4d77c520e62 885 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 435 590 2.3E-8 T 14-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 LH59_21510 d2f021d92f4df3a39955c4d77c520e62 885 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 48 59 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 LH59_21510 d2f021d92f4df3a39955c4d77c520e62 885 SUPERFAMILY SSF52374 7 687 2.45E-144 T 14-10-2018 LH59_21510 d2f021d92f4df3a39955c4d77c520e62 885 SUPERFAMILY SSF50677 233 432 8.69E-51 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 LH59_21510 d2f021d92f4df3a39955c4d77c520e62 885 Gene3D G3DSA:3.40.50.620 39 585 0.0 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LH59_21510 d2f021d92f4df3a39955c4d77c520e62 885 SUPERFAMILY SSF47323 682 884 1.59E-28 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 LH59_21510 d2f021d92f4df3a39955c4d77c520e62 885 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 26 884 0.0 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 LH59_21510 d2f021d92f4df3a39955c4d77c520e62 885 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 4 885 22.454 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 LH59_21510 d2f021d92f4df3a39955c4d77c520e62 885 PRINTS PR00985 Leucyl-tRNA synthetase signature 191 204 1.8E-48 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 LH59_21510 d2f021d92f4df3a39955c4d77c520e62 885 PRINTS PR00985 Leucyl-tRNA synthetase signature 576 586 1.8E-48 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 LH59_21510 d2f021d92f4df3a39955c4d77c520e62 885 PRINTS PR00985 Leucyl-tRNA synthetase signature 159 175 1.8E-48 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 LH59_21510 d2f021d92f4df3a39955c4d77c520e62 885 PRINTS PR00985 Leucyl-tRNA synthetase signature 505 523 1.8E-48 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 LH59_21510 d2f021d92f4df3a39955c4d77c520e62 885 PRINTS PR00985 Leucyl-tRNA synthetase signature 543 565 1.8E-48 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 LH59_21510 d2f021d92f4df3a39955c4d77c520e62 885 PRINTS PR00985 Leucyl-tRNA synthetase signature 222 241 1.8E-48 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 LH59_21510 d2f021d92f4df3a39955c4d77c520e62 885 PRINTS PR00985 Leucyl-tRNA synthetase signature 133 150 1.8E-48 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 LH59_21510 d2f021d92f4df3a39955c4d77c520e62 885 Pfam PF09334 tRNA synthetases class I (M) 44 177 1.6E-17 T 14-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 LH59_21510 d2f021d92f4df3a39955c4d77c520e62 885 Gene3D G3DSA:3.10.20.590 827 885 4.9E-20 T 14-10-2018 LH59_21510 d2f021d92f4df3a39955c4d77c520e62 885 Gene3D G3DSA:3.10.330.110 586 648 0.0 T 14-10-2018 LH59_24260 58c7bbbf6410abde00e72f0c10d0cad7 691 SUPERFAMILY SSF89372 271 491 7.59E-12 T 14-10-2018 LH59_24260 58c7bbbf6410abde00e72f0c10d0cad7 691 Gene3D G3DSA:3.40.50.10320 39 274 2.3E-12 T 14-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 LH59_24260 58c7bbbf6410abde00e72f0c10d0cad7 691 Pfam PF02585 GlcNAc-PI de-N-acetylase 41 230 1.5E-16 T 14-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 LH59_24260 58c7bbbf6410abde00e72f0c10d0cad7 691 SUPERFAMILY SSF102588 40 234 5.1E-15 T 14-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 LH59_11545 1d20f8f05579cb5efb512a858399c730 107 Gene3D G3DSA:3.40.1690.10 15 94 1.9E-23 T 14-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal LH59_11545 1d20f8f05579cb5efb512a858399c730 107 Pfam PF01312 FlhB HrpN YscU SpaS Family 16 89 8.4E-17 T 14-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 LH59_11545 1d20f8f05579cb5efb512a858399c730 107 SUPERFAMILY SSF160544 16 93 6.93E-22 T 14-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal LH59_23705 3bedf97b37cfc51f49a49c971ef65b2d 444 Pfam PF00083 Sugar (and other) transporter 41 229 7.2E-15 T 14-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 LH59_23705 3bedf97b37cfc51f49a49c971ef65b2d 444 Gene3D G3DSA:1.20.1250.20 33 444 3.5E-41 T 14-10-2018 LH59_23705 3bedf97b37cfc51f49a49c971ef65b2d 444 SUPERFAMILY SSF103473 36 435 9.42E-39 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_23705 3bedf97b37cfc51f49a49c971ef65b2d 444 ProSitePatterns PS00216 Sugar transport proteins signature 1. 315 332 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 LH59_19260 fe8d58f1e736dc78eab5ebe363ea34a6 448 Gene3D G3DSA:3.40.640.10 87 439 1.4E-58 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_19260 fe8d58f1e736dc78eab5ebe363ea34a6 448 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 81 1.3E-12 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_19260 fe8d58f1e736dc78eab5ebe363ea34a6 448 Gene3D G3DSA:1.10.10.10 14 85 5.0E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_19260 fe8d58f1e736dc78eab5ebe363ea34a6 448 SUPERFAMILY SSF46785 19 85 2.53E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_19260 fe8d58f1e736dc78eab5ebe363ea34a6 448 Pfam PF00155 Aminotransferase class I and II 91 439 1.8E-21 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LH59_19260 fe8d58f1e736dc78eab5ebe363ea34a6 448 SUPERFAMILY SSF53383 77 442 5.7E-65 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_19260 fe8d58f1e736dc78eab5ebe363ea34a6 448 SMART SM00345 22 81 6.5E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_20030 9ef9f63520da46836be25a2e75a9c3b8 248 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 196 4.4E-7 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_20030 9ef9f63520da46836be25a2e75a9c3b8 248 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 180 4.4E-7 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_20030 9ef9f63520da46836be25a2e75a9c3b8 248 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 196 208 4.4E-7 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_20030 9ef9f63520da46836be25a2e75a9c3b8 248 SMART SM00421 163 220 5.8E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_20030 9ef9f63520da46836be25a2e75a9c3b8 248 SUPERFAMILY SSF46894 160 224 3.74E-15 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LH59_20030 9ef9f63520da46836be25a2e75a9c3b8 248 SUPERFAMILY SSF52172 2 128 7.16E-6 T 14-10-2018 IPR011006 CheY-like superfamily LH59_20030 9ef9f63520da46836be25a2e75a9c3b8 248 Pfam PF00196 Bacterial regulatory proteins, luxR family 166 217 2.6E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_20030 9ef9f63520da46836be25a2e75a9c3b8 248 Gene3D G3DSA:3.40.50.12740 3 225 5.8E-21 T 14-10-2018 LH59_07540 22730ea0425c7141bdfc78e48b197cbd 282 TIGRFAM TIGR03036 trp_2_3_diox: tryptophan 2,3-dioxygenase 19 282 3.2E-132 T 14-10-2018 IPR017485 Tryptophan 2,3-dioxygenase, bacterial GO:0004833|GO:0019441 KEGG: 00380+1.13.11.11 LH59_07540 22730ea0425c7141bdfc78e48b197cbd 282 Pfam PF03301 Tryptophan 2,3-dioxygenase 14 208 3.5E-41 T 14-10-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 LH59_07540 22730ea0425c7141bdfc78e48b197cbd 282 Hamap MF_01972 Tryptophan 2,3-dioxygenase [kynA]. 19 282 41.076 T 14-10-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 LH59_07540 22730ea0425c7141bdfc78e48b197cbd 282 Gene3D G3DSA:1.20.58.480 23 282 7.0E-98 T 14-10-2018 LH59_07540 22730ea0425c7141bdfc78e48b197cbd 282 SUPERFAMILY SSF140959 25 281 8.11E-103 T 14-10-2018 IPR037217 Tryptophan/Indoleamine 2,3-dioxygenase-like GO:0019441|GO:0020037|GO:0046872 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 LH59_22160 497f9f1f51f91c8ed2ca1b5a0c2a5c9b 129 Pfam PF13467 Ribbon-helix-helix domain 16 82 4.8E-26 T 14-10-2018 IPR027373 Ribbon-helix-helix domain LH59_22160 497f9f1f51f91c8ed2ca1b5a0c2a5c9b 129 Gene3D G3DSA:1.10.3990.20 8 116 7.8E-47 T 14-10-2018 IPR038268 Ribbon-helix-helix domain superfamily LH59_18950 5e8f199902a9889d625edc0fdfa6ac14 180 Pfam PF08281 Sigma-70, region 4 108 160 8.3E-15 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LH59_18950 5e8f199902a9889d625edc0fdfa6ac14 180 Pfam PF04542 Sigma-70 region 2 22 77 1.9E-5 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 LH59_18950 5e8f199902a9889d625edc0fdfa6ac14 180 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 6 162 3.5E-20 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 LH59_18950 5e8f199902a9889d625edc0fdfa6ac14 180 SUPERFAMILY SSF88659 91 171 7.63E-13 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like LH59_18950 5e8f199902a9889d625edc0fdfa6ac14 180 Gene3D G3DSA:1.10.10.10 79 171 2.2E-13 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_18950 5e8f199902a9889d625edc0fdfa6ac14 180 SUPERFAMILY SSF88946 6 92 7.46E-9 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 LH59_03990 e273932cfdddc66696727744dbb0f1ee 397 Pfam PF01546 Peptidase family M20/M25/M40 78 390 7.8E-35 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 LH59_03990 e273932cfdddc66696727744dbb0f1ee 397 SUPERFAMILY SSF53187 8 391 3.4E-86 T 14-10-2018 LH59_03990 e273932cfdddc66696727744dbb0f1ee 397 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 17 381 5.9E-113 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 LH59_03990 e273932cfdddc66696727744dbb0f1ee 397 Gene3D G3DSA:3.30.70.360 186 302 4.0E-135 T 14-10-2018 LH59_03990 e273932cfdddc66696727744dbb0f1ee 397 PIRSF PIRSF005962 2 395 6.1E-126 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 LH59_03990 e273932cfdddc66696727744dbb0f1ee 397 Pfam PF07687 Peptidase dimerisation domain 191 287 5.3E-8 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain LH59_03990 e273932cfdddc66696727744dbb0f1ee 397 Gene3D G3DSA:3.40.630.10 18 377 4.0E-135 T 14-10-2018 LH59_03990 e273932cfdddc66696727744dbb0f1ee 397 SUPERFAMILY SSF55031 188 303 3.93E-28 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain LH59_11535 db2b888b8d7cce8c80c6107310e6cc68 110 Pfam PF02049 Flagellar hook-basal body complex protein FliE 25 110 6.9E-27 T 14-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 LH59_11535 db2b888b8d7cce8c80c6107310e6cc68 110 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 95 108 2.1E-13 T 14-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 LH59_11535 db2b888b8d7cce8c80c6107310e6cc68 110 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 39 55 2.1E-13 T 14-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 LH59_11535 db2b888b8d7cce8c80c6107310e6cc68 110 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 74 90 2.1E-13 T 14-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 LH59_11535 db2b888b8d7cce8c80c6107310e6cc68 110 TIGRFAM TIGR00205 fliE: flagellar hook-basal body complex protein FliE 14 109 5.1E-21 T 14-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 LH59_11535 db2b888b8d7cce8c80c6107310e6cc68 110 Hamap MF_00724 Flagellar hook-basal body complex protein FliE [fliE]. 4 110 16.975 T 14-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 LH59_02105 10277f4eac621efa481a7b61c854411f 327 Gene3D G3DSA:3.40.50.300 3 326 9.4E-100 T 14-10-2018 LH59_02105 10277f4eac621efa481a7b61c854411f 327 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 299 5.1E-19 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_02105 10277f4eac621efa481a7b61c854411f 327 SUPERFAMILY SSF52540 34 307 1.45E-68 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_02105 10277f4eac621efa481a7b61c854411f 327 Pfam PF00005 ABC transporter 26 183 4.0E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_02105 10277f4eac621efa481a7b61c854411f 327 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 317 1.5E-23 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_02105 10277f4eac621efa481a7b61c854411f 327 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_02105 10277f4eac621efa481a7b61c854411f 327 SMART SM00382 34 233 9.6E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_12985 c3b986a64282bb25d43ea58cbe456932 204 Gene3D G3DSA:3.40.30.10 2 200 2.6E-70 T 14-10-2018 LH59_12985 c3b986a64282bb25d43ea58cbe456932 204 SUPERFAMILY SSF47616 77 202 5.46E-24 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily LH59_12985 c3b986a64282bb25d43ea58cbe456932 204 SUPERFAMILY SSF52833 1 80 1.42E-20 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_12985 c3b986a64282bb25d43ea58cbe456932 204 Pfam PF00043 Glutathione S-transferase, C-terminal domain 115 188 2.1E-8 T 14-10-2018 IPR004046 Glutathione S-transferase, C-terminal LH59_12985 c3b986a64282bb25d43ea58cbe456932 204 Gene3D G3DSA:1.20.1050.10 79 191 2.6E-70 T 14-10-2018 LH59_12985 c3b986a64282bb25d43ea58cbe456932 204 Pfam PF02798 Glutathione S-transferase, N-terminal domain 1 71 3.2E-12 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 LH59_22705 84621687fc4db82a14e89b0f8b92fed6 384 SUPERFAMILY SSF53822 26 382 1.53E-70 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_22705 84621687fc4db82a14e89b0f8b92fed6 384 Gene3D G3DSA:3.40.50.2300 143 375 2.2E-109 T 14-10-2018 LH59_22705 84621687fc4db82a14e89b0f8b92fed6 384 Gene3D G3DSA:3.40.50.2300 28 366 2.2E-109 T 14-10-2018 LH59_22705 84621687fc4db82a14e89b0f8b92fed6 384 Pfam PF13458 Periplasmic binding protein 25 379 1.4E-49 T 14-10-2018 IPR028081 Leucine-binding protein domain LH59_16900 d4dba28d2d926c3ff0df030be11758d1 340 Gene3D G3DSA:3.40.50.1000 125 326 3.8E-45 T 14-10-2018 IPR023214 HAD superfamily LH59_16900 d4dba28d2d926c3ff0df030be11758d1 340 Pfam PF12710 haloacid dehalogenase-like hydrolase 73 277 4.9E-25 T 14-10-2018 LH59_16900 d4dba28d2d926c3ff0df030be11758d1 340 SUPERFAMILY SSF56784 71 325 2.62E-25 T 14-10-2018 IPR036412 HAD-like superfamily LH59_25065 787dab6186ecd1e164def23d686939f0 299 SUPERFAMILY SSF46626 181 283 3.58E-19 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_25065 787dab6186ecd1e164def23d686939f0 299 Gene3D G3DSA:1.10.760.10 174 296 2.7E-40 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_25065 787dab6186ecd1e164def23d686939f0 299 SUPERFAMILY SSF46626 51 166 2.15E-23 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_25065 787dab6186ecd1e164def23d686939f0 299 Pfam PF00034 Cytochrome c 185 274 1.9E-9 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_25065 787dab6186ecd1e164def23d686939f0 299 Gene3D G3DSA:1.10.760.10 43 171 1.3E-36 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_06125 cab826ac05077814ee79c4cac433967c 164 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 10 158 1.5E-57 T 14-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06125 cab826ac05077814ee79c4cac433967c 164 Gene3D G3DSA:3.40.30.10 75 164 1.9E-22 T 14-10-2018 LH59_06125 cab826ac05077814ee79c4cac433967c 164 PIRSF PIRSF000216 2 164 3.7E-54 T 14-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06125 cab826ac05077814ee79c4cac433967c 164 SUPERFAMILY SSF52833 3 159 1.23E-48 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_06125 cab826ac05077814ee79c4cac433967c 164 Gene3D G3DSA:1.10.10.1590 1 74 1.5E-22 T 14-10-2018 LH59_06125 cab826ac05077814ee79c4cac433967c 164 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 12 158 4.6E-46 T 14-10-2018 LH59_11480 fb224d2a3e180829e70bdcb48110fd77 247 Pfam PF00813 FliP family 49 241 4.5E-78 T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 LH59_11480 fb224d2a3e180829e70bdcb48110fd77 247 TIGRFAM TIGR01103 fliP: flagellar biosynthetic protein FliP 49 245 1.7E-90 T 14-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 LH59_11480 fb224d2a3e180829e70bdcb48110fd77 247 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 222 234 - T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 LH59_11480 fb224d2a3e180829e70bdcb48110fd77 247 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 86 105 1.9E-63 T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 LH59_11480 fb224d2a3e180829e70bdcb48110fd77 247 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 47 66 1.9E-63 T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 LH59_11480 fb224d2a3e180829e70bdcb48110fd77 247 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 66 86 1.9E-63 T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 LH59_11480 fb224d2a3e180829e70bdcb48110fd77 247 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 219 244 1.9E-63 T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 LH59_11480 fb224d2a3e180829e70bdcb48110fd77 247 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 174 194 1.9E-63 T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 LH59_11480 fb224d2a3e180829e70bdcb48110fd77 247 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 195 216 1.9E-63 T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 LH59_11480 fb224d2a3e180829e70bdcb48110fd77 247 ProSitePatterns PS01060 Flagella transport protein fliP family signature 1. 174 189 - T 14-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 LH59_11480 fb224d2a3e180829e70bdcb48110fd77 247 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 235 245 5.8E-32 T 14-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 LH59_11480 fb224d2a3e180829e70bdcb48110fd77 247 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 105 117 5.8E-32 T 14-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 LH59_11480 fb224d2a3e180829e70bdcb48110fd77 247 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 117 131 5.8E-32 T 14-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 LH59_11480 fb224d2a3e180829e70bdcb48110fd77 247 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 145 157 5.8E-32 T 14-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 LH59_11480 fb224d2a3e180829e70bdcb48110fd77 247 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 167 179 5.8E-32 T 14-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 LH59_11480 fb224d2a3e180829e70bdcb48110fd77 247 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 45 54 5.8E-32 T 14-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 LH59_27985 83f1df1823ecf0154ac31369de14c554 174 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 160 26.394 T 14-10-2018 IPR022973 Ribosomal protein L10 LH59_27985 83f1df1823ecf0154ac31369de14c554 174 ProSitePatterns PS01109 Ribosomal protein L10 signature. 8 42 - T 14-10-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_27985 83f1df1823ecf0154ac31369de14c554 174 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 71 143 9.0E-4 T 14-10-2018 LH59_27985 83f1df1823ecf0154ac31369de14c554 174 Gene3D G3DSA:3.30.70.1730 3 133 2.7E-33 T 14-10-2018 LH59_27985 83f1df1823ecf0154ac31369de14c554 174 Pfam PF00466 Ribosomal protein L10 4 100 1.4E-21 T 14-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 LH59_27985 83f1df1823ecf0154ac31369de14c554 174 SUPERFAMILY SSF160369 3 171 9.15E-53 T 14-10-2018 LH59_03405 d26c8c8739cf93f73a822fdbeca37516 218 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 80 201 4.0E-19 T 14-10-2018 IPR005247 YbhB/YbcL LH59_03405 d26c8c8739cf93f73a822fdbeca37516 218 SUPERFAMILY SSF49777 1 204 2.22E-43 T 14-10-2018 IPR036610 PEBP-like superfamily LH59_03405 d26c8c8739cf93f73a822fdbeca37516 218 Pfam PF01161 Phosphatidylethanolamine-binding protein 31 201 3.5E-40 T 14-10-2018 IPR008914 Phosphatidylethanolamine-binding protein LH59_03405 d26c8c8739cf93f73a822fdbeca37516 218 Gene3D G3DSA:3.90.280.10 1 202 3.8E-50 T 14-10-2018 IPR036610 PEBP-like superfamily LH59_07640 35f8d762bfc1caad940bb5534416c120 133 Pfam PF02033 Ribosome-binding factor A 12 112 1.1E-23 T 14-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 LH59_07640 35f8d762bfc1caad940bb5534416c120 133 Gene3D G3DSA:3.30.300.20 9 107 1.1E-24 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta LH59_07640 35f8d762bfc1caad940bb5534416c120 133 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 12 115 5.1E-20 T 14-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 LH59_07640 35f8d762bfc1caad940bb5534416c120 133 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 15 100 3.0E-41 T 14-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 LH59_07640 35f8d762bfc1caad940bb5534416c120 133 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 11 113 21.143 T 14-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 LH59_07640 35f8d762bfc1caad940bb5534416c120 133 SUPERFAMILY SSF89919 12 116 3.53E-25 T 14-10-2018 IPR023799 Ribosome-binding factor A domain superfamily LH59_04090 b861379226a4e28bf28690eaa956e5d8 911 Gene3D G3DSA:3.90.1440.10 228 368 6.8E-174 T 14-10-2018 LH59_04090 b861379226a4e28bf28690eaa956e5d8 911 Pfam PF02810 SEC-C motif 891 909 1.8E-10 T 14-10-2018 IPR004027 SEC-C motif LH59_04090 b861379226a4e28bf28690eaa956e5d8 911 SMART SM00958 227 358 1.1E-72 T 14-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 LH59_04090 b861379226a4e28bf28690eaa956e5d8 911 SUPERFAMILY SSF52540 4 415 3.76E-84 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_04090 b861379226a4e28bf28690eaa956e5d8 911 Gene3D G3DSA:3.40.50.300 417 626 3.2E-89 T 14-10-2018 LH59_04090 b861379226a4e28bf28690eaa956e5d8 911 SUPERFAMILY SSF52540 416 625 2.59E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_04090 b861379226a4e28bf28690eaa956e5d8 911 PRINTS PR00906 SecA protein signature 100 114 3.4E-73 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 LH59_04090 b861379226a4e28bf28690eaa956e5d8 911 PRINTS PR00906 SecA protein signature 116 126 3.4E-73 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 LH59_04090 b861379226a4e28bf28690eaa956e5d8 911 PRINTS PR00906 SecA protein signature 413 426 3.4E-73 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 LH59_04090 b861379226a4e28bf28690eaa956e5d8 911 PRINTS PR00906 SecA protein signature 169 189 3.4E-73 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 LH59_04090 b861379226a4e28bf28690eaa956e5d8 911 PRINTS PR00906 SecA protein signature 339 361 3.4E-73 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 LH59_04090 b861379226a4e28bf28690eaa956e5d8 911 PRINTS PR00906 SecA protein signature 62 86 3.4E-73 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 LH59_04090 b861379226a4e28bf28690eaa956e5d8 911 PRINTS PR00906 SecA protein signature 376 393 3.4E-73 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 LH59_04090 b861379226a4e28bf28690eaa956e5d8 911 SUPERFAMILY SSF81886 628 899 7.19E-81 T 14-10-2018 IPR036266 SecA, Wing/Scaffold superfamily LH59_04090 b861379226a4e28bf28690eaa956e5d8 911 ProSitePatterns PS01312 SecA family signature. 500 515 - T 14-10-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 LH59_04090 b861379226a4e28bf28690eaa956e5d8 911 SUPERFAMILY SSF81767 226 368 3.79E-41 T 14-10-2018 IPR036670 SecA, preprotein cross-linking domain superfamily GO:0016020|GO:0017038 LH59_04090 b861379226a4e28bf28690eaa956e5d8 911 Pfam PF07517 SecA DEAD-like domain 5 402 2.9E-130 T 14-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 LH59_04090 b861379226a4e28bf28690eaa956e5d8 911 Hamap MF_01382 Protein translocase subunit SecA [secA]. 4 839 20.022 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 LH59_04090 b861379226a4e28bf28690eaa956e5d8 911 Pfam PF01043 SecA preprotein cross-linking domain 232 358 1.8E-34 T 14-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 LH59_04090 b861379226a4e28bf28690eaa956e5d8 911 SMART SM00957 5 402 1.0E-300 T 14-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 LH59_04090 b861379226a4e28bf28690eaa956e5d8 911 Gene3D G3DSA:3.40.50.300 21 415 6.8E-174 T 14-10-2018 LH59_04090 b861379226a4e28bf28690eaa956e5d8 911 Gene3D G3DSA:1.10.3060.10 628 840 3.2E-76 T 14-10-2018 LH59_04090 b861379226a4e28bf28690eaa956e5d8 911 Pfam PF07516 SecA Wing and Scaffold domain 624 836 2.0E-66 T 14-10-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 LH59_04090 b861379226a4e28bf28690eaa956e5d8 911 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 27 825 0.0 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 LH59_23810 60fdf2666298819968022a201e6eea7f 270 Pfam PF00149 Calcineurin-like phosphoesterase 20 233 1.4E-8 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 LH59_23810 60fdf2666298819968022a201e6eea7f 270 Gene3D G3DSA:3.60.21.10 1 258 3.0E-12 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like LH59_23810 60fdf2666298819968022a201e6eea7f 270 SUPERFAMILY SSF56300 1 258 7.89E-26 T 14-10-2018 LH59_08975 3f711eabb0a101628208827174d3e6e1 921 SUPERFAMILY SSF81593 792 920 1.02E-32 T 14-10-2018 LH59_08975 3f711eabb0a101628208827174d3e6e1 921 Gene3D G3DSA:1.20.120.1510 442 551 1.8E-15 T 14-10-2018 LH59_08975 3f711eabb0a101628208827174d3e6e1 921 Gene3D G3DSA:1.20.120.330 789 921 1.0E-40 T 14-10-2018 LH59_08975 3f711eabb0a101628208827174d3e6e1 921 Gene3D G3DSA:1.20.120.330 270 429 8.6E-50 T 14-10-2018 LH59_08975 3f711eabb0a101628208827174d3e6e1 921 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 543 782 2.0E-63 T 14-10-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 LH59_08975 3f711eabb0a101628208827174d3e6e1 921 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 8 244 2.1E-57 T 14-10-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 LH59_08975 3f711eabb0a101628208827174d3e6e1 921 SUPERFAMILY SSF81301 517 792 2.26E-73 T 14-10-2018 LH59_08975 3f711eabb0a101628208827174d3e6e1 921 Hamap MF_00802 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme [glnE]. 2 921 18.391 T 14-10-2018 IPR023057 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme GO:0008882 LH59_08975 3f711eabb0a101628208827174d3e6e1 921 SUPERFAMILY SSF81301 6 271 9.81E-65 T 14-10-2018 LH59_08975 3f711eabb0a101628208827174d3e6e1 921 Pfam PF08335 GlnD PII-uridylyltransferase 804 897 4.9E-10 T 14-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 LH59_08975 3f711eabb0a101628208827174d3e6e1 921 Pfam PF08335 GlnD PII-uridylyltransferase 282 427 2.4E-40 T 14-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 LH59_08975 3f711eabb0a101628208827174d3e6e1 921 Gene3D G3DSA:3.30.460.100 552 788 9.3E-74 T 14-10-2018 LH59_08975 3f711eabb0a101628208827174d3e6e1 921 Gene3D G3DSA:3.30.460.100 14 257 5.0E-62 T 14-10-2018 LH59_08975 3f711eabb0a101628208827174d3e6e1 921 SUPERFAMILY SSF81593 272 427 2.35E-37 T 14-10-2018 LH59_20005 303aa7785e8ac828af85838a9e351e9a 376 Gene3D G3DSA:3.40.50.2000 197 352 1.2E-33 T 14-10-2018 LH59_20005 303aa7785e8ac828af85838a9e351e9a 376 Gene3D G3DSA:3.40.50.2000 4 196 1.1E-21 T 14-10-2018 LH59_20005 303aa7785e8ac828af85838a9e351e9a 376 Pfam PF13439 Glycosyltransferase Family 4 13 179 2.7E-20 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 LH59_20005 303aa7785e8ac828af85838a9e351e9a 376 SUPERFAMILY SSF53756 4 368 3.85E-67 T 14-10-2018 LH59_20005 303aa7785e8ac828af85838a9e351e9a 376 Pfam PF00534 Glycosyl transferases group 1 194 348 1.4E-27 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 LH59_09025 ecbe9d10eea0c187b4dbd0409c2658f3 315 Gene3D G3DSA:3.40.50.10490 105 297 2.3E-25 T 14-10-2018 LH59_09025 ecbe9d10eea0c187b4dbd0409c2658f3 315 Gene3D G3DSA:1.10.10.10 3 82 1.5E-10 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_09025 ecbe9d10eea0c187b4dbd0409c2658f3 315 Pfam PF01380 SIS domain 134 242 1.3E-11 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 LH59_09025 ecbe9d10eea0c187b4dbd0409c2658f3 315 SUPERFAMILY SSF46689 3 77 1.34E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_09025 ecbe9d10eea0c187b4dbd0409c2658f3 315 SUPERFAMILY SSF53697 109 269 3.34E-15 T 14-10-2018 LH59_23890 a70d75c71817dd4d4a3d47163a2e7189 403 Pfam PF01494 FAD binding domain 269 387 1.3E-12 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 LH59_23890 a70d75c71817dd4d4a3d47163a2e7189 403 Gene3D G3DSA:3.50.50.60 3 396 3.2E-81 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_23890 a70d75c71817dd4d4a3d47163a2e7189 403 Pfam PF13450 NAD(P)-binding Rossmann-like domain 8 38 3.5E-5 T 14-10-2018 LH59_23890 a70d75c71817dd4d4a3d47163a2e7189 403 SUPERFAMILY SSF51905 1 396 2.71E-35 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_23890 a70d75c71817dd4d4a3d47163a2e7189 403 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 321 336 3.4E-15 T 14-10-2018 LH59_23890 a70d75c71817dd4d4a3d47163a2e7189 403 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 3.4E-15 T 14-10-2018 LH59_23890 a70d75c71817dd4d4a3d47163a2e7189 403 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 336 352 3.4E-15 T 14-10-2018 LH59_18210 833f8486a377824bb1ee184edb45645a 433 Pfam PF00083 Sugar (and other) transporter 19 222 3.6E-27 T 14-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 LH59_18210 833f8486a377824bb1ee184edb45645a 433 Gene3D G3DSA:1.20.1250.20 13 433 6.2E-73 T 14-10-2018 LH59_18210 833f8486a377824bb1ee184edb45645a 433 Pfam PF07690 Major Facilitator Superfamily 280 427 1.9E-11 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_18210 833f8486a377824bb1ee184edb45645a 433 ProSitePatterns PS00217 Sugar transport proteins signature 2. 127 152 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 LH59_18210 833f8486a377824bb1ee184edb45645a 433 SUPERFAMILY SSF103473 8 425 4.32E-70 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_22725 51c90045c96b1378d6170f61118eadbc 351 Gene3D G3DSA:2.40.10.240 66 161 6.9E-111 T 14-10-2018 LH59_22725 51c90045c96b1378d6170f61118eadbc 351 SUPERFAMILY SSF111337 5 346 1.14E-129 T 14-10-2018 IPR036100 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA superfamily GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 LH59_22725 51c90045c96b1378d6170f61118eadbc 351 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 5 346 2.6E-131 T 14-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 LH59_22725 51c90045c96b1378d6170f61118eadbc 351 Gene3D G3DSA:3.40.1780.10 17 346 6.9E-111 T 14-10-2018 LH59_22725 51c90045c96b1378d6170f61118eadbc 351 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 4 347 45.455 T 14-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 LH59_22725 51c90045c96b1378d6170f61118eadbc 351 Pfam PF02547 Queuosine biosynthesis protein 6 346 7.6E-131 T 14-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 LH59_16180 b22e891dcb83ecf704cee262193729e1 507 Gene3D G3DSA:3.90.1300.10 4 472 2.8E-134 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_16180 b22e891dcb83ecf704cee262193729e1 507 SUPERFAMILY SSF75304 7 463 1.44E-126 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_16180 b22e891dcb83ecf704cee262193729e1 507 Pfam PF01425 Amidase 28 452 2.4E-95 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_09990 3030d97fe684e3a76ce191ccb1826903 779 SUPERFAMILY SSF82866 190 402 1.15E-14 T 14-10-2018 LH59_09990 3030d97fe684e3a76ce191ccb1826903 779 SUPERFAMILY SSF82866 606 769 1.83E-18 T 14-10-2018 LH59_19560 72890ff310e824e5cc672fe8c7996b8a 410 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 8 394 5.3E-118 T 14-10-2018 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 LH59_07010 1d244326c66e798a4758d76660604823 93 Pfam PF12365 Protein of unknown function (DUF3649) 60 85 1.8E-11 T 14-10-2018 IPR022109 Protein of unknown function DUF3649 LH59_23420 5c08ed1accf4d05ef41f433adcae29e7 132 SUPERFAMILY SSF81901 41 117 2.62E-7 T 14-10-2018 LH59_23420 5c08ed1accf4d05ef41f433adcae29e7 132 Gene3D G3DSA:1.25.40.10 21 120 6.3E-9 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_14395 c73a58d65ba75a20ba38c1185becf63e 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 321 6.9E-58 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_14395 c73a58d65ba75a20ba38c1185becf63e 324 Gene3D G3DSA:3.40.190.10 128 250 4.2E-90 T 14-10-2018 LH59_14395 c73a58d65ba75a20ba38c1185becf63e 324 Gene3D G3DSA:3.40.190.150 32 314 4.2E-90 T 14-10-2018 LH59_14395 c73a58d65ba75a20ba38c1185becf63e 324 PIRSF PIRSF017082 1 324 7.4E-102 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_14395 c73a58d65ba75a20ba38c1185becf63e 324 SUPERFAMILY SSF53850 115 289 7.19E-12 T 14-10-2018 LH59_11290 490bd69e61f1dba151cb8dab5deaf708 253 Gene3D G3DSA:1.20.140.160 78 238 1.4E-41 T 14-10-2018 LH59_11290 490bd69e61f1dba151cb8dab5deaf708 253 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 6 235 1.5E-32 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 LH59_11290 490bd69e61f1dba151cb8dab5deaf708 253 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 9 236 5.6E-79 T 14-10-2018 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 LH59_11290 490bd69e61f1dba151cb8dab5deaf708 253 Gene3D G3DSA:1.10.1740.10 2 76 3.8E-28 T 14-10-2018 LH59_11290 490bd69e61f1dba151cb8dab5deaf708 253 PIRSF PIRSF000770 3 252 8.6E-33 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 LH59_11290 490bd69e61f1dba151cb8dab5deaf708 253 SUPERFAMILY SSF88946 7 79 1.22E-22 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 LH59_11290 490bd69e61f1dba151cb8dab5deaf708 253 Hamap MF_00962 RNA polymerase sigma factor FliA [fliA]. 1 238 62.14 T 14-10-2018 IPR028617 RNA polymerase sigma factor FliA GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 LH59_11290 490bd69e61f1dba151cb8dab5deaf708 253 Pfam PF04542 Sigma-70 region 2 10 79 1.8E-16 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 LH59_11290 490bd69e61f1dba151cb8dab5deaf708 253 Pfam PF04545 Sigma-70, region 4 184 232 6.3E-14 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 LH59_11290 490bd69e61f1dba151cb8dab5deaf708 253 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 34 47 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 LH59_11290 490bd69e61f1dba151cb8dab5deaf708 253 SUPERFAMILY SSF88659 162 241 1.59E-18 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like LH59_11290 490bd69e61f1dba151cb8dab5deaf708 253 PRINTS PR00046 Major sigma-70 factor signature 205 220 1.9E-11 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 LH59_11290 490bd69e61f1dba151cb8dab5deaf708 253 PRINTS PR00046 Major sigma-70 factor signature 58 66 1.9E-11 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 LH59_11290 490bd69e61f1dba151cb8dab5deaf708 253 PRINTS PR00046 Major sigma-70 factor signature 188 200 1.9E-11 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 LH59_11290 490bd69e61f1dba151cb8dab5deaf708 253 PRINTS PR00046 Major sigma-70 factor signature 34 47 1.9E-11 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 LH59_11290 490bd69e61f1dba151cb8dab5deaf708 253 PRINTS PR00046 Major sigma-70 factor signature 220 231 1.9E-11 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 LH59_11290 490bd69e61f1dba151cb8dab5deaf708 253 SUPERFAMILY SSF88659 80 145 1.09E-15 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like LH59_11290 490bd69e61f1dba151cb8dab5deaf708 253 Pfam PF04539 Sigma-70 region 3 87 142 4.7E-11 T 14-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 LH59_03100 9b0803983cd29aab92baa88d792d2fb5 277 Gene3D G3DSA:3.60.21.10 4 275 1.7E-73 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like LH59_03100 9b0803983cd29aab92baa88d792d2fb5 277 PIRSF PIRSF000903 3 274 1.4E-103 T 14-10-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 LH59_03100 9b0803983cd29aab92baa88d792d2fb5 277 SUPERFAMILY SSF56300 2 258 2.81E-51 T 14-10-2018 LH59_03100 9b0803983cd29aab92baa88d792d2fb5 277 TIGRFAM TIGR00668 apaH: bis(5'-nucleosyl)-tetraphosphatase (symmetrical) 5 266 6.5E-74 T 14-10-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 LH59_03100 9b0803983cd29aab92baa88d792d2fb5 277 Pfam PF00149 Calcineurin-like phosphoesterase 4 142 1.6E-8 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 LH59_03100 9b0803983cd29aab92baa88d792d2fb5 277 Hamap MF_00199 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical [apaH]. 3 271 43.698 T 14-10-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 LH59_18350 6e83d556bed02b6fd93c48ac37310b1b 305 Gene3D G3DSA:2.120.10.30 39 303 6.8E-72 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like LH59_18350 6e83d556bed02b6fd93c48ac37310b1b 305 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 45 282 4.8E-45 T 14-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region LH59_18350 6e83d556bed02b6fd93c48ac37310b1b 305 SUPERFAMILY SSF63829 41 299 3.49E-64 T 14-10-2018 LH59_18350 6e83d556bed02b6fd93c48ac37310b1b 305 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 223 240 1.4E-8 T 14-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) LH59_18350 6e83d556bed02b6fd93c48ac37310b1b 305 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 266 284 1.4E-8 T 14-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) LH59_18350 6e83d556bed02b6fd93c48ac37310b1b 305 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 162 184 1.4E-8 T 14-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) LH59_09125 3480e52bda7e5617e27f54bf759396e5 250 Gene3D G3DSA:3.40.190.10 25 245 2.5E-61 T 14-10-2018 LH59_09125 3480e52bda7e5617e27f54bf759396e5 250 SUPERFAMILY SSF53850 1 248 2.8E-63 T 14-10-2018 LH59_09125 3480e52bda7e5617e27f54bf759396e5 250 SMART SM00079 25 250 6.0E-4 T 14-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 LH59_09125 3480e52bda7e5617e27f54bf759396e5 250 Gene3D G3DSA:3.40.190.10 113 208 2.5E-61 T 14-10-2018 LH59_09125 3480e52bda7e5617e27f54bf759396e5 250 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 26 247 5.1E-58 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_09125 3480e52bda7e5617e27f54bf759396e5 250 SMART SM00062 25 250 1.2E-48 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_13515 842049e93a16c2c26d430f670b1cf61e 269 Pfam PF00005 ABC transporter 31 170 9.8E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_13515 842049e93a16c2c26d430f670b1cf61e 269 Gene3D G3DSA:3.40.50.300 8 266 2.4E-61 T 14-10-2018 LH59_13515 842049e93a16c2c26d430f670b1cf61e 269 SUPERFAMILY SSF52540 30 241 1.94E-67 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_13515 842049e93a16c2c26d430f670b1cf61e 269 SMART SM00382 40 221 5.0E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_13515 842049e93a16c2c26d430f670b1cf61e 269 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_21250 d9b8745cedecc3d4f8e2abb04e42b1c2 227 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 11 212 5.2E-71 T 14-10-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 LH59_21250 d9b8745cedecc3d4f8e2abb04e42b1c2 227 SUPERFAMILY SSF161098 3 214 2.09E-51 T 14-10-2018 IPR035906 MetI-like superfamily LH59_21250 d9b8745cedecc3d4f8e2abb04e42b1c2 227 Gene3D G3DSA:1.10.3720.10 1 216 6.5E-60 T 14-10-2018 IPR035906 MetI-like superfamily LH59_21250 d9b8745cedecc3d4f8e2abb04e42b1c2 227 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 24 211 9.8E-21 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_23980 9a80e30e44f3cb532aa2e081408bfa43 323 Gene3D G3DSA:3.40.50.720 106 303 5.9E-109 T 14-10-2018 LH59_23980 9a80e30e44f3cb532aa2e081408bfa43 323 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 113 287 4.9E-52 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 LH59_23980 9a80e30e44f3cb532aa2e081408bfa43 323 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 17 318 2.9E-15 T 14-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 LH59_23980 9a80e30e44f3cb532aa2e081408bfa43 323 SUPERFAMILY SSF51735 106 287 6.51E-51 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_23980 9a80e30e44f3cb532aa2e081408bfa43 323 Gene3D G3DSA:3.40.50.720 3 311 5.9E-109 T 14-10-2018 LH59_23980 9a80e30e44f3cb532aa2e081408bfa43 323 SUPERFAMILY SSF52283 1 138 1.25E-19 T 14-10-2018 LH59_16665 d59a39d0e3a285d0ff22f896d55d66bf 547 PIRSF PIRSF000137 1 539 1.3E-151 T 14-10-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 LH59_16665 d59a39d0e3a285d0ff22f896d55d66bf 547 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 254 268 - T 14-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 LH59_16665 d59a39d0e3a285d0ff22f896d55d66bf 547 SUPERFAMILY SSF51905 3 533 2.16E-92 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_16665 d59a39d0e3a285d0ff22f896d55d66bf 547 SUPERFAMILY SSF54373 290 473 1.28E-57 T 14-10-2018 LH59_16665 d59a39d0e3a285d0ff22f896d55d66bf 547 Gene3D G3DSA:3.50.50.60 4 529 5.6E-175 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_16665 d59a39d0e3a285d0ff22f896d55d66bf 547 Pfam PF05199 GMC oxidoreductase 387 525 2.3E-39 T 14-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 LH59_16665 d59a39d0e3a285d0ff22f896d55d66bf 547 Gene3D G3DSA:3.30.560.10 42 468 5.6E-175 T 14-10-2018 LH59_16665 d59a39d0e3a285d0ff22f896d55d66bf 547 Pfam PF00732 GMC oxidoreductase 4 295 5.5E-86 T 14-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 LH59_06345 a1bebf8631be66a2ad98c3f5c77cb4b8 404 SUPERFAMILY SSF53822 32 402 3.26E-90 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_06345 a1bebf8631be66a2ad98c3f5c77cb4b8 404 Gene3D G3DSA:3.40.50.2300 151 282 6.4E-114 T 14-10-2018 LH59_06345 a1bebf8631be66a2ad98c3f5c77cb4b8 404 Gene3D G3DSA:3.40.50.2300 32 333 6.4E-114 T 14-10-2018 LH59_06345 a1bebf8631be66a2ad98c3f5c77cb4b8 404 Pfam PF13458 Periplasmic binding protein 32 367 4.9E-90 T 14-10-2018 IPR028081 Leucine-binding protein domain LH59_14945 8f251b4d9848f33ec08b728964624f1b 473 Gene3D G3DSA:2.20.200.10 105 359 3.0E-122 T 14-10-2018 LH59_14945 8f251b4d9848f33ec08b728964624f1b 473 Gene3D G3DSA:1.20.1600.10 58 471 3.0E-122 T 14-10-2018 LH59_14945 8f251b4d9848f33ec08b728964624f1b 473 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 10 470 1.5E-91 T 14-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 LH59_14945 8f251b4d9848f33ec08b728964624f1b 473 SUPERFAMILY SSF56954 3 472 2.88E-98 T 14-10-2018 LH59_14945 8f251b4d9848f33ec08b728964624f1b 473 Pfam PF02321 Outer membrane efflux protein 68 259 5.1E-25 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 LH59_14945 8f251b4d9848f33ec08b728964624f1b 473 Pfam PF02321 Outer membrane efflux protein 290 463 9.0E-22 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 LH59_20490 36d43129fa810d5cc366f7ed31a464a9 181 SUPERFAMILY SSF54909 5 107 9.84E-19 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel LH59_20490 36d43129fa810d5cc366f7ed31a464a9 181 Gene3D G3DSA:3.30.70.100 9 98 1.0E-5 T 14-10-2018 LH59_09210 ec059559c5601f1b89a42bb76213bdbe 300 Gene3D G3DSA:3.30.479.30 51 187 7.2E-18 T 14-10-2018 LH59_09210 ec059559c5601f1b89a42bb76213bdbe 300 SMART SM00244 20 185 7.5E-26 T 14-10-2018 IPR001107 Band 7 domain LH59_09210 ec059559c5601f1b89a42bb76213bdbe 300 TIGRFAM TIGR01932 hflC: HflC protein 145 285 2.3E-46 T 14-10-2018 IPR010200 HflC GO:0016021|GO:0052547 LH59_09210 ec059559c5601f1b89a42bb76213bdbe 300 SUPERFAMILY SSF117892 54 191 8.63E-25 T 14-10-2018 IPR036013 Band 7/SPFH domain superfamily LH59_09210 ec059559c5601f1b89a42bb76213bdbe 300 Pfam PF01145 SPFH domain / Band 7 family 24 196 1.7E-25 T 14-10-2018 IPR001107 Band 7 domain LH59_09210 ec059559c5601f1b89a42bb76213bdbe 300 PIRSF PIRSF005651 1 293 1.5E-88 T 14-10-2018 IPR010200 HflC GO:0016021|GO:0052547 LH59_06495 477461d6916e6e2cac664c158980064d 328 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 116 193 1.4E-34 T 14-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 LH59_06495 477461d6916e6e2cac664c158980064d 328 SUPERFAMILY SSF53901 5 327 1.44E-66 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_06495 477461d6916e6e2cac664c158980064d 328 Gene3D G3DSA:3.40.47.10 4 328 1.1E-124 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_06495 477461d6916e6e2cac664c158980064d 328 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 6 328 68.354 T 14-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 LH59_06495 477461d6916e6e2cac664c158980064d 328 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 239 327 8.9E-34 T 14-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 LH59_06495 477461d6916e6e2cac664c158980064d 328 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 7 328 8.7E-120 T 14-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 LH59_26590 eb0c557c06a974c6566e2f831939cc9d 41 TIGRFAM TIGR02106 cyd_oper_ybgT: cyd operon protein YbgT 1 30 5.3E-20 T 14-10-2018 IPR011724 Cyd operon protein YbgT MetaCyc: PWY-7545 LH59_26590 eb0c557c06a974c6566e2f831939cc9d 41 Pfam PF08173 Membrane bound YbgT-like protein 1 27 5.0E-16 T 14-10-2018 IPR012994 Membrane bound YbgT-like LH59_11680 dde5249e3bb22a912d96fe8e85402c1d 443 Gene3D G3DSA:2.30.42.10 124 217 4.3E-12 T 14-10-2018 LH59_11680 dde5249e3bb22a912d96fe8e85402c1d 443 SUPERFAMILY SSF50156 84 180 3.81E-15 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 LH59_11680 dde5249e3bb22a912d96fe8e85402c1d 443 SMART SM00228 112 184 4.6E-5 T 14-10-2018 IPR001478 PDZ domain GO:0005515 LH59_11680 dde5249e3bb22a912d96fe8e85402c1d 443 SMART SM00228 208 275 0.0043 T 14-10-2018 IPR001478 PDZ domain GO:0005515 LH59_11680 dde5249e3bb22a912d96fe8e85402c1d 443 Pfam PF02163 Peptidase family M50 7 428 1.1E-75 T 14-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 LH59_11680 dde5249e3bb22a912d96fe8e85402c1d 443 Pfam PF13180 PDZ domain 125 167 1.3E-6 T 14-10-2018 IPR001478 PDZ domain GO:0005515 LH59_11680 dde5249e3bb22a912d96fe8e85402c1d 443 Pfam PF13180 PDZ domain 217 283 1.0E-6 T 14-10-2018 IPR001478 PDZ domain GO:0005515 LH59_11680 dde5249e3bb22a912d96fe8e85402c1d 443 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 2 442 2.8E-110 T 14-10-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 LH59_11680 dde5249e3bb22a912d96fe8e85402c1d 443 Gene3D G3DSA:2.30.42.10 218 303 2.1E-18 T 14-10-2018 LH59_11680 dde5249e3bb22a912d96fe8e85402c1d 443 SUPERFAMILY SSF50156 218 284 5.52E-13 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 LH59_22800 5d11557cd43d78252e407ae570cc1234 335 Pfam PF00248 Aldo/keto reductase family 5 309 9.7E-65 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain LH59_22800 5d11557cd43d78252e407ae570cc1234 335 Gene3D G3DSA:3.20.20.100 1 315 2.3E-100 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily LH59_22800 5d11557cd43d78252e407ae570cc1234 335 SUPERFAMILY SSF51430 3 309 6.81E-86 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily LH59_12795 10837a31794355ac08b7b8a750488e7b 325 Gene3D G3DSA:3.40.190.150 31 315 2.4E-104 T 14-10-2018 LH59_12795 10837a31794355ac08b7b8a750488e7b 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 322 6.3E-84 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_12795 10837a31794355ac08b7b8a750488e7b 325 SUPERFAMILY SSF53850 112 280 2.35E-14 T 14-10-2018 LH59_12795 10837a31794355ac08b7b8a750488e7b 325 Gene3D G3DSA:3.40.190.10 129 250 2.4E-104 T 14-10-2018 LH59_12795 10837a31794355ac08b7b8a750488e7b 325 PIRSF PIRSF017082 1 324 2.6E-80 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_15365 66b18430026822f17109306a757834be 405 Gene3D G3DSA:1.25.40.10 9 224 1.6E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_15365 66b18430026822f17109306a757834be 405 SUPERFAMILY SSF48452 28 133 1.48E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_24610 1d2c76c26952586944942491a4d93bd7 631 Gene3D G3DSA:3.30.1120.80 547 628 5.4E-131 T 14-10-2018 LH59_24610 1d2c76c26952586944942491a4d93bd7 631 PIRSF PIRSF005091 33 610 4.8E-87 T 14-10-2018 IPR012160 Lipoteichoic acid synthase-like LH59_24610 1d2c76c26952586944942491a4d93bd7 631 Pfam PF00884 Sulfatase 272 537 2.6E-39 T 14-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 LH59_24610 1d2c76c26952586944942491a4d93bd7 631 SUPERFAMILY SSF53649 269 580 1.44E-63 T 14-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 LH59_24610 1d2c76c26952586944942491a4d93bd7 631 Gene3D G3DSA:3.40.720.10 266 545 5.4E-131 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 LH59_00395 70f018900e71a2126988bbae5b568a5b 109 SUPERFAMILY SSF160113 4 60 3.4E-16 T 14-10-2018 IPR036913 YegP-like superfamily LH59_00395 70f018900e71a2126988bbae5b568a5b 109 SUPERFAMILY SSF160113 53 107 4.32E-15 T 14-10-2018 IPR036913 YegP-like superfamily LH59_00395 70f018900e71a2126988bbae5b568a5b 109 Pfam PF07411 Domain of unknown function (DUF1508) 11 55 3.7E-19 T 14-10-2018 IPR010879 Domain of unknown function DUF1508 LH59_00395 70f018900e71a2126988bbae5b568a5b 109 Pfam PF07411 Domain of unknown function (DUF1508) 61 107 8.6E-21 T 14-10-2018 IPR010879 Domain of unknown function DUF1508 LH59_00395 70f018900e71a2126988bbae5b568a5b 109 Gene3D G3DSA:2.30.29.80 1 109 3.3E-45 T 14-10-2018 LH59_24330 0999fb196529b753d8c5992ea9f96cb4 183 Pfam PF06052 3-hydroxyanthranilic acid dioxygenase 6 154 1.0E-44 T 14-10-2018 IPR010329 3-hydroxyanthranilic acid dioxygenase GO:0000334|GO:0005506|GO:0055114 KEGG: 00380+1.13.11.6|MetaCyc: PWY-5647|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-6505|Reactome: R-HSA-71240 LH59_24330 0999fb196529b753d8c5992ea9f96cb4 183 TIGRFAM TIGR03037 anthran_nbaC: 3-hydroxyanthranilate 3,4-dioxygenase 8 166 1.6E-77 T 14-10-2018 IPR010329 3-hydroxyanthranilic acid dioxygenase GO:0000334|GO:0005506|GO:0055114 KEGG: 00380+1.13.11.6|MetaCyc: PWY-5647|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-6505|Reactome: R-HSA-71240 LH59_24330 0999fb196529b753d8c5992ea9f96cb4 183 Gene3D G3DSA:2.60.120.10 9 174 1.0E-63 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_24330 0999fb196529b753d8c5992ea9f96cb4 183 SUPERFAMILY SSF51182 5 172 7.97E-52 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_24330 0999fb196529b753d8c5992ea9f96cb4 183 Hamap MF_00825 3-hydroxyanthranilate 3,4-dioxygenase [nbaC]. 4 172 33.317 T 14-10-2018 IPR010329 3-hydroxyanthranilic acid dioxygenase GO:0000334|GO:0005506|GO:0055114 KEGG: 00380+1.13.11.6|MetaCyc: PWY-5647|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-6505|Reactome: R-HSA-71240 LH59_16310 e4820112c0159d289e0c0abe08a7653e 142 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 124 3.4E-12 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain LH59_16310 e4820112c0159d289e0c0abe08a7653e 142 Gene3D G3DSA:3.10.180.10 5 130 5.0E-34 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_16310 e4820112c0159d289e0c0abe08a7653e 142 SUPERFAMILY SSF54593 12 130 3.22E-23 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_07350 561b36cfb96459592c575d3e51ad38d1 385 SUPERFAMILY SSF53955 64 380 3.8E-75 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily LH59_07350 561b36cfb96459592c575d3e51ad38d1 385 Gene3D G3DSA:1.10.8.350 76 249 1.3E-87 T 14-10-2018 LH59_07350 561b36cfb96459592c575d3e51ad38d1 385 Pfam PF13406 Transglycosylase SLT domain 74 376 3.3E-82 T 14-10-2018 IPR031304 Transglycosylase SLT domain 2 LH59_07350 561b36cfb96459592c575d3e51ad38d1 385 TIGRFAM TIGR02282 MltB: lytic murein transglycosylase B 78 379 3.4E-108 T 14-10-2018 IPR011757 Lytic transglycosylase MltB LH59_07350 561b36cfb96459592c575d3e51ad38d1 385 Gene3D G3DSA:1.10.530.10 114 379 1.3E-87 T 14-10-2018 LH59_19725 9fb1a51249506088058e140d561e8228 509 Gene3D G3DSA:1.20.1250.20 266 435 1.8E-11 T 14-10-2018 LH59_19725 9fb1a51249506088058e140d561e8228 509 Gene3D G3DSA:1.20.1720.10 20 264 1.9E-43 T 14-10-2018 LH59_19725 9fb1a51249506088058e140d561e8228 509 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 18 499 2.4E-133 T 14-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 LH59_19725 9fb1a51249506088058e140d561e8228 509 Pfam PF07690 Major Facilitator Superfamily 24 416 5.2E-50 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_19725 9fb1a51249506088058e140d561e8228 509 SUPERFAMILY SSF103473 8 504 8.11E-60 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_25325 8c91feaa6030431da3b0774e433387ac 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 67 4.6E-15 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_25325 8c91feaa6030431da3b0774e433387ac 303 SUPERFAMILY SSF53850 93 298 4.06E-40 T 14-10-2018 LH59_25325 8c91feaa6030431da3b0774e433387ac 303 Gene3D G3DSA:3.40.190.290 95 298 2.7E-38 T 14-10-2018 LH59_25325 8c91feaa6030431da3b0774e433387ac 303 Pfam PF03466 LysR substrate binding domain 92 296 7.5E-36 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_25325 8c91feaa6030431da3b0774e433387ac 303 SUPERFAMILY SSF46785 5 116 1.96E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_25325 8c91feaa6030431da3b0774e433387ac 303 Gene3D G3DSA:1.10.10.10 6 94 1.2E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_02550 b173e30584d7134375ea34b6053d9169 242 SUPERFAMILY SSF48008 104 236 5.75E-28 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_02550 b173e30584d7134375ea34b6053d9169 242 SMART SM00895 106 232 1.9E-22 T 14-10-2018 IPR011711 GntR, C-terminal LH59_02550 b173e30584d7134375ea34b6053d9169 242 Pfam PF07729 FCD domain 106 232 2.8E-23 T 14-10-2018 IPR011711 GntR, C-terminal LH59_02550 b173e30584d7134375ea34b6053d9169 242 Gene3D G3DSA:1.10.10.10 21 93 4.4E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_02550 b173e30584d7134375ea34b6053d9169 242 SUPERFAMILY SSF46785 21 88 5.9E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_02550 b173e30584d7134375ea34b6053d9169 242 SMART SM00345 25 84 3.1E-20 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_02550 b173e30584d7134375ea34b6053d9169 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 58 74 1.2E-9 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_02550 b173e30584d7134375ea34b6053d9169 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 58 1.2E-9 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_02550 b173e30584d7134375ea34b6053d9169 242 Gene3D G3DSA:1.20.120.530 101 237 1.3E-28 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_02550 b173e30584d7134375ea34b6053d9169 242 Pfam PF00392 Bacterial regulatory proteins, gntR family 22 84 1.4E-19 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_10300 7db4e64f31b42ae391e30e5f7eaa249e 355 SUPERFAMILY SSF46689 303 353 2.11E-6 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_10300 7db4e64f31b42ae391e30e5f7eaa249e 355 Pfam PF14525 AraC-binding-like domain 53 230 1.8E-43 T 14-10-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like LH59_10300 7db4e64f31b42ae391e30e5f7eaa249e 355 SMART SM00342 267 351 2.3E-27 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_10300 7db4e64f31b42ae391e30e5f7eaa249e 355 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 304 347 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 LH59_10300 7db4e64f31b42ae391e30e5f7eaa249e 355 SUPERFAMILY SSF46689 251 301 3.65E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_10300 7db4e64f31b42ae391e30e5f7eaa249e 355 Pfam PF12833 Helix-turn-helix domain 273 352 2.0E-26 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_10300 7db4e64f31b42ae391e30e5f7eaa249e 355 Gene3D G3DSA:1.10.10.60 251 354 1.5E-34 T 14-10-2018 LH59_13985 a5395a1f43a8139ab9df30cf8113a7b4 233 SMART SM00945 67 181 5.5E-33 T 14-10-2018 IPR016103 ProQ/FinO domain LH59_13985 a5395a1f43a8139ab9df30cf8113a7b4 233 Pfam PF04352 ProQ/FINO family 71 172 3.7E-31 T 14-10-2018 IPR016103 ProQ/FinO domain LH59_13985 a5395a1f43a8139ab9df30cf8113a7b4 233 Gene3D G3DSA:1.10.1710.10 14 174 3.9E-19 T 14-10-2018 IPR036442 ProQ/FinO domain superfamily LH59_13985 a5395a1f43a8139ab9df30cf8113a7b4 233 SUPERFAMILY SSF48657 47 172 4.19E-31 T 14-10-2018 IPR036442 ProQ/FinO domain superfamily LH59_07235 fb7135b7e4fd9206263538a18b92f589 297 SUPERFAMILY SSF160240 214 286 2.49E-7 T 14-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 LH59_07235 fb7135b7e4fd9206263538a18b92f589 297 Pfam PF01545 Cation efflux family 18 209 1.9E-42 T 14-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 LH59_07235 fb7135b7e4fd9206263538a18b92f589 297 SUPERFAMILY SSF161111 16 210 2.22E-54 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily LH59_07235 fb7135b7e4fd9206263538a18b92f589 297 Gene3D G3DSA:1.20.1510.10 15 209 5.1E-44 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily LH59_07235 fb7135b7e4fd9206263538a18b92f589 297 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 15 288 1.3E-84 T 14-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 LH59_26610 124f45d36c3d67655e502d48eee2a448 405 Hamap MF_01643 Formate-dependent phosphoribosylglycinamide formyltransferase [purT]. 13 403 50.518 T 14-10-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 LH59_26610 124f45d36c3d67655e502d48eee2a448 405 SUPERFAMILY SSF52440 8 118 1.01E-31 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily LH59_26610 124f45d36c3d67655e502d48eee2a448 405 SUPERFAMILY SSF51246 331 402 2.35E-16 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 LH59_26610 124f45d36c3d67655e502d48eee2a448 405 Gene3D G3DSA:3.30.470.20 204 404 3.2E-61 T 14-10-2018 LH59_26610 124f45d36c3d67655e502d48eee2a448 405 TIGRFAM TIGR01142 purT: phosphoribosylglycinamide formyltransferase 2 19 403 1.2E-171 T 14-10-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 LH59_26610 124f45d36c3d67655e502d48eee2a448 405 Pfam PF01370 NAD dependent epimerase/dehydratase family 24 86 4.6E-5 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 LH59_26610 124f45d36c3d67655e502d48eee2a448 405 Gene3D G3DSA:3.40.50.20 7 128 6.1E-52 T 14-10-2018 LH59_26610 124f45d36c3d67655e502d48eee2a448 405 Pfam PF02222 ATP-grasp domain 129 306 8.1E-53 T 14-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type LH59_26610 124f45d36c3d67655e502d48eee2a448 405 Gene3D G3DSA:3.30.1490.20 129 203 5.1E-31 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 LH59_26610 124f45d36c3d67655e502d48eee2a448 405 SUPERFAMILY SSF56059 119 325 7.95E-55 T 14-10-2018 LH59_14495 0287ff2e2f94006856e6ec2bb0dbd428 338 ProSitePatterns PS01276 Peptidase family U32 signature. 168 186 - T 14-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 LH59_14495 0287ff2e2f94006856e6ec2bb0dbd428 338 Pfam PF01136 Peptidase family U32 83 337 2.1E-64 T 14-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 LH59_02615 1a60ae19f01dfff5a7f10e1c60c6c8ee 229 Pfam PF00557 Metallopeptidase family M24 21 220 7.0E-12 T 14-10-2018 IPR000994 Peptidase M24 LH59_02615 1a60ae19f01dfff5a7f10e1c60c6c8ee 229 Gene3D G3DSA:3.90.230.10 17 226 7.9E-12 T 14-10-2018 LH59_02615 1a60ae19f01dfff5a7f10e1c60c6c8ee 229 SUPERFAMILY SSF55920 18 222 6.8E-23 T 14-10-2018 IPR036005 Creatinase/aminopeptidase-like LH59_22425 da9744b11d3d4be3dc03f9e3269b98d1 319 SUPERFAMILY SSF53850 100 313 2.58E-29 T 14-10-2018 LH59_22425 da9744b11d3d4be3dc03f9e3269b98d1 319 Gene3D G3DSA:3.40.190.10 176 280 2.9E-31 T 14-10-2018 LH59_22425 da9744b11d3d4be3dc03f9e3269b98d1 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 50 6.1E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_22425 da9744b11d3d4be3dc03f9e3269b98d1 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 50 61 6.1E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_22425 da9744b11d3d4be3dc03f9e3269b98d1 319 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 40 6.1E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_22425 da9744b11d3d4be3dc03f9e3269b98d1 319 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 15 73 4.6E-19 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_22425 da9744b11d3d4be3dc03f9e3269b98d1 319 Pfam PF03466 LysR substrate binding domain 98 308 2.5E-24 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_22425 da9744b11d3d4be3dc03f9e3269b98d1 319 Gene3D G3DSA:1.10.10.10 2 103 4.3E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_22425 da9744b11d3d4be3dc03f9e3269b98d1 319 Gene3D G3DSA:3.40.190.10 104 292 2.9E-31 T 14-10-2018 LH59_22425 da9744b11d3d4be3dc03f9e3269b98d1 319 SUPERFAMILY SSF46785 11 121 9.25E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_22605 3f7f36af278f6155af3656abfc33d927 243 SUPERFAMILY SSF75217 74 242 1.66E-48 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases LH59_22605 3f7f36af278f6155af3656abfc33d927 243 Gene3D G3DSA:3.40.1280.10 73 243 6.9E-57 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal LH59_22605 3f7f36af278f6155af3656abfc33d927 243 Gene3D G3DSA:2.40.240.20 1 67 3.1E-19 T 14-10-2018 LH59_22605 3f7f36af278f6155af3656abfc33d927 243 SUPERFAMILY SSF88697 3 55 8.78E-13 T 14-10-2018 IPR015947 PUA-like superfamily LH59_22605 3f7f36af278f6155af3656abfc33d927 243 PIRSF PIRSF015601 2 243 5.2E-51 T 14-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 LH59_22605 3f7f36af278f6155af3656abfc33d927 243 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 16 241 4.0E-48 T 14-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 LH59_22605 3f7f36af278f6155af3656abfc33d927 243 Pfam PF04452 RNA methyltransferase 20 237 6.2E-64 T 14-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 LH59_27010 73f59a29663e2023a094d4b87892262a 367 SUPERFAMILY SSF81891 130 316 5.89E-32 T 14-10-2018 LH59_27010 73f59a29663e2023a094d4b87892262a 367 Gene3D G3DSA:3.30.460.10 1 130 6.2E-29 T 14-10-2018 LH59_27010 73f59a29663e2023a094d4b87892262a 367 Pfam PF01743 Poly A polymerase head domain 12 130 1.0E-16 T 14-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 LH59_27010 73f59a29663e2023a094d4b87892262a 367 Gene3D G3DSA:1.10.3090.10 131 321 8.5E-27 T 14-10-2018 LH59_27010 73f59a29663e2023a094d4b87892262a 367 SUPERFAMILY SSF81301 6 128 4.25E-30 T 14-10-2018 LH59_27010 73f59a29663e2023a094d4b87892262a 367 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 156 217 1.3E-8 T 14-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 LH59_27010 73f59a29663e2023a094d4b87892262a 367 PIRSF PIRSF000813 230 367 1.5E-13 T 14-10-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 LH59_27010 73f59a29663e2023a094d4b87892262a 367 PIRSF PIRSF000813 10 247 1.5E-112 T 14-10-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 LH59_05670 082da669acb4310536f030fa9f240b91 718 Gene3D G3DSA:2.40.50.140 627 698 1.3E-26 T 14-10-2018 LH59_05670 082da669acb4310536f030fa9f240b91 718 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 3 698 30.214 T 14-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 LH59_05670 082da669acb4310536f030fa9f240b91 718 SUPERFAMILY SSF55666 145 236 3.51E-31 T 14-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 LH59_05670 082da669acb4310536f030fa9f240b91 718 Pfam PF00575 S1 RNA binding domain 624 695 1.4E-17 T 14-10-2018 IPR003029 S1 domain GO:0003676 LH59_05670 082da669acb4310536f030fa9f240b91 718 SUPERFAMILY SSF50249 619 707 1.04E-18 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_05670 082da669acb4310536f030fa9f240b91 718 PIRSF PIRSF005499 1 718 3.0E-297 T 14-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 LH59_05670 082da669acb4310536f030fa9f240b91 718 Gene3D G3DSA:3.30.1370.10 555 626 1.1E-20 T 14-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 LH59_05670 082da669acb4310536f030fa9f240b91 718 Gene3D G3DSA:3.30.230.70 233 554 1.6E-117 T 14-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 LH59_05670 082da669acb4310536f030fa9f240b91 718 SUPERFAMILY SSF54791 560 644 1.37E-22 T 14-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 LH59_05670 082da669acb4310536f030fa9f240b91 718 Pfam PF00013 KH domain 562 618 2.8E-11 T 14-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 LH59_05670 082da669acb4310536f030fa9f240b91 718 SMART SM00316 625 695 8.1E-23 T 14-10-2018 IPR022967 RNA-binding domain, S1 LH59_05670 082da669acb4310536f030fa9f240b91 718 SUPERFAMILY SSF46915 239 326 1.33E-15 T 14-10-2018 IPR036456 Polyribonucleotide nucleotidyltransferase, RNA-binding domain superfamily GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 LH59_05670 082da669acb4310536f030fa9f240b91 718 Gene3D G3DSA:3.30.230.70 1 229 2.2E-81 T 14-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 LH59_05670 082da669acb4310536f030fa9f240b91 718 SUPERFAMILY SSF54211 2 144 5.57E-52 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold LH59_05670 082da669acb4310536f030fa9f240b91 718 SUPERFAMILY SSF54211 299 493 3.64E-50 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold LH59_05670 082da669acb4310536f030fa9f240b91 718 Pfam PF01138 3' exoribonuclease family, domain 1 16 144 3.8E-20 T 14-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 LH59_05670 082da669acb4310536f030fa9f240b91 718 Pfam PF01138 3' exoribonuclease family, domain 1 329 461 1.6E-24 T 14-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 LH59_05670 082da669acb4310536f030fa9f240b91 718 SUPERFAMILY SSF55666 458 565 3.51E-28 T 14-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 LH59_05670 082da669acb4310536f030fa9f240b91 718 Pfam PF03725 3' exoribonuclease family, domain 2 466 533 4.9E-5 T 14-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 LH59_05670 082da669acb4310536f030fa9f240b91 718 Pfam PF03725 3' exoribonuclease family, domain 2 147 205 1.5E-11 T 14-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 LH59_05670 082da669acb4310536f030fa9f240b91 718 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 10 696 0.0 T 14-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 LH59_05670 082da669acb4310536f030fa9f240b91 718 SMART SM00322 557 622 1.8E-13 T 14-10-2018 IPR004087 K Homology domain GO:0003676 LH59_05670 082da669acb4310536f030fa9f240b91 718 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 242 325 6.2E-18 T 14-10-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 LH59_25750 4a6a8f3a997b6886274f9822b4805907 300 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 6 292 39.245 T 14-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LH59_25750 4a6a8f3a997b6886274f9822b4805907 300 SUPERFAMILY SSF51569 4 292 1.36E-84 T 14-10-2018 LH59_25750 4a6a8f3a997b6886274f9822b4805907 300 PIRSF PIRSF001365 3 298 4.8E-75 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_25750 4a6a8f3a997b6886274f9822b4805907 300 Gene3D G3DSA:3.20.20.70 3 293 3.2E-89 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_25750 4a6a8f3a997b6886274f9822b4805907 300 PRINTS PR00146 Dihydrodipicolinate synthase signature 40 61 5.4E-16 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_25750 4a6a8f3a997b6886274f9822b4805907 300 PRINTS PR00146 Dihydrodipicolinate synthase signature 76 94 5.4E-16 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_25750 4a6a8f3a997b6886274f9822b4805907 300 PRINTS PR00146 Dihydrodipicolinate synthase signature 108 124 5.4E-16 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_25750 4a6a8f3a997b6886274f9822b4805907 300 PRINTS PR00146 Dihydrodipicolinate synthase signature 133 150 5.4E-16 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_25750 4a6a8f3a997b6886274f9822b4805907 300 Pfam PF00701 Dihydrodipicolinate synthetase family 7 291 1.6E-67 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_25750 4a6a8f3a997b6886274f9822b4805907 300 SMART SM01130 6 294 2.5E-95 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_25750 4a6a8f3a997b6886274f9822b4805907 300 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 10 291 1.2E-67 T 14-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LH59_06825 62cc749b278aa0e3e1b158d50ea47131 555 Pfam PF00501 AMP-binding enzyme 32 446 4.8E-85 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 LH59_06825 62cc749b278aa0e3e1b158d50ea47131 555 Pfam PF13193 AMP-binding enzyme C-terminal domain 455 535 4.4E-23 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain LH59_06825 62cc749b278aa0e3e1b158d50ea47131 555 Gene3D G3DSA:3.40.50.12780 12 442 2.5E-116 T 14-10-2018 LH59_06825 62cc749b278aa0e3e1b158d50ea47131 555 SUPERFAMILY SSF56801 5 547 3.79E-151 T 14-10-2018 LH59_06825 62cc749b278aa0e3e1b158d50ea47131 555 Gene3D G3DSA:3.30.300.30 443 554 5.5E-32 T 14-10-2018 LH59_06825 62cc749b278aa0e3e1b158d50ea47131 555 ProSitePatterns PS00455 Putative AMP-binding domain signature. 189 200 - T 14-10-2018 IPR020845 AMP-binding, conserved site LH59_09060 89628840ee3ba2895e80c64ded152e61 105 Pfam PF00893 Small Multidrug Resistance protein 1 93 1.7E-32 T 14-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 LH59_09060 89628840ee3ba2895e80c64ded152e61 105 SUPERFAMILY SSF103481 5 104 1.18E-20 T 14-10-2018 LH59_09060 89628840ee3ba2895e80c64ded152e61 105 Gene3D G3DSA:1.10.3730.20 1 105 8.7E-33 T 14-10-2018 LH59_06445 72a0698096d8f4027061fc2001987ea7 301 Pfam PF01479 S4 domain 11 57 8.6E-8 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_06445 72a0698096d8f4027061fc2001987ea7 301 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 7 298 1.1E-77 T 14-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 LH59_06445 72a0698096d8f4027061fc2001987ea7 301 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 125 139 - T 14-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 LH59_06445 72a0698096d8f4027061fc2001987ea7 301 Gene3D G3DSA:3.30.2350.10 79 301 2.0E-75 T 14-10-2018 LH59_06445 72a0698096d8f4027061fc2001987ea7 301 SMART SM00363 11 78 3.3E-7 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_06445 72a0698096d8f4027061fc2001987ea7 301 Pfam PF00849 RNA pseudouridylate synthase 87 235 5.2E-31 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 LH59_06445 72a0698096d8f4027061fc2001987ea7 301 SUPERFAMILY SSF55174 10 61 6.92E-9 T 14-10-2018 LH59_06445 72a0698096d8f4027061fc2001987ea7 301 Gene3D G3DSA:3.10.290.10 1 62 3.3E-14 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 LH59_06445 72a0698096d8f4027061fc2001987ea7 301 SUPERFAMILY SSF55120 72 298 2.4E-65 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 LH59_02250 ca99a2c7394e40978111be7e5dec98ee 374 Pfam PF07883 Cupin domain 279 346 1.9E-10 T 14-10-2018 IPR013096 Cupin 2, conserved barrel LH59_02250 ca99a2c7394e40978111be7e5dec98ee 374 Pfam PF07883 Cupin domain 107 174 4.4E-16 T 14-10-2018 IPR013096 Cupin 2, conserved barrel LH59_02250 ca99a2c7394e40978111be7e5dec98ee 374 SUPERFAMILY SSF51182 22 371 6.5E-114 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_02250 ca99a2c7394e40978111be7e5dec98ee 374 Gene3D G3DSA:2.60.120.10 20 374 3.0E-127 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_18365 bf0d00c8f1b644b64ec3b1f4a31c8e82 110 SMART SM00834 1 41 8.0E-15 T 14-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain LH59_18365 bf0d00c8f1b644b64ec3b1f4a31c8e82 110 Pfam PF09723 Zinc ribbon domain 1 39 5.0E-12 T 14-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain LH59_18365 bf0d00c8f1b644b64ec3b1f4a31c8e82 110 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 45 1.9E-15 T 14-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain LH59_05450 4198ce220746c8f81cf6b2747e018097 697 TIGRFAM TIGR03648 Na_symport_lg: probable sodium:solute symporter, VC_2705 subfamily 48 685 1.2E-233 T 14-10-2018 IPR019899 Sodium/solute symporter, VC2705 subfamily LH59_05450 4198ce220746c8f81cf6b2747e018097 697 Pfam PF00474 Sodium:solute symporter family 495 610 9.0E-16 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 LH59_05450 4198ce220746c8f81cf6b2747e018097 697 Pfam PF00474 Sodium:solute symporter family 73 232 1.7E-28 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 LH59_05450 4198ce220746c8f81cf6b2747e018097 697 Pfam PF00474 Sodium:solute symporter family 374 429 3.0E-5 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 LH59_05450 4198ce220746c8f81cf6b2747e018097 697 Gene3D G3DSA:1.20.1730.10 63 267 1.9E-37 T 14-10-2018 IPR038377 Sodium/glucose symporter superfamily LH59_05450 4198ce220746c8f81cf6b2747e018097 697 Gene3D G3DSA:1.20.1730.10 338 674 2.4E-27 T 14-10-2018 IPR038377 Sodium/glucose symporter superfamily LH59_15920 b6d092e85f22dc3a9f7b162c79d84fd0 325 Gene3D G3DSA:3.40.190.150 29 315 3.4E-108 T 14-10-2018 LH59_15920 b6d092e85f22dc3a9f7b162c79d84fd0 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 321 1.8E-87 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_15920 b6d092e85f22dc3a9f7b162c79d84fd0 325 PIRSF PIRSF017082 1 324 2.1E-78 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_15920 b6d092e85f22dc3a9f7b162c79d84fd0 325 SUPERFAMILY SSF53850 112 283 1.99E-12 T 14-10-2018 LH59_15920 b6d092e85f22dc3a9f7b162c79d84fd0 325 Gene3D G3DSA:3.40.190.10 127 250 3.4E-108 T 14-10-2018 LH59_23430 74d016bcd5d388de7ff02f1ae824407a 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 1.7E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_23430 74d016bcd5d388de7ff02f1ae824407a 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 1.7E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_23430 74d016bcd5d388de7ff02f1ae824407a 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 1.7E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_23430 74d016bcd5d388de7ff02f1ae824407a 269 Pfam PF00106 short chain dehydrogenase 6 188 4.0E-48 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_23430 74d016bcd5d388de7ff02f1ae824407a 269 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 188 4.3E-4 T 14-10-2018 LH59_23430 74d016bcd5d388de7ff02f1ae824407a 269 Gene3D G3DSA:3.40.50.720 2 263 1.1E-71 T 14-10-2018 LH59_23430 74d016bcd5d388de7ff02f1ae824407a 269 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LH59_23430 74d016bcd5d388de7ff02f1ae824407a 269 SUPERFAMILY SSF51735 4 223 6.6E-60 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_23430 74d016bcd5d388de7ff02f1ae824407a 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 3.3E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_23430 74d016bcd5d388de7ff02f1ae824407a 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 3.3E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_23430 74d016bcd5d388de7ff02f1ae824407a 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 3.3E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_23430 74d016bcd5d388de7ff02f1ae824407a 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 3.3E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_23430 74d016bcd5d388de7ff02f1ae824407a 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 3.3E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_27290 e1deaa183382787151e1539f41ee821c 348 Gene3D G3DSA:3.40.50.2000 196 347 1.8E-36 T 14-10-2018 LH59_27290 e1deaa183382787151e1539f41ee821c 348 SUPERFAMILY SSF53756 4 345 1.57E-64 T 14-10-2018 LH59_27290 e1deaa183382787151e1539f41ee821c 348 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 78 336 5.2E-72 T 14-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 LH59_27290 e1deaa183382787151e1539f41ee821c 348 TIGRFAM TIGR02193 heptsyl_trn_I: lipopolysaccharide heptosyltransferase I 4 345 9.1E-122 T 14-10-2018 IPR011908 Lipopolysaccharide heptosyltransferase I GO:0008920|GO:0009244 LH59_27290 e1deaa183382787151e1539f41ee821c 348 Gene3D G3DSA:3.40.50.2000 3 162 2.7E-56 T 14-10-2018 LH59_17300 917702b00997bb30c14d1d9f8bbdeb4a 132 Pfam PF01042 Endoribonuclease L-PSP 18 130 1.1E-16 T 14-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 LH59_17300 917702b00997bb30c14d1d9f8bbdeb4a 132 Gene3D G3DSA:3.30.1330.40 3 132 5.3E-31 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 LH59_17300 917702b00997bb30c14d1d9f8bbdeb4a 132 SUPERFAMILY SSF55298 2 131 3.14E-26 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 LH59_06130 02d38a23e593557d7f12cf3d63153063 455 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 371 382 - T 14-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06130 02d38a23e593557d7f12cf3d63153063 455 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 44 444 5.0E-193 T 14-10-2018 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06130 02d38a23e593557d7f12cf3d63153063 455 Pfam PF10531 SLBB domain 272 320 9.8E-13 T 14-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06130 02d38a23e593557d7f12cf3d63153063 455 SUPERFAMILY SSF140490 355 452 3.79E-38 T 14-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06130 02d38a23e593557d7f12cf3d63153063 455 SMART SM00928 358 403 5.0E-25 T 14-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06130 02d38a23e593557d7f12cf3d63153063 455 SUPERFAMILY SSF142019 45 269 1.15E-83 T 14-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06130 02d38a23e593557d7f12cf3d63153063 455 SUPERFAMILY SSF142984 270 353 1.7E-26 T 14-10-2018 LH59_06130 02d38a23e593557d7f12cf3d63153063 455 Gene3D G3DSA:3.40.50.11540 82 259 5.5E-74 T 14-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06130 02d38a23e593557d7f12cf3d63153063 455 Gene3D G3DSA:3.10.20.600 261 355 4.8E-35 T 14-10-2018 LH59_06130 02d38a23e593557d7f12cf3d63153063 455 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 362 443 2.7E-30 T 14-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06130 02d38a23e593557d7f12cf3d63153063 455 Gene3D G3DSA:1.20.1440.230 356 452 2.0E-33 T 14-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06130 02d38a23e593557d7f12cf3d63153063 455 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 77 248 2.7E-46 T 14-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_14790 f365416efb2b016103c625080a86785b 283 SUPERFAMILY SSF46785 4 112 1.02E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_14790 f365416efb2b016103c625080a86785b 283 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 2.8E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_14790 f365416efb2b016103c625080a86785b 283 Gene3D G3DSA:3.40.190.10 164 254 1.4E-37 T 14-10-2018 LH59_14790 f365416efb2b016103c625080a86785b 283 Pfam PF03466 LysR substrate binding domain 90 281 6.0E-17 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_14790 f365416efb2b016103c625080a86785b 283 Gene3D G3DSA:3.40.190.10 97 260 1.4E-37 T 14-10-2018 LH59_14790 f365416efb2b016103c625080a86785b 283 Gene3D G3DSA:1.10.10.10 1 85 8.5E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_14790 f365416efb2b016103c625080a86785b 283 SUPERFAMILY SSF53850 91 282 2.02E-19 T 14-10-2018 LH59_26675 fc1afa26efe4a4bd3b98fe00ffcefa17 318 Gene3D G3DSA:2.40.40.10 87 179 3.3E-32 T 14-10-2018 IPR036908 RlpA-like domain superfamily LH59_26675 fc1afa26efe4a4bd3b98fe00ffcefa17 318 Hamap MF_02071 Endolytic peptidoglycan transglycosylase RlpA [rlpA]. 23 179 23.264 T 14-10-2018 IPR034718 Endolytic peptidoglycan transglycosylase RlpA GO:0016829 LH59_26675 fc1afa26efe4a4bd3b98fe00ffcefa17 318 Pfam PF03330 Lytic transglycolase 88 174 6.2E-23 T 14-10-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain LH59_26675 fc1afa26efe4a4bd3b98fe00ffcefa17 318 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 89 183 1.8E-38 T 14-10-2018 IPR012997 Rare lipoprotein A LH59_26675 fc1afa26efe4a4bd3b98fe00ffcefa17 318 Gene3D G3DSA:3.30.70.1070 242 315 8.6E-9 T 14-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 LH59_26675 fc1afa26efe4a4bd3b98fe00ffcefa17 318 Pfam PF05036 Sporulation related domain 241 306 1.9E-14 T 14-10-2018 IPR007730 Sporulation-like domain GO:0042834 LH59_26675 fc1afa26efe4a4bd3b98fe00ffcefa17 318 SUPERFAMILY SSF50685 91 170 3.31E-6 T 14-10-2018 IPR036908 RlpA-like domain superfamily LH59_26675 fc1afa26efe4a4bd3b98fe00ffcefa17 318 SUPERFAMILY SSF110997 242 307 2.48E-11 T 14-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 LH59_27890 4940cfa76f79a52700673051b99ce02d 91 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 3.6E-24 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27890 4940cfa76f79a52700673051b99ce02d 91 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 3.6E-24 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27890 4940cfa76f79a52700673051b99ce02d 91 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 3.6E-24 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27890 4940cfa76f79a52700673051b99ce02d 91 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 91 1.7E-46 T 14-10-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 LH59_27890 4940cfa76f79a52700673051b99ce02d 91 SUPERFAMILY SSF54570 2 84 1.83E-36 T 14-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27890 4940cfa76f79a52700673051b99ce02d 91 Pfam PF00203 Ribosomal protein S19 3 83 1.3E-37 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27890 4940cfa76f79a52700673051b99ce02d 91 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.976 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27890 4940cfa76f79a52700673051b99ce02d 91 PIRSF PIRSF002144 1 91 1.1E-33 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27890 4940cfa76f79a52700673051b99ce02d 91 Gene3D G3DSA:3.30.860.10 1 91 7.7E-43 T 14-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27890 4940cfa76f79a52700673051b99ce02d 91 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 14-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_20415 53d6545dfe9719b05f06d4d08bf7e93f 253 Gene3D G3DSA:3.30.450.40 83 252 1.1E-28 T 14-10-2018 IPR029016 GAF-like domain superfamily LH59_20415 53d6545dfe9719b05f06d4d08bf7e93f 253 SUPERFAMILY SSF55781 82 250 1.11E-32 T 14-10-2018 LH59_20415 53d6545dfe9719b05f06d4d08bf7e93f 253 SMART SM00346 11 99 4.0E-5 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_20415 53d6545dfe9719b05f06d4d08bf7e93f 253 Gene3D G3DSA:1.10.10.10 10 72 5.5E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_20415 53d6545dfe9719b05f06d4d08bf7e93f 253 Pfam PF01614 Bacterial transcriptional regulator 133 243 1.3E-12 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal LH59_20415 53d6545dfe9719b05f06d4d08bf7e93f 253 SUPERFAMILY SSF46785 13 72 5.55E-10 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_20415 53d6545dfe9719b05f06d4d08bf7e93f 253 Pfam PF09339 IclR helix-turn-helix domain 14 61 5.9E-11 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_10315 77476378410d78d9461b0e12a8372980 331 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 4.9E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10315 77476378410d78d9461b0e12a8372980 331 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 4.9E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10315 77476378410d78d9461b0e12a8372980 331 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 4.9E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10315 77476378410d78d9461b0e12a8372980 331 SUPERFAMILY SSF51735 6 265 3.68E-60 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_10315 77476378410d78d9461b0e12a8372980 331 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 4.5E-22 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10315 77476378410d78d9461b0e12a8372980 331 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 4.5E-22 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10315 77476378410d78d9461b0e12a8372980 331 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 4.5E-22 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10315 77476378410d78d9461b0e12a8372980 331 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 4.5E-22 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10315 77476378410d78d9461b0e12a8372980 331 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 4.5E-22 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10315 77476378410d78d9461b0e12a8372980 331 Gene3D G3DSA:3.40.50.720 1 267 1.2E-62 T 14-10-2018 LH59_10315 77476378410d78d9461b0e12a8372980 331 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LH59_10315 77476378410d78d9461b0e12a8372980 331 Pfam PF00106 short chain dehydrogenase 11 202 6.1E-45 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_11890 4250f58b4373700e14fd93a85fcb3fe7 232 SUPERFAMILY SSF52833 1 84 5.72E-23 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_11890 4250f58b4373700e14fd93a85fcb3fe7 232 Pfam PF02798 Glutathione S-transferase, N-terminal domain 4 81 1.9E-15 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 LH59_11890 4250f58b4373700e14fd93a85fcb3fe7 232 SUPERFAMILY SSF47616 78 207 1.77E-39 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily LH59_11890 4250f58b4373700e14fd93a85fcb3fe7 232 Pfam PF00043 Glutathione S-transferase, C-terminal domain 129 196 7.2E-10 T 14-10-2018 IPR004046 Glutathione S-transferase, C-terminal LH59_11890 4250f58b4373700e14fd93a85fcb3fe7 232 Gene3D G3DSA:3.40.30.10 1 89 5.1E-33 T 14-10-2018 LH59_11890 4250f58b4373700e14fd93a85fcb3fe7 232 Gene3D G3DSA:1.20.1050.10 90 226 1.9E-51 T 14-10-2018 LH59_18585 efa1c7cf19c14ecc7fda0d00d026c64b 365 Gene3D G3DSA:1.10.1040.10 197 351 1.5E-34 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 LH59_18585 efa1c7cf19c14ecc7fda0d00d026c64b 365 Pfam PF02317 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain 187 332 7.3E-29 T 14-10-2018 IPR003421 Opine dehydrogenase GO:0016491|GO:0050662|GO:0055114 LH59_18585 efa1c7cf19c14ecc7fda0d00d026c64b 365 SUPERFAMILY SSF48179 189 361 4.08E-45 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 LH59_18585 efa1c7cf19c14ecc7fda0d00d026c64b 365 Gene3D G3DSA:3.40.50.720 1 195 5.6E-46 T 14-10-2018 LH59_18585 efa1c7cf19c14ecc7fda0d00d026c64b 365 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3 106 8.3E-7 T 14-10-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 LH59_18585 efa1c7cf19c14ecc7fda0d00d026c64b 365 SUPERFAMILY SSF51735 1 147 5.38E-16 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_07285 83932c92f1e704395eaf1da16b597f4b 440 PIRSF PIRSF000505 8 440 1.4E-133 T 14-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 LH59_07285 83932c92f1e704395eaf1da16b597f4b 440 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 18 438 1.3E-135 T 14-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 LH59_07285 83932c92f1e704395eaf1da16b597f4b 440 Gene3D G3DSA:3.65.10.10 247 432 3.2E-129 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 LH59_07285 83932c92f1e704395eaf1da16b597f4b 440 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 13 440 33.103 T 14-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 LH59_07285 83932c92f1e704395eaf1da16b597f4b 440 SUPERFAMILY SSF55205 9 437 5.36E-120 T 14-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 LH59_07285 83932c92f1e704395eaf1da16b597f4b 440 Gene3D G3DSA:3.65.10.10 23 246 3.2E-129 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 LH59_07285 83932c92f1e704395eaf1da16b597f4b 440 ProSitePatterns PS00885 EPSP synthase signature 2. 350 368 - T 14-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 LH59_07285 83932c92f1e704395eaf1da16b597f4b 440 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 14 433 6.7E-117 T 14-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 LH59_07285 83932c92f1e704395eaf1da16b597f4b 440 ProSitePatterns PS00104 EPSP synthase signature 1. 90 104 - T 14-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 LH59_07965 0f9bc236efc017808c1f841c0eecb192 354 SMART SM00382 66 237 2.7E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_07965 0f9bc236efc017808c1f841c0eecb192 354 SUPERFAMILY SSF52540 12 276 1.16E-67 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_07965 0f9bc236efc017808c1f841c0eecb192 354 Hamap MF_00268 Protein RecA [recA]. 13 338 51.823 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 LH59_07965 0f9bc236efc017808c1f841c0eecb192 354 Gene3D G3DSA:3.40.50.300 34 277 6.9E-85 T 14-10-2018 LH59_07965 0f9bc236efc017808c1f841c0eecb192 354 Pfam PF00154 recA bacterial DNA recombination protein 15 277 2.7E-145 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 LH59_07965 0f9bc236efc017808c1f841c0eecb192 354 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 12 333 5.6E-173 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 LH59_07965 0f9bc236efc017808c1f841c0eecb192 354 SUPERFAMILY SSF54752 277 335 1.23E-21 T 14-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal LH59_07965 0f9bc236efc017808c1f841c0eecb192 354 ProSitePatterns PS00321 recA signature. 222 230 - T 14-10-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 LH59_07965 0f9bc236efc017808c1f841c0eecb192 354 Gene3D G3DSA:3.30.250.10 278 351 5.4E-27 T 14-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal LH59_07965 0f9bc236efc017808c1f841c0eecb192 354 PRINTS PR00142 RecA protein signature 219 247 5.0E-84 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 LH59_07965 0f9bc236efc017808c1f841c0eecb192 354 PRINTS PR00142 RecA protein signature 306 323 5.0E-84 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 LH59_07965 0f9bc236efc017808c1f841c0eecb192 354 PRINTS PR00142 RecA protein signature 252 281 5.0E-84 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 LH59_07965 0f9bc236efc017808c1f841c0eecb192 354 PRINTS PR00142 RecA protein signature 102 131 5.0E-84 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 LH59_07965 0f9bc236efc017808c1f841c0eecb192 354 PRINTS PR00142 RecA protein signature 174 203 5.0E-84 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 LH59_07965 0f9bc236efc017808c1f841c0eecb192 354 PRINTS PR00142 RecA protein signature 136 165 5.0E-84 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 LH59_10755 b666c57ad55b74c025241742ad56afd0 329 PIRSF PIRSF006470 2 325 1.1E-70 T 14-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 LH59_10755 b666c57ad55b74c025241742ad56afd0 329 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 29 284 3.9E-71 T 14-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 LH59_10755 b666c57ad55b74c025241742ad56afd0 329 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 29 301 1.7E-73 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 LH59_10755 b666c57ad55b74c025241742ad56afd0 329 Gene3D G3DSA:3.40.190.170 20 329 1.8E-109 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily LH59_20865 46cff9170ddb681601817ab8c30762c8 324 Gene3D G3DSA:3.40.190.10 126 249 6.0E-107 T 14-10-2018 LH59_20865 46cff9170ddb681601817ab8c30762c8 324 PIRSF PIRSF017082 2 324 1.9E-75 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_20865 46cff9170ddb681601817ab8c30762c8 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 320 1.3E-83 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_20865 46cff9170ddb681601817ab8c30762c8 324 Gene3D G3DSA:3.40.190.150 29 314 6.0E-107 T 14-10-2018 LH59_20865 46cff9170ddb681601817ab8c30762c8 324 SUPERFAMILY SSF53850 115 283 2.67E-12 T 14-10-2018 LH59_14020 9a63ceef67273cffb77ab5ebb4a7fe00 227 Gene3D G3DSA:1.10.10.10 122 224 1.6E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_14020 9a63ceef67273cffb77ab5ebb4a7fe00 227 Gene3D G3DSA:3.40.50.2300 1 121 6.6E-37 T 14-10-2018 LH59_14020 9a63ceef67273cffb77ab5ebb4a7fe00 227 SMART SM00862 147 221 1.0E-16 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_14020 9a63ceef67273cffb77ab5ebb4a7fe00 227 SMART SM00448 1 113 9.7E-43 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_14020 9a63ceef67273cffb77ab5ebb4a7fe00 227 SUPERFAMILY SSF46894 125 222 2.72E-20 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LH59_14020 9a63ceef67273cffb77ab5ebb4a7fe00 227 Pfam PF00072 Response regulator receiver domain 3 113 7.6E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_14020 9a63ceef67273cffb77ab5ebb4a7fe00 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 221 1.0E-15 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_14020 9a63ceef67273cffb77ab5ebb4a7fe00 227 SUPERFAMILY SSF52172 1 123 2.99E-39 T 14-10-2018 IPR011006 CheY-like superfamily LH59_06625 b74b664aa68773ca1bc14e905a01df67 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 4.8E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_06625 b74b664aa68773ca1bc14e905a01df67 306 SUPERFAMILY SSF53850 91 288 8.14E-38 T 14-10-2018 LH59_06625 b74b664aa68773ca1bc14e905a01df67 306 Gene3D G3DSA:1.10.10.10 2 84 9.4E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_06625 b74b664aa68773ca1bc14e905a01df67 306 Pfam PF03466 LysR substrate binding domain 89 287 7.1E-34 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_06625 b74b664aa68773ca1bc14e905a01df67 306 Gene3D G3DSA:3.40.190.290 92 287 4.8E-35 T 14-10-2018 LH59_06625 b74b664aa68773ca1bc14e905a01df67 306 SUPERFAMILY SSF46785 2 111 6.21E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_20775 59c866762d8b60ddbddbd8285764db48 496 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 282 436 1.6E-41 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 LH59_20775 59c866762d8b60ddbddbd8285764db48 496 SUPERFAMILY SSF58104 194 473 1.18E-58 T 14-10-2018 LH59_20775 59c866762d8b60ddbddbd8285764db48 496 Gene3D G3DSA:1.10.287.950 177 471 1.1E-65 T 14-10-2018 LH59_20775 59c866762d8b60ddbddbd8285764db48 496 SMART SM00283 222 469 1.1E-61 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 LH59_20775 59c866762d8b60ddbddbd8285764db48 496 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 243 272 7.2E-39 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_20775 59c866762d8b60ddbddbd8285764db48 496 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 349 378 7.2E-39 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_20775 59c866762d8b60ddbddbd8285764db48 496 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 397 426 7.2E-39 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_20775 59c866762d8b60ddbddbd8285764db48 496 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 320 347 7.2E-39 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_26715 244da79824b1d9a189fb69b149dd4158 300 SUPERFAMILY SSF53633 16 299 8.12E-90 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily LH59_26715 244da79824b1d9a189fb69b149dd4158 300 PRINTS PR00474 Glutamate 5-kinase family signature 64 78 4.3E-6 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 LH59_26715 244da79824b1d9a189fb69b149dd4158 300 PRINTS PR00474 Glutamate 5-kinase family signature 199 226 4.3E-6 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 LH59_26715 244da79824b1d9a189fb69b149dd4158 300 PRINTS PR00474 Glutamate 5-kinase family signature 249 269 4.3E-6 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 LH59_26715 244da79824b1d9a189fb69b149dd4158 300 TIGRFAM TIGR00761 argB: acetylglutamate kinase 34 274 2.2E-73 T 14-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 LH59_26715 244da79824b1d9a189fb69b149dd4158 300 Pfam PF00696 Amino acid kinase family 33 276 8.6E-44 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 LH59_26715 244da79824b1d9a189fb69b149dd4158 300 Hamap MF_00082 Acetylglutamate kinase [argB]. 32 292 48.882 T 14-10-2018 IPR037528 Acetylglutamate kinase ArgB GO:0003991|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 LH59_26715 244da79824b1d9a189fb69b149dd4158 300 Gene3D G3DSA:3.40.1160.10 11 300 6.1E-98 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily LH59_26715 244da79824b1d9a189fb69b149dd4158 300 PIRSF PIRSF000728 18 299 1.1E-101 T 14-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 LH59_03570 33431b5ac4912318c721b54a8b43c026 261 Gene3D G3DSA:3.40.50.720 2 258 1.9E-57 T 14-10-2018 LH59_03570 33431b5ac4912318c721b54a8b43c026 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 253 1.2E-87 T 14-10-2018 LH59_03570 33431b5ac4912318c721b54a8b43c026 261 SUPERFAMILY SSF51735 6 254 4.19E-65 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_03570 33431b5ac4912318c721b54a8b43c026 261 PIRSF PIRSF000094 1 260 7.0E-114 T 14-10-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 LH59_03570 33431b5ac4912318c721b54a8b43c026 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 3.2E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_03570 33431b5ac4912318c721b54a8b43c026 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 3.2E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_03570 33431b5ac4912318c721b54a8b43c026 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 3.2E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_03570 33431b5ac4912318c721b54a8b43c026 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 3.2E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_03570 33431b5ac4912318c721b54a8b43c026 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 3.2E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_23755 64321dd71ac3771b9907bdb17c53e1a6 232 Gene3D G3DSA:1.10.10.10 6 105 1.8E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_23755 64321dd71ac3771b9907bdb17c53e1a6 232 Gene3D G3DSA:3.40.250.10 117 220 7.4E-27 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily LH59_23755 64321dd71ac3771b9907bdb17c53e1a6 232 SUPERFAMILY SSF46785 10 109 1.84E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_23755 64321dd71ac3771b9907bdb17c53e1a6 232 ProSitePatterns PS00380 Rhodanese signature 1. 145 156 - T 14-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 LH59_23755 64321dd71ac3771b9907bdb17c53e1a6 232 SUPERFAMILY SSF52821 114 219 4.58E-30 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily LH59_23755 64321dd71ac3771b9907bdb17c53e1a6 232 Pfam PF12840 Helix-turn-helix domain 15 74 2.2E-8 T 14-10-2018 LH59_23755 64321dd71ac3771b9907bdb17c53e1a6 232 Pfam PF00581 Rhodanese-like domain 122 212 2.0E-14 T 14-10-2018 IPR001763 Rhodanese-like domain LH59_23755 64321dd71ac3771b9907bdb17c53e1a6 232 SMART SM00450 120 216 1.0E-20 T 14-10-2018 IPR001763 Rhodanese-like domain LH59_23755 64321dd71ac3771b9907bdb17c53e1a6 232 SMART SM00418 16 94 4.3E-23 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LH59_23755 64321dd71ac3771b9907bdb17c53e1a6 232 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 65 80 8.8E-8 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LH59_23755 64321dd71ac3771b9907bdb17c53e1a6 232 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 50 65 8.8E-8 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LH59_23755 64321dd71ac3771b9907bdb17c53e1a6 232 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 18 33 8.8E-8 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LH59_27815 428e77de49ca501bd4a6af9d01a458d1 286 SUPERFAMILY SSF51215 21 154 2.35E-16 T 14-10-2018 IPR037923 Transcription regulator HTH-like LH59_27815 428e77de49ca501bd4a6af9d01a458d1 286 Pfam PF12833 Helix-turn-helix domain 200 277 2.8E-20 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_27815 428e77de49ca501bd4a6af9d01a458d1 286 Pfam PF02311 AraC-like ligand binding domain 32 153 8.9E-17 T 14-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 LH59_27815 428e77de49ca501bd4a6af9d01a458d1 286 SUPERFAMILY SSF46689 179 228 3.88E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_27815 428e77de49ca501bd4a6af9d01a458d1 286 SMART SM00342 194 276 3.5E-26 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_27815 428e77de49ca501bd4a6af9d01a458d1 286 Gene3D G3DSA:1.10.10.60 237 282 2.9E-9 T 14-10-2018 LH59_27815 428e77de49ca501bd4a6af9d01a458d1 286 SUPERFAMILY SSF46689 230 280 9.86E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_27815 428e77de49ca501bd4a6af9d01a458d1 286 Gene3D G3DSA:1.10.10.60 176 236 2.7E-16 T 14-10-2018 LH59_00920 49ba892ad3338f40b483f00bd12539e7 75 Pfam PF02416 mttA/Hcf106 family 5 49 3.2E-13 T 14-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 LH59_00920 49ba892ad3338f40b483f00bd12539e7 75 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 74 22.469 T 14-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 LH59_00920 49ba892ad3338f40b483f00bd12539e7 75 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 3 46 3.6E-23 T 14-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 LH59_03760 6f912043066505ba08c38310b7ecff0d 299 SUPERFAMILY SSF103481 34 135 1.44E-12 T 14-10-2018 LH59_03760 6f912043066505ba08c38310b7ecff0d 299 SUPERFAMILY SSF103481 194 286 7.98E-10 T 14-10-2018 LH59_03760 6f912043066505ba08c38310b7ecff0d 299 Pfam PF00892 EamA-like transporter family 2 133 2.8E-18 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_03760 6f912043066505ba08c38310b7ecff0d 299 Pfam PF00892 EamA-like transporter family 148 284 4.7E-20 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_06595 405420efb5c7e4e95eddf7e335ebfe74 305 Pfam PF00248 Aldo/keto reductase family 47 287 1.8E-31 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain LH59_06595 405420efb5c7e4e95eddf7e335ebfe74 305 SUPERFAMILY SSF51430 32 289 8.25E-50 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily LH59_06595 405420efb5c7e4e95eddf7e335ebfe74 305 Gene3D G3DSA:3.20.20.100 25 288 8.2E-45 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily LH59_11910 1e4bdac8b9c26caff681c4dc1c6ed5aa 400 SUPERFAMILY SSF103473 4 376 1.44E-52 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_11910 1e4bdac8b9c26caff681c4dc1c6ed5aa 400 Gene3D G3DSA:1.20.1250.20 195 376 1.1E-13 T 14-10-2018 LH59_11910 1e4bdac8b9c26caff681c4dc1c6ed5aa 400 Gene3D G3DSA:1.20.1250.20 3 190 4.0E-29 T 14-10-2018 LH59_11910 1e4bdac8b9c26caff681c4dc1c6ed5aa 400 Pfam PF07690 Major Facilitator Superfamily 9 339 1.6E-39 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_10905 9d5c1d6140ca9681b0b9ae9ed0127f58 260 SUPERFAMILY SSF56219 1 258 5.76E-80 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily LH59_10905 9d5c1d6140ca9681b0b9ae9ed0127f58 260 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 250 1.1E-21 T 14-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase LH59_10905 9d5c1d6140ca9681b0b9ae9ed0127f58 260 ProSitePatterns PS00728 AP endonucleases family 1 signature 3. 214 225 - T 14-10-2018 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 Reactome: R-HSA-110357|Reactome: R-HSA-110362|Reactome: R-HSA-110373|Reactome: R-HSA-5651801|Reactome: R-HSA-73930|Reactome: R-HSA-73933 LH59_10905 9d5c1d6140ca9681b0b9ae9ed0127f58 260 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 257 3.2E-77 T 14-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 LH59_10905 9d5c1d6140ca9681b0b9ae9ed0127f58 260 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 257 4.8E-79 T 14-10-2018 LH59_10905 9d5c1d6140ca9681b0b9ae9ed0127f58 260 Gene3D G3DSA:3.60.10.10 1 258 9.2E-76 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily LH59_12325 8da4478d48c02856c84899f728204280 124 Gene3D G3DSA:3.40.30.10 1 123 2.7E-29 T 14-10-2018 LH59_12325 8da4478d48c02856c84899f728204280 124 SUPERFAMILY SSF52833 2 105 4.37E-32 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_12325 8da4478d48c02856c84899f728204280 124 Pfam PF00085 Thioredoxin 3 100 2.1E-25 T 14-10-2018 IPR013766 Thioredoxin domain GO:0045454 LH59_12325 8da4478d48c02856c84899f728204280 124 ProSitePatterns PS00194 Thioredoxin family active site. 22 40 - T 14-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 LH59_12325 8da4478d48c02856c84899f728204280 124 PRINTS PR00421 Thioredoxin family signature 68 79 4.7E-9 T 14-10-2018 LH59_12325 8da4478d48c02856c84899f728204280 124 PRINTS PR00421 Thioredoxin family signature 29 38 4.7E-9 T 14-10-2018 LH59_12325 8da4478d48c02856c84899f728204280 124 PRINTS PR00421 Thioredoxin family signature 21 29 4.7E-9 T 14-10-2018 LH59_12325 8da4478d48c02856c84899f728204280 124 PIRSF PIRSF000077 1 104 2.9E-27 T 14-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 LH59_17755 90cb4c57891dbbbcd5cb2d8763e99825 216 SUPERFAMILY SSF101386 5 214 9.16E-50 T 14-10-2018 LH59_17755 90cb4c57891dbbbcd5cb2d8763e99825 216 Pfam PF08761 dUTPase 8 169 3.0E-24 T 14-10-2018 IPR014871 dUTPase/dCTP pyrophosphatase KEGG: 00240+3.6.1.12 LH59_17755 90cb4c57891dbbbcd5cb2d8763e99825 216 Gene3D G3DSA:1.10.4010.10 1 216 2.3E-59 T 14-10-2018 LH59_20825 357ec46e65d15b4e448684ede64a2a89 423 Gene3D G3DSA:1.20.1250.20 4 411 8.5E-42 T 14-10-2018 LH59_20825 357ec46e65d15b4e448684ede64a2a89 423 SUPERFAMILY SSF103473 9 410 2.75E-50 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_20825 357ec46e65d15b4e448684ede64a2a89 423 Pfam PF07690 Major Facilitator Superfamily 23 317 8.5E-26 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_08240 374945acd3712c6ca445862a94370983 230 Gene3D G3DSA:1.20.950.20 1 169 6.7E-18 T 14-10-2018 LH59_08240 374945acd3712c6ca445862a94370983 230 Pfam PF01292 Prokaryotic cytochrome b561 11 180 4.5E-21 T 14-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 LH59_08240 374945acd3712c6ca445862a94370983 230 SUPERFAMILY SSF81342 7 189 9.42E-35 T 14-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 LH59_18150 8642b27fc82c9d0d233955394745f757 322 Gene3D G3DSA:3.40.190.290 98 304 3.3E-32 T 14-10-2018 LH59_18150 8642b27fc82c9d0d233955394745f757 322 SUPERFAMILY SSF46785 7 87 1.76E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_18150 8642b27fc82c9d0d233955394745f757 322 Pfam PF03466 LysR substrate binding domain 95 302 3.3E-32 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_18150 8642b27fc82c9d0d233955394745f757 322 Gene3D G3DSA:1.10.10.10 8 97 7.2E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_18150 8642b27fc82c9d0d233955394745f757 322 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 69 5.3E-16 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_18150 8642b27fc82c9d0d233955394745f757 322 SUPERFAMILY SSF53850 97 306 2.86E-33 T 14-10-2018 LH59_12535 5a93d48af97141647d0f4f79f24bfe09 283 Pfam PF02653 Branched-chain amino acid transport system / permease component 6 272 4.8E-43 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_04050 4e61c41a41977ba9b61104aaffef4769 468 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 7 463 4.9E-166 T 14-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 LH59_04050 4e61c41a41977ba9b61104aaffef4769 468 SUPERFAMILY SSF51984 6 92 3.53E-29 T 14-10-2018 LH59_04050 4e61c41a41977ba9b61104aaffef4769 468 Pfam PF08245 Mur ligase middle domain 110 294 2.3E-26 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 LH59_04050 4e61c41a41977ba9b61104aaffef4769 468 Pfam PF02875 Mur ligase family, glutamate ligase domain 316 405 2.1E-19 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 LH59_04050 4e61c41a41977ba9b61104aaffef4769 468 SUPERFAMILY SSF53623 91 312 3.01E-69 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 LH59_04050 4e61c41a41977ba9b61104aaffef4769 468 Gene3D G3DSA:3.40.1190.10 94 311 1.6E-76 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 LH59_04050 4e61c41a41977ba9b61104aaffef4769 468 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 5 468 42.385 T 14-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 LH59_04050 4e61c41a41977ba9b61104aaffef4769 468 Pfam PF01225 Mur ligase family, catalytic domain 7 105 1.7E-26 T 14-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 LH59_04050 4e61c41a41977ba9b61104aaffef4769 468 Gene3D G3DSA:3.90.190.20 312 466 9.9E-44 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 LH59_04050 4e61c41a41977ba9b61104aaffef4769 468 Gene3D G3DSA:3.40.50.720 6 92 6.7E-31 T 14-10-2018 LH59_04050 4e61c41a41977ba9b61104aaffef4769 468 SUPERFAMILY SSF53244 313 460 1.1E-45 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 LH59_05955 00606cdf28736047ad9e722837baf5dd 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 312 5.5E-38 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_05955 00606cdf28736047ad9e722837baf5dd 314 SUPERFAMILY SSF161098 89 298 4.25E-17 T 14-10-2018 IPR035906 MetI-like superfamily LH59_05955 00606cdf28736047ad9e722837baf5dd 314 Gene3D G3DSA:1.10.3720.10 85 304 2.3E-22 T 14-10-2018 IPR035906 MetI-like superfamily LH59_07415 463974dc59c677dba41d3d6791cb40d2 248 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 36 209 3.4E-40 T 14-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 LH59_07415 463974dc59c677dba41d3d6791cb40d2 248 Gene3D G3DSA:3.40.50.620 10 244 4.0E-68 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LH59_07415 463974dc59c677dba41d3d6791cb40d2 248 SUPERFAMILY SSF52402 15 197 1.18E-46 T 14-10-2018 LH59_07415 463974dc59c677dba41d3d6791cb40d2 248 TIGRFAM TIGR02055 APS_reductase: adenylylsulfate reductase, thioredoxin dependent 40 233 5.9E-82 T 14-10-2018 IPR011798 Adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019344|GO:0055114 KEGG: 00920+1.8.4.8 LH59_07415 463974dc59c677dba41d3d6791cb40d2 248 PIRSF PIRSF000857 5 239 2.5E-78 T 14-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 LH59_26650 732def65cf68603e5a545507680addf8 308 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 3 301 8.8E-99 T 14-10-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 LH59_26650 732def65cf68603e5a545507680addf8 308 Pfam PF02603 HPr Serine kinase N terminus 3 127 2.3E-23 T 14-10-2018 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 LH59_26650 732def65cf68603e5a545507680addf8 308 SUPERFAMILY SSF53795 132 298 1.95E-35 T 14-10-2018 LH59_26650 732def65cf68603e5a545507680addf8 308 Gene3D G3DSA:3.40.50.300 130 308 6.6E-65 T 14-10-2018 LH59_26650 732def65cf68603e5a545507680addf8 308 Gene3D G3DSA:3.40.1390.20 1 129 1.9E-23 T 14-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily LH59_26650 732def65cf68603e5a545507680addf8 308 SUPERFAMILY SSF75138 7 131 1.7E-29 T 14-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily LH59_26650 732def65cf68603e5a545507680addf8 308 Pfam PF07475 HPr Serine kinase C-terminal domain 129 299 1.5E-64 T 14-10-2018 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 LH59_26650 732def65cf68603e5a545507680addf8 308 Hamap MF_01249 HPr kinase/phosphorylase [hprK]. 1 306 37.481 T 14-10-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 LH59_04870 f9fe53c460a71524a5af7f00970c69d6 325 SUPERFAMILY SSF54292 218 323 4.06E-25 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 LH59_04870 f9fe53c460a71524a5af7f00970c69d6 325 SUPERFAMILY SSF52343 102 233 2.1E-28 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain LH59_04870 f9fe53c460a71524a5af7f00970c69d6 325 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 274 282 - T 14-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 LH59_04870 f9fe53c460a71524a5af7f00970c69d6 325 Pfam PF00175 Oxidoreductase NAD-binding domain 120 209 3.5E-7 T 14-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 LH59_04870 f9fe53c460a71524a5af7f00970c69d6 325 Gene3D G3DSA:2.40.30.10 1 105 2.3E-21 T 14-10-2018 LH59_04870 f9fe53c460a71524a5af7f00970c69d6 325 Gene3D G3DSA:3.10.20.30 230 325 2.4E-24 T 14-10-2018 IPR012675 Beta-grasp domain superfamily LH59_04870 f9fe53c460a71524a5af7f00970c69d6 325 SUPERFAMILY SSF63380 2 104 5.38E-18 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel LH59_04870 f9fe53c460a71524a5af7f00970c69d6 325 Gene3D G3DSA:3.40.50.80 112 228 2.0E-27 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain LH59_04870 f9fe53c460a71524a5af7f00970c69d6 325 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 247 316 8.6E-8 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 LH59_04870 f9fe53c460a71524a5af7f00970c69d6 325 PRINTS PR00409 Phthalate dioxygenase reductase family signature 144 153 3.5E-10 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 LH59_04870 f9fe53c460a71524a5af7f00970c69d6 325 PRINTS PR00409 Phthalate dioxygenase reductase family signature 51 65 3.5E-10 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 LH59_04870 f9fe53c460a71524a5af7f00970c69d6 325 PRINTS PR00409 Phthalate dioxygenase reductase family signature 196 204 3.5E-10 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 LH59_04870 f9fe53c460a71524a5af7f00970c69d6 325 PRINTS PR00409 Phthalate dioxygenase reductase family signature 28 38 3.5E-10 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 LH59_05820 bf869b21ede2f7661a3067fccf2ba41d 251 SUPERFAMILY SSF161098 48 229 1.2E-23 T 14-10-2018 IPR035906 MetI-like superfamily LH59_05820 bf869b21ede2f7661a3067fccf2ba41d 251 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 72 245 3.7E-20 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_05820 bf869b21ede2f7661a3067fccf2ba41d 251 Gene3D G3DSA:1.10.3720.10 48 237 2.0E-22 T 14-10-2018 IPR035906 MetI-like superfamily LH59_04530 8c061dc871595cc157443e531f0cd17f 297 Pfam PF03466 LysR substrate binding domain 89 293 7.3E-46 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_04530 8c061dc871595cc157443e531f0cd17f 297 Gene3D G3DSA:3.40.190.290 93 296 1.2E-44 T 14-10-2018 LH59_04530 8c061dc871595cc157443e531f0cd17f 297 Gene3D G3DSA:1.10.10.10 3 91 8.6E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_04530 8c061dc871595cc157443e531f0cd17f 297 SUPERFAMILY SSF46785 1 113 2.63E-27 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_04530 8c061dc871595cc157443e531f0cd17f 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 3.6E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_04530 8c061dc871595cc157443e531f0cd17f 297 SUPERFAMILY SSF53850 90 296 1.02E-45 T 14-10-2018 LH59_10945 52764483953d64a8693f984514399c18 194 Gene3D G3DSA:3.40.630.30 5 169 2.1E-50 T 14-10-2018 LH59_10945 52764483953d64a8693f984514399c18 194 Pfam PF13302 Acetyltransferase (GNAT) domain 8 142 5.8E-22 T 14-10-2018 IPR000182 GNAT domain LH59_10945 52764483953d64a8693f984514399c18 194 SUPERFAMILY SSF55729 6 166 1.74E-43 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_01975 2170970145f862dac101164dde22d50f 593 SUPERFAMILY SSF50156 511 581 8.02E-12 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 LH59_01975 2170970145f862dac101164dde22d50f 593 SUPERFAMILY SSF55486 247 439 7.1E-8 T 14-10-2018 LH59_01975 2170970145f862dac101164dde22d50f 593 Gene3D G3DSA:2.60.40.3650 10 187 1.0E-60 T 14-10-2018 LH59_01975 2170970145f862dac101164dde22d50f 593 PIRSF PIRSF016493 7 593 1.5E-209 T 14-10-2018 IPR024191 Peptidase M61 LH59_01975 2170970145f862dac101164dde22d50f 593 Gene3D G3DSA:1.10.390.60 189 477 2.4E-104 T 14-10-2018 LH59_01975 2170970145f862dac101164dde22d50f 593 Pfam PF13180 PDZ domain 505 580 1.0E-8 T 14-10-2018 IPR001478 PDZ domain GO:0005515 LH59_01975 2170970145f862dac101164dde22d50f 593 SMART SM00228 501 571 5.6E-4 T 14-10-2018 IPR001478 PDZ domain GO:0005515 LH59_01975 2170970145f862dac101164dde22d50f 593 Gene3D G3DSA:2.30.42.10 502 591 2.1E-15 T 14-10-2018 LH59_01975 2170970145f862dac101164dde22d50f 593 Pfam PF05299 M61 glycyl aminopeptidase 291 407 2.4E-48 T 14-10-2018 IPR007963 Peptidase M61, catalytic domain LH59_01980 ae942f5fd43acc87adb9621979d0451e 258 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 257 6.8E-82 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 LH59_01980 ae942f5fd43acc87adb9621979d0451e 258 Gene3D G3DSA:3.90.226.10 3 199 1.3E-74 T 14-10-2018 LH59_01980 ae942f5fd43acc87adb9621979d0451e 258 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 99 119 - T 14-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 LH59_01980 ae942f5fd43acc87adb9621979d0451e 258 Gene3D G3DSA:1.10.12.10 201 257 9.8E-28 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal LH59_01980 ae942f5fd43acc87adb9621979d0451e 258 SUPERFAMILY SSF52096 1 258 2.64E-92 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily LH59_25865 6086ab6032606db48c60bea0168121fa 465 Gene3D G3DSA:3.50.50.60 6 327 5.2E-104 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_25865 6086ab6032606db48c60bea0168121fa 465 PIRSF PIRSF000350 1 463 2.0E-67 T 14-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 LH59_25865 6086ab6032606db48c60bea0168121fa 465 Gene3D G3DSA:3.30.390.30 342 465 1.6E-39 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 LH59_25865 6086ab6032606db48c60bea0168121fa 465 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 6 464 1.2E-150 T 14-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 LH59_25865 6086ab6032606db48c60bea0168121fa 465 SUPERFAMILY SSF51905 2 331 2.96E-60 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_25865 6086ab6032606db48c60bea0168121fa 465 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 342 454 1.0E-32 T 14-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 LH59_25865 6086ab6032606db48c60bea0168121fa 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 134 152 1.4E-35 T 14-10-2018 LH59_25865 6086ab6032606db48c60bea0168121fa 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 275 1.4E-35 T 14-10-2018 LH59_25865 6086ab6032606db48c60bea0168121fa 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 287 309 1.4E-35 T 14-10-2018 LH59_25865 6086ab6032606db48c60bea0168121fa 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 172 190 1.4E-35 T 14-10-2018 LH59_25865 6086ab6032606db48c60bea0168121fa 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 1.4E-35 T 14-10-2018 LH59_25865 6086ab6032606db48c60bea0168121fa 465 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 322 1.6E-60 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LH59_25865 6086ab6032606db48c60bea0168121fa 465 Gene3D G3DSA:3.50.50.60 146 266 5.2E-104 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_25865 6086ab6032606db48c60bea0168121fa 465 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 40 50 - T 14-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 LH59_25865 6086ab6032606db48c60bea0168121fa 465 SUPERFAMILY SSF55424 342 464 1.89E-36 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 LH59_25865 6086ab6032606db48c60bea0168121fa 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 338 359 2.9E-66 T 14-10-2018 LH59_25865 6086ab6032606db48c60bea0168121fa 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 407 422 2.9E-66 T 14-10-2018 LH59_25865 6086ab6032606db48c60bea0168121fa 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 137 146 2.9E-66 T 14-10-2018 LH59_25865 6086ab6032606db48c60bea0168121fa 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 2.9E-66 T 14-10-2018 LH59_25865 6086ab6032606db48c60bea0168121fa 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 260 274 2.9E-66 T 14-10-2018 LH59_25865 6086ab6032606db48c60bea0168121fa 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 429 449 2.9E-66 T 14-10-2018 LH59_25865 6086ab6032606db48c60bea0168121fa 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 172 197 2.9E-66 T 14-10-2018 LH59_25865 6086ab6032606db48c60bea0168121fa 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 2.9E-66 T 14-10-2018 LH59_25865 6086ab6032606db48c60bea0168121fa 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 302 309 2.9E-66 T 14-10-2018 LH59_03270 320c900c59d7146710239f889d317b5b 283 SUPERFAMILY SSF53474 43 280 1.41E-28 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_03270 320c900c59d7146710239f889d317b5b 283 Pfam PF12697 Alpha/beta hydrolase family 50 262 4.0E-17 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_03270 320c900c59d7146710239f889d317b5b 283 Gene3D G3DSA:3.40.50.1820 40 277 6.0E-28 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_04390 ae04d823374fcee87a941d606b5b20ff 480 ProSitePatterns PS00110 Pyruvate kinase active site signature. 217 229 - T 14-10-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 LH59_04390 ae04d823374fcee87a941d606b5b20ff 480 PRINTS PR01050 Pyruvate kinase family signature 274 298 2.7E-50 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 LH59_04390 ae04d823374fcee87a941d606b5b20ff 480 PRINTS PR01050 Pyruvate kinase family signature 189 203 2.7E-50 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 LH59_04390 ae04d823374fcee87a941d606b5b20ff 480 PRINTS PR01050 Pyruvate kinase family signature 62 78 2.7E-50 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 LH59_04390 ae04d823374fcee87a941d606b5b20ff 480 PRINTS PR01050 Pyruvate kinase family signature 222 248 2.7E-50 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 LH59_04390 ae04d823374fcee87a941d606b5b20ff 480 PRINTS PR01050 Pyruvate kinase family signature 249 273 2.7E-50 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 LH59_04390 ae04d823374fcee87a941d606b5b20ff 480 PRINTS PR01050 Pyruvate kinase family signature 318 334 2.7E-50 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 LH59_04390 ae04d823374fcee87a941d606b5b20ff 480 PRINTS PR01050 Pyruvate kinase family signature 299 317 2.7E-50 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 LH59_04390 ae04d823374fcee87a941d606b5b20ff 480 Gene3D G3DSA:3.20.20.60 5 340 6.1E-158 T 14-10-2018 LH59_04390 ae04d823374fcee87a941d606b5b20ff 480 SUPERFAMILY SSF50800 73 168 2.09E-23 T 14-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily LH59_04390 ae04d823374fcee87a941d606b5b20ff 480 Gene3D G3DSA:3.40.1380.20 341 475 6.1E-158 T 14-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 LH59_04390 ae04d823374fcee87a941d606b5b20ff 480 Pfam PF00224 Pyruvate kinase, barrel domain 5 343 6.3E-120 T 14-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 LH59_04390 ae04d823374fcee87a941d606b5b20ff 480 SUPERFAMILY SSF52935 328 479 6.28E-36 T 14-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 LH59_04390 ae04d823374fcee87a941d606b5b20ff 480 Pfam PF02887 Pyruvate kinase, alpha/beta domain 362 477 1.5E-25 T 14-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 LH59_04390 ae04d823374fcee87a941d606b5b20ff 480 Gene3D G3DSA:2.40.33.10 73 171 6.1E-158 T 14-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 LH59_04390 ae04d823374fcee87a941d606b5b20ff 480 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 5 477 2.0E-157 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 LH59_04390 ae04d823374fcee87a941d606b5b20ff 480 SUPERFAMILY SSF51621 3 345 1.69E-90 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 LH59_27085 2b573ee8f5720ce1b04ca08ba25fa9e1 473 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 5 469 7.4E-190 T 14-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 LH59_27085 2b573ee8f5720ce1b04ca08ba25fa9e1 473 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 2 470 52.182 T 14-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 LH59_27085 2b573ee8f5720ce1b04ca08ba25fa9e1 473 ProSitePatterns PS01244 Aconitase family signature 2. 403 416 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 LH59_27085 2b573ee8f5720ce1b04ca08ba25fa9e1 473 Gene3D G3DSA:3.30.499.10 331 472 5.7E-50 T 14-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 LH59_27085 2b573ee8f5720ce1b04ca08ba25fa9e1 473 Pfam PF00330 Aconitase family (aconitate hydratase) 9 461 5.9E-141 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 LH59_27085 2b573ee8f5720ce1b04ca08ba25fa9e1 473 Gene3D G3DSA:3.30.499.20 5 290 3.1E-87 T 14-10-2018 LH59_27085 2b573ee8f5720ce1b04ca08ba25fa9e1 473 ProSitePatterns PS00450 Aconitase family signature 1. 343 359 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 LH59_27085 2b573ee8f5720ce1b04ca08ba25fa9e1 473 PRINTS PR00415 Aconitase family signature 112 120 5.6E-41 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 LH59_27085 2b573ee8f5720ce1b04ca08ba25fa9e1 473 PRINTS PR00415 Aconitase family signature 403 416 5.6E-41 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 LH59_27085 2b573ee8f5720ce1b04ca08ba25fa9e1 473 PRINTS PR00415 Aconitase family signature 199 212 5.6E-41 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 LH59_27085 2b573ee8f5720ce1b04ca08ba25fa9e1 473 PRINTS PR00415 Aconitase family signature 137 152 5.6E-41 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 LH59_27085 2b573ee8f5720ce1b04ca08ba25fa9e1 473 PRINTS PR00415 Aconitase family signature 290 304 5.6E-41 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 LH59_27085 2b573ee8f5720ce1b04ca08ba25fa9e1 473 PRINTS PR00415 Aconitase family signature 347 358 5.6E-41 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 LH59_27085 2b573ee8f5720ce1b04ca08ba25fa9e1 473 PRINTS PR00415 Aconitase family signature 213 226 5.6E-41 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 LH59_27085 2b573ee8f5720ce1b04ca08ba25fa9e1 473 PRINTS PR00415 Aconitase family signature 123 136 5.6E-41 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 LH59_27085 2b573ee8f5720ce1b04ca08ba25fa9e1 473 SUPERFAMILY SSF53732 3 470 9.42E-154 T 14-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 LH59_02790 3a4b99fb727b187a3b184163d80870dc 250 Hamap MF_01092 Cell division protein ZapD [zapD]. 1 248 32.041 T 14-10-2018 IPR009777 Cell division protein ZapD LH59_02790 3a4b99fb727b187a3b184163d80870dc 250 Gene3D G3DSA:2.60.440.10 3 248 6.7E-81 T 14-10-2018 IPR027462 Z ring-associated protein D, C-terminal LH59_02790 3a4b99fb727b187a3b184163d80870dc 250 Gene3D G3DSA:1.10.3900.10 10 176 6.7E-81 T 14-10-2018 LH59_02790 3a4b99fb727b187a3b184163d80870dc 250 Pfam PF07072 Cell division protein 16 224 7.7E-76 T 14-10-2018 IPR009777 Cell division protein ZapD LH59_02790 3a4b99fb727b187a3b184163d80870dc 250 SUPERFAMILY SSF160950 2 248 6.67E-85 T 14-10-2018 IPR036268 ZapD domain superfamily LH59_03750 08d9da3b80ddc60ca80b2f6359638d91 154 SUPERFAMILY SSF52402 2 148 2.09E-35 T 14-10-2018 LH59_03750 08d9da3b80ddc60ca80b2f6359638d91 154 Gene3D G3DSA:3.40.50.620 1 149 9.5E-37 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LH59_03750 08d9da3b80ddc60ca80b2f6359638d91 154 Pfam PF00582 Universal stress protein family 1 148 1.5E-30 T 14-10-2018 IPR006016 UspA LH59_03750 08d9da3b80ddc60ca80b2f6359638d91 154 PRINTS PR01438 Universal stress protein signature 108 120 4.6E-18 T 14-10-2018 IPR006015 Universal stress protein A LH59_03750 08d9da3b80ddc60ca80b2f6359638d91 154 PRINTS PR01438 Universal stress protein signature 2 20 4.6E-18 T 14-10-2018 IPR006015 Universal stress protein A LH59_03750 08d9da3b80ddc60ca80b2f6359638d91 154 PRINTS PR01438 Universal stress protein signature 126 148 4.6E-18 T 14-10-2018 IPR006015 Universal stress protein A LH59_06205 9a5076595f468b44bbfa9266b8bd4ac1 694 Gene3D G3DSA:3.40.250.10 562 690 5.8E-9 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily LH59_06205 9a5076595f468b44bbfa9266b8bd4ac1 694 SUPERFAMILY SSF52821 570 687 1.96E-11 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily LH59_06205 9a5076595f468b44bbfa9266b8bd4ac1 694 SMART SM00450 576 685 0.0071 T 14-10-2018 IPR001763 Rhodanese-like domain LH59_06205 9a5076595f468b44bbfa9266b8bd4ac1 694 Pfam PF14247 Putative metallopeptidase 250 392 2.9E-27 T 14-10-2018 IPR025644 Putative metallopeptidase LH59_06205 9a5076595f468b44bbfa9266b8bd4ac1 694 Pfam PF14247 Putative metallopeptidase 437 491 1.9E-11 T 14-10-2018 IPR025644 Putative metallopeptidase LH59_06205 9a5076595f468b44bbfa9266b8bd4ac1 694 Pfam PF00581 Rhodanese-like domain 576 681 1.8E-4 T 14-10-2018 IPR001763 Rhodanese-like domain LH59_15505 ed153bb527e3a6071abbe03cce2eae4d 766 Pfam PF09994 Uncharacterized alpha/beta hydrolase domain (DUF2235) 314 431 2.6E-7 T 14-10-2018 IPR018712 Domain of unknown function DUF2235 LH59_19615 fe1d02b7837ba76133467eae38e9118c 355 PIRSF PIRSF000112 1 339 1.8E-64 T 14-10-2018 IPR016205 Glycerol dehydrogenase GO:0016614|GO:0046872|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 LH59_19615 fe1d02b7837ba76133467eae38e9118c 355 Pfam PF00465 Iron-containing alcohol dehydrogenase 8 345 8.9E-50 T 14-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 LH59_19615 fe1d02b7837ba76133467eae38e9118c 355 Gene3D G3DSA:1.20.1090.10 160 354 1.4E-52 T 14-10-2018 LH59_19615 fe1d02b7837ba76133467eae38e9118c 355 Gene3D G3DSA:3.40.50.1970 2 159 5.1E-35 T 14-10-2018 LH59_19615 fe1d02b7837ba76133467eae38e9118c 355 SUPERFAMILY SSF56796 2 353 3.01E-70 T 14-10-2018 LH59_15710 e9a316a6c31614d0337d38694edef4f1 176 Gene3D G3DSA:1.10.150.120 86 170 7.8E-25 T 14-10-2018 LH59_15710 e9a316a6c31614d0337d38694edef4f1 176 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 50 58 - T 14-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 LH59_15710 e9a316a6c31614d0337d38694edef4f1 176 Gene3D G3DSA:3.10.20.30 10 85 1.6E-26 T 14-10-2018 IPR012675 Beta-grasp domain superfamily LH59_15710 e9a316a6c31614d0337d38694edef4f1 176 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 17 72 3.1E-5 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 LH59_15710 e9a316a6c31614d0337d38694edef4f1 176 SUPERFAMILY SSF54292 14 89 3.54E-22 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 LH59_15710 e9a316a6c31614d0337d38694edef4f1 176 SUPERFAMILY SSF47741 95 163 8.5E-25 T 14-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily LH59_15710 e9a316a6c31614d0337d38694edef4f1 176 Pfam PF01799 [2Fe-2S] binding domain 84 156 9.1E-23 T 14-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 LH59_28005 cedf9fc447e24a1f8f74bfa1dcb8066e 126 Hamap MF_00422 Protein translocase subunit SecE [secE]. 65 121 11.537 T 14-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 LH59_28005 cedf9fc447e24a1f8f74bfa1dcb8066e 126 Gene3D G3DSA:1.20.5.1030 65 122 2.9E-15 T 14-10-2018 IPR038379 SecE superfamily LH59_28005 cedf9fc447e24a1f8f74bfa1dcb8066e 126 PRINTS PR01650 Bacterial translocase SecE signature 43 64 4.9E-8 T 14-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 LH59_28005 cedf9fc447e24a1f8f74bfa1dcb8066e 126 PRINTS PR01650 Bacterial translocase SecE signature 64 84 4.9E-8 T 14-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 LH59_28005 cedf9fc447e24a1f8f74bfa1dcb8066e 126 PRINTS PR01650 Bacterial translocase SecE signature 88 108 4.9E-8 T 14-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 LH59_28005 cedf9fc447e24a1f8f74bfa1dcb8066e 126 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 69 119 2.7E-19 T 14-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 LH59_28005 cedf9fc447e24a1f8f74bfa1dcb8066e 126 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 69 118 1.6E-17 T 14-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 LH59_02055 bfdf19215bf3b943199fbef771cc226b 275 Pfam PF02311 AraC-like ligand binding domain 15 147 1.6E-17 T 14-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 LH59_02055 bfdf19215bf3b943199fbef771cc226b 275 SUPERFAMILY SSF51215 25 154 5.23E-18 T 14-10-2018 IPR037923 Transcription regulator HTH-like LH59_02055 bfdf19215bf3b943199fbef771cc226b 275 SMART SM00342 189 272 1.9E-31 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_02055 bfdf19215bf3b943199fbef771cc226b 275 SUPERFAMILY SSF46689 225 273 5.38E-13 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_02055 bfdf19215bf3b943199fbef771cc226b 275 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 241 256 6.8E-7 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 LH59_02055 bfdf19215bf3b943199fbef771cc226b 275 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 256 272 6.8E-7 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 LH59_02055 bfdf19215bf3b943199fbef771cc226b 275 SUPERFAMILY SSF46689 176 223 4.93E-8 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_02055 bfdf19215bf3b943199fbef771cc226b 275 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 226 268 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 LH59_02055 bfdf19215bf3b943199fbef771cc226b 275 Gene3D G3DSA:1.10.10.60 174 275 1.2E-31 T 14-10-2018 LH59_02055 bfdf19215bf3b943199fbef771cc226b 275 Pfam PF12833 Helix-turn-helix domain 195 273 1.2E-24 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_16930 7fb19c7e52927ac85dcae1fada74d760 820 SMART SM00965 68 119 1.2E-9 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 LH59_16930 7fb19c7e52927ac85dcae1fada74d760 820 Pfam PF07715 TonB-dependent Receptor Plug Domain 164 266 1.0E-19 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_16930 7fb19c7e52927ac85dcae1fada74d760 820 SUPERFAMILY SSF56935 124 818 4.58E-123 T 14-10-2018 LH59_16930 7fb19c7e52927ac85dcae1fada74d760 820 Gene3D G3DSA:2.40.170.20 274 820 6.2E-165 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_16930 7fb19c7e52927ac85dcae1fada74d760 820 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 166 817 3.0E-110 T 14-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 LH59_16930 7fb19c7e52927ac85dcae1fada74d760 820 Pfam PF00593 TonB dependent receptor 356 817 5.4E-55 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_16930 7fb19c7e52927ac85dcae1fada74d760 820 Gene3D G3DSA:3.55.50.30 35 141 4.9E-26 T 14-10-2018 LH59_16930 7fb19c7e52927ac85dcae1fada74d760 820 Gene3D G3DSA:2.170.130.10 143 273 4.4E-34 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily LH59_16930 7fb19c7e52927ac85dcae1fada74d760 820 Pfam PF07660 Secretin and TonB N terminus short domain 69 104 6.5E-7 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 LH59_00435 33ab6437ff3a485b0b70192609ae5970 112 SUPERFAMILY SSF54593 7 111 8.06E-16 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_00435 33ab6437ff3a485b0b70192609ae5970 112 Gene3D G3DSA:3.10.180.10 6 112 1.8E-15 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_10050 f8ec6c278b9359a7040bc429b79dc32d 145 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 131 2.6E-26 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type LH59_10050 f8ec6c278b9359a7040bc429b79dc32d 145 Gene3D G3DSA:1.10.10.10 1 140 9.4E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_10050 f8ec6c278b9359a7040bc429b79dc32d 145 SUPERFAMILY SSF46785 2 133 1.11E-30 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_10050 f8ec6c278b9359a7040bc429b79dc32d 145 Pfam PF02082 Transcriptional regulator 1 83 3.8E-21 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type LH59_07410 a15487734f11d82210dbc83a17ae8802 354 Pfam PF12857 TOBE-like domain 288 345 5.2E-15 T 14-10-2018 IPR024765 TOBE-like domain KEGG: 00920+3.6.3.25 LH59_07410 a15487734f11d82210dbc83a17ae8802 354 TIGRFAM TIGR00968 3a0106s01: sulfate ABC transporter, ATP-binding protein 3 243 1.6E-120 T 14-10-2018 IPR005666 Sulphate transport system permease protein 1 GO:0008272|GO:0015419|GO:0016020|GO:0043190 KEGG: 00920+3.6.3.25 LH59_07410 a15487734f11d82210dbc83a17ae8802 354 Pfam PF00005 ABC transporter 18 164 6.0E-36 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_07410 a15487734f11d82210dbc83a17ae8802 354 SUPERFAMILY SSF52540 3 243 5.06E-87 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_07410 a15487734f11d82210dbc83a17ae8802 354 Gene3D G3DSA:3.40.50.300 2 281 7.1E-82 T 14-10-2018 LH59_07410 a15487734f11d82210dbc83a17ae8802 354 SMART SM00382 27 214 3.2E-19 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_07410 a15487734f11d82210dbc83a17ae8802 354 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_07410 a15487734f11d82210dbc83a17ae8802 354 SUPERFAMILY SSF50331 240 348 3.29E-5 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal LH59_16890 424d33abcc345d104418231cc88e9687 503 Pfam PF00515 Tetratricopeptide repeat 387 418 9.7E-7 T 14-10-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 LH59_16890 424d33abcc345d104418231cc88e9687 503 SUPERFAMILY SSF53300 93 245 1.63E-19 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily LH59_16890 424d33abcc345d104418231cc88e9687 503 SMART SM00327 92 260 3.5E-9 T 14-10-2018 IPR002035 von Willebrand factor, type A LH59_16890 424d33abcc345d104418231cc88e9687 503 SMART SM00028 386 419 3.8E-5 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 LH59_16890 424d33abcc345d104418231cc88e9687 503 SUPERFAMILY SSF48452 339 432 5.8E-11 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_16890 424d33abcc345d104418231cc88e9687 503 Pfam PF13519 von Willebrand factor type A domain 95 201 4.5E-15 T 14-10-2018 IPR002035 von Willebrand factor, type A LH59_16890 424d33abcc345d104418231cc88e9687 503 Gene3D G3DSA:3.40.50.410 92 264 4.1E-27 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily LH59_16890 424d33abcc345d104418231cc88e9687 503 Gene3D G3DSA:1.25.40.10 359 446 9.5E-13 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_27740 30ceb387c49b4e74599c0bd4e382695e 121 PIRSF PIRSF002134 1 121 6.4E-39 T 14-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27740 30ceb387c49b4e74599c0bd4e382695e 121 Pfam PF00416 Ribosomal protein S13/S18 3 108 1.6E-30 T 14-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27740 30ceb387c49b4e74599c0bd4e382695e 121 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 118 26.339 T 14-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27740 30ceb387c49b4e74599c0bd4e382695e 121 SUPERFAMILY SSF46946 2 114 2.94E-42 T 14-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 LH59_27740 30ceb387c49b4e74599c0bd4e382695e 121 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 14-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27740 30ceb387c49b4e74599c0bd4e382695e 121 Gene3D G3DSA:4.10.910.10 72 121 9.9E-24 T 14-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27740 30ceb387c49b4e74599c0bd4e382695e 121 Gene3D G3DSA:1.10.8.50 1 71 1.2E-25 T 14-10-2018 LH59_27740 30ceb387c49b4e74599c0bd4e382695e 121 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 2.0E-50 T 14-10-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_18265 920e826e061eb8d5b8080c798588e620 321 SMART SM00342 229 312 6.6E-24 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_18265 920e826e061eb8d5b8080c798588e620 321 SUPERFAMILY SSF46689 265 315 3.81E-8 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_18265 920e826e061eb8d5b8080c798588e620 321 Gene3D G3DSA:3.40.50.880 1 203 1.7E-63 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_18265 920e826e061eb8d5b8080c798588e620 321 Pfam PF01965 DJ-1/PfpI family 4 174 1.4E-22 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 LH59_18265 920e826e061eb8d5b8080c798588e620 321 Pfam PF12833 Helix-turn-helix domain 235 313 2.8E-19 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_18265 920e826e061eb8d5b8080c798588e620 321 SUPERFAMILY SSF46689 212 259 2.2E-8 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_18265 920e826e061eb8d5b8080c798588e620 321 Gene3D G3DSA:1.10.10.60 212 319 3.0E-24 T 14-10-2018 LH59_18265 920e826e061eb8d5b8080c798588e620 321 SUPERFAMILY SSF52317 3 195 3.7E-49 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_06935 a36577a53615420ed652c28b5fed0f89 895 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 14 873 0.0 T 14-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 LH59_06935 a36577a53615420ed652c28b5fed0f89 895 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 144 312 2.4E-8 T 14-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 LH59_06935 a36577a53615420ed652c28b5fed0f89 895 Gene3D G3DSA:3.40.50.920 720 889 2.5E-58 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 LH59_06935 a36577a53615420ed652c28b5fed0f89 895 Gene3D G3DSA:3.40.50.970 64 482 1.6E-124 T 14-10-2018 LH59_06935 a36577a53615420ed652c28b5fed0f89 895 SUPERFAMILY SSF52518 484 712 5.47E-93 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold LH59_06935 a36577a53615420ed652c28b5fed0f89 895 SUPERFAMILY SSF52922 717 875 6.12E-44 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 LH59_06935 a36577a53615420ed652c28b5fed0f89 895 SUPERFAMILY SSF52518 65 479 7.58E-125 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold LH59_06935 a36577a53615420ed652c28b5fed0f89 895 SMART SM00861 505 710 0.009 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain LH59_06935 a36577a53615420ed652c28b5fed0f89 895 TIGRFAM TIGR03186 AKGDH_not_PDH: alpha-ketoglutarate dehydrogenase 15 878 0.0 T 14-10-2018 IPR017600 Alpha-ketoglutarate dehydrogenase LH59_06935 a36577a53615420ed652c28b5fed0f89 895 Gene3D G3DSA:3.40.50.970 484 717 3.0E-102 T 14-10-2018 LH59_06935 a36577a53615420ed652c28b5fed0f89 895 PIRSF PIRSF000156 5 889 0.0 T 14-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 LH59_13900 0432ffaadabda600dffa1db23bd9f1ed 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 315 1.6E-37 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_13900 0432ffaadabda600dffa1db23bd9f1ed 318 SUPERFAMILY SSF161098 92 314 6.8E-23 T 14-10-2018 IPR035906 MetI-like superfamily LH59_13900 0432ffaadabda600dffa1db23bd9f1ed 318 Gene3D G3DSA:1.10.3720.10 88 310 6.1E-28 T 14-10-2018 IPR035906 MetI-like superfamily LH59_03565 0a02449b07b162f6345673bec1192086 132 SUPERFAMILY SSF82784 8 122 1.44E-27 T 14-10-2018 IPR036102 OsmC/Ohr superfamily LH59_03565 0a02449b07b162f6345673bec1192086 132 Gene3D G3DSA:3.30.300.20 2 129 3.7E-24 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta LH59_03565 0a02449b07b162f6345673bec1192086 132 Pfam PF02566 OsmC-like protein 32 124 6.6E-16 T 14-10-2018 IPR003718 OsmC/Ohr family LH59_14295 2d744392dffa08e674caea769d630440 279 Gene3D G3DSA:3.40.190.10 32 250 1.4E-42 T 14-10-2018 LH59_14295 2d744392dffa08e674caea769d630440 279 SUPERFAMILY SSF53850 36 258 1.44E-40 T 14-10-2018 LH59_14295 2d744392dffa08e674caea769d630440 279 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 41 252 1.2E-32 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_14295 2d744392dffa08e674caea769d630440 279 SMART SM00062 40 262 1.2E-28 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_14295 2d744392dffa08e674caea769d630440 279 Gene3D G3DSA:3.40.190.10 129 221 1.4E-42 T 14-10-2018 LH59_26965 48c7e0f0b89bbd6cf5fa30cbfbc9344a 220 Gene3D G3DSA:1.20.910.10 1 220 1.2E-65 T 14-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 LH59_26965 48c7e0f0b89bbd6cf5fa30cbfbc9344a 220 TIGRFAM TIGR04306 salvage_TenA: thiaminase II 18 214 4.2E-42 T 14-10-2018 IPR027574 Thiaminase II GO:0006772|GO:0050334 KEGG: 00730+3.5.99.2|MetaCyc: PWY-6899|MetaCyc: PWY-7356 LH59_26965 48c7e0f0b89bbd6cf5fa30cbfbc9344a 220 SUPERFAMILY SSF48613 1 213 8.16E-67 T 14-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 LH59_26965 48c7e0f0b89bbd6cf5fa30cbfbc9344a 220 Pfam PF03070 TENA/THI-4/PQQC family 22 214 1.8E-38 T 14-10-2018 IPR004305 Thiaminase-2/PQQC LH59_08990 7dbf18a6a339dda94682717016c51052 108 PRINTS PR00421 Thioredoxin family signature 24 32 8.8E-10 T 14-10-2018 LH59_08990 7dbf18a6a339dda94682717016c51052 108 PRINTS PR00421 Thioredoxin family signature 32 41 8.8E-10 T 14-10-2018 LH59_08990 7dbf18a6a339dda94682717016c51052 108 PRINTS PR00421 Thioredoxin family signature 72 83 8.8E-10 T 14-10-2018 LH59_08990 7dbf18a6a339dda94682717016c51052 108 SUPERFAMILY SSF52833 3 108 6.49E-41 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_08990 7dbf18a6a339dda94682717016c51052 108 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 105 5.0E-39 T 14-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 LH59_08990 7dbf18a6a339dda94682717016c51052 108 Pfam PF00085 Thioredoxin 5 105 1.5E-34 T 14-10-2018 IPR013766 Thioredoxin domain GO:0045454 LH59_08990 7dbf18a6a339dda94682717016c51052 108 PIRSF PIRSF000077 2 108 2.1E-44 T 14-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 LH59_08990 7dbf18a6a339dda94682717016c51052 108 Gene3D G3DSA:3.40.30.10 1 106 1.3E-36 T 14-10-2018 LH59_08990 7dbf18a6a339dda94682717016c51052 108 ProSitePatterns PS00194 Thioredoxin family active site. 25 43 - T 14-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 LH59_28040 854de14f97bf47a40ddf1fc8aaf1dba3 463 Gene3D G3DSA:3.40.309.10 234 426 3.4E-140 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 LH59_28040 854de14f97bf47a40ddf1fc8aaf1dba3 463 Pfam PF00171 Aldehyde dehydrogenase family 5 456 2.3E-127 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 LH59_28040 854de14f97bf47a40ddf1fc8aaf1dba3 463 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 230 237 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 LH59_28040 854de14f97bf47a40ddf1fc8aaf1dba3 463 SUPERFAMILY SSF53720 6 460 1.44E-131 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 LH59_28040 854de14f97bf47a40ddf1fc8aaf1dba3 463 Gene3D G3DSA:3.40.605.10 7 455 3.4E-140 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 LH59_16340 40625941c37fefc1a245d443a9afa909 293 Gene3D G3DSA:3.40.190.10 164 262 6.6E-36 T 14-10-2018 LH59_16340 40625941c37fefc1a245d443a9afa909 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.3E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_16340 40625941c37fefc1a245d443a9afa909 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.3E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_16340 40625941c37fefc1a245d443a9afa909 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.3E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_16340 40625941c37fefc1a245d443a9afa909 293 SUPERFAMILY SSF53850 87 288 1.58E-37 T 14-10-2018 LH59_16340 40625941c37fefc1a245d443a9afa909 293 Gene3D G3DSA:1.10.10.10 1 88 3.1E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_16340 40625941c37fefc1a245d443a9afa909 293 SUPERFAMILY SSF46785 1 108 1.54E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_16340 40625941c37fefc1a245d443a9afa909 293 Pfam PF03466 LysR substrate binding domain 86 283 4.2E-40 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_16340 40625941c37fefc1a245d443a9afa909 293 Gene3D G3DSA:3.40.190.10 89 273 6.6E-36 T 14-10-2018 LH59_16340 40625941c37fefc1a245d443a9afa909 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 60 5.1E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_03790 87aa5fd5de4ebeb2410b1bdf38a4fdad 230 Pfam PF13174 Tetratricopeptide repeat 184 216 6.0E-4 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 LH59_03790 87aa5fd5de4ebeb2410b1bdf38a4fdad 230 TIGRFAM TIGR02795 tol_pal_ybgF: tol-pal system protein YbgF 109 226 3.6E-32 T 14-10-2018 IPR014162 Cell division coordinator CpoB, C-terminal LH59_03790 87aa5fd5de4ebeb2410b1bdf38a4fdad 230 SUPERFAMILY SSF48452 111 228 1.79E-12 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_03790 87aa5fd5de4ebeb2410b1bdf38a4fdad 230 Gene3D G3DSA:1.25.40.10 109 230 5.6E-25 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_03790 87aa5fd5de4ebeb2410b1bdf38a4fdad 230 Pfam PF13432 Tetratricopeptide repeat 113 180 2.0E-10 T 14-10-2018 LH59_03790 87aa5fd5de4ebeb2410b1bdf38a4fdad 230 Hamap MF_02066 Cell division coordinator CpoB [cpoB]. 7 229 17.881 T 14-10-2018 IPR034706 Cell division coordinator CpoB GO:0051301 LH59_25410 bf06cb081b0dd8668935e215b79a1bf6 313 SUPERFAMILY SSF46785 4 111 1.49E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_25410 bf06cb081b0dd8668935e215b79a1bf6 313 SUPERFAMILY SSF53850 94 303 2.95E-40 T 14-10-2018 LH59_25410 bf06cb081b0dd8668935e215b79a1bf6 313 Gene3D G3DSA:3.40.190.10 95 287 2.1E-45 T 14-10-2018 LH59_25410 bf06cb081b0dd8668935e215b79a1bf6 313 Gene3D G3DSA:1.10.10.10 3 88 2.6E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_25410 bf06cb081b0dd8668935e215b79a1bf6 313 Gene3D G3DSA:3.40.190.10 168 273 2.1E-45 T 14-10-2018 LH59_25410 bf06cb081b0dd8668935e215b79a1bf6 313 Pfam PF03466 LysR substrate binding domain 93 298 1.5E-42 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_25410 bf06cb081b0dd8668935e215b79a1bf6 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 66 1.3E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_25410 bf06cb081b0dd8668935e215b79a1bf6 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 1.6E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_25410 bf06cb081b0dd8668935e215b79a1bf6 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 1.6E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_25410 bf06cb081b0dd8668935e215b79a1bf6 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 1.6E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_04770 259be61415d005746c95f99047396ac5 210 Gene3D G3DSA:3.30.470.10 1 76 4.8E-14 T 14-10-2018 LH59_04770 259be61415d005746c95f99047396ac5 210 Pfam PF01063 Amino-transferase class IV 5 206 4.3E-35 T 14-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 LH59_04770 259be61415d005746c95f99047396ac5 210 SUPERFAMILY SSF56752 4 206 4.32E-40 T 14-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 LH59_04770 259be61415d005746c95f99047396ac5 210 Gene3D G3DSA:3.20.10.10 82 209 1.3E-35 T 14-10-2018 LH59_17060 7ee3980428d16d50c39f32a42bd2797a 312 Gene3D G3DSA:3.30.70.2130 94 219 2.7E-5 T 14-10-2018 LH59_17060 7ee3980428d16d50c39f32a42bd2797a 312 PIRSF PIRSF015283 225 308 1.1E-5 T 14-10-2018 IPR016631 Regulatory, RpfE LH59_17060 7ee3980428d16d50c39f32a42bd2797a 312 PIRSF PIRSF015283 1 234 1.7E-73 T 14-10-2018 IPR016631 Regulatory, RpfE LH59_24945 f38cb7c48dc7a183e6c615c516e7e4d5 77 SUPERFAMILY SSF47413 1 68 1.24E-18 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 LH59_24945 f38cb7c48dc7a183e6c615c516e7e4d5 77 SMART SM00530 6 62 7.0E-7 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LH59_24945 f38cb7c48dc7a183e6c615c516e7e4d5 77 Gene3D G3DSA:1.10.260.40 4 66 3.3E-10 T 14-10-2018 LH59_24945 f38cb7c48dc7a183e6c615c516e7e4d5 77 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 6 67 3.7E-24 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LH59_07395 41e5062e7a37041cd2e0459497ba3649 342 Gene3D G3DSA:3.40.190.10 36 304 6.9E-135 T 14-10-2018 LH59_07395 41e5062e7a37041cd2e0459497ba3649 342 SUPERFAMILY SSF53850 29 338 7.94E-93 T 14-10-2018 LH59_07395 41e5062e7a37041cd2e0459497ba3649 342 ProSitePatterns PS00757 Prokaryotic sulfate-binding proteins signature 2. 154 162 - T 14-10-2018 IPR034408 Sulphate/thiosulphate-binding site GO:1901681 LH59_07395 41e5062e7a37041cd2e0459497ba3649 342 Gene3D G3DSA:3.40.190.10 123 335 6.9E-135 T 14-10-2018 LH59_07395 41e5062e7a37041cd2e0459497ba3649 342 TIGRFAM TIGR00971 3a0106s03: sulfate ABC transporter, sulfate-binding protein 29 336 3.5E-147 T 14-10-2018 IPR005669 Thiosulphate/Sulfate-binding protein GO:0008272|GO:0015419 LH59_07395 41e5062e7a37041cd2e0459497ba3649 342 Pfam PF13531 Bacterial extracellular solute-binding protein 39 289 2.7E-45 T 14-10-2018 LH59_02320 ce2dfabe9f4aa7ffa5f50d60be5ed9f8 523 Gene3D G3DSA:3.30.590.20 17 521 1.2E-185 T 14-10-2018 LH59_02320 ce2dfabe9f4aa7ffa5f50d60be5ed9f8 523 SUPERFAMILY SSF55931 8 511 7.19E-182 T 14-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 LH59_02320 ce2dfabe9f4aa7ffa5f50d60be5ed9f8 523 TIGRFAM TIGR01434 glu_cys_ligase: glutamate--cysteine ligase 7 514 3.9E-189 T 14-10-2018 IPR006334 Glutamate--cysteine ligase, monofunctional GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 LH59_02320 ce2dfabe9f4aa7ffa5f50d60be5ed9f8 523 Hamap MF_00578 Glutamate--cysteine ligase [gshA]. 1 523 210.592 T 14-10-2018 IPR006334 Glutamate--cysteine ligase, monofunctional GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 LH59_02320 ce2dfabe9f4aa7ffa5f50d60be5ed9f8 523 Pfam PF04262 Glutamate-cysteine ligase 14 376 5.3E-155 T 14-10-2018 IPR007370 Glutamate--cysteine ligase GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 LH59_12300 5faa77cb387dd985eb0dd49502d5dfe2 256 Pfam PF00005 ABC transporter 20 157 1.0E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_12300 5faa77cb387dd985eb0dd49502d5dfe2 256 SUPERFAMILY SSF52540 3 213 4.03E-66 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_12300 5faa77cb387dd985eb0dd49502d5dfe2 256 SMART SM00382 27 208 4.4E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_12300 5faa77cb387dd985eb0dd49502d5dfe2 256 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_12300 5faa77cb387dd985eb0dd49502d5dfe2 256 Gene3D G3DSA:3.40.50.300 1 241 4.2E-61 T 14-10-2018 LH59_19425 209912bbe19afb86ae869734a56e2f7b 868 SUPERFAMILY SSF50249 417 533 1.71E-27 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_19425 209912bbe19afb86ae869734a56e2f7b 868 Gene3D G3DSA:2.40.50.140 416 533 6.0E-36 T 14-10-2018 LH59_19425 209912bbe19afb86ae869734a56e2f7b 868 TIGRFAM TIGR02776 NHEJ_ligase_prk: DNA ligase D 244 849 3.0E-201 T 14-10-2018 IPR014143 DNA ligase D LH59_19425 209912bbe19afb86ae869734a56e2f7b 868 TIGRFAM TIGR02777 LigD_PE_dom: DNA ligase D, 3'-phosphoesterase domain 5 161 2.5E-68 T 14-10-2018 IPR014144 DNA ligase D, 3'-phosphoesterase domain LH59_19425 209912bbe19afb86ae869734a56e2f7b 868 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 579 821 3.2E-81 T 14-10-2018 IPR014145 DNA ligase D, polymerase domain LH59_19425 209912bbe19afb86ae869734a56e2f7b 868 Pfam PF01068 ATP dependent DNA ligase domain 233 414 1.4E-22 T 14-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 LH59_19425 209912bbe19afb86ae869734a56e2f7b 868 TIGRFAM TIGR02779 NHEJ_ligase_lig: DNA ligase D, ligase domain 231 531 2.9E-104 T 14-10-2018 IPR014146 DNA ligase D, ligase domain LH59_19425 209912bbe19afb86ae869734a56e2f7b 868 Gene3D G3DSA:3.90.920.30 585 861 1.3E-94 T 14-10-2018 LH59_19425 209912bbe19afb86ae869734a56e2f7b 868 Pfam PF13298 DNA polymerase Ligase (LigD) 36 140 2.1E-38 T 14-10-2018 IPR014144 DNA ligase D, 3'-phosphoesterase domain LH59_19425 209912bbe19afb86ae869734a56e2f7b 868 Gene3D G3DSA:3.30.470.30 256 371 6.9E-46 T 14-10-2018 LH59_19425 209912bbe19afb86ae869734a56e2f7b 868 SUPERFAMILY SSF56091 228 414 1.01E-46 T 14-10-2018 LH59_19425 209912bbe19afb86ae869734a56e2f7b 868 Gene3D G3DSA:3.30.1490.70 244 412 6.9E-46 T 14-10-2018 LH59_19425 209912bbe19afb86ae869734a56e2f7b 868 Pfam PF01896 DNA primase small subunit 696 764 4.0E-6 T 14-10-2018 IPR002755 DNA primase, small subunit GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 LH59_19425 209912bbe19afb86ae869734a56e2f7b 868 Pfam PF04679 ATP dependent DNA ligase C terminal region 435 525 1.8E-23 T 14-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 LH59_18240 7e68f8fd95988bf49f05401b66eba418 401 Pfam PF13000 Acetyl-coenzyme A transporter 1 10 95 9.0E-18 T 14-10-2018 IPR024371 Acetyl-coenzyme A transporter 1-like GO:0008521|GO:0016021 Reactome: R-HSA-425397|Reactome: R-HSA-5619061 LH59_18240 7e68f8fd95988bf49f05401b66eba418 401 SUPERFAMILY SSF103473 7 399 5.23E-25 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_18240 7e68f8fd95988bf49f05401b66eba418 401 TIGRFAM TIGR02718 sider_RhtX_FptX: siderophore transporter, RhtX/FptX family 8 391 4.1E-137 T 14-10-2018 IPR014090 Siderophore transporter, RhtX/FptX family LH59_18240 7e68f8fd95988bf49f05401b66eba418 401 Gene3D G3DSA:1.20.1250.20 4 398 3.7E-22 T 14-10-2018 LH59_06860 3002253a3120b27e7f24024306a71a0a 140 PIRSF PIRSF004638 1 140 5.6E-51 T 14-10-2018 IPR005265 Uncharacterised protein family UPF0093 LH59_06860 3002253a3120b27e7f24024306a71a0a 140 Pfam PF03653 Uncharacterised protein family (UPF0093) 2 140 1.7E-46 T 14-10-2018 IPR005265 Uncharacterised protein family UPF0093 LH59_20695 99a26a81d5e4e3d5d87ec30b330f0652 427 SUPERFAMILY SSF47384 174 256 1.8E-14 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 LH59_20695 99a26a81d5e4e3d5d87ec30b330f0652 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 387 400 6.4E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_20695 99a26a81d5e4e3d5d87ec30b330f0652 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 363 381 6.4E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_20695 99a26a81d5e4e3d5d87ec30b330f0652 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 332 346 6.4E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_20695 99a26a81d5e4e3d5d87ec30b330f0652 427 Pfam PF00512 His Kinase A (phospho-acceptor) domain 192 256 4.9E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_20695 99a26a81d5e4e3d5d87ec30b330f0652 427 SMART SM00387 295 403 3.6E-21 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_20695 99a26a81d5e4e3d5d87ec30b330f0652 427 Gene3D G3DSA:3.30.565.10 264 402 2.7E-25 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_20695 99a26a81d5e4e3d5d87ec30b330f0652 427 SMART SM00388 189 257 3.6E-10 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_20695 99a26a81d5e4e3d5d87ec30b330f0652 427 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 303 401 2.5E-14 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_20695 99a26a81d5e4e3d5d87ec30b330f0652 427 SUPERFAMILY SSF55874 265 401 6.16E-29 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_20695 99a26a81d5e4e3d5d87ec30b330f0652 427 Gene3D G3DSA:1.10.287.130 175 256 1.6E-12 T 14-10-2018 LH59_00940 1ac8739e3a82668b74d7ea270b971bb9 272 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 17 271 48.374 T 14-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 LH59_00940 1ac8739e3a82668b74d7ea270b971bb9 272 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 18 271 6.1E-113 T 14-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 LH59_00940 1ac8739e3a82668b74d7ea270b971bb9 272 Gene3D G3DSA:3.20.20.70 16 272 3.7E-108 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_00940 1ac8739e3a82668b74d7ea270b971bb9 272 SUPERFAMILY SSF51366 18 271 1.41E-82 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 LH59_00940 1ac8739e3a82668b74d7ea270b971bb9 272 Pfam PF00977 Histidine biosynthesis protein 21 254 4.1E-89 T 14-10-2018 IPR006062 Histidine biosynthesis GO:0000105 LH59_24020 402e4b37e547cf09cf26227ecb980506 589 SUPERFAMILY SSF52467 190 354 2.07E-41 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily LH59_24020 402e4b37e547cf09cf26227ecb980506 589 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 198 327 4.6E-26 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 LH59_24020 402e4b37e547cf09cf26227ecb980506 589 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 3 167 1.6E-48 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 LH59_24020 402e4b37e547cf09cf26227ecb980506 589 Gene3D G3DSA:3.40.50.970 357 587 2.7E-54 T 14-10-2018 LH59_24020 402e4b37e547cf09cf26227ecb980506 589 SUPERFAMILY SSF52518 364 565 4.83E-51 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold LH59_24020 402e4b37e547cf09cf26227ecb980506 589 Gene3D G3DSA:3.40.50.970 1 172 2.4E-57 T 14-10-2018 LH59_24020 402e4b37e547cf09cf26227ecb980506 589 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 387 542 9.9E-26 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 LH59_24020 402e4b37e547cf09cf26227ecb980506 589 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 424 443 - T 14-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 LH59_24020 402e4b37e547cf09cf26227ecb980506 589 Gene3D G3DSA:3.40.50.1220 186 341 7.5E-43 T 14-10-2018 LH59_24020 402e4b37e547cf09cf26227ecb980506 589 SUPERFAMILY SSF52518 3 175 1.49E-48 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold LH59_23915 89848d8325044e7956a19e5c487218ce 201 Gene3D G3DSA:3.90.226.10 1 199 1.8E-81 T 14-10-2018 LH59_23915 89848d8325044e7956a19e5c487218ce 201 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 7 197 39.815 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 LH59_23915 89848d8325044e7956a19e5c487218ce 201 PRINTS PR00127 Clp protease catalytic subunit P signature 115 134 2.1E-45 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 LH59_23915 89848d8325044e7956a19e5c487218ce 201 PRINTS PR00127 Clp protease catalytic subunit P signature 23 38 2.1E-45 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 LH59_23915 89848d8325044e7956a19e5c487218ce 201 PRINTS PR00127 Clp protease catalytic subunit P signature 172 191 2.1E-45 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 LH59_23915 89848d8325044e7956a19e5c487218ce 201 PRINTS PR00127 Clp protease catalytic subunit P signature 94 111 2.1E-45 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 LH59_23915 89848d8325044e7956a19e5c487218ce 201 PRINTS PR00127 Clp protease catalytic subunit P signature 63 83 2.1E-45 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 LH59_23915 89848d8325044e7956a19e5c487218ce 201 SUPERFAMILY SSF52096 15 198 1.49E-69 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily LH59_23915 89848d8325044e7956a19e5c487218ce 201 Pfam PF00574 Clp protease 17 196 6.7E-79 T 14-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA LH59_27080 792e87cb03d7b0d4e5bf28e2cd51ffea 212 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 5 181 9.5E-52 T 14-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 LH59_27080 792e87cb03d7b0d4e5bf28e2cd51ffea 212 Gene3D G3DSA:3.20.19.10 2 177 6.2E-57 T 14-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 LH59_27080 792e87cb03d7b0d4e5bf28e2cd51ffea 212 Pfam PF00694 Aconitase C-terminal domain 6 120 4.5E-29 T 14-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 LH59_27080 792e87cb03d7b0d4e5bf28e2cd51ffea 212 SUPERFAMILY SSF52016 3 177 5.1E-48 T 14-10-2018 LH59_11070 22abd07c52698efd14df42a19e3bc187 330 SUPERFAMILY SSF53067 16 143 2.98E-13 T 14-10-2018 LH59_11070 22abd07c52698efd14df42a19e3bc187 330 Pfam PF05134 Type II secretion system (T2SS), protein L 45 144 2.7E-6 T 14-10-2018 IPR024230 GspL, cytoplasmic actin-ATPase-like domain LH59_11070 22abd07c52698efd14df42a19e3bc187 330 Pfam PF12693 GspL periplasmic domain 176 317 2.3E-17 T 14-10-2018 IPR025691 GspL periplasmic domain LH59_11070 22abd07c52698efd14df42a19e3bc187 330 Gene3D G3DSA:3.30.420.380 16 157 1.3E-11 T 14-10-2018 LH59_00080 1e989a063c859c518478018fbebb3e99 352 Gene3D G3DSA:3.40.640.10 5 253 2.9E-70 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_00080 1e989a063c859c518478018fbebb3e99 352 PIRSF PIRSF017617 5 352 1.0E-103 T 14-10-2018 IPR023603 Threonine aldolase LH59_00080 1e989a063c859c518478018fbebb3e99 352 Gene3D G3DSA:3.90.1150.10 257 351 3.5E-24 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_00080 1e989a063c859c518478018fbebb3e99 352 Pfam PF01212 Beta-eliminating lyase 15 295 9.0E-77 T 14-10-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 LH59_00080 1e989a063c859c518478018fbebb3e99 352 SUPERFAMILY SSF53383 14 350 9.04E-94 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_03020 3851c9580073b2a920826e3fe05060f4 221 SUPERFAMILY SSF51391 6 208 8.76E-54 T 14-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 LH59_03020 3851c9580073b2a920826e3fe05060f4 221 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 10 207 1.9E-47 T 14-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 LH59_03020 3851c9580073b2a920826e3fe05060f4 221 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 8 214 23.83 T 14-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 LH59_03020 3851c9580073b2a920826e3fe05060f4 221 Gene3D G3DSA:3.20.20.70 6 213 1.4E-53 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_03020 3851c9580073b2a920826e3fe05060f4 221 Pfam PF02581 Thiamine monophosphate synthase 10 195 5.5E-51 T 14-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 LH59_26060 95ca59d15a4e70cf1916517a6fa4e3ff 287 Gene3D G3DSA:3.40.190.10 95 261 1.1E-48 T 14-10-2018 LH59_26060 95ca59d15a4e70cf1916517a6fa4e3ff 287 SUPERFAMILY SSF53850 89 282 4.81E-25 T 14-10-2018 LH59_26060 95ca59d15a4e70cf1916517a6fa4e3ff 287 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 64 1.3E-20 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_26060 95ca59d15a4e70cf1916517a6fa4e3ff 287 Gene3D G3DSA:3.40.190.10 162 255 1.1E-48 T 14-10-2018 LH59_26060 95ca59d15a4e70cf1916517a6fa4e3ff 287 Pfam PF03466 LysR substrate binding domain 88 281 3.1E-27 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_26060 95ca59d15a4e70cf1916517a6fa4e3ff 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 6.8E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_26060 95ca59d15a4e70cf1916517a6fa4e3ff 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 6.8E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_26060 95ca59d15a4e70cf1916517a6fa4e3ff 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 6.8E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_26060 95ca59d15a4e70cf1916517a6fa4e3ff 287 SUPERFAMILY SSF46785 3 110 5.08E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_26060 95ca59d15a4e70cf1916517a6fa4e3ff 287 Gene3D G3DSA:1.10.10.10 1 86 7.0E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_25595 75e8f95040bfde3bc69cd9bd7e8e7c20 259 Pfam PF14464 Prokaryotic homologs of the JAB domain 3 98 2.4E-18 T 14-10-2018 IPR028090 JAB domain, prokaryotic LH59_25595 75e8f95040bfde3bc69cd9bd7e8e7c20 259 SMART SM00232 1 118 0.002 T 14-10-2018 IPR000555 JAB1/MPN/MOV34 metalloenzyme domain GO:0005515 LH59_25595 75e8f95040bfde3bc69cd9bd7e8e7c20 259 Gene3D G3DSA:3.90.1720.10 120 257 3.5E-7 T 14-10-2018 LH59_25595 75e8f95040bfde3bc69cd9bd7e8e7c20 259 SUPERFAMILY SSF102712 3 101 3.66E-21 T 14-10-2018 LH59_25595 75e8f95040bfde3bc69cd9bd7e8e7c20 259 Gene3D G3DSA:3.40.140.10 1 113 1.3E-22 T 14-10-2018 LH59_25595 75e8f95040bfde3bc69cd9bd7e8e7c20 259 SUPERFAMILY SSF54001 120 255 1.77E-10 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily LH59_25595 75e8f95040bfde3bc69cd9bd7e8e7c20 259 Pfam PF00877 NlpC/P60 family 124 254 9.9E-15 T 14-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain LH59_09420 2764c5052e05f94d9c3a59c7f28ad58f 467 Gene3D G3DSA:3.30.499.20 4 286 1.9E-96 T 14-10-2018 LH59_09420 2764c5052e05f94d9c3a59c7f28ad58f 467 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 1 467 60.328 T 14-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 LH59_09420 2764c5052e05f94d9c3a59c7f28ad58f 467 ProSitePatterns PS00450 Aconitase family signature 1. 339 355 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 LH59_09420 2764c5052e05f94d9c3a59c7f28ad58f 467 SUPERFAMILY SSF53732 2 466 1.44E-165 T 14-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 LH59_09420 2764c5052e05f94d9c3a59c7f28ad58f 467 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 1 466 1.2E-237 T 14-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 LH59_09420 2764c5052e05f94d9c3a59c7f28ad58f 467 PRINTS PR00415 Aconitase family signature 108 116 8.6E-49 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 LH59_09420 2764c5052e05f94d9c3a59c7f28ad58f 467 PRINTS PR00415 Aconitase family signature 133 148 8.6E-49 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 LH59_09420 2764c5052e05f94d9c3a59c7f28ad58f 467 PRINTS PR00415 Aconitase family signature 209 222 8.6E-49 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 LH59_09420 2764c5052e05f94d9c3a59c7f28ad58f 467 PRINTS PR00415 Aconitase family signature 400 413 8.6E-49 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 LH59_09420 2764c5052e05f94d9c3a59c7f28ad58f 467 PRINTS PR00415 Aconitase family signature 195 208 8.6E-49 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 LH59_09420 2764c5052e05f94d9c3a59c7f28ad58f 467 PRINTS PR00415 Aconitase family signature 82 95 8.6E-49 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 LH59_09420 2764c5052e05f94d9c3a59c7f28ad58f 467 PRINTS PR00415 Aconitase family signature 119 132 8.6E-49 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 LH59_09420 2764c5052e05f94d9c3a59c7f28ad58f 467 PRINTS PR00415 Aconitase family signature 343 354 8.6E-49 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 LH59_09420 2764c5052e05f94d9c3a59c7f28ad58f 467 PRINTS PR00415 Aconitase family signature 286 300 8.6E-49 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 LH59_09420 2764c5052e05f94d9c3a59c7f28ad58f 467 ProSitePatterns PS01244 Aconitase family signature 2. 400 413 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 LH59_09420 2764c5052e05f94d9c3a59c7f28ad58f 467 Gene3D G3DSA:3.30.499.10 326 467 7.2E-50 T 14-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 LH59_09420 2764c5052e05f94d9c3a59c7f28ad58f 467 Pfam PF00330 Aconitase family (aconitate hydratase) 7 458 8.4E-160 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 LH59_23800 74ecda6675c661ef67aa5efe09d707bf 747 TIGRFAM TIGR03396 PC_PLC: phospholipase C, phosphocholine-specific 3 743 3.1E-288 T 14-10-2018 IPR017767 Bacterial phospholipase C, phosphocholine-specific GO:0034480 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 LH59_23800 74ecda6675c661ef67aa5efe09d707bf 747 Gene3D G3DSA:3.40.720.10 35 202 2.6E-30 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 LH59_23800 74ecda6675c661ef67aa5efe09d707bf 747 Pfam PF04185 Phosphoesterase family 46 476 1.2E-105 T 14-10-2018 IPR007312 Phosphoesterase GO:0016788 LH59_23800 74ecda6675c661ef67aa5efe09d707bf 747 Pfam PF05506 Domain of unknown function (DUF756) 647 729 3.0E-22 T 14-10-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 LH59_23800 74ecda6675c661ef67aa5efe09d707bf 747 Pfam PF05506 Domain of unknown function (DUF756) 548 636 8.2E-25 T 14-10-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 LH59_09750 b530cb45f371801e23828577dd54ce99 317 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 41 252 3.6E-13 T 14-10-2018 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0016788 LH59_09750 b530cb45f371801e23828577dd54ce99 317 SUPERFAMILY SSF53187 16 313 3.64E-51 T 14-10-2018 LH59_09750 b530cb45f371801e23828577dd54ce99 317 Gene3D G3DSA:3.40.630.10 13 317 1.7E-55 T 14-10-2018 LH59_05560 fd4088c8d664000631d326f94e37b1f5 375 SMART SM00922 149 247 5.7E-27 T 14-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal LH59_05560 fd4088c8d664000631d326f94e37b1f5 375 Pfam PF13378 Enolase C-terminal domain-like 153 361 2.4E-57 T 14-10-2018 IPR029065 Enolase C-terminal domain-like LH59_05560 fd4088c8d664000631d326f94e37b1f5 375 SUPERFAMILY SSF51604 115 367 2.49E-70 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily LH59_05560 fd4088c8d664000631d326f94e37b1f5 375 SUPERFAMILY SSF54826 4 127 3.39E-29 T 14-10-2018 LH59_05560 fd4088c8d664000631d326f94e37b1f5 375 Gene3D G3DSA:3.20.20.120 126 359 5.3E-72 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily LH59_05560 fd4088c8d664000631d326f94e37b1f5 375 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 19 127 9.2E-22 T 14-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain LH59_05560 fd4088c8d664000631d326f94e37b1f5 375 Gene3D G3DSA:3.30.390.10 2 125 7.8E-33 T 14-10-2018 IPR029017 Enolase-like, N-terminal LH59_25100 d8aaf475b6151b3dc8fec6cf7bf7d0c4 367 Gene3D G3DSA:3.40.1610.10 3 224 2.9E-21 T 14-10-2018 IPR027479 Protein of unknown function DUF917, N-terminal LH59_25100 d8aaf475b6151b3dc8fec6cf7bf7d0c4 367 SUPERFAMILY SSF160991 3 356 2.09E-78 T 14-10-2018 LH59_25100 d8aaf475b6151b3dc8fec6cf7bf7d0c4 367 Pfam PF06032 Protein of unknown function (DUF917) 8 330 1.1E-55 T 14-10-2018 IPR010318 Protein of unknown function DUF917 LH59_02090 a29171df1facef74fbf5d011f6d83d5c 376 Gene3D G3DSA:3.40.630.10 16 364 4.1E-111 T 14-10-2018 LH59_02090 a29171df1facef74fbf5d011f6d83d5c 376 Gene3D G3DSA:3.30.70.360 181 288 4.1E-111 T 14-10-2018 LH59_02090 a29171df1facef74fbf5d011f6d83d5c 376 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 75 84 - T 14-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 LH59_02090 a29171df1facef74fbf5d011f6d83d5c 376 PIRSF PIRSF037238 1 376 2.4E-139 T 14-10-2018 IPR017150 Peptidase M20, glutamate carboxypeptidase LH59_02090 a29171df1facef74fbf5d011f6d83d5c 376 SUPERFAMILY SSF53187 7 376 7.04E-50 T 14-10-2018 LH59_02090 a29171df1facef74fbf5d011f6d83d5c 376 Pfam PF07687 Peptidase dimerisation domain 178 273 1.0E-17 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain LH59_02090 a29171df1facef74fbf5d011f6d83d5c 376 SUPERFAMILY SSF55031 181 291 2.69E-21 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain LH59_02090 a29171df1facef74fbf5d011f6d83d5c 376 Pfam PF01546 Peptidase family M20/M25/M40 77 373 2.2E-29 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 LH59_14515 f19737cda0bb15cba137231a245f35ad 219 SUPERFAMILY SSF53056 2 210 5.63E-61 T 14-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 LH59_14515 f19737cda0bb15cba137231a245f35ad 219 Pfam PF00484 Carbonic anhydrase 37 196 5.3E-46 T 14-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 LH59_14515 f19737cda0bb15cba137231a245f35ad 219 SMART SM00947 30 201 3.1E-55 T 14-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 LH59_14515 f19737cda0bb15cba137231a245f35ad 219 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 87 107 - T 14-10-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 LH59_14515 f19737cda0bb15cba137231a245f35ad 219 Gene3D G3DSA:3.40.1050.10 1 208 1.2E-70 T 14-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 LH59_26170 84405ba3a459fe55144134c113573b07 327 Gene3D G3DSA:3.40.190.150 32 317 7.9E-101 T 14-10-2018 LH59_26170 84405ba3a459fe55144134c113573b07 327 Gene3D G3DSA:3.40.190.10 130 252 7.9E-101 T 14-10-2018 LH59_26170 84405ba3a459fe55144134c113573b07 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 323 4.4E-82 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_26170 84405ba3a459fe55144134c113573b07 327 SUPERFAMILY SSF53850 117 287 3.8E-10 T 14-10-2018 LH59_26170 84405ba3a459fe55144134c113573b07 327 PIRSF PIRSF017082 1 326 4.7E-73 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_04455 8aaaa48217e504af6e002641a0711dfb 483 Gene3D G3DSA:3.30.450.20 152 253 1.4E-21 T 14-10-2018 LH59_04455 8aaaa48217e504af6e002641a0711dfb 483 Gene3D G3DSA:3.30.450.20 11 151 5.2E-27 T 14-10-2018 LH59_04455 8aaaa48217e504af6e002641a0711dfb 483 SUPERFAMILY SSF55785 155 255 2.97E-26 T 14-10-2018 IPR035965 PAS domain superfamily LH59_04455 8aaaa48217e504af6e002641a0711dfb 483 SMART SM00283 247 467 4.2E-38 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 LH59_04455 8aaaa48217e504af6e002641a0711dfb 483 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 285 437 4.9E-45 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 LH59_04455 8aaaa48217e504af6e002641a0711dfb 483 Pfam PF08447 PAS fold 166 251 6.4E-16 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 LH59_04455 8aaaa48217e504af6e002641a0711dfb 483 Pfam PF08447 PAS fold 44 129 1.7E-17 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 LH59_04455 8aaaa48217e504af6e002641a0711dfb 483 SUPERFAMILY SSF58104 263 453 4.05E-48 T 14-10-2018 LH59_04455 8aaaa48217e504af6e002641a0711dfb 483 SUPERFAMILY SSF55785 32 137 1.66E-28 T 14-10-2018 IPR035965 PAS domain superfamily LH59_04455 8aaaa48217e504af6e002641a0711dfb 483 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 29 141 2.1E-18 T 14-10-2018 IPR000014 PAS domain LH59_04455 8aaaa48217e504af6e002641a0711dfb 483 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 153 264 6.5E-19 T 14-10-2018 IPR000014 PAS domain LH59_04455 8aaaa48217e504af6e002641a0711dfb 483 SMART SM00086 216 258 3.9E-5 T 14-10-2018 IPR001610 PAC motif LH59_04455 8aaaa48217e504af6e002641a0711dfb 483 SMART SM00086 94 136 1.1E-4 T 14-10-2018 IPR001610 PAC motif LH59_04455 8aaaa48217e504af6e002641a0711dfb 483 SMART SM00091 21 89 0.013 T 14-10-2018 IPR000014 PAS domain LH59_04455 8aaaa48217e504af6e002641a0711dfb 483 SMART SM00091 143 210 0.84 T 14-10-2018 IPR000014 PAS domain LH59_04455 8aaaa48217e504af6e002641a0711dfb 483 Gene3D G3DSA:1.10.287.950 254 467 9.7E-49 T 14-10-2018 LH59_26690 85e58744f3ee20aef477e147d43e808b 159 Hamap MF_00048 UPF0102 protein YraN [yraN]. 42 157 20.41 T 14-10-2018 IPR003509 Uncharacterised protein family UPF0102 LH59_26690 85e58744f3ee20aef477e147d43e808b 159 Pfam PF02021 Uncharacterised protein family UPF0102 50 143 7.9E-23 T 14-10-2018 IPR003509 Uncharacterised protein family UPF0102 LH59_26690 85e58744f3ee20aef477e147d43e808b 159 Gene3D G3DSA:3.40.1350.10 48 158 1.9E-26 T 14-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 LH59_26690 85e58744f3ee20aef477e147d43e808b 159 TIGRFAM TIGR00252 TIGR00252: TIGR00252 family protein 40 157 9.6E-24 T 14-10-2018 IPR003509 Uncharacterised protein family UPF0102 LH59_26690 85e58744f3ee20aef477e147d43e808b 159 SUPERFAMILY SSF52980 44 148 8.85E-14 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 LH59_27955 b3d0603a7090d1ce2ec9ae95ecefef35 774 SUPERFAMILY SSF55785 405 539 3.14E-10 T 14-10-2018 IPR035965 PAS domain superfamily LH59_27955 b3d0603a7090d1ce2ec9ae95ecefef35 774 SUPERFAMILY SSF47384 536 611 1.55E-9 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 LH59_27955 b3d0603a7090d1ce2ec9ae95ecefef35 774 Gene3D G3DSA:3.30.450.20 407 543 1.7E-11 T 14-10-2018 LH59_27955 b3d0603a7090d1ce2ec9ae95ecefef35 774 Pfam PF05226 CHASE2 domain 23 304 7.4E-52 T 14-10-2018 IPR007890 CHASE2 LH59_27955 b3d0603a7090d1ce2ec9ae95ecefef35 774 Gene3D G3DSA:3.30.565.10 615 771 5.6E-39 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_27955 b3d0603a7090d1ce2ec9ae95ecefef35 774 PRINTS PR00344 Bacterial sensor protein C-terminal signature 693 707 1.6E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_27955 b3d0603a7090d1ce2ec9ae95ecefef35 774 PRINTS PR00344 Bacterial sensor protein C-terminal signature 711 721 1.6E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_27955 b3d0603a7090d1ce2ec9ae95ecefef35 774 PRINTS PR00344 Bacterial sensor protein C-terminal signature 752 765 1.6E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_27955 b3d0603a7090d1ce2ec9ae95ecefef35 774 PRINTS PR00344 Bacterial sensor protein C-terminal signature 728 746 1.6E-15 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_27955 b3d0603a7090d1ce2ec9ae95ecefef35 774 Gene3D G3DSA:1.10.287.130 544 614 8.4E-9 T 14-10-2018 LH59_27955 b3d0603a7090d1ce2ec9ae95ecefef35 774 SMART SM00388 547 612 1.9E-4 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_27955 b3d0603a7090d1ce2ec9ae95ecefef35 774 SUPERFAMILY SSF55874 602 769 4.71E-40 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_27955 b3d0603a7090d1ce2ec9ae95ecefef35 774 SMART SM01080 35 310 5.1E-73 T 14-10-2018 IPR007890 CHASE2 LH59_27955 b3d0603a7090d1ce2ec9ae95ecefef35 774 PIRSF PIRSF037347 3 771 7.1E-268 T 14-10-2018 IPR017181 Signal transduction histidine kinase, CHASE2 sensor domain-containing, predicted LH59_27955 b3d0603a7090d1ce2ec9ae95ecefef35 774 SMART SM00387 656 768 2.0E-36 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_27955 b3d0603a7090d1ce2ec9ae95ecefef35 774 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 656 766 2.9E-22 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_25490 02b1b7bad1bdbd0b43c56ae7eab1b9df 236 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_25490 02b1b7bad1bdbd0b43c56ae7eab1b9df 236 SUPERFAMILY SSF52540 2 219 2.31E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_25490 02b1b7bad1bdbd0b43c56ae7eab1b9df 236 Pfam PF00005 ABC transporter 17 161 5.8E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_25490 02b1b7bad1bdbd0b43c56ae7eab1b9df 236 Gene3D G3DSA:3.40.50.300 1 226 1.1E-57 T 14-10-2018 LH59_25490 02b1b7bad1bdbd0b43c56ae7eab1b9df 236 SMART SM00382 26 209 7.1E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_18340 ca942e18ce715d5a3dbf4a3a7a0d2c00 316 PIRSF PIRSF017082 2 316 4.3E-82 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_18340 ca942e18ce715d5a3dbf4a3a7a0d2c00 316 Gene3D G3DSA:3.40.190.150 23 306 5.9E-110 T 14-10-2018 LH59_18340 ca942e18ce715d5a3dbf4a3a7a0d2c00 316 Gene3D G3DSA:3.40.190.10 120 241 5.9E-110 T 14-10-2018 LH59_18340 ca942e18ce715d5a3dbf4a3a7a0d2c00 316 SUPERFAMILY SSF53850 106 278 3.31E-19 T 14-10-2018 LH59_18340 ca942e18ce715d5a3dbf4a3a7a0d2c00 316 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 43 312 3.3E-85 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_16640 c86a203b76af4415b7558424a3d99b1c 183 Hamap MF_00105 Transcription elongation factor GreA [greA]. 27 180 27.208 T 14-10-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 LH59_16640 c86a203b76af4415b7558424a3d99b1c 183 SUPERFAMILY SSF46557 28 102 6.41E-27 T 14-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 LH59_16640 c86a203b76af4415b7558424a3d99b1c 183 TIGRFAM TIGR01461 greB: transcription elongation factor GreB 27 182 1.6E-64 T 14-10-2018 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 LH59_16640 c86a203b76af4415b7558424a3d99b1c 183 Gene3D G3DSA:3.10.50.30 104 183 1.8E-26 T 14-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 LH59_16640 c86a203b76af4415b7558424a3d99b1c 183 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 108 181 9.7E-24 T 14-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 LH59_16640 c86a203b76af4415b7558424a3d99b1c 183 Hamap MF_00930 Transcription elongation factor GreB [greB]. 26 182 52.067 T 14-10-2018 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 LH59_16640 c86a203b76af4415b7558424a3d99b1c 183 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 42 73 - T 14-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 LH59_16640 c86a203b76af4415b7558424a3d99b1c 183 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 145 161 - T 14-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 LH59_16640 c86a203b76af4415b7558424a3d99b1c 183 PIRSF PIRSF006092 25 183 2.5E-43 T 14-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 LH59_16640 c86a203b76af4415b7558424a3d99b1c 183 Pfam PF03449 Transcription elongation factor, N-terminal 29 99 9.8E-25 T 14-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 LH59_16640 c86a203b76af4415b7558424a3d99b1c 183 Gene3D G3DSA:1.10.287.180 27 101 4.9E-27 T 14-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 LH59_16640 c86a203b76af4415b7558424a3d99b1c 183 SUPERFAMILY SSF54534 106 181 5.62E-20 T 14-10-2018 LH59_23885 1d252a38b5228b229a24a2a6417ba631 278 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 235 250 3.7E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 LH59_23885 1d252a38b5228b229a24a2a6417ba631 278 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 250 266 3.7E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 LH59_23885 1d252a38b5228b229a24a2a6417ba631 278 Gene3D G3DSA:1.10.10.60 168 272 3.8E-23 T 14-10-2018 LH59_23885 1d252a38b5228b229a24a2a6417ba631 278 SMART SM00342 184 266 1.4E-24 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_23885 1d252a38b5228b229a24a2a6417ba631 278 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 221 262 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 LH59_23885 1d252a38b5228b229a24a2a6417ba631 278 SUPERFAMILY SSF46689 220 267 1.52E-8 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_23885 1d252a38b5228b229a24a2a6417ba631 278 Pfam PF12833 Helix-turn-helix domain 190 267 5.7E-24 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_23885 1d252a38b5228b229a24a2a6417ba631 278 SUPERFAMILY SSF51182 40 189 4.45E-11 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_23885 1d252a38b5228b229a24a2a6417ba631 278 Gene3D G3DSA:2.60.120.10 26 104 1.2E-5 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_06055 4b24bdad1eb37458ff16e926e3baec2a 298 Gene3D G3DSA:3.40.190.10 90 274 9.2E-22 T 14-10-2018 LH59_06055 4b24bdad1eb37458ff16e926e3baec2a 298 Pfam PF03466 LysR substrate binding domain 88 288 8.5E-41 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_06055 4b24bdad1eb37458ff16e926e3baec2a 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 5.2E-19 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_06055 4b24bdad1eb37458ff16e926e3baec2a 298 SUPERFAMILY SSF46785 1 109 3.83E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_06055 4b24bdad1eb37458ff16e926e3baec2a 298 Gene3D G3DSA:1.10.10.10 1 84 5.2E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_06055 4b24bdad1eb37458ff16e926e3baec2a 298 SUPERFAMILY SSF53850 89 287 5.43E-36 T 14-10-2018 LH59_06055 4b24bdad1eb37458ff16e926e3baec2a 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.9E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_06055 4b24bdad1eb37458ff16e926e3baec2a 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.9E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_06055 4b24bdad1eb37458ff16e926e3baec2a 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.9E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_06055 4b24bdad1eb37458ff16e926e3baec2a 298 Gene3D G3DSA:3.40.190.10 163 264 9.2E-22 T 14-10-2018 LH59_01950 69fb4257aa5816162e401ddd57731675 293 Gene3D G3DSA:1.10.10.10 1 93 2.0E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_01950 69fb4257aa5816162e401ddd57731675 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 7.4E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_01950 69fb4257aa5816162e401ddd57731675 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 7.4E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_01950 69fb4257aa5816162e401ddd57731675 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 7.4E-10 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_01950 69fb4257aa5816162e401ddd57731675 293 Gene3D G3DSA:3.40.190.10 95 284 1.0E-45 T 14-10-2018 LH59_01950 69fb4257aa5816162e401ddd57731675 293 Pfam PF03466 LysR substrate binding domain 87 289 1.5E-37 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_01950 69fb4257aa5816162e401ddd57731675 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 6.2E-23 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_01950 69fb4257aa5816162e401ddd57731675 293 SUPERFAMILY SSF46785 1 87 1.44E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_01950 69fb4257aa5816162e401ddd57731675 293 SUPERFAMILY SSF53850 87 292 8.01E-34 T 14-10-2018 LH59_01950 69fb4257aa5816162e401ddd57731675 293 Gene3D G3DSA:3.40.190.10 163 266 1.0E-45 T 14-10-2018 LH59_12530 828a6a48d1a9cb8fce7e15f1167ad56a 416 Gene3D G3DSA:3.40.50.2300 29 357 5.4E-80 T 14-10-2018 LH59_12530 828a6a48d1a9cb8fce7e15f1167ad56a 416 Pfam PF13458 Periplasmic binding protein 27 359 1.1E-52 T 14-10-2018 IPR028081 Leucine-binding protein domain LH59_12530 828a6a48d1a9cb8fce7e15f1167ad56a 416 SUPERFAMILY SSF53822 27 412 1.53E-75 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_12530 828a6a48d1a9cb8fce7e15f1167ad56a 416 Gene3D G3DSA:3.40.50.2300 162 294 5.4E-80 T 14-10-2018 LH59_16175 68c5da8c202e2acf6fc46dceb8b5e4f3 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 321 6.9E-76 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_16175 68c5da8c202e2acf6fc46dceb8b5e4f3 328 PIRSF PIRSF017082 1 327 7.1E-76 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_16175 68c5da8c202e2acf6fc46dceb8b5e4f3 328 Gene3D G3DSA:3.40.190.10 129 253 2.1E-108 T 14-10-2018 LH59_16175 68c5da8c202e2acf6fc46dceb8b5e4f3 328 SUPERFAMILY SSF53850 117 290 8.68E-11 T 14-10-2018 LH59_16175 68c5da8c202e2acf6fc46dceb8b5e4f3 328 Gene3D G3DSA:3.40.190.150 31 317 2.1E-108 T 14-10-2018 LH59_27215 a655eb344decf4e4c3319a7702740f57 270 SUPERFAMILY SSF53822 51 270 2.83E-37 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_27215 a655eb344decf4e4c3319a7702740f57 270 Gene3D G3DSA:3.40.50.2300 102 230 7.0E-40 T 14-10-2018 LH59_27215 a655eb344decf4e4c3319a7702740f57 270 Gene3D G3DSA:3.40.50.2300 29 258 7.0E-40 T 14-10-2018 LH59_27215 a655eb344decf4e4c3319a7702740f57 270 Pfam PF13377 Periplasmic binding protein-like domain 111 270 1.5E-26 T 14-10-2018 LH59_15740 eb3728443752bb40cd974be17cc30fba 428 SUPERFAMILY SSF53383 70 426 6.69E-88 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_15740 eb3728443752bb40cd974be17cc30fba 428 PIRSF PIRSF001434 4 427 1.1E-124 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 LH59_15740 eb3728443752bb40cd974be17cc30fba 428 Gene3D G3DSA:3.40.640.10 16 289 3.6E-67 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_15740 eb3728443752bb40cd974be17cc30fba 428 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 233 247 - T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 LH59_15740 eb3728443752bb40cd974be17cc30fba 428 Gene3D G3DSA:3.90.1150.10 291 428 7.3E-44 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_15740 eb3728443752bb40cd974be17cc30fba 428 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 22 424 8.6E-98 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 LH59_17140 c02732e5aeac717486810d522db73752 273 SMART SM00382 34 235 1.7E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_17140 c02732e5aeac717486810d522db73752 273 Gene3D G3DSA:3.40.50.300 1 262 3.5E-62 T 14-10-2018 LH59_17140 c02732e5aeac717486810d522db73752 273 Pfam PF00005 ABC transporter 26 187 6.2E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_17140 c02732e5aeac717486810d522db73752 273 SUPERFAMILY SSF52540 8 258 8.66E-64 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_17140 c02732e5aeac717486810d522db73752 273 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 236 258 6.8E-12 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal LH59_02140 bcbcd0c5988d6b2f625251711bd7e07c 537 SUPERFAMILY SSF53850 17 517 2.35E-125 T 14-10-2018 LH59_02140 bcbcd0c5988d6b2f625251711bd7e07c 537 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 64 448 2.6E-88 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain LH59_02140 bcbcd0c5988d6b2f625251711bd7e07c 537 Gene3D G3DSA:3.40.190.10 29 286 5.1E-125 T 14-10-2018 LH59_02140 bcbcd0c5988d6b2f625251711bd7e07c 537 Gene3D G3DSA:3.10.105.10 287 515 5.1E-125 T 14-10-2018 LH59_02140 bcbcd0c5988d6b2f625251711bd7e07c 537 PIRSF PIRSF002741 11 524 3.4E-92 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 LH59_02140 bcbcd0c5988d6b2f625251711bd7e07c 537 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 70 91 - T 14-10-2018 IPR023765 Solute-binding protein family 5, conserved site LH59_02140 bcbcd0c5988d6b2f625251711bd7e07c 537 Gene3D G3DSA:3.90.76.10 55 176 5.1E-125 T 14-10-2018 LH59_02590 f0106e201c0661cd351c4cf7aa5ba4bf 520 SUPERFAMILY SSF48179 299 511 4.76E-54 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 LH59_02590 f0106e201c0661cd351c4cf7aa5ba4bf 520 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 36 201 1.2E-30 T 14-10-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 LH59_02590 f0106e201c0661cd351c4cf7aa5ba4bf 520 PRINTS PR00084 Mannitol dehydrogenase signature 193 206 2.1E-15 T 14-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 LH59_02590 f0106e201c0661cd351c4cf7aa5ba4bf 520 PRINTS PR00084 Mannitol dehydrogenase signature 232 245 2.1E-15 T 14-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 LH59_02590 f0106e201c0661cd351c4cf7aa5ba4bf 520 PRINTS PR00084 Mannitol dehydrogenase signature 37 47 2.1E-15 T 14-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 LH59_02590 f0106e201c0661cd351c4cf7aa5ba4bf 520 PRINTS PR00084 Mannitol dehydrogenase signature 262 277 2.1E-15 T 14-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 LH59_02590 f0106e201c0661cd351c4cf7aa5ba4bf 520 Gene3D G3DSA:1.10.1040.10 296 515 2.3E-66 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 LH59_02590 f0106e201c0661cd351c4cf7aa5ba4bf 520 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 231 454 5.6E-73 T 14-10-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 LH59_02590 f0106e201c0661cd351c4cf7aa5ba4bf 520 SUPERFAMILY SSF51735 11 296 3.94E-95 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_02590 f0106e201c0661cd351c4cf7aa5ba4bf 520 Gene3D G3DSA:3.40.50.720 9 295 6.7E-104 T 14-10-2018 LH59_05390 7cacfd1af62a44269f52479c941aee5a 514 Pfam PF00672 HAMP domain 210 256 1.8E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_05390 7cacfd1af62a44269f52479c941aee5a 514 SMART SM00304 209 261 2.4E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_05390 7cacfd1af62a44269f52479c941aee5a 514 Gene3D G3DSA:3.30.450.20 32 186 1.6E-39 T 14-10-2018 LH59_05390 7cacfd1af62a44269f52479c941aee5a 514 Pfam PF17200 Single Cache domain 2 38 185 8.8E-34 T 14-10-2018 IPR033480 Single Cache domain 2 LH59_05390 7cacfd1af62a44269f52479c941aee5a 514 SMART SM00283 262 509 2.0E-83 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 LH59_05390 7cacfd1af62a44269f52479c941aee5a 514 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 322 477 1.7E-46 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 LH59_05390 7cacfd1af62a44269f52479c941aee5a 514 SMART SM01049 33 126 4.1E-22 T 14-10-2018 IPR033480 Single Cache domain 2 LH59_05390 7cacfd1af62a44269f52479c941aee5a 514 SUPERFAMILY SSF58104 229 510 1.29E-67 T 14-10-2018 LH59_05390 7cacfd1af62a44269f52479c941aee5a 514 Gene3D G3DSA:1.10.287.950 208 511 4.2E-81 T 14-10-2018 LH59_05390 7cacfd1af62a44269f52479c941aee5a 514 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 389 418 1.1E-51 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_05390 7cacfd1af62a44269f52479c941aee5a 514 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 283 312 1.1E-51 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_05390 7cacfd1af62a44269f52479c941aee5a 514 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 437 466 1.1E-51 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_05390 7cacfd1af62a44269f52479c941aee5a 514 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 360 387 1.1E-51 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_05390 7cacfd1af62a44269f52479c941aee5a 514 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 183 203 1.1E-51 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_27735 aee99031bc8ebf5a66483e17c1571632 133 SUPERFAMILY SSF53137 18 133 9.16E-47 T 14-10-2018 LH59_27735 aee99031bc8ebf5a66483e17c1571632 133 ProSitePatterns PS00054 Ribosomal protein S11 signature. 101 123 - T 14-10-2018 IPR018102 Ribosomal S11, conserved site LH59_27735 aee99031bc8ebf5a66483e17c1571632 133 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 14 130 3.5E-55 T 14-10-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_27735 aee99031bc8ebf5a66483e17c1571632 133 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 133 32.814 T 14-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 LH59_27735 aee99031bc8ebf5a66483e17c1571632 133 PIRSF PIRSF002131 1 133 3.4E-52 T 14-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 LH59_27735 aee99031bc8ebf5a66483e17c1571632 133 Gene3D G3DSA:3.30.420.80 6 133 3.2E-54 T 14-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 LH59_27735 aee99031bc8ebf5a66483e17c1571632 133 Pfam PF00411 Ribosomal protein S11 23 132 6.6E-50 T 14-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 LH59_25240 350702961357d91fcab375eca8fe92f0 404 Gene3D G3DSA:3.40.50.2300 33 333 5.4E-113 T 14-10-2018 LH59_25240 350702961357d91fcab375eca8fe92f0 404 Pfam PF13458 Periplasmic binding protein 33 368 4.2E-89 T 14-10-2018 IPR028081 Leucine-binding protein domain LH59_25240 350702961357d91fcab375eca8fe92f0 404 SUPERFAMILY SSF53822 33 403 5.0E-89 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_25240 350702961357d91fcab375eca8fe92f0 404 Gene3D G3DSA:3.40.50.2300 152 283 5.4E-113 T 14-10-2018 LH59_08120 ac4f753bf617dd0604ee1f4ceccb1930 434 SUPERFAMILY SSF55347 137 302 4.38E-53 T 14-10-2018 LH59_08120 ac4f753bf617dd0604ee1f4ceccb1930 434 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 183 205 - T 14-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 LH59_08120 ac4f753bf617dd0604ee1f4ceccb1930 434 Pfam PF01842 ACT domain 354 419 2.5E-15 T 14-10-2018 IPR002912 ACT domain LH59_08120 ac4f753bf617dd0604ee1f4ceccb1930 434 PIRSF PIRSF000098 1 433 5.6E-163 T 14-10-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 LH59_08120 ac4f753bf617dd0604ee1f4ceccb1930 434 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 129 3.3E-20 T 14-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 LH59_08120 ac4f753bf617dd0604ee1f4ceccb1930 434 SUPERFAMILY SSF55021 353 422 1.3E-14 T 14-10-2018 LH59_08120 ac4f753bf617dd0604ee1f4ceccb1930 434 Gene3D G3DSA:3.30.360.10 136 348 3.3E-169 T 14-10-2018 LH59_08120 ac4f753bf617dd0604ee1f4ceccb1930 434 SUPERFAMILY SSF51735 1 158 1.34E-36 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_08120 ac4f753bf617dd0604ee1f4ceccb1930 434 Gene3D G3DSA:3.30.70.260 349 421 3.3E-169 T 14-10-2018 LH59_08120 ac4f753bf617dd0604ee1f4ceccb1930 434 Pfam PF00742 Homoserine dehydrogenase 137 315 4.3E-65 T 14-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 LH59_08120 ac4f753bf617dd0604ee1f4ceccb1930 434 Gene3D G3DSA:3.40.50.720 5 340 3.3E-169 T 14-10-2018 LH59_09900 6f1464631352df18e4f4c605e030a26e 268 Gene3D G3DSA:1.10.10.60 165 268 7.2E-18 T 14-10-2018 LH59_09900 6f1464631352df18e4f4c605e030a26e 268 SUPERFAMILY SSF46689 218 264 1.79E-6 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_09900 6f1464631352df18e4f4c605e030a26e 268 Pfam PF12833 Helix-turn-helix domain 190 265 4.0E-19 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_09900 6f1464631352df18e4f4c605e030a26e 268 Pfam PF02311 AraC-like ligand binding domain 37 149 4.5E-7 T 14-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 LH59_09900 6f1464631352df18e4f4c605e030a26e 268 SMART SM00342 181 263 1.2E-17 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_09900 6f1464631352df18e4f4c605e030a26e 268 Gene3D G3DSA:2.60.120.10 14 110 4.2E-10 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_09900 6f1464631352df18e4f4c605e030a26e 268 SUPERFAMILY SSF51182 21 188 3.88E-22 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_15600 d3688804b76998f0d15da63cc6f40c4a 289 SUPERFAMILY SSF46785 7 112 4.35E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_15600 d3688804b76998f0d15da63cc6f40c4a 289 Gene3D G3DSA:3.40.190.10 102 280 7.6E-35 T 14-10-2018 LH59_15600 d3688804b76998f0d15da63cc6f40c4a 289 SUPERFAMILY SSF53850 95 287 6.7E-23 T 14-10-2018 LH59_15600 d3688804b76998f0d15da63cc6f40c4a 289 Pfam PF03466 LysR substrate binding domain 95 284 3.4E-22 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_15600 d3688804b76998f0d15da63cc6f40c4a 289 Gene3D G3DSA:1.10.10.10 6 93 8.6E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_15600 d3688804b76998f0d15da63cc6f40c4a 289 Gene3D G3DSA:3.40.190.10 164 254 7.6E-35 T 14-10-2018 LH59_15600 d3688804b76998f0d15da63cc6f40c4a 289 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 65 4.3E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_16755 12cf25d5d8a4a0687bc4bafac0b24656 317 Gene3D G3DSA:3.40.50.80 98 217 1.2E-29 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain LH59_16755 12cf25d5d8a4a0687bc4bafac0b24656 317 Gene3D G3DSA:3.10.20.30 228 317 7.0E-22 T 14-10-2018 IPR012675 Beta-grasp domain superfamily LH59_16755 12cf25d5d8a4a0687bc4bafac0b24656 317 Gene3D G3DSA:2.40.30.10 1 96 1.0E-28 T 14-10-2018 LH59_16755 12cf25d5d8a4a0687bc4bafac0b24656 317 SUPERFAMILY SSF52343 98 215 6.29E-28 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain LH59_16755 12cf25d5d8a4a0687bc4bafac0b24656 317 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 239 308 4.2E-9 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 LH59_16755 12cf25d5d8a4a0687bc4bafac0b24656 317 SUPERFAMILY SSF54292 207 316 1.04E-23 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 LH59_16755 12cf25d5d8a4a0687bc4bafac0b24656 317 PRINTS PR00409 Phthalate dioxygenase reductase family signature 133 142 4.8E-46 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 LH59_16755 12cf25d5d8a4a0687bc4bafac0b24656 317 PRINTS PR00409 Phthalate dioxygenase reductase family signature 26 36 4.8E-46 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 LH59_16755 12cf25d5d8a4a0687bc4bafac0b24656 317 PRINTS PR00409 Phthalate dioxygenase reductase family signature 108 127 4.8E-46 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 LH59_16755 12cf25d5d8a4a0687bc4bafac0b24656 317 PRINTS PR00409 Phthalate dioxygenase reductase family signature 72 86 4.8E-46 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 LH59_16755 12cf25d5d8a4a0687bc4bafac0b24656 317 PRINTS PR00409 Phthalate dioxygenase reductase family signature 48 62 4.8E-46 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 LH59_16755 12cf25d5d8a4a0687bc4bafac0b24656 317 PRINTS PR00409 Phthalate dioxygenase reductase family signature 86 100 4.8E-46 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 LH59_16755 12cf25d5d8a4a0687bc4bafac0b24656 317 PRINTS PR00409 Phthalate dioxygenase reductase family signature 187 195 4.8E-46 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 LH59_16755 12cf25d5d8a4a0687bc4bafac0b24656 317 PRINTS PR00409 Phthalate dioxygenase reductase family signature 36 48 4.8E-46 T 14-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 LH59_16755 12cf25d5d8a4a0687bc4bafac0b24656 317 SUPERFAMILY SSF63380 2 93 1.43E-26 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel LH59_18110 10a517ac55e95d1bf97001ec91c50b1a 376 Pfam PF00842 Alanine racemase, C-terminal domain 250 371 1.8E-41 T 14-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LH59_18110 10a517ac55e95d1bf97001ec91c50b1a 376 SUPERFAMILY SSF50621 245 372 6.28E-45 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 LH59_18110 10a517ac55e95d1bf97001ec91c50b1a 376 Gene3D G3DSA:3.20.20.10 12 234 4.2E-106 T 14-10-2018 IPR029066 PLP-binding barrel LH59_18110 10a517ac55e95d1bf97001ec91c50b1a 376 Pfam PF01168 Alanine racemase, N-terminal domain 10 236 2.3E-61 T 14-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LH59_18110 10a517ac55e95d1bf97001ec91c50b1a 376 PRINTS PR00992 Alanine racemase signature 36 52 1.9E-60 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LH59_18110 10a517ac55e95d1bf97001ec91c50b1a 376 PRINTS PR00992 Alanine racemase signature 70 88 1.9E-60 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LH59_18110 10a517ac55e95d1bf97001ec91c50b1a 376 PRINTS PR00992 Alanine racemase signature 357 370 1.9E-60 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LH59_18110 10a517ac55e95d1bf97001ec91c50b1a 376 PRINTS PR00992 Alanine racemase signature 266 281 1.9E-60 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LH59_18110 10a517ac55e95d1bf97001ec91c50b1a 376 PRINTS PR00992 Alanine racemase signature 167 178 1.9E-60 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LH59_18110 10a517ac55e95d1bf97001ec91c50b1a 376 PRINTS PR00992 Alanine racemase signature 283 298 1.9E-60 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LH59_18110 10a517ac55e95d1bf97001ec91c50b1a 376 PRINTS PR00992 Alanine racemase signature 304 321 1.9E-60 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LH59_18110 10a517ac55e95d1bf97001ec91c50b1a 376 PRINTS PR00992 Alanine racemase signature 130 142 1.9E-60 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LH59_18110 10a517ac55e95d1bf97001ec91c50b1a 376 PRINTS PR00992 Alanine racemase signature 209 236 1.9E-60 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LH59_18110 10a517ac55e95d1bf97001ec91c50b1a 376 SUPERFAMILY SSF51419 9 251 8.07E-54 T 14-10-2018 IPR029066 PLP-binding barrel LH59_18110 10a517ac55e95d1bf97001ec91c50b1a 376 Gene3D G3DSA:2.40.37.10 235 370 4.2E-106 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 LH59_18110 10a517ac55e95d1bf97001ec91c50b1a 376 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 41 51 - T 14-10-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LH59_18110 10a517ac55e95d1bf97001ec91c50b1a 376 Hamap MF_01201 Alanine racemase. 2 375 32.79 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LH59_18110 10a517ac55e95d1bf97001ec91c50b1a 376 SMART SM01005 250 375 7.1E-64 T 14-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LH59_18110 10a517ac55e95d1bf97001ec91c50b1a 376 TIGRFAM TIGR00492 alr: alanine racemase 5 372 7.5E-100 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LH59_20480 182810523732a960df5824ef06686785 462 Pfam PF01425 Amidase 22 444 4.0E-92 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_20480 182810523732a960df5824ef06686785 462 Gene3D G3DSA:3.90.1300.10 4 454 4.1E-122 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_20480 182810523732a960df5824ef06686785 462 SUPERFAMILY SSF75304 5 453 7.33E-118 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_20480 182810523732a960df5824ef06686785 462 TIGRFAM TIGR02715 amido_AtzE: amidohydrolase, AtzE family 6 457 3.3E-193 T 14-10-2018 IPR014087 Amidohydrolase, AtzE type KEGG: 00791+3.5.1.84|MetaCyc: PWY-5169 LH59_04250 d2c0a7a9ec03cf3f940e3b67ab07bf39 220 SUPERFAMILY SSF51182 2 149 2.76E-11 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_04250 d2c0a7a9ec03cf3f940e3b67ab07bf39 220 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 185 200 7.8E-6 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 LH59_04250 d2c0a7a9ec03cf3f940e3b67ab07bf39 220 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 200 216 7.8E-6 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 LH59_04250 d2c0a7a9ec03cf3f940e3b67ab07bf39 220 Pfam PF12833 Helix-turn-helix domain 140 217 1.8E-23 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_04250 d2c0a7a9ec03cf3f940e3b67ab07bf39 220 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 171 212 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 LH59_04250 d2c0a7a9ec03cf3f940e3b67ab07bf39 220 SMART SM00342 134 216 2.3E-27 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_04250 d2c0a7a9ec03cf3f940e3b67ab07bf39 220 SUPERFAMILY SSF46689 171 216 9.86E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_04250 d2c0a7a9ec03cf3f940e3b67ab07bf39 220 Gene3D G3DSA:1.10.10.60 119 220 4.6E-22 T 14-10-2018 LH59_21870 af84d0e3de487b59c9973ac9adf209d5 451 ProSitePatterns PS00217 Sugar transport proteins signature 2. 118 143 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 LH59_21870 af84d0e3de487b59c9973ac9adf209d5 451 Gene3D G3DSA:1.20.1250.20 250 429 2.3E-21 T 14-10-2018 LH59_21870 af84d0e3de487b59c9973ac9adf209d5 451 SUPERFAMILY SSF103473 12 430 5.75E-74 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_21870 af84d0e3de487b59c9973ac9adf209d5 451 ProSitePatterns PS00216 Sugar transport proteins signature 1. 76 91 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 LH59_21870 af84d0e3de487b59c9973ac9adf209d5 451 Gene3D G3DSA:1.20.1250.20 12 220 1.4E-45 T 14-10-2018 LH59_21870 af84d0e3de487b59c9973ac9adf209d5 451 Pfam PF07690 Major Facilitator Superfamily 25 285 1.3E-34 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_21870 af84d0e3de487b59c9973ac9adf209d5 451 Pfam PF07690 Major Facilitator Superfamily 288 428 4.9E-12 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_00715 f5d73e30fd6656164b5b80f7e5428241 92 TIGRFAM TIGR02385 RelE_StbE: addiction module toxin, RelE/StbE family 4 84 1.6E-8 T 14-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family LH59_00715 f5d73e30fd6656164b5b80f7e5428241 92 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 4 90 1.6E-16 T 14-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family LH59_00715 f5d73e30fd6656164b5b80f7e5428241 92 Gene3D G3DSA:3.30.2310.20 1 91 6.9E-32 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily LH59_11675 ec00cc05380473a38665cca9c28758aa 399 Gene3D G3DSA:1.10.1740.10 313 397 1.6E-26 T 14-10-2018 LH59_11675 ec00cc05380473a38665cca9c28758aa 399 PIRSF PIRSF006205 4 398 7.1E-144 T 14-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 LH59_11675 ec00cc05380473a38665cca9c28758aa 399 Pfam PF13288 DXP reductoisomerase C-terminal domain 272 390 5.4E-39 T 14-10-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 LH59_11675 ec00cc05380473a38665cca9c28758aa 399 SUPERFAMILY SSF51735 5 153 5.71E-39 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_11675 ec00cc05380473a38665cca9c28758aa 399 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 7 396 44.984 T 14-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 LH59_11675 ec00cc05380473a38665cca9c28758aa 399 SUPERFAMILY SSF55347 129 275 4.9E-62 T 14-10-2018 LH59_11675 ec00cc05380473a38665cca9c28758aa 399 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 7 135 1.6E-39 T 14-10-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 LH59_11675 ec00cc05380473a38665cca9c28758aa 399 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 149 240 2.4E-38 T 14-10-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 LH59_11675 ec00cc05380473a38665cca9c28758aa 399 Gene3D G3DSA:3.40.50.720 2 153 9.5E-49 T 14-10-2018 LH59_11675 ec00cc05380473a38665cca9c28758aa 399 SUPERFAMILY SSF69055 303 395 6.41E-28 T 14-10-2018 IPR036169 DXP reductoisomerase, C-terminal domain superfamily KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 LH59_11675 ec00cc05380473a38665cca9c28758aa 399 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 5 391 1.7E-141 T 14-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 LH59_05270 16f36556fe798cac5dc9c8a3ebb527c1 178 Hamap MF_00925 Outer membrane protein assembly factor BamE [bamE]. 14 120 26.932 T 14-10-2018 IPR026592 Outer membrane protein assembly factor BamE LH59_05270 16f36556fe798cac5dc9c8a3ebb527c1 178 Pfam PF04355 SmpA / OmlA family 42 111 1.1E-24 T 14-10-2018 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 LH59_05270 16f36556fe798cac5dc9c8a3ebb527c1 178 Gene3D G3DSA:3.30.1450.10 48 122 2.2E-27 T 14-10-2018 IPR037873 BamE-like LH59_22085 4fa70de179dda77f9604a2892ba41d8d 887 Pfam PF12705 PD-(D/E)XK nuclease superfamily 608 872 9.9E-19 T 14-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type LH59_22085 4fa70de179dda77f9604a2892ba41d8d 887 SUPERFAMILY SSF52540 220 564 3.45E-19 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_22085 4fa70de179dda77f9604a2892ba41d8d 887 TIGRFAM TIGR03623 TIGR03623: probable DNA repair protein 25 880 5.0E-243 T 14-10-2018 IPR019925 DNA repair protein, predicted LH59_07620 455ede03d38496fd43fba9cc2dcdb713 591 Pfam PF00849 RNA pseudouridylate synthase 183 316 2.7E-15 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 LH59_07620 455ede03d38496fd43fba9cc2dcdb713 591 SUPERFAMILY SSF55174 121 212 1.28E-17 T 14-10-2018 LH59_07620 455ede03d38496fd43fba9cc2dcdb713 591 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 187 347 9.3E-50 T 14-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 LH59_07620 455ede03d38496fd43fba9cc2dcdb713 591 Gene3D G3DSA:3.30.70.580 184 343 2.7E-45 T 14-10-2018 LH59_07620 455ede03d38496fd43fba9cc2dcdb713 591 SMART SM00363 120 178 1.4E-10 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_07620 455ede03d38496fd43fba9cc2dcdb713 591 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 221 235 - T 14-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 LH59_07620 455ede03d38496fd43fba9cc2dcdb713 591 SUPERFAMILY SSF55120 182 346 8.64E-39 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 LH59_07620 455ede03d38496fd43fba9cc2dcdb713 591 Gene3D G3DSA:3.30.70.1560 245 335 2.7E-45 T 14-10-2018 LH59_07620 455ede03d38496fd43fba9cc2dcdb713 591 Gene3D G3DSA:3.10.290.10 119 173 4.5E-21 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 LH59_07620 455ede03d38496fd43fba9cc2dcdb713 591 Pfam PF01479 S4 domain 122 165 9.6E-10 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_14360 751b8ed20ffed19232245673276315ee 222 Gene3D G3DSA:3.40.50.150 7 222 7.9E-37 T 14-10-2018 LH59_14360 751b8ed20ffed19232245673276315ee 222 SUPERFAMILY SSF53335 10 221 1.93E-27 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_14360 751b8ed20ffed19232245673276315ee 222 Pfam PF13649 Methyltransferase domain 46 138 9.2E-14 T 14-10-2018 LH59_22680 b58acf29f75e5d5f01ea7f557f4c8e5d 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 285 3.1E-20 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_22680 b58acf29f75e5d5f01ea7f557f4c8e5d 291 SUPERFAMILY SSF161098 93 278 1.7E-28 T 14-10-2018 IPR035906 MetI-like superfamily LH59_22680 b58acf29f75e5d5f01ea7f557f4c8e5d 291 TIGRFAM TIGR01183 ntrB: nitrate ABC transporter, permease protein 83 279 6.8E-73 T 14-10-2018 IPR005889 Nitrate transport permease GO:0015112|GO:0015706|GO:0016021 LH59_22680 b58acf29f75e5d5f01ea7f557f4c8e5d 291 Gene3D G3DSA:1.10.3720.10 96 287 7.7E-24 T 14-10-2018 IPR035906 MetI-like superfamily LH59_16255 7d32502336763a7216e94231b8430b7b 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 8.4E-20 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_16255 7d32502336763a7216e94231b8430b7b 299 Gene3D G3DSA:3.40.190.10 93 281 6.6E-56 T 14-10-2018 LH59_16255 7d32502336763a7216e94231b8430b7b 299 Gene3D G3DSA:3.40.190.10 166 268 6.6E-56 T 14-10-2018 LH59_16255 7d32502336763a7216e94231b8430b7b 299 Gene3D G3DSA:1.10.10.10 3 91 1.4E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_16255 7d32502336763a7216e94231b8430b7b 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 8.7E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_16255 7d32502336763a7216e94231b8430b7b 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 8.7E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_16255 7d32502336763a7216e94231b8430b7b 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 8.7E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_16255 7d32502336763a7216e94231b8430b7b 299 SUPERFAMILY SSF46785 2 113 1.29E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_16255 7d32502336763a7216e94231b8430b7b 299 SUPERFAMILY SSF53850 91 295 1.23E-53 T 14-10-2018 LH59_16255 7d32502336763a7216e94231b8430b7b 299 Pfam PF03466 LysR substrate binding domain 89 293 1.2E-53 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_22635 6565ea0f53decbdc3becfe0d83e85e29 369 SUPERFAMILY SSF49401 288 369 1.09E-7 T 14-10-2018 IPR008966 Adhesion domain superfamily LH59_22635 6565ea0f53decbdc3becfe0d83e85e29 369 Gene3D G3DSA:2.60.40.1090 271 369 5.7E-5 T 14-10-2018 IPR036937 Fimbrial-type adhesion domain superfamily GO:0007155|GO:0009289 LH59_03395 dadb2e56d915501c9c466ededcec7b5d 469 Gene3D G3DSA:3.10.450.350 198 440 1.0E-94 T 14-10-2018 LH59_03395 dadb2e56d915501c9c466ededcec7b5d 469 Gene3D G3DSA:2.70.70.10 295 425 1.0E-94 T 14-10-2018 IPR011055 Duplicated hybrid motif LH59_03395 dadb2e56d915501c9c466ededcec7b5d 469 SUPERFAMILY SSF51261 170 421 4.76E-73 T 14-10-2018 IPR011055 Duplicated hybrid motif LH59_03395 dadb2e56d915501c9c466ededcec7b5d 469 Gene3D G3DSA:3.10.450.350 80 167 8.1E-18 T 14-10-2018 LH59_03395 dadb2e56d915501c9c466ededcec7b5d 469 Pfam PF01551 Peptidase family M23 323 419 3.8E-34 T 14-10-2018 IPR016047 Peptidase M23 LH59_17825 2b36eeaaa147acca60a890f261ea6b50 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 50 73 1.4E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_17825 2b36eeaaa147acca60a890f261ea6b50 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 42 1.4E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_17825 2b36eeaaa147acca60a890f261ea6b50 209 Gene3D G3DSA:1.10.357.10 19 206 2.8E-53 T 14-10-2018 LH59_17825 2b36eeaaa147acca60a890f261ea6b50 209 SUPERFAMILY SSF46689 22 91 5.13E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_17825 2b36eeaaa147acca60a890f261ea6b50 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 74 2.5E-14 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_17825 2b36eeaaa147acca60a890f261ea6b50 209 SUPERFAMILY SSF48498 97 201 3.25E-13 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily LH59_04235 bb6616d7da97e69a26494badaf53e85c 303 SUPERFAMILY SSF46785 5 114 8.16E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_04235 bb6616d7da97e69a26494badaf53e85c 303 SUPERFAMILY SSF53850 95 298 1.74E-39 T 14-10-2018 LH59_04235 bb6616d7da97e69a26494badaf53e85c 303 Gene3D G3DSA:3.40.190.290 97 301 1.1E-35 T 14-10-2018 LH59_04235 bb6616d7da97e69a26494badaf53e85c 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 67 6.5E-20 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_04235 bb6616d7da97e69a26494badaf53e85c 303 Gene3D G3DSA:1.10.10.10 6 94 1.0E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_04235 bb6616d7da97e69a26494badaf53e85c 303 Pfam PF03466 LysR substrate binding domain 95 297 3.2E-39 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_01645 7e0f81b45f317e0794b096f4b2a57060 260 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 251 1.3E-25 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_01645 7e0f81b45f317e0794b096f4b2a57060 260 Gene3D G3DSA:1.10.3720.10 54 252 4.6E-25 T 14-10-2018 IPR035906 MetI-like superfamily LH59_01645 7e0f81b45f317e0794b096f4b2a57060 260 SUPERFAMILY SSF161098 57 242 3.01E-33 T 14-10-2018 IPR035906 MetI-like superfamily LH59_17205 628d38c838217c1ce9abae2cb3066f19 679 Gene3D G3DSA:3.40.50.300 276 426 4.4E-51 T 14-10-2018 LH59_17205 628d38c838217c1ce9abae2cb3066f19 679 Gene3D G3DSA:3.40.50.300 9 246 4.8E-70 T 14-10-2018 LH59_17205 628d38c838217c1ce9abae2cb3066f19 679 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 18 670 0.0 T 14-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 LH59_17205 628d38c838217c1ce9abae2cb3066f19 679 Pfam PF00271 Helicase conserved C-terminal domain 453 556 4.0E-18 T 14-10-2018 IPR001650 Helicase, C-terminal LH59_17205 628d38c838217c1ce9abae2cb3066f19 679 Pfam PF04851 Type III restriction enzyme, res subunit 50 150 1.7E-8 T 14-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 LH59_17205 628d38c838217c1ce9abae2cb3066f19 679 Hamap MF_00204 UvrABC system protein B [uvrB]. 16 672 42.728 T 14-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 LH59_17205 628d38c838217c1ce9abae2cb3066f19 679 SUPERFAMILY SSF52540 17 427 2.7E-135 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_17205 628d38c838217c1ce9abae2cb3066f19 679 SUPERFAMILY SSF52540 50 594 7.77E-38 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_17205 628d38c838217c1ce9abae2cb3066f19 679 SMART SM00490 472 558 6.2E-20 T 14-10-2018 IPR001650 Helicase, C-terminal LH59_17205 628d38c838217c1ce9abae2cb3066f19 679 Pfam PF12344 Ultra-violet resistance protein B 564 606 7.4E-20 T 14-10-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain LH59_17205 628d38c838217c1ce9abae2cb3066f19 679 SUPERFAMILY SSF46600 634 672 1.24E-8 T 14-10-2018 IPR036876 UVR domain superfamily LH59_17205 628d38c838217c1ce9abae2cb3066f19 679 Pfam PF02151 UvrB/uvrC motif 638 671 1.7E-4 T 14-10-2018 IPR001943 UVR domain GO:0005515 LH59_17205 628d38c838217c1ce9abae2cb3066f19 679 Gene3D G3DSA:3.40.50.300 427 608 1.8E-49 T 14-10-2018 LH59_17205 628d38c838217c1ce9abae2cb3066f19 679 SMART SM00487 22 437 2.4E-28 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain LH59_17205 628d38c838217c1ce9abae2cb3066f19 679 Gene3D G3DSA:4.10.860.10 616 676 4.3E-17 T 14-10-2018 LH59_11935 bf01a3222a01a7df97d7464c5a293997 224 SUPERFAMILY SSF51569 33 197 6.23E-7 T 14-10-2018 LH59_27120 51a7105903e2f4cb12dcd12ce016f229 288 PIRSF PIRSF026649 1 280 2.1E-79 T 14-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 LH59_27120 51a7105903e2f4cb12dcd12ce016f229 288 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 4 271 1.3E-36 T 14-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 LH59_21880 e1fb1438ca6548e26cef89a32f6da411 285 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 22 283 1.4E-83 T 14-10-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 LH59_21880 e1fb1438ca6548e26cef89a32f6da411 285 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 281 4.1E-24 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_21880 e1fb1438ca6548e26cef89a32f6da411 285 Gene3D G3DSA:1.10.3720.10 69 285 5.1E-27 T 14-10-2018 IPR035906 MetI-like superfamily LH59_21880 e1fb1438ca6548e26cef89a32f6da411 285 SUPERFAMILY SSF161098 32 279 2.06E-35 T 14-10-2018 IPR035906 MetI-like superfamily LH59_22775 9db3827313043154659b93b93814d862 447 Pfam PF01938 TRAM domain 376 436 7.6E-15 T 14-10-2018 IPR002792 TRAM domain LH59_22775 9db3827313043154659b93b93814d862 447 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 2 434 2.5E-150 T 14-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 LH59_22775 9db3827313043154659b93b93814d862 447 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 147 167 - T 14-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 LH59_22775 9db3827313043154659b93b93814d862 447 Gene3D G3DSA:3.80.30.20 141 377 5.9E-84 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe LH59_22775 9db3827313043154659b93b93814d862 447 SUPERFAMILY SSF102114 125 369 1.31E-59 T 14-10-2018 LH59_22775 9db3827313043154659b93b93814d862 447 SMART SM00729 143 364 7.6E-57 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 LH59_22775 9db3827313043154659b93b93814d862 447 Pfam PF00919 Uncharacterized protein family UPF0004 2 100 9.9E-30 T 14-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 LH59_22775 9db3827313043154659b93b93814d862 447 Pfam PF04055 Radical SAM superfamily 147 322 3.7E-30 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 LH59_22775 9db3827313043154659b93b93814d862 447 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 1 436 8.0E-182 T 14-10-2018 LH59_22775 9db3827313043154659b93b93814d862 447 Gene3D G3DSA:3.40.50.12160 1 133 5.7E-34 T 14-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily LH59_22775 9db3827313043154659b93b93814d862 447 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 1 437 73.78 T 14-10-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 LH59_23260 d7e1ad08bccaadda8602a98adb56c9d1 157 Gene3D G3DSA:3.30.70.920 57 150 2.0E-19 T 14-10-2018 LH59_23260 d7e1ad08bccaadda8602a98adb56c9d1 157 Pfam PF13412 Winged helix-turn-helix DNA-binding 3 50 3.6E-16 T 14-10-2018 LH59_23260 d7e1ad08bccaadda8602a98adb56c9d1 157 Gene3D G3DSA:1.10.10.10 1 56 2.8E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_23260 d7e1ad08bccaadda8602a98adb56c9d1 157 SUPERFAMILY SSF46785 2 63 2.95E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_23260 d7e1ad08bccaadda8602a98adb56c9d1 157 Pfam PF01037 Lrp/AsnC ligand binding domain 69 142 9.3E-18 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LH59_23260 d7e1ad08bccaadda8602a98adb56c9d1 157 SMART SM00344 3 112 1.2E-35 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 LH59_23260 d7e1ad08bccaadda8602a98adb56c9d1 157 SUPERFAMILY SSF54909 63 148 4.29E-17 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel LH59_23260 d7e1ad08bccaadda8602a98adb56c9d1 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 8.1E-12 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_23260 d7e1ad08bccaadda8602a98adb56c9d1 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 8.1E-12 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_23260 d7e1ad08bccaadda8602a98adb56c9d1 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 8.1E-12 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_23260 d7e1ad08bccaadda8602a98adb56c9d1 157 ProSitePatterns PS00519 AsnC-type HTH domain signature. 21 47 - T 14-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site LH59_15180 172e7efbba3f0181ebedbcad1a4849e7 352 SUPERFAMILY SSF56601 45 331 1.07E-54 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like LH59_15180 172e7efbba3f0181ebedbcad1a4849e7 352 Pfam PF00144 Beta-lactamase 73 328 1.4E-18 T 14-10-2018 IPR001466 Beta-lactamase-related LH59_15180 172e7efbba3f0181ebedbcad1a4849e7 352 Gene3D G3DSA:3.40.710.10 40 339 2.8E-45 T 14-10-2018 LH59_07140 69f7f4d8890a479208d9d8a0c55de162 761 Pfam PF00005 ABC transporter 524 671 8.8E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_07140 69f7f4d8890a479208d9d8a0c55de162 761 SUPERFAMILY SSF90123 172 486 8.24E-77 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 LH59_07140 69f7f4d8890a479208d9d8a0c55de162 761 SUPERFAMILY SSF52540 496 741 2.46E-93 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_07140 69f7f4d8890a479208d9d8a0c55de162 761 ProSitePatterns PS00211 ABC transporters family signature. 643 657 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_07140 69f7f4d8890a479208d9d8a0c55de162 761 Pfam PF00664 ABC transporter transmembrane region 185 457 1.8E-43 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 LH59_07140 69f7f4d8890a479208d9d8a0c55de162 761 Gene3D G3DSA:3.40.50.300 499 757 4.1E-96 T 14-10-2018 LH59_07140 69f7f4d8890a479208d9d8a0c55de162 761 SMART SM00382 531 723 7.1E-19 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_07140 69f7f4d8890a479208d9d8a0c55de162 761 Gene3D G3DSA:1.20.1560.10 151 493 8.7E-87 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 LH59_17025 99f5d8ce4028a740988fda9f247406bf 318 SUPERFAMILY SSF53807 32 300 4.71E-62 T 14-10-2018 LH59_17025 99f5d8ce4028a740988fda9f247406bf 318 Gene3D G3DSA:3.40.50.12260 181 285 5.1E-90 T 14-10-2018 LH59_17025 99f5d8ce4028a740988fda9f247406bf 318 Pfam PF01497 Periplasmic binding protein 53 284 1.8E-24 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain LH59_17025 99f5d8ce4028a740988fda9f247406bf 318 Gene3D G3DSA:3.40.50.1980 44 299 5.1E-90 T 14-10-2018 LH59_17885 c4778df28a10a4a366fa7c84865242a6 710 Pfam PF00912 Transglycosylase 40 211 8.2E-46 T 14-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 LH59_17885 c4778df28a10a4a366fa7c84865242a6 710 Pfam PF00905 Penicillin binding protein transpeptidase domain 298 535 5.3E-16 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 LH59_17885 c4778df28a10a4a366fa7c84865242a6 710 Pfam PF06832 Penicillin-Binding Protein C-terminus Family 619 703 5.3E-17 T 14-10-2018 IPR009647 Penicillin-binding, C-terminal KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 LH59_17885 c4778df28a10a4a366fa7c84865242a6 710 SUPERFAMILY SSF56601 193 621 1.63E-94 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like LH59_17885 c4778df28a10a4a366fa7c84865242a6 710 SUPERFAMILY SSF53955 23 242 8.15E-61 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily LH59_17885 c4778df28a10a4a366fa7c84865242a6 710 Gene3D G3DSA:1.10.3810.10 34 227 2.9E-50 T 14-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 LH59_17885 c4778df28a10a4a366fa7c84865242a6 710 TIGRFAM TIGR02073 PBP_1c: penicillin-binding protein 1C 22 617 1.2E-228 T 14-10-2018 IPR011815 Penicillin-binding protein 1C GO:0008955|GO:0009252 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 LH59_17885 c4778df28a10a4a366fa7c84865242a6 710 Gene3D G3DSA:3.40.710.10 268 585 7.0E-69 T 14-10-2018 LH59_07805 e9171edc60e5905db4b5318649e024ef 304 Pfam PF05675 Protein of unknown function (DUF817) 38 274 3.3E-106 T 14-10-2018 IPR008535 Protein of unknown function DUF817 LH59_07805 e9171edc60e5905db4b5318649e024ef 304 PIRSF PIRSF009141 29 289 8.4E-101 T 14-10-2018 IPR008535 Protein of unknown function DUF817 LH59_19135 4ffe67e1cb737d2a42bb8c2962f5e752 794 SUPERFAMILY SSF56634 105 622 2.22E-218 T 14-10-2018 IPR020835 Catalase superfamily GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 LH59_19135 4ffe67e1cb737d2a42bb8c2962f5e752 794 SMART SM01060 125 513 2.7E-277 T 14-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 LH59_19135 4ffe67e1cb737d2a42bb8c2962f5e752 794 Pfam PF00199 Catalase 125 509 1.3E-179 T 14-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 LH59_19135 4ffe67e1cb737d2a42bb8c2962f5e752 794 SUPERFAMILY SSF52317 641 755 1.99E-21 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_19135 4ffe67e1cb737d2a42bb8c2962f5e752 794 Gene3D G3DSA:1.20.1370.20 537 638 4.1E-31 T 14-10-2018 LH59_19135 4ffe67e1cb737d2a42bb8c2962f5e752 794 PRINTS PR00067 Catalase signature 222 239 6.6E-70 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 LH59_19135 4ffe67e1cb737d2a42bb8c2962f5e752 794 PRINTS PR00067 Catalase signature 201 219 6.6E-70 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 LH59_19135 4ffe67e1cb737d2a42bb8c2962f5e752 794 PRINTS PR00067 Catalase signature 442 468 6.6E-70 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 LH59_19135 4ffe67e1cb737d2a42bb8c2962f5e752 794 PRINTS PR00067 Catalase signature 410 437 6.6E-70 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 LH59_19135 4ffe67e1cb737d2a42bb8c2962f5e752 794 PRINTS PR00067 Catalase signature 138 161 6.6E-70 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 LH59_19135 4ffe67e1cb737d2a42bb8c2962f5e752 794 PRINTS PR00067 Catalase signature 241 259 6.6E-70 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 LH59_19135 4ffe67e1cb737d2a42bb8c2962f5e752 794 Gene3D G3DSA:2.40.180.10 12 532 6.6E-207 T 14-10-2018 IPR037060 Catalase core domain superfamily GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 LH59_19135 4ffe67e1cb737d2a42bb8c2962f5e752 794 Pfam PF01965 DJ-1/PfpI family 642 753 7.8E-15 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 LH59_19135 4ffe67e1cb737d2a42bb8c2962f5e752 794 PIRSF PIRSF038927 89 793 0.0 T 14-10-2018 IPR024712 Catalase, mono-functional, haem-containing, clade 2 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 LH59_19135 4ffe67e1cb737d2a42bb8c2962f5e752 794 ProSitePatterns PS00438 Catalase proximal active site signature. 161 177 - T 14-10-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 LH59_19135 4ffe67e1cb737d2a42bb8c2962f5e752 794 Gene3D G3DSA:3.40.50.880 641 793 3.1E-35 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_19135 4ffe67e1cb737d2a42bb8c2962f5e752 794 Pfam PF06628 Catalase-related immune-responsive 539 602 5.1E-18 T 14-10-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 LH59_14385 2efe368ce840c1f01f0e40766cf314de 217 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 3.1E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_14385 2efe368ce840c1f01f0e40766cf314de 217 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 3.1E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_14385 2efe368ce840c1f01f0e40766cf314de 217 SMART SM00345 9 67 8.5E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_14385 2efe368ce840c1f01f0e40766cf314de 217 Gene3D G3DSA:1.10.10.10 3 68 3.8E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_14385 2efe368ce840c1f01f0e40766cf314de 217 Gene3D G3DSA:1.20.120.530 71 208 2.9E-27 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_14385 2efe368ce840c1f01f0e40766cf314de 217 SMART SM00895 77 197 7.0E-15 T 14-10-2018 IPR011711 GntR, C-terminal LH59_14385 2efe368ce840c1f01f0e40766cf314de 217 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 67 1.8E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_14385 2efe368ce840c1f01f0e40766cf314de 217 SUPERFAMILY SSF46785 4 71 8.51E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_14385 2efe368ce840c1f01f0e40766cf314de 217 Pfam PF07729 FCD domain 77 196 1.7E-21 T 14-10-2018 IPR011711 GntR, C-terminal LH59_14385 2efe368ce840c1f01f0e40766cf314de 217 SUPERFAMILY SSF48008 74 205 1.36E-21 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_15075 69d679fed3b3f5bb320899c2670186a6 202 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 3 194 4.8E-16 T 14-10-2018 IPR003111 Lon, substrate-binding domain LH59_15075 69d679fed3b3f5bb320899c2670186a6 202 SUPERFAMILY SSF88697 3 198 2.14E-46 T 14-10-2018 IPR015947 PUA-like superfamily LH59_15075 69d679fed3b3f5bb320899c2670186a6 202 SMART SM00464 3 199 6.5E-6 T 14-10-2018 IPR003111 Lon, substrate-binding domain LH59_15075 69d679fed3b3f5bb320899c2670186a6 202 Gene3D G3DSA:1.10.4060.10 115 201 2.3E-28 T 14-10-2018 LH59_15075 69d679fed3b3f5bb320899c2670186a6 202 Gene3D G3DSA:2.30.130.40 1 114 1.1E-38 T 14-10-2018 LH59_19080 e4c6d9c55589feffd5b53139ed1b12f0 892 Pfam PF12951 Passenger-associated-transport-repeat 379 409 2.6E-8 T 14-10-2018 IPR013425 Autotransporter-associated beta strand repeat LH59_19080 e4c6d9c55589feffd5b53139ed1b12f0 892 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 445 892 2.2E-108 T 14-10-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 LH59_19080 e4c6d9c55589feffd5b53139ed1b12f0 892 Gene3D G3DSA:2.160.20.20 417 560 6.4E-39 T 14-10-2018 IPR012332 P22 tailspike-like, C-terminal domain superfamily LH59_19080 e4c6d9c55589feffd5b53139ed1b12f0 892 Pfam PF03797 Autotransporter beta-domain 622 871 1.3E-43 T 14-10-2018 IPR005546 Autotransporter beta-domain LH59_19080 e4c6d9c55589feffd5b53139ed1b12f0 892 SUPERFAMILY SSF103515 587 892 4.45E-47 T 14-10-2018 IPR036709 Autotransporter beta-domain superfamily LH59_19080 e4c6d9c55589feffd5b53139ed1b12f0 892 Pfam PF03212 Pertactin 462 557 9.6E-7 T 14-10-2018 IPR004899 Pertactin, central region LH59_19080 e4c6d9c55589feffd5b53139ed1b12f0 892 Gene3D G3DSA:2.40.128.130 579 892 7.5E-73 T 14-10-2018 IPR036709 Autotransporter beta-domain superfamily LH59_19080 e4c6d9c55589feffd5b53139ed1b12f0 892 SUPERFAMILY SSF51126 53 559 2.29E-39 T 14-10-2018 IPR011050 Pectin lyase fold/virulence factor LH59_19080 e4c6d9c55589feffd5b53139ed1b12f0 892 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 380 410 1.8E-9 T 14-10-2018 IPR013425 Autotransporter-associated beta strand repeat LH59_19080 e4c6d9c55589feffd5b53139ed1b12f0 892 SMART SM00869 619 881 4.9E-43 T 14-10-2018 IPR005546 Autotransporter beta-domain LH59_19080 e4c6d9c55589feffd5b53139ed1b12f0 892 TIGRFAM TIGR04393 rpt_T5SS_PEPC: T5SS/PEP-CTERM-associated repeat 68 121 7.4E-6 T 14-10-2018 IPR030895 T5SS/PEP-CTERM-associated repeat LH59_19080 e4c6d9c55589feffd5b53139ed1b12f0 892 TIGRFAM TIGR04393 rpt_T5SS_PEPC: T5SS/PEP-CTERM-associated repeat 39 65 5.1E-6 T 14-10-2018 IPR030895 T5SS/PEP-CTERM-associated repeat LH59_19080 e4c6d9c55589feffd5b53139ed1b12f0 892 TIGRFAM TIGR04393 rpt_T5SS_PEPC: T5SS/PEP-CTERM-associated repeat 125 174 8.5E-13 T 14-10-2018 IPR030895 T5SS/PEP-CTERM-associated repeat LH59_19080 e4c6d9c55589feffd5b53139ed1b12f0 892 TIGRFAM TIGR04393 rpt_T5SS_PEPC: T5SS/PEP-CTERM-associated repeat 236 283 2.6E-8 T 14-10-2018 IPR030895 T5SS/PEP-CTERM-associated repeat LH59_19080 e4c6d9c55589feffd5b53139ed1b12f0 892 TIGRFAM TIGR04393 rpt_T5SS_PEPC: T5SS/PEP-CTERM-associated repeat 176 223 2.1E-15 T 14-10-2018 IPR030895 T5SS/PEP-CTERM-associated repeat LH59_27115 c6a58fd6cbe0137c6510d92a804bedbb 387 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 120 130 - T 14-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 LH59_27115 c6a58fd6cbe0137c6510d92a804bedbb 387 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 263 271 - T 14-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 LH59_27115 c6a58fd6cbe0137c6510d92a804bedbb 387 Gene3D G3DSA:3.30.300.10 7 237 2.3E-176 T 14-10-2018 LH59_27115 c6a58fd6cbe0137c6510d92a804bedbb 387 SUPERFAMILY SSF55973 5 112 2.04E-45 T 14-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 LH59_27115 c6a58fd6cbe0137c6510d92a804bedbb 387 SUPERFAMILY SSF55973 237 385 3.26E-67 T 14-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 LH59_27115 c6a58fd6cbe0137c6510d92a804bedbb 387 Gene3D G3DSA:3.30.300.10 104 379 2.3E-176 T 14-10-2018 LH59_27115 c6a58fd6cbe0137c6510d92a804bedbb 387 PIRSF PIRSF000497 1 387 2.1E-170 T 14-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 LH59_27115 c6a58fd6cbe0137c6510d92a804bedbb 387 Pfam PF02772 S-adenosylmethionine synthetase, central domain 119 235 1.5E-45 T 14-10-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 LH59_27115 c6a58fd6cbe0137c6510d92a804bedbb 387 Gene3D G3DSA:3.30.300.10 13 274 2.3E-176 T 14-10-2018 LH59_27115 c6a58fd6cbe0137c6510d92a804bedbb 387 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 4 387 56.661 T 14-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 LH59_27115 c6a58fd6cbe0137c6510d92a804bedbb 387 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 7 385 6.8E-182 T 14-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 LH59_27115 c6a58fd6cbe0137c6510d92a804bedbb 387 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 6 103 4.1E-40 T 14-10-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 LH59_27115 c6a58fd6cbe0137c6510d92a804bedbb 387 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 237 375 1.2E-67 T 14-10-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 LH59_27115 c6a58fd6cbe0137c6510d92a804bedbb 387 SUPERFAMILY SSF55973 114 236 2.28E-52 T 14-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 LH59_12195 d9fe0c3ed1e076960ccc80c0765418b8 74 Pfam PF13275 S4 domain 13 71 5.1E-20 T 14-10-2018 LH59_12195 d9fe0c3ed1e076960ccc80c0765418b8 74 SUPERFAMILY SSF55174 6 72 5.63E-16 T 14-10-2018 LH59_12195 d9fe0c3ed1e076960ccc80c0765418b8 74 Gene3D G3DSA:3.10.290.10 2 73 2.1E-20 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 LH59_10485 ddc1688fa48da86e3e29913a5b2adc61 173 TIGRFAM TIGR00385 dsbE: periplasmic protein thiol:disulfide oxidoreductases, DsbE subfamily 5 170 1.5E-53 T 14-10-2018 IPR004799 Periplasmic protein thiol:disulphide oxidoreductase DsbE GO:0015036|GO:0017004|GO:0030288 LH59_10485 ddc1688fa48da86e3e29913a5b2adc61 173 Pfam PF00578 AhpC/TSA family 35 150 4.7E-17 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 LH59_10485 ddc1688fa48da86e3e29913a5b2adc61 173 ProSitePatterns PS00194 Thioredoxin family active site. 64 82 - T 14-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 LH59_10485 ddc1688fa48da86e3e29913a5b2adc61 173 Gene3D G3DSA:3.40.30.10 19 173 5.1E-41 T 14-10-2018 LH59_10485 ddc1688fa48da86e3e29913a5b2adc61 173 SUPERFAMILY SSF52833 47 171 1.36E-36 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_01885 bbde49bbcc5e063a81e7cd8c70eecaae 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 52 67 3.1E-10 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_01885 bbde49bbcc5e063a81e7cd8c70eecaae 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 210 224 3.1E-10 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_01885 bbde49bbcc5e063a81e7cd8c70eecaae 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 110 123 3.1E-10 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_01885 bbde49bbcc5e063a81e7cd8c70eecaae 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 96 109 3.1E-10 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_01885 bbde49bbcc5e063a81e7cd8c70eecaae 266 SUPERFAMILY SSF53474 7 263 1.16E-58 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_01885 bbde49bbcc5e063a81e7cd8c70eecaae 266 Gene3D G3DSA:3.40.50.1820 2 263 1.1E-74 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_01885 bbde49bbcc5e063a81e7cd8c70eecaae 266 TIGRFAM TIGR02427 protocat_pcaD: 3-oxoadipate enol-lactonase 16 263 2.2E-77 T 14-10-2018 IPR026968 3-oxoadipate enol-lactonase 1/2 GO:0042952|GO:0047570 KEGG: 00362+3.1.1.24|MetaCyc: PWY-6185 LH59_01885 bbde49bbcc5e063a81e7cd8c70eecaae 266 Pfam PF00561 alpha/beta hydrolase fold 36 138 1.2E-16 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_14905 8cfb80a82e3c08c433fa6ce6a1938488 252 SMART SM00346 5 95 3.6E-4 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_14905 8cfb80a82e3c08c433fa6ce6a1938488 252 Gene3D G3DSA:3.30.450.40 80 249 2.7E-51 T 14-10-2018 IPR029016 GAF-like domain superfamily LH59_14905 8cfb80a82e3c08c433fa6ce6a1938488 252 SUPERFAMILY SSF46785 8 73 1.29E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_14905 8cfb80a82e3c08c433fa6ce6a1938488 252 Pfam PF09339 IclR helix-turn-helix domain 8 57 2.5E-10 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_14905 8cfb80a82e3c08c433fa6ce6a1938488 252 SUPERFAMILY SSF55781 80 244 4.12E-47 T 14-10-2018 LH59_14905 8cfb80a82e3c08c433fa6ce6a1938488 252 Pfam PF01614 Bacterial transcriptional regulator 124 244 1.2E-28 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal LH59_14905 8cfb80a82e3c08c433fa6ce6a1938488 252 Gene3D G3DSA:1.10.10.10 4 77 2.2E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_27760 b3330c3bab0b36db9cb2d9739ca9e3ff 61 SUPERFAMILY SSF55129 4 60 1.7E-20 T 14-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily LH59_27760 b3330c3bab0b36db9cb2d9739ca9e3ff 61 Gene3D G3DSA:3.30.1390.20 2 60 6.3E-25 T 14-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily LH59_27760 b3330c3bab0b36db9cb2d9739ca9e3ff 61 PIRSF PIRSF002211 1 61 4.1E-27 T 14-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_27760 b3330c3bab0b36db9cb2d9739ca9e3ff 61 Pfam PF00327 Ribosomal protein L30p/L7e 6 56 2.6E-18 T 14-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain LH59_27760 b3330c3bab0b36db9cb2d9739ca9e3ff 61 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 6 60 1.0E-24 T 14-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_27760 b3330c3bab0b36db9cb2d9739ca9e3ff 61 ProSitePatterns PS00634 Ribosomal protein L30 signature. 24 56 - T 14-10-2018 IPR018038 Ribosomal protein L30, conserved site LH59_27760 b3330c3bab0b36db9cb2d9739ca9e3ff 61 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 2 60 20.263 T 14-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_05530 accdcf2045fa32b3cd6feba2d0bcc23b 446 Pfam PF16193 AAA C-terminal domain 191 268 6.3E-22 T 14-10-2018 IPR032423 AAA C-terminal domain LH59_05530 accdcf2045fa32b3cd6feba2d0bcc23b 446 SMART SM00382 51 167 6.5E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_05530 accdcf2045fa32b3cd6feba2d0bcc23b 446 Gene3D G3DSA:3.40.50.300 6 166 1.4E-41 T 14-10-2018 LH59_05530 accdcf2045fa32b3cd6feba2d0bcc23b 446 Gene3D G3DSA:1.10.3710.10 347 446 3.4E-36 T 14-10-2018 LH59_05530 accdcf2045fa32b3cd6feba2d0bcc23b 446 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 19 132 2.0E-12 T 14-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 LH59_05530 accdcf2045fa32b3cd6feba2d0bcc23b 446 Pfam PF12002 MgsA AAA+ ATPase C terminal 269 432 1.3E-67 T 14-10-2018 IPR021886 MgsA AAA+ ATPase C-terminal LH59_05530 accdcf2045fa32b3cd6feba2d0bcc23b 446 SUPERFAMILY SSF48019 253 434 9.07E-73 T 14-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 LH59_05530 accdcf2045fa32b3cd6feba2d0bcc23b 446 Gene3D G3DSA:1.20.272.10 243 346 7.2E-42 T 14-10-2018 LH59_05530 accdcf2045fa32b3cd6feba2d0bcc23b 446 Gene3D G3DSA:1.10.8.60 167 240 5.6E-7 T 14-10-2018 LH59_05530 accdcf2045fa32b3cd6feba2d0bcc23b 446 SUPERFAMILY SSF52540 13 237 7.13E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_11045 f70408bfca113912420a467b74a2c2cf 475 Gene3D G3DSA:3.30.450.90 76 212 4.6E-51 T 14-10-2018 LH59_11045 f70408bfca113912420a467b74a2c2cf 475 TIGRFAM TIGR02533 type_II_gspE: type II secretion system protein E 5 472 5.8E-214 T 14-10-2018 IPR013369 Type II secretion system GspE GO:0005524|GO:0008565|GO:0015627|GO:0015628 LH59_11045 f70408bfca113912420a467b74a2c2cf 475 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 307 321 - T 14-10-2018 IPR001482 Type II/IV secretion system protein LH59_11045 f70408bfca113912420a467b74a2c2cf 475 SUPERFAMILY SSF52540 91 472 3.28E-104 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_11045 f70408bfca113912420a467b74a2c2cf 475 SUPERFAMILY SSF160246 4 66 4.97E-8 T 14-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily LH59_11045 f70408bfca113912420a467b74a2c2cf 475 SMART SM00382 240 366 1.0E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_11045 f70408bfca113912420a467b74a2c2cf 475 Gene3D G3DSA:3.40.50.300 213 475 1.6E-112 T 14-10-2018 LH59_11045 f70408bfca113912420a467b74a2c2cf 475 Pfam PF00437 Type II/IV secretion system protein 117 379 2.6E-86 T 14-10-2018 IPR001482 Type II/IV secretion system protein LH59_14290 738185655929e13e622b9a26466fc7d2 286 SUPERFAMILY SSF53850 31 257 2.01E-40 T 14-10-2018 LH59_14290 738185655929e13e622b9a26466fc7d2 286 Gene3D G3DSA:3.40.190.10 124 218 3.3E-43 T 14-10-2018 LH59_14290 738185655929e13e622b9a26466fc7d2 286 SMART SM00062 35 260 7.8E-33 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_14290 738185655929e13e622b9a26466fc7d2 286 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 36 251 3.5E-35 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_14290 738185655929e13e622b9a26466fc7d2 286 Gene3D G3DSA:3.40.190.10 27 248 3.3E-43 T 14-10-2018 LH59_19600 c2037c7b19046eb825b742ef09968f55 328 SUPERFAMILY SSF52518 26 188 5.11E-48 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold LH59_19600 c2037c7b19046eb825b742ef09968f55 328 Pfam PF02780 Transketolase, C-terminal domain 197 318 1.7E-27 T 14-10-2018 IPR033248 Transketolase, C-terminal domain LH59_19600 c2037c7b19046eb825b742ef09968f55 328 SMART SM00861 21 186 2.5E-40 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain LH59_19600 c2037c7b19046eb825b742ef09968f55 328 Pfam PF02779 Transketolase, pyrimidine binding domain 27 181 6.1E-34 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain LH59_19600 c2037c7b19046eb825b742ef09968f55 328 Gene3D G3DSA:3.40.50.970 24 196 2.1E-52 T 14-10-2018 LH59_19600 c2037c7b19046eb825b742ef09968f55 328 Gene3D G3DSA:3.40.50.920 197 328 4.6E-35 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 LH59_19600 c2037c7b19046eb825b742ef09968f55 328 SUPERFAMILY SSF52922 193 326 1.16E-31 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 LH59_09845 d3b6dec573f59eca76da7f2972ab7514 491 Pfam PF00034 Cytochrome c 223 327 8.5E-6 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_09845 d3b6dec573f59eca76da7f2972ab7514 491 SUPERFAMILY SSF46626 199 331 7.4E-11 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_09845 d3b6dec573f59eca76da7f2972ab7514 491 Gene3D G3DSA:1.10.760.10 211 335 2.3E-11 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_03505 be8ec5a2c2c2e61baa76325ebadcacc4 492 Gene3D G3DSA:3.30.590.20 371 482 3.5E-8 T 14-10-2018 LH59_03505 be8ec5a2c2c2e61baa76325ebadcacc4 492 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 166 213 1.0E-9 T 14-10-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 LH59_03505 be8ec5a2c2c2e61baa76325ebadcacc4 492 SUPERFAMILY SSF55931 6 484 3.63E-17 T 14-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 LH59_03505 be8ec5a2c2c2e61baa76325ebadcacc4 492 Gene3D G3DSA:3.30.590.20 2 251 1.1E-17 T 14-10-2018 LH59_27270 015449f217a2a681fd98847cbf6832af 284 Gene3D G3DSA:2.30.30.100 235 284 2.2E-11 T 14-10-2018 LH59_27270 015449f217a2a681fd98847cbf6832af 284 SUPERFAMILY SSF55681 30 230 1.86E-35 T 14-10-2018 LH59_27270 015449f217a2a681fd98847cbf6832af 284 Pfam PF03099 Biotin/lipoate A/B protein ligase family 64 166 4.4E-9 T 14-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 LH59_27270 015449f217a2a681fd98847cbf6832af 284 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 34 280 6.6E-32 T 14-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LH59_27270 015449f217a2a681fd98847cbf6832af 284 SUPERFAMILY SSF50037 236 281 1.83E-6 T 14-10-2018 IPR008988 Transcriptional repressor, C-terminal LH59_27270 015449f217a2a681fd98847cbf6832af 284 Pfam PF02237 Biotin protein ligase C terminal domain 236 281 1.7E-7 T 14-10-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LH59_27270 015449f217a2a681fd98847cbf6832af 284 Gene3D G3DSA:3.30.930.10 20 233 4.6E-41 T 14-10-2018 LH59_01470 3a4933029442cdb29a29017597e534eb 540 SMART SM00283 270 517 6.7E-87 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 LH59_01470 3a4933029442cdb29a29017597e534eb 540 SUPERFAMILY SSF58104 237 520 2.75E-70 T 14-10-2018 LH59_01470 3a4933029442cdb29a29017597e534eb 540 SUPERFAMILY SSF47170 35 180 5.49E-6 T 14-10-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain superfamily LH59_01470 3a4933029442cdb29a29017597e534eb 540 Pfam PF02203 Tar ligand binding domain homologue 5 167 1.9E-12 T 14-10-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 LH59_01470 3a4933029442cdb29a29017597e534eb 540 SMART SM00304 217 269 2.3E-6 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_01470 3a4933029442cdb29a29017597e534eb 540 Gene3D G3DSA:1.10.287.950 217 519 4.6E-87 T 14-10-2018 LH59_01470 3a4933029442cdb29a29017597e534eb 540 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 329 485 4.2E-48 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 LH59_01470 3a4933029442cdb29a29017597e534eb 540 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 49 64 5.3E-52 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_01470 3a4933029442cdb29a29017597e534eb 540 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 291 320 5.3E-52 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_01470 3a4933029442cdb29a29017597e534eb 540 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 397 426 5.3E-52 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_01470 3a4933029442cdb29a29017597e534eb 540 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 368 395 5.3E-52 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_01470 3a4933029442cdb29a29017597e534eb 540 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 445 474 5.3E-52 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_22990 7401847547f4c0c51db64f449fb1e35c 220 SMART SM00862 145 216 2.8E-27 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_22990 7401847547f4c0c51db64f449fb1e35c 220 Gene3D G3DSA:3.40.50.2300 1 122 2.6E-42 T 14-10-2018 LH59_22990 7401847547f4c0c51db64f449fb1e35c 220 Pfam PF00072 Response regulator receiver domain 3 113 1.8E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_22990 7401847547f4c0c51db64f449fb1e35c 220 Gene3D G3DSA:1.10.10.10 123 219 1.4E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_22990 7401847547f4c0c51db64f449fb1e35c 220 SUPERFAMILY SSF52172 1 174 1.18E-41 T 14-10-2018 IPR011006 CheY-like superfamily LH59_22990 7401847547f4c0c51db64f449fb1e35c 220 SMART SM00448 1 112 2.9E-42 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_22990 7401847547f4c0c51db64f449fb1e35c 220 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 216 2.1E-25 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_14055 6f9e089b940c4fe173a90e7942f05023 742 TIGRFAM TIGR00178 monomer_idh: isocitrate dehydrogenase, NADP-dependent 4 740 0.0 T 14-10-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 LH59_14055 6f9e089b940c4fe173a90e7942f05023 742 Gene3D G3DSA:3.40.718.10 131 291 2.8E-5 T 14-10-2018 LH59_14055 6f9e089b940c4fe173a90e7942f05023 742 PIRSF PIRSF009407 1 742 0.0 T 14-10-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 LH59_14055 6f9e089b940c4fe173a90e7942f05023 742 SUPERFAMILY SSF53659 4 740 0.0 T 14-10-2018 LH59_14055 6f9e089b940c4fe173a90e7942f05023 742 Pfam PF03971 Monomeric isocitrate dehydrogenase 6 738 0.0 T 14-10-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 LH59_11460 0f80f247d5a5175a1c3614b686362085 577 SUPERFAMILY SSF47170 55 216 3.4E-9 T 14-10-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain superfamily LH59_11460 0f80f247d5a5175a1c3614b686362085 577 SMART SM00304 251 303 1.5E-13 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_11460 0f80f247d5a5175a1c3614b686362085 577 Pfam PF02203 Tar ligand binding domain homologue 34 188 9.7E-17 T 14-10-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 LH59_11460 0f80f247d5a5175a1c3614b686362085 577 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 363 520 2.4E-51 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 LH59_11460 0f80f247d5a5175a1c3614b686362085 577 SUPERFAMILY SSF58104 271 557 1.14E-71 T 14-10-2018 LH59_11460 0f80f247d5a5175a1c3614b686362085 577 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 325 354 9.3E-51 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_11460 0f80f247d5a5175a1c3614b686362085 577 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 89 104 9.3E-51 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_11460 0f80f247d5a5175a1c3614b686362085 577 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 34 59 9.3E-51 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_11460 0f80f247d5a5175a1c3614b686362085 577 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 480 509 9.3E-51 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_11460 0f80f247d5a5175a1c3614b686362085 577 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 432 461 9.3E-51 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_11460 0f80f247d5a5175a1c3614b686362085 577 Pfam PF00672 HAMP domain 251 299 6.3E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_11460 0f80f247d5a5175a1c3614b686362085 577 Gene3D G3DSA:1.10.287.950 251 554 9.4E-90 T 14-10-2018 LH59_11460 0f80f247d5a5175a1c3614b686362085 577 Gene3D G3DSA:1.20.120.30 52 230 2.8E-5 T 14-10-2018 LH59_11460 0f80f247d5a5175a1c3614b686362085 577 SMART SM00283 304 552 1.8E-87 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 LH59_07265 92f82b98a1c4735186823108fbcdf036 376 SUPERFAMILY SSF53383 4 375 2.04E-104 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_07265 92f82b98a1c4735186823108fbcdf036 376 Pfam PF00266 Aminotransferase class-V 5 363 2.6E-44 T 14-10-2018 IPR000192 Aminotransferase class V domain LH59_07265 92f82b98a1c4735186823108fbcdf036 376 PIRSF PIRSF000525 1 376 5.6E-137 T 14-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 LH59_07265 92f82b98a1c4735186823108fbcdf036 376 Gene3D G3DSA:3.40.640.10 17 273 3.8E-84 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_07265 92f82b98a1c4735186823108fbcdf036 376 Gene3D G3DSA:3.90.1150.10 274 376 2.1E-38 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_07265 92f82b98a1c4735186823108fbcdf036 376 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 2 375 47.765 T 14-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 LH59_07265 92f82b98a1c4735186823108fbcdf036 376 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 5 375 7.7E-138 T 14-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 LH59_07265 92f82b98a1c4735186823108fbcdf036 376 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 203 222 - T 14-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site LH59_25180 9e848270be0470daef6eca8b04797425 433 PRINTS PR00344 Bacterial sensor protein C-terminal signature 374 384 7.6E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_25180 9e848270be0470daef6eca8b04797425 433 PRINTS PR00344 Bacterial sensor protein C-terminal signature 391 409 7.6E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_25180 9e848270be0470daef6eca8b04797425 433 PRINTS PR00344 Bacterial sensor protein C-terminal signature 356 370 7.6E-11 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_25180 9e848270be0470daef6eca8b04797425 433 Gene3D G3DSA:3.30.565.10 277 429 9.9E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_25180 9e848270be0470daef6eca8b04797425 433 SUPERFAMILY SSF47384 194 273 1.57E-14 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 LH59_25180 9e848270be0470daef6eca8b04797425 433 Gene3D G3DSA:1.10.287.130 160 275 1.0E-23 T 14-10-2018 LH59_25180 9e848270be0470daef6eca8b04797425 433 SUPERFAMILY SSF55874 265 427 4.9E-36 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_25180 9e848270be0470daef6eca8b04797425 433 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 326 426 5.0E-19 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_25180 9e848270be0470daef6eca8b04797425 433 SMART SM00304 156 208 6.6E-6 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_25180 9e848270be0470daef6eca8b04797425 433 SMART SM00387 320 431 2.4E-27 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_25180 9e848270be0470daef6eca8b04797425 433 Pfam PF00512 His Kinase A (phospho-acceptor) domain 211 273 1.1E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_25180 9e848270be0470daef6eca8b04797425 433 SMART SM00388 209 274 6.2E-12 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_04535 5e6988b2c041aabd0864de080b63c4be 276 Gene3D G3DSA:3.10.129.10 36 152 1.2E-9 T 14-10-2018 LH59_04535 5e6988b2c041aabd0864de080b63c4be 276 SUPERFAMILY SSF54637 53 145 5.28E-7 T 14-10-2018 IPR029069 HotDog domain superfamily LH59_04535 5e6988b2c041aabd0864de080b63c4be 276 Pfam PF13452 N-terminal half of MaoC dehydratase 74 135 2.3E-7 T 14-10-2018 IPR039569 N-terminal of MaoC-like dehydratase Reactome: R-HSA-193368|Reactome: R-HSA-2046106|Reactome: R-HSA-389887|Reactome: R-HSA-390247|Reactome: R-HSA-9033241|Reactome: R-HSA-9033500 LH59_04535 5e6988b2c041aabd0864de080b63c4be 276 Gene3D G3DSA:3.10.129.10 160 275 5.1E-11 T 14-10-2018 LH59_04535 5e6988b2c041aabd0864de080b63c4be 276 SUPERFAMILY SSF54637 162 274 9.59E-15 T 14-10-2018 IPR029069 HotDog domain superfamily LH59_12975 b51eb5abc16bac02c7fee72fad49ffaf 326 PIRSF PIRSF017082 1 324 3.2E-89 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_12975 b51eb5abc16bac02c7fee72fad49ffaf 326 Gene3D G3DSA:3.40.190.150 29 315 1.4E-109 T 14-10-2018 LH59_12975 b51eb5abc16bac02c7fee72fad49ffaf 326 SUPERFAMILY SSF53850 113 284 1.22E-16 T 14-10-2018 LH59_12975 b51eb5abc16bac02c7fee72fad49ffaf 326 Gene3D G3DSA:3.40.190.10 127 250 1.4E-109 T 14-10-2018 LH59_12975 b51eb5abc16bac02c7fee72fad49ffaf 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 321 1.1E-85 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_17015 cdf8526e3e1018418d15a243668fe791 309 SUPERFAMILY SSF81345 4 306 2.62E-53 T 14-10-2018 IPR037294 ABC transporter, BtuC-like LH59_17015 cdf8526e3e1018418d15a243668fe791 309 Pfam PF01032 FecCD transport family 20 305 1.3E-51 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 LH59_17015 cdf8526e3e1018418d15a243668fe791 309 Gene3D G3DSA:1.10.3470.10 1 309 4.5E-52 T 14-10-2018 IPR037294 ABC transporter, BtuC-like LH59_15360 1a052470a2645c6203b4b0f5745c3550 408 SMART SM00860 32 204 0.0016 T 14-10-2018 IPR018958 Knr4/Smi1-like domain LH59_17370 d4bdf69bb268c024e6ddc8dce9160249 485 Pfam PF07690 Major Facilitator Superfamily 37 370 7.3E-26 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_17370 d4bdf69bb268c024e6ddc8dce9160249 485 Gene3D G3DSA:1.20.1250.20 27 448 1.2E-55 T 14-10-2018 LH59_17370 d4bdf69bb268c024e6ddc8dce9160249 485 SUPERFAMILY SSF103473 27 451 5.23E-53 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_00480 18186eeab7838f15c9bf15d2001cb2d9 809 Pfam PF00593 TonB dependent receptor 366 807 1.2E-54 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_00480 18186eeab7838f15c9bf15d2001cb2d9 809 SUPERFAMILY SSF56935 121 809 3.92E-127 T 14-10-2018 LH59_00480 18186eeab7838f15c9bf15d2001cb2d9 809 Gene3D G3DSA:2.40.170.20 273 809 5.4E-164 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_00480 18186eeab7838f15c9bf15d2001cb2d9 809 Gene3D G3DSA:3.55.50.30 37 140 2.6E-25 T 14-10-2018 LH59_00480 18186eeab7838f15c9bf15d2001cb2d9 809 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 165 806 9.9E-119 T 14-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 LH59_00480 18186eeab7838f15c9bf15d2001cb2d9 809 Pfam PF07660 Secretin and TonB N terminus short domain 68 117 1.3E-8 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 LH59_00480 18186eeab7838f15c9bf15d2001cb2d9 809 Pfam PF07715 TonB-dependent Receptor Plug Domain 162 265 9.6E-16 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_00480 18186eeab7838f15c9bf15d2001cb2d9 809 Gene3D G3DSA:2.170.130.10 141 272 1.6E-36 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily LH59_00480 18186eeab7838f15c9bf15d2001cb2d9 809 SMART SM00965 68 118 1.1E-12 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 LH59_11645 a026b3d6167e571ae14ff10c2f7047ff 249 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 4 15 - T 14-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 LH59_11645 a026b3d6167e571ae14ff10c2f7047ff 249 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 223 38.491 T 14-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_11645 a026b3d6167e571ae14ff10c2f7047ff 249 Gene3D G3DSA:1.10.287.610 101 148 6.9E-86 T 14-10-2018 LH59_11645 a026b3d6167e571ae14ff10c2f7047ff 249 Gene3D G3DSA:3.40.50.10490 6 217 6.9E-86 T 14-10-2018 LH59_11645 a026b3d6167e571ae14ff10c2f7047ff 249 PRINTS PR00395 Ribosomal protein S2 signature 156 173 4.9E-35 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_11645 a026b3d6167e571ae14ff10c2f7047ff 249 PRINTS PR00395 Ribosomal protein S2 signature 35 44 4.9E-35 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_11645 a026b3d6167e571ae14ff10c2f7047ff 249 PRINTS PR00395 Ribosomal protein S2 signature 173 184 4.9E-35 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_11645 a026b3d6167e571ae14ff10c2f7047ff 249 PRINTS PR00395 Ribosomal protein S2 signature 85 102 4.9E-35 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_11645 a026b3d6167e571ae14ff10c2f7047ff 249 PRINTS PR00395 Ribosomal protein S2 signature 194 208 4.9E-35 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_11645 a026b3d6167e571ae14ff10c2f7047ff 249 PRINTS PR00395 Ribosomal protein S2 signature 4 22 4.9E-35 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_11645 a026b3d6167e571ae14ff10c2f7047ff 249 SUPERFAMILY SSF52313 4 228 3.01E-90 T 14-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily LH59_11645 a026b3d6167e571ae14ff10c2f7047ff 249 Pfam PF00318 Ribosomal protein S2 7 222 3.8E-90 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_11645 a026b3d6167e571ae14ff10c2f7047ff 249 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 4 224 3.4E-97 T 14-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_06510 a892271b42322c69dd77fad38fe8ef6f 79 Gene3D G3DSA:1.10.1200.10 1 79 1.8E-30 T 14-10-2018 IPR036736 ACP-like superfamily LH59_06510 a892271b42322c69dd77fad38fe8ef6f 79 Pfam PF00550 Phosphopantetheine attachment site 6 73 1.7E-17 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain LH59_06510 a892271b42322c69dd77fad38fe8ef6f 79 SUPERFAMILY SSF47336 2 76 1.44E-23 T 14-10-2018 IPR036736 ACP-like superfamily LH59_06510 a892271b42322c69dd77fad38fe8ef6f 79 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site LH59_06510 a892271b42322c69dd77fad38fe8ef6f 79 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 41 76 0.004 T 14-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 LH59_06510 a892271b42322c69dd77fad38fe8ef6f 79 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 22.547 T 14-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 LH59_06510 a892271b42322c69dd77fad38fe8ef6f 79 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 2 76 1.7E-35 T 14-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 LH59_16940 db6eebed9df1c76d396ed9a699295d9a 222 SUPERFAMILY SSF88946 18 105 2.35E-6 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 LH59_16940 db6eebed9df1c76d396ed9a699295d9a 222 Gene3D G3DSA:1.10.10.10 115 191 6.0E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_16940 db6eebed9df1c76d396ed9a699295d9a 222 SUPERFAMILY SSF88659 105 189 1.07E-15 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like LH59_16940 db6eebed9df1c76d396ed9a699295d9a 222 Pfam PF08281 Sigma-70, region 4 134 184 1.0E-15 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LH59_16940 db6eebed9df1c76d396ed9a699295d9a 222 Pfam PF04542 Sigma-70 region 2 35 95 9.4E-7 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 LH59_16940 db6eebed9df1c76d396ed9a699295d9a 222 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 35 187 8.8E-21 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 LH59_08740 971b657c0ae1bf09cde044e2842449c9 251 Pfam PF00535 Glycosyl transferase family 2 4 121 2.2E-19 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 LH59_08740 971b657c0ae1bf09cde044e2842449c9 251 SUPERFAMILY SSF53448 1 146 1.45E-29 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases LH59_08740 971b657c0ae1bf09cde044e2842449c9 251 Gene3D G3DSA:3.90.550.10 1 158 2.9E-28 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases LH59_05165 c27215276a2a4b7cf46c18bb96c3d7c9 287 Pfam PF01614 Bacterial transcriptional regulator 143 262 2.0E-32 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal LH59_05165 c27215276a2a4b7cf46c18bb96c3d7c9 287 SMART SM00346 25 114 4.3E-23 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_05165 c27215276a2a4b7cf46c18bb96c3d7c9 287 Gene3D G3DSA:3.30.450.40 96 274 3.5E-55 T 14-10-2018 IPR029016 GAF-like domain superfamily LH59_05165 c27215276a2a4b7cf46c18bb96c3d7c9 287 SUPERFAMILY SSF55781 82 267 3.79E-47 T 14-10-2018 LH59_05165 c27215276a2a4b7cf46c18bb96c3d7c9 287 Gene3D G3DSA:1.10.10.10 23 95 2.3E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_05165 c27215276a2a4b7cf46c18bb96c3d7c9 287 SUPERFAMILY SSF46785 25 96 4.49E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_05165 c27215276a2a4b7cf46c18bb96c3d7c9 287 Pfam PF09339 IclR helix-turn-helix domain 28 77 3.1E-16 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_08530 65c95accd9baab3b549cf80bea594f6f 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 218 4.7E-20 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_08530 65c95accd9baab3b549cf80bea594f6f 223 Gene3D G3DSA:3.40.50.2300 1 122 2.6E-39 T 14-10-2018 LH59_08530 65c95accd9baab3b549cf80bea594f6f 223 Pfam PF00072 Response regulator receiver domain 3 112 4.2E-29 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_08530 65c95accd9baab3b549cf80bea594f6f 223 Gene3D G3DSA:1.10.10.10 123 223 2.2E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_08530 65c95accd9baab3b549cf80bea594f6f 223 SUPERFAMILY SSF52172 1 170 8.4E-40 T 14-10-2018 IPR011006 CheY-like superfamily LH59_08530 65c95accd9baab3b549cf80bea594f6f 223 SMART SM00862 145 218 9.4E-21 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_08530 65c95accd9baab3b549cf80bea594f6f 223 SMART SM00448 1 112 2.0E-41 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_10500 a89f02764495aef22ee5618d2e09ebbf 53 Pfam PF04995 Heme exporter protein D (CcmD) 11 47 5.6E-9 T 14-10-2018 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 LH59_10500 a89f02764495aef22ee5618d2e09ebbf 53 TIGRFAM TIGR03141 cytochro_ccmD: heme exporter protein CcmD 9 47 4.5E-9 T 14-10-2018 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 LH59_22375 e5a23fa9513286f7c18d4b94e3db3c5f 238 Gene3D G3DSA:3.40.50.300 5 236 4.9E-49 T 14-10-2018 LH59_22375 e5a23fa9513286f7c18d4b94e3db3c5f 238 TIGRFAM TIGR02324 CP_lyasePhnL: phosphonate C-P lyase system protein PhnL 7 228 9.6E-98 T 14-10-2018 IPR012701 Phosphonate C-P lyase system, PhnL KEGG: 00440+2.7.8.37|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 LH59_22375 e5a23fa9513286f7c18d4b94e3db3c5f 238 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_22375 e5a23fa9513286f7c18d4b94e3db3c5f 238 Pfam PF00005 ABC transporter 30 184 7.6E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_22375 e5a23fa9513286f7c18d4b94e3db3c5f 238 SUPERFAMILY SSF52540 6 230 1.1E-46 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_22375 e5a23fa9513286f7c18d4b94e3db3c5f 238 SMART SM00382 39 231 5.0E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_03470 116169ca630352c917713f22e3b747a6 285 SUPERFAMILY SSF46785 5 112 4.45E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_03470 116169ca630352c917713f22e3b747a6 285 SUPERFAMILY SSF53850 90 281 5.61E-21 T 14-10-2018 LH59_03470 116169ca630352c917713f22e3b747a6 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.5E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_03470 116169ca630352c917713f22e3b747a6 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.5E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_03470 116169ca630352c917713f22e3b747a6 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.5E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_03470 116169ca630352c917713f22e3b747a6 285 Gene3D G3DSA:3.40.190.10 162 255 5.4E-43 T 14-10-2018 LH59_03470 116169ca630352c917713f22e3b747a6 285 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 3.6E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_03470 116169ca630352c917713f22e3b747a6 285 Gene3D G3DSA:3.40.190.10 97 261 5.4E-43 T 14-10-2018 LH59_03470 116169ca630352c917713f22e3b747a6 285 Gene3D G3DSA:1.10.10.10 6 96 4.9E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_03470 116169ca630352c917713f22e3b747a6 285 Pfam PF03466 LysR substrate binding domain 89 277 3.5E-20 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_02395 34539eca1de4d69fe9582d62b5433aaa 289 Gene3D G3DSA:3.40.50.620 6 144 5.9E-27 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LH59_02395 34539eca1de4d69fe9582d62b5433aaa 289 SUPERFAMILY SSF52402 146 284 1.67E-24 T 14-10-2018 LH59_02395 34539eca1de4d69fe9582d62b5433aaa 289 SUPERFAMILY SSF52402 7 144 3.6E-27 T 14-10-2018 LH59_02395 34539eca1de4d69fe9582d62b5433aaa 289 Gene3D G3DSA:3.40.50.620 145 286 1.8E-25 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LH59_02395 34539eca1de4d69fe9582d62b5433aaa 289 Pfam PF00582 Universal stress protein family 8 141 3.2E-24 T 14-10-2018 IPR006016 UspA LH59_02395 34539eca1de4d69fe9582d62b5433aaa 289 Pfam PF00582 Universal stress protein family 148 284 3.9E-21 T 14-10-2018 IPR006016 UspA LH59_02395 34539eca1de4d69fe9582d62b5433aaa 289 PRINTS PR01438 Universal stress protein signature 244 256 4.3E-13 T 14-10-2018 IPR006015 Universal stress protein A LH59_02395 34539eca1de4d69fe9582d62b5433aaa 289 PRINTS PR01438 Universal stress protein signature 262 284 4.3E-13 T 14-10-2018 IPR006015 Universal stress protein A LH59_02395 34539eca1de4d69fe9582d62b5433aaa 289 PRINTS PR01438 Universal stress protein signature 148 166 4.3E-13 T 14-10-2018 IPR006015 Universal stress protein A LH59_14595 489d68c23192ecc42b6a3b7c7a8cede4 308 Gene3D G3DSA:3.40.190.290 92 298 7.8E-33 T 14-10-2018 LH59_14595 489d68c23192ecc42b6a3b7c7a8cede4 308 Pfam PF03466 LysR substrate binding domain 92 294 5.1E-34 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_14595 489d68c23192ecc42b6a3b7c7a8cede4 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 4.9E-19 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_14595 489d68c23192ecc42b6a3b7c7a8cede4 308 SUPERFAMILY SSF53850 92 295 2.79E-33 T 14-10-2018 LH59_14595 489d68c23192ecc42b6a3b7c7a8cede4 308 Gene3D G3DSA:1.10.10.10 4 88 1.1E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_14595 489d68c23192ecc42b6a3b7c7a8cede4 308 SUPERFAMILY SSF46785 6 111 8.16E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_24350 4af009c578b4bd9f6037df8696760e54 328 Pfam PF02653 Branched-chain amino acid transport system / permease component 35 296 1.5E-34 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_17700 7f42e1237f655f38cf851e0ea85df6d7 953 SUPERFAMILY SSF47323 673 943 6.73E-70 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 LH59_17700 7f42e1237f655f38cf851e0ea85df6d7 953 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 57 68 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 LH59_17700 7f42e1237f655f38cf851e0ea85df6d7 953 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 408 423 9.3E-32 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 LH59_17700 7f42e1237f655f38cf851e0ea85df6d7 953 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 539 552 9.3E-32 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 LH59_17700 7f42e1237f655f38cf851e0ea85df6d7 953 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 50 61 9.3E-32 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 LH59_17700 7f42e1237f655f38cf851e0ea85df6d7 953 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 233 256 9.3E-32 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 LH59_17700 7f42e1237f655f38cf851e0ea85df6d7 953 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 582 591 9.3E-32 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 LH59_17700 7f42e1237f655f38cf851e0ea85df6d7 953 SUPERFAMILY SSF52374 1 670 3.05E-132 T 14-10-2018 LH59_17700 7f42e1237f655f38cf851e0ea85df6d7 953 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 14 869 1.2E-260 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 LH59_17700 7f42e1237f655f38cf851e0ea85df6d7 953 Gene3D G3DSA:3.40.50.620 24 650 1.9E-215 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LH59_17700 7f42e1237f655f38cf851e0ea85df6d7 953 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 27 661 3.8E-188 T 14-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 LH59_17700 7f42e1237f655f38cf851e0ea85df6d7 953 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 1 944 20.623 T 14-10-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 LH59_17700 7f42e1237f655f38cf851e0ea85df6d7 953 Pfam PF08264 Anticodon-binding domain of tRNA 706 867 5.3E-25 T 14-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 LH59_17700 7f42e1237f655f38cf851e0ea85df6d7 953 Gene3D G3DSA:1.10.730.20 661 944 4.6E-87 T 14-10-2018 LH59_17700 7f42e1237f655f38cf851e0ea85df6d7 953 SUPERFAMILY SSF50677 200 410 9.94E-50 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 LH59_17700 7f42e1237f655f38cf851e0ea85df6d7 953 Pfam PF06827 Zinc finger found in FPG and IleRS 914 941 5.4E-6 T 14-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 LH59_17700 7f42e1237f655f38cf851e0ea85df6d7 953 Gene3D G3DSA:3.90.740.10 191 415 1.9E-215 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 LH59_00660 08b14d54a1c3f9581a156e85d714c855 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 288 1.9E-19 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_00660 08b14d54a1c3f9581a156e85d714c855 291 Gene3D G3DSA:1.10.3720.10 48 289 7.8E-69 T 14-10-2018 IPR035906 MetI-like superfamily LH59_00660 08b14d54a1c3f9581a156e85d714c855 291 SUPERFAMILY SSF161098 52 277 8.24E-60 T 14-10-2018 IPR035906 MetI-like superfamily LH59_28055 7a9276577aeb92dcbac5cbb73f39a0e9 336 SUPERFAMILY SSF53850 24 331 8.7E-63 T 14-10-2018 LH59_28055 7a9276577aeb92dcbac5cbb73f39a0e9 336 Pfam PF13343 Bacterial extracellular solute-binding protein 74 298 1.3E-29 T 14-10-2018 LH59_28055 7a9276577aeb92dcbac5cbb73f39a0e9 336 PIRSF PIRSF002825 12 335 4.9E-73 T 14-10-2018 IPR026045 Ferric binding protein LH59_28055 7a9276577aeb92dcbac5cbb73f39a0e9 336 Gene3D G3DSA:3.40.190.10 29 304 4.3E-80 T 14-10-2018 LH59_28055 7a9276577aeb92dcbac5cbb73f39a0e9 336 Gene3D G3DSA:3.40.190.10 128 316 4.3E-80 T 14-10-2018 LH59_26920 be2d2bd36899cafecdf8949fda9d027f 488 SUPERFAMILY SSF52540 296 486 5.33E-23 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_26920 be2d2bd36899cafecdf8949fda9d027f 488 Gene3D G3DSA:3.40.50.300 1 236 2.0E-62 T 14-10-2018 LH59_26920 be2d2bd36899cafecdf8949fda9d027f 488 Gene3D G3DSA:3.40.50.300 243 488 8.1E-97 T 14-10-2018 LH59_26920 be2d2bd36899cafecdf8949fda9d027f 488 SUPERFAMILY SSF52540 43 231 5.51E-10 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_26920 be2d2bd36899cafecdf8949fda9d027f 488 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 13 235 3.2E-38 T 14-10-2018 IPR022488 Polyphosphate kinase-2-related LH59_26920 be2d2bd36899cafecdf8949fda9d027f 488 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 264 486 2.1E-83 T 14-10-2018 IPR022488 Polyphosphate kinase-2-related LH59_26920 be2d2bd36899cafecdf8949fda9d027f 488 TIGRFAM TIGR03708 poly_P_AMP_trns: polyphosphate:AMP phosphotransferase 2 488 1.0E-198 T 14-10-2018 IPR022489 Polyphosphate:AMP phosphotransferase GO:0006797|GO:0043751 LH59_09085 6dc81a4379d6861d4f9756c1d9edaacf 150 Pfam PF03524 Conjugal transfer protein 40 110 4.5E-14 T 14-10-2018 IPR010258 Conjugal transfer, TrbG/VirB9/CagX LH59_09085 6dc81a4379d6861d4f9756c1d9edaacf 150 Gene3D G3DSA:2.60.40.2500 35 131 1.3E-12 T 14-10-2018 IPR038161 VirB9/CagX/TrbG, C-terminal domain superfamily LH59_25820 966513e14bb215fe2161614876b69b7d 411 Pfam PF13458 Periplasmic binding protein 23 372 1.1E-69 T 14-10-2018 IPR028081 Leucine-binding protein domain LH59_25820 966513e14bb215fe2161614876b69b7d 411 Gene3D G3DSA:3.40.50.2300 150 405 3.5E-141 T 14-10-2018 LH59_25820 966513e14bb215fe2161614876b69b7d 411 Gene3D G3DSA:3.40.50.2300 23 364 3.5E-141 T 14-10-2018 LH59_25820 966513e14bb215fe2161614876b69b7d 411 SUPERFAMILY SSF53822 23 378 6.28E-67 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_22925 6bc46e2a054c4021f06930795dc03196 958 SUPERFAMILY SSF53706 241 771 2.62E-192 T 14-10-2018 LH59_22925 6bc46e2a054c4021f06930795dc03196 958 SUPERFAMILY SSF54862 96 233 5.44E-38 T 14-10-2018 LH59_22925 6bc46e2a054c4021f06930795dc03196 958 Pfam PF00384 Molybdopterin oxidoreductase 297 728 1.0E-74 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_22925 6bc46e2a054c4021f06930795dc03196 958 Pfam PF00037 4Fe-4S binding domain 211 226 2.9E-5 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain LH59_22925 6bc46e2a054c4021f06930795dc03196 958 PIRSF PIRSF036643 18 954 0.0 T 14-10-2018 LH59_22925 6bc46e2a054c4021f06930795dc03196 958 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 213 224 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site LH59_22925 6bc46e2a054c4021f06930795dc03196 958 Gene3D G3DSA:2.40.40.20 809 923 1.2E-35 T 14-10-2018 LH59_22925 6bc46e2a054c4021f06930795dc03196 958 SMART SM00929 104 144 9.9E-19 T 14-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_22925 6bc46e2a054c4021f06930795dc03196 958 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 241 292 2.7E-16 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_22925 6bc46e2a054c4021f06930795dc03196 958 Gene3D G3DSA:3.30.70.20 149 231 6.4E-24 T 14-10-2018 LH59_22925 6bc46e2a054c4021f06930795dc03196 958 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 21 97 6.5E-23 T 14-10-2018 LH59_22925 6bc46e2a054c4021f06930795dc03196 958 SUPERFAMILY SSF54292 22 95 2.42E-20 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 LH59_22925 6bc46e2a054c4021f06930795dc03196 958 SUPERFAMILY SSF50692 768 923 1.99E-41 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily LH59_22925 6bc46e2a054c4021f06930795dc03196 958 SMART SM00926 240 294 3.1E-16 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_22925 6bc46e2a054c4021f06930795dc03196 958 Gene3D G3DSA:3.40.50.740 302 771 9.7E-173 T 14-10-2018 LH59_22925 6bc46e2a054c4021f06930795dc03196 958 Gene3D G3DSA:3.40.228.10 377 584 9.7E-173 T 14-10-2018 LH59_22925 6bc46e2a054c4021f06930795dc03196 958 Gene3D G3DSA:3.10.20.740 22 143 6.1E-40 T 14-10-2018 LH59_22925 6bc46e2a054c4021f06930795dc03196 958 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 245 920 3.5E-284 T 14-10-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.17.1.9|KEGG: 00680+1.17.1.9|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696|MetaCyc: PWY-7985 LH59_22925 6bc46e2a054c4021f06930795dc03196 958 Pfam PF01568 Molydopterin dinucleotide binding domain 812 916 7.8E-28 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 LH59_22925 6bc46e2a054c4021f06930795dc03196 958 Gene3D G3DSA:2.20.25.90 241 293 7.6E-17 T 14-10-2018 LH59_22925 6bc46e2a054c4021f06930795dc03196 958 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 104 143 8.5E-17 T 14-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_24120 90caf943c93eb5f3460f9a87afa11d23 401 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 344 363 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 LH59_24120 90caf943c93eb5f3460f9a87afa11d23 401 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 111 1.4E-27 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 LH59_24120 90caf943c93eb5f3460f9a87afa11d23 401 Gene3D G3DSA:1.20.140.10 241 393 4.3E-44 T 14-10-2018 LH59_24120 90caf943c93eb5f3460f9a87afa11d23 401 Gene3D G3DSA:1.10.540.10 2 118 5.6E-32 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 LH59_24120 90caf943c93eb5f3460f9a87afa11d23 401 SUPERFAMILY SSF56645 3 227 1.44E-54 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 LH59_24120 90caf943c93eb5f3460f9a87afa11d23 401 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 120 218 9.1E-19 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 LH59_24120 90caf943c93eb5f3460f9a87afa11d23 401 PIRSF PIRSF016578 1 208 1.7E-10 T 14-10-2018 LH59_24120 90caf943c93eb5f3460f9a87afa11d23 401 PIRSF PIRSF016578 220 393 1.0E-11 T 14-10-2018 LH59_24120 90caf943c93eb5f3460f9a87afa11d23 401 Gene3D G3DSA:2.40.110.10 120 240 2.6E-26 T 14-10-2018 LH59_24120 90caf943c93eb5f3460f9a87afa11d23 401 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 235 385 1.8E-37 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LH59_24120 90caf943c93eb5f3460f9a87afa11d23 401 SUPERFAMILY SSF47203 234 391 3.22E-45 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 LH59_27705 82d08db48c6c357ef97d4684ac7a7718 613 Hamap MF_00399 Thiol:disulfide interchange protein DsbD [dsbD]. 1 611 34.187 T 14-10-2018 IPR022910 Thiol:disulphide interchange protein DsbD GO:0047134|GO:0055114 LH59_27705 82d08db48c6c357ef97d4684ac7a7718 613 SUPERFAMILY SSF74863 27 146 7.06E-33 T 14-10-2018 IPR036929 Thiol:disulfide interchange protein DsbD, N-terminal domain superfamily LH59_27705 82d08db48c6c357ef97d4684ac7a7718 613 SUPERFAMILY SSF52833 503 608 1.42E-19 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_27705 82d08db48c6c357ef97d4684ac7a7718 613 ProSitePatterns PS00194 Thioredoxin family active site. 519 537 - T 14-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 LH59_27705 82d08db48c6c357ef97d4684ac7a7718 613 Gene3D G3DSA:3.40.30.10 488 610 8.4E-28 T 14-10-2018 LH59_27705 82d08db48c6c357ef97d4684ac7a7718 613 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 200 400 1.8E-17 T 14-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 LH59_27705 82d08db48c6c357ef97d4684ac7a7718 613 Gene3D G3DSA:2.60.40.1250 22 154 1.1E-37 T 14-10-2018 IPR036929 Thiol:disulfide interchange protein DsbD, N-terminal domain superfamily LH59_27705 82d08db48c6c357ef97d4684ac7a7718 613 Pfam PF13899 Thioredoxin-like 511 584 2.6E-9 T 14-10-2018 LH59_27705 82d08db48c6c357ef97d4684ac7a7718 613 Pfam PF11412 Disulphide bond corrector protein DsbC 29 145 1.2E-32 T 14-10-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain LH59_10805 275eab0a63182b13cc475cd666518d0a 1204 SUPERFAMILY SSF52540 947 1189 1.26E-86 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_10805 275eab0a63182b13cc475cd666518d0a 1204 ProSitePatterns PS00211 ABC transporters family signature. 474 488 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_10805 275eab0a63182b13cc475cd666518d0a 1204 SUPERFAMILY SSF52540 331 572 1.18E-85 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_10805 275eab0a63182b13cc475cd666518d0a 1204 Pfam PF00005 ABC transporter 355 501 1.5E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_10805 275eab0a63182b13cc475cd666518d0a 1204 Gene3D G3DSA:1.20.1560.10 625 934 8.6E-51 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 LH59_10805 275eab0a63182b13cc475cd666518d0a 1204 Gene3D G3DSA:1.20.1560.10 5 319 6.4E-43 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 LH59_10805 275eab0a63182b13cc475cd666518d0a 1204 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 627 1149 1.7E-99 T 14-10-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0016021|GO:0034775|GO:0042626|GO:0045454 LH59_10805 275eab0a63182b13cc475cd666518d0a 1204 Pfam PF00664 ABC transporter transmembrane region 640 900 2.3E-19 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 LH59_10805 275eab0a63182b13cc475cd666518d0a 1204 Pfam PF00664 ABC transporter transmembrane region 21 280 8.6E-23 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 LH59_10805 275eab0a63182b13cc475cd666518d0a 1204 SUPERFAMILY SSF90123 628 941 1.03E-51 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 LH59_10805 275eab0a63182b13cc475cd666518d0a 1204 ProSitePatterns PS00211 ABC transporters family signature. 1091 1105 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_10805 275eab0a63182b13cc475cd666518d0a 1204 Gene3D G3DSA:3.40.50.300 945 1191 2.3E-84 T 14-10-2018 LH59_10805 275eab0a63182b13cc475cd666518d0a 1204 SUPERFAMILY SSF90123 6 317 1.57E-47 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 LH59_10805 275eab0a63182b13cc475cd666518d0a 1204 Pfam PF00005 ABC transporter 970 1119 3.7E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_10805 275eab0a63182b13cc475cd666518d0a 1204 SMART SM00382 979 1165 2.0E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_10805 275eab0a63182b13cc475cd666518d0a 1204 SMART SM00382 362 548 4.8E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_10805 275eab0a63182b13cc475cd666518d0a 1204 Gene3D G3DSA:3.40.50.300 331 578 2.8E-88 T 14-10-2018 LH59_05985 52549a94895576d661d62626ba076563 378 Gene3D G3DSA:3.60.60.10 13 354 1.9E-85 T 14-10-2018 LH59_05985 52549a94895576d661d62626ba076563 378 Gene3D G3DSA:1.10.10.2120 28 100 1.9E-85 T 14-10-2018 LH59_05985 52549a94895576d661d62626ba076563 378 Pfam PF03417 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 128 351 1.1E-13 T 14-10-2018 IPR005079 Peptidase C45 LH59_05845 b35fbfdafd16f5ce9a3fafa094d7bac7 316 Pfam PF16220 Domain of unknown function (DUF4880) 8 49 2.5E-11 T 14-10-2018 IPR032623 FecR, N-terminal LH59_05845 b35fbfdafd16f5ce9a3fafa094d7bac7 316 PIRSF PIRSF018266 1 315 7.0E-81 T 14-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component LH59_05845 b35fbfdafd16f5ce9a3fafa094d7bac7 316 Gene3D G3DSA:2.60.120.1440 96 232 4.1E-13 T 14-10-2018 LH59_05845 b35fbfdafd16f5ce9a3fafa094d7bac7 316 Pfam PF04773 FecR protein 108 201 3.1E-16 T 14-10-2018 IPR006860 FecR protein LH59_02950 4d5873a8591ca92e5a4c60a6a89c607d 389 Gene3D G3DSA:2.40.110.10 131 242 7.6E-47 T 14-10-2018 LH59_02950 4d5873a8591ca92e5a4c60a6a89c607d 389 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 14 128 4.7E-11 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 LH59_02950 4d5873a8591ca92e5a4c60a6a89c607d 389 Gene3D G3DSA:1.20.140.10 243 389 6.5E-44 T 14-10-2018 LH59_02950 4d5873a8591ca92e5a4c60a6a89c607d 389 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 134 146 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 LH59_02950 4d5873a8591ca92e5a4c60a6a89c607d 389 SUPERFAMILY SSF56645 11 248 1.23E-62 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 LH59_02950 4d5873a8591ca92e5a4c60a6a89c607d 389 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 132 225 6.5E-23 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 LH59_02950 4d5873a8591ca92e5a4c60a6a89c607d 389 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 237 386 1.1E-43 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LH59_02950 4d5873a8591ca92e5a4c60a6a89c607d 389 SUPERFAMILY SSF47203 235 388 1.11E-47 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 LH59_02950 4d5873a8591ca92e5a4c60a6a89c607d 389 Gene3D G3DSA:1.10.540.10 8 130 1.3E-24 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 LH59_26460 136ead4d8ca5be20ec4c2939324fad0b 105 SUPERFAMILY SSF103481 4 102 8.89E-20 T 14-10-2018 LH59_26460 136ead4d8ca5be20ec4c2939324fad0b 105 Gene3D G3DSA:1.10.3730.20 1 105 1.1E-30 T 14-10-2018 LH59_26460 136ead4d8ca5be20ec4c2939324fad0b 105 Pfam PF00893 Small Multidrug Resistance protein 1 93 3.2E-24 T 14-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 LH59_15830 6ab28bf3a3d2b8990a73cd668802661c 134 SUPERFAMILY SSF46458 5 116 2.4E-25 T 14-10-2018 IPR009050 Globin-like superfamily LH59_15830 6ab28bf3a3d2b8990a73cd668802661c 134 Gene3D G3DSA:1.10.490.10 3 120 1.9E-37 T 14-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 LH59_15675 71c32d7b80e5a3b39422bfd06e188f89 148 Pfam PF00582 Universal stress protein family 1 145 4.0E-31 T 14-10-2018 IPR006016 UspA LH59_15675 71c32d7b80e5a3b39422bfd06e188f89 148 PRINTS PR01438 Universal stress protein signature 105 117 4.8E-16 T 14-10-2018 IPR006015 Universal stress protein A LH59_15675 71c32d7b80e5a3b39422bfd06e188f89 148 PRINTS PR01438 Universal stress protein signature 123 145 4.8E-16 T 14-10-2018 IPR006015 Universal stress protein A LH59_15675 71c32d7b80e5a3b39422bfd06e188f89 148 PRINTS PR01438 Universal stress protein signature 2 20 4.8E-16 T 14-10-2018 IPR006015 Universal stress protein A LH59_15675 71c32d7b80e5a3b39422bfd06e188f89 148 Gene3D G3DSA:3.40.50.620 1 147 6.3E-38 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LH59_15675 71c32d7b80e5a3b39422bfd06e188f89 148 SUPERFAMILY SSF52402 1 145 1.26E-37 T 14-10-2018 LH59_19235 dea53686a86be52c5ffc1000225fe8a1 337 Pfam PF02625 XdhC and CoxI family 15 87 1.3E-21 T 14-10-2018 IPR003777 XdhC- CoxI LH59_19235 dea53686a86be52c5ffc1000225fe8a1 337 Pfam PF13478 XdhC Rossmann domain 169 311 4.4E-33 T 14-10-2018 IPR027051 XdhC Rossmann domain LH59_19235 dea53686a86be52c5ffc1000225fe8a1 337 Gene3D G3DSA:3.40.50.720 168 317 4.5E-39 T 14-10-2018 LH59_08160 c1990876945a05bf8d40a32a9685b6b1 357 SUPERFAMILY SSF51569 7 348 4.5E-137 T 14-10-2018 LH59_08160 c1990876945a05bf8d40a32a9685b6b1 357 PIRSF PIRSF001361 1 352 8.8E-161 T 14-10-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 LH59_08160 c1990876945a05bf8d40a32a9685b6b1 357 Pfam PF00793 DAHP synthetase I family 40 338 9.8E-103 T 14-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 LH59_08160 c1990876945a05bf8d40a32a9685b6b1 357 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 6 349 4.3E-164 T 14-10-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 LH59_08160 c1990876945a05bf8d40a32a9685b6b1 357 Gene3D G3DSA:3.20.20.70 1 350 1.5E-163 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_23545 28132d7cc524cc0d86a16b814d5a4215 817 Gene3D G3DSA:3.55.50.30 54 125 7.5E-24 T 14-10-2018 LH59_23545 28132d7cc524cc0d86a16b814d5a4215 817 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 800 817 - T 14-10-2018 IPR010917 TonB-dependent receptor, conserved site LH59_23545 28132d7cc524cc0d86a16b814d5a4215 817 Gene3D G3DSA:2.40.170.20 290 817 1.9E-87 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_23545 28132d7cc524cc0d86a16b814d5a4215 817 Pfam PF07715 TonB-dependent Receptor Plug Domain 174 276 1.6E-14 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_23545 28132d7cc524cc0d86a16b814d5a4215 817 SMART SM00965 76 127 1.8E-11 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 LH59_23545 28132d7cc524cc0d86a16b814d5a4215 817 SUPERFAMILY SSF56935 132 817 1.04E-110 T 14-10-2018 LH59_23545 28132d7cc524cc0d86a16b814d5a4215 817 Gene3D G3DSA:2.170.130.10 169 289 1.7E-22 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily LH59_23545 28132d7cc524cc0d86a16b814d5a4215 817 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 176 817 2.8E-113 T 14-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 LH59_23545 28132d7cc524cc0d86a16b814d5a4215 817 Pfam PF00593 TonB dependent receptor 390 815 1.3E-41 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_11145 b1915694293fbf3048bdc10126a96d4e 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 312 7.0E-40 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_11145 b1915694293fbf3048bdc10126a96d4e 314 SUPERFAMILY SSF161098 92 297 7.19E-20 T 14-10-2018 IPR035906 MetI-like superfamily LH59_11145 b1915694293fbf3048bdc10126a96d4e 314 Gene3D G3DSA:1.10.3720.10 85 305 3.3E-27 T 14-10-2018 IPR035906 MetI-like superfamily LH59_24520 ee502ca4b1de40ccb47e3f1eb20ee4d9 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 1.8E-34 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 LH59_24520 ee502ca4b1de40ccb47e3f1eb20ee4d9 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 1.8E-34 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 LH59_24520 ee502ca4b1de40ccb47e3f1eb20ee4d9 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 1.8E-34 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 LH59_24520 ee502ca4b1de40ccb47e3f1eb20ee4d9 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 1.8E-34 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 LH59_24520 ee502ca4b1de40ccb47e3f1eb20ee4d9 363 Pfam PF06071 Protein of unknown function (DUF933) 279 362 2.0E-39 T 14-10-2018 IPR013029 YchF, C-terminal domain Reactome: R-HSA-114608 LH59_24520 ee502ca4b1de40ccb47e3f1eb20ee4d9 363 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 363 43.75 T 14-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 LH59_24520 ee502ca4b1de40ccb47e3f1eb20ee4d9 363 Gene3D G3DSA:3.40.50.300 3 278 7.8E-150 T 14-10-2018 LH59_24520 ee502ca4b1de40ccb47e3f1eb20ee4d9 363 PIRSF PIRSF006641 1 363 5.5E-151 T 14-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 LH59_24520 ee502ca4b1de40ccb47e3f1eb20ee4d9 363 Gene3D G3DSA:3.10.20.30 48 361 7.8E-150 T 14-10-2018 IPR012675 Beta-grasp domain superfamily LH59_24520 ee502ca4b1de40ccb47e3f1eb20ee4d9 363 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 363 7.0E-156 T 14-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 LH59_24520 ee502ca4b1de40ccb47e3f1eb20ee4d9 363 SUPERFAMILY SSF81271 279 359 4.36E-36 T 14-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 LH59_24520 ee502ca4b1de40ccb47e3f1eb20ee4d9 363 SUPERFAMILY SSF52540 3 301 2.59E-86 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_24520 ee502ca4b1de40ccb47e3f1eb20ee4d9 363 Gene3D G3DSA:1.10.150.300 113 200 7.8E-150 T 14-10-2018 IPR023192 TGS-like domain superfamily Reactome: R-HSA-114608 LH59_24520 ee502ca4b1de40ccb47e3f1eb20ee4d9 363 Pfam PF01926 50S ribosome-binding GTPase 5 122 1.2E-22 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 LH59_21630 fe3b9c16cb84ff196cd7c1a96364aaba 315 Gene3D G3DSA:1.10.10.10 3 96 1.7E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_21630 fe3b9c16cb84ff196cd7c1a96364aaba 315 Gene3D G3DSA:3.40.190.10 162 258 4.4E-46 T 14-10-2018 LH59_21630 fe3b9c16cb84ff196cd7c1a96364aaba 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 2.7E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_21630 fe3b9c16cb84ff196cd7c1a96364aaba 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 2.7E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_21630 fe3b9c16cb84ff196cd7c1a96364aaba 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 2.7E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_21630 fe3b9c16cb84ff196cd7c1a96364aaba 315 Pfam PF03466 LysR substrate binding domain 90 291 3.6E-35 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_21630 fe3b9c16cb84ff196cd7c1a96364aaba 315 Gene3D G3DSA:3.40.190.10 102 287 4.4E-46 T 14-10-2018 LH59_21630 fe3b9c16cb84ff196cd7c1a96364aaba 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 6.7E-20 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_21630 fe3b9c16cb84ff196cd7c1a96364aaba 315 SUPERFAMILY SSF53850 90 294 4.52E-40 T 14-10-2018 LH59_21630 fe3b9c16cb84ff196cd7c1a96364aaba 315 SUPERFAMILY SSF46785 2 80 5.44E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_11340 42b2f55620178a3147f14ed3389b9112 352 Gene3D G3DSA:3.40.50.180 152 349 8.8E-79 T 14-10-2018 IPR035909 Methylesterase CheB, C-terminal LH59_11340 42b2f55620178a3147f14ed3389b9112 352 Gene3D G3DSA:3.40.50.2300 1 133 2.8E-31 T 14-10-2018 LH59_11340 42b2f55620178a3147f14ed3389b9112 352 PIRSF PIRSF000876 1 349 3.4E-138 T 14-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 LH59_11340 42b2f55620178a3147f14ed3389b9112 352 SMART SM00448 4 123 1.3E-22 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_11340 42b2f55620178a3147f14ed3389b9112 352 Pfam PF00072 Response regulator receiver domain 6 108 7.7E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_11340 42b2f55620178a3147f14ed3389b9112 352 SUPERFAMILY SSF52172 1 108 1.57E-28 T 14-10-2018 IPR011006 CheY-like superfamily LH59_11340 42b2f55620178a3147f14ed3389b9112 352 SUPERFAMILY SSF52738 157 346 1.7E-71 T 14-10-2018 IPR035909 Methylesterase CheB, C-terminal LH59_11340 42b2f55620178a3147f14ed3389b9112 352 Pfam PF01339 CheB methylesterase 162 341 1.9E-61 T 14-10-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 LH59_11340 42b2f55620178a3147f14ed3389b9112 352 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 4 346 41.542 T 14-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 LH59_09780 d6a13c2b4b3a9076c65857c4051ee14d 156 SUPERFAMILY SSF54909 66 155 2.28E-21 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel LH59_09780 d6a13c2b4b3a9076c65857c4051ee14d 156 SUPERFAMILY SSF46785 4 96 2.23E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_09780 d6a13c2b4b3a9076c65857c4051ee14d 156 Pfam PF13412 Winged helix-turn-helix DNA-binding 6 52 1.0E-19 T 14-10-2018 LH59_09780 d6a13c2b4b3a9076c65857c4051ee14d 156 Gene3D G3DSA:3.30.70.920 60 143 2.8E-27 T 14-10-2018 LH59_09780 d6a13c2b4b3a9076c65857c4051ee14d 156 Pfam PF01037 Lrp/AsnC ligand binding domain 72 146 4.0E-25 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LH59_09780 d6a13c2b4b3a9076c65857c4051ee14d 156 Gene3D G3DSA:1.10.10.10 1 59 8.0E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_09780 d6a13c2b4b3a9076c65857c4051ee14d 156 ProSitePatterns PS00519 AsnC-type HTH domain signature. 24 50 - T 14-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site LH59_09780 d6a13c2b4b3a9076c65857c4051ee14d 156 SMART SM00344 6 115 1.5E-42 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 LH59_09780 d6a13c2b4b3a9076c65857c4051ee14d 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 22 2.7E-16 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_09780 d6a13c2b4b3a9076c65857c4051ee14d 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 33 2.7E-16 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_09780 d6a13c2b4b3a9076c65857c4051ee14d 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 52 2.7E-16 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_03770 3d5bc0976b1ddca7ee18a1c7a6b90b4e 269 SUPERFAMILY SSF53474 9 268 1.04E-48 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_03770 3d5bc0976b1ddca7ee18a1c7a6b90b4e 269 Gene3D G3DSA:3.40.50.1820 5 268 6.4E-47 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_03770 3d5bc0976b1ddca7ee18a1c7a6b90b4e 269 Pfam PF12697 Alpha/beta hydrolase family 30 260 3.2E-15 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_00180 0da65e94e2e4b9f5a0e11debf71c5604 343 Gene3D G3DSA:3.40.190.10 127 337 1.8E-80 T 14-10-2018 LH59_00180 0da65e94e2e4b9f5a0e11debf71c5604 343 SUPERFAMILY SSF53850 25 338 1.25E-58 T 14-10-2018 LH59_00180 0da65e94e2e4b9f5a0e11debf71c5604 343 Gene3D G3DSA:3.40.190.10 40 309 1.8E-80 T 14-10-2018 LH59_00180 0da65e94e2e4b9f5a0e11debf71c5604 343 Pfam PF13343 Bacterial extracellular solute-binding protein 77 329 2.7E-32 T 14-10-2018 LH59_12980 58183adf1cd02006e9dd940eb71fe1af 317 Pfam PF03466 LysR substrate binding domain 104 307 4.6E-35 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_12980 58183adf1cd02006e9dd940eb71fe1af 317 Gene3D G3DSA:1.10.10.10 16 98 3.0E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_12980 58183adf1cd02006e9dd940eb71fe1af 317 SUPERFAMILY SSF46785 15 128 9.53E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_12980 58183adf1cd02006e9dd940eb71fe1af 317 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 20 79 1.4E-16 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_12980 58183adf1cd02006e9dd940eb71fe1af 317 Gene3D G3DSA:3.40.190.290 108 311 7.6E-27 T 14-10-2018 LH59_12980 58183adf1cd02006e9dd940eb71fe1af 317 SUPERFAMILY SSF53850 107 310 9.05E-35 T 14-10-2018 LH59_12980 58183adf1cd02006e9dd940eb71fe1af 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 46 6.6E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_12980 58183adf1cd02006e9dd940eb71fe1af 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 56 6.6E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_12980 58183adf1cd02006e9dd940eb71fe1af 317 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 56 67 6.6E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_01125 094d8c00fdb2e604edd5000fa993a635 385 PRINTS PR01166 Cytochrome c oxidase subunit II signature 102 122 4.5E-40 T 14-10-2018 LH59_01125 094d8c00fdb2e604edd5000fa993a635 385 PRINTS PR01166 Cytochrome c oxidase subunit II signature 174 195 4.5E-40 T 14-10-2018 LH59_01125 094d8c00fdb2e604edd5000fa993a635 385 PRINTS PR01166 Cytochrome c oxidase subunit II signature 90 102 4.5E-40 T 14-10-2018 LH59_01125 094d8c00fdb2e604edd5000fa993a635 385 PRINTS PR01166 Cytochrome c oxidase subunit II signature 198 218 4.5E-40 T 14-10-2018 LH59_01125 094d8c00fdb2e604edd5000fa993a635 385 PRINTS PR01166 Cytochrome c oxidase subunit II signature 218 235 4.5E-40 T 14-10-2018 LH59_01125 094d8c00fdb2e604edd5000fa993a635 385 PRINTS PR01166 Cytochrome c oxidase subunit II signature 124 143 4.5E-40 T 14-10-2018 LH59_01125 094d8c00fdb2e604edd5000fa993a635 385 PRINTS PR01166 Cytochrome c oxidase subunit II signature 236 253 4.5E-40 T 14-10-2018 LH59_01125 094d8c00fdb2e604edd5000fa993a635 385 SUPERFAMILY SSF81464 28 122 2.13E-25 T 14-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_01125 094d8c00fdb2e604edd5000fa993a635 385 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 31 113 7.7E-13 T 14-10-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_01125 094d8c00fdb2e604edd5000fa993a635 385 Gene3D G3DSA:1.10.760.10 268 385 1.3E-26 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_01125 094d8c00fdb2e604edd5000fa993a635 385 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 199 247 - T 14-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_01125 094d8c00fdb2e604edd5000fa993a635 385 SUPERFAMILY SSF46626 275 370 9.18E-23 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_01125 094d8c00fdb2e604edd5000fa993a635 385 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 42 264 3.4E-58 T 14-10-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_01125 094d8c00fdb2e604edd5000fa993a635 385 Gene3D G3DSA:2.60.40.420 125 267 5.2E-53 T 14-10-2018 IPR008972 Cupredoxin LH59_01125 094d8c00fdb2e604edd5000fa993a635 385 SUPERFAMILY SSF49503 120 318 2.13E-54 T 14-10-2018 IPR008972 Cupredoxin LH59_01125 094d8c00fdb2e604edd5000fa993a635 385 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 286 360 3.0E-12 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_01125 094d8c00fdb2e604edd5000fa993a635 385 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 128 253 7.7E-39 T 14-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_01125 094d8c00fdb2e604edd5000fa993a635 385 Gene3D G3DSA:1.10.287.90 29 124 2.9E-23 T 14-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_16875 84af85c1f67ce5b36601308b8620ec79 314 Pfam PF01882 Protein of unknown function DUF58 49 133 1.2E-18 T 14-10-2018 IPR002881 Domain of unknown function DUF58 LH59_16875 84af85c1f67ce5b36601308b8620ec79 314 SUPERFAMILY SSF53300 85 218 2.78E-8 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily LH59_13345 83434a19d0d6902ffb819a968db774ff 331 PIRSF PIRSF002786 8 331 1.4E-55 T 14-10-2018 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 LH59_13345 83434a19d0d6902ffb819a968db774ff 331 Gene3D G3DSA:1.10.40.60 202 291 4.5E-9 T 14-10-2018 IPR038072 GspK, central domain superfamily LH59_13345 83434a19d0d6902ffb819a968db774ff 331 Gene3D G3DSA:3.30.1300.30 292 316 4.5E-9 T 14-10-2018 LH59_13345 83434a19d0d6902ffb819a968db774ff 331 Gene3D G3DSA:3.30.1300.30 49 109 9.1E-6 T 14-10-2018 LH59_13345 83434a19d0d6902ffb819a968db774ff 331 SUPERFAMILY SSF47781 197 247 1.78E-5 T 14-10-2018 IPR010994 RuvA domain 2-like LH59_13345 83434a19d0d6902ffb819a968db774ff 331 Pfam PF03934 Type II secretion system (T2SS), protein K 37 322 2.7E-49 T 14-10-2018 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 LH59_13345 83434a19d0d6902ffb819a968db774ff 331 Gene3D G3DSA:1.10.40.60 174 201 4.5E-9 T 14-10-2018 IPR038072 GspK, central domain superfamily LH59_13345 83434a19d0d6902ffb819a968db774ff 331 Gene3D G3DSA:1.10.40.60 110 156 9.1E-6 T 14-10-2018 IPR038072 GspK, central domain superfamily LH59_13345 83434a19d0d6902ffb819a968db774ff 331 SUPERFAMILY SSF158544 112 199 2.88E-7 T 14-10-2018 IPR038072 GspK, central domain superfamily LH59_14250 208dfc81327d85cfaca6788d87de79f5 309 Gene3D G3DSA:1.10.10.10 1 85 2.5E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_14250 208dfc81327d85cfaca6788d87de79f5 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 64 6.4E-14 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_14250 208dfc81327d85cfaca6788d87de79f5 309 SUPERFAMILY SSF53850 92 302 2.72E-41 T 14-10-2018 LH59_14250 208dfc81327d85cfaca6788d87de79f5 309 Gene3D G3DSA:3.40.190.10 167 268 5.6E-93 T 14-10-2018 LH59_14250 208dfc81327d85cfaca6788d87de79f5 309 SUPERFAMILY SSF46785 12 113 3.46E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_14250 208dfc81327d85cfaca6788d87de79f5 309 Gene3D G3DSA:3.40.190.10 92 304 5.6E-93 T 14-10-2018 LH59_14250 208dfc81327d85cfaca6788d87de79f5 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 5.5E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_14250 208dfc81327d85cfaca6788d87de79f5 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 5.5E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_14250 208dfc81327d85cfaca6788d87de79f5 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 5.5E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_14250 208dfc81327d85cfaca6788d87de79f5 309 Pfam PF03466 LysR substrate binding domain 90 292 1.1E-40 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_03375 c3f7c2fde731c83fc3ed597dd3e4dbff 354 SUPERFAMILY SSF55347 156 322 4.91E-48 T 14-10-2018 LH59_03375 c3f7c2fde731c83fc3ed597dd3e4dbff 354 SUPERFAMILY SSF51735 7 173 2.06E-54 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_03375 c3f7c2fde731c83fc3ed597dd3e4dbff 354 SMART SM00859 10 148 3.3E-57 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 LH59_03375 c3f7c2fde731c83fc3ed597dd3e4dbff 354 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 10 148 6.3E-37 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 LH59_03375 c3f7c2fde731c83fc3ed597dd3e4dbff 354 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 9 354 1.0E-126 T 14-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 LH59_03375 c3f7c2fde731c83fc3ed597dd3e4dbff 354 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 151 167 - T 14-10-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 LH59_03375 c3f7c2fde731c83fc3ed597dd3e4dbff 354 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 174 325 8.8E-18 T 14-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 LH59_03375 c3f7c2fde731c83fc3ed597dd3e4dbff 354 Gene3D G3DSA:3.30.360.10 154 322 3.0E-126 T 14-10-2018 LH59_03375 c3f7c2fde731c83fc3ed597dd3e4dbff 354 Gene3D G3DSA:3.40.50.720 10 340 3.0E-126 T 14-10-2018 LH59_03375 c3f7c2fde731c83fc3ed597dd3e4dbff 354 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 9 348 41.808 T 14-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 LH59_03755 71f21e902dfceb1ee4a8f83b442f3f3f 703 Pfam PF03764 Elongation factor G, domain IV 484 603 1.6E-48 T 14-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 LH59_03755 71f21e902dfceb1ee4a8f83b442f3f3f 703 SMART SM00838 606 695 6.0E-54 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like LH59_03755 71f21e902dfceb1ee4a8f83b442f3f3f 703 Gene3D G3DSA:3.30.70.870 410 488 1.6E-33 T 14-10-2018 LH59_03755 71f21e902dfceb1ee4a8f83b442f3f3f 703 SUPERFAMILY SSF54980 409 486 1.8E-25 T 14-10-2018 IPR035647 EF-G domain III/V-like LH59_03755 71f21e902dfceb1ee4a8f83b442f3f3f 703 SUPERFAMILY SSF54980 609 697 5.76E-31 T 14-10-2018 IPR035647 EF-G domain III/V-like LH59_03755 71f21e902dfceb1ee4a8f83b442f3f3f 703 Gene3D G3DSA:3.30.70.240 610 682 9.2E-92 T 14-10-2018 LH59_03755 71f21e902dfceb1ee4a8f83b442f3f3f 703 Hamap MF_00054_B Elongation factor G [fusA]. 6 699 111.969 T 14-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 LH59_03755 71f21e902dfceb1ee4a8f83b442f3f3f 703 SUPERFAMILY SSF54211 484 605 1.26E-44 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold LH59_03755 71f21e902dfceb1ee4a8f83b442f3f3f 703 Gene3D G3DSA:3.40.50.300 1 298 3.2E-115 T 14-10-2018 LH59_03755 71f21e902dfceb1ee4a8f83b442f3f3f 703 Gene3D G3DSA:3.30.230.10 489 695 9.2E-92 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup LH59_03755 71f21e902dfceb1ee4a8f83b442f3f3f 703 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 11 187 2.2E-33 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 LH59_03755 71f21e902dfceb1ee4a8f83b442f3f3f 703 Pfam PF14492 Elongation Factor G, domain II 409 483 8.6E-35 T 14-10-2018 LH59_03755 71f21e902dfceb1ee4a8f83b442f3f3f 703 SMART SM00889 485 604 1.4E-76 T 14-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 LH59_03755 71f21e902dfceb1ee4a8f83b442f3f3f 703 Pfam PF00679 Elongation factor G C-terminus 606 694 5.8E-32 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like LH59_03755 71f21e902dfceb1ee4a8f83b442f3f3f 703 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site LH59_03755 71f21e902dfceb1ee4a8f83b442f3f3f 703 Pfam PF00009 Elongation factor Tu GTP binding domain 10 288 1.4E-67 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_03755 71f21e902dfceb1ee4a8f83b442f3f3f 703 PRINTS PR00315 GTP-binding elongation factor signature 85 95 4.2E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_03755 71f21e902dfceb1ee4a8f83b442f3f3f 703 PRINTS PR00315 GTP-binding elongation factor signature 137 146 4.2E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_03755 71f21e902dfceb1ee4a8f83b442f3f3f 703 PRINTS PR00315 GTP-binding elongation factor signature 12 25 4.2E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_03755 71f21e902dfceb1ee4a8f83b442f3f3f 703 PRINTS PR00315 GTP-binding elongation factor signature 58 66 4.2E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_03755 71f21e902dfceb1ee4a8f83b442f3f3f 703 PRINTS PR00315 GTP-binding elongation factor signature 101 112 4.2E-16 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_03755 71f21e902dfceb1ee4a8f83b442f3f3f 703 SUPERFAMILY SSF52540 6 288 4.5E-106 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_03755 71f21e902dfceb1ee4a8f83b442f3f3f 703 Gene3D G3DSA:2.40.30.10 299 405 4.1E-45 T 14-10-2018 LH59_03755 71f21e902dfceb1ee4a8f83b442f3f3f 703 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 699 0.0 T 14-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 LH59_03755 71f21e902dfceb1ee4a8f83b442f3f3f 703 SUPERFAMILY SSF50447 255 407 3.3E-35 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily LH59_03755 71f21e902dfceb1ee4a8f83b442f3f3f 703 Pfam PF03144 Elongation factor Tu domain 2 329 396 3.2E-17 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 LH59_26200 5ac5c02b367efdc51bbe8409bc04aaa7 235 Gene3D G3DSA:1.20.120.530 94 235 4.3E-26 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_26200 5ac5c02b367efdc51bbe8409bc04aaa7 235 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 75 2.3E-22 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_26200 5ac5c02b367efdc51bbe8409bc04aaa7 235 SUPERFAMILY SSF48008 95 230 2.09E-24 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_26200 5ac5c02b367efdc51bbe8409bc04aaa7 235 SMART SM00895 99 225 1.1E-19 T 14-10-2018 IPR011711 GntR, C-terminal LH59_26200 5ac5c02b367efdc51bbe8409bc04aaa7 235 SMART SM00345 16 75 2.1E-21 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_26200 5ac5c02b367efdc51bbe8409bc04aaa7 235 Gene3D G3DSA:1.10.10.10 4 75 9.3E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_26200 5ac5c02b367efdc51bbe8409bc04aaa7 235 Pfam PF07729 FCD domain 100 223 1.2E-22 T 14-10-2018 IPR011711 GntR, C-terminal LH59_26200 5ac5c02b367efdc51bbe8409bc04aaa7 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 65 2.7E-10 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_26200 5ac5c02b367efdc51bbe8409bc04aaa7 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 49 2.7E-10 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_26200 5ac5c02b367efdc51bbe8409bc04aaa7 235 SUPERFAMILY SSF46785 7 79 1.71E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_07670 5518c92c962f0b022a722ec11088d8bb 341 Gene3D G3DSA:3.40.190.150 42 329 3.8E-104 T 14-10-2018 LH59_07670 5518c92c962f0b022a722ec11088d8bb 341 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 61 335 3.6E-79 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_07670 5518c92c962f0b022a722ec11088d8bb 341 SUPERFAMILY SSF53850 125 299 6.88E-9 T 14-10-2018 LH59_07670 5518c92c962f0b022a722ec11088d8bb 341 PIRSF PIRSF017082 6 339 4.5E-76 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_07670 5518c92c962f0b022a722ec11088d8bb 341 Gene3D G3DSA:3.40.190.10 140 263 3.8E-104 T 14-10-2018 LH59_02945 b3fc0dc9774a77f5f56e14ffa69f0f6c 285 Gene3D G3DSA:1.10.12.10 227 285 1.6E-19 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal LH59_02945 b3fc0dc9774a77f5f56e14ffa69f0f6c 285 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 125 145 - T 14-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 LH59_02945 b3fc0dc9774a77f5f56e14ffa69f0f6c 285 SUPERFAMILY SSF52096 25 284 7.3E-74 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily LH59_02945 b3fc0dc9774a77f5f56e14ffa69f0f6c 285 Gene3D G3DSA:3.90.226.10 14 226 4.4E-63 T 14-10-2018 LH59_02945 b3fc0dc9774a77f5f56e14ffa69f0f6c 285 Pfam PF00378 Enoyl-CoA hydratase/isomerase 33 284 4.2E-41 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 LH59_22690 301c6592cc95838601913f82ef422068 471 Gene3D G3DSA:3.40.50.720 1 111 2.5E-32 T 14-10-2018 LH59_22690 301c6592cc95838601913f82ef422068 471 Gene3D G3DSA:3.30.160.110 113 147 9.1E-17 T 14-10-2018 LH59_22690 301c6592cc95838601913f82ef422068 471 SUPERFAMILY SSF51735 1 112 3.61E-25 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_22690 301c6592cc95838601913f82ef422068 471 Gene3D G3DSA:3.40.1010.10 214 332 1.0E-44 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 LH59_22690 301c6592cc95838601913f82ef422068 471 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 216 451 3.2E-90 T 14-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 LH59_22690 301c6592cc95838601913f82ef422068 471 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 297 330 - T 14-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 LH59_22690 301c6592cc95838601913f82ef422068 471 SUPERFAMILY SSF53790 214 458 1.7E-78 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 LH59_22690 301c6592cc95838601913f82ef422068 471 Hamap MF_01646 Siroheme synthase [cysG]. 1 461 49.232 T 14-10-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 LH59_22690 301c6592cc95838601913f82ef422068 471 Pfam PF14824 Sirohaem biosynthesis protein central 124 145 1.1E-6 T 14-10-2018 IPR028281 Siroheme synthase, central domain KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 LH59_22690 301c6592cc95838601913f82ef422068 471 Pfam PF10414 Sirohaem synthase dimerisation region 150 207 1.1E-15 T 14-10-2018 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 LH59_22690 301c6592cc95838601913f82ef422068 471 Gene3D G3DSA:3.30.950.10 333 469 3.6E-49 T 14-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 LH59_22690 301c6592cc95838601913f82ef422068 471 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 4 207 2.2E-71 T 14-10-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 LH59_22690 301c6592cc95838601913f82ef422068 471 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 221 235 - T 14-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 LH59_22690 301c6592cc95838601913f82ef422068 471 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 218 428 5.6E-51 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 LH59_22690 301c6592cc95838601913f82ef422068 471 PIRSF PIRSF036426 1 468 5.6E-193 T 14-10-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 LH59_22690 301c6592cc95838601913f82ef422068 471 SUPERFAMILY SSF75615 114 209 1.19E-23 T 14-10-2018 LH59_22690 301c6592cc95838601913f82ef422068 471 Pfam PF13241 Putative NAD(P)-binding 6 115 1.8E-25 T 14-10-2018 LH59_12070 47e0f41646842fd5aeda4cec7bf8eeef 263 Gene3D G3DSA:3.30.750.70 71 131 2.4E-5 T 14-10-2018 LH59_12070 47e0f41646842fd5aeda4cec7bf8eeef 263 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 14-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 LH59_12070 47e0f41646842fd5aeda4cec7bf8eeef 263 Pfam PF08220 DeoR-like helix-turn-helix domain 6 61 8.1E-18 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 LH59_12070 47e0f41646842fd5aeda4cec7bf8eeef 263 SUPERFAMILY SSF46785 3 59 5.12E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_12070 47e0f41646842fd5aeda4cec7bf8eeef 263 Gene3D G3DSA:1.10.10.10 1 69 9.7E-7 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_12070 47e0f41646842fd5aeda4cec7bf8eeef 263 SMART SM01134 73 234 1.3E-72 T 14-10-2018 LH59_12070 47e0f41646842fd5aeda4cec7bf8eeef 263 SMART SM00420 6 58 1.0E-18 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 LH59_12070 47e0f41646842fd5aeda4cec7bf8eeef 263 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 1.5E-9 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 LH59_12070 47e0f41646842fd5aeda4cec7bf8eeef 263 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 1.5E-9 T 14-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 LH59_12070 47e0f41646842fd5aeda4cec7bf8eeef 263 SUPERFAMILY SSF100950 77 234 2.09E-26 T 14-10-2018 IPR037171 NagB/RpiA transferase-like LH59_12070 47e0f41646842fd5aeda4cec7bf8eeef 263 Pfam PF00455 DeoR C terminal sensor domain 75 232 1.5E-53 T 14-10-2018 IPR014036 DeoR C-terminal sensor domain LH59_02630 461a7a4286489439912d83346fd62b38 302 Pfam PF02687 FtsX-like permease family 206 299 6.7E-6 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 LH59_02630 461a7a4286489439912d83346fd62b38 302 PIRSF PIRSF003097 2 302 1.1E-53 T 14-10-2018 IPR004513 Cell division protein FtsX GO:0016021 LH59_06470 7cdeabc6d691ee9adda30d253f298b83 236 Gene3D G3DSA:3.30.950.10 122 236 8.5E-44 T 14-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 LH59_06470 7cdeabc6d691ee9adda30d253f298b83 236 PIRSF PIRSF005917 1 232 2.0E-46 T 14-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 LH59_06470 7cdeabc6d691ee9adda30d253f298b83 236 SUPERFAMILY SSF53790 3 232 1.57E-64 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 LH59_06470 7cdeabc6d691ee9adda30d253f298b83 236 Gene3D G3DSA:3.40.1010.10 2 121 8.7E-39 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 LH59_06470 7cdeabc6d691ee9adda30d253f298b83 236 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 7 214 2.0E-10 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 LH59_09395 5f28fa707873917bee747ef565965a8e 218 SUPERFAMILY SSF46894 145 204 1.29E-17 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LH59_09395 5f28fa707873917bee747ef565965a8e 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 2.9E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_09395 5f28fa707873917bee747ef565965a8e 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 2.9E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_09395 5f28fa707873917bee747ef565965a8e 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 2.9E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_09395 5f28fa707873917bee747ef565965a8e 218 SMART SM00421 146 203 6.3E-22 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_09395 5f28fa707873917bee747ef565965a8e 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 163 190 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_09395 5f28fa707873917bee747ef565965a8e 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 201 8.8E-19 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_09395 5f28fa707873917bee747ef565965a8e 218 Gene3D G3DSA:1.10.10.10 97 215 5.9E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_09345 0fb6c9a97ff39986bcf7248be792e5bf 239 SMART SM00862 161 237 1.5E-11 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_09345 0fb6c9a97ff39986bcf7248be792e5bf 239 Gene3D G3DSA:1.10.10.10 147 239 8.0E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_09345 0fb6c9a97ff39986bcf7248be792e5bf 239 Pfam PF00486 Transcriptional regulatory protein, C terminal 162 237 5.5E-10 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_09345 0fb6c9a97ff39986bcf7248be792e5bf 239 Pfam PF00072 Response regulator receiver domain 12 119 2.0E-18 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_09345 0fb6c9a97ff39986bcf7248be792e5bf 239 Gene3D G3DSA:3.40.50.2300 8 145 1.4E-25 T 14-10-2018 LH59_09345 0fb6c9a97ff39986bcf7248be792e5bf 239 SUPERFAMILY SSF52172 11 134 6.4E-30 T 14-10-2018 IPR011006 CheY-like superfamily LH59_09345 0fb6c9a97ff39986bcf7248be792e5bf 239 SMART SM00448 8 119 1.0E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_09345 0fb6c9a97ff39986bcf7248be792e5bf 239 SUPERFAMILY SSF46894 155 238 1.7E-12 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LH59_07370 7d68393cdc27fcb40c1337c60ee2c9e3 563 Gene3D G3DSA:3.30.70.1450 296 375 3.0E-6 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 LH59_07370 7d68393cdc27fcb40c1337c60ee2c9e3 563 SUPERFAMILY SSF116726 291 377 6.02E-8 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 LH59_07370 7d68393cdc27fcb40c1337c60ee2c9e3 563 TIGRFAM TIGR03802 Asp_Ala_antiprt: aspartate-alanine antiporter 2 562 6.4E-198 T 14-10-2018 IPR022457 Aspartate-alanine antiporter GO:0005215|GO:0016020 LH59_07370 7d68393cdc27fcb40c1337c60ee2c9e3 563 Pfam PF06826 Predicted Permease Membrane Region 392 560 1.0E-40 T 14-10-2018 IPR006512 YidE/YbjL duplication LH59_07370 7d68393cdc27fcb40c1337c60ee2c9e3 563 Pfam PF06826 Predicted Permease Membrane Region 15 175 3.1E-37 T 14-10-2018 IPR006512 YidE/YbjL duplication LH59_07370 7d68393cdc27fcb40c1337c60ee2c9e3 563 TIGRFAM TIGR01625 YidE_YbjL_dupl: AspT/YidE/YbjL antiporter duplication domain 396 546 2.6E-25 T 14-10-2018 IPR006512 YidE/YbjL duplication LH59_07370 7d68393cdc27fcb40c1337c60ee2c9e3 563 Pfam PF02080 TrkA-C domain 226 278 1.8E-8 T 14-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 LH59_07370 7d68393cdc27fcb40c1337c60ee2c9e3 563 Pfam PF02080 TrkA-C domain 304 372 2.3E-6 T 14-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 LH59_07370 7d68393cdc27fcb40c1337c60ee2c9e3 563 Gene3D G3DSA:3.30.70.1450 222 287 3.6E-7 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 LH59_07370 7d68393cdc27fcb40c1337c60ee2c9e3 563 SUPERFAMILY SSF116726 223 279 1.09E-7 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 LH59_21365 930e730605904a90c576c19abbaf6333 302 Gene3D G3DSA:1.10.10.10 6 93 3.8E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_21365 930e730605904a90c576c19abbaf6333 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 1.7E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_21365 930e730605904a90c576c19abbaf6333 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 1.7E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_21365 930e730605904a90c576c19abbaf6333 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 1.7E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_21365 930e730605904a90c576c19abbaf6333 302 SUPERFAMILY SSF53850 97 301 5.88E-37 T 14-10-2018 LH59_21365 930e730605904a90c576c19abbaf6333 302 Gene3D G3DSA:3.40.190.10 170 274 3.3E-56 T 14-10-2018 LH59_21365 930e730605904a90c576c19abbaf6333 302 Pfam PF03466 LysR substrate binding domain 97 298 2.4E-40 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_21365 930e730605904a90c576c19abbaf6333 302 SUPERFAMILY SSF46785 5 116 1.4E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_21365 930e730605904a90c576c19abbaf6333 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 68 6.1E-21 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_21365 930e730605904a90c576c19abbaf6333 302 Gene3D G3DSA:3.40.190.10 99 285 3.3E-56 T 14-10-2018 LH59_20955 e6cefe441adfbafb2957cc47eed78aac 464 SMART SM00345 28 87 7.5E-11 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_20955 e6cefe441adfbafb2957cc47eed78aac 464 SUPERFAMILY SSF53383 95 454 1.71E-66 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_20955 e6cefe441adfbafb2957cc47eed78aac 464 Pfam PF00392 Bacterial regulatory proteins, gntR family 25 87 9.9E-12 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_20955 e6cefe441adfbafb2957cc47eed78aac 464 Gene3D G3DSA:3.90.1150.10 117 449 4.8E-57 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_20955 e6cefe441adfbafb2957cc47eed78aac 464 SUPERFAMILY SSF46785 21 100 1.5E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_20955 e6cefe441adfbafb2957cc47eed78aac 464 Gene3D G3DSA:1.10.10.10 18 88 1.2E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_20955 e6cefe441adfbafb2957cc47eed78aac 464 Pfam PF00155 Aminotransferase class I and II 129 448 1.3E-16 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LH59_20955 e6cefe441adfbafb2957cc47eed78aac 464 Gene3D G3DSA:3.40.640.10 136 351 4.8E-57 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_22420 442168c5035266e1c9fc24926cf128dd 192 SMART SM00072 9 190 7.5E-4 T 14-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit LH59_22420 442168c5035266e1c9fc24926cf128dd 192 SUPERFAMILY SSF52540 11 188 2.79E-30 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_22420 442168c5035266e1c9fc24926cf128dd 192 Gene3D G3DSA:3.30.63.10 44 98 7.0E-11 T 14-10-2018 LH59_22420 442168c5035266e1c9fc24926cf128dd 192 Gene3D G3DSA:3.40.50.300 15 185 7.0E-11 T 14-10-2018 LH59_22420 442168c5035266e1c9fc24926cf128dd 192 TIGRFAM TIGR02322 phosphon_PhnN: phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN 11 186 5.2E-60 T 14-10-2018 IPR012699 Ribose 1,5-bisphosphate phosphokinase PhnN GO:0006015|GO:0033863 KEGG: 00030+2.7.4.23|MetaCyc: PWY-7805|MetaCyc: PWY-7807 LH59_22420 442168c5035266e1c9fc24926cf128dd 192 Hamap MF_00836 Ribose 1,5-bisphosphate phosphokinase PhnN [phnN]. 9 187 34.437 T 14-10-2018 IPR012699 Ribose 1,5-bisphosphate phosphokinase PhnN GO:0006015|GO:0033863 KEGG: 00030+2.7.4.23|MetaCyc: PWY-7805|MetaCyc: PWY-7807 LH59_12785 6062b8e446560419660b382df691493c 347 Gene3D G3DSA:3.40.190.10 34 307 1.2E-126 T 14-10-2018 LH59_12785 6062b8e446560419660b382df691493c 347 Pfam PF13343 Bacterial extracellular solute-binding protein 79 305 3.2E-18 T 14-10-2018 LH59_12785 6062b8e446560419660b382df691493c 347 PIRSF PIRSF002825 4 347 1.6E-86 T 14-10-2018 IPR026045 Ferric binding protein LH59_12785 6062b8e446560419660b382df691493c 347 SUPERFAMILY SSF53850 30 344 2.5E-74 T 14-10-2018 LH59_12785 6062b8e446560419660b382df691493c 347 Gene3D G3DSA:3.40.190.10 127 340 1.2E-126 T 14-10-2018 LH59_28130 c71c025a07cc3184c414d4caff2e4d4e 68 Pfam PF00313 'Cold-shock' DNA-binding domain 4 66 6.9E-31 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 LH59_28130 c71c025a07cc3184c414d4caff2e4d4e 68 SMART SM00357 4 68 7.8E-32 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 LH59_28130 c71c025a07cc3184c414d4caff2e4d4e 68 ProSitePatterns PS00352 'Cold-shock' domain signature. 16 35 - T 14-10-2018 IPR019844 Cold-shock conserved site LH59_28130 c71c025a07cc3184c414d4caff2e4d4e 68 PIRSF PIRSF002599 1 68 1.1E-26 T 14-10-2018 IPR012156 Cold shock, CspA GO:0003676 LH59_28130 c71c025a07cc3184c414d4caff2e4d4e 68 Gene3D G3DSA:2.40.50.140 2 66 2.3E-30 T 14-10-2018 LH59_28130 c71c025a07cc3184c414d4caff2e4d4e 68 PRINTS PR00050 Cold shock protein signature 41 59 2.6E-18 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 LH59_28130 c71c025a07cc3184c414d4caff2e4d4e 68 PRINTS PR00050 Cold shock protein signature 5 20 2.6E-18 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 LH59_28130 c71c025a07cc3184c414d4caff2e4d4e 68 PRINTS PR00050 Cold shock protein signature 26 35 2.6E-18 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 LH59_28130 c71c025a07cc3184c414d4caff2e4d4e 68 SUPERFAMILY SSF50249 3 67 4.5E-25 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_25405 e261e8385d166a264cc6e98e213ac1ae 481 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 270 281 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 LH59_25405 e261e8385d166a264cc6e98e213ac1ae 481 Gene3D G3DSA:3.40.605.10 13 468 1.8E-170 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 LH59_25405 e261e8385d166a264cc6e98e213ac1ae 481 SUPERFAMILY SSF53720 3 476 9.03E-160 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 LH59_25405 e261e8385d166a264cc6e98e213ac1ae 481 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 242 249 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 LH59_25405 e261e8385d166a264cc6e98e213ac1ae 481 Gene3D G3DSA:3.40.309.10 250 444 1.8E-170 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 LH59_25405 e261e8385d166a264cc6e98e213ac1ae 481 Pfam PF00171 Aldehyde dehydrogenase family 5 469 7.5E-168 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 LH59_02625 475d13ceeb662237ebc44ad7786d6b40 258 SUPERFAMILY SSF64438 23 169 1.56E-49 T 14-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic LH59_02625 475d13ceeb662237ebc44ad7786d6b40 258 Pfam PF03975 CheD chemotactic sensory transduction 65 167 3.2E-31 T 14-10-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 LH59_02625 475d13ceeb662237ebc44ad7786d6b40 258 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 18 171 29.52 T 14-10-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 LH59_02625 475d13ceeb662237ebc44ad7786d6b40 258 Gene3D G3DSA:3.30.1330.200 20 178 2.4E-50 T 14-10-2018 IPR038592 CheD-like superfamily LH59_17175 5abeafa2c0f18dd7e3ffea5ad88bfc9a 170 Gene3D G3DSA:1.20.1280.20 83 169 3.9E-18 T 14-10-2018 IPR036386 HscB, C-terminal domain superfamily GO:0051259 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 LH59_17175 5abeafa2c0f18dd7e3ffea5ad88bfc9a 170 TIGRFAM TIGR00714 hscB: Fe-S protein assembly co-chaperone HscB 16 167 7.0E-28 T 14-10-2018 IPR004640 Co-chaperone Hsc20 GO:0001671|GO:0051087|GO:0097428 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 LH59_17175 5abeafa2c0f18dd7e3ffea5ad88bfc9a 170 SMART SM00271 4 69 1.5E-4 T 14-10-2018 IPR001623 DnaJ domain LH59_17175 5abeafa2c0f18dd7e3ffea5ad88bfc9a 170 SUPERFAMILY SSF47144 80 168 1.57E-18 T 14-10-2018 IPR036386 HscB, C-terminal domain superfamily GO:0051259 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 LH59_17175 5abeafa2c0f18dd7e3ffea5ad88bfc9a 170 Pfam PF07743 HSCB C-terminal oligomerisation domain 90 163 1.9E-14 T 14-10-2018 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 LH59_17175 5abeafa2c0f18dd7e3ffea5ad88bfc9a 170 SUPERFAMILY SSF46565 5 75 8.5E-17 T 14-10-2018 IPR036869 Chaperone J-domain superfamily LH59_17175 5abeafa2c0f18dd7e3ffea5ad88bfc9a 170 Hamap MF_00682 Co-chaperone protein HscB [hscB]. 4 170 20.932 T 14-10-2018 IPR004640 Co-chaperone Hsc20 GO:0001671|GO:0051087|GO:0097428 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 LH59_17175 5abeafa2c0f18dd7e3ffea5ad88bfc9a 170 Gene3D G3DSA:1.10.287.110 5 82 2.1E-21 T 14-10-2018 IPR036869 Chaperone J-domain superfamily LH59_16430 d631dffec858088279d3239149cee959 253 Gene3D G3DSA:3.90.1200.10 91 253 4.4E-40 T 14-10-2018 LH59_16430 d631dffec858088279d3239149cee959 253 Pfam PF01636 Phosphotransferase enzyme family 24 225 2.9E-24 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase LH59_16430 d631dffec858088279d3239149cee959 253 SUPERFAMILY SSF56112 9 252 4.25E-37 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily LH59_16430 d631dffec858088279d3239149cee959 253 PIRSF PIRSF000706 1 253 2.9E-62 T 14-10-2018 IPR024165 Aminoglycoside 3-phosphotransferase GO:0005524|GO:0016773|GO:0046677 LH59_16430 d631dffec858088279d3239149cee959 253 Gene3D G3DSA:3.30.200.20 1 85 8.8E-21 T 14-10-2018 LH59_22885 7939a8865e4323f187f8955a5dfa9bc2 160 Pfam PF02391 MoaE protein 5 119 1.4E-31 T 14-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 LH59_22885 7939a8865e4323f187f8955a5dfa9bc2 160 SUPERFAMILY SSF54690 3 149 6.28E-45 T 14-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 LH59_22885 7939a8865e4323f187f8955a5dfa9bc2 160 Gene3D G3DSA:3.90.1170.40 1 149 1.7E-43 T 14-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 LH59_11050 1623f6f561dd2e8d88ad7cb92e0f4cb5 191 Gene3D G3DSA:3.40.30.10 49 177 6.3E-19 T 14-10-2018 LH59_11050 1623f6f561dd2e8d88ad7cb92e0f4cb5 191 Pfam PF00578 AhpC/TSA family 50 130 3.6E-14 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 LH59_11050 1623f6f561dd2e8d88ad7cb92e0f4cb5 191 SUPERFAMILY SSF52833 48 145 5.51E-19 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_20460 43dd02653bc081f5d34e3690c540c8c5 335 Pfam PF09084 NMT1/THI5 like 53 272 6.8E-23 T 14-10-2018 IPR015168 SsuA/THI5-like LH59_20460 43dd02653bc081f5d34e3690c540c8c5 335 Gene3D G3DSA:3.40.190.10 36 131 2.8E-10 T 14-10-2018 LH59_20460 43dd02653bc081f5d34e3690c540c8c5 335 Gene3D G3DSA:3.40.190.10 132 220 5.2E-17 T 14-10-2018 LH59_20460 43dd02653bc081f5d34e3690c540c8c5 335 Gene3D G3DSA:3.40.190.10 230 334 2.2E-6 T 14-10-2018 LH59_20460 43dd02653bc081f5d34e3690c540c8c5 335 SUPERFAMILY SSF53850 40 273 1.96E-36 T 14-10-2018 LH59_23940 e2a2afde8e9d6d3139447057ef35ddca 327 SUPERFAMILY SSF52317 11 204 8.89E-44 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_23940 e2a2afde8e9d6d3139447057ef35ddca 327 SUPERFAMILY SSF46689 274 322 1.39E-5 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_23940 e2a2afde8e9d6d3139447057ef35ddca 327 Gene3D G3DSA:1.10.10.60 223 323 2.0E-21 T 14-10-2018 LH59_23940 e2a2afde8e9d6d3139447057ef35ddca 327 Pfam PF12833 Helix-turn-helix domain 244 319 7.6E-18 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_23940 e2a2afde8e9d6d3139447057ef35ddca 327 SMART SM00342 237 319 1.2E-18 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_23940 e2a2afde8e9d6d3139447057ef35ddca 327 Gene3D G3DSA:3.40.50.880 8 213 8.3E-59 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_23940 e2a2afde8e9d6d3139447057ef35ddca 327 Pfam PF01965 DJ-1/PfpI family 13 185 1.4E-22 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 LH59_23940 e2a2afde8e9d6d3139447057ef35ddca 327 SUPERFAMILY SSF46689 225 270 1.25E-6 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_10585 a0b072aa123be6c198485ee958889f75 699 SUPERFAMILY SSF56935 28 699 3.97E-125 T 14-10-2018 LH59_10585 a0b072aa123be6c198485ee958889f75 699 Gene3D G3DSA:2.170.130.10 46 164 1.6E-31 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily LH59_10585 a0b072aa123be6c198485ee958889f75 699 Pfam PF00593 TonB dependent receptor 226 698 3.2E-60 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_10585 a0b072aa123be6c198485ee958889f75 699 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 682 699 - T 14-10-2018 IPR010917 TonB-dependent receptor, conserved site LH59_10585 a0b072aa123be6c198485ee958889f75 699 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 63 699 5.7E-108 T 14-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 LH59_10585 a0b072aa123be6c198485ee958889f75 699 Gene3D G3DSA:2.40.170.20 165 699 6.5E-116 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_10585 a0b072aa123be6c198485ee958889f75 699 Pfam PF07715 TonB-dependent Receptor Plug Domain 62 155 5.1E-18 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_17830 a51ff6f878ce5e3be979cde5a2bc28d6 427 Gene3D G3DSA:1.20.1250.20 229 425 2.6E-21 T 14-10-2018 LH59_17830 a51ff6f878ce5e3be979cde5a2bc28d6 427 Gene3D G3DSA:1.20.1250.20 11 209 2.8E-25 T 14-10-2018 LH59_17830 a51ff6f878ce5e3be979cde5a2bc28d6 427 Pfam PF07690 Major Facilitator Superfamily 25 351 6.4E-33 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_17830 a51ff6f878ce5e3be979cde5a2bc28d6 427 SUPERFAMILY SSF103473 7 421 7.32E-58 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_16390 20e18d5ee520e14d6222827efce306b6 391 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 219 380 1.9E-32 T 14-10-2018 IPR000160 GGDEF domain LH59_16390 20e18d5ee520e14d6222827efce306b6 391 SUPERFAMILY SSF55073 226 379 1.88E-37 T 14-10-2018 IPR029787 Nucleotide cyclase LH59_16390 20e18d5ee520e14d6222827efce306b6 391 Pfam PF00990 Diguanylate cyclase, GGDEF domain 222 378 2.2E-33 T 14-10-2018 IPR000160 GGDEF domain LH59_16390 20e18d5ee520e14d6222827efce306b6 391 SMART SM00267 210 382 1.3E-36 T 14-10-2018 IPR000160 GGDEF domain LH59_16390 20e18d5ee520e14d6222827efce306b6 391 Gene3D G3DSA:3.30.70.270 210 383 3.4E-44 T 14-10-2018 LH59_22965 8b2cf82ab7c7cdc8fdc436ac92d40f16 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 4.4E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_22965 8b2cf82ab7c7cdc8fdc436ac92d40f16 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 4.4E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_22965 8b2cf82ab7c7cdc8fdc436ac92d40f16 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 4.4E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_22965 8b2cf82ab7c7cdc8fdc436ac92d40f16 308 Gene3D G3DSA:3.40.190.10 91 294 3.4E-64 T 14-10-2018 LH59_22965 8b2cf82ab7c7cdc8fdc436ac92d40f16 308 Gene3D G3DSA:3.40.190.10 167 276 3.4E-64 T 14-10-2018 LH59_22965 8b2cf82ab7c7cdc8fdc436ac92d40f16 308 Pfam PF03466 LysR substrate binding domain 91 300 3.2E-42 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_22965 8b2cf82ab7c7cdc8fdc436ac92d40f16 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 3.0E-21 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_22965 8b2cf82ab7c7cdc8fdc436ac92d40f16 308 SUPERFAMILY SSF53850 91 302 1.09E-37 T 14-10-2018 LH59_22965 8b2cf82ab7c7cdc8fdc436ac92d40f16 308 SUPERFAMILY SSF46785 5 87 3.55E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_22965 8b2cf82ab7c7cdc8fdc436ac92d40f16 308 Gene3D G3DSA:1.10.10.10 4 89 3.5E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_24155 65cc19b2654fd00f068419aee42e01c0 399 Pfam PF00155 Aminotransferase class I and II 31 390 8.2E-69 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LH59_24155 65cc19b2654fd00f068419aee42e01c0 399 Gene3D G3DSA:3.90.1150.10 23 390 2.5E-128 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_24155 65cc19b2654fd00f068419aee42e01c0 399 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 236 249 - T 14-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 LH59_24155 65cc19b2654fd00f068419aee42e01c0 399 Gene3D G3DSA:3.40.640.10 61 286 2.5E-128 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_24155 65cc19b2654fd00f068419aee42e01c0 399 SUPERFAMILY SSF53383 2 392 1.18E-107 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_12340 4240dadcd7228a9ce188b1928bc88526 430 PIRSF PIRSF005353 1 429 2.6E-176 T 14-10-2018 IPR026033 Purine permease PbuG-like LH59_12340 4240dadcd7228a9ce188b1928bc88526 430 Pfam PF00860 Permease family 17 390 1.6E-52 T 14-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 LH59_09180 9eb54fea229062fd182fca98884c0acf 386 SMART SM00564 107 138 94.0 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat LH59_09180 9eb54fea229062fd182fca98884c0acf 386 SMART SM00564 191 223 270.0 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat LH59_09180 9eb54fea229062fd182fca98884c0acf 386 SMART SM00564 147 178 0.0014 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat LH59_09180 9eb54fea229062fd182fca98884c0acf 386 SMART SM00564 68 99 22.0 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat LH59_09180 9eb54fea229062fd182fca98884c0acf 386 SMART SM00564 323 354 0.26 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat LH59_09180 9eb54fea229062fd182fca98884c0acf 386 Pfam PF13360 PQQ-like domain 81 312 2.6E-48 T 14-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat LH59_09180 9eb54fea229062fd182fca98884c0acf 386 TIGRFAM TIGR03300 assembly_YfgL: outer membrane assembly lipoprotein YfgL 12 382 6.4E-125 T 14-10-2018 IPR017687 Outer membrane protein assembly factor BamB LH59_09180 9eb54fea229062fd182fca98884c0acf 386 SUPERFAMILY SSF50998 30 376 3.48E-69 T 14-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily LH59_09180 9eb54fea229062fd182fca98884c0acf 386 Gene3D G3DSA:2.130.10.10 28 384 6.1E-80 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 LH59_09180 9eb54fea229062fd182fca98884c0acf 386 Hamap MF_00923 Outer membrane protein assembly factor BamB [bamB]. 8 385 37.505 T 14-10-2018 IPR017687 Outer membrane protein assembly factor BamB LH59_05000 4b683ef88b9a4e37e09537a770203b26 516 SUPERFAMILY SSF158472 252 300 2.35E-5 T 14-10-2018 LH59_05000 4b683ef88b9a4e37e09537a770203b26 516 Pfam PF00672 HAMP domain 252 299 4.3E-9 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_05000 4b683ef88b9a4e37e09537a770203b26 516 Gene3D G3DSA:3.30.565.10 370 515 5.0E-29 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_05000 4b683ef88b9a4e37e09537a770203b26 516 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 405 512 1.5E-14 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_05000 4b683ef88b9a4e37e09537a770203b26 516 SUPERFAMILY SSF47384 287 358 2.55E-7 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 LH59_05000 4b683ef88b9a4e37e09537a770203b26 516 PRINTS PR00344 Bacterial sensor protein C-terminal signature 440 454 2.1E-7 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_05000 4b683ef88b9a4e37e09537a770203b26 516 PRINTS PR00344 Bacterial sensor protein C-terminal signature 498 511 2.1E-7 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_05000 4b683ef88b9a4e37e09537a770203b26 516 PRINTS PR00344 Bacterial sensor protein C-terminal signature 474 492 2.1E-7 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_05000 4b683ef88b9a4e37e09537a770203b26 516 SMART SM00387 405 514 7.2E-26 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_05000 4b683ef88b9a4e37e09537a770203b26 516 Gene3D G3DSA:1.10.287.130 252 357 1.9E-14 T 14-10-2018 LH59_05000 4b683ef88b9a4e37e09537a770203b26 516 SUPERFAMILY SSF55874 389 511 1.83E-28 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_05000 4b683ef88b9a4e37e09537a770203b26 516 SMART SM00304 252 303 2.9E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_02510 d821900576dd7e5a133f8ce4d83ffa5e 162 Gene3D G3DSA:3.40.50.620 10 162 9.1E-31 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LH59_02510 d821900576dd7e5a133f8ce4d83ffa5e 162 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 30 91 9.6E-13 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 LH59_02510 d821900576dd7e5a133f8ce4d83ffa5e 162 Pfam PF01467 Cytidylyltransferase-like 32 124 3.3E-13 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 LH59_02510 d821900576dd7e5a133f8ce4d83ffa5e 162 SUPERFAMILY SSF52374 28 158 1.22E-21 T 14-10-2018 LH59_01225 ea6ac4d74cbd696627a2893fc03a145a 339 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 128 4.4E-11 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 LH59_01225 ea6ac4d74cbd696627a2893fc03a145a 339 SUPERFAMILY SSF50129 1 165 1.67E-36 T 14-10-2018 IPR011032 GroES-like superfamily LH59_01225 ea6ac4d74cbd696627a2893fc03a145a 339 Gene3D G3DSA:3.40.50.720 142 285 3.1E-101 T 14-10-2018 LH59_01225 ea6ac4d74cbd696627a2893fc03a145a 339 Gene3D G3DSA:3.90.180.10 23 328 3.1E-101 T 14-10-2018 LH59_01225 ea6ac4d74cbd696627a2893fc03a145a 339 SMART SM00829 11 335 1.1E-30 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 LH59_01225 ea6ac4d74cbd696627a2893fc03a145a 339 Pfam PF00107 Zinc-binding dehydrogenase 171 298 5.7E-29 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 LH59_01225 ea6ac4d74cbd696627a2893fc03a145a 339 SUPERFAMILY SSF51735 136 312 6.35E-42 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_17665 67d50accf5fa43279acc1e06801cd4ee 763 Gene3D G3DSA:1.10.10.160 110 182 2.3E-92 T 14-10-2018 IPR013986 DExx box DNA helicase domain superfamily LH59_17665 67d50accf5fa43279acc1e06801cd4ee 763 Pfam PF00580 UvrD/REP helicase N-terminal domain 6 266 8.0E-74 T 14-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 LH59_17665 67d50accf5fa43279acc1e06801cd4ee 763 SUPERFAMILY SSF52540 3 657 1.69E-176 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_17665 67d50accf5fa43279acc1e06801cd4ee 763 Gene3D G3DSA:3.40.50.300 6 267 2.3E-92 T 14-10-2018 LH59_17665 67d50accf5fa43279acc1e06801cd4ee 763 Pfam PF13361 UvrD-like helicase C-terminal domain 272 632 3.2E-71 T 14-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 LH59_05130 9d045d91f2bdf95bac561933bc7f489e 416 Pfam PF07690 Major Facilitator Superfamily 24 302 2.0E-13 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_05130 9d045d91f2bdf95bac561933bc7f489e 416 Gene3D G3DSA:1.20.1250.20 10 207 1.3E-9 T 14-10-2018 LH59_05130 9d045d91f2bdf95bac561933bc7f489e 416 Gene3D G3DSA:1.20.1250.20 216 409 7.9E-10 T 14-10-2018 LH59_05130 9d045d91f2bdf95bac561933bc7f489e 416 SUPERFAMILY SSF103473 10 410 3.4E-30 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_04935 a302fe40bf76b6be71d3754950db2cb9 557 Pfam PF00005 ABC transporter 343 476 2.6E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_04935 a302fe40bf76b6be71d3754950db2cb9 557 Gene3D G3DSA:3.40.50.300 1 288 6.7E-81 T 14-10-2018 LH59_04935 a302fe40bf76b6be71d3754950db2cb9 557 SUPERFAMILY SSF52540 12 239 8.27E-47 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_04935 a302fe40bf76b6be71d3754950db2cb9 557 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 2 556 2.1E-290 T 14-10-2018 IPR022374 Energy-dependent translational throttle protein EttA GO:0045900 LH59_04935 a302fe40bf76b6be71d3754950db2cb9 557 SUPERFAMILY SSF52540 305 533 2.92E-49 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_04935 a302fe40bf76b6be71d3754950db2cb9 557 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_04935 a302fe40bf76b6be71d3754950db2cb9 557 Pfam PF00005 ABC transporter 22 194 1.6E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_04935 a302fe40bf76b6be71d3754950db2cb9 557 SMART SM00382 351 529 2.2E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_04935 a302fe40bf76b6be71d3754950db2cb9 557 SMART SM00382 31 245 3.0E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_04935 a302fe40bf76b6be71d3754950db2cb9 557 Pfam PF12848 ABC transporter 233 309 1.2E-12 T 14-10-2018 IPR032781 ABC-transporter extension domain LH59_04935 a302fe40bf76b6be71d3754950db2cb9 557 Gene3D G3DSA:3.40.50.300 289 556 2.3E-75 T 14-10-2018 LH59_03840 e66f3cdf75c9ea7db10283ba5a4d0713 503 Pfam PF08521 Two-component sensor kinase N-terminal 19 172 3.3E-32 T 14-10-2018 IPR013727 Two-component sensor kinase, N-terminal LH59_03840 e66f3cdf75c9ea7db10283ba5a4d0713 503 SUPERFAMILY SSF47384 236 316 5.89E-15 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 LH59_03840 e66f3cdf75c9ea7db10283ba5a4d0713 503 SMART SM00387 369 486 2.4E-23 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_03840 e66f3cdf75c9ea7db10283ba5a4d0713 503 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 370 484 3.3E-15 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_03840 e66f3cdf75c9ea7db10283ba5a4d0713 503 Gene3D G3DSA:1.10.287.130 204 315 3.9E-17 T 14-10-2018 LH59_03840 e66f3cdf75c9ea7db10283ba5a4d0713 503 SMART SM00388 253 318 7.4E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_03840 e66f3cdf75c9ea7db10283ba5a4d0713 503 PRINTS PR00344 Bacterial sensor protein C-terminal signature 470 483 1.4E-6 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_03840 e66f3cdf75c9ea7db10283ba5a4d0713 503 PRINTS PR00344 Bacterial sensor protein C-terminal signature 441 459 1.4E-6 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_03840 e66f3cdf75c9ea7db10283ba5a4d0713 503 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 420 1.4E-6 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_03840 e66f3cdf75c9ea7db10283ba5a4d0713 503 Gene3D G3DSA:3.30.565.10 316 485 1.0E-24 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_03840 e66f3cdf75c9ea7db10283ba5a4d0713 503 Pfam PF00512 His Kinase A (phospho-acceptor) domain 254 315 1.5E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_03840 e66f3cdf75c9ea7db10283ba5a4d0713 503 SUPERFAMILY SSF55874 313 484 7.07E-27 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_06190 0b9a725fc4b3ba9b846b8757bebb6263 1160 SMART SM01058 494 591 4.1E-46 T 14-10-2018 IPR003711 CarD-like/TRCF domain LH59_06190 0b9a725fc4b3ba9b846b8757bebb6263 1160 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 54 1127 27.27 T 14-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 LH59_06190 0b9a725fc4b3ba9b846b8757bebb6263 1160 SUPERFAMILY SSF141259 486 563 7.72E-23 T 14-10-2018 IPR036101 CarD-like/TRCF domain superfamily LH59_06190 0b9a725fc4b3ba9b846b8757bebb6263 1160 SMART SM00490 841 925 2.3E-17 T 14-10-2018 IPR001650 Helicase, C-terminal LH59_06190 0b9a725fc4b3ba9b846b8757bebb6263 1160 Pfam PF00271 Helicase conserved C-terminal domain 820 924 3.9E-17 T 14-10-2018 IPR001650 Helicase, C-terminal LH59_06190 0b9a725fc4b3ba9b846b8757bebb6263 1160 Pfam PF00270 DEAD/DEAH box helicase 620 777 5.3E-17 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 LH59_06190 0b9a725fc4b3ba9b846b8757bebb6263 1160 SMART SM00982 1023 1123 1.9E-48 T 14-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 LH59_06190 0b9a725fc4b3ba9b846b8757bebb6263 1160 Gene3D G3DSA:3.90.1150.50 1020 1160 2.5E-39 T 14-10-2018 IPR037235 TRCF-like, C-terminal domain LH59_06190 0b9a725fc4b3ba9b846b8757bebb6263 1160 SUPERFAMILY SSF52540 364 477 3.04E-21 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_06190 0b9a725fc4b3ba9b846b8757bebb6263 1160 SUPERFAMILY SSF52540 34 360 2.12E-91 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_06190 0b9a725fc4b3ba9b846b8757bebb6263 1160 SUPERFAMILY SSF52540 538 798 3.6E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_06190 0b9a725fc4b3ba9b846b8757bebb6263 1160 Pfam PF02559 CarD-like/TRCF domain 495 590 7.0E-26 T 14-10-2018 IPR003711 CarD-like/TRCF domain LH59_06190 0b9a725fc4b3ba9b846b8757bebb6263 1160 Gene3D G3DSA:3.40.50.11180 43 353 2.7E-108 T 14-10-2018 LH59_06190 0b9a725fc4b3ba9b846b8757bebb6263 1160 Gene3D G3DSA:3.40.50.300 493 1004 6.8E-231 T 14-10-2018 LH59_06190 0b9a725fc4b3ba9b846b8757bebb6263 1160 Pfam PF03461 TRCF domain 1024 1117 1.5E-26 T 14-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 LH59_06190 0b9a725fc4b3ba9b846b8757bebb6263 1160 Gene3D G3DSA:3.40.50.300 557 796 6.8E-231 T 14-10-2018 LH59_06190 0b9a725fc4b3ba9b846b8757bebb6263 1160 SUPERFAMILY SSF52540 798 1005 3.17E-47 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_06190 0b9a725fc4b3ba9b846b8757bebb6263 1160 SUPERFAMILY SSF143517 1009 1159 1.57E-38 T 14-10-2018 IPR037235 TRCF-like, C-terminal domain LH59_06190 0b9a725fc4b3ba9b846b8757bebb6263 1160 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 168 1096 0.0 T 14-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 LH59_06190 0b9a725fc4b3ba9b846b8757bebb6263 1160 Gene3D G3DSA:3.30.2060.10 148 233 2.7E-108 T 14-10-2018 LH59_06190 0b9a725fc4b3ba9b846b8757bebb6263 1160 Gene3D G3DSA:2.30.30.840 498 556 6.8E-231 T 14-10-2018 LH59_06190 0b9a725fc4b3ba9b846b8757bebb6263 1160 Gene3D G3DSA:3.40.50.11140 366 465 1.2E-11 T 14-10-2018 LH59_06190 0b9a725fc4b3ba9b846b8757bebb6263 1160 SMART SM00487 615 805 9.8E-33 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain LH59_00965 6f6a5ca75d8ad2bfeddad655a9fcd4c3 434 Gene3D G3DSA:3.40.50.1980 35 235 8.8E-127 T 14-10-2018 LH59_00965 6f6a5ca75d8ad2bfeddad655a9fcd4c3 434 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 233 265 - T 14-10-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 LH59_00965 6f6a5ca75d8ad2bfeddad655a9fcd4c3 434 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 38 430 5.9E-160 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 LH59_00965 6f6a5ca75d8ad2bfeddad655a9fcd4c3 434 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 2 431 40.433 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 LH59_00965 6f6a5ca75d8ad2bfeddad655a9fcd4c3 434 PIRSF PIRSF000099 5 433 1.3E-157 T 14-10-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 LH59_00965 6f6a5ca75d8ad2bfeddad655a9fcd4c3 434 Pfam PF00815 Histidinol dehydrogenase 27 430 4.6E-167 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 LH59_00965 6f6a5ca75d8ad2bfeddad655a9fcd4c3 434 PRINTS PR00083 Histidinol dehydrogenase signature 36 60 8.2E-81 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 LH59_00965 6f6a5ca75d8ad2bfeddad655a9fcd4c3 434 PRINTS PR00083 Histidinol dehydrogenase signature 255 274 8.2E-81 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 LH59_00965 6f6a5ca75d8ad2bfeddad655a9fcd4c3 434 PRINTS PR00083 Histidinol dehydrogenase signature 174 200 8.2E-81 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 LH59_00965 6f6a5ca75d8ad2bfeddad655a9fcd4c3 434 PRINTS PR00083 Histidinol dehydrogenase signature 140 166 8.2E-81 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 LH59_00965 6f6a5ca75d8ad2bfeddad655a9fcd4c3 434 PRINTS PR00083 Histidinol dehydrogenase signature 233 254 8.2E-81 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 LH59_00965 6f6a5ca75d8ad2bfeddad655a9fcd4c3 434 PRINTS PR00083 Histidinol dehydrogenase signature 365 383 8.2E-81 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 LH59_00965 6f6a5ca75d8ad2bfeddad655a9fcd4c3 434 PRINTS PR00083 Histidinol dehydrogenase signature 324 349 8.2E-81 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 LH59_00965 6f6a5ca75d8ad2bfeddad655a9fcd4c3 434 PRINTS PR00083 Histidinol dehydrogenase signature 204 229 8.2E-81 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 LH59_00965 6f6a5ca75d8ad2bfeddad655a9fcd4c3 434 SUPERFAMILY SSF53720 30 431 8.44E-87 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 LH59_00965 6f6a5ca75d8ad2bfeddad655a9fcd4c3 434 Gene3D G3DSA:3.40.50.1980 237 353 8.8E-127 T 14-10-2018 LH59_11190 e4c2d6c8aa1a975fee70f669f69c580d 301 SUPERFAMILY SSF46785 2 103 1.36E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_11190 e4c2d6c8aa1a975fee70f669f69c580d 301 Gene3D G3DSA:1.10.10.10 1 82 2.3E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_11190 e4c2d6c8aa1a975fee70f669f69c580d 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 1 57 4.3E-19 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_11190 e4c2d6c8aa1a975fee70f669f69c580d 301 Pfam PF03466 LysR substrate binding domain 83 287 1.3E-31 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_11190 e4c2d6c8aa1a975fee70f669f69c580d 301 Gene3D G3DSA:3.40.190.290 85 286 2.7E-48 T 14-10-2018 LH59_11190 e4c2d6c8aa1a975fee70f669f69c580d 301 SUPERFAMILY SSF53850 84 289 7.06E-35 T 14-10-2018 LH59_04175 8a7b3537e98173e37eae4cc54a815a3c 623 Pfam PF01266 FAD dependent oxidoreductase 254 604 5.7E-27 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 LH59_04175 8a7b3537e98173e37eae4cc54a815a3c 623 SUPERFAMILY SSF51905 254 613 2.46E-22 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_04175 8a7b3537e98173e37eae4cc54a815a3c 623 Gene3D G3DSA:3.50.50.60 253 622 1.7E-68 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_04175 8a7b3537e98173e37eae4cc54a815a3c 623 Hamap MF_01102 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC [mnmC]. 9 623 21.15 T 14-10-2018 IPR023032 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC GO:0004808|GO:0008033|GO:0008168|GO:0016645|GO:0055114 MetaCyc: PWY-7892 LH59_04175 8a7b3537e98173e37eae4cc54a815a3c 623 TIGRFAM TIGR03197 MnmC_Cterm: tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal domain 254 622 1.3E-60 T 14-10-2018 IPR017610 tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal GO:0008168|GO:0016645|GO:0055114 MetaCyc: PWY-7892 LH59_04175 8a7b3537e98173e37eae4cc54a815a3c 623 Gene3D G3DSA:3.30.9.10 337 564 1.7E-68 T 14-10-2018 LH59_04175 8a7b3537e98173e37eae4cc54a815a3c 623 Pfam PF05430 S-adenosyl-L-methionine-dependent methyltransferase 117 236 2.4E-34 T 14-10-2018 IPR008471 MnmC-like methyltransferase GO:0016645|GO:0055114 MetaCyc: PWY-7892 LH59_04175 8a7b3537e98173e37eae4cc54a815a3c 623 Gene3D G3DSA:3.40.50.150 13 244 2.9E-88 T 14-10-2018 LH59_21090 1689b8af18442f212429af20af1d11d3 316 SUPERFAMILY SSF46626 64 215 1.89E-29 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_21090 1689b8af18442f212429af20af1d11d3 316 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 136 208 1.9E-13 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_21090 1689b8af18442f212429af20af1d11d3 316 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 223 296 1.9E-12 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_21090 1689b8af18442f212429af20af1d11d3 316 Pfam PF14715 N-terminal domain of cytochrome oxidase-cbb3, FixP 44 91 4.0E-19 T 14-10-2018 IPR032858 Cbb3-type cytochrome c oxidase subunit CcoP, N-terminal LH59_21090 1689b8af18442f212429af20af1d11d3 316 Gene3D G3DSA:1.10.760.10 189 276 7.9E-71 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_21090 1689b8af18442f212429af20af1d11d3 316 PIRSF PIRSF000006 5 303 4.3E-101 T 14-10-2018 IPR004678 Cytochrome c oxidase cbb3-type, subunit III LH59_21090 1689b8af18442f212429af20af1d11d3 316 TIGRFAM TIGR00782 ccoP: cytochrome c oxidase, cbb3-type, subunit III 40 302 2.3E-80 T 14-10-2018 IPR004678 Cytochrome c oxidase cbb3-type, subunit III LH59_21090 1689b8af18442f212429af20af1d11d3 316 Gene3D G3DSA:1.10.760.10 111 299 7.9E-71 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_21090 1689b8af18442f212429af20af1d11d3 316 Gene3D G3DSA:1.20.58.1490 5 101 1.7E-27 T 14-10-2018 IPR038414 Cbb3-type cytochrome c oxidase subunit CcoP, N-terminal domain superfamily LH59_21090 1689b8af18442f212429af20af1d11d3 316 SUPERFAMILY SSF46626 222 305 3.15E-24 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_23900 b2e4c5077492936cd695f72d70b5d634 362 Pfam PF13492 GAF domain 35 166 6.9E-7 T 14-10-2018 IPR003018 GAF domain GO:0005515 LH59_23900 b2e4c5077492936cd695f72d70b5d634 362 SMART SM00065 28 174 1.2E-5 T 14-10-2018 IPR003018 GAF domain GO:0005515 LH59_23900 b2e4c5077492936cd695f72d70b5d634 362 SUPERFAMILY SSF55781 29 177 4.8E-18 T 14-10-2018 LH59_23900 b2e4c5077492936cd695f72d70b5d634 362 Gene3D G3DSA:3.30.70.270 174 361 3.5E-42 T 14-10-2018 LH59_23900 b2e4c5077492936cd695f72d70b5d634 362 Gene3D G3DSA:3.30.450.40 7 173 1.1E-16 T 14-10-2018 IPR029016 GAF-like domain superfamily LH59_23900 b2e4c5077492936cd695f72d70b5d634 362 Pfam PF00990 Diguanylate cyclase, GGDEF domain 184 356 1.4E-32 T 14-10-2018 IPR000160 GGDEF domain LH59_23900 b2e4c5077492936cd695f72d70b5d634 362 SUPERFAMILY SSF55073 189 356 2.51E-33 T 14-10-2018 IPR029787 Nucleotide cyclase LH59_23900 b2e4c5077492936cd695f72d70b5d634 362 SMART SM00267 173 362 2.4E-35 T 14-10-2018 IPR000160 GGDEF domain LH59_23900 b2e4c5077492936cd695f72d70b5d634 362 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 183 357 4.8E-35 T 14-10-2018 IPR000160 GGDEF domain LH59_26805 c20ad96ccafade40a8ca4eaf19b5ee33 299 SUPERFAMILY SSF46785 3 109 3.43E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_26805 c20ad96ccafade40a8ca4eaf19b5ee33 299 Gene3D G3DSA:3.40.190.290 89 297 8.0E-74 T 14-10-2018 LH59_26805 c20ad96ccafade40a8ca4eaf19b5ee33 299 Gene3D G3DSA:1.10.10.10 1 84 2.1E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_26805 c20ad96ccafade40a8ca4eaf19b5ee33 299 TIGRFAM TIGR03298 argP: transcriptional regulator, ArgP family 3 294 2.2E-115 T 14-10-2018 IPR017685 HTH-type transcriptional regulator ArgP LH59_26805 c20ad96ccafade40a8ca4eaf19b5ee33 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 62 2.1E-14 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_26805 c20ad96ccafade40a8ca4eaf19b5ee33 299 Pfam PF03466 LysR substrate binding domain 94 291 6.0E-12 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_26805 c20ad96ccafade40a8ca4eaf19b5ee33 299 SUPERFAMILY SSF53850 91 293 2.71E-19 T 14-10-2018 LH59_22115 8761f22e2b1dc390d2d8007c96fcc65e 323 Gene3D G3DSA:3.40.190.150 28 313 6.0E-106 T 14-10-2018 LH59_22115 8761f22e2b1dc390d2d8007c96fcc65e 323 Gene3D G3DSA:3.40.190.10 125 248 6.0E-106 T 14-10-2018 LH59_22115 8761f22e2b1dc390d2d8007c96fcc65e 323 PIRSF PIRSF017082 1 323 7.0E-87 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_22115 8761f22e2b1dc390d2d8007c96fcc65e 323 SUPERFAMILY SSF53850 105 286 2.33E-19 T 14-10-2018 LH59_22115 8761f22e2b1dc390d2d8007c96fcc65e 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 319 5.1E-87 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_19610 64f4d27084745f3f01755c0a26a0312e 234 Gene3D G3DSA:1.10.10.10 8 75 3.2E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_19610 64f4d27084745f3f01755c0a26a0312e 234 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 74 3.8E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_19610 64f4d27084745f3f01755c0a26a0312e 234 Gene3D G3DSA:1.20.120.530 78 209 1.8E-22 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_19610 64f4d27084745f3f01755c0a26a0312e 234 SUPERFAMILY SSF48008 80 216 1.94E-19 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_19610 64f4d27084745f3f01755c0a26a0312e 234 SMART SM00345 16 74 1.0E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_19610 64f4d27084745f3f01755c0a26a0312e 234 SMART SM00895 84 209 4.1E-14 T 14-10-2018 IPR011711 GntR, C-terminal LH59_19610 64f4d27084745f3f01755c0a26a0312e 234 SUPERFAMILY SSF46785 6 78 8.46E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_19610 64f4d27084745f3f01755c0a26a0312e 234 Pfam PF07729 FCD domain 84 205 2.0E-19 T 14-10-2018 IPR011711 GntR, C-terminal LH59_18000 72a50139edef6d6db4422555aedd07ce 409 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 42 60 - T 14-10-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site LH59_18000 72a50139edef6d6db4422555aedd07ce 409 SUPERFAMILY SSF50621 240 408 3.98E-53 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 LH59_18000 72a50139edef6d6db4422555aedd07ce 409 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 173 186 6.7E-20 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 LH59_18000 72a50139edef6d6db4422555aedd07ce 409 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 366 379 6.7E-20 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 LH59_18000 72a50139edef6d6db4422555aedd07ce 409 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 62 74 6.7E-20 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 LH59_18000 72a50139edef6d6db4422555aedd07ce 409 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 42 60 6.7E-20 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 LH59_18000 72a50139edef6d6db4422555aedd07ce 409 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 256 275 6.7E-20 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 LH59_18000 72a50139edef6d6db4422555aedd07ce 409 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 39 266 3.3E-53 T 14-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 LH59_18000 72a50139edef6d6db4422555aedd07ce 409 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 5 409 38.316 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LH59_18000 72a50139edef6d6db4422555aedd07ce 409 SUPERFAMILY SSF51419 16 268 6.02E-61 T 14-10-2018 IPR029066 PLP-binding barrel LH59_18000 72a50139edef6d6db4422555aedd07ce 409 Gene3D G3DSA:3.20.20.10 24 270 5.0E-140 T 14-10-2018 IPR029066 PLP-binding barrel LH59_18000 72a50139edef6d6db4422555aedd07ce 409 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 6 408 2.1E-122 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LH59_18000 72a50139edef6d6db4422555aedd07ce 409 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 204 220 - T 14-10-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site LH59_18000 72a50139edef6d6db4422555aedd07ce 409 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 20 366 2.7E-23 T 14-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 LH59_18000 72a50139edef6d6db4422555aedd07ce 409 Gene3D G3DSA:2.40.37.10 13 406 5.0E-140 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 LH59_18000 72a50139edef6d6db4422555aedd07ce 409 PRINTS PR01181 Diaminopimelate decarboxylase signature 376 398 6.1E-25 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LH59_18000 72a50139edef6d6db4422555aedd07ce 409 PRINTS PR01181 Diaminopimelate decarboxylase signature 60 77 6.1E-25 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LH59_18000 72a50139edef6d6db4422555aedd07ce 409 PRINTS PR01181 Diaminopimelate decarboxylase signature 284 302 6.1E-25 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LH59_18000 72a50139edef6d6db4422555aedd07ce 409 PRINTS PR01181 Diaminopimelate decarboxylase signature 148 157 6.1E-25 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LH59_15695 337f6a223ad4c598211cc9f97c85744f 438 ProSitePatterns PS00216 Sugar transport proteins signature 1. 310 325 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 LH59_15695 337f6a223ad4c598211cc9f97c85744f 438 SUPERFAMILY SSF103473 15 437 6.02E-77 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_15695 337f6a223ad4c598211cc9f97c85744f 438 Pfam PF07690 Major Facilitator Superfamily 34 396 1.6E-44 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_15695 337f6a223ad4c598211cc9f97c85744f 438 Gene3D G3DSA:1.20.1250.20 17 438 4.4E-81 T 14-10-2018 LH59_20405 f789a7529234886f524dc8f9bd7f8f35 252 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 1 238 7.1E-50 T 14-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 LH59_20405 f789a7529234886f524dc8f9bd7f8f35 252 PIRSF PIRSF004808 1 247 2.9E-57 T 14-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 LH59_20405 f789a7529234886f524dc8f9bd7f8f35 252 Gene3D G3DSA:3.40.1280.10 1 164 6.8E-53 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal LH59_20405 f789a7529234886f524dc8f9bd7f8f35 252 SUPERFAMILY SSF75217 2 161 2.22E-29 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases LH59_20405 f789a7529234886f524dc8f9bd7f8f35 252 Pfam PF00588 SpoU rRNA Methylase family 1 151 5.9E-34 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 LH59_20405 f789a7529234886f524dc8f9bd7f8f35 252 Gene3D G3DSA:1.10.8.590 180 241 8.2E-19 T 14-10-2018 LH59_23555 d763c470a32d2808287b2c5ba4b3e165 167 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 6 156 1.7E-18 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 LH59_23555 d763c470a32d2808287b2c5ba4b3e165 167 Pfam PF04542 Sigma-70 region 2 9 75 1.6E-12 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 LH59_23555 d763c470a32d2808287b2c5ba4b3e165 167 SUPERFAMILY SSF88659 101 158 1.4E-11 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like LH59_23555 d763c470a32d2808287b2c5ba4b3e165 167 Gene3D G3DSA:1.10.10.10 70 162 4.1E-10 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_23555 d763c470a32d2808287b2c5ba4b3e165 167 SUPERFAMILY SSF88946 6 92 9.81E-14 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 LH59_23555 d763c470a32d2808287b2c5ba4b3e165 167 Gene3D G3DSA:1.10.1740.10 3 69 2.7E-8 T 14-10-2018 LH59_23555 d763c470a32d2808287b2c5ba4b3e165 167 Pfam PF08281 Sigma-70, region 4 107 158 1.3E-13 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LH59_09195 65fa11c197497b9def23867d62375d70 78 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 6 65 3.9E-29 T 14-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 LH59_09195 65fa11c197497b9def23867d62375d70 78 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 1 65 28.324 T 14-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 LH59_09195 65fa11c197497b9def23867d62375d70 78 Pfam PF17209 Hfq protein 8 69 1.9E-31 T 14-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 LH59_09195 65fa11c197497b9def23867d62375d70 78 SUPERFAMILY SSF50182 8 70 3.47E-24 T 14-10-2018 IPR010920 LSM domain superfamily LH59_09195 65fa11c197497b9def23867d62375d70 78 Gene3D G3DSA:2.30.30.100 1 75 1.6E-33 T 14-10-2018 LH59_06890 6aa9aa497ca01a2a2753a9a02eb9723f 138 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 21 130 1.5E-26 T 14-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 LH59_06890 6aa9aa497ca01a2a2753a9a02eb9723f 138 PIRSF PIRSF000178 20 135 6.4E-24 T 14-10-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 LH59_06890 6aa9aa497ca01a2a2753a9a02eb9723f 138 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 23 131 8.5E-33 T 14-10-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 LH59_06890 6aa9aa497ca01a2a2753a9a02eb9723f 138 SUPERFAMILY SSF81343 7 134 3.92E-26 T 14-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 LH59_06890 6aa9aa497ca01a2a2753a9a02eb9723f 138 Gene3D G3DSA:1.20.1300.10 3 135 6.3E-32 T 14-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 LH59_03305 89f37bd54932b46041a35c02d2634ac3 278 SUPERFAMILY SSF161098 81 261 8.24E-26 T 14-10-2018 IPR035906 MetI-like superfamily LH59_03305 89f37bd54932b46041a35c02d2634ac3 278 Gene3D G3DSA:1.10.3720.10 81 276 1.5E-22 T 14-10-2018 IPR035906 MetI-like superfamily LH59_03305 89f37bd54932b46041a35c02d2634ac3 278 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 276 3.5E-22 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_25015 f0463c97f96e0f667bdf5eee23d01196 478 PIRSF PIRSF006446 1 461 4.2E-216 T 14-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 LH59_25015 f0463c97f96e0f667bdf5eee23d01196 478 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 8 436 3.4E-166 T 14-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 LH59_20365 b18026d8eb00c2f8762deb45ba0f73dd 638 TIGRFAM TIGR04244 nitrous_NosZ_RR: nitrous-oxide reductase, TAT-dependent 11 632 0.0 T 14-10-2018 IPR023644 Nitrous-oxide reductase GO:0005507|GO:0005509|GO:0050304|GO:0055114 KEGG: 00910+1.7.2.4|MetaCyc: PWY-6748|MetaCyc: PWY-7084 LH59_20365 b18026d8eb00c2f8762deb45ba0f73dd 638 Gene3D G3DSA:2.60.40.420 515 633 2.0E-35 T 14-10-2018 IPR008972 Cupredoxin LH59_20365 b18026d8eb00c2f8762deb45ba0f73dd 638 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 11 37 1.1E-4 T 14-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal LH59_20365 b18026d8eb00c2f8762deb45ba0f73dd 638 Gene3D G3DSA:2.130.10.10 51 514 1.3E-201 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 LH59_20365 b18026d8eb00c2f8762deb45ba0f73dd 638 Hamap MF_00716 Nitrous-oxide reductase [nosZ]. 2 634 57.143 T 14-10-2018 IPR023644 Nitrous-oxide reductase GO:0005507|GO:0005509|GO:0050304|GO:0055114 KEGG: 00910+1.7.2.4|MetaCyc: PWY-6748|MetaCyc: PWY-7084 LH59_20365 b18026d8eb00c2f8762deb45ba0f73dd 638 Pfam PF07732 Multicopper oxidase 541 635 2.5E-4 T 14-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 LH59_20365 b18026d8eb00c2f8762deb45ba0f73dd 638 SUPERFAMILY SSF50974 52 504 1.07E-142 T 14-10-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 LH59_20365 b18026d8eb00c2f8762deb45ba0f73dd 638 SUPERFAMILY SSF49503 506 634 6.26E-37 T 14-10-2018 IPR008972 Cupredoxin LH59_27205 8b0eb70147f83e63f5178a421cc77ec0 187 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 26 177 7.0E-47 T 14-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 LH59_27205 8b0eb70147f83e63f5178a421cc77ec0 187 SUPERFAMILY SSF89028 8 178 2.55E-59 T 14-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 LH59_27205 8b0eb70147f83e63f5178a421cc77ec0 187 Pfam PF01923 Cobalamin adenosyltransferase 8 165 1.5E-57 T 14-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 LH59_27205 8b0eb70147f83e63f5178a421cc77ec0 187 Gene3D G3DSA:1.20.1200.10 17 182 3.2E-63 T 14-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 LH59_27205 8b0eb70147f83e63f5178a421cc77ec0 187 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 10 178 5.7E-62 T 14-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 LH59_21935 89adc55b1dcf3132711c35b51a9a14d3 200 SUPERFAMILY SSF75471 5 91 1.83E-23 T 14-10-2018 IPR035920 YhbY-like superfamily LH59_21935 89adc55b1dcf3132711c35b51a9a14d3 200 Pfam PF01985 CRS1 / YhbY (CRM) domain 6 89 3.3E-16 T 14-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 LH59_21935 89adc55b1dcf3132711c35b51a9a14d3 200 Gene3D G3DSA:3.30.110.60 4 101 1.9E-27 T 14-10-2018 IPR035920 YhbY-like superfamily LH59_21935 89adc55b1dcf3132711c35b51a9a14d3 200 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 14 90 9.0E-36 T 14-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 LH59_21935 89adc55b1dcf3132711c35b51a9a14d3 200 SMART SM01103 6 89 2.1E-35 T 14-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 LH59_10925 c3fb2778e1a7ab2e8762f948a090af9e 234 Gene3D G3DSA:2.40.30.20 1 88 5.9E-26 T 14-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 LH59_10925 c3fb2778e1a7ab2e8762f948a090af9e 234 Pfam PF00677 Lumazine binding domain 101 186 5.6E-21 T 14-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 LH59_10925 c3fb2778e1a7ab2e8762f948a090af9e 234 Pfam PF00677 Lumazine binding domain 3 88 4.4E-17 T 14-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 LH59_10925 c3fb2778e1a7ab2e8762f948a090af9e 234 Gene3D G3DSA:2.40.30.20 103 206 2.1E-26 T 14-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 LH59_10925 c3fb2778e1a7ab2e8762f948a090af9e 234 SUPERFAMILY SSF63380 1 89 1.7E-21 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel LH59_10925 c3fb2778e1a7ab2e8762f948a090af9e 234 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 201 3.9E-56 T 14-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 LH59_10925 c3fb2778e1a7ab2e8762f948a090af9e 234 SUPERFAMILY SSF63380 94 201 1.53E-26 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel LH59_10925 c3fb2778e1a7ab2e8762f948a090af9e 234 PIRSF PIRSF000498 1 213 4.7E-57 T 14-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 LH59_15925 1b436b97cbdbacc86488154d2fe093f2 506 Pfam PF00206 Lyase 59 304 9.0E-42 T 14-10-2018 IPR022761 Fumarate lyase, N-terminal LH59_15925 1b436b97cbdbacc86488154d2fe093f2 506 Pfam PF14698 Argininosuccinate lyase C-terminal 368 445 5.9E-18 T 14-10-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 LH59_15925 1b436b97cbdbacc86488154d2fe093f2 506 PRINTS PR00145 Argininosuccinate lyase family signature 235 259 9.9E-38 T 14-10-2018 LH59_15925 1b436b97cbdbacc86488154d2fe093f2 506 PRINTS PR00145 Argininosuccinate lyase family signature 105 127 9.9E-38 T 14-10-2018 LH59_15925 1b436b97cbdbacc86488154d2fe093f2 506 PRINTS PR00145 Argininosuccinate lyase family signature 197 213 9.9E-38 T 14-10-2018 LH59_15925 1b436b97cbdbacc86488154d2fe093f2 506 PRINTS PR00145 Argininosuccinate lyase family signature 146 166 9.9E-38 T 14-10-2018 LH59_15925 1b436b97cbdbacc86488154d2fe093f2 506 PRINTS PR00145 Argininosuccinate lyase family signature 279 295 9.9E-38 T 14-10-2018 LH59_15925 1b436b97cbdbacc86488154d2fe093f2 506 Gene3D G3DSA:1.10.40.30 365 446 2.5E-141 T 14-10-2018 LH59_15925 1b436b97cbdbacc86488154d2fe093f2 506 Hamap MF_00006 Argininosuccinate lyase [argH]. 3 467 31.216 T 14-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 LH59_15925 1b436b97cbdbacc86488154d2fe093f2 506 Gene3D G3DSA:1.20.200.10 123 463 2.5E-141 T 14-10-2018 LH59_15925 1b436b97cbdbacc86488154d2fe093f2 506 PRINTS PR00149 Fumarate lyase superfamily signature 106 124 3.7E-21 T 14-10-2018 IPR000362 Fumarate lyase family LH59_15925 1b436b97cbdbacc86488154d2fe093f2 506 PRINTS PR00149 Fumarate lyase superfamily signature 235 262 3.7E-21 T 14-10-2018 IPR000362 Fumarate lyase family LH59_15925 1b436b97cbdbacc86488154d2fe093f2 506 PRINTS PR00149 Fumarate lyase superfamily signature 279 295 3.7E-21 T 14-10-2018 IPR000362 Fumarate lyase family LH59_15925 1b436b97cbdbacc86488154d2fe093f2 506 PRINTS PR00149 Fumarate lyase superfamily signature 151 169 3.7E-21 T 14-10-2018 IPR000362 Fumarate lyase family LH59_15925 1b436b97cbdbacc86488154d2fe093f2 506 SUPERFAMILY SSF48557 33 469 1.37E-103 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 LH59_15925 1b436b97cbdbacc86488154d2fe093f2 506 TIGRFAM TIGR00838 argH: argininosuccinate lyase 39 467 1.0E-113 T 14-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 LH59_15925 1b436b97cbdbacc86488154d2fe093f2 506 Gene3D G3DSA:1.10.275.10 39 233 2.5E-141 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal LH59_08100 02cb1be2b6dee57ab76884e871e5ab06 454 Gene3D G3DSA:3.40.50.1010 1 147 8.0E-23 T 14-10-2018 LH59_08100 02cb1be2b6dee57ab76884e871e5ab06 454 Gene3D G3DSA:3.40.50.300 238 451 2.2E-64 T 14-10-2018 LH59_08100 02cb1be2b6dee57ab76884e871e5ab06 454 Pfam PF13638 PIN domain 1 144 2.5E-39 T 14-10-2018 IPR002716 PIN domain LH59_08100 02cb1be2b6dee57ab76884e871e5ab06 454 SMART SM00670 1 132 7.6E-10 T 14-10-2018 IPR002716 PIN domain LH59_08100 02cb1be2b6dee57ab76884e871e5ab06 454 SUPERFAMILY SSF88723 1 146 1.39E-10 T 14-10-2018 IPR029060 PIN-like domain superfamily LH59_08100 02cb1be2b6dee57ab76884e871e5ab06 454 Pfam PF02562 PhoH-like protein 240 442 7.0E-53 T 14-10-2018 IPR003714 PhoH-like protein GO:0005524 LH59_08100 02cb1be2b6dee57ab76884e871e5ab06 454 SUPERFAMILY SSF52540 121 432 9.96E-29 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_19360 beed30f4c127f22312343ec640fc485a 361 Gene3D G3DSA:1.20.58.1130 46 248 3.3E-12 T 14-10-2018 LH59_19360 beed30f4c127f22312343ec640fc485a 361 Pfam PF01699 Sodium/calcium exchanger protein 41 185 5.7E-14 T 14-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 LH59_19360 beed30f4c127f22312343ec640fc485a 361 Pfam PF01699 Sodium/calcium exchanger protein 217 356 6.0E-6 T 14-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 LH59_19360 beed30f4c127f22312343ec640fc485a 361 Gene3D G3DSA:1.20.1420.30 67 350 3.3E-12 T 14-10-2018 LH59_14980 97df7ecf83df9d1de822670ca45f2db4 485 Pfam PF00324 Amino acid permease 1 450 4.5E-129 T 14-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 LH59_14980 97df7ecf83df9d1de822670ca45f2db4 485 Gene3D G3DSA:1.20.1740.10 1 459 3.9E-58 T 14-10-2018 LH59_14980 97df7ecf83df9d1de822670ca45f2db4 485 PIRSF PIRSF006060 1 469 5.4E-73 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 LH59_27940 19ad20b0acd4d8611f827eeb50283c47 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 230 5.0E-10 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_27940 19ad20b0acd4d8611f827eeb50283c47 233 SMART SM00862 152 230 1.0E-9 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_27940 19ad20b0acd4d8611f827eeb50283c47 233 SUPERFAMILY SSF46894 143 231 8.5E-12 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LH59_27940 19ad20b0acd4d8611f827eeb50283c47 233 SUPERFAMILY SSF52172 1 121 1.42E-14 T 14-10-2018 IPR011006 CheY-like superfamily LH59_27940 19ad20b0acd4d8611f827eeb50283c47 233 Pfam PF00072 Response regulator receiver domain 12 111 6.1E-6 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_27940 19ad20b0acd4d8611f827eeb50283c47 233 Gene3D G3DSA:3.40.50.2300 1 121 2.0E-9 T 14-10-2018 LH59_27940 19ad20b0acd4d8611f827eeb50283c47 233 Gene3D G3DSA:1.10.10.10 136 233 4.9E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_15010 2a7828c05acfd0d29ec99a412fce4a9e 342 SUPERFAMILY SSF46955 3 108 4.03E-28 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily LH59_15010 2a7828c05acfd0d29ec99a412fce4a9e 342 Pfam PF13411 MerR HTH family regulatory protein 4 71 1.1E-16 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LH59_15010 2a7828c05acfd0d29ec99a412fce4a9e 342 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 4.4E-9 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LH59_15010 2a7828c05acfd0d29ec99a412fce4a9e 342 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 4.4E-9 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LH59_15010 2a7828c05acfd0d29ec99a412fce4a9e 342 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 4.4E-9 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LH59_15010 2a7828c05acfd0d29ec99a412fce4a9e 342 Pfam PF07739 TipAS antibiotic-recognition domain 250 335 2.7E-5 T 14-10-2018 IPR012925 TipAS antibiotic-recognition domain LH59_15010 2a7828c05acfd0d29ec99a412fce4a9e 342 Pfam PF07739 TipAS antibiotic-recognition domain 154 228 6.3E-6 T 14-10-2018 IPR012925 TipAS antibiotic-recognition domain LH59_15010 2a7828c05acfd0d29ec99a412fce4a9e 342 SMART SM00422 3 72 7.3E-29 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LH59_01790 f40cd3e310c6b4b7a68fd0998bec51fc 214 Gene3D G3DSA:3.40.30.10 10 205 1.5E-57 T 14-10-2018 LH59_01790 f40cd3e310c6b4b7a68fd0998bec51fc 214 Pfam PF01323 DSBA-like thioredoxin domain 11 196 4.1E-40 T 14-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 LH59_01790 f40cd3e310c6b4b7a68fd0998bec51fc 214 PIRSF PIRSF006386 5 211 1.4E-58 T 14-10-2018 IPR014440 HCCA isomerase/glutathione S-transferase kappa Reactome: R-HSA-156590|Reactome: R-HSA-9033241 LH59_01790 f40cd3e310c6b4b7a68fd0998bec51fc 214 SUPERFAMILY SSF52833 9 200 6.31E-41 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_27800 9931a5c3e661e33993935493d5de31be 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 26.295 T 14-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 LH59_27800 9931a5c3e661e33993935493d5de31be 122 SUPERFAMILY SSF50193 1 122 9.55E-51 T 14-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 LH59_27800 9931a5c3e661e33993935493d5de31be 122 SMART SM01374 1 122 4.8E-83 T 14-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 LH59_27800 9931a5c3e661e33993935493d5de31be 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 8.3E-54 T 14-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 LH59_27800 9931a5c3e661e33993935493d5de31be 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 9.3E-57 T 14-10-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 LH59_27800 9931a5c3e661e33993935493d5de31be 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 14-10-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27800 9931a5c3e661e33993935493d5de31be 122 Gene3D G3DSA:2.40.150.20 1 122 7.9E-53 T 14-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 LH59_17005 7d0c2d65635ae9543a048054bd9d8d48 701 SUPERFAMILY SSF56300 43 414 6.25E-72 T 14-10-2018 LH59_17005 7d0c2d65635ae9543a048054bd9d8d48 701 Pfam PF00149 Calcineurin-like phosphoesterase 49 313 1.3E-6 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 LH59_17005 7d0c2d65635ae9543a048054bd9d8d48 701 Pfam PF02872 5'-nucleotidase, C-terminal domain 481 607 2.2E-20 T 14-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 LH59_17005 7d0c2d65635ae9543a048054bd9d8d48 701 PRINTS PR01607 Apyrase family signature 267 284 4.8E-27 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 LH59_17005 7d0c2d65635ae9543a048054bd9d8d48 701 PRINTS PR01607 Apyrase family signature 489 512 4.8E-27 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 LH59_17005 7d0c2d65635ae9543a048054bd9d8d48 701 PRINTS PR01607 Apyrase family signature 296 319 4.8E-27 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 LH59_17005 7d0c2d65635ae9543a048054bd9d8d48 701 PRINTS PR01607 Apyrase family signature 45 63 4.8E-27 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 LH59_17005 7d0c2d65635ae9543a048054bd9d8d48 701 PRINTS PR01607 Apyrase family signature 582 601 4.8E-27 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 LH59_17005 7d0c2d65635ae9543a048054bd9d8d48 701 PRINTS PR01607 Apyrase family signature 340 360 4.8E-27 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 LH59_17005 7d0c2d65635ae9543a048054bd9d8d48 701 Gene3D G3DSA:3.60.21.10 41 416 2.2E-100 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like LH59_17005 7d0c2d65635ae9543a048054bd9d8d48 701 SUPERFAMILY SSF55816 415 641 6.67E-33 T 14-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 LH59_17005 7d0c2d65635ae9543a048054bd9d8d48 701 ProSitePatterns PS00786 5'-nucleotidase signature 2. 133 144 - T 14-10-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 LH59_17005 7d0c2d65635ae9543a048054bd9d8d48 701 Gene3D G3DSA:3.90.780.10 465 641 1.0E-48 T 14-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 LH59_17005 7d0c2d65635ae9543a048054bd9d8d48 701 ProSitePatterns PS00785 5'-nucleotidase signature 1. 47 59 - T 14-10-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 LH59_05650 45f6d28a6348743191bfcbfdb8eb9b04 338 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 14 177 3.3E-74 T 14-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 LH59_05650 45f6d28a6348743191bfcbfdb8eb9b04 338 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 183 326 3.9E-63 T 14-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 LH59_05650 45f6d28a6348743191bfcbfdb8eb9b04 338 Gene3D G3DSA:3.40.50.720 1 181 8.4E-78 T 14-10-2018 LH59_05650 45f6d28a6348743191bfcbfdb8eb9b04 338 SUPERFAMILY SSF48179 183 332 3.06E-68 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 LH59_05650 45f6d28a6348743191bfcbfdb8eb9b04 338 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 1 328 44.359 T 14-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 LH59_05650 45f6d28a6348743191bfcbfdb8eb9b04 338 SUPERFAMILY SSF51735 1 182 1.56E-74 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_05650 45f6d28a6348743191bfcbfdb8eb9b04 338 PIRSF PIRSF000116 201 331 7.3E-12 T 14-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 LH59_05650 45f6d28a6348743191bfcbfdb8eb9b04 338 PIRSF PIRSF000116 2 205 5.1E-46 T 14-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 LH59_05650 45f6d28a6348743191bfcbfdb8eb9b04 338 Gene3D G3DSA:1.10.3730.40 182 338 2.3E-72 T 14-10-2018 LH59_05650 45f6d28a6348743191bfcbfdb8eb9b04 338 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 14 326 3.4E-134 T 14-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 LH59_02955 5df8613a5b74cd634ac7a26323ae5b30 546 ProSitePatterns PS00455 Putative AMP-binding domain signature. 208 219 - T 14-10-2018 IPR020845 AMP-binding, conserved site LH59_02955 5df8613a5b74cd634ac7a26323ae5b30 546 Pfam PF00501 AMP-binding enzyme 50 449 2.0E-75 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 LH59_02955 5df8613a5b74cd634ac7a26323ae5b30 546 Pfam PF13193 AMP-binding enzyme C-terminal domain 458 536 4.8E-24 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain LH59_02955 5df8613a5b74cd634ac7a26323ae5b30 546 Gene3D G3DSA:3.40.50.12780 33 442 4.7E-95 T 14-10-2018 LH59_02955 5df8613a5b74cd634ac7a26323ae5b30 546 SUPERFAMILY SSF56801 29 545 2.75E-135 T 14-10-2018 LH59_02955 5df8613a5b74cd634ac7a26323ae5b30 546 Gene3D G3DSA:3.30.300.30 443 546 4.8E-29 T 14-10-2018 LH59_15255 f90598b0bd453793565c175bb87bfa8f 117 Pfam PF03795 YCII-related domain 1 112 3.8E-19 T 14-10-2018 IPR005545 YCII-related LH59_15255 f90598b0bd453793565c175bb87bfa8f 117 Gene3D G3DSA:3.30.70.1060 1 114 6.5E-35 T 14-10-2018 LH59_15255 f90598b0bd453793565c175bb87bfa8f 117 SUPERFAMILY SSF54909 1 114 1.56E-32 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel LH59_07615 6460294215321bace9ecd8288f3a59eb 411 SUPERFAMILY SSF46785 87 162 5.74E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_07615 6460294215321bace9ecd8288f3a59eb 411 SUPERFAMILY SSF46785 2 84 8.43E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_07615 6460294215321bace9ecd8288f3a59eb 411 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 16 174 3.5E-30 T 14-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 LH59_07615 6460294215321bace9ecd8288f3a59eb 411 Gene3D G3DSA:1.10.10.10 3 84 2.7E-8 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_07615 6460294215321bace9ecd8288f3a59eb 411 Gene3D G3DSA:1.10.10.10 85 180 4.1E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_07615 6460294215321bace9ecd8288f3a59eb 411 Pfam PF04079 Segregation and condensation complex subunit ScpB 12 170 3.7E-45 T 14-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 LH59_10160 983ac98dc5506f37052253ff95664844 275 Pfam PF03781 Sulfatase-modifying factor enzyme 1 27 270 1.2E-39 T 14-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 LH59_10160 983ac98dc5506f37052253ff95664844 275 SUPERFAMILY SSF56436 34 271 2.83E-38 T 14-10-2018 IPR016187 C-type lectin fold LH59_10160 983ac98dc5506f37052253ff95664844 275 Gene3D G3DSA:3.90.1580.10 38 273 5.6E-29 T 14-10-2018 LH59_08345 8eacb17c4f625d3ccb5bf3c8094990ed 221 Pfam PF11041 Protein of unknown function (DUF2612) 9 187 4.4E-56 T 14-10-2018 IPR021283 Protein of unknown function DUF2612 LH59_17975 0a53f973351982bacb1e462c5020b949 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.3E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_17975 0a53f973351982bacb1e462c5020b949 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.3E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_17975 0a53f973351982bacb1e462c5020b949 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.3E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_17975 0a53f973351982bacb1e462c5020b949 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.3E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_17975 0a53f973351982bacb1e462c5020b949 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 1.3E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_17975 0a53f973351982bacb1e462c5020b949 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 1.3E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_17975 0a53f973351982bacb1e462c5020b949 252 Pfam PF00106 short chain dehydrogenase 6 195 1.6E-44 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_17975 0a53f973351982bacb1e462c5020b949 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 7.2E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_17975 0a53f973351982bacb1e462c5020b949 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 7.2E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_17975 0a53f973351982bacb1e462c5020b949 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 7.2E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_17975 0a53f973351982bacb1e462c5020b949 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LH59_17975 0a53f973351982bacb1e462c5020b949 252 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 189 0.0081 T 14-10-2018 LH59_17975 0a53f973351982bacb1e462c5020b949 252 SUPERFAMILY SSF51735 3 247 8.17E-59 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_17975 0a53f973351982bacb1e462c5020b949 252 Gene3D G3DSA:3.40.50.720 1 251 1.4E-74 T 14-10-2018 LH59_15545 e9f22af05984d75a1417805ae85fcfff 327 Gene3D G3DSA:3.40.1730.10 10 185 2.0E-18 T 14-10-2018 IPR038225 T6S-associated protein TagF superfamily LH59_15545 e9f22af05984d75a1417805ae85fcfff 327 TIGRFAM TIGR03373 VI_minor_4: type VI secretion-associated protein, BMA_A0400 family 12 145 3.9E-35 T 14-10-2018 IPR017748 T6S-associated protein TagF LH59_15545 e9f22af05984d75a1417805ae85fcfff 327 Pfam PF09867 Uncharacterized protein conserved in bacteria (DUF2094) 13 140 2.6E-25 T 14-10-2018 IPR017748 T6S-associated protein TagF LH59_21585 ae8878b131b6dceb98f902bd51a0d1e0 237 Pfam PF13419 Haloacid dehalogenase-like hydrolase 103 203 9.5E-13 T 14-10-2018 LH59_21585 ae8878b131b6dceb98f902bd51a0d1e0 237 Gene3D G3DSA:3.40.50.1000 11 224 6.5E-53 T 14-10-2018 IPR023214 HAD superfamily LH59_21585 ae8878b131b6dceb98f902bd51a0d1e0 237 Gene3D G3DSA:1.10.150.750 23 102 6.5E-53 T 14-10-2018 LH59_21585 ae8878b131b6dceb98f902bd51a0d1e0 237 TIGRFAM TIGR01428 HAD_type_II: haloacid dehalogenase, type II 11 207 9.2E-41 T 14-10-2018 IPR006328 L-2-Haloacid dehalogenase GO:0019120 KEGG: 00361+3.8.1.2|KEGG: 00625+3.8.1.2|MetaCyc: PWY-7425 LH59_21585 ae8878b131b6dceb98f902bd51a0d1e0 237 SUPERFAMILY SSF56784 9 232 1.8E-43 T 14-10-2018 IPR036412 HAD-like superfamily LH59_21585 ae8878b131b6dceb98f902bd51a0d1e0 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 192 205 1.0E-9 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 LH59_21585 ae8878b131b6dceb98f902bd51a0d1e0 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 9 20 1.0E-9 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 LH59_21585 ae8878b131b6dceb98f902bd51a0d1e0 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 117 130 1.0E-9 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 LH59_21585 ae8878b131b6dceb98f902bd51a0d1e0 237 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 115 183 4.6E-6 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 LH59_21585 ae8878b131b6dceb98f902bd51a0d1e0 237 TIGRFAM TIGR01493 HAD-SF-IA-v2: HAD hydrolase, family IA, variant 2 12 193 5.6E-12 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 LH59_19120 b17416fa60f91ac2bacb7ae7a21c0274 321 SUPERFAMILY SSF53213 2 314 2.09E-63 T 14-10-2018 LH59_19120 b17416fa60f91ac2bacb7ae7a21c0274 321 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 3 306 2.1E-38 T 14-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 LH59_03250 04647a3a06c5e656486589b5846ae70b 976 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 295 366 6.8E-21 T 14-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 LH59_03250 04647a3a06c5e656486589b5846ae70b 976 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 755 777 - T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 LH59_03250 04647a3a06c5e656486589b5846ae70b 976 PRINTS PR01183 Ribonucleotide reductase large chain signature 690 713 8.4E-43 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 LH59_03250 04647a3a06c5e656486589b5846ae70b 976 PRINTS PR01183 Ribonucleotide reductase large chain signature 766 793 8.4E-43 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 LH59_03250 04647a3a06c5e656486589b5846ae70b 976 PRINTS PR01183 Ribonucleotide reductase large chain signature 447 466 8.4E-43 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 LH59_03250 04647a3a06c5e656486589b5846ae70b 976 PRINTS PR01183 Ribonucleotide reductase large chain signature 662 684 8.4E-43 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 LH59_03250 04647a3a06c5e656486589b5846ae70b 976 PRINTS PR01183 Ribonucleotide reductase large chain signature 582 593 8.4E-43 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 LH59_03250 04647a3a06c5e656486589b5846ae70b 976 PRINTS PR01183 Ribonucleotide reductase large chain signature 624 647 8.4E-43 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 LH59_03250 04647a3a06c5e656486589b5846ae70b 976 SUPERFAMILY SSF48168 160 370 1.57E-58 T 14-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 LH59_03250 04647a3a06c5e656486589b5846ae70b 976 SUPERFAMILY SSF51998 371 914 2.96E-180 T 14-10-2018 LH59_03250 04647a3a06c5e656486589b5846ae70b 976 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 298 914 2.5E-210 T 14-10-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 LH59_03250 04647a3a06c5e656486589b5846ae70b 976 Gene3D G3DSA:3.20.70.20 273 915 3.7E-245 T 14-10-2018 LH59_03250 04647a3a06c5e656486589b5846ae70b 976 Pfam PF02867 Ribonucleotide reductase, barrel domain 372 911 8.0E-182 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 LH59_03250 04647a3a06c5e656486589b5846ae70b 976 Pfam PF03477 ATP cone domain 34 130 1.2E-16 T 14-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 LH59_18425 13c430a41490844a3bde4faf4b251600 145 Pfam PF13673 Acetyltransferase (GNAT) domain 37 131 6.0E-16 T 14-10-2018 IPR000182 GNAT domain LH59_18425 13c430a41490844a3bde4faf4b251600 145 Gene3D G3DSA:3.40.630.30 1 145 5.0E-36 T 14-10-2018 LH59_18425 13c430a41490844a3bde4faf4b251600 145 SUPERFAMILY SSF55729 1 143 6.73E-26 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_03780 ddb047e1921b094210e4cdc993cc514f 266 Pfam PF00005 ABC transporter 31 170 7.5E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_03780 ddb047e1921b094210e4cdc993cc514f 266 SMART SM00382 34 222 2.3E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_03780 ddb047e1921b094210e4cdc993cc514f 266 Gene3D G3DSA:3.40.50.300 1 257 5.9E-61 T 14-10-2018 LH59_03780 ddb047e1921b094210e4cdc993cc514f 266 SUPERFAMILY SSF52540 7 233 1.28E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_03780 ddb047e1921b094210e4cdc993cc514f 266 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_08660 e3033c92c9d3ee14d800f5397b9f84a7 244 Pfam PF10707 PhoP regulatory network protein YrbL 23 223 6.4E-69 T 14-10-2018 IPR019647 PhoP regulatory network protein YrbL LH59_20065 fc7fbb0f6db67d78b9652eba81697931 796 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 194 293 1.9E-9 T 14-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 LH59_20065 fc7fbb0f6db67d78b9652eba81697931 796 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 8 190 2.7E-44 T 14-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 LH59_20065 fc7fbb0f6db67d78b9652eba81697931 796 SUPERFAMILY SSF52096 486 792 1.31E-30 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily LH59_20065 fc7fbb0f6db67d78b9652eba81697931 796 SUPERFAMILY SSF48179 344 458 1.28E-15 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 LH59_20065 fc7fbb0f6db67d78b9652eba81697931 796 Pfam PF00378 Enoyl-CoA hydratase/isomerase 499 625 4.1E-12 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 LH59_20065 fc7fbb0f6db67d78b9652eba81697931 796 SUPERFAMILY SSF51735 5 192 3.72E-43 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_20065 fc7fbb0f6db67d78b9652eba81697931 796 Gene3D G3DSA:3.40.50.720 1 194 1.3E-56 T 14-10-2018 LH59_20065 fc7fbb0f6db67d78b9652eba81697931 796 SUPERFAMILY SSF48179 192 311 1.28E-20 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 LH59_20065 fc7fbb0f6db67d78b9652eba81697931 796 Gene3D G3DSA:3.90.226.10 480 682 1.4E-25 T 14-10-2018 LH59_20065 fc7fbb0f6db67d78b9652eba81697931 796 Gene3D G3DSA:1.10.1040.10 195 313 2.7E-16 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 LH59_00070 33150475b84892939357a4a87ca273b2 229 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 17 120 2.0E-22 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 LH59_00070 33150475b84892939357a4a87ca273b2 229 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 226 9.3E-20 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_00070 33150475b84892939357a4a87ca273b2 229 SUPERFAMILY SSF161098 17 211 1.31E-38 T 14-10-2018 IPR035906 MetI-like superfamily LH59_00070 33150475b84892939357a4a87ca273b2 229 Gene3D G3DSA:1.10.3720.10 3 227 1.6E-50 T 14-10-2018 IPR035906 MetI-like superfamily LH59_24540 5e68a7adde2d430106f9ffb21aeb907b 316 SMART SM01400 6 123 1.1E-72 T 14-10-2018 LH59_24540 5e68a7adde2d430106f9ffb21aeb907b 316 Gene3D G3DSA:3.40.50.2020 9 303 4.1E-127 T 14-10-2018 LH59_24540 5e68a7adde2d430106f9ffb21aeb907b 316 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 7 123 1.0E-46 T 14-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 LH59_24540 5e68a7adde2d430106f9ffb21aeb907b 316 Pfam PF14572 Phosphoribosyl synthetase-associated domain 205 314 2.4E-28 T 14-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 LH59_24540 5e68a7adde2d430106f9ffb21aeb907b 316 SUPERFAMILY SSF53271 71 306 6.51E-65 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like LH59_24540 5e68a7adde2d430106f9ffb21aeb907b 316 Hamap MF_00583_B Putative ribose-phosphate pyrophosphokinase [prs]. 6 315 48.387 T 14-10-2018 IPR037515 Ribose-phosphate pyrophosphokinase, bacterial-type GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 LH59_24540 5e68a7adde2d430106f9ffb21aeb907b 316 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 131 146 - T 14-10-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 LH59_24540 5e68a7adde2d430106f9ffb21aeb907b 316 Gene3D G3DSA:3.40.50.2020 150 291 4.1E-127 T 14-10-2018 LH59_24540 5e68a7adde2d430106f9ffb21aeb907b 316 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 7 314 3.2E-119 T 14-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 LH59_07520 791260ec72c7bd2b26532be42202429a 438 Gene3D G3DSA:3.40.50.12780 2 329 3.1E-143 T 14-10-2018 LH59_07520 791260ec72c7bd2b26532be42202429a 438 PIRSF PIRSF006444 3 437 2.7E-207 T 14-10-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 LH59_07520 791260ec72c7bd2b26532be42202429a 438 Pfam PF14535 AMP-binding enzyme C-terminal domain 338 435 8.5E-24 T 14-10-2018 IPR028154 AMP-dependent ligase, C-terminal LH59_07520 791260ec72c7bd2b26532be42202429a 438 TIGRFAM TIGR02155 PA_CoA_ligase: phenylacetate-CoA ligase 14 435 1.3E-219 T 14-10-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 LH59_07520 791260ec72c7bd2b26532be42202429a 438 Pfam PF00501 AMP-binding enzyme 92 292 3.8E-18 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 LH59_07520 791260ec72c7bd2b26532be42202429a 438 Gene3D G3DSA:3.30.300.30 330 436 1.2E-28 T 14-10-2018 LH59_07520 791260ec72c7bd2b26532be42202429a 438 SUPERFAMILY SSF56801 20 432 1.96E-64 T 14-10-2018 LH59_25265 a045a406ea5408b63f4c4e4959a71a8e 386 SUPERFAMILY SSF46955 4 54 1.46E-5 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily LH59_25265 a045a406ea5408b63f4c4e4959a71a8e 386 Gene3D G3DSA:1.10.580.10 200 370 7.6E-41 T 14-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 LH59_25265 a045a406ea5408b63f4c4e4959a71a8e 386 Pfam PF00285 Citrate synthase, C-terminal domain 71 380 7.9E-47 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 LH59_25265 a045a406ea5408b63f4c4e4959a71a8e 386 Pfam PF12728 Helix-turn-helix domain 7 54 8.5E-7 T 14-10-2018 LH59_25265 a045a406ea5408b63f4c4e4959a71a8e 386 PRINTS PR00143 Citrate synthase signature 203 218 8.4E-15 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 LH59_25265 a045a406ea5408b63f4c4e4959a71a8e 386 PRINTS PR00143 Citrate synthase signature 277 297 8.4E-15 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 LH59_25265 a045a406ea5408b63f4c4e4959a71a8e 386 PRINTS PR00143 Citrate synthase signature 225 253 8.4E-15 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 LH59_25265 a045a406ea5408b63f4c4e4959a71a8e 386 PRINTS PR00143 Citrate synthase signature 350 364 8.4E-15 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 LH59_25265 a045a406ea5408b63f4c4e4959a71a8e 386 SUPERFAMILY SSF48256 71 384 4.06E-54 T 14-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 LH59_25265 a045a406ea5408b63f4c4e4959a71a8e 386 Gene3D G3DSA:1.10.230.10 251 344 7.6E-41 T 14-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain LH59_23170 7b55999410417bf814b560f5afceed1f 262 SUPERFAMILY SSF52540 2 236 5.78E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_23170 7b55999410417bf814b560f5afceed1f 262 SMART SM00382 27 220 1.5E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_23170 7b55999410417bf814b560f5afceed1f 262 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_23170 7b55999410417bf814b560f5afceed1f 262 Pfam PF00005 ABC transporter 18 172 2.6E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_23170 7b55999410417bf814b560f5afceed1f 262 Gene3D G3DSA:3.40.50.300 1 260 6.9E-68 T 14-10-2018 LH59_22620 3c98628b97a29285da822c1bf6f97871 750 Gene3D G3DSA:3.40.50.10950 446 746 1.4E-83 T 14-10-2018 LH59_22620 3c98628b97a29285da822c1bf6f97871 750 Gene3D G3DSA:3.40.50.10750 577 719 1.4E-83 T 14-10-2018 LH59_22620 3c98628b97a29285da822c1bf6f97871 750 Pfam PF03949 Malic enzyme, NAD binding domain 165 360 4.3E-20 T 14-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 LH59_22620 3c98628b97a29285da822c1bf6f97871 750 SUPERFAMILY SSF53223 11 161 1.44E-50 T 14-10-2018 LH59_22620 3c98628b97a29285da822c1bf6f97871 750 Gene3D G3DSA:3.40.50.720 161 442 5.7E-81 T 14-10-2018 LH59_22620 3c98628b97a29285da822c1bf6f97871 750 Gene3D G3DSA:3.40.50.10380 1 160 2.7E-67 T 14-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 LH59_22620 3c98628b97a29285da822c1bf6f97871 750 SMART SM00919 163 400 1.5E-135 T 14-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 LH59_22620 3c98628b97a29285da822c1bf6f97871 750 SMART SM01274 18 151 3.0E-76 T 14-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 LH59_22620 3c98628b97a29285da822c1bf6f97871 750 Pfam PF01515 Phosphate acetyl/butaryl transferase 429 743 5.0E-81 T 14-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 LH59_22620 3c98628b97a29285da822c1bf6f97871 750 SUPERFAMILY SSF51735 163 438 1.84E-84 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_22620 3c98628b97a29285da822c1bf6f97871 750 SUPERFAMILY SSF53659 429 746 6.17E-78 T 14-10-2018 LH59_22620 3c98628b97a29285da822c1bf6f97871 750 PIRSF PIRSF036684 1 750 0.0 T 14-10-2018 IPR012188 NAD(P)-dependent malic enzyme GO:0004470|GO:0006108|GO:0046872 KEGG: 00620+1.1.1.40|KEGG: 00710+1.1.1.40|MetaCyc: PWY-241|MetaCyc: PWY-7117 LH59_22620 3c98628b97a29285da822c1bf6f97871 750 Pfam PF00390 Malic enzyme, N-terminal domain 19 151 1.0E-25 T 14-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 LH59_03975 1097fc4c95265eca9e2b74405a527ce1 201 Pfam PF01810 LysE type translocator 17 200 2.0E-19 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 LH59_24130 5d8366a84c2459a08489611e4aacc45e 398 SUPERFAMILY SSF89796 7 394 5.76E-137 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily LH59_24130 5d8366a84c2459a08489611e4aacc45e 398 Pfam PF02515 CoA-transferase family III 9 384 4.6E-130 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 LH59_24130 5d8366a84c2459a08489611e4aacc45e 398 Gene3D G3DSA:3.30.1540.10 237 328 2.0E-139 T 14-10-2018 LH59_24130 5d8366a84c2459a08489611e4aacc45e 398 Gene3D G3DSA:3.40.50.10540 9 347 2.0E-139 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily LH59_11315 860a60e2239431c91bb80409f7740cd4 126 SMART SM00448 3 116 2.4E-34 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_11315 860a60e2239431c91bb80409f7740cd4 126 Pfam PF00072 Response regulator receiver domain 5 114 1.2E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_11315 860a60e2239431c91bb80409f7740cd4 126 SUPERFAMILY SSF52172 4 121 7.68E-37 T 14-10-2018 IPR011006 CheY-like superfamily LH59_11315 860a60e2239431c91bb80409f7740cd4 126 Gene3D G3DSA:3.40.50.12740 1 125 1.2E-37 T 14-10-2018 LH59_08905 8c222dc9e5e6b95a6a179341625b0ef1 475 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 8 458 2.2E-119 T 14-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 LH59_08905 8c222dc9e5e6b95a6a179341625b0ef1 475 SUPERFAMILY SSF56954 1 460 1.19E-94 T 14-10-2018 LH59_08905 8c222dc9e5e6b95a6a179341625b0ef1 475 Gene3D G3DSA:1.20.1600.10 47 459 6.8E-109 T 14-10-2018 LH59_08905 8c222dc9e5e6b95a6a179341625b0ef1 475 Pfam PF02321 Outer membrane efflux protein 280 451 3.1E-22 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 LH59_08905 8c222dc9e5e6b95a6a179341625b0ef1 475 Pfam PF02321 Outer membrane efflux protein 57 248 6.2E-25 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 LH59_08905 8c222dc9e5e6b95a6a179341625b0ef1 475 Gene3D G3DSA:2.20.200.10 94 347 6.8E-109 T 14-10-2018 LH59_06875 93855c5326a56753f6f87c815cb4eddf 296 Pfam PF13714 Phosphoenolpyruvate phosphomutase 12 255 5.8E-53 T 14-10-2018 LH59_06875 93855c5326a56753f6f87c815cb4eddf 296 SUPERFAMILY SSF51621 5 291 1.93E-101 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 LH59_06875 93855c5326a56753f6f87c815cb4eddf 296 ProSitePatterns PS00161 Isocitrate lyase signature. 122 127 - T 14-10-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824 LH59_06875 93855c5326a56753f6f87c815cb4eddf 296 TIGRFAM TIGR02317 prpB: methylisocitrate lyase 8 292 8.5E-127 T 14-10-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 LH59_06875 93855c5326a56753f6f87c815cb4eddf 296 Hamap MF_01939 2-methylisocitrate lyase [prpB]. 5 293 48.521 T 14-10-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 LH59_06875 93855c5326a56753f6f87c815cb4eddf 296 Gene3D G3DSA:3.20.20.60 5 296 1.2E-103 T 14-10-2018 LH59_28165 0d961fbb55f5b3e42df09dfaaec81a35 225 Pfam PF00072 Response regulator receiver domain 3 113 2.1E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_28165 0d961fbb55f5b3e42df09dfaaec81a35 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 219 2.3E-18 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_28165 0d961fbb55f5b3e42df09dfaaec81a35 225 SUPERFAMILY SSF52172 1 167 3.13E-34 T 14-10-2018 IPR011006 CheY-like superfamily LH59_28165 0d961fbb55f5b3e42df09dfaaec81a35 225 SMART SM00448 1 113 1.5E-32 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_28165 0d961fbb55f5b3e42df09dfaaec81a35 225 SMART SM00862 146 219 1.1E-15 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_28165 0d961fbb55f5b3e42df09dfaaec81a35 225 Gene3D G3DSA:1.10.10.10 125 224 4.2E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_28165 0d961fbb55f5b3e42df09dfaaec81a35 225 Gene3D G3DSA:3.40.50.2300 1 122 2.0E-31 T 14-10-2018 LH59_15900 a72d3218115e41057db2ed142b12501a 296 SUPERFAMILY SSF46785 2 82 1.13E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_15900 a72d3218115e41057db2ed142b12501a 296 SUPERFAMILY SSF53850 89 293 5.43E-36 T 14-10-2018 LH59_15900 a72d3218115e41057db2ed142b12501a 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 2.6E-16 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_15900 a72d3218115e41057db2ed142b12501a 296 Pfam PF03466 LysR substrate binding domain 92 294 1.3E-22 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_15900 a72d3218115e41057db2ed142b12501a 296 Gene3D G3DSA:3.40.190.10 169 265 2.3E-57 T 14-10-2018 LH59_15900 a72d3218115e41057db2ed142b12501a 296 Gene3D G3DSA:1.10.10.10 1 84 6.1E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_15900 a72d3218115e41057db2ed142b12501a 296 Gene3D G3DSA:3.40.190.10 90 289 2.3E-57 T 14-10-2018 LH59_14860 a9dbea5d8a0c41976b3903e49f2f908a 130 Pfam PF12680 SnoaL-like domain 12 113 2.7E-24 T 14-10-2018 IPR037401 SnoaL-like domain LH59_14860 a9dbea5d8a0c41976b3903e49f2f908a 130 Gene3D G3DSA:3.10.450.50 1 122 2.3E-31 T 14-10-2018 LH59_14860 a9dbea5d8a0c41976b3903e49f2f908a 130 SUPERFAMILY SSF54427 8 125 5.79E-30 T 14-10-2018 IPR032710 NTF2-like domain superfamily LH59_11320 82ccfd1b4620f347540d5d6ca7d84c10 713 Pfam PF01584 CheW-like domain 571 699 2.5E-27 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 LH59_11320 82ccfd1b4620f347540d5d6ca7d84c10 713 SMART SM00387 426 566 1.3E-26 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_11320 82ccfd1b4620f347540d5d6ca7d84c10 713 SUPERFAMILY SSF55874 384 564 3.67E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_11320 82ccfd1b4620f347540d5d6ca7d84c10 713 Gene3D G3DSA:2.40.50.180 589 653 1.6E-39 T 14-10-2018 LH59_11320 82ccfd1b4620f347540d5d6ca7d84c10 713 SMART SM01231 318 381 5.8E-21 T 14-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 LH59_11320 82ccfd1b4620f347540d5d6ca7d84c10 713 Gene3D G3DSA:3.30.70.400 171 251 4.4E-18 T 14-10-2018 IPR035891 CheY-binding domain of CheA LH59_11320 82ccfd1b4620f347540d5d6ca7d84c10 713 SMART SM00260 558 698 1.1E-41 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 LH59_11320 82ccfd1b4620f347540d5d6ca7d84c10 713 SUPERFAMILY SSF50341 565 697 1.05E-31 T 14-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 LH59_11320 82ccfd1b4620f347540d5d6ca7d84c10 713 Gene3D G3DSA:1.20.120.160 4 144 3.3E-43 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 LH59_11320 82ccfd1b4620f347540d5d6ca7d84c10 713 Gene3D G3DSA:1.10.287.560 318 381 2.4E-16 T 14-10-2018 IPR037006 Histidine kinase CheA-like, homodimeric domain superfamily GO:0000155|GO:0006935 LH59_11320 82ccfd1b4620f347540d5d6ca7d84c10 713 Gene3D G3DSA:2.30.30.40 566 694 1.6E-39 T 14-10-2018 LH59_11320 82ccfd1b4620f347540d5d6ca7d84c10 713 Pfam PF09078 CheY binding 187 249 2.3E-25 T 14-10-2018 IPR015162 CheY binding LH59_11320 82ccfd1b4620f347540d5d6ca7d84c10 713 SUPERFAMILY SSF47226 7 129 8.13E-31 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 LH59_11320 82ccfd1b4620f347540d5d6ca7d84c10 713 Gene3D G3DSA:3.30.565.10 382 565 4.0E-53 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_11320 82ccfd1b4620f347540d5d6ca7d84c10 713 SUPERFAMILY SSF47384 319 382 2.31E-15 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 LH59_11320 82ccfd1b4620f347540d5d6ca7d84c10 713 SUPERFAMILY SSF55052 186 251 2.43E-20 T 14-10-2018 IPR035891 CheY-binding domain of CheA LH59_11320 82ccfd1b4620f347540d5d6ca7d84c10 713 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 429 565 4.2E-17 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_11320 82ccfd1b4620f347540d5d6ca7d84c10 713 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 319 381 2.3E-16 T 14-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 LH59_11320 82ccfd1b4620f347540d5d6ca7d84c10 713 SMART SM00073 7 105 6.7E-29 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 LH59_11320 82ccfd1b4620f347540d5d6ca7d84c10 713 PRINTS PR00344 Bacterial sensor protein C-terminal signature 510 520 4.0E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_11320 82ccfd1b4620f347540d5d6ca7d84c10 713 PRINTS PR00344 Bacterial sensor protein C-terminal signature 471 485 4.0E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_11320 82ccfd1b4620f347540d5d6ca7d84c10 713 PRINTS PR00344 Bacterial sensor protein C-terminal signature 526 544 4.0E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_11320 82ccfd1b4620f347540d5d6ca7d84c10 713 PRINTS PR00344 Bacterial sensor protein C-terminal signature 550 563 4.0E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_11320 82ccfd1b4620f347540d5d6ca7d84c10 713 Pfam PF01627 Hpt domain 10 110 1.2E-17 T 14-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 LH59_17295 4deaf09324430fe6190ff9c84369f8fe 305 SUPERFAMILY SSF53850 91 299 2.17E-36 T 14-10-2018 LH59_17295 4deaf09324430fe6190ff9c84369f8fe 305 Gene3D G3DSA:1.10.10.10 2 85 2.8E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_17295 4deaf09324430fe6190ff9c84369f8fe 305 Pfam PF03466 LysR substrate binding domain 90 294 2.1E-34 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_17295 4deaf09324430fe6190ff9c84369f8fe 305 Gene3D G3DSA:3.40.190.10 92 291 1.4E-55 T 14-10-2018 LH59_17295 4deaf09324430fe6190ff9c84369f8fe 305 SUPERFAMILY SSF46785 2 111 2.0E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_17295 4deaf09324430fe6190ff9c84369f8fe 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 4.3E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_17295 4deaf09324430fe6190ff9c84369f8fe 305 Gene3D G3DSA:3.40.190.10 163 266 1.4E-55 T 14-10-2018 LH59_05200 7ef928b225a517b6a120622487a36f59 310 SUPERFAMILY SSF46785 5 84 2.28E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_05200 7ef928b225a517b6a120622487a36f59 310 Pfam PF03466 LysR substrate binding domain 88 292 6.1E-53 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_05200 7ef928b225a517b6a120622487a36f59 310 Gene3D G3DSA:3.40.190.10 163 263 5.0E-74 T 14-10-2018 LH59_05200 7ef928b225a517b6a120622487a36f59 310 Gene3D G3DSA:1.10.10.10 3 89 2.8E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_05200 7ef928b225a517b6a120622487a36f59 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 3.4E-15 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_05200 7ef928b225a517b6a120622487a36f59 310 SUPERFAMILY SSF53850 90 294 8.69E-54 T 14-10-2018 LH59_05200 7ef928b225a517b6a120622487a36f59 310 Gene3D G3DSA:3.40.190.10 91 288 5.0E-74 T 14-10-2018 LH59_18905 f0e08194c90a2ebfea202db35647f331 161 Pfam PF10722 Putative bacterial sensory transduction regulator 12 130 2.7E-8 T 14-10-2018 IPR019660 Putative sensory transduction regulator YbjN LH59_16620 5848671b230e957591a19114a0a59983 1349 SUPERFAMILY SSF52317 1088 1348 4.58E-86 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_16620 5848671b230e957591a19114a0a59983 1349 SMART SM01211 1091 1348 5.0E-136 T 14-10-2018 LH59_16620 5848671b230e957591a19114a0a59983 1349 SUPERFAMILY SSF56042 445 683 1.64E-47 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily LH59_16620 5848671b230e957591a19114a0a59983 1349 Gene3D G3DSA:3.40.50.880 1033 1349 1.2E-121 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_16620 5848671b230e957591a19114a0a59983 1349 SUPERFAMILY SSF55326 648 843 3.4E-64 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily LH59_16620 5848671b230e957591a19114a0a59983 1349 Hamap MF_00419 Phosphoribosylformylglycinamidine synthase [purL]. 4 1349 20.497 T 14-10-2018 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 LH59_16620 5848671b230e957591a19114a0a59983 1349 Gene3D G3DSA:1.10.8.750 164 223 2.5E-25 T 14-10-2018 LH59_16620 5848671b230e957591a19114a0a59983 1349 Pfam PF02769 AIR synthase related protein, C-terminal domain 854 1017 7.3E-14 T 14-10-2018 IPR010918 PurM-like, C-terminal domain LH59_16620 5848671b230e957591a19114a0a59983 1349 Pfam PF02769 AIR synthase related protein, C-terminal domain 447 604 6.4E-27 T 14-10-2018 IPR010918 PurM-like, C-terminal domain LH59_16620 5848671b230e957591a19114a0a59983 1349 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 1091 1348 4.8E-98 T 14-10-2018 LH59_16620 5848671b230e957591a19114a0a59983 1349 SUPERFAMILY SSF55326 231 437 2.44E-56 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily LH59_16620 5848671b230e957591a19114a0a59983 1349 SUPERFAMILY SSF56042 852 1084 8.22E-49 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily LH59_16620 5848671b230e957591a19114a0a59983 1349 SUPERFAMILY SSF82697 5 160 2.72E-43 T 14-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 LH59_16620 5848671b230e957591a19114a0a59983 1349 Gene3D G3DSA:3.90.650.10 836 1032 1.3E-29 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily LH59_16620 5848671b230e957591a19114a0a59983 1349 Gene3D G3DSA:3.30.1330.10 224 432 4.9E-39 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily LH59_16620 5848671b230e957591a19114a0a59983 1349 SUPERFAMILY SSF109736 165 230 7.72E-21 T 14-10-2018 LH59_16620 5848671b230e957591a19114a0a59983 1349 Gene3D G3DSA:3.30.1330.10 650 835 1.6E-21 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily LH59_16620 5848671b230e957591a19114a0a59983 1349 TIGRFAM TIGR01735 FGAM_synt: phosphoribosylformylglycinamidine synthase 9 1348 0.0 T 14-10-2018 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 LH59_16620 5848671b230e957591a19114a0a59983 1349 Gene3D G3DSA:3.90.650.10 433 610 2.5E-54 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily LH59_22110 cdee1a77f8936c27ccfa6f1f2e7381ec 84 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 5 64 4.3E-7 T 14-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM LH59_22110 cdee1a77f8936c27ccfa6f1f2e7381ec 84 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 25 54 3.1E-5 T 14-10-2018 LH59_22110 cdee1a77f8936c27ccfa6f1f2e7381ec 84 SUPERFAMILY SSF143120 4 72 4.58E-10 T 14-10-2018 IPR036165 YefM-like superfamily LH59_14680 168ffd62ea63a6ba911f77ec5664b0fc 243 SMART SM00862 155 231 1.1E-28 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_14680 168ffd62ea63a6ba911f77ec5664b0fc 243 SMART SM00448 5 116 6.8E-41 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_14680 168ffd62ea63a6ba911f77ec5664b0fc 243 SUPERFAMILY SSF46894 128 232 2.67E-30 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LH59_14680 168ffd62ea63a6ba911f77ec5664b0fc 243 Pfam PF00072 Response regulator receiver domain 7 116 6.2E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_14680 168ffd62ea63a6ba911f77ec5664b0fc 243 SUPERFAMILY SSF52172 3 129 4.98E-41 T 14-10-2018 IPR011006 CheY-like superfamily LH59_14680 168ffd62ea63a6ba911f77ec5664b0fc 243 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 231 3.5E-27 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_14680 168ffd62ea63a6ba911f77ec5664b0fc 243 Gene3D G3DSA:3.40.50.2300 1 122 6.6E-37 T 14-10-2018 LH59_14680 168ffd62ea63a6ba911f77ec5664b0fc 243 Gene3D G3DSA:1.10.10.10 123 235 2.5E-36 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_17955 52d7c292f87a74de6b4e9866413d7a85 745 Pfam PF07095 Intracellular growth attenuator protein IgaA 14 733 2.2E-34 T 14-10-2018 IPR010771 Intracellular growth attenuator IgaA GO:0009276|GO:0016021 LH59_17955 52d7c292f87a74de6b4e9866413d7a85 745 ProDom PD147088 MEMBRANE INNER TRANSMEMBRANE IGAA HOMOLOG DEHYDROGENASE GROWTH ATTENUATOR INTRACELLULAR GENOME 75 678 2.0E-10 T 14-10-2018 IPR010771 Intracellular growth attenuator IgaA GO:0009276|GO:0016021 LH59_00560 974984c9ed514c0957a99044cf8db21b 535 Gene3D G3DSA:3.90.226.10 274 535 2.3E-105 T 14-10-2018 LH59_00560 974984c9ed514c0957a99044cf8db21b 535 SUPERFAMILY SSF52096 22 270 2.09E-70 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily LH59_00560 974984c9ed514c0957a99044cf8db21b 535 Pfam PF01039 Carboxyl transferase domain 48 525 1.8E-152 T 14-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 LH59_00560 974984c9ed514c0957a99044cf8db21b 535 Gene3D G3DSA:3.90.226.10 1 271 2.1E-95 T 14-10-2018 LH59_00560 974984c9ed514c0957a99044cf8db21b 535 SUPERFAMILY SSF52096 237 517 3.25E-88 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily LH59_24475 c40aea70df21ccdc67125163aa85ac9a 406 TIGRFAM TIGR00843 benE: benzoate transporter 24 397 1.7E-105 T 14-10-2018 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 LH59_24475 c40aea70df21ccdc67125163aa85ac9a 406 Pfam PF03594 Benzoate membrane transport protein 21 397 1.5E-131 T 14-10-2018 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 LH59_25505 f8a0eb5fbefb37f7c5b350278a62bd22 727 Pfam PF00593 TonB dependent receptor 237 725 3.2E-46 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_25505 f8a0eb5fbefb37f7c5b350278a62bd22 727 Pfam PF07715 TonB-dependent Receptor Plug Domain 61 160 2.7E-21 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_25505 f8a0eb5fbefb37f7c5b350278a62bd22 727 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 710 727 - T 14-10-2018 IPR010917 TonB-dependent receptor, conserved site LH59_25505 f8a0eb5fbefb37f7c5b350278a62bd22 727 SUPERFAMILY SSF56935 28 727 8.25E-117 T 14-10-2018 LH59_25505 f8a0eb5fbefb37f7c5b350278a62bd22 727 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 63 727 3.4E-82 T 14-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 LH59_25505 f8a0eb5fbefb37f7c5b350278a62bd22 727 Gene3D G3DSA:2.170.130.10 40 167 4.9E-31 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily LH59_25505 f8a0eb5fbefb37f7c5b350278a62bd22 727 Gene3D G3DSA:2.40.170.20 175 727 7.2E-94 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_08675 226f320b92b69f43c10aed9ae4636388 554 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 184 282 4.8E-14 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 LH59_08675 226f320b92b69f43c10aed9ae4636388 554 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 405 424 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 LH59_08675 226f320b92b69f43c10aed9ae4636388 554 SUPERFAMILY SSF47203 299 449 1.32E-41 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 LH59_08675 226f320b92b69f43c10aed9ae4636388 554 SUPERFAMILY SSF56645 59 289 2.4E-31 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 LH59_08675 226f320b92b69f43c10aed9ae4636388 554 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 292 446 1.4E-32 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LH59_08675 226f320b92b69f43c10aed9ae4636388 554 Gene3D G3DSA:1.20.140.10 293 448 5.6E-37 T 14-10-2018 LH59_08675 226f320b92b69f43c10aed9ae4636388 554 Gene3D G3DSA:2.40.110.20 130 292 3.0E-50 T 14-10-2018 LH59_23150 0b9cae6f7fbb67ea8aff802ea756abf5 201 Gene3D G3DSA:1.20.144.10 92 185 1.8E-18 T 14-10-2018 LH59_23150 0b9cae6f7fbb67ea8aff802ea756abf5 201 SMART SM00014 58 168 1.2E-9 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase LH59_23150 0b9cae6f7fbb67ea8aff802ea756abf5 201 Pfam PF01569 PAP2 superfamily 60 168 4.0E-13 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase LH59_23150 0b9cae6f7fbb67ea8aff802ea756abf5 201 SUPERFAMILY SSF48317 5 174 6.93E-30 T 14-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily LH59_04295 117b74c4890f806394e88156cff99c18 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 2.9E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_04295 117b74c4890f806394e88156cff99c18 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 2.9E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_04295 117b74c4890f806394e88156cff99c18 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 2.9E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_04295 117b74c4890f806394e88156cff99c18 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 193 3.7E-4 T 14-10-2018 LH59_04295 117b74c4890f806394e88156cff99c18 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 246 4.1E-60 T 14-10-2018 LH59_04295 117b74c4890f806394e88156cff99c18 248 Gene3D G3DSA:3.40.50.720 1 247 9.6E-80 T 14-10-2018 LH59_04295 117b74c4890f806394e88156cff99c18 248 SUPERFAMILY SSF51735 1 247 2.07E-77 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_04295 117b74c4890f806394e88156cff99c18 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 8.7E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_04295 117b74c4890f806394e88156cff99c18 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 8.7E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_04295 117b74c4890f806394e88156cff99c18 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 8.7E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_04295 117b74c4890f806394e88156cff99c18 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 8.7E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_04295 117b74c4890f806394e88156cff99c18 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 8.7E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_04295 117b74c4890f806394e88156cff99c18 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 8.7E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_27250 48490a4fc59dcd9b7268904ee5802d60 201 SUPERFAMILY SSF159594 31 193 9.68E-26 T 14-10-2018 LH59_27250 48490a4fc59dcd9b7268904ee5802d60 201 Gene3D G3DSA:3.40.50.10610 23 199 4.3E-22 T 14-10-2018 LH59_27250 48490a4fc59dcd9b7268904ee5802d60 201 Pfam PF03886 ABC-type transport auxiliary lipoprotein component 57 186 2.8E-11 T 14-10-2018 IPR005586 ABC-type transport auxiliary lipoprotein component LH59_02355 a0928cbf64b65acc6f4583f0e5625e5a 311 Gene3D G3DSA:3.40.50.720 4 308 3.7E-103 T 14-10-2018 LH59_02355 a0928cbf64b65acc6f4583f0e5625e5a 311 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 194 216 - T 14-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site LH59_02355 a0928cbf64b65acc6f4583f0e5625e5a 311 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 107 284 7.3E-58 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 LH59_02355 a0928cbf64b65acc6f4583f0e5625e5a 311 SUPERFAMILY SSF52283 1 131 2.76E-31 T 14-10-2018 LH59_02355 a0928cbf64b65acc6f4583f0e5625e5a 311 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 223 239 - T 14-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site LH59_02355 a0928cbf64b65acc6f4583f0e5625e5a 311 SUPERFAMILY SSF51735 97 285 1.85E-57 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_02355 a0928cbf64b65acc6f4583f0e5625e5a 311 Gene3D G3DSA:3.40.50.720 97 282 3.7E-103 T 14-10-2018 LH59_02355 a0928cbf64b65acc6f4583f0e5625e5a 311 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 3 309 2.0E-25 T 14-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 LH59_02355 a0928cbf64b65acc6f4583f0e5625e5a 311 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 144 171 - T 14-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 LH59_16660 6742c714c12c920610137c7ea4ce3933 392 PIRSF PIRSF003085 23 391 8.2E-121 T 14-10-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 LH59_16660 6742c714c12c920610137c7ea4ce3933 392 Gene3D G3DSA:3.40.50.150 126 385 1.3E-98 T 14-10-2018 LH59_16660 6742c714c12c920610137c7ea4ce3933 392 SUPERFAMILY SSF53335 126 382 1.51E-78 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_16660 6742c714c12c920610137c7ea4ce3933 392 Pfam PF02353 Mycolic acid cyclopropane synthetase 117 377 4.9E-95 T 14-10-2018 LH59_22610 e3a65653e39b8b4acbd83b43172dd34f 155 Pfam PF01337 Barstar (barnase inhibitor) 43 123 3.9E-21 T 14-10-2018 IPR000468 Barstar (barnase inhibitor) LH59_22610 e3a65653e39b8b4acbd83b43172dd34f 155 SUPERFAMILY SSF52038 41 128 2.35E-18 T 14-10-2018 IPR035905 Barstar-like superfamily LH59_22610 e3a65653e39b8b4acbd83b43172dd34f 155 Gene3D G3DSA:3.30.370.10 41 126 2.4E-9 T 14-10-2018 IPR035905 Barstar-like superfamily LH59_20945 b6ac2bf37177f50b3fa0fa3e7094aec8 338 PRINTS PR00184 Neisseria sp. porin signature 59 84 1.6E-5 T 14-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 LH59_20945 b6ac2bf37177f50b3fa0fa3e7094aec8 338 PRINTS PR00184 Neisseria sp. porin signature 296 320 1.6E-5 T 14-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 LH59_20945 b6ac2bf37177f50b3fa0fa3e7094aec8 338 Gene3D G3DSA:2.40.160.10 29 338 6.6E-80 T 14-10-2018 IPR023614 Porin domain superfamily LH59_20945 b6ac2bf37177f50b3fa0fa3e7094aec8 338 SUPERFAMILY SSF56935 29 338 3.89E-68 T 14-10-2018 LH59_20945 b6ac2bf37177f50b3fa0fa3e7094aec8 338 Pfam PF13609 Gram-negative porin 13 321 2.6E-54 T 14-10-2018 LH59_14130 d56f17d0b6d634d0cbd2e72ba434f984 268 SUPERFAMILY SSF52540 10 236 1.09E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_14130 d56f17d0b6d634d0cbd2e72ba434f984 268 Pfam PF00005 ABC transporter 26 174 5.3E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_14130 d56f17d0b6d634d0cbd2e72ba434f984 268 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_14130 d56f17d0b6d634d0cbd2e72ba434f984 268 Gene3D G3DSA:3.40.50.300 4 262 3.1E-71 T 14-10-2018 LH59_14130 d56f17d0b6d634d0cbd2e72ba434f984 268 SMART SM00382 35 223 7.2E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_25550 0b4b703cc0feda4fecf401c558ccfab7 93 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 30 50 - T 14-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 LH59_25550 0b4b703cc0feda4fecf401c558ccfab7 93 SUPERFAMILY SSF54534 4 92 5.44E-30 T 14-10-2018 LH59_25550 0b4b703cc0feda4fecf401c558ccfab7 93 Gene3D G3DSA:3.10.50.40 2 92 6.1E-37 T 14-10-2018 LH59_25550 0b4b703cc0feda4fecf401c558ccfab7 93 Pfam PF13616 PPIC-type PPIASE domain 4 92 4.2E-26 T 14-10-2018 LH59_19420 7294d79fb62d07ec50c806e33a76c3b9 470 Pfam PF00324 Amino acid permease 17 428 8.2E-100 T 14-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 LH59_19420 7294d79fb62d07ec50c806e33a76c3b9 470 Gene3D G3DSA:1.20.1740.10 11 461 2.8E-59 T 14-10-2018 LH59_19420 7294d79fb62d07ec50c806e33a76c3b9 470 PIRSF PIRSF006060 2 467 5.2E-70 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 LH59_24410 0b60141790720820828122ac0aeb7300 391 Pfam PF00925 GTP cyclohydrolase II 225 379 8.7E-33 T 14-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 LH59_24410 0b60141790720820828122ac0aeb7300 391 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 16 218 38.298 T 14-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 LH59_24410 0b60141790720820828122ac0aeb7300 391 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 19 214 2.4E-73 T 14-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 LH59_24410 0b60141790720820828122ac0aeb7300 391 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 23 213 1.1E-81 T 14-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 LH59_24410 0b60141790720820828122ac0aeb7300 391 Gene3D G3DSA:3.90.870.10 11 220 2.9E-88 T 14-10-2018 LH59_24410 0b60141790720820828122ac0aeb7300 391 SUPERFAMILY SSF142695 220 380 3.27E-41 T 14-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 LH59_24410 0b60141790720820828122ac0aeb7300 391 PIRSF PIRSF001259 17 386 5.3E-113 T 14-10-2018 LH59_24410 0b60141790720820828122ac0aeb7300 391 SUPERFAMILY SSF55821 16 218 3.2E-85 T 14-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily LH59_24410 0b60141790720820828122ac0aeb7300 391 Gene3D G3DSA:3.40.50.10990 221 380 4.2E-21 T 14-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 LH59_23725 3e84355f4ce28bb4ae485b3e83036c1d 132 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 32 105 9.7E-18 T 14-10-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 LH59_23725 3e84355f4ce28bb4ae485b3e83036c1d 132 TIGRFAM TIGR02847 CyoD: cytochrome o ubiquinol oxidase subunit IV 25 121 1.9E-34 T 14-10-2018 IPR014210 Cytochrome o ubiquinol oxidase subunit IV GO:0008827|GO:0015990|GO:0016021 LH59_00205 73c839496891c228bf491c3f2abeff94 102 SUPERFAMILY SSF54292 17 94 1.57E-17 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 LH59_00205 73c839496891c228bf491c3f2abeff94 102 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 15 94 2.1E-25 T 14-10-2018 LH59_00205 73c839496891c228bf491c3f2abeff94 102 Gene3D G3DSA:3.10.20.440 2 101 9.2E-19 T 14-10-2018 LH59_17260 d6e9d483e3c53f64e04a63b8e5624222 67 Gene3D G3DSA:2.40.50.140 1 66 2.9E-26 T 14-10-2018 LH59_17260 d6e9d483e3c53f64e04a63b8e5624222 67 SMART SM00357 3 67 7.4E-28 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 LH59_17260 d6e9d483e3c53f64e04a63b8e5624222 67 PIRSF PIRSF002599 1 67 2.9E-21 T 14-10-2018 IPR012156 Cold shock, CspA GO:0003676 LH59_17260 d6e9d483e3c53f64e04a63b8e5624222 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 14-10-2018 IPR019844 Cold-shock conserved site LH59_17260 d6e9d483e3c53f64e04a63b8e5624222 67 SUPERFAMILY SSF50249 1 66 2.42E-22 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_17260 d6e9d483e3c53f64e04a63b8e5624222 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 6.6E-27 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 LH59_17260 d6e9d483e3c53f64e04a63b8e5624222 67 PRINTS PR00050 Cold shock protein signature 4 19 1.6E-12 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 LH59_17260 d6e9d483e3c53f64e04a63b8e5624222 67 PRINTS PR00050 Cold shock protein signature 40 58 1.6E-12 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 LH59_17260 d6e9d483e3c53f64e04a63b8e5624222 67 PRINTS PR00050 Cold shock protein signature 25 34 1.6E-12 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 LH59_20290 32a644fe586836895afdbb81eec90f57 317 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 136 208 2.0E-12 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_20290 32a644fe586836895afdbb81eec90f57 317 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 221 296 5.3E-12 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_20290 32a644fe586836895afdbb81eec90f57 317 SUPERFAMILY SSF46626 216 310 1.4E-23 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_20290 32a644fe586836895afdbb81eec90f57 317 Gene3D G3DSA:1.10.760.10 189 276 6.8E-71 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_20290 32a644fe586836895afdbb81eec90f57 317 Gene3D G3DSA:1.20.58.1490 5 101 7.9E-27 T 14-10-2018 IPR038414 Cbb3-type cytochrome c oxidase subunit CcoP, N-terminal domain superfamily LH59_20290 32a644fe586836895afdbb81eec90f57 317 SUPERFAMILY SSF46626 64 218 9.16E-29 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_20290 32a644fe586836895afdbb81eec90f57 317 PIRSF PIRSF000006 5 303 4.3E-97 T 14-10-2018 IPR004678 Cytochrome c oxidase cbb3-type, subunit III LH59_20290 32a644fe586836895afdbb81eec90f57 317 TIGRFAM TIGR00782 ccoP: cytochrome c oxidase, cbb3-type, subunit III 43 302 3.5E-76 T 14-10-2018 IPR004678 Cytochrome c oxidase cbb3-type, subunit III LH59_20290 32a644fe586836895afdbb81eec90f57 317 Gene3D G3DSA:1.10.760.10 111 299 6.8E-71 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_20290 32a644fe586836895afdbb81eec90f57 317 Pfam PF14715 N-terminal domain of cytochrome oxidase-cbb3, FixP 45 91 5.3E-19 T 14-10-2018 IPR032858 Cbb3-type cytochrome c oxidase subunit CcoP, N-terminal LH59_25420 fbb4310f495404a4d366445c40c273fd 448 ProSitePatterns PS00543 HlyD family secretion proteins signature. 412 434 - T 14-10-2018 IPR006144 Secretion protein HlyD, conserved site GO:0008565|GO:0009306|GO:0016020 LH59_25420 fbb4310f495404a4d366445c40c273fd 448 Gene3D G3DSA:2.40.30.170 337 416 6.0E-12 T 14-10-2018 LH59_25420 fbb4310f495404a4d366445c40c273fd 448 TIGRFAM TIGR01843 type_I_hlyD: type I secretion membrane fusion protein, HlyD family 33 444 1.2E-119 T 14-10-2018 IPR010129 Type I secretion membrane fusion protein, HlyD family GO:0015031|GO:0016021 LH59_25420 fbb4310f495404a4d366445c40c273fd 448 Gene3D G3DSA:1.10.287.470 105 184 2.8E-6 T 14-10-2018 LH59_25420 fbb4310f495404a4d366445c40c273fd 448 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 345 369 3.4E-60 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 LH59_25420 fbb4310f495404a4d366445c40c273fd 448 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 427 447 3.4E-60 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 LH59_25420 fbb4310f495404a4d366445c40c273fd 448 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 41 64 3.4E-60 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 LH59_25420 fbb4310f495404a4d366445c40c273fd 448 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 412 427 3.4E-60 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 LH59_25420 fbb4310f495404a4d366445c40c273fd 448 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 312 333 3.4E-60 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 LH59_25420 fbb4310f495404a4d366445c40c273fd 448 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 83 103 3.4E-60 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 LH59_25420 fbb4310f495404a4d366445c40c273fd 448 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 369 392 3.4E-60 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 LH59_25420 fbb4310f495404a4d366445c40c273fd 448 Pfam PF00529 HlyD membrane-fusion protein of T1SS 43 404 1.8E-16 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 LH59_25420 fbb4310f495404a4d366445c40c273fd 448 Gene3D G3DSA:2.40.50.100 300 336 6.0E-12 T 14-10-2018 LH59_25420 fbb4310f495404a4d366445c40c273fd 448 Gene3D G3DSA:1.10.287.470 232 299 6.0E-12 T 14-10-2018 LH59_25420 fbb4310f495404a4d366445c40c273fd 448 Gene3D G3DSA:2.40.50.100 73 104 2.8E-6 T 14-10-2018 LH59_01730 2d499b92d22ec4ae184b55f9573e7f64 215 Gene3D G3DSA:1.20.950.20 5 215 9.9E-64 T 14-10-2018 LH59_01730 2d499b92d22ec4ae184b55f9573e7f64 215 Pfam PF01292 Prokaryotic cytochrome b561 12 189 1.4E-25 T 14-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 LH59_01730 2d499b92d22ec4ae184b55f9573e7f64 215 SUPERFAMILY SSF81342 6 211 5.18E-53 T 14-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 LH59_01730 2d499b92d22ec4ae184b55f9573e7f64 215 TIGRFAM TIGR01583 formate-DH-gamm: formate dehydrogenase, gamma subunit 9 207 1.7E-59 T 14-10-2018 IPR006471 Formate dehydrogenase, gamma subunit GO:0008863|GO:0009326|GO:0016021|GO:0045333 LH59_23380 7b82081d4e0bd146a0de2450e3acd2b9 764 SMART SM01274 19 152 6.6E-75 T 14-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 LH59_23380 7b82081d4e0bd146a0de2450e3acd2b9 764 Gene3D G3DSA:3.40.50.10950 447 759 5.2E-97 T 14-10-2018 LH59_23380 7b82081d4e0bd146a0de2450e3acd2b9 764 SUPERFAMILY SSF53223 11 162 3.38E-50 T 14-10-2018 LH59_23380 7b82081d4e0bd146a0de2450e3acd2b9 764 Pfam PF00390 Malic enzyme, N-terminal domain 20 152 6.7E-25 T 14-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 LH59_23380 7b82081d4e0bd146a0de2450e3acd2b9 764 SUPERFAMILY SSF53659 430 761 2.59E-86 T 14-10-2018 LH59_23380 7b82081d4e0bd146a0de2450e3acd2b9 764 Pfam PF01515 Phosphate acetyl/butaryl transferase 430 756 1.3E-94 T 14-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 LH59_23380 7b82081d4e0bd146a0de2450e3acd2b9 764 Gene3D G3DSA:3.40.50.10380 1 161 3.7E-66 T 14-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 LH59_23380 7b82081d4e0bd146a0de2450e3acd2b9 764 Pfam PF03949 Malic enzyme, NAD binding domain 166 361 3.4E-19 T 14-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 LH59_23380 7b82081d4e0bd146a0de2450e3acd2b9 764 SMART SM00919 164 401 5.2E-133 T 14-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 LH59_23380 7b82081d4e0bd146a0de2450e3acd2b9 764 SUPERFAMILY SSF51735 164 439 2.31E-83 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_23380 7b82081d4e0bd146a0de2450e3acd2b9 764 Gene3D G3DSA:3.40.50.10750 578 732 5.2E-97 T 14-10-2018 LH59_23380 7b82081d4e0bd146a0de2450e3acd2b9 764 Gene3D G3DSA:3.40.50.720 162 443 6.7E-80 T 14-10-2018 LH59_23380 7b82081d4e0bd146a0de2450e3acd2b9 764 PIRSF PIRSF036684 1 763 0.0 T 14-10-2018 IPR012188 NAD(P)-dependent malic enzyme GO:0004470|GO:0006108|GO:0046872 KEGG: 00620+1.1.1.40|KEGG: 00710+1.1.1.40|MetaCyc: PWY-241|MetaCyc: PWY-7117 LH59_02725 f54dd50cdc30f10749ff0727d0b68b6a 232 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 27 231 6.7E-52 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 LH59_02725 f54dd50cdc30f10749ff0727d0b68b6a 232 SUPERFAMILY SSF56529 20 231 1.7E-69 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 LH59_02725 f54dd50cdc30f10749ff0727d0b68b6a 232 Gene3D G3DSA:3.90.850.10 1 232 6.4E-86 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 LH59_07450 9561c7e9715fe0c96e0901a4207002bf 243 SUPERFAMILY SSF55811 69 229 1.62E-36 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 LH59_07450 9561c7e9715fe0c96e0901a4207002bf 243 Pfam PF00293 NUDIX domain 78 158 6.0E-15 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 LH59_07450 9561c7e9715fe0c96e0901a4207002bf 243 Gene3D G3DSA:3.90.79.10 53 234 3.5E-49 T 14-10-2018 LH59_09575 36fe7be0de899755eb0ca9b96c920947 571 SUPERFAMILY SSF52467 162 356 1.54E-36 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily LH59_09575 36fe7be0de899755eb0ca9b96c920947 571 SUPERFAMILY SSF52518 9 186 1.86E-50 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold LH59_09575 36fe7be0de899755eb0ca9b96c920947 571 Gene3D G3DSA:3.40.50.1220 191 358 7.5E-37 T 14-10-2018 LH59_09575 36fe7be0de899755eb0ca9b96c920947 571 Gene3D G3DSA:3.40.50.970 366 568 3.7E-54 T 14-10-2018 LH59_09575 36fe7be0de899755eb0ca9b96c920947 571 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 197 333 3.9E-29 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 LH59_09575 36fe7be0de899755eb0ca9b96c920947 571 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 10 176 1.8E-50 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 LH59_09575 36fe7be0de899755eb0ca9b96c920947 571 Gene3D G3DSA:3.40.50.970 4 183 2.9E-57 T 14-10-2018 LH59_09575 36fe7be0de899755eb0ca9b96c920947 571 SUPERFAMILY SSF52518 367 549 2.5E-52 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold LH59_09575 36fe7be0de899755eb0ca9b96c920947 571 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 391 541 1.2E-35 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 LH59_04205 37cde81650b4aa711d804396ef16f4e3 164 Pfam PF08281 Sigma-70, region 4 105 158 7.6E-13 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LH59_04205 37cde81650b4aa711d804396ef16f4e3 164 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 157 1.4E-12 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 LH59_04205 37cde81650b4aa711d804396ef16f4e3 164 SUPERFAMILY SSF88946 5 72 8.24E-8 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 LH59_04205 37cde81650b4aa711d804396ef16f4e3 164 Pfam PF04542 Sigma-70 region 2 11 74 8.4E-5 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 LH59_04205 37cde81650b4aa711d804396ef16f4e3 164 SUPERFAMILY SSF88659 101 161 2.06E-11 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like LH59_04205 37cde81650b4aa711d804396ef16f4e3 164 Gene3D G3DSA:1.10.10.10 87 162 5.6E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_03860 ea5ffb79e73f01fcadb35e1bfaa2d09e 313 SUPERFAMILY SSF46785 3 88 1.86E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_03860 ea5ffb79e73f01fcadb35e1bfaa2d09e 313 SUPERFAMILY SSF53850 89 298 9.77E-47 T 14-10-2018 LH59_03860 ea5ffb79e73f01fcadb35e1bfaa2d09e 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 3.1E-20 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_03860 ea5ffb79e73f01fcadb35e1bfaa2d09e 313 Pfam PF03466 LysR substrate binding domain 88 295 3.1E-43 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_03860 ea5ffb79e73f01fcadb35e1bfaa2d09e 313 Gene3D G3DSA:3.40.190.10 165 267 5.3E-66 T 14-10-2018 LH59_03860 ea5ffb79e73f01fcadb35e1bfaa2d09e 313 Gene3D G3DSA:3.40.190.10 92 292 5.3E-66 T 14-10-2018 LH59_03860 ea5ffb79e73f01fcadb35e1bfaa2d09e 313 Gene3D G3DSA:1.10.10.10 2 91 1.3E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_24315 6d0effd02b6089b522cb988916b27f9b 485 SUPERFAMILY SSF53720 3 484 2.23E-160 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 LH59_24315 6d0effd02b6089b522cb988916b27f9b 485 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 252 259 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 LH59_24315 6d0effd02b6089b522cb988916b27f9b 485 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 280 291 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 LH59_24315 6d0effd02b6089b522cb988916b27f9b 485 Gene3D G3DSA:3.40.309.10 256 450 8.6E-181 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 LH59_24315 6d0effd02b6089b522cb988916b27f9b 485 TIGRFAM TIGR03216 OH_muco_semi_DH: 2-hydroxymuconic semialdehyde dehydrogenase 6 485 7.9E-251 T 14-10-2018 IPR017628 2-hydroxymuconic semialdehyde dehydrogenase GO:0016620|GO:0055114 LH59_24315 6d0effd02b6089b522cb988916b27f9b 485 Gene3D G3DSA:3.40.605.10 19 472 8.6E-181 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 LH59_24315 6d0effd02b6089b522cb988916b27f9b 485 Pfam PF00171 Aldehyde dehydrogenase family 19 481 1.4E-158 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 LH59_26685 8840eb4c9a668200fa67968e6e520f3c 309 Gene3D G3DSA:3.40.1010.10 17 137 7.1E-38 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 LH59_26685 8840eb4c9a668200fa67968e6e520f3c 309 SUPERFAMILY SSF53790 30 251 4.06E-73 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 LH59_26685 8840eb4c9a668200fa67968e6e520f3c 309 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 108 119 - T 14-10-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 LH59_26685 8840eb4c9a668200fa67968e6e520f3c 309 PIRSF PIRSF005917 18 309 9.1E-94 T 14-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 LH59_26685 8840eb4c9a668200fa67968e6e520f3c 309 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 31 305 4.9E-69 T 14-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 LH59_26685 8840eb4c9a668200fa67968e6e520f3c 309 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 30 233 7.3E-30 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 LH59_26685 8840eb4c9a668200fa67968e6e520f3c 309 Gene3D G3DSA:3.30.950.10 138 260 5.2E-36 T 14-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 LH59_26685 8840eb4c9a668200fa67968e6e520f3c 309 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 30 254 33.257 T 14-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 LH59_06915 11086b48def1656cfa50e3747137a4e4 436 SUPERFAMILY SSF48256 10 436 7.07E-161 T 14-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 LH59_06915 11086b48def1656cfa50e3747137a4e4 436 Gene3D G3DSA:1.10.230.10 272 384 4.6E-142 T 14-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain LH59_06915 11086b48def1656cfa50e3747137a4e4 436 Gene3D G3DSA:2.20.28.60 1 54 6.5E-26 T 14-10-2018 LH59_06915 11086b48def1656cfa50e3747137a4e4 436 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 18 430 2.3E-234 T 14-10-2018 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 LH59_06915 11086b48def1656cfa50e3747137a4e4 436 PRINTS PR00143 Citrate synthase signature 387 401 2.6E-54 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 LH59_06915 11086b48def1656cfa50e3747137a4e4 436 PRINTS PR00143 Citrate synthase signature 367 383 2.6E-54 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 LH59_06915 11086b48def1656cfa50e3747137a4e4 436 PRINTS PR00143 Citrate synthase signature 169 182 2.6E-54 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 LH59_06915 11086b48def1656cfa50e3747137a4e4 436 PRINTS PR00143 Citrate synthase signature 223 238 2.6E-54 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 LH59_06915 11086b48def1656cfa50e3747137a4e4 436 PRINTS PR00143 Citrate synthase signature 245 273 2.6E-54 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 LH59_06915 11086b48def1656cfa50e3747137a4e4 436 PRINTS PR00143 Citrate synthase signature 303 323 2.6E-54 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 LH59_06915 11086b48def1656cfa50e3747137a4e4 436 Pfam PF00285 Citrate synthase, C-terminal domain 50 419 4.6E-129 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 LH59_06915 11086b48def1656cfa50e3747137a4e4 436 PIRSF PIRSF001369 41 436 1.3E-161 T 14-10-2018 IPR024176 Citrate synthase, bacterial-type LH59_06915 11086b48def1656cfa50e3747137a4e4 436 Gene3D G3DSA:1.10.580.10 61 419 4.6E-142 T 14-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 LH59_06915 11086b48def1656cfa50e3747137a4e4 436 ProSitePatterns PS00480 Citrate synthase signature. 310 322 - T 14-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 LH59_07980 a8daeda4e6a5187be9ba0ec6b5cd3183 765 Gene3D G3DSA:3.20.20.210 6 530 0.0 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 LH59_07980 a8daeda4e6a5187be9ba0ec6b5cd3183 765 SUPERFAMILY SSF51726 414 763 1.44E-116 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 LH59_07980 a8daeda4e6a5187be9ba0ec6b5cd3183 765 SUPERFAMILY SSF51726 5 401 3.4E-110 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 LH59_07980 a8daeda4e6a5187be9ba0ec6b5cd3183 765 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 4 321 1.8E-119 T 14-10-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 LH59_07980 a8daeda4e6a5187be9ba0ec6b5cd3183 765 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 7 763 0.0 T 14-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 LH59_07980 a8daeda4e6a5187be9ba0ec6b5cd3183 765 Gene3D G3DSA:3.20.20.210 396 762 0.0 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 LH59_07980 a8daeda4e6a5187be9ba0ec6b5cd3183 765 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 437 759 1.1E-156 T 14-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 LH59_07980 a8daeda4e6a5187be9ba0ec6b5cd3183 765 PIRSF PIRSF000382 1 765 0.0 T 14-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 LH59_07980 a8daeda4e6a5187be9ba0ec6b5cd3183 765 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 2 764 37.714 T 14-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 LH59_24060 0f7d8a39d79fa0874d926db68657d44d 580 ProSitePatterns PS00211 ABC transporters family signature. 480 494 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_24060 0f7d8a39d79fa0874d926db68657d44d 580 Gene3D G3DSA:1.20.1560.10 3 326 1.3E-32 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 LH59_24060 0f7d8a39d79fa0874d926db68657d44d 580 SUPERFAMILY SSF52540 340 578 3.02E-83 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_24060 0f7d8a39d79fa0874d926db68657d44d 580 Pfam PF00005 ABC transporter 359 508 2.0E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_24060 0f7d8a39d79fa0874d926db68657d44d 580 Gene3D G3DSA:3.40.50.300 339 580 1.7E-83 T 14-10-2018 LH59_24060 0f7d8a39d79fa0874d926db68657d44d 580 Pfam PF00664 ABC transporter transmembrane region 62 292 1.0E-6 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 LH59_24060 0f7d8a39d79fa0874d926db68657d44d 580 SMART SM00382 368 554 1.9E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_24060 0f7d8a39d79fa0874d926db68657d44d 580 SUPERFAMILY SSF90123 10 328 1.26E-40 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 LH59_07650 279e6b4e3271b5f732c95dd2efa3db08 607 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 6 134 1.6E-23 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 LH59_07650 279e6b4e3271b5f732c95dd2efa3db08 607 Gene3D G3DSA:3.30.70.240 390 483 1.7E-133 T 14-10-2018 LH59_07650 279e6b4e3271b5f732c95dd2efa3db08 607 Pfam PF00679 Elongation factor G C-terminus 397 478 4.2E-22 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like LH59_07650 279e6b4e3271b5f732c95dd2efa3db08 607 SUPERFAMILY SSF50447 151 299 7.57E-29 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily LH59_07650 279e6b4e3271b5f732c95dd2efa3db08 607 Gene3D G3DSA:2.40.30.10 199 300 3.2E-27 T 14-10-2018 LH59_07650 279e6b4e3271b5f732c95dd2efa3db08 607 Gene3D G3DSA:3.40.50.300 2 197 1.3E-63 T 14-10-2018 LH59_07650 279e6b4e3271b5f732c95dd2efa3db08 607 SUPERFAMILY SSF52540 4 207 1.89E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_07650 279e6b4e3271b5f732c95dd2efa3db08 607 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 5 600 7.6E-286 T 14-10-2018 IPR006298 GTP-binding protein TypA GO:0005525 LH59_07650 279e6b4e3271b5f732c95dd2efa3db08 607 Pfam PF00009 Elongation factor Tu GTP binding domain 5 195 4.7E-54 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_07650 279e6b4e3271b5f732c95dd2efa3db08 607 Gene3D G3DSA:2.40.50.250 484 600 1.7E-133 T 14-10-2018 LH59_07650 279e6b4e3271b5f732c95dd2efa3db08 607 Pfam PF03144 Elongation factor Tu domain 2 219 290 1.3E-9 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 LH59_07650 279e6b4e3271b5f732c95dd2efa3db08 607 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 44 59 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site LH59_07650 279e6b4e3271b5f732c95dd2efa3db08 607 SUPERFAMILY SSF54980 399 514 5.28E-28 T 14-10-2018 IPR035647 EF-G domain III/V-like LH59_07650 279e6b4e3271b5f732c95dd2efa3db08 607 SUPERFAMILY SSF54980 303 388 2.66E-13 T 14-10-2018 IPR035647 EF-G domain III/V-like LH59_07650 279e6b4e3271b5f732c95dd2efa3db08 607 PRINTS PR00315 GTP-binding elongation factor signature 123 132 8.2E-15 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_07650 279e6b4e3271b5f732c95dd2efa3db08 607 PRINTS PR00315 GTP-binding elongation factor signature 7 20 8.2E-15 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_07650 279e6b4e3271b5f732c95dd2efa3db08 607 PRINTS PR00315 GTP-binding elongation factor signature 87 98 8.2E-15 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_07650 279e6b4e3271b5f732c95dd2efa3db08 607 PRINTS PR00315 GTP-binding elongation factor signature 71 81 8.2E-15 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_07650 279e6b4e3271b5f732c95dd2efa3db08 607 PRINTS PR00315 GTP-binding elongation factor signature 51 59 8.2E-15 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_07650 279e6b4e3271b5f732c95dd2efa3db08 607 Gene3D G3DSA:3.30.70.870 307 591 1.7E-133 T 14-10-2018 LH59_12650 85a10f5dde005a3b26a67f755653c3da 306 SUPERFAMILY SSF46626 156 262 2.87E-20 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_12650 85a10f5dde005a3b26a67f755653c3da 306 Gene3D G3DSA:1.10.760.10 160 274 3.0E-40 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_12650 85a10f5dde005a3b26a67f755653c3da 306 SUPERFAMILY SSF46626 43 150 2.64E-29 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_12650 85a10f5dde005a3b26a67f755653c3da 306 Gene3D G3DSA:1.10.760.10 27 157 1.6E-39 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_12650 85a10f5dde005a3b26a67f755653c3da 306 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 170 250 1.6E-9 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_08445 db71c4e1864dc5d55bc79b8ae480948e 556 SUPERFAMILY SSF51395 21 500 1.1E-139 T 14-10-2018 LH59_08445 db71c4e1864dc5d55bc79b8ae480948e 556 Gene3D G3DSA:3.20.20.70 150 501 2.3E-109 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_08445 db71c4e1864dc5d55bc79b8ae480948e 556 PIRSF PIRSF500060 11 531 1.4E-242 T 14-10-2018 IPR027283 Glutamate synthase large subunit-like protein, bacteria LH59_08445 db71c4e1864dc5d55bc79b8ae480948e 556 Pfam PF01645 Conserved region in glutamate synthase 157 474 3.9E-83 T 14-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 LH59_08445 db71c4e1864dc5d55bc79b8ae480948e 556 PIRSF PIRSF006429 6 540 1.6E-161 T 14-10-2018 IPR024188 Glutamate synthase large subunit-like protein LH59_07815 37a6aa8a4b6745f02c3d8ef2c4e71aea 107 Hamap MF_00720 Primosomal replication protein N [priB]. 1 96 22.668 T 14-10-2018 IPR023646 Primosomal replication protein PriB GO:0003697|GO:0006260|GO:0030894 LH59_07815 37a6aa8a4b6745f02c3d8ef2c4e71aea 107 Gene3D G3DSA:2.40.50.140 1 107 3.8E-37 T 14-10-2018 LH59_07815 37a6aa8a4b6745f02c3d8ef2c4e71aea 107 SUPERFAMILY SSF50249 1 97 2.06E-15 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_07815 37a6aa8a4b6745f02c3d8ef2c4e71aea 107 PIRSF PIRSF003135 1 97 2.3E-13 T 14-10-2018 IPR023646 Primosomal replication protein PriB GO:0003697|GO:0006260|GO:0030894 LH59_07815 37a6aa8a4b6745f02c3d8ef2c4e71aea 107 TIGRFAM TIGR04418 PriB_gamma: primosomal replication protein PriB 2 95 7.3E-30 T 14-10-2018 IPR023646 Primosomal replication protein PriB GO:0003697|GO:0006260|GO:0030894 LH59_02215 f86252a305ceeb959f4e5bff31c035cc 164 Pfam PF02566 OsmC-like protein 63 158 6.2E-17 T 14-10-2018 IPR003718 OsmC/Ohr family LH59_02215 f86252a305ceeb959f4e5bff31c035cc 164 Gene3D G3DSA:2.20.25.10 20 68 7.4E-8 T 14-10-2018 LH59_02215 f86252a305ceeb959f4e5bff31c035cc 164 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 35 160 2.4E-36 T 14-10-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 LH59_02215 f86252a305ceeb959f4e5bff31c035cc 164 Gene3D G3DSA:3.30.300.20 69 162 1.6E-24 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta LH59_02215 f86252a305ceeb959f4e5bff31c035cc 164 SUPERFAMILY SSF82784 16 159 4.45E-32 T 14-10-2018 IPR036102 OsmC/Ohr superfamily LH59_02325 ddc3568c08279218dc28a53e579b45d5 302 SUPERFAMILY SSF53474 8 281 2.52E-36 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_02325 ddc3568c08279218dc28a53e579b45d5 302 Pfam PF12146 Serine aminopeptidase, S33 37 264 6.4E-59 T 14-10-2018 IPR022742 Serine aminopeptidase, S33 LH59_02325 ddc3568c08279218dc28a53e579b45d5 302 Gene3D G3DSA:3.40.50.1820 6 284 3.0E-54 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_12245 ff4b8bf059a51a9787cd40575d62cc19 114 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 5 109 1.4E-27 T 14-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like LH59_22710 d26e0851fd57b3c668a3eae9f5a5a3b0 167 Pfam PF01613 Flavin reductase like domain 17 158 7.4E-31 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 LH59_22710 d26e0851fd57b3c668a3eae9f5a5a3b0 167 SMART SM00903 16 160 1.4E-49 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 LH59_22710 d26e0851fd57b3c668a3eae9f5a5a3b0 167 SUPERFAMILY SSF50475 8 158 5.4E-44 T 14-10-2018 LH59_22710 d26e0851fd57b3c668a3eae9f5a5a3b0 167 Gene3D G3DSA:2.30.110.10 2 164 2.1E-48 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 LH59_21860 1d11e4e9183d819dcd217be9a9fe93f5 976 Pfam PF04851 Type III restriction enzyme, res subunit 24 188 2.7E-16 T 14-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 LH59_21860 1d11e4e9183d819dcd217be9a9fe93f5 976 Gene3D G3DSA:3.40.50.300 235 386 2.2E-14 T 14-10-2018 LH59_21860 1d11e4e9183d819dcd217be9a9fe93f5 976 SMART SM00487 20 220 3.0E-8 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain LH59_21860 1d11e4e9183d819dcd217be9a9fe93f5 976 SUPERFAMILY SSF52540 46 359 1.22E-28 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_21860 1d11e4e9183d819dcd217be9a9fe93f5 976 Gene3D G3DSA:3.40.50.300 15 203 1.1E-20 T 14-10-2018 LH59_21860 1d11e4e9183d819dcd217be9a9fe93f5 976 Pfam PF00271 Helicase conserved C-terminal domain 278 348 3.2E-4 T 14-10-2018 IPR001650 Helicase, C-terminal LH59_07230 176a6f70b0fe898b85923147296d8f18 386 Gene3D G3DSA:3.40.50.2000 1 191 8.7E-72 T 14-10-2018 LH59_07230 176a6f70b0fe898b85923147296d8f18 386 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 1 367 2.0E-140 T 14-10-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 LH59_07230 176a6f70b0fe898b85923147296d8f18 386 Gene3D G3DSA:3.40.50.2000 192 354 9.9E-66 T 14-10-2018 LH59_07230 176a6f70b0fe898b85923147296d8f18 386 SUPERFAMILY SSF53756 1 369 2.47E-128 T 14-10-2018 LH59_07230 176a6f70b0fe898b85923147296d8f18 386 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 22 367 2.7E-117 T 14-10-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 LH59_01815 1dfa52033523c8138aacf43480f7d220 262 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 3 262 35.48 T 14-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 LH59_01815 1dfa52033523c8138aacf43480f7d220 262 Gene3D G3DSA:3.20.20.70 1 262 2.6E-103 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_01815 1dfa52033523c8138aacf43480f7d220 262 Pfam PF00218 Indole-3-glycerol phosphate synthase 5 259 3.7E-94 T 14-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 LH59_01815 1dfa52033523c8138aacf43480f7d220 262 SUPERFAMILY SSF51366 1 261 3.88E-88 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 LH59_01815 1dfa52033523c8138aacf43480f7d220 262 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 56 74 - T 14-10-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 LH59_27415 d42cf9fcb004bf8fc93c024056cccb2f 458 Pfam PF13692 Glycosyl transferases group 1 243 382 2.8E-10 T 14-10-2018 LH59_27415 d42cf9fcb004bf8fc93c024056cccb2f 458 SUPERFAMILY SSF53756 34 416 4.19E-32 T 14-10-2018 LH59_27415 d42cf9fcb004bf8fc93c024056cccb2f 458 Gene3D G3DSA:3.40.50.2000 217 397 8.1E-24 T 14-10-2018 LH59_27415 d42cf9fcb004bf8fc93c024056cccb2f 458 Gene3D G3DSA:3.40.50.2000 131 216 8.1E-24 T 14-10-2018 LH59_01600 a97581232b477c5671e7989389f8e5fd 562 PIRSF PIRSF002741 25 562 1.3E-137 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 LH59_01600 a97581232b477c5671e7989389f8e5fd 562 Gene3D G3DSA:3.40.190.10 41 306 1.1E-73 T 14-10-2018 LH59_01600 a97581232b477c5671e7989389f8e5fd 562 SUPERFAMILY SSF53850 60 559 1.99E-130 T 14-10-2018 LH59_01600 a97581232b477c5671e7989389f8e5fd 562 Gene3D G3DSA:3.10.105.10 309 530 1.7E-53 T 14-10-2018 LH59_01600 a97581232b477c5671e7989389f8e5fd 562 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 106 462 1.3E-89 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain LH59_12215 8aa9c30409af0dc0d7862679ebd6b15e 375 Pfam PF00149 Calcineurin-like phosphoesterase 3 104 9.6E-12 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 LH59_12215 8aa9c30409af0dc0d7862679ebd6b15e 375 SUPERFAMILY SSF56300 4 292 7.74E-38 T 14-10-2018 LH59_12215 8aa9c30409af0dc0d7862679ebd6b15e 375 PIRSF PIRSF033093 1 371 1.1E-112 T 14-10-2018 IPR014577 Uncharacterised conserved protein UCP033093, metallophosphoesterase-type LH59_12215 8aa9c30409af0dc0d7862679ebd6b15e 375 Gene3D G3DSA:3.60.21.10 1 246 3.7E-30 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like LH59_12415 3e56d317c5a10e46875c91eeefb8bd64 242 ProSitePatterns PS00195 Glutaredoxin active site. 175 191 - T 14-10-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 LH59_12415 3e56d317c5a10e46875c91eeefb8bd64 242 Gene3D G3DSA:3.40.30.10 171 242 2.9E-18 T 14-10-2018 LH59_12415 3e56d317c5a10e46875c91eeefb8bd64 242 Pfam PF00462 Glutaredoxin 173 231 1.7E-13 T 14-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 LH59_12415 3e56d317c5a10e46875c91eeefb8bd64 242 Gene3D G3DSA:3.40.30.10 4 165 2.1E-63 T 14-10-2018 LH59_12415 3e56d317c5a10e46875c91eeefb8bd64 242 PRINTS PR00160 Glutaredoxin signature 214 227 1.0E-11 T 14-10-2018 IPR014025 Glutaredoxin subgroup LH59_12415 3e56d317c5a10e46875c91eeefb8bd64 242 PRINTS PR00160 Glutaredoxin signature 173 191 1.0E-11 T 14-10-2018 IPR014025 Glutaredoxin subgroup LH59_12415 3e56d317c5a10e46875c91eeefb8bd64 242 PRINTS PR00160 Glutaredoxin signature 228 241 1.0E-11 T 14-10-2018 IPR014025 Glutaredoxin subgroup LH59_12415 3e56d317c5a10e46875c91eeefb8bd64 242 SUPERFAMILY SSF52833 5 239 6.88E-45 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_12415 3e56d317c5a10e46875c91eeefb8bd64 242 Pfam PF08534 Redoxin 6 160 2.3E-33 T 14-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 LH59_12415 3e56d317c5a10e46875c91eeefb8bd64 242 TIGRFAM TIGR02190 GlrX-dom: glutaredoxin-family domain 164 242 3.4E-37 T 14-10-2018 IPR011906 Glutaredoxin domain KEGG: 00480+1.11.1.15 LH59_22180 429995f8bcd04ec009a4dd60625b0753 327 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 10 327 57.148 T 14-10-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 LH59_22180 429995f8bcd04ec009a4dd60625b0753 327 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 12 327 55.941 T 14-10-2018 IPR023009 Tyrosine recombinase XerC/XerD LH59_22180 429995f8bcd04ec009a4dd60625b0753 327 SUPERFAMILY SSF47823 11 129 1.29E-24 T 14-10-2018 LH59_22180 429995f8bcd04ec009a4dd60625b0753 327 Gene3D G3DSA:1.10.443.10 139 321 1.1E-68 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 LH59_22180 429995f8bcd04ec009a4dd60625b0753 327 Pfam PF00589 Phage integrase family 141 312 1.0E-49 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 LH59_22180 429995f8bcd04ec009a4dd60625b0753 327 Gene3D G3DSA:1.10.150.130 10 127 4.9E-18 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal LH59_22180 429995f8bcd04ec009a4dd60625b0753 327 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 14 48 4.3E-6 T 14-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 LH59_22180 429995f8bcd04ec009a4dd60625b0753 327 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 73 119 2.4E-7 T 14-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 LH59_22180 429995f8bcd04ec009a4dd60625b0753 327 SUPERFAMILY SSF56349 135 324 2.15E-57 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 LH59_22180 429995f8bcd04ec009a4dd60625b0753 327 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 76 326 2.8E-102 T 14-10-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 LH59_24835 2887cda6b46cdc59bd5429f7c6f8fa59 204 SUPERFAMILY SSF54719 89 202 2.23E-42 T 14-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 LH59_24835 2887cda6b46cdc59bd5429f7c6f8fa59 204 PIRSF PIRSF000349 1 204 2.0E-78 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 LH59_24835 2887cda6b46cdc59bd5429f7c6f8fa59 204 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 97 198 3.5E-36 T 14-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 LH59_24835 2887cda6b46cdc59bd5429f7c6f8fa59 204 PRINTS PR01703 Manganese superoxide dismutase signature 163 175 1.8E-28 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 LH59_24835 2887cda6b46cdc59bd5429f7c6f8fa59 204 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 1.8E-28 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 LH59_24835 2887cda6b46cdc59bd5429f7c6f8fa59 204 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 1.8E-28 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 LH59_24835 2887cda6b46cdc59bd5429f7c6f8fa59 204 PRINTS PR01703 Manganese superoxide dismutase signature 73 86 1.8E-28 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 LH59_24835 2887cda6b46cdc59bd5429f7c6f8fa59 204 PRINTS PR01703 Manganese superoxide dismutase signature 126 134 1.8E-28 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 LH59_24835 2887cda6b46cdc59bd5429f7c6f8fa59 204 SUPERFAMILY SSF46609 2 91 1.44E-36 T 14-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 LH59_24835 2887cda6b46cdc59bd5429f7c6f8fa59 204 Gene3D G3DSA:1.10.287.990 20 90 1.4E-29 T 14-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 LH59_24835 2887cda6b46cdc59bd5429f7c6f8fa59 204 Gene3D G3DSA:2.40.500.20 91 204 3.7E-43 T 14-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 LH59_24835 2887cda6b46cdc59bd5429f7c6f8fa59 204 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 165 172 - T 14-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 LH59_24835 2887cda6b46cdc59bd5429f7c6f8fa59 204 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 2 90 2.4E-32 T 14-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 LH59_09120 0c77f915bf0b5743b9048d73797cc210 225 SUPERFAMILY SSF51182 76 211 2.25E-21 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_09120 0c77f915bf0b5743b9048d73797cc210 225 Pfam PF07883 Cupin domain 140 209 1.9E-11 T 14-10-2018 IPR013096 Cupin 2, conserved barrel LH59_09120 0c77f915bf0b5743b9048d73797cc210 225 Gene3D G3DSA:1.10.260.40 30 98 2.9E-17 T 14-10-2018 LH59_09120 0c77f915bf0b5743b9048d73797cc210 225 SUPERFAMILY SSF47413 30 96 8.16E-17 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 LH59_09120 0c77f915bf0b5743b9048d73797cc210 225 Pfam PF13560 Helix-turn-helix domain 33 89 2.7E-13 T 14-10-2018 LH59_09120 0c77f915bf0b5743b9048d73797cc210 225 Gene3D G3DSA:2.60.120.10 106 209 1.1E-14 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_09120 0c77f915bf0b5743b9048d73797cc210 225 SMART SM00530 36 91 1.8E-12 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LH59_13270 7f4821649006645009c35dc50ea0ee05 303 Pfam PF00034 Cytochrome c 125 200 1.4E-6 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_13270 7f4821649006645009c35dc50ea0ee05 303 SUPERFAMILY SSF46626 116 202 1.09E-20 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_13270 7f4821649006645009c35dc50ea0ee05 303 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 233 298 2.0E-6 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_13270 7f4821649006645009c35dc50ea0ee05 303 SUPERFAMILY SSF46626 232 301 9.77E-17 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_13270 7f4821649006645009c35dc50ea0ee05 303 Gene3D G3DSA:1.10.760.10 222 303 4.1E-21 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_13270 7f4821649006645009c35dc50ea0ee05 303 Gene3D G3DSA:1.10.760.10 118 203 1.0E-24 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_12405 d8fa5acc4e09a334f6df67f451fc70a3 757 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 639 655 7.0E-6 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 LH59_12405 d8fa5acc4e09a334f6df67f451fc70a3 757 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 670 695 7.0E-6 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 LH59_12405 d8fa5acc4e09a334f6df67f451fc70a3 757 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 210 717 3.6E-93 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 LH59_12405 d8fa5acc4e09a334f6df67f451fc70a3 757 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 171 748 8.4E-189 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 LH59_12405 d8fa5acc4e09a334f6df67f451fc70a3 757 Gene3D G3DSA:3.40.1110.10 451 571 3.7E-94 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 LH59_12405 d8fa5acc4e09a334f6df67f451fc70a3 757 SUPERFAMILY SSF55008 5 78 2.23E-23 T 14-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 LH59_12405 d8fa5acc4e09a334f6df67f451fc70a3 757 Gene3D G3DSA:3.30.70.100 8 85 3.5E-24 T 14-10-2018 LH59_12405 d8fa5acc4e09a334f6df67f451fc70a3 757 ProSitePatterns PS01047 Heavy-metal-associated domain. 14 43 - T 14-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 LH59_12405 d8fa5acc4e09a334f6df67f451fc70a3 757 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 442 448 - T 14-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 LH59_12405 d8fa5acc4e09a334f6df67f451fc70a3 757 SUPERFAMILY SSF56784 438 746 1.54E-60 T 14-10-2018 IPR036412 HAD-like superfamily LH59_12405 d8fa5acc4e09a334f6df67f451fc70a3 757 Pfam PF00122 E1-E2 ATPase 239 419 2.2E-61 T 14-10-2018 LH59_12405 d8fa5acc4e09a334f6df67f451fc70a3 757 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 153 749 1.9E-178 T 14-10-2018 LH59_12405 d8fa5acc4e09a334f6df67f451fc70a3 757 Gene3D G3DSA:2.70.150.20 231 343 1.6E-42 T 14-10-2018 LH59_12405 d8fa5acc4e09a334f6df67f451fc70a3 757 SUPERFAMILY SSF81665 189 728 9.42E-14 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 LH59_12405 d8fa5acc4e09a334f6df67f451fc70a3 757 Gene3D G3DSA:3.40.50.1000 421 691 3.7E-94 T 14-10-2018 IPR023214 HAD superfamily LH59_12405 d8fa5acc4e09a334f6df67f451fc70a3 757 Pfam PF00403 Heavy-metal-associated domain 12 72 3.3E-16 T 14-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 LH59_12405 d8fa5acc4e09a334f6df67f451fc70a3 757 SUPERFAMILY SSF81653 240 338 2.62E-32 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 LH59_12405 d8fa5acc4e09a334f6df67f451fc70a3 757 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 639 658 2.1E-28 T 14-10-2018 LH59_12405 d8fa5acc4e09a334f6df67f451fc70a3 757 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 288 302 2.1E-28 T 14-10-2018 LH59_12405 d8fa5acc4e09a334f6df67f451fc70a3 757 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 440 454 2.1E-28 T 14-10-2018 LH59_12405 d8fa5acc4e09a334f6df67f451fc70a3 757 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 662 674 2.1E-28 T 14-10-2018 LH59_12405 d8fa5acc4e09a334f6df67f451fc70a3 757 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 564 575 2.1E-28 T 14-10-2018 LH59_12405 d8fa5acc4e09a334f6df67f451fc70a3 757 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 586 596 2.1E-28 T 14-10-2018 LH59_12405 d8fa5acc4e09a334f6df67f451fc70a3 757 Pfam PF00702 haloacid dehalogenase-like hydrolase 437 653 1.1E-46 T 14-10-2018 LH59_07460 1d294d75d0ed69d04a1ea20aabcec3a7 416 Gene3D G3DSA:3.30.2010.10 201 282 1.6E-30 T 14-10-2018 LH59_07460 1d294d75d0ed69d04a1ea20aabcec3a7 416 Pfam PF01435 Peptidase family M48 206 413 1.8E-37 T 14-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 LH59_07460 1d294d75d0ed69d04a1ea20aabcec3a7 416 Pfam PF16491 CAAX prenyl protease N-terminal, five membrane helices 24 202 3.1E-57 T 14-10-2018 IPR032456 CAAX prenyl protease 1, N-terminal KEGG: 00900+3.4.24.84 LH59_20440 1e06e034a4bbd69f3ed8ef5734994717 432 Pfam PF09375 Imelysin 36 404 1.1E-102 T 14-10-2018 IPR018976 Imelysin-like domain LH59_20440 1e06e034a4bbd69f3ed8ef5734994717 432 Gene3D G3DSA:1.20.1420.20 16 409 1.2E-87 T 14-10-2018 IPR038352 Imelysin-like domain superfamily LH59_07365 34371d0aa80905dbb4d1938f1bc07c9f 309 Pfam PF01012 Electron transfer flavoprotein domain 3 169 2.7E-40 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 LH59_07365 34371d0aa80905dbb4d1938f1bc07c9f 309 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 253 279 - T 14-10-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 LH59_07365 34371d0aa80905dbb4d1938f1bc07c9f 309 Gene3D G3DSA:3.40.50.620 3 183 1.3E-56 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LH59_07365 34371d0aa80905dbb4d1938f1bc07c9f 309 Gene3D G3DSA:3.40.50.1220 184 309 5.8E-58 T 14-10-2018 LH59_07365 34371d0aa80905dbb4d1938f1bc07c9f 309 SUPERFAMILY SSF52402 3 186 4.88E-58 T 14-10-2018 LH59_07365 34371d0aa80905dbb4d1938f1bc07c9f 309 SMART SM00893 3 182 5.6E-58 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 LH59_07365 34371d0aa80905dbb4d1938f1bc07c9f 309 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 190 272 3.3E-36 T 14-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 LH59_07365 34371d0aa80905dbb4d1938f1bc07c9f 309 SUPERFAMILY SSF52467 187 309 1.64E-48 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily LH59_07365 34371d0aa80905dbb4d1938f1bc07c9f 309 PIRSF PIRSF000089 1 309 3.9E-108 T 14-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 LH59_26960 8e5e069ac2d91adb744565877927482a 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 4.6E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_26960 8e5e069ac2d91adb744565877927482a 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 4.6E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_26960 8e5e069ac2d91adb744565877927482a 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 4.6E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_26960 8e5e069ac2d91adb744565877927482a 261 Gene3D G3DSA:3.40.50.720 1 261 5.3E-79 T 14-10-2018 LH59_26960 8e5e069ac2d91adb744565877927482a 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.1E-28 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_26960 8e5e069ac2d91adb744565877927482a 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 1.1E-28 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_26960 8e5e069ac2d91adb744565877927482a 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.1E-28 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_26960 8e5e069ac2d91adb744565877927482a 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.1E-28 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_26960 8e5e069ac2d91adb744565877927482a 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.1E-28 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_26960 8e5e069ac2d91adb744565877927482a 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.1E-28 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_26960 8e5e069ac2d91adb744565877927482a 261 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 7 261 3.7E-103 T 14-10-2018 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 LH59_26960 8e5e069ac2d91adb744565877927482a 261 Pfam PF00106 short chain dehydrogenase 7 199 3.5E-53 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_26960 8e5e069ac2d91adb744565877927482a 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LH59_26960 8e5e069ac2d91adb744565877927482a 261 SUPERFAMILY SSF51735 5 260 1.31E-71 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_11510 00024b3bbb0bdf9a305d26366edece95 149 PIRSF PIRSF019404 1 148 6.6E-49 T 14-10-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 LH59_11510 00024b3bbb0bdf9a305d26366edece95 149 PRINTS PR01004 Flagellar FliJ protein signature 108 126 5.4E-14 T 14-10-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 LH59_11510 00024b3bbb0bdf9a305d26366edece95 149 PRINTS PR01004 Flagellar FliJ protein signature 44 61 5.4E-14 T 14-10-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 LH59_11510 00024b3bbb0bdf9a305d26366edece95 149 PRINTS PR01004 Flagellar FliJ protein signature 63 84 5.4E-14 T 14-10-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 LH59_11510 00024b3bbb0bdf9a305d26366edece95 149 PRINTS PR01004 Flagellar FliJ protein signature 4 26 5.4E-14 T 14-10-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 LH59_11510 00024b3bbb0bdf9a305d26366edece95 149 PRINTS PR01004 Flagellar FliJ protein signature 126 146 5.4E-14 T 14-10-2018 IPR018006 Flagellar FliJ, proteobacteria GO:0003774|GO:0006935|GO:0009288|GO:0016020|GO:0071973 LH59_11510 00024b3bbb0bdf9a305d26366edece95 149 TIGRFAM TIGR02473 flagell_FliJ: flagellar export protein FliJ 6 144 8.8E-31 T 14-10-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 LH59_11510 00024b3bbb0bdf9a305d26366edece95 149 Pfam PF02050 Flagellar FliJ protein 19 141 4.6E-35 T 14-10-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 LH59_00150 cdd79142d5f1842b86afff6329f788d6 277 Pfam PF06445 GyrI-like small molecule binding domain 127 277 4.4E-31 T 14-10-2018 IPR029442 GyrI-like small molecule binding domain LH59_00150 cdd79142d5f1842b86afff6329f788d6 277 SUPERFAMILY SSF55136 127 277 1.96E-35 T 14-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily LH59_00150 cdd79142d5f1842b86afff6329f788d6 277 SMART SM00871 125 277 3.2E-39 T 14-10-2018 IPR010499 Bacterial transcription activator, effector binding LH59_00150 cdd79142d5f1842b86afff6329f788d6 277 Gene3D G3DSA:3.20.80.10 126 277 9.7E-40 T 14-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily LH59_00150 cdd79142d5f1842b86afff6329f788d6 277 Gene3D G3DSA:1.10.10.60 6 65 8.8E-10 T 14-10-2018 LH59_00150 cdd79142d5f1842b86afff6329f788d6 277 SMART SM00342 27 110 4.0E-22 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_00150 cdd79142d5f1842b86afff6329f788d6 277 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 64 106 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 LH59_00150 cdd79142d5f1842b86afff6329f788d6 277 Pfam PF12833 Helix-turn-helix domain 33 111 1.1E-18 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_00150 cdd79142d5f1842b86afff6329f788d6 277 SUPERFAMILY SSF46689 11 58 2.02E-7 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_00150 cdd79142d5f1842b86afff6329f788d6 277 Gene3D G3DSA:1.10.10.60 66 118 1.2E-11 T 14-10-2018 LH59_00150 cdd79142d5f1842b86afff6329f788d6 277 SUPERFAMILY SSF46689 63 112 9.41E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_23440 ffa9257d2ec3fd11d69af8694d9d5aff 295 Pfam PF03466 LysR substrate binding domain 96 286 1.2E-28 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_23440 ffa9257d2ec3fd11d69af8694d9d5aff 295 Gene3D G3DSA:1.10.10.10 9 94 7.5E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_23440 ffa9257d2ec3fd11d69af8694d9d5aff 295 SUPERFAMILY SSF53850 97 290 9.53E-27 T 14-10-2018 LH59_23440 ffa9257d2ec3fd11d69af8694d9d5aff 295 Gene3D G3DSA:3.40.190.10 104 269 1.3E-48 T 14-10-2018 LH59_23440 ffa9257d2ec3fd11d69af8694d9d5aff 295 Gene3D G3DSA:3.40.190.10 171 264 1.3E-48 T 14-10-2018 LH59_23440 ffa9257d2ec3fd11d69af8694d9d5aff 295 SUPERFAMILY SSF46785 8 119 3.37E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_23440 ffa9257d2ec3fd11d69af8694d9d5aff 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 15 73 5.8E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_05405 2972c80d82ecb550201e816aed5019d6 251 Pfam PF09694 Bacterial protein of unknown function (Gcw_chp) 25 251 4.0E-74 T 14-10-2018 IPR010239 Conserved hypothetical protein CHP02001 LH59_05405 2972c80d82ecb550201e816aed5019d6 251 TIGRFAM TIGR02001 gcw_chp: conserved hypothetical protein 1 251 3.2E-70 T 14-10-2018 IPR010239 Conserved hypothetical protein CHP02001 LH59_13425 7d07b584eced874ec595fd5957059ede 135 Pfam PF02501 Type II secretion system (T2SS), protein I 53 130 2.0E-12 T 14-10-2018 IPR003413 Type II secretion system protein I domain GO:0008565|GO:0015627|GO:0015628 LH59_13425 7d07b584eced874ec595fd5957059ede 135 TIGRFAM TIGR01707 gspI: type II secretion system protein I 19 116 6.7E-20 T 14-10-2018 IPR010052 Type II secretion system protein I GO:0008565|GO:0015627|GO:0015628 LH59_13425 7d07b584eced874ec595fd5957059ede 135 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 18 38 - T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site LH59_13425 7d07b584eced874ec595fd5957059ede 135 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 18 40 1.8E-6 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site LH59_13425 7d07b584eced874ec595fd5957059ede 135 Pfam PF07963 Prokaryotic N-terminal methylation motif 16 40 7.4E-7 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site LH59_13425 7d07b584eced874ec595fd5957059ede 135 SUPERFAMILY SSF54523 51 130 6.28E-10 T 14-10-2018 LH59_12630 1c414c9938cead89826471e5ef2ede78 764 Gene3D G3DSA:3.10.20.30 433 507 1.8E-32 T 14-10-2018 IPR012675 Beta-grasp domain superfamily LH59_12630 1c414c9938cead89826471e5ef2ede78 764 SUPERFAMILY SSF81271 427 500 3.05E-23 T 14-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 LH59_12630 1c414c9938cead89826471e5ef2ede78 764 Pfam PF13328 HD domain 78 227 3.7E-51 T 14-10-2018 IPR003607 HD/PDEase domain LH59_12630 1c414c9938cead89826471e5ef2ede78 764 Pfam PF04607 Region found in RelA / SpoT proteins 287 395 8.2E-30 T 14-10-2018 IPR007685 RelA/SpoT GO:0015969 LH59_12630 1c414c9938cead89826471e5ef2ede78 764 SMART SM00954 287 397 2.4E-57 T 14-10-2018 IPR007685 RelA/SpoT GO:0015969 LH59_12630 1c414c9938cead89826471e5ef2ede78 764 Gene3D G3DSA:3.30.460.10 245 377 9.8E-42 T 14-10-2018 LH59_12630 1c414c9938cead89826471e5ef2ede78 764 Gene3D G3DSA:3.30.70.260 688 764 1.8E-9 T 14-10-2018 LH59_12630 1c414c9938cead89826471e5ef2ede78 764 SUPERFAMILY SSF55021 691 758 7.63E-5 T 14-10-2018 LH59_12630 1c414c9938cead89826471e5ef2ede78 764 SUPERFAMILY SSF109604 59 241 1.02E-70 T 14-10-2018 LH59_12630 1c414c9938cead89826471e5ef2ede78 764 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 78 759 1.1E-219 T 14-10-2018 IPR004811 RelA/SpoT family GO:0015969 LH59_12630 1c414c9938cead89826471e5ef2ede78 764 Pfam PF02824 TGS domain 440 499 7.0E-24 T 14-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 LH59_12630 1c414c9938cead89826471e5ef2ede78 764 Pfam PF13291 ACT domain 688 761 1.2E-15 T 14-10-2018 IPR002912 ACT domain LH59_12630 1c414c9938cead89826471e5ef2ede78 764 SMART SM00471 93 205 2.9E-8 T 14-10-2018 IPR003607 HD/PDEase domain LH59_12630 1c414c9938cead89826471e5ef2ede78 764 SUPERFAMILY SSF81301 233 444 3.27E-59 T 14-10-2018 LH59_12630 1c414c9938cead89826471e5ef2ede78 764 Gene3D G3DSA:1.10.3210.10 53 242 2.2E-77 T 14-10-2018 LH59_08110 ade767e98a16b5ccb0c08aea52d59974 153 Gene3D G3DSA:3.40.1230.10 1 149 3.4E-43 T 14-10-2018 IPR036748 MTH938-like superfamily LH59_08110 ade767e98a16b5ccb0c08aea52d59974 153 SUPERFAMILY SSF64076 13 147 8.9E-31 T 14-10-2018 IPR036748 MTH938-like superfamily LH59_08110 ade767e98a16b5ccb0c08aea52d59974 153 Pfam PF04430 Protein of unknown function (DUF498/DUF598) 15 145 3.8E-32 T 14-10-2018 IPR007523 NDUFAF3/Mth938 domain-containing protein LH59_27575 5d75b4fe74164a2dbae0d07d68d6fcce 724 TIGRFAM TIGR01345 malate_syn_G: malate synthase G 4 722 0.0 T 14-10-2018 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 LH59_27575 5d75b4fe74164a2dbae0d07d68d6fcce 724 Gene3D G3DSA:1.20.1220.12 583 724 2.5E-72 T 14-10-2018 LH59_27575 5d75b4fe74164a2dbae0d07d68d6fcce 724 SUPERFAMILY SSF51645 4 721 1.31E-304 T 14-10-2018 IPR011076 Malate synthase-like superfamily GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 LH59_27575 5d75b4fe74164a2dbae0d07d68d6fcce 724 Gene3D G3DSA:3.20.20.360 10 570 2.3E-281 T 14-10-2018 LH59_27575 5d75b4fe74164a2dbae0d07d68d6fcce 724 Pfam PF01274 Malate synthase 18 696 1.3E-176 T 14-10-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 LH59_27575 5d75b4fe74164a2dbae0d07d68d6fcce 724 Gene3D G3DSA:2.170.170.11 135 262 2.3E-281 T 14-10-2018 IPR023310 Malate synthase G, beta sub-domain GO:0004474 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 LH59_27575 5d75b4fe74164a2dbae0d07d68d6fcce 724 Hamap MF_00641 Malate synthase G [glcB]. 1 724 406.345 T 14-10-2018 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 LH59_20105 585c2de892e237606d5746848760fae1 617 Gene3D G3DSA:1.20.1560.10 31 357 2.8E-25 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 LH59_20105 585c2de892e237606d5746848760fae1 617 Pfam PF00664 ABC transporter transmembrane region 49 309 8.2E-10 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 LH59_20105 585c2de892e237606d5746848760fae1 617 SUPERFAMILY SSF90123 36 350 1.19E-46 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 LH59_20105 585c2de892e237606d5746848760fae1 617 SUPERFAMILY SSF52540 358 609 1.52E-85 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_20105 585c2de892e237606d5746848760fae1 617 Gene3D G3DSA:3.40.50.300 359 612 3.4E-89 T 14-10-2018 LH59_20105 585c2de892e237606d5746848760fae1 617 ProSitePatterns PS00211 ABC transporters family signature. 511 525 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_20105 585c2de892e237606d5746848760fae1 617 Pfam PF00005 ABC transporter 388 539 3.1E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_20105 585c2de892e237606d5746848760fae1 617 SMART SM00382 394 585 6.2E-20 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_05055 d95cc446acbca61d99298634f9188f29 447 SUPERFAMILY SSF53092 5 179 1.83E-47 T 14-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal LH59_05055 d95cc446acbca61d99298634f9188f29 447 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 353 365 - T 14-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site LH59_05055 d95cc446acbca61d99298634f9188f29 447 SMART SM01011 6 141 3.2E-58 T 14-10-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 LH59_05055 d95cc446acbca61d99298634f9188f29 447 Gene3D G3DSA:3.40.350.10 8 176 3.7E-48 T 14-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal LH59_05055 d95cc446acbca61d99298634f9188f29 447 Pfam PF05195 Aminopeptidase P, N-terminal domain 11 130 4.2E-34 T 14-10-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 LH59_05055 d95cc446acbca61d99298634f9188f29 447 Gene3D G3DSA:3.90.230.10 177 447 1.2E-93 T 14-10-2018 LH59_05055 d95cc446acbca61d99298634f9188f29 447 SUPERFAMILY SSF55920 180 445 2.75E-80 T 14-10-2018 IPR036005 Creatinase/aminopeptidase-like LH59_05055 d95cc446acbca61d99298634f9188f29 447 Pfam PF00557 Metallopeptidase family M24 186 424 3.1E-60 T 14-10-2018 IPR000994 Peptidase M24 LH59_23015 d62ae093e1a50558a7b755e44160e80b 150 TIGRFAM TIGR02695 azurin: azurin 24 148 1.1E-62 T 14-10-2018 IPR014068 Azurin LH59_23015 d62ae093e1a50558a7b755e44160e80b 150 SUPERFAMILY SSF49503 22 148 1.05E-47 T 14-10-2018 IPR008972 Cupredoxin LH59_23015 d62ae093e1a50558a7b755e44160e80b 150 Gene3D G3DSA:2.60.40.420 22 149 4.4E-49 T 14-10-2018 IPR008972 Cupredoxin LH59_23015 d62ae093e1a50558a7b755e44160e80b 150 ProDom PD003655 COPPER ELECTRON AZURIN METAL-BINDING PERIPLASMIC PRECURSOR SIGNAL SEQUENCING DIRECT MEMBRANE 28 146 4.0E-66 T 14-10-2018 LH59_23015 d62ae093e1a50558a7b755e44160e80b 150 Pfam PF00127 Copper binding proteins, plastocyanin/azurin family 22 148 4.6E-32 T 14-10-2018 IPR000923 Blue (type 1) copper domain GO:0005507|GO:0009055 LH59_23015 d62ae093e1a50558a7b755e44160e80b 150 ProSitePatterns PS00196 Type-1 copper (blue) proteins signature. 126 142 - T 14-10-2018 IPR028871 Blue (type 1) copper protein, binding site LH59_12810 080079836e8931d0fd2d0d88f42da91c 128 Pfam PF01042 Endoribonuclease L-PSP 9 127 5.8E-38 T 14-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 LH59_12810 080079836e8931d0fd2d0d88f42da91c 128 Gene3D G3DSA:3.30.1330.40 1 128 2.2E-46 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 LH59_12810 080079836e8931d0fd2d0d88f42da91c 128 SUPERFAMILY SSF55298 1 128 4.24E-41 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 LH59_12810 080079836e8931d0fd2d0d88f42da91c 128 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 3 127 6.7E-44 T 14-10-2018 IPR006056 RidA family Reactome: R-HSA-8849175 LH59_05515 cb727f3a81e3e37cfd4ea4ec5b73bfff 505 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 68 410 2.0E-68 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain LH59_05515 cb727f3a81e3e37cfd4ea4ec5b73bfff 505 PIRSF PIRSF002741 1 502 6.7E-65 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 LH59_05515 cb727f3a81e3e37cfd4ea4ec5b73bfff 505 Gene3D G3DSA:3.10.105.10 268 473 1.2E-26 T 14-10-2018 LH59_05515 cb727f3a81e3e37cfd4ea4ec5b73bfff 505 Gene3D G3DSA:3.40.190.10 10 263 1.5E-57 T 14-10-2018 LH59_05515 cb727f3a81e3e37cfd4ea4ec5b73bfff 505 SUPERFAMILY SSF53850 21 501 4.92E-96 T 14-10-2018 LH59_14145 d2000cc25815cd80192683ce9cb951ce 263 Gene3D G3DSA:3.40.190.10 40 258 5.8E-68 T 14-10-2018 LH59_14145 d2000cc25815cd80192683ce9cb951ce 263 SMART SM00079 36 259 0.0094 T 14-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 LH59_14145 d2000cc25815cd80192683ce9cb951ce 263 Gene3D G3DSA:3.40.190.10 124 216 5.8E-68 T 14-10-2018 LH59_14145 d2000cc25815cd80192683ce9cb951ce 263 SMART SM00062 38 260 1.2E-63 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_14145 d2000cc25815cd80192683ce9cb951ce 263 SUPERFAMILY SSF53850 2 260 2.36E-66 T 14-10-2018 LH59_14145 d2000cc25815cd80192683ce9cb951ce 263 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 39 258 1.1E-63 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_20010 aa7160d8d2320d8e7b950b9f1f9455ee 295 Gene3D G3DSA:3.90.550.10 2 286 1.2E-16 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases LH59_20010 aa7160d8d2320d8e7b950b9f1f9455ee 295 SUPERFAMILY SSF53448 3 176 1.41E-17 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases LH59_20010 aa7160d8d2320d8e7b950b9f1f9455ee 295 Pfam PF00535 Glycosyl transferase family 2 7 139 1.6E-11 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 LH59_13295 a4eb4fab404f602866dc96f677967ddc 437 SMART SM00387 322 433 3.9E-30 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_13295 a4eb4fab404f602866dc96f677967ddc 437 Gene3D G3DSA:3.30.565.10 281 430 3.2E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_13295 a4eb4fab404f602866dc96f677967ddc 437 SUPERFAMILY SSF55874 266 429 5.58E-36 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_13295 a4eb4fab404f602866dc96f677967ddc 437 PRINTS PR00344 Bacterial sensor protein C-terminal signature 376 386 5.2E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_13295 a4eb4fab404f602866dc96f677967ddc 437 PRINTS PR00344 Bacterial sensor protein C-terminal signature 358 372 5.2E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_13295 a4eb4fab404f602866dc96f677967ddc 437 PRINTS PR00344 Bacterial sensor protein C-terminal signature 393 411 5.2E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_13295 a4eb4fab404f602866dc96f677967ddc 437 Pfam PF00512 His Kinase A (phospho-acceptor) domain 213 275 1.4E-8 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_13295 a4eb4fab404f602866dc96f677967ddc 437 SMART SM00388 211 276 3.2E-10 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_13295 a4eb4fab404f602866dc96f677967ddc 437 Gene3D G3DSA:1.10.287.130 162 277 6.3E-23 T 14-10-2018 LH59_13295 a4eb4fab404f602866dc96f677967ddc 437 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 328 428 1.1E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_13295 a4eb4fab404f602866dc96f677967ddc 437 SMART SM00304 158 210 1.2E-4 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_13295 a4eb4fab404f602866dc96f677967ddc 437 SUPERFAMILY SSF47384 196 275 1.39E-13 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 LH59_06315 e85d129458c6960d507b07af659c7d27 135 Pfam PF04266 ASCH domain 23 128 2.4E-19 T 14-10-2018 IPR007374 ASCH domain LH59_06315 e85d129458c6960d507b07af659c7d27 135 SMART SM01022 13 128 1.5E-36 T 14-10-2018 IPR007374 ASCH domain LH59_06315 e85d129458c6960d507b07af659c7d27 135 SUPERFAMILY SSF88697 7 130 1.52E-37 T 14-10-2018 IPR015947 PUA-like superfamily LH59_06315 e85d129458c6960d507b07af659c7d27 135 PIRSF PIRSF021320 4 131 1.3E-36 T 14-10-2018 IPR009326 Protein of unknown function DUF984 LH59_06315 e85d129458c6960d507b07af659c7d27 135 Gene3D G3DSA:3.10.400.10 2 135 6.9E-44 T 14-10-2018 LH59_08945 169d352a64bb27e13ebf2dfa9f3fcd27 185 Pfam PF07291 Methylamine utilisation protein MauE 2 172 6.2E-15 T 14-10-2018 IPR009908 Methylamine utilisation protein, MauE GO:0016021|GO:0030416 LH59_20150 0e057442975cc466e123cf8894bc3f24 254 Gene3D G3DSA:1.10.10.10 3 74 3.0E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_20150 0e057442975cc466e123cf8894bc3f24 254 Pfam PF09339 IclR helix-turn-helix domain 5 55 6.3E-11 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_20150 0e057442975cc466e123cf8894bc3f24 254 SMART SM00346 2 93 1.2E-17 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_20150 0e057442975cc466e123cf8894bc3f24 254 Pfam PF01614 Bacterial transcriptional regulator 121 243 9.0E-30 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal LH59_20150 0e057442975cc466e123cf8894bc3f24 254 Gene3D G3DSA:3.30.450.40 75 250 1.1E-58 T 14-10-2018 IPR029016 GAF-like domain superfamily LH59_20150 0e057442975cc466e123cf8894bc3f24 254 SUPERFAMILY SSF46785 3 75 1.67E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_20150 0e057442975cc466e123cf8894bc3f24 254 SUPERFAMILY SSF55781 75 247 5.89E-52 T 14-10-2018 LH59_14690 ca1edd43df2690ba1f1d4ade9961a6a5 263 SUPERFAMILY SSF56524 59 262 6.28E-64 T 14-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 LH59_14690 ca1edd43df2690ba1f1d4ade9961a6a5 263 Gene3D G3DSA:3.90.420.10 88 262 6.2E-50 T 14-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 LH59_14690 ca1edd43df2690ba1f1d4ade9961a6a5 263 Pfam PF00174 Oxidoreductase molybdopterin binding domain 109 252 7.2E-32 T 14-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 LH59_13850 c97083752a8fb9fc22e30ff416b65908 365 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 172 360 3.4E-19 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_13850 c97083752a8fb9fc22e30ff416b65908 365 SUPERFAMILY SSF161098 155 345 1.96E-37 T 14-10-2018 IPR035906 MetI-like superfamily LH59_13850 c97083752a8fb9fc22e30ff416b65908 365 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 155 251 4.4E-16 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 LH59_13850 c97083752a8fb9fc22e30ff416b65908 365 Gene3D G3DSA:1.10.3720.10 147 365 5.9E-48 T 14-10-2018 IPR035906 MetI-like superfamily LH59_24900 411e627246298d76626575873860d3bb 688 SUPERFAMILY SSF47323 396 596 6.35E-30 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 LH59_24900 411e627246298d76626575873860d3bb 688 Gene3D G3DSA:1.10.730.10 399 540 2.1E-24 T 14-10-2018 LH59_24900 411e627246298d76626575873860d3bb 688 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 572 688 2.8E-39 T 14-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 LH59_24900 411e627246298d76626575873860d3bb 688 Gene3D G3DSA:2.40.50.140 573 688 4.7E-32 T 14-10-2018 LH59_24900 411e627246298d76626575873860d3bb 688 Gene3D G3DSA:2.20.28.20 139 173 3.1E-135 T 14-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 LH59_24900 411e627246298d76626575873860d3bb 688 Hamap MF_00098 Methionine--tRNA ligase [metG]. 3 561 37.332 T 14-10-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 LH59_24900 411e627246298d76626575873860d3bb 688 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 12 23 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 LH59_24900 411e627246298d76626575873860d3bb 688 SUPERFAMILY SSF50249 581 687 6.12E-29 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_24900 411e627246298d76626575873860d3bb 688 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 6 550 5.1E-147 T 14-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 LH59_24900 411e627246298d76626575873860d3bb 688 PRINTS PR01041 Methionyl-tRNA synthetase signature 7 20 1.7E-22 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 LH59_24900 411e627246298d76626575873860d3bb 688 PRINTS PR01041 Methionyl-tRNA synthetase signature 300 315 1.7E-22 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 LH59_24900 411e627246298d76626575873860d3bb 688 PRINTS PR01041 Methionyl-tRNA synthetase signature 39 53 1.7E-22 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 LH59_24900 411e627246298d76626575873860d3bb 688 PRINTS PR01041 Methionyl-tRNA synthetase signature 87 98 1.7E-22 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 LH59_24900 411e627246298d76626575873860d3bb 688 PRINTS PR01041 Methionyl-tRNA synthetase signature 394 405 1.7E-22 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 LH59_24900 411e627246298d76626575873860d3bb 688 PRINTS PR01041 Methionyl-tRNA synthetase signature 261 272 1.7E-22 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 LH59_24900 411e627246298d76626575873860d3bb 688 Gene3D G3DSA:3.40.50.620 6 394 3.1E-135 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LH59_24900 411e627246298d76626575873860d3bb 688 SUPERFAMILY SSF57770 139 173 3.14E-12 T 14-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 LH59_24900 411e627246298d76626575873860d3bb 688 Pfam PF09334 tRNA synthetases class I (M) 6 406 2.2E-136 T 14-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 LH59_24900 411e627246298d76626575873860d3bb 688 Pfam PF01588 Putative tRNA binding domain 588 669 1.7E-21 T 14-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 LH59_24900 411e627246298d76626575873860d3bb 688 SUPERFAMILY SSF52374 4 394 1.66E-89 T 14-10-2018 LH59_26050 27c3237efe4b13f53c503df88743d2c7 306 Gene3D G3DSA:3.40.190.290 94 301 3.7E-29 T 14-10-2018 LH59_26050 27c3237efe4b13f53c503df88743d2c7 306 Pfam PF03466 LysR substrate binding domain 92 297 1.9E-33 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_26050 27c3237efe4b13f53c503df88743d2c7 306 SUPERFAMILY SSF53850 87 300 2.17E-31 T 14-10-2018 LH59_26050 27c3237efe4b13f53c503df88743d2c7 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 65 5.6E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_26050 27c3237efe4b13f53c503df88743d2c7 306 SUPERFAMILY SSF46785 6 90 2.32E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_26050 27c3237efe4b13f53c503df88743d2c7 306 Gene3D G3DSA:1.10.10.10 6 91 1.5E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_21710 48ffbfd606782c58b8a9c810cdc6ea48 337 Gene3D G3DSA:3.10.310.10 7 335 1.1E-106 T 14-10-2018 LH59_21710 48ffbfd606782c58b8a9c810cdc6ea48 337 PIRSF PIRSF029792 1 337 2.6E-100 T 14-10-2018 IPR008794 Proline racemase family LH59_21710 48ffbfd606782c58b8a9c810cdc6ea48 337 SUPERFAMILY SSF54506 1 334 7.57E-95 T 14-10-2018 LH59_21710 48ffbfd606782c58b8a9c810cdc6ea48 337 Gene3D G3DSA:3.10.310.10 147 313 1.1E-106 T 14-10-2018 LH59_21710 48ffbfd606782c58b8a9c810cdc6ea48 337 Pfam PF05544 Proline racemase 9 334 4.7E-94 T 14-10-2018 IPR008794 Proline racemase family LH59_09755 2df1e637ad274c1a20df741b5745bd17 333 SUPERFAMILY SSF53850 122 287 3.33E-7 T 14-10-2018 LH59_09755 2df1e637ad274c1a20df741b5745bd17 333 Gene3D G3DSA:3.40.190.150 36 322 9.1E-102 T 14-10-2018 LH59_09755 2df1e637ad274c1a20df741b5745bd17 333 Gene3D G3DSA:3.40.190.10 134 257 9.1E-102 T 14-10-2018 LH59_09755 2df1e637ad274c1a20df741b5745bd17 333 PIRSF PIRSF017082 5 332 4.5E-76 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_09755 2df1e637ad274c1a20df741b5745bd17 333 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 57 329 7.1E-76 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_14270 f1e7ec19c38d5d84969ba71dacf0743f 282 PIRSF PIRSF039085 12 257 1.9E-99 T 14-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 LH59_14270 f1e7ec19c38d5d84969ba71dacf0743f 282 SMART SM00382 40 237 4.4E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_14270 f1e7ec19c38d5d84969ba71dacf0743f 282 Gene3D G3DSA:3.40.50.300 14 259 1.1E-75 T 14-10-2018 LH59_14270 f1e7ec19c38d5d84969ba71dacf0743f 282 SUPERFAMILY SSF52540 15 251 3.96E-72 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_14270 f1e7ec19c38d5d84969ba71dacf0743f 282 Pfam PF00005 ABC transporter 31 181 3.9E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_14270 f1e7ec19c38d5d84969ba71dacf0743f 282 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_00975 dcfeb8bf1070707777450c8106a85bfd 426 Gene3D G3DSA:3.65.10.10 6 413 5.0E-162 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 LH59_00975 dcfeb8bf1070707777450c8106a85bfd 426 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 416 43.444 T 14-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 LH59_00975 dcfeb8bf1070707777450c8106a85bfd 426 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 415 1.4E-170 T 14-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 LH59_00975 dcfeb8bf1070707777450c8106a85bfd 426 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 405 4.7E-104 T 14-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 LH59_00975 dcfeb8bf1070707777450c8106a85bfd 426 Gene3D G3DSA:3.65.10.10 21 230 5.0E-162 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 LH59_00975 dcfeb8bf1070707777450c8106a85bfd 426 SUPERFAMILY SSF55205 1 416 3.27E-137 T 14-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 LH59_19595 c87988c0afdec02fac66bfb74d9a8317 269 SUPERFAMILY SSF51735 110 253 8.49E-32 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_19595 c87988c0afdec02fac66bfb74d9a8317 269 SUPERFAMILY SSF53223 3 107 1.04E-23 T 14-10-2018 LH59_19595 c87988c0afdec02fac66bfb74d9a8317 269 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 13 96 3.3E-20 T 14-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 LH59_19595 c87988c0afdec02fac66bfb74d9a8317 269 Gene3D G3DSA:3.40.50.720 110 249 6.2E-76 T 14-10-2018 LH59_19595 c87988c0afdec02fac66bfb74d9a8317 269 Gene3D G3DSA:3.40.50.10860 8 109 6.2E-76 T 14-10-2018 LH59_28185 b6a2375b445a911c3a980a294c650985 450 SUPERFAMILY SSF116878 124 450 9.55E-48 T 14-10-2018 LH59_28185 b6a2375b445a911c3a980a294c650985 450 Pfam PF10396 GTP-binding protein TrmE N-terminus 6 123 4.2E-38 T 14-10-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 LH59_28185 b6a2375b445a911c3a980a294c650985 450 Gene3D G3DSA:1.20.120.430 125 450 6.7E-100 T 14-10-2018 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 LH59_28185 b6a2375b445a911c3a980a294c650985 450 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 221 340 9.1E-20 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 LH59_28185 b6a2375b445a911c3a980a294c650985 450 SUPERFAMILY SSF52540 71 367 6.9E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_28185 b6a2375b445a911c3a980a294c650985 450 Pfam PF12631 MnmE helical domain 126 447 7.8E-55 T 14-10-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 LH59_28185 b6a2375b445a911c3a980a294c650985 450 Gene3D G3DSA:3.30.1360.120 1 124 1.8E-42 T 14-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 LH59_28185 b6a2375b445a911c3a980a294c650985 450 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 11 450 1.5E-99 T 14-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 LH59_28185 b6a2375b445a911c3a980a294c650985 450 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 5 450 32.654 T 14-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 LH59_28185 b6a2375b445a911c3a980a294c650985 450 Pfam PF01926 50S ribosome-binding GTPase 222 335 1.3E-23 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 LH59_28185 b6a2375b445a911c3a980a294c650985 450 Gene3D G3DSA:3.40.50.300 220 377 6.7E-100 T 14-10-2018 LH59_18180 8384798500d0e643a90f658747a14f32 396 Gene3D G3DSA:3.50.50.60 5 329 1.5E-88 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_18180 8384798500d0e643a90f658747a14f32 396 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 135 8.5E-10 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LH59_18180 8384798500d0e643a90f658747a14f32 396 SUPERFAMILY SSF51905 1 144 3.89E-23 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_18180 8384798500d0e643a90f658747a14f32 396 SUPERFAMILY SSF51905 213 387 3.99E-9 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_18180 8384798500d0e643a90f658747a14f32 396 SUPERFAMILY SSF51905 120 262 1.35E-21 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_18180 8384798500d0e643a90f658747a14f32 396 Gene3D G3DSA:3.50.50.60 116 271 1.5E-88 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_24470 0b1677ba1b0530f38dac8703ca12f55c 83 Gene3D G3DSA:3.30.70.20 2 81 1.1E-32 T 14-10-2018 LH59_24470 0b1677ba1b0530f38dac8703ca12f55c 83 Pfam PF00037 4Fe-4S binding domain 6 25 5.1E-6 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain LH59_24470 0b1677ba1b0530f38dac8703ca12f55c 83 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 9 20 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site LH59_24470 0b1677ba1b0530f38dac8703ca12f55c 83 SUPERFAMILY SSF54862 5 77 7.15E-20 T 14-10-2018 LH59_07080 252a655ac53fd0dda7778bf22296184d 118 SUPERFAMILY SSF49503 16 115 1.98E-14 T 14-10-2018 IPR008972 Cupredoxin LH59_07080 252a655ac53fd0dda7778bf22296184d 118 Gene3D G3DSA:2.60.40.420 20 115 3.3E-11 T 14-10-2018 IPR008972 Cupredoxin LH59_07080 252a655ac53fd0dda7778bf22296184d 118 Pfam PF13473 Cupredoxin-like domain 16 114 1.3E-23 T 14-10-2018 IPR028096 EfeO-type cupredoxin-like domain LH59_14005 1192d2b45e3776af981830bc62f96b39 304 SUPERFAMILY SSF51569 13 302 1.78E-68 T 14-10-2018 LH59_14005 1192d2b45e3776af981830bc62f96b39 304 PIRSF PIRSF001365 7 304 4.2E-57 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_14005 1192d2b45e3776af981830bc62f96b39 304 Hamap MF_00694 Probable 5-dehydro-4-deoxyglucarate dehydratase. 11 302 44.28 T 14-10-2018 IPR017655 5-dehydro-4-deoxyglucarate dehydratase GO:0016052|GO:0047448 KEGG: 00053+4.2.1.41|MetaCyc: PWY-6486|MetaCyc: PWY-6497|MetaCyc: PWY-6499|MetaCyc: PWY-6501 LH59_14005 1192d2b45e3776af981830bc62f96b39 304 TIGRFAM TIGR03249 KdgD: 5-dehydro-4-deoxyglucarate dehydratase 4 301 1.9E-134 T 14-10-2018 IPR017655 5-dehydro-4-deoxyglucarate dehydratase GO:0016052|GO:0047448 KEGG: 00053+4.2.1.41|MetaCyc: PWY-6486|MetaCyc: PWY-6497|MetaCyc: PWY-6499|MetaCyc: PWY-6501 LH59_14005 1192d2b45e3776af981830bc62f96b39 304 SMART SM01130 11 302 2.7E-77 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_14005 1192d2b45e3776af981830bc62f96b39 304 Pfam PF00701 Dihydrodipicolinate synthetase family 13 299 1.1E-51 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_14005 1192d2b45e3776af981830bc62f96b39 304 Gene3D G3DSA:3.20.20.70 2 302 2.2E-97 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_16215 879974e3d26d71d57731890da8129a50 491 Pfam PF01494 FAD binding domain 46 96 6.4E-5 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 LH59_16215 879974e3d26d71d57731890da8129a50 491 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 126 265 1.5E-16 T 14-10-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase LH59_16215 879974e3d26d71d57731890da8129a50 491 SUPERFAMILY SSF51905 46 381 1.75E-26 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_16215 879974e3d26d71d57731890da8129a50 491 Gene3D G3DSA:3.50.50.60 37 405 1.8E-43 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_16215 879974e3d26d71d57731890da8129a50 491 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 47 66 3.0E-6 T 14-10-2018 LH59_16215 879974e3d26d71d57731890da8129a50 491 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 182 200 3.0E-6 T 14-10-2018 LH59_16215 879974e3d26d71d57731890da8129a50 491 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 227 245 3.0E-6 T 14-10-2018 LH59_16215 879974e3d26d71d57731890da8129a50 491 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 46 68 1.6E-9 T 14-10-2018 LH59_16215 879974e3d26d71d57731890da8129a50 491 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 185 194 1.6E-9 T 14-10-2018 LH59_16215 879974e3d26d71d57731890da8129a50 491 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 227 252 1.6E-9 T 14-10-2018 LH59_03310 6770ffb587257d8770b774490464843a 270 SUPERFAMILY SSF52540 17 245 3.39E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_03310 6770ffb587257d8770b774490464843a 270 SMART SM00382 45 226 1.7E-19 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_03310 6770ffb587257d8770b774490464843a 270 Pfam PF00005 ABC transporter 36 175 9.2E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_03310 6770ffb587257d8770b774490464843a 270 Gene3D G3DSA:3.40.50.300 15 250 1.4E-67 T 14-10-2018 LH59_03310 6770ffb587257d8770b774490464843a 270 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_06685 28b3a90fbe8f4411762576861d1ea3b4 336 PIRSF PIRSF017617 1 336 5.5E-134 T 14-10-2018 IPR023603 Threonine aldolase LH59_06685 28b3a90fbe8f4411762576861d1ea3b4 336 SUPERFAMILY SSF53383 1 335 4.08E-114 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_06685 28b3a90fbe8f4411762576861d1ea3b4 336 Pfam PF01212 Beta-eliminating lyase 3 283 1.8E-90 T 14-10-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 LH59_06685 28b3a90fbe8f4411762576861d1ea3b4 336 Gene3D G3DSA:3.40.640.10 1 245 4.6E-94 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_06685 28b3a90fbe8f4411762576861d1ea3b4 336 Gene3D G3DSA:3.90.1150.10 246 336 8.9E-26 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_19770 ce484e9bf154c630d4c69c784dd9cf6d 468 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 163 176 - T 14-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 LH59_19770 ce484e9bf154c630d4c69c784dd9cf6d 468 Gene3D G3DSA:3.40.50.300 126 310 2.0E-59 T 14-10-2018 LH59_19770 ce484e9bf154c630d4c69c784dd9cf6d 468 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 225 240 - T 14-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 LH59_19770 ce484e9bf154c630d4c69c784dd9cf6d 468 Pfam PF02954 Bacterial regulatory protein, Fis family 412 451 6.2E-11 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 LH59_19770 ce484e9bf154c630d4c69c784dd9cf6d 468 Gene3D G3DSA:1.10.10.60 397 454 2.8E-10 T 14-10-2018 LH59_19770 ce484e9bf154c630d4c69c784dd9cf6d 468 Pfam PF00158 Sigma-54 interaction domain 140 305 7.4E-63 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 LH59_19770 ce484e9bf154c630d4c69c784dd9cf6d 468 SMART SM00382 159 302 1.1E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_19770 ce484e9bf154c630d4c69c784dd9cf6d 468 SUPERFAMILY SSF52540 139 366 1.16E-54 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_19770 ce484e9bf154c630d4c69c784dd9cf6d 468 SUPERFAMILY SSF46689 409 453 7.53E-8 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_06615 5702a9d08707f76f1e7bc984462a69e5 501 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 186 493 5.2E-121 T 14-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 LH59_06615 5702a9d08707f76f1e7bc984462a69e5 501 Gene3D G3DSA:3.40.220.10 1 180 7.5E-32 T 14-10-2018 LH59_06615 5702a9d08707f76f1e7bc984462a69e5 501 Gene3D G3DSA:3.40.630.10 181 501 4.2E-134 T 14-10-2018 LH59_06615 5702a9d08707f76f1e7bc984462a69e5 501 SUPERFAMILY SSF52949 1 184 1.88E-30 T 14-10-2018 LH59_06615 5702a9d08707f76f1e7bc984462a69e5 501 SUPERFAMILY SSF53187 179 499 2.48E-118 T 14-10-2018 LH59_06615 5702a9d08707f76f1e7bc984462a69e5 501 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 4 501 35.928 T 14-10-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 LH59_06615 5702a9d08707f76f1e7bc984462a69e5 501 PRINTS PR00481 Cytosol aminopeptidase signature 378 393 4.8E-54 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 LH59_06615 5702a9d08707f76f1e7bc984462a69e5 501 PRINTS PR00481 Cytosol aminopeptidase signature 291 312 4.8E-54 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 LH59_06615 5702a9d08707f76f1e7bc984462a69e5 501 PRINTS PR00481 Cytosol aminopeptidase signature 328 349 4.8E-54 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 LH59_06615 5702a9d08707f76f1e7bc984462a69e5 501 PRINTS PR00481 Cytosol aminopeptidase signature 269 286 4.8E-54 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 LH59_06615 5702a9d08707f76f1e7bc984462a69e5 501 PRINTS PR00481 Cytosol aminopeptidase signature 350 370 4.8E-54 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 LH59_06615 5702a9d08707f76f1e7bc984462a69e5 501 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 354 361 - T 14-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 LH59_06615 5702a9d08707f76f1e7bc984462a69e5 501 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 20 142 2.0E-20 T 14-10-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 LH59_01435 5ae22e634cf727387776be642a4318a2 96 Pfam PF02583 Metal-sensitive transcriptional repressor 7 92 1.6E-18 T 14-10-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 LH59_01435 5ae22e634cf727387776be642a4318a2 96 Gene3D G3DSA:1.20.58.1000 1 96 8.3E-28 T 14-10-2018 IPR038390 Metal-sensitive transcriptional repressor superfamily LH59_26405 c43d1862aa67e44e3d8c30bf4e5f3ae2 231 Gene3D G3DSA:3.40.50.2020 103 231 1.4E-18 T 14-10-2018 LH59_26405 c43d1862aa67e44e3d8c30bf4e5f3ae2 231 Pfam PF00156 Phosphoribosyl transferase domain 129 229 4.2E-8 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 LH59_26405 c43d1862aa67e44e3d8c30bf4e5f3ae2 231 SUPERFAMILY SSF53271 53 230 8.0E-32 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like LH59_08940 5240904f787e160d9914be484ddf9dd5 396 Pfam PF06433 Methylamine dehydrogenase heavy chain (MADH) 50 366 2.2E-45 T 14-10-2018 IPR009451 Amine dehydrogenase heavy chain GO:0030058|GO:0042597|GO:0055114 KEGG: 00680+1.4.9.1|MetaCyc: PWY-6967 LH59_08940 5240904f787e160d9914be484ddf9dd5 396 Gene3D G3DSA:2.130.10.10 47 391 1.3E-130 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 LH59_08940 5240904f787e160d9914be484ddf9dd5 396 SUPERFAMILY SSF50969 23 369 3.77E-73 T 14-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like LH59_10880 b47310fae045823016c3bdadf147c9e4 228 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 17 217 1.2E-31 T 14-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 LH59_10880 b47310fae045823016c3bdadf147c9e4 228 Pfam PF01914 MarC family integral membrane protein 10 220 8.4E-51 T 14-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 LH59_08490 1c4c6e281a7bd447ee05bbb2914224cd 245 Gene3D G3DSA:3.30.1330.30 1 77 1.5E-21 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like LH59_08490 1c4c6e281a7bd447ee05bbb2914224cd 245 SUPERFAMILY SSF75217 83 244 1.11E-48 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases LH59_08490 1c4c6e281a7bd447ee05bbb2914224cd 245 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 7 80 7.0E-16 T 14-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 LH59_08490 1c4c6e281a7bd447ee05bbb2914224cd 245 SMART SM00967 6 82 3.5E-17 T 14-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 LH59_08490 1c4c6e281a7bd447ee05bbb2914224cd 245 Pfam PF00588 SpoU rRNA Methylase family 97 237 2.6E-39 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 LH59_08490 1c4c6e281a7bd447ee05bbb2914224cd 245 SUPERFAMILY SSF55315 3 77 8.48E-18 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like LH59_08490 1c4c6e281a7bd447ee05bbb2914224cd 245 Hamap MF_01887 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB [rlmB]. 4 244 44.118 T 14-10-2018 IPR024915 23S rRNA (guanosine-2-O-)-methyltransferase RlmB LH59_08490 1c4c6e281a7bd447ee05bbb2914224cd 245 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 5 243 4.3E-72 T 14-10-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 LH59_08490 1c4c6e281a7bd447ee05bbb2914224cd 245 Gene3D G3DSA:3.40.1280.10 80 244 5.3E-57 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal LH59_10860 f644d0d282d1d33e45ef1c83e27da3f7 346 Gene3D G3DSA:1.10.260.40 1 64 1.6E-15 T 14-10-2018 LH59_10860 f644d0d282d1d33e45ef1c83e27da3f7 346 Pfam PF00356 Bacterial regulatory proteins, lacI family 8 58 8.6E-7 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 LH59_10860 f644d0d282d1d33e45ef1c83e27da3f7 346 Pfam PF13377 Periplasmic binding protein-like domain 181 340 4.4E-34 T 14-10-2018 LH59_10860 f644d0d282d1d33e45ef1c83e27da3f7 346 SMART SM00354 6 81 1.1E-16 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 LH59_10860 f644d0d282d1d33e45ef1c83e27da3f7 346 SUPERFAMILY SSF47413 6 69 1.22E-10 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 LH59_10860 f644d0d282d1d33e45ef1c83e27da3f7 346 Gene3D G3DSA:3.40.50.2300 65 319 2.5E-76 T 14-10-2018 LH59_10860 f644d0d282d1d33e45ef1c83e27da3f7 346 SUPERFAMILY SSF53822 70 341 3.44E-71 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_10860 f644d0d282d1d33e45ef1c83e27da3f7 346 Gene3D G3DSA:3.40.50.2300 173 302 2.5E-76 T 14-10-2018 LH59_10600 a904f714160af0158f88ae76fc4857fb 318 PIRSF PIRSF017082 1 315 2.8E-73 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_10600 a904f714160af0158f88ae76fc4857fb 318 SUPERFAMILY SSF53850 111 273 3.48E-16 T 14-10-2018 LH59_10600 a904f714160af0158f88ae76fc4857fb 318 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 307 2.1E-68 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_10600 a904f714160af0158f88ae76fc4857fb 318 Gene3D G3DSA:3.40.190.10 124 243 4.5E-97 T 14-10-2018 LH59_10600 a904f714160af0158f88ae76fc4857fb 318 Gene3D G3DSA:3.40.190.150 26 308 4.5E-97 T 14-10-2018 LH59_27225 4f6ee76a778a58824e3059ad2f85cc25 214 SUPERFAMILY SSF55681 7 206 7.71E-58 T 14-10-2018 LH59_27225 4f6ee76a778a58824e3059ad2f85cc25 214 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 66 81 - T 14-10-2018 IPR020605 Octanoyltransferase, conserved site GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 LH59_27225 4f6ee76a778a58824e3059ad2f85cc25 214 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 70 124 1.0E-15 T 14-10-2018 LH59_27225 4f6ee76a778a58824e3059ad2f85cc25 214 Gene3D G3DSA:3.30.930.10 2 205 1.8E-54 T 14-10-2018 LH59_27225 4f6ee76a778a58824e3059ad2f85cc25 214 Hamap MF_00013 Octanoyltransferase [lipB]. 2 209 34.444 T 14-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 LH59_27225 4f6ee76a778a58824e3059ad2f85cc25 214 Pfam PF03099 Biotin/lipoate A/B protein ligase family 53 162 3.8E-8 T 14-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 LH59_27225 4f6ee76a778a58824e3059ad2f85cc25 214 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 22 185 3.9E-50 T 14-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 LH59_27225 4f6ee76a778a58824e3059ad2f85cc25 214 PIRSF PIRSF016262 1 212 1.7E-53 T 14-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 LH59_00005 be924fd49c13f2809f030908494e969b 486 SUPERFAMILY SSF48295 382 485 3.14E-36 T 14-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 LH59_00005 be924fd49c13f2809f030908494e969b 486 SUPERFAMILY SSF52540 150 361 3.17E-44 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_00005 be924fd49c13f2809f030908494e969b 486 Gene3D G3DSA:3.40.50.300 148 315 7.4E-48 T 14-10-2018 LH59_00005 be924fd49c13f2809f030908494e969b 486 ProSitePatterns PS01008 DnaA protein signature. 444 463 - T 14-10-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 LH59_00005 be924fd49c13f2809f030908494e969b 486 Pfam PF00308 Bacterial dnaA protein 150 367 4.4E-86 T 14-10-2018 IPR013317 Chromosomal replication initiator protein DnaA LH59_00005 be924fd49c13f2809f030908494e969b 486 Gene3D G3DSA:1.10.1750.10 388 485 6.9E-35 T 14-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 LH59_00005 be924fd49c13f2809f030908494e969b 486 Gene3D G3DSA:3.30.300.180 2 108 3.8E-23 T 14-10-2018 IPR038454 DnaA, N-terminal domain superfamily LH59_00005 be924fd49c13f2809f030908494e969b 486 Gene3D G3DSA:1.10.8.60 316 387 4.9E-21 T 14-10-2018 LH59_00005 be924fd49c13f2809f030908494e969b 486 SMART SM00760 394 463 3.0E-43 T 14-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 LH59_00005 be924fd49c13f2809f030908494e969b 486 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 395 463 2.3E-31 T 14-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 LH59_00005 be924fd49c13f2809f030908494e969b 486 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 5 484 1.2E-164 T 14-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 LH59_00005 be924fd49c13f2809f030908494e969b 486 SMART SM00382 182 316 2.5E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_00005 be924fd49c13f2809f030908494e969b 486 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 215 229 3.3E-49 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like LH59_00005 be924fd49c13f2809f030908494e969b 486 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 444 463 3.3E-49 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like LH59_00005 be924fd49c13f2809f030908494e969b 486 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 247 261 3.3E-49 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like LH59_00005 be924fd49c13f2809f030908494e969b 486 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 183 203 3.3E-49 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like LH59_00005 be924fd49c13f2809f030908494e969b 486 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 281 308 3.3E-49 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like LH59_00005 be924fd49c13f2809f030908494e969b 486 Pfam PF11638 DnaA N-terminal domain 3 66 5.8E-18 T 14-10-2018 IPR024633 DnaA N-terminal domain LH59_00005 be924fd49c13f2809f030908494e969b 486 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 2 485 31.652 T 14-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 LH59_10515 b3de1538e27ca84daf0a8845dcc9d99e 212 TIGRFAM TIGR01189 ccmA: heme ABC exporter, ATP-binding protein CcmA 13 196 3.3E-50 T 14-10-2018 IPR005895 ABC transporter, haem export, CcmA GO:0005215|GO:0017004 LH59_10515 b3de1538e27ca84daf0a8845dcc9d99e 212 SMART SM00382 22 201 2.9E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_10515 b3de1538e27ca84daf0a8845dcc9d99e 212 Pfam PF00005 ABC transporter 16 152 5.9E-21 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_10515 b3de1538e27ca84daf0a8845dcc9d99e 212 SUPERFAMILY SSF52540 12 192 1.12E-35 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_10515 b3de1538e27ca84daf0a8845dcc9d99e 212 Gene3D G3DSA:3.40.50.300 4 212 4.9E-37 T 14-10-2018 LH59_18495 f0e266d06e8732a945d0bd2e2eeee4ff 169 Pfam PF13508 Acetyltransferase (GNAT) domain 49 127 1.4E-8 T 14-10-2018 IPR000182 GNAT domain LH59_18495 f0e266d06e8732a945d0bd2e2eeee4ff 169 Gene3D G3DSA:3.40.630.30 1 163 9.6E-46 T 14-10-2018 LH59_18495 f0e266d06e8732a945d0bd2e2eeee4ff 169 SUPERFAMILY SSF55729 1 143 5.57E-26 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_02720 613cdea9e14ccd82693d6b36c76ea947 212 Pfam PF14497 Glutathione S-transferase, C-terminal domain 118 199 9.5E-8 T 14-10-2018 IPR004046 Glutathione S-transferase, C-terminal LH59_02720 613cdea9e14ccd82693d6b36c76ea947 212 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 79 6.8E-14 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 LH59_02720 613cdea9e14ccd82693d6b36c76ea947 212 Gene3D G3DSA:3.40.30.10 1 87 1.2E-23 T 14-10-2018 LH59_02720 613cdea9e14ccd82693d6b36c76ea947 212 TIGRFAM TIGR01262 maiA: maleylacetoacetate isomerase 2 210 5.9E-84 T 14-10-2018 IPR005955 Glutathione S-transferases, class Zeta GO:0003824|GO:0005737|GO:0009072 Reactome: R-HSA-156590|Reactome: R-HSA-204174|Reactome: R-HSA-71182 LH59_02720 613cdea9e14ccd82693d6b36c76ea947 212 SUPERFAMILY SSF52833 1 84 5.49E-23 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_02720 613cdea9e14ccd82693d6b36c76ea947 212 Gene3D G3DSA:1.20.1050.10 88 212 2.3E-52 T 14-10-2018 LH59_02720 613cdea9e14ccd82693d6b36c76ea947 212 SUPERFAMILY SSF47616 80 209 1.09E-35 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily LH59_23315 1b97b66ed46446459357d463b4984ec7 146 SUPERFAMILY SSF110087 5 129 3.66E-41 T 14-10-2018 IPR036182 Copper chaperone PCuAC superfamily LH59_23315 1b97b66ed46446459357d463b4984ec7 146 Pfam PF04314 Copper chaperone PCu(A)C 17 119 6.6E-35 T 14-10-2018 IPR007410 Copper chaperone PCuAC LH59_23315 1b97b66ed46446459357d463b4984ec7 146 Gene3D G3DSA:2.60.40.1890 20 133 4.5E-35 T 14-10-2018 IPR036182 Copper chaperone PCuAC superfamily LH59_02465 df1df161692cadacf739f39556308729 466 Gene3D G3DSA:1.10.287.130 185 302 1.4E-21 T 14-10-2018 LH59_02465 df1df161692cadacf739f39556308729 466 SUPERFAMILY SSF47384 218 301 1.59E-16 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 LH59_02465 df1df161692cadacf739f39556308729 466 SMART SM00387 344 455 1.2E-32 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_02465 df1df161692cadacf739f39556308729 466 Pfam PF00512 His Kinase A (phospho-acceptor) domain 237 301 1.2E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_02465 df1df161692cadacf739f39556308729 466 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 348 451 2.4E-17 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_02465 df1df161692cadacf739f39556308729 466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 381 395 8.2E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_02465 df1df161692cadacf739f39556308729 466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 409 8.2E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_02465 df1df161692cadacf739f39556308729 466 PRINTS PR00344 Bacterial sensor protein C-terminal signature 416 434 8.2E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_02465 df1df161692cadacf739f39556308729 466 SMART SM00388 235 301 1.1E-14 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_02465 df1df161692cadacf739f39556308729 466 SUPERFAMILY SSF55874 290 451 7.86E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_02465 df1df161692cadacf739f39556308729 466 Gene3D G3DSA:3.30.565.10 304 452 4.2E-31 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_02465 df1df161692cadacf739f39556308729 466 SMART SM00304 181 234 3.7E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_02465 df1df161692cadacf739f39556308729 466 TIGRFAM TIGR01386 cztS_silS_copS: heavy metal sensor kinase 7 445 3.1E-121 T 14-10-2018 IPR006290 Heavy metal sensor kinase GO:0000160|GO:0004673|GO:0016020 LH59_00200 de24cef01d89037a4ee4b34141c89858 385 SUPERFAMILY SSF54373 241 323 1.15E-10 T 14-10-2018 LH59_00200 de24cef01d89037a4ee4b34141c89858 385 Gene3D G3DSA:3.50.50.60 19 363 1.7E-74 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_00200 de24cef01d89037a4ee4b34141c89858 385 Pfam PF01266 FAD dependent oxidoreductase 19 360 3.8E-47 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 LH59_00200 de24cef01d89037a4ee4b34141c89858 385 SUPERFAMILY SSF51905 18 381 1.67E-40 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_00200 de24cef01d89037a4ee4b34141c89858 385 Gene3D G3DSA:3.30.9.10 105 324 1.7E-74 T 14-10-2018 LH59_12310 109dd32e2d6d93b5fd9cfabe33d0ae54 257 Gene3D G3DSA:1.10.3720.10 55 253 1.9E-26 T 14-10-2018 IPR035906 MetI-like superfamily LH59_12310 109dd32e2d6d93b5fd9cfabe33d0ae54 257 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 238 1.5E-23 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_12310 109dd32e2d6d93b5fd9cfabe33d0ae54 257 SUPERFAMILY SSF161098 58 240 3.27E-29 T 14-10-2018 IPR035906 MetI-like superfamily LH59_11865 079ff5bf901eb26395aab315e1e28a8a 429 Gene3D G3DSA:3.40.50.720 194 429 5.5E-85 T 14-10-2018 LH59_11865 079ff5bf901eb26395aab315e1e28a8a 429 PIRSF PIRSF000185 18 429 1.0E-160 T 14-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 LH59_11865 079ff5bf901eb26395aab315e1e28a8a 429 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 48 176 3.6E-55 T 14-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 LH59_11865 079ff5bf901eb26395aab315e1e28a8a 429 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 227 247 4.6E-33 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 LH59_11865 079ff5bf901eb26395aab315e1e28a8a 429 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 185 207 4.6E-33 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 LH59_11865 079ff5bf901eb26395aab315e1e28a8a 429 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 354 365 4.6E-33 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 LH59_11865 079ff5bf901eb26395aab315e1e28a8a 429 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 105 119 4.6E-33 T 14-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 LH59_11865 079ff5bf901eb26395aab315e1e28a8a 429 SUPERFAMILY SSF53223 17 196 4.8E-68 T 14-10-2018 LH59_11865 079ff5bf901eb26395aab315e1e28a8a 429 SUPERFAMILY SSF51735 194 428 3.83E-75 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_11865 079ff5bf901eb26395aab315e1e28a8a 429 Gene3D G3DSA:1.10.8.1210 1 56 4.3E-24 T 14-10-2018 LH59_11865 079ff5bf901eb26395aab315e1e28a8a 429 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 113 126 - T 14-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 LH59_11865 079ff5bf901eb26395aab315e1e28a8a 429 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 194 426 5.2E-75 T 14-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 LH59_11865 079ff5bf901eb26395aab315e1e28a8a 429 Gene3D G3DSA:3.40.50.10860 57 192 7.7E-58 T 14-10-2018 LH59_11865 079ff5bf901eb26395aab315e1e28a8a 429 SMART SM00839 196 426 2.2E-95 T 14-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 LH59_00225 f0ff5d32cb42f3ae567f7c730e23751f 426 Gene3D G3DSA:3.20.20.140 53 360 1.0E-161 T 14-10-2018 LH59_00225 f0ff5d32cb42f3ae567f7c730e23751f 426 Gene3D G3DSA:2.30.40.10 8 405 1.0E-161 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 LH59_00225 f0ff5d32cb42f3ae567f7c730e23751f 426 SUPERFAMILY SSF51338 1 407 2.24E-14 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 LH59_00225 f0ff5d32cb42f3ae567f7c730e23751f 426 SUPERFAMILY SSF51556 52 371 7.61E-110 T 14-10-2018 IPR032466 Metal-dependent hydrolase LH59_00225 f0ff5d32cb42f3ae567f7c730e23751f 426 Pfam PF07969 Amidohydrolase family 40 400 1.0E-51 T 14-10-2018 IPR013108 Amidohydrolase 3 LH59_23505 3fa81e9e8bed71a3c52e10f184b9e926 122 Pfam PF07883 Cupin domain 40 92 4.9E-11 T 14-10-2018 IPR013096 Cupin 2, conserved barrel LH59_23505 3fa81e9e8bed71a3c52e10f184b9e926 122 Gene3D G3DSA:2.60.120.10 4 105 8.8E-35 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_23505 3fa81e9e8bed71a3c52e10f184b9e926 122 SUPERFAMILY SSF51182 1 109 1.13E-23 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_21800 1f276f20bc43bd3cf6ab2f9fb352edbe 323 SUPERFAMILY SSF46785 3 86 7.12E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_21800 1f276f20bc43bd3cf6ab2f9fb352edbe 323 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 1.2E-15 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_21800 1f276f20bc43bd3cf6ab2f9fb352edbe 323 Gene3D G3DSA:3.40.190.10 165 266 5.9E-51 T 14-10-2018 LH59_21800 1f276f20bc43bd3cf6ab2f9fb352edbe 323 SUPERFAMILY SSF53850 89 297 2.35E-40 T 14-10-2018 LH59_21800 1f276f20bc43bd3cf6ab2f9fb352edbe 323 Gene3D G3DSA:1.10.10.10 2 89 8.2E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_21800 1f276f20bc43bd3cf6ab2f9fb352edbe 323 Pfam PF03466 LysR substrate binding domain 88 294 8.7E-38 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_21800 1f276f20bc43bd3cf6ab2f9fb352edbe 323 Gene3D G3DSA:3.40.190.10 91 293 5.9E-51 T 14-10-2018 LH59_04905 82972754515f5657963d68a6f1365a50 326 Gene3D G3DSA:3.40.50.300 1 325 1.7E-100 T 14-10-2018 LH59_04905 82972754515f5657963d68a6f1365a50 326 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 316 9.6E-23 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_04905 82972754515f5657963d68a6f1365a50 326 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_04905 82972754515f5657963d68a6f1365a50 326 SUPERFAMILY SSF52540 4 253 5.98E-68 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_04905 82972754515f5657963d68a6f1365a50 326 SMART SM00382 33 232 2.1E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_04905 82972754515f5657963d68a6f1365a50 326 Pfam PF00005 ABC transporter 24 182 1.7E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_04905 82972754515f5657963d68a6f1365a50 326 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 298 2.6E-18 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_23275 666828bc95d3e6c2a083a8f468b20ef1 261 Gene3D G3DSA:3.40.190.10 34 248 7.5E-73 T 14-10-2018 LH59_23275 666828bc95d3e6c2a083a8f468b20ef1 261 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 58 71 - T 14-10-2018 IPR018313 Solute-binding protein family 3, conserved site LH59_23275 666828bc95d3e6c2a083a8f468b20ef1 261 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 37 254 1.2E-64 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_23275 666828bc95d3e6c2a083a8f468b20ef1 261 SMART SM00062 35 256 1.2E-69 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_23275 666828bc95d3e6c2a083a8f468b20ef1 261 SUPERFAMILY SSF53850 7 256 3.26E-69 T 14-10-2018 LH59_23275 666828bc95d3e6c2a083a8f468b20ef1 261 Gene3D G3DSA:3.40.190.10 118 217 7.5E-73 T 14-10-2018 LH59_27765 7296edbe7be7736b1a2ef266f5e1c82c 173 Gene3D G3DSA:3.30.230.10 81 173 3.9E-35 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup LH59_27765 7296edbe7be7736b1a2ef266f5e1c82c 173 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 17 170 4.8E-63 T 14-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 LH59_27765 7296edbe7be7736b1a2ef266f5e1c82c 173 Pfam PF00333 Ribosomal protein S5, N-terminal domain 18 81 3.5E-24 T 14-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 LH59_27765 7296edbe7be7736b1a2ef266f5e1c82c 173 Gene3D G3DSA:3.30.160.20 8 79 4.1E-26 T 14-10-2018 LH59_27765 7296edbe7be7736b1a2ef266f5e1c82c 173 Pfam PF03719 Ribosomal protein S5, C-terminal domain 94 164 3.1E-27 T 14-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 LH59_27765 7296edbe7be7736b1a2ef266f5e1c82c 173 ProSitePatterns PS00585 Ribosomal protein S5 signature. 35 67 - T 14-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site LH59_27765 7296edbe7be7736b1a2ef266f5e1c82c 173 SUPERFAMILY SSF54211 86 166 1.04E-24 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold LH59_27765 7296edbe7be7736b1a2ef266f5e1c82c 173 SUPERFAMILY SSF54768 15 82 9.42E-21 T 14-10-2018 LH59_27765 7296edbe7be7736b1a2ef266f5e1c82c 173 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 170 33.741 T 14-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 LH59_09870 5dbe6e02ed8e40a0189d5d88757ecfca 595 SUPERFAMILY SSF52540 341 586 9.85E-92 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_09870 5dbe6e02ed8e40a0189d5d88757ecfca 595 Gene3D G3DSA:1.20.1560.10 18 340 1.8E-126 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 LH59_09870 5dbe6e02ed8e40a0189d5d88757ecfca 595 SMART SM00382 376 562 3.4E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_09870 5dbe6e02ed8e40a0189d5d88757ecfca 595 Pfam PF00005 ABC transporter 367 516 9.7E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_09870 5dbe6e02ed8e40a0189d5d88757ecfca 595 Gene3D G3DSA:3.40.50.300 342 594 1.3E-94 T 14-10-2018 LH59_09870 5dbe6e02ed8e40a0189d5d88757ecfca 595 SUPERFAMILY SSF90123 13 337 3.14E-66 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 LH59_09870 5dbe6e02ed8e40a0189d5d88757ecfca 595 ProSitePatterns PS00211 ABC transporters family signature. 488 502 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_09870 5dbe6e02ed8e40a0189d5d88757ecfca 595 Pfam PF00664 ABC transporter transmembrane region 32 305 6.9E-43 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 LH59_14275 c6a651521d4bb06b2f895f9e68e5af13 272 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 269 1.5E-15 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_14275 c6a651521d4bb06b2f895f9e68e5af13 272 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 59 161 5.1E-20 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 LH59_14275 c6a651521d4bb06b2f895f9e68e5af13 272 Gene3D G3DSA:1.10.3720.10 50 271 2.9E-41 T 14-10-2018 IPR035906 MetI-like superfamily LH59_14275 c6a651521d4bb06b2f895f9e68e5af13 272 SUPERFAMILY SSF161098 59 255 6.54E-36 T 14-10-2018 IPR035906 MetI-like superfamily LH59_03195 e9670d56ca06d1140a804d3976ddf291 313 SUPERFAMILY SSF53613 3 298 9.2E-63 T 14-10-2018 IPR029056 Ribokinase-like LH59_03195 e9670d56ca06d1140a804d3976ddf291 313 Pfam PF00294 pfkB family carbohydrate kinase 36 294 8.0E-42 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB LH59_03195 e9670d56ca06d1140a804d3976ddf291 313 Gene3D G3DSA:3.40.1190.20 3 311 3.5E-104 T 14-10-2018 IPR029056 Ribokinase-like LH59_03535 7e0afaaa8bc898fab29d4a2695c7a075 111 Pfam PF01740 STAS domain 4 106 7.2E-19 T 14-10-2018 IPR002645 STAS domain LH59_03535 7e0afaaa8bc898fab29d4a2695c7a075 111 SUPERFAMILY SSF52091 1 108 1.55E-25 T 14-10-2018 IPR036513 STAS domain superfamily LH59_03535 7e0afaaa8bc898fab29d4a2695c7a075 111 Gene3D G3DSA:3.30.750.24 1 111 6.7E-29 T 14-10-2018 IPR036513 STAS domain superfamily LH59_03535 7e0afaaa8bc898fab29d4a2695c7a075 111 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 1 104 2.9E-23 T 14-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 LH59_05305 53871ea91f0570fe682ee77daf51dc2a 185 Pfam PF01025 GrpE 24 181 1.5E-46 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 LH59_05305 53871ea91f0570fe682ee77daf51dc2a 185 Gene3D G3DSA:2.30.22.10 127 182 1.5E-18 T 14-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 LH59_05305 53871ea91f0570fe682ee77daf51dc2a 185 ProSitePatterns PS01071 grpE protein signature. 138 180 - T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 LH59_05305 53871ea91f0570fe682ee77daf51dc2a 185 SUPERFAMILY SSF51064 131 183 4.05E-15 T 14-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 LH59_05305 53871ea91f0570fe682ee77daf51dc2a 185 Hamap MF_01151 Protein GrpE [grpE]. 5 182 19.302 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 LH59_05305 53871ea91f0570fe682ee77daf51dc2a 185 SUPERFAMILY SSF58014 31 124 2.62E-23 T 14-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 LH59_05305 53871ea91f0570fe682ee77daf51dc2a 185 Gene3D G3DSA:3.90.20.20 23 125 8.6E-25 T 14-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 LH59_05305 53871ea91f0570fe682ee77daf51dc2a 185 PRINTS PR00773 GrpE protein signature 135 150 5.5E-25 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 LH59_05305 53871ea91f0570fe682ee77daf51dc2a 185 PRINTS PR00773 GrpE protein signature 54 70 5.5E-25 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 LH59_05305 53871ea91f0570fe682ee77daf51dc2a 185 PRINTS PR00773 GrpE protein signature 82 97 5.5E-25 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 LH59_05305 53871ea91f0570fe682ee77daf51dc2a 185 PRINTS PR00773 GrpE protein signature 161 180 5.5E-25 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 LH59_17050 b83aa8dbd4a351e228259f7e33c4291d 229 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_17050 b83aa8dbd4a351e228259f7e33c4291d 229 Pfam PF00005 ABC transporter 28 175 1.9E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_17050 b83aa8dbd4a351e228259f7e33c4291d 229 Gene3D G3DSA:3.40.50.300 7 228 1.6E-61 T 14-10-2018 LH59_17050 b83aa8dbd4a351e228259f7e33c4291d 229 SUPERFAMILY SSF52540 9 227 1.15E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_17050 b83aa8dbd4a351e228259f7e33c4291d 229 SMART SM00382 37 225 8.2E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_16635 becd1dff985b4e8bb6e01ee7823d6f93 343 Gene3D G3DSA:3.40.190.170 28 341 4.6E-126 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily LH59_16635 becd1dff985b4e8bb6e01ee7823d6f93 343 SUPERFAMILY SSF53850 74 212 7.03E-6 T 14-10-2018 LH59_16635 becd1dff985b4e8bb6e01ee7823d6f93 343 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 35 324 4.2E-76 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 LH59_16635 becd1dff985b4e8bb6e01ee7823d6f93 343 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 36 276 1.8E-61 T 14-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 LH59_16635 becd1dff985b4e8bb6e01ee7823d6f93 343 PIRSF PIRSF006470 1 340 1.6E-85 T 14-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 LH59_01805 81dfd43505028701812d96637a308ba0 507 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 262 269 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 LH59_01805 81dfd43505028701812d96637a308ba0 507 Pfam PF00171 Aldehyde dehydrogenase family 28 494 2.0E-163 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 LH59_01805 81dfd43505028701812d96637a308ba0 507 Gene3D G3DSA:3.40.309.10 267 465 3.8E-162 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 LH59_01805 81dfd43505028701812d96637a308ba0 507 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 295 306 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 LH59_01805 81dfd43505028701812d96637a308ba0 507 SUPERFAMILY SSF53720 15 499 1.57E-161 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 LH59_01805 81dfd43505028701812d96637a308ba0 507 Gene3D G3DSA:3.40.605.10 24 493 3.8E-162 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 LH59_18505 56863e2b4ccc6909f63000134ee89838 610 SUPERFAMILY SSF90123 42 373 7.46E-16 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 LH59_18505 56863e2b4ccc6909f63000134ee89838 610 Pfam PF06472 ABC transporter transmembrane region 2 38 325 6.0E-78 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 LH59_18505 56863e2b4ccc6909f63000134ee89838 610 Pfam PF00005 ABC transporter 409 544 1.2E-17 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_18505 56863e2b4ccc6909f63000134ee89838 610 SUPERFAMILY SSF52540 384 589 7.99E-34 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_18505 56863e2b4ccc6909f63000134ee89838 610 Gene3D G3DSA:3.40.50.300 387 597 8.7E-36 T 14-10-2018 LH59_18505 56863e2b4ccc6909f63000134ee89838 610 SMART SM00382 418 591 2.7E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_10560 ab073f65bd22710164cc5fea4b2d73c0 227 SMART SM00345 20 78 1.0E-9 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_10560 ab073f65bd22710164cc5fea4b2d73c0 227 Pfam PF00392 Bacterial regulatory proteins, gntR family 20 78 5.6E-12 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_10560 ab073f65bd22710164cc5fea4b2d73c0 227 SUPERFAMILY SSF46785 18 82 3.9E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_10560 ab073f65bd22710164cc5fea4b2d73c0 227 SMART SM00895 88 212 9.7E-12 T 14-10-2018 IPR011711 GntR, C-terminal LH59_10560 ab073f65bd22710164cc5fea4b2d73c0 227 Gene3D G3DSA:1.20.120.530 82 224 2.5E-22 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_10560 ab073f65bd22710164cc5fea4b2d73c0 227 Pfam PF07729 FCD domain 88 210 1.4E-20 T 14-10-2018 IPR011711 GntR, C-terminal LH59_10560 ab073f65bd22710164cc5fea4b2d73c0 227 SUPERFAMILY SSF48008 85 218 3.4E-23 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_10560 ab073f65bd22710164cc5fea4b2d73c0 227 Gene3D G3DSA:1.10.10.10 2 79 5.0E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_15395 6a16ada6b2655286ccaddf43577410b8 444 Pfam PF03055 Retinal pigment epithelial membrane protein 12 439 2.4E-93 T 14-10-2018 IPR004294 Carotenoid oxygenase GO:0016702|GO:0055114 LH59_26435 70040a7a3fc2409d7c091e252bf6d1bb 773 SMART SM00387 636 754 1.5E-34 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_26435 70040a7a3fc2409d7c091e252bf6d1bb 773 SMART SM00388 513 585 2.1E-10 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_26435 70040a7a3fc2409d7c091e252bf6d1bb 773 Gene3D G3DSA:3.30.565.10 587 755 3.5E-42 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_26435 70040a7a3fc2409d7c091e252bf6d1bb 773 Gene3D G3DSA:1.20.1480.50 287 371 2.9E-9 T 14-10-2018 LH59_26435 70040a7a3fc2409d7c091e252bf6d1bb 773 PIRSF PIRSF037532 1 757 2.7E-238 T 14-10-2018 IPR017232 Signal transduction histidine kinase, nitrogen fixation and metabolism regulator LH59_26435 70040a7a3fc2409d7c091e252bf6d1bb 773 SUPERFAMILY SSF55785 374 503 3.24E-10 T 14-10-2018 IPR035965 PAS domain superfamily LH59_26435 70040a7a3fc2409d7c091e252bf6d1bb 773 SUPERFAMILY SSF55874 574 751 1.7E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_26435 70040a7a3fc2409d7c091e252bf6d1bb 773 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 636 749 4.4E-22 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_26435 70040a7a3fc2409d7c091e252bf6d1bb 773 Pfam PF00672 HAMP domain 316 364 1.3E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_26435 70040a7a3fc2409d7c091e252bf6d1bb 773 SUPERFAMILY SSF158472 317 365 1.96E-6 T 14-10-2018 LH59_26435 70040a7a3fc2409d7c091e252bf6d1bb 773 PRINTS PR00344 Bacterial sensor protein C-terminal signature 685 699 1.4E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_26435 70040a7a3fc2409d7c091e252bf6d1bb 773 PRINTS PR00344 Bacterial sensor protein C-terminal signature 703 713 1.4E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_26435 70040a7a3fc2409d7c091e252bf6d1bb 773 PRINTS PR00344 Bacterial sensor protein C-terminal signature 714 732 1.4E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_26435 70040a7a3fc2409d7c091e252bf6d1bb 773 Pfam PF08448 PAS fold 388 505 1.8E-5 T 14-10-2018 IPR013656 PAS fold-4 LH59_26435 70040a7a3fc2409d7c091e252bf6d1bb 773 SUPERFAMILY SSF47384 502 582 9.42E-10 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 LH59_26435 70040a7a3fc2409d7c091e252bf6d1bb 773 Gene3D G3DSA:1.10.287.130 504 582 8.7E-11 T 14-10-2018 LH59_26435 70040a7a3fc2409d7c091e252bf6d1bb 773 Gene3D G3DSA:3.30.450.20 372 503 4.9E-13 T 14-10-2018 LH59_26435 70040a7a3fc2409d7c091e252bf6d1bb 773 Pfam PF00512 His Kinase A (phospho-acceptor) domain 514 581 2.2E-8 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_26435 70040a7a3fc2409d7c091e252bf6d1bb 773 SMART SM00304 316 368 7.3E-11 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_04880 ff6d7ccff3ef8ef9d32ec9f06fe48bf4 741 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 463 607 1.7E-18 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 LH59_04880 ff6d7ccff3ef8ef9d32ec9f06fe48bf4 741 SUPERFAMILY SSF52518 21 200 6.87E-27 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold LH59_04880 ff6d7ccff3ef8ef9d32ec9f06fe48bf4 741 Gene3D G3DSA:3.40.50.970 3 202 8.6E-24 T 14-10-2018 LH59_04880 ff6d7ccff3ef8ef9d32ec9f06fe48bf4 741 SUPERFAMILY SSF52518 407 656 4.72E-31 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold LH59_04880 ff6d7ccff3ef8ef9d32ec9f06fe48bf4 741 Gene3D G3DSA:3.40.50.970 446 638 2.2E-14 T 14-10-2018 LH59_12885 84bfcb4e2c62383a42e1fb1e5114a269 233 Pfam PF00072 Response regulator receiver domain 5 113 1.9E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_12885 84bfcb4e2c62383a42e1fb1e5114a269 233 SUPERFAMILY SSF52172 2 130 2.85E-38 T 14-10-2018 IPR011006 CheY-like superfamily LH59_12885 84bfcb4e2c62383a42e1fb1e5114a269 233 SMART SM00448 2 112 3.1E-39 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_12885 84bfcb4e2c62383a42e1fb1e5114a269 233 SMART SM00862 147 223 9.5E-26 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_12885 84bfcb4e2c62383a42e1fb1e5114a269 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 223 1.1E-24 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_12885 84bfcb4e2c62383a42e1fb1e5114a269 233 Gene3D G3DSA:3.40.50.2300 1 126 2.7E-34 T 14-10-2018 LH59_12885 84bfcb4e2c62383a42e1fb1e5114a269 233 SUPERFAMILY SSF46894 124 224 8.22E-29 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LH59_12885 84bfcb4e2c62383a42e1fb1e5114a269 233 Gene3D G3DSA:1.10.10.10 127 232 7.5E-36 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_19450 7c677209abfe1bac7df75c7ef73b9cda 359 SUPERFAMILY SSF56112 19 335 3.79E-54 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily LH59_19450 7c677209abfe1bac7df75c7ef73b9cda 359 Pfam PF01636 Phosphotransferase enzyme family 44 279 7.9E-28 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase LH59_19450 7c677209abfe1bac7df75c7ef73b9cda 359 Gene3D G3DSA:3.90.1200.10 130 325 2.0E-25 T 14-10-2018 LH59_03670 6117c5876c35fc51adaebf89b314b98a 161 Pfam PF05232 Chlorhexidine efflux transporter 74 137 3.1E-26 T 14-10-2018 IPR007896 Chlorhexidine efflux transporter LH59_03670 6117c5876c35fc51adaebf89b314b98a 161 Pfam PF05232 Chlorhexidine efflux transporter 6 69 2.0E-24 T 14-10-2018 IPR007896 Chlorhexidine efflux transporter LH59_02315 a9e8691c66f370bae3a2a1f06f365d68 173 Gene3D G3DSA:2.40.128.20 12 173 6.8E-56 T 14-10-2018 IPR012674 Calycin LH59_02315 a9e8691c66f370bae3a2a1f06f365d68 173 PRINTS PR01171 Bacterial lipocalin signature 102 116 3.2E-12 T 14-10-2018 IPR002446 Lipocalin, bacterial GO:0005215 LH59_02315 a9e8691c66f370bae3a2a1f06f365d68 173 PRINTS PR01171 Bacterial lipocalin signature 119 127 3.2E-12 T 14-10-2018 IPR002446 Lipocalin, bacterial GO:0005215 LH59_02315 a9e8691c66f370bae3a2a1f06f365d68 173 PRINTS PR01171 Bacterial lipocalin signature 32 46 3.2E-12 T 14-10-2018 IPR002446 Lipocalin, bacterial GO:0005215 LH59_02315 a9e8691c66f370bae3a2a1f06f365d68 173 PRINTS PR01171 Bacterial lipocalin signature 134 145 3.2E-12 T 14-10-2018 IPR002446 Lipocalin, bacterial GO:0005215 LH59_02315 a9e8691c66f370bae3a2a1f06f365d68 173 ProSitePatterns PS00213 Lipocalin signature. 33 44 - T 14-10-2018 IPR022272 Lipocalin family conserved site LH59_02315 a9e8691c66f370bae3a2a1f06f365d68 173 Pfam PF08212 Lipocalin-like domain 32 172 1.3E-53 T 14-10-2018 IPR000566 Lipocalin/cytosolic fatty-acid binding domain LH59_02315 a9e8691c66f370bae3a2a1f06f365d68 173 PIRSF PIRSF036893 1 173 2.0E-60 T 14-10-2018 IPR022271 Lipocalin, ApoD type LH59_02315 a9e8691c66f370bae3a2a1f06f365d68 173 SUPERFAMILY SSF50814 9 172 1.78E-47 T 14-10-2018 IPR012674 Calycin LH59_26195 2c139b94d17689f6f1658eb1bb1afe06 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.2E-21 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_26195 2c139b94d17689f6f1658eb1bb1afe06 296 Pfam PF03466 LysR substrate binding domain 87 292 1.8E-21 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_26195 2c139b94d17689f6f1658eb1bb1afe06 296 Gene3D G3DSA:1.10.10.10 1 88 5.4E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_26195 2c139b94d17689f6f1658eb1bb1afe06 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.0E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_26195 2c139b94d17689f6f1658eb1bb1afe06 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.0E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_26195 2c139b94d17689f6f1658eb1bb1afe06 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.0E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_26195 2c139b94d17689f6f1658eb1bb1afe06 296 SUPERFAMILY SSF53850 88 293 3.91E-25 T 14-10-2018 LH59_26195 2c139b94d17689f6f1658eb1bb1afe06 296 Gene3D G3DSA:3.40.190.10 99 283 1.9E-45 T 14-10-2018 LH59_26195 2c139b94d17689f6f1658eb1bb1afe06 296 SUPERFAMILY SSF46785 1 104 1.04E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_26195 2c139b94d17689f6f1658eb1bb1afe06 296 Gene3D G3DSA:3.40.190.10 164 265 1.9E-45 T 14-10-2018 LH59_18330 3380ced99a97e9d9a28d698955daf8f4 312 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 193 215 - T 14-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site LH59_18330 3380ced99a97e9d9a28d698955daf8f4 312 Gene3D G3DSA:3.40.50.720 12 306 2.9E-92 T 14-10-2018 LH59_18330 3380ced99a97e9d9a28d698955daf8f4 312 SUPERFAMILY SSF52283 9 137 1.04E-23 T 14-10-2018 LH59_18330 3380ced99a97e9d9a28d698955daf8f4 312 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 14 307 1.2E-21 T 14-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 LH59_18330 3380ced99a97e9d9a28d698955daf8f4 312 Gene3D G3DSA:3.40.50.720 102 281 2.9E-92 T 14-10-2018 LH59_18330 3380ced99a97e9d9a28d698955daf8f4 312 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 111 283 6.3E-56 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 LH59_18330 3380ced99a97e9d9a28d698955daf8f4 312 SUPERFAMILY SSF51735 102 284 2.29E-54 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_18330 3380ced99a97e9d9a28d698955daf8f4 312 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 222 238 - T 14-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site LH59_09875 32e365badb7bf46657538a3520bf9a0e 275 Gene3D G3DSA:3.20.20.100 1 275 8.8E-116 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily LH59_09875 32e365badb7bf46657538a3520bf9a0e 275 Pfam PF00248 Aldo/keto reductase family 18 261 1.4E-50 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain LH59_09875 32e365badb7bf46657538a3520bf9a0e 275 PIRSF PIRSF000097 113 268 2.1E-49 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 LH59_09875 32e365badb7bf46657538a3520bf9a0e 275 PIRSF PIRSF000097 1 117 1.8E-44 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 LH59_09875 32e365badb7bf46657538a3520bf9a0e 275 PRINTS PR00069 Aldo-keto reductase signature 196 220 1.6E-45 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 LH59_09875 32e365badb7bf46657538a3520bf9a0e 275 PRINTS PR00069 Aldo-keto reductase signature 93 111 1.6E-45 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 LH59_09875 32e365badb7bf46657538a3520bf9a0e 275 PRINTS PR00069 Aldo-keto reductase signature 37 61 1.6E-45 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 LH59_09875 32e365badb7bf46657538a3520bf9a0e 275 PRINTS PR00069 Aldo-keto reductase signature 159 188 1.6E-45 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 LH59_09875 32e365badb7bf46657538a3520bf9a0e 275 PRINTS PR00069 Aldo-keto reductase signature 125 142 1.6E-45 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 LH59_09875 32e365badb7bf46657538a3520bf9a0e 275 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 125 142 - T 14-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 LH59_09875 32e365badb7bf46657538a3520bf9a0e 275 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 41 58 - T 14-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 LH59_09875 32e365badb7bf46657538a3520bf9a0e 275 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 229 244 - T 14-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 LH59_09875 32e365badb7bf46657538a3520bf9a0e 275 SUPERFAMILY SSF51430 6 266 3.14E-94 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily LH59_10535 cc37a1e44e5e23eb0f78c317de822e4a 105 Pfam PF03927 NapD protein 16 90 3.3E-27 T 14-10-2018 IPR005623 Chaperone NapD, nitrate reductase assembly LH59_10535 cc37a1e44e5e23eb0f78c317de822e4a 105 Hamap MF_02200 Chaperone NapD [napD]. 16 92 19.016 T 14-10-2018 IPR005623 Chaperone NapD, nitrate reductase assembly LH59_10535 cc37a1e44e5e23eb0f78c317de822e4a 105 Gene3D G3DSA:3.30.70.920 16 85 1.8E-21 T 14-10-2018 LH59_25810 e7c7a9cb6e4058f0568325cd2bc03058 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 188 1.1E-5 T 14-10-2018 LH59_25810 e7c7a9cb6e4058f0568325cd2bc03058 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 242 7.2E-70 T 14-10-2018 LH59_25810 e7c7a9cb6e4058f0568325cd2bc03058 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 6.6E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25810 e7c7a9cb6e4058f0568325cd2bc03058 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 6.6E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25810 e7c7a9cb6e4058f0568325cd2bc03058 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 6.6E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25810 e7c7a9cb6e4058f0568325cd2bc03058 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LH59_25810 e7c7a9cb6e4058f0568325cd2bc03058 245 Gene3D G3DSA:3.40.50.720 1 244 7.0E-83 T 14-10-2018 LH59_25810 e7c7a9cb6e4058f0568325cd2bc03058 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.6E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25810 e7c7a9cb6e4058f0568325cd2bc03058 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 1.6E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25810 e7c7a9cb6e4058f0568325cd2bc03058 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 1.6E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25810 e7c7a9cb6e4058f0568325cd2bc03058 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.6E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25810 e7c7a9cb6e4058f0568325cd2bc03058 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.6E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25810 e7c7a9cb6e4058f0568325cd2bc03058 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.6E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25810 e7c7a9cb6e4058f0568325cd2bc03058 245 SUPERFAMILY SSF51735 5 244 1.12E-83 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_25045 84b373f76331ef0acb5b50a6a725b3f3 325 PIRSF PIRSF017082 1 325 2.9E-80 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_25045 84b373f76331ef0acb5b50a6a725b3f3 325 SUPERFAMILY SSF53850 112 285 1.33E-12 T 14-10-2018 LH59_25045 84b373f76331ef0acb5b50a6a725b3f3 325 Gene3D G3DSA:3.40.190.150 29 315 3.9E-111 T 14-10-2018 LH59_25045 84b373f76331ef0acb5b50a6a725b3f3 325 Gene3D G3DSA:3.40.190.10 127 250 3.9E-111 T 14-10-2018 LH59_25045 84b373f76331ef0acb5b50a6a725b3f3 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 319 3.6E-84 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_18630 3b02eab6821fb236923f7280f94ab324 315 SUPERFAMILY SSF54909 8 310 1.79E-104 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel LH59_18630 3b02eab6821fb236923f7280f94ab324 315 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 9 305 9.2E-85 T 14-10-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 LH59_18630 3b02eab6821fb236923f7280f94ab324 315 Pfam PF04261 Dyp-type peroxidase family 9 305 4.2E-92 T 14-10-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 LH59_25885 65fbd358cfad6d2c10e6e3c99f93a87c 345 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 243 256 - T 14-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 LH59_25885 65fbd358cfad6d2c10e6e3c99f93a87c 345 Gene3D G3DSA:3.20.20.70 13 335 2.7E-120 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_25885 65fbd358cfad6d2c10e6e3c99f93a87c 345 Pfam PF00682 HMGL-like 33 313 6.8E-69 T 14-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 LH59_25885 65fbd358cfad6d2c10e6e3c99f93a87c 345 SUPERFAMILY SSF51569 22 328 8.06E-91 T 14-10-2018 LH59_06115 b2ede83bb60b4253b0d480bd5ce22748 208 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 1 177 33.28 T 14-10-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06115 b2ede83bb60b4253b0d480bd5ce22748 208 Gene3D G3DSA:3.30.460.80 1 149 1.8E-41 T 14-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06115 b2ede83bb60b4253b0d480bd5ce22748 208 SUPERFAMILY SSF143243 21 190 4.18E-51 T 14-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06115 b2ede83bb60b4253b0d480bd5ce22748 208 ProSitePatterns PS00542 Respiratory chain NADH dehydrogenase 30 Kd subunit signature. 130 151 - T 14-10-2018 IPR020396 NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06115 b2ede83bb60b4253b0d480bd5ce22748 208 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 96 157 5.0E-23 T 14-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06115 b2ede83bb60b4253b0d480bd5ce22748 208 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 32 170 9.8E-42 T 14-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06115 b2ede83bb60b4253b0d480bd5ce22748 208 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 31 168 2.8E-37 T 14-10-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_02560 ad4f42eb603de44132d5e8645aa6a486 277 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 45 262 3.1E-14 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_02560 ad4f42eb603de44132d5e8645aa6a486 277 Gene3D G3DSA:3.40.190.10 143 229 1.1E-11 T 14-10-2018 LH59_02560 ad4f42eb603de44132d5e8645aa6a486 277 Gene3D G3DSA:3.40.190.10 32 142 2.3E-13 T 14-10-2018 LH59_02560 ad4f42eb603de44132d5e8645aa6a486 277 SUPERFAMILY SSF53850 9 256 2.06E-22 T 14-10-2018 LH59_04065 d8fb57088023d947e14013487a399393 408 Hamap MF_02033 Cell division protein FtsA [ftsA]. 5 406 30.671 T 14-10-2018 IPR020823 Cell division protein FtsA LH59_04065 d8fb57088023d947e14013487a399393 408 Gene3D G3DSA:3.30.420.40 12 371 1.0E-122 T 14-10-2018 LH59_04065 d8fb57088023d947e14013487a399393 408 SUPERFAMILY SSF53067 198 375 2.32E-47 T 14-10-2018 LH59_04065 d8fb57088023d947e14013487a399393 408 PIRSF PIRSF003101 1 408 6.5E-151 T 14-10-2018 IPR020823 Cell division protein FtsA LH59_04065 d8fb57088023d947e14013487a399393 408 SMART SM00842 9 195 5.8E-107 T 14-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 LH59_04065 d8fb57088023d947e14013487a399393 408 Gene3D G3DSA:3.30.1490.110 86 168 1.0E-122 T 14-10-2018 LH59_04065 d8fb57088023d947e14013487a399393 408 SUPERFAMILY SSF53067 7 196 3.63E-63 T 14-10-2018 LH59_04065 d8fb57088023d947e14013487a399393 408 Gene3D G3DSA:3.90.640.10 234 299 1.0E-122 T 14-10-2018 LH59_04065 d8fb57088023d947e14013487a399393 408 Pfam PF14450 Cell division protein FtsA 206 373 3.5E-25 T 14-10-2018 LH59_04065 d8fb57088023d947e14013487a399393 408 Pfam PF14450 Cell division protein FtsA 10 193 5.6E-10 T 14-10-2018 LH59_04065 d8fb57088023d947e14013487a399393 408 Gene3D G3DSA:3.30.420.40 196 351 1.0E-122 T 14-10-2018 LH59_04065 d8fb57088023d947e14013487a399393 408 Pfam PF02491 SHS2 domain inserted in FTSA 84 161 1.9E-32 T 14-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 LH59_04065 d8fb57088023d947e14013487a399393 408 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 8 376 1.6E-147 T 14-10-2018 IPR020823 Cell division protein FtsA LH59_14940 003ed35e3f75fec4bdbc44054001fb1a 306 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 50 234 3.2E-31 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 LH59_14940 003ed35e3f75fec4bdbc44054001fb1a 306 Gene3D G3DSA:2.40.30.170 174 295 4.9E-27 T 14-10-2018 LH59_14940 003ed35e3f75fec4bdbc44054001fb1a 306 SUPERFAMILY SSF111369 44 227 1.96E-22 T 14-10-2018 LH59_14940 003ed35e3f75fec4bdbc44054001fb1a 306 Pfam PF13533 Biotin-lipoyl like 51 98 4.4E-18 T 14-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain LH59_14940 003ed35e3f75fec4bdbc44054001fb1a 306 Gene3D G3DSA:2.40.50.100 51 122 6.6E-13 T 14-10-2018 LH59_14940 003ed35e3f75fec4bdbc44054001fb1a 306 Pfam PF13437 HlyD family secretion protein 160 241 4.9E-9 T 14-10-2018 LH59_23475 a55e4ac7efcfa92f7de5196f8e9ac5e9 219 Gene3D G3DSA:2.60.120.590 18 219 4.2E-55 T 14-10-2018 IPR037151 Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily LH59_23475 a55e4ac7efcfa92f7de5196f8e9ac5e9 219 SUPERFAMILY SSF51197 26 217 2.06E-58 T 14-10-2018 LH59_23475 a55e4ac7efcfa92f7de5196f8e9ac5e9 219 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 39 216 5.9E-49 T 14-10-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like LH59_24665 99b05932aab6e2479c17966ad5376fee 207 Gene3D G3DSA:3.30.470.20 28 121 2.8E-6 T 14-10-2018 LH59_16110 3d86ee291c1eae7df3a2213f690b05ed 486 SUPERFAMILY SSF54631 94 201 7.44E-28 T 14-10-2018 LH59_16110 3d86ee291c1eae7df3a2213f690b05ed 486 SMART SM00116 156 204 2.6E-6 T 14-10-2018 IPR000644 CBS domain LH59_16110 3d86ee291c1eae7df3a2213f690b05ed 486 SMART SM00116 95 142 3.6E-11 T 14-10-2018 IPR000644 CBS domain LH59_16110 3d86ee291c1eae7df3a2213f690b05ed 486 SMART SM01240 6 472 0.0 T 14-10-2018 LH59_16110 3d86ee291c1eae7df3a2213f690b05ed 486 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 7 485 87.018 T 14-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 LH59_16110 3d86ee291c1eae7df3a2213f690b05ed 486 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 293 305 - T 14-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 LH59_16110 3d86ee291c1eae7df3a2213f690b05ed 486 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 7 472 7.2E-164 T 14-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 LH59_16110 3d86ee291c1eae7df3a2213f690b05ed 486 PIRSF PIRSF000130 1 486 5.7E-206 T 14-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 LH59_16110 3d86ee291c1eae7df3a2213f690b05ed 486 SUPERFAMILY SSF51412 2 476 1.31E-125 T 14-10-2018 LH59_16110 3d86ee291c1eae7df3a2213f690b05ed 486 Gene3D G3DSA:3.20.20.70 1 485 8.4E-216 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_16110 3d86ee291c1eae7df3a2213f690b05ed 486 Pfam PF00571 CBS domain 95 138 1.0E-9 T 14-10-2018 IPR000644 CBS domain LH59_16110 3d86ee291c1eae7df3a2213f690b05ed 486 Pfam PF00571 CBS domain 149 201 1.2E-4 T 14-10-2018 IPR000644 CBS domain LH59_16110 3d86ee291c1eae7df3a2213f690b05ed 486 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 7 453 7.3E-191 T 14-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 LH59_24790 9957c0e62b6fd842662c0d0c5810f2e3 546 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 230 262 0.0011 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_24790 9957c0e62b6fd842662c0d0c5810f2e3 546 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 500 526 3.1E-4 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_24790 9957c0e62b6fd842662c0d0c5810f2e3 546 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_24790 9957c0e62b6fd842662c0d0c5810f2e3 546 SMART SM00382 28 228 4.5E-19 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_24790 9957c0e62b6fd842662c0d0c5810f2e3 546 SMART SM00382 307 498 1.2E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_24790 9957c0e62b6fd842662c0d0c5810f2e3 546 SUPERFAMILY SSF52540 271 520 1.33E-72 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_24790 9957c0e62b6fd842662c0d0c5810f2e3 546 Pfam PF00005 ABC transporter 300 448 7.4E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_24790 9957c0e62b6fd842662c0d0c5810f2e3 546 ProSitePatterns PS00211 ABC transporters family signature. 421 435 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_24790 9957c0e62b6fd842662c0d0c5810f2e3 546 Gene3D G3DSA:3.40.50.300 271 544 8.0E-85 T 14-10-2018 LH59_24790 9957c0e62b6fd842662c0d0c5810f2e3 546 Gene3D G3DSA:3.40.50.300 1 270 1.7E-82 T 14-10-2018 LH59_24790 9957c0e62b6fd842662c0d0c5810f2e3 546 SUPERFAMILY SSF52540 5 250 1.02E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_24790 9957c0e62b6fd842662c0d0c5810f2e3 546 Pfam PF00005 ABC transporter 20 178 5.1E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_21045 fa285332ea923f8bf70004188d5f7900 427 Pfam PF02253 Phospholipase A1 209 425 3.7E-34 T 14-10-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 LH59_21045 fa285332ea923f8bf70004188d5f7900 427 Gene3D G3DSA:2.40.230.10 178 427 2.2E-51 T 14-10-2018 IPR036541 Phospholipase A1 superfamily GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 LH59_21045 fa285332ea923f8bf70004188d5f7900 427 SUPERFAMILY SSF56931 187 426 3.92E-54 T 14-10-2018 IPR036541 Phospholipase A1 superfamily GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 LH59_21045 fa285332ea923f8bf70004188d5f7900 427 PRINTS PR01486 Bacterial phospholipase A1 protein signature 337 355 6.6E-9 T 14-10-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 LH59_21045 fa285332ea923f8bf70004188d5f7900 427 PRINTS PR01486 Bacterial phospholipase A1 protein signature 285 299 6.6E-9 T 14-10-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 LH59_21045 fa285332ea923f8bf70004188d5f7900 427 PRINTS PR01486 Bacterial phospholipase A1 protein signature 207 224 6.6E-9 T 14-10-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 LH59_21045 fa285332ea923f8bf70004188d5f7900 427 PRINTS PR01486 Bacterial phospholipase A1 protein signature 397 417 6.6E-9 T 14-10-2018 IPR003187 Phospholipase A1 GO:0004620|GO:0006629|GO:0016020 KEGG: 00564+3.1.1.32+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.32+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 LH59_26745 016a88b6c78b944ee80fbce2f9da18e8 642 Pfam PF03717 Penicillin-binding Protein dimerisation domain 62 237 1.4E-41 T 14-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 LH59_26745 016a88b6c78b944ee80fbce2f9da18e8 642 Gene3D G3DSA:3.40.710.10 247 625 2.1E-99 T 14-10-2018 LH59_26745 016a88b6c78b944ee80fbce2f9da18e8 642 Hamap MF_02081 Peptidoglycan D,D-transpeptidase MrdA [mrdA]. 5 615 48.92 T 14-10-2018 IPR017790 Penicillin-binding protein 2 GO:0008658|GO:0009002|GO:0009252|GO:0016020 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 LH59_26745 016a88b6c78b944ee80fbce2f9da18e8 642 Gene3D G3DSA:3.30.1390.30 83 158 1.4E-42 T 14-10-2018 LH59_26745 016a88b6c78b944ee80fbce2f9da18e8 642 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 18 612 3.8E-225 T 14-10-2018 IPR017790 Penicillin-binding protein 2 GO:0008658|GO:0009002|GO:0009252|GO:0016020 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 LH59_26745 016a88b6c78b944ee80fbce2f9da18e8 642 Gene3D G3DSA:3.90.1310.10 62 246 1.4E-42 T 14-10-2018 LH59_26745 016a88b6c78b944ee80fbce2f9da18e8 642 Pfam PF00905 Penicillin binding protein transpeptidase domain 269 607 2.1E-65 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 LH59_26745 016a88b6c78b944ee80fbce2f9da18e8 642 SUPERFAMILY SSF56601 252 612 6.01E-100 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like LH59_26745 016a88b6c78b944ee80fbce2f9da18e8 642 SUPERFAMILY SSF56519 54 251 8.37E-47 T 14-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 LH59_21965 6707af887ecfa3e31787a38b0664233a 569 SUPERFAMILY SSF161098 297 555 6.73E-46 T 14-10-2018 IPR035906 MetI-like superfamily LH59_21965 6707af887ecfa3e31787a38b0664233a 569 Gene3D G3DSA:1.10.3720.10 286 548 5.4E-42 T 14-10-2018 IPR035906 MetI-like superfamily LH59_21965 6707af887ecfa3e31787a38b0664233a 569 Gene3D G3DSA:1.10.3720.10 13 279 4.6E-58 T 14-10-2018 IPR035906 MetI-like superfamily LH59_21965 6707af887ecfa3e31787a38b0664233a 569 SUPERFAMILY SSF161098 15 277 8.97E-50 T 14-10-2018 IPR035906 MetI-like superfamily LH59_21965 6707af887ecfa3e31787a38b0664233a 569 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 368 555 2.5E-15 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_21965 6707af887ecfa3e31787a38b0664233a 569 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 271 1.8E-11 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_01045 137f6025162ed811e2f6a65dfa004cc1 305 Gene3D G3DSA:3.40.190.10 92 290 2.0E-46 T 14-10-2018 LH59_01045 137f6025162ed811e2f6a65dfa004cc1 305 Pfam PF03466 LysR substrate binding domain 88 294 1.1E-43 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_01045 137f6025162ed811e2f6a65dfa004cc1 305 Gene3D G3DSA:3.40.190.10 163 268 2.0E-46 T 14-10-2018 LH59_01045 137f6025162ed811e2f6a65dfa004cc1 305 Gene3D G3DSA:1.10.10.10 2 89 1.3E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_01045 137f6025162ed811e2f6a65dfa004cc1 305 SUPERFAMILY SSF46785 2 112 6.45E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_01045 137f6025162ed811e2f6a65dfa004cc1 305 SUPERFAMILY SSF53850 90 296 4.62E-40 T 14-10-2018 LH59_01045 137f6025162ed811e2f6a65dfa004cc1 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 6.8E-20 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_01045 137f6025162ed811e2f6a65dfa004cc1 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.3E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_01045 137f6025162ed811e2f6a65dfa004cc1 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.3E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_01045 137f6025162ed811e2f6a65dfa004cc1 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.3E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_13330 0ca843761116ab9f17a4aa44ab358ad4 509 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 441 3.0E-137 T 14-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane LH59_15790 23faccf7b9df05abd5408b624e91cbf9 434 SUPERFAMILY SSF53335 65 251 1.5E-43 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_15790 23faccf7b9df05abd5408b624e91cbf9 434 Pfam PF13181 Tetratricopeptide repeat 366 399 8.8E-6 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 LH59_15790 23faccf7b9df05abd5408b624e91cbf9 434 PRINTS PR00996 Glutamate methyltransferase family signature 98 118 2.9E-20 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 LH59_15790 23faccf7b9df05abd5408b624e91cbf9 434 PRINTS PR00996 Glutamate methyltransferase family signature 58 70 2.9E-20 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 LH59_15790 23faccf7b9df05abd5408b624e91cbf9 434 PRINTS PR00996 Glutamate methyltransferase family signature 131 147 2.9E-20 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 LH59_15790 23faccf7b9df05abd5408b624e91cbf9 434 PRINTS PR00996 Glutamate methyltransferase family signature 219 242 2.9E-20 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 LH59_15790 23faccf7b9df05abd5408b624e91cbf9 434 PRINTS PR00996 Glutamate methyltransferase family signature 200 214 2.9E-20 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 LH59_15790 23faccf7b9df05abd5408b624e91cbf9 434 SMART SM00028 366 399 0.0039 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 LH59_15790 23faccf7b9df05abd5408b624e91cbf9 434 Pfam PF01739 CheR methyltransferase, SAM binding domain 66 241 2.8E-36 T 14-10-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal LH59_15790 23faccf7b9df05abd5408b624e91cbf9 434 SUPERFAMILY SSF48452 334 426 3.57E-11 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_15790 23faccf7b9df05abd5408b624e91cbf9 434 Gene3D G3DSA:3.40.50.150 64 252 4.9E-45 T 14-10-2018 LH59_15790 23faccf7b9df05abd5408b624e91cbf9 434 Gene3D G3DSA:1.25.40.10 324 431 7.6E-12 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_15790 23faccf7b9df05abd5408b624e91cbf9 434 SMART SM00138 3 260 1.9E-32 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 LH59_10475 93e552eb5a54737c5e475cb86c128fc5 445 Gene3D G3DSA:1.25.40.10 145 286 1.3E-27 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_10475 93e552eb5a54737c5e475cb86c128fc5 445 SMART SM00028 232 265 16.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 LH59_10475 93e552eb5a54737c5e475cb86c128fc5 445 SMART SM00028 161 194 3.6E-5 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 LH59_10475 93e552eb5a54737c5e475cb86c128fc5 445 TIGRFAM TIGR03142 cytochro_ccmI: cytochrome c-type biogenesis protein CcmI 4 121 2.3E-23 T 14-10-2018 IPR017560 Cytochrome c-type biogenesis protein CcmI LH59_10475 93e552eb5a54737c5e475cb86c128fc5 445 SUPERFAMILY SSF48452 157 297 1.52E-16 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_10475 93e552eb5a54737c5e475cb86c128fc5 445 Pfam PF07719 Tetratricopeptide repeat 161 192 2.7E-7 T 14-10-2018 IPR013105 Tetratricopeptide repeat 2 LH59_08440 831711d6b1cc5b92daa484de065359d7 459 Gene3D G3DSA:3.30.870.10 279 430 8.9E-33 T 14-10-2018 LH59_08440 831711d6b1cc5b92daa484de065359d7 459 SUPERFAMILY SSF56024 249 442 1.39E-45 T 14-10-2018 LH59_08440 831711d6b1cc5b92daa484de065359d7 459 Gene3D G3DSA:3.30.870.10 72 273 1.1E-43 T 14-10-2018 LH59_08440 831711d6b1cc5b92daa484de065359d7 459 SMART SM00155 372 399 1.2E-4 T 14-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 LH59_08440 831711d6b1cc5b92daa484de065359d7 459 SMART SM00155 176 203 0.0023 T 14-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 LH59_08440 831711d6b1cc5b92daa484de065359d7 459 Pfam PF13091 PLD-like domain 91 201 4.9E-14 T 14-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 LH59_08440 831711d6b1cc5b92daa484de065359d7 459 Pfam PF13091 PLD-like domain 300 426 6.2E-29 T 14-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 LH59_08440 831711d6b1cc5b92daa484de065359d7 459 SUPERFAMILY SSF56024 63 289 2.45E-48 T 14-10-2018 LH59_19755 124dfcf1e06cb581600c0d24c1bb1d1f 186 ProSitePatterns PS01275 Elongation factor P signature. 149 168 - T 14-10-2018 IPR013852 Translation elongation factor P/YeiP, conserved site LH59_19755 124dfcf1e06cb581600c0d24c1bb1d1f 186 Gene3D G3DSA:2.40.50.140 127 186 8.9E-29 T 14-10-2018 LH59_19755 124dfcf1e06cb581600c0d24c1bb1d1f 186 SMART SM00841 128 183 1.8E-27 T 14-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 LH59_19755 124dfcf1e06cb581600c0d24c1bb1d1f 186 SUPERFAMILY SSF50104 1 63 8.53E-15 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily LH59_19755 124dfcf1e06cb581600c0d24c1bb1d1f 186 Gene3D G3DSA:2.40.50.140 64 126 1.2E-21 T 14-10-2018 LH59_19755 124dfcf1e06cb581600c0d24c1bb1d1f 186 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 1.2E-16 T 14-10-2018 IPR013185 Translation elongation factor, KOW-like LH59_19755 124dfcf1e06cb581600c0d24c1bb1d1f 186 PIRSF PIRSF005901 1 185 4.6E-57 T 14-10-2018 IPR020599 Translation elongation factor P/YeiP LH59_19755 124dfcf1e06cb581600c0d24c1bb1d1f 186 Gene3D G3DSA:2.30.30.30 1 62 3.8E-17 T 14-10-2018 IPR014722 Ribosomal protein L2, domain 2 LH59_19755 124dfcf1e06cb581600c0d24c1bb1d1f 186 SUPERFAMILY SSF50249 65 126 1.76E-15 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_19755 124dfcf1e06cb581600c0d24c1bb1d1f 186 TIGRFAM TIGR00038 efp: translation elongation factor P 3 184 3.7E-64 T 14-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 LH59_19755 124dfcf1e06cb581600c0d24c1bb1d1f 186 SUPERFAMILY SSF50249 128 184 4.97E-17 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_19755 124dfcf1e06cb581600c0d24c1bb1d1f 186 Hamap MF_00141 Elongation factor P [efp]. 1 184 46.841 T 14-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 LH59_19755 124dfcf1e06cb581600c0d24c1bb1d1f 186 Pfam PF09285 Elongation factor P, C-terminal 128 183 3.1E-24 T 14-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 LH59_19755 124dfcf1e06cb581600c0d24c1bb1d1f 186 SMART SM01185 67 120 2.5E-20 T 14-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 LH59_19755 124dfcf1e06cb581600c0d24c1bb1d1f 186 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 120 3.3E-17 T 14-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 LH59_16045 cc5c70038ea1a13a45f028b2996bde5e 342 Gene3D G3DSA:3.20.20.210 1 342 5.4E-134 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 LH59_16045 cc5c70038ea1a13a45f028b2996bde5e 342 PIRSF PIRSF005632 1 342 4.4E-202 T 14-10-2018 IPR016456 Predicted cobalamin-independent methionine synthase, catalytic subunit LH59_16045 cc5c70038ea1a13a45f028b2996bde5e 342 SUPERFAMILY SSF51726 7 340 4.84E-67 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 LH59_16045 cc5c70038ea1a13a45f028b2996bde5e 342 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 5 327 1.3E-37 T 14-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 LH59_20915 68ecfbc6453743106b4587667545e03c 324 SUPERFAMILY SSF161098 89 306 4.97E-21 T 14-10-2018 IPR035906 MetI-like superfamily LH59_20915 68ecfbc6453743106b4587667545e03c 324 Gene3D G3DSA:1.10.3720.10 83 315 1.9E-26 T 14-10-2018 IPR035906 MetI-like superfamily LH59_20915 68ecfbc6453743106b4587667545e03c 324 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 319 4.9E-41 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_14035 d92034a7259da175f46f54df034d7e54 152 SUPERFAMILY SSF49503 25 149 5.54E-33 T 14-10-2018 IPR008972 Cupredoxin LH59_14035 d92034a7259da175f46f54df034d7e54 152 TIGRFAM TIGR02695 azurin: azurin 25 149 2.2E-44 T 14-10-2018 IPR014068 Azurin LH59_14035 d92034a7259da175f46f54df034d7e54 152 ProDom PD003655 COPPER ELECTRON AZURIN METAL-BINDING PERIPLASMIC PRECURSOR SIGNAL SEQUENCING DIRECT MEMBRANE 27 149 2.0E-30 T 14-10-2018 LH59_14035 d92034a7259da175f46f54df034d7e54 152 ProSitePatterns PS00196 Type-1 copper (blue) proteins signature. 127 143 - T 14-10-2018 IPR028871 Blue (type 1) copper protein, binding site LH59_14035 d92034a7259da175f46f54df034d7e54 152 Pfam PF00127 Copper binding proteins, plastocyanin/azurin family 25 149 5.4E-18 T 14-10-2018 IPR000923 Blue (type 1) copper domain GO:0005507|GO:0009055 LH59_14035 d92034a7259da175f46f54df034d7e54 152 Gene3D G3DSA:2.60.40.420 23 150 8.3E-35 T 14-10-2018 IPR008972 Cupredoxin LH59_06555 b44db860e5702a373c2ff1cddef3d531 253 Pfam PF00035 Double-stranded RNA binding motif 153 218 4.3E-9 T 14-10-2018 IPR014720 Double-stranded RNA-binding domain LH59_06555 b44db860e5702a373c2ff1cddef3d531 253 Pfam PF14622 Ribonuclease-III-like 16 137 4.7E-38 T 14-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 LH59_06555 b44db860e5702a373c2ff1cddef3d531 253 ProSitePatterns PS00517 Ribonuclease III family signature. 35 43 - T 14-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 LH59_06555 b44db860e5702a373c2ff1cddef3d531 253 SMART SM00358 153 221 1.5E-13 T 14-10-2018 IPR014720 Double-stranded RNA-binding domain LH59_06555 b44db860e5702a373c2ff1cddef3d531 253 Hamap MF_00104 Ribonuclease 3 [rnc]. 6 217 29.308 T 14-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 LH59_06555 b44db860e5702a373c2ff1cddef3d531 253 Gene3D G3DSA:1.10.1520.10 2 142 1.4E-45 T 14-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 LH59_06555 b44db860e5702a373c2ff1cddef3d531 253 SUPERFAMILY SSF69065 2 152 2.27E-48 T 14-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 LH59_06555 b44db860e5702a373c2ff1cddef3d531 253 SMART SM00535 18 146 3.8E-53 T 14-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 LH59_06555 b44db860e5702a373c2ff1cddef3d531 253 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 6 219 1.1E-69 T 14-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 LH59_06555 b44db860e5702a373c2ff1cddef3d531 253 SUPERFAMILY SSF54768 106 225 9.27E-23 T 14-10-2018 LH59_06555 b44db860e5702a373c2ff1cddef3d531 253 Gene3D G3DSA:3.30.160.20 151 221 2.9E-15 T 14-10-2018 LH59_25070 29c3b24ca95f5f083a8dfb44ca5941bf 450 SUPERFAMILY SSF46626 191 303 4.22E-16 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_25070 29c3b24ca95f5f083a8dfb44ca5941bf 450 Gene3D G3DSA:1.10.760.10 7 153 4.4E-10 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_25070 29c3b24ca95f5f083a8dfb44ca5941bf 450 Pfam PF00034 Cytochrome c 47 147 3.0E-6 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_25070 29c3b24ca95f5f083a8dfb44ca5941bf 450 Pfam PF00034 Cytochrome c 332 416 8.1E-9 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_25070 29c3b24ca95f5f083a8dfb44ca5941bf 450 SUPERFAMILY SSF46626 42 171 8.47E-20 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_25070 29c3b24ca95f5f083a8dfb44ca5941bf 450 PIRSF PIRSF000018 22 445 1.9E-143 T 14-10-2018 IPR014353 Membrane-bound alcohol dehydrogenase, cytochrome c subunit GO:0005506|GO:0016020|GO:0016614|GO:0020037 LH59_25070 29c3b24ca95f5f083a8dfb44ca5941bf 450 Gene3D G3DSA:1.10.760.10 170 306 1.2E-6 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_25070 29c3b24ca95f5f083a8dfb44ca5941bf 450 SUPERFAMILY SSF46626 332 433 6.88E-23 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_25070 29c3b24ca95f5f083a8dfb44ca5941bf 450 Gene3D G3DSA:1.10.760.10 311 441 1.9E-30 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_16105 49284578c00fa94ed2214a956f2c1ea0 530 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 211 530 8.7E-143 T 14-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 LH59_16105 49284578c00fa94ed2214a956f2c1ea0 530 SUPERFAMILY SSF52317 1 235 6.23E-56 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_16105 49284578c00fa94ed2214a956f2c1ea0 530 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 2 530 54.529 T 14-10-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 LH59_16105 49284578c00fa94ed2214a956f2c1ea0 530 Gene3D G3DSA:3.30.300.10 404 530 2.9E-50 T 14-10-2018 LH59_16105 49284578c00fa94ed2214a956f2c1ea0 530 SUPERFAMILY SSF52402 195 415 9.04E-56 T 14-10-2018 LH59_16105 49284578c00fa94ed2214a956f2c1ea0 530 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 5 202 1.1E-69 T 14-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 LH59_16105 49284578c00fa94ed2214a956f2c1ea0 530 Pfam PF00117 Glutamine amidotransferase class-I 7 196 2.6E-35 T 14-10-2018 IPR017926 Glutamine amidotransferase LH59_16105 49284578c00fa94ed2214a956f2c1ea0 530 Gene3D G3DSA:3.40.50.880 4 204 3.7E-53 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_16105 49284578c00fa94ed2214a956f2c1ea0 530 Pfam PF02540 NAD synthase 221 289 2.0E-8 T 14-10-2018 IPR022310 NAD/GMP synthase LH59_16105 49284578c00fa94ed2214a956f2c1ea0 530 SUPERFAMILY SSF54810 403 530 1.57E-46 T 14-10-2018 LH59_16105 49284578c00fa94ed2214a956f2c1ea0 530 Pfam PF00958 GMP synthase C terminal domain 444 529 1.8E-41 T 14-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 LH59_16105 49284578c00fa94ed2214a956f2c1ea0 530 Gene3D G3DSA:3.40.50.620 207 403 3.7E-74 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LH59_14880 8c8273b701ea0f9caf78c004ad3f05fa 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 294 6.3E-27 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_14880 8c8273b701ea0f9caf78c004ad3f05fa 300 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 25 66 1.3E-7 T 14-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain LH59_14880 8c8273b701ea0f9caf78c004ad3f05fa 300 Gene3D G3DSA:1.10.3720.10 86 291 2.7E-21 T 14-10-2018 IPR035906 MetI-like superfamily LH59_14880 8c8273b701ea0f9caf78c004ad3f05fa 300 SUPERFAMILY SSF161098 91 276 6.8E-26 T 14-10-2018 IPR035906 MetI-like superfamily LH59_08155 00897679763261cb997fc381b4be0c93 486 Gene3D G3DSA:3.30.2290.10 19 240 1.9E-18 T 14-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal LH59_08155 00897679763261cb997fc381b4be0c93 486 Pfam PF01523 Putative modulator of DNA gyrase 43 337 1.2E-67 T 14-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 LH59_08155 00897679763261cb997fc381b4be0c93 486 PIRSF PIRSF004919 23 486 2.2E-135 T 14-10-2018 IPR025502 TldD LH59_08155 00897679763261cb997fc381b4be0c93 486 SUPERFAMILY SSF111283 28 485 5.1E-132 T 14-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 LH59_13090 410e94b4a27f62f1cf36efd305ece3f0 411 SUPERFAMILY SSF54373 270 355 5.1E-6 T 14-10-2018 LH59_13090 410e94b4a27f62f1cf36efd305ece3f0 411 Gene3D G3DSA:3.50.50.60 4 51 3.9E-12 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_13090 410e94b4a27f62f1cf36efd305ece3f0 411 Gene3D G3DSA:3.50.50.60 106 402 4.5E-43 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_13090 410e94b4a27f62f1cf36efd305ece3f0 411 SUPERFAMILY SSF51905 3 411 1.81E-43 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_13090 410e94b4a27f62f1cf36efd305ece3f0 411 Pfam PF01266 FAD dependent oxidoreductase 4 392 1.6E-56 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 LH59_13090 410e94b4a27f62f1cf36efd305ece3f0 411 Gene3D G3DSA:3.30.9.10 135 357 4.5E-43 T 14-10-2018 LH59_16580 47d178215074f4525475f5151984dab0 328 Gene3D G3DSA:3.40.190.150 31 317 8.7E-108 T 14-10-2018 LH59_16580 47d178215074f4525475f5151984dab0 328 Gene3D G3DSA:3.40.190.10 129 252 8.7E-108 T 14-10-2018 LH59_16580 47d178215074f4525475f5151984dab0 328 PIRSF PIRSF017082 1 326 2.8E-78 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_16580 47d178215074f4525475f5151984dab0 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 321 4.8E-79 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_16580 47d178215074f4525475f5151984dab0 328 SUPERFAMILY SSF53850 112 288 4.78E-8 T 14-10-2018 LH59_10810 98883e2e3f198d89fb9c0c42e81d0fde 321 Gene3D G3DSA:1.10.10.10 10 101 2.3E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_10810 98883e2e3f198d89fb9c0c42e81d0fde 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 37 47 4.1E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_10810 98883e2e3f198d89fb9c0c42e81d0fde 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 26 37 4.1E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_10810 98883e2e3f198d89fb9c0c42e81d0fde 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 47 58 4.1E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_10810 98883e2e3f198d89fb9c0c42e81d0fde 321 Gene3D G3DSA:3.40.190.10 111 304 3.2E-34 T 14-10-2018 LH59_10810 98883e2e3f198d89fb9c0c42e81d0fde 321 Pfam PF03466 LysR substrate binding domain 100 307 1.7E-24 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_10810 98883e2e3f198d89fb9c0c42e81d0fde 321 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 71 1.3E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_10810 98883e2e3f198d89fb9c0c42e81d0fde 321 Gene3D G3DSA:3.40.190.10 175 276 3.2E-34 T 14-10-2018 LH59_10810 98883e2e3f198d89fb9c0c42e81d0fde 321 SUPERFAMILY SSF53850 102 309 9.0E-27 T 14-10-2018 LH59_10810 98883e2e3f198d89fb9c0c42e81d0fde 321 SUPERFAMILY SSF46785 7 92 1.27E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_16675 f6d17dc79300dd1ca58b14b191aa86a7 307 Gene3D G3DSA:3.30.1150.10 14 122 6.4E-21 T 14-10-2018 LH59_16675 f6d17dc79300dd1ca58b14b191aa86a7 307 Pfam PF13103 TonB C terminal 30 105 1.7E-11 T 14-10-2018 LH59_16675 f6d17dc79300dd1ca58b14b191aa86a7 307 SUPERFAMILY SSF74653 25 119 6.93E-19 T 14-10-2018 LH59_16675 f6d17dc79300dd1ca58b14b191aa86a7 307 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 47 119 5.4E-11 T 14-10-2018 IPR006260 TonB/TolA, C-terminal LH59_15160 b0a643bee9fc03cf83081a9efd40003b 279 Pfam PF09339 IclR helix-turn-helix domain 33 78 5.2E-13 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_15160 b0a643bee9fc03cf83081a9efd40003b 279 SUPERFAMILY SSF46785 32 101 1.16E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_15160 b0a643bee9fc03cf83081a9efd40003b 279 Gene3D G3DSA:3.30.450.40 103 276 1.6E-51 T 14-10-2018 IPR029016 GAF-like domain superfamily LH59_15160 b0a643bee9fc03cf83081a9efd40003b 279 SMART SM00346 29 118 7.6E-6 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_15160 b0a643bee9fc03cf83081a9efd40003b 279 Pfam PF01614 Bacterial transcriptional regulator 150 269 3.8E-30 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal LH59_15160 b0a643bee9fc03cf83081a9efd40003b 279 Gene3D G3DSA:1.10.10.10 31 101 3.5E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_15160 b0a643bee9fc03cf83081a9efd40003b 279 SUPERFAMILY SSF55781 103 272 6.38E-47 T 14-10-2018 LH59_18850 16f90f3880011d1cfd3991ab5c46df02 307 SMART SM00382 30 211 1.8E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_18850 16f90f3880011d1cfd3991ab5c46df02 307 Pfam PF00005 ABC transporter 21 163 2.2E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_18850 16f90f3880011d1cfd3991ab5c46df02 307 SUPERFAMILY SSF52540 2 229 2.41E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_18850 16f90f3880011d1cfd3991ab5c46df02 307 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_18850 16f90f3880011d1cfd3991ab5c46df02 307 Gene3D G3DSA:3.40.50.300 1 234 1.2E-64 T 14-10-2018 LH59_17310 4df450666126e11ebb3b436962719bf7 193 SUPERFAMILY SSF46689 3 87 7.7E-21 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_17310 4df450666126e11ebb3b436962719bf7 193 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 59 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site LH59_17310 4df450666126e11ebb3b436962719bf7 193 SUPERFAMILY SSF48498 83 191 2.39E-6 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily LH59_17310 4df450666126e11ebb3b436962719bf7 193 Gene3D G3DSA:1.10.357.10 1 192 6.0E-61 T 14-10-2018 LH59_17310 4df450666126e11ebb3b436962719bf7 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 5.2E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_17310 4df450666126e11ebb3b436962719bf7 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 5.2E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_17310 4df450666126e11ebb3b436962719bf7 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 4.0E-16 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_00485 e22c0550a7642cad0c76bdf8f4b1a699 323 Pfam PF16220 Domain of unknown function (DUF4880) 2 35 3.4E-6 T 14-10-2018 IPR032623 FecR, N-terminal LH59_00485 e22c0550a7642cad0c76bdf8f4b1a699 323 Gene3D G3DSA:2.60.120.1440 103 239 2.0E-12 T 14-10-2018 LH59_00485 e22c0550a7642cad0c76bdf8f4b1a699 323 Pfam PF04773 FecR protein 117 204 1.5E-10 T 14-10-2018 IPR006860 FecR protein LH59_00485 e22c0550a7642cad0c76bdf8f4b1a699 323 PIRSF PIRSF018266 1 323 4.7E-58 T 14-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component LH59_21420 64aa285f33961686bca46cd4b8f9f1c3 124 Gene3D G3DSA:3.30.429.10 65 124 1.9E-13 T 14-10-2018 IPR014347 Tautomerase/MIF superfamily LH59_21420 64aa285f33961686bca46cd4b8f9f1c3 124 Gene3D G3DSA:3.30.429.10 1 64 9.4E-17 T 14-10-2018 IPR014347 Tautomerase/MIF superfamily LH59_21420 64aa285f33961686bca46cd4b8f9f1c3 124 SUPERFAMILY SSF55331 2 118 3.0E-24 T 14-10-2018 IPR014347 Tautomerase/MIF superfamily LH59_21420 64aa285f33961686bca46cd4b8f9f1c3 124 Pfam PF01361 Tautomerase enzyme 2 56 8.5E-12 T 14-10-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 LH59_21420 64aa285f33961686bca46cd4b8f9f1c3 124 Pfam PF01361 Tautomerase enzyme 68 114 3.9E-8 T 14-10-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 LH59_21920 ff99b0e7c5783fefb64e6634cd2e1080 281 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 53 66 - T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LH59_21920 ff99b0e7c5783fefb64e6634cd2e1080 281 Pfam PF00809 Pterin binding enzyme 20 259 2.1E-83 T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LH59_21920 ff99b0e7c5783fefb64e6634cd2e1080 281 SUPERFAMILY SSF51717 6 274 5.36E-99 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LH59_21920 ff99b0e7c5783fefb64e6634cd2e1080 281 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 19 273 7.4E-99 T 14-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 LH59_21920 ff99b0e7c5783fefb64e6634cd2e1080 281 Gene3D G3DSA:3.20.20.20 1 279 1.3E-109 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LH59_21920 ff99b0e7c5783fefb64e6634cd2e1080 281 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 19 34 - T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LH59_08900 574f409a69c2dd9ad906ab7525d4eca5 419 Gene3D G3DSA:1.10.287.470 87 110 4.0E-11 T 14-10-2018 LH59_08900 574f409a69c2dd9ad906ab7525d4eca5 419 Pfam PF13437 HlyD family secretion protein 224 344 8.2E-15 T 14-10-2018 LH59_08900 574f409a69c2dd9ad906ab7525d4eca5 419 Gene3D G3DSA:2.40.50.100 54 86 4.0E-11 T 14-10-2018 LH59_08900 574f409a69c2dd9ad906ab7525d4eca5 419 SUPERFAMILY SSF111369 172 275 2.62E-8 T 14-10-2018 LH59_08900 574f409a69c2dd9ad906ab7525d4eca5 419 SUPERFAMILY SSF111369 124 182 5.62E-5 T 14-10-2018 LH59_08900 574f409a69c2dd9ad906ab7525d4eca5 419 Gene3D G3DSA:2.40.30.170 239 359 2.6E-34 T 14-10-2018 LH59_08900 574f409a69c2dd9ad906ab7525d4eca5 419 Pfam PF13533 Biotin-lipoyl like 54 101 9.0E-12 T 14-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain LH59_08900 574f409a69c2dd9ad906ab7525d4eca5 419 SUPERFAMILY SSF111369 52 108 2.75E-7 T 14-10-2018 LH59_08900 574f409a69c2dd9ad906ab7525d4eca5 419 Gene3D G3DSA:1.10.287.470 120 188 1.8E-9 T 14-10-2018 LH59_00310 f047516ddb86cf2c7878f17e9ea21f19 603 Gene3D G3DSA:3.40.50.970 16 195 1.4E-66 T 14-10-2018 LH59_00310 f047516ddb86cf2c7878f17e9ea21f19 603 SUPERFAMILY SSF52518 19 185 2.94E-59 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold LH59_00310 f047516ddb86cf2c7878f17e9ea21f19 603 Gene3D G3DSA:3.40.50.970 392 600 5.5E-74 T 14-10-2018 LH59_00310 f047516ddb86cf2c7878f17e9ea21f19 603 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 22 592 4.6E-213 T 14-10-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 LH59_00310 f047516ddb86cf2c7878f17e9ea21f19 603 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 223 360 2.5E-41 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 LH59_00310 f047516ddb86cf2c7878f17e9ea21f19 603 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 458 477 - T 14-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 LH59_00310 f047516ddb86cf2c7878f17e9ea21f19 603 SUPERFAMILY SSF52518 399 594 1.34E-69 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold LH59_00310 f047516ddb86cf2c7878f17e9ea21f19 603 SUPERFAMILY SSF52467 217 386 6.74E-56 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily LH59_00310 f047516ddb86cf2c7878f17e9ea21f19 603 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 421 569 2.7E-53 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 LH59_00310 f047516ddb86cf2c7878f17e9ea21f19 603 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 22 185 6.5E-57 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 LH59_00310 f047516ddb86cf2c7878f17e9ea21f19 603 Gene3D G3DSA:3.40.50.1220 217 386 1.1E-55 T 14-10-2018 LH59_25485 05cfa1ee6500d450f165f5748b66e836 436 Gene3D G3DSA:1.20.1250.20 239 433 1.7E-26 T 14-10-2018 LH59_25485 05cfa1ee6500d450f165f5748b66e836 436 TIGRFAM TIGR00893 2A0114: D-galactonate transporter 28 428 6.1E-126 T 14-10-2018 LH59_25485 05cfa1ee6500d450f165f5748b66e836 436 PIRSF PIRSF002808 4 436 1.8E-38 T 14-10-2018 IPR000849 Sugar phosphate transporter GO:0016021|GO:0022857|GO:0055085 LH59_25485 05cfa1ee6500d450f165f5748b66e836 436 Pfam PF07690 Major Facilitator Superfamily 26 391 4.0E-57 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_25485 05cfa1ee6500d450f165f5748b66e836 436 Gene3D G3DSA:1.20.1250.20 12 207 6.6E-50 T 14-10-2018 LH59_25485 05cfa1ee6500d450f165f5748b66e836 436 SUPERFAMILY SSF103473 12 429 1.29E-81 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_26360 71a45f4c551ef2340d1c7e191a6f123b 481 Gene3D G3DSA:3.30.750.44 47 353 4.8E-88 T 14-10-2018 LH59_26360 71a45f4c551ef2340d1c7e191a6f123b 481 Pfam PF03572 Peptidase family S41 199 377 7.2E-52 T 14-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 LH59_26360 71a45f4c551ef2340d1c7e191a6f123b 481 SMART SM00245 173 378 4.4E-59 T 14-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 LH59_26360 71a45f4c551ef2340d1c7e191a6f123b 481 Pfam PF13180 PDZ domain 100 176 4.0E-10 T 14-10-2018 IPR001478 PDZ domain GO:0005515 LH59_26360 71a45f4c551ef2340d1c7e191a6f123b 481 SUPERFAMILY SSF52096 39 386 2.15E-75 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily LH59_26360 71a45f4c551ef2340d1c7e191a6f123b 481 SMART SM00228 100 171 3.7E-17 T 14-10-2018 IPR001478 PDZ domain GO:0005515 LH59_26360 71a45f4c551ef2340d1c7e191a6f123b 481 Gene3D G3DSA:2.30.42.10 100 187 4.8E-88 T 14-10-2018 LH59_26360 71a45f4c551ef2340d1c7e191a6f123b 481 SUPERFAMILY SSF50156 89 183 5.11E-20 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 LH59_26360 71a45f4c551ef2340d1c7e191a6f123b 481 Gene3D G3DSA:3.90.226.10 188 375 4.8E-88 T 14-10-2018 LH59_26360 71a45f4c551ef2340d1c7e191a6f123b 481 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 52 380 1.4E-94 T 14-10-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 LH59_09960 dd6468e4a848ef54581823422c3996bc 153 Gene3D G3DSA:1.10.1510.10 4 93 2.1E-26 T 14-10-2018 LH59_09960 dd6468e4a848ef54581823422c3996bc 153 Pfam PF09424 Yqey-like protein 7 152 1.7E-48 T 14-10-2018 IPR019004 Uncharacterised protein YqeY/AIM41 LH59_09960 dd6468e4a848ef54581823422c3996bc 153 Gene3D G3DSA:1.10.10.410 94 153 9.5E-11 T 14-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal LH59_09960 dd6468e4a848ef54581823422c3996bc 153 SUPERFAMILY SSF89095 5 152 2.41E-35 T 14-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 LH59_23235 cf32742fa72f0f307805094bed474cf1 306 SUPERFAMILY SSF46785 1 113 2.18E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_23235 cf32742fa72f0f307805094bed474cf1 306 Gene3D G3DSA:1.10.10.10 3 91 1.2E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_23235 cf32742fa72f0f307805094bed474cf1 306 Pfam PF03466 LysR substrate binding domain 89 294 3.6E-36 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_23235 cf32742fa72f0f307805094bed474cf1 306 Gene3D G3DSA:3.40.190.290 93 300 3.4E-38 T 14-10-2018 LH59_23235 cf32742fa72f0f307805094bed474cf1 306 SUPERFAMILY SSF53850 90 298 7.25E-42 T 14-10-2018 LH59_23235 cf32742fa72f0f307805094bed474cf1 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 7.1E-16 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_15130 360c4de439f381a095b5bb08d02e2fac 481 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 14 424 9.7E-69 T 14-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 LH59_15130 360c4de439f381a095b5bb08d02e2fac 481 SUPERFAMILY SSF103473 7 466 1.1E-61 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_15130 360c4de439f381a095b5bb08d02e2fac 481 Pfam PF07690 Major Facilitator Superfamily 17 412 2.5E-45 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_15130 360c4de439f381a095b5bb08d02e2fac 481 Gene3D G3DSA:1.20.1250.20 260 470 1.3E-16 T 14-10-2018 LH59_15130 360c4de439f381a095b5bb08d02e2fac 481 Gene3D G3DSA:1.20.1720.10 13 223 8.6E-50 T 14-10-2018 LH59_23710 8d598136e89bc25b31044a6bd7d5e1cb 347 SUPERFAMILY SSF49503 128 286 3.37E-50 T 14-10-2018 IPR008972 Cupredoxin LH59_23710 8d598136e89bc25b31044a6bd7d5e1cb 347 TIGRFAM TIGR01433 CyoA: ubiquinol oxidase, subunit II 11 243 1.1E-107 T 14-10-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 LH59_23710 8d598136e89bc25b31044a6bd7d5e1cb 347 Pfam PF06481 COX Aromatic Rich Motif 244 289 5.5E-21 T 14-10-2018 IPR010514 COX aromatic rich motif GO:0008827|GO:0016021|GO:0022900|GO:0055114 LH59_23710 8d598136e89bc25b31044a6bd7d5e1cb 347 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 157 224 2.5E-6 T 14-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_23710 8d598136e89bc25b31044a6bd7d5e1cb 347 SUPERFAMILY SSF81464 26 114 6.21E-23 T 14-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_23710 8d598136e89bc25b31044a6bd7d5e1cb 347 Gene3D G3DSA:1.10.287.90 24 109 1.0E-30 T 14-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_23710 8d598136e89bc25b31044a6bd7d5e1cb 347 PIRSF PIRSF000292 3 313 2.0E-125 T 14-10-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 LH59_23710 8d598136e89bc25b31044a6bd7d5e1cb 347 Gene3D G3DSA:2.60.40.420 110 286 3.7E-52 T 14-10-2018 IPR008972 Cupredoxin LH59_11080 f757521263d9dfc713bb8a8860fcb17d 204 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 11 33 3.3E-7 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site LH59_11080 f757521263d9dfc713bb8a8860fcb17d 204 SUPERFAMILY SSF54523 54 201 7.46E-12 T 14-10-2018 LH59_11080 f757521263d9dfc713bb8a8860fcb17d 204 Pfam PF11612 Type II secretion system (T2SS), protein J 64 197 6.6E-8 T 14-10-2018 IPR010055 Type II secretion system protein J GO:0008565|GO:0015627|GO:0015628 LH59_11080 f757521263d9dfc713bb8a8860fcb17d 204 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 12 32 - T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site LH59_11080 f757521263d9dfc713bb8a8860fcb17d 204 Pfam PF07963 Prokaryotic N-terminal methylation motif 10 33 2.8E-9 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site LH59_19000 e3ab968caf4604da2f6c9294f1f22a07 211 SUPERFAMILY SSF52833 13 93 1.47E-15 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_19000 e3ab968caf4604da2f6c9294f1f22a07 211 Pfam PF13409 Glutathione S-transferase, N-terminal domain 21 84 6.4E-8 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 LH59_19000 e3ab968caf4604da2f6c9294f1f22a07 211 SUPERFAMILY SSF47616 85 209 4.5E-30 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily LH59_19000 e3ab968caf4604da2f6c9294f1f22a07 211 Pfam PF00043 Glutathione S-transferase, C-terminal domain 140 202 5.4E-12 T 14-10-2018 IPR004046 Glutathione S-transferase, C-terminal LH59_19000 e3ab968caf4604da2f6c9294f1f22a07 211 Gene3D G3DSA:1.20.1050.10 91 205 1.1E-36 T 14-10-2018 LH59_19000 e3ab968caf4604da2f6c9294f1f22a07 211 Gene3D G3DSA:3.40.30.10 12 89 3.4E-14 T 14-10-2018 LH59_02710 c32d790d3ba937eb39be139838952525 334 Gene3D G3DSA:3.40.190.10 136 259 1.8E-96 T 14-10-2018 LH59_02710 c32d790d3ba937eb39be139838952525 334 SUPERFAMILY SSF53850 129 297 4.4E-13 T 14-10-2018 LH59_02710 c32d790d3ba937eb39be139838952525 334 PIRSF PIRSF017082 1 334 2.4E-71 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_02710 c32d790d3ba937eb39be139838952525 334 Gene3D G3DSA:3.40.190.150 38 324 1.8E-96 T 14-10-2018 LH59_02710 c32d790d3ba937eb39be139838952525 334 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 57 331 3.9E-74 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_25565 5cb9eb7f42b4c67636515dfb0be89719 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 5.1E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25565 5cb9eb7f42b4c67636515dfb0be89719 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 5.1E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25565 5cb9eb7f42b4c67636515dfb0be89719 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 5.1E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25565 5cb9eb7f42b4c67636515dfb0be89719 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 247 1.1E-54 T 14-10-2018 LH59_25565 5cb9eb7f42b4c67636515dfb0be89719 259 Gene3D G3DSA:3.40.50.720 1 252 1.1E-67 T 14-10-2018 LH59_25565 5cb9eb7f42b4c67636515dfb0be89719 259 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 135 163 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LH59_25565 5cb9eb7f42b4c67636515dfb0be89719 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 8.7E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25565 5cb9eb7f42b4c67636515dfb0be89719 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 8.7E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25565 5cb9eb7f42b4c67636515dfb0be89719 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 8.7E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25565 5cb9eb7f42b4c67636515dfb0be89719 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 8.7E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25565 5cb9eb7f42b4c67636515dfb0be89719 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 8.7E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25565 5cb9eb7f42b4c67636515dfb0be89719 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 8.7E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25565 5cb9eb7f42b4c67636515dfb0be89719 259 SUPERFAMILY SSF51735 7 247 7.77E-69 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_06980 40deb63087e30d8253aa821baafa2161 475 SUPERFAMILY SSF55424 352 473 5.5E-42 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 LH59_06980 40deb63087e30d8253aa821baafa2161 475 PIRSF PIRSF000350 1 474 9.2E-82 T 14-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 LH59_06980 40deb63087e30d8253aa821baafa2161 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 352 373 1.4E-75 T 14-10-2018 LH59_06980 40deb63087e30d8253aa821baafa2161 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 149 158 1.4E-75 T 14-10-2018 LH59_06980 40deb63087e30d8253aa821baafa2161 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 317 324 1.4E-75 T 14-10-2018 LH59_06980 40deb63087e30d8253aa821baafa2161 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 45 60 1.4E-75 T 14-10-2018 LH59_06980 40deb63087e30d8253aa821baafa2161 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 439 459 1.4E-75 T 14-10-2018 LH59_06980 40deb63087e30d8253aa821baafa2161 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 1.4E-75 T 14-10-2018 LH59_06980 40deb63087e30d8253aa821baafa2161 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 274 288 1.4E-75 T 14-10-2018 LH59_06980 40deb63087e30d8253aa821baafa2161 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 185 210 1.4E-75 T 14-10-2018 LH59_06980 40deb63087e30d8253aa821baafa2161 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 417 432 1.4E-75 T 14-10-2018 LH59_06980 40deb63087e30d8253aa821baafa2161 475 SUPERFAMILY SSF51905 1 347 6.16E-61 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_06980 40deb63087e30d8253aa821baafa2161 475 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 356 465 1.8E-38 T 14-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 LH59_06980 40deb63087e30d8253aa821baafa2161 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 4.4E-40 T 14-10-2018 LH59_06980 40deb63087e30d8253aa821baafa2161 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 4.4E-40 T 14-10-2018 LH59_06980 40deb63087e30d8253aa821baafa2161 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 185 203 4.4E-40 T 14-10-2018 LH59_06980 40deb63087e30d8253aa821baafa2161 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 273 289 4.4E-40 T 14-10-2018 LH59_06980 40deb63087e30d8253aa821baafa2161 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 302 324 4.4E-40 T 14-10-2018 LH59_06980 40deb63087e30d8253aa821baafa2161 475 Gene3D G3DSA:3.50.50.60 5 344 6.9E-109 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_06980 40deb63087e30d8253aa821baafa2161 475 Gene3D G3DSA:3.50.50.60 164 286 6.9E-109 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_06980 40deb63087e30d8253aa821baafa2161 475 Gene3D G3DSA:3.30.390.30 355 475 1.7E-46 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 LH59_06980 40deb63087e30d8253aa821baafa2161 475 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 474 4.7E-160 T 14-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 LH59_06980 40deb63087e30d8253aa821baafa2161 475 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 337 6.3E-68 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LH59_16565 ecd856a965e8986ba085de4436543d1f 490 Gene3D G3DSA:3.40.630.10 13 245 8.5E-53 T 14-10-2018 LH59_16565 ecd856a965e8986ba085de4436543d1f 490 Gene3D G3DSA:3.40.630.10 358 490 3.3E-22 T 14-10-2018 LH59_16565 ecd856a965e8986ba085de4436543d1f 490 Pfam PF01546 Peptidase family M20/M25/M40 107 484 2.0E-22 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 LH59_16565 ecd856a965e8986ba085de4436543d1f 490 SUPERFAMILY SSF53187 25 485 1.53E-44 T 14-10-2018 LH59_16565 ecd856a965e8986ba085de4436543d1f 490 Pfam PF07687 Peptidase dimerisation domain 219 383 1.1E-13 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain LH59_07985 be943456d11e117800d3f7750d4c161f 1324 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 42 430 3.7E-114 T 14-10-2018 IPR010071 Amino acid adenylation domain LH59_07985 be943456d11e117800d3f7750d4c161f 1324 Pfam PF13193 AMP-binding enzyme C-terminal domain 414 488 2.2E-10 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain LH59_07985 be943456d11e117800d3f7750d4c161f 1324 Gene3D G3DSA:3.40.50.12780 12 398 1.2E-114 T 14-10-2018 LH59_07985 be943456d11e117800d3f7750d4c161f 1324 TIGRFAM TIGR02353 NRPS_term_dom: non-ribosomal peptide synthetase terminal domain of unknown function 618 1318 1.1E-207 T 14-10-2018 IPR012728 Non-ribosomal peptide synthetase, C-terminal LH59_07985 be943456d11e117800d3f7750d4c161f 1324 SUPERFAMILY SSF51161 970 1080 1.07E-17 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily LH59_07985 be943456d11e117800d3f7750d4c161f 1324 SUPERFAMILY SSF56801 15 500 7.98E-142 T 14-10-2018 LH59_07985 be943456d11e117800d3f7750d4c161f 1324 Pfam PF00501 AMP-binding enzyme 24 406 1.0E-87 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 LH59_07985 be943456d11e117800d3f7750d4c161f 1324 SUPERFAMILY SSF51161 718 836 2.5E-13 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily LH59_07985 be943456d11e117800d3f7750d4c161f 1324 ProSitePatterns PS00012 Phosphopantetheine attachment site. 542 557 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site LH59_07985 be943456d11e117800d3f7750d4c161f 1324 ProSitePatterns PS00455 Putative AMP-binding domain signature. 157 168 - T 14-10-2018 IPR020845 AMP-binding, conserved site LH59_07985 be943456d11e117800d3f7750d4c161f 1324 SUPERFAMILY SSF51161 1206 1321 7.07E-17 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily LH59_07985 be943456d11e117800d3f7750d4c161f 1324 Gene3D G3DSA:3.30.300.30 401 514 1.4E-29 T 14-10-2018 LH59_07985 be943456d11e117800d3f7750d4c161f 1324 SUPERFAMILY SSF47336 512 584 6.54E-7 T 14-10-2018 IPR036736 ACP-like superfamily LH59_07985 be943456d11e117800d3f7750d4c161f 1324 Pfam PF00550 Phosphopantetheine attachment site 532 584 3.1E-6 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain LH59_07985 be943456d11e117800d3f7750d4c161f 1324 Gene3D G3DSA:2.160.10.10 955 1086 1.0E-9 T 14-10-2018 LH59_07985 be943456d11e117800d3f7750d4c161f 1324 Gene3D G3DSA:2.160.10.10 1219 1324 1.6E-12 T 14-10-2018 LH59_07985 be943456d11e117800d3f7750d4c161f 1324 Gene3D G3DSA:2.160.10.10 708 836 3.5E-8 T 14-10-2018 LH59_07985 be943456d11e117800d3f7750d4c161f 1324 Gene3D G3DSA:1.10.1200.10 516 592 3.2E-9 T 14-10-2018 IPR036736 ACP-like superfamily LH59_07985 be943456d11e117800d3f7750d4c161f 1324 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 1268 1296 0.017 T 14-10-2018 IPR001451 Hexapeptide repeat LH59_00120 1adb40d50ce188d43204a4ae00c3c7c9 264 Gene3D G3DSA:1.10.3720.10 6 262 2.6E-55 T 14-10-2018 IPR035906 MetI-like superfamily LH59_00120 1adb40d50ce188d43204a4ae00c3c7c9 264 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 249 1.2E-14 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_00120 1adb40d50ce188d43204a4ae00c3c7c9 264 SUPERFAMILY SSF161098 7 253 5.89E-56 T 14-10-2018 IPR035906 MetI-like superfamily LH59_00905 bff235f970e48599ab11654ba9e2a97d 129 Gene3D G3DSA:1.10.260.40 2 64 3.9E-10 T 14-10-2018 LH59_00905 bff235f970e48599ab11654ba9e2a97d 129 SUPERFAMILY SSF47413 2 66 1.78E-9 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 LH59_00905 bff235f970e48599ab11654ba9e2a97d 129 SMART SM00530 6 64 4.3E-8 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LH59_00905 bff235f970e48599ab11654ba9e2a97d 129 Pfam PF13560 Helix-turn-helix domain 3 61 2.9E-7 T 14-10-2018 LH59_03125 de871a003fc94f006e86a36ac75362a6 362 Pfam PF00005 ABC transporter 19 167 4.6E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_03125 de871a003fc94f006e86a36ac75362a6 362 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_03125 de871a003fc94f006e86a36ac75362a6 362 SUPERFAMILY SSF50331 243 336 2.44E-7 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal LH59_03125 de871a003fc94f006e86a36ac75362a6 362 Gene3D G3DSA:3.40.50.300 1 244 5.2E-73 T 14-10-2018 LH59_03125 de871a003fc94f006e86a36ac75362a6 362 SUPERFAMILY SSF52540 4 247 6.59E-79 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_03125 de871a003fc94f006e86a36ac75362a6 362 SMART SM00382 28 217 1.5E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_13245 24b159d4e4499abdcd19a0f84eae72c3 725 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 81 725 2.7E-82 T 14-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 LH59_13245 24b159d4e4499abdcd19a0f84eae72c3 725 Gene3D G3DSA:2.170.130.10 61 194 1.3E-32 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily LH59_13245 24b159d4e4499abdcd19a0f84eae72c3 725 Pfam PF07715 TonB-dependent Receptor Plug Domain 80 182 7.5E-23 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_13245 24b159d4e4499abdcd19a0f84eae72c3 725 SUPERFAMILY SSF56935 44 725 2.02E-130 T 14-10-2018 LH59_13245 24b159d4e4499abdcd19a0f84eae72c3 725 Gene3D G3DSA:2.40.170.20 196 725 2.4E-96 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_13245 24b159d4e4499abdcd19a0f84eae72c3 725 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 708 725 - T 14-10-2018 IPR010917 TonB-dependent receptor, conserved site LH59_13245 24b159d4e4499abdcd19a0f84eae72c3 725 Pfam PF00593 TonB dependent receptor 268 724 3.5E-52 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_23985 7bec53596a6bd8e198b65790ce5886af 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 3.2E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_23985 7bec53596a6bd8e198b65790ce5886af 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 3.2E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_23985 7bec53596a6bd8e198b65790ce5886af 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 3.2E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_23985 7bec53596a6bd8e198b65790ce5886af 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 63 5.8E-20 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_23985 7bec53596a6bd8e198b65790ce5886af 299 Gene3D G3DSA:1.10.10.10 1 87 7.8E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_23985 7bec53596a6bd8e198b65790ce5886af 299 Gene3D G3DSA:3.40.190.290 92 296 1.2E-48 T 14-10-2018 LH59_23985 7bec53596a6bd8e198b65790ce5886af 299 Pfam PF03466 LysR substrate binding domain 90 293 5.1E-43 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_23985 7bec53596a6bd8e198b65790ce5886af 299 SUPERFAMILY SSF46785 8 113 6.27E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_23985 7bec53596a6bd8e198b65790ce5886af 299 SUPERFAMILY SSF53850 91 296 8.54E-44 T 14-10-2018 LH59_08045 7c09324ed3c28247798ef1e87924b9ec 279 Pfam PF09339 IclR helix-turn-helix domain 5 51 4.8E-7 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_08045 7c09324ed3c28247798ef1e87924b9ec 279 Gene3D G3DSA:1.10.10.10 1 71 4.8E-12 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_08045 7c09324ed3c28247798ef1e87924b9ec 279 SUPERFAMILY SSF55781 58 244 9.16E-30 T 14-10-2018 LH59_08045 7c09324ed3c28247798ef1e87924b9ec 279 SMART SM00346 1 90 2.4E-6 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_08045 7c09324ed3c28247798ef1e87924b9ec 279 Gene3D G3DSA:3.30.450.40 72 239 6.7E-35 T 14-10-2018 IPR029016 GAF-like domain superfamily LH59_08045 7c09324ed3c28247798ef1e87924b9ec 279 Pfam PF01614 Bacterial transcriptional regulator 122 242 2.3E-11 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal LH59_08045 7c09324ed3c28247798ef1e87924b9ec 279 SUPERFAMILY SSF46785 2 72 2.88E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_23640 9e17a8b4020d54487112d28cbed78b08 297 Pfam PF03466 LysR substrate binding domain 94 293 6.8E-16 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_23640 9e17a8b4020d54487112d28cbed78b08 297 SUPERFAMILY SSF46785 1 89 3.08E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_23640 9e17a8b4020d54487112d28cbed78b08 297 SUPERFAMILY SSF53850 93 292 1.99E-18 T 14-10-2018 LH59_23640 9e17a8b4020d54487112d28cbed78b08 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 1.3E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_23640 9e17a8b4020d54487112d28cbed78b08 297 Gene3D G3DSA:1.10.10.10 3 88 1.2E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_23640 9e17a8b4020d54487112d28cbed78b08 297 Gene3D G3DSA:3.40.190.10 106 166 1.2E-12 T 14-10-2018 LH59_23640 9e17a8b4020d54487112d28cbed78b08 297 Gene3D G3DSA:3.40.190.10 167 246 1.2E-12 T 14-10-2018 LH59_09600 1412c7e4b7ea794011937fcdeb50fae7 244 SUPERFAMILY SSF46894 175 239 3.74E-17 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LH59_09600 1412c7e4b7ea794011937fcdeb50fae7 244 SMART SM00421 181 238 9.1E-16 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_09600 1412c7e4b7ea794011937fcdeb50fae7 244 Gene3D G3DSA:1.10.10.10 173 241 2.0E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_09600 1412c7e4b7ea794011937fcdeb50fae7 244 SMART SM00448 39 154 1.9E-13 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_09600 1412c7e4b7ea794011937fcdeb50fae7 244 Gene3D G3DSA:3.40.50.2300 38 169 9.5E-23 T 14-10-2018 LH59_09600 1412c7e4b7ea794011937fcdeb50fae7 244 ProSitePatterns PS00622 LuxR-type HTH domain signature. 198 225 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_09600 1412c7e4b7ea794011937fcdeb50fae7 244 Pfam PF00072 Response regulator receiver domain 41 154 2.4E-17 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_09600 1412c7e4b7ea794011937fcdeb50fae7 244 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 214 226 2.1E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_09600 1412c7e4b7ea794011937fcdeb50fae7 244 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 198 214 2.1E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_09600 1412c7e4b7ea794011937fcdeb50fae7 244 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 198 2.1E-9 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_09600 1412c7e4b7ea794011937fcdeb50fae7 244 SUPERFAMILY SSF52172 39 166 1.31E-21 T 14-10-2018 IPR011006 CheY-like superfamily LH59_09600 1412c7e4b7ea794011937fcdeb50fae7 244 Pfam PF00196 Bacterial regulatory proteins, luxR family 183 236 1.6E-15 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_15770 6384fbc189b8040882ff0d3d160551df 347 SUPERFAMILY SSF52172 15 150 5.69E-29 T 14-10-2018 IPR011006 CheY-like superfamily LH59_15770 6384fbc189b8040882ff0d3d160551df 347 Pfam PF00072 Response regulator receiver domain 20 132 2.5E-18 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_15770 6384fbc189b8040882ff0d3d160551df 347 Pfam PF00990 Diguanylate cyclase, GGDEF domain 171 331 2.8E-47 T 14-10-2018 IPR000160 GGDEF domain LH59_15770 6384fbc189b8040882ff0d3d160551df 347 Gene3D G3DSA:3.40.50.2300 9 154 7.6E-30 T 14-10-2018 LH59_15770 6384fbc189b8040882ff0d3d160551df 347 SUPERFAMILY SSF55073 175 333 3.45E-49 T 14-10-2018 IPR029787 Nucleotide cyclase LH59_15770 6384fbc189b8040882ff0d3d160551df 347 SMART SM00448 18 132 1.2E-20 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_15770 6384fbc189b8040882ff0d3d160551df 347 SMART SM00267 159 335 8.0E-58 T 14-10-2018 IPR000160 GGDEF domain LH59_15770 6384fbc189b8040882ff0d3d160551df 347 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 167 333 6.4E-51 T 14-10-2018 IPR000160 GGDEF domain LH59_15770 6384fbc189b8040882ff0d3d160551df 347 Gene3D G3DSA:3.30.70.270 155 335 4.3E-60 T 14-10-2018 LH59_10915 607642bed28c295c21c352646503a756 267 Pfam PF00392 Bacterial regulatory proteins, gntR family 42 104 2.4E-19 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_10915 607642bed28c295c21c352646503a756 267 Gene3D G3DSA:1.10.10.10 35 107 3.8E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_10915 607642bed28c295c21c352646503a756 267 SMART SM00345 45 104 4.5E-21 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_10915 607642bed28c295c21c352646503a756 267 Pfam PF07729 FCD domain 130 254 3.2E-26 T 14-10-2018 IPR011711 GntR, C-terminal LH59_10915 607642bed28c295c21c352646503a756 267 SMART SM00895 128 255 2.1E-23 T 14-10-2018 IPR011711 GntR, C-terminal LH59_10915 607642bed28c295c21c352646503a756 267 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 64 78 1.6E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_10915 607642bed28c295c21c352646503a756 267 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 78 94 1.6E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_10915 607642bed28c295c21c352646503a756 267 Gene3D G3DSA:1.20.120.530 125 266 2.7E-30 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_10915 607642bed28c295c21c352646503a756 267 SUPERFAMILY SSF48008 125 262 2.48E-27 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_10915 607642bed28c295c21c352646503a756 267 SUPERFAMILY SSF46785 37 108 8.75E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_13285 e1804cbaa7d7eaf754918008f4529e8c 527 Gene3D G3DSA:3.30.465.10 438 517 1.3E-21 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 LH59_13285 e1804cbaa7d7eaf754918008f4529e8c 527 SMART SM01091 438 518 1.1E-21 T 14-10-2018 IPR005170 Transporter-associated domain LH59_13285 e1804cbaa7d7eaf754918008f4529e8c 527 SUPERFAMILY SSF54631 294 426 1.64E-21 T 14-10-2018 LH59_13285 e1804cbaa7d7eaf754918008f4529e8c 527 Pfam PF03741 Integral membrane protein TerC family 17 206 1.3E-49 T 14-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 LH59_13285 e1804cbaa7d7eaf754918008f4529e8c 527 Pfam PF03471 Transporter associated domain 439 516 2.0E-17 T 14-10-2018 IPR005170 Transporter-associated domain LH59_13285 e1804cbaa7d7eaf754918008f4529e8c 527 Gene3D G3DSA:3.10.580.10 287 437 1.8E-38 T 14-10-2018 LH59_13285 e1804cbaa7d7eaf754918008f4529e8c 527 SUPERFAMILY SSF56176 436 520 1.45E-17 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 LH59_13285 e1804cbaa7d7eaf754918008f4529e8c 527 Pfam PF00571 CBS domain 374 424 3.6E-6 T 14-10-2018 IPR000644 CBS domain LH59_12440 7f7a18fda0ae17c81a218a226a5f0a9b 656 SUPERFAMILY SSF54534 258 368 3.01E-28 T 14-10-2018 LH59_12440 7f7a18fda0ae17c81a218a226a5f0a9b 656 Pfam PF00639 PPIC-type PPIASE domain 272 367 1.5E-26 T 14-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 LH59_12440 7f7a18fda0ae17c81a218a226a5f0a9b 656 SUPERFAMILY SSF109998 42 236 8.44E-33 T 14-10-2018 IPR027304 Trigger factor/SurA domain superfamily LH59_12440 7f7a18fda0ae17c81a218a226a5f0a9b 656 Gene3D G3DSA:3.10.50.40 266 370 2.9E-36 T 14-10-2018 LH59_12440 7f7a18fda0ae17c81a218a226a5f0a9b 656 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 307 328 - T 14-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 LH59_12440 7f7a18fda0ae17c81a218a226a5f0a9b 656 Gene3D G3DSA:1.10.4030.30 42 192 6.5E-15 T 14-10-2018 LH59_12440 7f7a18fda0ae17c81a218a226a5f0a9b 656 Gene3D G3DSA:1.10.4030.30 242 382 2.9E-36 T 14-10-2018 LH59_12440 7f7a18fda0ae17c81a218a226a5f0a9b 656 Pfam PF13624 SurA N-terminal domain 1 162 4.1E-49 T 14-10-2018 LH59_14470 aaa7899f057c2e6b85af81c42f3f2083 379 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 199 219 - T 14-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site LH59_14470 aaa7899f057c2e6b85af81c42f3f2083 379 SUPERFAMILY SSF53383 3 373 1.36E-74 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_14470 aaa7899f057c2e6b85af81c42f3f2083 379 Gene3D G3DSA:3.40.640.10 29 287 2.4E-90 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_14470 aaa7899f057c2e6b85af81c42f3f2083 379 Pfam PF00266 Aminotransferase class-V 59 369 5.8E-47 T 14-10-2018 IPR000192 Aminotransferase class V domain LH59_14470 aaa7899f057c2e6b85af81c42f3f2083 379 Gene3D G3DSA:3.90.1150.10 14 370 2.4E-90 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_16750 a35a5be8375f83841ee2f5c35f1742d3 536 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 255 269 - T 14-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 LH59_16750 a35a5be8375f83841ee2f5c35f1742d3 536 PIRSF PIRSF000137 1 536 3.4E-147 T 14-10-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 LH59_16750 a35a5be8375f83841ee2f5c35f1742d3 536 Gene3D G3DSA:3.30.410.40 152 471 1.2E-178 T 14-10-2018 LH59_16750 a35a5be8375f83841ee2f5c35f1742d3 536 Pfam PF00732 GMC oxidoreductase 6 296 1.3E-87 T 14-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 LH59_16750 a35a5be8375f83841ee2f5c35f1742d3 536 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 83 106 - T 14-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 LH59_16750 a35a5be8375f83841ee2f5c35f1742d3 536 SUPERFAMILY SSF54373 291 474 8.34E-60 T 14-10-2018 LH59_16750 a35a5be8375f83841ee2f5c35f1742d3 536 Gene3D G3DSA:4.10.450.10 39 197 1.2E-178 T 14-10-2018 IPR027424 Glucose Oxidase, domain 2 KEGG: 00260+1.2.1.8+1.1.99.1|MetaCyc: PWY-3722|MetaCyc: PWY-7494|Reactome: R-HSA-6798163 LH59_16750 a35a5be8375f83841ee2f5c35f1742d3 536 SUPERFAMILY SSF51905 3 532 7.12E-89 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_16750 a35a5be8375f83841ee2f5c35f1742d3 536 Pfam PF05199 GMC oxidoreductase 388 523 7.9E-39 T 14-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 LH59_16750 a35a5be8375f83841ee2f5c35f1742d3 536 Gene3D G3DSA:3.50.50.60 5 528 1.2E-178 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_16750 a35a5be8375f83841ee2f5c35f1742d3 536 Gene3D G3DSA:1.10.1220.110 98 151 1.2E-178 T 14-10-2018 LH59_16685 65c9d0ea7ba7c2859e0a1668c91eca2d 441 Pfam PF00083 Sugar (and other) transporter 18 228 2.8E-22 T 14-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 LH59_16685 65c9d0ea7ba7c2859e0a1668c91eca2d 441 SUPERFAMILY SSF103473 15 429 2.88E-61 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_16685 65c9d0ea7ba7c2859e0a1668c91eca2d 441 Gene3D G3DSA:1.20.1250.20 13 432 6.7E-56 T 14-10-2018 LH59_17615 05025d01db3e6ee6dfd40359ccea2cd8 298 Gene3D G3DSA:3.40.50.150 102 287 2.6E-48 T 14-10-2018 LH59_17615 05025d01db3e6ee6dfd40359ccea2cd8 298 SUPERFAMILY SSF53335 12 265 3.22E-53 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_17615 05025d01db3e6ee6dfd40359ccea2cd8 298 TIGRFAM TIGR03533 L3_gln_methyl: protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific 9 293 4.8E-124 T 14-10-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 LH59_17615 05025d01db3e6ee6dfd40359ccea2cd8 298 Gene3D G3DSA:1.10.8.10 11 101 7.7E-7 T 14-10-2018 LH59_17615 05025d01db3e6ee6dfd40359ccea2cd8 298 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 11 296 1.3E-72 T 14-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 LH59_17615 05025d01db3e6ee6dfd40359ccea2cd8 298 Pfam PF05175 Methyltransferase small domain 130 213 2.2E-16 T 14-10-2018 IPR007848 Methyltransferase small domain GO:0008168 LH59_17615 05025d01db3e6ee6dfd40359ccea2cd8 298 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 202 208 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 LH59_17615 05025d01db3e6ee6dfd40359ccea2cd8 298 Hamap MF_02125 50S ribosomal protein L3 glutamine methyltransferase [prmB]. 2 298 52.787 T 14-10-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 LH59_17615 05025d01db3e6ee6dfd40359ccea2cd8 298 PIRSF PIRSF037167 1 298 1.7E-130 T 14-10-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 LH59_12945 8c70d05310d4580a25fdced774430646 411 Pfam PF02653 Branched-chain amino acid transport system / permease component 107 392 3.7E-52 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_12945 8c70d05310d4580a25fdced774430646 411 Pfam PF11862 Domain of unknown function (DUF3382) 4 97 3.5E-24 T 14-10-2018 IPR021807 High-affinity branched-chain amino acid transport system permease, LivHM, N-terminal LH59_27870 18438ba5f5decb6339ef1ebf48bbd0da 63 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 60 7.1E-21 T 14-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27870 18438ba5f5decb6339ef1ebf48bbd0da 63 Gene3D G3DSA:1.10.287.310 1 62 6.3E-26 T 14-10-2018 LH59_27870 18438ba5f5decb6339ef1ebf48bbd0da 63 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 17.408 T 14-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27870 18438ba5f5decb6339ef1ebf48bbd0da 63 SUPERFAMILY SSF46561 1 61 5.36E-20 T 14-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27870 18438ba5f5decb6339ef1ebf48bbd0da 63 Pfam PF00831 Ribosomal L29 protein 4 60 4.5E-21 T 14-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27870 18438ba5f5decb6339ef1ebf48bbd0da 63 ProSitePatterns PS00579 Ribosomal protein L29 signature. 39 53 - T 14-10-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_21940 d5049231468ccc5508110f02b05f629e 158 PIRSF PIRSF006092 1 158 5.9E-53 T 14-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 LH59_21940 d5049231468ccc5508110f02b05f629e 158 Gene3D G3DSA:3.10.50.30 76 158 4.8E-29 T 14-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 LH59_21940 d5049231468ccc5508110f02b05f629e 158 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 83 157 2.6E-29 T 14-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 LH59_21940 d5049231468ccc5508110f02b05f629e 158 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 121 137 - T 14-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 LH59_21940 d5049231468ccc5508110f02b05f629e 158 Hamap MF_00105 Transcription elongation factor GreA [greA]. 2 156 33.009 T 14-10-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 LH59_21940 d5049231468ccc5508110f02b05f629e 158 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 5 155 2.0E-57 T 14-10-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 LH59_21940 d5049231468ccc5508110f02b05f629e 158 SUPERFAMILY SSF46557 4 78 8.76E-28 T 14-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 LH59_21940 d5049231468ccc5508110f02b05f629e 158 Gene3D G3DSA:1.10.287.180 1 75 3.4E-31 T 14-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 LH59_21940 d5049231468ccc5508110f02b05f629e 158 Pfam PF03449 Transcription elongation factor, N-terminal 4 73 3.9E-32 T 14-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 LH59_21940 d5049231468ccc5508110f02b05f629e 158 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 17 48 - T 14-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 LH59_21940 d5049231468ccc5508110f02b05f629e 158 SUPERFAMILY SSF54534 83 157 1.31E-23 T 14-10-2018 LH59_05700 78632ac3321db652df9085a33ea24190 328 Pfam PF12833 Helix-turn-helix domain 238 316 5.6E-19 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_05700 78632ac3321db652df9085a33ea24190 328 SUPERFAMILY SSF46689 215 265 1.08E-8 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_05700 78632ac3321db652df9085a33ea24190 328 Gene3D G3DSA:1.10.10.60 212 320 1.5E-25 T 14-10-2018 LH59_05700 78632ac3321db652df9085a33ea24190 328 SUPERFAMILY SSF46689 268 318 2.33E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_05700 78632ac3321db652df9085a33ea24190 328 SMART SM00342 232 315 1.4E-27 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_05700 78632ac3321db652df9085a33ea24190 328 Pfam PF12852 Cupin 12 200 2.2E-27 T 14-10-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain LH59_05700 78632ac3321db652df9085a33ea24190 328 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 269 311 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 LH59_04810 eed81943e3f4490ed4c0d703450094e5 311 Gene3D G3DSA:3.90.550.10 3 220 1.4E-35 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases LH59_04810 eed81943e3f4490ed4c0d703450094e5 311 Pfam PF00535 Glycosyl transferase family 2 9 115 3.8E-27 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 LH59_04810 eed81943e3f4490ed4c0d703450094e5 311 SUPERFAMILY SSF53448 6 259 1.03E-40 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases LH59_10775 d6002df5c6f06af21f7be2f2ead5b479 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 5.3E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10775 d6002df5c6f06af21f7be2f2ead5b479 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 5.3E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10775 d6002df5c6f06af21f7be2f2ead5b479 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 5.3E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10775 d6002df5c6f06af21f7be2f2ead5b479 254 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 176 5.4E-5 T 14-10-2018 LH59_10775 d6002df5c6f06af21f7be2f2ead5b479 254 Gene3D G3DSA:3.40.50.720 2 249 1.8E-74 T 14-10-2018 LH59_10775 d6002df5c6f06af21f7be2f2ead5b479 254 SUPERFAMILY SSF51735 8 247 1.29E-75 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_10775 d6002df5c6f06af21f7be2f2ead5b479 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 245 8.0E-64 T 14-10-2018 LH59_10775 d6002df5c6f06af21f7be2f2ead5b479 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LH59_10775 d6002df5c6f06af21f7be2f2ead5b479 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.2E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10775 d6002df5c6f06af21f7be2f2ead5b479 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 1.2E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10775 d6002df5c6f06af21f7be2f2ead5b479 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.2E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10775 d6002df5c6f06af21f7be2f2ead5b479 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 1.2E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10775 d6002df5c6f06af21f7be2f2ead5b479 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 1.2E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10775 d6002df5c6f06af21f7be2f2ead5b479 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 1.2E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_17040 d174b402f8d844963f1ff26368d24e67 464 SMART SM00388 245 308 1.2E-12 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_17040 d174b402f8d844963f1ff26368d24e67 464 Pfam PF00512 His Kinase A (phospho-acceptor) domain 246 307 6.9E-14 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_17040 d174b402f8d844963f1ff26368d24e67 464 SMART SM00387 351 463 9.5E-29 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_17040 d174b402f8d844963f1ff26368d24e67 464 SUPERFAMILY SSF55874 302 461 8.79E-38 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_17040 d174b402f8d844963f1ff26368d24e67 464 Gene3D G3DSA:3.30.565.10 312 463 1.7E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_17040 d174b402f8d844963f1ff26368d24e67 464 Pfam PF00672 HAMP domain 189 241 7.0E-11 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_17040 d174b402f8d844963f1ff26368d24e67 464 SMART SM00304 189 244 3.4E-11 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_17040 d174b402f8d844963f1ff26368d24e67 464 SUPERFAMILY SSF47384 228 306 3.53E-14 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 LH59_17040 d174b402f8d844963f1ff26368d24e67 464 Gene3D G3DSA:1.10.287.130 193 307 1.8E-26 T 14-10-2018 LH59_17040 d174b402f8d844963f1ff26368d24e67 464 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 352 460 1.9E-16 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_17040 d174b402f8d844963f1ff26368d24e67 464 SUPERFAMILY SSF158472 189 243 1.57E-8 T 14-10-2018 LH59_17040 d174b402f8d844963f1ff26368d24e67 464 PRINTS PR00344 Bacterial sensor protein C-terminal signature 423 441 1.2E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_17040 d174b402f8d844963f1ff26368d24e67 464 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 416 1.2E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_17040 d174b402f8d844963f1ff26368d24e67 464 PRINTS PR00344 Bacterial sensor protein C-terminal signature 388 402 1.2E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_17040 d174b402f8d844963f1ff26368d24e67 464 PRINTS PR00344 Bacterial sensor protein C-terminal signature 447 460 1.2E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_26210 eb2f7d6f5c03e0c65d42d80f306d0ed8 301 SUPERFAMILY SSF51735 7 168 5.77E-39 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_26210 eb2f7d6f5c03e0c65d42d80f306d0ed8 301 Gene3D G3DSA:3.40.50.720 2 170 1.1E-47 T 14-10-2018 LH59_26210 eb2f7d6f5c03e0c65d42d80f306d0ed8 301 SUPERFAMILY SSF48179 171 293 4.99E-38 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 LH59_26210 eb2f7d6f5c03e0c65d42d80f306d0ed8 301 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 172 291 3.2E-37 T 14-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 LH59_26210 eb2f7d6f5c03e0c65d42d80f306d0ed8 301 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 10 166 1.2E-38 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 LH59_26210 eb2f7d6f5c03e0c65d42d80f306d0ed8 301 Gene3D G3DSA:1.10.1040.10 171 296 3.3E-43 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 LH59_26210 eb2f7d6f5c03e0c65d42d80f306d0ed8 301 PIRSF PIRSF000103 2 295 6.8E-69 T 14-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 LH59_08895 886f17f68c9001f25126b89aaefa0e84 539 Pfam PF07690 Major Facilitator Superfamily 40 432 1.1E-52 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_08895 886f17f68c9001f25126b89aaefa0e84 539 SUPERFAMILY SSF103473 25 524 1.31E-63 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_08895 886f17f68c9001f25126b89aaefa0e84 539 Gene3D G3DSA:1.20.1720.10 37 240 2.0E-46 T 14-10-2018 LH59_08895 886f17f68c9001f25126b89aaefa0e84 539 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 36 518 9.4E-159 T 14-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 LH59_21375 cfeeddba7bea6cdfe1f38c7b4ed9aac5 157 SUPERFAMILY SSF54637 14 156 4.75E-32 T 14-10-2018 IPR029069 HotDog domain superfamily LH59_21375 cfeeddba7bea6cdfe1f38c7b4ed9aac5 157 Pfam PF13452 N-terminal half of MaoC dehydratase 21 144 7.1E-8 T 14-10-2018 IPR039569 N-terminal of MaoC-like dehydratase Reactome: R-HSA-193368|Reactome: R-HSA-2046106|Reactome: R-HSA-389887|Reactome: R-HSA-390247|Reactome: R-HSA-9033241|Reactome: R-HSA-9033500 LH59_21375 cfeeddba7bea6cdfe1f38c7b4ed9aac5 157 Gene3D G3DSA:3.10.129.10 7 156 9.4E-36 T 14-10-2018 LH59_04730 55ba75ef13fd7b3ca289033914c18c38 652 SUPERFAMILY SSF52540 5 227 5.21E-68 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_04730 55ba75ef13fd7b3ca289033914c18c38 652 Pfam PF00005 ABC transporter 25 173 4.4E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_04730 55ba75ef13fd7b3ca289033914c18c38 652 Gene3D G3DSA:3.40.50.300 3 273 9.1E-70 T 14-10-2018 LH59_04730 55ba75ef13fd7b3ca289033914c18c38 652 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_04730 55ba75ef13fd7b3ca289033914c18c38 652 Pfam PF12704 MacB-like periplasmic core domain 275 494 1.8E-40 T 14-10-2018 IPR025857 MacB-like periplasmic core domain LH59_04730 55ba75ef13fd7b3ca289033914c18c38 652 Pfam PF02687 FtsX-like permease family 556 645 1.7E-11 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 LH59_04730 55ba75ef13fd7b3ca289033914c18c38 652 SMART SM00382 34 221 7.0E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_01080 91932e21b71c54c8b87f4437caf00e23 488 Gene3D G3DSA:3.50.50.60 257 413 1.3E-36 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_01080 91932e21b71c54c8b87f4437caf00e23 488 PRINTS PR00419 Adrenodoxin reductase family signature 145 167 2.3E-20 T 14-10-2018 LH59_01080 91932e21b71c54c8b87f4437caf00e23 488 PRINTS PR00419 Adrenodoxin reductase family signature 168 181 2.3E-20 T 14-10-2018 LH59_01080 91932e21b71c54c8b87f4437caf00e23 488 PRINTS PR00419 Adrenodoxin reductase family signature 294 308 2.3E-20 T 14-10-2018 LH59_01080 91932e21b71c54c8b87f4437caf00e23 488 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 24 130 3.7E-26 T 14-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 LH59_01080 91932e21b71c54c8b87f4437caf00e23 488 SUPERFAMILY SSF51971 142 414 8.36E-63 T 14-10-2018 LH59_01080 91932e21b71c54c8b87f4437caf00e23 488 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 144 469 1.6E-25 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LH59_01080 91932e21b71c54c8b87f4437caf00e23 488 Gene3D G3DSA:3.40.50.720 143 256 4.3E-14 T 14-10-2018 LH59_01080 91932e21b71c54c8b87f4437caf00e23 488 SUPERFAMILY SSF51971 371 481 4.36E-11 T 14-10-2018 LH59_01080 91932e21b71c54c8b87f4437caf00e23 488 SUPERFAMILY SSF46548 2 154 4.71E-41 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 LH59_01080 91932e21b71c54c8b87f4437caf00e23 488 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 487 8.5E-226 T 14-10-2018 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 LH59_01080 91932e21b71c54c8b87f4437caf00e23 488 Gene3D G3DSA:1.10.1060.10 7 142 4.6E-25 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 LH59_09230 6d383598a056f513052a39578b6d37ff 70 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 4.0E-15 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_09230 6d383598a056f513052a39578b6d37ff 70 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 4.0E-15 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_09230 6d383598a056f513052a39578b6d37ff 70 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 4.0E-15 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_09230 6d383598a056f513052a39578b6d37ff 70 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 4.0E-15 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_09230 6d383598a056f513052a39578b6d37ff 70 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 14-10-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_09230 6d383598a056f513052a39578b6d37ff 70 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 16 57 1.0E-16 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_09230 6d383598a056f513052a39578b6d37ff 70 Pfam PF01165 Ribosomal protein S21 4 57 7.6E-21 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_09230 6d383598a056f513052a39578b6d37ff 70 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 2 59 3.0E-23 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_09230 6d383598a056f513052a39578b6d37ff 70 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 19.94 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_09230 6d383598a056f513052a39578b6d37ff 70 Gene3D G3DSA:1.20.5.1150 16 54 8.9E-20 T 14-10-2018 IPR038380 Ribosomal protein S21 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_02565 ecd71f944a86076a5ddd9a4d6633de70 345 Gene3D G3DSA:3.90.180.10 9 331 2.3E-102 T 14-10-2018 LH59_02565 ecd71f944a86076a5ddd9a4d6633de70 345 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 LH59_02565 ecd71f944a86076a5ddd9a4d6633de70 345 SUPERFAMILY SSF51735 143 310 3.02E-34 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_02565 ecd71f944a86076a5ddd9a4d6633de70 345 SMART SM00829 8 343 2.5E-5 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 LH59_02565 ecd71f944a86076a5ddd9a4d6633de70 345 Pfam PF00107 Zinc-binding dehydrogenase 179 303 1.7E-22 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 LH59_02565 ecd71f944a86076a5ddd9a4d6633de70 345 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 139 6.3E-32 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 LH59_02565 ecd71f944a86076a5ddd9a4d6633de70 345 SUPERFAMILY SSF50129 4 177 4.72E-52 T 14-10-2018 IPR011032 GroES-like superfamily LH59_02565 ecd71f944a86076a5ddd9a4d6633de70 345 Gene3D G3DSA:3.40.50.720 156 292 2.3E-102 T 14-10-2018 LH59_03295 8b7dfb075bee585a86aa247395152684 813 Pfam PF13549 ATP-grasp domain 499 612 1.3E-22 T 14-10-2018 LH59_03295 8b7dfb075bee585a86aa247395152684 813 Gene3D G3DSA:3.40.630.30 643 810 4.1E-44 T 14-10-2018 LH59_03295 8b7dfb075bee585a86aa247395152684 813 Gene3D G3DSA:3.40.50.261 275 439 5.4E-32 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 LH59_03295 8b7dfb075bee585a86aa247395152684 813 Pfam PF00583 Acetyltransferase (GNAT) family 722 794 1.5E-11 T 14-10-2018 IPR000182 GNAT domain LH59_03295 8b7dfb075bee585a86aa247395152684 813 Gene3D G3DSA:3.40.50.261 125 274 2.3E-38 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 LH59_03295 8b7dfb075bee585a86aa247395152684 813 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 146 271 7.1E-35 T 14-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain LH59_03295 8b7dfb075bee585a86aa247395152684 813 SUPERFAMILY SSF52210 127 271 2.49E-31 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 LH59_03295 8b7dfb075bee585a86aa247395152684 813 SUPERFAMILY SSF52210 277 435 3.66E-27 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 LH59_03295 8b7dfb075bee585a86aa247395152684 813 SUPERFAMILY SSF55729 652 800 1.89E-20 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_03295 8b7dfb075bee585a86aa247395152684 813 Gene3D G3DSA:3.30.470.20 453 612 1.4E-22 T 14-10-2018 LH59_01035 9a7809766d0e9f60a7f710f551b8eb51 290 Pfam PF03466 LysR substrate binding domain 88 288 1.6E-43 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_01035 9a7809766d0e9f60a7f710f551b8eb51 290 SUPERFAMILY SSF46785 4 112 6.05E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_01035 9a7809766d0e9f60a7f710f551b8eb51 290 Gene3D G3DSA:1.10.10.10 3 92 2.9E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_01035 9a7809766d0e9f60a7f710f551b8eb51 290 SUPERFAMILY SSF53850 90 288 5.72E-42 T 14-10-2018 LH59_01035 9a7809766d0e9f60a7f710f551b8eb51 290 Gene3D G3DSA:3.40.190.290 93 289 3.8E-38 T 14-10-2018 LH59_01035 9a7809766d0e9f60a7f710f551b8eb51 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 1.1E-16 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_04500 e2e9c8c2f92eca9caabca27ad1c47ddc 506 SUPERFAMILY SSF56801 7 505 7.59E-136 T 14-10-2018 LH59_04500 e2e9c8c2f92eca9caabca27ad1c47ddc 506 Pfam PF13193 AMP-binding enzyme C-terminal domain 420 495 8.8E-13 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain LH59_04500 e2e9c8c2f92eca9caabca27ad1c47ddc 506 Gene3D G3DSA:3.30.300.30 405 505 1.0E-25 T 14-10-2018 LH59_04500 e2e9c8c2f92eca9caabca27ad1c47ddc 506 Pfam PF00501 AMP-binding enzyme 15 411 1.1E-94 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 LH59_04500 e2e9c8c2f92eca9caabca27ad1c47ddc 506 ProSitePatterns PS00455 Putative AMP-binding domain signature. 164 175 - T 14-10-2018 IPR020845 AMP-binding, conserved site LH59_04500 e2e9c8c2f92eca9caabca27ad1c47ddc 506 Gene3D G3DSA:3.40.50.12780 1 404 4.4E-103 T 14-10-2018 LH59_25570 a92a8cd826657e54677a515fbc9da36f 309 SUPERFAMILY SSF46785 3 82 1.17E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_25570 a92a8cd826657e54677a515fbc9da36f 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 8.0E-21 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_25570 a92a8cd826657e54677a515fbc9da36f 309 Pfam PF03466 LysR substrate binding domain 95 293 2.0E-16 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_25570 a92a8cd826657e54677a515fbc9da36f 309 SUPERFAMILY SSF53850 95 297 6.88E-17 T 14-10-2018 LH59_25570 a92a8cd826657e54677a515fbc9da36f 309 Gene3D G3DSA:3.40.190.290 97 297 1.9E-15 T 14-10-2018 LH59_25570 a92a8cd826657e54677a515fbc9da36f 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 2.7E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_25570 a92a8cd826657e54677a515fbc9da36f 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 2.7E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_25570 a92a8cd826657e54677a515fbc9da36f 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 2.7E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_25570 a92a8cd826657e54677a515fbc9da36f 309 Gene3D G3DSA:1.10.10.10 5 96 1.7E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_27720 ba39f5ae2407dc2a479e543bf5fec41e 130 SUPERFAMILY SSF64263 1 119 3.92E-50 T 14-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_27720 ba39f5ae2407dc2a479e543bf5fec41e 130 TIGRFAM TIGR00059 L17: ribosomal protein bL17 7 117 1.7E-46 T 14-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_27720 ba39f5ae2407dc2a479e543bf5fec41e 130 Pfam PF01196 Ribosomal protein L17 20 116 5.6E-35 T 14-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_27720 ba39f5ae2407dc2a479e543bf5fec41e 130 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 14-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_27720 ba39f5ae2407dc2a479e543bf5fec41e 130 Gene3D G3DSA:3.90.1030.10 1 116 1.9E-47 T 14-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_27720 ba39f5ae2407dc2a479e543bf5fec41e 130 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 26.876 T 14-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_08000 a9359a7c60b44baa701c0a92ad752374 293 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 241 254 - T 14-10-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site LH59_08000 a9359a7c60b44baa701c0a92ad752374 293 SUPERFAMILY SSF52210 128 291 1.3E-51 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 LH59_08000 a9359a7c60b44baa701c0a92ad752374 293 Gene3D G3DSA:3.40.50.261 129 293 3.4E-67 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 LH59_08000 a9359a7c60b44baa701c0a92ad752374 293 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 293 8.9E-127 T 14-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 LH59_08000 a9359a7c60b44baa701c0a92ad752374 293 Gene3D G3DSA:3.40.50.720 2 128 8.2E-43 T 14-10-2018 LH59_08000 a9359a7c60b44baa701c0a92ad752374 293 PRINTS PR01798 Succinyl-CoA synthase signature 85 102 5.8E-34 T 14-10-2018 LH59_08000 a9359a7c60b44baa701c0a92ad752374 293 PRINTS PR01798 Succinyl-CoA synthase signature 182 200 5.8E-34 T 14-10-2018 LH59_08000 a9359a7c60b44baa701c0a92ad752374 293 PRINTS PR01798 Succinyl-CoA synthase signature 213 226 5.8E-34 T 14-10-2018 LH59_08000 a9359a7c60b44baa701c0a92ad752374 293 PRINTS PR01798 Succinyl-CoA synthase signature 245 262 5.8E-34 T 14-10-2018 LH59_08000 a9359a7c60b44baa701c0a92ad752374 293 SUPERFAMILY SSF51735 1 127 8.45E-36 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_08000 a9359a7c60b44baa701c0a92ad752374 293 SMART SM00881 4 103 3.0E-29 T 14-10-2018 IPR003781 CoA-binding GO:0048037 LH59_08000 a9359a7c60b44baa701c0a92ad752374 293 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 293 40.535 T 14-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 LH59_08000 a9359a7c60b44baa701c0a92ad752374 293 Pfam PF00549 CoA-ligase 156 271 2.2E-15 T 14-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 LH59_08000 a9359a7c60b44baa701c0a92ad752374 293 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 157 186 - T 14-10-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site LH59_08000 a9359a7c60b44baa701c0a92ad752374 293 PIRSF PIRSF001553 1 293 1.0E-116 T 14-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 LH59_08000 a9359a7c60b44baa701c0a92ad752374 293 Pfam PF02629 CoA binding domain 6 102 2.4E-23 T 14-10-2018 IPR003781 CoA-binding GO:0048037 LH59_04075 b199154b7239d8f6a725c9c8012088eb 307 SUPERFAMILY SSF54211 143 281 9.1E-51 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold LH59_04075 b199154b7239d8f6a725c9c8012088eb 307 Hamap MF_00388 UDP-3-O-acyl-N-acetylglucosamine deacetylase [lpxC]. 2 283 45.216 T 14-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 LH59_04075 b199154b7239d8f6a725c9c8012088eb 307 Pfam PF03331 UDP-3-O-acyl N-acetylglycosamine deacetylase 4 279 1.7E-104 T 14-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 LH59_04075 b199154b7239d8f6a725c9c8012088eb 307 Gene3D G3DSA:3.30.230.20 1 127 2.1E-46 T 14-10-2018 IPR015870 UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 LH59_04075 b199154b7239d8f6a725c9c8012088eb 307 SUPERFAMILY SSF54211 3 125 4.32E-41 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold LH59_04075 b199154b7239d8f6a725c9c8012088eb 307 Gene3D G3DSA:3.30.1700.10 128 306 8.8E-66 T 14-10-2018 IPR011334 UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 LH59_04075 b199154b7239d8f6a725c9c8012088eb 307 TIGRFAM TIGR00325 lpxC: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 3 301 3.4E-118 T 14-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 LH59_18230 d146e91a1619200c5f0f7f9c8af04c25 307 Gene3D G3DSA:1.10.10.10 9 95 7.9E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_18230 d146e91a1619200c5f0f7f9c8af04c25 307 Pfam PF03466 LysR substrate binding domain 94 299 1.1E-41 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_18230 d146e91a1619200c5f0f7f9c8af04c25 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 6.4E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_18230 d146e91a1619200c5f0f7f9c8af04c25 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 6.4E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_18230 d146e91a1619200c5f0f7f9c8af04c25 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 6.4E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_18230 d146e91a1619200c5f0f7f9c8af04c25 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 13 69 1.7E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_18230 d146e91a1619200c5f0f7f9c8af04c25 307 SUPERFAMILY SSF46785 11 92 1.26E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_18230 d146e91a1619200c5f0f7f9c8af04c25 307 Gene3D G3DSA:3.40.190.10 97 298 4.2E-61 T 14-10-2018 LH59_18230 d146e91a1619200c5f0f7f9c8af04c25 307 Gene3D G3DSA:3.40.190.10 170 271 4.2E-61 T 14-10-2018 LH59_18230 d146e91a1619200c5f0f7f9c8af04c25 307 SUPERFAMILY SSF53850 96 303 2.17E-43 T 14-10-2018 LH59_20210 9f34297e7df8fcf3fbe8bb9672c0a14a 580 Pfam PF04185 Phosphoesterase family 85 549 2.9E-99 T 14-10-2018 IPR007312 Phosphoesterase GO:0016788 LH59_20210 9f34297e7df8fcf3fbe8bb9672c0a14a 580 SUPERFAMILY SSF53649 212 552 5.45E-22 T 14-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 LH59_20210 9f34297e7df8fcf3fbe8bb9672c0a14a 580 Gene3D G3DSA:3.40.720.10 76 285 8.4E-25 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 LH59_20210 9f34297e7df8fcf3fbe8bb9672c0a14a 580 Gene3D G3DSA:3.40.720.10 435 580 1.8E-35 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 LH59_20210 9f34297e7df8fcf3fbe8bb9672c0a14a 580 TIGRFAM TIGR03397 acid_phos_Burk: acid phosphatase, Burkholderia-type 85 579 2.3E-230 T 14-10-2018 IPR017768 Acid phosphatase, AcpA GO:0003993 LH59_22230 38e4a9b18a700f8341c11d34c9a44842 553 Pfam PF00378 Enoyl-CoA hydratase/isomerase 49 238 9.7E-23 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 LH59_22230 38e4a9b18a700f8341c11d34c9a44842 553 TIGRFAM TIGR03222 benzo_boxC: benzoyl-CoA-dihydrodiol lyase 8 553 2.6E-294 T 14-10-2018 IPR017633 Benzoyl-CoA-dihydrodiol lyase KEGG: 00362+4.1.2.44|MetaCyc: PWY-1361 LH59_22230 38e4a9b18a700f8341c11d34c9a44842 553 SUPERFAMILY SSF52096 15 280 5.2E-32 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily LH59_22230 38e4a9b18a700f8341c11d34c9a44842 553 SUPERFAMILY SSF52096 302 547 1.4E-16 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily LH59_22230 38e4a9b18a700f8341c11d34c9a44842 553 Gene3D G3DSA:3.90.226.10 8 553 1.4E-291 T 14-10-2018 LH59_22230 38e4a9b18a700f8341c11d34c9a44842 553 Gene3D G3DSA:3.90.226.10 259 488 1.4E-291 T 14-10-2018 LH59_17625 96de52b0be4512a48f7ef820795cd8e6 162 Gene3D G3DSA:1.10.1740.10 2 75 2.5E-7 T 14-10-2018 LH59_17625 96de52b0be4512a48f7ef820795cd8e6 162 Pfam PF08281 Sigma-70, region 4 105 156 5.0E-9 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LH59_17625 96de52b0be4512a48f7ef820795cd8e6 162 Gene3D G3DSA:1.10.10.10 78 162 2.1E-10 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_17625 96de52b0be4512a48f7ef820795cd8e6 162 SUPERFAMILY SSF88946 5 84 1.29E-13 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 LH59_17625 96de52b0be4512a48f7ef820795cd8e6 162 Pfam PF04542 Sigma-70 region 2 8 73 5.4E-8 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 LH59_17625 96de52b0be4512a48f7ef820795cd8e6 162 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 4 153 1.1E-19 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 LH59_17625 96de52b0be4512a48f7ef820795cd8e6 162 SUPERFAMILY SSF88659 97 156 1.1E-9 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like LH59_03875 cb762ecc9dea3baac2a89b9a9a5c3bd5 534 SUPERFAMILY SSF56235 6 534 4.79E-170 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal LH59_03875 cb762ecc9dea3baac2a89b9a9a5c3bd5 534 Pfam PF01019 Gamma-glutamyltranspeptidase 35 529 4.6E-150 T 14-10-2018 LH59_03875 cb762ecc9dea3baac2a89b9a9a5c3bd5 534 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 111 129 5.1E-37 T 14-10-2018 LH59_03875 cb762ecc9dea3baac2a89b9a9a5c3bd5 534 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 129 148 5.1E-37 T 14-10-2018 LH59_03875 cb762ecc9dea3baac2a89b9a9a5c3bd5 534 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 405 420 5.1E-37 T 14-10-2018 LH59_03875 cb762ecc9dea3baac2a89b9a9a5c3bd5 534 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 256 275 5.1E-37 T 14-10-2018 LH59_03875 cb762ecc9dea3baac2a89b9a9a5c3bd5 534 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 350 368 5.1E-37 T 14-10-2018 LH59_03875 cb762ecc9dea3baac2a89b9a9a5c3bd5 534 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 429 446 5.1E-37 T 14-10-2018 LH59_03875 cb762ecc9dea3baac2a89b9a9a5c3bd5 534 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 374 392 5.1E-37 T 14-10-2018 LH59_03875 cb762ecc9dea3baac2a89b9a9a5c3bd5 534 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 42 67 5.1E-37 T 14-10-2018 LH59_03875 cb762ecc9dea3baac2a89b9a9a5c3bd5 534 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 227 243 5.1E-37 T 14-10-2018 LH59_03875 cb762ecc9dea3baac2a89b9a9a5c3bd5 534 Gene3D G3DSA:1.10.246.130 243 354 5.5E-27 T 14-10-2018 LH59_03875 cb762ecc9dea3baac2a89b9a9a5c3bd5 534 Gene3D G3DSA:3.60.20.40 355 534 6.5E-65 T 14-10-2018 LH59_15260 95d5753c42de3773d6edbfcf3bb12cf2 137 SUPERFAMILY SSF54909 1 120 1.07E-30 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel LH59_15260 95d5753c42de3773d6edbfcf3bb12cf2 137 Pfam PF03795 YCII-related domain 1 113 7.5E-20 T 14-10-2018 IPR005545 YCII-related LH59_15260 95d5753c42de3773d6edbfcf3bb12cf2 137 Gene3D G3DSA:3.30.70.1060 1 119 1.1E-28 T 14-10-2018 LH59_08860 4edb5f2d560d92ee13e280dad8516639 195 Gene3D G3DSA:3.40.50.620 1 195 1.7E-54 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LH59_08860 4edb5f2d560d92ee13e280dad8516639 195 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 2 195 27.79 T 14-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 LH59_08860 4edb5f2d560d92ee13e280dad8516639 195 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 65 1.7E-8 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 LH59_08860 4edb5f2d560d92ee13e280dad8516639 195 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 6 194 1.5E-44 T 14-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 LH59_08860 4edb5f2d560d92ee13e280dad8516639 195 SUPERFAMILY SSF52374 2 195 9.38E-45 T 14-10-2018 LH59_08860 4edb5f2d560d92ee13e280dad8516639 195 Pfam PF01467 Cytidylyltransferase-like 6 169 8.0E-26 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 LH59_09740 1e12f9769fb41505fae17b31319e7767 305 Gene3D G3DSA:3.10.310.10 128 290 7.0E-73 T 14-10-2018 LH59_09740 1e12f9769fb41505fae17b31319e7767 305 PIRSF PIRSF016184 1 301 4.3E-73 T 14-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 LH59_09740 1e12f9769fb41505fae17b31319e7767 305 Gene3D G3DSA:3.10.310.10 7 292 7.0E-73 T 14-10-2018 LH59_09740 1e12f9769fb41505fae17b31319e7767 305 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 1 299 6.8E-57 T 14-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 LH59_09740 1e12f9769fb41505fae17b31319e7767 305 SUPERFAMILY SSF54506 1 299 6.7E-61 T 14-10-2018 LH59_09740 1e12f9769fb41505fae17b31319e7767 305 Pfam PF02567 Phenazine biosynthesis-like protein 9 297 3.7E-52 T 14-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 LH59_03980 ba9266f6420dfa2700ea9009db3872f0 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 3.0E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_03980 ba9266f6420dfa2700ea9009db3872f0 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 3.0E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_03980 ba9266f6420dfa2700ea9009db3872f0 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 3.0E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_03980 ba9266f6420dfa2700ea9009db3872f0 301 Gene3D G3DSA:3.40.190.10 101 284 1.8E-58 T 14-10-2018 LH59_03980 ba9266f6420dfa2700ea9009db3872f0 301 SUPERFAMILY SSF53850 91 292 2.28E-40 T 14-10-2018 LH59_03980 ba9266f6420dfa2700ea9009db3872f0 301 Gene3D G3DSA:1.10.10.10 6 95 2.1E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_03980 ba9266f6420dfa2700ea9009db3872f0 301 Gene3D G3DSA:3.40.190.10 160 257 1.8E-58 T 14-10-2018 LH59_03980 ba9266f6420dfa2700ea9009db3872f0 301 Pfam PF03466 LysR substrate binding domain 88 288 6.6E-39 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_03980 ba9266f6420dfa2700ea9009db3872f0 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 1.8E-20 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_03980 ba9266f6420dfa2700ea9009db3872f0 301 SUPERFAMILY SSF46785 2 87 3.56E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_25575 170064458db1716de1251a1223436995 198 Pfam PF06805 Bacteriophage lambda tail assembly protein I 7 89 4.6E-9 T 14-10-2018 IPR010654 Bacteriophage lambda tail assembly I LH59_10910 e60d0c10bee6168af6ac557aff295011 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 255 6.3E-52 T 14-10-2018 LH59_10910 e60d0c10bee6168af6ac557aff295011 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 3.2E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10910 e60d0c10bee6168af6ac557aff295011 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 3.2E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10910 e60d0c10bee6168af6ac557aff295011 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 3.2E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10910 e60d0c10bee6168af6ac557aff295011 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 202 3.2E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10910 e60d0c10bee6168af6ac557aff295011 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 3.2E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10910 e60d0c10bee6168af6ac557aff295011 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 5.4E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10910 e60d0c10bee6168af6ac557aff295011 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 152 5.4E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10910 e60d0c10bee6168af6ac557aff295011 258 SUPERFAMILY SSF51735 11 255 3.28E-65 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_10910 e60d0c10bee6168af6ac557aff295011 258 Gene3D G3DSA:3.40.50.720 4 257 5.1E-64 T 14-10-2018 LH59_18840 b86dcd890488ab24b634d74d03633574 232 SUPERFAMILY SSF47616 94 218 8.94E-12 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily LH59_18840 b86dcd890488ab24b634d74d03633574 232 Gene3D G3DSA:1.20.1050.10 92 225 6.6E-24 T 14-10-2018 LH59_18840 b86dcd890488ab24b634d74d03633574 232 Pfam PF13410 Glutathione S-transferase, C-terminal domain 149 215 1.1E-6 T 14-10-2018 LH59_18840 b86dcd890488ab24b634d74d03633574 232 Gene3D G3DSA:3.40.30.10 4 86 2.0E-15 T 14-10-2018 LH59_18840 b86dcd890488ab24b634d74d03633574 232 SUPERFAMILY SSF52833 16 110 5.18E-17 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_18840 b86dcd890488ab24b634d74d03633574 232 Pfam PF13417 Glutathione S-transferase, N-terminal domain 17 86 1.5E-11 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 LH59_16480 538c870372b7a1a629671ccd817af32d 220 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 70 2.3E-13 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_16480 538c870372b7a1a629671ccd817af32d 220 Gene3D G3DSA:1.10.357.10 21 210 1.1E-65 T 14-10-2018 LH59_16480 538c870372b7a1a629671ccd817af32d 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 1.7E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_16480 538c870372b7a1a629671ccd817af32d 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 1.7E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_16480 538c870372b7a1a629671ccd817af32d 220 SUPERFAMILY SSF46689 16 90 1.65E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_22550 ffab79259c265c021a50611ca7334a07 133 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 126 3.2E-6 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain LH59_22550 ffab79259c265c021a50611ca7334a07 133 Gene3D G3DSA:3.10.180.10 1 132 1.2E-34 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_22550 ffab79259c265c021a50611ca7334a07 133 SUPERFAMILY SSF54593 4 132 7.95E-21 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_02350 88a0497e617975ca15eb487e9b48b048 335 SUPERFAMILY SSF89733 3 331 4.84E-104 T 14-10-2018 IPR036111 Malate/L-sulfolactate/L-lactate dehydrogenase-like superfamily GO:0016491|GO:0055114 LH59_02350 88a0497e617975ca15eb487e9b48b048 335 Gene3D G3DSA:3.30.1370.60 62 301 2.2E-100 T 14-10-2018 LH59_02350 88a0497e617975ca15eb487e9b48b048 335 Gene3D G3DSA:1.10.1530.10 12 328 2.2E-100 T 14-10-2018 LH59_02350 88a0497e617975ca15eb487e9b48b048 335 Gene3D G3DSA:3.30.60.50 178 225 2.2E-100 T 14-10-2018 LH59_02350 88a0497e617975ca15eb487e9b48b048 335 Pfam PF02615 Malate/L-lactate dehydrogenase 6 328 5.3E-105 T 14-10-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0016491|GO:0055114 LH59_26150 f103d29c2730b6d00436f26d0e3580de 202 PIRSF PIRSF006324 1 201 1.1E-57 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 LH59_26150 f103d29c2730b6d00436f26d0e3580de 202 Pfam PF01810 LysE type translocator 16 199 2.9E-34 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 LH59_08970 4569a2b207d96184df95d1fdd23e75fb 224 Hamap MF_02089 Epoxyqueuosine reductase QueH [queH]. 18 194 33.257 T 14-10-2018 IPR003828 Epoxyqueuosine reductase QueH MetaCyc: PWY-6700 LH59_08970 4569a2b207d96184df95d1fdd23e75fb 224 Pfam PF02677 Uncharacterized BCR, COG1636 18 192 4.7E-65 T 14-10-2018 IPR003828 Epoxyqueuosine reductase QueH MetaCyc: PWY-6700 LH59_01200 d3c2390f2c22672b2d4fefc9a2f305d8 443 Gene3D G3DSA:1.20.1250.20 251 439 1.6E-19 T 14-10-2018 LH59_01200 d3c2390f2c22672b2d4fefc9a2f305d8 443 PRINTS PR01036 Tetracycline resistance protein TetB signature 390 409 4.3E-5 T 14-10-2018 LH59_01200 d3c2390f2c22672b2d4fefc9a2f305d8 443 PRINTS PR01036 Tetracycline resistance protein TetB signature 133 157 4.3E-5 T 14-10-2018 LH59_01200 d3c2390f2c22672b2d4fefc9a2f305d8 443 PRINTS PR01036 Tetracycline resistance protein TetB signature 12 36 4.3E-5 T 14-10-2018 LH59_01200 d3c2390f2c22672b2d4fefc9a2f305d8 443 PRINTS PR01036 Tetracycline resistance protein TetB signature 103 123 4.3E-5 T 14-10-2018 LH59_01200 d3c2390f2c22672b2d4fefc9a2f305d8 443 Pfam PF07690 Major Facilitator Superfamily 15 399 1.6E-45 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_01200 d3c2390f2c22672b2d4fefc9a2f305d8 443 Gene3D G3DSA:1.20.1720.10 11 239 3.1E-41 T 14-10-2018 LH59_01200 d3c2390f2c22672b2d4fefc9a2f305d8 443 SUPERFAMILY SSF103473 3 435 1.27E-61 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_21190 17a84bc922ef76bbae69512badf19114 609 SMART SM00465 17 98 6.8E-17 T 14-10-2018 IPR000305 GIY-YIG endonuclease LH59_21190 17a84bc922ef76bbae69512badf19114 609 Pfam PF02151 UvrB/uvrC motif 206 235 1.2E-6 T 14-10-2018 IPR001943 UVR domain GO:0005515 LH59_21190 17a84bc922ef76bbae69512badf19114 609 SUPERFAMILY SSF47781 521 608 3.18E-19 T 14-10-2018 IPR010994 RuvA domain 2-like LH59_21190 17a84bc922ef76bbae69512badf19114 609 SUPERFAMILY SSF46600 190 242 2.75E-12 T 14-10-2018 IPR036876 UVR domain superfamily LH59_21190 17a84bc922ef76bbae69512badf19114 609 Gene3D G3DSA:1.10.150.20 554 609 4.3E-21 T 14-10-2018 LH59_21190 17a84bc922ef76bbae69512badf19114 609 Pfam PF14520 Helix-hairpin-helix domain 556 608 1.3E-8 T 14-10-2018 LH59_21190 17a84bc922ef76bbae69512badf19114 609 SUPERFAMILY SSF82771 17 100 7.19E-22 T 14-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 LH59_21190 17a84bc922ef76bbae69512badf19114 609 Hamap MF_00203 UvrABC system protein C [uvrC]. 4 606 26.905 T 14-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 LH59_21190 17a84bc922ef76bbae69512badf19114 609 Gene3D G3DSA:3.30.420.340 379 541 2.1E-45 T 14-10-2018 IPR038476 UvrC homology region 2 superfamily LH59_21190 17a84bc922ef76bbae69512badf19114 609 SMART SM00278 587 606 0.065 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 LH59_21190 17a84bc922ef76bbae69512badf19114 609 SMART SM00278 555 574 15.0 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 LH59_21190 17a84bc922ef76bbae69512badf19114 609 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 7 588 6.9E-166 T 14-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 LH59_21190 17a84bc922ef76bbae69512badf19114 609 Pfam PF01541 GIY-YIG catalytic domain 19 93 7.1E-10 T 14-10-2018 IPR000305 GIY-YIG endonuclease LH59_21190 17a84bc922ef76bbae69512badf19114 609 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 394 541 8.7E-46 T 14-10-2018 IPR001162 UvrC family homology region LH59_21190 17a84bc922ef76bbae69512badf19114 609 Gene3D G3DSA:3.40.1440.10 4 102 4.8E-32 T 14-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 LH59_09970 fc423dbe3a965fba64d94988f5e1959a 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 3.8E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_09970 fc423dbe3a965fba64d94988f5e1959a 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 3.8E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_09970 fc423dbe3a965fba64d94988f5e1959a 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 3.8E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_09970 fc423dbe3a965fba64d94988f5e1959a 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 3.8E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_09970 fc423dbe3a965fba64d94988f5e1959a 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 3.8E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_09970 fc423dbe3a965fba64d94988f5e1959a 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 3.8E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_09970 fc423dbe3a965fba64d94988f5e1959a 243 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 242 3.1E-54 T 14-10-2018 LH59_09970 fc423dbe3a965fba64d94988f5e1959a 243 Gene3D G3DSA:3.40.50.720 4 243 6.0E-74 T 14-10-2018 LH59_09970 fc423dbe3a965fba64d94988f5e1959a 243 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 190 1.6E-5 T 14-10-2018 LH59_09970 fc423dbe3a965fba64d94988f5e1959a 243 TIGRFAM TIGR01831 fabG_rel: putative 3-oxoacyl-(acyl-carrier-protein) reductase 6 242 3.6E-115 T 14-10-2018 IPR011285 3-oxoacyl-(acyl-carrier-protein) reductase, putative KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 LH59_09970 fc423dbe3a965fba64d94988f5e1959a 243 SUPERFAMILY SSF51735 6 242 1.85E-70 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_09970 fc423dbe3a965fba64d94988f5e1959a 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 3.2E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_09970 fc423dbe3a965fba64d94988f5e1959a 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 3.2E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_09970 fc423dbe3a965fba64d94988f5e1959a 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 3.2E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_14010 8a4596dab4ec629c6b4806e377427096 526 Gene3D G3DSA:3.40.605.10 43 522 1.1E-202 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 LH59_14010 8a4596dab4ec629c6b4806e377427096 526 SUPERFAMILY SSF53720 20 520 7.72E-97 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 LH59_14010 8a4596dab4ec629c6b4806e377427096 526 Gene3D G3DSA:3.40.309.10 268 457 1.1E-202 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 LH59_14010 8a4596dab4ec629c6b4806e377427096 526 Pfam PF00171 Aldehyde dehydrogenase family 20 469 1.6E-45 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 LH59_23550 a4c6f793fbd6eedeea43e9127d9e2ccd 329 PIRSF PIRSF018266 1 319 1.2E-95 T 14-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component LH59_23550 a4c6f793fbd6eedeea43e9127d9e2ccd 329 Pfam PF04773 FecR protein 112 207 4.4E-18 T 14-10-2018 IPR006860 FecR protein LH59_23550 a4c6f793fbd6eedeea43e9127d9e2ccd 329 Gene3D G3DSA:2.60.120.1440 105 242 2.0E-19 T 14-10-2018 LH59_23550 a4c6f793fbd6eedeea43e9127d9e2ccd 329 Pfam PF16220 Domain of unknown function (DUF4880) 11 53 9.0E-13 T 14-10-2018 IPR032623 FecR, N-terminal LH59_23010 b829d9b760733f2e23f87e12865f1e43 435 Gene3D G3DSA:2.120.10.30 161 420 7.0E-12 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like LH59_23010 b829d9b760733f2e23f87e12865f1e43 435 Pfam PF07995 Glucose / Sorbosone dehydrogenase 167 347 9.1E-9 T 14-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase LH59_23010 b829d9b760733f2e23f87e12865f1e43 435 SUPERFAMILY SSF50952 58 430 1.15E-36 T 14-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 LH59_06690 66f5dc8143c75f2197e25e2834255064 426 Gene3D G3DSA:3.40.640.10 48 328 1.5E-150 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_06690 66f5dc8143c75f2197e25e2834255064 426 Gene3D G3DSA:3.90.1150.10 11 417 1.5E-150 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_06690 66f5dc8143c75f2197e25e2834255064 426 Pfam PF00202 Aminotransferase class-III 9 422 3.8E-93 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LH59_06690 66f5dc8143c75f2197e25e2834255064 426 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 236 273 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LH59_06690 66f5dc8143c75f2197e25e2834255064 426 SUPERFAMILY SSF53383 6 422 5.45E-122 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_06690 66f5dc8143c75f2197e25e2834255064 426 PIRSF PIRSF000521 170 424 3.8E-19 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LH59_06690 66f5dc8143c75f2197e25e2834255064 426 PIRSF PIRSF000521 14 132 1.1E-6 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LH59_17075 3ee38de59fc302cdb5c643e1de830789 332 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 2 332 35.82 T 14-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 LH59_17075 3ee38de59fc302cdb5c643e1de830789 332 SUPERFAMILY SSF75620 4 329 3.01E-129 T 14-10-2018 LH59_17075 3ee38de59fc302cdb5c643e1de830789 332 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 3 330 3.1E-149 T 14-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 LH59_17075 3ee38de59fc302cdb5c643e1de830789 332 Pfam PF00472 RF-1 domain 196 304 1.7E-41 T 14-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 LH59_17075 3ee38de59fc302cdb5c643e1de830789 332 SMART SM00937 52 162 7.7E-54 T 14-10-2018 IPR005139 Peptide chain release factor GO:0006415 LH59_17075 3ee38de59fc302cdb5c643e1de830789 332 Gene3D G3DSA:1.20.58.410 1 83 6.6E-20 T 14-10-2018 LH59_17075 3ee38de59fc302cdb5c643e1de830789 332 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 212 228 - T 14-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 LH59_17075 3ee38de59fc302cdb5c643e1de830789 332 Gene3D G3DSA:3.30.70.1660 97 325 3.9E-98 T 14-10-2018 LH59_17075 3ee38de59fc302cdb5c643e1de830789 332 Gene3D G3DSA:3.30.160.20 193 288 3.9E-98 T 14-10-2018 LH59_17075 3ee38de59fc302cdb5c643e1de830789 332 Pfam PF03462 PCRF domain 3 187 4.3E-54 T 14-10-2018 IPR005139 Peptide chain release factor GO:0006415 LH59_11465 f4db6f249b067a9d834ff3be620c708a 531 SUPERFAMILY SSF58104 246 527 2.75E-70 T 14-10-2018 LH59_11465 f4db6f249b067a9d834ff3be620c708a 531 Gene3D G3DSA:1.10.287.950 226 528 2.8E-83 T 14-10-2018 LH59_11465 f4db6f249b067a9d834ff3be620c708a 531 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 338 493 3.2E-52 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 LH59_11465 f4db6f249b067a9d834ff3be620c708a 531 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 23 113 2.7E-16 T 14-10-2018 IPR000014 PAS domain LH59_11465 f4db6f249b067a9d834ff3be620c708a 531 SUPERFAMILY SSF55785 20 114 1.59E-28 T 14-10-2018 IPR035965 PAS domain superfamily LH59_11465 f4db6f249b067a9d834ff3be620c708a 531 Pfam PF08447 PAS fold 30 113 2.1E-16 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 LH59_11465 f4db6f249b067a9d834ff3be620c708a 531 SMART SM00283 279 526 1.0E-80 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 LH59_11465 f4db6f249b067a9d834ff3be620c708a 531 Pfam PF00672 HAMP domain 226 274 3.4E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_11465 f4db6f249b067a9d834ff3be620c708a 531 Gene3D G3DSA:3.30.450.20 11 142 1.7E-26 T 14-10-2018 LH59_11465 f4db6f249b067a9d834ff3be620c708a 531 SMART SM00091 8 74 0.0014 T 14-10-2018 IPR000014 PAS domain LH59_11465 f4db6f249b067a9d834ff3be620c708a 531 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 377 404 2.4E-56 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_11465 f4db6f249b067a9d834ff3be620c708a 531 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 406 435 2.4E-56 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_11465 f4db6f249b067a9d834ff3be620c708a 531 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 454 483 2.4E-56 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_11465 f4db6f249b067a9d834ff3be620c708a 531 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 300 329 2.4E-56 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_11465 f4db6f249b067a9d834ff3be620c708a 531 SMART SM00304 226 278 1.1E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_11465 f4db6f249b067a9d834ff3be620c708a 531 SMART SM00086 80 121 0.0024 T 14-10-2018 IPR001610 PAC motif LH59_20875 f8a4c2f531c4a1ac5e0d6f2839620caf 446 Pfam PF13180 PDZ domain 259 342 4.3E-13 T 14-10-2018 IPR001478 PDZ domain GO:0005515 LH59_20875 f8a4c2f531c4a1ac5e0d6f2839620caf 446 Pfam PF13180 PDZ domain 378 445 5.2E-7 T 14-10-2018 IPR001478 PDZ domain GO:0005515 LH59_20875 f8a4c2f531c4a1ac5e0d6f2839620caf 446 SUPERFAMILY SSF50494 37 249 2.7E-63 T 14-10-2018 IPR009003 Peptidase S1, PA clan LH59_20875 f8a4c2f531c4a1ac5e0d6f2839620caf 446 Pfam PF13365 Trypsin-like peptidase domain 78 213 6.5E-33 T 14-10-2018 LH59_20875 f8a4c2f531c4a1ac5e0d6f2839620caf 446 Gene3D G3DSA:2.40.10.120 37 246 1.5E-79 T 14-10-2018 LH59_20875 f8a4c2f531c4a1ac5e0d6f2839620caf 446 SUPERFAMILY SSF50156 373 445 5.65E-9 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 LH59_20875 f8a4c2f531c4a1ac5e0d6f2839620caf 446 Gene3D G3DSA:2.30.42.10 247 353 5.8E-24 T 14-10-2018 LH59_20875 f8a4c2f531c4a1ac5e0d6f2839620caf 446 SMART SM00228 355 438 0.12 T 14-10-2018 IPR001478 PDZ domain GO:0005515 LH59_20875 f8a4c2f531c4a1ac5e0d6f2839620caf 446 SMART SM00228 252 335 1.3E-10 T 14-10-2018 IPR001478 PDZ domain GO:0005515 LH59_20875 f8a4c2f531c4a1ac5e0d6f2839620caf 446 Gene3D G3DSA:2.30.42.10 358 446 1.3E-11 T 14-10-2018 LH59_20875 f8a4c2f531c4a1ac5e0d6f2839620caf 446 SUPERFAMILY SSF50156 234 343 1.58E-20 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 LH59_20875 f8a4c2f531c4a1ac5e0d6f2839620caf 446 PRINTS PR00834 HtrA/DegQ protease family signature 149 173 2.1E-51 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 LH59_20875 f8a4c2f531c4a1ac5e0d6f2839620caf 446 PRINTS PR00834 HtrA/DegQ protease family signature 184 201 2.1E-51 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 LH59_20875 f8a4c2f531c4a1ac5e0d6f2839620caf 446 PRINTS PR00834 HtrA/DegQ protease family signature 88 100 2.1E-51 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 LH59_20875 f8a4c2f531c4a1ac5e0d6f2839620caf 446 PRINTS PR00834 HtrA/DegQ protease family signature 109 129 2.1E-51 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 LH59_20875 f8a4c2f531c4a1ac5e0d6f2839620caf 446 PRINTS PR00834 HtrA/DegQ protease family signature 293 305 2.1E-51 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 LH59_20875 f8a4c2f531c4a1ac5e0d6f2839620caf 446 PRINTS PR00834 HtrA/DegQ protease family signature 206 223 2.1E-51 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 LH59_25990 efda1a722bffc28c78b946b45a7d9eb4 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 157 1.2E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25990 efda1a722bffc28c78b946b45a7d9eb4 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 206 1.2E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25990 efda1a722bffc28c78b946b45a7d9eb4 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 1.2E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25990 efda1a722bffc28c78b946b45a7d9eb4 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 187 1.2E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25990 efda1a722bffc28c78b946b45a7d9eb4 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 1.2E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25990 efda1a722bffc28c78b946b45a7d9eb4 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 244 1.2E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25990 efda1a722bffc28c78b946b45a7d9eb4 263 Gene3D G3DSA:3.40.50.720 6 263 1.3E-71 T 14-10-2018 LH59_25990 efda1a722bffc28c78b946b45a7d9eb4 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 24 260 4.1E-56 T 14-10-2018 LH59_25990 efda1a722bffc28c78b946b45a7d9eb4 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 155 4.0E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25990 efda1a722bffc28c78b946b45a7d9eb4 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 168 187 4.0E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25990 efda1a722bffc28c78b946b45a7d9eb4 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 4.0E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25990 efda1a722bffc28c78b946b45a7d9eb4 263 SUPERFAMILY SSF51735 14 262 1.74E-72 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_14405 5e59a47443ca894d3efb96b452bbfe15 236 Gene3D G3DSA:3.50.30.100 2 201 1.7E-52 T 14-10-2018 LH59_14405 5e59a47443ca894d3efb96b452bbfe15 236 SUPERFAMILY SSF89562 12 190 3.4E-43 T 14-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily LH59_14405 5e59a47443ca894d3efb96b452bbfe15 236 Pfam PF03737 Aldolase/RraA 14 179 3.3E-33 T 14-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein LH59_11370 85b615248590ebf0649663683e27c63a 706 Pfam PF00771 FHIPEP family 28 691 5.4E-271 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 LH59_11370 85b615248590ebf0649663683e27c63a 706 TIGRFAM TIGR01398 FlhA: flagellar biosynthesis protein FlhA 20 700 8.2E-272 T 14-10-2018 IPR006301 Flagellar biosynthesis protein FlhA GO:0016021|GO:0044780 LH59_11370 85b615248590ebf0649663683e27c63a 706 Gene3D G3DSA:1.10.490.80 607 700 4.5E-9 T 14-10-2018 LH59_11370 85b615248590ebf0649663683e27c63a 706 Gene3D G3DSA:1.10.8.540 505 604 1.7E-22 T 14-10-2018 LH59_11370 85b615248590ebf0649663683e27c63a 706 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 35 48 3.5E-56 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 LH59_11370 85b615248590ebf0649663683e27c63a 706 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 139 155 3.5E-56 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 LH59_11370 85b615248590ebf0649663683e27c63a 706 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 188 205 3.5E-56 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 LH59_11370 85b615248590ebf0649663683e27c63a 706 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 72 91 3.5E-56 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 LH59_11370 85b615248590ebf0649663683e27c63a 706 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 158 176 3.5E-56 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 LH59_11370 85b615248590ebf0649663683e27c63a 706 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 239 253 3.5E-56 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 LH59_11370 85b615248590ebf0649663683e27c63a 706 ProSitePatterns PS00994 Bacterial export FHIPEP family signature. 144 167 - T 14-10-2018 IPR025505 FHIPEP conserved site LH59_11370 85b615248590ebf0649663683e27c63a 706 PIRSF PIRSF005419 2 704 4.6E-245 T 14-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 LH59_11370 85b615248590ebf0649663683e27c63a 706 Gene3D G3DSA:3.40.30.60 362 504 2.6E-50 T 14-10-2018 LH59_27165 9f92e3fc1f32c036515bb936845899ed 240 SUPERFAMILY SSF52540 7 225 8.81E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_27165 9f92e3fc1f32c036515bb936845899ed 240 Gene3D G3DSA:3.40.50.300 2 238 2.9E-56 T 14-10-2018 LH59_27165 9f92e3fc1f32c036515bb936845899ed 240 Pfam PF00005 ABC transporter 23 164 4.8E-23 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_27165 9f92e3fc1f32c036515bb936845899ed 240 SMART SM00382 32 213 3.2E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_02640 572758c53f5fb86de7c776b372bd4891 338 SMART SM00062 34 263 2.7E-47 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_02640 572758c53f5fb86de7c776b372bd4891 338 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 35 253 1.0E-33 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_02640 572758c53f5fb86de7c776b372bd4891 338 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 57 70 - T 14-10-2018 IPR018313 Solute-binding protein family 3, conserved site LH59_02640 572758c53f5fb86de7c776b372bd4891 338 Gene3D G3DSA:3.40.190.10 29 241 2.9E-52 T 14-10-2018 LH59_02640 572758c53f5fb86de7c776b372bd4891 338 SUPERFAMILY SSF53850 25 256 6.22E-50 T 14-10-2018 LH59_02640 572758c53f5fb86de7c776b372bd4891 338 Gene3D G3DSA:3.40.190.10 121 226 2.9E-52 T 14-10-2018 LH59_18030 f2e38e3706f784829bd0cc8945663c7a 333 Gene3D G3DSA:3.40.190.150 33 323 2.1E-113 T 14-10-2018 LH59_18030 f2e38e3706f784829bd0cc8945663c7a 333 PIRSF PIRSF017082 3 332 5.2E-81 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_18030 f2e38e3706f784829bd0cc8945663c7a 333 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 328 4.1E-83 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_18030 f2e38e3706f784829bd0cc8945663c7a 333 Gene3D G3DSA:3.40.190.10 131 258 2.1E-113 T 14-10-2018 LH59_18030 f2e38e3706f784829bd0cc8945663c7a 333 SUPERFAMILY SSF53850 121 287 3.86E-11 T 14-10-2018 LH59_08050 864d4009a84c55561d6dd527bd2cd3aa 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 9.2E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_08050 864d4009a84c55561d6dd527bd2cd3aa 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 9.2E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_08050 864d4009a84c55561d6dd527bd2cd3aa 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 9.2E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_08050 864d4009a84c55561d6dd527bd2cd3aa 254 Gene3D G3DSA:3.40.50.720 5 254 8.3E-83 T 14-10-2018 LH59_08050 864d4009a84c55561d6dd527bd2cd3aa 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LH59_08050 864d4009a84c55561d6dd527bd2cd3aa 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 9.5E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_08050 864d4009a84c55561d6dd527bd2cd3aa 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 9.5E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_08050 864d4009a84c55561d6dd527bd2cd3aa 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 9.5E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_08050 864d4009a84c55561d6dd527bd2cd3aa 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 9.5E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_08050 864d4009a84c55561d6dd527bd2cd3aa 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 9.5E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_08050 864d4009a84c55561d6dd527bd2cd3aa 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 9.5E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_08050 864d4009a84c55561d6dd527bd2cd3aa 254 SUPERFAMILY SSF51735 11 253 7.11E-80 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_08050 864d4009a84c55561d6dd527bd2cd3aa 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 252 6.5E-65 T 14-10-2018 LH59_04070 e0b00b57f5b446cf73a6eee9e113ab4a 394 Gene3D G3DSA:3.40.50.1440 13 316 3.2E-108 T 14-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 LH59_04070 e0b00b57f5b446cf73a6eee9e113ab4a 394 SMART SM00865 206 324 1.3E-53 T 14-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 LH59_04070 e0b00b57f5b446cf73a6eee9e113ab4a 394 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 11 379 34.561 T 14-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 LH59_04070 e0b00b57f5b446cf73a6eee9e113ab4a 394 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 7 325 1.1E-115 T 14-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 LH59_04070 e0b00b57f5b446cf73a6eee9e113ab4a 394 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 16 172 1.4E-34 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 LH59_04070 e0b00b57f5b446cf73a6eee9e113ab4a 394 SUPERFAMILY SSF52490 15 207 2.88E-61 T 14-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 LH59_04070 e0b00b57f5b446cf73a6eee9e113ab4a 394 Pfam PF12327 FtsZ family, C-terminal domain 221 315 2.9E-32 T 14-10-2018 IPR024757 Cell division protein FtsZ, C-terminal LH59_04070 e0b00b57f5b446cf73a6eee9e113ab4a 394 SMART SM00864 15 204 3.1E-101 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 LH59_04070 e0b00b57f5b446cf73a6eee9e113ab4a 394 SUPERFAMILY SSF55307 206 322 5.49E-40 T 14-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 LH59_04070 e0b00b57f5b446cf73a6eee9e113ab4a 394 PRINTS PR00423 Cell division protein FtsZ signature 97 117 9.3E-46 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 LH59_04070 e0b00b57f5b446cf73a6eee9e113ab4a 394 PRINTS PR00423 Cell division protein FtsZ signature 211 232 9.3E-46 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 LH59_04070 e0b00b57f5b446cf73a6eee9e113ab4a 394 PRINTS PR00423 Cell division protein FtsZ signature 125 146 9.3E-46 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 LH59_04070 e0b00b57f5b446cf73a6eee9e113ab4a 394 PRINTS PR00423 Cell division protein FtsZ signature 188 210 9.3E-46 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 LH59_14350 ca2e98dec7befd0b81cb5acfc6f38f4d 202 Gene3D G3DSA:3.40.50.150 7 197 4.5E-35 T 14-10-2018 LH59_14350 ca2e98dec7befd0b81cb5acfc6f38f4d 202 SUPERFAMILY SSF53335 11 188 9.71E-32 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_14350 ca2e98dec7befd0b81cb5acfc6f38f4d 202 Pfam PF13649 Methyltransferase domain 48 137 9.3E-16 T 14-10-2018 LH59_24705 82e3d4e0ddb68550eeffafaf256914bb 381 Gene3D G3DSA:3.40.50.2000 9 189 1.2E-22 T 14-10-2018 LH59_24705 82e3d4e0ddb68550eeffafaf256914bb 381 Gene3D G3DSA:3.40.50.2000 194 364 3.0E-43 T 14-10-2018 LH59_24705 82e3d4e0ddb68550eeffafaf256914bb 381 SUPERFAMILY SSF53756 12 374 8.9E-79 T 14-10-2018 LH59_24705 82e3d4e0ddb68550eeffafaf256914bb 381 Pfam PF13439 Glycosyltransferase Family 4 23 181 2.5E-21 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 LH59_24705 82e3d4e0ddb68550eeffafaf256914bb 381 Pfam PF00534 Glycosyl transferases group 1 196 354 2.2E-35 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 LH59_11800 b754b3a812492e750f537285e9f77611 229 Pfam PF01988 VIT family 15 222 4.6E-54 T 14-10-2018 IPR008217 Ccc1 family LH59_10520 933d9f85ef9d32c51d209cbd51b50e56 210 Pfam PF03264 NapC/NirT cytochrome c family, N-terminal region 15 188 4.7E-76 T 14-10-2018 IPR005126 NapC/NirT cytochrome c, N-terminal LH59_10520 933d9f85ef9d32c51d209cbd51b50e56 210 TIGRFAM TIGR02161 napC_nirT: periplasmic nitrate (or nitrite) reductase c-type cytochrome, NapC/NirT family 5 188 6.0E-99 T 14-10-2018 IPR011885 Periplasmic nitrate reductase c-type cytochrome, NapC/NirT GO:0016021|GO:0019333|GO:0020037 LH59_10520 933d9f85ef9d32c51d209cbd51b50e56 210 Gene3D G3DSA:1.10.3820.10 16 190 1.5E-36 T 14-10-2018 IPR038266 NapC/NirT cytochrome c superfamily LH59_10520 933d9f85ef9d32c51d209cbd51b50e56 210 PIRSF PIRSF000013 1 196 1.6E-104 T 14-10-2018 IPR024717 Denitrification system component NapC/NirT/NrfH GO:0016021|GO:0019333|GO:0020037 LH59_10520 933d9f85ef9d32c51d209cbd51b50e56 210 SUPERFAMILY SSF48695 12 189 6.71E-63 T 14-10-2018 IPR036280 Multiheme cytochrome superfamily LH59_08465 61a1faa806b32d5b90cb507c02dba147 147 Pfam PF13673 Acetyltransferase (GNAT) domain 48 145 6.0E-21 T 14-10-2018 IPR000182 GNAT domain LH59_08465 61a1faa806b32d5b90cb507c02dba147 147 SUPERFAMILY SSF55729 8 145 9.04E-37 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_08465 61a1faa806b32d5b90cb507c02dba147 147 Gene3D G3DSA:3.40.630.30 13 147 8.0E-39 T 14-10-2018 LH59_18025 80f8480dc0a15f24b38eaf549a60a87a 309 Gene3D G3DSA:3.20.20.70 9 304 6.2E-25 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_18025 80f8480dc0a15f24b38eaf549a60a87a 309 SUPERFAMILY SSF51569 14 299 6.91E-29 T 14-10-2018 LH59_18025 80f8480dc0a15f24b38eaf549a60a87a 309 SMART SM01130 11 303 5.5E-7 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_03795 82bd89b830b13a1846735d48e036610e 166 Pfam PF00691 OmpA family 63 158 2.0E-21 T 14-10-2018 IPR006665 OmpA-like domain LH59_03795 82bd89b830b13a1846735d48e036610e 166 ProSitePatterns PS01068 OmpA-like domain. 96 140 - T 14-10-2018 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 LH59_03795 82bd89b830b13a1846735d48e036610e 166 Hamap MF_02204 Peptidoglycan-associated lipoprotein [pal]. 4 164 30.069 T 14-10-2018 IPR039001 Peptidoglycan-associated lipoprotein GO:0009279|GO:0051301 LH59_03795 82bd89b830b13a1846735d48e036610e 166 Gene3D G3DSA:3.30.1330.60 47 166 4.2E-36 T 14-10-2018 IPR036737 OmpA-like domain superfamily LH59_03795 82bd89b830b13a1846735d48e036610e 166 SUPERFAMILY SSF103088 55 164 5.89E-32 T 14-10-2018 IPR036737 OmpA-like domain superfamily LH59_03795 82bd89b830b13a1846735d48e036610e 166 PRINTS PR01021 OMPA domain signature 64 86 2.2E-13 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 LH59_03795 82bd89b830b13a1846735d48e036610e 166 PRINTS PR01021 OMPA domain signature 94 109 2.2E-13 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 LH59_03795 82bd89b830b13a1846735d48e036610e 166 PRINTS PR01021 OMPA domain signature 109 125 2.2E-13 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 LH59_03795 82bd89b830b13a1846735d48e036610e 166 TIGRFAM TIGR02802 Pal_lipo: peptidoglycan-associated lipoprotein 61 164 2.9E-41 T 14-10-2018 IPR014169 Peptidoglycan-associated lipoprotein, C-terminal GO:0009279 LH59_08595 6be84f4239923909798149874c95e614 96 Gene3D G3DSA:3.30.70.2340 1 96 1.5E-35 T 14-10-2018 LH59_08595 6be84f4239923909798149874c95e614 96 Pfam PF12112 Protein of unknown function (DUF3579) 5 93 5.3E-38 T 14-10-2018 IPR021969 Protein of unknown function DUF3579 LH59_19900 6b56f56c8cc83164090aebdc5c17de29 489 Pfam PF00155 Aminotransferase class I and II 141 439 6.2E-23 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LH59_19900 6b56f56c8cc83164090aebdc5c17de29 489 Gene3D G3DSA:1.10.10.10 1 90 7.1E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_19900 6b56f56c8cc83164090aebdc5c17de29 489 SUPERFAMILY SSF46785 4 68 1.99E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_19900 6b56f56c8cc83164090aebdc5c17de29 489 SMART SM00345 5 64 4.7E-10 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_19900 6b56f56c8cc83164090aebdc5c17de29 489 Pfam PF00392 Bacterial regulatory proteins, gntR family 3 64 7.5E-12 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_19900 6b56f56c8cc83164090aebdc5c17de29 489 SUPERFAMILY SSF53383 111 472 2.48E-81 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_19900 6b56f56c8cc83164090aebdc5c17de29 489 Gene3D G3DSA:3.40.640.10 99 465 4.0E-114 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_18510 529eb343b06aa92200c87ae4bcdfca4d 295 Gene3D G3DSA:3.40.190.10 163 270 4.2E-48 T 14-10-2018 LH59_18510 529eb343b06aa92200c87ae4bcdfca4d 295 Gene3D G3DSA:3.40.190.10 91 285 4.2E-48 T 14-10-2018 LH59_18510 529eb343b06aa92200c87ae4bcdfca4d 295 SUPERFAMILY SSF46785 1 111 6.13E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_18510 529eb343b06aa92200c87ae4bcdfca4d 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 4.7E-21 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_18510 529eb343b06aa92200c87ae4bcdfca4d 295 SUPERFAMILY SSF53850 89 284 1.0E-33 T 14-10-2018 LH59_18510 529eb343b06aa92200c87ae4bcdfca4d 295 Pfam PF03466 LysR substrate binding domain 87 288 3.9E-34 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_18510 529eb343b06aa92200c87ae4bcdfca4d 295 Gene3D G3DSA:1.10.10.10 1 90 4.1E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_18510 529eb343b06aa92200c87ae4bcdfca4d 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.3E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_18510 529eb343b06aa92200c87ae4bcdfca4d 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.3E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_18510 529eb343b06aa92200c87ae4bcdfca4d 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.3E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_13585 f8fccb147e642ede160626e0c3a43ad2 312 SUPERFAMILY SSF52317 2 151 1.05E-42 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_13585 f8fccb147e642ede160626e0c3a43ad2 312 Pfam PF02016 LD-carboxypeptidase 10 297 5.7E-77 T 14-10-2018 IPR003507 Peptidase family S66 LH59_13585 f8fccb147e642ede160626e0c3a43ad2 312 Gene3D G3DSA:3.50.30.60 162 311 5.3E-41 T 14-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily LH59_13585 f8fccb147e642ede160626e0c3a43ad2 312 PIRSF PIRSF028757 1 311 1.1E-78 T 14-10-2018 IPR003507 Peptidase family S66 LH59_13585 f8fccb147e642ede160626e0c3a43ad2 312 Gene3D G3DSA:3.40.50.10740 3 155 5.6E-50 T 14-10-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal LH59_13585 f8fccb147e642ede160626e0c3a43ad2 312 SUPERFAMILY SSF141986 169 302 1.28E-36 T 14-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily LH59_12525 f41b72432215a592ff55fcf3701fb1a9 268 Pfam PF07286 Protein of unknown function (DUF1445) 117 259 8.7E-68 T 14-10-2018 IPR009906 D-glutamate cyclase LH59_12525 f41b72432215a592ff55fcf3701fb1a9 268 Hamap MF_01830 Putative hydro-lyase . 13 267 55.56 T 14-10-2018 IPR016938 Uncharacterised protein family UPF0317 LH59_12525 f41b72432215a592ff55fcf3701fb1a9 268 Gene3D G3DSA:3.40.1640.10 1 131 4.0E-48 T 14-10-2018 LH59_12525 f41b72432215a592ff55fcf3701fb1a9 268 PIRSF PIRSF029755 3 268 3.9E-125 T 14-10-2018 IPR016938 Uncharacterised protein family UPF0317 LH59_12525 f41b72432215a592ff55fcf3701fb1a9 268 SUPERFAMILY SSF160920 14 260 1.83E-115 T 14-10-2018 IPR038021 Putative hydro-lyase LH59_12525 f41b72432215a592ff55fcf3701fb1a9 268 Gene3D G3DSA:3.30.2040.10 132 239 1.2E-49 T 14-10-2018 LH59_06545 86d32132e6ef4cf4aab5089707ae5734 597 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 42 57 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site LH59_06545 86d32132e6ef4cf4aab5089707ae5734 597 Gene3D G3DSA:3.30.70.3380 368 478 3.4E-43 T 14-10-2018 LH59_06545 86d32132e6ef4cf4aab5089707ae5734 597 SUPERFAMILY SSF54980 292 370 9.35E-19 T 14-10-2018 IPR035647 EF-G domain III/V-like LH59_06545 86d32132e6ef4cf4aab5089707ae5734 597 Pfam PF00009 Elongation factor Tu GTP binding domain 3 181 8.3E-53 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_06545 86d32132e6ef4cf4aab5089707ae5734 597 Gene3D G3DSA:3.40.50.300 1 185 8.7E-72 T 14-10-2018 LH59_06545 86d32132e6ef4cf4aab5089707ae5734 597 Gene3D G3DSA:3.30.70.870 286 367 8.6E-36 T 14-10-2018 LH59_06545 86d32132e6ef4cf4aab5089707ae5734 597 Pfam PF06421 GTP-binding protein LepA C-terminus 487 593 3.4E-48 T 14-10-2018 IPR013842 GTP-binding protein LepA, C-terminal LH59_06545 86d32132e6ef4cf4aab5089707ae5734 597 Pfam PF03144 Elongation factor Tu domain 2 205 275 4.5E-10 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 LH59_06545 86d32132e6ef4cf4aab5089707ae5734 597 SMART SM00838 398 486 0.0011 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like LH59_06545 86d32132e6ef4cf4aab5089707ae5734 597 Gene3D G3DSA:2.40.30.10 186 285 6.4E-33 T 14-10-2018 LH59_06545 86d32132e6ef4cf4aab5089707ae5734 597 SUPERFAMILY SSF52540 2 205 5.61E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_06545 86d32132e6ef4cf4aab5089707ae5734 597 Pfam PF00679 Elongation factor G C-terminus 399 479 3.5E-22 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like LH59_06545 86d32132e6ef4cf4aab5089707ae5734 597 Gene3D G3DSA:3.30.70.2570 479 553 2.7E-30 T 14-10-2018 IPR038363 LepA, C-terminal domain superfamily LH59_06545 86d32132e6ef4cf4aab5089707ae5734 597 TIGRFAM TIGR01393 lepA: elongation factor 4 3 595 5.2E-297 T 14-10-2018 IPR006297 Elongation factor 4 GO:0005525 LH59_06545 86d32132e6ef4cf4aab5089707ae5734 597 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 6 176 1.5E-19 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 LH59_06545 86d32132e6ef4cf4aab5089707ae5734 597 PRINTS PR00315 GTP-binding elongation factor signature 6 19 2.4E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_06545 86d32132e6ef4cf4aab5089707ae5734 597 PRINTS PR00315 GTP-binding elongation factor signature 90 101 2.4E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_06545 86d32132e6ef4cf4aab5089707ae5734 597 PRINTS PR00315 GTP-binding elongation factor signature 74 84 2.4E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_06545 86d32132e6ef4cf4aab5089707ae5734 597 PRINTS PR00315 GTP-binding elongation factor signature 126 135 2.4E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_06545 86d32132e6ef4cf4aab5089707ae5734 597 PRINTS PR00315 GTP-binding elongation factor signature 49 57 2.4E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_06545 86d32132e6ef4cf4aab5089707ae5734 597 SUPERFAMILY SSF50447 165 288 1.1E-29 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily LH59_06545 86d32132e6ef4cf4aab5089707ae5734 597 Hamap MF_00071 Elongation factor 4 [lepA]. 1 597 300.951 T 14-10-2018 IPR006297 Elongation factor 4 GO:0005525 LH59_06545 86d32132e6ef4cf4aab5089707ae5734 597 SUPERFAMILY SSF54980 399 493 1.34E-26 T 14-10-2018 IPR035647 EF-G domain III/V-like LH59_27275 f56495cc4efaa76a8382df8a62e57e27 268 Pfam PF03309 Type III pantothenate kinase 2 201 2.2E-48 T 14-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 LH59_27275 f56495cc4efaa76a8382df8a62e57e27 268 SUPERFAMILY SSF53067 123 230 3.63E-22 T 14-10-2018 LH59_27275 f56495cc4efaa76a8382df8a62e57e27 268 SUPERFAMILY SSF53067 1 116 3.95E-20 T 14-10-2018 LH59_27275 f56495cc4efaa76a8382df8a62e57e27 268 Gene3D G3DSA:3.30.420.490 124 229 8.8E-55 T 14-10-2018 LH59_27275 f56495cc4efaa76a8382df8a62e57e27 268 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 264 15.137 T 14-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 LH59_27275 f56495cc4efaa76a8382df8a62e57e27 268 Gene3D G3DSA:3.30.420.40 3 123 8.8E-55 T 14-10-2018 LH59_05625 704ae682f26aa22ab42d32ea338f699e 260 SUPERFAMILY SSF51735 3 259 1.68E-77 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_05625 704ae682f26aa22ab42d32ea338f699e 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LH59_05625 704ae682f26aa22ab42d32ea338f699e 260 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 5 259 1.3E-105 T 14-10-2018 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 LH59_05625 704ae682f26aa22ab42d32ea338f699e 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 258 1.1E-57 T 14-10-2018 LH59_05625 704ae682f26aa22ab42d32ea338f699e 260 Gene3D G3DSA:3.40.50.720 1 260 7.6E-83 T 14-10-2018 LH59_05625 704ae682f26aa22ab42d32ea338f699e 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 2.1E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_05625 704ae682f26aa22ab42d32ea338f699e 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 2.1E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_05625 704ae682f26aa22ab42d32ea338f699e 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 2.1E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_05625 704ae682f26aa22ab42d32ea338f699e 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 7.2E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_05625 704ae682f26aa22ab42d32ea338f699e 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 7.2E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_05625 704ae682f26aa22ab42d32ea338f699e 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 7.2E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_05625 704ae682f26aa22ab42d32ea338f699e 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 7.2E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_05625 704ae682f26aa22ab42d32ea338f699e 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 7.2E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_05625 704ae682f26aa22ab42d32ea338f699e 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 7.2E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_00885 63115943bd771fa852c241e4db2051ff 213 Pfam PF00355 Rieske [2Fe-2S] domain 71 193 4.2E-12 T 14-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 LH59_00885 63115943bd771fa852c241e4db2051ff 213 PRINTS PR00162 Rieske 2Fe-2S subunit signature 165 177 9.9E-7 T 14-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 LH59_00885 63115943bd771fa852c241e4db2051ff 213 PRINTS PR00162 Rieske 2Fe-2S subunit signature 178 190 9.9E-7 T 14-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 LH59_00885 63115943bd771fa852c241e4db2051ff 213 PRINTS PR00162 Rieske 2Fe-2S subunit signature 133 144 9.9E-7 T 14-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 LH59_00885 63115943bd771fa852c241e4db2051ff 213 TIGRFAM TIGR01416 Rieske_proteo: ubiquinol-cytochrome c reductase, iron-sulfur subunit 24 206 1.1E-61 T 14-10-2018 IPR006317 Ubiquinol-cytochrome c reductase, iron-sulphur subunit GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 LH59_00885 63115943bd771fa852c241e4db2051ff 213 Gene3D G3DSA:2.102.10.10 56 206 1.7E-46 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 LH59_00885 63115943bd771fa852c241e4db2051ff 213 SUPERFAMILY SSF50022 44 211 4.58E-39 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 LH59_00055 cf3ed11f739d53d5e1985e122a3216dc 305 SUPERFAMILY SSF46785 1 85 5.17E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_00055 cf3ed11f739d53d5e1985e122a3216dc 305 SUPERFAMILY SSF53850 91 297 1.24E-36 T 14-10-2018 LH59_00055 cf3ed11f739d53d5e1985e122a3216dc 305 Gene3D G3DSA:1.10.10.10 1 82 6.6E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_00055 cf3ed11f739d53d5e1985e122a3216dc 305 Gene3D G3DSA:3.40.190.10 92 277 1.8E-37 T 14-10-2018 LH59_00055 cf3ed11f739d53d5e1985e122a3216dc 305 Pfam PF03466 LysR substrate binding domain 91 290 2.9E-38 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_00055 cf3ed11f739d53d5e1985e122a3216dc 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.1E-19 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_00055 cf3ed11f739d53d5e1985e122a3216dc 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.4E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_00055 cf3ed11f739d53d5e1985e122a3216dc 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.4E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_00055 cf3ed11f739d53d5e1985e122a3216dc 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.4E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_00055 cf3ed11f739d53d5e1985e122a3216dc 305 Gene3D G3DSA:3.40.190.10 164 266 1.8E-37 T 14-10-2018 LH59_06900 a32b9712e2dacc3902b5c4426cc9af89 592 Gene3D G3DSA:4.10.80.40 552 592 3.8E-12 T 14-10-2018 LH59_06900 a32b9712e2dacc3902b5c4426cc9af89 592 Gene3D G3DSA:1.20.58.100 436 551 1.4E-32 T 14-10-2018 LH59_06900 a32b9712e2dacc3902b5c4426cc9af89 592 Gene3D G3DSA:3.90.700.10 251 354 1.7E-163 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 LH59_06900 a32b9712e2dacc3902b5c4426cc9af89 592 SUPERFAMILY SSF51905 9 437 8.37E-79 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_06900 a32b9712e2dacc3902b5c4426cc9af89 592 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 14 591 7.9E-241 T 14-10-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 LH59_06900 a32b9712e2dacc3902b5c4426cc9af89 592 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 11 592 2.7E-280 T 14-10-2018 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 LH59_06900 a32b9712e2dacc3902b5c4426cc9af89 592 SUPERFAMILY SSF46977 456 592 5.36E-45 T 14-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 LH59_06900 a32b9712e2dacc3902b5c4426cc9af89 592 Pfam PF00890 FAD binding domain 14 408 6.0E-118 T 14-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 LH59_06900 a32b9712e2dacc3902b5c4426cc9af89 592 Pfam PF02910 Fumarate reductase flavoprotein C-term 470 591 2.3E-39 T 14-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 LH59_06900 a32b9712e2dacc3902b5c4426cc9af89 592 PIRSF PIRSF000171 4 582 8.6E-38 T 14-10-2018 LH59_06900 a32b9712e2dacc3902b5c4426cc9af89 592 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 48 57 - T 14-10-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 LH59_06900 a32b9712e2dacc3902b5c4426cc9af89 592 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 14 36 1.1E-5 T 14-10-2018 LH59_06900 a32b9712e2dacc3902b5c4426cc9af89 592 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 386 393 1.1E-5 T 14-10-2018 LH59_06900 a32b9712e2dacc3902b5c4426cc9af89 592 SUPERFAMILY SSF56425 241 359 8.97E-43 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 LH59_06900 a32b9712e2dacc3902b5c4426cc9af89 592 Gene3D G3DSA:3.50.50.60 14 419 1.7E-163 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_03515 33cc9c249726937bc0448758b830bd61 667 Gene3D G3DSA:3.30.450.20 67 221 1.1E-20 T 14-10-2018 LH59_03515 33cc9c249726937bc0448758b830bd61 667 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 476 666 7.1E-51 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 LH59_03515 33cc9c249726937bc0448758b830bd61 667 Gene3D G3DSA:1.20.1480.50 316 419 4.9E-7 T 14-10-2018 LH59_03515 33cc9c249726937bc0448758b830bd61 667 SMART SM00331 450 666 1.2E-54 T 14-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 LH59_03515 33cc9c249726937bc0448758b830bd61 667 Gene3D G3DSA:3.60.40.10 420 666 6.5E-71 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 LH59_03515 33cc9c249726937bc0448758b830bd61 667 SMART SM01049 67 160 2.4E-6 T 14-10-2018 IPR033480 Single Cache domain 2 LH59_03515 33cc9c249726937bc0448758b830bd61 667 SUPERFAMILY SSF81606 465 665 7.85E-8 T 14-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 LH59_03515 33cc9c249726937bc0448758b830bd61 667 Pfam PF08269 Cache domain 37 321 1.7E-22 T 14-10-2018 IPR004010 Double Cache domain 2 LH59_16450 ecb8221ff78ebb806232fc0c81dba13a 433 SUPERFAMILY SSF55205 1 429 1.41E-92 T 14-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 LH59_16450 ecb8221ff78ebb806232fc0c81dba13a 433 Gene3D G3DSA:3.65.10.10 6 427 3.8E-110 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 LH59_16450 ecb8221ff78ebb806232fc0c81dba13a 433 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 420 1.1E-53 T 14-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 LH59_16450 ecb8221ff78ebb806232fc0c81dba13a 433 Gene3D G3DSA:3.65.10.10 21 232 3.8E-110 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 LH59_10855 a392b37bea020950f59f5acb6f6bda1e 267 Gene3D G3DSA:3.40.50.150 54 226 4.7E-23 T 14-10-2018 LH59_10855 a392b37bea020950f59f5acb6f6bda1e 267 SUPERFAMILY SSF53335 55 190 6.39E-28 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_10855 a392b37bea020950f59f5acb6f6bda1e 267 Pfam PF08241 Methyltransferase domain 68 162 2.2E-16 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 LH59_07600 a3e84d81181795e092df5381ced541b7 335 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 11 188 6.7E-43 T 14-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain LH59_07600 a3e84d81181795e092df5381ced541b7 335 Gene3D G3DSA:3.40.50.300 6 205 1.1E-52 T 14-10-2018 LH59_07600 a3e84d81181795e092df5381ced541b7 335 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 237 326 1.1E-9 T 14-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal LH59_07600 a3e84d81181795e092df5381ced541b7 335 SUPERFAMILY SSF52540 7 186 1.51E-30 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_07600 a3e84d81181795e092df5381ced541b7 335 Gene3D G3DSA:3.30.1220.10 222 329 3.4E-11 T 14-10-2018 IPR036627 CobW-like, C-terminal domain superfamily LH59_07600 a3e84d81181795e092df5381ced541b7 335 SMART SM00833 236 330 3.5E-12 T 14-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal LH59_07600 a3e84d81181795e092df5381ced541b7 335 SUPERFAMILY SSF90002 236 325 1.06E-13 T 14-10-2018 LH59_19975 d190ae48d9c373bb64970683121b6c3f 369 SUPERFAMILY SSF51735 3 349 7.62E-85 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_19975 d190ae48d9c373bb64970683121b6c3f 369 Gene3D G3DSA:3.40.50.720 5 334 3.6E-165 T 14-10-2018 LH59_19975 d190ae48d9c373bb64970683121b6c3f 369 Gene3D G3DSA:3.90.25.10 193 348 3.6E-165 T 14-10-2018 LH59_19975 d190ae48d9c373bb64970683121b6c3f 369 Pfam PF16363 GDP-mannose 4,6 dehydratase 6 343 5.0E-158 T 14-10-2018 IPR016040 NAD(P)-binding domain LH59_19975 d190ae48d9c373bb64970683121b6c3f 369 Hamap MF_00955 GDP-mannose 4,6-dehydratase [gmd]. 3 353 56.999 T 14-10-2018 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 LH59_19975 d190ae48d9c373bb64970683121b6c3f 369 TIGRFAM TIGR01472 gmd: GDP-mannose 4,6-dehydratase 3 350 9.0E-176 T 14-10-2018 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 LH59_04945 62fb784c232937fff9a78c51b4f8a020 177 Gene3D G3DSA:3.40.50.850 1 177 7.3E-53 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 LH59_04945 62fb784c232937fff9a78c51b4f8a020 177 Pfam PF00857 Isochorismatase family 8 154 5.3E-28 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 LH59_04945 62fb784c232937fff9a78c51b4f8a020 177 SUPERFAMILY SSF52499 1 177 5.76E-45 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 LH59_18575 0e42528b9e09e7f5d2457ec91351d4d9 467 Gene3D G3DSA:1.20.1250.20 241 439 2.5E-18 T 14-10-2018 LH59_18575 0e42528b9e09e7f5d2457ec91351d4d9 467 Gene3D G3DSA:1.20.1250.20 10 220 7.3E-46 T 14-10-2018 LH59_18575 0e42528b9e09e7f5d2457ec91351d4d9 467 SUPERFAMILY SSF103473 11 445 2.22E-67 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_18575 0e42528b9e09e7f5d2457ec91351d4d9 467 Pfam PF07690 Major Facilitator Superfamily 25 390 3.2E-44 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_21165 aecbb06e3364ee9d5833781ee3b44220 334 Gene3D G3DSA:1.10.760.10 42 189 5.8E-117 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_21165 aecbb06e3364ee9d5833781ee3b44220 334 Gene3D G3DSA:1.10.760.10 40 312 5.8E-117 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_21165 aecbb06e3364ee9d5833781ee3b44220 334 PIRSF PIRSF000294 2 331 1.9E-133 T 14-10-2018 IPR026259 Di-c-type haem protein, MauG/cytochrome c peroxidase GO:0016491|GO:0020037|GO:0055114 LH59_21165 aecbb06e3364ee9d5833781ee3b44220 334 SUPERFAMILY SSF46626 27 177 2.36E-51 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_21165 aecbb06e3364ee9d5833781ee3b44220 334 Pfam PF03150 Di-haem cytochrome c peroxidase 42 189 3.4E-53 T 14-10-2018 IPR004852 Di-haem cytochrome c peroxidase GO:0016491|GO:0055114 LH59_21165 aecbb06e3364ee9d5833781ee3b44220 334 Pfam PF00034 Cytochrome c 198 307 8.1E-9 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_21165 aecbb06e3364ee9d5833781ee3b44220 334 SUPERFAMILY SSF46626 176 328 1.49E-42 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_27150 4351d97db6087519355b690c68a9dc64 227 Pfam PF06226 Protein of unknown function (DUF1007) 14 226 4.1E-54 T 14-10-2018 IPR010412 Protein of unknown function DUF1007 LH59_11225 e6069a7fda16863e73e2e702a3b85fb0 688 Gene3D G3DSA:1.10.1370.40 15 682 4.6E-235 T 14-10-2018 LH59_11225 e6069a7fda16863e73e2e702a3b85fb0 688 Gene3D G3DSA:1.10.1370.10 142 608 4.6E-235 T 14-10-2018 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 LH59_11225 e6069a7fda16863e73e2e702a3b85fb0 688 Pfam PF01432 Peptidase family M3 224 684 1.5E-125 T 14-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 LH59_11225 e6069a7fda16863e73e2e702a3b85fb0 688 SUPERFAMILY SSF55486 4 684 7.57E-174 T 14-10-2018 LH59_26430 ed0ca3d525dbecd4f91bf8e34080a76d 229 SUPERFAMILY SSF52172 1 126 3.42E-38 T 14-10-2018 IPR011006 CheY-like superfamily LH59_26430 ed0ca3d525dbecd4f91bf8e34080a76d 229 Gene3D G3DSA:1.10.10.60 167 224 6.2E-13 T 14-10-2018 LH59_26430 ed0ca3d525dbecd4f91bf8e34080a76d 229 SMART SM00448 2 114 8.3E-33 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_26430 ed0ca3d525dbecd4f91bf8e34080a76d 229 SUPERFAMILY SSF46689 161 221 1.33E-12 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_26430 ed0ca3d525dbecd4f91bf8e34080a76d 229 Pfam PF00072 Response regulator receiver domain 4 114 4.8E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_26430 ed0ca3d525dbecd4f91bf8e34080a76d 229 Gene3D G3DSA:3.40.50.2300 1 125 1.6E-34 T 14-10-2018 LH59_05910 38b5092d9c19ef80e18e9ae761b92a93 376 SMART SM00387 261 373 6.6E-25 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_05910 38b5092d9c19ef80e18e9ae761b92a93 376 SUPERFAMILY SSF47384 146 216 6.67E-13 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 LH59_05910 38b5092d9c19ef80e18e9ae761b92a93 376 SMART SM00388 151 217 2.2E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_05910 38b5092d9c19ef80e18e9ae761b92a93 376 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 262 371 6.4E-16 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_05910 38b5092d9c19ef80e18e9ae761b92a93 376 Pfam PF14361 RsbT co-antagonist protein rsbRD N-terminal domain 3 111 2.5E-9 T 14-10-2018 IPR025751 RsbT co-antagonist protein RsbRD, N-terminal domain LH59_05910 38b5092d9c19ef80e18e9ae761b92a93 376 Gene3D G3DSA:1.10.287.130 139 219 2.4E-11 T 14-10-2018 LH59_05910 38b5092d9c19ef80e18e9ae761b92a93 376 SUPERFAMILY SSF55874 225 373 6.42E-29 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_05910 38b5092d9c19ef80e18e9ae761b92a93 376 Pfam PF00512 His Kinase A (phospho-acceptor) domain 154 214 1.0E-7 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_05910 38b5092d9c19ef80e18e9ae761b92a93 376 Gene3D G3DSA:3.30.565.10 224 371 2.9E-28 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_19515 b6ee5d6c5a416d14cf63671a9511c03c 481 SUPERFAMILY SSF46894 412 480 1.63E-18 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LH59_19515 b6ee5d6c5a416d14cf63671a9511c03c 481 Gene3D G3DSA:1.10.3210.10 224 408 1.2E-31 T 14-10-2018 LH59_19515 b6ee5d6c5a416d14cf63671a9511c03c 481 Gene3D G3DSA:1.10.3210.10 9 204 8.8E-9 T 14-10-2018 LH59_19515 b6ee5d6c5a416d14cf63671a9511c03c 481 SUPERFAMILY SSF109604 246 402 6.85E-12 T 14-10-2018 LH59_19515 b6ee5d6c5a416d14cf63671a9511c03c 481 Pfam PF13487 HD domain 296 349 1.3E-10 T 14-10-2018 LH59_19515 b6ee5d6c5a416d14cf63671a9511c03c 481 Pfam PF00196 Bacterial regulatory proteins, luxR family 420 474 7.7E-16 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_19515 b6ee5d6c5a416d14cf63671a9511c03c 481 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 421 435 9.9E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_19515 b6ee5d6c5a416d14cf63671a9511c03c 481 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 451 463 9.9E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_19515 b6ee5d6c5a416d14cf63671a9511c03c 481 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 435 451 9.9E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_19515 b6ee5d6c5a416d14cf63671a9511c03c 481 Gene3D G3DSA:1.10.10.10 410 481 1.4E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_19515 b6ee5d6c5a416d14cf63671a9511c03c 481 SMART SM00421 418 475 2.9E-20 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_05195 3ee8713f53282f675c050ce7c6542e46 193 Gene3D G3DSA:2.20.70.10 14 50 2.2E-18 T 14-10-2018 LH59_05195 3ee8713f53282f675c050ce7c6542e46 193 Pfam PF00293 NUDIX domain 53 156 2.4E-12 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 LH59_05195 3ee8713f53282f675c050ce7c6542e46 193 SUPERFAMILY SSF55811 17 178 5.42E-39 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 LH59_05195 3ee8713f53282f675c050ce7c6542e46 193 ProSitePatterns PS00893 Nudix box signature. 85 106 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 LH59_05195 3ee8713f53282f675c050ce7c6542e46 193 Gene3D G3DSA:3.90.79.10 51 192 7.6E-36 T 14-10-2018 LH59_05195 3ee8713f53282f675c050ce7c6542e46 193 Pfam PF14803 Nudix N-terminal 17 50 5.8E-18 T 14-10-2018 IPR029401 Nudix hydrolase, N-terminal KEGG: 00230+3.6.1.13|KEGG: 00740+3.6.1.18 LH59_25850 eb07760144a027d9a73b186fdc2c1629 727 Gene3D G3DSA:3.40.50.970 397 589 4.7E-65 T 14-10-2018 LH59_25850 eb07760144a027d9a73b186fdc2c1629 727 SMART SM00861 399 575 4.0E-43 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain LH59_25850 eb07760144a027d9a73b186fdc2c1629 727 Pfam PF02780 Transketolase, C-terminal domain 591 712 2.4E-22 T 14-10-2018 IPR033248 Transketolase, C-terminal domain LH59_25850 eb07760144a027d9a73b186fdc2c1629 727 SUPERFAMILY SSF52922 585 720 6.28E-26 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 LH59_25850 eb07760144a027d9a73b186fdc2c1629 727 Gene3D G3DSA:3.40.50.920 590 721 3.0E-37 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 LH59_25850 eb07760144a027d9a73b186fdc2c1629 727 Gene3D G3DSA:3.40.50.970 8 364 3.7E-95 T 14-10-2018 LH59_25850 eb07760144a027d9a73b186fdc2c1629 727 SUPERFAMILY SSF52518 26 366 1.16E-73 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold LH59_25850 eb07760144a027d9a73b186fdc2c1629 727 Pfam PF02779 Transketolase, pyrimidine binding domain 402 573 4.4E-36 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain LH59_25850 eb07760144a027d9a73b186fdc2c1629 727 SUPERFAMILY SSF52518 401 600 4.43E-53 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold LH59_25850 eb07760144a027d9a73b186fdc2c1629 727 Pfam PF00676 Dehydrogenase E1 component 124 351 8.9E-52 T 14-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 LH59_16870 9dd9172b902875681cf47b87301f6ab7 323 SUPERFAMILY SSF52540 5 296 6.25E-41 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_16870 9dd9172b902875681cf47b87301f6ab7 323 PIRSF PIRSF002849 1 323 2.9E-122 T 14-10-2018 LH59_16870 9dd9172b902875681cf47b87301f6ab7 323 Gene3D G3DSA:1.10.8.300 204 319 1.5E-33 T 14-10-2018 LH59_16870 9dd9172b902875681cf47b87301f6ab7 323 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 37 170 2.2E-61 T 14-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 LH59_16870 9dd9172b902875681cf47b87301f6ab7 323 Gene3D G3DSA:3.40.50.300 18 186 1.4E-42 T 14-10-2018 LH59_26245 6a20e5258a85fa46585655d29fd0a8c1 128 SUPERFAMILY SSF46955 10 120 1.06E-24 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily LH59_26245 6a20e5258a85fa46585655d29fd0a8c1 128 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 11 22 2.1E-6 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LH59_26245 6a20e5258a85fa46585655d29fd0a8c1 128 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 22 35 2.1E-6 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LH59_26245 6a20e5258a85fa46585655d29fd0a8c1 128 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 45 65 2.1E-6 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LH59_26245 6a20e5258a85fa46585655d29fd0a8c1 128 SMART SM00422 10 78 6.6E-16 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LH59_26245 6a20e5258a85fa46585655d29fd0a8c1 128 Gene3D G3DSA:1.10.1660.10 3 127 9.8E-29 T 14-10-2018 LH59_26245 6a20e5258a85fa46585655d29fd0a8c1 128 Pfam PF13411 MerR HTH family regulatory protein 10 72 1.4E-13 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LH59_06950 a16b8b549da672dca0f4a0c653b00de4 564 SUPERFAMILY SSF158694 4 144 5.23E-17 T 14-10-2018 IPR036778 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase superfamily KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 LH59_06950 a16b8b549da672dca0f4a0c653b00de4 564 Gene3D G3DSA:3.30.70.360 363 476 1.6E-125 T 14-10-2018 LH59_06950 a16b8b549da672dca0f4a0c653b00de4 564 Gene3D G3DSA:1.10.3330.10 4 75 7.9E-9 T 14-10-2018 IPR036778 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase superfamily KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 LH59_06950 a16b8b549da672dca0f4a0c653b00de4 564 Gene3D G3DSA:1.10.3330.10 76 146 9.4E-7 T 14-10-2018 IPR036778 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase superfamily KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 LH59_06950 a16b8b549da672dca0f4a0c653b00de4 564 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 160 551 5.1E-102 T 14-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 LH59_06950 a16b8b549da672dca0f4a0c653b00de4 564 SUPERFAMILY SSF55031 363 476 3.49E-28 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain LH59_06950 a16b8b549da672dca0f4a0c653b00de4 564 Pfam PF07687 Peptidase dimerisation domain 362 459 1.3E-5 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain LH59_06950 a16b8b549da672dca0f4a0c653b00de4 564 SUPERFAMILY SSF53187 153 560 7.65E-75 T 14-10-2018 LH59_06950 a16b8b549da672dca0f4a0c653b00de4 564 Pfam PF01546 Peptidase family M20/M25/M40 229 556 1.9E-25 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 LH59_06950 a16b8b549da672dca0f4a0c653b00de4 564 Gene3D G3DSA:3.40.630.10 171 552 1.6E-125 T 14-10-2018 LH59_14815 1a76b89fa9c27f5ed1458f8475c8e076 806 SMART SM00965 73 123 4.2E-11 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 LH59_14815 1a76b89fa9c27f5ed1458f8475c8e076 806 Pfam PF07715 TonB-dependent Receptor Plug Domain 170 266 4.0E-15 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_14815 1a76b89fa9c27f5ed1458f8475c8e076 806 Gene3D G3DSA:2.40.170.20 284 806 1.6E-59 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_14815 1a76b89fa9c27f5ed1458f8475c8e076 806 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 172 806 2.7E-86 T 14-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 LH59_14815 1a76b89fa9c27f5ed1458f8475c8e076 806 Pfam PF07660 Secretin and TonB N terminus short domain 73 122 8.4E-7 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 LH59_14815 1a76b89fa9c27f5ed1458f8475c8e076 806 Pfam PF00593 TonB dependent receptor 391 801 7.4E-29 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_14815 1a76b89fa9c27f5ed1458f8475c8e076 806 Gene3D G3DSA:2.170.130.10 168 283 2.2E-20 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily LH59_14815 1a76b89fa9c27f5ed1458f8475c8e076 806 SUPERFAMILY SSF56935 125 806 1.05E-84 T 14-10-2018 LH59_14815 1a76b89fa9c27f5ed1458f8475c8e076 806 Gene3D G3DSA:3.55.50.30 51 121 1.1E-21 T 14-10-2018 LH59_26440 f65e286ebc7b238615db9b57503db4d8 196 Pfam PF14334 Domain of unknown function (DUF4390) 32 184 2.2E-50 T 14-10-2018 IPR025500 Protein of unknown function DUF4390 LH59_21975 11e326aa7dfa3d93288a30a6d5bc1757 302 SUPERFAMILY SSF46785 1 87 2.18E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_21975 11e326aa7dfa3d93288a30a6d5bc1757 302 SUPERFAMILY SSF53850 85 292 1.55E-19 T 14-10-2018 LH59_21975 11e326aa7dfa3d93288a30a6d5bc1757 302 Pfam PF03466 LysR substrate binding domain 88 288 2.0E-18 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_21975 11e326aa7dfa3d93288a30a6d5bc1757 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 7.0E-11 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_21975 11e326aa7dfa3d93288a30a6d5bc1757 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 7.0E-11 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_21975 11e326aa7dfa3d93288a30a6d5bc1757 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 7.0E-11 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_21975 11e326aa7dfa3d93288a30a6d5bc1757 302 Gene3D G3DSA:3.40.190.290 102 289 5.9E-18 T 14-10-2018 LH59_21975 11e326aa7dfa3d93288a30a6d5bc1757 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 1.6E-20 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_21975 11e326aa7dfa3d93288a30a6d5bc1757 302 Gene3D G3DSA:1.10.10.10 1 89 6.5E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_12220 866bf730e194636a20e1b3e65cadb974 875 Gene3D G3DSA:3.40.50.300 515 867 2.8E-12 T 14-10-2018 LH59_12220 866bf730e194636a20e1b3e65cadb974 875 Gene3D G3DSA:3.40.50.300 1 267 2.6E-21 T 14-10-2018 LH59_12220 866bf730e194636a20e1b3e65cadb974 875 SUPERFAMILY SSF52540 1 859 1.45E-16 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_12220 866bf730e194636a20e1b3e65cadb974 875 Pfam PF13514 AAA domain 1 47 7.4E-7 T 14-10-2018 IPR038734 Uncharacterized protein YhaN, AAA domain LH59_12115 50b98af4ce79f05e076ebc9f87b726d5 216 Gene3D G3DSA:2.160.10.10 1 211 4.8E-76 T 14-10-2018 LH59_12115 50b98af4ce79f05e076ebc9f87b726d5 216 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 110 144 1.8E-9 T 14-10-2018 IPR001451 Hexapeptide repeat LH59_12115 50b98af4ce79f05e076ebc9f87b726d5 216 SUPERFAMILY SSF51161 20 206 4.99E-46 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily LH59_12115 50b98af4ce79f05e076ebc9f87b726d5 216 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 119 147 - T 14-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 LH59_26155 32a7333ec71bcbf4c7746b34333b22cf 158 SMART SM00344 3 112 7.0E-32 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 LH59_26155 32a7333ec71bcbf4c7746b34333b22cf 158 SUPERFAMILY SSF54909 65 151 1.61E-17 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel LH59_26155 32a7333ec71bcbf4c7746b34333b22cf 158 Pfam PF13404 AsnC-type helix-turn-helix domain 3 44 6.3E-14 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_26155 32a7333ec71bcbf4c7746b34333b22cf 158 Pfam PF01037 Lrp/AsnC ligand binding domain 69 142 3.7E-19 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LH59_26155 32a7333ec71bcbf4c7746b34333b22cf 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 3.1E-11 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_26155 32a7333ec71bcbf4c7746b34333b22cf 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 3.1E-11 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_26155 32a7333ec71bcbf4c7746b34333b22cf 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 3.1E-11 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_26155 32a7333ec71bcbf4c7746b34333b22cf 158 SUPERFAMILY SSF46785 2 62 4.85E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_26155 32a7333ec71bcbf4c7746b34333b22cf 158 Gene3D G3DSA:3.30.70.920 56 139 6.0E-22 T 14-10-2018 LH59_26155 32a7333ec71bcbf4c7746b34333b22cf 158 Gene3D G3DSA:1.10.10.10 4 54 2.2E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_17810 c4dfedfc51728a49056fd53f2521dcf1 207 Pfam PF00043 Glutathione S-transferase, C-terminal domain 109 192 3.7E-11 T 14-10-2018 IPR004046 Glutathione S-transferase, C-terminal LH59_17810 c4dfedfc51728a49056fd53f2521dcf1 207 Gene3D G3DSA:1.20.1050.10 83 191 4.8E-70 T 14-10-2018 LH59_17810 c4dfedfc51728a49056fd53f2521dcf1 207 Gene3D G3DSA:3.40.30.10 2 201 4.8E-70 T 14-10-2018 LH59_17810 c4dfedfc51728a49056fd53f2521dcf1 207 SUPERFAMILY SSF47616 85 202 4.59E-32 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily LH59_17810 c4dfedfc51728a49056fd53f2521dcf1 207 SUPERFAMILY SSF52833 4 79 4.75E-23 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_17810 c4dfedfc51728a49056fd53f2521dcf1 207 Pfam PF02798 Glutathione S-transferase, N-terminal domain 9 75 7.0E-16 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 LH59_04125 94d10d5c410a7e9271e1db2b3fed8fbc 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 1.1E-11 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_04125 94d10d5c410a7e9271e1db2b3fed8fbc 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 1.1E-11 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_04125 94d10d5c410a7e9271e1db2b3fed8fbc 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 1.1E-11 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_04125 94d10d5c410a7e9271e1db2b3fed8fbc 152 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 14-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site LH59_04125 94d10d5c410a7e9271e1db2b3fed8fbc 152 Pfam PF01037 Lrp/AsnC ligand binding domain 67 139 9.9E-19 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LH59_04125 94d10d5c410a7e9271e1db2b3fed8fbc 152 SUPERFAMILY SSF46785 1 81 7.91E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_04125 94d10d5c410a7e9271e1db2b3fed8fbc 152 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 47 7.6E-20 T 14-10-2018 LH59_04125 94d10d5c410a7e9271e1db2b3fed8fbc 152 SMART SM00344 1 110 4.4E-42 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 LH59_04125 94d10d5c410a7e9271e1db2b3fed8fbc 152 Gene3D G3DSA:3.30.70.920 54 137 1.2E-24 T 14-10-2018 LH59_04125 94d10d5c410a7e9271e1db2b3fed8fbc 152 Gene3D G3DSA:1.10.10.10 1 53 3.5E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_04125 94d10d5c410a7e9271e1db2b3fed8fbc 152 SUPERFAMILY SSF54909 61 149 1.29E-19 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel LH59_03300 937643a8b26be3675576c62221fd7552 230 Pfam PF00857 Isochorismatase family 29 214 6.2E-37 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 LH59_03300 937643a8b26be3675576c62221fd7552 230 SUPERFAMILY SSF52499 24 220 1.57E-52 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 LH59_03300 937643a8b26be3675576c62221fd7552 230 Gene3D G3DSA:3.40.50.850 7 230 1.6E-57 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 LH59_21805 896ef27228399a48c491690cbf6e50ea 207 Pfam PF00857 Isochorismatase family 14 165 1.4E-22 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 LH59_21805 896ef27228399a48c491690cbf6e50ea 207 SUPERFAMILY SSF52499 4 201 1.83E-53 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 LH59_21805 896ef27228399a48c491690cbf6e50ea 207 Gene3D G3DSA:3.40.50.850 1 207 6.6E-59 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 LH59_10640 53e194c8b02f17f3d3b61a11b4506b85 719 Gene3D G3DSA:2.40.170.20 190 719 7.2E-159 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_10640 53e194c8b02f17f3d3b61a11b4506b85 719 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 86 716 1.1E-105 T 14-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 LH59_10640 53e194c8b02f17f3d3b61a11b4506b85 719 SUPERFAMILY SSF56935 39 719 6.18E-126 T 14-10-2018 LH59_10640 53e194c8b02f17f3d3b61a11b4506b85 719 Pfam PF07715 TonB-dependent Receptor Plug Domain 84 182 4.4E-17 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_10640 53e194c8b02f17f3d3b61a11b4506b85 719 Gene3D G3DSA:2.170.130.10 62 189 5.1E-35 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily LH59_10640 53e194c8b02f17f3d3b61a11b4506b85 719 Pfam PF00593 TonB dependent receptor 290 717 4.0E-55 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_23700 ca412008341e55a62ace09ce4da70c7f 338 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 35 252 4.5E-27 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_23700 ca412008341e55a62ace09ce4da70c7f 338 Gene3D G3DSA:3.40.190.10 29 244 8.1E-47 T 14-10-2018 LH59_23700 ca412008341e55a62ace09ce4da70c7f 338 SMART SM00062 34 263 7.4E-36 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_23700 ca412008341e55a62ace09ce4da70c7f 338 Gene3D G3DSA:3.40.190.10 121 226 8.1E-47 T 14-10-2018 LH59_23700 ca412008341e55a62ace09ce4da70c7f 338 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 57 70 - T 14-10-2018 IPR018313 Solute-binding protein family 3, conserved site LH59_23700 ca412008341e55a62ace09ce4da70c7f 338 SUPERFAMILY SSF53850 25 254 4.26E-44 T 14-10-2018 LH59_25855 569789ef21233d1d9daf530001f451e1 163 SUPERFAMILY SSF54593 13 151 6.58E-23 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_25855 569789ef21233d1d9daf530001f451e1 163 Gene3D G3DSA:3.10.180.10 9 149 4.0E-23 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_25855 569789ef21233d1d9daf530001f451e1 163 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 13 145 3.2E-10 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain LH59_27460 017786361f705bb5f7c6090e876da736 452 SUPERFAMILY SSF103473 6 443 9.81E-65 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_27460 017786361f705bb5f7c6090e876da736 452 Gene3D G3DSA:1.20.1250.20 252 448 1.6E-25 T 14-10-2018 LH59_27460 017786361f705bb5f7c6090e876da736 452 Gene3D G3DSA:1.20.1720.10 4 215 5.5E-46 T 14-10-2018 LH59_27460 017786361f705bb5f7c6090e876da736 452 Pfam PF07690 Major Facilitator Superfamily 7 402 5.1E-54 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_27460 017786361f705bb5f7c6090e876da736 452 PRINTS PR01036 Tetracycline resistance protein TetB signature 64 86 4.6E-6 T 14-10-2018 LH59_27460 017786361f705bb5f7c6090e876da736 452 PRINTS PR01036 Tetracycline resistance protein TetB signature 393 412 4.6E-6 T 14-10-2018 LH59_27460 017786361f705bb5f7c6090e876da736 452 PRINTS PR01036 Tetracycline resistance protein TetB signature 126 150 4.6E-6 T 14-10-2018 LH59_06310 32ed37da6b3a1825c6c25ac94fa77c82 254 SUPERFAMILY SSF52540 6 243 1.85E-53 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_06310 32ed37da6b3a1825c6c25ac94fa77c82 254 Pfam PF00005 ABC transporter 25 173 1.4E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_06310 32ed37da6b3a1825c6c25ac94fa77c82 254 SMART SM00382 32 218 7.4E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_06310 32ed37da6b3a1825c6c25ac94fa77c82 254 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_06310 32ed37da6b3a1825c6c25ac94fa77c82 254 Gene3D G3DSA:3.40.50.300 3 246 1.2E-56 T 14-10-2018 LH59_27600 2a48cf9be74ee5b24e7d3c7d395bd705 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 5.1E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_27600 2a48cf9be74ee5b24e7d3c7d395bd705 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 5.1E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_27600 2a48cf9be74ee5b24e7d3c7d395bd705 196 Gene3D G3DSA:1.10.357.10 3 188 2.6E-50 T 14-10-2018 LH59_27600 2a48cf9be74ee5b24e7d3c7d395bd705 196 SUPERFAMILY SSF48498 79 186 4.13E-19 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily LH59_27600 2a48cf9be74ee5b24e7d3c7d395bd705 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 58 1.1E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_27600 2a48cf9be74ee5b24e7d3c7d395bd705 196 SUPERFAMILY SSF46689 5 76 3.08E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_22310 42d3e4706b44cdadaa7437570bf89a2d 262 Pfam PF09339 IclR helix-turn-helix domain 19 70 2.8E-12 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_22310 42d3e4706b44cdadaa7437570bf89a2d 262 SUPERFAMILY SSF46785 19 88 6.45E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_22310 42d3e4706b44cdadaa7437570bf89a2d 262 SUPERFAMILY SSF55781 82 260 3.2E-50 T 14-10-2018 LH59_22310 42d3e4706b44cdadaa7437570bf89a2d 262 SMART SM00346 17 105 1.6E-19 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_22310 42d3e4706b44cdadaa7437570bf89a2d 262 Gene3D G3DSA:3.30.450.40 86 262 5.3E-57 T 14-10-2018 IPR029016 GAF-like domain superfamily LH59_22310 42d3e4706b44cdadaa7437570bf89a2d 262 Pfam PF01614 Bacterial transcriptional regulator 137 256 5.8E-33 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal LH59_22310 42d3e4706b44cdadaa7437570bf89a2d 262 Gene3D G3DSA:1.10.10.10 11 85 2.2E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_10610 b8b9d581e57b5cf2f6750a1ce63878e9 383 SUPERFAMILY SSF89796 9 377 2.75E-118 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily LH59_10610 b8b9d581e57b5cf2f6750a1ce63878e9 383 Gene3D G3DSA:3.40.50.10540 10 376 6.5E-112 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily LH59_10610 b8b9d581e57b5cf2f6750a1ce63878e9 383 Pfam PF02515 CoA-transferase family III 11 376 1.7E-113 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 LH59_10610 b8b9d581e57b5cf2f6750a1ce63878e9 383 Gene3D G3DSA:3.30.1540.10 236 328 6.5E-112 T 14-10-2018 LH59_13485 7229971a382b62ff4837e07b574cc5f8 517 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 358 513 1.0E-42 T 14-10-2018 IPR000160 GGDEF domain LH59_13485 7229971a382b62ff4837e07b574cc5f8 517 Gene3D G3DSA:3.30.70.270 355 515 1.8E-52 T 14-10-2018 LH59_13485 7229971a382b62ff4837e07b574cc5f8 517 SUPERFAMILY SSF55073 365 514 7.85E-46 T 14-10-2018 IPR029787 Nucleotide cyclase LH59_13485 7229971a382b62ff4837e07b574cc5f8 517 SUPERFAMILY SSF103190 186 261 2.35E-15 T 14-10-2018 IPR029151 Periplasmic sensor-like domain superfamily LH59_13485 7229971a382b62ff4837e07b574cc5f8 517 Pfam PF02743 Cache domain 35 262 5.9E-25 T 14-10-2018 IPR033479 Double Cache domain 1 LH59_13485 7229971a382b62ff4837e07b574cc5f8 517 Gene3D G3DSA:3.30.450.20 31 174 3.3E-14 T 14-10-2018 LH59_13485 7229971a382b62ff4837e07b574cc5f8 517 SMART SM00267 349 514 1.8E-55 T 14-10-2018 IPR000160 GGDEF domain LH59_13485 7229971a382b62ff4837e07b574cc5f8 517 Pfam PF00990 Diguanylate cyclase, GGDEF domain 361 510 1.8E-41 T 14-10-2018 IPR000160 GGDEF domain LH59_13485 7229971a382b62ff4837e07b574cc5f8 517 SUPERFAMILY SSF103190 78 171 5.89E-8 T 14-10-2018 IPR029151 Periplasmic sensor-like domain superfamily LH59_16710 b605b6d89eafe47b049b9eb27673e1c9 291 SUPERFAMILY SSF46785 3 84 5.88E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_16710 b605b6d89eafe47b049b9eb27673e1c9 291 SUPERFAMILY SSF53850 92 287 4.07E-31 T 14-10-2018 LH59_16710 b605b6d89eafe47b049b9eb27673e1c9 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 6.3E-20 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_16710 b605b6d89eafe47b049b9eb27673e1c9 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 1.1E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_16710 b605b6d89eafe47b049b9eb27673e1c9 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 1.1E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_16710 b605b6d89eafe47b049b9eb27673e1c9 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 1.1E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_16710 b605b6d89eafe47b049b9eb27673e1c9 291 Gene3D G3DSA:3.40.190.10 102 282 8.2E-43 T 14-10-2018 LH59_16710 b605b6d89eafe47b049b9eb27673e1c9 291 Pfam PF03466 LysR substrate binding domain 91 271 4.3E-31 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_16710 b605b6d89eafe47b049b9eb27673e1c9 291 Gene3D G3DSA:3.40.190.10 162 258 8.2E-43 T 14-10-2018 LH59_16710 b605b6d89eafe47b049b9eb27673e1c9 291 Gene3D G3DSA:1.10.10.10 6 91 4.1E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_09565 bfe2a9f41378168446f8cbbfeee9e47f 499 SUPERFAMILY SSF53720 8 497 1.96E-164 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 LH59_09565 bfe2a9f41378168446f8cbbfeee9e47f 499 Gene3D G3DSA:3.40.605.10 34 492 1.7E-174 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 LH59_09565 bfe2a9f41378168446f8cbbfeee9e47f 499 Gene3D G3DSA:3.40.309.10 270 462 1.7E-174 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 LH59_09565 bfe2a9f41378168446f8cbbfeee9e47f 499 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 295 306 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 LH59_09565 bfe2a9f41378168446f8cbbfeee9e47f 499 Pfam PF00171 Aldehyde dehydrogenase family 32 492 6.9E-168 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 LH59_09565 bfe2a9f41378168446f8cbbfeee9e47f 499 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 266 273 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 LH59_18285 567e8330552af48aa692bca7d0c47190 181 SUPERFAMILY SSF52499 2 168 1.7E-44 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 LH59_18285 567e8330552af48aa692bca7d0c47190 181 Pfam PF00857 Isochorismatase family 3 150 2.6E-35 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 LH59_18285 567e8330552af48aa692bca7d0c47190 181 Gene3D G3DSA:3.40.50.850 1 175 7.1E-44 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 LH59_23195 37c0ddf794bd934165429230336c1e94 333 Gene3D G3DSA:2.60.120.1440 115 245 3.1E-12 T 14-10-2018 LH59_23195 37c0ddf794bd934165429230336c1e94 333 Pfam PF04773 FecR protein 123 217 4.7E-15 T 14-10-2018 IPR006860 FecR protein LH59_23195 37c0ddf794bd934165429230336c1e94 333 PIRSF PIRSF018266 16 329 1.6E-82 T 14-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component LH59_23195 37c0ddf794bd934165429230336c1e94 333 Pfam PF16220 Domain of unknown function (DUF4880) 26 68 2.0E-10 T 14-10-2018 IPR032623 FecR, N-terminal LH59_08925 e153d7bf2fea73e5795ce0883fb203ff 329 SUPERFAMILY SSF51735 115 271 2.33E-45 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_08925 e153d7bf2fea73e5795ce0883fb203ff 329 Pfam PF00107 Zinc-binding dehydrogenase 155 262 5.8E-27 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 LH59_08925 e153d7bf2fea73e5795ce0883fb203ff 329 Gene3D G3DSA:3.40.50.720 127 272 8.6E-116 T 14-10-2018 LH59_08925 e153d7bf2fea73e5795ce0883fb203ff 329 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 144 165 - T 14-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 LH59_08925 e153d7bf2fea73e5795ce0883fb203ff 329 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 33 90 6.9E-9 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 LH59_08925 e153d7bf2fea73e5795ce0883fb203ff 329 SUPERFAMILY SSF50129 6 148 1.89E-38 T 14-10-2018 IPR011032 GroES-like superfamily LH59_08925 e153d7bf2fea73e5795ce0883fb203ff 329 SMART SM00829 15 326 6.2E-36 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 LH59_08925 e153d7bf2fea73e5795ce0883fb203ff 329 Gene3D G3DSA:3.90.180.10 16 322 8.6E-116 T 14-10-2018 LH59_12370 125cb744b425031b01b0ee4eea316a27 259 Pfam PF10108 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB 47 256 2.0E-90 T 14-10-2018 IPR019288 Predicted 3'-5' exonuclease, PolB-like LH59_12370 125cb744b425031b01b0ee4eea316a27 259 SUPERFAMILY SSF53098 4 228 8.13E-40 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily LH59_12370 125cb744b425031b01b0ee4eea316a27 259 Gene3D G3DSA:3.30.420.10 5 214 2.1E-17 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 LH59_21110 057287250843bd65eda2c639c061f082 53 Pfam PF03597 Cytochrome oxidase maturation protein cbb3-type 3 45 1.8E-17 T 14-10-2018 IPR004714 Cytochrome oxidase maturation protein cbb3-type LH59_21110 057287250843bd65eda2c639c061f082 53 TIGRFAM TIGR00847 ccoS: cytochrome oxidase maturation protein, cbb3-type 1 46 4.2E-13 T 14-10-2018 IPR004714 Cytochrome oxidase maturation protein cbb3-type LH59_19050 89bd8ad0c37d0951d149dc534ba2b926 271 SUPERFAMILY SSF55781 97 262 1.96E-22 T 14-10-2018 LH59_19050 89bd8ad0c37d0951d149dc534ba2b926 271 Pfam PF09339 IclR helix-turn-helix domain 25 75 1.3E-15 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_19050 89bd8ad0c37d0951d149dc534ba2b926 271 SUPERFAMILY SSF46785 25 95 6.34E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_19050 89bd8ad0c37d0951d149dc534ba2b926 271 Gene3D G3DSA:3.30.450.40 96 262 2.7E-20 T 14-10-2018 IPR029016 GAF-like domain superfamily LH59_19050 89bd8ad0c37d0951d149dc534ba2b926 271 SMART SM00346 23 113 3.7E-15 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_19050 89bd8ad0c37d0951d149dc534ba2b926 271 Gene3D G3DSA:1.10.10.10 16 91 4.1E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_19050 89bd8ad0c37d0951d149dc534ba2b926 271 Pfam PF01614 Bacterial transcriptional regulator 147 239 7.4E-5 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal LH59_03735 c225f0660780d21df06c75551ade5522 308 Pfam PF00892 EamA-like transporter family 24 142 1.8E-12 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_03735 c225f0660780d21df06c75551ade5522 308 Pfam PF00892 EamA-like transporter family 165 296 2.2E-12 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_03735 c225f0660780d21df06c75551ade5522 308 SUPERFAMILY SSF103481 66 153 2.09E-9 T 14-10-2018 LH59_03735 c225f0660780d21df06c75551ade5522 308 SUPERFAMILY SSF103481 199 296 2.09E-7 T 14-10-2018 LH59_03265 1c722c81b8e0bcf971595b29bc6f4548 300 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 235 1.4E-41 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_03265 1c722c81b8e0bcf971595b29bc6f4548 300 Gene3D G3DSA:3.40.190.150 33 130 2.3E-63 T 14-10-2018 LH59_03265 1c722c81b8e0bcf971595b29bc6f4548 300 Gene3D G3DSA:3.40.190.150 236 290 7.1E-9 T 14-10-2018 LH59_03265 1c722c81b8e0bcf971595b29bc6f4548 300 SUPERFAMILY SSF53850 116 258 2.35E-6 T 14-10-2018 LH59_03265 1c722c81b8e0bcf971595b29bc6f4548 300 PIRSF PIRSF017082 1 237 6.9E-49 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_03265 1c722c81b8e0bcf971595b29bc6f4548 300 PIRSF PIRSF017082 233 300 2.7E-6 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_03265 1c722c81b8e0bcf971595b29bc6f4548 300 Gene3D G3DSA:3.40.190.10 131 235 2.3E-63 T 14-10-2018 LH59_26310 17499df26782be78c6b4f0fa313d9f9e 378 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 3 335 7.0E-137 T 14-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 LH59_26310 17499df26782be78c6b4f0fa313d9f9e 378 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 211 226 5.1E-34 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 LH59_26310 17499df26782be78c6b4f0fa313d9f9e 378 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 228 246 5.1E-34 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 LH59_26310 17499df26782be78c6b4f0fa313d9f9e 378 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 5.1E-34 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 LH59_26310 17499df26782be78c6b4f0fa313d9f9e 378 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 5.1E-34 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 LH59_26310 17499df26782be78c6b4f0fa313d9f9e 378 Gene3D G3DSA:2.70.210.12 1 158 4.7E-58 T 14-10-2018 IPR036726 GTP1/OBG domain superfamily LH59_26310 17499df26782be78c6b4f0fa313d9f9e 378 ProSitePatterns PS00905 GTP1/OBG family signature. 213 226 - T 14-10-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 LH59_26310 17499df26782be78c6b4f0fa313d9f9e 378 PIRSF PIRSF002401 1 373 9.6E-133 T 14-10-2018 IPR035101 GTP-binding protein, Obg-type LH59_26310 17499df26782be78c6b4f0fa313d9f9e 378 Pfam PF01018 GTP1/OBG 4 158 1.8E-58 T 14-10-2018 IPR006169 GTP1/OBG domain LH59_26310 17499df26782be78c6b4f0fa313d9f9e 378 Gene3D G3DSA:3.40.50.300 159 349 4.2E-49 T 14-10-2018 LH59_26310 17499df26782be78c6b4f0fa313d9f9e 378 Hamap MF_01454 GTPase Obg [obg]. 2 336 46.878 T 14-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 LH59_26310 17499df26782be78c6b4f0fa313d9f9e 378 Pfam PF01926 50S ribosome-binding GTPase 161 289 7.4E-24 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 LH59_26310 17499df26782be78c6b4f0fa313d9f9e 378 SUPERFAMILY SSF52540 151 343 7.88E-48 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_26310 17499df26782be78c6b4f0fa313d9f9e 378 SUPERFAMILY SSF82051 2 158 6.41E-56 T 14-10-2018 IPR036726 GTP1/OBG domain superfamily LH59_13610 e8deb4147ed55b4e875771db9d6f26c0 484 Pfam PF07969 Amidohydrolase family 318 464 4.2E-16 T 14-10-2018 IPR013108 Amidohydrolase 3 LH59_13610 e8deb4147ed55b4e875771db9d6f26c0 484 Pfam PF07969 Amidohydrolase family 53 252 3.5E-18 T 14-10-2018 IPR013108 Amidohydrolase 3 LH59_13610 e8deb4147ed55b4e875771db9d6f26c0 484 Gene3D G3DSA:3.30.1490.130 289 345 1.8E-252 T 14-10-2018 IPR023100 D-aminoacylase, insert domain superfamily GO:0016811 LH59_13610 e8deb4147ed55b4e875771db9d6f26c0 484 Gene3D G3DSA:2.30.40.10 8 464 1.8E-252 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 LH59_13610 e8deb4147ed55b4e875771db9d6f26c0 484 SUPERFAMILY SSF51556 63 420 1.26E-90 T 14-10-2018 IPR032466 Metal-dependent hydrolase LH59_13610 e8deb4147ed55b4e875771db9d6f26c0 484 SUPERFAMILY SSF51338 9 477 5.73E-19 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 LH59_13610 e8deb4147ed55b4e875771db9d6f26c0 484 Gene3D G3DSA:3.20.20.140 62 415 1.8E-252 T 14-10-2018 LH59_04520 a4d56000f0102935950e4af21ee620c8 370 Gene3D G3DSA:1.20.140.10 236 370 3.2E-30 T 14-10-2018 LH59_04520 a4d56000f0102935950e4af21ee620c8 370 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 364 7.5E-24 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LH59_04520 a4d56000f0102935950e4af21ee620c8 370 Gene3D G3DSA:1.10.540.10 1 118 3.5E-25 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 LH59_04520 a4d56000f0102935950e4af21ee620c8 370 SUPERFAMILY SSF56645 1 216 1.24E-40 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 LH59_04520 a4d56000f0102935950e4af21ee620c8 370 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 116 7.7E-16 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 LH59_04520 a4d56000f0102935950e4af21ee620c8 370 SUPERFAMILY SSF47203 226 366 1.35E-32 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 LH59_04520 a4d56000f0102935950e4af21ee620c8 370 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 136 207 2.6E-8 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 LH59_04520 a4d56000f0102935950e4af21ee620c8 370 Gene3D G3DSA:2.40.110.10 128 235 4.3E-15 T 14-10-2018 LH59_07490 92b5424762448038b80b55fa91241d71 254 PIRSF PIRSF037834 1 254 2.0E-100 T 14-10-2018 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 LH59_07490 92b5424762448038b80b55fa91241d71 254 Gene3D G3DSA:1.20.1260.10 1 254 3.4E-101 T 14-10-2018 IPR012347 Ferritin-like LH59_07490 92b5424762448038b80b55fa91241d71 254 Pfam PF05138 Phenylacetic acid catabolic protein 3 254 9.4E-97 T 14-10-2018 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 LH59_07490 92b5424762448038b80b55fa91241d71 254 SUPERFAMILY SSF47240 3 248 2.51E-81 T 14-10-2018 IPR009078 Ferritin-like superfamily LH59_07490 92b5424762448038b80b55fa91241d71 254 TIGRFAM TIGR02158 PA_CoA_Oxy3: phenylacetate-CoA oxygenase, PaaI subunit 12 254 2.3E-86 T 14-10-2018 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 LH59_09670 558236c5b0aed14d8be5e08576dc15ed 65 Gene3D G3DSA:2.40.50.530 1 65 1.3E-21 T 14-10-2018 LH59_09670 558236c5b0aed14d8be5e08576dc15ed 65 PRINTS PR00064 Ribosomal protein L35 signature 21 35 1.7E-18 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 LH59_09670 558236c5b0aed14d8be5e08576dc15ed 65 PRINTS PR00064 Ribosomal protein L35 signature 36 54 1.7E-18 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 LH59_09670 558236c5b0aed14d8be5e08576dc15ed 65 PRINTS PR00064 Ribosomal protein L35 signature 3 20 1.7E-18 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 LH59_09670 558236c5b0aed14d8be5e08576dc15ed 65 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 18.774 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 LH59_09670 558236c5b0aed14d8be5e08576dc15ed 65 Pfam PF01632 Ribosomal protein L35 2 62 1.3E-25 T 14-10-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_09670 558236c5b0aed14d8be5e08576dc15ed 65 SUPERFAMILY SSF143034 2 64 1.23E-23 T 14-10-2018 IPR037229 Ribosomal protein L35 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_09670 558236c5b0aed14d8be5e08576dc15ed 65 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 63 3.6E-27 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 LH59_09670 558236c5b0aed14d8be5e08576dc15ed 65 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 14-10-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_24800 ce8d367c008715401e6d4f6ca81e4392 491 PIRSF PIRSF012702 1 491 1.4E-166 T 14-10-2018 IPR009197 Microcystin LR degradation protein MlrC LH59_24800 ce8d367c008715401e6d4f6ca81e4392 491 Pfam PF07171 MlrC C-terminus 299 480 5.1E-52 T 14-10-2018 IPR010799 Microcystin LR degradation protein MlrC, C-terminal LH59_24800 ce8d367c008715401e6d4f6ca81e4392 491 Pfam PF07364 Metallopeptidase family M81 2 289 7.8E-87 T 14-10-2018 IPR015995 Microcystin LR degradation protein MlrC, N-terminal LH59_24190 18d55d06d348209b3ec5a1db66a69887 195 Gene3D G3DSA:1.10.357.10 6 193 1.6E-59 T 14-10-2018 LH59_24190 18d55d06d348209b3ec5a1db66a69887 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 58 5.6E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_24190 18d55d06d348209b3ec5a1db66a69887 195 SUPERFAMILY SSF46689 11 83 5.49E-12 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_24190 18d55d06d348209b3ec5a1db66a69887 195 SUPERFAMILY SSF48498 78 191 1.48E-27 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily LH59_01220 9794b59ffeb458a64e9b3ddb72f3eb86 610 Pfam PF01380 SIS domain 464 590 1.0E-25 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 LH59_01220 9794b59ffeb458a64e9b3ddb72f3eb86 610 Pfam PF01380 SIS domain 292 417 9.5E-27 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 LH59_01220 9794b59ffeb458a64e9b3ddb72f3eb86 610 SUPERFAMILY SSF53697 248 610 3.53E-109 T 14-10-2018 LH59_01220 9794b59ffeb458a64e9b3ddb72f3eb86 610 Gene3D G3DSA:3.40.50.10490 448 595 2.5E-139 T 14-10-2018 LH59_01220 9794b59ffeb458a64e9b3ddb72f3eb86 610 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 610 1.0E-250 T 14-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 LH59_01220 9794b59ffeb458a64e9b3ddb72f3eb86 610 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 610 39.166 T 14-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 LH59_01220 9794b59ffeb458a64e9b3ddb72f3eb86 610 Pfam PF13522 Glutamine amidotransferase domain 56 195 3.6E-22 T 14-10-2018 LH59_01220 9794b59ffeb458a64e9b3ddb72f3eb86 610 Gene3D G3DSA:3.60.20.10 2 244 6.9E-76 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal LH59_01220 9794b59ffeb458a64e9b3ddb72f3eb86 610 Gene3D G3DSA:3.40.50.10490 252 609 2.5E-139 T 14-10-2018 LH59_01220 9794b59ffeb458a64e9b3ddb72f3eb86 610 SUPERFAMILY SSF56235 2 239 6.6E-73 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal LH59_26740 63000c9cd5721900ed670bbf9d675497 378 Hamap MF_02079 Peptidoglycan glycosyltransferase MrdB [mrdB]. 10 377 28.195 T 14-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 LH59_26740 63000c9cd5721900ed670bbf9d675497 378 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 332 356 - T 14-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 LH59_26740 63000c9cd5721900ed670bbf9d675497 378 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 16 374 4.4E-129 T 14-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 LH59_26740 63000c9cd5721900ed670bbf9d675497 378 Pfam PF01098 Cell cycle protein 20 374 5.4E-101 T 14-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 LH59_07665 67f331138478a29bb2b90a0d65e1acbb 314 Pfam PF03466 LysR substrate binding domain 102 299 4.9E-26 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_07665 67f331138478a29bb2b90a0d65e1acbb 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 18 77 6.2E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_07665 67f331138478a29bb2b90a0d65e1acbb 314 SUPERFAMILY SSF53850 103 308 6.52E-28 T 14-10-2018 LH59_07665 67f331138478a29bb2b90a0d65e1acbb 314 Gene3D G3DSA:3.40.190.10 180 285 1.4E-26 T 14-10-2018 LH59_07665 67f331138478a29bb2b90a0d65e1acbb 314 SUPERFAMILY SSF46785 17 125 3.48E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_07665 67f331138478a29bb2b90a0d65e1acbb 314 Gene3D G3DSA:1.10.10.10 16 103 8.6E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_07665 67f331138478a29bb2b90a0d65e1acbb 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 54 8.1E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_07665 67f331138478a29bb2b90a0d65e1acbb 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 54 65 8.1E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_07665 67f331138478a29bb2b90a0d65e1acbb 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 44 8.1E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_07665 67f331138478a29bb2b90a0d65e1acbb 314 Gene3D G3DSA:3.40.190.10 108 291 1.4E-26 T 14-10-2018 LH59_13320 f022bb0d206458307abeba702c316f99 401 Gene3D G3DSA:1.20.1720.10 14 393 4.6E-82 T 14-10-2018 LH59_13320 f022bb0d206458307abeba702c316f99 401 SUPERFAMILY SSF103473 8 394 8.5E-49 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_13320 f022bb0d206458307abeba702c316f99 401 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 14 364 8.6E-68 T 14-10-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0006855|GO:0015238|GO:0016021 LH59_13320 f022bb0d206458307abeba702c316f99 401 Pfam PF07690 Major Facilitator Superfamily 21 360 6.9E-37 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_13320 f022bb0d206458307abeba702c316f99 401 ProSitePatterns PS00216 Sugar transport proteins signature 1. 68 85 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 LH59_05665 6f6e66beb04f24d606458190ee8838c4 89 Pfam PF00312 Ribosomal protein S15 8 88 9.0E-38 T 14-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_05665 6f6e66beb04f24d606458190ee8838c4 89 Gene3D G3DSA:1.10.287.10 1 89 5.6E-36 T 14-10-2018 LH59_05665 6f6e66beb04f24d606458190ee8838c4 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 88 1.0E-31 T 14-10-2018 LH59_05665 6f6e66beb04f24d606458190ee8838c4 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 22.037 T 14-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_05665 6f6e66beb04f24d606458190ee8838c4 89 SMART SM01387 8 88 1.2E-52 T 14-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_05665 6f6e66beb04f24d606458190ee8838c4 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 14-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_05665 6f6e66beb04f24d606458190ee8838c4 89 SUPERFAMILY SSF47060 4 89 2.94E-35 T 14-10-2018 IPR009068 S15/NS1, RNA-binding LH59_05665 6f6e66beb04f24d606458190ee8838c4 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 6 89 9.0E-39 T 14-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_04865 e904199df00599239e4ca8586af29187 437 SUPERFAMILY SSF55961 162 436 2.2E-56 T 14-10-2018 LH59_04865 e904199df00599239e4ca8586af29187 437 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 78 98 4.1E-34 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 LH59_04865 e904199df00599239e4ca8586af29187 437 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 146 172 4.1E-34 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 LH59_04865 e904199df00599239e4ca8586af29187 437 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 57 72 4.1E-34 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 LH59_04865 e904199df00599239e4ca8586af29187 437 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 188 210 4.1E-34 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 LH59_04865 e904199df00599239e4ca8586af29187 437 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 27 52 4.1E-34 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 LH59_04865 e904199df00599239e4ca8586af29187 437 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 100 120 4.1E-34 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 LH59_04865 e904199df00599239e4ca8586af29187 437 Gene3D G3DSA:3.90.380.10 20 433 2.3E-100 T 14-10-2018 LH59_04865 e904199df00599239e4ca8586af29187 437 Gene3D G3DSA:2.102.10.10 40 171 2.3E-100 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 LH59_04865 e904199df00599239e4ca8586af29187 437 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 197 434 2.1E-13 T 14-10-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0044237|GO:0051537|GO:0055114 LH59_04865 e904199df00599239e4ca8586af29187 437 Pfam PF00355 Rieske [2Fe-2S] domain 42 126 1.8E-19 T 14-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 LH59_04865 e904199df00599239e4ca8586af29187 437 SUPERFAMILY SSF50022 10 161 3.27E-42 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 LH59_19630 e7e93370298d61b9bcd650ba05ba3ce7 260 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LH59_19630 e7e93370298d61b9bcd650ba05ba3ce7 260 Gene3D G3DSA:3.40.50.720 3 258 3.6E-79 T 14-10-2018 LH59_19630 e7e93370298d61b9bcd650ba05ba3ce7 260 SUPERFAMILY SSF51735 9 254 3.44E-76 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_19630 e7e93370298d61b9bcd650ba05ba3ce7 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.4E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_19630 e7e93370298d61b9bcd650ba05ba3ce7 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 1.4E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_19630 e7e93370298d61b9bcd650ba05ba3ce7 260 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.4E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_19630 e7e93370298d61b9bcd650ba05ba3ce7 260 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 254 4.3E-62 T 14-10-2018 LH59_19630 e7e93370298d61b9bcd650ba05ba3ce7 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 1.2E-35 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_19630 e7e93370298d61b9bcd650ba05ba3ce7 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.2E-35 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_19630 e7e93370298d61b9bcd650ba05ba3ce7 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 1.2E-35 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_19630 e7e93370298d61b9bcd650ba05ba3ce7 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.2E-35 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_19630 e7e93370298d61b9bcd650ba05ba3ce7 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.2E-35 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_19630 e7e93370298d61b9bcd650ba05ba3ce7 260 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.2E-35 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_22595 d878636125b11f5d8b15f36f4b38d566 678 Pfam PF02779 Transketolase, pyrimidine binding domain 358 541 6.2E-45 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain LH59_22595 d878636125b11f5d8b15f36f4b38d566 678 SUPERFAMILY SSF52922 551 678 1.96E-44 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 LH59_22595 d878636125b11f5d8b15f36f4b38d566 678 Gene3D G3DSA:3.40.50.970 331 554 1.5E-81 T 14-10-2018 LH59_22595 d878636125b11f5d8b15f36f4b38d566 678 ProSitePatterns PS00801 Transketolase signature 1. 16 36 - T 14-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 LH59_22595 d878636125b11f5d8b15f36f4b38d566 678 SUPERFAMILY SSF52518 352 544 5.89E-63 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold LH59_22595 d878636125b11f5d8b15f36f4b38d566 678 Gene3D G3DSA:3.40.50.970 9 330 1.5E-133 T 14-10-2018 LH59_22595 d878636125b11f5d8b15f36f4b38d566 678 Gene3D G3DSA:3.40.50.920 556 678 2.3E-44 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 LH59_22595 d878636125b11f5d8b15f36f4b38d566 678 Pfam PF02780 Transketolase, C-terminal domain 557 670 2.6E-18 T 14-10-2018 IPR033248 Transketolase, C-terminal domain LH59_22595 d878636125b11f5d8b15f36f4b38d566 678 TIGRFAM TIGR00232 tktlase_bact: transketolase 12 677 4.2E-285 T 14-10-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 LH59_22595 d878636125b11f5d8b15f36f4b38d566 678 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 11 338 1.7E-161 T 14-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 LH59_22595 d878636125b11f5d8b15f36f4b38d566 678 SUPERFAMILY SSF52518 10 323 1.31E-118 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold LH59_22595 d878636125b11f5d8b15f36f4b38d566 678 SMART SM00861 359 542 3.1E-67 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain LH59_00725 10b07a7a5b2e2829128038b7e9ae4b26 306 SUPERFAMILY SSF53850 91 281 1.72E-23 T 14-10-2018 LH59_00725 10b07a7a5b2e2829128038b7e9ae4b26 306 Gene3D G3DSA:1.10.10.10 1 84 2.6E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_00725 10b07a7a5b2e2829128038b7e9ae4b26 306 Pfam PF03466 LysR substrate binding domain 91 275 2.1E-24 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_00725 10b07a7a5b2e2829128038b7e9ae4b26 306 Gene3D G3DSA:3.40.190.10 160 251 1.2E-50 T 14-10-2018 LH59_00725 10b07a7a5b2e2829128038b7e9ae4b26 306 SUPERFAMILY SSF46785 2 85 2.39E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_00725 10b07a7a5b2e2829128038b7e9ae4b26 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 4.3E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_00725 10b07a7a5b2e2829128038b7e9ae4b26 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 4.3E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_00725 10b07a7a5b2e2829128038b7e9ae4b26 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 4.3E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_00725 10b07a7a5b2e2829128038b7e9ae4b26 306 Gene3D G3DSA:3.40.190.10 94 257 1.2E-50 T 14-10-2018 LH59_00725 10b07a7a5b2e2829128038b7e9ae4b26 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 8.7E-21 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_21750 f76ea4060aa9b78b51e0349d7ffce29a 199 Gene3D G3DSA:1.10.530.10 33 192 3.7E-12 T 14-10-2018 LH59_21750 f76ea4060aa9b78b51e0349d7ffce29a 199 SUPERFAMILY SSF53955 6 161 8.61E-25 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily LH59_12870 6efa7db141274ccce7b73b77289f055e 399 Gene3D G3DSA:2.160.20.10 34 311 7.2E-73 T 14-10-2018 IPR012334 Pectin lyase fold LH59_12870 6efa7db141274ccce7b73b77289f055e 399 SMART SM00656 65 274 4.4E-20 T 14-10-2018 IPR002022 Pectate lyase LH59_12870 6efa7db141274ccce7b73b77289f055e 399 PRINTS PR00807 Pollen allergen Amb family signature 98 114 8.1E-11 T 14-10-2018 IPR018082 AmbAllergen KEGG: 00040+4.2.2.2 LH59_12870 6efa7db141274ccce7b73b77289f055e 399 PRINTS PR00807 Pollen allergen Amb family signature 41 58 8.1E-11 T 14-10-2018 IPR018082 AmbAllergen KEGG: 00040+4.2.2.2 LH59_12870 6efa7db141274ccce7b73b77289f055e 399 PRINTS PR00807 Pollen allergen Amb family signature 251 270 8.1E-11 T 14-10-2018 IPR018082 AmbAllergen KEGG: 00040+4.2.2.2 LH59_12870 6efa7db141274ccce7b73b77289f055e 399 PRINTS PR00807 Pollen allergen Amb family signature 229 248 8.1E-11 T 14-10-2018 IPR018082 AmbAllergen KEGG: 00040+4.2.2.2 LH59_12870 6efa7db141274ccce7b73b77289f055e 399 SUPERFAMILY SSF51126 41 279 1.17E-60 T 14-10-2018 IPR011050 Pectin lyase fold/virulence factor LH59_12870 6efa7db141274ccce7b73b77289f055e 399 Pfam PF00544 Pectate lyase 97 268 1.0E-22 T 14-10-2018 IPR002022 Pectate lyase LH59_18100 99229885cf336e9149a58d303cda578d 266 Gene3D G3DSA:3.20.20.60 2 263 1.5E-94 T 14-10-2018 LH59_18100 99229885cf336e9149a58d303cda578d 266 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 18 243 5.4E-62 T 14-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 LH59_18100 99229885cf336e9149a58d303cda578d 266 SUPERFAMILY SSF51621 3 257 3.71E-84 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 LH59_18100 99229885cf336e9149a58d303cda578d 266 TIGRFAM TIGR02311 HpaI: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase 6 254 2.1E-120 T 14-10-2018 IPR012689 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase GO:0010124|GO:0018802 KEGG: 00350+4.1.2.52 LH59_21415 dd53d54dd1723232954fd8025bf6181b 339 Gene3D G3DSA:3.40.50.2300 63 315 4.4E-69 T 14-10-2018 LH59_21415 dd53d54dd1723232954fd8025bf6181b 339 Gene3D G3DSA:1.10.260.40 2 62 4.3E-23 T 14-10-2018 LH59_21415 dd53d54dd1723232954fd8025bf6181b 339 SMART SM00354 9 79 1.5E-24 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 LH59_21415 dd53d54dd1723232954fd8025bf6181b 339 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 11 21 4.3E-5 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 LH59_21415 dd53d54dd1723232954fd8025bf6181b 339 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 21 31 4.3E-5 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 LH59_21415 dd53d54dd1723232954fd8025bf6181b 339 ProSitePatterns PS00356 LacI-type HTH domain signature. 12 30 - T 14-10-2018 LH59_21415 dd53d54dd1723232954fd8025bf6181b 339 Pfam PF13377 Periplasmic binding protein-like domain 178 335 6.9E-37 T 14-10-2018 LH59_21415 dd53d54dd1723232954fd8025bf6181b 339 Pfam PF00356 Bacterial regulatory proteins, lacI family 11 56 9.5E-18 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 LH59_21415 dd53d54dd1723232954fd8025bf6181b 339 Gene3D G3DSA:3.40.50.2300 170 299 4.4E-69 T 14-10-2018 LH59_21415 dd53d54dd1723232954fd8025bf6181b 339 SUPERFAMILY SSF53822 70 338 4.86E-67 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_21415 dd53d54dd1723232954fd8025bf6181b 339 SUPERFAMILY SSF47413 10 67 1.18E-17 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 LH59_22300 ce6c2c44c73cc2b692e3b6809e0e2d15 226 Gene3D G3DSA:3.40.1080.10 1 223 1.3E-77 T 14-10-2018 LH59_22300 ce6c2c44c73cc2b692e3b6809e0e2d15 226 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 1 220 7.1E-109 T 14-10-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 LH59_22300 ce6c2c44c73cc2b692e3b6809e0e2d15 226 SUPERFAMILY SSF100950 2 221 1.67E-75 T 14-10-2018 IPR037171 NagB/RpiA transferase-like LH59_22300 ce6c2c44c73cc2b692e3b6809e0e2d15 226 Pfam PF01144 Coenzyme A transferase 7 217 8.2E-61 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 LH59_22300 ce6c2c44c73cc2b692e3b6809e0e2d15 226 SMART SM00882 6 219 5.0E-75 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 LH59_02370 e81b570af2b650666677844efacf9716 93 SMART SM00858 11 89 3.4E-10 T 14-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 LH59_02370 e81b570af2b650666677844efacf9716 93 Pfam PF08666 SAF domain 11 89 1.7E-5 T 14-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 LH59_02370 e81b570af2b650666677844efacf9716 93 Gene3D G3DSA:3.90.1210.30 4 92 7.9E-24 T 14-10-2018 LH59_26130 5fe4a1962c1a14d4cb8a89626bb15797 275 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 19 266 1.5E-90 T 14-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 LH59_26130 5fe4a1962c1a14d4cb8a89626bb15797 275 Pfam PF05175 Methyltransferase small domain 99 186 3.6E-14 T 14-10-2018 IPR007848 Methyltransferase small domain GO:0008168 LH59_26130 5fe4a1962c1a14d4cb8a89626bb15797 275 Gene3D G3DSA:1.10.8.10 1 78 7.8E-21 T 14-10-2018 LH59_26130 5fe4a1962c1a14d4cb8a89626bb15797 275 Gene3D G3DSA:3.40.50.150 79 270 1.3E-56 T 14-10-2018 LH59_26130 5fe4a1962c1a14d4cb8a89626bb15797 275 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 176 182 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 LH59_26130 5fe4a1962c1a14d4cb8a89626bb15797 275 SUPERFAMILY SSF53335 5 269 4.29E-54 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_26130 5fe4a1962c1a14d4cb8a89626bb15797 275 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 1 271 45.032 T 14-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 LH59_26130 5fe4a1962c1a14d4cb8a89626bb15797 275 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 14 270 3.0E-72 T 14-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 LH59_10325 34f69d0c3ccafc27aba2be12ddfbd970 345 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 69 330 1.2E-23 T 14-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 LH59_10325 34f69d0c3ccafc27aba2be12ddfbd970 345 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 123 298 2.0E-56 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 LH59_10325 34f69d0c3ccafc27aba2be12ddfbd970 345 SUPERFAMILY SSF52283 66 142 1.23E-20 T 14-10-2018 LH59_10325 34f69d0c3ccafc27aba2be12ddfbd970 345 Gene3D G3DSA:3.40.50.720 47 322 2.3E-92 T 14-10-2018 LH59_10325 34f69d0c3ccafc27aba2be12ddfbd970 345 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 208 230 - T 14-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site LH59_10325 34f69d0c3ccafc27aba2be12ddfbd970 345 SUPERFAMILY SSF51735 116 299 9.87E-54 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_10325 34f69d0c3ccafc27aba2be12ddfbd970 345 Gene3D G3DSA:3.40.50.720 113 296 2.3E-92 T 14-10-2018 LH59_23175 13c031dc5122b2dfd9681ab75c34aa62 332 Pfam PF01032 FecCD transport family 18 327 2.8E-83 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 LH59_23175 13c031dc5122b2dfd9681ab75c34aa62 332 SUPERFAMILY SSF81345 3 327 5.89E-77 T 14-10-2018 IPR037294 ABC transporter, BtuC-like LH59_23175 13c031dc5122b2dfd9681ab75c34aa62 332 Gene3D G3DSA:1.10.3470.10 4 332 5.0E-96 T 14-10-2018 IPR037294 ABC transporter, BtuC-like LH59_14770 132ffd404773b4937267f1c37082d342 472 Pfam PF17200 Single Cache domain 2 48 192 4.3E-39 T 14-10-2018 IPR033480 Single Cache domain 2 LH59_14770 132ffd404773b4937267f1c37082d342 472 Pfam PF07730 Histidine kinase 251 325 4.5E-17 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 LH59_14770 132ffd404773b4937267f1c37082d342 472 SMART SM00387 368 463 3.8E-8 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_14770 132ffd404773b4937267f1c37082d342 472 SUPERFAMILY SSF55874 364 461 1.01E-15 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_14770 132ffd404773b4937267f1c37082d342 472 Gene3D G3DSA:3.30.450.20 38 184 5.1E-42 T 14-10-2018 LH59_14770 132ffd404773b4937267f1c37082d342 472 PIRSF PIRSF037314 1 471 3.1E-175 T 14-10-2018 IPR017171 Signal transduction histidine kinase, MctS LH59_14770 132ffd404773b4937267f1c37082d342 472 Gene3D G3DSA:3.30.565.10 345 461 2.3E-30 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_14770 132ffd404773b4937267f1c37082d342 472 SMART SM01049 42 131 2.2E-32 T 14-10-2018 IPR033480 Single Cache domain 2 LH59_14770 132ffd404773b4937267f1c37082d342 472 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 371 462 4.0E-7 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_02025 d57e8a9fe354a8e3eb89a2f6a8b4fc00 466 SUPERFAMILY SSF52540 82 352 4.46E-89 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_02025 d57e8a9fe354a8e3eb89a2f6a8b4fc00 466 SUPERFAMILY SSF47917 350 465 3.92E-54 T 14-10-2018 LH59_02025 d57e8a9fe354a8e3eb89a2f6a8b4fc00 466 Gene3D G3DSA:1.10.1140.10 350 466 6.4E-59 T 14-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 LH59_02025 d57e8a9fe354a8e3eb89a2f6a8b4fc00 466 Gene3D G3DSA:3.40.50.300 81 349 4.7E-112 T 14-10-2018 LH59_02025 d57e8a9fe354a8e3eb89a2f6a8b4fc00 466 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 78 3.0E-18 T 14-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 LH59_02025 d57e8a9fe354a8e3eb89a2f6a8b4fc00 466 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 135 347 4.0E-64 T 14-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 LH59_02025 d57e8a9fe354a8e3eb89a2f6a8b4fc00 466 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 465 56.341 T 14-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 LH59_02025 d57e8a9fe354a8e3eb89a2f6a8b4fc00 466 SMART SM00382 147 324 0.0037 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_02025 d57e8a9fe354a8e3eb89a2f6a8b4fc00 466 Gene3D G3DSA:2.40.10.170 1 80 1.1E-27 T 14-10-2018 LH59_02025 d57e8a9fe354a8e3eb89a2f6a8b4fc00 466 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 338 347 - T 14-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 LH59_02025 d57e8a9fe354a8e3eb89a2f6a8b4fc00 466 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 465 6.5E-249 T 14-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 LH59_02025 d57e8a9fe354a8e3eb89a2f6a8b4fc00 466 SUPERFAMILY SSF50615 3 80 2.17E-24 T 14-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 LH59_09355 6ec9ca759cc76ee0d5ed64c268af3ec0 654 SUPERFAMILY SSF55073 239 393 2.67E-18 T 14-10-2018 IPR029787 Nucleotide cyclase LH59_09355 6ec9ca759cc76ee0d5ed64c268af3ec0 654 Gene3D G3DSA:3.30.70.270 216 393 2.2E-26 T 14-10-2018 LH59_09355 6ec9ca759cc76ee0d5ed64c268af3ec0 654 SMART SM00267 222 395 1.2E-10 T 14-10-2018 IPR000160 GGDEF domain LH59_09355 6ec9ca759cc76ee0d5ed64c268af3ec0 654 Gene3D G3DSA:3.20.20.450 404 640 1.4E-35 T 14-10-2018 IPR035919 EAL domain superfamily LH59_09355 6ec9ca759cc76ee0d5ed64c268af3ec0 654 Pfam PF00990 Diguanylate cyclase, GGDEF domain 234 387 6.8E-16 T 14-10-2018 IPR000160 GGDEF domain LH59_09355 6ec9ca759cc76ee0d5ed64c268af3ec0 654 Pfam PF16448 LapD/MoxY periplasmic domain 27 147 7.9E-10 T 14-10-2018 IPR032244 LapD/MoxY, periplasmic domain LH59_09355 6ec9ca759cc76ee0d5ed64c268af3ec0 654 SMART SM00052 405 636 3.6E-10 T 14-10-2018 IPR001633 EAL domain LH59_09355 6ec9ca759cc76ee0d5ed64c268af3ec0 654 Pfam PF00563 EAL domain 411 635 1.3E-31 T 14-10-2018 IPR001633 EAL domain LH59_09355 6ec9ca759cc76ee0d5ed64c268af3ec0 654 SUPERFAMILY SSF141868 411 637 2.48E-31 T 14-10-2018 IPR035919 EAL domain superfamily LH59_25935 31aeda6c7ed9e36e92079af57b3bfb25 260 Gene3D G3DSA:1.10.10.10 2 80 4.3E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_25935 31aeda6c7ed9e36e92079af57b3bfb25 260 Gene3D G3DSA:3.30.450.40 81 259 3.9E-59 T 14-10-2018 IPR029016 GAF-like domain superfamily LH59_25935 31aeda6c7ed9e36e92079af57b3bfb25 260 SUPERFAMILY SSF55781 78 257 1.08E-51 T 14-10-2018 LH59_25935 31aeda6c7ed9e36e92079af57b3bfb25 260 SMART SM00346 14 102 1.8E-25 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_25935 31aeda6c7ed9e36e92079af57b3bfb25 260 TIGRFAM TIGR02431 pcaR_pcaU: beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family 11 257 2.6E-107 T 14-10-2018 IPR012794 Beta-ketoadipate transcriptional regulator, PcaR/PcaU/PobR GO:0003677|GO:0045893|GO:0046278 LH59_25935 31aeda6c7ed9e36e92079af57b3bfb25 260 Pfam PF09339 IclR helix-turn-helix domain 18 64 6.8E-14 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_25935 31aeda6c7ed9e36e92079af57b3bfb25 260 SUPERFAMILY SSF46785 14 85 7.87E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_25935 31aeda6c7ed9e36e92079af57b3bfb25 260 Pfam PF01614 Bacterial transcriptional regulator 129 255 1.6E-34 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal LH59_26985 3e61a9b1f26dbc8bc866dbc79b6ec77a 1881 Gene3D G3DSA:2.160.20.10 32 326 1.6E-94 T 14-10-2018 IPR012334 Pectin lyase fold LH59_26985 3e61a9b1f26dbc8bc866dbc79b6ec77a 1881 Pfam PF13332 Haemagluttinin repeat 1631 1784 5.2E-15 T 14-10-2018 IPR025157 Hemagglutinin repeat LH59_26985 3e61a9b1f26dbc8bc866dbc79b6ec77a 1881 Pfam PF13332 Haemagluttinin repeat 1556 1622 3.2E-9 T 14-10-2018 IPR025157 Hemagglutinin repeat LH59_26985 3e61a9b1f26dbc8bc866dbc79b6ec77a 1881 TIGRFAM TIGR01901 adhes_NPXG: filamentous hemagglutinin family N-terminal domain 63 159 1.8E-21 T 14-10-2018 IPR008638 Filamentous haemagglutinin, N-terminal LH59_26985 3e61a9b1f26dbc8bc866dbc79b6ec77a 1881 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 1405 1442 0.84 T 14-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat LH59_26985 3e61a9b1f26dbc8bc866dbc79b6ec77a 1881 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 716 754 5.3E-4 T 14-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat LH59_26985 3e61a9b1f26dbc8bc866dbc79b6ec77a 1881 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 543 579 0.33 T 14-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat LH59_26985 3e61a9b1f26dbc8bc866dbc79b6ec77a 1881 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 500 539 2.3E-7 T 14-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat LH59_26985 3e61a9b1f26dbc8bc866dbc79b6ec77a 1881 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 423 458 4.7E-5 T 14-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat LH59_26985 3e61a9b1f26dbc8bc866dbc79b6ec77a 1881 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 398 421 2.5 T 14-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat LH59_26985 3e61a9b1f26dbc8bc866dbc79b6ec77a 1881 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 459 499 3.0E-4 T 14-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat LH59_26985 3e61a9b1f26dbc8bc866dbc79b6ec77a 1881 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 359 393 0.0072 T 14-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat LH59_26985 3e61a9b1f26dbc8bc866dbc79b6ec77a 1881 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 565 598 0.018 T 14-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat LH59_26985 3e61a9b1f26dbc8bc866dbc79b6ec77a 1881 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 378 418 0.0051 T 14-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat LH59_26985 3e61a9b1f26dbc8bc866dbc79b6ec77a 1881 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 601 640 4.6E-8 T 14-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat LH59_26985 3e61a9b1f26dbc8bc866dbc79b6ec77a 1881 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 622 659 2.8E-5 T 14-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat LH59_26985 3e61a9b1f26dbc8bc866dbc79b6ec77a 1881 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 290 328 0.8 T 14-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat LH59_26985 3e61a9b1f26dbc8bc866dbc79b6ec77a 1881 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 836 865 0.89 T 14-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat LH59_26985 3e61a9b1f26dbc8bc866dbc79b6ec77a 1881 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 681 714 2.7E-6 T 14-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat LH59_26985 3e61a9b1f26dbc8bc866dbc79b6ec77a 1881 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 755 776 0.0021 T 14-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat LH59_26985 3e61a9b1f26dbc8bc866dbc79b6ec77a 1881 TIGRFAM TIGR01731 fil_hemag_20aa: adhesin HecA family 20-residue repeat (two copies) 525 560 0.031 T 14-10-2018 IPR010069 Filamentous haemagglutinin, 20-residue x2 repeat LH59_26985 3e61a9b1f26dbc8bc866dbc79b6ec77a 1881 SMART SM00912 44 164 2.0E-43 T 14-10-2018 IPR008638 Filamentous haemagglutinin, N-terminal LH59_26985 3e61a9b1f26dbc8bc866dbc79b6ec77a 1881 Pfam PF05860 haemagglutination activity domain 38 161 3.7E-32 T 14-10-2018 IPR008638 Filamentous haemagglutinin, N-terminal LH59_26985 3e61a9b1f26dbc8bc866dbc79b6ec77a 1881 Pfam PF05594 Haemagluttinin repeat 454 520 0.033 T 14-10-2018 IPR008619 Filamentous haemagglutinin repeat LH59_26985 3e61a9b1f26dbc8bc866dbc79b6ec77a 1881 Pfam PF05594 Haemagluttinin repeat 688 763 21.0 T 14-10-2018 IPR008619 Filamentous haemagglutinin repeat LH59_26985 3e61a9b1f26dbc8bc866dbc79b6ec77a 1881 Pfam PF05594 Haemagluttinin repeat 271 329 0.09 T 14-10-2018 IPR008619 Filamentous haemagglutinin repeat LH59_26985 3e61a9b1f26dbc8bc866dbc79b6ec77a 1881 Pfam PF05594 Haemagluttinin repeat 583 640 1.1E-4 T 14-10-2018 IPR008619 Filamentous haemagglutinin repeat LH59_26985 3e61a9b1f26dbc8bc866dbc79b6ec77a 1881 Pfam PF05594 Haemagluttinin repeat 1399 1462 0.021 T 14-10-2018 IPR008619 Filamentous haemagglutinin repeat LH59_26985 3e61a9b1f26dbc8bc866dbc79b6ec77a 1881 Pfam PF05594 Haemagluttinin repeat 365 418 0.0093 T 14-10-2018 IPR008619 Filamentous haemagglutinin repeat LH59_26985 3e61a9b1f26dbc8bc866dbc79b6ec77a 1881 SUPERFAMILY SSF51126 40 312 1.1E-60 T 14-10-2018 IPR011050 Pectin lyase fold/virulence factor LH59_04840 eca901caa2e3cca5d5e054d84d24ab1b 261 Gene3D G3DSA:3.50.30.50 1 261 5.2E-89 T 14-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 LH59_04840 eca901caa2e3cca5d5e054d84d24ab1b 261 SUPERFAMILY SSF102198 18 257 6.93E-52 T 14-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 LH59_04840 eca901caa2e3cca5d5e054d84d24ab1b 261 Pfam PF04199 Putative cyclase 21 197 3.3E-30 T 14-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 LH59_22565 0de2cdef243309c8c1e81648d1f8d9bc 394 Gene3D G3DSA:3.30.420.40 201 394 6.7E-65 T 14-10-2018 LH59_22565 0de2cdef243309c8c1e81648d1f8d9bc 394 SUPERFAMILY SSF53067 4 198 2.07E-56 T 14-10-2018 LH59_22565 0de2cdef243309c8c1e81648d1f8d9bc 394 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 205 222 - T 14-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 LH59_22565 0de2cdef243309c8c1e81648d1f8d9bc 394 SUPERFAMILY SSF53067 161 391 2.59E-73 T 14-10-2018 LH59_22565 0de2cdef243309c8c1e81648d1f8d9bc 394 PIRSF PIRSF000722 1 394 6.3E-132 T 14-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 LH59_22565 0de2cdef243309c8c1e81648d1f8d9bc 394 TIGRFAM TIGR00016 ackA: acetate kinase 2 391 7.0E-101 T 14-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 LH59_22565 0de2cdef243309c8c1e81648d1f8d9bc 394 Gene3D G3DSA:3.30.420.40 4 197 1.7E-58 T 14-10-2018 LH59_22565 0de2cdef243309c8c1e81648d1f8d9bc 394 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 5 16 - T 14-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 LH59_22565 0de2cdef243309c8c1e81648d1f8d9bc 394 Pfam PF00871 Acetokinase family 5 385 1.7E-100 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 LH59_22565 0de2cdef243309c8c1e81648d1f8d9bc 394 PRINTS PR00471 Acetate kinase family signature 205 226 1.3E-36 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 LH59_22565 0de2cdef243309c8c1e81648d1f8d9bc 394 PRINTS PR00471 Acetate kinase family signature 176 189 1.3E-36 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 LH59_22565 0de2cdef243309c8c1e81648d1f8d9bc 394 PRINTS PR00471 Acetate kinase family signature 298 311 1.3E-36 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 LH59_22565 0de2cdef243309c8c1e81648d1f8d9bc 394 PRINTS PR00471 Acetate kinase family signature 320 336 1.3E-36 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 LH59_22565 0de2cdef243309c8c1e81648d1f8d9bc 394 PRINTS PR00471 Acetate kinase family signature 372 384 1.3E-36 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 LH59_22565 0de2cdef243309c8c1e81648d1f8d9bc 394 PRINTS PR00471 Acetate kinase family signature 5 16 1.3E-36 T 14-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 LH59_22565 0de2cdef243309c8c1e81648d1f8d9bc 394 Hamap MF_00020 Acetate kinase [ackA]. 1 394 151.251 T 14-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 LH59_12925 c261fc5ef50e76ed64b4e2a1058a51a3 277 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 7 271 2.3E-74 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 LH59_12925 c261fc5ef50e76ed64b4e2a1058a51a3 277 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 7 99 1.0E-14 T 14-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal LH59_12925 c261fc5ef50e76ed64b4e2a1058a51a3 277 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 226 249 - T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 LH59_12925 c261fc5ef50e76ed64b4e2a1058a51a3 277 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 169 271 1.1E-32 T 14-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 LH59_12925 c261fc5ef50e76ed64b4e2a1058a51a3 277 SUPERFAMILY SSF51735 7 164 9.05E-31 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_12925 c261fc5ef50e76ed64b4e2a1058a51a3 277 Gene3D G3DSA:3.40.50.720 1 168 6.1E-42 T 14-10-2018 LH59_12925 c261fc5ef50e76ed64b4e2a1058a51a3 277 SUPERFAMILY SSF48179 167 275 2.21E-32 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 LH59_12925 c261fc5ef50e76ed64b4e2a1058a51a3 277 PIRSF PIRSF000193 4 274 3.4E-69 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 LH59_12925 c261fc5ef50e76ed64b4e2a1058a51a3 277 Gene3D G3DSA:1.10.3730.10 169 276 3.3E-38 T 14-10-2018 LH59_12925 c261fc5ef50e76ed64b4e2a1058a51a3 277 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 5 271 25.431 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 LH59_13350 849f4d93a771556accc1fbadfd5f3959 411 Gene3D G3DSA:3.30.420.380 23 161 1.5E-12 T 14-10-2018 LH59_13350 849f4d93a771556accc1fbadfd5f3959 411 Pfam PF05134 Type II secretion system (T2SS), protein L 45 169 1.0E-8 T 14-10-2018 IPR024230 GspL, cytoplasmic actin-ATPase-like domain LH59_13350 849f4d93a771556accc1fbadfd5f3959 411 Pfam PF12693 GspL periplasmic domain 245 353 1.0E-13 T 14-10-2018 IPR025691 GspL periplasmic domain LH59_13350 849f4d93a771556accc1fbadfd5f3959 411 SUPERFAMILY SSF53067 6 141 7.25E-13 T 14-10-2018 LH59_14820 f35efbb60648fcfe2c3044ed7661b928 330 Pfam PF04773 FecR protein 120 213 5.8E-17 T 14-10-2018 IPR006860 FecR protein LH59_14820 f35efbb60648fcfe2c3044ed7661b928 330 PIRSF PIRSF018266 6 328 7.8E-79 T 14-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component LH59_14820 f35efbb60648fcfe2c3044ed7661b928 330 Gene3D G3DSA:2.60.120.1440 107 238 6.5E-14 T 14-10-2018 LH59_14820 f35efbb60648fcfe2c3044ed7661b928 330 Pfam PF16220 Domain of unknown function (DUF4880) 13 55 2.4E-13 T 14-10-2018 IPR032623 FecR, N-terminal LH59_09150 ac98dffb977aeefe5c8686dc954a4050 141 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 3 138 35.292 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 LH59_09150 ac98dffb977aeefe5c8686dc954a4050 141 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 114 122 - T 14-10-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 LH59_09150 ac98dffb977aeefe5c8686dc954a4050 141 Gene3D G3DSA:3.30.70.141 1 141 1.6E-59 T 14-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 LH59_09150 ac98dffb977aeefe5c8686dc954a4050 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 6.5E-40 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 LH59_09150 ac98dffb977aeefe5c8686dc954a4050 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 6.5E-40 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 LH59_09150 ac98dffb977aeefe5c8686dc954a4050 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 6 28 6.5E-40 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 LH59_09150 ac98dffb977aeefe5c8686dc954a4050 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 6.5E-40 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 LH59_09150 ac98dffb977aeefe5c8686dc954a4050 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 6.5E-40 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 LH59_09150 ac98dffb977aeefe5c8686dc954a4050 141 SMART SM00562 3 140 1.2E-83 T 14-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 LH59_09150 ac98dffb977aeefe5c8686dc954a4050 141 Pfam PF00334 Nucleoside diphosphate kinase 4 136 2.0E-54 T 14-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 LH59_09150 ac98dffb977aeefe5c8686dc954a4050 141 SUPERFAMILY SSF54919 1 139 4.19E-56 T 14-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 LH59_26010 cd565408ea251a281ef1f4695308b07f 254 SMART SM00382 31 226 1.1E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_26010 cd565408ea251a281ef1f4695308b07f 254 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 226 248 3.5E-14 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal LH59_26010 cd565408ea251a281ef1f4695308b07f 254 SUPERFAMILY SSF52540 5 248 9.78E-64 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_26010 cd565408ea251a281ef1f4695308b07f 254 Pfam PF00005 ABC transporter 23 176 1.7E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_26010 cd565408ea251a281ef1f4695308b07f 254 Gene3D G3DSA:3.40.50.300 2 249 3.6E-61 T 14-10-2018 LH59_03400 c60085340e7afafec4faa91edd7c264a 409 SUPERFAMILY SSF55174 327 404 5.63E-19 T 14-10-2018 LH59_03400 c60085340e7afafec4faa91edd7c264a 409 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 54 64 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 LH59_03400 c60085340e7afafec4faa91edd7c264a 409 SMART SM00363 347 408 4.4E-5 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_03400 c60085340e7afafec4faa91edd7c264a 409 Gene3D G3DSA:3.40.50.620 11 230 7.7E-70 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LH59_03400 c60085340e7afafec4faa91edd7c264a 409 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 13 407 4.0E-120 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 LH59_03400 c60085340e7afafec4faa91edd7c264a 409 Pfam PF01479 S4 domain 349 391 1.3E-7 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_03400 c60085340e7afafec4faa91edd7c264a 409 Hamap MF_02007 Tyrosine--tRNA ligase [tyrS]. 10 407 47.989 T 14-10-2018 IPR024108 Tyrosine-tRNA ligase, bacterial-type, type 2 GO:0004831 KEGG: 00970+6.1.1.1 LH59_03400 c60085340e7afafec4faa91edd7c264a 409 SUPERFAMILY SSF52374 18 328 5.91E-89 T 14-10-2018 LH59_03400 c60085340e7afafec4faa91edd7c264a 409 Gene3D G3DSA:1.10.240.10 231 337 1.3E-33 T 14-10-2018 LH59_03400 c60085340e7afafec4faa91edd7c264a 409 Gene3D G3DSA:3.10.290.10 338 407 4.9E-18 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 LH59_03400 c60085340e7afafec4faa91edd7c264a 409 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 223 235 1.4E-25 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 LH59_03400 c60085340e7afafec4faa91edd7c264a 409 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 173 188 1.4E-25 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 LH59_03400 c60085340e7afafec4faa91edd7c264a 409 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 58 80 1.4E-25 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 LH59_03400 c60085340e7afafec4faa91edd7c264a 409 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 190 212 1.4E-25 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 LH59_03400 c60085340e7afafec4faa91edd7c264a 409 Pfam PF00579 tRNA synthetases class I (W and Y) 45 328 9.4E-74 T 14-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 LH59_06155 057a90ebfc4d1d5359a6d05e5b923619 102 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 1 102 21.039 T 14-10-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 LH59_06155 057a90ebfc4d1d5359a6d05e5b923619 102 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 8 98 6.9E-25 T 14-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like LH59_12295 392cbbf9c06dc8518eb0253d96325bd1 392 Gene3D G3DSA:1.20.1250.20 6 385 6.1E-27 T 14-10-2018 LH59_12295 392cbbf9c06dc8518eb0253d96325bd1 392 Hamap MF_01118 Uncharacterized MFS-type transporter YhhS [yhhS]. 2 387 43.517 T 14-10-2018 IPR023008 Uncharacterized MFS-type transporter YhhS-like LH59_12295 392cbbf9c06dc8518eb0253d96325bd1 392 Pfam PF07690 Major Facilitator Superfamily 13 185 3.3E-12 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_12295 392cbbf9c06dc8518eb0253d96325bd1 392 SUPERFAMILY SSF103473 10 384 2.35E-36 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_20690 3b67e9947b4a1c9e3a17b100a3fbc5e6 211 SMART SM00470 52 150 2.9E-4 T 14-10-2018 IPR003115 ParB/Sulfiredoxin LH59_20690 3b67e9947b4a1c9e3a17b100a3fbc5e6 211 Pfam PF02195 ParB-like nuclease domain 53 149 2.2E-10 T 14-10-2018 IPR003115 ParB/Sulfiredoxin LH59_20690 3b67e9947b4a1c9e3a17b100a3fbc5e6 211 SUPERFAMILY SSF110849 50 191 2.96E-19 T 14-10-2018 IPR036086 ParB/Sulfiredoxin superfamily LH59_08505 c745a7aeca693f692bd579c71c350d1a 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 5.9E-19 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 LH59_08505 c745a7aeca693f692bd579c71c350d1a 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 5.9E-19 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 LH59_08505 c745a7aeca693f692bd579c71c350d1a 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 5.9E-19 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 LH59_08505 c745a7aeca693f692bd579c71c350d1a 90 SMART SM00411 1 90 8.0E-40 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 LH59_08505 c745a7aeca693f692bd579c71c350d1a 90 Gene3D G3DSA:4.10.520.10 1 90 2.7E-36 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 LH59_08505 c745a7aeca693f692bd579c71c350d1a 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 6.7E-34 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 LH59_08505 c745a7aeca693f692bd579c71c350d1a 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 14-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 LH59_08505 c745a7aeca693f692bd579c71c350d1a 90 SUPERFAMILY SSF47729 1 90 8.54E-33 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 LH59_11560 6959f1180ca415c09e989bd73c2b0524 142 Pfam PF02561 Flagellar protein FliS 23 131 5.0E-33 T 14-10-2018 IPR003713 Flagellar protein FliS GO:0044780 LH59_11560 6959f1180ca415c09e989bd73c2b0524 142 TIGRFAM TIGR00208 fliS: flagellar protein FliS 15 134 3.7E-24 T 14-10-2018 IPR003713 Flagellar protein FliS GO:0044780 LH59_11560 6959f1180ca415c09e989bd73c2b0524 142 SUPERFAMILY SSF101116 16 131 1.7E-32 T 14-10-2018 IPR036584 Flagellar protein FliS superfamily GO:0044780 LH59_11560 6959f1180ca415c09e989bd73c2b0524 142 PIRSF PIRSF039090 9 141 1.3E-33 T 14-10-2018 IPR003713 Flagellar protein FliS GO:0044780 LH59_11560 6959f1180ca415c09e989bd73c2b0524 142 Gene3D G3DSA:1.20.120.340 8 134 4.8E-34 T 14-10-2018 LH59_11215 728f96ac181f8d6be970a1cdaf40e1ea 204 Gene3D G3DSA:3.40.30.10 41 198 1.4E-46 T 14-10-2018 LH59_11215 728f96ac181f8d6be970a1cdaf40e1ea 204 Pfam PF02630 SCO1/SenC 44 179 6.4E-38 T 14-10-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_11215 728f96ac181f8d6be970a1cdaf40e1ea 204 SUPERFAMILY SSF52833 44 201 4.56E-46 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_23870 9a0d8d63e395d7b0febb401b2407dd7c 150 Gene3D G3DSA:3.40.630.30 1 148 3.2E-22 T 14-10-2018 LH59_23870 9a0d8d63e395d7b0febb401b2407dd7c 150 Pfam PF13673 Acetyltransferase (GNAT) domain 30 138 3.7E-11 T 14-10-2018 IPR000182 GNAT domain LH59_23870 9a0d8d63e395d7b0febb401b2407dd7c 150 SUPERFAMILY SSF55729 1 138 2.92E-22 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_05345 3f5462b32a76b9cdab2f5952c179c2d2 172 SUPERFAMILY SSF55729 8 164 4.82E-30 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_05345 3f5462b32a76b9cdab2f5952c179c2d2 172 Gene3D G3DSA:3.40.630.30 1 172 1.2E-49 T 14-10-2018 LH59_05345 3f5462b32a76b9cdab2f5952c179c2d2 172 Pfam PF00583 Acetyltransferase (GNAT) family 31 137 8.1E-16 T 14-10-2018 IPR000182 GNAT domain LH59_00290 a378ec7088ebb77551e9900fc14823ec 239 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 19 221 40.896 T 14-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 LH59_00290 a378ec7088ebb77551e9900fc14823ec 239 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 26 215 3.0E-75 T 14-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 LH59_00290 a378ec7088ebb77551e9900fc14823ec 239 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 23 216 1.5E-67 T 14-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 LH59_00290 a378ec7088ebb77551e9900fc14823ec 239 Gene3D G3DSA:3.90.870.10 14 223 6.6E-79 T 14-10-2018 LH59_00290 a378ec7088ebb77551e9900fc14823ec 239 SUPERFAMILY SSF55821 21 219 1.01E-76 T 14-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily LH59_13525 1ae53db0cbb0b4a03e0fce00ef8106eb 337 Pfam PF13379 NMT1-like family 46 249 2.0E-20 T 14-10-2018 LH59_13525 1ae53db0cbb0b4a03e0fce00ef8106eb 337 Gene3D G3DSA:3.40.190.10 109 209 2.1E-44 T 14-10-2018 LH59_13525 1ae53db0cbb0b4a03e0fce00ef8106eb 337 SMART SM00062 31 247 0.0052 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_13525 1ae53db0cbb0b4a03e0fce00ef8106eb 337 Gene3D G3DSA:1.10.8.450 241 273 2.1E-44 T 14-10-2018 LH59_13525 1ae53db0cbb0b4a03e0fce00ef8106eb 337 SUPERFAMILY SSF53850 30 251 2.18E-39 T 14-10-2018 LH59_13525 1ae53db0cbb0b4a03e0fce00ef8106eb 337 Gene3D G3DSA:3.40.190.10 43 240 2.1E-44 T 14-10-2018 LH59_00195 113fa2542b58ccc4ca4d51d4d2dd4adc 266 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 254 5.0E-16 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_00195 113fa2542b58ccc4ca4d51d4d2dd4adc 266 SUPERFAMILY SSF161098 9 255 5.14E-57 T 14-10-2018 IPR035906 MetI-like superfamily LH59_00195 113fa2542b58ccc4ca4d51d4d2dd4adc 266 Gene3D G3DSA:1.10.3720.10 8 264 5.2E-55 T 14-10-2018 IPR035906 MetI-like superfamily LH59_09715 e22d83e12f7a0696e8fe6ba744648733 464 Gene3D G3DSA:1.20.1250.20 261 458 1.6E-21 T 14-10-2018 LH59_09715 e22d83e12f7a0696e8fe6ba744648733 464 Gene3D G3DSA:1.20.1720.10 19 221 3.4E-43 T 14-10-2018 LH59_09715 e22d83e12f7a0696e8fe6ba744648733 464 PRINTS PR01036 Tetracycline resistance protein TetB signature 142 166 2.6E-7 T 14-10-2018 LH59_09715 e22d83e12f7a0696e8fe6ba744648733 464 PRINTS PR01036 Tetracycline resistance protein TetB signature 21 45 2.6E-7 T 14-10-2018 LH59_09715 e22d83e12f7a0696e8fe6ba744648733 464 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 18 418 2.0E-76 T 14-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 LH59_09715 e22d83e12f7a0696e8fe6ba744648733 464 SUPERFAMILY SSF103473 11 461 6.02E-61 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_09715 e22d83e12f7a0696e8fe6ba744648733 464 Pfam PF07690 Major Facilitator Superfamily 22 411 8.4E-53 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_16135 5b2d6e03eaee51c330f509d2d7da629d 296 Gene3D G3DSA:3.40.190.10 91 285 2.0E-56 T 14-10-2018 LH59_16135 5b2d6e03eaee51c330f509d2d7da629d 296 Pfam PF03466 LysR substrate binding domain 87 292 9.8E-42 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_16135 5b2d6e03eaee51c330f509d2d7da629d 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.0E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_16135 5b2d6e03eaee51c330f509d2d7da629d 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.0E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_16135 5b2d6e03eaee51c330f509d2d7da629d 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.0E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_16135 5b2d6e03eaee51c330f509d2d7da629d 296 Gene3D G3DSA:3.40.190.10 162 267 2.0E-56 T 14-10-2018 LH59_16135 5b2d6e03eaee51c330f509d2d7da629d 296 Gene3D G3DSA:1.10.10.10 1 90 7.8E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_16135 5b2d6e03eaee51c330f509d2d7da629d 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.9E-21 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_16135 5b2d6e03eaee51c330f509d2d7da629d 296 SUPERFAMILY SSF53850 87 294 3.26E-38 T 14-10-2018 LH59_16135 5b2d6e03eaee51c330f509d2d7da629d 296 SUPERFAMILY SSF46785 1 85 7.4E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_06680 744031c15537f8a0e9f28d9a5929b91f 282 Pfam PF00892 EamA-like transporter family 3 126 1.5E-21 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_06680 744031c15537f8a0e9f28d9a5929b91f 282 Pfam PF00892 EamA-like transporter family 137 273 4.3E-27 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_06680 744031c15537f8a0e9f28d9a5929b91f 282 SUPERFAMILY SSF103481 173 275 3.14E-16 T 14-10-2018 LH59_06680 744031c15537f8a0e9f28d9a5929b91f 282 SUPERFAMILY SSF103481 31 127 1.96E-14 T 14-10-2018 LH59_05695 92584702ef6f427160d1328f18829ce1 313 Gene3D G3DSA:3.40.190.10 174 272 1.2E-37 T 14-10-2018 LH59_05695 92584702ef6f427160d1328f18829ce1 313 Gene3D G3DSA:3.40.190.10 100 289 1.2E-37 T 14-10-2018 LH59_05695 92584702ef6f427160d1328f18829ce1 313 SUPERFAMILY SSF46785 8 88 9.52E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_05695 92584702ef6f427160d1328f18829ce1 313 SUPERFAMILY SSF53850 99 292 1.97E-30 T 14-10-2018 LH59_05695 92584702ef6f427160d1328f18829ce1 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 66 3.5E-16 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_05695 92584702ef6f427160d1328f18829ce1 313 Gene3D G3DSA:1.10.10.10 2 92 6.0E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_05695 92584702ef6f427160d1328f18829ce1 313 Pfam PF03466 LysR substrate binding domain 100 292 2.4E-20 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_04315 29e3a647a9f93b31aaf4275aa2c4421e 207 Gene3D G3DSA:3.40.50.360 1 207 1.3E-40 T 14-10-2018 IPR029039 Flavoprotein-like superfamily LH59_04315 29e3a647a9f93b31aaf4275aa2c4421e 207 Pfam PF02525 Flavodoxin-like fold 1 200 8.1E-30 T 14-10-2018 IPR003680 Flavodoxin-like fold LH59_04315 29e3a647a9f93b31aaf4275aa2c4421e 207 SUPERFAMILY SSF52218 1 203 5.8E-32 T 14-10-2018 IPR029039 Flavoprotein-like superfamily LH59_04315 29e3a647a9f93b31aaf4275aa2c4421e 207 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 1 204 21.974 T 14-10-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 LH59_23620 06bc57d095155d7e1019b40eee166733 261 Pfam PF12833 Helix-turn-helix domain 183 257 1.9E-20 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_23620 06bc57d095155d7e1019b40eee166733 261 SMART SM00342 175 257 1.3E-19 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_23620 06bc57d095155d7e1019b40eee166733 261 SUPERFAMILY SSF51182 3 183 1.07E-13 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_23620 06bc57d095155d7e1019b40eee166733 261 Gene3D G3DSA:2.60.120.10 3 97 8.9E-7 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_23620 06bc57d095155d7e1019b40eee166733 261 Gene3D G3DSA:1.10.10.60 157 261 2.8E-19 T 14-10-2018 LH59_23620 06bc57d095155d7e1019b40eee166733 261 SUPERFAMILY SSF46689 214 256 6.81E-7 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_06150 b215fccccd8568abd5ccd2bc937f0947 216 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 19 162 5.7E-32 T 14-10-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06150 b215fccccd8568abd5ccd2bc937f0947 216 Gene3D G3DSA:1.20.120.1200 4 164 8.4E-40 T 14-10-2018 LH59_27970 cd8c6bc07fee2951207c3e9b533f8e47 1414 SUPERFAMILY SSF64484 16 1363 0.0 T 14-10-2018 LH59_27970 cd8c6bc07fee2951207c3e9b533f8e47 1414 Pfam PF04983 RNA polymerase Rpb1, domain 3 489 644 7.3E-25 T 14-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LH59_27970 cd8c6bc07fee2951207c3e9b533f8e47 1414 Pfam PF00623 RNA polymerase Rpb1, domain 2 344 395 3.7E-8 T 14-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LH59_27970 cd8c6bc07fee2951207c3e9b533f8e47 1414 Pfam PF00623 RNA polymerase Rpb1, domain 2 395 485 1.8E-26 T 14-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LH59_27970 cd8c6bc07fee2951207c3e9b533f8e47 1414 SMART SM00663 235 514 1.7E-172 T 14-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LH59_27970 cd8c6bc07fee2951207c3e9b533f8e47 1414 Pfam PF04998 RNA polymerase Rpb1, domain 5 766 1315 8.3E-77 T 14-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LH59_27970 cd8c6bc07fee2951207c3e9b533f8e47 1414 Gene3D G3DSA:2.40.50.100 1151 1214 9.9E-68 T 14-10-2018 LH59_27970 cd8c6bc07fee2951207c3e9b533f8e47 1414 Gene3D G3DSA:1.10.40.90 374 416 3.7E-20 T 14-10-2018 LH59_27970 cd8c6bc07fee2951207c3e9b533f8e47 1414 Pfam PF05000 RNA polymerase Rpb1, domain 4 674 763 7.6E-18 T 14-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LH59_27970 cd8c6bc07fee2951207c3e9b533f8e47 1414 Gene3D G3DSA:1.10.132.30 641 790 6.6E-64 T 14-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LH59_27970 cd8c6bc07fee2951207c3e9b533f8e47 1414 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 11 1376 18.794 T 14-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LH59_27970 cd8c6bc07fee2951207c3e9b533f8e47 1414 Gene3D G3DSA:1.10.150.390 1315 1376 3.7E-28 T 14-10-2018 LH59_27970 cd8c6bc07fee2951207c3e9b533f8e47 1414 Gene3D G3DSA:2.40.50.100 948 1023 1.6E-26 T 14-10-2018 LH59_27970 cd8c6bc07fee2951207c3e9b533f8e47 1414 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 19 1365 0.0 T 14-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LH59_27970 cd8c6bc07fee2951207c3e9b533f8e47 1414 Gene3D G3DSA:1.10.274.100 490 640 4.9E-36 T 14-10-2018 LH59_27970 cd8c6bc07fee2951207c3e9b533f8e47 1414 Gene3D G3DSA:1.10.1790.20 1135 1313 9.9E-68 T 14-10-2018 LH59_27970 cd8c6bc07fee2951207c3e9b533f8e47 1414 Gene3D G3DSA:2.40.50.100 1024 1126 8.7E-29 T 14-10-2018 LH59_27970 cd8c6bc07fee2951207c3e9b533f8e47 1414 Pfam PF04997 RNA polymerase Rpb1, domain 1 15 342 3.9E-85 T 14-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 LH59_13615 1f8f4f3359da3bf53cf1a07fcc7ab293 311 Gene3D G3DSA:3.40.50.300 1 311 7.0E-102 T 14-10-2018 LH59_13615 1f8f4f3359da3bf53cf1a07fcc7ab293 311 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_13615 1f8f4f3359da3bf53cf1a07fcc7ab293 311 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 224 289 5.9E-19 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_13615 1f8f4f3359da3bf53cf1a07fcc7ab293 311 SMART SM00382 31 222 8.3E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_13615 1f8f4f3359da3bf53cf1a07fcc7ab293 311 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 222 309 5.9E-27 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_13615 1f8f4f3359da3bf53cf1a07fcc7ab293 311 Pfam PF00005 ABC transporter 23 172 1.6E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_13615 1f8f4f3359da3bf53cf1a07fcc7ab293 311 SUPERFAMILY SSF52540 1 244 6.66E-77 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_03160 f03b4e5b48ee71459bcb99321b3a277e 456 Pfam PF01225 Mur ligase family, catalytic domain 2 97 3.8E-16 T 14-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 LH59_03160 f03b4e5b48ee71459bcb99321b3a277e 456 SUPERFAMILY SSF53244 310 452 3.14E-36 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 LH59_03160 f03b4e5b48ee71459bcb99321b3a277e 456 TIGRFAM TIGR01081 mpl: UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase 2 452 1.7E-201 T 14-10-2018 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 MetaCyc: PWY-7883 LH59_03160 f03b4e5b48ee71459bcb99321b3a277e 456 Gene3D G3DSA:3.90.190.20 314 454 1.3E-27 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 LH59_03160 f03b4e5b48ee71459bcb99321b3a277e 456 Gene3D G3DSA:3.40.1190.10 91 313 5.5E-56 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 LH59_03160 f03b4e5b48ee71459bcb99321b3a277e 456 SUPERFAMILY SSF53623 98 308 5.1E-47 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 LH59_03160 f03b4e5b48ee71459bcb99321b3a277e 456 Pfam PF08245 Mur ligase middle domain 108 291 1.4E-19 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 LH59_03160 f03b4e5b48ee71459bcb99321b3a277e 456 Gene3D G3DSA:3.40.50.720 1 90 1.7E-34 T 14-10-2018 LH59_03160 f03b4e5b48ee71459bcb99321b3a277e 456 SUPERFAMILY SSF51984 1 89 6.02E-19 T 14-10-2018 LH59_03160 f03b4e5b48ee71459bcb99321b3a277e 456 Pfam PF02875 Mur ligase family, glutamate ligase domain 311 390 2.3E-10 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 LH59_03160 f03b4e5b48ee71459bcb99321b3a277e 456 Hamap MF_02020 UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptandioate ligase [mpl]. 1 453 57.218 T 14-10-2018 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 MetaCyc: PWY-7883 LH59_16865 8b2129acd69c088bcf71b99052c72503 382 Pfam PF03781 Sulfatase-modifying factor enzyme 1 50 363 6.6E-83 T 14-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 LH59_16865 8b2129acd69c088bcf71b99052c72503 382 Gene3D G3DSA:3.90.1580.10 35 377 6.3E-104 T 14-10-2018 LH59_16865 8b2129acd69c088bcf71b99052c72503 382 SUPERFAMILY SSF56436 48 366 3.01E-84 T 14-10-2018 IPR016187 C-type lectin fold LH59_06405 38583221a63e1d566c94165547459d44 763 Gene3D G3DSA:1.10.3210.10 16 214 2.2E-42 T 14-10-2018 LH59_06405 38583221a63e1d566c94165547459d44 763 SUPERFAMILY SSF109604 17 213 1.07E-41 T 14-10-2018 LH59_06405 38583221a63e1d566c94165547459d44 763 Pfam PF13291 ACT domain 688 762 2.5E-15 T 14-10-2018 IPR002912 ACT domain LH59_06405 38583221a63e1d566c94165547459d44 763 Pfam PF04607 Region found in RelA / SpoT proteins 258 367 1.8E-37 T 14-10-2018 IPR007685 RelA/SpoT GO:0015969 LH59_06405 38583221a63e1d566c94165547459d44 763 Gene3D G3DSA:3.30.460.10 216 348 4.5E-50 T 14-10-2018 LH59_06405 38583221a63e1d566c94165547459d44 763 SMART SM00954 258 368 9.9E-64 T 14-10-2018 IPR007685 RelA/SpoT GO:0015969 LH59_06405 38583221a63e1d566c94165547459d44 763 SUPERFAMILY SSF55021 687 761 9.87E-14 T 14-10-2018 LH59_06405 38583221a63e1d566c94165547459d44 763 SUPERFAMILY SSF81301 215 393 1.5E-62 T 14-10-2018 LH59_06405 38583221a63e1d566c94165547459d44 763 Pfam PF13328 HD domain 36 199 1.8E-48 T 14-10-2018 IPR003607 HD/PDEase domain LH59_06405 38583221a63e1d566c94165547459d44 763 Gene3D G3DSA:3.30.70.260 687 763 8.6E-18 T 14-10-2018 LH59_06405 38583221a63e1d566c94165547459d44 763 Gene3D G3DSA:3.10.20.30 433 501 6.1E-28 T 14-10-2018 IPR012675 Beta-grasp domain superfamily LH59_06405 38583221a63e1d566c94165547459d44 763 Pfam PF02824 TGS domain 437 495 1.0E-20 T 14-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 LH59_06405 38583221a63e1d566c94165547459d44 763 SUPERFAMILY SSF81271 435 496 1.63E-18 T 14-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 LH59_25175 690d8cb2e0ddc19b464dfaf8b960cae3 511 Pfam PF14698 Argininosuccinate lyase C-terminal 372 448 7.3E-12 T 14-10-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 LH59_25175 690d8cb2e0ddc19b464dfaf8b960cae3 511 Gene3D G3DSA:1.20.200.10 110 462 1.0E-82 T 14-10-2018 LH59_25175 690d8cb2e0ddc19b464dfaf8b960cae3 511 SUPERFAMILY SSF48557 33 473 3.77E-72 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 LH59_25175 690d8cb2e0ddc19b464dfaf8b960cae3 511 PRINTS PR00145 Argininosuccinate lyase family signature 144 164 1.1E-14 T 14-10-2018 LH59_25175 690d8cb2e0ddc19b464dfaf8b960cae3 511 PRINTS PR00145 Argininosuccinate lyase family signature 195 211 1.1E-14 T 14-10-2018 LH59_25175 690d8cb2e0ddc19b464dfaf8b960cae3 511 PRINTS PR00145 Argininosuccinate lyase family signature 281 297 1.1E-14 T 14-10-2018 LH59_25175 690d8cb2e0ddc19b464dfaf8b960cae3 511 PRINTS PR00145 Argininosuccinate lyase family signature 103 125 1.1E-14 T 14-10-2018 LH59_25175 690d8cb2e0ddc19b464dfaf8b960cae3 511 Gene3D G3DSA:1.10.40.30 366 450 1.0E-82 T 14-10-2018 LH59_25175 690d8cb2e0ddc19b464dfaf8b960cae3 511 PRINTS PR00149 Fumarate lyase superfamily signature 281 297 4.2E-7 T 14-10-2018 IPR000362 Fumarate lyase family LH59_25175 690d8cb2e0ddc19b464dfaf8b960cae3 511 PRINTS PR00149 Fumarate lyase superfamily signature 104 122 4.2E-7 T 14-10-2018 IPR000362 Fumarate lyase family LH59_25175 690d8cb2e0ddc19b464dfaf8b960cae3 511 PRINTS PR00149 Fumarate lyase superfamily signature 235 262 4.2E-7 T 14-10-2018 IPR000362 Fumarate lyase family LH59_25175 690d8cb2e0ddc19b464dfaf8b960cae3 511 PRINTS PR00149 Fumarate lyase superfamily signature 149 167 4.2E-7 T 14-10-2018 IPR000362 Fumarate lyase family LH59_25175 690d8cb2e0ddc19b464dfaf8b960cae3 511 Pfam PF00206 Lyase 103 295 1.1E-25 T 14-10-2018 IPR022761 Fumarate lyase, N-terminal LH59_21545 79c2e7cf2ac61dfc7e2e077baebcb598 467 Pfam PF01425 Amidase 28 446 5.9E-78 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_21545 79c2e7cf2ac61dfc7e2e077baebcb598 467 ProSitePatterns PS00571 Amidases signature. 153 184 - T 14-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 LH59_21545 79c2e7cf2ac61dfc7e2e077baebcb598 467 SUPERFAMILY SSF75304 3 454 1.96E-109 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_21545 79c2e7cf2ac61dfc7e2e077baebcb598 467 Gene3D G3DSA:3.90.1300.10 2 462 1.5E-108 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_19705 3eb6a16df009277bcb4ebbb9ff38bf97 336 Pfam PF00691 OmpA family 226 322 1.3E-20 T 14-10-2018 IPR006665 OmpA-like domain LH59_19705 3eb6a16df009277bcb4ebbb9ff38bf97 336 Pfam PF16234 Domain of unknown function (DUF4892) 36 129 1.0E-8 T 14-10-2018 IPR032608 Protein of unknown function DUF4892 LH59_19705 3eb6a16df009277bcb4ebbb9ff38bf97 336 Gene3D G3DSA:3.30.1330.60 190 332 4.2E-34 T 14-10-2018 IPR036737 OmpA-like domain superfamily LH59_19705 3eb6a16df009277bcb4ebbb9ff38bf97 336 PRINTS PR01021 OMPA domain signature 257 272 8.7E-13 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 LH59_19705 3eb6a16df009277bcb4ebbb9ff38bf97 336 PRINTS PR01021 OMPA domain signature 272 288 8.7E-13 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 LH59_19705 3eb6a16df009277bcb4ebbb9ff38bf97 336 PRINTS PR01021 OMPA domain signature 227 249 8.7E-13 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 LH59_19705 3eb6a16df009277bcb4ebbb9ff38bf97 336 SUPERFAMILY SSF103088 222 327 1.03E-31 T 14-10-2018 IPR036737 OmpA-like domain superfamily LH59_09975 040a80f89249408a1bbb0cd3b04291e2 151 Gene3D G3DSA:3.10.129.10 1 139 2.8E-17 T 14-10-2018 LH59_09975 040a80f89249408a1bbb0cd3b04291e2 151 SUPERFAMILY SSF54637 5 140 1.92E-23 T 14-10-2018 IPR029069 HotDog domain superfamily LH59_09975 040a80f89249408a1bbb0cd3b04291e2 151 PIRSF PIRSF020565 1 149 5.3E-51 T 14-10-2018 IPR016776 3-hydroxylacyl-(acyl carrier protein) dehydratase, predicted LH59_23625 4c5011dd63bc8b1e7105ae86f602e1ba 255 SUPERFAMILY SSF53335 5 203 5.63E-34 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_23625 4c5011dd63bc8b1e7105ae86f602e1ba 255 Gene3D G3DSA:3.40.50.150 8 251 1.1E-90 T 14-10-2018 LH59_23625 4c5011dd63bc8b1e7105ae86f602e1ba 255 Gene3D G3DSA:1.10.150.290 131 234 1.1E-90 T 14-10-2018 IPR023149 Trans-aconitate 2-methyltransferase, C-terminal GO:0030798 LH59_23625 4c5011dd63bc8b1e7105ae86f602e1ba 255 Hamap MF_00560 Trans-aconitate 2-methyltransferase [tam]. 1 254 41.607 T 14-10-2018 IPR023506 Trans-aconitate 2-methyltransferase GO:0030798 LH59_23625 4c5011dd63bc8b1e7105ae86f602e1ba 255 Pfam PF13489 Methyltransferase domain 12 142 3.8E-16 T 14-10-2018 LH59_15670 c25a4375e35e21bc39f0fd8ca8854c3e 228 SMART SM00895 82 205 8.2E-20 T 14-10-2018 IPR011711 GntR, C-terminal LH59_15670 c25a4375e35e21bc39f0fd8ca8854c3e 228 Pfam PF07729 FCD domain 82 204 6.0E-25 T 14-10-2018 IPR011711 GntR, C-terminal LH59_15670 c25a4375e35e21bc39f0fd8ca8854c3e 228 Gene3D G3DSA:1.20.120.530 77 211 3.4E-26 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_15670 c25a4375e35e21bc39f0fd8ca8854c3e 228 SUPERFAMILY SSF48008 78 209 2.38E-27 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_15670 c25a4375e35e21bc39f0fd8ca8854c3e 228 SMART SM00345 14 72 3.5E-11 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_15670 c25a4375e35e21bc39f0fd8ca8854c3e 228 SUPERFAMILY SSF46785 1 76 1.42E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_15670 c25a4375e35e21bc39f0fd8ca8854c3e 228 Gene3D G3DSA:1.10.10.10 2 73 7.5E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_15670 c25a4375e35e21bc39f0fd8ca8854c3e 228 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 72 5.5E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_08845 1a6b3e18e0f7218b7c8616a8eec7eead 203 SUPERFAMILY SSF52972 7 196 2.55E-57 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like LH59_08845 1a6b3e18e0f7218b7c8616a8eec7eead 203 Hamap MF_00528 Septum formation protein Maf [maf]. 8 202 30.081 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 LH59_08845 1a6b3e18e0f7218b7c8616a8eec7eead 203 Pfam PF02545 Maf-like protein 8 197 8.6E-53 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 LH59_08845 1a6b3e18e0f7218b7c8616a8eec7eead 203 TIGRFAM TIGR00172 maf: septum formation protein Maf 7 196 1.5E-44 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 LH59_08845 1a6b3e18e0f7218b7c8616a8eec7eead 203 Gene3D G3DSA:3.90.950.10 4 202 2.0E-67 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like LH59_08845 1a6b3e18e0f7218b7c8616a8eec7eead 203 PIRSF PIRSF006305 3 202 4.9E-47 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 LH59_09615 e9eaf8c62aec2b3c58613a105f3f84a5 166 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 1 155 9.6E-66 T 14-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 LH59_09615 e9eaf8c62aec2b3c58613a105f3f84a5 166 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 1 61 1.0E-24 T 14-10-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 LH59_09615 e9eaf8c62aec2b3c58613a105f3f84a5 166 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 68 153 1.9E-39 T 14-10-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 LH59_09615 e9eaf8c62aec2b3c58613a105f3f84a5 166 SUPERFAMILY SSF54364 1 62 5.62E-24 T 14-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 LH59_09615 e9eaf8c62aec2b3c58613a105f3f84a5 166 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 1 155 27.36 T 14-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 LH59_09615 e9eaf8c62aec2b3c58613a105f3f84a5 166 Gene3D G3DSA:3.30.110.10 61 156 6.0E-38 T 14-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 LH59_09615 e9eaf8c62aec2b3c58613a105f3f84a5 166 Gene3D G3DSA:3.10.20.80 1 60 1.8E-24 T 14-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 LH59_09615 e9eaf8c62aec2b3c58613a105f3f84a5 166 ProSitePatterns PS00938 Initiation factor 3 signature. 43 56 - T 14-10-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 LH59_09615 e9eaf8c62aec2b3c58613a105f3f84a5 166 SUPERFAMILY SSF55200 67 155 1.29E-34 T 14-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 LH59_22155 c5ed483d6e360e134ef2753966506ec0 427 SUPERFAMILY SSF56601 156 412 1.88E-59 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like LH59_22155 c5ed483d6e360e134ef2753966506ec0 427 Gene3D G3DSA:3.40.710.10 145 424 3.2E-67 T 14-10-2018 LH59_22155 c5ed483d6e360e134ef2753966506ec0 427 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 173 398 3.8E-55 T 14-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 LH59_22155 c5ed483d6e360e134ef2753966506ec0 427 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 205 216 1.0E-11 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 LH59_22155 c5ed483d6e360e134ef2753966506ec0 427 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 255 272 1.0E-11 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 LH59_22155 c5ed483d6e360e134ef2753966506ec0 427 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 282 295 1.0E-11 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 LH59_19150 61fe662f9408e0016c8a902923659c6e 676 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 39 243 2.6E-34 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit LH59_19150 61fe662f9408e0016c8a902923659c6e 676 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 467 665 1.9E-38 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit LH59_19150 61fe662f9408e0016c8a902923659c6e 676 PRINTS PR00173 Glutamate-aspartate symporter signature 204 226 3.5E-5 T 14-10-2018 LH59_19150 61fe662f9408e0016c8a902923659c6e 676 PRINTS PR00173 Glutamate-aspartate symporter signature 390 409 3.5E-5 T 14-10-2018 LH59_19150 61fe662f9408e0016c8a902923659c6e 676 PRINTS PR00173 Glutamate-aspartate symporter signature 35 55 3.5E-5 T 14-10-2018 LH59_19150 61fe662f9408e0016c8a902923659c6e 676 PRINTS PR00173 Glutamate-aspartate symporter signature 133 158 3.5E-5 T 14-10-2018 LH59_23570 49cd5b367a0399e66a5d653e1754593d 167 Gene3D G3DSA:1.10.1740.10 3 75 3.4E-5 T 14-10-2018 LH59_23570 49cd5b367a0399e66a5d653e1754593d 167 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 14 162 4.2E-23 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 LH59_23570 49cd5b367a0399e66a5d653e1754593d 167 Pfam PF04542 Sigma-70 region 2 15 75 2.8E-6 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 LH59_23570 49cd5b367a0399e66a5d653e1754593d 167 SUPERFAMILY SSF88659 91 165 8.78E-15 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like LH59_23570 49cd5b367a0399e66a5d653e1754593d 167 SUPERFAMILY SSF88946 13 91 3.37E-10 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 LH59_23570 49cd5b367a0399e66a5d653e1754593d 167 Pfam PF08281 Sigma-70, region 4 107 157 1.5E-12 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LH59_23570 49cd5b367a0399e66a5d653e1754593d 167 Gene3D G3DSA:1.10.10.10 76 166 7.5E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_20015 25f4c39fbd11350045cfdee9a4f505f7 186 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 128 159 2.1E-4 T 14-10-2018 IPR001451 Hexapeptide repeat LH59_20015 25f4c39fbd11350045cfdee9a4f505f7 186 Gene3D G3DSA:2.160.10.10 30 183 3.3E-28 T 14-10-2018 LH59_20015 25f4c39fbd11350045cfdee9a4f505f7 186 SUPERFAMILY SSF51161 25 181 1.07E-34 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily LH59_20015 25f4c39fbd11350045cfdee9a4f505f7 186 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 136 164 - T 14-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 LH59_13660 1bcc4513f093db865277b3d269cc27af 244 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 66 1.2E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_13660 1bcc4513f093db865277b3d269cc27af 244 Gene3D G3DSA:1.10.10.10 5 67 3.7E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_13660 1bcc4513f093db865277b3d269cc27af 244 Gene3D G3DSA:1.20.120.530 69 222 1.2E-26 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_13660 1bcc4513f093db865277b3d269cc27af 244 SMART SM00345 8 66 5.4E-12 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_13660 1bcc4513f093db865277b3d269cc27af 244 SUPERFAMILY SSF48008 72 220 8.63E-21 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_13660 1bcc4513f093db865277b3d269cc27af 244 SMART SM00895 76 216 1.2E-20 T 14-10-2018 IPR011711 GntR, C-terminal LH59_13660 1bcc4513f093db865277b3d269cc27af 244 Pfam PF07729 FCD domain 77 213 1.9E-20 T 14-10-2018 IPR011711 GntR, C-terminal LH59_13660 1bcc4513f093db865277b3d269cc27af 244 SUPERFAMILY SSF46785 6 95 1.97E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_11025 2d55d5502ceb5913b9e3063db96b39c6 688 PIRSF PIRSF006630 11 675 1.3E-157 T 14-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 LH59_11025 2d55d5502ceb5913b9e3063db96b39c6 688 Pfam PF02540 NAD synthase 351 526 1.6E-25 T 14-10-2018 IPR022310 NAD/GMP synthase LH59_11025 2d55d5502ceb5913b9e3063db96b39c6 688 SUPERFAMILY SSF56317 13 297 2.62E-49 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily LH59_11025 2d55d5502ceb5913b9e3063db96b39c6 688 Gene3D G3DSA:1.10.10.1140 564 684 2.9E-46 T 14-10-2018 LH59_11025 2d55d5502ceb5913b9e3063db96b39c6 688 Pfam PF00795 Carbon-nitrogen hydrolase 17 282 2.9E-19 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 LH59_11025 2d55d5502ceb5913b9e3063db96b39c6 688 SUPERFAMILY SSF52402 330 653 1.06E-63 T 14-10-2018 LH59_11025 2d55d5502ceb5913b9e3063db96b39c6 688 Gene3D G3DSA:3.60.110.10 3 325 2.3E-86 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily LH59_11025 2d55d5502ceb5913b9e3063db96b39c6 688 TIGRFAM TIGR00552 nadE: NAD+ synthetase 355 525 3.4E-20 T 14-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 LH59_11025 2d55d5502ceb5913b9e3063db96b39c6 688 Gene3D G3DSA:3.40.50.620 328 548 1.0E-62 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LH59_11025 2d55d5502ceb5913b9e3063db96b39c6 688 Hamap MF_02090 Glutamine-dependent NAD(+) synthetase [nadE]. 14 673 28.287 T 14-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 LH59_20650 eb4d7511759c692908a319d59000fb2d 426 SUPERFAMILY SSF103473 13 404 1.18E-32 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_20650 eb4d7511759c692908a319d59000fb2d 426 Pfam PF07690 Major Facilitator Superfamily 17 367 6.9E-17 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_20650 eb4d7511759c692908a319d59000fb2d 426 Gene3D G3DSA:1.20.1250.20 10 403 9.0E-24 T 14-10-2018 LH59_01670 d851a829ea78ff6f69f4be031ee2fc23 301 SUPERFAMILY SSF52540 38 256 2.77E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_01670 d851a829ea78ff6f69f4be031ee2fc23 301 Pfam PF00005 ABC transporter 53 194 7.4E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_01670 d851a829ea78ff6f69f4be031ee2fc23 301 ProSitePatterns PS00211 ABC transporters family signature. 167 181 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_01670 d851a829ea78ff6f69f4be031ee2fc23 301 Gene3D G3DSA:3.40.50.300 37 290 2.5E-64 T 14-10-2018 LH59_01670 d851a829ea78ff6f69f4be031ee2fc23 301 SMART SM00382 62 257 1.3E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_26110 5e206d69142275211ce72608891f28cf 265 SUPERFAMILY SSF53850 28 265 2.17E-80 T 14-10-2018 LH59_26110 5e206d69142275211ce72608891f28cf 265 Pfam PF03180 NLPA lipoprotein 29 264 1.6E-87 T 14-10-2018 IPR004872 Lipoprotein NlpA family LH59_26110 5e206d69142275211ce72608891f28cf 265 TIGRFAM TIGR00363 TIGR00363: lipoprotein, YaeC family 25 263 2.6E-76 T 14-10-2018 IPR004872 Lipoprotein NlpA family LH59_26110 5e206d69142275211ce72608891f28cf 265 Gene3D G3DSA:3.40.190.10 29 260 9.9E-92 T 14-10-2018 LH59_26110 5e206d69142275211ce72608891f28cf 265 PIRSF PIRSF002854 2 265 3.1E-94 T 14-10-2018 IPR004872 Lipoprotein NlpA family LH59_26110 5e206d69142275211ce72608891f28cf 265 Gene3D G3DSA:3.40.190.10 110 214 9.9E-92 T 14-10-2018 LH59_22240 b13a27e4c5a6d0340f061148519c6e34 156 Pfam PF16155 Domain of unknown function (DUF4863) 11 153 1.2E-56 T 14-10-2018 IPR032345 Protein of unknown function DUF4863 LH59_07725 d4bc521c6bccad064ccc9ba092969ead 283 Gene3D G3DSA:3.40.250.10 2 148 1.8E-48 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily LH59_07725 d4bc521c6bccad064ccc9ba092969ead 283 SMART SM00450 157 277 6.9E-9 T 14-10-2018 IPR001763 Rhodanese-like domain LH59_07725 d4bc521c6bccad064ccc9ba092969ead 283 SMART SM00450 6 132 1.2E-23 T 14-10-2018 IPR001763 Rhodanese-like domain LH59_07725 d4bc521c6bccad064ccc9ba092969ead 283 ProSitePatterns PS00380 Rhodanese signature 1. 39 50 - T 14-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 LH59_07725 d4bc521c6bccad064ccc9ba092969ead 283 SUPERFAMILY SSF52821 2 149 6.55E-44 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily LH59_07725 d4bc521c6bccad064ccc9ba092969ead 283 SUPERFAMILY SSF52821 160 282 1.19E-31 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily LH59_07725 d4bc521c6bccad064ccc9ba092969ead 283 Gene3D G3DSA:3.40.250.10 160 282 3.1E-31 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily LH59_07725 d4bc521c6bccad064ccc9ba092969ead 283 Pfam PF00581 Rhodanese-like domain 8 129 3.5E-18 T 14-10-2018 IPR001763 Rhodanese-like domain LH59_07725 d4bc521c6bccad064ccc9ba092969ead 283 Pfam PF00581 Rhodanese-like domain 159 273 4.4E-7 T 14-10-2018 IPR001763 Rhodanese-like domain LH59_12390 c350e5ca082a02e609ca55c38b411278 389 Gene3D G3DSA:1.20.1250.20 2 377 1.6E-36 T 14-10-2018 LH59_12390 c350e5ca082a02e609ca55c38b411278 389 SUPERFAMILY SSF103473 4 380 4.45E-43 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_12390 c350e5ca082a02e609ca55c38b411278 389 Pfam PF07690 Major Facilitator Superfamily 9 310 3.7E-26 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_06660 ea09fac1a4367ec69f130ae7d01af884 135 Gene3D G3DSA:3.30.450.150 1 134 3.7E-37 T 14-10-2018 IPR038084 GlcG-like domain superfamily LH59_06660 ea09fac1a4367ec69f130ae7d01af884 135 SUPERFAMILY SSF143744 2 134 2.35E-37 T 14-10-2018 IPR038084 GlcG-like domain superfamily LH59_06660 ea09fac1a4367ec69f130ae7d01af884 135 Pfam PF03928 Haem-degrading 7 130 5.6E-31 T 14-10-2018 IPR005624 Haem-degrading LH59_21205 b89f20732d67eee4115658173483be2f 246 Pfam PF03740 Pyridoxal phosphate biosynthesis protein PdxJ 3 235 1.4E-98 T 14-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 LH59_21205 b89f20732d67eee4115658173483be2f 246 SUPERFAMILY SSF63892 1 238 1.01E-94 T 14-10-2018 IPR036130 Pyridoxine 5'-phosphate synthase GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 LH59_21205 b89f20732d67eee4115658173483be2f 246 Gene3D G3DSA:3.20.20.70 1 246 7.2E-103 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_21205 b89f20732d67eee4115658173483be2f 246 Hamap MF_00279 Pyridoxine 5'-phosphate synthase [pdxJ]. 1 240 125.97 T 14-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 LH59_21205 b89f20732d67eee4115658173483be2f 246 TIGRFAM TIGR00559 pdxJ: pyridoxine 5'-phosphate synthase 4 236 4.1E-88 T 14-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 LH59_00085 1ffa289279ebce1351456846622f1662 301 Pfam PF00892 EamA-like transporter family 11 135 1.0E-18 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_00085 1ffa289279ebce1351456846622f1662 301 Pfam PF00892 EamA-like transporter family 149 290 3.8E-17 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_00085 1ffa289279ebce1351456846622f1662 301 SUPERFAMILY SSF103481 44 139 4.45E-13 T 14-10-2018 LH59_00085 1ffa289279ebce1351456846622f1662 301 SUPERFAMILY SSF103481 216 296 4.58E-10 T 14-10-2018 LH59_18020 c1ab65bc5e695bafbf438820f9c8d659 237 Pfam PF07729 FCD domain 102 224 1.5E-25 T 14-10-2018 IPR011711 GntR, C-terminal LH59_18020 c1ab65bc5e695bafbf438820f9c8d659 237 Gene3D G3DSA:1.10.10.10 10 80 4.0E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_18020 c1ab65bc5e695bafbf438820f9c8d659 237 SMART SM00345 18 77 2.8E-23 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_18020 c1ab65bc5e695bafbf438820f9c8d659 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 1.2E-10 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_18020 c1ab65bc5e695bafbf438820f9c8d659 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 1.2E-10 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_18020 c1ab65bc5e695bafbf438820f9c8d659 237 Gene3D G3DSA:1.20.120.530 100 235 5.1E-29 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_18020 c1ab65bc5e695bafbf438820f9c8d659 237 SUPERFAMILY SSF46785 8 81 3.05E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_18020 c1ab65bc5e695bafbf438820f9c8d659 237 SMART SM00895 99 226 2.3E-20 T 14-10-2018 IPR011711 GntR, C-terminal LH59_18020 c1ab65bc5e695bafbf438820f9c8d659 237 SUPERFAMILY SSF48008 101 233 1.26E-26 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_18020 c1ab65bc5e695bafbf438820f9c8d659 237 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 77 7.0E-22 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_26095 84048fc3cef9977ee0abb3632e0adf14 262 Gene3D G3DSA:1.10.230.10 101 203 1.1E-24 T 14-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain LH59_26095 84048fc3cef9977ee0abb3632e0adf14 262 Gene3D G3DSA:1.10.580.10 31 229 1.1E-24 T 14-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 LH59_26095 84048fc3cef9977ee0abb3632e0adf14 262 Pfam PF00285 Citrate synthase, C-terminal domain 34 231 1.3E-24 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 LH59_26095 84048fc3cef9977ee0abb3632e0adf14 262 SUPERFAMILY SSF48256 30 238 3.01E-39 T 14-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 LH59_12705 0108979cbb698ba3d5ad066abe84a9fa 244 Hamap MF_00564 Ribonuclease PH [rph]. 18 244 45.007 T 14-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 LH59_12705 0108979cbb698ba3d5ad066abe84a9fa 244 SUPERFAMILY SSF54211 9 188 5.57E-45 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold LH59_12705 0108979cbb698ba3d5ad066abe84a9fa 244 ProSitePatterns PS01277 Ribonuclease PH signature. 123 135 - T 14-10-2018 IPR018336 Ribonuclease PH, conserved site LH59_12705 0108979cbb698ba3d5ad066abe84a9fa 244 SUPERFAMILY SSF55666 160 243 6.54E-24 T 14-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 LH59_12705 0108979cbb698ba3d5ad066abe84a9fa 244 Pfam PF01138 3' exoribonuclease family, domain 1 17 147 1.4E-19 T 14-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 LH59_12705 0108979cbb698ba3d5ad066abe84a9fa 244 Pfam PF03725 3' exoribonuclease family, domain 2 165 230 4.1E-12 T 14-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 LH59_12705 0108979cbb698ba3d5ad066abe84a9fa 244 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 9 243 4.1E-114 T 14-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 LH59_12705 0108979cbb698ba3d5ad066abe84a9fa 244 Gene3D G3DSA:3.30.230.70 16 244 1.5E-59 T 14-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 LH59_21200 92abc61cec816f034eb4dfe39f09a6e1 145 SUPERFAMILY SSF56214 16 142 2.09E-26 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 LH59_21200 92abc61cec816f034eb4dfe39f09a6e1 145 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 17 143 24.642 T 14-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 LH59_21200 92abc61cec816f034eb4dfe39f09a6e1 145 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 22 126 5.0E-48 T 14-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 LH59_21200 92abc61cec816f034eb4dfe39f09a6e1 145 Gene3D G3DSA:3.90.470.20 13 144 6.1E-31 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 LH59_21200 92abc61cec816f034eb4dfe39f09a6e1 145 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 16 143 2.9E-19 T 14-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 LH59_21200 92abc61cec816f034eb4dfe39f09a6e1 145 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 16 143 2.1E-27 T 14-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 LH59_21200 92abc61cec816f034eb4dfe39f09a6e1 145 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 18 121 7.8E-19 T 14-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 LH59_05980 fb234e1a1016ed0efd0b781a5400a3cf 520 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 69 423 5.6E-91 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain LH59_05980 fb234e1a1016ed0efd0b781a5400a3cf 520 Gene3D G3DSA:3.90.76.10 42 191 4.7E-120 T 14-10-2018 LH59_05980 fb234e1a1016ed0efd0b781a5400a3cf 520 Gene3D G3DSA:3.10.105.10 284 494 4.7E-120 T 14-10-2018 LH59_05980 fb234e1a1016ed0efd0b781a5400a3cf 520 Gene3D G3DSA:3.40.190.10 192 504 4.7E-120 T 14-10-2018 LH59_05980 fb234e1a1016ed0efd0b781a5400a3cf 520 PIRSF PIRSF002741 3 518 1.1E-95 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 LH59_05980 fb234e1a1016ed0efd0b781a5400a3cf 520 SUPERFAMILY SSF53850 24 507 2.41E-120 T 14-10-2018 LH59_24605 f83ec2a7ce9e1d6d339321119b4f196b 304 SUPERFAMILY SSF69593 59 291 6.93E-29 T 14-10-2018 LH59_24605 f83ec2a7ce9e1d6d339321119b4f196b 304 Pfam PF01553 Acyltransferase 87 230 1.3E-13 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 LH59_24605 f83ec2a7ce9e1d6d339321119b4f196b 304 SMART SM00563 89 231 1.3E-17 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 LH59_09535 d271259fb030a64f59dd95b0a032cb36 352 Gene3D G3DSA:3.40.800.20 1 352 2.9E-108 T 14-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 LH59_09535 d271259fb030a64f59dd95b0a032cb36 352 Pfam PF00850 Histone deacetylase domain 48 347 2.6E-64 T 14-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 LH59_09535 d271259fb030a64f59dd95b0a032cb36 352 PRINTS PR01270 Histone deacetylase superfamily signature 166 189 1.1E-14 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 LH59_09535 d271259fb030a64f59dd95b0a032cb36 352 PRINTS PR01270 Histone deacetylase superfamily signature 284 294 1.1E-14 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 LH59_09535 d271259fb030a64f59dd95b0a032cb36 352 PRINTS PR01270 Histone deacetylase superfamily signature 198 213 1.1E-14 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 LH59_09535 d271259fb030a64f59dd95b0a032cb36 352 SUPERFAMILY SSF52768 4 350 2.69E-83 T 14-10-2018 IPR023696 Ureohydrolase domain superfamily LH59_24450 ca3f64645b73b47e502d1af3e6726ffc 552 Gene3D G3DSA:1.40.20.10 405 548 1.9E-25 T 14-10-2018 IPR038186 CHAD domain superfamily LH59_24450 ca3f64645b73b47e502d1af3e6726ffc 552 Gene3D G3DSA:1.40.20.10 222 401 1.9E-19 T 14-10-2018 IPR038186 CHAD domain superfamily LH59_24450 ca3f64645b73b47e502d1af3e6726ffc 552 SMART SM01118 1 193 6.8E-26 T 14-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 LH59_24450 ca3f64645b73b47e502d1af3e6726ffc 552 Gene3D G3DSA:2.40.320.10 1 188 1.6E-23 T 14-10-2018 LH59_24450 ca3f64645b73b47e502d1af3e6726ffc 552 SMART SM00880 242 544 1.4E-53 T 14-10-2018 IPR007899 CHAD domain LH59_24450 ca3f64645b73b47e502d1af3e6726ffc 552 Pfam PF05235 CHAD domain 243 508 3.7E-42 T 14-10-2018 IPR007899 CHAD domain LH59_24450 ca3f64645b73b47e502d1af3e6726ffc 552 SUPERFAMILY SSF55154 1 191 4.74E-31 T 14-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 LH59_24450 ca3f64645b73b47e502d1af3e6726ffc 552 Pfam PF01928 CYTH domain 1 185 3.6E-18 T 14-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 LH59_07215 10332bbfa8ab3cbe270fb3d79c4bb2f1 912 Pfam PF13283 Bacteriophage N adsorption protein A C-term 794 906 1.7E-22 T 14-10-2018 IPR025137 Bacteriophage N4 adsorption protein A, C-terminal LH59_07215 10332bbfa8ab3cbe270fb3d79c4bb2f1 912 SUPERFAMILY SSF48452 228 329 8.63E-11 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_07215 10332bbfa8ab3cbe270fb3d79c4bb2f1 912 Gene3D G3DSA:1.25.40.10 143 332 1.3E-16 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_07215 10332bbfa8ab3cbe270fb3d79c4bb2f1 912 SUPERFAMILY SSF48452 40 205 1.99E-10 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_07215 10332bbfa8ab3cbe270fb3d79c4bb2f1 912 SMART SM00028 292 325 230.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 LH59_07215 10332bbfa8ab3cbe270fb3d79c4bb2f1 912 SMART SM00028 411 444 58.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 LH59_07215 10332bbfa8ab3cbe270fb3d79c4bb2f1 912 SMART SM00028 40 73 110.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 LH59_07215 10332bbfa8ab3cbe270fb3d79c4bb2f1 912 SMART SM00028 481 514 22.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 LH59_07215 10332bbfa8ab3cbe270fb3d79c4bb2f1 912 Gene3D G3DSA:1.25.40.10 402 560 8.8E-15 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_07215 10332bbfa8ab3cbe270fb3d79c4bb2f1 912 SUPERFAMILY SSF48452 417 544 3.16E-12 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_07215 10332bbfa8ab3cbe270fb3d79c4bb2f1 912 Gene3D G3DSA:1.25.40.10 36 119 3.9E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_00285 3d6f13b1aaa7a350e6fb23848061dd63 402 Hamap MF_02091 Uncharacterized MFS-type transporter YfcJ [yfcJ]. 24 401 35.3 T 14-10-2018 IPR037541 Uncharacterized MFS-type transporter YfcJ LH59_00285 3d6f13b1aaa7a350e6fb23848061dd63 402 Gene3D G3DSA:1.20.1250.20 22 399 4.0E-33 T 14-10-2018 LH59_00285 3d6f13b1aaa7a350e6fb23848061dd63 402 SUPERFAMILY SSF103473 24 397 2.09E-40 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_00285 3d6f13b1aaa7a350e6fb23848061dd63 402 Pfam PF07690 Major Facilitator Superfamily 230 395 2.7E-12 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_00285 3d6f13b1aaa7a350e6fb23848061dd63 402 Pfam PF07690 Major Facilitator Superfamily 27 204 1.4E-12 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_24650 004bd1c0fdce83d57a813f3f5148c5fc 442 SUPERFAMILY SSF47384 200 279 9.42E-12 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 LH59_24650 004bd1c0fdce83d57a813f3f5148c5fc 442 SMART SM00387 324 439 3.3E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_24650 004bd1c0fdce83d57a813f3f5148c5fc 442 Gene3D G3DSA:3.30.565.10 274 437 4.1E-24 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_24650 004bd1c0fdce83d57a813f3f5148c5fc 442 Gene3D G3DSA:1.10.287.130 167 269 1.7E-14 T 14-10-2018 LH59_24650 004bd1c0fdce83d57a813f3f5148c5fc 442 SMART SM00388 217 283 8.9E-6 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_24650 004bd1c0fdce83d57a813f3f5148c5fc 442 Pfam PF00512 His Kinase A (phospho-acceptor) domain 219 279 7.9E-7 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_24650 004bd1c0fdce83d57a813f3f5148c5fc 442 SUPERFAMILY SSF55874 273 435 5.89E-24 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_24650 004bd1c0fdce83d57a813f3f5148c5fc 442 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 328 435 3.8E-14 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_22135 387176432cafa4b95bc28beb3ecf0012 316 Gene3D G3DSA:3.20.20.70 2 305 4.1E-99 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_22135 387176432cafa4b95bc28beb3ecf0012 316 SUPERFAMILY SSF51569 4 303 1.61E-58 T 14-10-2018 LH59_22135 387176432cafa4b95bc28beb3ecf0012 316 Pfam PF00682 HMGL-like 6 285 4.9E-38 T 14-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 LH59_14750 fd027d9a50773ccf38467d7acbe10bb1 464 Gene3D G3DSA:3.40.640.10 141 358 4.0E-79 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_14750 fd027d9a50773ccf38467d7acbe10bb1 464 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 70 2.4E-15 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_14750 fd027d9a50773ccf38467d7acbe10bb1 464 SUPERFAMILY SSF53383 83 456 1.32E-82 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_14750 fd027d9a50773ccf38467d7acbe10bb1 464 Gene3D G3DSA:3.90.1150.10 111 452 4.0E-79 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_14750 fd027d9a50773ccf38467d7acbe10bb1 464 SMART SM00345 11 70 2.9E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_14750 fd027d9a50773ccf38467d7acbe10bb1 464 Pfam PF00155 Aminotransferase class I and II 128 456 8.8E-40 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LH59_14750 fd027d9a50773ccf38467d7acbe10bb1 464 SUPERFAMILY SSF46785 4 73 2.12E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_14750 fd027d9a50773ccf38467d7acbe10bb1 464 Gene3D G3DSA:1.10.10.10 7 104 2.7E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_00010 6bd0f0fa2f1a3867dbaeb6c110d31dc6 369 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 7 368 1.4E-91 T 14-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 LH59_00010 6bd0f0fa2f1a3867dbaeb6c110d31dc6 369 PIRSF PIRSF000804 1 369 2.5E-109 T 14-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 LH59_00010 6bd0f0fa2f1a3867dbaeb6c110d31dc6 369 Gene3D G3DSA:3.10.150.10 2 123 9.8E-34 T 14-10-2018 LH59_00010 6bd0f0fa2f1a3867dbaeb6c110d31dc6 369 SUPERFAMILY SSF55979 6 118 1.59E-21 T 14-10-2018 LH59_00010 6bd0f0fa2f1a3867dbaeb6c110d31dc6 369 Gene3D G3DSA:3.10.150.10 250 369 1.5E-35 T 14-10-2018 LH59_00010 6bd0f0fa2f1a3867dbaeb6c110d31dc6 369 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 248 368 1.4E-30 T 14-10-2018 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 LH59_00010 6bd0f0fa2f1a3867dbaeb6c110d31dc6 369 SUPERFAMILY SSF55979 127 246 4.85E-29 T 14-10-2018 LH59_00010 6bd0f0fa2f1a3867dbaeb6c110d31dc6 369 SUPERFAMILY SSF55979 248 369 3.93E-33 T 14-10-2018 LH59_00010 6bd0f0fa2f1a3867dbaeb6c110d31dc6 369 SMART SM00480 18 365 7.1E-105 T 14-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 LH59_00010 6bd0f0fa2f1a3867dbaeb6c110d31dc6 369 Pfam PF02767 DNA polymerase III beta subunit, central domain 132 245 1.3E-33 T 14-10-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 LH59_00010 6bd0f0fa2f1a3867dbaeb6c110d31dc6 369 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 7 120 2.3E-26 T 14-10-2018 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 LH59_00010 6bd0f0fa2f1a3867dbaeb6c110d31dc6 369 Gene3D G3DSA:3.10.150.10 127 249 1.3E-36 T 14-10-2018 LH59_18430 25d1692526d1bfe49ed8bcecd07ce898 191 Gene3D G3DSA:3.40.630.30 5 176 3.4E-34 T 14-10-2018 LH59_18430 25d1692526d1bfe49ed8bcecd07ce898 191 Pfam PF13302 Acetyltransferase (GNAT) domain 14 153 4.4E-22 T 14-10-2018 IPR000182 GNAT domain LH59_18430 25d1692526d1bfe49ed8bcecd07ce898 191 SUPERFAMILY SSF55729 9 156 1.73E-28 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_08215 e9e06e9d2dedecd50e5e25bf1801202c 372 Pfam PF03054 tRNA methyl transferase 10 371 4.6E-130 T 14-10-2018 LH59_08215 e9e06e9d2dedecd50e5e25bf1801202c 372 Gene3D G3DSA:3.40.50.620 1 219 1.5E-89 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LH59_08215 e9e06e9d2dedecd50e5e25bf1801202c 372 Gene3D G3DSA:2.30.30.280 220 292 1.2E-26 T 14-10-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 LH59_08215 e9e06e9d2dedecd50e5e25bf1801202c 372 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 10 371 1.6E-128 T 14-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 LH59_08215 e9e06e9d2dedecd50e5e25bf1801202c 372 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 9 372 38.821 T 14-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 LH59_08215 e9e06e9d2dedecd50e5e25bf1801202c 372 Gene3D G3DSA:2.40.30.10 294 372 2.1E-23 T 14-10-2018 LH59_08215 e9e06e9d2dedecd50e5e25bf1801202c 372 SUPERFAMILY SSF52402 7 251 1.04E-57 T 14-10-2018 LH59_00135 d79505c890799e5e24bf78c77942ec10 390 Gene3D G3DSA:3.30.9.10 87 313 1.8E-88 T 14-10-2018 LH59_00135 d79505c890799e5e24bf78c77942ec10 390 Pfam PF01266 FAD dependent oxidoreductase 9 350 2.4E-56 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 LH59_00135 d79505c890799e5e24bf78c77942ec10 390 SUPERFAMILY SSF51905 7 369 3.28E-52 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_00135 d79505c890799e5e24bf78c77942ec10 390 Gene3D G3DSA:3.50.50.60 9 357 1.8E-88 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_00135 d79505c890799e5e24bf78c77942ec10 390 SUPERFAMILY SSF54373 231 306 1.57E-6 T 14-10-2018 LH59_21490 f92f679dbf740e96a68220e226ef9d3b 383 Gene3D G3DSA:2.60.410.10 276 364 3.4E-20 T 14-10-2018 IPR037167 D-Ala-D-Ala carboxypeptidase, C-terminal domain superfamily GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 LH59_21490 f92f679dbf740e96a68220e226ef9d3b 383 SUPERFAMILY SSF56601 5 276 3.95E-76 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like LH59_21490 f92f679dbf740e96a68220e226ef9d3b 383 SUPERFAMILY SSF69189 276 366 9.42E-19 T 14-10-2018 IPR015956 Penicillin-binding protein, C-terminal domain superfamily GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 LH59_21490 f92f679dbf740e96a68220e226ef9d3b 383 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 276 363 4.2E-16 T 14-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 LH59_21490 f92f679dbf740e96a68220e226ef9d3b 383 SMART SM00936 276 364 4.6E-21 T 14-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 LH59_21490 f92f679dbf740e96a68220e226ef9d3b 383 Gene3D G3DSA:3.40.710.10 6 275 3.3E-89 T 14-10-2018 LH59_21490 f92f679dbf740e96a68220e226ef9d3b 383 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 138 151 3.9E-19 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 LH59_21490 f92f679dbf740e96a68220e226ef9d3b 383 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 56 67 3.9E-19 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 LH59_21490 f92f679dbf740e96a68220e226ef9d3b 383 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 111 128 3.9E-19 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 LH59_21490 f92f679dbf740e96a68220e226ef9d3b 383 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 24 255 5.7E-73 T 14-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 LH59_19585 9cd8d525b8a6ea18f4884a9da89f771f 367 SMART SM00922 147 244 2.5E-26 T 14-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal LH59_19585 9cd8d525b8a6ea18f4884a9da89f771f 367 SUPERFAMILY SSF51604 115 360 6.94E-77 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily LH59_19585 9cd8d525b8a6ea18f4884a9da89f771f 367 Gene3D G3DSA:3.20.20.120 124 351 4.8E-82 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily LH59_19585 9cd8d525b8a6ea18f4884a9da89f771f 367 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 22 127 4.4E-21 T 14-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain LH59_19585 9cd8d525b8a6ea18f4884a9da89f771f 367 Pfam PF13378 Enolase C-terminal domain-like 150 353 2.4E-67 T 14-10-2018 IPR029065 Enolase C-terminal domain-like LH59_19585 9cd8d525b8a6ea18f4884a9da89f771f 367 Gene3D G3DSA:3.30.390.10 1 123 3.6E-27 T 14-10-2018 IPR029017 Enolase-like, N-terminal LH59_19585 9cd8d525b8a6ea18f4884a9da89f771f 367 SUPERFAMILY SSF54826 3 128 3.98E-30 T 14-10-2018 LH59_02880 29cb59da91a154edaba055776714ae94 164 ProSitePatterns PS01117 MarR-type HTH domain signature. 79 113 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site LH59_02880 29cb59da91a154edaba055776714ae94 164 SUPERFAMILY SSF46785 13 150 1.9E-29 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_02880 29cb59da91a154edaba055776714ae94 164 Pfam PF01047 MarR family 47 104 7.3E-13 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_02880 29cb59da91a154edaba055776714ae94 164 Gene3D G3DSA:1.10.10.10 7 154 7.0E-35 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_02880 29cb59da91a154edaba055776714ae94 164 SMART SM00347 39 140 5.5E-20 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_02880 29cb59da91a154edaba055776714ae94 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 100 116 9.5E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_02880 29cb59da91a154edaba055776714ae94 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 80 9.5E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_02880 29cb59da91a154edaba055776714ae94 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 81 96 9.5E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_11325 4c42dd77a4ad1674fd34b3f4edcbaf1d 166 Pfam PF01584 CheW-like domain 18 155 3.5E-36 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 LH59_11325 4c42dd77a4ad1674fd34b3f4edcbaf1d 166 Gene3D G3DSA:2.30.30.40 20 147 4.1E-39 T 14-10-2018 LH59_11325 4c42dd77a4ad1674fd34b3f4edcbaf1d 166 SUPERFAMILY SSF50341 18 158 1.57E-38 T 14-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 LH59_11325 4c42dd77a4ad1674fd34b3f4edcbaf1d 166 Gene3D G3DSA:2.40.50.180 37 148 4.1E-39 T 14-10-2018 LH59_11325 4c42dd77a4ad1674fd34b3f4edcbaf1d 166 SMART SM00260 14 153 1.3E-40 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 LH59_27745 c7f8629712113caa398d9862774e1cea 72 Pfam PF01176 Translation initiation factor 1A / IF-1 9 70 1.6E-25 T 14-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 LH59_27745 c7f8629712113caa398d9862774e1cea 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 26.382 T 14-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 LH59_27745 c7f8629712113caa398d9862774e1cea 72 Gene3D G3DSA:2.40.50.140 1 72 6.2E-35 T 14-10-2018 LH59_27745 c7f8629712113caa398d9862774e1cea 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 71 4.8E-35 T 14-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 LH59_27745 c7f8629712113caa398d9862774e1cea 72 SUPERFAMILY SSF50249 1 70 8.81E-26 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_19460 129ca22f1ca7845d495837d87595404d 500 Pfam PF00392 Bacterial regulatory proteins, gntR family 22 85 1.0E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_19460 129ca22f1ca7845d495837d87595404d 500 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 59 3.4E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_19460 129ca22f1ca7845d495837d87595404d 500 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 59 75 3.4E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_19460 129ca22f1ca7845d495837d87595404d 500 Gene3D G3DSA:1.10.10.10 12 86 7.0E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_19460 129ca22f1ca7845d495837d87595404d 500 Pfam PF00155 Aminotransferase class I and II 171 448 2.0E-20 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LH59_19460 129ca22f1ca7845d495837d87595404d 500 SUPERFAMILY SSF53383 130 487 2.11E-76 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_19460 129ca22f1ca7845d495837d87595404d 500 SMART SM00345 26 85 3.8E-12 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_19460 129ca22f1ca7845d495837d87595404d 500 SUPERFAMILY SSF46785 16 87 1.31E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_19460 129ca22f1ca7845d495837d87595404d 500 Gene3D G3DSA:3.40.640.10 124 481 1.3E-106 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_05805 563e2a50b0490752a1f8405dcb589694 237 Pfam PF09313 Domain of unknown function (DUF1971) 146 212 3.2E-17 T 14-10-2018 IPR015392 Domain of unknown function DUF1971 LH59_05805 563e2a50b0490752a1f8405dcb589694 237 Gene3D G3DSA:2.60.120.10 135 234 2.1E-24 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_05805 563e2a50b0490752a1f8405dcb589694 237 Gene3D G3DSA:1.10.490.10 11 128 1.7E-34 T 14-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 LH59_05805 563e2a50b0490752a1f8405dcb589694 237 SUPERFAMILY SSF46458 15 121 3.29E-23 T 14-10-2018 IPR009050 Globin-like superfamily LH59_05805 563e2a50b0490752a1f8405dcb589694 237 SUPERFAMILY SSF51197 137 224 4.26E-21 T 14-10-2018 LH59_04045 d1457fc94cb712333546ddcee187775c 359 Gene3D G3DSA:3.40.50.2000 162 339 7.0E-109 T 14-10-2018 LH59_04045 d1457fc94cb712333546ddcee187775c 359 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 8 145 2.2E-34 T 14-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 LH59_04045 d1457fc94cb712333546ddcee187775c 359 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 8 355 34.356 T 14-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 LH59_04045 d1457fc94cb712333546ddcee187775c 359 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 3 350 5.4E-99 T 14-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 LH59_04045 d1457fc94cb712333546ddcee187775c 359 Gene3D G3DSA:3.40.50.2000 9 345 7.0E-109 T 14-10-2018 LH59_04045 d1457fc94cb712333546ddcee187775c 359 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 185 340 9.8E-36 T 14-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 LH59_04045 d1457fc94cb712333546ddcee187775c 359 SUPERFAMILY SSF53756 7 355 1.31E-117 T 14-10-2018 LH59_19540 69e0e464b2f14079cb3cfdbedc8e98d3 282 Pfam PF09339 IclR helix-turn-helix domain 31 81 4.2E-13 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_19540 69e0e464b2f14079cb3cfdbedc8e98d3 282 SMART SM00346 29 118 8.9E-16 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_19540 69e0e464b2f14079cb3cfdbedc8e98d3 282 Pfam PF01614 Bacterial transcriptional regulator 147 269 2.9E-13 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal LH59_19540 69e0e464b2f14079cb3cfdbedc8e98d3 282 SUPERFAMILY SSF46785 31 98 4.85E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_19540 69e0e464b2f14079cb3cfdbedc8e98d3 282 SUPERFAMILY SSF55781 93 274 1.5E-32 T 14-10-2018 LH59_19540 69e0e464b2f14079cb3cfdbedc8e98d3 282 Gene3D G3DSA:3.30.450.40 103 278 1.9E-30 T 14-10-2018 IPR029016 GAF-like domain superfamily LH59_19540 69e0e464b2f14079cb3cfdbedc8e98d3 282 Gene3D G3DSA:1.10.10.10 23 98 1.1E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_23955 01e6619cd8d29c7c723e80d46703dabc 772 SUPERFAMILY SSF53706 12 627 1.15E-154 T 14-10-2018 LH59_23955 01e6619cd8d29c7c723e80d46703dabc 772 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 664 691 - T 14-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 LH59_23955 01e6619cd8d29c7c723e80d46703dabc 772 Pfam PF00384 Molybdopterin oxidoreductase 54 508 1.9E-68 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_23955 01e6619cd8d29c7c723e80d46703dabc 772 Gene3D G3DSA:3.90.55.10 12 558 1.0E-191 T 14-10-2018 LH59_23955 01e6619cd8d29c7c723e80d46703dabc 772 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 453 470 - T 14-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 LH59_23955 01e6619cd8d29c7c723e80d46703dabc 772 Pfam PF01568 Molydopterin dinucleotide binding domain 625 738 1.7E-24 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 LH59_23955 01e6619cd8d29c7c723e80d46703dabc 772 Gene3D G3DSA:3.40.228.10 145 591 1.0E-191 T 14-10-2018 LH59_23955 01e6619cd8d29c7c723e80d46703dabc 772 Gene3D G3DSA:2.40.40.20 599 758 1.0E-46 T 14-10-2018 LH59_23955 01e6619cd8d29c7c723e80d46703dabc 772 SUPERFAMILY SSF50692 619 761 8.36E-41 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily LH59_23955 01e6619cd8d29c7c723e80d46703dabc 772 Gene3D G3DSA:3.40.50.740 36 517 1.0E-191 T 14-10-2018 LH59_04495 b688cefe55678abbc6efaab929b8a4c0 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 321 1.6E-77 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_04495 b688cefe55678abbc6efaab929b8a4c0 325 Gene3D G3DSA:3.40.190.150 29 315 6.3E-103 T 14-10-2018 LH59_04495 b688cefe55678abbc6efaab929b8a4c0 325 PIRSF PIRSF017082 1 325 6.8E-80 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_04495 b688cefe55678abbc6efaab929b8a4c0 325 SUPERFAMILY SSF53850 112 286 1.41E-10 T 14-10-2018 LH59_04495 b688cefe55678abbc6efaab929b8a4c0 325 Gene3D G3DSA:3.40.190.10 127 250 6.3E-103 T 14-10-2018 LH59_17610 d8c57d4d48207d44d5e8f5f82e105f41 374 SUPERFAMILY SSF53187 1 369 1.57E-67 T 14-10-2018 LH59_17610 d8c57d4d48207d44d5e8f5f82e105f41 374 Gene3D G3DSA:3.40.630.10 3 357 7.9E-131 T 14-10-2018 LH59_17610 d8c57d4d48207d44d5e8f5f82e105f41 374 Pfam PF01546 Peptidase family M20/M25/M40 59 368 2.0E-46 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 LH59_17610 d8c57d4d48207d44d5e8f5f82e105f41 374 Hamap MF_01690 Succinyl-diaminopimelate desuccinylase [dapE]. 1 371 50.801 T 14-10-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 LH59_17610 d8c57d4d48207d44d5e8f5f82e105f41 374 SUPERFAMILY SSF55031 175 284 1.64E-30 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain LH59_17610 d8c57d4d48207d44d5e8f5f82e105f41 374 Gene3D G3DSA:3.30.70.360 175 288 7.9E-131 T 14-10-2018 LH59_17610 d8c57d4d48207d44d5e8f5f82e105f41 374 TIGRFAM TIGR01246 dapE_proteo: succinyl-diaminopimelate desuccinylase 2 369 7.7E-161 T 14-10-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 LH59_17610 d8c57d4d48207d44d5e8f5f82e105f41 374 Pfam PF07687 Peptidase dimerisation domain 171 278 4.5E-26 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain LH59_15915 34d4cf51e7915a85a67f5c55213b2aa0 163 SUPERFAMILY SSF55729 1 162 7.09E-26 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_15915 34d4cf51e7915a85a67f5c55213b2aa0 163 Pfam PF00583 Acetyltransferase (GNAT) family 34 141 7.6E-14 T 14-10-2018 IPR000182 GNAT domain LH59_15915 34d4cf51e7915a85a67f5c55213b2aa0 163 Gene3D G3DSA:3.40.630.30 1 163 2.5E-39 T 14-10-2018 LH59_12360 32ae01253214332e43bd845fb857bd11 254 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 44 254 34.708 T 14-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 LH59_12360 32ae01253214332e43bd845fb857bd11 254 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 175 190 - T 14-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 LH59_12360 32ae01253214332e43bd845fb857bd11 254 SUPERFAMILY SSF53335 46 251 2.39E-41 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_12360 32ae01253214332e43bd845fb857bd11 254 Gene3D G3DSA:3.40.50.150 41 253 4.4E-69 T 14-10-2018 LH59_12360 32ae01253214332e43bd845fb857bd11 254 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 45 251 9.3E-59 T 14-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 LH59_12360 32ae01253214332e43bd845fb857bd11 254 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 49 249 3.8E-56 T 14-10-2018 LH59_02200 53294ca29b95324f6d916baab2af6065 387 Pfam PF07690 Major Facilitator Superfamily 14 196 4.5E-36 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_02200 53294ca29b95324f6d916baab2af6065 387 PRINTS PR01035 Tetracycline resistance protein signature 46 65 4.2E-7 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 LH59_02200 53294ca29b95324f6d916baab2af6065 387 PRINTS PR01035 Tetracycline resistance protein signature 243 263 4.2E-7 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 LH59_02200 53294ca29b95324f6d916baab2af6065 387 PRINTS PR01035 Tetracycline resistance protein signature 135 157 4.2E-7 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 LH59_02200 53294ca29b95324f6d916baab2af6065 387 PRINTS PR01035 Tetracycline resistance protein signature 77 101 4.2E-7 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 LH59_02200 53294ca29b95324f6d916baab2af6065 387 SUPERFAMILY SSF103473 8 377 1.7E-53 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_02200 53294ca29b95324f6d916baab2af6065 387 Gene3D G3DSA:1.20.1250.20 6 382 7.4E-53 T 14-10-2018 LH59_06570 fcea4a0c6f921983a1c2cc2cc93a58e5 305 SUPERFAMILY SSF53850 92 297 1.78E-37 T 14-10-2018 LH59_06570 fcea4a0c6f921983a1c2cc2cc93a58e5 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 7.4E-15 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_06570 fcea4a0c6f921983a1c2cc2cc93a58e5 305 Gene3D G3DSA:1.10.10.10 3 90 1.2E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_06570 fcea4a0c6f921983a1c2cc2cc93a58e5 305 SUPERFAMILY SSF46785 2 79 6.53E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_06570 fcea4a0c6f921983a1c2cc2cc93a58e5 305 Pfam PF03466 LysR substrate binding domain 90 293 4.2E-37 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_06570 fcea4a0c6f921983a1c2cc2cc93a58e5 305 Gene3D G3DSA:3.40.190.290 93 294 5.9E-35 T 14-10-2018 LH59_02975 ed9358c28bd0011dfc9503151d3317da 395 SUPERFAMILY SSF53822 32 390 8.25E-85 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_02975 ed9358c28bd0011dfc9503151d3317da 395 Gene3D G3DSA:3.40.50.2300 149 367 7.4E-96 T 14-10-2018 LH59_02975 ed9358c28bd0011dfc9503151d3317da 395 Gene3D G3DSA:3.40.50.2300 32 357 7.4E-96 T 14-10-2018 LH59_02975 ed9358c28bd0011dfc9503151d3317da 395 Pfam PF13458 Periplasmic binding protein 31 367 7.3E-72 T 14-10-2018 IPR028081 Leucine-binding protein domain LH59_12315 0c6ce4f7491a7608ab2f4d796de76099 271 Gene3D G3DSA:3.40.190.10 55 252 1.6E-16 T 14-10-2018 LH59_12315 0c6ce4f7491a7608ab2f4d796de76099 271 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 53 252 3.7E-14 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_12315 0c6ce4f7491a7608ab2f4d796de76099 271 SMART SM00062 35 256 7.7E-4 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_12315 0c6ce4f7491a7608ab2f4d796de76099 271 SUPERFAMILY SSF53850 27 253 1.49E-17 T 14-10-2018 LH59_12315 0c6ce4f7491a7608ab2f4d796de76099 271 Gene3D G3DSA:3.40.190.10 121 216 1.6E-16 T 14-10-2018 LH59_02010 4f3438ce66cd36c21175cc2b5918b8c1 179 Pfam PF00213 ATP synthase delta (OSCP) subunit 7 177 5.8E-51 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 LH59_02010 4f3438ce66cd36c21175cc2b5918b8c1 179 Gene3D G3DSA:1.10.520.20 2 108 1.1E-27 T 14-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 LH59_02010 4f3438ce66cd36c21175cc2b5918b8c1 179 Hamap MF_01416 ATP synthase subunit delta [atpD]. 3 179 20.21 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 LH59_02010 4f3438ce66cd36c21175cc2b5918b8c1 179 SUPERFAMILY SSF47928 3 107 9.94E-24 T 14-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 LH59_02010 4f3438ce66cd36c21175cc2b5918b8c1 179 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 7 177 5.5E-41 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 LH59_02010 4f3438ce66cd36c21175cc2b5918b8c1 179 PRINTS PR00125 ATP synthase delta subunit signature 137 152 1.5E-22 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 LH59_02010 4f3438ce66cd36c21175cc2b5918b8c1 179 PRINTS PR00125 ATP synthase delta subunit signature 76 87 1.5E-22 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 LH59_02010 4f3438ce66cd36c21175cc2b5918b8c1 179 PRINTS PR00125 ATP synthase delta subunit signature 152 170 1.5E-22 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 LH59_02010 4f3438ce66cd36c21175cc2b5918b8c1 179 PRINTS PR00125 ATP synthase delta subunit signature 7 26 1.5E-22 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 LH59_02010 4f3438ce66cd36c21175cc2b5918b8c1 179 PRINTS PR00125 ATP synthase delta subunit signature 87 101 1.5E-22 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 LH59_25950 e9190f6fcfabd0675d0d7697ec388012 91 Pfam PF02426 Muconolactone delta-isomerase 1 89 7.7E-42 T 14-10-2018 IPR026029 Muconolactone isomerase domain KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 LH59_25950 e9190f6fcfabd0675d0d7697ec388012 91 SUPERFAMILY SSF54909 1 91 2.68E-38 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel LH59_25950 e9190f6fcfabd0675d0d7697ec388012 91 TIGRFAM TIGR03221 muco_delta: muconolactone delta-isomerase 2 91 3.4E-49 T 14-10-2018 IPR003464 Muconolactone delta-isomerase GO:0006725 KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 LH59_25950 e9190f6fcfabd0675d0d7697ec388012 91 PIRSF PIRSF001486 1 91 3.0E-46 T 14-10-2018 IPR003464 Muconolactone delta-isomerase GO:0006725 KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 LH59_25950 e9190f6fcfabd0675d0d7697ec388012 91 ProDom PD006619 ISOMERASE MUCONOLACTONE DELTA-ISOMERASE HYDROCARBONS MIASE AROMATIC CATABOLISM METHYLMUCONOLACTONE DIRECT SEQUENCING 1 57 1.0E-12 T 14-10-2018 IPR003464 Muconolactone delta-isomerase GO:0006725 KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 LH59_25950 e9190f6fcfabd0675d0d7697ec388012 91 Gene3D G3DSA:3.30.70.1060 1 91 1.4E-37 T 14-10-2018 LH59_17890 284cc374861f66cc4a8275e7e1d9546d 1526 Pfam PF07703 Alpha-2-macroglobulin family N-terminal region 604 747 4.0E-13 T 14-10-2018 IPR011625 Alpha-2-macroglobulin, N-terminal 2 LH59_17890 284cc374861f66cc4a8275e7e1d9546d 1526 PIRSF PIRSF038980 1 1520 0.0 T 14-10-2018 IPR026284 Alpha-2-macroglobulin domain protein, bacteria LH59_17890 284cc374861f66cc4a8275e7e1d9546d 1526 SUPERFAMILY SSF48239 1015 1298 4.26E-43 T 14-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid LH59_17890 284cc374861f66cc4a8275e7e1d9546d 1526 Pfam PF10569 Alpha-macro-globulin thiol-ester bond-forming region 1016 1038 1.9E-5 T 14-10-2018 IPR019565 Alpha-2-macroglobulin, thiol-ester bond-forming LH59_17890 284cc374861f66cc4a8275e7e1d9546d 1526 SMART SM01360 809 898 5.1E-29 T 14-10-2018 IPR001599 Alpha-2-macroglobulin GO:0004866 LH59_17890 284cc374861f66cc4a8275e7e1d9546d 1526 Pfam PF00207 Alpha-2-macroglobulin family 817 898 7.4E-13 T 14-10-2018 IPR001599 Alpha-2-macroglobulin GO:0004866 LH59_17890 284cc374861f66cc4a8275e7e1d9546d 1526 Pfam PF11974 Alpha-2-macroglobulin MG1 domain 143 236 3.8E-20 T 14-10-2018 LH59_17890 284cc374861f66cc4a8275e7e1d9546d 1526 Gene3D G3DSA:2.60.40.1930 242 344 6.9E-5 T 14-10-2018 LH59_17890 284cc374861f66cc4a8275e7e1d9546d 1526 Pfam PF01835 MG2 domain 243 340 2.8E-17 T 14-10-2018 IPR002890 Alpha-2-macroglobulin, N-terminal GO:0004866 LH59_17890 284cc374861f66cc4a8275e7e1d9546d 1526 Gene3D G3DSA:1.50.10.20 1011 1302 1.3E-32 T 14-10-2018 LH59_17890 284cc374861f66cc4a8275e7e1d9546d 1526 Pfam PF07678 A-macroglobulin complement component 1070 1149 6.5E-10 T 14-10-2018 IPR011626 Alpha-macroglobulin complement component GO:0005615 LH59_17890 284cc374861f66cc4a8275e7e1d9546d 1526 SMART SM01359 603 747 3.3E-34 T 14-10-2018 IPR011625 Alpha-2-macroglobulin, N-terminal 2 LH59_26500 e937e0b813e94a728788edfa83531fc1 170 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 5 161 4.4E-55 T 14-10-2018 IPR023635 Peptide deformylase LH59_26500 e937e0b813e94a728788edfa83531fc1 170 Hamap MF_00163 Peptide deformylase [def]. 2 163 31.274 T 14-10-2018 IPR023635 Peptide deformylase LH59_26500 e937e0b813e94a728788edfa83531fc1 170 Pfam PF01327 Polypeptide deformylase 5 153 4.7E-52 T 14-10-2018 IPR023635 Peptide deformylase LH59_26500 e937e0b813e94a728788edfa83531fc1 170 PRINTS PR01576 Peptide deformylase signature 33 62 1.9E-36 T 14-10-2018 IPR023635 Peptide deformylase LH59_26500 e937e0b813e94a728788edfa83531fc1 170 PRINTS PR01576 Peptide deformylase signature 121 150 1.9E-36 T 14-10-2018 IPR023635 Peptide deformylase LH59_26500 e937e0b813e94a728788edfa83531fc1 170 PRINTS PR01576 Peptide deformylase signature 90 101 1.9E-36 T 14-10-2018 IPR023635 Peptide deformylase LH59_26500 e937e0b813e94a728788edfa83531fc1 170 PRINTS PR01576 Peptide deformylase signature 102 120 1.9E-36 T 14-10-2018 IPR023635 Peptide deformylase LH59_26500 e937e0b813e94a728788edfa83531fc1 170 PIRSF PIRSF004749 1 169 4.3E-57 T 14-10-2018 IPR023635 Peptide deformylase LH59_26500 e937e0b813e94a728788edfa83531fc1 170 SUPERFAMILY SSF56420 2 164 1.57E-63 T 14-10-2018 IPR036821 Peptide deformylase superfamily LH59_26500 e937e0b813e94a728788edfa83531fc1 170 Gene3D G3DSA:3.90.45.10 1 168 2.1E-65 T 14-10-2018 IPR036821 Peptide deformylase superfamily LH59_07970 f942f55c47738ff85980497b3d4fadef 246 Hamap MF_01114 Regulatory protein RecX [recX]. 102 246 13.827 T 14-10-2018 IPR003783 Regulatory protein RecX GO:0006282 LH59_07970 f942f55c47738ff85980497b3d4fadef 246 Gene3D G3DSA:1.10.10.10 106 149 4.2E-11 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_07970 f942f55c47738ff85980497b3d4fadef 246 Gene3D G3DSA:1.10.10.10 153 193 3.2E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_07970 f942f55c47738ff85980497b3d4fadef 246 Gene3D G3DSA:1.10.10.10 198 242 6.2E-13 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_07970 f942f55c47738ff85980497b3d4fadef 246 Pfam PF02631 RecX family 129 242 2.8E-27 T 14-10-2018 IPR003783 Regulatory protein RecX GO:0006282 LH59_14430 91b7e86d4b78dee58d884d3c232b9296 242 SUPERFAMILY SSF161098 49 231 3.27E-29 T 14-10-2018 IPR035906 MetI-like superfamily LH59_14430 91b7e86d4b78dee58d884d3c232b9296 242 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 71 239 2.7E-21 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_14430 91b7e86d4b78dee58d884d3c232b9296 242 Gene3D G3DSA:1.10.3720.10 51 239 8.0E-24 T 14-10-2018 IPR035906 MetI-like superfamily LH59_24015 d01dcd4a1e289a2da8c4edc69ec64b71 101 Pfam PF05957 Bacterial protein of unknown function (DUF883) 10 93 1.3E-19 T 14-10-2018 IPR010279 Inner membrane protein YqjD/ElaB GO:0043022 LH59_17695 d640c3ba15323bbb863c90c7228c8a07 321 Gene3D G3DSA:3.40.50.620 8 195 2.4E-57 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LH59_17695 d640c3ba15323bbb863c90c7228c8a07 321 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 21 316 1.9E-86 T 14-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 LH59_17695 d640c3ba15323bbb863c90c7228c8a07 321 SUPERFAMILY SSF82114 184 317 5.45E-38 T 14-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 LH59_17695 d640c3ba15323bbb863c90c7228c8a07 321 Gene3D G3DSA:2.40.30.30 197 319 3.1E-35 T 14-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 LH59_17695 d640c3ba15323bbb863c90c7228c8a07 321 Pfam PF01687 Riboflavin kinase 193 316 1.7E-33 T 14-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 LH59_17695 d640c3ba15323bbb863c90c7228c8a07 321 SMART SM00904 192 317 2.8E-52 T 14-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 LH59_17695 d640c3ba15323bbb863c90c7228c8a07 321 SUPERFAMILY SSF52374 20 184 1.85E-30 T 14-10-2018 LH59_17695 d640c3ba15323bbb863c90c7228c8a07 321 Pfam PF06574 FAD synthetase 16 175 1.6E-48 T 14-10-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 LH59_17695 d640c3ba15323bbb863c90c7228c8a07 321 PIRSF PIRSF004491 5 320 3.0E-94 T 14-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 LH59_23925 1b857becc83d05b20276b13ef8551bdd 301 SMART SM00342 213 296 4.9E-21 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_23925 1b857becc83d05b20276b13ef8551bdd 301 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 251 292 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 LH59_23925 1b857becc83d05b20276b13ef8551bdd 301 Gene3D G3DSA:1.10.10.60 194 301 1.5E-22 T 14-10-2018 LH59_23925 1b857becc83d05b20276b13ef8551bdd 301 SUPERFAMILY SSF46689 251 297 1.3E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_23925 1b857becc83d05b20276b13ef8551bdd 301 Pfam PF12833 Helix-turn-helix domain 220 297 1.3E-19 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_04440 b29fbd28a5359a714ee8ee97b64609fc 303 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 4 286 5.2E-149 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 LH59_04440 b29fbd28a5359a714ee8ee97b64609fc 303 Gene3D G3DSA:3.30.930.10 1 210 9.5E-111 T 14-10-2018 LH59_04440 b29fbd28a5359a714ee8ee97b64609fc 303 SUPERFAMILY SSF55681 3 286 1.2E-130 T 14-10-2018 LH59_04440 b29fbd28a5359a714ee8ee97b64609fc 303 Gene3D G3DSA:1.20.58.180 211 292 1.2E-34 T 14-10-2018 LH59_04440 b29fbd28a5359a714ee8ee97b64609fc 303 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 3 293 4.6E-157 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 LH59_04440 b29fbd28a5359a714ee8ee97b64609fc 303 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 2 287 60.075 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 LH59_04440 b29fbd28a5359a714ee8ee97b64609fc 303 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 56 71 4.8E-66 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 LH59_04440 b29fbd28a5359a714ee8ee97b64609fc 303 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 108 132 4.8E-66 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 LH59_04440 b29fbd28a5359a714ee8ee97b64609fc 303 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 77 97 4.8E-66 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 LH59_04440 b29fbd28a5359a714ee8ee97b64609fc 303 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 247 263 4.8E-66 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 LH59_04440 b29fbd28a5359a714ee8ee97b64609fc 303 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 134 154 4.8E-66 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 LH59_04440 b29fbd28a5359a714ee8ee97b64609fc 303 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 157 172 4.8E-66 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 LH59_02515 ac80317bf68e50f050b5fbac0fe8acc1 443 SUPERFAMILY SSF56954 28 439 2.22E-81 T 14-10-2018 LH59_02515 ac80317bf68e50f050b5fbac0fe8acc1 443 Pfam PF02321 Outer membrane efflux protein 28 215 5.8E-22 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 LH59_02515 ac80317bf68e50f050b5fbac0fe8acc1 443 Pfam PF02321 Outer membrane efflux protein 240 423 4.7E-23 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 LH59_02515 ac80317bf68e50f050b5fbac0fe8acc1 443 Gene3D G3DSA:1.20.1600.10 26 443 1.9E-106 T 14-10-2018 LH59_02515 ac80317bf68e50f050b5fbac0fe8acc1 443 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 25 439 2.8E-90 T 14-10-2018 IPR010130 Type I secretion outer membrane protein, TolC GO:0015562|GO:0019867|GO:0055085 LH59_09610 48bcf9167a6e863a7c1e6d2b3ef59cc4 650 PRINTS PR01047 Threonyl-tRNA synthetase signature 511 524 1.4E-52 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 LH59_09610 48bcf9167a6e863a7c1e6d2b3ef59cc4 650 PRINTS PR01047 Threonyl-tRNA synthetase signature 538 550 1.4E-52 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 LH59_09610 48bcf9167a6e863a7c1e6d2b3ef59cc4 650 PRINTS PR01047 Threonyl-tRNA synthetase signature 366 389 1.4E-52 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 LH59_09610 48bcf9167a6e863a7c1e6d2b3ef59cc4 650 PRINTS PR01047 Threonyl-tRNA synthetase signature 468 496 1.4E-52 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 LH59_09610 48bcf9167a6e863a7c1e6d2b3ef59cc4 650 PRINTS PR01047 Threonyl-tRNA synthetase signature 333 361 1.4E-52 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 LH59_09610 48bcf9167a6e863a7c1e6d2b3ef59cc4 650 Gene3D G3DSA:3.10.20.30 1 67 1.3E-18 T 14-10-2018 IPR012675 Beta-grasp domain superfamily LH59_09610 48bcf9167a6e863a7c1e6d2b3ef59cc4 650 Pfam PF03129 Anticodon binding domain 545 634 5.5E-19 T 14-10-2018 IPR004154 Anticodon-binding LH59_09610 48bcf9167a6e863a7c1e6d2b3ef59cc4 650 SUPERFAMILY SSF55186 69 245 6.54E-69 T 14-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 LH59_09610 48bcf9167a6e863a7c1e6d2b3ef59cc4 650 Gene3D G3DSA:3.30.54.20 135 191 2.2E-65 T 14-10-2018 LH59_09610 48bcf9167a6e863a7c1e6d2b3ef59cc4 650 Pfam PF02824 TGS domain 2 66 2.7E-8 T 14-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 LH59_09610 48bcf9167a6e863a7c1e6d2b3ef59cc4 650 SUPERFAMILY SSF52954 534 637 1.13E-29 T 14-10-2018 LH59_09610 48bcf9167a6e863a7c1e6d2b3ef59cc4 650 SMART SM00863 174 223 7.2E-25 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 LH59_09610 48bcf9167a6e863a7c1e6d2b3ef59cc4 650 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 71 638 34.169 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 LH59_09610 48bcf9167a6e863a7c1e6d2b3ef59cc4 650 Gene3D G3DSA:3.30.980.10 74 226 2.2E-65 T 14-10-2018 LH59_09610 48bcf9167a6e863a7c1e6d2b3ef59cc4 650 SUPERFAMILY SSF55681 247 530 1.3E-99 T 14-10-2018 LH59_09610 48bcf9167a6e863a7c1e6d2b3ef59cc4 650 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 322 533 4.7E-43 T 14-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 LH59_09610 48bcf9167a6e863a7c1e6d2b3ef59cc4 650 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 77 635 2.4E-214 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 LH59_09610 48bcf9167a6e863a7c1e6d2b3ef59cc4 650 Gene3D G3DSA:3.30.930.10 227 535 1.7E-124 T 14-10-2018 LH59_09610 48bcf9167a6e863a7c1e6d2b3ef59cc4 650 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 175 223 2.6E-15 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 LH59_09610 48bcf9167a6e863a7c1e6d2b3ef59cc4 650 Gene3D G3DSA:3.40.50.800 536 645 1.5E-29 T 14-10-2018 IPR036621 Anticodon-binding domain superfamily LH59_09610 48bcf9167a6e863a7c1e6d2b3ef59cc4 650 SUPERFAMILY SSF81271 2 66 2.42E-11 T 14-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 LH59_15800 77068fc6af759c08e172b931b66143dd 539 Gene3D G3DSA:1.10.287.950 209 539 2.0E-63 T 14-10-2018 LH59_15800 77068fc6af759c08e172b931b66143dd 539 SMART SM00304 210 262 5.9E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_15800 77068fc6af759c08e172b931b66143dd 539 SMART SM00283 270 538 1.7E-50 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 LH59_15800 77068fc6af759c08e172b931b66143dd 539 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 343 504 1.5E-34 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 LH59_15800 77068fc6af759c08e172b931b66143dd 539 Pfam PF12729 Four helix bundle sensory module for signal transduction 3 175 2.7E-22 T 14-10-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain LH59_15800 77068fc6af759c08e172b931b66143dd 539 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 298 327 1.5E-19 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_15800 77068fc6af759c08e172b931b66143dd 539 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 8 33 1.5E-19 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_15800 77068fc6af759c08e172b931b66143dd 539 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 404 433 1.5E-19 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_15800 77068fc6af759c08e172b931b66143dd 539 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 375 402 1.5E-19 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_15800 77068fc6af759c08e172b931b66143dd 539 SUPERFAMILY SSF58104 230 539 5.49E-62 T 14-10-2018 LH59_07455 0aadd64c7060101d941b30b6f4599e34 292 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 32 282 6.6E-59 T 14-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 LH59_07455 0aadd64c7060101d941b30b6f4599e34 292 SUPERFAMILY SSF50249 1 55 7.2E-6 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_07455 0aadd64c7060101d941b30b6f4599e34 292 Gene3D G3DSA:2.40.50.140 1 52 1.7E-7 T 14-10-2018 LH59_07455 0aadd64c7060101d941b30b6f4599e34 292 Hamap MF_01820 Small ribosomal subunit biogenesis GTPase RsgA [rsgA]. 1 289 31.873 T 14-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 LH59_07455 0aadd64c7060101d941b30b6f4599e34 292 Gene3D G3DSA:1.10.40.50 225 292 1.7E-19 T 14-10-2018 LH59_07455 0aadd64c7060101d941b30b6f4599e34 292 Pfam PF03193 RsgA GTPase 51 224 1.2E-45 T 14-10-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 LH59_07455 0aadd64c7060101d941b30b6f4599e34 292 Gene3D G3DSA:3.40.50.300 54 224 5.3E-36 T 14-10-2018 LH59_07455 0aadd64c7060101d941b30b6f4599e34 292 SUPERFAMILY SSF52540 68 284 1.51E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_11250 5006d53e11c29a672366436724e02a2c 555 SUPERFAMILY SSF47005 248 292 8.63E-12 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 LH59_11250 5006d53e11c29a672366436724e02a2c 555 SUPERFAMILY SSF52777 317 553 4.45E-85 T 14-10-2018 LH59_11250 5006d53e11c29a672366436724e02a2c 555 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 LH59_11250 5006d53e11c29a672366436724e02a2c 555 Pfam PF00364 Biotin-requiring enzyme 121 191 5.6E-19 T 14-10-2018 IPR000089 Biotin/lipoyl attachment LH59_11250 5006d53e11c29a672366436724e02a2c 555 Pfam PF00364 Biotin-requiring enzyme 6 76 4.1E-20 T 14-10-2018 IPR000089 Biotin/lipoyl attachment LH59_11250 5006d53e11c29a672366436724e02a2c 555 SUPERFAMILY SSF51230 119 212 4.71E-22 T 14-10-2018 IPR011053 Single hybrid motif LH59_11250 5006d53e11c29a672366436724e02a2c 555 SUPERFAMILY SSF51230 3 96 1.83E-22 T 14-10-2018 IPR011053 Single hybrid motif LH59_11250 5006d53e11c29a672366436724e02a2c 555 Gene3D G3DSA:4.10.320.10 254 297 2.0E-18 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 LH59_11250 5006d53e11c29a672366436724e02a2c 555 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 143 172 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 LH59_11250 5006d53e11c29a672366436724e02a2c 555 Gene3D G3DSA:3.30.559.10 312 555 1.2E-95 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 LH59_11250 5006d53e11c29a672366436724e02a2c 555 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 330 554 1.4E-82 T 14-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 LH59_11250 5006d53e11c29a672366436724e02a2c 555 TIGRFAM TIGR01348 PDHac_trf_long: dihydrolipoyllysine-residue acetyltransferase 98 555 8.9E-196 T 14-10-2018 IPR006256 Dihydrolipoamide acetyltransferase pyruvate dehydrogenase complex GO:0004742|GO:0006096|GO:0045254 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 LH59_11250 5006d53e11c29a672366436724e02a2c 555 Gene3D G3DSA:2.40.50.100 3 82 4.3E-20 T 14-10-2018 LH59_11250 5006d53e11c29a672366436724e02a2c 555 Gene3D G3DSA:2.40.50.100 119 196 3.6E-19 T 14-10-2018 LH59_11250 5006d53e11c29a672366436724e02a2c 555 Pfam PF02817 e3 binding domain 253 288 5.3E-16 T 14-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 LH59_05655 c2be69a7d210b55d974426ea5b1cc2d1 257 Pfam PF01066 CDP-alcohol phosphatidyltransferase 19 82 1.0E-13 T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 LH59_05655 c2be69a7d210b55d974426ea5b1cc2d1 257 Gene3D G3DSA:1.20.120.1760 12 186 5.2E-15 T 14-10-2018 LH59_05655 c2be69a7d210b55d974426ea5b1cc2d1 257 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 60 82 - T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 LH59_05655 c2be69a7d210b55d974426ea5b1cc2d1 257 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 26 165 2.1E-33 T 14-10-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 LH59_06090 5ca47d29048147929069ebe6995e86bd 148 Gene3D G3DSA:3.10.129.10 19 148 9.4E-36 T 14-10-2018 LH59_06090 5ca47d29048147929069ebe6995e86bd 148 SUPERFAMILY SSF54637 15 147 6.47E-24 T 14-10-2018 IPR029069 HotDog domain superfamily LH59_06090 5ca47d29048147929069ebe6995e86bd 148 Pfam PF03061 Thioesterase superfamily 61 121 1.5E-8 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 LH59_06090 5ca47d29048147929069ebe6995e86bd 148 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 34 119 4.0E-11 T 14-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 LH59_00990 efe153635f5cfdca9fcaf92254c585c4 265 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_00990 efe153635f5cfdca9fcaf92254c585c4 265 SMART SM00382 44 224 6.0E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_00990 efe153635f5cfdca9fcaf92254c585c4 265 Gene3D G3DSA:3.40.50.300 1 257 1.3E-62 T 14-10-2018 LH59_00990 efe153635f5cfdca9fcaf92254c585c4 265 Pfam PF00005 ABC transporter 35 177 4.4E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_00990 efe153635f5cfdca9fcaf92254c585c4 265 SUPERFAMILY SSF52540 26 240 5.65E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_16525 b0fd8368e40791ca36af5b81a72309d9 432 SUPERFAMILY SSF53474 66 426 3.47E-32 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_16525 b0fd8368e40791ca36af5b81a72309d9 432 PIRSF PIRSF016521 3 432 3.7E-111 T 14-10-2018 IPR016662 Acyl-CoA thioesterase, long chain GO:0006637|GO:0016790 LH59_16525 b0fd8368e40791ca36af5b81a72309d9 432 Gene3D G3DSA:3.40.50.1820 132 427 1.1E-55 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_16525 b0fd8368e40791ca36af5b81a72309d9 432 Pfam PF08840 BAAT / Acyl-CoA thioester hydrolase C terminal 201 429 7.5E-34 T 14-10-2018 IPR014940 BAAT/Acyl-CoA thioester hydrolase C-terminal LH59_16525 b0fd8368e40791ca36af5b81a72309d9 432 Gene3D G3DSA:2.60.40.2240 1 131 5.0E-26 T 14-10-2018 LH59_16525 b0fd8368e40791ca36af5b81a72309d9 432 Pfam PF04775 Acyl-CoA thioester hydrolase/BAAT N-terminal region 17 135 7.4E-25 T 14-10-2018 IPR006862 Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase LH59_17080 d2a6a7632c02303fbe48128aff15a005 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 1.8E-19 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_17080 d2a6a7632c02303fbe48128aff15a005 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.8E-19 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_17080 d2a6a7632c02303fbe48128aff15a005 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.8E-19 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_17080 d2a6a7632c02303fbe48128aff15a005 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.8E-19 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_17080 d2a6a7632c02303fbe48128aff15a005 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.8E-19 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_17080 d2a6a7632c02303fbe48128aff15a005 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 1.8E-19 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_17080 d2a6a7632c02303fbe48128aff15a005 251 Gene3D G3DSA:3.40.50.720 1 249 2.6E-53 T 14-10-2018 LH59_17080 d2a6a7632c02303fbe48128aff15a005 251 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 191 0.0062 T 14-10-2018 LH59_17080 d2a6a7632c02303fbe48128aff15a005 251 Pfam PF00106 short chain dehydrogenase 5 199 1.6E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_17080 d2a6a7632c02303fbe48128aff15a005 251 SUPERFAMILY SSF51735 3 238 6.07E-45 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_22880 f3b8b2c8b7d6ce94ed0d6a66d80de128 83 SUPERFAMILY SSF54285 6 83 2.62E-16 T 14-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp LH59_22880 f3b8b2c8b7d6ce94ed0d6a66d80de128 83 Pfam PF02597 ThiS family 9 83 1.7E-17 T 14-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 LH59_22880 f3b8b2c8b7d6ce94ed0d6a66d80de128 83 Gene3D G3DSA:3.10.20.30 6 83 5.9E-21 T 14-10-2018 IPR012675 Beta-grasp domain superfamily LH59_24125 b66cf03378a8fbab53355a6561d2e488 319 PIRSF PIRSF017082 2 318 3.9E-72 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_24125 b66cf03378a8fbab53355a6561d2e488 319 SUPERFAMILY SSF53850 116 275 9.05E-12 T 14-10-2018 LH59_24125 b66cf03378a8fbab53355a6561d2e488 319 Gene3D G3DSA:3.40.190.150 25 309 7.7E-103 T 14-10-2018 LH59_24125 b66cf03378a8fbab53355a6561d2e488 319 Gene3D G3DSA:3.40.190.10 121 244 7.7E-103 T 14-10-2018 LH59_24125 b66cf03378a8fbab53355a6561d2e488 319 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 315 5.4E-81 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_19005 28f7776ffff8c9d799240d2b7e0cc53e 320 SUPERFAMILY SSF53850 110 281 4.45E-14 T 14-10-2018 LH59_19005 28f7776ffff8c9d799240d2b7e0cc53e 320 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 44 315 2.7E-84 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_19005 28f7776ffff8c9d799240d2b7e0cc53e 320 PIRSF PIRSF017082 1 320 1.2E-80 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_19005 28f7776ffff8c9d799240d2b7e0cc53e 320 Gene3D G3DSA:3.40.190.10 122 245 5.1E-107 T 14-10-2018 LH59_19005 28f7776ffff8c9d799240d2b7e0cc53e 320 Gene3D G3DSA:3.40.190.150 25 310 5.1E-107 T 14-10-2018 LH59_08635 fd562c3ffa4bcdd603bc820e4276b42b 375 Gene3D G3DSA:2.40.50.140 300 339 9.7E-11 T 14-10-2018 LH59_08635 fd562c3ffa4bcdd603bc820e4276b42b 375 SUPERFAMILY SSF50331 251 372 2.49E-14 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal LH59_08635 fd562c3ffa4bcdd603bc820e4276b42b 375 Pfam PF00005 ABC transporter 34 175 4.1E-35 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_08635 fd562c3ffa4bcdd603bc820e4276b42b 375 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 48 373 2.9E-124 T 14-10-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 LH59_08635 fd562c3ffa4bcdd603bc820e4276b42b 375 SUPERFAMILY SSF52540 18 257 3.47E-86 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_08635 fd562c3ffa4bcdd603bc820e4276b42b 375 Pfam PF08402 TOBE domain 293 373 3.6E-15 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 LH59_08635 fd562c3ffa4bcdd603bc820e4276b42b 375 Gene3D G3DSA:3.40.50.300 18 235 5.5E-67 T 14-10-2018 LH59_08635 fd562c3ffa4bcdd603bc820e4276b42b 375 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_08635 fd562c3ffa4bcdd603bc820e4276b42b 375 Gene3D G3DSA:2.40.50.940 236 299 9.7E-11 T 14-10-2018 LH59_08635 fd562c3ffa4bcdd603bc820e4276b42b 375 SMART SM00382 42 227 1.2E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_10505 1176882ac680c1d22a724bd97d5b2cbe 257 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 135 155 1.7E-44 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 LH59_10505 1176882ac680c1d22a724bd97d5b2cbe 257 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 218 242 1.7E-44 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 LH59_10505 1176882ac680c1d22a724bd97d5b2cbe 257 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 114 134 1.7E-44 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 LH59_10505 1176882ac680c1d22a724bd97d5b2cbe 257 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 59 76 1.7E-44 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 LH59_10505 1176882ac680c1d22a724bd97d5b2cbe 257 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 170 196 1.7E-44 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 LH59_10505 1176882ac680c1d22a724bd97d5b2cbe 257 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 76 96 1.7E-44 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 LH59_10505 1176882ac680c1d22a724bd97d5b2cbe 257 Pfam PF01578 Cytochrome C assembly protein 43 198 1.0E-27 T 14-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 LH59_10505 1176882ac680c1d22a724bd97d5b2cbe 257 TIGRFAM TIGR01191 ccmC: heme exporter protein CcmC 59 240 1.3E-65 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 LH59_12820 ab8d4beebda4f7025a69158498a2edd3 316 Pfam PF03466 LysR substrate binding domain 87 296 2.4E-49 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_12820 ab8d4beebda4f7025a69158498a2edd3 316 Gene3D G3DSA:3.40.190.10 161 271 3.3E-78 T 14-10-2018 LH59_12820 ab8d4beebda4f7025a69158498a2edd3 316 SUPERFAMILY SSF53850 88 298 4.34E-43 T 14-10-2018 LH59_12820 ab8d4beebda4f7025a69158498a2edd3 316 SUPERFAMILY SSF46785 1 86 4.59E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_12820 ab8d4beebda4f7025a69158498a2edd3 316 Gene3D G3DSA:3.40.190.10 92 294 3.3E-78 T 14-10-2018 LH59_12820 ab8d4beebda4f7025a69158498a2edd3 316 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 9.2E-19 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_12820 ab8d4beebda4f7025a69158498a2edd3 316 Gene3D G3DSA:1.10.10.10 1 85 5.1E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_12820 ab8d4beebda4f7025a69158498a2edd3 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.3E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_12820 ab8d4beebda4f7025a69158498a2edd3 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.3E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_12820 ab8d4beebda4f7025a69158498a2edd3 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.3E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_16420 b5e479578e794d7a54dc09affea4d21f 241 Gene3D G3DSA:3.40.50.720 1 231 2.4E-26 T 14-10-2018 LH59_16420 b5e479578e794d7a54dc09affea4d21f 241 SUPERFAMILY SSF51735 1 226 4.82E-22 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_16420 b5e479578e794d7a54dc09affea4d21f 241 Pfam PF13460 NAD(P)H-binding 7 218 6.1E-25 T 14-10-2018 IPR016040 NAD(P)-binding domain LH59_25160 7ce7b44861d8245fb5a864c4f99013d0 166 SUPERFAMILY SSF88659 104 163 2.4E-14 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like LH59_25160 7ce7b44861d8245fb5a864c4f99013d0 166 Gene3D G3DSA:1.10.10.10 89 166 4.7E-13 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_25160 7ce7b44861d8245fb5a864c4f99013d0 166 Gene3D G3DSA:1.10.1740.10 1 79 2.7E-9 T 14-10-2018 LH59_25160 7ce7b44861d8245fb5a864c4f99013d0 166 SUPERFAMILY SSF88946 3 76 2.28E-15 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 LH59_25160 7ce7b44861d8245fb5a864c4f99013d0 166 Pfam PF08281 Sigma-70, region 4 110 162 2.1E-16 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LH59_25160 7ce7b44861d8245fb5a864c4f99013d0 166 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 9 162 3.2E-22 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 LH59_25160 7ce7b44861d8245fb5a864c4f99013d0 166 Pfam PF04542 Sigma-70 region 2 13 79 3.3E-12 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 LH59_19645 f8f885802d836aa881989d2a428148d3 593 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 566 587 9.3E-7 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal LH59_19645 f8f885802d836aa881989d2a428148d3 593 Gene3D G3DSA:3.40.50.300 348 589 4.4E-53 T 14-10-2018 LH59_19645 f8f885802d836aa881989d2a428148d3 593 Pfam PF00005 ABC transporter 369 516 5.5E-23 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_19645 f8f885802d836aa881989d2a428148d3 593 SUPERFAMILY SSF52540 351 589 4.93E-54 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_19645 f8f885802d836aa881989d2a428148d3 593 SMART SM00382 377 565 4.4E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_19645 f8f885802d836aa881989d2a428148d3 593 Pfam PF02653 Branched-chain amino acid transport system / permease component 35 302 2.4E-33 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_25230 5f74e52268bf0a871cf284900b7fb167 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LH59_25230 5f74e52268bf0a871cf284900b7fb167 258 Gene3D G3DSA:3.40.50.720 1 256 9.3E-78 T 14-10-2018 LH59_25230 5f74e52268bf0a871cf284900b7fb167 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 2.7E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25230 5f74e52268bf0a871cf284900b7fb167 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 2.7E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25230 5f74e52268bf0a871cf284900b7fb167 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 2.7E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25230 5f74e52268bf0a871cf284900b7fb167 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 6.6E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25230 5f74e52268bf0a871cf284900b7fb167 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 6.6E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25230 5f74e52268bf0a871cf284900b7fb167 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 6.6E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25230 5f74e52268bf0a871cf284900b7fb167 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 6.6E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25230 5f74e52268bf0a871cf284900b7fb167 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 6.6E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25230 5f74e52268bf0a871cf284900b7fb167 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 6.6E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25230 5f74e52268bf0a871cf284900b7fb167 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 252 2.8E-59 T 14-10-2018 LH59_25230 5f74e52268bf0a871cf284900b7fb167 258 SUPERFAMILY SSF51735 6 252 3.93E-78 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_14590 34189593c4dd3c37cd96f89615fbfef8 1022 Gene3D G3DSA:1.20.1640.10 500 1004 2.4E-270 T 14-10-2018 LH59_14590 34189593c4dd3c37cd96f89615fbfef8 1022 SUPERFAMILY SSF82866 288 489 2.22E-43 T 14-10-2018 LH59_14590 34189593c4dd3c37cd96f89615fbfef8 1022 SUPERFAMILY SSF82693 552 642 1.31E-10 T 14-10-2018 LH59_14590 34189593c4dd3c37cd96f89615fbfef8 1022 Gene3D G3DSA:3.30.2090.10 700 788 2.4E-270 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_14590 34189593c4dd3c37cd96f89615fbfef8 1022 PRINTS PR00702 Acriflavin resistance protein family signature 383 407 1.6E-70 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_14590 34189593c4dd3c37cd96f89615fbfef8 1022 PRINTS PR00702 Acriflavin resistance protein family signature 436 459 1.6E-70 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_14590 34189593c4dd3c37cd96f89615fbfef8 1022 PRINTS PR00702 Acriflavin resistance protein family signature 539 556 1.6E-70 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_14590 34189593c4dd3c37cd96f89615fbfef8 1022 PRINTS PR00702 Acriflavin resistance protein family signature 603 617 1.6E-70 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_14590 34189593c4dd3c37cd96f89615fbfef8 1022 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 1.6E-70 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_14590 34189593c4dd3c37cd96f89615fbfef8 1022 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 1.6E-70 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_14590 34189593c4dd3c37cd96f89615fbfef8 1022 PRINTS PR00702 Acriflavin resistance protein family signature 355 376 1.6E-70 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_14590 34189593c4dd3c37cd96f89615fbfef8 1022 PRINTS PR00702 Acriflavin resistance protein family signature 328 351 1.6E-70 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_14590 34189593c4dd3c37cd96f89615fbfef8 1022 PRINTS PR00702 Acriflavin resistance protein family signature 461 484 1.6E-70 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_14590 34189593c4dd3c37cd96f89615fbfef8 1022 Gene3D G3DSA:3.30.70.1430 554 647 2.4E-270 T 14-10-2018 LH59_14590 34189593c4dd3c37cd96f89615fbfef8 1022 Gene3D G3DSA:3.30.70.1430 38 796 2.4E-270 T 14-10-2018 LH59_14590 34189593c4dd3c37cd96f89615fbfef8 1022 Gene3D G3DSA:3.30.70.1320 133 324 2.4E-270 T 14-10-2018 LH59_14590 34189593c4dd3c37cd96f89615fbfef8 1022 SUPERFAMILY SSF82714 181 264 1.31E-13 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_14590 34189593c4dd3c37cd96f89615fbfef8 1022 Gene3D G3DSA:3.30.70.1440 649 846 2.4E-270 T 14-10-2018 LH59_14590 34189593c4dd3c37cd96f89615fbfef8 1022 SUPERFAMILY SSF82866 792 1011 3.01E-40 T 14-10-2018 LH59_14590 34189593c4dd3c37cd96f89615fbfef8 1022 Gene3D G3DSA:1.20.1640.10 8 499 2.4E-270 T 14-10-2018 LH59_14590 34189593c4dd3c37cd96f89615fbfef8 1022 Pfam PF00873 AcrB/AcrD/AcrF family 1 1007 2.9E-291 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_14590 34189593c4dd3c37cd96f89615fbfef8 1022 SUPERFAMILY SSF82693 135 322 3.4E-19 T 14-10-2018 LH59_14590 34189593c4dd3c37cd96f89615fbfef8 1022 SUPERFAMILY SSF82693 38 132 6.28E-22 T 14-10-2018 LH59_14590 34189593c4dd3c37cd96f89615fbfef8 1022 SUPERFAMILY SSF82714 702 786 3.01E-15 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_14590 34189593c4dd3c37cd96f89615fbfef8 1022 Gene3D G3DSA:3.30.2090.10 177 267 2.4E-270 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_26755 effce7bcbc289d56aa9191ce200813ec 294 Gene3D G3DSA:2.40.10.350 185 262 1.2E-31 T 14-10-2018 LH59_26755 effce7bcbc289d56aa9191ce200813ec 294 PIRSF PIRSF038471 7 288 1.3E-71 T 14-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 LH59_26755 effce7bcbc289d56aa9191ce200813ec 294 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 10 282 1.9E-55 T 14-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 LH59_26755 effce7bcbc289d56aa9191ce200813ec 294 Pfam PF04085 rod shape-determining protein MreC 128 274 2.5E-36 T 14-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 LH59_26755 effce7bcbc289d56aa9191ce200813ec 294 Gene3D G3DSA:2.40.10.340 128 271 1.2E-31 T 14-10-2018 LH59_24145 c23e4a7b5d0f0f1704e45b2a0eef428e 320 SUPERFAMILY SSF53850 156 279 8.14E-7 T 14-10-2018 LH59_24145 c23e4a7b5d0f0f1704e45b2a0eef428e 320 Gene3D G3DSA:3.40.190.10 121 244 4.9E-104 T 14-10-2018 LH59_24145 c23e4a7b5d0f0f1704e45b2a0eef428e 320 PIRSF PIRSF017082 3 319 4.8E-72 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_24145 c23e4a7b5d0f0f1704e45b2a0eef428e 320 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 43 315 3.3E-71 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_24145 c23e4a7b5d0f0f1704e45b2a0eef428e 320 Gene3D G3DSA:3.40.190.150 25 309 4.9E-104 T 14-10-2018 LH59_28050 a27c5de0941f5153ec47812d680f0372 268 Pfam PF00459 Inositol monophosphatase family 16 259 4.2E-51 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 LH59_28050 a27c5de0941f5153ec47812d680f0372 268 Gene3D G3DSA:3.40.190.80 149 264 1.2E-36 T 14-10-2018 LH59_28050 a27c5de0941f5153ec47812d680f0372 268 Gene3D G3DSA:3.30.540.10 3 147 1.4E-39 T 14-10-2018 LH59_28050 a27c5de0941f5153ec47812d680f0372 268 TIGRFAM TIGR02067 his_9_HisN: histidinol-phosphatase 16 263 5.9E-90 T 14-10-2018 IPR011809 Histidinol-phosphate phosphatase, putative, inositol monophosphatase GO:0004401 KEGG: 00340+3.1.3.15 LH59_28050 a27c5de0941f5153ec47812d680f0372 268 SUPERFAMILY SSF56655 16 264 2.88E-71 T 14-10-2018 LH59_28050 a27c5de0941f5153ec47812d680f0372 268 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 89 102 - T 14-10-2018 IPR020583 Inositol monophosphatase, metal-binding site LH59_28050 a27c5de0941f5153ec47812d680f0372 268 PRINTS PR00377 Inositol monophosphatase superfamily signature 69 85 2.2E-24 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 LH59_28050 a27c5de0941f5153ec47812d680f0372 268 PRINTS PR00377 Inositol monophosphatase superfamily signature 138 161 2.2E-24 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 LH59_28050 a27c5de0941f5153ec47812d680f0372 268 PRINTS PR00377 Inositol monophosphatase superfamily signature 181 202 2.2E-24 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 LH59_28050 a27c5de0941f5153ec47812d680f0372 268 PRINTS PR00377 Inositol monophosphatase superfamily signature 212 236 2.2E-24 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 LH59_28050 a27c5de0941f5153ec47812d680f0372 268 PRINTS PR00377 Inositol monophosphatase superfamily signature 47 67 2.2E-24 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 LH59_28050 a27c5de0941f5153ec47812d680f0372 268 PRINTS PR00377 Inositol monophosphatase superfamily signature 89 105 2.2E-24 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 LH59_27620 9b43a4e954118af9c8615eae910e9631 242 Gene3D G3DSA:3.40.50.150 24 242 9.8E-67 T 14-10-2018 LH59_27620 9b43a4e954118af9c8615eae910e9631 242 SUPERFAMILY SSF53335 6 217 3.68E-38 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_27620 9b43a4e954118af9c8615eae910e9631 242 Pfam PF08241 Methyltransferase domain 47 141 1.8E-19 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 LH59_21520 34eb4338631bbf2f630b9bdfd869f51f 352 SUPERFAMILY SSF48019 221 349 1.14E-24 T 14-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 LH59_21520 34eb4338631bbf2f630b9bdfd869f51f 352 Gene3D G3DSA:3.40.50.300 3 148 1.2E-41 T 14-10-2018 LH59_21520 34eb4338631bbf2f630b9bdfd869f51f 352 Pfam PF06144 DNA polymerase III, delta subunit 25 198 1.1E-23 T 14-10-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 LH59_21520 34eb4338631bbf2f630b9bdfd869f51f 352 Gene3D G3DSA:1.20.272.10 223 350 4.4E-23 T 14-10-2018 LH59_21520 34eb4338631bbf2f630b9bdfd869f51f 352 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 21 345 1.5E-74 T 14-10-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 LH59_21520 34eb4338631bbf2f630b9bdfd869f51f 352 Gene3D G3DSA:1.10.8.60 152 221 4.1E-26 T 14-10-2018 LH59_21520 34eb4338631bbf2f630b9bdfd869f51f 352 SUPERFAMILY SSF52540 13 219 8.5E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_11505 acc85a41dd958e2126533b786f993406 454 Gene3D G3DSA:3.30.750.140 304 420 6.7E-34 T 14-10-2018 IPR038610 FliK-like, C-terminal domain superfamily LH59_11505 acc85a41dd958e2126533b786f993406 454 Pfam PF02120 Flagellar hook-length control protein FliK 330 407 3.1E-22 T 14-10-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal LH59_11505 acc85a41dd958e2126533b786f993406 454 PRINTS PR01007 Flagellar hook-length control protein signature 359 374 2.7E-16 T 14-10-2018 IPR001635 Flagellar hook-length control protein FliK GO:0009424|GO:0044780 LH59_11505 acc85a41dd958e2126533b786f993406 454 PRINTS PR01007 Flagellar hook-length control protein signature 374 397 2.7E-16 T 14-10-2018 IPR001635 Flagellar hook-length control protein FliK GO:0009424|GO:0044780 LH59_11505 acc85a41dd958e2126533b786f993406 454 PRINTS PR01007 Flagellar hook-length control protein signature 437 453 2.7E-16 T 14-10-2018 IPR001635 Flagellar hook-length control protein FliK GO:0009424|GO:0044780 LH59_11505 acc85a41dd958e2126533b786f993406 454 PRINTS PR01007 Flagellar hook-length control protein signature 341 359 2.7E-16 T 14-10-2018 IPR001635 Flagellar hook-length control protein FliK GO:0009424|GO:0044780 LH59_11505 acc85a41dd958e2126533b786f993406 454 PRINTS PR01007 Flagellar hook-length control protein signature 69 86 2.7E-16 T 14-10-2018 IPR001635 Flagellar hook-length control protein FliK GO:0009424|GO:0044780 LH59_23445 e4de44acc7dc45e98c94973699ae34cc 300 Gene3D G3DSA:3.40.50.1820 2 293 4.8E-72 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_23445 e4de44acc7dc45e98c94973699ae34cc 300 Pfam PF12697 Alpha/beta hydrolase family 28 288 2.9E-17 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_23445 e4de44acc7dc45e98c94973699ae34cc 300 SUPERFAMILY SSF53474 4 294 8.27E-53 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_23445 e4de44acc7dc45e98c94973699ae34cc 300 PRINTS PR00412 Epoxide hydrolase signature 99 112 2.3E-17 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 LH59_23445 e4de44acc7dc45e98c94973699ae34cc 300 PRINTS PR00412 Epoxide hydrolase signature 236 252 2.3E-17 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 LH59_23445 e4de44acc7dc45e98c94973699ae34cc 300 PRINTS PR00412 Epoxide hydrolase signature 31 49 2.3E-17 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 LH59_23445 e4de44acc7dc45e98c94973699ae34cc 300 PRINTS PR00412 Epoxide hydrolase signature 51 66 2.3E-17 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 LH59_23445 e4de44acc7dc45e98c94973699ae34cc 300 PRINTS PR00412 Epoxide hydrolase signature 270 292 2.3E-17 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 LH59_03910 f4bfeb2df4a48588ade647d1d6b7d299 561 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 557 1.2E-227 T 14-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 LH59_03910 f4bfeb2df4a48588ade647d1d6b7d299 561 SUPERFAMILY SSF52016 380 558 1.1E-57 T 14-10-2018 LH59_03910 f4bfeb2df4a48588ade647d1d6b7d299 561 SUPERFAMILY SSF143975 3 378 1.96E-132 T 14-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 LH59_03910 f4bfeb2df4a48588ade647d1d6b7d299 561 Gene3D G3DSA:3.50.30.80 379 528 3.0E-52 T 14-10-2018 LH59_03910 f4bfeb2df4a48588ade647d1d6b7d299 561 Pfam PF00920 Dehydratase family 36 554 2.2E-203 T 14-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 LH59_03910 f4bfeb2df4a48588ade647d1d6b7d299 561 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 5 557 44.024 T 14-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 LH59_03910 f4bfeb2df4a48588ade647d1d6b7d299 561 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 465 476 - T 14-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 LH59_03910 f4bfeb2df4a48588ade647d1d6b7d299 561 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 123 133 - T 14-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 LH59_14180 7d463afe01a1542a1df78b660868598e 300 SUPERFAMILY SSF46785 1 75 2.54E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_14180 7d463afe01a1542a1df78b660868598e 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 34 5.3E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_14180 7d463afe01a1542a1df78b660868598e 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 13 24 5.3E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_14180 7d463afe01a1542a1df78b660868598e 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 45 5.3E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_14180 7d463afe01a1542a1df78b660868598e 300 Gene3D G3DSA:1.10.10.10 1 78 2.7E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_14180 7d463afe01a1542a1df78b660868598e 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 1 54 1.7E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_14180 7d463afe01a1542a1df78b660868598e 300 SUPERFAMILY SSF53850 80 286 4.62E-44 T 14-10-2018 LH59_14180 7d463afe01a1542a1df78b660868598e 300 Gene3D G3DSA:3.40.190.10 82 283 2.0E-63 T 14-10-2018 LH59_14180 7d463afe01a1542a1df78b660868598e 300 Gene3D G3DSA:3.40.190.10 161 259 2.0E-63 T 14-10-2018 LH59_14180 7d463afe01a1542a1df78b660868598e 300 Pfam PF03466 LysR substrate binding domain 85 288 2.2E-25 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_06535 bb249e68da8ce387ebbc35ae478a2684 358 Pfam PF03888 MucB/RseB N-terminal domain 56 229 7.5E-60 T 14-10-2018 IPR033434 MucB/RseB, N-terminal LH59_06535 bb249e68da8ce387ebbc35ae478a2684 358 Gene3D G3DSA:3.30.200.100 251 347 3.0E-15 T 14-10-2018 IPR038484 MucB/RseB, C-terminal domain superfamily LH59_06535 bb249e68da8ce387ebbc35ae478a2684 358 PIRSF PIRSF005427 19 351 8.3E-99 T 14-10-2018 IPR005588 MucB/RseB LH59_06535 bb249e68da8ce387ebbc35ae478a2684 358 Pfam PF17188 MucB/RseB C-terminal domain 249 344 8.3E-25 T 14-10-2018 IPR033436 MucB/RseB, C-terminal LH59_06535 bb249e68da8ce387ebbc35ae478a2684 358 Gene3D G3DSA:2.50.20.10 54 230 4.1E-54 T 14-10-2018 LH59_13395 01048ba2235d146bd286e282b4aa5cc1 171 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 12 159 7.3E-20 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 LH59_13395 01048ba2235d146bd286e282b4aa5cc1 171 Gene3D G3DSA:1.10.10.10 89 168 8.9E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_13395 01048ba2235d146bd286e282b4aa5cc1 171 Pfam PF08281 Sigma-70, region 4 109 157 9.2E-14 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LH59_13395 01048ba2235d146bd286e282b4aa5cc1 171 Pfam PF04542 Sigma-70 region 2 17 78 2.0E-8 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 LH59_13395 01048ba2235d146bd286e282b4aa5cc1 171 SUPERFAMILY SSF88659 91 166 2.83E-14 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like LH59_13395 01048ba2235d146bd286e282b4aa5cc1 171 SUPERFAMILY SSF88946 7 74 2.55E-10 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 LH59_21030 a33abb9f995ee383021c78fc8d3682e7 263 SMART SM00062 37 258 8.6E-39 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_21030 a33abb9f995ee383021c78fc8d3682e7 263 Gene3D G3DSA:3.40.190.10 34 248 8.1E-49 T 14-10-2018 LH59_21030 a33abb9f995ee383021c78fc8d3682e7 263 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 38 255 1.9E-38 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_21030 a33abb9f995ee383021c78fc8d3682e7 263 Gene3D G3DSA:3.40.190.10 124 216 8.1E-49 T 14-10-2018 LH59_21030 a33abb9f995ee383021c78fc8d3682e7 263 SUPERFAMILY SSF53850 11 257 1.24E-48 T 14-10-2018 LH59_22675 34ba05d7fb1773a082c64222559565aa 289 Pfam PF00005 ABC transporter 24 166 9.1E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_22675 34ba05d7fb1773a082c64222559565aa 289 Gene3D G3DSA:3.40.50.300 2 225 1.6E-59 T 14-10-2018 LH59_22675 34ba05d7fb1773a082c64222559565aa 289 TIGRFAM TIGR01184 ntrCD: nitrate ABC transporter, ATP-binding proteins C and D 24 254 1.3E-101 T 14-10-2018 IPR005890 Nitrate transport ATP-binding subunit C/D GO:0015112|GO:0015706|GO:0016020 LH59_22675 34ba05d7fb1773a082c64222559565aa 289 SMART SM00382 33 216 2.5E-18 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_22675 34ba05d7fb1773a082c64222559565aa 289 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_22675 34ba05d7fb1773a082c64222559565aa 289 SUPERFAMILY SSF52540 5 226 7.52E-66 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_18095 33faa2816d3cc33fa64831341039fbd8 267 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 86 264 1.1E-7 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 LH59_18095 33faa2816d3cc33fa64831341039fbd8 267 SUPERFAMILY SSF56529 2 266 8.9E-76 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 LH59_18095 33faa2816d3cc33fa64831341039fbd8 267 TIGRFAM TIGR02312 HpaH: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase 1 266 4.1E-133 T 14-10-2018 IPR012690 2-oxo-hepta-4-ene-1,7-dioic acid hydratase GO:0018817|GO:0019439 LH59_18095 33faa2816d3cc33fa64831341039fbd8 267 Gene3D G3DSA:3.90.850.10 1 267 3.8E-78 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 LH59_06370 795fe761c9ceed22c99399abaf6168bd 408 TIGRFAM TIGR01849 PHB_depoly_PhaZ: polyhydroxyalkanoate depolymerase, intracellular 2 406 4.2E-191 T 14-10-2018 IPR010915 Polyhydroxyalkanoate depolymerase LH59_06370 795fe761c9ceed22c99399abaf6168bd 408 Pfam PF06850 PHB de-polymerase C-terminus 206 406 7.5E-96 T 14-10-2018 IPR009656 PHB de-polymerase, C-terminal LH59_06370 795fe761c9ceed22c99399abaf6168bd 408 PIRSF PIRSF020818 1 408 1.1E-203 T 14-10-2018 IPR010915 Polyhydroxyalkanoate depolymerase LH59_06370 795fe761c9ceed22c99399abaf6168bd 408 SUPERFAMILY SSF53474 98 405 3.42E-34 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_06370 795fe761c9ceed22c99399abaf6168bd 408 Gene3D G3DSA:3.40.50.1820 93 405 2.8E-10 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_06485 d25d911a1cbda825648a36ee6364a58e 60 SUPERFAMILY SSF57829 2 55 9.16E-17 T 14-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 LH59_06485 d25d911a1cbda825648a36ee6364a58e 60 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 55 4.3E-19 T 14-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_06485 d25d911a1cbda825648a36ee6364a58e 60 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 54 16.62 T 14-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_06485 d25d911a1cbda825648a36ee6364a58e 60 Pfam PF01783 Ribosomal L32p protein family 2 55 1.1E-17 T 14-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_16515 a9759f000bf4ad2a56bbc7051aff706b 4889 Gene3D G3DSA:2.160.20.10 42 436 4.1E-95 T 14-10-2018 IPR012334 Pectin lyase fold LH59_16515 a9759f000bf4ad2a56bbc7051aff706b 4889 Pfam PF05860 haemagglutination activity domain 42 153 1.2E-24 T 14-10-2018 IPR008638 Filamentous haemagglutinin, N-terminal LH59_16515 a9759f000bf4ad2a56bbc7051aff706b 4889 SMART SM00912 40 153 2.3E-42 T 14-10-2018 IPR008638 Filamentous haemagglutinin, N-terminal LH59_16515 a9759f000bf4ad2a56bbc7051aff706b 4889 TIGRFAM TIGR01901 adhes_NPXG: filamentous hemagglutinin family N-terminal domain 75 150 4.3E-24 T 14-10-2018 IPR008638 Filamentous haemagglutinin, N-terminal LH59_16515 a9759f000bf4ad2a56bbc7051aff706b 4889 SUPERFAMILY SSF51126 45 347 2.32E-46 T 14-10-2018 IPR011050 Pectin lyase fold/virulence factor LH59_21195 2f1239731df467a118974c85f3afd40e 351 Gene3D G3DSA:3.20.20.300 3 349 9.2E-121 T 14-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 LH59_21195 2f1239731df467a118974c85f3afd40e 351 Hamap MF_00364 Beta-hexosaminidase [nagZ]. 13 350 52.631 T 14-10-2018 IPR022956 Beta-hexosaminidase, bacterial GO:0004563 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883 LH59_21195 2f1239731df467a118974c85f3afd40e 351 SUPERFAMILY SSF51445 13 328 6.11E-84 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily LH59_21195 2f1239731df467a118974c85f3afd40e 351 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 15 303 1.4E-75 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 LH59_21195 2f1239731df467a118974c85f3afd40e 351 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 247 264 - T 14-10-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 LH59_27775 adf7da8e0f706f76349c6f1efd35fae5 177 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 2.4E-72 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 LH59_27775 adf7da8e0f706f76349c6f1efd35fae5 177 Pfam PF00347 Ribosomal protein L6 90 164 8.5E-18 T 14-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27775 adf7da8e0f706f76349c6f1efd35fae5 177 Pfam PF00347 Ribosomal protein L6 12 82 5.2E-17 T 14-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27775 adf7da8e0f706f76349c6f1efd35fae5 177 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 35.712 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 LH59_27775 adf7da8e0f706f76349c6f1efd35fae5 177 Gene3D G3DSA:3.90.930.12 1 82 3.3E-27 T 14-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27775 adf7da8e0f706f76349c6f1efd35fae5 177 Gene3D G3DSA:3.90.930.12 83 177 1.6E-38 T 14-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27775 adf7da8e0f706f76349c6f1efd35fae5 177 SUPERFAMILY SSF56053 1 82 6.72E-24 T 14-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27775 adf7da8e0f706f76349c6f1efd35fae5 177 PRINTS PR00059 Ribosomal protein L6 signature 71 96 1.5E-31 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 LH59_27775 adf7da8e0f706f76349c6f1efd35fae5 177 PRINTS PR00059 Ribosomal protein L6 signature 141 162 1.5E-31 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 LH59_27775 adf7da8e0f706f76349c6f1efd35fae5 177 PRINTS PR00059 Ribosomal protein L6 signature 99 115 1.5E-31 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 LH59_27775 adf7da8e0f706f76349c6f1efd35fae5 177 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 14-10-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_27775 adf7da8e0f706f76349c6f1efd35fae5 177 PIRSF PIRSF002162 1 177 6.3E-49 T 14-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27775 adf7da8e0f706f76349c6f1efd35fae5 177 SUPERFAMILY SSF56053 83 177 1.44E-34 T 14-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_26105 93c2143cd944fd4d99b3ff6b1d816814 179 Pfam PF03079 ARD/ARD' family 19 164 9.8E-32 T 14-10-2018 IPR004313 Acireductone dioxygenase ARD family GO:0010309|GO:0055114 KEGG: 00270+1.13.11.54|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 LH59_26105 93c2143cd944fd4d99b3ff6b1d816814 179 Gene3D G3DSA:2.60.120.10 2 156 1.3E-52 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_26105 93c2143cd944fd4d99b3ff6b1d816814 179 Hamap MF_01682 Acireductone dioxygenase [mtnD]. 1 171 38.853 T 14-10-2018 IPR023956 Acireductone dioxygenase ARD, bacteria GO:0005506|GO:0010308|GO:0010309|GO:0016151|GO:0019284|GO:0055114 KEGG: 00270+1.13.11.54+1.13.11.53|MetaCyc: PWY-4361|MetaCyc: PWY-5389 LH59_26105 93c2143cd944fd4d99b3ff6b1d816814 179 SUPERFAMILY SSF51182 18 176 7.88E-41 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_21835 e2a05119f50590950ffbbb54c14358c7 367 Gene3D G3DSA:3.40.50.2000 33 361 1.8E-66 T 14-10-2018 LH59_21835 e2a05119f50590950ffbbb54c14358c7 367 Pfam PF13439 Glycosyltransferase Family 4 20 165 4.4E-12 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 LH59_21835 e2a05119f50590950ffbbb54c14358c7 367 Gene3D G3DSA:3.40.50.2000 166 348 1.8E-66 T 14-10-2018 LH59_21835 e2a05119f50590950ffbbb54c14358c7 367 SUPERFAMILY SSF53756 12 364 1.19E-71 T 14-10-2018 LH59_21835 e2a05119f50590950ffbbb54c14358c7 367 Pfam PF00534 Glycosyl transferases group 1 178 338 3.3E-34 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 LH59_12995 bf0324210b8f3f7bd2e83fe55c46938b 212 SUPERFAMILY SSF47616 83 205 6.67E-9 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily LH59_12995 bf0324210b8f3f7bd2e83fe55c46938b 212 Gene3D G3DSA:3.40.30.10 9 203 3.9E-37 T 14-10-2018 LH59_12995 bf0324210b8f3f7bd2e83fe55c46938b 212 Pfam PF13409 Glutathione S-transferase, N-terminal domain 17 75 4.9E-9 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 LH59_12995 bf0324210b8f3f7bd2e83fe55c46938b 212 Gene3D G3DSA:1.20.1050.10 85 196 3.9E-37 T 14-10-2018 LH59_12995 bf0324210b8f3f7bd2e83fe55c46938b 212 SUPERFAMILY SSF52833 3 87 4.3E-15 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_16830 dcdb9f1f2f7eb7639acf48530fb72377 540 PRINTS PR00298 60kDa chaperonin signature 350 375 8.2E-75 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 LH59_16830 dcdb9f1f2f7eb7639acf48530fb72377 540 PRINTS PR00298 60kDa chaperonin signature 398 419 8.2E-75 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 LH59_16830 dcdb9f1f2f7eb7639acf48530fb72377 540 PRINTS PR00298 60kDa chaperonin signature 268 291 8.2E-75 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 LH59_16830 dcdb9f1f2f7eb7639acf48530fb72377 540 PRINTS PR00298 60kDa chaperonin signature 27 53 8.2E-75 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 LH59_16830 dcdb9f1f2f7eb7639acf48530fb72377 540 PRINTS PR00298 60kDa chaperonin signature 83 110 8.2E-75 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 LH59_16830 dcdb9f1f2f7eb7639acf48530fb72377 540 Hamap MF_00600 60 kDa chaperonin [groL]. 2 538 40.783 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 LH59_16830 dcdb9f1f2f7eb7639acf48530fb72377 540 SUPERFAMILY SSF54849 137 203 3.2E-24 T 14-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily LH59_16830 dcdb9f1f2f7eb7639acf48530fb72377 540 SUPERFAMILY SSF52029 184 376 1.2E-81 T 14-10-2018 IPR027409 GroEL-like apical domain superfamily LH59_16830 dcdb9f1f2f7eb7639acf48530fb72377 540 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 522 7.7E-98 T 14-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 LH59_16830 dcdb9f1f2f7eb7639acf48530fb72377 540 Gene3D G3DSA:3.30.260.10 136 410 1.4E-237 T 14-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily LH59_16830 dcdb9f1f2f7eb7639acf48530fb72377 540 SUPERFAMILY SSF48592 7 521 5.73E-77 T 14-10-2018 IPR027413 GroEL-like equatorial domain superfamily LH59_16830 dcdb9f1f2f7eb7639acf48530fb72377 540 Gene3D G3DSA:3.50.7.10 192 372 1.4E-237 T 14-10-2018 IPR027409 GroEL-like apical domain superfamily LH59_16830 dcdb9f1f2f7eb7639acf48530fb72377 540 Gene3D G3DSA:1.10.560.10 8 521 1.4E-237 T 14-10-2018 IPR027413 GroEL-like equatorial domain superfamily LH59_16830 dcdb9f1f2f7eb7639acf48530fb72377 540 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 14-10-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 LH59_16830 dcdb9f1f2f7eb7639acf48530fb72377 540 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 526 3.2E-253 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 LH59_20080 ff388bf467a650f1f15082f2280fecc2 198 Gene3D G3DSA:3.50.70.10 32 180 4.6E-18 T 14-10-2018 IPR016088 Chalcone isomerase, 3-layer sandwich KEGG: 00941+5.5.1.6|MetaCyc: PWY-2002|MetaCyc: PWY-5059|MetaCyc: PWY-6325|MetaCyc: PWY-6787|MetaCyc: PWY-7397|MetaCyc: PWY-7897 LH59_20080 ff388bf467a650f1f15082f2280fecc2 198 Pfam PF16036 Chalcone isomerase-like 31 196 1.2E-47 T 14-10-2018 IPR016087 Chalcone isomerase GO:0016872 LH59_20080 ff388bf467a650f1f15082f2280fecc2 198 SUPERFAMILY SSF54626 31 195 1.27E-19 T 14-10-2018 IPR036298 Chalcone isomerase superfamily GO:0016872 LH59_25235 1fb0606cf1d8487661eaefd028a59cf3 304 Gene3D G3DSA:3.20.20.70 3 294 5.6E-91 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_25235 1fb0606cf1d8487661eaefd028a59cf3 304 Pfam PF05853 beta-keto acid cleavage enzyme 5 292 3.3E-88 T 14-10-2018 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00310+2.3.1.247 LH59_09330 ce067b6d5edad7c9b3e86540688f025a 437 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 35 286 6.0E-72 T 14-10-2018 IPR017039 Virulence factor BrkB LH59_09330 ce067b6d5edad7c9b3e86540688f025a 437 Pfam PF03631 Virulence factor BrkB 41 286 1.8E-57 T 14-10-2018 IPR017039 Virulence factor BrkB LH59_09330 ce067b6d5edad7c9b3e86540688f025a 437 Hamap MF_00672 UPF0761 membrane protein YihY [yihY]. 26 318 22.779 T 14-10-2018 IPR023679 Uncharacterised protein family UPF0761, bacterial LH59_17030 387df05e9728bd06c2c63362ab5e3242 673 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 54 - T 14-10-2018 IPR010916 TonB box, conserved site LH59_17030 387df05e9728bd06c2c63362ab5e3242 673 Pfam PF00593 TonB dependent receptor 209 672 9.4E-65 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_17030 387df05e9728bd06c2c63362ab5e3242 673 Pfam PF07715 TonB-dependent Receptor Plug Domain 61 170 3.5E-27 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_17030 387df05e9728bd06c2c63362ab5e3242 673 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 656 673 - T 14-10-2018 IPR010917 TonB-dependent receptor, conserved site LH59_17030 387df05e9728bd06c2c63362ab5e3242 673 Gene3D G3DSA:2.170.130.10 42 175 4.9E-41 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily LH59_17030 387df05e9728bd06c2c63362ab5e3242 673 Gene3D G3DSA:2.40.170.20 181 673 9.3E-149 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_17030 387df05e9728bd06c2c63362ab5e3242 673 SUPERFAMILY SSF56935 37 673 3.66E-133 T 14-10-2018 LH59_21675 f161f357bf54bfbdc02a01c915305468 489 Gene3D G3DSA:3.30.450.20 151 253 1.8E-21 T 14-10-2018 LH59_21675 f161f357bf54bfbdc02a01c915305468 489 SUPERFAMILY SSF55785 32 133 1.12E-27 T 14-10-2018 IPR035965 PAS domain superfamily LH59_21675 f161f357bf54bfbdc02a01c915305468 489 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 153 264 3.4E-19 T 14-10-2018 IPR000014 PAS domain LH59_21675 f161f357bf54bfbdc02a01c915305468 489 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 29 141 4.3E-19 T 14-10-2018 IPR000014 PAS domain LH59_21675 f161f357bf54bfbdc02a01c915305468 489 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 400 429 1.2E-32 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_21675 f161f357bf54bfbdc02a01c915305468 489 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 352 381 1.2E-32 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_21675 f161f357bf54bfbdc02a01c915305468 489 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 323 350 1.2E-32 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_21675 f161f357bf54bfbdc02a01c915305468 489 SMART SM00091 141 210 9.6 T 14-10-2018 IPR000014 PAS domain LH59_21675 f161f357bf54bfbdc02a01c915305468 489 SMART SM00091 21 89 0.0056 T 14-10-2018 IPR000014 PAS domain LH59_21675 f161f357bf54bfbdc02a01c915305468 489 SMART SM00086 94 136 8.1E-5 T 14-10-2018 IPR001610 PAC motif LH59_21675 f161f357bf54bfbdc02a01c915305468 489 SMART SM00086 216 258 1.0E-4 T 14-10-2018 IPR001610 PAC motif LH59_21675 f161f357bf54bfbdc02a01c915305468 489 Pfam PF08447 PAS fold 166 251 1.3E-14 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 LH59_21675 f161f357bf54bfbdc02a01c915305468 489 Pfam PF08447 PAS fold 44 129 1.6E-15 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 LH59_21675 f161f357bf54bfbdc02a01c915305468 489 SUPERFAMILY SSF55785 155 255 6.11E-25 T 14-10-2018 IPR035965 PAS domain superfamily LH59_21675 f161f357bf54bfbdc02a01c915305468 489 SUPERFAMILY SSF58104 264 459 6.15E-47 T 14-10-2018 LH59_21675 f161f357bf54bfbdc02a01c915305468 489 Gene3D G3DSA:3.30.450.20 16 150 3.5E-25 T 14-10-2018 LH59_21675 f161f357bf54bfbdc02a01c915305468 489 Gene3D G3DSA:1.10.287.950 254 462 1.9E-48 T 14-10-2018 LH59_21675 f161f357bf54bfbdc02a01c915305468 489 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 285 438 2.2E-44 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 LH59_21675 f161f357bf54bfbdc02a01c915305468 489 SMART SM00283 247 465 2.1E-41 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 LH59_26995 a5f835faa5d4333cbf5e53d7c35b2a48 253 SUPERFAMILY SSF52141 19 240 4.14E-74 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 LH59_26995 a5f835faa5d4333cbf5e53d7c35b2a48 253 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 71 80 - T 14-10-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 LH59_26995 a5f835faa5d4333cbf5e53d7c35b2a48 253 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 20 239 34.561 T 14-10-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 LH59_26995 a5f835faa5d4333cbf5e53d7c35b2a48 253 SMART SM00987 63 228 2.6E-32 T 14-10-2018 LH59_26995 a5f835faa5d4333cbf5e53d7c35b2a48 253 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 22 232 2.0E-69 T 14-10-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 LH59_26995 a5f835faa5d4333cbf5e53d7c35b2a48 253 SMART SM00986 63 228 2.6E-32 T 14-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 LH59_26995 a5f835faa5d4333cbf5e53d7c35b2a48 253 Pfam PF03167 Uracil DNA glycosylase superfamily 64 227 2.5E-22 T 14-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 LH59_26995 a5f835faa5d4333cbf5e53d7c35b2a48 253 Gene3D G3DSA:3.40.470.10 4 246 2.0E-81 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 LH59_00615 c983823a3878d4b4ce94ee3cf8ff09d7 397 Gene3D G3DSA:3.90.1150.10 263 396 6.0E-35 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_00615 c983823a3878d4b4ce94ee3cf8ff09d7 397 Gene3D G3DSA:3.40.640.10 1 260 1.6E-67 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_00615 c983823a3878d4b4ce94ee3cf8ff09d7 397 SUPERFAMILY SSF53383 44 391 1.67E-90 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_00615 c983823a3878d4b4ce94ee3cf8ff09d7 397 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 203 217 - T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 LH59_00615 c983823a3878d4b4ce94ee3cf8ff09d7 397 PIRSF PIRSF001434 1 393 6.8E-117 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 LH59_00615 c983823a3878d4b4ce94ee3cf8ff09d7 397 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 8 390 1.4E-93 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 LH59_00615 c983823a3878d4b4ce94ee3cf8ff09d7 397 TIGRFAM TIGR01324 cysta_beta_ly_B: cystathionine beta-lyase 8 391 1.5E-111 T 14-10-2018 IPR006233 Cystathionine beta-lyase, bacterial GO:0004121|GO:0005737|GO:0006520 KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8 LH59_00735 bbe9a726a33ebec863c4015a82b0f5c9 158 PIRSF PIRSF002560 1 157 1.9E-73 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 LH59_00735 bbe9a726a33ebec863c4015a82b0f5c9 158 Gene3D G3DSA:1.20.1260.10 1 156 3.4E-70 T 14-10-2018 IPR012347 Ferritin-like LH59_00735 bbe9a726a33ebec863c4015a82b0f5c9 158 Pfam PF00210 Ferritin-like domain 9 143 2.3E-39 T 14-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 LH59_00735 bbe9a726a33ebec863c4015a82b0f5c9 158 TIGRFAM TIGR00754 bfr: bacterioferritin 1 155 8.5E-76 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 LH59_00735 bbe9a726a33ebec863c4015a82b0f5c9 158 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 LH59_00735 bbe9a726a33ebec863c4015a82b0f5c9 158 SUPERFAMILY SSF47240 1 154 4.28E-54 T 14-10-2018 IPR009078 Ferritin-like superfamily LH59_00735 bbe9a726a33ebec863c4015a82b0f5c9 158 PRINTS PR00601 Bacterioferritin signature 44 64 1.5E-67 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 LH59_00735 bbe9a726a33ebec863c4015a82b0f5c9 158 PRINTS PR00601 Bacterioferritin signature 86 106 1.5E-67 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 LH59_00735 bbe9a726a33ebec863c4015a82b0f5c9 158 PRINTS PR00601 Bacterioferritin signature 3 22 1.5E-67 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 LH59_00735 bbe9a726a33ebec863c4015a82b0f5c9 158 PRINTS PR00601 Bacterioferritin signature 128 149 1.5E-67 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 LH59_00735 bbe9a726a33ebec863c4015a82b0f5c9 158 PRINTS PR00601 Bacterioferritin signature 23 43 1.5E-67 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 LH59_00735 bbe9a726a33ebec863c4015a82b0f5c9 158 PRINTS PR00601 Bacterioferritin signature 65 85 1.5E-67 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 LH59_00735 bbe9a726a33ebec863c4015a82b0f5c9 158 PRINTS PR00601 Bacterioferritin signature 107 127 1.5E-67 T 14-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 LH59_11580 237724f15ef3d9e68af48a168c76baaf 388 Gene3D G3DSA:2.40.110.10 122 238 6.3E-33 T 14-10-2018 LH59_11580 237724f15ef3d9e68af48a168c76baaf 388 Gene3D G3DSA:1.20.140.10 239 386 1.8E-42 T 14-10-2018 LH59_11580 237724f15ef3d9e68af48a168c76baaf 388 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 233 365 7.0E-39 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LH59_11580 237724f15ef3d9e68af48a168c76baaf 388 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 6.7E-26 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 LH59_11580 237724f15ef3d9e68af48a168c76baaf 388 SUPERFAMILY SSF47203 231 386 4.03E-48 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 LH59_11580 237724f15ef3d9e68af48a168c76baaf 388 SUPERFAMILY SSF56645 1 246 3.53E-66 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 LH59_11580 237724f15ef3d9e68af48a168c76baaf 388 Gene3D G3DSA:1.10.540.10 1 120 5.3E-33 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 LH59_11580 237724f15ef3d9e68af48a168c76baaf 388 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 219 5.3E-21 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 LH59_11580 237724f15ef3d9e68af48a168c76baaf 388 PIRSF PIRSF016578 139 191 31.0 T 14-10-2018 LH59_11580 237724f15ef3d9e68af48a168c76baaf 388 PIRSF PIRSF016578 25 99 0.035 T 14-10-2018 LH59_11580 237724f15ef3d9e68af48a168c76baaf 388 PIRSF PIRSF016578 242 385 2.5E-10 T 14-10-2018 LH59_20420 568f623c3dd7489ecfe454151057afd9 282 SUPERFAMILY SSF82689 173 269 4.84E-22 T 14-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 LH59_20420 568f623c3dd7489ecfe454151057afd9 282 SUPERFAMILY SSF50182 106 172 5.89E-15 T 14-10-2018 IPR010920 LSM domain superfamily LH59_20420 568f623c3dd7489ecfe454151057afd9 282 Pfam PF05552 Conserved TM helix 13 50 2.4E-7 T 14-10-2018 IPR008910 Conserved TM helix LH59_20420 568f623c3dd7489ecfe454151057afd9 282 Gene3D G3DSA:2.30.30.60 121 171 2.2E-13 T 14-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily LH59_20420 568f623c3dd7489ecfe454151057afd9 282 Gene3D G3DSA:3.30.70.100 172 265 1.2E-16 T 14-10-2018 LH59_20420 568f623c3dd7489ecfe454151057afd9 282 Pfam PF00924 Mechanosensitive ion channel 69 257 5.2E-45 T 14-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 LH59_20420 568f623c3dd7489ecfe454151057afd9 282 SUPERFAMILY SSF82861 19 104 3.79E-18 T 14-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 LH59_09240 963e2d2e101d51e4b56c9fab5f31c473 757 Pfam PF04539 Sigma-70 region 3 601 676 3.1E-24 T 14-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 LH59_09240 963e2d2e101d51e4b56c9fab5f31c473 757 Pfam PF03979 Sigma-70 factor, region 1.1 152 231 6.4E-29 T 14-10-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 LH59_09240 963e2d2e101d51e4b56c9fab5f31c473 757 Pfam PF00140 Sigma-70 factor, region 1.2 250 282 4.7E-14 T 14-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LH59_09240 963e2d2e101d51e4b56c9fab5f31c473 757 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 546 559 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 LH59_09240 963e2d2e101d51e4b56c9fab5f31c473 757 SUPERFAMILY SSF88946 267 589 2.04E-96 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 LH59_09240 963e2d2e101d51e4b56c9fab5f31c473 757 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 152 755 42.018 T 14-10-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 LH59_09240 963e2d2e101d51e4b56c9fab5f31c473 757 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 518 743 3.3E-39 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 LH59_09240 963e2d2e101d51e4b56c9fab5f31c473 757 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 518 754 1.8E-118 T 14-10-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 LH59_09240 963e2d2e101d51e4b56c9fab5f31c473 757 SUPERFAMILY SSF88659 595 668 2.04E-18 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like LH59_09240 963e2d2e101d51e4b56c9fab5f31c473 757 PRINTS PR00046 Major sigma-70 factor signature 546 559 7.8E-31 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 LH59_09240 963e2d2e101d51e4b56c9fab5f31c473 757 PRINTS PR00046 Major sigma-70 factor signature 715 730 7.8E-31 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 LH59_09240 963e2d2e101d51e4b56c9fab5f31c473 757 PRINTS PR00046 Major sigma-70 factor signature 694 706 7.8E-31 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 LH59_09240 963e2d2e101d51e4b56c9fab5f31c473 757 PRINTS PR00046 Major sigma-70 factor signature 730 741 7.8E-31 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 LH59_09240 963e2d2e101d51e4b56c9fab5f31c473 757 PRINTS PR00046 Major sigma-70 factor signature 570 578 7.8E-31 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 LH59_09240 963e2d2e101d51e4b56c9fab5f31c473 757 Gene3D G3DSA:1.10.601.10 265 591 1.1E-124 T 14-10-2018 LH59_09240 963e2d2e101d51e4b56c9fab5f31c473 757 SUPERFAMILY SSF88659 652 753 6.35E-27 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like LH59_09240 963e2d2e101d51e4b56c9fab5f31c473 757 Pfam PF04546 Sigma-70, non-essential region 291 491 5.0E-62 T 14-10-2018 IPR007631 RNA polymerase sigma factor 70, non-essential domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LH59_09240 963e2d2e101d51e4b56c9fab5f31c473 757 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 715 741 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 LH59_09240 963e2d2e101d51e4b56c9fab5f31c473 757 Gene3D G3DSA:1.10.10.10 595 670 1.5E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_09240 963e2d2e101d51e4b56c9fab5f31c473 757 Gene3D G3DSA:1.10.220.120 150 212 2.2E-27 T 14-10-2018 LH59_09240 963e2d2e101d51e4b56c9fab5f31c473 757 Pfam PF04542 Sigma-70 region 2 524 591 8.6E-21 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 LH59_09240 963e2d2e101d51e4b56c9fab5f31c473 757 Pfam PF04545 Sigma-70, region 4 690 743 7.7E-19 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 LH59_09240 963e2d2e101d51e4b56c9fab5f31c473 757 Gene3D G3DSA:1.10.10.10 672 756 5.3E-35 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_27100 594d32f19cd5200ebca54976f61cafff 336 SUPERFAMILY SSF46785 181 232 9.67E-7 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_27100 594d32f19cd5200ebca54976f61cafff 336 SMART SM00344 16 121 3.4E-10 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 LH59_27100 594d32f19cd5200ebca54976f61cafff 336 SMART SM00344 182 287 9.4E-5 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 LH59_27100 594d32f19cd5200ebca54976f61cafff 336 Pfam PF13404 AsnC-type helix-turn-helix domain 16 56 3.3E-13 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_27100 594d32f19cd5200ebca54976f61cafff 336 Gene3D G3DSA:1.10.10.10 14 65 1.7E-12 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_27100 594d32f19cd5200ebca54976f61cafff 336 Gene3D G3DSA:3.30.70.920 68 161 1.4E-9 T 14-10-2018 LH59_27100 594d32f19cd5200ebca54976f61cafff 336 Gene3D G3DSA:3.30.70.920 234 322 1.7E-8 T 14-10-2018 LH59_27100 594d32f19cd5200ebca54976f61cafff 336 Gene3D G3DSA:1.10.10.10 184 231 2.5E-7 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_27100 594d32f19cd5200ebca54976f61cafff 336 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 43 5.7E-6 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_27100 594d32f19cd5200ebca54976f61cafff 336 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 43 62 5.7E-6 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_27100 594d32f19cd5200ebca54976f61cafff 336 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 16 32 5.7E-6 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_27100 594d32f19cd5200ebca54976f61cafff 336 Pfam PF09339 IclR helix-turn-helix domain 189 228 9.0E-8 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_27100 594d32f19cd5200ebca54976f61cafff 336 SUPERFAMILY SSF54909 77 152 2.01E-8 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel LH59_27100 594d32f19cd5200ebca54976f61cafff 336 SUPERFAMILY SSF46785 15 66 2.99E-7 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_27100 594d32f19cd5200ebca54976f61cafff 336 SUPERFAMILY SSF54909 241 318 7.78E-8 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel LH59_10085 da7f8951eb24242cebdfac7de376d73e 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 65 3.6E-19 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_10085 da7f8951eb24242cebdfac7de376d73e 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 2.2E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_10085 da7f8951eb24242cebdfac7de376d73e 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 2.2E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_10085 da7f8951eb24242cebdfac7de376d73e 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 2.2E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_10085 da7f8951eb24242cebdfac7de376d73e 293 Pfam PF03466 LysR substrate binding domain 90 292 2.5E-27 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_10085 da7f8951eb24242cebdfac7de376d73e 293 SUPERFAMILY SSF53850 82 293 3.26E-31 T 14-10-2018 LH59_10085 da7f8951eb24242cebdfac7de376d73e 293 Gene3D G3DSA:3.40.190.10 163 260 1.9E-38 T 14-10-2018 LH59_10085 da7f8951eb24242cebdfac7de376d73e 293 SUPERFAMILY SSF46785 7 113 4.81E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_10085 da7f8951eb24242cebdfac7de376d73e 293 Gene3D G3DSA:3.40.190.10 102 288 1.9E-38 T 14-10-2018 LH59_10085 da7f8951eb24242cebdfac7de376d73e 293 Gene3D G3DSA:1.10.10.10 5 92 2.5E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_12330 7477f3be6fa3e96a6ef251e74cf80f6b 340 SUPERFAMILY SSF51679 7 327 1.7E-82 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 LH59_12330 7477f3be6fa3e96a6ef251e74cf80f6b 340 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 9 327 5.6E-131 T 14-10-2018 IPR019949 Luciferase family oxidoreductase, group 1 LH59_12330 7477f3be6fa3e96a6ef251e74cf80f6b 340 Pfam PF00296 Luciferase-like monooxygenase 20 303 4.7E-39 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LH59_12330 7477f3be6fa3e96a6ef251e74cf80f6b 340 Gene3D G3DSA:3.20.20.30 4 331 2.7E-98 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 LH59_12495 e930a669b257bca2185a2a590663d15f 348 SUPERFAMILY SSF53850 131 268 2.54E-6 T 14-10-2018 LH59_12495 e930a669b257bca2185a2a590663d15f 348 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 48 278 1.7E-29 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 LH59_12495 e930a669b257bca2185a2a590663d15f 348 Gene3D G3DSA:3.40.190.170 27 340 1.2E-67 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily LH59_26080 b3a11a38ba5022aeccc0f9c7c949e297 267 SUPERFAMILY SSF55781 75 245 6.28E-30 T 14-10-2018 LH59_26080 b3a11a38ba5022aeccc0f9c7c949e297 267 Pfam PF01614 Bacterial transcriptional regulator 133 244 5.1E-11 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal LH59_26080 b3a11a38ba5022aeccc0f9c7c949e297 267 Gene3D G3DSA:1.10.10.10 12 73 3.2E-12 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_26080 b3a11a38ba5022aeccc0f9c7c949e297 267 Pfam PF09339 IclR helix-turn-helix domain 14 61 7.7E-12 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_26080 b3a11a38ba5022aeccc0f9c7c949e297 267 SUPERFAMILY SSF46785 14 74 8.56E-10 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_26080 b3a11a38ba5022aeccc0f9c7c949e297 267 SMART SM00346 11 100 0.0031 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_26080 b3a11a38ba5022aeccc0f9c7c949e297 267 Gene3D G3DSA:3.30.450.40 83 252 7.8E-27 T 14-10-2018 IPR029016 GAF-like domain superfamily LH59_01640 c16c9a70e2fc2a727d38924749eff5b3 390 Pfam PF00296 Luciferase-like monooxygenase 1 334 9.9E-85 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LH59_01640 c16c9a70e2fc2a727d38924749eff5b3 390 Hamap MF_01229 Alkanesulfonate monooxygenase [ssuD]. 1 388 77.279 T 14-10-2018 IPR019911 Alkanesulphonate monooxygenase, FMN-dependent GO:0008726|GO:0055114 KEGG: 00920+1.14.14.5 LH59_01640 c16c9a70e2fc2a727d38924749eff5b3 390 Gene3D G3DSA:3.20.20.30 1 365 3.1E-136 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 LH59_01640 c16c9a70e2fc2a727d38924749eff5b3 390 TIGRFAM TIGR03565 alk_sulf_monoox: alkanesulfonate monooxygenase, FMNH(2)-dependent 2 358 3.1E-183 T 14-10-2018 IPR019911 Alkanesulphonate monooxygenase, FMN-dependent GO:0008726|GO:0055114 KEGG: 00920+1.14.14.5 LH59_01640 c16c9a70e2fc2a727d38924749eff5b3 390 SUPERFAMILY SSF51679 1 359 6.8E-91 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 LH59_05260 1e6c706cde8eedff071c335e6e3f73b5 345 SUPERFAMILY SSF56176 17 204 3.07E-34 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 LH59_05260 1e6c706cde8eedff071c335e6e3f73b5 345 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 222 345 6.6E-37 T 14-10-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 LH59_05260 1e6c706cde8eedff071c335e6e3f73b5 345 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 345 82.716 T 14-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 LH59_05260 1e6c706cde8eedff071c335e6e3f73b5 345 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 22 341 3.7E-64 T 14-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 LH59_05260 1e6c706cde8eedff071c335e6e3f73b5 345 Gene3D G3DSA:3.30.43.10 14 79 1.2E-9 T 14-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 LH59_05260 1e6c706cde8eedff071c335e6e3f73b5 345 Gene3D G3DSA:3.30.465.10 82 234 4.1E-54 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 LH59_05260 1e6c706cde8eedff071c335e6e3f73b5 345 Gene3D G3DSA:3.90.78.10 235 345 2.7E-44 T 14-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 LH59_05260 1e6c706cde8eedff071c335e6e3f73b5 345 Pfam PF01565 FAD binding domain 31 162 1.6E-17 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 LH59_05260 1e6c706cde8eedff071c335e6e3f73b5 345 SUPERFAMILY SSF56194 218 345 4.32E-49 T 14-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 LH59_27190 334e682e2ac2d358b654398cf40fc9f5 179 Pfam PF00227 Proteasome subunit 5 175 2.0E-21 T 14-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 LH59_27190 334e682e2ac2d358b654398cf40fc9f5 179 PIRSF PIRSF039093 1 179 1.7E-85 T 14-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 LH59_27190 334e682e2ac2d358b654398cf40fc9f5 179 Gene3D G3DSA:3.60.20.10 2 178 8.6E-66 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal LH59_27190 334e682e2ac2d358b654398cf40fc9f5 179 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 7 177 3.6E-84 T 14-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 LH59_27190 334e682e2ac2d358b654398cf40fc9f5 179 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 6 177 40.934 T 14-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 LH59_27190 334e682e2ac2d358b654398cf40fc9f5 179 SUPERFAMILY SSF56235 3 177 3.05E-58 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal LH59_00680 7cdf82f087466fe3dd6a7ccb6bcc27a0 337 Gene3D G3DSA:3.40.50.2300 69 320 7.7E-71 T 14-10-2018 LH59_00680 7cdf82f087466fe3dd6a7ccb6bcc27a0 337 Gene3D G3DSA:3.40.50.2300 166 294 7.7E-71 T 14-10-2018 LH59_00680 7cdf82f087466fe3dd6a7ccb6bcc27a0 337 SUPERFAMILY SSF47413 8 66 5.25E-14 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 LH59_00680 7cdf82f087466fe3dd6a7ccb6bcc27a0 337 Pfam PF13377 Periplasmic binding protein-like domain 174 331 7.8E-33 T 14-10-2018 LH59_00680 7cdf82f087466fe3dd6a7ccb6bcc27a0 337 Pfam PF00356 Bacterial regulatory proteins, lacI family 11 55 7.6E-11 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 LH59_00680 7cdf82f087466fe3dd6a7ccb6bcc27a0 337 SMART SM00354 8 78 1.7E-22 T 14-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 LH59_00680 7cdf82f087466fe3dd6a7ccb6bcc27a0 337 SUPERFAMILY SSF53822 66 319 6.13E-66 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_00680 7cdf82f087466fe3dd6a7ccb6bcc27a0 337 Gene3D G3DSA:1.10.260.40 2 66 1.9E-17 T 14-10-2018 LH59_11405 2fcc22ec1295074ed849d1efda22c1fe 231 Gene3D G3DSA:2.60.40.4070 102 196 1.8E-32 T 14-10-2018 LH59_11405 2fcc22ec1295074ed849d1efda22c1fe 231 Pfam PF03963 Flagellar hook capping protein - N-terminal region 6 75 8.7E-22 T 14-10-2018 IPR005648 Flagellar hook capping protein LH59_11405 2fcc22ec1295074ed849d1efda22c1fe 231 Pfam PF13861 FlgD Tudor-like domain 85 227 2.2E-14 T 14-10-2018 IPR025963 FlgD Tudor-like domain LH59_11405 2fcc22ec1295074ed849d1efda22c1fe 231 Pfam PF13860 FlgD Ig-like domain 120 186 2.5E-22 T 14-10-2018 IPR025965 FlgD Ig-like domain LH59_11405 2fcc22ec1295074ed849d1efda22c1fe 231 Gene3D G3DSA:2.30.30.910 86 223 1.8E-32 T 14-10-2018 LH59_03905 0ecb7a34809b8dc43bcef37ca088b6e1 262 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 6 260 20.525 T 14-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 LH59_03905 0ecb7a34809b8dc43bcef37ca088b6e1 262 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 3 260 1.4E-82 T 14-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 LH59_03905 0ecb7a34809b8dc43bcef37ca088b6e1 262 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 139 151 - T 14-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 LH59_03905 0ecb7a34809b8dc43bcef37ca088b6e1 262 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 9 254 4.9E-84 T 14-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 LH59_26380 f16f41f67e0206bf01b842ab8bba64aa 89 SUPERFAMILY SSF52833 1 86 5.46E-30 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_26380 f16f41f67e0206bf01b842ab8bba64aa 89 PRINTS PR00160 Glutaredoxin signature 4 22 2.8E-19 T 14-10-2018 IPR014025 Glutaredoxin subgroup LH59_26380 f16f41f67e0206bf01b842ab8bba64aa 89 PRINTS PR00160 Glutaredoxin signature 61 74 2.8E-19 T 14-10-2018 IPR014025 Glutaredoxin subgroup LH59_26380 f16f41f67e0206bf01b842ab8bba64aa 89 PRINTS PR00160 Glutaredoxin signature 47 60 2.8E-19 T 14-10-2018 IPR014025 Glutaredoxin subgroup LH59_26380 f16f41f67e0206bf01b842ab8bba64aa 89 Pfam PF00462 Glutaredoxin 4 64 5.3E-22 T 14-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 LH59_26380 f16f41f67e0206bf01b842ab8bba64aa 89 ProSitePatterns PS00195 Glutaredoxin active site. 6 22 - T 14-10-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 LH59_26380 f16f41f67e0206bf01b842ab8bba64aa 89 TIGRFAM TIGR02181 GRX_bact: glutaredoxin 3 4 83 6.4E-35 T 14-10-2018 IPR011900 Glutaredoxin, GrxC GO:0045454 LH59_26380 f16f41f67e0206bf01b842ab8bba64aa 89 Gene3D G3DSA:3.40.30.10 1 87 2.3E-29 T 14-10-2018 LH59_00035 a02a9a75e342ae21c2c348f7d3dccd12 234 PIRSF PIRSF006232 1 234 1.9E-44 T 14-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 LH59_00035 a02a9a75e342ae21c2c348f7d3dccd12 234 Gene3D G3DSA:2.60.120.10 11 134 2.1E-71 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_00035 a02a9a75e342ae21c2c348f7d3dccd12 234 SUPERFAMILY SSF51182 1 231 1.47E-62 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_00035 a02a9a75e342ae21c2c348f7d3dccd12 234 Gene3D G3DSA:2.60.120.10 10 231 2.1E-71 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_00035 a02a9a75e342ae21c2c348f7d3dccd12 234 Pfam PF02678 Pirin 15 118 2.3E-27 T 14-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 LH59_24740 9698bed8d69d074690361adbaf94f35b 323 Pfam PF00303 Thymidylate synthase 2 323 5.6E-86 T 14-10-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 LH59_24740 9698bed8d69d074690361adbaf94f35b 323 Hamap MF_00008 Thymidylate synthase [thyA]. 1 323 35.09 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 LH59_24740 9698bed8d69d074690361adbaf94f35b 323 ProSitePatterns PS00091 Thymidylate synthase active site. 172 199 - T 14-10-2018 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 LH59_24740 9698bed8d69d074690361adbaf94f35b 323 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 2 323 2.9E-58 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 LH59_24740 9698bed8d69d074690361adbaf94f35b 323 SUPERFAMILY SSF55831 1 323 2.75E-96 T 14-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 LH59_24740 9698bed8d69d074690361adbaf94f35b 323 Gene3D G3DSA:3.30.572.10 1 323 1.3E-121 T 14-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 LH59_24740 9698bed8d69d074690361adbaf94f35b 323 PRINTS PR00108 Thymidylate synthase family signature 187 202 2.5E-28 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 LH59_24740 9698bed8d69d074690361adbaf94f35b 323 PRINTS PR00108 Thymidylate synthase family signature 42 63 2.5E-28 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 LH59_24740 9698bed8d69d074690361adbaf94f35b 323 PRINTS PR00108 Thymidylate synthase family signature 245 262 2.5E-28 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 LH59_24740 9698bed8d69d074690361adbaf94f35b 323 PRINTS PR00108 Thymidylate synthase family signature 207 233 2.5E-28 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 LH59_24740 9698bed8d69d074690361adbaf94f35b 323 PRINTS PR00108 Thymidylate synthase family signature 161 180 2.5E-28 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 LH59_12550 0bcd1cb766eb239b77705a2216ca2d0f 235 Gene3D G3DSA:3.40.50.300 1 235 8.0E-63 T 14-10-2018 LH59_12550 0bcd1cb766eb239b77705a2216ca2d0f 235 SUPERFAMILY SSF52540 2 233 1.15E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_12550 0bcd1cb766eb239b77705a2216ca2d0f 235 SMART SM00382 26 214 8.2E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_12550 0bcd1cb766eb239b77705a2216ca2d0f 235 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_12550 0bcd1cb766eb239b77705a2216ca2d0f 235 Pfam PF00005 ABC transporter 18 162 1.6E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_04920 2d515ad131253f451fff3b6d79908ebb 262 SUPERFAMILY SSF46689 210 257 4.08E-7 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_04920 2d515ad131253f451fff3b6d79908ebb 262 SUPERFAMILY SSF51182 17 88 1.8E-11 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_04920 2d515ad131253f451fff3b6d79908ebb 262 Gene3D G3DSA:1.10.10.60 155 261 1.1E-18 T 14-10-2018 LH59_04920 2d515ad131253f451fff3b6d79908ebb 262 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 210 251 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 LH59_04920 2d515ad131253f451fff3b6d79908ebb 262 SMART SM00342 173 255 1.5E-18 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_04920 2d515ad131253f451fff3b6d79908ebb 262 Pfam PF12833 Helix-turn-helix domain 179 257 7.2E-21 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_04920 2d515ad131253f451fff3b6d79908ebb 262 Gene3D G3DSA:2.60.120.10 7 94 6.2E-8 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_16950 dd7dce23c2140a85f0ce915fe00014a9 243 Gene3D G3DSA:3.40.50.720 2 242 2.9E-38 T 14-10-2018 LH59_16950 dd7dce23c2140a85f0ce915fe00014a9 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 159 1.4E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_16950 dd7dce23c2140a85f0ce915fe00014a9 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.4E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_16950 dd7dce23c2140a85f0ce915fe00014a9 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 1.4E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_16950 dd7dce23c2140a85f0ce915fe00014a9 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 176 1.4E-11 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_16950 dd7dce23c2140a85f0ce915fe00014a9 243 SUPERFAMILY SSF51735 3 210 1.65E-33 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_16950 dd7dce23c2140a85f0ce915fe00014a9 243 Pfam PF00106 short chain dehydrogenase 4 85 4.5E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_26420 6916833ad4df111de862b16eeccb7c76 489 Pfam PF02386 Cation transport protein 38 483 4.1E-62 T 14-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 LH59_26420 6916833ad4df111de862b16eeccb7c76 489 PIRSF PIRSF006247 1 489 7.5E-160 T 14-10-2018 IPR004772 TrkH potassium transport family GO:0015379|GO:0016021|GO:0071805 LH59_05060 678c2502fc6497b78ac465852f1fa7cc 334 Pfam PF01699 Sodium/calcium exchanger protein 5 157 4.0E-13 T 14-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 LH59_05060 678c2502fc6497b78ac465852f1fa7cc 334 Pfam PF01699 Sodium/calcium exchanger protein 194 327 6.7E-9 T 14-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 LH59_05060 678c2502fc6497b78ac465852f1fa7cc 334 Gene3D G3DSA:1.20.58.1130 8 222 1.1E-35 T 14-10-2018 LH59_05060 678c2502fc6497b78ac465852f1fa7cc 334 Gene3D G3DSA:1.20.1420.30 35 306 1.1E-35 T 14-10-2018 LH59_00850 efa60992b48439ab4ce38e563d23fb63 462 Pfam PF02447 GntP family permease 9 457 1.1E-125 T 14-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 LH59_00850 efa60992b48439ab4ce38e563d23fb63 462 PIRSF PIRSF002746 4 460 2.5E-146 T 14-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 LH59_00850 efa60992b48439ab4ce38e563d23fb63 462 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 8 457 3.0E-120 T 14-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 LH59_01030 5bdb9534cd9f1e5745a309d527e166bc 408 Pfam PF06779 Uncharacterised MFS-type transporter YbfB 27 381 6.7E-81 T 14-10-2018 IPR010645 Uncharacterised MFS-type transporter YbfB LH59_01030 5bdb9534cd9f1e5745a309d527e166bc 408 Gene3D G3DSA:1.20.1250.20 17 200 1.1E-8 T 14-10-2018 LH59_01030 5bdb9534cd9f1e5745a309d527e166bc 408 Gene3D G3DSA:1.20.1250.20 215 399 1.7E-10 T 14-10-2018 LH59_01030 5bdb9534cd9f1e5745a309d527e166bc 408 SUPERFAMILY SSF103473 8 385 8.5E-27 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_17195 414d356f8cd780f6a738a16e494784a4 180 Gene3D G3DSA:1.10.10.10 1 149 1.0E-49 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_17195 414d356f8cd780f6a738a16e494784a4 180 Pfam PF02082 Transcriptional regulator 1 83 3.3E-27 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type LH59_17195 414d356f8cd780f6a738a16e494784a4 180 SUPERFAMILY SSF46785 2 137 6.62E-34 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_17195 414d356f8cd780f6a738a16e494784a4 180 TIGRFAM TIGR02010 IscR: iron-sulfur cluster assembly transcription factor IscR 1 139 4.4E-63 T 14-10-2018 IPR010242 Transcription factor HTH, IscR GO:0003690|GO:0003700|GO:0006355 LH59_17195 414d356f8cd780f6a738a16e494784a4 180 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 136 9.5E-42 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type LH59_06420 3146e42e61b44c64e580b6f14a5f2e60 399 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 85 99 - T 14-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 LH59_06420 3146e42e61b44c64e580b6f14a5f2e60 399 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 6 395 51.44 T 14-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 LH59_06420 3146e42e61b44c64e580b6f14a5f2e60 399 Gene3D G3DSA:3.40.50.1100 58 388 7.5E-183 T 14-10-2018 LH59_06420 3146e42e61b44c64e580b6f14a5f2e60 399 Gene3D G3DSA:3.40.50.1100 14 210 7.5E-183 T 14-10-2018 LH59_06420 3146e42e61b44c64e580b6f14a5f2e60 399 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 11 394 1.1E-189 T 14-10-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 LH59_06420 3146e42e61b44c64e580b6f14a5f2e60 399 PIRSF PIRSF001413 2 399 3.8E-161 T 14-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 LH59_06420 3146e42e61b44c64e580b6f14a5f2e60 399 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 58 382 3.3E-48 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme LH59_06420 3146e42e61b44c64e580b6f14a5f2e60 399 SUPERFAMILY SSF53686 7 393 4.98E-147 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme LH59_03595 1e4dc9322ce328128108fb9a1c5bc788 362 Gene3D G3DSA:1.10.287.470 112 171 5.7E-76 T 14-10-2018 LH59_03595 1e4dc9322ce328128108fb9a1c5bc788 362 SUPERFAMILY SSF111369 69 282 7.85E-45 T 14-10-2018 LH59_03595 1e4dc9322ce328128108fb9a1c5bc788 362 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 53 357 6.6E-81 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 LH59_03595 1e4dc9322ce328128108fb9a1c5bc788 362 Gene3D G3DSA:2.40.30.170 68 287 5.7E-76 T 14-10-2018 LH59_03595 1e4dc9322ce328128108fb9a1c5bc788 362 Gene3D G3DSA:2.40.50.100 77 205 5.7E-76 T 14-10-2018 LH59_03595 1e4dc9322ce328128108fb9a1c5bc788 362 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 64 278 5.4E-30 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain LH59_03595 1e4dc9322ce328128108fb9a1c5bc788 362 Gene3D G3DSA:2.40.420.20 288 355 5.7E-76 T 14-10-2018 LH59_12080 52696c7bb81556d7d38c43878ebca04e 362 SMART SM00382 33 217 9.4E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_12080 52696c7bb81556d7d38c43878ebca04e 362 SUPERFAMILY SSF52540 23 248 1.14E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_12080 52696c7bb81556d7d38c43878ebca04e 362 Pfam PF08402 TOBE domain 283 348 2.3E-9 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 LH59_12080 52696c7bb81556d7d38c43878ebca04e 362 Pfam PF00005 ABC transporter 27 167 2.9E-21 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_12080 52696c7bb81556d7d38c43878ebca04e 362 Gene3D G3DSA:3.40.50.300 7 228 2.6E-50 T 14-10-2018 LH59_12080 52696c7bb81556d7d38c43878ebca04e 362 SUPERFAMILY SSF50331 242 357 4.13E-19 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal LH59_12080 52696c7bb81556d7d38c43878ebca04e 362 Gene3D G3DSA:2.40.50.940 229 355 4.7E-17 T 14-10-2018 LH59_12080 52696c7bb81556d7d38c43878ebca04e 362 Gene3D G3DSA:2.40.50.140 290 347 4.7E-17 T 14-10-2018 LH59_19210 0e026b93ba14097c2477baede8f3b101 239 Pfam PF00117 Glutamine amidotransferase class-I 28 187 3.6E-17 T 14-10-2018 IPR017926 Glutamine amidotransferase LH59_19210 0e026b93ba14097c2477baede8f3b101 239 Gene3D G3DSA:3.40.50.880 1 231 2.3E-56 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_19210 0e026b93ba14097c2477baede8f3b101 239 SUPERFAMILY SSF52317 23 233 4.13E-45 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_00910 472bea9d34653abfc516dcfc1fee3e47 263 Pfam PF00902 Sec-independent protein translocase protein (TatC) 18 229 1.5E-65 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 LH59_00910 472bea9d34653abfc516dcfc1fee3e47 263 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 14 41 7.4E-48 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 LH59_00910 472bea9d34653abfc516dcfc1fee3e47 263 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 111 137 7.4E-48 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 LH59_00910 472bea9d34653abfc516dcfc1fee3e47 263 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 93 111 7.4E-48 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 LH59_00910 472bea9d34653abfc516dcfc1fee3e47 263 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 162 190 7.4E-48 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 LH59_00910 472bea9d34653abfc516dcfc1fee3e47 263 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 16 234 2.9E-67 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 LH59_00910 472bea9d34653abfc516dcfc1fee3e47 263 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 11 247 16.88 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 LH59_15580 566254825341f14b316a16513a3070da 406 SUPERFAMILY SSF103473 14 393 1.44E-39 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_15580 566254825341f14b316a16513a3070da 406 Gene3D G3DSA:1.20.1250.20 12 392 2.0E-34 T 14-10-2018 LH59_15580 566254825341f14b316a16513a3070da 406 Pfam PF05977 Transmembrane secretion effector 27 399 1.2E-32 T 14-10-2018 IPR010290 Transmembrane secretion effector LH59_18455 f68158a239f9574b4f239bdcc03e5c36 306 SUPERFAMILY SSF46785 8 112 4.68E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_18455 f68158a239f9574b4f239bdcc03e5c36 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 3.0E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_18455 f68158a239f9574b4f239bdcc03e5c36 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 3.0E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_18455 f68158a239f9574b4f239bdcc03e5c36 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 3.0E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_18455 f68158a239f9574b4f239bdcc03e5c36 306 Gene3D G3DSA:3.40.190.10 98 289 1.0E-34 T 14-10-2018 LH59_18455 f68158a239f9574b4f239bdcc03e5c36 306 Gene3D G3DSA:3.40.190.10 173 276 1.0E-34 T 14-10-2018 LH59_18455 f68158a239f9574b4f239bdcc03e5c36 306 SUPERFAMILY SSF53850 95 299 1.63E-33 T 14-10-2018 LH59_18455 f68158a239f9574b4f239bdcc03e5c36 306 Gene3D G3DSA:1.10.10.10 7 95 8.2E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_18455 f68158a239f9574b4f239bdcc03e5c36 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 69 3.6E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_18455 f68158a239f9574b4f239bdcc03e5c36 306 Pfam PF03466 LysR substrate binding domain 94 298 1.1E-37 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_00640 a02dc4087bb733b33d6273d8db7207f0 566 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 136 145 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 LH59_00640 a02dc4087bb733b33d6273d8db7207f0 566 Gene3D G3DSA:3.40.50.620 126 443 2.8E-154 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LH59_00640 a02dc4087bb733b33d6273d8db7207f0 566 SUPERFAMILY SSF55190 9 118 2.22E-21 T 14-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 LH59_00640 a02dc4087bb733b33d6273d8db7207f0 566 Gene3D G3DSA:3.30.1360.70 5 116 1.5E-23 T 14-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 LH59_00640 a02dc4087bb733b33d6273d8db7207f0 566 SMART SM00836 449 566 2.3E-53 T 14-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 LH59_00640 a02dc4087bb733b33d6273d8db7207f0 566 SMART SM01016 7 98 4.1E-35 T 14-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 LH59_00640 a02dc4087bb733b33d6273d8db7207f0 566 Pfam PF00750 tRNA synthetases class I (R) 109 411 6.6E-22 T 14-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 LH59_00640 a02dc4087bb733b33d6273d8db7207f0 566 PRINTS PR01038 Arginyl-tRNA synthetase signature 126 141 4.6E-23 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 LH59_00640 a02dc4087bb733b33d6273d8db7207f0 566 PRINTS PR01038 Arginyl-tRNA synthetase signature 165 178 4.6E-23 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 LH59_00640 a02dc4087bb733b33d6273d8db7207f0 566 PRINTS PR01038 Arginyl-tRNA synthetase signature 141 157 4.6E-23 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 LH59_00640 a02dc4087bb733b33d6273d8db7207f0 566 PRINTS PR01038 Arginyl-tRNA synthetase signature 316 337 4.6E-23 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 LH59_00640 a02dc4087bb733b33d6273d8db7207f0 566 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 13 566 2.2E-126 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 LH59_00640 a02dc4087bb733b33d6273d8db7207f0 566 Gene3D G3DSA:1.10.730.10 444 566 2.8E-154 T 14-10-2018 LH59_00640 a02dc4087bb733b33d6273d8db7207f0 566 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 13 97 7.0E-23 T 14-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 LH59_00640 a02dc4087bb733b33d6273d8db7207f0 566 Hamap MF_00123 Arginine--tRNA ligase [argS]. 11 566 25.481 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 LH59_00640 a02dc4087bb733b33d6273d8db7207f0 566 Pfam PF05746 DALR anticodon binding domain 449 566 1.7E-34 T 14-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 LH59_00640 a02dc4087bb733b33d6273d8db7207f0 566 SUPERFAMILY SSF47323 444 566 3.79E-37 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 LH59_00640 a02dc4087bb733b33d6273d8db7207f0 566 SUPERFAMILY SSF52374 123 459 1.29E-82 T 14-10-2018 LH59_20355 bb887f618ccb76dabf1a8e8a52628c31 149 TIGRFAM TIGR02695 azurin: azurin 23 147 1.8E-60 T 14-10-2018 IPR014068 Azurin LH59_20355 bb887f618ccb76dabf1a8e8a52628c31 149 ProDom PD003655 COPPER ELECTRON AZURIN METAL-BINDING PERIPLASMIC PRECURSOR SIGNAL SEQUENCING DIRECT MEMBRANE 26 148 6.0E-67 T 14-10-2018 LH59_20355 bb887f618ccb76dabf1a8e8a52628c31 149 Gene3D G3DSA:2.60.40.420 21 149 5.6E-47 T 14-10-2018 IPR008972 Cupredoxin LH59_20355 bb887f618ccb76dabf1a8e8a52628c31 149 Pfam PF00127 Copper binding proteins, plastocyanin/azurin family 21 147 1.4E-29 T 14-10-2018 IPR000923 Blue (type 1) copper domain GO:0005507|GO:0009055 LH59_20355 bb887f618ccb76dabf1a8e8a52628c31 149 ProSitePatterns PS00196 Type-1 copper (blue) proteins signature. 125 141 - T 14-10-2018 IPR028871 Blue (type 1) copper protein, binding site LH59_20355 bb887f618ccb76dabf1a8e8a52628c31 149 SUPERFAMILY SSF49503 22 147 1.85E-45 T 14-10-2018 IPR008972 Cupredoxin LH59_10930 827eb710e518c10bb1f9865882106118 497 Pfam PF07171 MlrC C-terminus 304 481 4.6E-56 T 14-10-2018 IPR010799 Microcystin LR degradation protein MlrC, C-terminal LH59_10930 827eb710e518c10bb1f9865882106118 497 PIRSF PIRSF012702 1 497 8.3E-169 T 14-10-2018 IPR009197 Microcystin LR degradation protein MlrC LH59_10930 827eb710e518c10bb1f9865882106118 497 Pfam PF07364 Metallopeptidase family M81 3 291 4.0E-98 T 14-10-2018 IPR015995 Microcystin LR degradation protein MlrC, N-terminal LH59_18500 439ef4cf2e4a50be1135ebbf2beb7d75 267 Hamap MF_01265 Probable L-aspartate dehydrogenase [nadX]. 3 265 31.994 T 14-10-2018 IPR020626 L-aspartate dehydrogenase, prokaryotic GO:0009435|GO:0033735|GO:0055114 KEGG: 00760+1.4.1.21 LH59_18500 439ef4cf2e4a50be1135ebbf2beb7d75 267 Gene3D G3DSA:3.40.50.720 6 257 3.3E-67 T 14-10-2018 LH59_18500 439ef4cf2e4a50be1135ebbf2beb7d75 267 PIRSF PIRSF005227 1 267 1.1E-79 T 14-10-2018 IPR011182 L-aspartate dehydrogenase GO:0009435|GO:0033735|GO:0055114 KEGG: 00760+1.4.1.21 LH59_18500 439ef4cf2e4a50be1135ebbf2beb7d75 267 SUPERFAMILY SSF55347 121 236 7.85E-26 T 14-10-2018 LH59_18500 439ef4cf2e4a50be1135ebbf2beb7d75 267 Gene3D G3DSA:3.30.360.10 121 240 3.3E-67 T 14-10-2018 LH59_18500 439ef4cf2e4a50be1135ebbf2beb7d75 267 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 118 2.2E-16 T 14-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 LH59_18500 439ef4cf2e4a50be1135ebbf2beb7d75 267 Pfam PF01958 Domain of unknown function DUF108 166 253 2.1E-29 T 14-10-2018 IPR002811 Aspartate dehydrogenase GO:0006742|GO:0016491|GO:0019363|GO:0055114 KEGG: 00760+1.4.1.21 LH59_18500 439ef4cf2e4a50be1135ebbf2beb7d75 267 SUPERFAMILY SSF51735 4 149 1.72E-20 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_27795 a294f1c237d40651ec43daa5a175cb15 106 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 2 101 1.5E-30 T 14-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_27795 a294f1c237d40651ec43daa5a175cb15 106 Gene3D G3DSA:2.30.30.30 1 103 2.5E-33 T 14-10-2018 IPR014722 Ribosomal protein L2, domain 2 LH59_27795 a294f1c237d40651ec43daa5a175cb15 106 ProSitePatterns PS01108 Ribosomal protein L24 signature. 7 24 - T 14-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_27795 a294f1c237d40651ec43daa5a175cb15 106 SUPERFAMILY SSF50104 3 100 1.35E-28 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily LH59_27795 a294f1c237d40651ec43daa5a175cb15 106 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 101 8.0E-23 T 14-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_27795 a294f1c237d40651ec43daa5a175cb15 106 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 2 96 19.192 T 14-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_17365 611566da74e5b766bc03991441a72e5a 512 PIRSF PIRSF000538 3 499 3.8E-102 T 14-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 LH59_17365 611566da74e5b766bc03991441a72e5a 512 SUPERFAMILY SSF53067 5 253 1.77E-53 T 14-10-2018 LH59_17365 611566da74e5b766bc03991441a72e5a 512 Gene3D G3DSA:3.30.420.40 4 250 2.4E-59 T 14-10-2018 LH59_17365 611566da74e5b766bc03991441a72e5a 512 Gene3D G3DSA:3.30.420.40 252 499 1.4E-59 T 14-10-2018 LH59_17365 611566da74e5b766bc03991441a72e5a 512 SUPERFAMILY SSF53067 252 493 1.04E-50 T 14-10-2018 LH59_17365 611566da74e5b766bc03991441a72e5a 512 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 363 383 - T 14-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 LH59_17365 611566da74e5b766bc03991441a72e5a 512 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 250 1.4E-35 T 14-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 LH59_17365 611566da74e5b766bc03991441a72e5a 512 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 259 451 8.9E-39 T 14-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 LH59_01150 e2a465da12c30c42968af7b47daab99e 66 Pfam PF11137 Protein of unknown function (DUF2909) 1 60 1.5E-24 T 14-10-2018 IPR021313 Protein of unknown function DUF2909 LH59_04565 7644f7ad33f1c99063c7e6969dda2ab5 232 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 6 207 5.5E-35 T 14-10-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like LH59_04565 7644f7ad33f1c99063c7e6969dda2ab5 232 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 6 197 6.3E-22 T 14-10-2018 LH59_04565 7644f7ad33f1c99063c7e6969dda2ab5 232 Gene3D G3DSA:3.40.50.1000 6 221 3.5E-83 T 14-10-2018 IPR023214 HAD superfamily LH59_04565 7644f7ad33f1c99063c7e6969dda2ab5 232 Pfam PF12710 haloacid dehalogenase-like hydrolase 7 195 1.2E-39 T 14-10-2018 LH59_04565 7644f7ad33f1c99063c7e6969dda2ab5 232 Gene3D G3DSA:1.20.1440.100 18 92 3.5E-83 T 14-10-2018 LH59_04565 7644f7ad33f1c99063c7e6969dda2ab5 232 SUPERFAMILY SSF56784 4 226 3.73E-31 T 14-10-2018 IPR036412 HAD-like superfamily LH59_00510 76bc4834b4e290fd9cd8fd061d6164f1 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 247 2.5E-65 T 14-10-2018 LH59_00510 76bc4834b4e290fd9cd8fd061d6164f1 253 Gene3D G3DSA:3.40.50.720 2 251 3.0E-85 T 14-10-2018 LH59_00510 76bc4834b4e290fd9cd8fd061d6164f1 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 4.5E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_00510 76bc4834b4e290fd9cd8fd061d6164f1 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 4.5E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_00510 76bc4834b4e290fd9cd8fd061d6164f1 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 4.5E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_00510 76bc4834b4e290fd9cd8fd061d6164f1 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.9E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_00510 76bc4834b4e290fd9cd8fd061d6164f1 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 1.9E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_00510 76bc4834b4e290fd9cd8fd061d6164f1 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.9E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_00510 76bc4834b4e290fd9cd8fd061d6164f1 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 1.9E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_00510 76bc4834b4e290fd9cd8fd061d6164f1 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 1.9E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_00510 76bc4834b4e290fd9cd8fd061d6164f1 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 1.9E-39 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_00510 76bc4834b4e290fd9cd8fd061d6164f1 253 SUPERFAMILY SSF51735 1 250 2.04E-82 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_00510 76bc4834b4e290fd9cd8fd061d6164f1 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 178 2.7E-4 T 14-10-2018 LH59_12435 f2a6b711d382e17387bb4dba3c6e4946 430 SUPERFAMILY SSF55031 224 335 5.63E-21 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain LH59_12435 f2a6b711d382e17387bb4dba3c6e4946 430 PIRSF PIRSF037238 32 423 8.3E-100 T 14-10-2018 IPR017150 Peptidase M20, glutamate carboxypeptidase LH59_12435 f2a6b711d382e17387bb4dba3c6e4946 430 Gene3D G3DSA:3.40.630.10 48 411 2.3E-108 T 14-10-2018 LH59_12435 f2a6b711d382e17387bb4dba3c6e4946 430 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 117 126 - T 14-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 LH59_12435 f2a6b711d382e17387bb4dba3c6e4946 430 Pfam PF07687 Peptidase dimerisation domain 221 321 9.0E-18 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain LH59_12435 f2a6b711d382e17387bb4dba3c6e4946 430 Gene3D G3DSA:3.30.70.360 223 332 2.3E-108 T 14-10-2018 LH59_12435 f2a6b711d382e17387bb4dba3c6e4946 430 Pfam PF01546 Peptidase family M20/M25/M40 118 420 6.7E-24 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 LH59_12435 f2a6b711d382e17387bb4dba3c6e4946 430 SUPERFAMILY SSF53187 33 392 9.14E-46 T 14-10-2018 LH59_27450 938c5eda8a21362585d3ad8abbab344d 325 Gene3D G3DSA:3.90.25.10 179 317 2.1E-90 T 14-10-2018 LH59_27450 938c5eda8a21362585d3ad8abbab344d 325 SUPERFAMILY SSF51735 2 322 4.42E-88 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_27450 938c5eda8a21362585d3ad8abbab344d 325 Gene3D G3DSA:3.40.50.720 9 305 2.1E-90 T 14-10-2018 LH59_27450 938c5eda8a21362585d3ad8abbab344d 325 Pfam PF01370 NAD dependent epimerase/dehydratase family 8 247 4.0E-56 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 LH59_21145 9f9c9d16eb63387166877d9b6d3b3b95 252 Pfam PF00561 alpha/beta hydrolase fold 14 129 9.5E-16 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_21145 9f9c9d16eb63387166877d9b6d3b3b95 252 Gene3D G3DSA:3.40.50.1820 4 249 3.6E-47 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_21145 9f9c9d16eb63387166877d9b6d3b3b95 252 SUPERFAMILY SSF53474 6 249 1.23E-46 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_26510 70ddc4f476e70a8ae97865fc6db990db 302 SUPERFAMILY SSF51569 2 288 8.94E-75 T 14-10-2018 LH59_26510 70ddc4f476e70a8ae97865fc6db990db 302 Pfam PF00682 HMGL-like 6 278 6.8E-56 T 14-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 LH59_26510 70ddc4f476e70a8ae97865fc6db990db 302 Gene3D G3DSA:3.20.20.70 1 300 3.4E-134 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_26510 70ddc4f476e70a8ae97865fc6db990db 302 ProSitePatterns PS01062 Hydroxymethylglutaryl-coenzyme A lyase active site. 233 242 - T 14-10-2018 IPR000138 Hydroxymethylglutaryl-CoA lyase, active site GO:0004419 KEGG: 00072+4.1.3.4|KEGG: 00280+4.1.3.4|KEGG: 00281+4.1.3.4|KEGG: 00650+4.1.3.4|MetaCyc: PWY-5074|Reactome: R-HSA-77111|Reactome: R-HSA-9033241 LH59_09905 426feba35a581b7443ab4e24ac7a6bf3 416 Pfam PF07690 Major Facilitator Superfamily 39 264 4.6E-24 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_09905 426feba35a581b7443ab4e24ac7a6bf3 416 Gene3D G3DSA:1.20.1250.20 234 415 1.3E-19 T 14-10-2018 LH59_09905 426feba35a581b7443ab4e24ac7a6bf3 416 SUPERFAMILY SSF103473 8 414 1.44E-55 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_09905 426feba35a581b7443ab4e24ac7a6bf3 416 Gene3D G3DSA:1.20.1250.20 29 213 1.4E-20 T 14-10-2018 LH59_07050 08bca6ab2eb57e4e7d9073bbade3fb36 336 Pfam PF01479 S4 domain 45 90 6.9E-9 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_07050 08bca6ab2eb57e4e7d9073bbade3fb36 336 Pfam PF00849 RNA pseudouridylate synthase 118 275 7.2E-31 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 LH59_07050 08bca6ab2eb57e4e7d9073bbade3fb36 336 Gene3D G3DSA:3.10.290.10 33 97 4.6E-16 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 LH59_07050 08bca6ab2eb57e4e7d9073bbade3fb36 336 SMART SM00363 44 109 1.4E-4 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_07050 08bca6ab2eb57e4e7d9073bbade3fb36 336 SUPERFAMILY SSF55174 45 95 3.2E-9 T 14-10-2018 LH59_07050 08bca6ab2eb57e4e7d9073bbade3fb36 336 Gene3D G3DSA:3.30.2350.10 111 333 5.6E-63 T 14-10-2018 LH59_07050 08bca6ab2eb57e4e7d9073bbade3fb36 336 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 41 330 7.1E-78 T 14-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 LH59_07050 08bca6ab2eb57e4e7d9073bbade3fb36 336 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 161 175 - T 14-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 LH59_07050 08bca6ab2eb57e4e7d9073bbade3fb36 336 SUPERFAMILY SSF55120 104 333 4.93E-65 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 LH59_21635 ebea637821678240fb20164d4defbef4 505 Gene3D G3DSA:3.40.1080.20 336 476 1.1E-39 T 14-10-2018 IPR038460 Acetyl-CoA hydrolase/transferase, C-terminal domain superfamily LH59_21635 ebea637821678240fb20164d4defbef4 505 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 322 463 3.8E-42 T 14-10-2018 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain LH59_21635 ebea637821678240fb20164d4defbef4 505 SUPERFAMILY SSF100950 227 495 4.94E-79 T 14-10-2018 IPR037171 NagB/RpiA transferase-like LH59_21635 ebea637821678240fb20164d4defbef4 505 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 14 215 1.5E-30 T 14-10-2018 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 LH59_21635 ebea637821678240fb20164d4defbef4 505 TIGRFAM TIGR03458 YgfH_subfam: succinate CoA transferase 12 494 7.3E-229 T 14-10-2018 IPR017821 Succinate CoA transferase GO:0006084|GO:0016740 LH59_21635 ebea637821678240fb20164d4defbef4 505 Gene3D G3DSA:3.40.1080.10 13 181 1.5E-17 T 14-10-2018 LH59_21635 ebea637821678240fb20164d4defbef4 505 SUPERFAMILY SSF100950 4 222 2.64E-70 T 14-10-2018 IPR037171 NagB/RpiA transferase-like LH59_04330 131c3c16ce22e920bf3e49f4c195b372 215 SUPERFAMILY SSF103088 98 210 9.29E-37 T 14-10-2018 IPR036737 OmpA-like domain superfamily LH59_04330 131c3c16ce22e920bf3e49f4c195b372 215 Gene3D G3DSA:3.30.1330.60 74 215 1.7E-41 T 14-10-2018 IPR036737 OmpA-like domain superfamily LH59_04330 131c3c16ce22e920bf3e49f4c195b372 215 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 173 192 1.0E-5 T 14-10-2018 LH59_04330 131c3c16ce22e920bf3e49f4c195b372 215 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 193 213 1.0E-5 T 14-10-2018 LH59_04330 131c3c16ce22e920bf3e49f4c195b372 215 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 155 172 1.0E-5 T 14-10-2018 LH59_04330 131c3c16ce22e920bf3e49f4c195b372 215 PRINTS PR01021 OMPA domain signature 110 132 7.4E-13 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 LH59_04330 131c3c16ce22e920bf3e49f4c195b372 215 PRINTS PR01021 OMPA domain signature 140 155 7.4E-13 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 LH59_04330 131c3c16ce22e920bf3e49f4c195b372 215 PRINTS PR01021 OMPA domain signature 155 171 7.4E-13 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 LH59_04330 131c3c16ce22e920bf3e49f4c195b372 215 Pfam PF13441 YMGG-like Gly-zipper 30 71 2.2E-8 T 14-10-2018 IPR027367 YMGG-like Gly-zipper LH59_04330 131c3c16ce22e920bf3e49f4c195b372 215 Pfam PF00691 OmpA family 110 204 5.0E-20 T 14-10-2018 IPR006665 OmpA-like domain LH59_04110 a74e6e871620354ac12b3b90e6971fdc 564 Gene3D G3DSA:3.40.50.970 1 180 1.2E-56 T 14-10-2018 LH59_04110 a74e6e871620354ac12b3b90e6971fdc 564 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 403 547 7.4E-40 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 LH59_04110 a74e6e871620354ac12b3b90e6971fdc 564 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 437 456 - T 14-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 LH59_04110 a74e6e871620354ac12b3b90e6971fdc 564 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 197 333 1.8E-31 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 LH59_04110 a74e6e871620354ac12b3b90e6971fdc 564 Gene3D G3DSA:3.40.50.1220 190 371 3.0E-43 T 14-10-2018 LH59_04110 a74e6e871620354ac12b3b90e6971fdc 564 SUPERFAMILY SSF52467 189 392 6.93E-42 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily LH59_04110 a74e6e871620354ac12b3b90e6971fdc 564 Gene3D G3DSA:3.40.50.970 372 562 2.9E-58 T 14-10-2018 LH59_04110 a74e6e871620354ac12b3b90e6971fdc 564 SUPERFAMILY SSF52518 376 552 9.32E-56 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold LH59_04110 a74e6e871620354ac12b3b90e6971fdc 564 SUPERFAMILY SSF52518 3 178 5.89E-50 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold LH59_04110 a74e6e871620354ac12b3b90e6971fdc 564 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 173 8.4E-54 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 LH59_17905 a747d7f5227628b0d51e91bc50853124 153 Gene3D G3DSA:2.60.120.1140 22 150 3.2E-41 T 14-10-2018 IPR038695 Saro_0823-like superfamily LH59_17905 a747d7f5227628b0d51e91bc50853124 153 Pfam PF02643 Uncharacterized ACR, COG1430 48 149 2.2E-33 T 14-10-2018 IPR003795 Protein of unknown function DUF192 LH59_16605 f2b35f97e05696d9c092941de7da2500 541 Pfam PF02203 Tar ligand binding domain homologue 1 169 5.1E-21 T 14-10-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 LH59_16605 f2b35f97e05696d9c092941de7da2500 541 Pfam PF00672 HAMP domain 216 264 8.3E-8 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_16605 f2b35f97e05696d9c092941de7da2500 541 SMART SM00283 269 516 2.9E-92 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 LH59_16605 f2b35f97e05696d9c092941de7da2500 541 Gene3D G3DSA:1.10.287.950 216 518 1.0E-92 T 14-10-2018 LH59_16605 f2b35f97e05696d9c092941de7da2500 541 SMART SM00304 216 268 1.7E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_16605 f2b35f97e05696d9c092941de7da2500 541 SUPERFAMILY SSF47170 28 179 1.18E-5 T 14-10-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain superfamily LH59_16605 f2b35f97e05696d9c092941de7da2500 541 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 327 484 3.0E-55 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 LH59_16605 f2b35f97e05696d9c092941de7da2500 541 SUPERFAMILY SSF58104 236 520 1.07E-73 T 14-10-2018 LH59_16605 f2b35f97e05696d9c092941de7da2500 541 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 5 30 6.7E-63 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_16605 f2b35f97e05696d9c092941de7da2500 541 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 444 473 6.7E-63 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_16605 f2b35f97e05696d9c092941de7da2500 541 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 61 76 6.7E-63 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_16605 f2b35f97e05696d9c092941de7da2500 541 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 367 394 6.7E-63 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_16605 f2b35f97e05696d9c092941de7da2500 541 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 290 319 6.7E-63 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_16605 f2b35f97e05696d9c092941de7da2500 541 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 396 425 6.7E-63 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_12450 43a5fc302683f3bae20d7c034484b9cb 223 SMART SM00382 35 220 3.6E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_12450 43a5fc302683f3bae20d7c034484b9cb 223 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_12450 43a5fc302683f3bae20d7c034484b9cb 223 Gene3D G3DSA:3.40.50.300 5 223 5.6E-67 T 14-10-2018 LH59_12450 43a5fc302683f3bae20d7c034484b9cb 223 SUPERFAMILY SSF52540 7 221 5.32E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_12450 43a5fc302683f3bae20d7c034484b9cb 223 Pfam PF00005 ABC transporter 26 171 1.9E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_15935 5aeee636c820725d53f6bf9e285ac0bf 411 Pfam PF07690 Major Facilitator Superfamily 36 368 5.1E-32 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_15935 5aeee636c820725d53f6bf9e285ac0bf 411 SUPERFAMILY SSF103473 17 399 1.96E-49 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_15935 5aeee636c820725d53f6bf9e285ac0bf 411 Gene3D G3DSA:1.20.1250.20 30 403 1.2E-42 T 14-10-2018 LH59_23530 1dbf4b72663e3a8ae22efb4ad50af488 216 Pfam PF09859 Oxygenase, catalysing oxidative methylation of damaged DNA 62 207 6.4E-38 T 14-10-2018 IPR018655 Protein of unknown function DUF2086 LH59_00765 5df387c4b9b9994a90af1a9dd5cb8f80 504 Pfam PF00271 Helicase conserved C-terminal domain 240 344 4.1E-25 T 14-10-2018 IPR001650 Helicase, C-terminal LH59_00765 5df387c4b9b9994a90af1a9dd5cb8f80 504 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 158 166 - T 14-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site LH59_00765 5df387c4b9b9994a90af1a9dd5cb8f80 504 Pfam PF00270 DEAD/DEAH box helicase 29 199 3.2E-49 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 LH59_00765 5df387c4b9b9994a90af1a9dd5cb8f80 504 SMART SM00487 24 227 2.9E-62 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain LH59_00765 5df387c4b9b9994a90af1a9dd5cb8f80 504 Hamap MF_00968 ATP-dependent RNA helicase RhlE [rhlE]. 5 494 49.315 T 14-10-2018 IPR028622 ATP-dependent RNA helicase RhlE GO:0004004|GO:0042255 LH59_00765 5df387c4b9b9994a90af1a9dd5cb8f80 504 SMART SM00490 263 344 2.4E-29 T 14-10-2018 IPR001650 Helicase, C-terminal LH59_00765 5df387c4b9b9994a90af1a9dd5cb8f80 504 SUPERFAMILY SSF52540 79 365 2.28E-71 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_00765 5df387c4b9b9994a90af1a9dd5cb8f80 504 Gene3D G3DSA:3.40.50.300 219 401 3.8E-47 T 14-10-2018 LH59_00765 5df387c4b9b9994a90af1a9dd5cb8f80 504 Gene3D G3DSA:3.40.50.300 2 215 5.8E-77 T 14-10-2018 LH59_20375 7c69bf03965158e26153cd1462b45aec 301 SMART SM00382 30 210 2.4E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_20375 7c69bf03965158e26153cd1462b45aec 301 Gene3D G3DSA:3.40.50.300 1 227 3.2E-64 T 14-10-2018 LH59_20375 7c69bf03965158e26153cd1462b45aec 301 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_20375 7c69bf03965158e26153cd1462b45aec 301 Pfam PF00005 ABC transporter 22 161 3.2E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_20375 7c69bf03965158e26153cd1462b45aec 301 SUPERFAMILY SSF52540 6 224 6.2E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_08560 829f06180ccf3de17486520fcb91b85f 271 Gene3D G3DSA:3.20.20.140 1 271 1.2E-82 T 14-10-2018 LH59_08560 829f06180ccf3de17486520fcb91b85f 271 SUPERFAMILY SSF51556 1 270 2.23E-77 T 14-10-2018 IPR032466 Metal-dependent hydrolase LH59_08560 829f06180ccf3de17486520fcb91b85f 271 Pfam PF04909 Amidohydrolase 6 270 3.0E-43 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 LH59_24150 4f05d2936732e33f7748680328d1745e 535 Gene3D G3DSA:3.40.50.970 1 173 4.6E-48 T 14-10-2018 LH59_24150 4f05d2936732e33f7748680328d1745e 535 Gene3D G3DSA:3.40.50.1220 180 351 4.2E-28 T 14-10-2018 LH59_24150 4f05d2936732e33f7748680328d1745e 535 Gene3D G3DSA:3.40.50.970 352 532 9.0E-44 T 14-10-2018 LH59_24150 4f05d2936732e33f7748680328d1745e 535 SUPERFAMILY SSF52518 2 171 5.05E-40 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold LH59_24150 4f05d2936732e33f7748680328d1745e 535 SUPERFAMILY SSF52518 356 529 1.75E-44 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold LH59_24150 4f05d2936732e33f7748680328d1745e 535 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 378 523 1.3E-29 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 LH59_24150 4f05d2936732e33f7748680328d1745e 535 SUPERFAMILY SSF52467 152 344 1.96E-28 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily LH59_24150 4f05d2936732e33f7748680328d1745e 535 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 3 167 1.4E-41 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 LH59_24150 4f05d2936732e33f7748680328d1745e 535 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 189 324 6.1E-21 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 LH59_20890 50defd61f9e0cd1529ea4885b468f588 230 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 11 210 4.8E-28 T 14-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 LH59_20675 16a9366e97bfabcbe3f39d9bb4a10522 542 Pfam PF13570 PQQ-like domain 446 484 6.0E-4 T 14-10-2018 IPR025666 Pyrrolo-quinoline quinone-like domain LH59_20675 16a9366e97bfabcbe3f39d9bb4a10522 542 Gene3D G3DSA:2.130.10.10 364 535 7.0E-11 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 LH59_20675 16a9366e97bfabcbe3f39d9bb4a10522 542 SUPERFAMILY SSF50998 10 523 8.24E-12 T 14-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily LH59_20675 16a9366e97bfabcbe3f39d9bb4a10522 542 Gene3D G3DSA:2.130.10.10 4 135 2.2E-6 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 LH59_20655 1bcdc19373e9f8007b76bd3efc27f270 210 Pfam PF04299 Putative FMN-binding domain 1 167 8.8E-64 T 14-10-2018 IPR007396 Transcriptional regulator PAI 2-type LH59_20655 1bcdc19373e9f8007b76bd3efc27f270 210 PIRSF PIRSF010372 1 206 5.9E-70 T 14-10-2018 IPR007396 Transcriptional regulator PAI 2-type LH59_20655 1bcdc19373e9f8007b76bd3efc27f270 210 Gene3D G3DSA:2.30.110.10 1 207 1.1E-72 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 LH59_20655 1bcdc19373e9f8007b76bd3efc27f270 210 SUPERFAMILY SSF50475 12 192 1.34E-42 T 14-10-2018 LH59_17445 764b80a7c67d9729e58dc18e5f835333 242 TIGRFAM TIGR01600 phage_tail_L: phage minor tail protein L 6 239 7.2E-85 T 14-10-2018 IPR006487 Bacteriophage lambda, GpL, minor tail LH59_17445 764b80a7c67d9729e58dc18e5f835333 242 Pfam PF05100 Phage minor tail protein L 25 239 3.7E-70 T 14-10-2018 IPR006487 Bacteriophage lambda, GpL, minor tail LH59_01515 5579aa8dc96771ea9a675d0a5a83d40a 411 Pfam PF00174 Oxidoreductase molybdopterin binding domain 96 267 2.1E-50 T 14-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 LH59_01515 5579aa8dc96771ea9a675d0a5a83d40a 411 PRINTS PR00407 Eukaryotic molybdopterin domain signature 333 345 3.3E-13 T 14-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 LH59_01515 5579aa8dc96771ea9a675d0a5a83d40a 411 PRINTS PR00407 Eukaryotic molybdopterin domain signature 294 306 3.3E-13 T 14-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 LH59_01515 5579aa8dc96771ea9a675d0a5a83d40a 411 PRINTS PR00407 Eukaryotic molybdopterin domain signature 230 243 3.3E-13 T 14-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 LH59_01515 5579aa8dc96771ea9a675d0a5a83d40a 411 PRINTS PR00407 Eukaryotic molybdopterin domain signature 213 229 3.3E-13 T 14-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 LH59_01515 5579aa8dc96771ea9a675d0a5a83d40a 411 PRINTS PR00407 Eukaryotic molybdopterin domain signature 160 175 3.3E-13 T 14-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 LH59_01515 5579aa8dc96771ea9a675d0a5a83d40a 411 PRINTS PR00407 Eukaryotic molybdopterin domain signature 80 96 3.3E-13 T 14-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 LH59_01515 5579aa8dc96771ea9a675d0a5a83d40a 411 PRINTS PR00407 Eukaryotic molybdopterin domain signature 378 390 3.3E-13 T 14-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 LH59_01515 5579aa8dc96771ea9a675d0a5a83d40a 411 SUPERFAMILY SSF56524 57 327 3.01E-74 T 14-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 LH59_01515 5579aa8dc96771ea9a675d0a5a83d40a 411 Gene3D G3DSA:3.90.420.10 37 295 5.5E-96 T 14-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 LH59_01515 5579aa8dc96771ea9a675d0a5a83d40a 411 Gene3D G3DSA:2.60.40.650 296 411 1.9E-35 T 14-10-2018 LH59_01515 5579aa8dc96771ea9a675d0a5a83d40a 411 Pfam PF03404 Mo-co oxidoreductase dimerisation domain 294 407 4.6E-11 T 14-10-2018 IPR005066 Moybdenum cofactor oxidoreductase, dimerisation GO:0016491|GO:0030151|GO:0055114 Reactome: R-HSA-1614517 LH59_01515 5579aa8dc96771ea9a675d0a5a83d40a 411 SUPERFAMILY SSF81296 297 409 3.29E-30 T 14-10-2018 IPR014756 Immunoglobulin E-set LH59_28215 e04dd85ad73fed9e5515770b2b57cec8 400 SUPERFAMILY SSF55031 184 297 3.44E-30 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain LH59_28215 e04dd85ad73fed9e5515770b2b57cec8 400 Gene3D G3DSA:3.30.70.360 182 296 1.0E-137 T 14-10-2018 LH59_28215 e04dd85ad73fed9e5515770b2b57cec8 400 Gene3D G3DSA:3.40.630.10 15 381 1.0E-137 T 14-10-2018 LH59_28215 e04dd85ad73fed9e5515770b2b57cec8 400 SUPERFAMILY SSF53187 3 398 6.0E-91 T 14-10-2018 LH59_28215 e04dd85ad73fed9e5515770b2b57cec8 400 Pfam PF07687 Peptidase dimerisation domain 187 279 2.4E-12 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain LH59_28215 e04dd85ad73fed9e5515770b2b57cec8 400 Pfam PF01546 Peptidase family M20/M25/M40 73 393 9.9E-38 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 LH59_28215 e04dd85ad73fed9e5515770b2b57cec8 400 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 14 383 1.2E-109 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 LH59_28215 e04dd85ad73fed9e5515770b2b57cec8 400 PIRSF PIRSF005962 1 400 5.1E-125 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 LH59_00730 a0dfdfe4c3d9a99f22124de9060bc233 304 SUPERFAMILY SSF103481 201 302 8.89E-12 T 14-10-2018 LH59_00730 a0dfdfe4c3d9a99f22124de9060bc233 304 Pfam PF00892 EamA-like transporter family 167 299 1.4E-15 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_00730 a0dfdfe4c3d9a99f22124de9060bc233 304 Pfam PF00892 EamA-like transporter family 19 153 7.5E-25 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_00730 a0dfdfe4c3d9a99f22124de9060bc233 304 SUPERFAMILY SSF103481 54 156 8.63E-15 T 14-10-2018 LH59_14095 796f145c660ab504826c1382340b1b6a 388 Gene3D G3DSA:2.102.10.10 37 165 6.9E-39 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 LH59_14095 796f145c660ab504826c1382340b1b6a 388 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 177 379 5.9E-35 T 14-10-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0044237|GO:0051537|GO:0055114 LH59_14095 796f145c660ab504826c1382340b1b6a 388 Gene3D G3DSA:3.90.380.10 17 374 6.9E-39 T 14-10-2018 LH59_14095 796f145c660ab504826c1382340b1b6a 388 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 24 49 1.9E-6 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 LH59_14095 796f145c660ab504826c1382340b1b6a 388 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 74 94 1.9E-6 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 LH59_14095 796f145c660ab504826c1382340b1b6a 388 Pfam PF00355 Rieske [2Fe-2S] domain 41 136 6.1E-10 T 14-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 LH59_14095 796f145c660ab504826c1382340b1b6a 388 SUPERFAMILY SSF50022 8 155 8.38E-30 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 LH59_14095 796f145c660ab504826c1382340b1b6a 388 SUPERFAMILY SSF55961 163 379 1.02E-42 T 14-10-2018 LH59_26540 380dde7b0692a7e760865c809f11b99b 614 Gene3D G3DSA:3.10.620.30 249 368 9.3E-24 T 14-10-2018 LH59_26540 380dde7b0692a7e760865c809f11b99b 614 Pfam PF01841 Transglutaminase-like superfamily 255 360 3.0E-8 T 14-10-2018 IPR002931 Transglutaminase-like LH59_26540 380dde7b0692a7e760865c809f11b99b 614 Pfam PF12969 Domain of Unknown Function with PDB structure (DUF3857) 38 198 1.4E-21 T 14-10-2018 IPR024618 Domain of unknown function DUF3857 LH59_26540 380dde7b0692a7e760865c809f11b99b 614 SMART SM00460 297 365 0.0017 T 14-10-2018 IPR002931 Transglutaminase-like LH59_26540 380dde7b0692a7e760865c809f11b99b 614 SUPERFAMILY SSF54001 260 372 1.23E-11 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily LH59_19250 dcf583120efe3fc94fbff9f297a19336 156 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 38 46 - T 14-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 LH59_19250 dcf583120efe3fc94fbff9f297a19336 156 Gene3D G3DSA:3.10.20.30 1 75 3.3E-26 T 14-10-2018 IPR012675 Beta-grasp domain superfamily LH59_19250 dcf583120efe3fc94fbff9f297a19336 156 SUPERFAMILY SSF47741 83 151 4.45E-29 T 14-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily LH59_19250 dcf583120efe3fc94fbff9f297a19336 156 Gene3D G3DSA:1.10.150.120 77 155 1.6E-25 T 14-10-2018 LH59_19250 dcf583120efe3fc94fbff9f297a19336 156 Pfam PF01799 [2Fe-2S] binding domain 72 144 3.4E-27 T 14-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 LH59_19250 dcf583120efe3fc94fbff9f297a19336 156 SUPERFAMILY SSF54292 3 86 1.84E-25 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 LH59_19250 dcf583120efe3fc94fbff9f297a19336 156 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 5 62 3.7E-7 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 LH59_07510 d8bb05f04b5899dc0b4e94cd5b2df605 262 TIGRFAM TIGR02280 PaaB1: phenylacetate degradation probable enoyl-CoA hydratase PaaB 7 262 5.4E-136 T 14-10-2018 IPR011968 Phenylacetate degradation probable enoyl-CoA hydratase PaaB GO:0010124 KEGG: 00360+5.3.3.18 LH59_07510 d8bb05f04b5899dc0b4e94cd5b2df605 262 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 262 5.5E-60 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 LH59_07510 d8bb05f04b5899dc0b4e94cd5b2df605 262 Gene3D G3DSA:1.10.12.10 205 262 1.4E-23 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal LH59_07510 d8bb05f04b5899dc0b4e94cd5b2df605 262 SUPERFAMILY SSF52096 1 261 1.1E-76 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily LH59_07510 d8bb05f04b5899dc0b4e94cd5b2df605 262 Gene3D G3DSA:3.90.226.10 1 203 1.0E-65 T 14-10-2018 LH59_18795 6d2a0c81171da20f8822cf451a4bbdd0 393 SUPERFAMILY SSF53901 22 377 1.38E-44 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_18795 6d2a0c81171da20f8822cf451a4bbdd0 393 Pfam PF02803 Thiolase, C-terminal domain 264 361 6.3E-11 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 LH59_18795 6d2a0c81171da20f8822cf451a4bbdd0 393 PIRSF PIRSF000429 3 390 2.4E-62 T 14-10-2018 IPR002155 Thiolase GO:0016747 LH59_18795 6d2a0c81171da20f8822cf451a4bbdd0 393 Pfam PF00108 Thiolase, N-terminal domain 7 229 4.5E-25 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 LH59_18795 6d2a0c81171da20f8822cf451a4bbdd0 393 Gene3D G3DSA:3.40.47.10 6 390 1.2E-105 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_12285 8d74836ef3c647253c1fd9c466fa7a8e 349 Gene3D G3DSA:3.50.30.60 204 339 3.2E-44 T 14-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily LH59_12285 8d74836ef3c647253c1fd9c466fa7a8e 349 SUPERFAMILY SSF52317 56 203 3.98E-30 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_12285 8d74836ef3c647253c1fd9c466fa7a8e 349 PIRSF PIRSF028757 52 348 2.5E-69 T 14-10-2018 IPR003507 Peptidase family S66 LH59_12285 8d74836ef3c647253c1fd9c466fa7a8e 349 Gene3D G3DSA:3.40.50.10740 53 200 9.8E-34 T 14-10-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal LH59_12285 8d74836ef3c647253c1fd9c466fa7a8e 349 SUPERFAMILY SSF141986 186 337 8.89E-43 T 14-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily LH59_12285 8d74836ef3c647253c1fd9c466fa7a8e 349 Pfam PF02016 LD-carboxypeptidase 57 331 3.1E-70 T 14-10-2018 IPR003507 Peptidase family S66 LH59_14550 0f92db008b4859c10c55aa916fb9a898 461 SUPERFAMILY SSF103473 26 455 2.09E-36 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_14550 0f92db008b4859c10c55aa916fb9a898 461 Gene3D G3DSA:1.20.1250.20 1 231 1.4E-80 T 14-10-2018 LH59_14550 0f92db008b4859c10c55aa916fb9a898 461 Pfam PF07690 Major Facilitator Superfamily 36 370 2.0E-12 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_14550 0f92db008b4859c10c55aa916fb9a898 461 Gene3D G3DSA:1.20.1250.20 232 458 1.3E-75 T 14-10-2018 LH59_14550 0f92db008b4859c10c55aa916fb9a898 461 TIGRFAM TIGR00886 2A0108: nitrite transporter 27 413 4.9E-105 T 14-10-2018 IPR004737 Nitrate transporter GO:0015112|GO:0015113|GO:0015706|GO:0015707|GO:0016021 LH59_00460 ead6515f70113de5bb39537aec84aef7 196 SUPERFAMILY SSF52499 6 190 1.44E-37 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 LH59_00460 ead6515f70113de5bb39537aec84aef7 196 Gene3D G3DSA:3.40.50.850 6 193 9.5E-37 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 LH59_00460 ead6515f70113de5bb39537aec84aef7 196 Pfam PF00857 Isochorismatase family 13 184 5.5E-19 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 LH59_08710 f544453953d764168ab3fc6c7d38b360 577 SUPERFAMILY SSF161098 375 564 1.1E-18 T 14-10-2018 IPR035906 MetI-like superfamily LH59_08710 f544453953d764168ab3fc6c7d38b360 577 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 252 9.5E-11 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_08710 f544453953d764168ab3fc6c7d38b360 577 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 393 561 2.0E-13 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_08710 f544453953d764168ab3fc6c7d38b360 577 Gene3D G3DSA:1.10.3720.10 62 265 6.1E-26 T 14-10-2018 IPR035906 MetI-like superfamily LH59_08710 f544453953d764168ab3fc6c7d38b360 577 Gene3D G3DSA:1.10.3720.10 373 569 8.0E-18 T 14-10-2018 IPR035906 MetI-like superfamily LH59_08710 f544453953d764168ab3fc6c7d38b360 577 SUPERFAMILY SSF161098 63 256 1.96E-20 T 14-10-2018 IPR035906 MetI-like superfamily LH59_21035 d9e971b72f4a9188f0beab11a2efbbd1 251 PIRSF PIRSF039085 4 251 1.5E-97 T 14-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 LH59_21035 d9e971b72f4a9188f0beab11a2efbbd1 251 Gene3D G3DSA:3.40.50.300 5 251 5.2E-77 T 14-10-2018 LH59_21035 d9e971b72f4a9188f0beab11a2efbbd1 251 SMART SM00382 37 232 3.2E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_21035 d9e971b72f4a9188f0beab11a2efbbd1 251 Pfam PF00005 ABC transporter 28 176 7.1E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_21035 d9e971b72f4a9188f0beab11a2efbbd1 251 SUPERFAMILY SSF52540 7 246 3.22E-78 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_21035 d9e971b72f4a9188f0beab11a2efbbd1 251 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_20700 323ea6eb0a5feaadeea8b155c9011b81 221 Gene3D G3DSA:1.10.10.10 123 219 2.8E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_20700 323ea6eb0a5feaadeea8b155c9011b81 221 SMART SM00448 1 112 2.8E-32 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_20700 323ea6eb0a5feaadeea8b155c9011b81 221 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 216 2.0E-21 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_20700 323ea6eb0a5feaadeea8b155c9011b81 221 SMART SM00862 145 216 7.8E-26 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_20700 323ea6eb0a5feaadeea8b155c9011b81 221 Gene3D G3DSA:3.40.50.2300 1 121 6.5E-36 T 14-10-2018 LH59_20700 323ea6eb0a5feaadeea8b155c9011b81 221 SUPERFAMILY SSF52172 1 171 3.62E-34 T 14-10-2018 IPR011006 CheY-like superfamily LH59_20700 323ea6eb0a5feaadeea8b155c9011b81 221 Pfam PF00072 Response regulator receiver domain 3 112 1.1E-21 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_26370 4d4205d1c8196c014c8a3354d08399e1 250 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 14-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 LH59_26370 4d4205d1c8196c014c8a3354d08399e1 250 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 2 246 3.2E-118 T 14-10-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 LH59_26370 4d4205d1c8196c014c8a3354d08399e1 250 SUPERFAMILY SSF53254 1 245 8.25E-80 T 14-10-2018 IPR029033 Histidine phosphatase superfamily LH59_26370 4d4205d1c8196c014c8a3354d08399e1 250 Gene3D G3DSA:3.40.50.1240 1 248 1.2E-91 T 14-10-2018 IPR029033 Histidine phosphatase superfamily LH59_26370 4d4205d1c8196c014c8a3354d08399e1 250 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 1 228 45.531 T 14-10-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 LH59_26370 4d4205d1c8196c014c8a3354d08399e1 250 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 128 219 1.5E-6 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 LH59_26370 4d4205d1c8196c014c8a3354d08399e1 250 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 121 1.6E-30 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 LH59_26370 4d4205d1c8196c014c8a3354d08399e1 250 PIRSF PIRSF000709 128 221 0.063 T 14-10-2018 LH59_26370 4d4205d1c8196c014c8a3354d08399e1 250 PIRSF PIRSF000709 2 112 7.7E-8 T 14-10-2018 LH59_26370 4d4205d1c8196c014c8a3354d08399e1 250 SMART SM00855 3 189 8.9E-30 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 LH59_03175 9818f857160f0abd475245e2f4a299ab 153 Pfam PF00364 Biotin-requiring enzyme 79 152 3.3E-25 T 14-10-2018 IPR000089 Biotin/lipoyl attachment LH59_03175 9818f857160f0abd475245e2f4a299ab 153 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 1 152 4.2E-54 T 14-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 LH59_03175 9818f857160f0abd475245e2f4a299ab 153 Gene3D G3DSA:2.40.50.100 74 152 2.8E-33 T 14-10-2018 LH59_03175 9818f857160f0abd475245e2f4a299ab 153 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 109 126 - T 14-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LH59_03175 9818f857160f0abd475245e2f4a299ab 153 SUPERFAMILY SSF51230 77 152 1.11E-25 T 14-10-2018 IPR011053 Single hybrid motif LH59_03175 9818f857160f0abd475245e2f4a299ab 153 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 82 95 9.2E-18 T 14-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 LH59_03175 9818f857160f0abd475245e2f4a299ab 153 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 99 113 9.2E-18 T 14-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 LH59_03175 9818f857160f0abd475245e2f4a299ab 153 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 114 127 9.2E-18 T 14-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 LH59_11200 bde4cfe6ee0f1455c5537322a0dce0c9 1060 Gene3D G3DSA:3.30.2090.10 179 275 0.0 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_11200 bde4cfe6ee0f1455c5537322a0dce0c9 1060 SUPERFAMILY SSF82714 724 811 5.36E-23 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_11200 bde4cfe6ee0f1455c5537322a0dce0c9 1060 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 1 1038 0.0 T 14-10-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0006855|GO:0015562|GO:0016021 LH59_11200 bde4cfe6ee0f1455c5537322a0dce0c9 1060 Gene3D G3DSA:3.30.70.1430 568 670 0.0 T 14-10-2018 LH59_11200 bde4cfe6ee0f1455c5537322a0dce0c9 1060 Gene3D G3DSA:1.20.1640.10 8 513 0.0 T 14-10-2018 LH59_11200 bde4cfe6ee0f1455c5537322a0dce0c9 1060 Pfam PF00873 AcrB/AcrD/AcrF family 1 1027 0.0 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_11200 bde4cfe6ee0f1455c5537322a0dce0c9 1060 SUPERFAMILY SSF82693 566 671 6.28E-27 T 14-10-2018 LH59_11200 bde4cfe6ee0f1455c5537322a0dce0c9 1060 SUPERFAMILY SSF82693 135 330 3.49E-26 T 14-10-2018 LH59_11200 bde4cfe6ee0f1455c5537322a0dce0c9 1060 SUPERFAMILY SSF82866 296 497 4.58E-50 T 14-10-2018 LH59_11200 bde4cfe6ee0f1455c5537322a0dce0c9 1060 Gene3D G3DSA:3.30.70.1440 671 867 0.0 T 14-10-2018 LH59_11200 bde4cfe6ee0f1455c5537322a0dce0c9 1060 Gene3D G3DSA:3.30.2090.10 723 811 0.0 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_11200 bde4cfe6ee0f1455c5537322a0dce0c9 1060 PRINTS PR00702 Acriflavin resistance protein family signature 363 384 1.3E-110 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_11200 bde4cfe6ee0f1455c5537322a0dce0c9 1060 PRINTS PR00702 Acriflavin resistance protein family signature 622 636 1.3E-110 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_11200 bde4cfe6ee0f1455c5537322a0dce0c9 1060 PRINTS PR00702 Acriflavin resistance protein family signature 8 32 1.3E-110 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_11200 bde4cfe6ee0f1455c5537322a0dce0c9 1060 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 1.3E-110 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_11200 bde4cfe6ee0f1455c5537322a0dce0c9 1060 PRINTS PR00702 Acriflavin resistance protein family signature 36 54 1.3E-110 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_11200 bde4cfe6ee0f1455c5537322a0dce0c9 1060 PRINTS PR00702 Acriflavin resistance protein family signature 553 570 1.3E-110 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_11200 bde4cfe6ee0f1455c5537322a0dce0c9 1060 PRINTS PR00702 Acriflavin resistance protein family signature 391 415 1.3E-110 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_11200 bde4cfe6ee0f1455c5537322a0dce0c9 1060 PRINTS PR00702 Acriflavin resistance protein family signature 445 468 1.3E-110 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_11200 bde4cfe6ee0f1455c5537322a0dce0c9 1060 PRINTS PR00702 Acriflavin resistance protein family signature 336 359 1.3E-110 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 LH59_11200 bde4cfe6ee0f1455c5537322a0dce0c9 1060 SUPERFAMILY SSF82714 182 271 7.98E-22 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains LH59_11200 bde4cfe6ee0f1455c5537322a0dce0c9 1060 Gene3D G3DSA:3.30.70.1430 38 819 0.0 T 14-10-2018 LH59_11200 bde4cfe6ee0f1455c5537322a0dce0c9 1060 SUPERFAMILY SSF82693 38 131 3.66E-27 T 14-10-2018 LH59_11200 bde4cfe6ee0f1455c5537322a0dce0c9 1060 Gene3D G3DSA:3.30.70.1320 133 332 0.0 T 14-10-2018 LH59_11200 bde4cfe6ee0f1455c5537322a0dce0c9 1060 SUPERFAMILY SSF82866 809 1030 1.31E-46 T 14-10-2018 LH59_11200 bde4cfe6ee0f1455c5537322a0dce0c9 1060 Gene3D G3DSA:1.20.1640.10 514 1024 0.0 T 14-10-2018 LH59_12720 749ad0be9c32cc3069957ab23e91ff0e 563 SMART SM00283 263 510 2.8E-80 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 LH59_12720 749ad0be9c32cc3069957ab23e91ff0e 563 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 324 476 3.5E-48 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 LH59_12720 749ad0be9c32cc3069957ab23e91ff0e 563 SUPERFAMILY SSF58104 230 511 3.66E-67 T 14-10-2018 LH59_12720 749ad0be9c32cc3069957ab23e91ff0e 563 Pfam PF00672 HAMP domain 210 258 9.5E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_12720 749ad0be9c32cc3069957ab23e91ff0e 563 Gene3D G3DSA:1.10.287.950 210 512 1.5E-83 T 14-10-2018 LH59_12720 749ad0be9c32cc3069957ab23e91ff0e 563 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 390 419 6.0E-48 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_12720 749ad0be9c32cc3069957ab23e91ff0e 563 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 284 313 6.0E-48 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_12720 749ad0be9c32cc3069957ab23e91ff0e 563 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 55 70 6.0E-48 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_12720 749ad0be9c32cc3069957ab23e91ff0e 563 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 361 388 6.0E-48 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_12720 749ad0be9c32cc3069957ab23e91ff0e 563 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 438 467 6.0E-48 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_12720 749ad0be9c32cc3069957ab23e91ff0e 563 Pfam PF02203 Tar ligand binding domain homologue 3 163 6.1E-13 T 14-10-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 LH59_12720 749ad0be9c32cc3069957ab23e91ff0e 563 SMART SM00304 210 262 7.6E-12 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_01330 0af063077a7af8b051ed14c71e174906 315 SUPERFAMILY SSF53850 100 307 1.99E-39 T 14-10-2018 LH59_01330 0af063077a7af8b051ed14c71e174906 315 Gene3D G3DSA:3.40.190.290 102 304 5.8E-53 T 14-10-2018 LH59_01330 0af063077a7af8b051ed14c71e174906 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 41 2.5E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_01330 0af063077a7af8b051ed14c71e174906 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 51 62 2.5E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_01330 0af063077a7af8b051ed14c71e174906 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 51 2.5E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_01330 0af063077a7af8b051ed14c71e174906 315 Pfam PF03466 LysR substrate binding domain 99 304 5.7E-37 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_01330 0af063077a7af8b051ed14c71e174906 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 17 74 1.5E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_01330 0af063077a7af8b051ed14c71e174906 315 Gene3D G3DSA:1.10.10.10 15 98 2.3E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_01330 0af063077a7af8b051ed14c71e174906 315 SUPERFAMILY SSF46785 17 122 3.3E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_26035 6e6944e7c80a55d060df33ec5d10719f 201 Pfam PF13417 Glutathione S-transferase, N-terminal domain 4 77 7.5E-16 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 LH59_26035 6e6944e7c80a55d060df33ec5d10719f 201 Gene3D G3DSA:1.20.1050.10 82 191 7.9E-67 T 14-10-2018 LH59_26035 6e6944e7c80a55d060df33ec5d10719f 201 SUPERFAMILY SSF47616 73 199 2.42E-14 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily LH59_26035 6e6944e7c80a55d060df33ec5d10719f 201 Gene3D G3DSA:3.40.30.10 4 193 7.9E-67 T 14-10-2018 LH59_26035 6e6944e7c80a55d060df33ec5d10719f 201 SUPERFAMILY SSF52833 1 77 8.24E-16 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_26035 6e6944e7c80a55d060df33ec5d10719f 201 Pfam PF13410 Glutathione S-transferase, C-terminal domain 124 187 7.5E-6 T 14-10-2018 LH59_10845 82a879a432c7b76e5d522df80346c764 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 57 2.2E-14 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_10845 82a879a432c7b76e5d522df80346c764 193 ProSitePatterns PS01081 TetR-type HTH domain signature. 23 53 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site LH59_10845 82a879a432c7b76e5d522df80346c764 193 Gene3D G3DSA:1.10.10.60 1 64 9.5E-25 T 14-10-2018 LH59_10845 82a879a432c7b76e5d522df80346c764 193 SUPERFAMILY SSF48498 76 178 2.45E-26 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily LH59_10845 82a879a432c7b76e5d522df80346c764 193 Pfam PF16925 Bacterial transcriptional repressor C-terminal 94 165 7.7E-9 T 14-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal LH59_10845 82a879a432c7b76e5d522df80346c764 193 Gene3D G3DSA:1.10.357.10 65 193 2.4E-29 T 14-10-2018 LH59_10845 82a879a432c7b76e5d522df80346c764 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 6.6E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_10845 82a879a432c7b76e5d522df80346c764 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 6.6E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_10845 82a879a432c7b76e5d522df80346c764 193 SUPERFAMILY SSF46689 5 73 4.1E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_04875 245248fc99b32f89a99a852728d3a0da 514 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 20 211 1.2E-14 T 14-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 LH59_04875 245248fc99b32f89a99a852728d3a0da 514 Gene3D G3DSA:3.40.920.10 10 222 2.1E-6 T 14-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 LH59_04875 245248fc99b32f89a99a852728d3a0da 514 SUPERFAMILY SSF53323 13 234 3.4E-8 T 14-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 LH59_11670 52ade88c278abb8df0a9d637c58c333a 285 Pfam PF01148 Cytidylyltransferase family 4 280 4.8E-53 T 14-10-2018 LH59_11670 52ade88c278abb8df0a9d637c58c333a 285 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 242 268 - T 14-10-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 LH59_05720 0a854ab169565e18bceb900a3000cde4 325 Gene3D G3DSA:3.90.180.10 13 323 4.3E-105 T 14-10-2018 LH59_05720 0a854ab169565e18bceb900a3000cde4 325 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 1 325 2.6E-146 T 14-10-2018 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 LH59_05720 0a854ab169565e18bceb900a3000cde4 325 SUPERFAMILY SSF51735 111 287 8.34E-50 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_05720 0a854ab169565e18bceb900a3000cde4 325 SUPERFAMILY SSF50129 1 137 1.67E-36 T 14-10-2018 IPR011032 GroES-like superfamily LH59_05720 0a854ab169565e18bceb900a3000cde4 325 SMART SM00829 10 323 6.5E-51 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 LH59_05720 0a854ab169565e18bceb900a3000cde4 325 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 87 3.3E-5 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 LH59_05720 0a854ab169565e18bceb900a3000cde4 325 Gene3D G3DSA:3.40.50.720 120 262 4.3E-105 T 14-10-2018 LH59_05720 0a854ab169565e18bceb900a3000cde4 325 Pfam PF00107 Zinc-binding dehydrogenase 151 277 9.2E-31 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 LH59_00405 1fbfc55191eaca26ae291d4ca6611d2e 397 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 216 253 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LH59_00405 1fbfc55191eaca26ae291d4ca6611d2e 397 Pfam PF00202 Aminotransferase class-III 20 388 3.6E-101 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LH59_00405 1fbfc55191eaca26ae291d4ca6611d2e 397 Gene3D G3DSA:3.90.1150.10 19 384 3.1E-127 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_00405 1fbfc55191eaca26ae291d4ca6611d2e 397 SUPERFAMILY SSF53383 14 391 2.29E-110 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_00405 1fbfc55191eaca26ae291d4ca6611d2e 397 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 10 394 64.906 T 14-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 LH59_00405 1fbfc55191eaca26ae291d4ca6611d2e 397 PIRSF PIRSF000521 19 394 4.5E-39 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LH59_00405 1fbfc55191eaca26ae291d4ca6611d2e 397 Gene3D G3DSA:3.40.640.10 54 297 3.1E-127 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_21330 3a460cfabf23eac7f5f5ff06f521cae3 263 Gene3D G3DSA:3.90.226.10 1 207 6.4E-58 T 14-10-2018 LH59_21330 3a460cfabf23eac7f5f5ff06f521cae3 263 SUPERFAMILY SSF52096 7 262 1.87E-64 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily LH59_21330 3a460cfabf23eac7f5f5ff06f521cae3 263 Pfam PF00378 Enoyl-CoA hydratase/isomerase 16 261 4.4E-41 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 LH59_21330 3a460cfabf23eac7f5f5ff06f521cae3 263 Gene3D G3DSA:1.10.12.10 208 263 4.3E-12 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal LH59_12690 26282750f6de1ec24def226f49daf9c8 498 Gene3D G3DSA:3.40.50.1580 187 498 4.9E-101 T 14-10-2018 LH59_12690 26282750f6de1ec24def226f49daf9c8 498 Pfam PF01048 Phosphorylase superfamily 276 443 1.7E-13 T 14-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 LH59_12690 26282750f6de1ec24def226f49daf9c8 498 Gene3D G3DSA:3.30.1730.10 21 185 3.2E-48 T 14-10-2018 IPR037109 AMP nucleoside phosphorylase, N-terminal domain superfamily KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 LH59_12690 26282750f6de1ec24def226f49daf9c8 498 Hamap MF_01932 AMP nucleosidase [amn]. 17 498 61.794 T 14-10-2018 IPR011271 AMP nucleosidase GO:0008714|GO:0009116|GO:0044209 KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 LH59_12690 26282750f6de1ec24def226f49daf9c8 498 TIGRFAM TIGR01717 AMP-nucleosdse: AMP nucleosidase 26 498 1.2E-210 T 14-10-2018 IPR011271 AMP nucleosidase GO:0008714|GO:0009116|GO:0044209 KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 LH59_12690 26282750f6de1ec24def226f49daf9c8 498 Pfam PF10423 Bacterial AMP nucleoside phosphorylase N-terminus 26 181 1.3E-53 T 14-10-2018 IPR018953 AMP nucleoside phosphorylase, N-terminal KEGG: 00230+3.2.2.4|MetaCyc: PWY-6617 LH59_12690 26282750f6de1ec24def226f49daf9c8 498 SUPERFAMILY SSF53167 23 498 1.83E-153 T 14-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 LH59_22615 8d3b1ce8ebb43d2ac40b2adf0c699b93 388 SUPERFAMILY SSF52151 1 256 1.1E-47 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase LH59_22615 8d3b1ce8ebb43d2ac40b2adf0c699b93 388 Pfam PF01734 Patatin-like phospholipase 1 223 1.6E-20 T 14-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 LH59_22615 8d3b1ce8ebb43d2ac40b2adf0c699b93 388 Gene3D G3DSA:3.40.1090.10 1 120 3.7E-18 T 14-10-2018 LH59_20905 a2e9a0d311001e8e3b7d4d4d51abd974 141 Pfam PF02566 OsmC-like protein 41 138 1.5E-15 T 14-10-2018 IPR003718 OsmC/Ohr family LH59_20905 a2e9a0d311001e8e3b7d4d4d51abd974 141 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 9 139 2.0E-44 T 14-10-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 LH59_20905 a2e9a0d311001e8e3b7d4d4d51abd974 141 SUPERFAMILY SSF82784 5 139 3.93E-37 T 14-10-2018 IPR036102 OsmC/Ohr superfamily LH59_20905 a2e9a0d311001e8e3b7d4d4d51abd974 141 Gene3D G3DSA:3.30.300.20 46 140 3.2E-30 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta LH59_20905 a2e9a0d311001e8e3b7d4d4d51abd974 141 Gene3D G3DSA:2.20.25.10 1 45 6.2E-17 T 14-10-2018 LH59_02730 22a9fbc790f58026001edb9ac7863bf2 350 SUPERFAMILY SSF51182 11 348 1.34E-114 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_02730 22a9fbc790f58026001edb9ac7863bf2 350 Gene3D G3DSA:2.60.120.10 8 350 4.4E-129 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_02730 22a9fbc790f58026001edb9ac7863bf2 350 Pfam PF07883 Cupin domain 94 165 4.9E-24 T 14-10-2018 IPR013096 Cupin 2, conserved barrel LH59_02730 22a9fbc790f58026001edb9ac7863bf2 350 TIGRFAM TIGR02272 gentisate_1_2: gentisate 1,2-dioxygenase 10 348 5.9E-174 T 14-10-2018 IPR011960 Gentisate 1,2-dioxygenase LH59_02170 7987d4dddb8d6c79910f86cc33eb802a 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 73 2.3E-16 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_02170 7987d4dddb8d6c79910f86cc33eb802a 207 Gene3D G3DSA:1.10.10.60 14 69 1.7E-18 T 14-10-2018 LH59_02170 7987d4dddb8d6c79910f86cc33eb802a 207 SUPERFAMILY SSF48498 97 206 1.26E-20 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily LH59_02170 7987d4dddb8d6c79910f86cc33eb802a 207 Gene3D G3DSA:1.10.357.10 70 206 5.3E-33 T 14-10-2018 LH59_02170 7987d4dddb8d6c79910f86cc33eb802a 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 7.5E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_02170 7987d4dddb8d6c79910f86cc33eb802a 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 7.5E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_02170 7987d4dddb8d6c79910f86cc33eb802a 207 ProSitePatterns PS01081 TetR-type HTH domain signature. 39 69 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site LH59_02170 7987d4dddb8d6c79910f86cc33eb802a 207 SUPERFAMILY SSF46689 21 92 1.9E-17 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_23045 15edc4ead41eb18daa4713bd046eabdd 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 1.6E-21 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_23045 15edc4ead41eb18daa4713bd046eabdd 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 2.4E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_23045 15edc4ead41eb18daa4713bd046eabdd 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 2.4E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_23045 15edc4ead41eb18daa4713bd046eabdd 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 2.4E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_23045 15edc4ead41eb18daa4713bd046eabdd 308 SUPERFAMILY SSF53850 95 298 8.81E-45 T 14-10-2018 LH59_23045 15edc4ead41eb18daa4713bd046eabdd 308 Pfam PF03466 LysR substrate binding domain 92 296 6.4E-45 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_23045 15edc4ead41eb18daa4713bd046eabdd 308 SUPERFAMILY SSF46785 5 116 2.03E-25 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_23045 15edc4ead41eb18daa4713bd046eabdd 308 Gene3D G3DSA:3.40.190.290 96 301 6.7E-51 T 14-10-2018 LH59_23045 15edc4ead41eb18daa4713bd046eabdd 308 Gene3D G3DSA:1.10.10.10 6 94 1.8E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_03190 03ccd9cbdbd5c36b710bfe10f5371f69 470 Pfam PF13719 zinc-ribbon domain 3 38 2.5E-13 T 14-10-2018 IPR011723 Zinc finger/thioredoxin putative LH59_03190 03ccd9cbdbd5c36b710bfe10f5371f69 470 Pfam PF11906 Protein of unknown function (DUF3426) 317 466 2.1E-44 T 14-10-2018 IPR021834 Protein of unknown function DUF3426 LH59_03190 03ccd9cbdbd5c36b710bfe10f5371f69 470 TIGRFAM TIGR02098 MJ0042_CXXC: MJ0042 family finger-like domain 4 39 2.9E-13 T 14-10-2018 IPR011723 Zinc finger/thioredoxin putative LH59_22020 7f9338c0a8012a82fce309c13a04f26c 121 SUPERFAMILY SSF52172 7 120 5.27E-28 T 14-10-2018 IPR011006 CheY-like superfamily LH59_22020 7f9338c0a8012a82fce309c13a04f26c 121 Gene3D G3DSA:3.40.50.2300 2 121 7.7E-28 T 14-10-2018 LH59_22020 7f9338c0a8012a82fce309c13a04f26c 121 SMART SM00448 7 117 1.1E-20 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_22020 7f9338c0a8012a82fce309c13a04f26c 121 Pfam PF00072 Response regulator receiver domain 9 117 1.0E-17 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_14380 db6cf20e42f20302abf57839f22fa8d8 328 Gene3D G3DSA:3.40.190.10 129 253 3.8E-116 T 14-10-2018 LH59_14380 db6cf20e42f20302abf57839f22fa8d8 328 Gene3D G3DSA:3.40.190.150 32 317 3.8E-116 T 14-10-2018 LH59_14380 db6cf20e42f20302abf57839f22fa8d8 328 SUPERFAMILY SSF53850 114 289 3.62E-15 T 14-10-2018 LH59_14380 db6cf20e42f20302abf57839f22fa8d8 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 325 4.7E-96 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_14380 db6cf20e42f20302abf57839f22fa8d8 328 PIRSF PIRSF017082 1 328 1.8E-86 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_23310 a57ea58245846f7dd49b5d10d4203d18 205 Gene3D G3DSA:3.40.30.10 48 204 6.0E-52 T 14-10-2018 LH59_23310 a57ea58245846f7dd49b5d10d4203d18 205 SUPERFAMILY SSF52833 51 204 2.08E-48 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_23310 a57ea58245846f7dd49b5d10d4203d18 205 Pfam PF02630 SCO1/SenC 48 188 9.3E-41 T 14-10-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_26730 74f8e808560faa5813f1541a421afea5 499 PIRSF PIRSF002457 5 499 5.7E-130 T 14-10-2018 IPR030676 Citrate carrier CitT-related LH59_26730 74f8e808560faa5813f1541a421afea5 499 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 38 493 4.6E-71 T 14-10-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 LH59_26730 74f8e808560faa5813f1541a421afea5 499 Pfam PF00939 Sodium:sulfate symporter transmembrane region 23 499 2.8E-127 T 14-10-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 LH59_04995 c9993325d000d433bb3e2b31cc5ea32d 233 SMART SM00448 6 117 1.8E-38 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_04995 c9993325d000d433bb3e2b31cc5ea32d 233 Pfam PF00072 Response regulator receiver domain 9 118 3.9E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_04995 c9993325d000d433bb3e2b31cc5ea32d 233 SUPERFAMILY SSF46894 137 231 4.82E-25 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LH59_04995 c9993325d000d433bb3e2b31cc5ea32d 233 SUPERFAMILY SSF52172 4 129 8.82E-41 T 14-10-2018 IPR011006 CheY-like superfamily LH59_04995 c9993325d000d433bb3e2b31cc5ea32d 233 Gene3D G3DSA:3.40.50.2300 1 123 4.0E-36 T 14-10-2018 LH59_04995 c9993325d000d433bb3e2b31cc5ea32d 233 SMART SM00862 154 231 3.1E-24 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_04995 c9993325d000d433bb3e2b31cc5ea32d 233 Gene3D G3DSA:1.10.10.10 124 233 2.9E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_04995 c9993325d000d433bb3e2b31cc5ea32d 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 231 2.7E-21 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_01875 935f84c0f0f69fb394b5edd44e969386 119 TIGRFAM TIGR00526 folB_dom: FolB domain 5 117 6.8E-20 T 14-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 LH59_01875 935f84c0f0f69fb394b5edd44e969386 119 SUPERFAMILY SSF55620 3 119 6.12E-30 T 14-10-2018 LH59_01875 935f84c0f0f69fb394b5edd44e969386 119 SMART SM00905 6 117 9.9E-32 T 14-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 LH59_01875 935f84c0f0f69fb394b5edd44e969386 119 Pfam PF02152 Dihydroneopterin aldolase 6 116 5.5E-29 T 14-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 LH59_01875 935f84c0f0f69fb394b5edd44e969386 119 Gene3D G3DSA:3.30.1130.10 1 119 6.3E-37 T 14-10-2018 LH59_01875 935f84c0f0f69fb394b5edd44e969386 119 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 5 116 4.2E-25 T 14-10-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 LH59_13905 36ec5853381cc9de5348890a550e63b1 517 SUPERFAMILY SSF53850 32 497 1.33E-125 T 14-10-2018 LH59_13905 36ec5853381cc9de5348890a550e63b1 517 Gene3D G3DSA:3.10.105.10 274 481 5.7E-57 T 14-10-2018 LH59_13905 36ec5853381cc9de5348890a550e63b1 517 Gene3D G3DSA:3.40.190.10 12 273 2.2E-61 T 14-10-2018 LH59_13905 36ec5853381cc9de5348890a550e63b1 517 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 79 429 1.6E-91 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain LH59_13905 36ec5853381cc9de5348890a550e63b1 517 PIRSF PIRSF002741 1 505 1.9E-107 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 LH59_20925 66d7fa1f73533e0a5f3d62acbf7720f4 327 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 235 319 1.6E-24 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_20925 66d7fa1f73533e0a5f3d62acbf7720f4 327 SMART SM00382 36 235 4.3E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_20925 66d7fa1f73533e0a5f3d62acbf7720f4 327 Pfam PF00005 ABC transporter 28 185 8.7E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_20925 66d7fa1f73533e0a5f3d62acbf7720f4 327 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_20925 66d7fa1f73533e0a5f3d62acbf7720f4 327 Gene3D G3DSA:3.40.50.300 6 324 1.7E-99 T 14-10-2018 LH59_20925 66d7fa1f73533e0a5f3d62acbf7720f4 327 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 237 301 5.2E-20 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_20925 66d7fa1f73533e0a5f3d62acbf7720f4 327 SUPERFAMILY SSF52540 8 255 9.52E-67 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_18010 7f2d79b5bb3077bdeb0a7a6abde9b46e 331 Gene3D G3DSA:3.40.190.10 133 256 6.8E-115 T 14-10-2018 LH59_18010 7f2d79b5bb3077bdeb0a7a6abde9b46e 331 Gene3D G3DSA:3.40.190.150 36 321 6.8E-115 T 14-10-2018 LH59_18010 7f2d79b5bb3077bdeb0a7a6abde9b46e 331 SUPERFAMILY SSF53850 117 293 5.07E-14 T 14-10-2018 LH59_18010 7f2d79b5bb3077bdeb0a7a6abde9b46e 331 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 55 323 1.6E-90 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_18010 7f2d79b5bb3077bdeb0a7a6abde9b46e 331 PIRSF PIRSF017082 1 331 3.8E-79 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_04655 f2a3540c20fb37dd4991bfd57194164c 296 Gene3D G3DSA:3.40.190.10 92 284 1.1E-56 T 14-10-2018 LH59_04655 f2a3540c20fb37dd4991bfd57194164c 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 6.0E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_04655 f2a3540c20fb37dd4991bfd57194164c 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 6.0E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_04655 f2a3540c20fb37dd4991bfd57194164c 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 6.0E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_04655 f2a3540c20fb37dd4991bfd57194164c 296 Gene3D G3DSA:1.10.10.10 1 86 5.9E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_04655 f2a3540c20fb37dd4991bfd57194164c 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 1.4E-22 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_04655 f2a3540c20fb37dd4991bfd57194164c 296 SUPERFAMILY SSF53850 90 293 4.46E-34 T 14-10-2018 LH59_04655 f2a3540c20fb37dd4991bfd57194164c 296 Gene3D G3DSA:3.40.190.10 164 268 1.1E-56 T 14-10-2018 LH59_04655 f2a3540c20fb37dd4991bfd57194164c 296 Pfam PF03466 LysR substrate binding domain 89 289 1.2E-37 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_04655 f2a3540c20fb37dd4991bfd57194164c 296 SUPERFAMILY SSF46785 4 88 9.33E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_23480 959adc7c3d3fac072c3c7bc3a887d448 180 Pfam PF02627 Carboxymuconolactone decarboxylase family 50 121 4.9E-13 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 LH59_23480 959adc7c3d3fac072c3c7bc3a887d448 180 TIGRFAM TIGR01926 peroxid_rel: uncharacterized peroxidase-related enzyme 2 170 5.0E-26 T 14-10-2018 IPR010195 Uncharacterised peroxidase-related LH59_23480 959adc7c3d3fac072c3c7bc3a887d448 180 Gene3D G3DSA:1.20.1290.10 13 175 5.8E-46 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 LH59_23480 959adc7c3d3fac072c3c7bc3a887d448 180 SUPERFAMILY SSF69118 1 174 4.11E-54 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 LH59_23480 959adc7c3d3fac072c3c7bc3a887d448 180 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 57 105 1.4E-15 T 14-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 LH59_18405 4c60a7e3955a1bce49d603774925bfd7 510 Gene3D G3DSA:3.40.190.10 38 278 5.0E-127 T 14-10-2018 LH59_18405 4c60a7e3955a1bce49d603774925bfd7 510 Gene3D G3DSA:3.90.76.10 65 179 5.0E-127 T 14-10-2018 LH59_18405 4c60a7e3955a1bce49d603774925bfd7 510 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 74 432 1.7E-93 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain LH59_18405 4c60a7e3955a1bce49d603774925bfd7 510 SUPERFAMILY SSF53850 28 505 3.08E-133 T 14-10-2018 LH59_18405 4c60a7e3955a1bce49d603774925bfd7 510 Gene3D G3DSA:3.10.105.10 279 489 5.0E-127 T 14-10-2018 LH59_18405 4c60a7e3955a1bce49d603774925bfd7 510 PIRSF PIRSF002741 2 509 3.5E-102 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 LH59_15150 6c858f917bc1be2909bba3724353a59a 344 SUPERFAMILY SSF53335 153 329 1.47E-30 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_15150 6c858f917bc1be2909bba3724353a59a 344 Pfam PF16864 Dimerisation domain 21 92 1.5E-7 T 14-10-2018 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain LH59_15150 6c858f917bc1be2909bba3724353a59a 344 Pfam PF00891 O-methyltransferase 173 322 4.5E-14 T 14-10-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 LH59_15150 6c858f917bc1be2909bba3724353a59a 344 Gene3D G3DSA:1.10.10.10 4 85 1.7E-10 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_15150 6c858f917bc1be2909bba3724353a59a 344 Gene3D G3DSA:3.40.50.150 93 324 7.6E-38 T 14-10-2018 LH59_02420 37396d27c5f105671f46d76bea0e546d 244 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 15 219 1.4E-70 T 14-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D LH59_02420 37396d27c5f105671f46d76bea0e546d 244 SUPERFAMILY SSF50891 106 236 4.93E-47 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily LH59_02420 37396d27c5f105671f46d76bea0e546d 244 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 21 229 1.2E-56 T 14-10-2018 IPR010016 KipI family KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 LH59_02420 37396d27c5f105671f46d76bea0e546d 244 SUPERFAMILY SSF160467 16 111 2.62E-16 T 14-10-2018 LH59_02420 37396d27c5f105671f46d76bea0e546d 244 SMART SM00796 15 220 2.5E-91 T 14-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D LH59_02420 37396d27c5f105671f46d76bea0e546d 244 Gene3D G3DSA:3.30.1360.40 16 96 1.6E-18 T 14-10-2018 LH59_02420 37396d27c5f105671f46d76bea0e546d 244 Gene3D G3DSA:2.40.100.10 105 243 1.5E-57 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily LH59_24225 93b63f5c7e34b7f60cbefecd9a5bf338 549 ProSitePatterns PS00455 Putative AMP-binding domain signature. 191 202 - T 14-10-2018 IPR020845 AMP-binding, conserved site LH59_24225 93b63f5c7e34b7f60cbefecd9a5bf338 549 Pfam PF13193 AMP-binding enzyme C-terminal domain 456 531 2.2E-17 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain LH59_24225 93b63f5c7e34b7f60cbefecd9a5bf338 549 Pfam PF00501 AMP-binding enzyme 38 447 4.4E-83 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 LH59_24225 93b63f5c7e34b7f60cbefecd9a5bf338 549 Gene3D G3DSA:3.30.300.310 443 546 8.1E-32 T 14-10-2018 LH59_24225 93b63f5c7e34b7f60cbefecd9a5bf338 549 Gene3D G3DSA:3.40.50.12780 6 442 6.7E-119 T 14-10-2018 LH59_24225 93b63f5c7e34b7f60cbefecd9a5bf338 549 SUPERFAMILY SSF56801 20 543 1.83E-131 T 14-10-2018 LH59_25330 83cb5e55413cc265d2aaed53e16915fe 266 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 53 265 30.281 T 14-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 LH59_25330 83cb5e55413cc265d2aaed53e16915fe 266 Gene3D G3DSA:3.40.50.150 59 266 4.7E-65 T 14-10-2018 LH59_25330 83cb5e55413cc265d2aaed53e16915fe 266 Pfam PF02390 Putative methyltransferase 93 260 1.7E-52 T 14-10-2018 LH59_25330 83cb5e55413cc265d2aaed53e16915fe 266 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 86 265 6.8E-51 T 14-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 LH59_25330 83cb5e55413cc265d2aaed53e16915fe 266 SUPERFAMILY SSF53335 47 264 6.33E-37 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_24820 45d3d103e32c74f71eea662a9abd74db 125 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 123 6.9E-40 T 14-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 LH59_24820 45d3d103e32c74f71eea662a9abd74db 125 Pfam PF01597 Glycine cleavage H-protein 7 122 1.0E-39 T 14-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate LH59_24820 45d3d103e32c74f71eea662a9abd74db 125 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 47 76 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 LH59_24820 45d3d103e32c74f71eea662a9abd74db 125 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 124 36.266 T 14-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 LH59_24820 45d3d103e32c74f71eea662a9abd74db 125 Gene3D G3DSA:2.40.50.100 1 124 5.6E-44 T 14-10-2018 LH59_24820 45d3d103e32c74f71eea662a9abd74db 125 SUPERFAMILY SSF51230 3 123 2.36E-39 T 14-10-2018 IPR011053 Single hybrid motif LH59_08705 f3f1b51ef0a3c1f942f963ff12837d86 1313 Pfam PF11898 Domain of unknown function (DUF3418) 720 1309 6.5E-214 T 14-10-2018 IPR024590 RNA helicase HrpA, C-terminal LH59_08705 f3f1b51ef0a3c1f942f963ff12837d86 1313 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 630 706 6.3E-17 T 14-10-2018 IPR011709 Domain of unknown function DUF1605 LH59_08705 f3f1b51ef0a3c1f942f963ff12837d86 1313 SMART SM00382 66 368 4.3E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_08705 f3f1b51ef0a3c1f942f963ff12837d86 1313 Pfam PF04408 Helicase associated domain (HA2) 465 553 3.0E-15 T 14-10-2018 IPR007502 Helicase-associated domain GO:0004386 LH59_08705 f3f1b51ef0a3c1f942f963ff12837d86 1313 Gene3D G3DSA:3.40.50.300 232 419 3.3E-56 T 14-10-2018 LH59_08705 f3f1b51ef0a3c1f942f963ff12837d86 1313 SMART SM00487 49 238 4.7E-27 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain LH59_08705 f3f1b51ef0a3c1f942f963ff12837d86 1313 SUPERFAMILY SSF52540 49 574 9.51E-99 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_08705 f3f1b51ef0a3c1f942f963ff12837d86 1313 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 35 1309 0.0 T 14-10-2018 IPR010222 RNA helicase HrpA GO:0004004 LH59_08705 f3f1b51ef0a3c1f942f963ff12837d86 1313 SMART SM00847 462 566 3.0E-29 T 14-10-2018 IPR007502 Helicase-associated domain GO:0004386 LH59_08705 f3f1b51ef0a3c1f942f963ff12837d86 1313 Pfam PF00270 DEAD/DEAH box helicase 59 207 9.2E-6 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 LH59_08705 f3f1b51ef0a3c1f942f963ff12837d86 1313 SMART SM00490 301 402 9.2E-20 T 14-10-2018 IPR001650 Helicase, C-terminal LH59_08705 f3f1b51ef0a3c1f942f963ff12837d86 1313 Gene3D G3DSA:1.20.120.1080 444 561 1.2E-15 T 14-10-2018 LH59_08705 f3f1b51ef0a3c1f942f963ff12837d86 1313 Gene3D G3DSA:3.40.50.300 22 231 2.1E-77 T 14-10-2018 LH59_08705 f3f1b51ef0a3c1f942f963ff12837d86 1313 Pfam PF00271 Helicase conserved C-terminal domain 277 402 2.7E-13 T 14-10-2018 IPR001650 Helicase, C-terminal LH59_13310 d0c557fe8196e256ae2880fe5b5a4365 298 Gene3D G3DSA:1.10.10.10 2 91 1.3E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_13310 d0c557fe8196e256ae2880fe5b5a4365 298 SUPERFAMILY SSF46785 8 88 4.54E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_13310 d0c557fe8196e256ae2880fe5b5a4365 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 70 1.3E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_13310 d0c557fe8196e256ae2880fe5b5a4365 298 Pfam PF03466 LysR substrate binding domain 98 297 4.3E-20 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_13310 d0c557fe8196e256ae2880fe5b5a4365 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 27 38 2.6E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_13310 d0c557fe8196e256ae2880fe5b5a4365 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 48 2.6E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_13310 d0c557fe8196e256ae2880fe5b5a4365 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 48 59 2.6E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_13310 d0c557fe8196e256ae2880fe5b5a4365 298 SUPERFAMILY SSF53850 93 293 1.43E-34 T 14-10-2018 LH59_13310 d0c557fe8196e256ae2880fe5b5a4365 298 Gene3D G3DSA:3.40.190.10 174 268 3.9E-57 T 14-10-2018 LH59_13310 d0c557fe8196e256ae2880fe5b5a4365 298 Gene3D G3DSA:3.40.190.10 93 292 3.9E-57 T 14-10-2018 LH59_25110 e95e95a1811f5dfb9a74590d93b4ee84 451 Pfam PF01979 Amidohydrolase family 53 430 4.1E-14 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 LH59_25110 e95e95a1811f5dfb9a74590d93b4ee84 451 SUPERFAMILY SSF51338 8 447 1.64E-24 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 LH59_25110 e95e95a1811f5dfb9a74590d93b4ee84 451 Gene3D G3DSA:2.30.40.10 7 446 7.8E-113 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 LH59_25110 e95e95a1811f5dfb9a74590d93b4ee84 451 Gene3D G3DSA:3.20.20.140 56 417 7.8E-113 T 14-10-2018 LH59_25110 e95e95a1811f5dfb9a74590d93b4ee84 451 SUPERFAMILY SSF51556 56 377 3.54E-67 T 14-10-2018 IPR032466 Metal-dependent hydrolase LH59_10055 f9a73505ae3527ec8d357e5bd8a49a59 415 Gene3D G3DSA:3.50.50.60 3 51 4.8E-11 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_10055 f9a73505ae3527ec8d357e5bd8a49a59 415 SUPERFAMILY SSF51905 1 414 3.11E-45 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_10055 f9a73505ae3527ec8d357e5bd8a49a59 415 Pfam PF01266 FAD dependent oxidoreductase 2 399 2.2E-61 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 LH59_10055 f9a73505ae3527ec8d357e5bd8a49a59 415 Gene3D G3DSA:3.50.50.60 104 399 4.0E-43 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_10055 f9a73505ae3527ec8d357e5bd8a49a59 415 SUPERFAMILY SSF54373 271 361 6.41E-11 T 14-10-2018 LH59_10055 f9a73505ae3527ec8d357e5bd8a49a59 415 Gene3D G3DSA:3.30.9.10 134 360 4.0E-43 T 14-10-2018 LH59_19430 3471e59d90530d6b139bb970da79293f 317 SMART SM00559 54 182 2.0E-27 T 14-10-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 LH59_19430 3471e59d90530d6b139bb970da79293f 317 Gene3D G3DSA:2.40.290.10 4 179 1.0E-15 T 14-10-2018 IPR016194 SPOC-like, C-terminal domain superfamily LH59_19430 3471e59d90530d6b139bb970da79293f 317 PIRSF PIRSF006493 1 315 2.8E-94 T 14-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type LH59_19430 3471e59d90530d6b139bb970da79293f 317 SUPERFAMILY SSF100939 4 263 2.75E-48 T 14-10-2018 IPR016194 SPOC-like, C-terminal domain superfamily LH59_19430 3471e59d90530d6b139bb970da79293f 317 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 3 263 30.956 T 14-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type LH59_19430 3471e59d90530d6b139bb970da79293f 317 TIGRFAM TIGR02772 Ku_bact: Ku protein 4 265 4.3E-93 T 14-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type LH59_19430 3471e59d90530d6b139bb970da79293f 317 Pfam PF02735 Ku70/Ku80 beta-barrel domain 13 195 2.2E-33 T 14-10-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 LH59_04435 364cbb87c2b09e826d722514faaa6972 712 SUPERFAMILY SSF109604 355 501 1.05E-10 T 14-10-2018 LH59_04435 364cbb87c2b09e826d722514faaa6972 712 Pfam PF05746 DALR anticodon binding domain 605 703 7.6E-6 T 14-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 LH59_04435 364cbb87c2b09e826d722514faaa6972 712 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 7 710 4.8E-165 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 LH59_04435 364cbb87c2b09e826d722514faaa6972 712 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 9 22 4.5E-31 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 LH59_04435 364cbb87c2b09e826d722514faaa6972 712 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 260 275 4.5E-31 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 LH59_04435 364cbb87c2b09e826d722514faaa6972 712 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 333 349 4.5E-31 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 LH59_04435 364cbb87c2b09e826d722514faaa6972 712 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 54 66 4.5E-31 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 LH59_04435 364cbb87c2b09e826d722514faaa6972 712 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 409 428 4.5E-31 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 LH59_04435 364cbb87c2b09e826d722514faaa6972 712 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 8 574 8.7E-174 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 LH59_04435 364cbb87c2b09e826d722514faaa6972 712 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 5 710 21.711 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 LH59_17635 3db3dfc86af1d8b89c1d14510310f9d2 876 Gene3D G3DSA:3.55.50.30 30 132 4.5E-23 T 14-10-2018 LH59_17635 3db3dfc86af1d8b89c1d14510310f9d2 876 Pfam PF07715 TonB-dependent Receptor Plug Domain 134 251 1.4E-8 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_17635 3db3dfc86af1d8b89c1d14510310f9d2 876 SUPERFAMILY SSF56935 119 876 3.11E-54 T 14-10-2018 LH59_17635 3db3dfc86af1d8b89c1d14510310f9d2 876 Gene3D G3DSA:2.40.170.20 315 876 8.0E-27 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_17635 3db3dfc86af1d8b89c1d14510310f9d2 876 SMART SM00965 59 110 4.0E-10 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 LH59_25980 785b92d03e011990050bd948a944bded 216 Pfam PF00484 Carbonic anhydrase 37 195 4.6E-47 T 14-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 LH59_25980 785b92d03e011990050bd948a944bded 216 SMART SM00947 30 200 1.6E-63 T 14-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 LH59_25980 785b92d03e011990050bd948a944bded 216 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 89 109 - T 14-10-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 LH59_25980 785b92d03e011990050bd948a944bded 216 Gene3D G3DSA:3.40.1050.10 2 204 7.9E-65 T 14-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 LH59_25980 785b92d03e011990050bd948a944bded 216 SUPERFAMILY SSF53056 3 209 7.33E-58 T 14-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 LH59_08930 b372aa2467e20c05383afd0f2dd95877 485 Gene3D G3DSA:3.40.605.10 20 479 3.3E-187 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 LH59_08930 b372aa2467e20c05383afd0f2dd95877 485 Pfam PF00171 Aldehyde dehydrogenase family 18 481 3.1E-174 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 LH59_08930 b372aa2467e20c05383afd0f2dd95877 485 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 257 264 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 LH59_08930 b372aa2467e20c05383afd0f2dd95877 485 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 285 296 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 LH59_08930 b372aa2467e20c05383afd0f2dd95877 485 Gene3D G3DSA:3.40.309.10 261 450 3.3E-187 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 LH59_08930 b372aa2467e20c05383afd0f2dd95877 485 SUPERFAMILY SSF53720 7 483 5.89E-170 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 LH59_02620 832da22b82c54d0c166a940f8a159580 323 SUPERFAMILY SSF52317 1 195 9.36E-49 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_02620 832da22b82c54d0c166a940f8a159580 323 Gene3D G3DSA:1.10.10.60 211 316 9.5E-26 T 14-10-2018 LH59_02620 832da22b82c54d0c166a940f8a159580 323 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 267 309 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 LH59_02620 832da22b82c54d0c166a940f8a159580 323 Pfam PF12833 Helix-turn-helix domain 236 314 7.6E-21 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_02620 832da22b82c54d0c166a940f8a159580 323 SMART SM00342 230 313 7.1E-25 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_02620 832da22b82c54d0c166a940f8a159580 323 SUPERFAMILY SSF46689 267 316 3.99E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_02620 832da22b82c54d0c166a940f8a159580 323 Gene3D G3DSA:3.40.50.880 1 210 1.3E-59 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_02620 832da22b82c54d0c166a940f8a159580 323 Pfam PF01965 DJ-1/PfpI family 2 175 9.7E-24 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 LH59_02620 832da22b82c54d0c166a940f8a159580 323 SUPERFAMILY SSF46689 215 263 2.06E-7 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_06185 d43df71b0b5d44fbf3cd85467cfe6f9d 285 Pfam PF12710 haloacid dehalogenase-like hydrolase 81 248 6.2E-19 T 14-10-2018 LH59_06185 d43df71b0b5d44fbf3cd85467cfe6f9d 285 Pfam PF13284 Domain of unknown function (DUF4072) 6 53 4.8E-14 T 14-10-2018 IPR025138 Domain of unknown function DUF4072 LH59_06185 d43df71b0b5d44fbf3cd85467cfe6f9d 285 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 74 280 2.0E-69 T 14-10-2018 LH59_06185 d43df71b0b5d44fbf3cd85467cfe6f9d 285 SUPERFAMILY SSF56784 75 284 4.0E-48 T 14-10-2018 IPR036412 HAD-like superfamily LH59_06185 d43df71b0b5d44fbf3cd85467cfe6f9d 285 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 79 249 1.6E-32 T 14-10-2018 LH59_06185 d43df71b0b5d44fbf3cd85467cfe6f9d 285 Gene3D G3DSA:3.40.50.1000 8 284 1.0E-70 T 14-10-2018 IPR023214 HAD superfamily LH59_23970 d0d6374f37d42d88ca07cc292f28fe6d 219 SMART SM00450 118 213 4.9E-20 T 14-10-2018 IPR001763 Rhodanese-like domain LH59_23970 d0d6374f37d42d88ca07cc292f28fe6d 219 SUPERFAMILY SSF46785 9 109 8.03E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_23970 d0d6374f37d42d88ca07cc292f28fe6d 219 SUPERFAMILY SSF52821 113 214 2.23E-31 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily LH59_23970 d0d6374f37d42d88ca07cc292f28fe6d 219 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 63 78 1.6E-6 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LH59_23970 d0d6374f37d42d88ca07cc292f28fe6d 219 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 16 31 1.6E-6 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LH59_23970 d0d6374f37d42d88ca07cc292f28fe6d 219 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 48 63 1.6E-6 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LH59_23970 d0d6374f37d42d88ca07cc292f28fe6d 219 Pfam PF12840 Helix-turn-helix domain 14 71 4.6E-11 T 14-10-2018 LH59_23970 d0d6374f37d42d88ca07cc292f28fe6d 219 Gene3D G3DSA:1.10.10.10 2 103 1.2E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_23970 d0d6374f37d42d88ca07cc292f28fe6d 219 ProSitePatterns PS00380 Rhodanese signature 1. 142 153 - T 14-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 LH59_23970 d0d6374f37d42d88ca07cc292f28fe6d 219 SMART SM00418 14 92 3.0E-17 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LH59_23970 d0d6374f37d42d88ca07cc292f28fe6d 219 Pfam PF00581 Rhodanese-like domain 120 210 2.0E-15 T 14-10-2018 IPR001763 Rhodanese-like domain LH59_23970 d0d6374f37d42d88ca07cc292f28fe6d 219 Gene3D G3DSA:3.40.250.10 104 219 1.9E-29 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily LH59_13960 3b37c5ffbf6080bde16e4f27117ba3de 237 Gene3D G3DSA:3.40.50.880 18 227 6.1E-52 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_13960 3b37c5ffbf6080bde16e4f27117ba3de 237 SUPERFAMILY SSF52317 38 204 1.4E-38 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_13960 3b37c5ffbf6080bde16e4f27117ba3de 237 Pfam PF00117 Glutamine amidotransferase class-I 76 197 5.9E-18 T 14-10-2018 IPR017926 Glutamine amidotransferase LH59_13960 3b37c5ffbf6080bde16e4f27117ba3de 237 PRINTS PR00096 Glutamine amidotransferase superfamily signature 183 196 4.7E-5 T 14-10-2018 LH59_13960 3b37c5ffbf6080bde16e4f27117ba3de 237 PRINTS PR00096 Glutamine amidotransferase superfamily signature 92 103 4.7E-5 T 14-10-2018 LH59_19065 fcf350504aa124894e255e3ffd917d08 241 Gene3D G3DSA:3.40.30.10 17 209 1.3E-34 T 14-10-2018 LH59_19065 fcf350504aa124894e255e3ffd917d08 241 Pfam PF13410 Glutathione S-transferase, C-terminal domain 148 182 9.4E-7 T 14-10-2018 LH59_19065 fcf350504aa124894e255e3ffd917d08 241 SUPERFAMILY SSF52833 21 82 2.15E-9 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_19065 fcf350504aa124894e255e3ffd917d08 241 Gene3D G3DSA:1.20.1050.10 88 202 1.3E-34 T 14-10-2018 LH59_19065 fcf350504aa124894e255e3ffd917d08 241 SUPERFAMILY SSF47616 95 212 1.85E-15 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily LH59_19065 fcf350504aa124894e255e3ffd917d08 241 Pfam PF13409 Glutathione S-transferase, N-terminal domain 24 80 1.0E-7 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 LH59_19195 d20c4800ed7323c70ca234e7df23ddb4 425 Gene3D G3DSA:3.20.20.110 136 425 2.5E-102 T 14-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 LH59_19195 d20c4800ed7323c70ca234e7df23ddb4 425 SUPERFAMILY SSF54966 4 135 5.76E-35 T 14-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 LH59_19195 d20c4800ed7323c70ca234e7df23ddb4 425 ProSitePatterns PS00157 Ribulose bisphosphate carboxylase large chain active site. 183 191 - T 14-10-2018 IPR020878 Ribulose bisphosphate carboxylase, large chain, active site GO:0000287|GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 LH59_19195 d20c4800ed7323c70ca234e7df23ddb4 425 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 141 421 2.5E-75 T 14-10-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 LH59_19195 d20c4800ed7323c70ca234e7df23ddb4 425 Gene3D G3DSA:3.30.70.150 1 135 2.2E-44 T 14-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 LH59_19195 d20c4800ed7323c70ca234e7df23ddb4 425 Pfam PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain 16 131 5.5E-6 T 14-10-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 LH59_19195 d20c4800ed7323c70ca234e7df23ddb4 425 SUPERFAMILY SSF51649 135 423 1.3E-86 T 14-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 LH59_24585 7ff4b44e012153dc0b8033eedca3b823 72 Pfam PF10932 Protein of unknown function (DUF2783) 2 59 1.6E-30 T 14-10-2018 IPR021233 Protein of unknown function DUF2783 LH59_06065 cc489d6eea8497317ed5ebf025111d8c 599 SUPERFAMILY SSF56235 5 590 8.3E-143 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal LH59_06065 cc489d6eea8497317ed5ebf025111d8c 599 Gene3D G3DSA:1.10.246.130 263 381 6.0E-33 T 14-10-2018 LH59_06065 cc489d6eea8497317ed5ebf025111d8c 599 Gene3D G3DSA:3.60.20.40 409 598 9.5E-49 T 14-10-2018 LH59_06065 cc489d6eea8497317ed5ebf025111d8c 599 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 463 478 1.4E-26 T 14-10-2018 LH59_06065 cc489d6eea8497317ed5ebf025111d8c 599 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 124 143 1.4E-26 T 14-10-2018 LH59_06065 cc489d6eea8497317ed5ebf025111d8c 599 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 409 427 1.4E-26 T 14-10-2018 LH59_06065 cc489d6eea8497317ed5ebf025111d8c 599 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 35 60 1.4E-26 T 14-10-2018 LH59_06065 cc489d6eea8497317ed5ebf025111d8c 599 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 106 124 1.4E-26 T 14-10-2018 LH59_06065 cc489d6eea8497317ed5ebf025111d8c 599 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 487 504 1.4E-26 T 14-10-2018 LH59_06065 cc489d6eea8497317ed5ebf025111d8c 599 Pfam PF01019 Gamma-glutamyltranspeptidase 28 590 9.3E-125 T 14-10-2018 LH59_21755 e63b029604f87a6ee346cd4e1e590993 219 TIGRFAM TIGR03840 TMPT_Se_Te: thiopurine S-methyltransferase, Se/Te detoxification family 4 215 4.0E-80 T 14-10-2018 IPR022474 Thiopurine S-methyltransferase, Se/Te detoxification GO:0008119|GO:0010038|GO:0032259 KEGG: 00983+2.1.1.67 LH59_21755 e63b029604f87a6ee346cd4e1e590993 219 Pfam PF05724 Thiopurine S-methyltransferase (TPMT) 1 215 9.3E-75 T 14-10-2018 IPR008854 TPMT family GO:0008757 KEGG: 00983+2.1.1.67|Reactome: R-HSA-156581|Reactome: R-HSA-5578995 LH59_21755 e63b029604f87a6ee346cd4e1e590993 219 Hamap MF_00812 Thiopurine S-methyltransferase [tpm]. 1 217 37.924 T 14-10-2018 IPR025835 Thiopurine S-methyltransferase GO:0008119 KEGG: 00983+2.1.1.67|Reactome: R-HSA-156581|Reactome: R-HSA-5578995 LH59_21755 e63b029604f87a6ee346cd4e1e590993 219 SUPERFAMILY SSF53335 1 215 2.64E-56 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_21755 e63b029604f87a6ee346cd4e1e590993 219 PIRSF PIRSF023956 1 219 7.3E-73 T 14-10-2018 IPR025835 Thiopurine S-methyltransferase GO:0008119 KEGG: 00983+2.1.1.67|Reactome: R-HSA-156581|Reactome: R-HSA-5578995 LH59_21755 e63b029604f87a6ee346cd4e1e590993 219 Gene3D G3DSA:3.40.50.150 16 217 5.7E-61 T 14-10-2018 LH59_01365 ff4e48cf4ddaae02f3903321705459ca 348 Pfam PF00491 Arginase family 71 338 7.4E-86 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 LH59_01365 ff4e48cf4ddaae02f3903321705459ca 348 ProSitePatterns PS01053 Arginase family signature. 270 291 - T 14-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 LH59_01365 ff4e48cf4ddaae02f3903321705459ca 348 Gene3D G3DSA:3.40.800.10 33 346 3.1E-103 T 14-10-2018 LH59_01365 ff4e48cf4ddaae02f3903321705459ca 348 SUPERFAMILY SSF52768 64 343 2.52E-87 T 14-10-2018 IPR023696 Ureohydrolase domain superfamily LH59_01365 ff4e48cf4ddaae02f3903321705459ca 348 PIRSF PIRSF036979 48 345 1.1E-97 T 14-10-2018 IPR006035 Ureohydrolase GO:0046872 LH59_01365 ff4e48cf4ddaae02f3903321705459ca 348 TIGRFAM TIGR01230 agmatinase: agmatinase 64 339 1.2E-61 T 14-10-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 LH59_05635 4372e1940e0e04eb53bdf1fd808da3dd 740 Pfam PF13515 Fusaric acid resistance protein-like 421 543 4.8E-16 T 14-10-2018 LH59_05635 4372e1940e0e04eb53bdf1fd808da3dd 740 Pfam PF12805 FUSC-like inner membrane protein yccS 72 352 2.6E-70 T 14-10-2018 IPR032692 Integral membrane protein YccS, N-terminal LH59_11975 fa03def9aa935a5b20d86b2eebbf76ce 138 Pfam PF00472 RF-1 domain 8 132 1.5E-24 T 14-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 LH59_11975 fa03def9aa935a5b20d86b2eebbf76ce 138 SUPERFAMILY SSF75620 7 115 1.14E-13 T 14-10-2018 LH59_11975 fa03def9aa935a5b20d86b2eebbf76ce 138 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 21 37 - T 14-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 LH59_11975 fa03def9aa935a5b20d86b2eebbf76ce 138 Gene3D G3DSA:3.30.160.20 1 138 4.2E-41 T 14-10-2018 LH59_07220 51789923f1dca663b975c4f72453e181 565 SUPERFAMILY SSF53448 73 401 9.19E-10 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases LH59_07220 51789923f1dca663b975c4f72453e181 565 Gene3D G3DSA:3.90.550.10 62 290 5.0E-7 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases LH59_07220 51789923f1dca663b975c4f72453e181 565 Pfam PF13632 Glycosyl transferase family group 2 167 386 5.4E-47 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 LH59_07220 51789923f1dca663b975c4f72453e181 565 SUPERFAMILY SSF160246 491 548 3.4E-10 T 14-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily LH59_19955 55ccf4c325cd137801bd12e186e6d409 469 SUPERFAMILY SSF51735 148 233 2.01E-5 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_19955 55ccf4c325cd137801bd12e186e6d409 469 Pfam PF02397 Bacterial sugar transferase 279 460 1.6E-63 T 14-10-2018 IPR003362 Bacterial sugar transferase LH59_19955 55ccf4c325cd137801bd12e186e6d409 469 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 22 469 3.7E-139 T 14-10-2018 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase LH59_19955 55ccf4c325cd137801bd12e186e6d409 469 Pfam PF13727 CoA-binding domain 67 243 2.8E-36 T 14-10-2018 LH59_19955 55ccf4c325cd137801bd12e186e6d409 469 Gene3D G3DSA:3.40.50.720 146 260 1.1E-10 T 14-10-2018 LH59_19955 55ccf4c325cd137801bd12e186e6d409 469 TIGRFAM TIGR03023 WcaJ_sugtrans: undecaprenyl-phosphate glucose phosphotransferase 22 469 4.3E-155 T 14-10-2018 IPR017473 Undecaprenyl-phosphate glucose phosphotransferase, WcaJ MetaCyc: PWY-6655|MetaCyc: PWY-6658 LH59_00590 57b25d209db38e1ff6f4d355fdbab8e6 110 Hamap MF_00010 UPF0060 membrane protein YnfA [ynfA]. 4 108 24.516 T 14-10-2018 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 LH59_00590 57b25d209db38e1ff6f4d355fdbab8e6 110 Pfam PF02694 Uncharacterised BCR, YnfA/UPF0060 family 3 109 9.8E-40 T 14-10-2018 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 LH59_00590 57b25d209db38e1ff6f4d355fdbab8e6 110 SUPERFAMILY SSF103481 10 107 1.22E-6 T 14-10-2018 LH59_14915 1cc4f3eb36d172f879eb7ebbbb8e5331 210 PIRSF PIRSF000370 1 210 1.9E-35 T 14-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 LH59_14915 1cc4f3eb36d172f879eb7ebbbb8e5331 210 Pfam PF13394 4Fe-4S single cluster domain 25 122 1.8E-5 T 14-10-2018 LH59_14915 1cc4f3eb36d172f879eb7ebbbb8e5331 210 SUPERFAMILY SSF102114 45 137 1.31E-8 T 14-10-2018 LH59_14915 1cc4f3eb36d172f879eb7ebbbb8e5331 210 Gene3D G3DSA:3.20.20.70 2 210 9.3E-70 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_14915 1cc4f3eb36d172f879eb7ebbbb8e5331 210 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 3 210 32.169 T 14-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 LH59_14915 1cc4f3eb36d172f879eb7ebbbb8e5331 210 Pfam PF04055 Radical SAM superfamily 45 122 2.2E-7 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 LH59_14915 1cc4f3eb36d172f879eb7ebbbb8e5331 210 TIGRFAM TIGR04508 queE_Cx14CxxC: 7-carboxy-7-deazaguanine synthase 3 210 4.6E-107 T 14-10-2018 IPR030977 7-carboxy-7-deazaguanine synthase, Cx14CxxC-type GO:0008616|GO:0046872 KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 LH59_12680 de5c28500ce87aa21f94923ea9fdf58f 683 Gene3D G3DSA:2.170.130.10 44 160 7.9E-26 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily LH59_12680 de5c28500ce87aa21f94923ea9fdf58f 683 Pfam PF00593 TonB dependent receptor 236 680 1.1E-43 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_12680 de5c28500ce87aa21f94923ea9fdf58f 683 Pfam PF07715 TonB-dependent Receptor Plug Domain 48 150 4.2E-16 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_12680 de5c28500ce87aa21f94923ea9fdf58f 683 SUPERFAMILY SSF56935 39 683 2.34E-90 T 14-10-2018 LH59_12680 de5c28500ce87aa21f94923ea9fdf58f 683 Gene3D G3DSA:2.40.170.20 162 683 7.5E-67 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_24775 1a1abd2396d7683d3932b1aaed670248 521 PIRSF PIRSF002741 17 520 3.0E-63 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 LH59_24775 1a1abd2396d7683d3932b1aaed670248 521 Gene3D G3DSA:3.40.190.10 184 505 1.8E-91 T 14-10-2018 LH59_24775 1a1abd2396d7683d3932b1aaed670248 521 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 67 443 7.0E-88 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain LH59_24775 1a1abd2396d7683d3932b1aaed670248 521 Gene3D G3DSA:3.10.105.10 269 496 1.8E-91 T 14-10-2018 LH59_24775 1a1abd2396d7683d3932b1aaed670248 521 SUPERFAMILY SSF53850 23 516 4.89E-102 T 14-10-2018 LH59_24775 1a1abd2396d7683d3932b1aaed670248 521 Gene3D G3DSA:3.90.76.10 38 183 1.8E-91 T 14-10-2018 LH59_19680 e0dc7e0910f860be7bb0f0732ff15a87 327 Gene3D G3DSA:3.40.190.150 30 316 1.1E-106 T 14-10-2018 LH59_19680 e0dc7e0910f860be7bb0f0732ff15a87 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 322 2.9E-80 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_19680 e0dc7e0910f860be7bb0f0732ff15a87 327 PIRSF PIRSF017082 2 326 2.6E-72 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_19680 e0dc7e0910f860be7bb0f0732ff15a87 327 SUPERFAMILY SSF53850 111 284 9.77E-10 T 14-10-2018 LH59_19680 e0dc7e0910f860be7bb0f0732ff15a87 327 Gene3D G3DSA:3.40.190.10 128 251 1.1E-106 T 14-10-2018 LH59_18735 8498e2350dcdc291126baab0bf311391 214 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 12 212 1.7E-60 T 14-10-2018 IPR005744 Hly-III GO:0016021|GO:0019835 LH59_18735 8498e2350dcdc291126baab0bf311391 214 Pfam PF03006 Haemolysin-III related 10 206 3.5E-40 T 14-10-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 LH59_22465 54c274a00bb00b34e5fa884f2af24d01 119 Pfam PF12840 Helix-turn-helix domain 10 69 1.4E-14 T 14-10-2018 LH59_22465 54c274a00bb00b34e5fa884f2af24d01 119 SMART SM00418 11 89 8.8E-16 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LH59_22465 54c274a00bb00b34e5fa884f2af24d01 119 SUPERFAMILY SSF46785 1 104 3.0E-25 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_22465 54c274a00bb00b34e5fa884f2af24d01 119 Gene3D G3DSA:1.10.10.10 4 109 2.6E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_27195 7c6284a7dba6a507d85086eb93369096 444 Gene3D G3DSA:1.10.8.60 336 441 6.3E-36 T 14-10-2018 LH59_27195 7c6284a7dba6a507d85086eb93369096 444 SMART SM01086 336 430 7.2E-18 T 14-10-2018 IPR019489 Clp ATPase, C-terminal LH59_27195 7c6284a7dba6a507d85086eb93369096 444 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 3 444 42.422 T 14-10-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 LH59_27195 7c6284a7dba6a507d85086eb93369096 444 Pfam PF07724 AAA domain (Cdc48 subfamily) 190 330 1.0E-39 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 LH59_27195 7c6284a7dba6a507d85086eb93369096 444 SMART SM00382 51 333 6.3E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_27195 7c6284a7dba6a507d85086eb93369096 444 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 336 405 1.9E-5 T 14-10-2018 IPR019489 Clp ATPase, C-terminal LH59_27195 7c6284a7dba6a507d85086eb93369096 444 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 55 104 1.4E-6 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 LH59_27195 7c6284a7dba6a507d85086eb93369096 444 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 6 444 2.5E-201 T 14-10-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 LH59_27195 7c6284a7dba6a507d85086eb93369096 444 SUPERFAMILY SSF52540 5 439 2.61E-83 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_00335 2297046c71c195d246d6c2b11b6bcfe1 875 Pfam PF01131 DNA topoisomerase 155 598 2.3E-111 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 LH59_00335 2297046c71c195d246d6c2b11b6bcfe1 875 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 315 330 - T 14-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 LH59_00335 2297046c71c195d246d6c2b11b6bcfe1 875 Gene3D G3DSA:3.40.50.140 3 152 6.3E-42 T 14-10-2018 LH59_00335 2297046c71c195d246d6c2b11b6bcfe1 875 SMART SM00436 125 220 1.6E-22 T 14-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 LH59_00335 2297046c71c195d246d6c2b11b6bcfe1 875 Gene3D G3DSA:1.10.290.10 287 422 1.3E-158 T 14-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 LH59_00335 2297046c71c195d246d6c2b11b6bcfe1 875 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 408 424 5.8E-26 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 LH59_00335 2297046c71c195d246d6c2b11b6bcfe1 875 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 321 330 5.8E-26 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 LH59_00335 2297046c71c195d246d6c2b11b6bcfe1 875 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 523 537 5.8E-26 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 LH59_00335 2297046c71c195d246d6c2b11b6bcfe1 875 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 99 112 5.8E-26 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 LH59_00335 2297046c71c195d246d6c2b11b6bcfe1 875 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 190 208 5.8E-26 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 LH59_00335 2297046c71c195d246d6c2b11b6bcfe1 875 Pfam PF13342 C-terminal repeat of topoisomerase 649 708 3.9E-21 T 14-10-2018 IPR025589 Topoisomerase C-terminal repeat LH59_00335 2297046c71c195d246d6c2b11b6bcfe1 875 Pfam PF13342 C-terminal repeat of topoisomerase 754 814 1.3E-19 T 14-10-2018 IPR025589 Topoisomerase C-terminal repeat LH59_00335 2297046c71c195d246d6c2b11b6bcfe1 875 SMART SM00437 278 560 4.9E-74 T 14-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 LH59_00335 2297046c71c195d246d6c2b11b6bcfe1 875 Gene3D G3DSA:1.10.460.10 159 608 1.3E-158 T 14-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 LH59_00335 2297046c71c195d246d6c2b11b6bcfe1 875 Gene3D G3DSA:2.70.20.10 214 491 1.3E-158 T 14-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 LH59_00335 2297046c71c195d246d6c2b11b6bcfe1 875 SUPERFAMILY SSF56712 3 613 2.35E-167 T 14-10-2018 IPR023405 DNA topoisomerase, type IA, core domain LH59_00335 2297046c71c195d246d6c2b11b6bcfe1 875 TIGRFAM TIGR01056 topB: DNA topoisomerase III 3 619 5.2E-168 T 14-10-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 LH59_00335 2297046c71c195d246d6c2b11b6bcfe1 875 Pfam PF01751 Toprim domain 4 131 2.2E-12 T 14-10-2018 IPR006171 TOPRIM domain LH59_00335 2297046c71c195d246d6c2b11b6bcfe1 875 SMART SM00493 3 125 1.4E-16 T 14-10-2018 IPR006171 TOPRIM domain LH59_18985 5c61388939599fc287c156abdd407762 121 SUPERFAMILY SSF51182 19 119 8.13E-17 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_18985 5c61388939599fc287c156abdd407762 121 Gene3D G3DSA:2.60.120.10 17 120 4.7E-30 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_18985 5c61388939599fc287c156abdd407762 121 Pfam PF05899 Protein of unknown function (DUF861) 42 115 1.4E-15 T 14-10-2018 IPR008579 Domain of unknown function DUF861, cupin-3 KEGG: 00230+3.5.3.26|MetaCyc: PWY-5692|MetaCyc: PWY-5698 LH59_06095 563c27481b2c462b5ca5cb5a5d607fd2 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 67 1.5E-12 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_06095 563c27481b2c462b5ca5cb5a5d607fd2 204 Gene3D G3DSA:1.10.357.10 5 203 1.4E-25 T 14-10-2018 LH59_06095 563c27481b2c462b5ca5cb5a5d607fd2 204 SUPERFAMILY SSF46689 11 89 5.49E-18 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_06095 563c27481b2c462b5ca5cb5a5d607fd2 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 1.4E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_06095 563c27481b2c462b5ca5cb5a5d607fd2 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 1.4E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_13140 a2dd5f75e09cb21543524a11e112dd8e 483 PRINTS PR00045 Sigma-54 factor signature 399 410 2.4E-24 T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 LH59_13140 a2dd5f75e09cb21543524a11e112dd8e 483 PRINTS PR00045 Sigma-54 factor signature 457 475 2.4E-24 T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 LH59_13140 a2dd5f75e09cb21543524a11e112dd8e 483 PRINTS PR00045 Sigma-54 factor signature 193 210 2.4E-24 T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 LH59_13140 a2dd5f75e09cb21543524a11e112dd8e 483 PRINTS PR00045 Sigma-54 factor signature 383 395 2.4E-24 T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 LH59_13140 a2dd5f75e09cb21543524a11e112dd8e 483 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 6 50 1.2E-12 T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 LH59_13140 a2dd5f75e09cb21543524a11e112dd8e 483 Gene3D G3DSA:1.10.10.1330 122 253 1.1E-13 T 14-10-2018 IPR038709 RNA polymerase sigma-54 factor, core-binding domain superfamily LH59_13140 a2dd5f75e09cb21543524a11e112dd8e 483 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 10 481 1.2E-128 T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 LH59_13140 a2dd5f75e09cb21543524a11e112dd8e 483 Pfam PF04963 Sigma-54 factor, core binding domain 115 311 5.6E-46 T 14-10-2018 IPR007046 RNA polymerase sigma factor 54, core-binding domain GO:0003677|GO:0006352 LH59_13140 a2dd5f75e09cb21543524a11e112dd8e 483 PIRSF PIRSF000774 2 483 5.9E-137 T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 LH59_13140 a2dd5f75e09cb21543524a11e112dd8e 483 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 371 390 - T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 LH59_13140 a2dd5f75e09cb21543524a11e112dd8e 483 Pfam PF04552 Sigma-54, DNA binding domain 326 481 3.0E-60 T 14-10-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding LH59_13140 a2dd5f75e09cb21543524a11e112dd8e 483 Gene3D G3DSA:1.10.10.60 424 481 5.4E-19 T 14-10-2018 LH59_21315 fc2b0e3a18550eb707d9e1ea199ecc71 318 Pfam PF00248 Aldo/keto reductase family 15 311 5.1E-69 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain LH59_21315 fc2b0e3a18550eb707d9e1ea199ecc71 318 Gene3D G3DSA:3.20.20.100 1 317 3.6E-99 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily LH59_21315 fc2b0e3a18550eb707d9e1ea199ecc71 318 SUPERFAMILY SSF51430 1 312 4.32E-90 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily LH59_02260 8d15fa732d5156adf05e3f96d1e84916 389 SUPERFAMILY SSF53822 24 367 2.78E-78 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_02260 8d15fa732d5156adf05e3f96d1e84916 389 Pfam PF13458 Periplasmic binding protein 24 360 3.3E-67 T 14-10-2018 IPR028081 Leucine-binding protein domain LH59_02260 8d15fa732d5156adf05e3f96d1e84916 389 Gene3D G3DSA:3.40.50.2300 25 350 3.1E-89 T 14-10-2018 LH59_02260 8d15fa732d5156adf05e3f96d1e84916 389 Gene3D G3DSA:3.40.50.2300 141 360 3.1E-89 T 14-10-2018 LH59_08070 4f34b3aa3271e6c5c8e53824e7d6f582 253 Gene3D G3DSA:3.40.50.300 4 250 9.1E-53 T 14-10-2018 LH59_08070 4f34b3aa3271e6c5c8e53824e7d6f582 253 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 226 247 2.1E-5 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal LH59_08070 4f34b3aa3271e6c5c8e53824e7d6f582 253 Pfam PF00005 ABC transporter 23 178 2.2E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_08070 4f34b3aa3271e6c5c8e53824e7d6f582 253 SMART SM00382 31 225 3.4E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_08070 4f34b3aa3271e6c5c8e53824e7d6f582 253 SUPERFAMILY SSF52540 6 247 2.11E-54 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_14605 15090967d970620ae19d392ff94a0b5b 330 PIRSF PIRSF017082 1 328 6.4E-77 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_14605 15090967d970620ae19d392ff94a0b5b 330 Gene3D G3DSA:3.40.190.10 130 255 1.3E-102 T 14-10-2018 LH59_14605 15090967d970620ae19d392ff94a0b5b 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 319 3.6E-71 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_14605 15090967d970620ae19d392ff94a0b5b 330 Gene3D G3DSA:3.40.190.150 32 320 1.3E-102 T 14-10-2018 LH59_14605 15090967d970620ae19d392ff94a0b5b 330 SUPERFAMILY SSF53850 123 292 1.94E-14 T 14-10-2018 LH59_08850 3f890ef9844a821fe4bb2a35d89c7a61 156 PIRSF PIRSF004505 1 155 1.4E-43 T 14-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 LH59_08850 3f890ef9844a821fe4bb2a35d89c7a61 156 Gene3D G3DSA:3.40.1280.10 1 156 6.0E-48 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal LH59_08850 3f890ef9844a821fe4bb2a35d89c7a61 156 SUPERFAMILY SSF75217 2 154 1.88E-46 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases LH59_08850 3f890ef9844a821fe4bb2a35d89c7a61 156 Pfam PF02590 Predicted SPOUT methyltransferase 2 154 3.1E-47 T 14-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 LH59_08850 3f890ef9844a821fe4bb2a35d89c7a61 156 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 155 27.116 T 14-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 LH59_15430 f650d18693b658749a7c659621959c43 894 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 799 873 2.5E-10 T 14-10-2018 IPR019489 Clp ATPase, C-terminal LH59_15430 f650d18693b658749a7c659621959c43 894 Gene3D G3DSA:3.40.50.300 370 571 1.7E-48 T 14-10-2018 LH59_15430 f650d18693b658749a7c659621959c43 894 SMART SM01086 798 891 6.7E-11 T 14-10-2018 IPR019489 Clp ATPase, C-terminal LH59_15430 f650d18693b658749a7c659621959c43 894 SMART SM00382 624 768 7.3E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_15430 f650d18693b658749a7c659621959c43 894 SMART SM00382 224 369 2.4E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_15430 f650d18693b658749a7c659621959c43 894 TIGRFAM TIGR03345 VI_ClpV1: type VI secretion ATPase, ClpV1 family 12 882 0.0 T 14-10-2018 IPR017729 Type VI secretion system, ATPase ClpV1 LH59_15430 f650d18693b658749a7c659621959c43 894 SUPERFAMILY SSF52540 185 572 3.18E-74 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_15430 f650d18693b658749a7c659621959c43 894 SUPERFAMILY SSF81923 11 128 1.44E-17 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 LH59_15430 f650d18693b658749a7c659621959c43 894 Gene3D G3DSA:1.10.8.60 799 891 1.2E-10 T 14-10-2018 LH59_15430 f650d18693b658749a7c659621959c43 894 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 23 74 2.2E-4 T 14-10-2018 IPR004176 Clp, N-terminal LH59_15430 f650d18693b658749a7c659621959c43 894 Pfam PF07724 AAA domain (Cdc48 subfamily) 623 792 5.7E-43 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 LH59_15430 f650d18693b658749a7c659621959c43 894 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 320 332 - T 14-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 LH59_15430 f650d18693b658749a7c659621959c43 894 SUPERFAMILY SSF52540 573 870 6.93E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_15430 f650d18693b658749a7c659621959c43 894 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 702 720 2.6E-34 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 LH59_15430 f650d18693b658749a7c659621959c43 894 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 628 646 2.6E-34 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 LH59_15430 f650d18693b658749a7c659621959c43 894 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 673 691 2.6E-34 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 LH59_15430 f650d18693b658749a7c659621959c43 894 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 735 749 2.6E-34 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 LH59_15430 f650d18693b658749a7c659621959c43 894 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 229 341 5.4E-9 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 LH59_15430 f650d18693b658749a7c659621959c43 894 Gene3D G3DSA:3.40.50.300 178 368 1.2E-64 T 14-10-2018 LH59_15430 f650d18693b658749a7c659621959c43 894 Gene3D G3DSA:1.10.1780.10 1 160 8.6E-44 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 LH59_15430 f650d18693b658749a7c659621959c43 894 Gene3D G3DSA:3.40.50.300 577 797 3.0E-71 T 14-10-2018 LH59_19390 c4eea343480e214b70e6d0f40ff988ba 1121 SUPERFAMILY SSF51011 475 547 6.77E-19 T 14-10-2018 LH59_19390 c4eea343480e214b70e6d0f40ff988ba 1121 SUPERFAMILY SSF51445 12 465 4.96E-128 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily LH59_19390 c4eea343480e214b70e6d0f40ff988ba 1121 Gene3D G3DSA:3.90.1200.10 814 1117 5.0E-56 T 14-10-2018 LH59_19390 c4eea343480e214b70e6d0f40ff988ba 1121 TIGRFAM TIGR02456 treS_nterm: trehalose synthase 13 548 9.2E-282 T 14-10-2018 IPR012810 Trehalose synthase/alpha-amylase, N-terminal GO:0003824|GO:0005975 KEGG: 00500+5.4.99.16|MetaCyc: PWY-2622|MetaCyc: PWY-7900 LH59_19390 c4eea343480e214b70e6d0f40ff988ba 1121 SMART SM00642 21 420 1.2E-103 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 LH59_19390 c4eea343480e214b70e6d0f40ff988ba 1121 SUPERFAMILY SSF56112 755 1071 1.21E-15 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily LH59_19390 c4eea343480e214b70e6d0f40ff988ba 1121 Gene3D G3DSA:3.20.20.80 13 462 2.6E-218 T 14-10-2018 LH59_19390 c4eea343480e214b70e6d0f40ff988ba 1121 TIGRFAM TIGR02457 TreS_Cterm: putative maltokinase 564 1102 8.7E-159 T 14-10-2018 IPR012811 Trehalose synthase/probable maltokinase, C-terminal domain LH59_19390 c4eea343480e214b70e6d0f40ff988ba 1121 Pfam PF16657 Maltogenic Amylase, C-terminal domain 468 545 1.9E-30 T 14-10-2018 IPR032091 Maltogenic Amylase, C-terminal LH59_19390 c4eea343480e214b70e6d0f40ff988ba 1121 Pfam PF00128 Alpha amylase, catalytic domain 36 389 1.1E-71 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 LH59_19390 c4eea343480e214b70e6d0f40ff988ba 1121 Gene3D G3DSA:3.90.400.10 111 181 2.6E-218 T 14-10-2018 LH59_19390 c4eea343480e214b70e6d0f40ff988ba 1121 Gene3D G3DSA:2.60.40.1180 468 558 2.2E-32 T 14-10-2018 IPR013780 Glycosyl hydrolase, all-beta LH59_25545 983ef861e4f4b5fb38e969ea487498eb 338 SMART SM00062 34 263 2.2E-37 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_25545 983ef861e4f4b5fb38e969ea487498eb 338 Gene3D G3DSA:3.40.190.10 121 226 8.6E-45 T 14-10-2018 LH59_25545 983ef861e4f4b5fb38e969ea487498eb 338 SUPERFAMILY SSF53850 25 257 3.0E-42 T 14-10-2018 LH59_25545 983ef861e4f4b5fb38e969ea487498eb 338 Gene3D G3DSA:3.40.190.10 29 241 8.6E-45 T 14-10-2018 LH59_25545 983ef861e4f4b5fb38e969ea487498eb 338 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 57 70 - T 14-10-2018 IPR018313 Solute-binding protein family 3, conserved site LH59_25545 983ef861e4f4b5fb38e969ea487498eb 338 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 35 253 1.7E-26 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_22545 a021ee643b10f79b685ee1cd9fe54dbe 211 Gene3D G3DSA:3.40.30.10 7 203 1.7E-71 T 14-10-2018 LH59_22545 a021ee643b10f79b685ee1cd9fe54dbe 211 SUPERFAMILY SSF47616 90 203 1.13E-8 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily LH59_22545 a021ee643b10f79b685ee1cd9fe54dbe 211 Pfam PF13417 Glutathione S-transferase, N-terminal domain 14 85 8.4E-12 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 LH59_22545 a021ee643b10f79b685ee1cd9fe54dbe 211 Gene3D G3DSA:1.20.1050.10 89 195 1.7E-71 T 14-10-2018 LH59_22545 a021ee643b10f79b685ee1cd9fe54dbe 211 Pfam PF14834 Glutathione S-transferase, C-terminal domain 97 204 4.7E-34 T 14-10-2018 IPR034338 Glutathione S-transferases, subfamily 4, C-terminal KEGG: 00480+2.5.1.18|KEGG: 00980+2.5.1.18|KEGG: 00982+2.5.1.18|KEGG: 00983+2.5.1.18|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7533 LH59_22545 a021ee643b10f79b685ee1cd9fe54dbe 211 SUPERFAMILY SSF52833 11 92 4.94E-17 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_07500 c7200a53c537d8ca1655688b83766ca1 362 Gene3D G3DSA:3.10.20.30 255 362 1.9E-28 T 14-10-2018 IPR012675 Beta-grasp domain superfamily LH59_07500 c7200a53c537d8ca1655688b83766ca1 362 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 276 349 9.5E-16 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 LH59_07500 c7200a53c537d8ca1655688b83766ca1 362 SUPERFAMILY SSF63380 3 107 1.06E-27 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel LH59_07500 c7200a53c537d8ca1655688b83766ca1 362 TIGRFAM TIGR02160 PA_CoA_Oxy5: phenylacetate-CoA oxygenase/reductase, PaaK subunit 6 359 3.1E-142 T 14-10-2018 IPR011884 Phenylacetate-CoA oxygenase/reductase, PaaK subunit GO:0010124 LH59_07500 c7200a53c537d8ca1655688b83766ca1 362 Gene3D G3DSA:2.40.30.10 4 107 2.2E-25 T 14-10-2018 LH59_07500 c7200a53c537d8ca1655688b83766ca1 362 Pfam PF00970 Oxidoreductase FAD-binding domain 10 105 2.0E-12 T 14-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 LH59_07500 c7200a53c537d8ca1655688b83766ca1 362 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 118 137 4.3E-6 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 LH59_07500 c7200a53c537d8ca1655688b83766ca1 362 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 143 152 4.3E-6 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 LH59_07500 c7200a53c537d8ca1655688b83766ca1 362 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 155 166 4.3E-6 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 LH59_07500 c7200a53c537d8ca1655688b83766ca1 362 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 57 64 4.3E-6 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 LH59_07500 c7200a53c537d8ca1655688b83766ca1 362 SUPERFAMILY SSF54292 237 359 2.83E-28 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 LH59_07500 c7200a53c537d8ca1655688b83766ca1 362 SUPERFAMILY SSF52343 96 244 1.7E-32 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain LH59_07500 c7200a53c537d8ca1655688b83766ca1 362 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 307 315 - T 14-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 LH59_07500 c7200a53c537d8ca1655688b83766ca1 362 PRINTS PR00406 Cytochrome B5 reductase signature 155 166 2.7E-8 T 14-10-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 LH59_07500 c7200a53c537d8ca1655688b83766ca1 362 PRINTS PR00406 Cytochrome B5 reductase signature 214 222 2.7E-8 T 14-10-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 LH59_07500 c7200a53c537d8ca1655688b83766ca1 362 PRINTS PR00406 Cytochrome B5 reductase signature 93 107 2.7E-8 T 14-10-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 LH59_07500 c7200a53c537d8ca1655688b83766ca1 362 PRINTS PR00406 Cytochrome B5 reductase signature 118 137 2.7E-8 T 14-10-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 LH59_07500 c7200a53c537d8ca1655688b83766ca1 362 Gene3D G3DSA:3.40.50.80 111 249 4.1E-29 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain LH59_07500 c7200a53c537d8ca1655688b83766ca1 362 Pfam PF00175 Oxidoreductase NAD-binding domain 121 227 5.2E-17 T 14-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 LH59_26070 0fa688c1b49df2111ced879d554027cf 579 SUPERFAMILY SSF55124 1 125 1.8E-29 T 14-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 LH59_26070 0fa688c1b49df2111ced879d554027cf 579 Gene3D G3DSA:3.30.413.10 408 578 1.2E-28 T 14-10-2018 LH59_26070 0fa688c1b49df2111ced879d554027cf 579 Gene3D G3DSA:3.90.480.20 5 139 2.4E-23 T 14-10-2018 LH59_26070 0fa688c1b49df2111ced879d554027cf 579 Gene3D G3DSA:3.90.480.20 310 399 3.8E-19 T 14-10-2018 LH59_26070 0fa688c1b49df2111ced879d554027cf 579 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 411 562 2.0E-8 T 14-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 LH59_26070 0fa688c1b49df2111ced879d554027cf 579 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 327 398 9.4E-18 T 14-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 LH59_26070 0fa688c1b49df2111ced879d554027cf 579 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 53 109 1.2E-15 T 14-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 LH59_26070 0fa688c1b49df2111ced879d554027cf 579 SUPERFAMILY SSF55124 251 421 4.58E-26 T 14-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 LH59_26070 0fa688c1b49df2111ced879d554027cf 579 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 119 271 3.0E-40 T 14-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 LH59_26070 0fa688c1b49df2111ced879d554027cf 579 SUPERFAMILY SSF56014 120 281 8.51E-47 T 14-10-2018 LH59_26070 0fa688c1b49df2111ced879d554027cf 579 Gene3D G3DSA:3.30.413.10 147 275 8.5E-31 T 14-10-2018 LH59_26070 0fa688c1b49df2111ced879d554027cf 579 SUPERFAMILY SSF56014 408 563 1.83E-35 T 14-10-2018 LH59_11630 d702e2e224b857260a918eebf037dfcd 237 Pfam PF01914 MarC family integral membrane protein 13 220 2.8E-35 T 14-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 LH59_11630 d702e2e224b857260a918eebf037dfcd 237 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 14 216 5.3E-33 T 14-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 LH59_22455 cdc99c86ca7ea70447576c649e8a1d1b 280 Gene3D G3DSA:3.40.50.300 1 249 8.0E-62 T 14-10-2018 LH59_22455 cdc99c86ca7ea70447576c649e8a1d1b 280 SUPERFAMILY SSF52540 3 241 2.06E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_22455 cdc99c86ca7ea70447576c649e8a1d1b 280 Pfam PF00005 ABC transporter 21 181 1.9E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_22455 cdc99c86ca7ea70447576c649e8a1d1b 280 SMART SM00382 30 259 1.3E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_22455 cdc99c86ca7ea70447576c649e8a1d1b 280 TIGRFAM TIGR02315 ABC_phnC: phosphonate ABC transporter, ATP-binding protein 5 250 1.8E-84 T 14-10-2018 IPR012693 ABC transporter, phosphonate import, PhnC GO:0005524|GO:0015416|GO:0015716|GO:0016020 LH59_22455 cdc99c86ca7ea70447576c649e8a1d1b 280 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_24380 63c590d02818b7f2f787b76bebc07002 272 SMART SM00934 17 257 5.0E-52 T 14-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 LH59_24380 63c590d02818b7f2f787b76bebc07002 272 Hamap MF_01215 Orotidine 5'-phosphate decarboxylase [pyrF]. 2 270 33.546 T 14-10-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 LH59_24380 63c590d02818b7f2f787b76bebc07002 272 SUPERFAMILY SSF51366 2 267 1.74E-73 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 LH59_24380 63c590d02818b7f2f787b76bebc07002 272 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 90 103 - T 14-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 LH59_24380 63c590d02818b7f2f787b76bebc07002 272 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 17 248 2.6E-29 T 14-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 LH59_24380 63c590d02818b7f2f787b76bebc07002 272 Gene3D G3DSA:3.20.20.70 1 271 2.2E-95 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_24380 63c590d02818b7f2f787b76bebc07002 272 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 3 253 7.0E-69 T 14-10-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 LH59_15480 59ae682a78691e8362f88c6f1012c8b9 259 Gene3D G3DSA:1.25.40.590 26 188 9.5E-42 T 14-10-2018 IPR038522 Type IV / VI secretion system, DotU superfamily LH59_15480 59ae682a78691e8362f88c6f1012c8b9 259 TIGRFAM TIGR03349 IV_VI_DotU: type IV/VI secretion system protein, DotU family 29 233 4.2E-60 T 14-10-2018 IPR017732 Type IV / VI secretion system, DotU LH59_15480 59ae682a78691e8362f88c6f1012c8b9 259 Pfam PF09850 Type VI secretion system protein DotU 30 227 5.0E-59 T 14-10-2018 IPR017732 Type IV / VI secretion system, DotU LH59_26340 698c59ce3580d4546502da4f5121781d 470 Gene3D G3DSA:3.30.43.10 1 95 5.2E-26 T 14-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 LH59_26340 698c59ce3580d4546502da4f5121781d 470 Gene3D G3DSA:3.30.70.2740 343 429 2.7E-27 T 14-10-2018 LH59_26340 698c59ce3580d4546502da4f5121781d 470 Gene3D G3DSA:3.30.465.10 97 218 6.1E-43 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 LH59_26340 698c59ce3580d4546502da4f5121781d 470 SUPERFAMILY SSF55103 222 470 4.09E-55 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 LH59_26340 698c59ce3580d4546502da4f5121781d 470 SUPERFAMILY SSF56176 5 217 5.18E-72 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 LH59_26340 698c59ce3580d4546502da4f5121781d 470 Pfam PF02913 FAD linked oxidases, C-terminal domain 221 469 1.2E-51 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 LH59_26340 698c59ce3580d4546502da4f5121781d 470 Pfam PF01565 FAD binding domain 42 179 1.3E-35 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 LH59_26340 698c59ce3580d4546502da4f5121781d 470 Gene3D G3DSA:1.10.45.10 430 470 4.6E-17 T 14-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 LH59_26340 698c59ce3580d4546502da4f5121781d 470 Gene3D G3DSA:3.30.70.2190 220 342 4.2E-33 T 14-10-2018 LH59_27285 67901b61ea33b1a888ed07ff0ca9a44c 422 Gene3D G3DSA:3.40.50.2000 218 404 3.8E-57 T 14-10-2018 LH59_27285 67901b61ea33b1a888ed07ff0ca9a44c 422 Pfam PF00534 Glycosyl transferases group 1 301 402 9.0E-8 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 LH59_27285 67901b61ea33b1a888ed07ff0ca9a44c 422 Gene3D G3DSA:3.40.50.11720 34 212 3.9E-40 T 14-10-2018 IPR038107 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal domain superfamily KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 LH59_27285 67901b61ea33b1a888ed07ff0ca9a44c 422 SUPERFAMILY SSF53756 59 412 3.4E-17 T 14-10-2018 LH59_27285 67901b61ea33b1a888ed07ff0ca9a44c 422 Pfam PF04413 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) 37 213 2.6E-50 T 14-10-2018 IPR007507 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 LH59_21950 ac190b82f89a5db9b7e337124be9ce34 436 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 355 375 - T 14-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 LH59_21950 ac190b82f89a5db9b7e337124be9ce34 436 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 28 430 2.8E-104 T 14-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 LH59_21950 ac190b82f89a5db9b7e337124be9ce34 436 Pfam PF00860 Permease family 32 408 8.7E-89 T 14-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 LH59_05075 7c1601bbdc3081903bcdbea45c41355d 368 Pfam PF13609 Gram-negative porin 19 343 1.4E-46 T 14-10-2018 LH59_05075 7c1601bbdc3081903bcdbea45c41355d 368 Gene3D G3DSA:2.40.160.10 19 368 1.7E-68 T 14-10-2018 IPR023614 Porin domain superfamily LH59_05075 7c1601bbdc3081903bcdbea45c41355d 368 PRINTS PR00184 Neisseria sp. porin signature 59 84 1.8E-5 T 14-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 LH59_05075 7c1601bbdc3081903bcdbea45c41355d 368 PRINTS PR00184 Neisseria sp. porin signature 317 341 1.8E-5 T 14-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 LH59_05075 7c1601bbdc3081903bcdbea45c41355d 368 PRINTS PR00184 Neisseria sp. porin signature 157 174 1.8E-5 T 14-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 LH59_05075 7c1601bbdc3081903bcdbea45c41355d 368 SUPERFAMILY SSF56935 28 368 1.43E-58 T 14-10-2018 LH59_26535 f30e3117571f1020132166ec229cc0f0 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 318 6.6E-80 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_26535 f30e3117571f1020132166ec229cc0f0 322 Gene3D G3DSA:3.40.190.150 27 312 2.6E-106 T 14-10-2018 LH59_26535 f30e3117571f1020132166ec229cc0f0 322 SUPERFAMILY SSF53850 113 281 1.17E-15 T 14-10-2018 LH59_26535 f30e3117571f1020132166ec229cc0f0 322 PIRSF PIRSF017082 1 321 7.1E-84 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_26535 f30e3117571f1020132166ec229cc0f0 322 Gene3D G3DSA:3.40.190.10 124 247 2.6E-106 T 14-10-2018 LH59_17130 dc6c7e4b8e81cc6c7872182c46795535 393 Pfam PF13458 Periplasmic binding protein 37 358 1.9E-62 T 14-10-2018 IPR028081 Leucine-binding protein domain LH59_17130 dc6c7e4b8e81cc6c7872182c46795535 393 Gene3D G3DSA:3.40.50.2300 43 352 7.9E-76 T 14-10-2018 LH59_17130 dc6c7e4b8e81cc6c7872182c46795535 393 Gene3D G3DSA:3.40.50.2300 153 290 7.9E-76 T 14-10-2018 LH59_17130 dc6c7e4b8e81cc6c7872182c46795535 393 SUPERFAMILY SSF53822 36 386 1.24E-62 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_14205 10991025fc6a75e04163a874ceab31cf 150 Gene3D G3DSA:1.10.10.10 2 144 7.6E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_14205 10991025fc6a75e04163a874ceab31cf 150 ProSitePatterns PS01117 MarR-type HTH domain signature. 80 114 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site LH59_14205 10991025fc6a75e04163a874ceab31cf 150 Pfam PF12802 MarR family 39 105 3.9E-11 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_14205 10991025fc6a75e04163a874ceab31cf 150 SMART SM00347 34 140 1.4E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_14205 10991025fc6a75e04163a874ceab31cf 150 SUPERFAMILY SSF46785 11 143 1.01E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_19060 f45aef588d0fe631435e0ab6a1a4e3fc 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 3.3E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_19060 f45aef588d0fe631435e0ab6a1a4e3fc 301 SUPERFAMILY SSF53850 89 292 2.53E-40 T 14-10-2018 LH59_19060 f45aef588d0fe631435e0ab6a1a4e3fc 301 SUPERFAMILY SSF46785 2 84 6.57E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_19060 f45aef588d0fe631435e0ab6a1a4e3fc 301 Gene3D G3DSA:1.10.10.10 2 88 6.7E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_19060 f45aef588d0fe631435e0ab6a1a4e3fc 301 Gene3D G3DSA:3.40.190.290 91 293 7.3E-58 T 14-10-2018 LH59_19060 f45aef588d0fe631435e0ab6a1a4e3fc 301 Pfam PF03466 LysR substrate binding domain 88 292 2.1E-41 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_02045 493844e6761b9fe4abb4d13699533538 701 Gene3D G3DSA:1.10.8.630 20 125 6.5E-28 T 14-10-2018 LH59_02045 493844e6761b9fe4abb4d13699533538 701 Gene3D G3DSA:3.40.50.300 145 340 6.4E-72 T 14-10-2018 LH59_02045 493844e6761b9fe4abb4d13699533538 701 SMART SM00487 153 357 7.3E-13 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain LH59_02045 493844e6761b9fe4abb4d13699533538 701 SMART SM00490 457 554 5.7E-7 T 14-10-2018 IPR001650 Helicase, C-terminal LH59_02045 493844e6761b9fe4abb4d13699533538 701 TIGRFAM TIGR00595 priA: primosomal protein N' 178 699 8.7E-171 T 14-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 LH59_02045 493844e6761b9fe4abb4d13699533538 701 Pfam PF00270 DEAD/DEAH box helicase 159 324 1.6E-11 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 LH59_02045 493844e6761b9fe4abb4d13699533538 701 SUPERFAMILY SSF52540 175 565 1.16E-37 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_02045 493844e6761b9fe4abb4d13699533538 701 Hamap MF_00983 Probable primosomal protein N' [priA]. 23 701 23.623 T 14-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 LH59_02045 493844e6761b9fe4abb4d13699533538 701 Pfam PF00271 Helicase conserved C-terminal domain 459 553 1.9E-5 T 14-10-2018 IPR001650 Helicase, C-terminal LH59_22405 de107f5dddd02a484343647eebc200ff 240 Gene3D G3DSA:3.40.1410.10 72 227 2.2E-28 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily LH59_22405 de107f5dddd02a484343647eebc200ff 240 SUPERFAMILY SSF64288 61 236 8.95E-34 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily LH59_22405 de107f5dddd02a484343647eebc200ff 240 SMART SM00866 94 233 8.0E-23 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LH59_22405 de107f5dddd02a484343647eebc200ff 240 TIGRFAM TIGR02325 C_P_lyase_phnF: phosphonate metabolism transcriptional regulator PhnF 3 236 2.4E-72 T 14-10-2018 IPR012702 Phosphonate C-P lyase system, transcriptional regulator PhnF LH59_22405 de107f5dddd02a484343647eebc200ff 240 SMART SM00345 14 73 1.3E-21 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_22405 de107f5dddd02a484343647eebc200ff 240 Gene3D G3DSA:1.10.10.10 2 71 7.5E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_22405 de107f5dddd02a484343647eebc200ff 240 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 73 3.4E-20 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_22405 de107f5dddd02a484343647eebc200ff 240 SUPERFAMILY SSF46785 1 82 2.29E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_22405 de107f5dddd02a484343647eebc200ff 240 Pfam PF07702 UTRA domain 102 231 4.8E-25 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LH59_22405 de107f5dddd02a484343647eebc200ff 240 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 4.2E-9 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_22405 de107f5dddd02a484343647eebc200ff 240 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 4.2E-9 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_09530 eb651135f30214f493fa163ef6a199df 298 SUPERFAMILY SSF103481 202 295 1.44E-11 T 14-10-2018 LH59_09530 eb651135f30214f493fa163ef6a199df 298 Pfam PF00892 EamA-like transporter family 20 152 6.1E-16 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_09530 eb651135f30214f493fa163ef6a199df 298 Pfam PF00892 EamA-like transporter family 161 291 6.1E-10 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_09530 eb651135f30214f493fa163ef6a199df 298 SUPERFAMILY SSF103481 57 156 2.48E-14 T 14-10-2018 LH59_08610 626522e9c72717d67bf92bfc7b9c844d 324 SUPERFAMILY SSF53850 26 289 2.59E-6 T 14-10-2018 LH59_08610 626522e9c72717d67bf92bfc7b9c844d 324 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 31 285 6.3E-69 T 14-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 LH59_08610 626522e9c72717d67bf92bfc7b9c844d 324 PIRSF PIRSF006470 1 324 4.6E-96 T 14-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 LH59_08610 626522e9c72717d67bf92bfc7b9c844d 324 Gene3D G3DSA:3.40.190.170 23 324 3.4E-108 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily LH59_08610 626522e9c72717d67bf92bfc7b9c844d 324 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 31 310 2.3E-86 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 LH59_21320 46da112b748468bea7bb6449d0358bfa 324 PIRSF PIRSF017082 1 323 1.2E-84 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_21320 46da112b748468bea7bb6449d0358bfa 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 320 4.0E-81 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_21320 46da112b748468bea7bb6449d0358bfa 324 Gene3D G3DSA:3.40.190.10 125 249 2.1E-113 T 14-10-2018 LH59_21320 46da112b748468bea7bb6449d0358bfa 324 SUPERFAMILY SSF53850 94 286 6.21E-14 T 14-10-2018 LH59_21320 46da112b748468bea7bb6449d0358bfa 324 Gene3D G3DSA:3.40.190.150 28 314 2.1E-113 T 14-10-2018 LH59_06715 df00f63a2e661eb390d58ad87ab4b60d 548 SUPERFAMILY SSF54373 212 306 8.24E-38 T 14-10-2018 LH59_06715 df00f63a2e661eb390d58ad87ab4b60d 548 Gene3D G3DSA:3.30.70.20 449 543 5.0E-38 T 14-10-2018 LH59_06715 df00f63a2e661eb390d58ad87ab4b60d 548 Pfam PF13450 NAD(P)-binding Rossmann-like domain 13 58 5.7E-6 T 14-10-2018 LH59_06715 df00f63a2e661eb390d58ad87ab4b60d 548 Pfam PF05187 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S 444 546 4.2E-49 T 14-10-2018 LH59_06715 df00f63a2e661eb390d58ad87ab4b60d 548 Gene3D G3DSA:3.30.9.90 80 448 2.7E-197 T 14-10-2018 LH59_06715 df00f63a2e661eb390d58ad87ab4b60d 548 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 10 32 5.0E-7 T 14-10-2018 LH59_06715 df00f63a2e661eb390d58ad87ab4b60d 548 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 179 194 5.0E-7 T 14-10-2018 LH59_06715 df00f63a2e661eb390d58ad87ab4b60d 548 Gene3D G3DSA:3.50.50.60 8 385 2.7E-197 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_06715 df00f63a2e661eb390d58ad87ab4b60d 548 SUPERFAMILY SSF51905 3 446 5.56E-55 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_06715 df00f63a2e661eb390d58ad87ab4b60d 548 SUPERFAMILY SSF54862 448 546 1.44E-27 T 14-10-2018 LH59_19950 7dd4b976828dbb6d66caae2668b16f73 378 Pfam PF02563 Polysaccharide biosynthesis/export protein 79 176 1.1E-25 T 14-10-2018 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 LH59_19950 7dd4b976828dbb6d66caae2668b16f73 378 Pfam PF10531 SLBB domain 268 313 2.8E-6 T 14-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_19950 7dd4b976828dbb6d66caae2668b16f73 378 Pfam PF10531 SLBB domain 183 234 2.1E-10 T 14-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_19950 7dd4b976828dbb6d66caae2668b16f73 378 Gene3D G3DSA:3.30.1950.10 86 180 2.0E-103 T 14-10-2018 LH59_19950 7dd4b976828dbb6d66caae2668b16f73 378 Gene3D G3DSA:3.10.560.10 51 349 2.0E-103 T 14-10-2018 LH59_19950 7dd4b976828dbb6d66caae2668b16f73 378 Gene3D G3DSA:3.10.560.10 63 265 2.0E-103 T 14-10-2018 LH59_19575 e46b15c35ccd9a86f888664456d2b295 243 SUPERFAMILY SSF52540 5 229 2.6E-75 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_19575 e46b15c35ccd9a86f888664456d2b295 243 PIRSF PIRSF039085 1 243 6.7E-107 T 14-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 LH59_19575 e46b15c35ccd9a86f888664456d2b295 243 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_19575 e46b15c35ccd9a86f888664456d2b295 243 Pfam PF00005 ABC transporter 20 169 4.2E-35 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_19575 e46b15c35ccd9a86f888664456d2b295 243 Gene3D G3DSA:3.40.50.300 1 241 3.0E-74 T 14-10-2018 LH59_19575 e46b15c35ccd9a86f888664456d2b295 243 SMART SM00382 29 217 7.3E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_09560 797f9b976cf519188594944327c904ef 524 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 74 436 4.1E-92 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain LH59_09560 797f9b976cf519188594944327c904ef 524 SUPERFAMILY SSF53850 29 523 5.43E-132 T 14-10-2018 LH59_09560 797f9b976cf519188594944327c904ef 524 Gene3D G3DSA:3.40.190.10 17 281 1.8E-75 T 14-10-2018 LH59_09560 797f9b976cf519188594944327c904ef 524 PIRSF PIRSF002741 2 524 2.3E-149 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 LH59_09560 797f9b976cf519188594944327c904ef 524 Gene3D G3DSA:3.10.105.10 282 493 7.8E-48 T 14-10-2018 LH59_02830 326f557df390b79a8ada528f88bf2810 221 Gene3D G3DSA:1.10.357.10 1 201 1.6E-18 T 14-10-2018 LH59_02830 326f557df390b79a8ada528f88bf2810 221 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 56 5.3E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_02830 326f557df390b79a8ada528f88bf2810 221 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 6.7E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_02830 326f557df390b79a8ada528f88bf2810 221 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 6.7E-5 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_02830 326f557df390b79a8ada528f88bf2810 221 SUPERFAMILY SSF46689 2 60 4.44E-13 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_03000 1d1c30137f13540271ed17e189cb2a34 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 1.2E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_03000 1d1c30137f13540271ed17e189cb2a34 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.2E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_03000 1d1c30137f13540271ed17e189cb2a34 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 1.2E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_03000 1d1c30137f13540271ed17e189cb2a34 268 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LH59_03000 1d1c30137f13540271ed17e189cb2a34 268 SUPERFAMILY SSF51735 11 251 5.79E-72 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_03000 1d1c30137f13540271ed17e189cb2a34 268 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 249 1.2E-56 T 14-10-2018 LH59_03000 1d1c30137f13540271ed17e189cb2a34 268 Gene3D G3DSA:3.40.50.720 7 255 2.7E-73 T 14-10-2018 LH59_03000 1d1c30137f13540271ed17e189cb2a34 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 2.5E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_03000 1d1c30137f13540271ed17e189cb2a34 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 2.5E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_03000 1d1c30137f13540271ed17e189cb2a34 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 2.5E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_03000 1d1c30137f13540271ed17e189cb2a34 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 2.5E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_03000 1d1c30137f13540271ed17e189cb2a34 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 2.5E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_03000 1d1c30137f13540271ed17e189cb2a34 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 2.5E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_22350 1307c4a1e8bc85ae0ded61431fd24b46 354 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 329 4.7E-102 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 LH59_22350 1307c4a1e8bc85ae0ded61431fd24b46 354 Gene3D G3DSA:3.20.20.70 1 354 4.7E-149 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_22350 1307c4a1e8bc85ae0ded61431fd24b46 354 TIGRFAM TIGR01521 FruBisAldo_II_B: fructose-bisphosphate aldolase, class II, Calvin cycle subtype 3 349 1.3E-188 T 14-10-2018 IPR006412 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 LH59_22350 1307c4a1e8bc85ae0ded61431fd24b46 354 PIRSF PIRSF001359 1 329 2.0E-86 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 LH59_22350 1307c4a1e8bc85ae0ded61431fd24b46 354 SUPERFAMILY SSF51569 1 328 1.42E-106 T 14-10-2018 LH59_22350 1307c4a1e8bc85ae0ded61431fd24b46 354 Pfam PF01116 Fructose-bisphosphate aldolase class-II 4 327 7.1E-96 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 LH59_22350 1307c4a1e8bc85ae0ded61431fd24b46 354 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 139 150 - T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 LH59_22350 1307c4a1e8bc85ae0ded61431fd24b46 354 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 73 85 - T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 LH59_15290 03a2395c605b43ddfcbe184c22e29b77 222 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 9 189 1.0E-17 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 LH59_15290 03a2395c605b43ddfcbe184c22e29b77 222 SUPERFAMILY SSF56784 6 222 2.71E-50 T 14-10-2018 IPR036412 HAD-like superfamily LH59_15290 03a2395c605b43ddfcbe184c22e29b77 222 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 188 4.1E-25 T 14-10-2018 LH59_15290 03a2395c605b43ddfcbe184c22e29b77 222 Gene3D G3DSA:3.40.50.1000 9 210 2.8E-61 T 14-10-2018 IPR023214 HAD superfamily LH59_15290 03a2395c605b43ddfcbe184c22e29b77 222 Gene3D G3DSA:1.10.150.240 21 87 2.8E-61 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 LH59_20520 9111eab0c5914372b6592e74fa525d60 264 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 259 5.5E-45 T 14-10-2018 LH59_20520 9111eab0c5914372b6592e74fa525d60 264 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LH59_20520 9111eab0c5914372b6592e74fa525d60 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 2.8E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_20520 9111eab0c5914372b6592e74fa525d60 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 2.8E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_20520 9111eab0c5914372b6592e74fa525d60 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 2.8E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_20520 9111eab0c5914372b6592e74fa525d60 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 7.3E-28 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_20520 9111eab0c5914372b6592e74fa525d60 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 7.3E-28 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_20520 9111eab0c5914372b6592e74fa525d60 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 7.3E-28 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_20520 9111eab0c5914372b6592e74fa525d60 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 7.3E-28 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_20520 9111eab0c5914372b6592e74fa525d60 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 7.3E-28 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_20520 9111eab0c5914372b6592e74fa525d60 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 7.3E-28 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_20520 9111eab0c5914372b6592e74fa525d60 264 Gene3D G3DSA:3.40.50.720 1 263 1.8E-77 T 14-10-2018 LH59_20520 9111eab0c5914372b6592e74fa525d60 264 SUPERFAMILY SSF51735 6 260 3.66E-70 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_19300 a0fdc2388f6a78903ae80efb7ba80ecc 182 Pfam PF13628 Domain of unknown function (DUF4142) 41 176 5.4E-43 T 14-10-2018 IPR025419 Domain of unknown function DUF4142 LH59_19300 a0fdc2388f6a78903ae80efb7ba80ecc 182 Gene3D G3DSA:1.20.1260.10 28 179 1.2E-5 T 14-10-2018 IPR012347 Ferritin-like LH59_06225 1bcb95779f2db0800c4f79b2dc3764c5 244 SMART SM00448 10 121 9.0E-47 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_06225 1bcb95779f2db0800c4f79b2dc3764c5 244 Gene3D G3DSA:3.40.50.2300 2 131 2.3E-40 T 14-10-2018 LH59_06225 1bcb95779f2db0800c4f79b2dc3764c5 244 Pfam PF00072 Response regulator receiver domain 12 122 1.9E-32 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_06225 1bcb95779f2db0800c4f79b2dc3764c5 244 SUPERFAMILY SSF46894 138 240 6.8E-28 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LH59_06225 1bcb95779f2db0800c4f79b2dc3764c5 244 Gene3D G3DSA:1.10.10.10 136 243 2.5E-35 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_06225 1bcb95779f2db0800c4f79b2dc3764c5 244 SUPERFAMILY SSF52172 6 131 1.24E-43 T 14-10-2018 IPR011006 CheY-like superfamily LH59_06225 1bcb95779f2db0800c4f79b2dc3764c5 244 Pfam PF00486 Transcriptional regulatory protein, C terminal 162 238 2.7E-21 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_06225 1bcb95779f2db0800c4f79b2dc3764c5 244 SMART SM00862 162 238 1.7E-22 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_07385 b0233e6c75f2af0eaceb28231dcf7208 608 Gene3D G3DSA:1.10.540.10 26 158 4.4E-13 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 LH59_07385 b0233e6c75f2af0eaceb28231dcf7208 608 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 487 595 1.1E-22 T 14-10-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain LH59_07385 b0233e6c75f2af0eaceb28231dcf7208 608 Gene3D G3DSA:2.40.110.10 159 293 1.8E-25 T 14-10-2018 LH59_07385 b0233e6c75f2af0eaceb28231dcf7208 608 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 3 33 9.6E-9 T 14-10-2018 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria LH59_07385 b0233e6c75f2af0eaceb28231dcf7208 608 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 39 155 6.8E-12 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 LH59_07385 b0233e6c75f2af0eaceb28231dcf7208 608 SUPERFAMILY SSF47203 286 461 3.87E-45 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 LH59_07385 b0233e6c75f2af0eaceb28231dcf7208 608 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 161 266 1.9E-16 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 LH59_07385 b0233e6c75f2af0eaceb28231dcf7208 608 SUPERFAMILY SSF56645 37 267 4.58E-54 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 LH59_07385 b0233e6c75f2af0eaceb28231dcf7208 608 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 288 455 1.1E-27 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LH59_07385 b0233e6c75f2af0eaceb28231dcf7208 608 Gene3D G3DSA:1.20.140.10 294 458 4.5E-49 T 14-10-2018 LH59_07290 3a136087cfea249101948a4972968504 229 Gene3D G3DSA:3.40.50.300 8 227 3.9E-77 T 14-10-2018 LH59_07290 3a136087cfea249101948a4972968504 229 SUPERFAMILY SSF52540 13 224 3.96E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_07290 3a136087cfea249101948a4972968504 229 TIGRFAM TIGR00017 cmk: cytidylate kinase 13 221 5.0E-72 T 14-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 LH59_07290 3a136087cfea249101948a4972968504 229 Hamap MF_00238 Cytidylate kinase [cmk]. 13 227 32.398 T 14-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 LH59_07290 3a136087cfea249101948a4972968504 229 Pfam PF02224 Cytidylate kinase 15 221 8.6E-72 T 14-10-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 LH59_21100 9f7b5865a9a419ca734be55265e49c1c 241 TIGRFAM TIGR00781 ccoO: cytochrome c oxidase, cbb3-type, subunit II 11 186 1.1E-80 T 14-10-2018 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO LH59_21100 9f7b5865a9a419ca734be55265e49c1c 241 SUPERFAMILY SSF46626 21 202 6.36E-28 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_21100 9f7b5865a9a419ca734be55265e49c1c 241 Gene3D G3DSA:1.10.760.10 48 210 1.4E-69 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_21100 9f7b5865a9a419ca734be55265e49c1c 241 Pfam PF02433 Cytochrome C oxidase, mono-heme subunit/FixO 11 190 6.3E-77 T 14-10-2018 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO LH59_27595 6922b1436b723057a2cd38031f8443e5 519 SMART SM00869 243 509 1.9E-45 T 14-10-2018 IPR005546 Autotransporter beta-domain LH59_27595 6922b1436b723057a2cd38031f8443e5 519 SUPERFAMILY SSF103515 239 519 3.92E-59 T 14-10-2018 IPR036709 Autotransporter beta-domain superfamily LH59_27595 6922b1436b723057a2cd38031f8443e5 519 Gene3D G3DSA:2.40.128.130 177 519 8.7E-71 T 14-10-2018 IPR036709 Autotransporter beta-domain superfamily LH59_27595 6922b1436b723057a2cd38031f8443e5 519 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 33 519 8.9E-41 T 14-10-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 LH59_27595 6922b1436b723057a2cd38031f8443e5 519 Pfam PF03797 Autotransporter beta-domain 246 499 4.6E-59 T 14-10-2018 IPR005546 Autotransporter beta-domain LH59_26475 854242013a4201d62eb1002296cd6ac5 200 Gene3D G3DSA:3.40.50.450 1 197 3.2E-76 T 14-10-2018 LH59_26475 854242013a4201d62eb1002296cd6ac5 200 Pfam PF03641 Possible lysine decarboxylase 48 176 6.6E-43 T 14-10-2018 IPR031100 LOG family LH59_26475 854242013a4201d62eb1002296cd6ac5 200 SUPERFAMILY SSF102405 3 176 8.85E-61 T 14-10-2018 LH59_26475 854242013a4201d62eb1002296cd6ac5 200 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 4 179 2.1E-59 T 14-10-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG LH59_18870 9f9fdb20a9b6ef9815fc7367b3d7a5a8 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 107 276 2.7E-20 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_18870 9f9fdb20a9b6ef9815fc7367b3d7a5a8 280 SUPERFAMILY SSF161098 84 269 3.14E-23 T 14-10-2018 IPR035906 MetI-like superfamily LH59_18870 9f9fdb20a9b6ef9815fc7367b3d7a5a8 280 Gene3D G3DSA:1.10.3720.10 87 276 4.1E-18 T 14-10-2018 IPR035906 MetI-like superfamily LH59_18870 9f9fdb20a9b6ef9815fc7367b3d7a5a8 280 TIGRFAM TIGR01183 ntrB: nitrate ABC transporter, permease protein 73 270 1.5E-71 T 14-10-2018 IPR005889 Nitrate transport permease GO:0015112|GO:0015706|GO:0016021 LH59_17305 7880aaefe983d6062ebf29a68d38cb3b 396 Gene3D G3DSA:1.20.1250.20 14 387 1.9E-18 T 14-10-2018 LH59_17305 7880aaefe983d6062ebf29a68d38cb3b 396 SUPERFAMILY SSF103473 14 391 2.22E-24 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_25470 1c1d0d289e27052cb1ac347370158bd3 338 Gene3D G3DSA:3.30.420.310 98 325 2.9E-67 T 14-10-2018 LH59_25470 1c1d0d289e27052cb1ac347370158bd3 338 Pfam PF05035 2-keto-3-deoxy-galactonokinase 15 320 4.4E-100 T 14-10-2018 IPR007729 2-keto-3-deoxy-galactonokinase GO:0008671|GO:0034194 KEGG: 00052+2.7.1.58|MetaCyc: PWY-7130 LH59_25470 1c1d0d289e27052cb1ac347370158bd3 338 Gene3D G3DSA:3.30.420.300 5 97 1.4E-24 T 14-10-2018 LH59_12910 66685da50d0804b45282d5f9ab3315e8 283 Gene3D G3DSA:1.10.3720.10 1 276 9.1E-56 T 14-10-2018 IPR035906 MetI-like superfamily LH59_12910 66685da50d0804b45282d5f9ab3315e8 283 SUPERFAMILY SSF161098 4 279 1.96E-59 T 14-10-2018 IPR035906 MetI-like superfamily LH59_12910 66685da50d0804b45282d5f9ab3315e8 283 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 278 1.1E-20 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_06230 4f0325a16b7efe1f4bc5878727cff2be 418 Gene3D G3DSA:3.30.420.40 100 207 4.8E-63 T 14-10-2018 LH59_06230 4f0325a16b7efe1f4bc5878727cff2be 418 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 5 238 1.5E-57 T 14-10-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 LH59_06230 4f0325a16b7efe1f4bc5878727cff2be 418 Pfam PF00814 Glycoprotease family 37 135 3.8E-25 T 14-10-2018 IPR000905 Gcp-like domain LH59_06230 4f0325a16b7efe1f4bc5878727cff2be 418 Pfam PF00583 Acetyltransferase (GNAT) family 290 383 4.0E-15 T 14-10-2018 IPR000182 GNAT domain LH59_06230 4f0325a16b7efe1f4bc5878727cff2be 418 SUPERFAMILY SSF53067 114 236 8.42E-15 T 14-10-2018 LH59_06230 4f0325a16b7efe1f4bc5878727cff2be 418 Gene3D G3DSA:3.30.420.40 5 241 4.8E-63 T 14-10-2018 LH59_06230 4f0325a16b7efe1f4bc5878727cff2be 418 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 274 406 3.9E-29 T 14-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 LH59_06230 4f0325a16b7efe1f4bc5878727cff2be 418 SUPERFAMILY SSF55729 269 411 3.66E-32 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_06230 4f0325a16b7efe1f4bc5878727cff2be 418 Gene3D G3DSA:3.40.630.30 268 416 4.6E-41 T 14-10-2018 LH59_06230 4f0325a16b7efe1f4bc5878727cff2be 418 SUPERFAMILY SSF53067 5 107 3.63E-22 T 14-10-2018 LH59_09160 f8a6d56105c824583e215523a17a9ac2 166 Gene3D G3DSA:1.10.260.40 19 102 9.5E-22 T 14-10-2018 LH59_09160 f8a6d56105c824583e215523a17a9ac2 166 Pfam PF13413 Helix-turn-helix domain 26 85 1.1E-19 T 14-10-2018 LH59_09160 f8a6d56105c824583e215523a17a9ac2 166 SUPERFAMILY SSF47413 22 64 1.94E-5 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 LH59_19650 b2ab33a961de8439bf6a399bd6e62c2f 234 Gene3D G3DSA:3.40.50.300 1 234 3.8E-67 T 14-10-2018 LH59_19650 b2ab33a961de8439bf6a399bd6e62c2f 234 SUPERFAMILY SSF52540 2 232 6.3E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_19650 b2ab33a961de8439bf6a399bd6e62c2f 234 SMART SM00382 26 213 7.1E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_19650 b2ab33a961de8439bf6a399bd6e62c2f 234 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_19650 b2ab33a961de8439bf6a399bd6e62c2f 234 Pfam PF00005 ABC transporter 17 162 5.7E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_15095 6327417f34fda273fd467a149d58c7fb 386 Gene3D G3DSA:3.40.50.2300 16 346 9.8E-134 T 14-10-2018 LH59_15095 6327417f34fda273fd467a149d58c7fb 386 SUPERFAMILY SSF53822 15 379 7.07E-90 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_15095 6327417f34fda273fd467a149d58c7fb 386 Pfam PF13433 Periplasmic binding protein domain 14 376 2.0E-131 T 14-10-2018 LH59_15095 6327417f34fda273fd467a149d58c7fb 386 Gene3D G3DSA:3.40.50.2300 129 365 9.8E-134 T 14-10-2018 LH59_13625 79d2a4cfbcd0e53c63fda06655dbb982 291 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 14 65 1.7E-9 T 14-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain LH59_13625 79d2a4cfbcd0e53c63fda06655dbb982 291 Gene3D G3DSA:1.10.3720.10 80 284 3.9E-17 T 14-10-2018 IPR035906 MetI-like superfamily LH59_13625 79d2a4cfbcd0e53c63fda06655dbb982 291 SUPERFAMILY SSF161098 84 269 1.57E-22 T 14-10-2018 IPR035906 MetI-like superfamily LH59_13625 79d2a4cfbcd0e53c63fda06655dbb982 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 288 1.1E-23 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_06525 1e4b2ad393f54a301ed4b09b79d577c4 199 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 187 7.5E-35 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 LH59_06525 1e4b2ad393f54a301ed4b09b79d577c4 199 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 47 78 - T 14-10-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LH59_06525 1e4b2ad393f54a301ed4b09b79d577c4 199 SUPERFAMILY SSF88946 3 104 9.42E-33 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 LH59_06525 1e4b2ad393f54a301ed4b09b79d577c4 199 TIGRFAM TIGR02939 RpoE_Sigma70: RNA polymerase sigma factor RpoE 1 191 5.3E-95 T 14-10-2018 IPR014286 RNA polymerase sigma-70 RpoE type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LH59_06525 1e4b2ad393f54a301ed4b09b79d577c4 199 Gene3D G3DSA:1.10.1740.10 1 122 2.2E-40 T 14-10-2018 LH59_06525 1e4b2ad393f54a301ed4b09b79d577c4 199 Pfam PF08281 Sigma-70, region 4 134 182 6.8E-18 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LH59_06525 1e4b2ad393f54a301ed4b09b79d577c4 199 Gene3D G3DSA:1.10.10.10 123 191 2.6E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_06525 1e4b2ad393f54a301ed4b09b79d577c4 199 SUPERFAMILY SSF88659 125 187 1.33E-17 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like LH59_06525 1e4b2ad393f54a301ed4b09b79d577c4 199 Pfam PF04542 Sigma-70 region 2 25 92 5.1E-19 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 LH59_04135 ea73359a6d4fe5b88a73e0f293c3b88c 184 Hamap MF_00837 Lipid A palmitoyltransferase PagP [pagP]. 1 184 37.489 T 14-10-2018 IPR009746 Antimicrobial peptide resistance/lipid A acylation PagP LH59_04135 ea73359a6d4fe5b88a73e0f293c3b88c 184 ProDom PD103779 CRCA ANTIMICROBIAL RESISTANCE LIPOPROTEIN RCP A PEPTIDE ACYLATION LIPID EXPORTED 36 171 2.0E-61 T 14-10-2018 IPR009746 Antimicrobial peptide resistance/lipid A acylation PagP LH59_04135 ea73359a6d4fe5b88a73e0f293c3b88c 184 SUPERFAMILY SSF56925 26 184 1.26E-68 T 14-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel LH59_04135 ea73359a6d4fe5b88a73e0f293c3b88c 184 Gene3D G3DSA:2.40.160.20 26 184 1.3E-68 T 14-10-2018 LH59_04135 ea73359a6d4fe5b88a73e0f293c3b88c 184 Pfam PF07017 Antimicrobial peptide resistance and lipid A acylation protein PagP 38 181 1.1E-61 T 14-10-2018 IPR009746 Antimicrobial peptide resistance/lipid A acylation PagP LH59_12935 02efb3d39eae0d4d99ff067bf11e7501 371 Pfam PF13458 Periplasmic binding protein 28 366 3.3E-57 T 14-10-2018 IPR028081 Leucine-binding protein domain LH59_12935 02efb3d39eae0d4d99ff067bf11e7501 371 SUPERFAMILY SSF53822 27 367 1.85E-88 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_12935 02efb3d39eae0d4d99ff067bf11e7501 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 91 101 1.1E-32 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 LH59_12935 02efb3d39eae0d4d99ff067bf11e7501 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 29 45 1.1E-32 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 LH59_12935 02efb3d39eae0d4d99ff067bf11e7501 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 258 276 1.1E-32 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 LH59_12935 02efb3d39eae0d4d99ff067bf11e7501 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 332 347 1.1E-32 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 LH59_12935 02efb3d39eae0d4d99ff067bf11e7501 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 281 294 1.1E-32 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 LH59_12935 02efb3d39eae0d4d99ff067bf11e7501 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 70 88 1.1E-32 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 LH59_12935 02efb3d39eae0d4d99ff067bf11e7501 371 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 51 67 1.1E-32 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 LH59_12935 02efb3d39eae0d4d99ff067bf11e7501 371 Gene3D G3DSA:3.40.50.2300 30 348 3.0E-107 T 14-10-2018 LH59_12935 02efb3d39eae0d4d99ff067bf11e7501 371 Gene3D G3DSA:3.40.50.2300 148 276 3.0E-107 T 14-10-2018 LH59_07025 900cd08194aa54001b649d47fd793340 450 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 67 86 1.1E-20 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 LH59_07025 900cd08194aa54001b649d47fd793340 450 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 150 171 1.1E-20 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 LH59_07025 900cd08194aa54001b649d47fd793340 450 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 15 31 1.1E-20 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 LH59_07025 900cd08194aa54001b649d47fd793340 450 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 202 212 1.1E-20 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 LH59_07025 900cd08194aa54001b649d47fd793340 450 SUPERFAMILY SSF52374 4 332 5.35E-81 T 14-10-2018 LH59_07025 900cd08194aa54001b649d47fd793340 450 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 1 332 1.9E-95 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 LH59_07025 900cd08194aa54001b649d47fd793340 450 Gene3D G3DSA:1.10.240.10 197 300 1.1E-114 T 14-10-2018 LH59_07025 900cd08194aa54001b649d47fd793340 450 Gene3D G3DSA:3.40.50.620 4 332 1.1E-114 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LH59_07025 900cd08194aa54001b649d47fd793340 450 Pfam PF00579 tRNA synthetases class I (W and Y) 3 287 1.8E-55 T 14-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 LH59_07025 900cd08194aa54001b649d47fd793340 450 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 2 333 36.762 T 14-10-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 LH59_07025 900cd08194aa54001b649d47fd793340 450 SUPERFAMILY SSF160113 354 406 1.44E-10 T 14-10-2018 IPR036913 YegP-like superfamily LH59_00220 5c2b9e224f8545c6b18d45b341bcde63 128 Pfam PF01042 Endoribonuclease L-PSP 10 115 1.0E-18 T 14-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 LH59_00220 5c2b9e224f8545c6b18d45b341bcde63 128 SUPERFAMILY SSF55298 10 116 5.97E-27 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 LH59_00220 5c2b9e224f8545c6b18d45b341bcde63 128 Gene3D G3DSA:3.30.1330.40 1 119 1.0E-35 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 LH59_20940 5b17022afc0c98e9c6154112394533d1 632 SUPERFAMILY SSF53474 11 385 2.13E-46 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_20940 5b17022afc0c98e9c6154112394533d1 632 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 348 612 5.7E-50 T 14-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 LH59_20940 5b17022afc0c98e9c6154112394533d1 632 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 21 304 1.3E-52 T 14-10-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 LH59_20940 5b17022afc0c98e9c6154112394533d1 632 Gene3D G3DSA:1.10.3020.10 163 251 8.5E-91 T 14-10-2018 LH59_20940 5b17022afc0c98e9c6154112394533d1 632 Gene3D G3DSA:3.40.50.1820 16 361 8.5E-91 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_20940 5b17022afc0c98e9c6154112394533d1 632 SMART SM00939 335 613 1.0E-79 T 14-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 LH59_20940 5b17022afc0c98e9c6154112394533d1 632 Gene3D G3DSA:2.60.120.260 382 617 4.8E-76 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily LH59_20940 5b17022afc0c98e9c6154112394533d1 632 SUPERFAMILY SSF49785 382 614 1.51E-56 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily LH59_20940 5b17022afc0c98e9c6154112394533d1 632 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 17 616 1.6E-104 T 14-10-2018 IPR005674 CocE/Serine esterase GO:0016787 LH59_14520 0ef66fd378633e8ed54e24ebd44a24e1 331 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 9 331 36.342 T 14-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 LH59_14520 0ef66fd378633e8ed54e24ebd44a24e1 331 Pfam PF13353 4Fe-4S single cluster domain 25 112 2.0E-5 T 14-10-2018 LH59_14520 0ef66fd378633e8ed54e24ebd44a24e1 331 SMART SM00729 18 220 5.0E-4 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 LH59_14520 0ef66fd378633e8ed54e24ebd44a24e1 331 Pfam PF04055 Radical SAM superfamily 22 183 3.7E-24 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 LH59_14520 0ef66fd378633e8ed54e24ebd44a24e1 331 SUPERFAMILY SSF102114 8 299 1.83E-65 T 14-10-2018 LH59_14520 0ef66fd378633e8ed54e24ebd44a24e1 331 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 9 331 1.8E-101 T 14-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 LH59_14520 0ef66fd378633e8ed54e24ebd44a24e1 331 Gene3D G3DSA:3.20.20.70 6 331 9.9E-76 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_14520 0ef66fd378633e8ed54e24ebd44a24e1 331 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 24 35 - T 14-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 LH59_14520 0ef66fd378633e8ed54e24ebd44a24e1 331 Pfam PF06463 Molybdenum Cofactor Synthesis C 190 315 2.8E-28 T 14-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 LH59_08655 f38b42cb9f351ea5820f196e79d20c6e 226 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 3 197 23.209 T 14-10-2018 IPR003180 Methylpurine-DNA glycosylase GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 LH59_08655 f38b42cb9f351ea5820f196e79d20c6e 226 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 5 189 3.8E-33 T 14-10-2018 IPR003180 Methylpurine-DNA glycosylase GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 LH59_08655 f38b42cb9f351ea5820f196e79d20c6e 226 SUPERFAMILY SSF50486 1 204 7.85E-50 T 14-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 LH59_08655 f38b42cb9f351ea5820f196e79d20c6e 226 Gene3D G3DSA:3.10.300.10 1 196 5.5E-35 T 14-10-2018 IPR036995 Methylpurine-DNA glycosylase superfamily GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 LH59_02925 817cf35b522978b1d5b0ec8d953c4ceb 265 SMART SM00267 90 261 4.6E-62 T 14-10-2018 IPR000160 GGDEF domain LH59_02925 817cf35b522978b1d5b0ec8d953c4ceb 265 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 97 259 2.2E-49 T 14-10-2018 IPR000160 GGDEF domain LH59_02925 817cf35b522978b1d5b0ec8d953c4ceb 265 Gene3D G3DSA:3.30.70.270 95 261 5.6E-57 T 14-10-2018 LH59_02925 817cf35b522978b1d5b0ec8d953c4ceb 265 Pfam PF00990 Diguanylate cyclase, GGDEF domain 103 257 2.2E-45 T 14-10-2018 IPR000160 GGDEF domain LH59_02925 817cf35b522978b1d5b0ec8d953c4ceb 265 SUPERFAMILY SSF55073 106 259 7.45E-49 T 14-10-2018 IPR029787 Nucleotide cyclase LH59_07750 b0533ccbb330636aac41172d4d48a391 273 Pfam PF13419 Haloacid dehalogenase-like hydrolase 13 207 3.3E-11 T 14-10-2018 LH59_07750 b0533ccbb330636aac41172d4d48a391 273 Hamap MF_01375 Phosphonoacetaldehyde hydrolase [phnX]. 1 273 128.734 T 14-10-2018 IPR006323 Phosphonoacetaldehyde hydrolase GO:0019700|GO:0050194 KEGG: 00440+3.11.1.1 LH59_07750 b0533ccbb330636aac41172d4d48a391 273 Gene3D G3DSA:3.40.50.1000 12 273 2.3E-96 T 14-10-2018 IPR023214 HAD superfamily LH59_07750 b0533ccbb330636aac41172d4d48a391 273 SUPERFAMILY SSF56784 10 263 3.16E-60 T 14-10-2018 IPR036412 HAD-like superfamily LH59_07750 b0533ccbb330636aac41172d4d48a391 273 TIGRFAM TIGR01422 phosphonatase: phosphonoacetaldehyde hydrolase 9 261 3.6E-110 T 14-10-2018 IPR006323 Phosphonoacetaldehyde hydrolase GO:0019700|GO:0050194 KEGG: 00440+3.11.1.1 LH59_07750 b0533ccbb330636aac41172d4d48a391 273 Gene3D G3DSA:1.10.150.240 28 105 2.3E-96 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 LH59_07750 b0533ccbb330636aac41172d4d48a391 273 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 96 207 3.8E-13 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 LH59_04120 1451a757f95498042687c1b30669b19e 259 Pfam PF00106 short chain dehydrogenase 8 193 1.4E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_04120 1451a757f95498042687c1b30669b19e 259 Gene3D G3DSA:3.40.50.720 1 258 5.0E-61 T 14-10-2018 LH59_04120 1451a757f95498042687c1b30669b19e 259 SUPERFAMILY SSF51735 7 253 2.85E-59 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_04120 1451a757f95498042687c1b30669b19e 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 1.8E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_04120 1451a757f95498042687c1b30669b19e 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.8E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_04120 1451a757f95498042687c1b30669b19e 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.8E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_04120 1451a757f95498042687c1b30669b19e 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.8E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_04120 1451a757f95498042687c1b30669b19e 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.8E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_04120 1451a757f95498042687c1b30669b19e 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.8E-24 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_26615 a5d5cfae282593e113249ec7a8cce24f 329 Gene3D G3DSA:3.10.580.10 201 326 9.3E-40 T 14-10-2018 LH59_26615 a5d5cfae282593e113249ec7a8cce24f 329 Gene3D G3DSA:3.40.50.10490 7 200 4.1E-62 T 14-10-2018 LH59_26615 a5d5cfae282593e113249ec7a8cce24f 329 Pfam PF00571 CBS domain 215 263 6.6E-5 T 14-10-2018 IPR000644 CBS domain LH59_26615 a5d5cfae282593e113249ec7a8cce24f 329 Pfam PF00571 CBS domain 277 326 9.4E-6 T 14-10-2018 IPR000644 CBS domain LH59_26615 a5d5cfae282593e113249ec7a8cce24f 329 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 50 319 3.1E-101 T 14-10-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 LH59_26615 a5d5cfae282593e113249ec7a8cce24f 329 Pfam PF01380 SIS domain 45 177 2.2E-29 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 LH59_26615 a5d5cfae282593e113249ec7a8cce24f 329 SMART SM00116 215 263 0.17 T 14-10-2018 IPR000644 CBS domain LH59_26615 a5d5cfae282593e113249ec7a8cce24f 329 SMART SM00116 280 328 10.0 T 14-10-2018 IPR000644 CBS domain LH59_26615 a5d5cfae282593e113249ec7a8cce24f 329 PIRSF PIRSF004692 1 329 6.4E-126 T 14-10-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 LH59_26615 a5d5cfae282593e113249ec7a8cce24f 329 SUPERFAMILY SSF53697 17 327 3.34E-63 T 14-10-2018 LH59_21670 97b798a529a44ea316069be294a6fe50 74 Gene3D G3DSA:2.30.30.320 3 74 2.1E-15 T 14-10-2018 IPR037135 DUF1653-like domain superfamily LH59_21670 97b798a529a44ea316069be294a6fe50 74 Pfam PF07866 Protein of unknown function (DUF1653) 11 68 1.1E-18 T 14-10-2018 IPR023387 DUF1653-like domain LH59_00950 346009d3ee3a5ee828cd4c4a63c5a4cf 232 Gene3D G3DSA:3.40.50.880 1 231 4.4E-72 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_00950 346009d3ee3a5ee828cd4c4a63c5a4cf 232 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 3 230 33.881 T 14-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 LH59_00950 346009d3ee3a5ee828cd4c4a63c5a4cf 232 Pfam PF00117 Glutamine amidotransferase class-I 6 227 4.9E-17 T 14-10-2018 IPR017926 Glutamine amidotransferase LH59_00950 346009d3ee3a5ee828cd4c4a63c5a4cf 232 SUPERFAMILY SSF52317 3 230 2.64E-52 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_00950 346009d3ee3a5ee828cd4c4a63c5a4cf 232 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 141 229 5.2E-31 T 14-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 LH59_00950 346009d3ee3a5ee828cd4c4a63c5a4cf 232 PIRSF PIRSF000495 130 232 3.5E-29 T 14-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 LH59_00950 346009d3ee3a5ee828cd4c4a63c5a4cf 232 PIRSF PIRSF000495 2 119 5.6E-33 T 14-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 LH59_26885 efbb8bf072af75ea0dfffe39f79c8be3 265 SMART SM00382 28 220 8.1E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_26885 efbb8bf072af75ea0dfffe39f79c8be3 265 SUPERFAMILY SSF52540 2 242 1.55E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_26885 efbb8bf072af75ea0dfffe39f79c8be3 265 Pfam PF00005 ABC transporter 19 170 6.3E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_26885 efbb8bf072af75ea0dfffe39f79c8be3 265 Gene3D G3DSA:3.40.50.300 1 244 1.1E-51 T 14-10-2018 LH59_04805 2f20e2a3e7d414de2d225b3181df413c 319 SUPERFAMILY SSF46785 7 116 4.38E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_04805 2f20e2a3e7d414de2d225b3181df413c 319 Gene3D G3DSA:1.10.10.10 6 93 7.6E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_04805 2f20e2a3e7d414de2d225b3181df413c 319 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 66 3.4E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_04805 2f20e2a3e7d414de2d225b3181df413c 319 SUPERFAMILY SSF53850 92 316 4.16E-28 T 14-10-2018 LH59_04805 2f20e2a3e7d414de2d225b3181df413c 319 Pfam PF03466 LysR substrate binding domain 91 314 4.8E-24 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_04805 2f20e2a3e7d414de2d225b3181df413c 319 Gene3D G3DSA:3.40.190.290 95 313 5.3E-39 T 14-10-2018 LH59_26645 531d894b014e8b642a8206673dd53b61 151 SUPERFAMILY SSF55804 1 146 6.41E-41 T 14-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 LH59_26645 531d894b014e8b642a8206673dd53b61 151 Gene3D G3DSA:3.40.930.10 1 150 6.8E-50 T 14-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 LH59_26645 531d894b014e8b642a8206673dd53b61 151 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 8 147 3.4E-31 T 14-10-2018 IPR002178 PTS EIIA type-2 domain LH59_26645 531d894b014e8b642a8206673dd53b61 151 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 52 68 - T 14-10-2018 IPR002178 PTS EIIA type-2 domain LH59_09940 814c75076773b73aa45ff109d7ca4041 639 SUPERFAMILY SSF53474 382 638 4.27E-72 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_09940 814c75076773b73aa45ff109d7ca4041 639 Gene3D G3DSA:3.40.50.1820 335 639 2.7E-81 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_09940 814c75076773b73aa45ff109d7ca4041 639 SUPERFAMILY SSF50993 61 367 1.86E-14 T 14-10-2018 LH59_09940 814c75076773b73aa45ff109d7ca4041 639 Pfam PF00326 Prolyl oligopeptidase family 427 638 7.7E-47 T 14-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 LH59_09940 814c75076773b73aa45ff109d7ca4041 639 Gene3D G3DSA:2.120.10.30 28 239 3.7E-6 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like LH59_24940 1dbfa0e118d7b463a015e6f014e323b4 112 Pfam PF13698 Domain of unknown function (DUF4156) 19 111 1.3E-31 T 14-10-2018 IPR025294 Protein of unknown function DUF4156 LH59_02095 00d4c901ed1d7b5ff9ba6a86fc4839e8 301 SUPERFAMILY SSF53474 32 271 3.49E-18 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_02095 00d4c901ed1d7b5ff9ba6a86fc4839e8 301 Gene3D G3DSA:3.40.50.1820 1 301 1.9E-102 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_00305 6cef4024244c20262bee5f51521d3240 156 SUPERFAMILY SSF46785 2 63 3.27E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_00305 6cef4024244c20262bee5f51521d3240 156 Gene3D G3DSA:3.30.70.920 57 140 4.2E-24 T 14-10-2018 LH59_00305 6cef4024244c20262bee5f51521d3240 156 Gene3D G3DSA:1.10.10.10 1 56 4.2E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_00305 6cef4024244c20262bee5f51521d3240 156 SUPERFAMILY SSF54909 66 147 4.29E-21 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel LH59_00305 6cef4024244c20262bee5f51521d3240 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 1.7E-14 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_00305 6cef4024244c20262bee5f51521d3240 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 1.7E-14 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_00305 6cef4024244c20262bee5f51521d3240 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 1.7E-14 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_00305 6cef4024244c20262bee5f51521d3240 156 Pfam PF13404 AsnC-type helix-turn-helix domain 3 44 2.1E-17 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_00305 6cef4024244c20262bee5f51521d3240 156 Pfam PF01037 Lrp/AsnC ligand binding domain 69 142 3.2E-24 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LH59_00305 6cef4024244c20262bee5f51521d3240 156 SMART SM00344 3 112 1.1E-41 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 LH59_00305 6cef4024244c20262bee5f51521d3240 156 ProSitePatterns PS00519 AsnC-type HTH domain signature. 21 47 - T 14-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site LH59_22985 e47c5feae3268b7de1c7913d83b4df52 460 SUPERFAMILY SSF55874 314 454 3.41E-28 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_22985 e47c5feae3268b7de1c7913d83b4df52 460 SMART SM00387 350 457 9.6E-25 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_22985 e47c5feae3268b7de1c7913d83b4df52 460 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 350 455 6.0E-15 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_22985 e47c5feae3268b7de1c7913d83b4df52 460 Gene3D G3DSA:3.30.565.10 311 456 9.6E-30 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_22985 e47c5feae3268b7de1c7913d83b4df52 460 PRINTS PR00344 Bacterial sensor protein C-terminal signature 417 435 1.3E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_22985 e47c5feae3268b7de1c7913d83b4df52 460 PRINTS PR00344 Bacterial sensor protein C-terminal signature 441 454 1.3E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_22985 e47c5feae3268b7de1c7913d83b4df52 460 PRINTS PR00344 Bacterial sensor protein C-terminal signature 404 414 1.3E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_22985 e47c5feae3268b7de1c7913d83b4df52 460 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 400 1.3E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_06450 30214f50e862067b48f798186043b209 221 Gene3D G3DSA:3.40.50.1000 6 204 1.4E-54 T 14-10-2018 IPR023214 HAD superfamily LH59_06450 30214f50e862067b48f798186043b209 221 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 91 177 2.0E-10 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 LH59_06450 30214f50e862067b48f798186043b209 221 Gene3D G3DSA:1.10.150.240 18 83 1.4E-54 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 LH59_06450 30214f50e862067b48f798186043b209 221 SUPERFAMILY SSF56784 1 213 1.58E-57 T 14-10-2018 IPR036412 HAD-like superfamily LH59_06450 30214f50e862067b48f798186043b209 221 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 182 2.8E-35 T 14-10-2018 LH59_06450 30214f50e862067b48f798186043b209 221 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 119 182 1.1E-7 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 LH59_04740 b32efd67283e01ee047a319e93834265 278 SUPERFAMILY SSF69572 12 277 1.15E-55 T 14-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 LH59_04740 b32efd67283e01ee047a319e93834265 278 Pfam PF00899 ThiF family 21 274 4.8E-32 T 14-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 LH59_04740 b32efd67283e01ee047a319e93834265 278 Gene3D G3DSA:3.40.50.720 6 278 5.5E-86 T 14-10-2018 LH59_20305 1e7b14b97763dc363fbfba8f6fd472c0 325 Gene3D G3DSA:1.20.59.20 227 314 1.6E-8 T 14-10-2018 LH59_20305 1e7b14b97763dc363fbfba8f6fd472c0 325 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 1 304 21.287 T 14-10-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 LH59_20305 1e7b14b97763dc363fbfba8f6fd472c0 325 Gene3D G3DSA:3.40.50.620 1 225 7.1E-63 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LH59_20305 1e7b14b97763dc363fbfba8f6fd472c0 325 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 8 194 5.8E-42 T 14-10-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 LH59_20305 1e7b14b97763dc363fbfba8f6fd472c0 325 SUPERFAMILY SSF82829 238 315 8.76E-19 T 14-10-2018 LH59_20305 1e7b14b97763dc363fbfba8f6fd472c0 325 SUPERFAMILY SSF52402 3 224 1.37E-49 T 14-10-2018 LH59_20305 1e7b14b97763dc363fbfba8f6fd472c0 325 Pfam PF09179 TilS substrate binding domain 243 312 3.8E-14 T 14-10-2018 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 LH59_20305 1e7b14b97763dc363fbfba8f6fd472c0 325 Pfam PF01171 PP-loop family 8 191 8.1E-46 T 14-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 LH59_07680 5732269a253ce96df5ec612abbb2b658 208 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 17 190 1.5E-43 T 14-10-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG LH59_07680 5732269a253ce96df5ec612abbb2b658 208 Pfam PF03641 Possible lysine decarboxylase 59 189 1.4E-32 T 14-10-2018 IPR031100 LOG family LH59_07680 5732269a253ce96df5ec612abbb2b658 208 Gene3D G3DSA:3.40.50.450 3 205 3.4E-61 T 14-10-2018 LH59_07680 5732269a253ce96df5ec612abbb2b658 208 SUPERFAMILY SSF102405 9 188 3.97E-56 T 14-10-2018 LH59_07440 559672de371cddc3ed339cf11cc03124 290 Gene3D G3DSA:1.10.3730.20 35 142 3.2E-7 T 14-10-2018 LH59_07440 559672de371cddc3ed339cf11cc03124 290 SUPERFAMILY SSF103481 39 141 9.42E-13 T 14-10-2018 LH59_07440 559672de371cddc3ed339cf11cc03124 290 Pfam PF00892 EamA-like transporter family 153 287 7.9E-8 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_07440 559672de371cddc3ed339cf11cc03124 290 SUPERFAMILY SSF103481 211 287 1.57E-10 T 14-10-2018 LH59_19180 89afe734b1da79eac3b03c2abedb6a20 340 PIRSF PIRSF006470 7 337 3.0E-69 T 14-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 LH59_19180 89afe734b1da79eac3b03c2abedb6a20 340 TIGRFAM TIGR00787 dctP: TRAP transporter solute receptor, DctP family 40 293 2.8E-71 T 14-10-2018 IPR004682 TRAP transporter solute receptor, DctP family GO:0030288|GO:0055085 LH59_19180 89afe734b1da79eac3b03c2abedb6a20 340 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 40 311 1.7E-70 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 LH59_19180 89afe734b1da79eac3b03c2abedb6a20 340 Gene3D G3DSA:3.40.190.170 32 340 5.0E-106 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily LH59_23290 9d4da060e0fe1264c2b49005704f3b66 236 Pfam PF01476 LysM domain 34 76 2.6E-15 T 14-10-2018 IPR018392 LysM domain LH59_23290 9d4da060e0fe1264c2b49005704f3b66 236 SUPERFAMILY SSF51261 33 231 8.37E-44 T 14-10-2018 IPR011055 Duplicated hybrid motif LH59_23290 9d4da060e0fe1264c2b49005704f3b66 236 Pfam PF01551 Peptidase family M23 136 229 1.0E-27 T 14-10-2018 IPR016047 Peptidase M23 LH59_23290 9d4da060e0fe1264c2b49005704f3b66 236 Gene3D G3DSA:2.70.70.10 103 233 1.3E-31 T 14-10-2018 IPR011055 Duplicated hybrid motif LH59_23290 9d4da060e0fe1264c2b49005704f3b66 236 Gene3D G3DSA:3.10.350.10 23 92 1.4E-17 T 14-10-2018 IPR036779 LysM domain superfamily LH59_23290 9d4da060e0fe1264c2b49005704f3b66 236 SMART SM00257 33 77 1.0E-14 T 14-10-2018 IPR018392 LysM domain LH59_27180 ea2dc7f4b8f4fec67056464320204725 376 SUPERFAMILY SSF90002 280 374 1.44E-25 T 14-10-2018 LH59_27180 ea2dc7f4b8f4fec67056464320204725 376 SMART SM00833 280 374 3.8E-18 T 14-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal LH59_27180 ea2dc7f4b8f4fec67056464320204725 376 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 12 193 4.5E-51 T 14-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain LH59_27180 ea2dc7f4b8f4fec67056464320204725 376 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 280 374 6.6E-22 T 14-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal LH59_27180 ea2dc7f4b8f4fec67056464320204725 376 Gene3D G3DSA:3.40.50.300 8 212 1.5E-69 T 14-10-2018 LH59_27180 ea2dc7f4b8f4fec67056464320204725 376 SUPERFAMILY SSF52540 12 216 1.05E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_27180 ea2dc7f4b8f4fec67056464320204725 376 Gene3D G3DSA:3.30.1220.10 262 374 6.3E-33 T 14-10-2018 IPR036627 CobW-like, C-terminal domain superfamily LH59_24905 40f3b7b9f8962c28d05140de11006fbe 245 SUPERFAMILY SSF52821 96 235 7.46E-26 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily LH59_24905 40f3b7b9f8962c28d05140de11006fbe 245 Hamap MF_00469 UPF0176 protein YceA [yceA]. 2 245 32.966 T 14-10-2018 IPR020936 Uncharacterised protein family UPF0176 LH59_24905 40f3b7b9f8962c28d05140de11006fbe 245 Pfam PF00581 Rhodanese-like domain 119 214 7.5E-6 T 14-10-2018 IPR001763 Rhodanese-like domain LH59_24905 40f3b7b9f8962c28d05140de11006fbe 245 SMART SM00450 119 220 1.3E-9 T 14-10-2018 IPR001763 Rhodanese-like domain LH59_24905 40f3b7b9f8962c28d05140de11006fbe 245 Gene3D G3DSA:3.30.70.100 1 96 2.9E-29 T 14-10-2018 LH59_24905 40f3b7b9f8962c28d05140de11006fbe 245 Gene3D G3DSA:3.40.250.10 99 244 4.3E-34 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily LH59_17735 5294993e084f5c2079e828d4d354524e 255 SMART SM00346 1 91 0.0018 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_17735 5294993e084f5c2079e828d4d354524e 255 SUPERFAMILY SSF46785 4 65 1.32E-9 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_17735 5294993e084f5c2079e828d4d354524e 255 SUPERFAMILY SSF55781 76 248 4.12E-31 T 14-10-2018 LH59_17735 5294993e084f5c2079e828d4d354524e 255 Gene3D G3DSA:1.10.10.10 3 62 6.1E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_17735 5294993e084f5c2079e828d4d354524e 255 Gene3D G3DSA:3.30.450.40 73 250 7.6E-29 T 14-10-2018 IPR029016 GAF-like domain superfamily LH59_17735 5294993e084f5c2079e828d4d354524e 255 Pfam PF01614 Bacterial transcriptional regulator 126 237 2.5E-7 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal LH59_17735 5294993e084f5c2079e828d4d354524e 255 Pfam PF09339 IclR helix-turn-helix domain 9 53 6.4E-11 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_18320 332019962db60829cd12a30b4b68f74a 331 SUPERFAMILY SSF53850 119 297 1.26E-10 T 14-10-2018 LH59_18320 332019962db60829cd12a30b4b68f74a 331 PIRSF PIRSF017082 2 330 1.2E-71 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_18320 332019962db60829cd12a30b4b68f74a 331 Gene3D G3DSA:3.40.190.150 37 321 3.2E-99 T 14-10-2018 LH59_18320 332019962db60829cd12a30b4b68f74a 331 Gene3D G3DSA:3.40.190.10 133 256 3.2E-99 T 14-10-2018 LH59_18320 332019962db60829cd12a30b4b68f74a 331 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 55 327 1.4E-76 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_02695 5eb57dde317e7c378e52312836a7987a 391 Gene3D G3DSA:3.40.50.2300 144 360 3.4E-85 T 14-10-2018 LH59_02695 5eb57dde317e7c378e52312836a7987a 391 SUPERFAMILY SSF53822 27 388 7.74E-76 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_02695 5eb57dde317e7c378e52312836a7987a 391 Pfam PF13458 Periplasmic binding protein 27 364 6.9E-66 T 14-10-2018 IPR028081 Leucine-binding protein domain LH59_02695 5eb57dde317e7c378e52312836a7987a 391 Gene3D G3DSA:3.40.50.2300 30 354 3.4E-85 T 14-10-2018 LH59_26025 1f6d5507d8faa4ec458dccf528685372 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 180 3.4E-4 T 14-10-2018 LH59_26025 1f6d5507d8faa4ec458dccf528685372 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.5E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_26025 1f6d5507d8faa4ec458dccf528685372 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 1.5E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_26025 1f6d5507d8faa4ec458dccf528685372 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 1.5E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_26025 1f6d5507d8faa4ec458dccf528685372 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 203 223 1.5E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_26025 1f6d5507d8faa4ec458dccf528685372 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.5E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_26025 1f6d5507d8faa4ec458dccf528685372 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 1.5E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_26025 1f6d5507d8faa4ec458dccf528685372 246 Gene3D G3DSA:3.40.50.720 6 242 7.1E-75 T 14-10-2018 LH59_26025 1f6d5507d8faa4ec458dccf528685372 246 SUPERFAMILY SSF51735 9 241 1.17E-74 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_26025 1f6d5507d8faa4ec458dccf528685372 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 238 4.8E-56 T 14-10-2018 LH59_26025 1f6d5507d8faa4ec458dccf528685372 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 1.7E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_26025 1f6d5507d8faa4ec458dccf528685372 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 1.7E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_26025 1f6d5507d8faa4ec458dccf528685372 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 1.7E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_17775 e32bf83ce845cb52f919128e614d5350 217 SUPERFAMILY SSF161098 14 200 1.96E-43 T 14-10-2018 IPR035906 MetI-like superfamily LH59_17775 e32bf83ce845cb52f919128e614d5350 217 Gene3D G3DSA:1.10.3720.10 5 216 3.5E-54 T 14-10-2018 IPR035906 MetI-like superfamily LH59_17775 e32bf83ce845cb52f919128e614d5350 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 215 5.9E-20 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_17775 e32bf83ce845cb52f919128e614d5350 217 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 109 8.4E-28 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 LH59_17775 e32bf83ce845cb52f919128e614d5350 217 TIGRFAM TIGR03004 ectoine_ehuC: ectoine/hydroxyectoine ABC transporter, permease protein EhuC 10 215 1.3E-80 T 14-10-2018 IPR014342 Ectoine/hydroxyectoine ABC transporter, permease protein EhuC LH59_01145 a934ab37a56252eaa22c848de6ded5b6 291 SUPERFAMILY SSF81452 13 290 7.33E-79 T 14-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_01145 a934ab37a56252eaa22c848de6ded5b6 291 Pfam PF00510 Cytochrome c oxidase subunit III 16 291 8.5E-58 T 14-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_01145 a934ab37a56252eaa22c848de6ded5b6 291 Gene3D G3DSA:1.20.120.80 79 291 4.0E-68 T 14-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_01145 a934ab37a56252eaa22c848de6ded5b6 291 Gene3D G3DSA:1.10.287.70 7 78 1.5E-12 T 14-10-2018 LH59_10815 228728ddd6e1e2488eba1c57bcf7c71f 395 Gene3D G3DSA:3.50.50.60 5 363 4.0E-91 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_10815 228728ddd6e1e2488eba1c57bcf7c71f 395 Pfam PF01266 FAD dependent oxidoreductase 5 360 1.1E-53 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 LH59_10815 228728ddd6e1e2488eba1c57bcf7c71f 395 SUPERFAMILY SSF51905 4 387 6.09E-57 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_10815 228728ddd6e1e2488eba1c57bcf7c71f 395 Gene3D G3DSA:3.30.9.10 88 325 4.0E-91 T 14-10-2018 LH59_09430 1af041f843e9bb76a01074641b273c4e 358 Gene3D G3DSA:3.40.718.10 1 357 8.2E-156 T 14-10-2018 LH59_09430 1af041f843e9bb76a01074641b273c4e 358 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 3 357 51.483 T 14-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 LH59_09430 1af041f843e9bb76a01074641b273c4e 358 SUPERFAMILY SSF53659 1 357 2.16E-122 T 14-10-2018 LH59_09430 1af041f843e9bb76a01074641b273c4e 358 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 4 353 2.9E-133 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 LH59_09430 1af041f843e9bb76a01074641b273c4e 358 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 4 352 2.7E-149 T 14-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 LH59_09430 1af041f843e9bb76a01074641b273c4e 358 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 244 263 - T 14-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 LH59_09430 1af041f843e9bb76a01074641b273c4e 358 SMART SM01329 4 353 2.8E-207 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 LH59_14620 67f1b64e8c55aae60f29326529e35a88 666 Pfam PF03477 ATP cone domain 5 92 1.6E-19 T 14-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 LH59_14620 67f1b64e8c55aae60f29326529e35a88 666 TIGRFAM TIGR02487 NrdD: anaerobic ribonucleoside-triphosphate reductase 121 654 8.9E-139 T 14-10-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.1.98.6|KEGG: 00240+1.1.98.6|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 LH59_14620 67f1b64e8c55aae60f29326529e35a88 666 SUPERFAMILY SSF51998 122 654 1.25E-155 T 14-10-2018 LH59_14620 67f1b64e8c55aae60f29326529e35a88 666 Gene3D G3DSA:3.20.70.20 134 661 5.0E-108 T 14-10-2018 LH59_14620 67f1b64e8c55aae60f29326529e35a88 666 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 122 653 1.3E-170 T 14-10-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.1.98.6|KEGG: 00240+1.1.98.6|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 LH59_01755 79eb35acc510dd1ca85a52472a32cc2b 344 Pfam PF00535 Glycosyl transferase family 2 12 138 1.1E-25 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 LH59_01755 79eb35acc510dd1ca85a52472a32cc2b 344 SUPERFAMILY SSF53448 9 239 4.5E-44 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases LH59_01755 79eb35acc510dd1ca85a52472a32cc2b 344 Gene3D G3DSA:3.90.550.10 7 209 8.5E-37 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases LH59_27650 f0ad5e8900ed97f8e95db0bc0e416f01 358 Gene3D G3DSA:1.20.1090.10 172 357 1.7E-60 T 14-10-2018 LH59_27650 f0ad5e8900ed97f8e95db0bc0e416f01 358 Gene3D G3DSA:3.40.50.1970 1 171 5.1E-61 T 14-10-2018 LH59_27650 f0ad5e8900ed97f8e95db0bc0e416f01 358 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 1 358 70.571 T 14-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 LH59_27650 f0ad5e8900ed97f8e95db0bc0e416f01 358 PIRSF PIRSF001455 16 357 2.6E-107 T 14-10-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 LH59_27650 f0ad5e8900ed97f8e95db0bc0e416f01 358 Pfam PF01761 3-dehydroquinate synthase 66 323 2.0E-105 T 14-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 LH59_27650 f0ad5e8900ed97f8e95db0bc0e416f01 358 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 13 343 1.5E-114 T 14-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 LH59_27650 f0ad5e8900ed97f8e95db0bc0e416f01 358 SUPERFAMILY SSF56796 10 353 3.14E-110 T 14-10-2018 LH59_07855 9d0275b2472ed545e74fd82ef33dd302 152 Pfam PF13404 AsnC-type helix-turn-helix domain 5 46 4.9E-14 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_07855 9d0275b2472ed545e74fd82ef33dd302 152 Gene3D G3DSA:3.30.70.920 62 148 3.1E-19 T 14-10-2018 LH59_07855 9d0275b2472ed545e74fd82ef33dd302 152 SUPERFAMILY SSF46785 4 59 2.92E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_07855 9d0275b2472ed545e74fd82ef33dd302 152 Pfam PF01037 Lrp/AsnC ligand binding domain 73 141 1.2E-17 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LH59_07855 9d0275b2472ed545e74fd82ef33dd302 152 SUPERFAMILY SSF54909 67 146 1.02E-17 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel LH59_07855 9d0275b2472ed545e74fd82ef33dd302 152 SMART SM00344 5 111 2.4E-22 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 LH59_07855 9d0275b2472ed545e74fd82ef33dd302 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 4.5E-11 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_07855 9d0275b2472ed545e74fd82ef33dd302 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 4.5E-11 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_07855 9d0275b2472ed545e74fd82ef33dd302 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 4.5E-11 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_07855 9d0275b2472ed545e74fd82ef33dd302 152 Gene3D G3DSA:1.10.10.10 1 59 1.4E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_11990 b5de3e20c792660f668ee1aa36aa1250 283 Pfam PF02517 CAAX protease self-immunity 177 268 1.3E-21 T 14-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 LH59_25360 f74350b7c4c29ce40d2597f368efd5f1 468 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 453 33.326 T 14-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 LH59_25360 f74350b7c4c29ce40d2597f368efd5f1 468 SMART SM00382 103 283 7.0E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_25360 f74350b7c4c29ce40d2597f368efd5f1 468 Pfam PF00448 SRP54-type protein, GTPase domain 104 308 7.9E-68 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 LH59_25360 f74350b7c4c29ce40d2597f368efd5f1 468 Gene3D G3DSA:1.20.120.140 4 319 2.0E-119 T 14-10-2018 LH59_25360 f74350b7c4c29ce40d2597f368efd5f1 468 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 282 295 - T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 LH59_25360 f74350b7c4c29ce40d2597f368efd5f1 468 Pfam PF02978 Signal peptide binding domain 341 441 2.3E-31 T 14-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 LH59_25360 f74350b7c4c29ce40d2597f368efd5f1 468 SMART SM00962 104 309 4.1E-112 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 LH59_25360 f74350b7c4c29ce40d2597f368efd5f1 468 SUPERFAMILY SSF52540 42 370 3.72E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_25360 f74350b7c4c29ce40d2597f368efd5f1 468 SMART SM00963 1 86 4.7E-33 T 14-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 LH59_25360 f74350b7c4c29ce40d2597f368efd5f1 468 SUPERFAMILY SSF47446 311 445 9.03E-44 T 14-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 LH59_25360 f74350b7c4c29ce40d2597f368efd5f1 468 Gene3D G3DSA:1.10.260.30 341 466 3.8E-41 T 14-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 LH59_25360 f74350b7c4c29ce40d2597f368efd5f1 468 Gene3D G3DSA:3.40.50.300 95 298 2.0E-119 T 14-10-2018 LH59_25360 f74350b7c4c29ce40d2597f368efd5f1 468 TIGRFAM TIGR00959 ffh: signal recognition particle protein 3 443 1.3E-169 T 14-10-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 LH59_25360 f74350b7c4c29ce40d2597f368efd5f1 468 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 3.2E-19 T 14-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 LH59_00365 084250f734d967b656bfe04c13c691aa 379 Gene3D G3DSA:2.40.37.20 24 375 4.9E-146 T 14-10-2018 LH59_00365 084250f734d967b656bfe04c13c691aa 379 SMART SM01119 274 362 2.3E-31 T 14-10-2018 IPR026956 D-serine dehydratase-like domain LH59_00365 084250f734d967b656bfe04c13c691aa 379 Pfam PF14031 Putative serine dehydratase domain 274 360 2.2E-20 T 14-10-2018 IPR026956 D-serine dehydratase-like domain LH59_00365 084250f734d967b656bfe04c13c691aa 379 SUPERFAMILY SSF51419 31 263 5.23E-42 T 14-10-2018 IPR029066 PLP-binding barrel LH59_00365 084250f734d967b656bfe04c13c691aa 379 Gene3D G3DSA:3.20.20.10 33 255 4.9E-146 T 14-10-2018 IPR029066 PLP-binding barrel LH59_00365 084250f734d967b656bfe04c13c691aa 379 Pfam PF01168 Alanine racemase, N-terminal domain 31 257 2.4E-29 T 14-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LH59_11300 a3b3708f79bd57f5a68d4ca7f38b8d19 193 PIRSF PIRSF003159 1 184 9.6E-82 T 14-10-2018 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 LH59_11300 a3b3708f79bd57f5a68d4ca7f38b8d19 193 SUPERFAMILY SSF160930 6 163 6.67E-60 T 14-10-2018 LH59_11300 a3b3708f79bd57f5a68d4ca7f38b8d19 193 Pfam PF05280 Flagellar transcriptional activator (FlhC) 1 175 8.0E-82 T 14-10-2018 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 LH59_11300 a3b3708f79bd57f5a68d4ca7f38b8d19 193 ProDom PD016592 ACTIVATOR TRANSCRIPTIONAL FLAGELLUM FLAGELLAR TRANSCRIPTION FLHC RNA DNA-BINDING REGULATION DNA-DIRECTED 1 163 1.0E-83 T 14-10-2018 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 LH59_11300 a3b3708f79bd57f5a68d4ca7f38b8d19 193 Hamap MF_01891 Flagellar transcriptional regulator FlhC [flhC]. 1 190 45.113 T 14-10-2018 IPR007944 Flagellar transcriptional activator FlhC GO:0003677|GO:0045893|GO:1902208 LH59_06960 340cf7e8ec7b79514b0053a07a248f8f 338 TIGRFAM TIGR01274 ACC_deam: 1-aminocyclopropane-1-carboxylate deaminase 3 337 2.2E-185 T 14-10-2018 IPR005965 1-aminocyclopropane-1-carboxylate deaminase GO:0008660|GO:0009310|GO:0030170 KEGG: 00270+3.5.99.7 LH59_06960 340cf7e8ec7b79514b0053a07a248f8f 338 PIRSF PIRSF006278 1 337 9.8E-126 T 14-10-2018 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase LH59_06960 340cf7e8ec7b79514b0053a07a248f8f 338 SUPERFAMILY SSF53686 4 334 2.33E-102 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme LH59_06960 340cf7e8ec7b79514b0053a07a248f8f 338 Gene3D G3DSA:3.40.50.1100 67 165 1.6E-122 T 14-10-2018 LH59_06960 340cf7e8ec7b79514b0053a07a248f8f 338 Gene3D G3DSA:3.40.50.1100 8 328 1.6E-122 T 14-10-2018 LH59_06960 340cf7e8ec7b79514b0053a07a248f8f 338 Hamap MF_00807 1-aminocyclopropane-1-carboxylate deaminase [acdS]. 2 338 71.043 T 14-10-2018 IPR020601 1-aminocyclopropane-1-carboxylate deaminase, bacterial GO:0008660|GO:0009310|GO:0030170 KEGG: 00270+3.5.99.7 LH59_06960 340cf7e8ec7b79514b0053a07a248f8f 338 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 12 321 4.0E-48 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme LH59_21240 8fe8b89b1755824a33a4434486c46745 264 TIGRFAM TIGR00637 ModE_repress: ModE molybdate transport repressor domain 19 106 2.3E-29 T 14-10-2018 IPR003725 Molybdenum-binding protein ModE, N-terminal LH59_21240 8fe8b89b1755824a33a4434486c46745 264 SUPERFAMILY SSF50331 123 191 1.51E-21 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal LH59_21240 8fe8b89b1755824a33a4434486c46745 264 Gene3D G3DSA:2.40.50.100 193 263 2.3E-26 T 14-10-2018 LH59_21240 8fe8b89b1755824a33a4434486c46745 264 Gene3D G3DSA:2.40.50.100 121 192 9.0E-26 T 14-10-2018 LH59_21240 8fe8b89b1755824a33a4434486c46745 264 SUPERFAMILY SSF46785 2 104 2.45E-25 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_21240 8fe8b89b1755824a33a4434486c46745 264 PIRSF PIRSF005763 1 264 3.5E-98 T 14-10-2018 IPR016462 Molybdate-dependent transcriptional regulator ModE GO:0006355|GO:0015689|GO:0030151 LH59_21240 8fe8b89b1755824a33a4434486c46745 264 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 21 84 4.1E-15 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_21240 8fe8b89b1755824a33a4434486c46745 264 Gene3D G3DSA:1.10.10.10 1 113 4.2E-33 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_21240 8fe8b89b1755824a33a4434486c46745 264 Pfam PF03459 TOBE domain 125 188 1.6E-16 T 14-10-2018 IPR005116 Transport-associated OB, type 1 LH59_21240 8fe8b89b1755824a33a4434486c46745 264 Pfam PF03459 TOBE domain 198 260 5.4E-18 T 14-10-2018 IPR005116 Transport-associated OB, type 1 LH59_21240 8fe8b89b1755824a33a4434486c46745 264 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 123 190 6.6E-25 T 14-10-2018 IPR004606 Molybdenum-pterin binding GO:0015689 LH59_21240 8fe8b89b1755824a33a4434486c46745 264 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 195 261 3.4E-21 T 14-10-2018 IPR004606 Molybdenum-pterin binding GO:0015689 LH59_21240 8fe8b89b1755824a33a4434486c46745 264 SUPERFAMILY SSF50331 195 262 7.29E-21 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal LH59_08115 5cbbebcc522542f71a2baece6d4b60c9 394 SUPERFAMILY SSF53383 1 389 1.33E-105 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_08115 5cbbebcc522542f71a2baece6d4b60c9 394 Gene3D G3DSA:3.40.640.10 64 287 3.2E-131 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_08115 5cbbebcc522542f71a2baece6d4b60c9 394 Pfam PF00155 Aminotransferase class I and II 31 377 1.8E-55 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LH59_08115 5cbbebcc522542f71a2baece6d4b60c9 394 Gene3D G3DSA:3.90.1150.10 288 385 3.2E-131 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_19045 912b06ea0c86e108ac622783c1d173df 268 SUPERFAMILY SSF52096 1 261 1.71E-78 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily LH59_19045 912b06ea0c86e108ac622783c1d173df 268 Gene3D G3DSA:3.90.226.10 3 264 5.9E-77 T 14-10-2018 LH59_19045 912b06ea0c86e108ac622783c1d173df 268 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 257 8.0E-53 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 LH59_07835 7621cc593f886fbf993d8b35e5853c0b 460 Pfam PF00772 DnaB-like helicase N terminal domain 15 116 4.3E-32 T 14-10-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 LH59_07835 7621cc593f886fbf993d8b35e5853c0b 460 SUPERFAMILY SSF48024 13 124 2.09E-35 T 14-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 LH59_07835 7621cc593f886fbf993d8b35e5853c0b 460 Pfam PF03796 DnaB-like helicase C terminal domain 195 450 3.2E-113 T 14-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 LH59_07835 7621cc593f886fbf993d8b35e5853c0b 460 SMART SM00382 212 410 7.8E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_07835 7621cc593f886fbf993d8b35e5853c0b 460 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 15 451 1.6E-174 T 14-10-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 LH59_07835 7621cc593f886fbf993d8b35e5853c0b 460 SUPERFAMILY SSF52540 193 444 2.25E-53 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_07835 7621cc593f886fbf993d8b35e5853c0b 460 Gene3D G3DSA:1.10.860.10 7 173 5.7E-51 T 14-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal LH59_07835 7621cc593f886fbf993d8b35e5853c0b 460 Gene3D G3DSA:3.40.50.300 174 453 1.5E-101 T 14-10-2018 LH59_23765 8c011b91d287dd1c8f0a9034f472dc9d 202 Pfam PF00043 Glutathione S-transferase, C-terminal domain 123 196 3.5E-9 T 14-10-2018 IPR004046 Glutathione S-transferase, C-terminal LH59_23765 8c011b91d287dd1c8f0a9034f472dc9d 202 SUPERFAMILY SSF52833 2 85 2.84E-20 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_23765 8c011b91d287dd1c8f0a9034f472dc9d 202 Gene3D G3DSA:3.40.30.10 1 86 5.6E-21 T 14-10-2018 LH59_23765 8c011b91d287dd1c8f0a9034f472dc9d 202 Pfam PF02798 Glutathione S-transferase, N-terminal domain 5 73 1.1E-12 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 LH59_23765 8c011b91d287dd1c8f0a9034f472dc9d 202 Gene3D G3DSA:1.20.1050.10 87 202 1.9E-24 T 14-10-2018 LH59_23765 8c011b91d287dd1c8f0a9034f472dc9d 202 SUPERFAMILY SSF47616 82 199 1.53E-23 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily LH59_19710 d8cfd78abc48a73193307b1c470795d0 297 Gene3D G3DSA:3.40.190.10 165 262 2.0E-50 T 14-10-2018 LH59_19710 d8cfd78abc48a73193307b1c470795d0 297 Gene3D G3DSA:1.10.10.10 1 83 5.3E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_19710 d8cfd78abc48a73193307b1c470795d0 297 Gene3D G3DSA:3.40.190.10 89 286 2.0E-50 T 14-10-2018 LH59_19710 d8cfd78abc48a73193307b1c470795d0 297 Pfam PF03466 LysR substrate binding domain 90 288 2.6E-22 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_19710 d8cfd78abc48a73193307b1c470795d0 297 SUPERFAMILY SSF53850 85 288 5.07E-37 T 14-10-2018 LH59_19710 d8cfd78abc48a73193307b1c470795d0 297 SUPERFAMILY SSF46785 1 79 4.14E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_19710 d8cfd78abc48a73193307b1c470795d0 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 3.1E-16 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_18705 195576f4dff832ddd3102a61e337f9fa 324 SUPERFAMILY SSF46689 220 271 2.93E-8 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_18705 195576f4dff832ddd3102a61e337f9fa 324 SUPERFAMILY SSF46689 273 323 1.75E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_18705 195576f4dff832ddd3102a61e337f9fa 324 SMART SM00342 237 320 3.8E-24 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_18705 195576f4dff832ddd3102a61e337f9fa 324 Gene3D G3DSA:1.10.10.60 212 270 2.0E-11 T 14-10-2018 LH59_18705 195576f4dff832ddd3102a61e337f9fa 324 Pfam PF01965 DJ-1/PfpI family 51 182 3.4E-9 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 LH59_18705 195576f4dff832ddd3102a61e337f9fa 324 SUPERFAMILY SSF52317 5 203 1.09E-31 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_18705 195576f4dff832ddd3102a61e337f9fa 324 Gene3D G3DSA:1.10.10.60 271 324 1.1E-14 T 14-10-2018 LH59_18705 195576f4dff832ddd3102a61e337f9fa 324 Pfam PF12833 Helix-turn-helix domain 243 322 1.4E-21 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_18705 195576f4dff832ddd3102a61e337f9fa 324 Gene3D G3DSA:3.40.50.880 5 207 3.0E-37 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_11125 1fe48a755eb7210b7618294e3f8d065b 726 TIGRFAM TIGR03396 PC_PLC: phospholipase C, phosphocholine-specific 12 725 1.3E-289 T 14-10-2018 IPR017767 Bacterial phospholipase C, phosphocholine-specific GO:0034480 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 LH59_11125 1fe48a755eb7210b7618294e3f8d065b 726 Pfam PF05506 Domain of unknown function (DUF756) 529 617 1.7E-24 T 14-10-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 LH59_11125 1fe48a755eb7210b7618294e3f8d065b 726 Pfam PF05506 Domain of unknown function (DUF756) 629 711 3.8E-21 T 14-10-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 LH59_11125 1fe48a755eb7210b7618294e3f8d065b 726 Gene3D G3DSA:3.40.720.10 292 506 1.6E-51 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 LH59_11125 1fe48a755eb7210b7618294e3f8d065b 726 Gene3D G3DSA:3.40.720.10 43 203 3.8E-30 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 LH59_11125 1fe48a755eb7210b7618294e3f8d065b 726 Pfam PF04185 Phosphoesterase family 54 457 1.9E-111 T 14-10-2018 IPR007312 Phosphoesterase GO:0016788 LH59_03700 977bf85732f782275d241bc3fc997eb4 251 Pfam PF00005 ABC transporter 23 178 1.1E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_03700 977bf85732f782275d241bc3fc997eb4 251 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 225 247 2.4E-9 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal LH59_03700 977bf85732f782275d241bc3fc997eb4 251 Gene3D G3DSA:3.40.50.300 2 249 3.3E-59 T 14-10-2018 LH59_03700 977bf85732f782275d241bc3fc997eb4 251 SUPERFAMILY SSF52540 5 247 3.26E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_03700 977bf85732f782275d241bc3fc997eb4 251 SMART SM00382 31 234 1.5E-4 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_06490 2353c7a5fcfbf4e9d7bf869f72e7b8bc 355 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 338 155.072 T 14-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 LH59_06490 2353c7a5fcfbf4e9d7bf869f72e7b8bc 355 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 2 338 1.3E-115 T 14-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 LH59_06490 2353c7a5fcfbf4e9d7bf869f72e7b8bc 355 Pfam PF02504 Fatty acid synthesis protein 2 322 1.1E-107 T 14-10-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 LH59_06490 2353c7a5fcfbf4e9d7bf869f72e7b8bc 355 Gene3D G3DSA:3.40.718.10 1 345 7.0E-129 T 14-10-2018 LH59_06490 2353c7a5fcfbf4e9d7bf869f72e7b8bc 355 SUPERFAMILY SSF53659 2 333 2.47E-106 T 14-10-2018 LH59_06490 2353c7a5fcfbf4e9d7bf869f72e7b8bc 355 PIRSF PIRSF002465 1 338 8.6E-132 T 14-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 LH59_23460 4646ced11455ba6a12e146d00e864d47 190 Gene3D G3DSA:1.10.260.40 1 79 1.9E-18 T 14-10-2018 LH59_23460 4646ced11455ba6a12e146d00e864d47 190 Pfam PF13560 Helix-turn-helix domain 14 69 2.9E-15 T 14-10-2018 LH59_23460 4646ced11455ba6a12e146d00e864d47 190 SUPERFAMILY SSF47413 12 80 4.5E-18 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 LH59_23460 4646ced11455ba6a12e146d00e864d47 190 SUPERFAMILY SSF51182 68 189 1.74E-13 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_23460 4646ced11455ba6a12e146d00e864d47 190 Gene3D G3DSA:2.60.120.10 101 170 1.0E-6 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_23460 4646ced11455ba6a12e146d00e864d47 190 SMART SM00530 18 73 6.3E-16 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LH59_27565 735941e1accad68eb5ff2f083a39efcc 372 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 123 343 6.3E-15 T 14-10-2018 IPR032095 Saccharopine dehydrogenase, C-terminal Reactome: R-HSA-71064 LH59_27565 735941e1accad68eb5ff2f083a39efcc 372 SUPERFAMILY SSF55347 124 360 2.42E-60 T 14-10-2018 LH59_27565 735941e1accad68eb5ff2f083a39efcc 372 SUPERFAMILY SSF51735 6 178 3.55E-22 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_27565 735941e1accad68eb5ff2f083a39efcc 372 Gene3D G3DSA:3.30.360.10 124 311 2.7E-64 T 14-10-2018 LH59_27565 735941e1accad68eb5ff2f083a39efcc 372 Gene3D G3DSA:3.40.50.720 8 344 2.7E-64 T 14-10-2018 LH59_27565 735941e1accad68eb5ff2f083a39efcc 372 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 8 114 1.8E-15 T 14-10-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 LH59_02610 8d2329ad80bc839237a4ca45062218cd 1203 SUPERFAMILY SSF53323 744 945 3.66E-31 T 14-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 LH59_02610 8d2329ad80bc839237a4ca45062218cd 1203 SUPERFAMILY SSF52518 459 645 1.66E-16 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold LH59_02610 8d2329ad80bc839237a4ca45062218cd 1203 SUPERFAMILY SSF52518 30 209 1.38E-20 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold LH59_02610 8d2329ad80bc839237a4ca45062218cd 1203 Gene3D G3DSA:3.40.920.10 741 948 7.1E-18 T 14-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 LH59_02610 8d2329ad80bc839237a4ca45062218cd 1203 Gene3D G3DSA:3.40.50.970 466 644 1.1E-7 T 14-10-2018 LH59_02610 8d2329ad80bc839237a4ca45062218cd 1203 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 479 628 1.3E-8 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 LH59_02610 8d2329ad80bc839237a4ca45062218cd 1203 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 752 939 6.5E-22 T 14-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 LH59_02610 8d2329ad80bc839237a4ca45062218cd 1203 Gene3D G3DSA:3.40.50.970 17 232 1.7E-27 T 14-10-2018 LH59_11590 4a465938359810d20e4d0b2456e01621 323 Gene3D G3DSA:3.40.190.10 127 248 2.5E-112 T 14-10-2018 LH59_11590 4a465938359810d20e4d0b2456e01621 323 Gene3D G3DSA:3.40.190.150 29 313 2.5E-112 T 14-10-2018 LH59_11590 4a465938359810d20e4d0b2456e01621 323 PIRSF PIRSF017082 1 323 1.0E-84 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_11590 4a465938359810d20e4d0b2456e01621 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 319 1.0E-78 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_11590 4a465938359810d20e4d0b2456e01621 323 SUPERFAMILY SSF53850 116 285 7.21E-14 T 14-10-2018 LH59_07065 d14d75d6c6d3828571ce6d8d351a80cc 245 SUPERFAMILY SSF51735 3 244 1.9E-78 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_07065 d14d75d6c6d3828571ce6d8d351a80cc 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 3.0E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_07065 d14d75d6c6d3828571ce6d8d351a80cc 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 3.0E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_07065 d14d75d6c6d3828571ce6d8d351a80cc 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 3.0E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_07065 d14d75d6c6d3828571ce6d8d351a80cc 245 Pfam PF00106 short chain dehydrogenase 4 196 2.4E-62 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_07065 d14d75d6c6d3828571ce6d8d351a80cc 245 Gene3D G3DSA:3.40.50.720 1 245 2.7E-82 T 14-10-2018 LH59_07065 d14d75d6c6d3828571ce6d8d351a80cc 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 188 5.6E-4 T 14-10-2018 LH59_07065 d14d75d6c6d3828571ce6d8d351a80cc 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 6.0E-45 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_07065 d14d75d6c6d3828571ce6d8d351a80cc 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 6.0E-45 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_07065 d14d75d6c6d3828571ce6d8d351a80cc 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 6.0E-45 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_07065 d14d75d6c6d3828571ce6d8d351a80cc 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 6.0E-45 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_07065 d14d75d6c6d3828571ce6d8d351a80cc 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 6.0E-45 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_07065 d14d75d6c6d3828571ce6d8d351a80cc 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 6.0E-45 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_07065 d14d75d6c6d3828571ce6d8d351a80cc 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LH59_07065 d14d75d6c6d3828571ce6d8d351a80cc 245 TIGRFAM TIGR01829 AcAcCoA_reduct: acetoacetyl-CoA reductase 4 244 2.3E-118 T 14-10-2018 IPR011283 Acetoacetyl-CoA reductase GO:0005737|GO:0018454|GO:0042619|GO:0055114 KEGG: 00630+1.1.1.36|KEGG: 00650+1.1.1.36|MetaCyc: PWY-5676|MetaCyc: PWY-5741|MetaCyc: PWY-7216|MetaCyc: PWY-7948 LH59_05160 86760d5d0c69fa356f36278004a3cdd8 270 Pfam PF00994 Probable molybdopterin binding domain 12 177 1.7E-23 T 14-10-2018 IPR001453 MoaB/Mog domain LH59_05160 86760d5d0c69fa356f36278004a3cdd8 270 SMART SM00852 11 184 3.3E-27 T 14-10-2018 IPR001453 MoaB/Mog domain LH59_05160 86760d5d0c69fa356f36278004a3cdd8 270 SUPERFAMILY SSF53218 9 218 1.22E-32 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily LH59_05160 86760d5d0c69fa356f36278004a3cdd8 270 Gene3D G3DSA:3.40.980.10 7 180 9.5E-40 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily LH59_27710 5d6b6053731aca2436575720dd4b2a79 115 Pfam PF03091 CutA1 divalent ion tolerance protein 9 106 7.2E-29 T 14-10-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 LH59_27710 5d6b6053731aca2436575720dd4b2a79 115 Gene3D G3DSA:3.30.70.120 3 115 1.9E-32 T 14-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal LH59_27710 5d6b6053731aca2436575720dd4b2a79 115 SUPERFAMILY SSF54913 5 107 1.15E-33 T 14-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta LH59_17860 f5fcce658a36eca5f5d71653be079804 1273 Pfam PF00171 Aldehyde dehydrogenase family 655 1097 7.8E-118 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 LH59_17860 f5fcce658a36eca5f5d71653be079804 1273 Gene3D G3DSA:1.20.5.550 86 135 9.5E-17 T 14-10-2018 IPR024090 Proline dehydrogenase PutA, domain I GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 LH59_17860 f5fcce658a36eca5f5d71653be079804 1273 Gene3D G3DSA:3.20.20.220 210 599 2.3E-151 T 14-10-2018 LH59_17860 f5fcce658a36eca5f5d71653be079804 1273 Gene3D G3DSA:1.10.1220.10 11 51 1.1E-15 T 14-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 LH59_17860 f5fcce658a36eca5f5d71653be079804 1273 SUPERFAMILY SSF47598 4 45 8.67E-8 T 14-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 LH59_17860 f5fcce658a36eca5f5d71653be079804 1273 SUPERFAMILY SSF81935 87 253 2.22E-62 T 14-10-2018 IPR024089 Proline dehydrogenase PutA, domain I/II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 LH59_17860 f5fcce658a36eca5f5d71653be079804 1273 Gene3D G3DSA:3.40.605.10 641 1101 9.8E-146 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 LH59_17860 f5fcce658a36eca5f5d71653be079804 1273 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 906 917 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 LH59_17860 f5fcce658a36eca5f5d71653be079804 1273 PIRSF PIRSF000197 73 1273 0.0 T 14-10-2018 IPR025703 Bifunctional protein PutA GO:0003700|GO:0003842|GO:0004657|GO:0006355|GO:0010133 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 LH59_17860 f5fcce658a36eca5f5d71653be079804 1273 SUPERFAMILY SSF53720 638 1104 4.45E-128 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 LH59_17860 f5fcce658a36eca5f5d71653be079804 1273 Pfam PF14850 DNA-binding domain of Proline dehydrogenase 141 252 1.1E-46 T 14-10-2018 IPR024082 Proline dehydrogenase PutA, domain II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 LH59_17860 f5fcce658a36eca5f5d71653be079804 1273 Pfam PF01619 Proline dehydrogenase 265 561 7.4E-98 T 14-10-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 LH59_17860 f5fcce658a36eca5f5d71653be079804 1273 SUPERFAMILY SSF51730 255 604 1.65E-120 T 14-10-2018 IPR029041 FAD-linked oxidoreductase-like LH59_17860 f5fcce658a36eca5f5d71653be079804 1273 Gene3D G3DSA:3.40.309.10 881 1073 9.8E-146 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 LH59_17860 f5fcce658a36eca5f5d71653be079804 1273 TIGRFAM TIGR01238 D1pyr5carbox3: delta-1-pyrroline-5-carboxylate dehydrogenase 608 1103 1.2E-232 T 14-10-2018 IPR005933 Delta-1-pyrroline-5-carboxylate dehydrogenase 3 GO:0003842|GO:0006561|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 LH59_16795 af3ac133fc9b44f0d45db9d708f2d797 92 Pfam PF05015 RelE-like toxin of type II toxin-antitoxin system HigB 4 92 8.6E-26 T 14-10-2018 IPR007711 Toxin HigB-1 LH59_16795 af3ac133fc9b44f0d45db9d708f2d797 92 SUPERFAMILY SSF143011 1 92 4.71E-15 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily LH59_16795 af3ac133fc9b44f0d45db9d708f2d797 92 Gene3D G3DSA:3.30.2310.20 1 92 2.8E-35 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily LH59_00185 e7c195c1b71d4565789ea908c5870a32 351 SUPERFAMILY SSF52540 4 240 1.01E-86 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_00185 e7c195c1b71d4565789ea908c5870a32 351 Pfam PF00005 ABC transporter 20 161 6.6E-36 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_00185 e7c195c1b71d4565789ea908c5870a32 351 Pfam PF08402 TOBE domain 272 342 1.6E-11 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 LH59_00185 e7c195c1b71d4565789ea908c5870a32 351 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_00185 e7c195c1b71d4565789ea908c5870a32 351 SMART SM00382 28 211 2.6E-20 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_00185 e7c195c1b71d4565789ea908c5870a32 351 Gene3D G3DSA:3.40.50.300 2 237 1.0E-77 T 14-10-2018 LH59_00185 e7c195c1b71d4565789ea908c5870a32 351 SUPERFAMILY SSF50331 269 342 2.21E-8 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal LH59_18620 20f79288f4ff66c66a4adb5c6d776014 571 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 38 46 - T 14-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 LH59_18620 20f79288f4ff66c66a4adb5c6d776014 571 Pfam PF00175 Oxidoreductase NAD-binding domain 214 314 1.3E-12 T 14-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 LH59_18620 20f79288f4ff66c66a4adb5c6d776014 571 Gene3D G3DSA:3.90.230.10 359 529 8.1E-23 T 14-10-2018 LH59_18620 20f79288f4ff66c66a4adb5c6d776014 571 Pfam PF00970 Oxidoreductase FAD-binding domain 111 198 6.6E-7 T 14-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 LH59_18620 20f79288f4ff66c66a4adb5c6d776014 571 SUPERFAMILY SSF63380 103 198 1.54E-18 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel LH59_18620 20f79288f4ff66c66a4adb5c6d776014 571 SUPERFAMILY SSF54292 11 88 2.88E-16 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 LH59_18620 20f79288f4ff66c66a4adb5c6d776014 571 Pfam PF00557 Metallopeptidase family M24 363 517 4.1E-22 T 14-10-2018 IPR000994 Peptidase M24 LH59_18620 20f79288f4ff66c66a4adb5c6d776014 571 Gene3D G3DSA:3.40.50.80 206 337 1.5E-21 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain LH59_18620 20f79288f4ff66c66a4adb5c6d776014 571 SUPERFAMILY SSF55920 361 526 4.58E-28 T 14-10-2018 IPR036005 Creatinase/aminopeptidase-like LH59_18620 20f79288f4ff66c66a4adb5c6d776014 571 Gene3D G3DSA:2.40.30.10 105 199 2.8E-19 T 14-10-2018 LH59_18620 20f79288f4ff66c66a4adb5c6d776014 571 SUPERFAMILY SSF52343 210 334 6.81E-27 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain LH59_18620 20f79288f4ff66c66a4adb5c6d776014 571 Gene3D G3DSA:3.10.20.30 3 92 8.3E-16 T 14-10-2018 IPR012675 Beta-grasp domain superfamily LH59_18620 20f79288f4ff66c66a4adb5c6d776014 571 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 17 81 1.1E-10 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 LH59_18620 20f79288f4ff66c66a4adb5c6d776014 571 PRINTS PR00410 Phenol hydroxylase reductase family signature 131 143 1.3E-8 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 LH59_18620 20f79288f4ff66c66a4adb5c6d776014 571 PRINTS PR00410 Phenol hydroxylase reductase family signature 147 154 1.3E-8 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 LH59_18620 20f79288f4ff66c66a4adb5c6d776014 571 PRINTS PR00410 Phenol hydroxylase reductase family signature 300 308 1.3E-8 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 LH59_18620 20f79288f4ff66c66a4adb5c6d776014 571 PRINTS PR00410 Phenol hydroxylase reductase family signature 238 247 1.3E-8 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 LH59_18620 20f79288f4ff66c66a4adb5c6d776014 571 PRINTS PR00410 Phenol hydroxylase reductase family signature 213 232 1.3E-8 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 LH59_16140 8d05b70b27ac33db9ec63526c853bf29 331 SUPERFAMILY SSF53850 120 291 2.29E-14 T 14-10-2018 LH59_16140 8d05b70b27ac33db9ec63526c853bf29 331 Gene3D G3DSA:3.40.190.10 133 256 1.3E-110 T 14-10-2018 LH59_16140 8d05b70b27ac33db9ec63526c853bf29 331 PIRSF PIRSF017082 5 331 1.7E-87 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_16140 8d05b70b27ac33db9ec63526c853bf29 331 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 56 327 9.1E-87 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_16140 8d05b70b27ac33db9ec63526c853bf29 331 Gene3D G3DSA:3.40.190.150 36 321 1.3E-110 T 14-10-2018 LH59_15860 4efcc7658504e3349cfb53925ffb99c5 144 SUPERFAMILY SSF54427 9 138 3.68E-30 T 14-10-2018 IPR032710 NTF2-like domain superfamily LH59_15860 4efcc7658504e3349cfb53925ffb99c5 144 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 14 127 2.7E-15 T 14-10-2018 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 LH59_15860 4efcc7658504e3349cfb53925ffb99c5 144 Gene3D G3DSA:3.10.450.50 7 137 7.0E-29 T 14-10-2018 LH59_15860 4efcc7658504e3349cfb53925ffb99c5 144 Pfam PF14534 Domain of unknown function (DUF4440) 13 120 2.5E-11 T 14-10-2018 IPR027843 Domain of unknown function DUF4440 LH59_10155 d789246f6043beb410d180ad43827f9b 761 SUPERFAMILY SSF81442 276 750 1.31E-82 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_10155 d789246f6043beb410d180ad43827f9b 761 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 282 726 2.7E-71 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_10155 d789246f6043beb410d180ad43827f9b 761 Gene3D G3DSA:1.20.210.10 222 751 3.0E-168 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_19935 d87b56b0040cdbeb26d0761eab1e26a1 557 Gene3D G3DSA:3.40.50.10490 44 494 2.0E-154 T 14-10-2018 LH59_19935 d87b56b0040cdbeb26d0761eab1e26a1 557 Gene3D G3DSA:3.40.50.10490 99 280 2.0E-154 T 14-10-2018 LH59_19935 d87b56b0040cdbeb26d0761eab1e26a1 557 SUPERFAMILY SSF53697 43 540 1.13E-142 T 14-10-2018 LH59_19935 d87b56b0040cdbeb26d0761eab1e26a1 557 Pfam PF00342 Phosphoglucose isomerase 65 530 3.5E-133 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_19935 d87b56b0040cdbeb26d0761eab1e26a1 557 Gene3D G3DSA:1.10.1390.10 495 541 8.7E-15 T 14-10-2018 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_19935 d87b56b0040cdbeb26d0761eab1e26a1 557 PRINTS PR00662 Glucose-6-phosphate isomerase signature 141 160 4.0E-41 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_19935 d87b56b0040cdbeb26d0761eab1e26a1 557 PRINTS PR00662 Glucose-6-phosphate isomerase signature 453 471 4.0E-41 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_19935 d87b56b0040cdbeb26d0761eab1e26a1 557 PRINTS PR00662 Glucose-6-phosphate isomerase signature 485 498 4.0E-41 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_19935 d87b56b0040cdbeb26d0761eab1e26a1 557 PRINTS PR00662 Glucose-6-phosphate isomerase signature 250 268 4.0E-41 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_19935 d87b56b0040cdbeb26d0761eab1e26a1 557 PRINTS PR00662 Glucose-6-phosphate isomerase signature 327 348 4.0E-41 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_19935 d87b56b0040cdbeb26d0761eab1e26a1 557 PRINTS PR00662 Glucose-6-phosphate isomerase signature 471 485 4.0E-41 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_19935 d87b56b0040cdbeb26d0761eab1e26a1 557 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 485 502 - T 14-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_19935 d87b56b0040cdbeb26d0761eab1e26a1 557 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 47 512 32.09 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_04630 0ed68ebe26a645ead04ac04513b3e58b 585 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 53 577 5.1E-126 T 14-10-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-4061|MetaCyc: PWY-5826|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7559 LH59_04630 0ed68ebe26a645ead04ac04513b3e58b 585 Gene3D G3DSA:1.10.246.130 283 400 5.4E-41 T 14-10-2018 LH59_04630 0ed68ebe26a645ead04ac04513b3e58b 585 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 267 283 5.0E-68 T 14-10-2018 LH59_04630 0ed68ebe26a645ead04ac04513b3e58b 585 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 405 423 5.0E-68 T 14-10-2018 LH59_04630 0ed68ebe26a645ead04ac04513b3e58b 585 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 427 445 5.0E-68 T 14-10-2018 LH59_04630 0ed68ebe26a645ead04ac04513b3e58b 585 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 149 167 5.0E-68 T 14-10-2018 LH59_04630 0ed68ebe26a645ead04ac04513b3e58b 585 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 74 99 5.0E-68 T 14-10-2018 LH59_04630 0ed68ebe26a645ead04ac04513b3e58b 585 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 167 186 5.0E-68 T 14-10-2018 LH59_04630 0ed68ebe26a645ead04ac04513b3e58b 585 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 464 479 5.0E-68 T 14-10-2018 LH59_04630 0ed68ebe26a645ead04ac04513b3e58b 585 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 297 316 5.0E-68 T 14-10-2018 LH59_04630 0ed68ebe26a645ead04ac04513b3e58b 585 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 488 505 5.0E-68 T 14-10-2018 LH59_04630 0ed68ebe26a645ead04ac04513b3e58b 585 SUPERFAMILY SSF56235 44 584 1.04E-168 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal LH59_04630 0ed68ebe26a645ead04ac04513b3e58b 585 Pfam PF01019 Gamma-glutamyltranspeptidase 67 580 2.1E-153 T 14-10-2018 LH59_04630 0ed68ebe26a645ead04ac04513b3e58b 585 Gene3D G3DSA:3.60.20.40 405 585 1.8E-55 T 14-10-2018 LH59_12345 d908c5ad229b5293c830e56f91558149 343 SUPERFAMILY SSF53067 102 312 3.24E-45 T 14-10-2018 LH59_12345 d908c5ad229b5293c830e56f91558149 343 Gene3D G3DSA:3.30.420.40 129 297 6.7E-123 T 14-10-2018 LH59_12345 d908c5ad229b5293c830e56f91558149 343 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 1 339 61.691 T 14-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 LH59_12345 d908c5ad229b5293c830e56f91558149 343 Gene3D G3DSA:3.30.420.40 3 319 6.7E-123 T 14-10-2018 LH59_12345 d908c5ad229b5293c830e56f91558149 343 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 310 6.9E-112 T 14-10-2018 IPR017861 Kae1/TsaD family LH59_12345 d908c5ad229b5293c830e56f91558149 343 SUPERFAMILY SSF53067 2 122 8.74E-27 T 14-10-2018 LH59_12345 d908c5ad229b5293c830e56f91558149 343 Pfam PF00814 Glycoprotease family 24 311 1.9E-97 T 14-10-2018 IPR000905 Gcp-like domain LH59_12345 d908c5ad229b5293c830e56f91558149 343 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 3 317 1.8E-130 T 14-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 LH59_12345 d908c5ad229b5293c830e56f91558149 343 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 97 116 3.6E-48 T 14-10-2018 IPR017861 Kae1/TsaD family LH59_12345 d908c5ad229b5293c830e56f91558149 343 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 3.6E-48 T 14-10-2018 IPR017861 Kae1/TsaD family LH59_12345 d908c5ad229b5293c830e56f91558149 343 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 131 143 3.6E-48 T 14-10-2018 IPR017861 Kae1/TsaD family LH59_12345 d908c5ad229b5293c830e56f91558149 343 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 267 276 3.6E-48 T 14-10-2018 IPR017861 Kae1/TsaD family LH59_12345 d908c5ad229b5293c830e56f91558149 343 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 76 96 3.6E-48 T 14-10-2018 IPR017861 Kae1/TsaD family LH59_12345 d908c5ad229b5293c830e56f91558149 343 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 154 175 3.6E-48 T 14-10-2018 IPR017861 Kae1/TsaD family LH59_05580 7a79d45011df2cdb4ab897358bd2b653 326 Gene3D G3DSA:3.40.50.12260 195 298 1.3E-75 T 14-10-2018 LH59_05580 7a79d45011df2cdb4ab897358bd2b653 326 Gene3D G3DSA:3.40.50.12250 46 305 1.3E-75 T 14-10-2018 LH59_05580 7a79d45011df2cdb4ab897358bd2b653 326 SUPERFAMILY SSF53807 42 311 6.67E-61 T 14-10-2018 LH59_05580 7a79d45011df2cdb4ab897358bd2b653 326 Pfam PF01497 Periplasmic binding protein 62 301 1.5E-31 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain LH59_17375 7da82c02eea1d208fbebab57dca2567b 129 Gene3D G3DSA:1.20.1270.180 29 129 4.0E-11 T 14-10-2018 LH59_17375 7da82c02eea1d208fbebab57dca2567b 129 Pfam PF07007 Lysozyme inhibitor LprI 44 123 7.3E-12 T 14-10-2018 IPR009739 Lysozyme inhibitor LprI, N-terminal LH59_11385 1ab28269a1359a04ec85067cd903683c 97 TIGRFAM TIGR03824 FlgM_jcvi: flagellar biosynthesis anti-sigma factor FlgM 2 92 1.6E-17 T 14-10-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 LH59_11385 1ab28269a1359a04ec85067cd903683c 97 Pfam PF04316 Anti-sigma-28 factor, FlgM 40 89 2.3E-12 T 14-10-2018 IPR031316 Anti-sigma-28 factor FlgM, C-terminal LH59_11385 1ab28269a1359a04ec85067cd903683c 97 SUPERFAMILY SSF101498 23 91 4.32E-12 T 14-10-2018 IPR035890 Anti-sigma-28 factor FlgM superfamily LH59_18525 b5aff514d08605258e3fccd232f46c45 505 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 72 238 1.9E-35 T 14-10-2018 IPR000160 GGDEF domain LH59_18525 b5aff514d08605258e3fccd232f46c45 505 Gene3D G3DSA:3.30.450.20 1 64 2.9E-10 T 14-10-2018 LH59_18525 b5aff514d08605258e3fccd232f46c45 505 Gene3D G3DSA:3.20.20.450 251 503 1.4E-90 T 14-10-2018 IPR035919 EAL domain superfamily LH59_18525 b5aff514d08605258e3fccd232f46c45 505 SUPERFAMILY SSF55073 81 241 2.98E-45 T 14-10-2018 IPR029787 Nucleotide cyclase LH59_18525 b5aff514d08605258e3fccd232f46c45 505 Pfam PF00563 EAL domain 257 490 5.8E-66 T 14-10-2018 IPR001633 EAL domain LH59_18525 b5aff514d08605258e3fccd232f46c45 505 Gene3D G3DSA:3.30.70.270 70 244 1.2E-53 T 14-10-2018 LH59_18525 b5aff514d08605258e3fccd232f46c45 505 SUPERFAMILY SSF141868 256 503 2.22E-79 T 14-10-2018 IPR035919 EAL domain superfamily LH59_18525 b5aff514d08605258e3fccd232f46c45 505 Pfam PF00990 Diguanylate cyclase, GGDEF domain 76 234 2.7E-42 T 14-10-2018 IPR000160 GGDEF domain LH59_18525 b5aff514d08605258e3fccd232f46c45 505 SMART SM00052 250 496 2.5E-100 T 14-10-2018 IPR001633 EAL domain LH59_18525 b5aff514d08605258e3fccd232f46c45 505 SMART SM00267 65 240 2.4E-59 T 14-10-2018 IPR000160 GGDEF domain LH59_21440 6bbeca830910bd2b6e6b47a8aa879014 421 Pfam PF02353 Mycolic acid cyclopropane synthetase 107 384 1.3E-94 T 14-10-2018 LH59_21440 6bbeca830910bd2b6e6b47a8aa879014 421 SUPERFAMILY SSF53335 118 389 2.48E-74 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_21440 6bbeca830910bd2b6e6b47a8aa879014 421 PIRSF PIRSF003085 1 413 1.4E-130 T 14-10-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 LH59_21440 6bbeca830910bd2b6e6b47a8aa879014 421 Gene3D G3DSA:3.40.50.150 115 392 5.2E-95 T 14-10-2018 LH59_03085 8183b0a11a81359587af0a287361744c 233 SUPERFAMILY SSF161098 18 213 1.96E-40 T 14-10-2018 IPR035906 MetI-like superfamily LH59_03085 8183b0a11a81359587af0a287361744c 233 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 19 122 1.7E-16 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 LH59_03085 8183b0a11a81359587af0a287361744c 233 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 39 228 2.5E-17 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_03085 8183b0a11a81359587af0a287361744c 233 Gene3D G3DSA:1.10.3720.10 5 229 6.7E-49 T 14-10-2018 IPR035906 MetI-like superfamily LH59_19275 4d2d4bb3a02b0f1d9bbcaf6be9b12777 280 Gene3D G3DSA:3.10.310.10 124 270 1.3E-73 T 14-10-2018 LH59_19275 4d2d4bb3a02b0f1d9bbcaf6be9b12777 280 PIRSF PIRSF016184 1 279 5.8E-62 T 14-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 LH59_19275 4d2d4bb3a02b0f1d9bbcaf6be9b12777 280 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 4 263 2.7E-45 T 14-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 LH59_19275 4d2d4bb3a02b0f1d9bbcaf6be9b12777 280 Pfam PF02567 Phenazine biosynthesis-like protein 8 275 1.9E-48 T 14-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 LH59_19275 4d2d4bb3a02b0f1d9bbcaf6be9b12777 280 SUPERFAMILY SSF54506 1 277 9.42E-63 T 14-10-2018 LH59_19275 4d2d4bb3a02b0f1d9bbcaf6be9b12777 280 Gene3D G3DSA:3.10.310.10 6 123 1.3E-73 T 14-10-2018 LH59_05925 cc39b9f475129990160f69418bf3bf96 226 Gene3D G3DSA:1.20.120.520 73 221 2.3E-28 T 14-10-2018 LH59_05925 cc39b9f475129990160f69418bf3bf96 226 Pfam PF01814 Hemerythrin HHE cation binding domain 77 215 1.5E-22 T 14-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 LH59_05925 cc39b9f475129990160f69418bf3bf96 226 TIGRFAM TIGR03652 FeS_repair_RIC: iron-sulfur cluster repair di-iron protein 8 216 1.9E-77 T 14-10-2018 IPR019903 Repair of iron centres family LH59_05925 cc39b9f475129990160f69418bf3bf96 226 Pfam PF04405 Domain of Unknown function (DUF542) 5 58 1.5E-20 T 14-10-2018 IPR019903 Repair of iron centres family LH59_00970 f1f3ec69d3054a33d176c65cceee7f20 224 Pfam PF01634 ATP phosphoribosyltransferase 58 214 7.5E-49 T 14-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 LH59_00970 f1f3ec69d3054a33d176c65cceee7f20 224 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 156 177 - T 14-10-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 LH59_00970 f1f3ec69d3054a33d176c65cceee7f20 224 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 8 221 55.171 T 14-10-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 LH59_00970 f1f3ec69d3054a33d176c65cceee7f20 224 Gene3D G3DSA:3.40.190.10 10 210 2.4E-70 T 14-10-2018 LH59_00970 f1f3ec69d3054a33d176c65cceee7f20 224 Gene3D G3DSA:3.40.190.10 103 189 2.4E-70 T 14-10-2018 LH59_00970 f1f3ec69d3054a33d176c65cceee7f20 224 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 9 197 7.0E-60 T 14-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 LH59_00970 f1f3ec69d3054a33d176c65cceee7f20 224 SUPERFAMILY SSF53850 8 218 2.15E-65 T 14-10-2018 LH59_11260 1c5f0a64209bc8aea1bbd26e5a4d7abf 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 1.2E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_11260 1c5f0a64209bc8aea1bbd26e5a4d7abf 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 1.2E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_11260 1c5f0a64209bc8aea1bbd26e5a4d7abf 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 1.2E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_11260 1c5f0a64209bc8aea1bbd26e5a4d7abf 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 1.2E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_11260 1c5f0a64209bc8aea1bbd26e5a4d7abf 257 Gene3D G3DSA:3.40.50.720 1 257 1.6E-65 T 14-10-2018 LH59_11260 1c5f0a64209bc8aea1bbd26e5a4d7abf 257 SUPERFAMILY SSF51735 5 256 3.21E-49 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_11260 1c5f0a64209bc8aea1bbd26e5a4d7abf 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 255 4.5E-39 T 14-10-2018 LH59_19735 88da9c6948995de9e387ac0ab8578118 296 SUPERFAMILY SSF46785 7 115 1.43E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_19735 88da9c6948995de9e387ac0ab8578118 296 SUPERFAMILY SSF53850 94 293 8.14E-34 T 14-10-2018 LH59_19735 88da9c6948995de9e387ac0ab8578118 296 Gene3D G3DSA:1.10.10.10 7 93 4.8E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_19735 88da9c6948995de9e387ac0ab8578118 296 Pfam PF03466 LysR substrate binding domain 93 293 1.0E-28 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_19735 88da9c6948995de9e387ac0ab8578118 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 3.6E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_19735 88da9c6948995de9e387ac0ab8578118 296 Gene3D G3DSA:3.40.190.290 95 294 8.8E-44 T 14-10-2018 LH59_18820 bf2ecf2070d0fde4b76e7f68e6f29bb7 186 SMART SM00421 122 179 2.7E-20 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_18820 bf2ecf2070d0fde4b76e7f68e6f29bb7 186 Gene3D G3DSA:1.10.10.10 120 180 1.2E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_18820 bf2ecf2070d0fde4b76e7f68e6f29bb7 186 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 11 95 2.0E-9 T 14-10-2018 IPR000014 PAS domain LH59_18820 bf2ecf2070d0fde4b76e7f68e6f29bb7 186 SMART SM00091 5 71 9.7E-4 T 14-10-2018 IPR000014 PAS domain LH59_18820 bf2ecf2070d0fde4b76e7f68e6f29bb7 186 Gene3D G3DSA:3.30.450.20 9 118 1.3E-16 T 14-10-2018 LH59_18820 bf2ecf2070d0fde4b76e7f68e6f29bb7 186 Pfam PF00196 Bacterial regulatory proteins, luxR family 124 177 3.4E-20 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_18820 bf2ecf2070d0fde4b76e7f68e6f29bb7 186 SUPERFAMILY SSF46894 106 180 4.08E-21 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LH59_18820 bf2ecf2070d0fde4b76e7f68e6f29bb7 186 Pfam PF13426 PAS domain 25 99 3.7E-8 T 14-10-2018 IPR000014 PAS domain LH59_18820 bf2ecf2070d0fde4b76e7f68e6f29bb7 186 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 167 2.2E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_18820 bf2ecf2070d0fde4b76e7f68e6f29bb7 186 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 139 155 2.2E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_18820 bf2ecf2070d0fde4b76e7f68e6f29bb7 186 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 125 139 2.2E-12 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_18820 bf2ecf2070d0fde4b76e7f68e6f29bb7 186 SUPERFAMILY SSF55785 23 110 6.81E-12 T 14-10-2018 IPR035965 PAS domain superfamily LH59_02865 0e48902dd3f305adfbf3db185f976713 288 Gene3D G3DSA:3.40.50.300 56 197 1.4E-11 T 14-10-2018 LH59_02865 0e48902dd3f305adfbf3db185f976713 288 Pfam PF05673 Protein of unknown function (DUF815) 35 286 3.5E-105 T 14-10-2018 IPR008533 Domain of unknown function DUF815 LH59_02865 0e48902dd3f305adfbf3db185f976713 288 SUPERFAMILY SSF52540 30 194 3.29E-26 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_22055 ea10442835ac98b86dec7f41b72f4ad8 202 SUPERFAMILY SSF111304 8 201 1.57E-67 T 14-10-2018 IPR023627 Recombination protein RecR LH59_22055 ea10442835ac98b86dec7f41b72f4ad8 202 Pfam PF02132 RecR protein 44 82 9.9E-13 T 14-10-2018 IPR023628 Recombination protein RecR, C4-type zinc finger LH59_22055 ea10442835ac98b86dec7f41b72f4ad8 202 TIGRFAM TIGR00615 recR: recombination protein RecR 8 200 2.9E-64 T 14-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 LH59_22055 ea10442835ac98b86dec7f41b72f4ad8 202 Gene3D G3DSA:3.40.1360.10 81 202 6.3E-38 T 14-10-2018 LH59_22055 ea10442835ac98b86dec7f41b72f4ad8 202 Pfam PF13662 Toprim domain 85 175 5.4E-21 T 14-10-2018 IPR006171 TOPRIM domain LH59_22055 ea10442835ac98b86dec7f41b72f4ad8 202 Hamap MF_00017 Recombination protein RecR [recR]. 1 202 87.795 T 14-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 LH59_22055 ea10442835ac98b86dec7f41b72f4ad8 202 Gene3D G3DSA:1.10.8.420 6 57 7.2E-16 T 14-10-2018 LH59_22055 ea10442835ac98b86dec7f41b72f4ad8 202 SMART SM00493 84 169 4.4E-8 T 14-10-2018 IPR006171 TOPRIM domain LH59_27375 08f45626809fe33e3b3088ef12cb65ff 380 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 9 373 1.7E-117 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase LH59_27375 08f45626809fe33e3b3088ef12cb65ff 380 SUPERFAMILY SSF53383 2 378 2.34E-111 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_27375 08f45626809fe33e3b3088ef12cb65ff 380 Gene3D G3DSA:3.40.640.10 1 250 9.2E-100 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_27375 08f45626809fe33e3b3088ef12cb65ff 380 Gene3D G3DSA:3.90.1150.10 252 380 5.4E-25 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_27375 08f45626809fe33e3b3088ef12cb65ff 380 PIRSF PIRSF000390 1 380 3.4E-117 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase LH59_01405 f4ae0c49219bbf3fb66dc565090f455d 446 Gene3D G3DSA:1.10.287.130 172 289 1.0E-20 T 14-10-2018 LH59_01405 f4ae0c49219bbf3fb66dc565090f455d 446 SMART SM00304 168 221 6.7E-5 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_01405 f4ae0c49219bbf3fb66dc565090f455d 446 Gene3D G3DSA:3.30.565.10 295 439 3.8E-24 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_01405 f4ae0c49219bbf3fb66dc565090f455d 446 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 332 429 6.6E-13 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_01405 f4ae0c49219bbf3fb66dc565090f455d 446 TIGRFAM TIGR01386 cztS_silS_copS: heavy metal sensor kinase 6 434 1.3E-102 T 14-10-2018 IPR006290 Heavy metal sensor kinase GO:0000160|GO:0004673|GO:0016020 LH59_01405 f4ae0c49219bbf3fb66dc565090f455d 446 Pfam PF00512 His Kinase A (phospho-acceptor) domain 224 288 5.0E-14 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_01405 f4ae0c49219bbf3fb66dc565090f455d 446 SUPERFAMILY SSF47384 205 288 3.53E-17 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 LH59_01405 f4ae0c49219bbf3fb66dc565090f455d 446 SMART SM00387 331 440 1.1E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_01405 f4ae0c49219bbf3fb66dc565090f455d 446 SUPERFAMILY SSF55874 277 430 1.83E-27 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_01405 f4ae0c49219bbf3fb66dc565090f455d 446 SMART SM00388 222 288 1.8E-17 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_12950 a4274cd09811d11e5fc30ec719583429 255 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 232 253 4.7E-10 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal LH59_12950 a4274cd09811d11e5fc30ec719583429 255 Pfam PF00005 ABC transporter 22 181 1.6E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_12950 a4274cd09811d11e5fc30ec719583429 255 SMART SM00382 30 231 2.4E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_12950 a4274cd09811d11e5fc30ec719583429 255 Gene3D G3DSA:3.40.50.300 3 254 1.1E-63 T 14-10-2018 LH59_12950 a4274cd09811d11e5fc30ec719583429 255 SUPERFAMILY SSF52540 5 253 8.54E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_14165 df663aa96593fbab9800c38e212ba133 380 PIRSF PIRSF000429 1 366 1.5E-18 T 14-10-2018 IPR002155 Thiolase GO:0016747 LH59_14165 df663aa96593fbab9800c38e212ba133 380 SUPERFAMILY SSF53901 244 362 1.0E-16 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_14165 df663aa96593fbab9800c38e212ba133 380 SUPERFAMILY SSF53901 7 219 9.95E-18 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_14165 df663aa96593fbab9800c38e212ba133 380 Gene3D G3DSA:3.40.47.10 2 371 1.0E-71 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_16765 55aeb4949dfb5009360056a5fba82131 484 SUPERFAMILY SSF53720 7 479 3.93E-153 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 LH59_16765 55aeb4949dfb5009360056a5fba82131 484 Pfam PF00171 Aldehyde dehydrogenase family 18 477 2.7E-148 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 LH59_16765 55aeb4949dfb5009360056a5fba82131 484 Gene3D G3DSA:3.40.309.10 260 449 1.4E-156 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 LH59_16765 55aeb4949dfb5009360056a5fba82131 484 Gene3D G3DSA:3.40.605.10 25 476 1.4E-156 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 LH59_08720 5fc28144d3184300290a8162b0332421 299 SUPERFAMILY SSF51197 100 225 1.37E-17 T 14-10-2018 LH59_08720 5fc28144d3184300290a8162b0332421 299 Pfam PF05118 Aspartyl/Asparaginyl beta-hydroxylase 69 222 9.0E-51 T 14-10-2018 IPR007803 Aspartyl/asparaginy/proline hydroxylase GO:0018193 LH59_08720 5fc28144d3184300290a8162b0332421 299 Gene3D G3DSA:2.60.120.330 45 225 3.3E-42 T 14-10-2018 IPR027443 Isopenicillin N synthase-like LH59_26270 351d41f479235a6953006e7c6da302c8 287 Gene3D G3DSA:3.40.710.10 13 283 2.0E-61 T 14-10-2018 LH59_26270 351d41f479235a6953006e7c6da302c8 287 SUPERFAMILY SSF56601 18 253 2.98E-43 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like LH59_26270 351d41f479235a6953006e7c6da302c8 287 Pfam PF13354 Beta-lactamase enzyme family 40 246 1.7E-52 T 14-10-2018 LH59_11755 11be76c630aaf42c65b5d06abdcd2937 308 Pfam PF01145 SPFH domain / Band 7 family 26 195 9.4E-31 T 14-10-2018 IPR001107 Band 7 domain LH59_11755 11be76c630aaf42c65b5d06abdcd2937 308 Pfam PF16200 C-terminal region of band_7 246 305 1.4E-28 T 14-10-2018 IPR032435 Band 7, C-terminal extension Reactome: R-HSA-8949664 LH59_11755 11be76c630aaf42c65b5d06abdcd2937 308 PRINTS PR00721 Stomatin signature 156 174 5.0E-32 T 14-10-2018 IPR001972 Stomatin family GO:0016020 LH59_11755 11be76c630aaf42c65b5d06abdcd2937 308 PRINTS PR00721 Stomatin signature 77 98 5.0E-32 T 14-10-2018 IPR001972 Stomatin family GO:0016020 LH59_11755 11be76c630aaf42c65b5d06abdcd2937 308 PRINTS PR00721 Stomatin signature 112 129 5.0E-32 T 14-10-2018 IPR001972 Stomatin family GO:0016020 LH59_11755 11be76c630aaf42c65b5d06abdcd2937 308 PRINTS PR00721 Stomatin signature 132 155 5.0E-32 T 14-10-2018 IPR001972 Stomatin family GO:0016020 LH59_11755 11be76c630aaf42c65b5d06abdcd2937 308 PRINTS PR00721 Stomatin signature 175 196 5.0E-32 T 14-10-2018 IPR001972 Stomatin family GO:0016020 LH59_11755 11be76c630aaf42c65b5d06abdcd2937 308 PRINTS PR00721 Stomatin signature 29 51 5.0E-32 T 14-10-2018 IPR001972 Stomatin family GO:0016020 LH59_11755 11be76c630aaf42c65b5d06abdcd2937 308 SUPERFAMILY SSF117892 53 187 3.4E-41 T 14-10-2018 IPR036013 Band 7/SPFH domain superfamily LH59_11755 11be76c630aaf42c65b5d06abdcd2937 308 Gene3D G3DSA:3.30.479.30 50 182 1.9E-41 T 14-10-2018 LH59_11755 11be76c630aaf42c65b5d06abdcd2937 308 SMART SM00244 22 180 1.6E-57 T 14-10-2018 IPR001107 Band 7 domain LH59_15815 c623916903d4e55ca8af6a002a9ca85a 518 SUPERFAMILY SSF81296 136 263 5.04E-30 T 14-10-2018 IPR014756 Immunoglobulin E-set LH59_15815 c623916903d4e55ca8af6a002a9ca85a 518 Gene3D G3DSA:3.40.50.1820 259 513 8.5E-65 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_15815 c623916903d4e55ca8af6a002a9ca85a 518 Pfam PF11806 Domain of unknown function (DUF3327) 162 268 2.3E-21 T 14-10-2018 IPR021764 Enterochelin esterase, N-terminal GO:0005506|GO:0005737|GO:0006826|GO:0008849 LH59_15815 c623916903d4e55ca8af6a002a9ca85a 518 Pfam PF00756 Putative esterase 287 510 2.4E-24 T 14-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 LH59_15815 c623916903d4e55ca8af6a002a9ca85a 518 Gene3D G3DSA:2.60.40.10 133 252 6.6E-13 T 14-10-2018 IPR013783 Immunoglobulin-like fold LH59_15815 c623916903d4e55ca8af6a002a9ca85a 518 SUPERFAMILY SSF53474 268 507 1.49E-43 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_27185 9cf498005c77fe9e50a48cb9fd05a68d 154 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 117 141 - T 14-10-2018 IPR020458 Zinc finger, DksA/TraR C4-type conserved site LH59_27185 9cf498005c77fe9e50a48cb9fd05a68d 154 SUPERFAMILY SSF57716 114 152 1.85E-8 T 14-10-2018 LH59_27185 9cf498005c77fe9e50a48cb9fd05a68d 154 Hamap MF_00926 RNA polymerase-binding transcription factor DksA [dksA]. 32 153 28.459 T 14-10-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 LH59_27185 9cf498005c77fe9e50a48cb9fd05a68d 154 Gene3D G3DSA:1.20.120.910 21 152 9.4E-38 T 14-10-2018 LH59_27185 9cf498005c77fe9e50a48cb9fd05a68d 154 SUPERFAMILY SSF109635 20 113 1.44E-28 T 14-10-2018 IPR037187 DksA, N-terminal domain superfamily LH59_27185 9cf498005c77fe9e50a48cb9fd05a68d 154 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 112 146 7.6E-11 T 14-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 LH59_27185 9cf498005c77fe9e50a48cb9fd05a68d 154 TIGRFAM TIGR02420 dksA: RNA polymerase-binding protein DksA 36 144 7.3E-43 T 14-10-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 LH59_00925 deca6aca880fb6cf14e3e13259a15617 122 Pfam PF11969 Scavenger mRNA decapping enzyme C-term binding 4 109 2.2E-24 T 14-10-2018 LH59_00925 deca6aca880fb6cf14e3e13259a15617 122 SUPERFAMILY SSF54197 2 113 3.12E-39 T 14-10-2018 IPR036265 HIT-like superfamily LH59_00925 deca6aca880fb6cf14e3e13259a15617 122 ProSitePatterns PS00892 HIT domain signature. 91 109 - T 14-10-2018 IPR019808 Histidine triad, conserved site LH59_00925 deca6aca880fb6cf14e3e13259a15617 122 PRINTS PR00332 Histidine triad family signature 6 22 2.5E-18 T 14-10-2018 IPR001310 Histidine triad (HIT) protein LH59_00925 deca6aca880fb6cf14e3e13259a15617 122 PRINTS PR00332 Histidine triad family signature 98 108 2.5E-18 T 14-10-2018 IPR001310 Histidine triad (HIT) protein LH59_00925 deca6aca880fb6cf14e3e13259a15617 122 PRINTS PR00332 Histidine triad family signature 27 45 2.5E-18 T 14-10-2018 IPR001310 Histidine triad (HIT) protein LH59_00925 deca6aca880fb6cf14e3e13259a15617 122 Gene3D G3DSA:3.30.428.10 1 115 1.5E-40 T 14-10-2018 IPR036265 HIT-like superfamily LH59_07790 41fe7d39c57f1229093dd3cca3e26c94 303 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 222 234 - T 14-10-2018 IPR033749 Polyprenyl synthetase, conserved site LH59_07790 41fe7d39c57f1229093dd3cca3e26c94 303 SUPERFAMILY SSF48576 8 292 1.67E-81 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily LH59_07790 41fe7d39c57f1229093dd3cca3e26c94 303 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 92 108 - T 14-10-2018 IPR033749 Polyprenyl synthetase, conserved site LH59_07790 41fe7d39c57f1229093dd3cca3e26c94 303 Gene3D G3DSA:1.10.600.10 9 303 9.3E-91 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily LH59_07790 41fe7d39c57f1229093dd3cca3e26c94 303 Pfam PF00348 Polyprenyl synthetase 36 266 3.3E-52 T 14-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 LH59_10125 5a3ad0755a7e4df206aa6fd5cf3bb0bd 337 Pfam PF13379 NMT1-like family 23 266 1.4E-28 T 14-10-2018 LH59_10125 5a3ad0755a7e4df206aa6fd5cf3bb0bd 337 Gene3D G3DSA:3.40.190.10 22 150 1.1E-16 T 14-10-2018 LH59_10125 5a3ad0755a7e4df206aa6fd5cf3bb0bd 337 Gene3D G3DSA:3.40.190.10 170 337 1.6E-24 T 14-10-2018 LH59_10125 5a3ad0755a7e4df206aa6fd5cf3bb0bd 337 SUPERFAMILY SSF53850 27 288 1.59E-28 T 14-10-2018 LH59_05150 539d72afea603c10556956fa90e47c84 127 SUPERFAMILY SSF52833 23 95 1.17E-15 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_05150 539d72afea603c10556956fa90e47c84 127 Pfam PF00085 Thioredoxin 15 86 1.6E-9 T 14-10-2018 IPR013766 Thioredoxin domain GO:0045454 LH59_05150 539d72afea603c10556956fa90e47c84 127 Gene3D G3DSA:3.40.30.10 9 111 4.5E-13 T 14-10-2018 LH59_10345 e110755e7b177f36c008dc4dc6bd56d8 487 SUPERFAMILY SSF48452 108 158 7.59E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_10345 e110755e7b177f36c008dc4dc6bd56d8 487 Gene3D G3DSA:1.25.40.10 109 193 2.3E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_10345 e110755e7b177f36c008dc4dc6bd56d8 487 SUPERFAMILY SSF56935 192 400 3.05E-5 T 14-10-2018 LH59_10345 e110755e7b177f36c008dc4dc6bd56d8 487 Pfam PF04575 Protein of unknown function (DUF560) 190 487 7.1E-52 T 14-10-2018 IPR007655 Protein of unknown function DUF560 LH59_11605 b4319a17068e2921a8b851d6725cdab3 279 Pfam PF05036 Sporulation related domain 201 276 5.5E-17 T 14-10-2018 IPR007730 Sporulation-like domain GO:0042834 LH59_11605 b4319a17068e2921a8b851d6725cdab3 279 PRINTS PR01217 Proline rich extensin signature 73 94 1.6E-10 T 14-10-2018 LH59_11605 b4319a17068e2921a8b851d6725cdab3 279 PRINTS PR01217 Proline rich extensin signature 94 110 1.6E-10 T 14-10-2018 LH59_11605 b4319a17068e2921a8b851d6725cdab3 279 PRINTS PR01217 Proline rich extensin signature 116 133 1.6E-10 T 14-10-2018 LH59_11605 b4319a17068e2921a8b851d6725cdab3 279 PRINTS PR01217 Proline rich extensin signature 134 159 1.6E-10 T 14-10-2018 LH59_11605 b4319a17068e2921a8b851d6725cdab3 279 Gene3D G3DSA:3.30.70.1070 198 279 6.4E-10 T 14-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 LH59_11605 b4319a17068e2921a8b851d6725cdab3 279 SUPERFAMILY SSF110997 202 276 2.09E-13 T 14-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 LH59_09200 e9b11ff27e2623336de97bc8ece5b5c8 368 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 2 350 9.1E-147 T 14-10-2018 IPR016496 GTPase HflX GO:0005525 LH59_09200 e9b11ff27e2623336de97bc8ece5b5c8 368 PIRSF PIRSF006809 1 362 9.7E-135 T 14-10-2018 IPR016496 GTPase HflX GO:0005525 LH59_09200 e9b11ff27e2623336de97bc8ece5b5c8 368 Hamap MF_00900 GTPase HflX [hflX]. 19 355 45.737 T 14-10-2018 IPR016496 GTPase HflX GO:0005525 LH59_09200 e9b11ff27e2623336de97bc8ece5b5c8 368 Pfam PF01926 50S ribosome-binding GTPase 192 310 9.0E-21 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 LH59_09200 e9b11ff27e2623336de97bc8ece5b5c8 368 Pfam PF16360 GTP-binding GTPase Middle Region 106 184 9.7E-29 T 14-10-2018 IPR032305 GTP-binding protein, middle domain LH59_09200 e9b11ff27e2623336de97bc8ece5b5c8 368 Gene3D G3DSA:3.40.50.300 191 355 7.4E-40 T 14-10-2018 LH59_09200 e9b11ff27e2623336de97bc8ece5b5c8 368 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 259 277 9.8E-8 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 LH59_09200 e9b11ff27e2623336de97bc8ece5b5c8 368 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 192 212 9.8E-8 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 LH59_09200 e9b11ff27e2623336de97bc8ece5b5c8 368 Gene3D G3DSA:3.40.50.11060 12 130 1.7E-34 T 14-10-2018 LH59_09200 e9b11ff27e2623336de97bc8ece5b5c8 368 Pfam PF13167 GTP-binding GTPase N-terminal 18 104 2.5E-27 T 14-10-2018 IPR025121 GTPase HflX, N-terminal LH59_09200 e9b11ff27e2623336de97bc8ece5b5c8 368 SUPERFAMILY SSF52540 190 350 1.92E-39 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_18260 dd19e4fd46572e03a3038e64354744df 274 SUPERFAMILY SSF46689 172 223 7.62E-8 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_18260 dd19e4fd46572e03a3038e64354744df 274 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 226 267 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 LH59_18260 dd19e4fd46572e03a3038e64354744df 274 Gene3D G3DSA:1.10.10.60 168 272 1.3E-24 T 14-10-2018 LH59_18260 dd19e4fd46572e03a3038e64354744df 274 SMART SM00342 189 271 5.0E-28 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_18260 dd19e4fd46572e03a3038e64354744df 274 Pfam PF12833 Helix-turn-helix domain 195 269 5.4E-19 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_18260 dd19e4fd46572e03a3038e64354744df 274 SUPERFAMILY SSF46689 226 270 2.76E-8 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_14260 1e906b6471a2bc026d67993adc30125d 401 Gene3D G3DSA:3.90.1150.10 262 393 7.4E-39 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_14260 1e906b6471a2bc026d67993adc30125d 401 TIGRFAM TIGR01324 cysta_beta_ly_B: cystathionine beta-lyase 10 392 1.9E-115 T 14-10-2018 IPR006233 Cystathionine beta-lyase, bacterial GO:0004121|GO:0005737|GO:0006520 KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8 LH59_14260 1e906b6471a2bc026d67993adc30125d 401 Gene3D G3DSA:3.40.640.10 4 261 3.6E-67 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_14260 1e906b6471a2bc026d67993adc30125d 401 PIRSF PIRSF001434 1 394 1.5E-121 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 LH59_14260 1e906b6471a2bc026d67993adc30125d 401 SUPERFAMILY SSF53383 29 392 2.09E-87 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_14260 1e906b6471a2bc026d67993adc30125d 401 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 10 390 1.0E-98 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 LH59_02160 238ca64f942d50d2b66ad40cbf1f197b 246 SUPERFAMILY SSF52096 5 246 5.42E-66 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily LH59_02160 238ca64f942d50d2b66ad40cbf1f197b 246 Gene3D G3DSA:1.10.12.10 196 246 7.9E-9 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal LH59_02160 238ca64f942d50d2b66ad40cbf1f197b 246 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 244 6.1E-40 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 LH59_02160 238ca64f942d50d2b66ad40cbf1f197b 246 Gene3D G3DSA:3.90.226.10 4 195 1.6E-52 T 14-10-2018 LH59_19215 ca02a6d0dda7fd8f1e948da5ccfd1475 431 Pfam PF00155 Aminotransferase class I and II 147 426 1.0E-30 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LH59_19215 ca02a6d0dda7fd8f1e948da5ccfd1475 431 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 69 1.5E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_19215 ca02a6d0dda7fd8f1e948da5ccfd1475 431 Gene3D G3DSA:3.90.1150.10 89 420 6.5E-49 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_19215 ca02a6d0dda7fd8f1e948da5ccfd1475 431 SUPERFAMILY SSF46785 8 74 1.51E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_19215 ca02a6d0dda7fd8f1e948da5ccfd1475 431 Gene3D G3DSA:3.40.640.10 117 331 6.5E-49 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_19215 ca02a6d0dda7fd8f1e948da5ccfd1475 431 SUPERFAMILY SSF53383 72 427 1.39E-62 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_19215 ca02a6d0dda7fd8f1e948da5ccfd1475 431 SMART SM00345 11 70 5.4E-15 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_19215 ca02a6d0dda7fd8f1e948da5ccfd1475 431 Gene3D G3DSA:1.10.10.10 9 81 6.2E-13 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_03870 5cf84e23b168ff5f8b2587770c329c4f 301 SUPERFAMILY SSF51735 15 177 2.63E-50 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_03870 5cf84e23b168ff5f8b2587770c329c4f 301 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 179 298 3.5E-34 T 14-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 LH59_03870 5cf84e23b168ff5f8b2587770c329c4f 301 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 16 176 7.3E-47 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 LH59_03870 5cf84e23b168ff5f8b2587770c329c4f 301 PIRSF PIRSF000103 10 301 9.7E-73 T 14-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 LH59_03870 5cf84e23b168ff5f8b2587770c329c4f 301 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 19 32 - T 14-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 LH59_03870 5cf84e23b168ff5f8b2587770c329c4f 301 SUPERFAMILY SSF48179 177 300 6.91E-41 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 LH59_03870 5cf84e23b168ff5f8b2587770c329c4f 301 Gene3D G3DSA:1.10.1040.10 177 301 3.4E-40 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 LH59_03870 5cf84e23b168ff5f8b2587770c329c4f 301 Gene3D G3DSA:3.40.50.720 12 176 3.2E-50 T 14-10-2018 LH59_13370 f94fd93322a20ebedc2784acedc45bb8 402 TIGRFAM TIGR02120 GspF: type II secretion system protein F 4 401 3.8E-153 T 14-10-2018 IPR011850 General secretion pathway protein F GO:0008565|GO:0015627|GO:0015628 LH59_13370 f94fd93322a20ebedc2784acedc45bb8 402 Pfam PF00482 Type II secretion system (T2SS), protein F 69 191 9.8E-32 T 14-10-2018 IPR018076 Type II secretion system F domain LH59_13370 f94fd93322a20ebedc2784acedc45bb8 402 Pfam PF00482 Type II secretion system (T2SS), protein F 271 393 6.8E-28 T 14-10-2018 IPR018076 Type II secretion system F domain LH59_13370 f94fd93322a20ebedc2784acedc45bb8 402 Gene3D G3DSA:1.20.81.30 54 170 4.3E-29 T 14-10-2018 LH59_13370 f94fd93322a20ebedc2784acedc45bb8 402 Gene3D G3DSA:1.20.81.30 254 367 5.5E-26 T 14-10-2018 LH59_13370 f94fd93322a20ebedc2784acedc45bb8 402 PRINTS PR00812 Bacterial general secretion pathway protein F signature 64 76 1.0E-27 T 14-10-2018 IPR003004 GspF/PilC family LH59_13370 f94fd93322a20ebedc2784acedc45bb8 402 PRINTS PR00812 Bacterial general secretion pathway protein F signature 382 401 1.0E-27 T 14-10-2018 IPR003004 GspF/PilC family LH59_13370 f94fd93322a20ebedc2784acedc45bb8 402 PRINTS PR00812 Bacterial general secretion pathway protein F signature 366 380 1.0E-27 T 14-10-2018 IPR003004 GspF/PilC family LH59_13370 f94fd93322a20ebedc2784acedc45bb8 402 PRINTS PR00812 Bacterial general secretion pathway protein F signature 163 191 1.0E-27 T 14-10-2018 IPR003004 GspF/PilC family LH59_11710 c2f8a9c3a75e3e842cd3cdd0a19a9abe 398 Hamap MF_00392 Lipid-A-disaccharide synthase [lpxB]. 2 395 34.706 T 14-10-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 LH59_11710 c2f8a9c3a75e3e842cd3cdd0a19a9abe 398 Pfam PF02684 Lipid-A-disaccharide synthetase 6 389 1.7E-89 T 14-10-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 LH59_11710 c2f8a9c3a75e3e842cd3cdd0a19a9abe 398 SUPERFAMILY SSF53756 3 369 2.83E-27 T 14-10-2018 LH59_11710 c2f8a9c3a75e3e842cd3cdd0a19a9abe 398 TIGRFAM TIGR00215 lpxB: lipid-A-disaccharide synthase 5 392 2.0E-94 T 14-10-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 LH59_18195 7f990ed87b0e7f71ca757ee0b64b0a57 144 SUPERFAMILY SSF110857 2 117 1.44E-19 T 14-10-2018 IPR036568 Gamma-glutamyl cyclotransferase-like superfamily LH59_18195 7f990ed87b0e7f71ca757ee0b64b0a57 144 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 5 131 1.7E-15 T 14-10-2018 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like LH59_18195 7f990ed87b0e7f71ca757ee0b64b0a57 144 Gene3D G3DSA:3.10.490.10 1 129 3.5E-16 T 14-10-2018 LH59_00900 4b6c05df37568ef9e680b0f844cc6988 386 SMART SM00228 286 369 1.2E-12 T 14-10-2018 IPR001478 PDZ domain GO:0005515 LH59_00900 4b6c05df37568ef9e680b0f844cc6988 386 Gene3D G3DSA:2.30.42.10 281 382 5.7E-27 T 14-10-2018 LH59_00900 4b6c05df37568ef9e680b0f844cc6988 386 Gene3D G3DSA:2.40.10.120 57 280 3.5E-75 T 14-10-2018 LH59_00900 4b6c05df37568ef9e680b0f844cc6988 386 Pfam PF13365 Trypsin-like peptidase domain 112 247 2.7E-35 T 14-10-2018 LH59_00900 4b6c05df37568ef9e680b0f844cc6988 386 SUPERFAMILY SSF50156 244 370 9.33E-23 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 LH59_00900 4b6c05df37568ef9e680b0f844cc6988 386 PRINTS PR00834 HtrA/DegQ protease family signature 142 162 1.2E-54 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 LH59_00900 4b6c05df37568ef9e680b0f844cc6988 386 PRINTS PR00834 HtrA/DegQ protease family signature 121 133 1.2E-54 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 LH59_00900 4b6c05df37568ef9e680b0f844cc6988 386 PRINTS PR00834 HtrA/DegQ protease family signature 218 235 1.2E-54 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 LH59_00900 4b6c05df37568ef9e680b0f844cc6988 386 PRINTS PR00834 HtrA/DegQ protease family signature 183 207 1.2E-54 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 LH59_00900 4b6c05df37568ef9e680b0f844cc6988 386 PRINTS PR00834 HtrA/DegQ protease family signature 327 339 1.2E-54 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 LH59_00900 4b6c05df37568ef9e680b0f844cc6988 386 PRINTS PR00834 HtrA/DegQ protease family signature 240 257 1.2E-54 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 LH59_00900 4b6c05df37568ef9e680b0f844cc6988 386 Pfam PF13180 PDZ domain 287 377 9.0E-15 T 14-10-2018 IPR001478 PDZ domain GO:0005515 LH59_00900 4b6c05df37568ef9e680b0f844cc6988 386 SUPERFAMILY SSF50494 56 281 2.1E-64 T 14-10-2018 IPR009003 Peptidase S1, PA clan LH59_07040 f955a6b7a2e59aa54c0b95eedca6a273 695 SUPERFAMILY SSF52540 3 649 7.24E-23 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_07040 f955a6b7a2e59aa54c0b95eedca6a273 695 Pfam PF13307 Helicase C-terminal domain 512 676 2.6E-32 T 14-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 LH59_07040 f955a6b7a2e59aa54c0b95eedca6a273 695 Gene3D G3DSA:3.40.50.300 496 694 1.3E-33 T 14-10-2018 LH59_07040 f955a6b7a2e59aa54c0b95eedca6a273 695 SUPERFAMILY SSF52540 518 650 1.36E-7 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_07040 f955a6b7a2e59aa54c0b95eedca6a273 695 Pfam PF06733 DEAD_2 177 253 6.9E-5 T 14-10-2018 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 LH59_07040 f955a6b7a2e59aa54c0b95eedca6a273 695 SMART SM00491 533 663 1.9E-27 T 14-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 LH59_07040 f955a6b7a2e59aa54c0b95eedca6a273 695 Gene3D G3DSA:3.40.50.300 23 284 9.9E-47 T 14-10-2018 LH59_06280 e0f067196fb8c2a9c8d8185aa9cb67ff 225 Gene3D G3DSA:3.40.50.300 1 223 2.9E-59 T 14-10-2018 LH59_06280 e0f067196fb8c2a9c8d8185aa9cb67ff 225 SUPERFAMILY SSF52540 4 213 1.27E-49 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_06280 e0f067196fb8c2a9c8d8185aa9cb67ff 225 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_06280 e0f067196fb8c2a9c8d8185aa9cb67ff 225 Pfam PF00005 ABC transporter 26 161 2.4E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_06280 e0f067196fb8c2a9c8d8185aa9cb67ff 225 SMART SM00382 26 206 1.2E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_22870 dafea246103ab04a2df235107f58ecb5 1231 Pfam PF05359 Domain of Unknown Function (DUF748) 485 606 2.4E-10 T 14-10-2018 IPR008023 Protein of unknown function DUF748 LH59_22870 dafea246103ab04a2df235107f58ecb5 1231 Pfam PF05359 Domain of Unknown Function (DUF748) 837 983 9.2E-38 T 14-10-2018 IPR008023 Protein of unknown function DUF748 LH59_22870 dafea246103ab04a2df235107f58ecb5 1231 Pfam PF05359 Domain of Unknown Function (DUF748) 616 759 1.6E-21 T 14-10-2018 IPR008023 Protein of unknown function DUF748 LH59_22870 dafea246103ab04a2df235107f58ecb5 1231 Pfam PF05359 Domain of Unknown Function (DUF748) 157 309 2.7E-20 T 14-10-2018 IPR008023 Protein of unknown function DUF748 LH59_11440 e600255b875b636bbe47fa466beea961 558 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 3 361 3.1E-76 T 14-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 LH59_11440 e600255b875b636bbe47fa466beea961 558 PRINTS PR01005 Flagellar hook-associated protein signature 476 497 2.0E-39 T 14-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 LH59_11440 e600255b875b636bbe47fa466beea961 558 PRINTS PR01005 Flagellar hook-associated protein signature 10 33 2.0E-39 T 14-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 LH59_11440 e600255b875b636bbe47fa466beea961 558 PRINTS PR01005 Flagellar hook-associated protein signature 48 70 2.0E-39 T 14-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 LH59_11440 e600255b875b636bbe47fa466beea961 558 PRINTS PR01005 Flagellar hook-associated protein signature 523 547 2.0E-39 T 14-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 LH59_11440 e600255b875b636bbe47fa466beea961 558 PRINTS PR01005 Flagellar hook-associated protein signature 155 179 2.0E-39 T 14-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 LH59_11440 e600255b875b636bbe47fa466beea961 558 PRINTS PR01005 Flagellar hook-associated protein signature 364 386 2.0E-39 T 14-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 LH59_11440 e600255b875b636bbe47fa466beea961 558 PRINTS PR01005 Flagellar hook-associated protein signature 122 142 2.0E-39 T 14-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 LH59_11440 e600255b875b636bbe47fa466beea961 558 PRINTS PR01005 Flagellar hook-associated protein signature 450 469 2.0E-39 T 14-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 LH59_11440 e600255b875b636bbe47fa466beea961 558 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 511 556 2.6E-6 T 14-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain LH59_11440 e600255b875b636bbe47fa466beea961 558 SUPERFAMILY SSF64518 133 556 3.66E-35 T 14-10-2018 LH59_28195 44fcc1be1efcafd688578c23ecadea48 324 SUPERFAMILY SSF161098 90 304 6.7E-18 T 14-10-2018 IPR035906 MetI-like superfamily LH59_28195 44fcc1be1efcafd688578c23ecadea48 324 Gene3D G3DSA:1.10.3720.10 83 315 4.3E-23 T 14-10-2018 IPR035906 MetI-like superfamily LH59_28195 44fcc1be1efcafd688578c23ecadea48 324 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 319 8.5E-40 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_10430 4c4b674c04e2ddace418ddee296d393c 226 PIRSF PIRSF002764 3 225 4.0E-67 T 14-10-2018 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria LH59_10430 4c4b674c04e2ddace418ddee296d393c 226 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 32 53 8.1E-54 T 14-10-2018 LH59_10430 4c4b674c04e2ddace418ddee296d393c 226 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 81 104 8.1E-54 T 14-10-2018 LH59_10430 4c4b674c04e2ddace418ddee296d393c 226 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 160 179 8.1E-54 T 14-10-2018 LH59_10430 4c4b674c04e2ddace418ddee296d393c 226 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 198 221 8.1E-54 T 14-10-2018 LH59_10430 4c4b674c04e2ddace418ddee296d393c 226 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 58 75 8.1E-54 T 14-10-2018 LH59_10430 4c4b674c04e2ddace418ddee296d393c 226 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 137 160 8.1E-54 T 14-10-2018 LH59_10430 4c4b674c04e2ddace418ddee296d393c 226 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 106 124 8.1E-54 T 14-10-2018 LH59_10430 4c4b674c04e2ddace418ddee296d393c 226 TIGRFAM TIGR01190 ccmB: heme exporter protein CcmB 11 221 3.1E-59 T 14-10-2018 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria LH59_10430 4c4b674c04e2ddace418ddee296d393c 226 Pfam PF03379 CcmB protein 9 221 1.3E-62 T 14-10-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 LH59_10490 309fe5c035f9e1ad67a4dca12ef7f518 667 Pfam PF01578 Cytochrome C assembly protein 89 295 9.1E-50 T 14-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 LH59_10490 309fe5c035f9e1ad67a4dca12ef7f518 667 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 210 236 9.2E-91 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 LH59_10490 309fe5c035f9e1ad67a4dca12ef7f518 667 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 80 106 9.2E-91 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 LH59_10490 309fe5c035f9e1ad67a4dca12ef7f518 667 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 274 294 9.2E-91 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 LH59_10490 309fe5c035f9e1ad67a4dca12ef7f518 667 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 132 149 9.2E-91 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 LH59_10490 309fe5c035f9e1ad67a4dca12ef7f518 667 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 159 181 9.2E-91 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 LH59_10490 309fe5c035f9e1ad67a4dca12ef7f518 667 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 294 310 9.2E-91 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 LH59_10490 309fe5c035f9e1ad67a4dca12ef7f518 667 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 244 264 9.2E-91 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 LH59_10490 309fe5c035f9e1ad67a4dca12ef7f518 667 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 310 329 9.2E-91 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 LH59_10490 309fe5c035f9e1ad67a4dca12ef7f518 667 TIGRFAM TIGR00353 nrfE: cytochrome c-type biogenesis protein CcmF 53 645 1.7E-222 T 14-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 LH59_10490 309fe5c035f9e1ad67a4dca12ef7f518 667 Pfam PF16327 Cytochrome c-type biogenesis protein CcmF C-terminal 315 642 3.7E-122 T 14-10-2018 IPR032523 Cytochrome c-type biogenesis protein CcmF, C-terminal LH59_10490 309fe5c035f9e1ad67a4dca12ef7f518 667 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 394 413 1.5E-53 T 14-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 LH59_10490 309fe5c035f9e1ad67a4dca12ef7f518 667 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 4 28 1.5E-53 T 14-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 LH59_10490 309fe5c035f9e1ad67a4dca12ef7f518 667 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 313 328 1.5E-53 T 14-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 LH59_10490 309fe5c035f9e1ad67a4dca12ef7f518 667 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 635 648 1.5E-53 T 14-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 LH59_10490 309fe5c035f9e1ad67a4dca12ef7f518 667 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 113 136 1.5E-53 T 14-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 LH59_10490 309fe5c035f9e1ad67a4dca12ef7f518 667 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 189 204 1.5E-53 T 14-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 LH59_10490 309fe5c035f9e1ad67a4dca12ef7f518 667 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 351 368 1.5E-53 T 14-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 LH59_10080 695cd609dae2d140ce348990482bac1c 220 SUPERFAMILY SSF52218 8 209 2.1E-31 T 14-10-2018 IPR029039 Flavoprotein-like superfamily LH59_10080 695cd609dae2d140ce348990482bac1c 220 Pfam PF02525 Flavodoxin-like fold 8 168 2.7E-19 T 14-10-2018 IPR003680 Flavodoxin-like fold LH59_10080 695cd609dae2d140ce348990482bac1c 220 Gene3D G3DSA:3.40.50.360 6 189 2.3E-29 T 14-10-2018 IPR029039 Flavoprotein-like superfamily LH59_06215 75a03f5237dfee56c27911a62560fce7 182 PIRSF PIRSF000239 1 182 6.3E-38 T 14-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 LH59_06215 75a03f5237dfee56c27911a62560fce7 182 SUPERFAMILY SSF52833 4 181 1.83E-43 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_06215 75a03f5237dfee56c27911a62560fce7 182 Pfam PF00578 AhpC/TSA family 6 143 4.9E-24 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 LH59_06215 75a03f5237dfee56c27911a62560fce7 182 Gene3D G3DSA:3.40.30.10 7 182 4.4E-46 T 14-10-2018 LH59_19945 980367cb901f602d3e3dff35ba67f6ba 753 Gene3D G3DSA:3.40.50.300 465 747 3.0E-61 T 14-10-2018 LH59_19945 980367cb901f602d3e3dff35ba67f6ba 753 Pfam PF13807 G-rich domain on putative tyrosine kinase 391 472 2.5E-30 T 14-10-2018 IPR032807 Tyrosine kinase, G-rich domain LH59_19945 980367cb901f602d3e3dff35ba67f6ba 753 TIGRFAM TIGR01005 eps_transp_fam: exopolysaccharide transport protein family 21 745 6.3E-144 T 14-10-2018 IPR005700 Exopolysaccharide biosynthesis protein ExoP-like GO:0045226 LH59_19945 980367cb901f602d3e3dff35ba67f6ba 753 Pfam PF13614 AAA domain 559 675 5.4E-8 T 14-10-2018 IPR025669 AAA domain LH59_19945 980367cb901f602d3e3dff35ba67f6ba 753 SUPERFAMILY SSF52540 550 728 2.49E-32 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_19945 980367cb901f602d3e3dff35ba67f6ba 753 Pfam PF02706 Chain length determinant protein 25 110 2.1E-11 T 14-10-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 LH59_25450 997661130c87340eac5170e0191798e8 86 SUPERFAMILY SSF47413 7 70 2.41E-16 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 LH59_25450 997661130c87340eac5170e0191798e8 86 Pfam PF01381 Helix-turn-helix 16 67 6.0E-12 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LH59_25450 997661130c87340eac5170e0191798e8 86 Gene3D G3DSA:1.10.260.40 1 86 1.3E-14 T 14-10-2018 LH59_25450 997661130c87340eac5170e0191798e8 86 SMART SM00530 15 70 8.7E-10 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LH59_10355 7fda4ecca79611a5ebbf3c86d06d7e08 945 Gene3D G3DSA:2.40.170.20 313 945 1.4E-101 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_10355 7fda4ecca79611a5ebbf3c86d06d7e08 945 Gene3D G3DSA:2.170.130.10 176 312 3.6E-28 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily LH59_10355 7fda4ecca79611a5ebbf3c86d06d7e08 945 SUPERFAMILY SSF56935 153 944 3.0E-98 T 14-10-2018 LH59_10355 7fda4ecca79611a5ebbf3c86d06d7e08 945 Gene3D G3DSA:3.55.50.30 76 147 2.2E-25 T 14-10-2018 LH59_10355 7fda4ecca79611a5ebbf3c86d06d7e08 945 Pfam PF00593 TonB dependent receptor 439 944 8.9E-33 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_10355 7fda4ecca79611a5ebbf3c86d06d7e08 945 Pfam PF07715 TonB-dependent Receptor Plug Domain 197 302 2.0E-12 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_10355 7fda4ecca79611a5ebbf3c86d06d7e08 945 SMART SM00965 98 149 7.2E-10 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 LH59_10625 18541360dca3155dccc729ca94a3d7f8 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 2.5E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10625 18541360dca3155dccc729ca94a3d7f8 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 2.5E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10625 18541360dca3155dccc729ca94a3d7f8 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 2.5E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10625 18541360dca3155dccc729ca94a3d7f8 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 246 5.7E-61 T 14-10-2018 LH59_10625 18541360dca3155dccc729ca94a3d7f8 247 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 191 2.9E-4 T 14-10-2018 LH59_10625 18541360dca3155dccc729ca94a3d7f8 247 Gene3D G3DSA:3.40.50.720 1 246 6.7E-78 T 14-10-2018 LH59_10625 18541360dca3155dccc729ca94a3d7f8 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 2.4E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10625 18541360dca3155dccc729ca94a3d7f8 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 2.4E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10625 18541360dca3155dccc729ca94a3d7f8 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.4E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10625 18541360dca3155dccc729ca94a3d7f8 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 2.4E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10625 18541360dca3155dccc729ca94a3d7f8 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 2.4E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10625 18541360dca3155dccc729ca94a3d7f8 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 2.4E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10625 18541360dca3155dccc729ca94a3d7f8 247 SUPERFAMILY SSF51735 8 246 6.48E-79 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_26165 7d30a96b3e73558a6fbb1951d6764dae 299 Pfam PF00892 EamA-like transporter family 155 282 7.9E-16 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_26165 7d30a96b3e73558a6fbb1951d6764dae 299 SUPERFAMILY SSF103481 52 143 4.32E-6 T 14-10-2018 LH59_26165 7d30a96b3e73558a6fbb1951d6764dae 299 SUPERFAMILY SSF103481 202 285 1.96E-7 T 14-10-2018 LH59_21355 9e1d23689f87559c29361f70e2b354b1 383 Gene3D G3DSA:1.20.140.10 239 383 5.5E-12 T 14-10-2018 LH59_21355 9e1d23689f87559c29361f70e2b354b1 383 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 128 223 2.5E-22 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 LH59_21355 9e1d23689f87559c29361f70e2b354b1 383 Gene3D G3DSA:2.40.110.10 127 238 6.7E-33 T 14-10-2018 LH59_21355 9e1d23689f87559c29361f70e2b354b1 383 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 12 124 6.1E-21 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 LH59_21355 9e1d23689f87559c29361f70e2b354b1 383 SUPERFAMILY SSF47203 235 379 4.0E-5 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 LH59_21355 9e1d23689f87559c29361f70e2b354b1 383 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 268 380 1.9E-4 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LH59_21355 9e1d23689f87559c29361f70e2b354b1 383 SUPERFAMILY SSF56645 12 245 2.23E-62 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 LH59_21355 9e1d23689f87559c29361f70e2b354b1 383 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 130 142 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 LH59_21355 9e1d23689f87559c29361f70e2b354b1 383 Gene3D G3DSA:1.10.540.10 12 125 3.5E-23 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 LH59_27020 0aed091de055ebcd17a56178f4283d7b 224 SUPERFAMILY SSF100950 12 205 5.44E-41 T 14-10-2018 IPR037171 NagB/RpiA transferase-like LH59_27020 0aed091de055ebcd17a56178f4283d7b 224 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 13 199 2.7E-37 T 14-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase LH59_27020 0aed091de055ebcd17a56178f4283d7b 224 PIRSF PIRSF006806 8 202 6.2E-24 T 14-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase LH59_27020 0aed091de055ebcd17a56178f4283d7b 224 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 12 199 4.2E-26 T 14-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase LH59_27020 0aed091de055ebcd17a56178f4283d7b 224 Gene3D G3DSA:3.40.50.10420 11 211 1.9E-39 T 14-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily LH59_07765 43de35e115452ce02f5571d14bf0094c 382 SUPERFAMILY SSF50022 7 156 1.96E-28 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 LH59_07765 43de35e115452ce02f5571d14bf0094c 382 Gene3D G3DSA:2.102.10.10 37 165 1.3E-40 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 LH59_07765 43de35e115452ce02f5571d14bf0094c 382 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 24 49 4.4E-5 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 LH59_07765 43de35e115452ce02f5571d14bf0094c 382 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 74 94 4.4E-5 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 LH59_07765 43de35e115452ce02f5571d14bf0094c 382 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 177 380 1.0E-34 T 14-10-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0044237|GO:0051537|GO:0055114 LH59_07765 43de35e115452ce02f5571d14bf0094c 382 Gene3D G3DSA:3.90.380.10 16 374 1.3E-40 T 14-10-2018 LH59_07765 43de35e115452ce02f5571d14bf0094c 382 Pfam PF00355 Rieske [2Fe-2S] domain 42 136 9.0E-9 T 14-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 LH59_07765 43de35e115452ce02f5571d14bf0094c 382 SUPERFAMILY SSF55961 160 378 1.33E-45 T 14-10-2018 LH59_12895 e214a4846c9ecd6596f4a96170ebee53 367 Gene3D G3DSA:3.40.710.10 39 151 2.2E-24 T 14-10-2018 LH59_12895 e214a4846c9ecd6596f4a96170ebee53 367 Pfam PF00144 Beta-lactamase 45 343 4.5E-35 T 14-10-2018 IPR001466 Beta-lactamase-related LH59_12895 e214a4846c9ecd6596f4a96170ebee53 367 Gene3D G3DSA:3.40.710.10 152 359 4.6E-23 T 14-10-2018 LH59_12895 e214a4846c9ecd6596f4a96170ebee53 367 SUPERFAMILY SSF56601 36 349 2.38E-46 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like LH59_25055 f7d69c4ecae01dd249b285012418be71 477 TIGRFAM TIGR02485 CobZ_N-term: precorrin 3B synthase CobZ 2 458 8.0E-210 T 14-10-2018 IPR012831 Precorrin 3B synthase CobZ LH59_25055 f7d69c4ecae01dd249b285012418be71 477 SUPERFAMILY SSF51905 2 461 4.91E-39 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_25055 f7d69c4ecae01dd249b285012418be71 477 Gene3D G3DSA:3.90.700.10 235 396 7.5E-89 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 LH59_25055 f7d69c4ecae01dd249b285012418be71 477 SUPERFAMILY SSF56425 234 395 8.02E-23 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 LH59_25055 f7d69c4ecae01dd249b285012418be71 477 Gene3D G3DSA:3.50.50.60 2 454 7.5E-89 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_25055 f7d69c4ecae01dd249b285012418be71 477 Pfam PF00890 FAD binding domain 3 431 7.8E-36 T 14-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 LH59_27295 a2d401b7d110bff6abde106e70853fa1 350 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 142 256 1.6E-22 T 14-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 LH59_27295 a2d401b7d110bff6abde106e70853fa1 350 SUPERFAMILY SSF51735 6 165 8.26E-45 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_27295 a2d401b7d110bff6abde106e70853fa1 350 SUPERFAMILY SSF55347 139 286 7.68E-35 T 14-10-2018 LH59_27295 a2d401b7d110bff6abde106e70853fa1 350 Gene3D G3DSA:3.30.360.10 138 340 3.5E-123 T 14-10-2018 LH59_27295 a2d401b7d110bff6abde106e70853fa1 350 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 11 128 9.6E-29 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 LH59_27295 a2d401b7d110bff6abde106e70853fa1 350 Gene3D G3DSA:3.40.50.720 11 321 3.5E-123 T 14-10-2018 LH59_17055 370df3e8a26cd49e9f77b757ce113fab 426 Pfam PF02687 FtsX-like permease family 312 419 3.2E-13 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 LH59_17055 370df3e8a26cd49e9f77b757ce113fab 426 TIGRFAM TIGR02212 lolCE: lipoprotein releasing system, transmembrane protein, LolC/E family 6 425 3.0E-139 T 14-10-2018 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E GO:0016021|GO:0042953|GO:0042954 LH59_17055 370df3e8a26cd49e9f77b757ce113fab 426 Pfam PF12704 MacB-like periplasmic core domain 38 255 1.3E-18 T 14-10-2018 IPR025857 MacB-like periplasmic core domain LH59_07310 0daf0455311da3d33e80514c1fca3ce8 405 Hamap MF_00994 Lipopolysaccharide assembly protein B [lapB]. 6 403 32.904 T 14-10-2018 IPR030865 Lipopolysaccharide assembly protein B GO:0008653 LH59_07310 0daf0455311da3d33e80514c1fca3ce8 405 SUPERFAMILY SSF48452 40 204 7.38E-11 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_07310 0daf0455311da3d33e80514c1fca3ce8 405 Gene3D G3DSA:1.25.40.10 21 195 1.6E-13 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_15350 d68b2b214a0b8eaaaf461d2464c63677 403 Gene3D G3DSA:1.10.230.10 260 356 1.5E-42 T 14-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain LH59_15350 d68b2b214a0b8eaaaf461d2464c63677 403 Gene3D G3DSA:1.10.580.10 88 382 1.5E-42 T 14-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 LH59_15350 d68b2b214a0b8eaaaf461d2464c63677 403 Gene3D G3DSA:1.10.1660.10 1 55 6.7E-6 T 14-10-2018 LH59_15350 d68b2b214a0b8eaaaf461d2464c63677 403 PRINTS PR00143 Citrate synthase signature 362 376 8.0E-12 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 LH59_15350 d68b2b214a0b8eaaaf461d2464c63677 403 PRINTS PR00143 Citrate synthase signature 212 227 8.0E-12 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 LH59_15350 d68b2b214a0b8eaaaf461d2464c63677 403 PRINTS PR00143 Citrate synthase signature 234 262 8.0E-12 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 LH59_15350 d68b2b214a0b8eaaaf461d2464c63677 403 PRINTS PR00143 Citrate synthase signature 342 358 8.0E-12 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 LH59_15350 d68b2b214a0b8eaaaf461d2464c63677 403 Pfam PF00285 Citrate synthase, C-terminal domain 71 392 2.0E-59 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 LH59_15350 d68b2b214a0b8eaaaf461d2464c63677 403 Pfam PF12728 Helix-turn-helix domain 4 55 9.1E-7 T 14-10-2018 LH59_15350 d68b2b214a0b8eaaaf461d2464c63677 403 SUPERFAMILY SSF48256 33 400 6.15E-71 T 14-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 LH59_06235 3ac8498342efc38a9f2e080a388747e0 309 SMART SM00987 151 303 2.0E-42 T 14-10-2018 LH59_06235 3ac8498342efc38a9f2e080a388747e0 309 SUPERFAMILY SSF52141 125 307 4.91E-61 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 LH59_06235 3ac8498342efc38a9f2e080a388747e0 309 Pfam PF03167 Uracil DNA glycosylase superfamily 151 303 4.8E-47 T 14-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 LH59_06235 3ac8498342efc38a9f2e080a388747e0 309 SMART SM00986 151 303 2.0E-42 T 14-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 LH59_06235 3ac8498342efc38a9f2e080a388747e0 309 Gene3D G3DSA:3.40.470.10 125 309 1.1E-70 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 LH59_06235 3ac8498342efc38a9f2e080a388747e0 309 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 137 303 2.4E-63 T 14-10-2018 IPR005273 Uracil-DNA glycosylase family 4 LH59_04675 a3b6cd679d6d4861b439f32fa8dabf74 326 Gene3D G3DSA:3.40.190.10 127 251 3.7E-102 T 14-10-2018 LH59_04675 a3b6cd679d6d4861b439f32fa8dabf74 326 PIRSF PIRSF017082 1 324 3.2E-77 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_04675 a3b6cd679d6d4861b439f32fa8dabf74 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 322 2.2E-81 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_04675 a3b6cd679d6d4861b439f32fa8dabf74 326 Gene3D G3DSA:3.40.190.150 29 316 3.7E-102 T 14-10-2018 LH59_04675 a3b6cd679d6d4861b439f32fa8dabf74 326 SUPERFAMILY SSF53850 110 286 3.37E-12 T 14-10-2018 LH59_15755 28f62681d0122efb10972f20a98e900f 237 Gene3D G3DSA:3.40.50.300 6 233 6.8E-68 T 14-10-2018 LH59_15755 28f62681d0122efb10972f20a98e900f 237 SUPERFAMILY SSF52540 13 227 2.45E-72 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_15755 28f62681d0122efb10972f20a98e900f 237 SMART SM00382 37 227 6.4E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_15755 28f62681d0122efb10972f20a98e900f 237 Pfam PF00005 ABC transporter 28 174 1.7E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_15755 28f62681d0122efb10972f20a98e900f 237 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_12040 9234e0885043fd58fb505e6aabed4d91 322 Pfam PF13437 HlyD family secretion protein 203 314 7.9E-16 T 14-10-2018 LH59_12040 9234e0885043fd58fb505e6aabed4d91 322 Gene3D G3DSA:1.10.287.470 104 171 1.7E-5 T 14-10-2018 LH59_12040 9234e0885043fd58fb505e6aabed4d91 322 Gene3D G3DSA:1.10.287.470 74 96 3.3E-5 T 14-10-2018 LH59_12040 9234e0885043fd58fb505e6aabed4d91 322 Gene3D G3DSA:2.40.30.170 216 322 2.2E-10 T 14-10-2018 LH59_12040 9234e0885043fd58fb505e6aabed4d91 322 Gene3D G3DSA:2.40.50.100 43 73 3.3E-5 T 14-10-2018 LH59_12040 9234e0885043fd58fb505e6aabed4d91 322 SUPERFAMILY SSF111369 144 268 1.18E-6 T 14-10-2018 LH59_17640 38e11b72f5aa79992841813b1749d59c 878 SMART SM00965 59 110 1.7E-11 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 LH59_17640 38e11b72f5aa79992841813b1749d59c 878 Gene3D G3DSA:2.40.170.20 267 878 1.3E-26 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_17640 38e11b72f5aa79992841813b1749d59c 878 SUPERFAMILY SSF56935 133 878 4.53E-51 T 14-10-2018 LH59_17640 38e11b72f5aa79992841813b1749d59c 878 Pfam PF07715 TonB-dependent Receptor Plug Domain 134 251 9.3E-7 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_17640 38e11b72f5aa79992841813b1749d59c 878 Gene3D G3DSA:3.55.50.30 29 131 3.3E-23 T 14-10-2018 LH59_09730 fd1936552cdb4aaa46568701ac2f968b 132 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 115 6.4E-8 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain LH59_09730 fd1936552cdb4aaa46568701ac2f968b 132 SUPERFAMILY SSF54593 4 125 9.4E-22 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_09730 fd1936552cdb4aaa46568701ac2f968b 132 Gene3D G3DSA:3.10.180.10 4 120 2.8E-23 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_06650 83ee184540d9f631dda0bf260bdabb5b 219 Gene3D G3DSA:3.90.1720.10 83 215 4.5E-41 T 14-10-2018 LH59_06650 83ee184540d9f631dda0bf260bdabb5b 219 Pfam PF00877 NlpC/P60 family 100 206 3.5E-28 T 14-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain LH59_06650 83ee184540d9f631dda0bf260bdabb5b 219 SUPERFAMILY SSF54001 88 207 1.8E-39 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily LH59_14435 b77fdb20d80cf6910c0311a1ba03581c 396 Gene3D G3DSA:3.40.190.10 38 121 6.0E-15 T 14-10-2018 LH59_14435 b77fdb20d80cf6910c0311a1ba03581c 396 Gene3D G3DSA:3.40.190.10 168 387 1.1E-36 T 14-10-2018 LH59_14435 b77fdb20d80cf6910c0311a1ba03581c 396 Pfam PF13379 NMT1-like family 37 275 1.0E-47 T 14-10-2018 LH59_14435 b77fdb20d80cf6910c0311a1ba03581c 396 SUPERFAMILY SSF53850 40 272 7.14E-39 T 14-10-2018 LH59_12175 8a1662c10840bdfd7e555f5386ebfd03 375 Gene3D G3DSA:1.10.540.10 1 118 3.8E-43 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 LH59_12175 8a1662c10840bdfd7e555f5386ebfd03 375 Gene3D G3DSA:2.40.110.10 119 231 2.1E-42 T 14-10-2018 LH59_12175 8a1662c10840bdfd7e555f5386ebfd03 375 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 4 115 2.4E-34 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 LH59_12175 8a1662c10840bdfd7e555f5386ebfd03 375 SUPERFAMILY SSF47203 225 375 4.51E-58 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 LH59_12175 8a1662c10840bdfd7e555f5386ebfd03 375 PIRSF PIRSF016578 3 194 1.9E-10 T 14-10-2018 LH59_12175 8a1662c10840bdfd7e555f5386ebfd03 375 PIRSF PIRSF016578 219 373 6.0E-11 T 14-10-2018 LH59_12175 8a1662c10840bdfd7e555f5386ebfd03 375 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 122 134 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 LH59_12175 8a1662c10840bdfd7e555f5386ebfd03 375 Gene3D G3DSA:1.20.140.10 232 375 3.2E-55 T 14-10-2018 LH59_12175 8a1662c10840bdfd7e555f5386ebfd03 375 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 227 375 6.6E-51 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LH59_12175 8a1662c10840bdfd7e555f5386ebfd03 375 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 120 214 2.0E-25 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 LH59_12175 8a1662c10840bdfd7e555f5386ebfd03 375 SUPERFAMILY SSF56645 2 240 7.07E-81 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 LH59_12175 8a1662c10840bdfd7e555f5386ebfd03 375 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 334 353 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 LH59_27545 c714628252ca5c542a89a519813e66c5 400 Gene3D G3DSA:3.90.1150.10 23 394 1.1E-135 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_27545 c714628252ca5c542a89a519813e66c5 400 SUPERFAMILY SSF53383 9 398 2.28E-103 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_27545 c714628252ca5c542a89a519813e66c5 400 Pfam PF00155 Aminotransferase class I and II 49 387 1.6E-32 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LH59_27545 c714628252ca5c542a89a519813e66c5 400 Gene3D G3DSA:3.40.640.10 70 289 1.1E-135 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_18945 0298a8c9fff442de068fd47ef1607144 318 Pfam PF16220 Domain of unknown function (DUF4880) 17 56 3.2E-10 T 14-10-2018 IPR032623 FecR, N-terminal LH59_18945 0298a8c9fff442de068fd47ef1607144 318 PIRSF PIRSF018266 7 318 2.2E-61 T 14-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component LH59_18945 0298a8c9fff442de068fd47ef1607144 318 Gene3D G3DSA:2.60.120.1440 117 242 5.1E-7 T 14-10-2018 LH59_18945 0298a8c9fff442de068fd47ef1607144 318 Pfam PF04773 FecR protein 118 206 7.9E-12 T 14-10-2018 IPR006860 FecR protein LH59_02700 3a1a6397b642ff665808a64e3863f593 406 SUPERFAMILY SSF54373 185 283 2.35E-14 T 14-10-2018 LH59_02700 3a1a6397b642ff665808a64e3863f593 406 Gene3D G3DSA:3.30.9.30 45 364 5.4E-116 T 14-10-2018 LH59_02700 3a1a6397b642ff665808a64e3863f593 406 Gene3D G3DSA:3.50.50.60 13 356 5.4E-116 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_02700 3a1a6397b642ff665808a64e3863f593 406 SUPERFAMILY SSF51905 12 366 1.4E-60 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_02700 3a1a6397b642ff665808a64e3863f593 406 Pfam PF01494 FAD binding domain 12 325 1.8E-26 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 LH59_02700 3a1a6397b642ff665808a64e3863f593 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 160 175 2.8E-20 T 14-10-2018 LH59_02700 3a1a6397b642ff665808a64e3863f593 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 340 356 2.8E-20 T 14-10-2018 LH59_02700 3a1a6397b642ff665808a64e3863f593 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 306 322 2.8E-20 T 14-10-2018 LH59_02700 3a1a6397b642ff665808a64e3863f593 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 12 34 2.8E-20 T 14-10-2018 LH59_02700 3a1a6397b642ff665808a64e3863f593 406 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 291 306 2.8E-20 T 14-10-2018 LH59_07560 def3bd83e47e2a7aeca4186f4fbacfad 327 Gene3D G3DSA:3.40.1010.20 17 288 2.1E-113 T 14-10-2018 LH59_07560 def3bd83e47e2a7aeca4186f4fbacfad 327 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 12 294 38.142 T 14-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 LH59_07560 def3bd83e47e2a7aeca4186f4fbacfad 327 Gene3D G3DSA:3.40.1010.20 108 204 2.1E-113 T 14-10-2018 LH59_07560 def3bd83e47e2a7aeca4186f4fbacfad 327 Gene3D G3DSA:3.40.50.11270 23 107 2.1E-113 T 14-10-2018 LH59_07560 def3bd83e47e2a7aeca4186f4fbacfad 327 Pfam PF02401 LytB protein 14 290 4.8E-93 T 14-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 LH59_07560 def3bd83e47e2a7aeca4186f4fbacfad 327 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 14 292 1.3E-100 T 14-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 LH59_06640 ca43d5c4d005d9ef73fd8a9bc04ddee4 314 SUPERFAMILY SSF46785 13 112 8.71E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_06640 ca43d5c4d005d9ef73fd8a9bc04ddee4 314 Gene3D G3DSA:3.40.190.10 93 308 6.0E-89 T 14-10-2018 LH59_06640 ca43d5c4d005d9ef73fd8a9bc04ddee4 314 SUPERFAMILY SSF53850 92 303 4.58E-37 T 14-10-2018 LH59_06640 ca43d5c4d005d9ef73fd8a9bc04ddee4 314 Gene3D G3DSA:3.40.190.10 167 272 6.0E-89 T 14-10-2018 LH59_06640 ca43d5c4d005d9ef73fd8a9bc04ddee4 314 Pfam PF03466 LysR substrate binding domain 90 297 1.1E-37 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_06640 ca43d5c4d005d9ef73fd8a9bc04ddee4 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 4.3E-11 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_06640 ca43d5c4d005d9ef73fd8a9bc04ddee4 314 Gene3D G3DSA:1.10.10.10 1 86 4.7E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_06640 ca43d5c4d005d9ef73fd8a9bc04ddee4 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 4.3E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_06640 ca43d5c4d005d9ef73fd8a9bc04ddee4 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 4.3E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_06640 ca43d5c4d005d9ef73fd8a9bc04ddee4 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 4.3E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_03745 b2d99069f55db93d3fd9ea413350990a 114 TIGRFAM TIGR01244 TIGR01244: TIGR01244 family protein 5 111 3.1E-25 T 14-10-2018 IPR005939 Beta-lactamase hydrolase-like GO:0016787 LH59_03745 b2d99069f55db93d3fd9ea413350990a 114 Pfam PF04273 Putative phosphatase (DUF442) 7 113 3.3E-27 T 14-10-2018 IPR005939 Beta-lactamase hydrolase-like GO:0016787 LH59_03745 b2d99069f55db93d3fd9ea413350990a 114 Gene3D G3DSA:3.90.190.10 2 114 5.9E-26 T 14-10-2018 IPR029021 Protein-tyrosine phosphatase-like LH59_05535 f572cc1608e61f65d4bc8332e6650736 448 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 248 423 2.0E-33 T 14-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 LH59_05535 f572cc1608e61f65d4bc8332e6650736 448 PRINTS PR00981 Seryl-tRNA synthetase signature 288 300 4.0E-31 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 LH59_05535 f572cc1608e61f65d4bc8332e6650736 448 PRINTS PR00981 Seryl-tRNA synthetase signature 357 373 4.0E-31 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 LH59_05535 f572cc1608e61f65d4bc8332e6650736 448 PRINTS PR00981 Seryl-tRNA synthetase signature 340 353 4.0E-31 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 LH59_05535 f572cc1608e61f65d4bc8332e6650736 448 PRINTS PR00981 Seryl-tRNA synthetase signature 375 391 4.0E-31 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 LH59_05535 f572cc1608e61f65d4bc8332e6650736 448 PRINTS PR00981 Seryl-tRNA synthetase signature 300 313 4.0E-31 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 LH59_05535 f572cc1608e61f65d4bc8332e6650736 448 Gene3D G3DSA:3.30.930.10 105 447 2.2E-109 T 14-10-2018 LH59_05535 f572cc1608e61f65d4bc8332e6650736 448 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 445 38.777 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 LH59_05535 f572cc1608e61f65d4bc8332e6650736 448 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 440 6.7E-152 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 LH59_05535 f572cc1608e61f65d4bc8332e6650736 448 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 107 1.3E-28 T 14-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 LH59_05535 f572cc1608e61f65d4bc8332e6650736 448 PIRSF PIRSF001529 1 448 1.4E-164 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 LH59_05535 f572cc1608e61f65d4bc8332e6650736 448 SUPERFAMILY SSF46589 1 112 1.52E-29 T 14-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 LH59_05535 f572cc1608e61f65d4bc8332e6650736 448 SUPERFAMILY SSF55681 136 442 4.71E-95 T 14-10-2018 LH59_05535 f572cc1608e61f65d4bc8332e6650736 448 Gene3D G3DSA:1.10.287.40 1 104 4.3E-22 T 14-10-2018 LH59_19495 017e8380210f70330807351f3e14e581 320 Gene3D G3DSA:3.40.50.1980 12 314 4.6E-63 T 14-10-2018 LH59_19495 017e8380210f70330807351f3e14e581 320 Pfam PF01497 Periplasmic binding protein 67 247 4.2E-15 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain LH59_19495 017e8380210f70330807351f3e14e581 320 SUPERFAMILY SSF53807 30 307 2.32E-40 T 14-10-2018 LH59_19990 1d5910c59eed0df7ffdcb06fb0907809 438 Pfam PF01943 Polysaccharide biosynthesis protein 15 291 1.4E-17 T 14-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 LH59_07245 40043493c2e70cf4a9ac4be4e37c7f0d 224 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 100 179 9.6E-8 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 LH59_07245 40043493c2e70cf4a9ac4be4e37c7f0d 224 Gene3D G3DSA:1.10.150.240 17 84 4.6E-52 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 LH59_07245 40043493c2e70cf4a9ac4be4e37c7f0d 224 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 184 1.0E-31 T 14-10-2018 LH59_07245 40043493c2e70cf4a9ac4be4e37c7f0d 224 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 69 183 1.4E-10 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 LH59_07245 40043493c2e70cf4a9ac4be4e37c7f0d 224 SUPERFAMILY SSF56784 4 215 1.36E-51 T 14-10-2018 IPR036412 HAD-like superfamily LH59_07245 40043493c2e70cf4a9ac4be4e37c7f0d 224 Gene3D G3DSA:3.40.50.1000 5 190 4.6E-52 T 14-10-2018 IPR023214 HAD superfamily LH59_07245 40043493c2e70cf4a9ac4be4e37c7f0d 224 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 5 192 3.4E-51 T 14-10-2018 IPR006346 2-phosphoglycolate phosphatase-like, prokaryotic GO:0016791 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 LH59_17795 7a06c46a40e412fad7ca1ea5827b23e9 141 SUPERFAMILY SSF82784 2 139 8.64E-41 T 14-10-2018 IPR036102 OsmC/Ohr superfamily LH59_17795 7a06c46a40e412fad7ca1ea5827b23e9 141 Pfam PF02566 OsmC-like protein 40 136 1.4E-20 T 14-10-2018 IPR003718 OsmC/Ohr family LH59_17795 7a06c46a40e412fad7ca1ea5827b23e9 141 TIGRFAM TIGR03562 osmo_induc_OsmC: peroxiredoxin, OsmC subfamily 2 137 1.3E-61 T 14-10-2018 IPR019904 Peroxiredoxin OsmC GO:0004601|GO:0006979 KEGG: 00480+1.11.1.15 LH59_17795 7a06c46a40e412fad7ca1ea5827b23e9 141 Gene3D G3DSA:3.30.300.20 1 141 6.3E-47 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta LH59_20055 0fb2f13beb83606bea3f4fe1939cc5de 644 SUPERFAMILY SSF52096 6 265 4.98E-55 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily LH59_20055 0fb2f13beb83606bea3f4fe1939cc5de 644 Pfam PF00378 Enoyl-CoA hydratase/isomerase 17 202 4.0E-28 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 LH59_20055 0fb2f13beb83606bea3f4fe1939cc5de 644 SUPERFAMILY SSF51735 304 481 4.33E-41 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_20055 0fb2f13beb83606bea3f4fe1939cc5de 644 SUPERFAMILY SSF48179 482 578 2.04E-27 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 LH59_20055 0fb2f13beb83606bea3f4fe1939cc5de 644 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 483 572 6.0E-22 T 14-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 LH59_20055 0fb2f13beb83606bea3f4fe1939cc5de 644 Gene3D G3DSA:3.90.226.10 6 297 5.1E-68 T 14-10-2018 LH59_20055 0fb2f13beb83606bea3f4fe1939cc5de 644 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 306 478 1.8E-43 T 14-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 LH59_20055 0fb2f13beb83606bea3f4fe1939cc5de 644 SUPERFAMILY SSF48179 589 639 3.74E-6 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 LH59_20055 0fb2f13beb83606bea3f4fe1939cc5de 644 Gene3D G3DSA:3.40.50.720 298 485 1.4E-50 T 14-10-2018 LH59_20055 0fb2f13beb83606bea3f4fe1939cc5de 644 Gene3D G3DSA:1.10.1040.50 486 644 3.4E-40 T 14-10-2018 LH59_11745 eae70bb51b6ff409125a3d26698aaffc 245 Gene3D G3DSA:3.40.50.880 21 241 2.5E-51 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_11745 eae70bb51b6ff409125a3d26698aaffc 245 SUPERFAMILY SSF52317 44 212 5.59E-42 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_11745 eae70bb51b6ff409125a3d26698aaffc 245 Pfam PF00117 Glutamine amidotransferase class-I 31 197 2.1E-20 T 14-10-2018 IPR017926 Glutamine amidotransferase LH59_26100 5ec96f088eea6c83217e1f5ddd9127fa 271 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 24 267 2.2E-62 T 14-10-2018 LH59_26100 5ec96f088eea6c83217e1f5ddd9127fa 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 104 1.5E-33 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_26100 5ec96f088eea6c83217e1f5ddd9127fa 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 156 1.5E-33 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_26100 5ec96f088eea6c83217e1f5ddd9127fa 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 188 205 1.5E-33 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_26100 5ec96f088eea6c83217e1f5ddd9127fa 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 186 1.5E-33 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_26100 5ec96f088eea6c83217e1f5ddd9127fa 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 230 250 1.5E-33 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_26100 5ec96f088eea6c83217e1f5ddd9127fa 271 SUPERFAMILY SSF51735 12 267 2.13E-75 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_26100 5ec96f088eea6c83217e1f5ddd9127fa 271 Gene3D G3DSA:3.40.50.720 6 269 1.3E-82 T 14-10-2018 LH59_26100 5ec96f088eea6c83217e1f5ddd9127fa 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 93 104 6.8E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_26100 5ec96f088eea6c83217e1f5ddd9127fa 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 154 6.8E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_26100 5ec96f088eea6c83217e1f5ddd9127fa 271 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 167 186 6.8E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_26100 5ec96f088eea6c83217e1f5ddd9127fa 271 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 154 182 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LH59_02685 1b30bd6c9e29a329c4a247b739565b4d 322 Pfam PF02653 Branched-chain amino acid transport system / permease component 30 303 2.6E-36 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_15870 4b36f7b2c816bf077bcaa3530cdc8ae1 212 SUPERFAMILY SSF46689 16 99 5.64E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_15870 4b36f7b2c816bf077bcaa3530cdc8ae1 212 SUPERFAMILY SSF48498 95 210 3.18E-26 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily LH59_15870 4b36f7b2c816bf077bcaa3530cdc8ae1 212 Gene3D G3DSA:1.10.357.10 86 211 6.8E-32 T 14-10-2018 LH59_15870 4b36f7b2c816bf077bcaa3530cdc8ae1 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 75 1.2E-12 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_15870 4b36f7b2c816bf077bcaa3530cdc8ae1 212 Gene3D G3DSA:1.10.10.60 15 82 1.2E-27 T 14-10-2018 LH59_25915 710e819a5e6d386e46e9bc181efc51e3 948 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 145 156 - T 14-10-2018 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 LH59_25915 710e819a5e6d386e46e9bc181efc51e3 948 SUPERFAMILY SSF51621 15 948 2.04E-285 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 LH59_25915 710e819a5e6d386e46e9bc181efc51e3 948 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 763 789 1.9E-53 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 LH59_25915 710e819a5e6d386e46e9bc181efc51e3 948 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 409 429 1.9E-53 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 LH59_25915 710e819a5e6d386e46e9bc181efc51e3 948 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 258 273 1.9E-53 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 LH59_25915 710e819a5e6d386e46e9bc181efc51e3 948 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 144 157 1.9E-53 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 LH59_25915 710e819a5e6d386e46e9bc181efc51e3 948 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 582 602 1.9E-53 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 LH59_25915 710e819a5e6d386e46e9bc181efc51e3 948 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 624 653 1.9E-53 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 LH59_25915 710e819a5e6d386e46e9bc181efc51e3 948 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 196 212 1.9E-53 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 LH59_25915 710e819a5e6d386e46e9bc181efc51e3 948 Pfam PF00311 Phosphoenolpyruvate carboxylase 141 948 2.7E-285 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 LH59_25915 710e819a5e6d386e46e9bc181efc51e3 948 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 584 596 - T 14-10-2018 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 LH59_25915 710e819a5e6d386e46e9bc181efc51e3 948 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 7 948 18.89 T 14-10-2018 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 LH59_25915 710e819a5e6d386e46e9bc181efc51e3 948 Gene3D G3DSA:1.20.1440.90 289 412 6.3E-5 T 14-10-2018 LH59_26635 967af201865b0f9b1e527db16f3b56ef 264 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_26635 967af201865b0f9b1e527db16f3b56ef 264 Gene3D G3DSA:3.40.50.300 20 264 1.7E-69 T 14-10-2018 LH59_26635 967af201865b0f9b1e527db16f3b56ef 264 Pfam PF00005 ABC transporter 38 189 6.5E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_26635 967af201865b0f9b1e527db16f3b56ef 264 TIGRFAM TIGR04406 LPS_export_lptB: LPS export ABC transporter ATP-binding protein 22 264 2.1E-114 T 14-10-2018 IPR030921 LPS export ABC transporter, ATP-binding protein LptB GO:0043190|GO:0055085 LH59_26635 967af201865b0f9b1e527db16f3b56ef 264 SMART SM00382 46 239 7.7E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_26635 967af201865b0f9b1e527db16f3b56ef 264 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 237 259 4.9E-7 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal LH59_26635 967af201865b0f9b1e527db16f3b56ef 264 SUPERFAMILY SSF52540 22 260 2.32E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_03575 747839d0f01f574cc9ffcbd5371e924f 472 SUPERFAMILY SSF54106 325 370 2.35E-6 T 14-10-2018 LH59_03575 747839d0f01f574cc9ffcbd5371e924f 472 Gene3D G3DSA:3.10.350.10 318 375 2.6E-8 T 14-10-2018 IPR036779 LysM domain superfamily LH59_03575 747839d0f01f574cc9ffcbd5371e924f 472 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 117 145 - T 14-10-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 LH59_03575 747839d0f01f574cc9ffcbd5371e924f 472 SUPERFAMILY SSF53955 96 243 6.84E-41 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily LH59_03575 747839d0f01f574cc9ffcbd5371e924f 472 SUPERFAMILY SSF54106 422 466 1.24E-10 T 14-10-2018 LH59_03575 747839d0f01f574cc9ffcbd5371e924f 472 Gene3D G3DSA:1.10.530.10 94 243 2.8E-31 T 14-10-2018 LH59_03575 747839d0f01f574cc9ffcbd5371e924f 472 Pfam PF01476 LysM domain 330 370 2.5E-6 T 14-10-2018 IPR018392 LysM domain LH59_03575 747839d0f01f574cc9ffcbd5371e924f 472 Pfam PF01476 LysM domain 424 466 1.0E-13 T 14-10-2018 IPR018392 LysM domain LH59_03575 747839d0f01f574cc9ffcbd5371e924f 472 Pfam PF01464 Transglycosylase SLT domain 107 207 1.2E-23 T 14-10-2018 IPR008258 Transglycosylase SLT domain 1 LH59_03575 747839d0f01f574cc9ffcbd5371e924f 472 Gene3D G3DSA:3.10.350.10 421 466 8.8E-16 T 14-10-2018 IPR036779 LysM domain superfamily LH59_03575 747839d0f01f574cc9ffcbd5371e924f 472 SMART SM00257 423 466 4.0E-16 T 14-10-2018 IPR018392 LysM domain LH59_03575 747839d0f01f574cc9ffcbd5371e924f 472 SMART SM00257 326 370 0.0032 T 14-10-2018 IPR018392 LysM domain LH59_14045 b6cd4f1de8bc12685b089b6782da48a2 504 Gene3D G3DSA:3.40.50.1100 12 318 4.7E-131 T 14-10-2018 LH59_14045 b6cd4f1de8bc12685b089b6782da48a2 504 Gene3D G3DSA:3.40.1020.10 329 504 2.1E-68 T 14-10-2018 IPR038110 Threonine dehydratase, ACT-like domain superfamily KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 LH59_14045 b6cd4f1de8bc12685b089b6782da48a2 504 SUPERFAMILY SSF55021 328 413 1.01E-23 T 14-10-2018 LH59_14045 b6cd4f1de8bc12685b089b6782da48a2 504 TIGRFAM TIGR01124 ilvA_2Cterm: threonine ammonia-lyase, biosynthetic 2 503 1.3E-231 T 14-10-2018 IPR005787 Threonine dehydratase, biosynthetic GO:0004794|GO:0009097 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 LH59_14045 b6cd4f1de8bc12685b089b6782da48a2 504 Gene3D G3DSA:3.40.50.1100 48 147 4.7E-131 T 14-10-2018 LH59_14045 b6cd4f1de8bc12685b089b6782da48a2 504 SUPERFAMILY SSF53686 3 356 3.14E-94 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme LH59_14045 b6cd4f1de8bc12685b089b6782da48a2 504 SUPERFAMILY SSF55021 410 503 1.9E-23 T 14-10-2018 LH59_14045 b6cd4f1de8bc12685b089b6782da48a2 504 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 16 307 8.7E-77 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme LH59_14045 b6cd4f1de8bc12685b089b6782da48a2 504 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 421 503 1.8E-19 T 14-10-2018 IPR001721 Threonine dehydratase, ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 LH59_14045 b6cd4f1de8bc12685b089b6782da48a2 504 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 321 409 2.3E-24 T 14-10-2018 IPR001721 Threonine dehydratase, ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 LH59_24615 30d33a363b7b5421dd871f55547a20aa 242 Gene3D G3DSA:1.20.120.530 98 242 8.9E-31 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_24615 30d33a363b7b5421dd871f55547a20aa 242 Gene3D G3DSA:1.10.10.10 17 82 2.3E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_24615 30d33a363b7b5421dd871f55547a20aa 242 SUPERFAMILY SSF48008 102 240 3.66E-28 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_24615 30d33a363b7b5421dd871f55547a20aa 242 SUPERFAMILY SSF46785 13 85 1.23E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_24615 30d33a363b7b5421dd871f55547a20aa 242 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 80 4.9E-23 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_24615 30d33a363b7b5421dd871f55547a20aa 242 SMART SM00895 105 233 1.9E-22 T 14-10-2018 IPR011711 GntR, C-terminal LH59_24615 30d33a363b7b5421dd871f55547a20aa 242 Pfam PF07729 FCD domain 106 232 1.3E-23 T 14-10-2018 IPR011711 GntR, C-terminal LH59_24615 30d33a363b7b5421dd871f55547a20aa 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 55 71 2.3E-10 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_24615 30d33a363b7b5421dd871f55547a20aa 242 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 55 2.3E-10 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_24615 30d33a363b7b5421dd871f55547a20aa 242 SMART SM00345 22 81 1.5E-22 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_13375 ac72d88e120c8eb5f2cfa1953e6a8948 411 Gene3D G3DSA:3.40.190.10 126 274 6.1E-122 T 14-10-2018 LH59_13375 ac72d88e120c8eb5f2cfa1953e6a8948 411 SUPERFAMILY SSF53850 29 404 2.25E-46 T 14-10-2018 LH59_13375 ac72d88e120c8eb5f2cfa1953e6a8948 411 Gene3D G3DSA:3.40.190.260 29 406 6.1E-122 T 14-10-2018 LH59_13375 ac72d88e120c8eb5f2cfa1953e6a8948 411 Pfam PF12849 PBP superfamily domain 22 350 3.5E-32 T 14-10-2018 IPR024370 PBP domain LH59_13275 1eb1aa5162e4a619d67c8af73dc27729 590 Gene3D G3DSA:3.50.50.60 477 580 2.6E-10 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_13275 1eb1aa5162e4a619d67c8af73dc27729 590 Gene3D G3DSA:3.50.50.60 249 365 1.1E-8 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_13275 1eb1aa5162e4a619d67c8af73dc27729 590 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 9 31 2.2E-5 T 14-10-2018 LH59_13275 1eb1aa5162e4a619d67c8af73dc27729 590 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 155 170 2.2E-5 T 14-10-2018 LH59_13275 1eb1aa5162e4a619d67c8af73dc27729 590 SUPERFAMILY SSF54373 414 492 1.1E-6 T 14-10-2018 LH59_13275 1eb1aa5162e4a619d67c8af73dc27729 590 SUPERFAMILY SSF51905 8 581 9.5E-57 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_13275 1eb1aa5162e4a619d67c8af73dc27729 590 Gene3D G3DSA:3.50.50.60 3 170 1.0E-11 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_13275 1eb1aa5162e4a619d67c8af73dc27729 590 Pfam PF05199 GMC oxidoreductase 448 570 4.8E-21 T 14-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 LH59_13275 1eb1aa5162e4a619d67c8af73dc27729 590 Pfam PF00732 GMC oxidoreductase 234 347 1.1E-12 T 14-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 LH59_15945 33da904a0060e514624cdc971ed82086 136 Gene3D G3DSA:1.10.1660.10 2 136 2.5E-27 T 14-10-2018 LH59_15945 33da904a0060e514624cdc971ed82086 136 SUPERFAMILY SSF46955 1 111 1.17E-26 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily LH59_15945 33da904a0060e514624cdc971ed82086 136 SMART SM00422 1 70 1.8E-21 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LH59_15945 33da904a0060e514624cdc971ed82086 136 Pfam PF13411 MerR HTH family regulatory protein 1 68 4.7E-15 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LH59_15945 33da904a0060e514624cdc971ed82086 136 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 2.8E-7 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LH59_15945 33da904a0060e514624cdc971ed82086 136 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 2.8E-7 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LH59_15945 33da904a0060e514624cdc971ed82086 136 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 2.8E-7 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LH59_15945 33da904a0060e514624cdc971ed82086 136 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LH59_14455 36c7e12adb982865e63f7406168b25e4 307 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 258 299 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 LH59_14455 36c7e12adb982865e63f7406168b25e4 307 Gene3D G3DSA:1.10.10.60 206 306 1.4E-26 T 14-10-2018 LH59_14455 36c7e12adb982865e63f7406168b25e4 307 SUPERFAMILY SSF46689 257 305 2.96E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_14455 36c7e12adb982865e63f7406168b25e4 307 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 287 303 7.5E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 LH59_14455 36c7e12adb982865e63f7406168b25e4 307 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 272 287 7.5E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 LH59_14455 36c7e12adb982865e63f7406168b25e4 307 SMART SM00342 221 303 5.3E-31 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_14455 36c7e12adb982865e63f7406168b25e4 307 SUPERFAMILY SSF46689 205 253 6.57E-7 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_14455 36c7e12adb982865e63f7406168b25e4 307 Pfam PF12852 Cupin 18 188 8.3E-33 T 14-10-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain LH59_14455 36c7e12adb982865e63f7406168b25e4 307 Pfam PF12833 Helix-turn-helix domain 227 304 7.7E-21 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_21025 2a84f2f755d7d24cedfe25e01ed525e5 230 Gene3D G3DSA:1.10.3720.10 7 223 1.6E-43 T 14-10-2018 IPR035906 MetI-like superfamily LH59_21025 2a84f2f755d7d24cedfe25e01ed525e5 230 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 18 116 2.7E-21 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 LH59_21025 2a84f2f755d7d24cedfe25e01ed525e5 230 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 39 215 6.1E-18 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_21025 2a84f2f755d7d24cedfe25e01ed525e5 230 SUPERFAMILY SSF161098 18 208 1.57E-39 T 14-10-2018 IPR035906 MetI-like superfamily LH59_06260 7782faeae1b9f4770d14eb870943b01b 258 SUPERFAMILY SSF54534 100 219 1.11E-30 T 14-10-2018 LH59_06260 7782faeae1b9f4770d14eb870943b01b 258 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 157 178 - T 14-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 LH59_06260 7782faeae1b9f4770d14eb870943b01b 258 Gene3D G3DSA:1.10.4030.30 22 87 6.5E-6 T 14-10-2018 LH59_06260 7782faeae1b9f4770d14eb870943b01b 258 Pfam PF13616 PPIC-type PPIASE domain 119 220 3.6E-25 T 14-10-2018 LH59_06260 7782faeae1b9f4770d14eb870943b01b 258 Gene3D G3DSA:3.10.50.40 124 223 8.4E-33 T 14-10-2018 LH59_24715 29f6eacdadba35a387c1fec9c10c1657 341 Pfam PF01370 NAD dependent epimerase/dehydratase family 19 264 8.2E-58 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 LH59_24715 29f6eacdadba35a387c1fec9c10c1657 341 PRINTS PR01713 Nucleotide sugar epimerase signature 234 249 3.9E-6 T 14-10-2018 LH59_24715 29f6eacdadba35a387c1fec9c10c1657 341 PRINTS PR01713 Nucleotide sugar epimerase signature 45 61 3.9E-6 T 14-10-2018 LH59_24715 29f6eacdadba35a387c1fec9c10c1657 341 PRINTS PR01713 Nucleotide sugar epimerase signature 302 319 3.9E-6 T 14-10-2018 LH59_24715 29f6eacdadba35a387c1fec9c10c1657 341 SUPERFAMILY SSF51735 16 339 3.31E-87 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_24715 29f6eacdadba35a387c1fec9c10c1657 341 Gene3D G3DSA:3.40.50.720 20 323 1.1E-113 T 14-10-2018 LH59_24715 29f6eacdadba35a387c1fec9c10c1657 341 Gene3D G3DSA:3.90.25.10 194 335 1.1E-113 T 14-10-2018 LH59_04540 29891e6297b259a334680c525844d969 397 Gene3D G3DSA:3.40.50.10540 8 390 1.2E-116 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily LH59_04540 29891e6297b259a334680c525844d969 397 Pfam PF02515 CoA-transferase family III 9 374 3.2E-109 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 LH59_04540 29891e6297b259a334680c525844d969 397 SUPERFAMILY SSF89796 3 397 3.01E-125 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily LH59_04540 29891e6297b259a334680c525844d969 397 Gene3D G3DSA:3.30.1540.10 234 327 1.2E-116 T 14-10-2018 LH59_13830 3feec031c07f33c8703333cf8929c6f1 795 Pfam PF07660 Secretin and TonB N terminus short domain 47 95 9.3E-8 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 LH59_13830 3feec031c07f33c8703333cf8929c6f1 795 SUPERFAMILY SSF56935 109 795 3.4E-97 T 14-10-2018 LH59_13830 3feec031c07f33c8703333cf8929c6f1 795 Gene3D G3DSA:2.40.170.20 248 794 2.4E-67 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_13830 3feec031c07f33c8703333cf8929c6f1 795 Pfam PF00593 TonB dependent receptor 317 792 1.1E-46 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_13830 3feec031c07f33c8703333cf8929c6f1 795 Gene3D G3DSA:3.55.50.30 17 118 7.4E-24 T 14-10-2018 LH59_13830 3feec031c07f33c8703333cf8929c6f1 795 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 126 777 5.4E-114 T 14-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 LH59_13830 3feec031c07f33c8703333cf8929c6f1 795 Gene3D G3DSA:2.170.130.10 123 230 4.0E-19 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily LH59_13830 3feec031c07f33c8703333cf8929c6f1 795 Pfam PF07715 TonB-dependent Receptor Plug Domain 125 223 1.1E-17 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_13830 3feec031c07f33c8703333cf8929c6f1 795 SMART SM00965 47 97 3.5E-11 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 LH59_11425 0a659b57b8f9132ae5ca4a139c1260b9 230 Pfam PF02107 Flagellar L-ring protein 48 229 1.0E-57 T 14-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 LH59_11425 0a659b57b8f9132ae5ca4a139c1260b9 230 Hamap MF_00415 Flagellar L-ring protein [flgH]. 6 228 26.483 T 14-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 LH59_11425 0a659b57b8f9132ae5ca4a139c1260b9 230 PRINTS PR01008 Flagellar L-ring protein signature 191 205 6.3E-27 T 14-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 LH59_11425 0a659b57b8f9132ae5ca4a139c1260b9 230 PRINTS PR01008 Flagellar L-ring protein signature 207 221 6.3E-27 T 14-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 LH59_11425 0a659b57b8f9132ae5ca4a139c1260b9 230 PRINTS PR01008 Flagellar L-ring protein signature 170 186 6.3E-27 T 14-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 LH59_11425 0a659b57b8f9132ae5ca4a139c1260b9 230 PRINTS PR01008 Flagellar L-ring protein signature 72 84 6.3E-27 T 14-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 LH59_11425 0a659b57b8f9132ae5ca4a139c1260b9 230 PRINTS PR01008 Flagellar L-ring protein signature 144 159 6.3E-27 T 14-10-2018 IPR000527 Flagellar L-ring protein GO:0003774|GO:0009427|GO:0071973 LH59_23740 242a727fa0eae7b79dd59f204193989e 368 PRINTS PR00184 Neisseria sp. porin signature 56 81 1.5E-8 T 14-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 LH59_23740 242a727fa0eae7b79dd59f204193989e 368 PRINTS PR00184 Neisseria sp. porin signature 156 173 1.5E-8 T 14-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 LH59_23740 242a727fa0eae7b79dd59f204193989e 368 PRINTS PR00184 Neisseria sp. porin signature 322 346 1.5E-8 T 14-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 LH59_23740 242a727fa0eae7b79dd59f204193989e 368 SUPERFAMILY SSF56935 21 368 2.85E-74 T 14-10-2018 LH59_23740 242a727fa0eae7b79dd59f204193989e 368 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 54 65 3.1E-6 T 14-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 LH59_23740 242a727fa0eae7b79dd59f204193989e 368 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 157 168 3.1E-6 T 14-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 LH59_23740 242a727fa0eae7b79dd59f204193989e 368 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 98 108 3.1E-6 T 14-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 LH59_23740 242a727fa0eae7b79dd59f204193989e 368 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 193 205 3.1E-6 T 14-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 LH59_23740 242a727fa0eae7b79dd59f204193989e 368 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 325 342 3.1E-6 T 14-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 LH59_23740 242a727fa0eae7b79dd59f204193989e 368 Gene3D G3DSA:2.40.160.10 10 368 4.3E-82 T 14-10-2018 IPR023614 Porin domain superfamily LH59_23740 242a727fa0eae7b79dd59f204193989e 368 Pfam PF13609 Gram-negative porin 7 345 5.6E-59 T 14-10-2018 LH59_23360 7871dd82c13c6e6b2f5a7c0421ec5bbf 684 Pfam PF07715 TonB-dependent Receptor Plug Domain 33 142 2.1E-19 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_23360 7871dd82c13c6e6b2f5a7c0421ec5bbf 684 Gene3D G3DSA:2.170.130.10 9 151 5.4E-22 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily LH59_23360 7871dd82c13c6e6b2f5a7c0421ec5bbf 684 Pfam PF00593 TonB dependent receptor 213 679 9.9E-46 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_23360 7871dd82c13c6e6b2f5a7c0421ec5bbf 684 Gene3D G3DSA:2.40.170.20 166 681 3.0E-96 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_23360 7871dd82c13c6e6b2f5a7c0421ec5bbf 684 SUPERFAMILY SSF56935 8 680 3.66E-117 T 14-10-2018 LH59_27685 4386160b4d417b0e5a2f53b2c4da89dc 242 SUPERFAMILY SSF46626 46 142 4.3E-18 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_27685 4386160b4d417b0e5a2f53b2c4da89dc 242 PIRSF PIRSF000005 10 242 3.0E-61 T 14-10-2018 IPR024167 Cytochrome c4-like GO:0005506|GO:0009055|GO:0020037|GO:0042597 LH59_27685 4386160b4d417b0e5a2f53b2c4da89dc 242 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 175 237 1.0E-6 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_27685 4386160b4d417b0e5a2f53b2c4da89dc 242 SUPERFAMILY SSF46626 156 240 4.73E-23 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_27685 4386160b4d417b0e5a2f53b2c4da89dc 242 Gene3D G3DSA:1.10.760.10 150 242 1.8E-24 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_27685 4386160b4d417b0e5a2f53b2c4da89dc 242 Gene3D G3DSA:1.10.760.10 44 142 6.8E-20 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_27685 4386160b4d417b0e5a2f53b2c4da89dc 242 PRINTS PR00605 Class IC cytochrome C signature 65 76 8.7E-5 T 14-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 LH59_27685 4386160b4d417b0e5a2f53b2c4da89dc 242 PRINTS PR00605 Class IC cytochrome C signature 216 238 8.7E-5 T 14-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 LH59_27685 4386160b4d417b0e5a2f53b2c4da89dc 242 Pfam PF00034 Cytochrome c 48 143 4.7E-10 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_04725 517695fd73c63f36895c149397bdad10 394 SUPERFAMILY SSF111369 55 264 7.72E-20 T 14-10-2018 LH59_04725 517695fd73c63f36895c149397bdad10 394 Gene3D G3DSA:2.40.50.100 62 224 2.3E-85 T 14-10-2018 LH59_04725 517695fd73c63f36895c149397bdad10 394 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 56 268 3.1E-11 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain LH59_04725 517695fd73c63f36895c149397bdad10 394 Gene3D G3DSA:2.40.30.170 51 320 2.3E-85 T 14-10-2018 LH59_04725 517695fd73c63f36895c149397bdad10 394 Gene3D G3DSA:1.10.287.470 96 187 2.3E-85 T 14-10-2018 LH59_04725 517695fd73c63f36895c149397bdad10 394 Gene3D G3DSA:2.40.420.20 46 381 2.3E-85 T 14-10-2018 LH59_04725 517695fd73c63f36895c149397bdad10 394 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 40 383 1.9E-44 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 LH59_04685 d280b04272f9719bc84851c899b4287c 304 Gene3D G3DSA:1.20.1090.10 114 304 1.2E-40 T 14-10-2018 LH59_04685 d280b04272f9719bc84851c899b4287c 304 Gene3D G3DSA:3.40.50.1970 1 112 6.3E-23 T 14-10-2018 LH59_04685 d280b04272f9719bc84851c899b4287c 304 Pfam PF00465 Iron-containing alcohol dehydrogenase 2 295 6.1E-58 T 14-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 LH59_04685 d280b04272f9719bc84851c899b4287c 304 SUPERFAMILY SSF56796 2 303 1.11E-59 T 14-10-2018 LH59_03715 a7a6edbf1d8c443dcee2ef8d1a763084 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.1E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_03715 a7a6edbf1d8c443dcee2ef8d1a763084 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.8E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_03715 a7a6edbf1d8c443dcee2ef8d1a763084 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.8E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_03715 a7a6edbf1d8c443dcee2ef8d1a763084 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.8E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_03715 a7a6edbf1d8c443dcee2ef8d1a763084 295 SUPERFAMILY SSF53850 90 292 1.55E-43 T 14-10-2018 LH59_03715 a7a6edbf1d8c443dcee2ef8d1a763084 295 Pfam PF03466 LysR substrate binding domain 88 289 1.7E-48 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_03715 a7a6edbf1d8c443dcee2ef8d1a763084 295 Gene3D G3DSA:3.40.190.290 90 293 4.9E-56 T 14-10-2018 LH59_03715 a7a6edbf1d8c443dcee2ef8d1a763084 295 Gene3D G3DSA:1.10.10.10 1 88 6.3E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_03715 a7a6edbf1d8c443dcee2ef8d1a763084 295 SUPERFAMILY SSF46785 1 111 1.95E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_19910 a504f326720d2259c71732e99fa29e1a 489 SUPERFAMILY SSF53720 12 486 2.88E-172 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 LH59_19910 a504f326720d2259c71732e99fa29e1a 489 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 287 298 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 LH59_19910 a504f326720d2259c71732e99fa29e1a 489 Pfam PF00171 Aldehyde dehydrogenase family 24 482 1.0E-172 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 LH59_19910 a504f326720d2259c71732e99fa29e1a 489 TIGRFAM TIGR01780 SSADH: succinate-semialdehyde dehydrogenase 35 481 1.2E-221 T 14-10-2018 IPR010102 Succinate semialdehyde dehydrogenase GO:0009013|GO:0009450|GO:0055114 Reactome: R-HSA-916853 LH59_19910 a504f326720d2259c71732e99fa29e1a 489 Gene3D G3DSA:3.40.605.10 24 478 2.5E-185 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 LH59_19910 a504f326720d2259c71732e99fa29e1a 489 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 259 266 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 LH59_19910 a504f326720d2259c71732e99fa29e1a 489 Gene3D G3DSA:3.40.309.10 266 455 2.5E-185 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 LH59_02030 90e73f9e1059c49834712ce7d2ef5264 141 SUPERFAMILY SSF46604 88 135 1.15E-7 T 14-10-2018 IPR036794 ATP synthase delta/epsilon subunit, C-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 LH59_02030 90e73f9e1059c49834712ce7d2ef5264 141 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 3 127 1.5E-40 T 14-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 LH59_02030 90e73f9e1059c49834712ce7d2ef5264 141 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 132 21.479 T 14-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 LH59_02030 90e73f9e1059c49834712ce7d2ef5264 141 SUPERFAMILY SSF51344 3 85 4.58E-25 T 14-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 LH59_02030 90e73f9e1059c49834712ce7d2ef5264 141 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 4 83 1.3E-29 T 14-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 LH59_02030 90e73f9e1059c49834712ce7d2ef5264 141 Gene3D G3DSA:2.60.15.10 2 89 1.5E-31 T 14-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 LH59_02030 90e73f9e1059c49834712ce7d2ef5264 141 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 9 84 7.0E-35 T 14-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 LH59_02030 90e73f9e1059c49834712ce7d2ef5264 141 Gene3D G3DSA:1.20.5.440 90 132 6.4E-6 T 14-10-2018 LH59_02655 6a509f52dea4ecdb799f5786f73f79fd 246 SUPERFAMILY SSF52540 5 240 8.24E-83 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_02655 6a509f52dea4ecdb799f5786f73f79fd 246 PIRSF PIRSF039085 2 246 6.3E-108 T 14-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 LH59_02655 6a509f52dea4ecdb799f5786f73f79fd 246 Gene3D G3DSA:3.40.50.300 3 246 4.7E-79 T 14-10-2018 LH59_02655 6a509f52dea4ecdb799f5786f73f79fd 246 SMART SM00382 30 218 6.3E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_02655 6a509f52dea4ecdb799f5786f73f79fd 246 Pfam PF00005 ABC transporter 21 169 1.9E-38 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_02655 6a509f52dea4ecdb799f5786f73f79fd 246 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_07475 cbfb7ed1c019ad225f0e2ada845ee149 309 PIRSF PIRSF020623 2 308 2.2E-109 T 14-10-2018 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 LH59_07475 cbfb7ed1c019ad225f0e2ada845ee149 309 Pfam PF08223 PaaX-like protein C-terminal domain 190 283 1.4E-29 T 14-10-2018 IPR013225 PaaX-like, C-terminal LH59_07475 cbfb7ed1c019ad225f0e2ada845ee149 309 Gene3D G3DSA:1.10.10.10 21 104 1.8E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_07475 cbfb7ed1c019ad225f0e2ada845ee149 309 TIGRFAM TIGR02277 PaaX_trns_reg: phenylacetic acid degradation operon negative regulatory protein PaaX 25 305 3.4E-110 T 14-10-2018 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 LH59_07475 cbfb7ed1c019ad225f0e2ada845ee149 309 Pfam PF07848 PaaX-like protein 22 91 2.2E-27 T 14-10-2018 IPR012906 PaaX-like, N-terminal LH59_07475 cbfb7ed1c019ad225f0e2ada845ee149 309 Gene3D G3DSA:3.30.70.2670 105 186 1.8E-27 T 14-10-2018 LH59_07475 cbfb7ed1c019ad225f0e2ada845ee149 309 Gene3D G3DSA:1.20.58.1460 20 267 1.8E-27 T 14-10-2018 LH59_16650 c32feb74ceb02809eeb843bbe9f7ff15 311 Pfam PF12697 Alpha/beta hydrolase family 38 304 5.9E-17 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_16650 c32feb74ceb02809eeb843bbe9f7ff15 311 Gene3D G3DSA:3.40.50.1820 9 310 4.5E-71 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_16650 c32feb74ceb02809eeb843bbe9f7ff15 311 SUPERFAMILY SSF53474 15 304 2.81E-41 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_16650 c32feb74ceb02809eeb843bbe9f7ff15 311 PRINTS PR00111 Alpha/beta hydrolase fold signature 107 120 1.2E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_16650 c32feb74ceb02809eeb843bbe9f7ff15 311 PRINTS PR00111 Alpha/beta hydrolase fold signature 61 76 1.2E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_11635 3d82db61921f849d1e5704f37cb2437f 868 SMART SM00471 433 580 4.4E-7 T 14-10-2018 IPR003607 HD/PDEase domain LH59_11635 3d82db61921f849d1e5704f37cb2437f 868 SUPERFAMILY SSF109604 406 528 1.1E-15 T 14-10-2018 LH59_11635 3d82db61921f849d1e5704f37cb2437f 868 PIRSF PIRSF006288 1 867 0.0 T 14-10-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 LH59_11635 3d82db61921f849d1e5704f37cb2437f 868 Pfam PF01842 ACT domain 793 837 7.3E-7 T 14-10-2018 IPR002912 ACT domain LH59_11635 3d82db61921f849d1e5704f37cb2437f 868 SUPERFAMILY SSF55021 672 729 5.41E-7 T 14-10-2018 LH59_11635 3d82db61921f849d1e5704f37cb2437f 868 Gene3D G3DSA:3.30.70.260 788 861 1.3E-7 T 14-10-2018 LH59_11635 3d82db61921f849d1e5704f37cb2437f 868 Pfam PF01909 Nucleotidyltransferase domain 53 116 7.2E-6 T 14-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 LH59_11635 3d82db61921f849d1e5704f37cb2437f 868 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 1 868 308.007 T 14-10-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 LH59_11635 3d82db61921f849d1e5704f37cb2437f 868 Pfam PF08335 GlnD PII-uridylyltransferase 162 300 2.1E-30 T 14-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 LH59_11635 3d82db61921f849d1e5704f37cb2437f 868 TIGRFAM TIGR01693 UTase_glnD: protein-P-II uridylyltransferase 19 858 1.9E-229 T 14-10-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 LH59_11635 3d82db61921f849d1e5704f37cb2437f 868 Pfam PF01966 HD domain 438 536 1.7E-8 T 14-10-2018 IPR006674 HD domain LH59_11635 3d82db61921f849d1e5704f37cb2437f 868 SUPERFAMILY SSF55021 789 859 1.48E-10 T 14-10-2018 LH59_11635 3d82db61921f849d1e5704f37cb2437f 868 SUPERFAMILY SSF81593 169 290 8.63E-9 T 14-10-2018 LH59_11635 3d82db61921f849d1e5704f37cb2437f 868 Gene3D G3DSA:1.10.3210.10 421 552 4.2E-10 T 14-10-2018 LH59_11635 3d82db61921f849d1e5704f37cb2437f 868 SUPERFAMILY SSF81301 35 154 3.27E-23 T 14-10-2018 LH59_15605 311eb66f35512d7d512123ab19dd72b2 426 ProSitePatterns PS00164 Enolase signature. 333 346 - T 14-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 LH59_15605 311eb66f35512d7d512123ab19dd72b2 426 SUPERFAMILY SSF51604 138 421 2.58E-116 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily LH59_15605 311eb66f35512d7d512123ab19dd72b2 426 SUPERFAMILY SSF54826 1 136 8.25E-49 T 14-10-2018 LH59_15605 311eb66f35512d7d512123ab19dd72b2 426 SMART SM01192 138 424 3.7E-191 T 14-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LH59_15605 311eb66f35512d7d512123ab19dd72b2 426 PRINTS PR00148 Enolase signature 36 50 5.1E-43 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LH59_15605 311eb66f35512d7d512123ab19dd72b2 426 PRINTS PR00148 Enolase signature 362 379 5.1E-43 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LH59_15605 311eb66f35512d7d512123ab19dd72b2 426 PRINTS PR00148 Enolase signature 106 122 5.1E-43 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LH59_15605 311eb66f35512d7d512123ab19dd72b2 426 PRINTS PR00148 Enolase signature 333 347 5.1E-43 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LH59_15605 311eb66f35512d7d512123ab19dd72b2 426 PRINTS PR00148 Enolase signature 160 173 5.1E-43 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LH59_15605 311eb66f35512d7d512123ab19dd72b2 426 PRINTS PR00148 Enolase signature 310 321 5.1E-43 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LH59_15605 311eb66f35512d7d512123ab19dd72b2 426 Pfam PF03952 Enolase, N-terminal domain 3 133 1.5E-50 T 14-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LH59_15605 311eb66f35512d7d512123ab19dd72b2 426 Gene3D G3DSA:3.30.390.10 1 126 6.1E-47 T 14-10-2018 IPR029017 Enolase-like, N-terminal LH59_15605 311eb66f35512d7d512123ab19dd72b2 426 Pfam PF00113 Enolase, C-terminal TIM barrel domain 139 422 8.3E-112 T 14-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LH59_15605 311eb66f35512d7d512123ab19dd72b2 426 SMART SM01193 3 133 9.3E-80 T 14-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LH59_15605 311eb66f35512d7d512123ab19dd72b2 426 Gene3D G3DSA:3.20.20.120 127 426 4.8E-121 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily LH59_15605 311eb66f35512d7d512123ab19dd72b2 426 Hamap MF_00318 Enolase [eno]. 1 410 41.448 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LH59_15605 311eb66f35512d7d512123ab19dd72b2 426 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 3 422 2.1E-184 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LH59_15605 311eb66f35512d7d512123ab19dd72b2 426 PIRSF PIRSF001400 1 423 3.2E-170 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 LH59_05175 1644a4b76b652eb33990c25c86818863 192 TIGRFAM TIGR01841 phasin: phasin family protein 27 112 8.6E-23 T 14-10-2018 IPR010127 Phasin, subfamily 1 LH59_05175 1644a4b76b652eb33990c25c86818863 192 Pfam PF09361 Phasin protein 7 105 1.4E-24 T 14-10-2018 IPR018968 Phasin LH59_01445 546e0e2c925be5d907aeffa7edfb5d7f 206 Gene3D G3DSA:2.60.120.10 15 117 1.1E-55 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_01445 546e0e2c925be5d907aeffa7edfb5d7f 206 SUPERFAMILY SSF51182 6 174 1.69E-53 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_01445 546e0e2c925be5d907aeffa7edfb5d7f 206 Gene3D G3DSA:2.60.120.10 10 175 1.1E-55 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_01445 546e0e2c925be5d907aeffa7edfb5d7f 206 Pfam PF05962 HutD 12 176 1.9E-51 T 14-10-2018 IPR010282 Uncharacterised protein family HutD/Ves LH59_11350 b137235a3a378fedb28c0410a70a727e 210 PIRSF PIRSF002884 1 210 3.4E-86 T 14-10-2018 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 LH59_11350 b137235a3a378fedb28c0410a70a727e 210 Pfam PF04344 Chemotaxis phosphatase, CheZ 14 210 9.0E-77 T 14-10-2018 IPR007439 Chemotaxis phosphatase, CheZ GO:0003824|GO:0009288|GO:0050920 LH59_11350 b137235a3a378fedb28c0410a70a727e 210 Gene3D G3DSA:1.20.5.590 7 32 1.1E-6 T 14-10-2018 LH59_11350 b137235a3a378fedb28c0410a70a727e 210 SUPERFAMILY SSF75708 10 209 2.48E-63 T 14-10-2018 LH59_11350 b137235a3a378fedb28c0410a70a727e 210 Gene3D G3DSA:1.10.287.500 33 166 9.2E-52 T 14-10-2018 LH59_24040 2b47d62486df89adc2140daa1c2525ce 340 Pfam PF01545 Cation efflux family 26 265 1.6E-34 T 14-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 LH59_24040 2b47d62486df89adc2140daa1c2525ce 340 Gene3D G3DSA:1.20.1510.10 195 265 7.0E-8 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily LH59_24040 2b47d62486df89adc2140daa1c2525ce 340 Gene3D G3DSA:1.20.1510.10 19 156 3.6E-19 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily LH59_24040 2b47d62486df89adc2140daa1c2525ce 340 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 19 334 1.4E-65 T 14-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 LH59_24040 2b47d62486df89adc2140daa1c2525ce 340 SUPERFAMILY SSF161111 16 266 2.09E-49 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily LH59_26630 fddd29b12b7ce32c0498e32de257a991 213 Pfam PF03968 OstA-like protein 52 169 3.7E-23 T 14-10-2018 IPR005653 Organic solvent tolerance-like, N-terminal LH59_26630 fddd29b12b7ce32c0498e32de257a991 213 TIGRFAM TIGR03002 outer_YhbN_LptA: lipopolysaccharide transport periplasmic protein LptA 49 192 8.5E-27 T 14-10-2018 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 LH59_26630 fddd29b12b7ce32c0498e32de257a991 213 Gene3D G3DSA:2.60.450.10 45 197 2.0E-31 T 14-10-2018 LH59_26630 fddd29b12b7ce32c0498e32de257a991 213 Hamap MF_01914 Lipopolysaccharide export system protein LptA [lptA]. 13 193 21.939 T 14-10-2018 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 LH59_25260 e27b2b6da45675ebab49962d4eaef68b 480 Pfam PF01425 Amidase 20 458 1.1E-72 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_25260 e27b2b6da45675ebab49962d4eaef68b 480 SUPERFAMILY SSF75304 1 468 9.68E-101 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_25260 e27b2b6da45675ebab49962d4eaef68b 480 Gene3D G3DSA:3.90.1300.10 1 476 1.4E-115 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_13705 14e0ac75b7258deea4d273c97fa53bf6 266 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 102 265 6.3E-7 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 LH59_13705 14e0ac75b7258deea4d273c97fa53bf6 266 Gene3D G3DSA:3.90.850.10 1 266 2.7E-80 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 LH59_13705 14e0ac75b7258deea4d273c97fa53bf6 266 TIGRFAM TIGR02312 HpaH: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase 2 266 7.3E-137 T 14-10-2018 IPR012690 2-oxo-hepta-4-ene-1,7-dioic acid hydratase GO:0018817|GO:0019439 LH59_13705 14e0ac75b7258deea4d273c97fa53bf6 266 SUPERFAMILY SSF56529 1 266 2.62E-76 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 LH59_12305 257752f35219f2bfd463501e9e1eba60 332 Gene3D G3DSA:3.40.190.10 22 119 7.3E-15 T 14-10-2018 LH59_12305 257752f35219f2bfd463501e9e1eba60 332 Gene3D G3DSA:3.40.190.10 127 322 9.8E-22 T 14-10-2018 LH59_12305 257752f35219f2bfd463501e9e1eba60 332 SUPERFAMILY SSF53850 26 247 1.58E-37 T 14-10-2018 LH59_12305 257752f35219f2bfd463501e9e1eba60 332 Pfam PF09084 NMT1/THI5 like 39 246 1.8E-24 T 14-10-2018 IPR015168 SsuA/THI5-like LH59_25245 831a21452095d6742f98f3bf73d910bb 232 Pfam PF13545 Crp-like helix-turn-helix domain 153 215 1.4E-13 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 LH59_25245 831a21452095d6742f98f3bf73d910bb 232 Gene3D G3DSA:2.60.120.10 1 136 4.6E-22 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_25245 831a21452095d6742f98f3bf73d910bb 232 SMART SM00419 161 209 1.3E-5 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 LH59_25245 831a21452095d6742f98f3bf73d910bb 232 Pfam PF00027 Cyclic nucleotide-binding domain 26 112 3.9E-15 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain LH59_25245 831a21452095d6742f98f3bf73d910bb 232 SUPERFAMILY SSF51206 5 132 2.75E-25 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like LH59_25245 831a21452095d6742f98f3bf73d910bb 232 Gene3D G3DSA:1.10.10.10 140 220 1.0E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_25245 831a21452095d6742f98f3bf73d910bb 232 SUPERFAMILY SSF46785 154 219 3.38E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_25245 831a21452095d6742f98f3bf73d910bb 232 SMART SM00100 7 128 1.2E-4 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain LH59_12665 39163f37d9794024f857066b97c10b0c 567 PIRSF PIRSF029745 6 567 1.4E-144 T 14-10-2018 IPR027282 Two partner secretion pathway transporter GO:0015031 LH59_12665 39163f37d9794024f857066b97c10b0c 567 Pfam PF08479 POTRA domain, ShlB-type 75 154 4.1E-18 T 14-10-2018 IPR013686 Polypeptide-transport-associated, ShlB-type LH59_12665 39163f37d9794024f857066b97c10b0c 567 Pfam PF03865 Haemolysin secretion/activation protein ShlB/FhaC/HecB 218 531 9.6E-107 T 14-10-2018 IPR005565 Haemolysin activator HlyB, C-terminal LH59_12665 39163f37d9794024f857066b97c10b0c 567 Pfam PF17287 POTRA domain 155 209 8.8E-18 T 14-10-2018 IPR035251 ShlB, POTRA domain LH59_12665 39163f37d9794024f857066b97c10b0c 567 Gene3D G3DSA:2.40.160.50 187 566 3.0E-95 T 14-10-2018 LH59_08800 96f85ab96544ad54a1d67758bd71f85e 487 SMART SM00316 37 118 1.5E-9 T 14-10-2018 IPR022967 RNA-binding domain, S1 LH59_08800 96f85ab96544ad54a1d67758bd71f85e 487 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 424 5.3E-152 T 14-10-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 LH59_08800 96f85ab96544ad54a1d67758bd71f85e 487 Gene3D G3DSA:2.40.50.140 31 124 1.3E-28 T 14-10-2018 LH59_08800 96f85ab96544ad54a1d67758bd71f85e 487 Pfam PF10150 Ribonuclease E/G family 120 391 1.1E-100 T 14-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 LH59_08800 96f85ab96544ad54a1d67758bd71f85e 487 SUPERFAMILY SSF50249 39 124 2.82E-17 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_08800 96f85ab96544ad54a1d67758bd71f85e 487 Gene3D G3DSA:3.40.1260.20 400 487 3.9E-5 T 14-10-2018 LH59_25095 333dcc04ed20845d1275fc7895dfd7e7 551 Hamap MF_00577 Urocanate hydratase [hutU]. 1 550 43.645 T 14-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 LH59_25095 333dcc04ed20845d1275fc7895dfd7e7 551 PIRSF PIRSF001423 1 550 1.2E-244 T 14-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 LH59_25095 333dcc04ed20845d1275fc7895dfd7e7 551 Gene3D G3DSA:3.40.1770.10 13 533 9.8E-219 T 14-10-2018 LH59_25095 333dcc04ed20845d1275fc7895dfd7e7 551 Pfam PF01175 Urocanase Rossmann-like domain 132 340 4.4E-77 T 14-10-2018 IPR035085 Urocanase, Rossmann-like domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 LH59_25095 333dcc04ed20845d1275fc7895dfd7e7 551 TIGRFAM TIGR01228 hutU: urocanate hydratase 4 542 7.7E-212 T 14-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 LH59_25095 333dcc04ed20845d1275fc7895dfd7e7 551 SUPERFAMILY SSF111326 2 542 2.62E-220 T 14-10-2018 IPR036190 Urocanase superfamily KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 LH59_25095 333dcc04ed20845d1275fc7895dfd7e7 551 Pfam PF17392 Urocanase C-terminal domain 343 536 7.5E-77 T 14-10-2018 IPR035401 Urocanase, C-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 LH59_25095 333dcc04ed20845d1275fc7895dfd7e7 551 Gene3D G3DSA:3.40.50.10730 133 340 9.8E-219 T 14-10-2018 IPR038364 Urocanase, central domain superfamily KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 LH59_25095 333dcc04ed20845d1275fc7895dfd7e7 551 Pfam PF17391 Urocanase N-terminal domain 9 129 2.4E-44 T 14-10-2018 IPR035400 Urocanase, N-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 LH59_28135 95374fa14d4e59e66dcf99a5424ec56c 344 PIRSF PIRSF038991 1 344 5.6E-83 T 14-10-2018 IPR007820 AbrB family GO:0010468|GO:0016021 LH59_28135 95374fa14d4e59e66dcf99a5424ec56c 344 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 9 160 2.4E-36 T 14-10-2018 IPR017516 AbrB duplication LH59_28135 95374fa14d4e59e66dcf99a5424ec56c 344 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 180 335 1.3E-34 T 14-10-2018 IPR017516 AbrB duplication LH59_28135 95374fa14d4e59e66dcf99a5424ec56c 344 Pfam PF05145 Transition state regulatory protein AbrB 28 336 6.2E-84 T 14-10-2018 IPR007820 AbrB family GO:0010468|GO:0016021 LH59_20805 2edfb338fed82acb862e9be489f0c151 142 Pfam PF03061 Thioesterase superfamily 49 122 2.5E-15 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 LH59_20805 2edfb338fed82acb862e9be489f0c151 142 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 36 116 3.8E-10 T 14-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 LH59_20805 2edfb338fed82acb862e9be489f0c151 142 SUPERFAMILY SSF54637 9 134 5.64E-26 T 14-10-2018 IPR029069 HotDog domain superfamily LH59_20805 2edfb338fed82acb862e9be489f0c151 142 Gene3D G3DSA:3.10.129.10 1 135 5.6E-41 T 14-10-2018 LH59_14335 dc61eef51bba5400e25b7e162c658c26 132 SUPERFAMILY SSF55298 8 129 1.01E-36 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 LH59_14335 dc61eef51bba5400e25b7e162c658c26 132 Gene3D G3DSA:3.30.1330.40 1 130 1.9E-41 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 LH59_14335 dc61eef51bba5400e25b7e162c658c26 132 Pfam PF01042 Endoribonuclease L-PSP 13 127 1.1E-27 T 14-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 LH59_04665 7ea032506bb12344b427524ed6628edd 140 Gene3D G3DSA:3.10.450.50 7 139 5.5E-16 T 14-10-2018 LH59_04665 7ea032506bb12344b427524ed6628edd 140 Pfam PF13577 SnoaL-like domain 8 129 3.1E-10 T 14-10-2018 IPR037401 SnoaL-like domain LH59_04665 7ea032506bb12344b427524ed6628edd 140 SUPERFAMILY SSF54427 9 131 3.91E-16 T 14-10-2018 IPR032710 NTF2-like domain superfamily LH59_10270 f4d4681d4eec65c3407669844b7f6975 413 SUPERFAMILY SSF51905 2 357 6.48E-23 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_10270 f4d4681d4eec65c3407669844b7f6975 413 Gene3D G3DSA:3.50.50.60 4 323 2.4E-128 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_10270 f4d4681d4eec65c3407669844b7f6975 413 Gene3D G3DSA:3.30.9.40 65 272 2.4E-128 T 14-10-2018 LH59_13020 a60461aec5ebbe364b91b44a676cb9a5 246 SUPERFAMILY SSF55781 76 242 3.86E-35 T 14-10-2018 LH59_13020 a60461aec5ebbe364b91b44a676cb9a5 246 Pfam PF09339 IclR helix-turn-helix domain 6 53 3.3E-9 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_13020 a60461aec5ebbe364b91b44a676cb9a5 246 Pfam PF01614 Bacterial transcriptional regulator 124 242 2.2E-17 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal LH59_13020 a60461aec5ebbe364b91b44a676cb9a5 246 SUPERFAMILY SSF46785 3 70 1.32E-10 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_13020 a60461aec5ebbe364b91b44a676cb9a5 246 Gene3D G3DSA:3.30.450.40 74 243 1.9E-36 T 14-10-2018 IPR029016 GAF-like domain superfamily LH59_13020 a60461aec5ebbe364b91b44a676cb9a5 246 Gene3D G3DSA:1.10.10.10 2 71 6.0E-13 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_07470 bdd159353eabd2e3c12d3f15c02461e8 208 SUPERFAMILY SSF64153 6 199 4.97E-50 T 14-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 LH59_07470 bdd159353eabd2e3c12d3f15c02461e8 208 Pfam PF03853 YjeF-related protein N-terminus 23 176 2.7E-36 T 14-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 LH59_07470 bdd159353eabd2e3c12d3f15c02461e8 208 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 2 200 21.329 T 14-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 LH59_07470 bdd159353eabd2e3c12d3f15c02461e8 208 Gene3D G3DSA:3.40.50.10260 2 202 6.9E-46 T 14-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 LH59_07470 bdd159353eabd2e3c12d3f15c02461e8 208 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 14 199 9.0E-28 T 14-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 LH59_19980 14697c91514a584abe8cad7bf787092d 317 Pfam PF01370 NAD dependent epimerase/dehydratase family 8 239 1.2E-77 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 LH59_19980 14697c91514a584abe8cad7bf787092d 317 Gene3D G3DSA:3.90.25.10 170 300 1.7E-103 T 14-10-2018 LH59_19980 14697c91514a584abe8cad7bf787092d 317 SUPERFAMILY SSF51735 5 308 8.81E-77 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_19980 14697c91514a584abe8cad7bf787092d 317 Hamap MF_00956 GDP-L-fucose synthase [fcl]. 5 307 47.527 T 14-10-2018 IPR028614 GDP-L-fucose synthase/GDP-L-colitose synthase GO:0009226|GO:0016491 KEGG: 00051+1.1.1.271|KEGG: 00520+1.1.1.271|MetaCyc: PWY-66|Reactome: R-HSA-6787639 LH59_19980 14697c91514a584abe8cad7bf787092d 317 Gene3D G3DSA:3.40.50.720 8 296 1.7E-103 T 14-10-2018 LH59_14990 802cb5c42a7d9c39feeed95b6a559cb0 232 SUPERFAMILY SSF52540 44 157 3.61E-30 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_14990 802cb5c42a7d9c39feeed95b6a559cb0 232 Gene3D G3DSA:3.40.50.300 44 156 1.6E-34 T 14-10-2018 LH59_14990 802cb5c42a7d9c39feeed95b6a559cb0 232 PIRSF PIRSF037290 1 229 6.3E-79 T 14-10-2018 IPR017166 Uncharacterised conserved protein UCP037290 LH59_25215 9e8ac5cdec8e688788e461dde7feac97 223 SUPERFAMILY SSF47616 87 216 5.08E-30 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily LH59_25215 9e8ac5cdec8e688788e461dde7feac97 223 Pfam PF02798 Glutathione S-transferase, N-terminal domain 6 79 3.4E-16 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 LH59_25215 9e8ac5cdec8e688788e461dde7feac97 223 Gene3D G3DSA:1.20.1050.10 94 217 1.9E-47 T 14-10-2018 LH59_25215 9e8ac5cdec8e688788e461dde7feac97 223 TIGRFAM TIGR01262 maiA: maleylacetoacetate isomerase 9 215 2.3E-80 T 14-10-2018 IPR005955 Glutathione S-transferases, class Zeta GO:0003824|GO:0005737|GO:0009072 Reactome: R-HSA-156590|Reactome: R-HSA-204174|Reactome: R-HSA-71182 LH59_25215 9e8ac5cdec8e688788e461dde7feac97 223 Gene3D G3DSA:3.40.30.10 5 93 1.9E-24 T 14-10-2018 LH59_25215 9e8ac5cdec8e688788e461dde7feac97 223 SUPERFAMILY SSF52833 7 95 7.04E-25 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_26820 503dc0f8631327ffbdc805badc3b5b0a 387 Pfam PF13458 Periplasmic binding protein 25 381 2.7E-70 T 14-10-2018 IPR028081 Leucine-binding protein domain LH59_26820 503dc0f8631327ffbdc805badc3b5b0a 387 SUPERFAMILY SSF53822 25 385 8.41E-88 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_26820 503dc0f8631327ffbdc805badc3b5b0a 387 Gene3D G3DSA:3.40.50.2300 151 279 5.1E-84 T 14-10-2018 LH59_26820 503dc0f8631327ffbdc805badc3b5b0a 387 Gene3D G3DSA:3.40.50.2300 27 353 5.1E-84 T 14-10-2018 LH59_26820 503dc0f8631327ffbdc805badc3b5b0a 387 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 48 64 6.9E-11 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 LH59_26820 503dc0f8631327ffbdc805badc3b5b0a 387 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 67 85 6.9E-11 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 LH59_26820 503dc0f8631327ffbdc805badc3b5b0a 387 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 285 298 6.9E-11 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 LH59_26820 503dc0f8631327ffbdc805badc3b5b0a 387 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 26 42 6.9E-11 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 LH59_02675 7415610e2c0ab054dcef4599254d5ded 230 SUPERFAMILY SSF52540 2 227 2.4E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_02675 7415610e2c0ab054dcef4599254d5ded 230 Gene3D G3DSA:3.40.50.300 1 230 1.5E-61 T 14-10-2018 LH59_02675 7415610e2c0ab054dcef4599254d5ded 230 SMART SM00382 26 207 1.9E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_02675 7415610e2c0ab054dcef4599254d5ded 230 Pfam PF00005 ABC transporter 19 158 1.8E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_02675 7415610e2c0ab054dcef4599254d5ded 230 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_24685 3d168fd02c7ac2d5caacf2c4d1ee8f05 377 Pfam PF00534 Glycosyl transferases group 1 197 352 8.3E-29 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 LH59_24685 3d168fd02c7ac2d5caacf2c4d1ee8f05 377 Gene3D G3DSA:3.40.50.2000 182 359 2.1E-55 T 14-10-2018 LH59_24685 3d168fd02c7ac2d5caacf2c4d1ee8f05 377 Pfam PF13477 Glycosyl transferase 4-like 6 156 2.9E-25 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 LH59_24685 3d168fd02c7ac2d5caacf2c4d1ee8f05 377 Gene3D G3DSA:3.40.50.2000 28 372 2.1E-55 T 14-10-2018 LH59_24685 3d168fd02c7ac2d5caacf2c4d1ee8f05 377 SUPERFAMILY SSF53756 25 375 1.35E-67 T 14-10-2018 LH59_05090 38d072bfbc8c057a94f136942f99bb26 507 SUPERFAMILY SSF48452 325 477 1.73E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_05090 38d072bfbc8c057a94f136942f99bb26 507 Gene3D G3DSA:3.30.2010.10 76 161 2.6E-7 T 14-10-2018 LH59_05090 38d072bfbc8c057a94f136942f99bb26 507 Pfam PF01435 Peptidase family M48 82 271 1.9E-33 T 14-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 LH59_05090 38d072bfbc8c057a94f136942f99bb26 507 Gene3D G3DSA:1.25.40.10 267 487 1.9E-10 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_06795 47354f72298164c1bfceb8d05d98a579 94 Gene3D G3DSA:3.30.70.100 1 94 4.4E-30 T 14-10-2018 LH59_06795 47354f72298164c1bfceb8d05d98a579 94 SUPERFAMILY SSF54909 1 94 3.16E-26 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel LH59_06795 47354f72298164c1bfceb8d05d98a579 94 Pfam PF07045 Domain of unknown function (DUF1330) 2 94 6.6E-33 T 14-10-2018 IPR010753 Domain of unknown function DUF1330 LH59_24280 4112f878a866bdae849ad7e2c6e59b5f 819 SUPERFAMILY SSF56935 122 819 2.88E-124 T 14-10-2018 LH59_24280 4112f878a866bdae849ad7e2c6e59b5f 819 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 168 819 6.4E-108 T 14-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 LH59_24280 4112f878a866bdae849ad7e2c6e59b5f 819 Gene3D G3DSA:2.40.170.20 277 819 2.8E-158 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_24280 4112f878a866bdae849ad7e2c6e59b5f 819 Pfam PF07715 TonB-dependent Receptor Plug Domain 166 269 9.3E-18 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_24280 4112f878a866bdae849ad7e2c6e59b5f 819 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 802 819 - T 14-10-2018 IPR010917 TonB-dependent receptor, conserved site LH59_24280 4112f878a866bdae849ad7e2c6e59b5f 819 Gene3D G3DSA:2.170.130.10 144 276 6.2E-43 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily LH59_24280 4112f878a866bdae849ad7e2c6e59b5f 819 Pfam PF07660 Secretin and TonB N terminus short domain 78 119 2.2E-7 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 LH59_24280 4112f878a866bdae849ad7e2c6e59b5f 819 Gene3D G3DSA:3.55.50.30 49 120 2.8E-24 T 14-10-2018 LH59_24280 4112f878a866bdae849ad7e2c6e59b5f 819 SMART SM00965 70 121 4.8E-9 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 LH59_24280 4112f878a866bdae849ad7e2c6e59b5f 819 Pfam PF00593 TonB dependent receptor 343 817 1.1E-47 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_25255 4312b4b2c5f5760a37155b2e832c47b1 233 SUPERFAMILY SSF89562 45 195 1.7E-41 T 14-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily LH59_25255 4312b4b2c5f5760a37155b2e832c47b1 233 Pfam PF03737 Aldolase/RraA 51 184 1.2E-40 T 14-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein LH59_25255 4312b4b2c5f5760a37155b2e832c47b1 233 Gene3D G3DSA:3.50.30.40 37 198 1.2E-46 T 14-10-2018 LH59_11170 d42625205910d1b15be3d03eb54edba4 232 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 130 158 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LH59_11170 d42625205910d1b15be3d03eb54edba4 232 Gene3D G3DSA:3.40.50.720 6 223 2.3E-50 T 14-10-2018 LH59_11170 d42625205910d1b15be3d03eb54edba4 232 SUPERFAMILY SSF51735 1 208 1.34E-48 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_11170 d42625205910d1b15be3d03eb54edba4 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 181 4.9E-18 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_11170 d42625205910d1b15be3d03eb54edba4 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 69 80 4.9E-18 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_11170 d42625205910d1b15be3d03eb54edba4 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 4.9E-18 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_11170 d42625205910d1b15be3d03eb54edba4 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 162 4.9E-18 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_11170 d42625205910d1b15be3d03eb54edba4 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 117 133 4.9E-18 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_11170 d42625205910d1b15be3d03eb54edba4 232 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 69 80 1.8E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_11170 d42625205910d1b15be3d03eb54edba4 232 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 162 1.8E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_11170 d42625205910d1b15be3d03eb54edba4 232 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 123 131 1.8E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_11170 d42625205910d1b15be3d03eb54edba4 232 Pfam PF00106 short chain dehydrogenase 7 185 1.4E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_02110 bec7a9aae98cbed7da98d3d49444dff3 305 Gene3D G3DSA:1.10.3720.10 92 302 2.9E-25 T 14-10-2018 IPR035906 MetI-like superfamily LH59_02110 bec7a9aae98cbed7da98d3d49444dff3 305 SUPERFAMILY SSF161098 99 292 1.57E-27 T 14-10-2018 IPR035906 MetI-like superfamily LH59_02110 bec7a9aae98cbed7da98d3d49444dff3 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 123 304 2.0E-32 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_02110 bec7a9aae98cbed7da98d3d49444dff3 305 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 25 67 2.1E-5 T 14-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain LH59_11235 721035a96badc47e585561d54a88fbfa 208 SUPERFAMILY SSF52172 9 158 5.27E-37 T 14-10-2018 IPR011006 CheY-like superfamily LH59_11235 721035a96badc47e585561d54a88fbfa 208 SMART SM00448 8 119 9.5E-31 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_11235 721035a96badc47e585561d54a88fbfa 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 146 160 2.3E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_11235 721035a96badc47e585561d54a88fbfa 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 176 2.3E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_11235 721035a96badc47e585561d54a88fbfa 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 188 2.3E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_11235 721035a96badc47e585561d54a88fbfa 208 SUPERFAMILY SSF46894 138 200 2.55E-17 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LH59_11235 721035a96badc47e585561d54a88fbfa 208 Gene3D G3DSA:3.40.50.2300 4 133 8.1E-50 T 14-10-2018 LH59_11235 721035a96badc47e585561d54a88fbfa 208 Pfam PF00196 Bacterial regulatory proteins, luxR family 145 199 5.5E-20 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_11235 721035a96badc47e585561d54a88fbfa 208 Pfam PF00072 Response regulator receiver domain 10 119 8.2E-30 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_11235 721035a96badc47e585561d54a88fbfa 208 SMART SM00421 143 200 2.3E-20 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_11235 721035a96badc47e585561d54a88fbfa 208 Gene3D G3DSA:1.10.10.10 134 203 6.8E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_11235 721035a96badc47e585561d54a88fbfa 208 ProSitePatterns PS00622 LuxR-type HTH domain signature. 160 187 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_24400 186078a3508dd8aeb07829015f7ed07c 163 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 24 155 3.0E-36 T 14-10-2018 IPR011605 NusB antitermination factor GO:0006353 LH59_24400 186078a3508dd8aeb07829015f7ed07c 163 Hamap MF_00073 Transcription antitermination protein NusB [nusB]. 22 157 20.244 T 14-10-2018 IPR011605 NusB antitermination factor GO:0006353 LH59_24400 186078a3508dd8aeb07829015f7ed07c 163 Pfam PF01029 NusB family 25 153 6.9E-29 T 14-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 LH59_24400 186078a3508dd8aeb07829015f7ed07c 163 Gene3D G3DSA:1.10.940.10 18 161 2.8E-40 T 14-10-2018 IPR035926 NusB-like superfamily LH59_24400 186078a3508dd8aeb07829015f7ed07c 163 SUPERFAMILY SSF48013 22 158 1.22E-35 T 14-10-2018 IPR035926 NusB-like superfamily LH59_27365 3eb229d76b8b363ee576b733beabe5b4 306 SUPERFAMILY SSF51735 16 272 7.3E-55 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_27365 3eb229d76b8b363ee576b733beabe5b4 306 Pfam PF01370 NAD dependent epimerase/dehydratase family 19 231 4.2E-33 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 LH59_27365 3eb229d76b8b363ee576b733beabe5b4 306 Gene3D G3DSA:3.40.50.720 6 288 4.0E-57 T 14-10-2018 LH59_18040 8d7ec4cf1afd0c388e7a787cacbda570 318 Gene3D G3DSA:3.40.50.720 23 309 1.6E-113 T 14-10-2018 LH59_18040 8d7ec4cf1afd0c388e7a787cacbda570 318 Gene3D G3DSA:3.40.50.720 104 289 1.6E-113 T 14-10-2018 LH59_18040 8d7ec4cf1afd0c388e7a787cacbda570 318 SUPERFAMILY SSF52283 6 136 1.42E-31 T 14-10-2018 LH59_18040 8d7ec4cf1afd0c388e7a787cacbda570 318 SUPERFAMILY SSF51735 104 287 1.36E-51 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_18040 8d7ec4cf1afd0c388e7a787cacbda570 318 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 152 179 - T 14-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 LH59_18040 8d7ec4cf1afd0c388e7a787cacbda570 318 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 113 286 1.1E-48 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 LH59_18040 8d7ec4cf1afd0c388e7a787cacbda570 318 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 17 317 5.1E-26 T 14-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 LH59_09075 23c8fc5615c4f89d397ed47f989d5e08 418 SUPERFAMILY SSF51905 1 413 2.98E-51 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_09075 23c8fc5615c4f89d397ed47f989d5e08 418 Gene3D G3DSA:3.50.50.60 3 63 3.6E-10 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_09075 23c8fc5615c4f89d397ed47f989d5e08 418 Gene3D G3DSA:3.30.9.10 134 367 4.2E-50 T 14-10-2018 LH59_09075 23c8fc5615c4f89d397ed47f989d5e08 418 Pfam PF01266 FAD dependent oxidoreductase 2 403 1.8E-66 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 LH59_09075 23c8fc5615c4f89d397ed47f989d5e08 418 SUPERFAMILY SSF54373 275 365 1.44E-15 T 14-10-2018 LH59_09075 23c8fc5615c4f89d397ed47f989d5e08 418 Gene3D G3DSA:3.50.50.60 107 410 4.2E-50 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_18370 342f5d18a5235945a070a4150802a8c1 409 Gene3D G3DSA:2.60.120.580 5 133 3.8E-16 T 14-10-2018 LH59_18370 342f5d18a5235945a070a4150802a8c1 409 Gene3D G3DSA:2.60.120.580 188 281 1.3E-20 T 14-10-2018 LH59_18370 342f5d18a5235945a070a4150802a8c1 409 SUPERFAMILY SSF141130 16 383 1.05E-77 T 14-10-2018 LH59_18370 342f5d18a5235945a070a4150802a8c1 409 Pfam PF03069 Acetamidase/Formamidase family 8 384 2.3E-175 T 14-10-2018 IPR004304 Acetamidase/Formamidase GO:0016811 LH59_26425 b71bf330575ba290c0c9a3bf9a70f701 459 SUPERFAMILY SSF116726 391 449 1.16E-9 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 LH59_26425 b71bf330575ba290c0c9a3bf9a70f701 459 Gene3D G3DSA:3.40.50.720 232 367 1.1E-37 T 14-10-2018 LH59_26425 b71bf330575ba290c0c9a3bf9a70f701 459 SUPERFAMILY SSF51735 232 377 4.6E-35 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_26425 b71bf330575ba290c0c9a3bf9a70f701 459 PRINTS PR00335 TrkA potassium uptake protein signature 49 59 1.9E-21 T 14-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 LH59_26425 b71bf330575ba290c0c9a3bf9a70f701 459 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 1.9E-21 T 14-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 LH59_26425 b71bf330575ba290c0c9a3bf9a70f701 459 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 1.9E-21 T 14-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 LH59_26425 b71bf330575ba290c0c9a3bf9a70f701 459 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 1.9E-21 T 14-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 LH59_26425 b71bf330575ba290c0c9a3bf9a70f701 459 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 1.9E-21 T 14-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 LH59_26425 b71bf330575ba290c0c9a3bf9a70f701 459 Gene3D G3DSA:3.30.70.1450 139 231 1.3E-15 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 LH59_26425 b71bf330575ba290c0c9a3bf9a70f701 459 SUPERFAMILY SSF51735 1 151 7.0E-33 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_26425 b71bf330575ba290c0c9a3bf9a70f701 459 Gene3D G3DSA:3.30.70.1450 368 459 2.6E-28 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 LH59_26425 b71bf330575ba290c0c9a3bf9a70f701 459 Gene3D G3DSA:3.40.50.720 2 138 3.8E-42 T 14-10-2018 LH59_26425 b71bf330575ba290c0c9a3bf9a70f701 459 SUPERFAMILY SSF116726 136 221 4.71E-8 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 LH59_26425 b71bf330575ba290c0c9a3bf9a70f701 459 Pfam PF02080 TrkA-C domain 154 221 4.3E-9 T 14-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 LH59_26425 b71bf330575ba290c0c9a3bf9a70f701 459 Pfam PF02080 TrkA-C domain 390 452 2.0E-12 T 14-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 LH59_26425 b71bf330575ba290c0c9a3bf9a70f701 459 Pfam PF02254 TrkA-N domain 3 124 8.6E-28 T 14-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 LH59_26425 b71bf330575ba290c0c9a3bf9a70f701 459 Pfam PF02254 TrkA-N domain 234 351 7.3E-25 T 14-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 LH59_11515 e2fe4aa536dfe7b6b22d854f78866b34 477 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 381 390 - T 14-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 LH59_11515 e2fe4aa536dfe7b6b22d854f78866b34 477 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 175 390 1.4E-69 T 14-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 LH59_11515 e2fe4aa536dfe7b6b22d854f78866b34 477 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 14 468 2.4E-174 T 14-10-2018 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 LH59_11515 e2fe4aa536dfe7b6b22d854f78866b34 477 SMART SM00382 187 374 2.1E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_11515 e2fe4aa536dfe7b6b22d854f78866b34 477 Gene3D G3DSA:3.40.50.12240 21 472 3.1E-152 T 14-10-2018 LH59_11515 e2fe4aa536dfe7b6b22d854f78866b34 477 TIGRFAM TIGR03496 FliI_clade1: flagellar protein export ATPase FliI 28 467 2.9E-192 T 14-10-2018 IPR020005 Flagellar export ATPase FliI, clade 1 GO:0016887|GO:0044780|GO:0071973 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 LH59_11515 e2fe4aa536dfe7b6b22d854f78866b34 477 SUPERFAMILY SSF52540 122 396 4.6E-92 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_18170 d49c17cf47d9dceba667e324dba8ea1c 221 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 71 4.2E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_18170 d49c17cf47d9dceba667e324dba8ea1c 221 SUPERFAMILY SSF46689 19 92 2.99E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_18170 d49c17cf47d9dceba667e324dba8ea1c 221 ProSitePatterns PS01081 TetR-type HTH domain signature. 38 68 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site LH59_18170 d49c17cf47d9dceba667e324dba8ea1c 221 Gene3D G3DSA:1.10.357.10 7 212 2.7E-14 T 14-10-2018 LH59_22910 4243c4dbf08bbea35cf0d3cd8e3ce814 358 SUPERFAMILY SSF53850 188 342 6.61E-12 T 14-10-2018 LH59_22910 4243c4dbf08bbea35cf0d3cd8e3ce814 358 Gene3D G3DSA:3.40.190.10 206 265 1.2E-5 T 14-10-2018 LH59_22910 4243c4dbf08bbea35cf0d3cd8e3ce814 358 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 28 86 7.5E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_22910 4243c4dbf08bbea35cf0d3cd8e3ce814 358 SUPERFAMILY SSF46785 25 142 9.07E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_22910 4243c4dbf08bbea35cf0d3cd8e3ce814 358 Pfam PF12727 PBP superfamily domain 147 327 2.5E-50 T 14-10-2018 IPR024370 PBP domain LH59_22910 4243c4dbf08bbea35cf0d3cd8e3ce814 358 Gene3D G3DSA:1.10.10.10 4 122 1.1E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_20040 5e3a8628e4ac55c1238c518493a3df3b 223 SUPERFAMILY SSF46689 4 77 4.67E-19 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_20040 5e3a8628e4ac55c1238c518493a3df3b 223 Gene3D G3DSA:1.10.357.10 10 219 3.3E-67 T 14-10-2018 LH59_20040 5e3a8628e4ac55c1238c518493a3df3b 223 SUPERFAMILY SSF48498 84 219 2.0E-33 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily LH59_20040 5e3a8628e4ac55c1238c518493a3df3b 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 3.2E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_20040 5e3a8628e4ac55c1238c518493a3df3b 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 3.2E-8 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_20040 5e3a8628e4ac55c1238c518493a3df3b 223 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 6.9E-15 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_13975 69ed986e06e751059c4f3b943dadcaac 118 SUPERFAMILY SSF81296 20 117 1.33E-26 T 14-10-2018 IPR014756 Immunoglobulin E-set LH59_13975 69ed986e06e751059c4f3b943dadcaac 118 Pfam PF04234 CopC domain 21 116 4.4E-25 T 14-10-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 LH59_13975 69ed986e06e751059c4f3b943dadcaac 118 Gene3D G3DSA:2.60.40.1220 20 117 3.1E-28 T 14-10-2018 LH59_14025 dd125897b1112c694cdb95230d22de57 373 SUPERFAMILY SSF53807 29 361 2.28E-49 T 14-10-2018 LH59_14025 dd125897b1112c694cdb95230d22de57 373 Pfam PF01497 Periplasmic binding protein 79 315 9.3E-23 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain LH59_14025 dd125897b1112c694cdb95230d22de57 373 Gene3D G3DSA:3.40.50.1980 26 370 3.2E-93 T 14-10-2018 LH59_22295 0f7c3ac7b9fddbac2851d9824e299738 338 Gene3D G3DSA:3.40.190.10 140 263 9.0E-101 T 14-10-2018 LH59_22295 0f7c3ac7b9fddbac2851d9824e299738 338 PIRSF PIRSF017082 10 337 2.3E-72 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_22295 0f7c3ac7b9fddbac2851d9824e299738 338 SUPERFAMILY SSF53850 131 298 5.84E-10 T 14-10-2018 LH59_22295 0f7c3ac7b9fddbac2851d9824e299738 338 Gene3D G3DSA:3.40.190.150 45 327 9.0E-101 T 14-10-2018 LH59_22295 0f7c3ac7b9fddbac2851d9824e299738 338 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 64 334 9.0E-74 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_22080 1971e5d93086e5609a6f4e8a5f1bd4d2 1190 Gene3D G3DSA:3.40.50.300 2 192 9.3E-27 T 14-10-2018 LH59_22080 1971e5d93086e5609a6f4e8a5f1bd4d2 1190 Gene3D G3DSA:3.40.50.300 353 495 1.5E-27 T 14-10-2018 LH59_22080 1971e5d93086e5609a6f4e8a5f1bd4d2 1190 Gene3D G3DSA:3.40.50.300 540 635 4.3E-12 T 14-10-2018 LH59_22080 1971e5d93086e5609a6f4e8a5f1bd4d2 1190 SUPERFAMILY SSF52540 10 928 2.99E-91 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_22080 1971e5d93086e5609a6f4e8a5f1bd4d2 1190 Pfam PF00580 UvrD/REP helicase N-terminal domain 14 462 2.7E-42 T 14-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 LH59_22080 1971e5d93086e5609a6f4e8a5f1bd4d2 1190 SUPERFAMILY SSF52980 1025 1174 1.45E-8 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 LH59_22080 1971e5d93086e5609a6f4e8a5f1bd4d2 1190 Gene3D G3DSA:3.90.320.10 1006 1188 7.9E-6 T 14-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal LH59_22080 1971e5d93086e5609a6f4e8a5f1bd4d2 1190 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1025 1179 4.0E-6 T 14-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type LH59_22080 1971e5d93086e5609a6f4e8a5f1bd4d2 1190 Gene3D G3DSA:3.40.50.300 808 944 1.7E-19 T 14-10-2018 LH59_22080 1971e5d93086e5609a6f4e8a5f1bd4d2 1190 Pfam PF13361 UvrD-like helicase C-terminal domain 825 923 2.8E-12 T 14-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 LH59_20860 fc2fa2d03f96df4fca1d3db0d4b5658f 218 SUPERFAMILY SSF46785 9 98 2.03E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_20860 fc2fa2d03f96df4fca1d3db0d4b5658f 218 SMART SM00345 15 73 3.7E-11 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_20860 fc2fa2d03f96df4fca1d3db0d4b5658f 218 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 73 4.3E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_20860 fc2fa2d03f96df4fca1d3db0d4b5658f 218 SUPERFAMILY SSF48008 79 212 2.88E-28 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_20860 fc2fa2d03f96df4fca1d3db0d4b5658f 218 Pfam PF07729 FCD domain 83 204 3.0E-29 T 14-10-2018 IPR011711 GntR, C-terminal LH59_20860 fc2fa2d03f96df4fca1d3db0d4b5658f 218 SMART SM00895 83 205 2.9E-23 T 14-10-2018 IPR011711 GntR, C-terminal LH59_20860 fc2fa2d03f96df4fca1d3db0d4b5658f 218 Gene3D G3DSA:1.20.120.530 77 217 6.2E-35 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_20860 fc2fa2d03f96df4fca1d3db0d4b5658f 218 Gene3D G3DSA:1.10.10.10 7 74 4.6E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_15650 963df1e79e1c2f705aa86b55a15805b0 377 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 108 1.5E-13 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 LH59_15650 963df1e79e1c2f705aa86b55a15805b0 377 Gene3D G3DSA:2.40.110.10 119 230 9.3E-26 T 14-10-2018 LH59_15650 963df1e79e1c2f705aa86b55a15805b0 377 Gene3D G3DSA:1.10.540.10 1 117 1.4E-22 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 LH59_15650 963df1e79e1c2f705aa86b55a15805b0 377 SUPERFAMILY SSF47203 227 371 9.18E-35 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 LH59_15650 963df1e79e1c2f705aa86b55a15805b0 377 Gene3D G3DSA:1.20.140.10 231 374 1.2E-31 T 14-10-2018 LH59_15650 963df1e79e1c2f705aa86b55a15805b0 377 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 120 213 5.4E-18 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 LH59_15650 963df1e79e1c2f705aa86b55a15805b0 377 SUPERFAMILY SSF56645 1 223 9.56E-49 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 LH59_15650 963df1e79e1c2f705aa86b55a15805b0 377 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 238 353 8.9E-23 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LH59_05085 844a91718c367d58d3d03f9802bc8ff3 281 Pfam PF00483 Nucleotidyl transferase 11 269 2.7E-30 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 LH59_05085 844a91718c367d58d3d03f9802bc8ff3 281 Gene3D G3DSA:3.90.550.10 1 278 7.9E-85 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases LH59_05085 844a91718c367d58d3d03f9802bc8ff3 281 SUPERFAMILY SSF53448 2 271 3.9E-67 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases LH59_05085 844a91718c367d58d3d03f9802bc8ff3 281 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 4 267 2.7E-108 T 14-10-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 LH59_12290 34d15e50e0487b653d3688ac01beff19 534 ProSitePatterns PS00211 ABC transporters family signature. 441 455 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_12290 34d15e50e0487b653d3688ac01beff19 534 SUPERFAMILY SSF52540 6 237 2.42E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_12290 34d15e50e0487b653d3688ac01beff19 534 Pfam PF00005 ABC transporter 18 184 1.0E-18 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_12290 34d15e50e0487b653d3688ac01beff19 534 SMART SM00382 26 238 2.9E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_12290 34d15e50e0487b653d3688ac01beff19 534 SMART SM00382 345 514 2.1E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_12290 34d15e50e0487b653d3688ac01beff19 534 SUPERFAMILY SSF52540 299 525 1.54E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_12290 34d15e50e0487b653d3688ac01beff19 534 Gene3D G3DSA:3.40.50.300 282 533 1.1E-52 T 14-10-2018 LH59_12290 34d15e50e0487b653d3688ac01beff19 534 Gene3D G3DSA:3.40.50.300 4 279 6.2E-58 T 14-10-2018 LH59_12290 34d15e50e0487b653d3688ac01beff19 534 Pfam PF12848 ABC transporter 224 311 5.9E-19 T 14-10-2018 IPR032781 ABC-transporter extension domain LH59_12290 34d15e50e0487b653d3688ac01beff19 534 Pfam PF00005 ABC transporter 337 469 1.9E-20 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_08255 0540faebb629020033fb0dcab106b3a4 170 SUPERFAMILY SSF55729 1 136 1.72E-20 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_08255 0540faebb629020033fb0dcab106b3a4 170 Gene3D G3DSA:3.40.630.30 1 165 8.7E-21 T 14-10-2018 LH59_08255 0540faebb629020033fb0dcab106b3a4 170 Pfam PF00583 Acetyltransferase (GNAT) family 48 132 2.4E-10 T 14-10-2018 IPR000182 GNAT domain LH59_12580 e985ad09ef3e9872981f1f4b6c8104ad 169 SUPERFAMILY SSF46785 22 148 5.08E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_12580 e985ad09ef3e9872981f1f4b6c8104ad 169 Gene3D G3DSA:1.10.10.10 21 158 7.5E-7 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_12580 e985ad09ef3e9872981f1f4b6c8104ad 169 PIRSF PIRSF036158 1 169 1.2E-76 T 14-10-2018 IPR014601 Transcriptional regulator with MarR-type HTH domain LH59_12580 e985ad09ef3e9872981f1f4b6c8104ad 169 Pfam PF13463 Winged helix DNA-binding domain 50 115 7.9E-19 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_01995 74fda38d25c2cb7619e7575c3d3fa90c 293 Pfam PF00119 ATP synthase A chain 43 286 5.6E-56 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 LH59_01995 74fda38d25c2cb7619e7575c3d3fa90c 293 ProSitePatterns PS00449 ATP synthase a subunit signature. 216 225 - T 14-10-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 LH59_01995 74fda38d25c2cb7619e7575c3d3fa90c 293 Hamap MF_01393 ATP synthase subunit a [atpB]. 32 293 14.135 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 LH59_01995 74fda38d25c2cb7619e7575c3d3fa90c 293 SUPERFAMILY SSF81336 96 286 5.62E-37 T 14-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 LH59_01995 74fda38d25c2cb7619e7575c3d3fa90c 293 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 33 288 5.3E-40 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 LH59_01995 74fda38d25c2cb7619e7575c3d3fa90c 293 Gene3D G3DSA:1.20.120.220 93 293 9.6E-50 T 14-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 LH59_20125 24f679b21c84cc7b0421a0da78f0fafd 297 Gene3D G3DSA:1.10.10.10 14 90 7.2E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_20125 24f679b21c84cc7b0421a0da78f0fafd 297 Pfam PF07702 UTRA domain 106 240 2.4E-30 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LH59_20125 24f679b21c84cc7b0421a0da78f0fafd 297 SMART SM00866 105 242 6.9E-28 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LH59_20125 24f679b21c84cc7b0421a0da78f0fafd 297 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 57 73 6.6E-10 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_20125 24f679b21c84cc7b0421a0da78f0fafd 297 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 57 6.6E-10 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_20125 24f679b21c84cc7b0421a0da78f0fafd 297 SUPERFAMILY SSF64288 71 247 3.14E-35 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily LH59_20125 24f679b21c84cc7b0421a0da78f0fafd 297 SMART SM00345 24 83 1.2E-15 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_20125 24f679b21c84cc7b0421a0da78f0fafd 297 Gene3D G3DSA:3.40.1410.10 91 249 7.2E-33 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily LH59_20125 24f679b21c84cc7b0421a0da78f0fafd 297 SUPERFAMILY SSF46785 13 95 7.75E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_20125 24f679b21c84cc7b0421a0da78f0fafd 297 Pfam PF00392 Bacterial regulatory proteins, gntR family 22 83 1.8E-16 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_04350 e9c3700aef41283f7d4a8134a88cc7bb 544 Gene3D G3DSA:3.40.30.120 390 531 2.0E-12 T 14-10-2018 LH59_04350 e9c3700aef41283f7d4a8134a88cc7bb 544 Gene3D G3DSA:3.30.70.2450 186 274 3.2E-84 T 14-10-2018 LH59_04350 e9c3700aef41283f7d4a8134a88cc7bb 544 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 30 3.1E-34 T 14-10-2018 LH59_04350 e9c3700aef41283f7d4a8134a88cc7bb 544 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 318 336 3.1E-34 T 14-10-2018 LH59_04350 e9c3700aef41283f7d4a8134a88cc7bb 544 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 157 172 3.1E-34 T 14-10-2018 LH59_04350 e9c3700aef41283f7d4a8134a88cc7bb 544 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 285 300 3.1E-34 T 14-10-2018 LH59_04350 e9c3700aef41283f7d4a8134a88cc7bb 544 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 300 316 3.1E-34 T 14-10-2018 LH59_04350 e9c3700aef41283f7d4a8134a88cc7bb 544 Gene3D G3DSA:3.50.50.60 9 347 3.2E-84 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_04350 e9c3700aef41283f7d4a8134a88cc7bb 544 Pfam PF01494 FAD binding domain 7 346 5.2E-58 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 LH59_04350 e9c3700aef41283f7d4a8134a88cc7bb 544 SUPERFAMILY SSF51905 7 377 9.43E-55 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_26415 728c263877cb986b98b55b5028d771c1 414 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 414 94.315 T 14-10-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 LH59_26415 728c263877cb986b98b55b5028d771c1 414 SUPERFAMILY SSF55931 5 367 2.75E-102 T 14-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 LH59_26415 728c263877cb986b98b55b5028d771c1 414 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 14 289 1.0E-53 T 14-10-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 LH59_26415 728c263877cb986b98b55b5028d771c1 414 Gene3D G3DSA:3.30.590.20 3 370 1.1E-98 T 14-10-2018 LH59_26415 728c263877cb986b98b55b5028d771c1 414 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 13 296 3.8E-91 T 14-10-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 LH59_19100 a85b4b155c4e26e3d00b1e05a3c39e4c 275 Pfam PF00905 Penicillin binding protein transpeptidase domain 30 264 2.8E-42 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 LH59_19100 a85b4b155c4e26e3d00b1e05a3c39e4c 275 SUPERFAMILY SSF56601 30 258 1.31E-35 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like LH59_19100 a85b4b155c4e26e3d00b1e05a3c39e4c 275 ProSitePatterns PS00337 Beta-lactamase class-D active site. 57 67 - T 14-10-2018 IPR002137 Beta-lactamase, class-D active site GO:0008800|GO:0017001 KEGG: 00311+3.5.2.6 LH59_19100 a85b4b155c4e26e3d00b1e05a3c39e4c 275 Gene3D G3DSA:3.40.710.10 27 273 3.3E-82 T 14-10-2018 LH59_02390 f33c1c83b99ff09f5efe59c849a0625d 415 Gene3D G3DSA:1.20.1250.20 9 203 2.5E-14 T 14-10-2018 LH59_02390 f33c1c83b99ff09f5efe59c849a0625d 415 SUPERFAMILY SSF103473 12 404 3.4E-37 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_02390 f33c1c83b99ff09f5efe59c849a0625d 415 Pfam PF07690 Major Facilitator Superfamily 17 365 8.7E-26 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_02390 f33c1c83b99ff09f5efe59c849a0625d 415 Gene3D G3DSA:1.20.1250.20 211 404 4.8E-13 T 14-10-2018 LH59_11345 3d6c751e9009d7779cb04c4d8dde6e99 129 SUPERFAMILY SSF52172 4 125 1.57E-36 T 14-10-2018 IPR011006 CheY-like superfamily LH59_11345 3d6c751e9009d7779cb04c4d8dde6e99 129 SMART SM00448 6 120 1.5E-37 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_11345 3d6c751e9009d7779cb04c4d8dde6e99 129 Gene3D G3DSA:3.40.50.2300 1 127 2.9E-38 T 14-10-2018 LH59_11345 3d6c751e9009d7779cb04c4d8dde6e99 129 Pfam PF00072 Response regulator receiver domain 8 120 1.3E-31 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_07995 2e2aa5925d9c08ff04fb10e5648bbc15 379 Pfam PF08442 ATP-grasp domain 2 201 1.5E-79 T 14-10-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 LH59_07995 2e2aa5925d9c08ff04fb10e5648bbc15 379 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 257 282 - T 14-10-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 LH59_07995 2e2aa5925d9c08ff04fb10e5648bbc15 379 PIRSF PIRSF001554 1 379 1.3E-152 T 14-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 LH59_07995 2e2aa5925d9c08ff04fb10e5648bbc15 379 Pfam PF00549 CoA-ligase 262 378 5.9E-25 T 14-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 LH59_07995 2e2aa5925d9c08ff04fb10e5648bbc15 379 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 378 1.6E-157 T 14-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 LH59_07995 2e2aa5925d9c08ff04fb10e5648bbc15 379 SUPERFAMILY SSF56059 1 238 7.25E-84 T 14-10-2018 LH59_07995 2e2aa5925d9c08ff04fb10e5648bbc15 379 Gene3D G3DSA:3.30.1490.20 21 104 7.7E-97 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 LH59_07995 2e2aa5925d9c08ff04fb10e5648bbc15 379 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 379 42.28 T 14-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 LH59_07995 2e2aa5925d9c08ff04fb10e5648bbc15 379 Gene3D G3DSA:3.30.470.20 1 234 7.7E-97 T 14-10-2018 LH59_07995 2e2aa5925d9c08ff04fb10e5648bbc15 379 SUPERFAMILY SSF52210 239 378 4.06E-53 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 LH59_07995 2e2aa5925d9c08ff04fb10e5648bbc15 379 Gene3D G3DSA:3.40.50.261 240 379 9.5E-57 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 LH59_09285 a032186ea0cfa3d6ff23d29ba19bbb12 279 SMART SM00858 51 115 9.1E-7 T 14-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 LH59_09285 a032186ea0cfa3d6ff23d29ba19bbb12 279 TIGRFAM TIGR03177 pilus_cpaB: Flp pilus assembly protein CpaB 18 246 3.0E-37 T 14-10-2018 IPR017592 Pilus assembly, Flp-type CpaB LH59_09285 a032186ea0cfa3d6ff23d29ba19bbb12 279 SUPERFAMILY SSF51269 54 111 6.91E-5 T 14-10-2018 IPR036732 Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily Reactome: R-HSA-4085001 LH59_09285 a032186ea0cfa3d6ff23d29ba19bbb12 279 Pfam PF08666 SAF domain 54 111 1.7E-7 T 14-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 LH59_09285 a032186ea0cfa3d6ff23d29ba19bbb12 279 Pfam PF16976 Flp pilus assembly protein RcpC/CpaB 125 219 8.5E-15 T 14-10-2018 IPR031571 Flp pilus assembly protein RcpC/CpaB domain LH59_27950 d30dfc2df2a0f351eb0b9df08938723b 369 Pfam PF01476 LysM domain 36 82 3.7E-7 T 14-10-2018 IPR018392 LysM domain LH59_27950 d30dfc2df2a0f351eb0b9df08938723b 369 Gene3D G3DSA:3.10.350.10 31 91 1.0E-6 T 14-10-2018 IPR036779 LysM domain superfamily LH59_27950 d30dfc2df2a0f351eb0b9df08938723b 369 PIRSF PIRSF029644 2 365 3.7E-104 T 14-10-2018 IPR016930 Uncharacterised conserved protein UCP029644, LysM, PA4035 LH59_27950 d30dfc2df2a0f351eb0b9df08938723b 369 Gene3D G3DSA:2.60.120.1440 119 249 2.6E-5 T 14-10-2018 LH59_27950 d30dfc2df2a0f351eb0b9df08938723b 369 Pfam PF04773 FecR protein 120 221 3.0E-16 T 14-10-2018 IPR006860 FecR protein LH59_27950 d30dfc2df2a0f351eb0b9df08938723b 369 SUPERFAMILY SSF54106 34 82 4.97E-6 T 14-10-2018 LH59_00545 a746ccc7a8361016194ec31e868b37a1 136 Gene3D G3DSA:3.30.720.120 9 71 5.6E-11 T 14-10-2018 LH59_00545 a746ccc7a8361016194ec31e868b37a1 136 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 14 128 5.9E-10 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain LH59_00545 a746ccc7a8361016194ec31e868b37a1 136 Gene3D G3DSA:3.30.720.110 78 135 3.2E-17 T 14-10-2018 LH59_00545 a746ccc7a8361016194ec31e868b37a1 136 SUPERFAMILY SSF54593 13 133 1.19E-25 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_23225 df53079f8249bd5f64b2c26fbcc16c0a 140 SUPERFAMILY SSF54593 6 126 4.95E-22 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_23225 df53079f8249bd5f64b2c26fbcc16c0a 140 Gene3D G3DSA:3.30.720.110 66 121 2.9E-25 T 14-10-2018 LH59_23225 df53079f8249bd5f64b2c26fbcc16c0a 140 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 115 1.8E-6 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain LH59_23225 df53079f8249bd5f64b2c26fbcc16c0a 140 Gene3D G3DSA:3.30.720.120 1 54 4.1E-25 T 14-10-2018 LH59_23225 df53079f8249bd5f64b2c26fbcc16c0a 140 PIRSF PIRSF039020 1 122 5.6E-46 T 14-10-2018 IPR026275 Glyoxalase/dioxygenase/EhpR LH59_11395 b114d309bc65ffd13d7df348d112c4d0 135 Pfam PF00460 Flagella basal body rod protein 19 39 1.9E-8 T 14-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 LH59_11395 b114d309bc65ffd13d7df348d112c4d0 135 TIGRFAM TIGR01396 FlgB: flagellar basal-body rod protein FlgB 6 134 2.3E-39 T 14-10-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 LH59_11395 b114d309bc65ffd13d7df348d112c4d0 135 PIRSF PIRSF002889 1 135 6.2E-44 T 14-10-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 LH59_15635 3c56140e9ae02c09448d41e6c0587cba 706 SUPERFAMILY SSF48179 482 625 3.57E-28 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 LH59_15635 3c56140e9ae02c09448d41e6c0587cba 706 SUPERFAMILY SSF48179 608 699 1.02E-21 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 LH59_15635 3c56140e9ae02c09448d41e6c0587cba 706 Gene3D G3DSA:3.90.226.10 6 299 9.5E-88 T 14-10-2018 LH59_15635 3c56140e9ae02c09448d41e6c0587cba 706 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 303 478 1.1E-58 T 14-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 LH59_15635 3c56140e9ae02c09448d41e6c0587cba 706 SUPERFAMILY SSF52096 10 292 1.11E-67 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily LH59_15635 3c56140e9ae02c09448d41e6c0587cba 706 SUPERFAMILY SSF51735 300 478 1.13E-52 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_15635 3c56140e9ae02c09448d41e6c0587cba 706 Gene3D G3DSA:3.40.50.720 300 485 1.3E-59 T 14-10-2018 LH59_15635 3c56140e9ae02c09448d41e6c0587cba 706 Gene3D G3DSA:1.10.1040.50 486 704 3.8E-73 T 14-10-2018 LH59_15635 3c56140e9ae02c09448d41e6c0587cba 706 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 97 117 - T 14-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 LH59_15635 3c56140e9ae02c09448d41e6c0587cba 706 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 614 697 1.9E-6 T 14-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 LH59_15635 3c56140e9ae02c09448d41e6c0587cba 706 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 483 576 4.8E-23 T 14-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 LH59_15635 3c56140e9ae02c09448d41e6c0587cba 706 Pfam PF00378 Enoyl-CoA hydratase/isomerase 16 196 1.6E-35 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 LH59_12990 f0d38519c622263b24ff2c13ef149be5 392 Pfam PF07995 Glucose / Sorbosone dehydrogenase 54 384 2.0E-142 T 14-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase LH59_12990 f0d38519c622263b24ff2c13ef149be5 392 Gene3D G3DSA:2.120.10.30 40 388 1.2E-139 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like LH59_12990 f0d38519c622263b24ff2c13ef149be5 392 SUPERFAMILY SSF50952 37 388 1.16E-50 T 14-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 LH59_14400 30ca4e2e1027b2fa641998b98b239152 329 SUPERFAMILY SSF53850 106 292 2.17E-14 T 14-10-2018 LH59_14400 30ca4e2e1027b2fa641998b98b239152 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 325 1.6E-80 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_14400 30ca4e2e1027b2fa641998b98b239152 329 PIRSF PIRSF017082 1 328 4.2E-74 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_14400 30ca4e2e1027b2fa641998b98b239152 329 Gene3D G3DSA:3.40.190.10 130 253 1.7E-109 T 14-10-2018 LH59_14400 30ca4e2e1027b2fa641998b98b239152 329 Gene3D G3DSA:3.40.190.150 33 319 1.7E-109 T 14-10-2018 LH59_09570 8a486439896ae4db6da17e6f07e804df 413 SUPERFAMILY SSF55031 213 329 1.15E-30 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain LH59_09570 8a486439896ae4db6da17e6f07e804df 413 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 10 406 2.0E-128 T 14-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 LH59_09570 8a486439896ae4db6da17e6f07e804df 413 SUPERFAMILY SSF53187 5 408 2.0E-91 T 14-10-2018 LH59_09570 8a486439896ae4db6da17e6f07e804df 413 Gene3D G3DSA:3.30.70.360 213 327 2.8E-151 T 14-10-2018 LH59_09570 8a486439896ae4db6da17e6f07e804df 413 Pfam PF07687 Peptidase dimerisation domain 210 312 2.8E-7 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain LH59_09570 8a486439896ae4db6da17e6f07e804df 413 Gene3D G3DSA:3.40.630.10 19 402 2.8E-151 T 14-10-2018 LH59_09570 8a486439896ae4db6da17e6f07e804df 413 PIRSF PIRSF001235 4 413 2.7E-133 T 14-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 LH59_09570 8a486439896ae4db6da17e6f07e804df 413 Pfam PF01546 Peptidase family M20/M25/M40 80 405 2.0E-38 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 LH59_17105 aac5c20764b7dfaeff605f1e1c89bee1 275 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 36 263 2.1E-53 T 14-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 LH59_17105 aac5c20764b7dfaeff605f1e1c89bee1 275 PIRSF PIRSF004848 29 269 1.0E-66 T 14-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 LH59_17105 aac5c20764b7dfaeff605f1e1c89bee1 275 SUPERFAMILY SSF51419 31 261 2.88E-73 T 14-10-2018 IPR029066 PLP-binding barrel LH59_17105 aac5c20764b7dfaeff605f1e1c89bee1 275 Pfam PF01168 Alanine racemase, N-terminal domain 36 263 5.1E-23 T 14-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LH59_17105 aac5c20764b7dfaeff605f1e1c89bee1 275 Hamap MF_02087 Pyridoxal phosphate homeostasis protein. 39 262 28.577 T 14-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 LH59_17105 aac5c20764b7dfaeff605f1e1c89bee1 275 Gene3D G3DSA:3.20.20.10 20 274 3.6E-84 T 14-10-2018 IPR029066 PLP-binding barrel LH59_05280 888d0e66d31d63040557af00ec9e5561 553 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 545 2.7E-157 T 14-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 LH59_05280 888d0e66d31d63040557af00ec9e5561 553 SUPERFAMILY SSF52540 1 215 2.98E-66 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_05280 888d0e66d31d63040557af00ec9e5561 553 Gene3D G3DSA:3.40.50.300 276 547 2.7E-54 T 14-10-2018 LH59_05280 888d0e66d31d63040557af00ec9e5561 553 Gene3D G3DSA:3.40.50.300 1 275 1.3E-48 T 14-10-2018 LH59_05280 888d0e66d31d63040557af00ec9e5561 553 PIRSF PIRSF003128 1 548 2.1E-161 T 14-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 LH59_05280 888d0e66d31d63040557af00ec9e5561 553 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 503 1.7E-19 T 14-10-2018 IPR003395 RecF/RecN/SMC, N-terminal LH59_05280 888d0e66d31d63040557af00ec9e5561 553 SUPERFAMILY SSF52540 3 497 7.56E-27 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_12020 e4accb453d573a595f05bfcc8a678dda 238 SUPERFAMILY SSF46894 150 236 1.47E-10 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LH59_12020 e4accb453d573a595f05bfcc8a678dda 238 Gene3D G3DSA:1.10.10.10 134 237 5.8E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_12020 e4accb453d573a595f05bfcc8a678dda 238 Pfam PF00486 Transcriptional regulatory protein, C terminal 161 234 1.2E-4 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_12020 e4accb453d573a595f05bfcc8a678dda 238 SUPERFAMILY SSF52172 15 123 2.49E-6 T 14-10-2018 IPR011006 CheY-like superfamily LH59_10940 632fbb9391813103a05e3401670fe1d6 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 64 9.2E-19 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_10940 632fbb9391813103a05e3401670fe1d6 304 SUPERFAMILY SSF46785 7 89 1.09E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_10940 632fbb9391813103a05e3401670fe1d6 304 Gene3D G3DSA:3.40.190.290 93 299 2.0E-29 T 14-10-2018 LH59_10940 632fbb9391813103a05e3401670fe1d6 304 Gene3D G3DSA:1.10.10.10 4 92 1.7E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_10940 632fbb9391813103a05e3401670fe1d6 304 SUPERFAMILY SSF53850 93 300 5.12E-33 T 14-10-2018 LH59_10940 632fbb9391813103a05e3401670fe1d6 304 Pfam PF03466 LysR substrate binding domain 92 298 6.4E-37 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_18580 a150882dfa8d9853d72d828fa8fd0b71 330 SUPERFAMILY SSF46689 222 271 3.14E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_18580 a150882dfa8d9853d72d828fa8fd0b71 330 Gene3D G3DSA:1.10.10.60 221 327 1.3E-32 T 14-10-2018 LH59_18580 a150882dfa8d9853d72d828fa8fd0b71 330 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 274 318 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 LH59_18580 a150882dfa8d9853d72d828fa8fd0b71 330 SMART SM00342 237 322 1.5E-20 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_18580 a150882dfa8d9853d72d828fa8fd0b71 330 Pfam PF14525 AraC-binding-like domain 24 200 3.4E-28 T 14-10-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like LH59_18580 a150882dfa8d9853d72d828fa8fd0b71 330 Pfam PF12833 Helix-turn-helix domain 243 324 1.2E-21 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_06070 a39a9fb5dd50b8acba4f3f0186f94533 324 Gene3D G3DSA:3.40.50.10330 16 145 1.6E-23 T 14-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 LH59_06070 a39a9fb5dd50b8acba4f3f0186f94533 324 Pfam PF00781 Diacylglycerol kinase catalytic domain 21 143 6.4E-22 T 14-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 LH59_06070 a39a9fb5dd50b8acba4f3f0186f94533 324 Gene3D G3DSA:2.60.200.40 146 307 1.9E-21 T 14-10-2018 LH59_06070 a39a9fb5dd50b8acba4f3f0186f94533 324 SUPERFAMILY SSF111331 20 315 1.36E-53 T 14-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily LH59_06000 07399ea493e86e76bf295e2c75715dd0 366 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 45 355 4.5E-63 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 LH59_06000 07399ea493e86e76bf295e2c75715dd0 366 SUPERFAMILY SSF111369 47 274 2.88E-16 T 14-10-2018 LH59_06000 07399ea493e86e76bf295e2c75715dd0 366 Gene3D G3DSA:2.40.50.100 56 202 1.8E-65 T 14-10-2018 LH59_06000 07399ea493e86e76bf295e2c75715dd0 366 Gene3D G3DSA:2.40.30.170 47 278 1.8E-65 T 14-10-2018 LH59_06000 07399ea493e86e76bf295e2c75715dd0 366 Gene3D G3DSA:2.40.420.20 279 353 1.8E-65 T 14-10-2018 LH59_06000 07399ea493e86e76bf295e2c75715dd0 366 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 57 271 2.6E-22 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain LH59_06000 07399ea493e86e76bf295e2c75715dd0 366 Gene3D G3DSA:1.10.287.470 90 163 1.8E-65 T 14-10-2018 LH59_07320 ff6d356fb63beb533a029aeca202a619 329 Pfam PF01370 NAD dependent epimerase/dehydratase family 2 240 5.6E-42 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 LH59_07320 ff6d356fb63beb533a029aeca202a619 329 TIGRFAM TIGR02197 heptose_epim: ADP-glyceromanno-heptose 6-epimerase 2 325 2.3E-127 T 14-10-2018 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 LH59_07320 ff6d356fb63beb533a029aeca202a619 329 SUPERFAMILY SSF51735 2 327 8.11E-58 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_07320 ff6d356fb63beb533a029aeca202a619 329 Hamap MF_01601 ADP-L-glycero-D-manno-heptose-6-epimerase [hldD]. 1 328 49.566 T 14-10-2018 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 LH59_07320 ff6d356fb63beb533a029aeca202a619 329 Gene3D G3DSA:3.40.50.720 3 322 2.2E-122 T 14-10-2018 LH59_07320 ff6d356fb63beb533a029aeca202a619 329 Gene3D G3DSA:3.90.25.10 166 309 2.2E-122 T 14-10-2018 LH59_20615 ee06e213efe70be0af5895fec50c354b 208 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 7 200 6.7E-53 T 14-10-2018 IPR006070 YrdC-like domain GO:0003725 LH59_20615 ee06e213efe70be0af5895fec50c354b 208 Pfam PF01300 Telomere recombination 23 198 1.9E-39 T 14-10-2018 IPR006070 YrdC-like domain GO:0003725 LH59_20615 ee06e213efe70be0af5895fec50c354b 208 Gene3D G3DSA:3.90.870.10 2 204 7.2E-57 T 14-10-2018 LH59_20615 ee06e213efe70be0af5895fec50c354b 208 SUPERFAMILY SSF55821 1 202 1.62E-57 T 14-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily LH59_11450 0e9070be682878c4341971d278fff34e 621 Pfam PF02203 Tar ligand binding domain homologue 1 168 1.0E-15 T 14-10-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 LH59_11450 0e9070be682878c4341971d278fff34e 621 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 393 422 1.1E-66 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_11450 0e9070be682878c4341971d278fff34e 621 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 5 30 1.1E-66 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_11450 0e9070be682878c4341971d278fff34e 621 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 364 391 1.1E-66 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_11450 0e9070be682878c4341971d278fff34e 621 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 287 316 1.1E-66 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_11450 0e9070be682878c4341971d278fff34e 621 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 188 208 1.1E-66 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_11450 0e9070be682878c4341971d278fff34e 621 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 441 470 1.1E-66 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_11450 0e9070be682878c4341971d278fff34e 621 Gene3D G3DSA:1.10.287.950 213 515 1.9E-95 T 14-10-2018 LH59_11450 0e9070be682878c4341971d278fff34e 621 SMART SM00304 213 265 2.6E-13 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_11450 0e9070be682878c4341971d278fff34e 621 Pfam PF00672 HAMP domain 213 261 1.7E-9 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_11450 0e9070be682878c4341971d278fff34e 621 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 325 481 9.3E-56 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 LH59_11450 0e9070be682878c4341971d278fff34e 621 SUPERFAMILY SSF58104 233 518 6.28E-78 T 14-10-2018 LH59_11450 0e9070be682878c4341971d278fff34e 621 SUPERFAMILY SSF47170 25 177 3.53E-16 T 14-10-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain superfamily LH59_11450 0e9070be682878c4341971d278fff34e 621 SMART SM00283 266 513 4.7E-98 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 LH59_05365 fff98c48dc93a367c83dbd39c85424aa 120 Gene3D G3DSA:1.10.760.10 22 116 6.0E-24 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_05365 fff98c48dc93a367c83dbd39c85424aa 120 PRINTS PR00605 Class IC cytochrome C signature 35 46 6.6E-5 T 14-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 LH59_05365 fff98c48dc93a367c83dbd39c85424aa 120 PRINTS PR00605 Class IC cytochrome C signature 87 109 6.6E-5 T 14-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 LH59_05365 fff98c48dc93a367c83dbd39c85424aa 120 Pfam PF00034 Cytochrome c 27 112 1.3E-13 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_05365 fff98c48dc93a367c83dbd39c85424aa 120 SUPERFAMILY SSF46626 4 114 1.67E-24 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_08835 55f6e741770bee669f7b3fe1b0e99ae9 602 PIRSF PIRSF036431 1 601 1.6E-180 T 14-10-2018 IPR017055 Signal transduction histidine kinase, DctB (C4-dicarboxylate transport system regulator) LH59_08835 55f6e741770bee669f7b3fe1b0e99ae9 602 PRINTS PR00344 Bacterial sensor protein C-terminal signature 548 566 1.5E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_08835 55f6e741770bee669f7b3fe1b0e99ae9 602 PRINTS PR00344 Bacterial sensor protein C-terminal signature 519 533 1.5E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_08835 55f6e741770bee669f7b3fe1b0e99ae9 602 PRINTS PR00344 Bacterial sensor protein C-terminal signature 537 547 1.5E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_08835 55f6e741770bee669f7b3fe1b0e99ae9 602 SMART SM00388 370 438 2.4E-10 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_08835 55f6e741770bee669f7b3fe1b0e99ae9 602 Gene3D G3DSA:3.30.450.20 161 277 7.8E-33 T 14-10-2018 LH59_08835 55f6e741770bee669f7b3fe1b0e99ae9 602 SUPERFAMILY SSF47384 355 434 2.55E-11 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 LH59_08835 55f6e741770bee669f7b3fe1b0e99ae9 602 Gene3D G3DSA:3.30.450.20 37 158 1.2E-34 T 14-10-2018 LH59_08835 55f6e741770bee669f7b3fe1b0e99ae9 602 SMART SM00387 480 598 1.3E-25 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_08835 55f6e741770bee669f7b3fe1b0e99ae9 602 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 481 596 2.0E-15 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_08835 55f6e741770bee669f7b3fe1b0e99ae9 602 Gene3D G3DSA:1.10.287.130 346 433 1.1E-21 T 14-10-2018 LH59_08835 55f6e741770bee669f7b3fe1b0e99ae9 602 SUPERFAMILY SSF55874 430 594 1.7E-29 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_08835 55f6e741770bee669f7b3fe1b0e99ae9 602 SUPERFAMILY SSF103190 61 169 1.02E-15 T 14-10-2018 IPR029151 Periplasmic sensor-like domain superfamily LH59_08835 55f6e741770bee669f7b3fe1b0e99ae9 602 Gene3D G3DSA:3.30.565.10 440 598 1.6E-30 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_08835 55f6e741770bee669f7b3fe1b0e99ae9 602 Pfam PF00512 His Kinase A (phospho-acceptor) domain 371 435 3.9E-12 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_05265 8883cceae23c54b226dbe3bdbdf84e0a 263 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 147 164 - T 14-10-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LH59_05265 8883cceae23c54b226dbe3bdbdf84e0a 263 PIRSF PIRSF000161 1 263 2.5E-84 T 14-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LH59_05265 8883cceae23c54b226dbe3bdbdf84e0a 263 Gene3D G3DSA:3.40.50.720 2 260 1.2E-96 T 14-10-2018 LH59_05265 8883cceae23c54b226dbe3bdbdf84e0a 263 SUPERFAMILY SSF51735 1 263 1.21E-45 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_05265 8883cceae23c54b226dbe3bdbdf84e0a 263 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 1 122 8.8E-37 T 14-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LH59_05265 8883cceae23c54b226dbe3bdbdf84e0a 263 SUPERFAMILY SSF55347 124 233 2.4E-35 T 14-10-2018 LH59_05265 8883cceae23c54b226dbe3bdbdf84e0a 263 Gene3D G3DSA:3.30.360.10 124 231 1.2E-96 T 14-10-2018 LH59_05265 8883cceae23c54b226dbe3bdbdf84e0a 263 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 125 261 6.0E-41 T 14-10-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LH59_05265 8883cceae23c54b226dbe3bdbdf84e0a 263 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 1 262 1.5E-88 T 14-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LH59_05265 8883cceae23c54b226dbe3bdbdf84e0a 263 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 1 262 33.789 T 14-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LH59_25555 621d8b89719e099785ff79781a8df24a 311 Gene3D G3DSA:3.20.20.70 2 311 7.2E-129 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_25555 621d8b89719e099785ff79781a8df24a 311 Pfam PF05853 beta-keto acid cleavage enzyme 7 303 4.6E-107 T 14-10-2018 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00310+2.3.1.247 LH59_25995 844c3de57ffaad7838e467c7ae5a6af4 403 Gene3D G3DSA:3.40.50.2300 41 357 7.7E-65 T 14-10-2018 LH59_25995 844c3de57ffaad7838e467c7ae5a6af4 403 SUPERFAMILY SSF53822 32 385 7.3E-67 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_25995 844c3de57ffaad7838e467c7ae5a6af4 403 Pfam PF13458 Periplasmic binding protein 33 377 6.5E-59 T 14-10-2018 IPR028081 Leucine-binding protein domain LH59_25995 844c3de57ffaad7838e467c7ae5a6af4 403 Gene3D G3DSA:3.40.50.2300 153 287 7.7E-65 T 14-10-2018 LH59_20885 e80b36aa7ddaa424603a5dd28c9aaa2c 178 Pfam PF00578 AhpC/TSA family 34 154 3.2E-14 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 LH59_20885 e80b36aa7ddaa424603a5dd28c9aaa2c 178 Gene3D G3DSA:3.40.30.10 23 178 3.2E-52 T 14-10-2018 LH59_20885 e80b36aa7ddaa424603a5dd28c9aaa2c 178 SUPERFAMILY SSF52833 34 173 2.84E-40 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_21505 7177f5720530aac66357da0221118a2e 404 Gene3D G3DSA:1.20.1250.20 12 386 5.9E-46 T 14-10-2018 LH59_21505 7177f5720530aac66357da0221118a2e 404 Pfam PF07690 Major Facilitator Superfamily 21 326 3.5E-28 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_21505 7177f5720530aac66357da0221118a2e 404 SUPERFAMILY SSF103473 10 388 1.57E-49 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_17670 f8bfbdedf6ccff09fe1bbd80d2b84186 402 Pfam PF01610 Transposase 292 401 3.9E-8 T 14-10-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain LH59_17670 f8bfbdedf6ccff09fe1bbd80d2b84186 402 Pfam PF00487 Fatty acid desaturase 17 219 2.0E-11 T 14-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 LH59_19660 a4a171da3489470a735090897cf0c2ca 255 SUPERFAMILY SSF51735 6 254 4.35E-76 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_19660 a4a171da3489470a735090897cf0c2ca 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 252 4.1E-61 T 14-10-2018 LH59_19660 a4a171da3489470a735090897cf0c2ca 255 Gene3D G3DSA:3.40.50.720 1 255 1.7E-77 T 14-10-2018 LH59_19660 a4a171da3489470a735090897cf0c2ca 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 2.0E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_19660 a4a171da3489470a735090897cf0c2ca 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 2.0E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_19660 a4a171da3489470a735090897cf0c2ca 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 2.0E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_19660 a4a171da3489470a735090897cf0c2ca 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 181 2.0E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_19660 a4a171da3489470a735090897cf0c2ca 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 2.0E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_19660 a4a171da3489470a735090897cf0c2ca 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.0E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_19660 a4a171da3489470a735090897cf0c2ca 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 149 177 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LH59_19660 a4a171da3489470a735090897cf0c2ca 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 181 4.2E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_19660 a4a171da3489470a735090897cf0c2ca 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 4.2E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_19660 a4a171da3489470a735090897cf0c2ca 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 4.2E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_04190 e1b7ca57970e15fa3d937914ead9953f 217 Gene3D G3DSA:1.10.3720.10 2 217 2.3E-52 T 14-10-2018 IPR035906 MetI-like superfamily LH59_04190 e1b7ca57970e15fa3d937914ead9953f 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 31 214 2.5E-23 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_04190 e1b7ca57970e15fa3d937914ead9953f 217 SUPERFAMILY SSF161098 8 207 2.09E-46 T 14-10-2018 IPR035906 MetI-like superfamily LH59_15040 99f6864d630538c75c2b7eaa3362fe9a 183 Pfam PF01292 Prokaryotic cytochrome b561 10 181 5.5E-24 T 14-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 LH59_15040 99f6864d630538c75c2b7eaa3362fe9a 183 SUPERFAMILY SSF81342 8 183 7.45E-34 T 14-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 LH59_02770 cf21917e5680ac5d5e20a9ee3d54642d 134 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 45 57 1.8E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_02770 cf21917e5680ac5d5e20a9ee3d54642d 134 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 29 45 1.8E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_02770 cf21917e5680ac5d5e20a9ee3d54642d 134 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 15 29 1.8E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_02770 cf21917e5680ac5d5e20a9ee3d54642d 134 ProSitePatterns PS00622 LuxR-type HTH domain signature. 29 56 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_02770 cf21917e5680ac5d5e20a9ee3d54642d 134 SMART SM00421 12 69 1.2E-19 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_02770 cf21917e5680ac5d5e20a9ee3d54642d 134 Pfam PF00196 Bacterial regulatory proteins, luxR family 14 67 4.4E-18 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_02770 cf21917e5680ac5d5e20a9ee3d54642d 134 Gene3D G3DSA:1.10.10.10 10 71 2.4E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_02770 cf21917e5680ac5d5e20a9ee3d54642d 134 SUPERFAMILY SSF46894 5 69 5.1E-19 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LH59_13055 9fd0838f970b10034712e6538687ac04 380 SUPERFAMILY SSF51395 4 374 1.28E-91 T 14-10-2018 LH59_13055 9fd0838f970b10034712e6538687ac04 380 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 276 282 - T 14-10-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 Reactome: R-HSA-9033241 LH59_13055 9fd0838f970b10034712e6538687ac04 380 Pfam PF01070 FMN-dependent dehydrogenase 14 377 8.1E-125 T 14-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 LH59_13055 9fd0838f970b10034712e6538687ac04 380 Gene3D G3DSA:3.20.20.70 1 378 3.0E-121 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_13055 9fd0838f970b10034712e6538687ac04 380 PIRSF PIRSF000138 1 380 1.0E-126 T 14-10-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 Reactome: R-HSA-9033241 LH59_21225 e0c0887afd44060d0b3512e5f4bccd7e 147 Gene3D G3DSA:1.10.10.10 48 145 4.6E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_21225 e0c0887afd44060d0b3512e5f4bccd7e 147 Pfam PF00486 Transcriptional regulatory protein, C terminal 59 137 2.5E-11 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_21225 e0c0887afd44060d0b3512e5f4bccd7e 147 SMART SM00862 59 137 7.3E-10 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_21225 e0c0887afd44060d0b3512e5f4bccd7e 147 SUPERFAMILY SSF46894 52 138 1.02E-12 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LH59_06945 998b989015118aab8c98d965e2f01bce 410 Pfam PF01546 Peptidase family M20/M25/M40 90 404 7.8E-27 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 LH59_06945 998b989015118aab8c98d965e2f01bce 410 Pfam PF07687 Peptidase dimerisation domain 192 302 1.8E-20 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain LH59_06945 998b989015118aab8c98d965e2f01bce 410 SUPERFAMILY SSF55031 196 312 2.75E-24 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain LH59_06945 998b989015118aab8c98d965e2f01bce 410 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 89 98 - T 14-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 LH59_06945 998b989015118aab8c98d965e2f01bce 410 SUPERFAMILY SSF53187 7 407 7.65E-50 T 14-10-2018 LH59_06945 998b989015118aab8c98d965e2f01bce 410 Gene3D G3DSA:3.30.70.360 196 316 4.5E-85 T 14-10-2018 LH59_06945 998b989015118aab8c98d965e2f01bce 410 Gene3D G3DSA:3.40.630.10 28 405 4.5E-85 T 14-10-2018 LH59_05590 35e98ffa830a178f0ee6d2e065a447a6 307 Gene3D G3DSA:1.10.3470.10 1 306 4.4E-39 T 14-10-2018 IPR037294 ABC transporter, BtuC-like LH59_05590 35e98ffa830a178f0ee6d2e065a447a6 307 SUPERFAMILY SSF81345 6 302 8.37E-40 T 14-10-2018 IPR037294 ABC transporter, BtuC-like LH59_05590 35e98ffa830a178f0ee6d2e065a447a6 307 Pfam PF01032 FecCD transport family 24 302 5.5E-37 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 LH59_12660 fcf9d1a60a6f121c87fed46e2c0b7af4 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LH59_12660 fcf9d1a60a6f121c87fed46e2c0b7af4 256 SUPERFAMILY SSF51735 10 239 1.74E-62 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_12660 fcf9d1a60a6f121c87fed46e2c0b7af4 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 1.7E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_12660 fcf9d1a60a6f121c87fed46e2c0b7af4 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 1.7E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_12660 fcf9d1a60a6f121c87fed46e2c0b7af4 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 1.7E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_12660 fcf9d1a60a6f121c87fed46e2c0b7af4 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 2.4E-22 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_12660 fcf9d1a60a6f121c87fed46e2c0b7af4 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 2.4E-22 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_12660 fcf9d1a60a6f121c87fed46e2c0b7af4 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 2.4E-22 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_12660 fcf9d1a60a6f121c87fed46e2c0b7af4 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 2.4E-22 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_12660 fcf9d1a60a6f121c87fed46e2c0b7af4 256 Pfam PF00106 short chain dehydrogenase 11 202 2.4E-51 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_12660 fcf9d1a60a6f121c87fed46e2c0b7af4 256 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 10 184 3.5E-4 T 14-10-2018 LH59_12660 fcf9d1a60a6f121c87fed46e2c0b7af4 256 Gene3D G3DSA:3.40.50.720 10 256 5.2E-69 T 14-10-2018 LH59_24925 4359b2f63edd4ec8d073db5ef28892d9 113 SUPERFAMILY SSF47413 3 56 3.49E-12 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 LH59_24925 4359b2f63edd4ec8d073db5ef28892d9 113 Gene3D G3DSA:1.10.260.40 2 54 8.5E-14 T 14-10-2018 LH59_24925 4359b2f63edd4ec8d073db5ef28892d9 113 Pfam PF01381 Helix-turn-helix 3 51 1.3E-11 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LH59_24925 4359b2f63edd4ec8d073db5ef28892d9 113 SMART SM00530 1 51 2.0E-6 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LH59_06560 a7652414c0c391bad8aba1c997c23580 296 Gene3D G3DSA:3.30.300.20 185 296 1.1E-36 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta LH59_06560 a7652414c0c391bad8aba1c997c23580 296 Gene3D G3DSA:3.40.50.300 7 183 2.7E-44 T 14-10-2018 LH59_06560 a7652414c0c391bad8aba1c997c23580 296 Pfam PF07650 KH domain 208 283 1.0E-15 T 14-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_06560 a7652414c0c391bad8aba1c997c23580 296 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 168 4.4E-23 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 LH59_06560 a7652414c0c391bad8aba1c997c23580 296 TIGRFAM TIGR00436 era: GTP-binding protein Era 9 278 1.3E-77 T 14-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_06560 a7652414c0c391bad8aba1c997c23580 296 SUPERFAMILY SSF54814 181 296 2.49E-37 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 LH59_06560 a7652414c0c391bad8aba1c997c23580 296 Hamap MF_00367 GTPase Era [era]. 6 295 33.97 T 14-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_06560 a7652414c0c391bad8aba1c997c23580 296 SUPERFAMILY SSF52540 11 202 4.0E-41 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_06560 a7652414c0c391bad8aba1c997c23580 296 Pfam PF01926 50S ribosome-binding GTPase 11 112 1.6E-23 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 LH59_06560 a7652414c0c391bad8aba1c997c23580 296 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 79 97 6.5E-7 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 LH59_06560 a7652414c0c391bad8aba1c997c23580 296 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 11 31 6.5E-7 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 LH59_07380 59c94ff95ea601b84fa9c694ac6cafec 567 Pfam PF02080 TrkA-C domain 308 372 1.2E-6 T 14-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 LH59_07380 59c94ff95ea601b84fa9c694ac6cafec 567 Pfam PF06826 Predicted Permease Membrane Region 15 177 2.9E-28 T 14-10-2018 IPR006512 YidE/YbjL duplication LH59_07380 59c94ff95ea601b84fa9c694ac6cafec 567 Pfam PF06826 Predicted Permease Membrane Region 391 559 4.9E-33 T 14-10-2018 IPR006512 YidE/YbjL duplication LH59_07380 59c94ff95ea601b84fa9c694ac6cafec 567 TIGRFAM TIGR01625 YidE_YbjL_dupl: AspT/YidE/YbjL antiporter duplication domain 397 546 2.3E-28 T 14-10-2018 IPR006512 YidE/YbjL duplication LH59_07380 59c94ff95ea601b84fa9c694ac6cafec 567 SUPERFAMILY SSF116726 228 286 7.19E-6 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 LH59_07380 59c94ff95ea601b84fa9c694ac6cafec 567 TIGRFAM TIGR03802 Asp_Ala_antiprt: aspartate-alanine antiporter 6 561 1.3E-187 T 14-10-2018 IPR022457 Aspartate-alanine antiporter GO:0005215|GO:0016020 LH59_07380 59c94ff95ea601b84fa9c694ac6cafec 567 SUPERFAMILY SSF116726 304 377 1.83E-6 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 LH59_02405 e36f4515c7b454e2f5fc6e6c838206f2 233 SUPERFAMILY SSF46785 5 75 6.78E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_02405 e36f4515c7b454e2f5fc6e6c838206f2 233 SMART SM00895 81 206 1.7E-10 T 14-10-2018 IPR011711 GntR, C-terminal LH59_02405 e36f4515c7b454e2f5fc6e6c838206f2 233 SUPERFAMILY SSF48008 78 212 2.62E-15 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_02405 e36f4515c7b454e2f5fc6e6c838206f2 233 Gene3D G3DSA:1.10.10.10 13 72 3.1E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_02405 e36f4515c7b454e2f5fc6e6c838206f2 233 Pfam PF07729 FCD domain 82 201 4.4E-15 T 14-10-2018 IPR011711 GntR, C-terminal LH59_02405 e36f4515c7b454e2f5fc6e6c838206f2 233 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 31 45 6.7E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_02405 e36f4515c7b454e2f5fc6e6c838206f2 233 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 61 6.7E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_02405 e36f4515c7b454e2f5fc6e6c838206f2 233 SMART SM00345 13 71 3.6E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_02405 e36f4515c7b454e2f5fc6e6c838206f2 233 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 71 4.7E-18 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_02405 e36f4515c7b454e2f5fc6e6c838206f2 233 Gene3D G3DSA:1.20.120.530 75 213 6.5E-17 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_21055 fe869c7322cea044fbc14b63389b481f 390 Pfam PF13378 Enolase C-terminal domain-like 161 381 3.6E-54 T 14-10-2018 IPR029065 Enolase C-terminal domain-like LH59_21055 fe869c7322cea044fbc14b63389b481f 390 SMART SM00922 158 261 6.5E-24 T 14-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal LH59_21055 fe869c7322cea044fbc14b63389b481f 390 SUPERFAMILY SSF54826 1 143 1.7E-34 T 14-10-2018 LH59_21055 fe869c7322cea044fbc14b63389b481f 390 Gene3D G3DSA:3.30.390.10 3 136 3.9E-181 T 14-10-2018 IPR029017 Enolase-like, N-terminal LH59_21055 fe869c7322cea044fbc14b63389b481f 390 Gene3D G3DSA:3.20.20.120 137 384 3.9E-181 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily LH59_21055 fe869c7322cea044fbc14b63389b481f 390 SUPERFAMILY SSF51604 127 386 1.02E-68 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily LH59_21055 fe869c7322cea044fbc14b63389b481f 390 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 39 139 7.4E-22 T 14-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain LH59_05825 c8f074320914e9ab990fd569bcbdc6b1 227 ProSitePatterns PS00211 ABC transporters family signature. 122 136 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_05825 c8f074320914e9ab990fd569bcbdc6b1 227 Pfam PF00005 ABC transporter 17 149 4.8E-23 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_05825 c8f074320914e9ab990fd569bcbdc6b1 227 Gene3D G3DSA:3.40.50.300 1 218 6.0E-58 T 14-10-2018 LH59_05825 c8f074320914e9ab990fd569bcbdc6b1 227 SUPERFAMILY SSF52540 1 204 5.09E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_05825 c8f074320914e9ab990fd569bcbdc6b1 227 SMART SM00382 26 199 3.5E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_21660 043d87b228210f4409a7fbb8f78cf319 96 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 77 1.2E-12 T 14-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain LH59_21660 043d87b228210f4409a7fbb8f78cf319 96 SUPERFAMILY SSF54909 1 96 2.39E-30 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel LH59_21660 043d87b228210f4409a7fbb8f78cf319 96 Gene3D G3DSA:3.30.70.100 1 96 4.8E-39 T 14-10-2018 LH59_25415 e13b6f1cfcf80269df452e8ce6bd9170 440 Gene3D G3DSA:1.20.1600.10 18 439 7.5E-84 T 14-10-2018 LH59_25415 e13b6f1cfcf80269df452e8ce6bd9170 440 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 15 437 7.1E-90 T 14-10-2018 IPR010130 Type I secretion outer membrane protein, TolC GO:0015562|GO:0019867|GO:0055085 LH59_25415 e13b6f1cfcf80269df452e8ce6bd9170 440 Pfam PF02321 Outer membrane efflux protein 19 211 8.1E-21 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 LH59_25415 e13b6f1cfcf80269df452e8ce6bd9170 440 Pfam PF02321 Outer membrane efflux protein 237 418 5.2E-25 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 LH59_25415 e13b6f1cfcf80269df452e8ce6bd9170 440 SUPERFAMILY SSF56954 3 428 3.14E-72 T 14-10-2018 LH59_06870 672cf2a1cf5ebafed953980a3ae59242 401 Pfam PF00285 Citrate synthase, C-terminal domain 34 383 3.1E-113 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 LH59_06870 672cf2a1cf5ebafed953980a3ae59242 401 PRINTS PR00143 Citrate synthase signature 276 296 2.6E-35 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 LH59_06870 672cf2a1cf5ebafed953980a3ae59242 401 PRINTS PR00143 Citrate synthase signature 201 216 2.6E-35 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 LH59_06870 672cf2a1cf5ebafed953980a3ae59242 401 PRINTS PR00143 Citrate synthase signature 223 251 2.6E-35 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 LH59_06870 672cf2a1cf5ebafed953980a3ae59242 401 PRINTS PR00143 Citrate synthase signature 151 164 2.6E-35 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 LH59_06870 672cf2a1cf5ebafed953980a3ae59242 401 PRINTS PR00143 Citrate synthase signature 353 367 2.6E-35 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 LH59_06870 672cf2a1cf5ebafed953980a3ae59242 401 PRINTS PR00143 Citrate synthase signature 333 349 2.6E-35 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 LH59_06870 672cf2a1cf5ebafed953980a3ae59242 401 Gene3D G3DSA:1.10.580.10 54 380 1.1E-125 T 14-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 LH59_06870 672cf2a1cf5ebafed953980a3ae59242 401 PIRSF PIRSF001369 27 401 1.5E-110 T 14-10-2018 IPR024176 Citrate synthase, bacterial-type LH59_06870 672cf2a1cf5ebafed953980a3ae59242 401 Gene3D G3DSA:1.10.230.10 249 347 1.1E-125 T 14-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain LH59_06870 672cf2a1cf5ebafed953980a3ae59242 401 ProSitePatterns PS00480 Citrate synthase signature. 283 295 - T 14-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 LH59_06870 672cf2a1cf5ebafed953980a3ae59242 401 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 33 400 2.7E-158 T 14-10-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 LH59_06870 672cf2a1cf5ebafed953980a3ae59242 401 SUPERFAMILY SSF48256 33 400 3.14E-123 T 14-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 LH59_06035 3d12b7232e0079918a6db46d7cca6664 463 Gene3D G3DSA:2.20.200.10 94 344 5.3E-131 T 14-10-2018 LH59_06035 3d12b7232e0079918a6db46d7cca6664 463 Pfam PF02321 Outer membrane efflux protein 57 245 9.5E-24 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 LH59_06035 3d12b7232e0079918a6db46d7cca6664 463 Pfam PF02321 Outer membrane efflux protein 272 453 5.1E-28 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 LH59_06035 3d12b7232e0079918a6db46d7cca6664 463 Gene3D G3DSA:1.20.1600.10 48 455 5.3E-131 T 14-10-2018 LH59_06035 3d12b7232e0079918a6db46d7cca6664 463 SUPERFAMILY SSF56954 2 456 9.55E-107 T 14-10-2018 LH59_06035 3d12b7232e0079918a6db46d7cca6664 463 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 8 454 2.0E-121 T 14-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 LH59_01325 161897659adcdea940cc5f24cd107442 412 Gene3D G3DSA:1.20.1250.20 13 405 9.6E-40 T 14-10-2018 LH59_01325 161897659adcdea940cc5f24cd107442 412 Pfam PF07690 Major Facilitator Superfamily 25 326 1.6E-29 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_01325 161897659adcdea940cc5f24cd107442 412 SUPERFAMILY SSF103473 14 405 1.83E-49 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_10200 445d2a54161e17badd54cfa28d27e93d 508 Pfam PF00155 Aminotransferase class I and II 158 446 1.3E-22 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LH59_10200 445d2a54161e17badd54cfa28d27e93d 508 Gene3D G3DSA:3.40.640.10 134 498 2.0E-110 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_10200 445d2a54161e17badd54cfa28d27e93d 508 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 58 1.4E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_10200 445d2a54161e17badd54cfa28d27e93d 508 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 58 74 1.4E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_10200 445d2a54161e17badd54cfa28d27e93d 508 SUPERFAMILY SSF53383 130 502 5.62E-80 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_10200 445d2a54161e17badd54cfa28d27e93d 508 SMART SM00345 25 83 1.8E-9 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_10200 445d2a54161e17badd54cfa28d27e93d 508 Gene3D G3DSA:1.10.10.10 18 114 7.2E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_10200 445d2a54161e17badd54cfa28d27e93d 508 SUPERFAMILY SSF46785 18 87 1.41E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_10200 445d2a54161e17badd54cfa28d27e93d 508 Pfam PF00392 Bacterial regulatory proteins, gntR family 23 83 1.6E-12 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_10975 0e5bdb2ef78bb391152d85b740118d96 323 Pfam PF16220 Domain of unknown function (DUF4880) 11 50 6.4E-14 T 14-10-2018 IPR032623 FecR, N-terminal LH59_10975 0e5bdb2ef78bb391152d85b740118d96 323 Gene3D G3DSA:2.60.120.1440 99 234 4.6E-22 T 14-10-2018 LH59_10975 0e5bdb2ef78bb391152d85b740118d96 323 Pfam PF04773 FecR protein 113 201 5.0E-18 T 14-10-2018 IPR006860 FecR protein LH59_10975 0e5bdb2ef78bb391152d85b740118d96 323 PIRSF PIRSF018266 2 316 6.3E-81 T 14-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component LH59_01180 7bbe7eac47d22d79a9e0c454ab330c13 73 Pfam PF12512 Protein of unknown function (DUF3717) 3 68 1.6E-26 T 14-10-2018 IPR022191 Protein of unknown function DUF3717 LH59_19155 de39ab059f47a9a4b49ddbad5d4ac8b3 207 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 27 159 1.5E-24 T 14-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ LH59_14075 0fa393a105a0a5bd0da0934690d7531e 465 SUPERFAMILY SSF51905 4 272 1.76E-17 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_14075 0fa393a105a0a5bd0da0934690d7531e 465 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 4 341 2.2E-120 T 14-10-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase LH59_14075 0fa393a105a0a5bd0da0934690d7531e 465 Gene3D G3DSA:3.50.50.60 1 424 9.1E-113 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_10615 9ed608742669093fc0df0cb5cb28a70a 264 SUPERFAMILY SSF52096 8 259 2.67E-61 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily LH59_10615 9ed608742669093fc0df0cb5cb28a70a 264 Gene3D G3DSA:3.90.226.10 12 261 9.0E-61 T 14-10-2018 LH59_10615 9ed608742669093fc0df0cb5cb28a70a 264 Pfam PF00378 Enoyl-CoA hydratase/isomerase 18 258 2.6E-28 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 LH59_01060 19910f87346682a722d151f8a59e82ca 462 SUPERFAMILY SSF56059 93 360 7.95E-69 T 14-10-2018 LH59_01060 19910f87346682a722d151f8a59e82ca 462 Pfam PF00289 Biotin carboxylase, N-terminal domain 12 120 4.8E-43 T 14-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LH59_01060 19910f87346682a722d151f8a59e82ca 462 SUPERFAMILY SSF51246 341 456 2.98E-41 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 LH59_01060 19910f87346682a722d151f8a59e82ca 462 SUPERFAMILY SSF52440 9 123 2.73E-46 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily LH59_01060 19910f87346682a722d151f8a59e82ca 462 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 125 332 5.7E-75 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 LH59_01060 19910f87346682a722d151f8a59e82ca 462 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 296 303 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 LH59_01060 19910f87346682a722d151f8a59e82ca 462 Pfam PF02785 Biotin carboxylase C-terminal domain 346 452 1.0E-38 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LH59_01060 19910f87346682a722d151f8a59e82ca 462 Gene3D G3DSA:3.30.470.130 3 458 4.8E-193 T 14-10-2018 LH59_01060 19910f87346682a722d151f8a59e82ca 462 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 13 456 8.8E-191 T 14-10-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 LH59_01060 19910f87346682a722d151f8a59e82ca 462 SMART SM00878 346 452 4.8E-61 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 LH59_01060 19910f87346682a722d151f8a59e82ca 462 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 163 177 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 LH59_09030 c88755dd3a9db3c8df089b2304c16c9c 182 ProSitePatterns PS01117 MarR-type HTH domain signature. 73 107 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site LH59_09030 c88755dd3a9db3c8df089b2304c16c9c 182 Gene3D G3DSA:1.10.10.10 8 146 3.1E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_09030 c88755dd3a9db3c8df089b2304c16c9c 182 SUPERFAMILY SSF46785 13 149 3.19E-31 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_09030 c88755dd3a9db3c8df089b2304c16c9c 182 Pfam PF01047 MarR family 41 99 9.7E-17 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_09030 c88755dd3a9db3c8df089b2304c16c9c 182 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 90 1.0E-6 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_09030 c88755dd3a9db3c8df089b2304c16c9c 182 PRINTS PR00598 Bacterial regulatory protein MarR family signature 58 74 1.0E-6 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_09030 c88755dd3a9db3c8df089b2304c16c9c 182 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 110 1.0E-6 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_09030 c88755dd3a9db3c8df089b2304c16c9c 182 SMART SM00347 34 134 3.5E-25 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_08745 0b6707699389560d6bce9f9b05a52ba5 371 SUPERFAMILY SSF53756 3 369 6.6E-66 T 14-10-2018 LH59_08745 0b6707699389560d6bce9f9b05a52ba5 371 Gene3D G3DSA:3.40.50.2000 2 179 2.4E-22 T 14-10-2018 LH59_08745 0b6707699389560d6bce9f9b05a52ba5 371 Pfam PF00534 Glycosyl transferases group 1 191 345 1.4E-22 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 LH59_08745 0b6707699389560d6bce9f9b05a52ba5 371 Pfam PF13439 Glycosyltransferase Family 4 14 167 1.7E-21 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 LH59_08745 0b6707699389560d6bce9f9b05a52ba5 371 Gene3D G3DSA:3.40.50.2000 180 351 4.9E-32 T 14-10-2018 LH59_09365 8c6e5fa728d3fcf063c054d01238f70b 355 Hamap MF_00300 Chorismate synthase [aroC]. 10 352 35.547 T 14-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 LH59_09365 8c6e5fa728d3fcf063c054d01238f70b 355 SUPERFAMILY SSF103263 4 351 1.44E-143 T 14-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 LH59_09365 8c6e5fa728d3fcf063c054d01238f70b 355 PIRSF PIRSF001456 3 353 2.0E-132 T 14-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 LH59_09365 8c6e5fa728d3fcf063c054d01238f70b 355 ProSitePatterns PS00788 Chorismate synthase signature 2. 124 140 - T 14-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 LH59_09365 8c6e5fa728d3fcf063c054d01238f70b 355 Pfam PF01264 Chorismate synthase 10 345 9.7E-132 T 14-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 LH59_09365 8c6e5fa728d3fcf063c054d01238f70b 355 TIGRFAM TIGR00033 aroC: chorismate synthase 10 349 9.3E-136 T 14-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 LH59_09365 8c6e5fa728d3fcf063c054d01238f70b 355 Gene3D G3DSA:3.60.150.10 1 353 2.5E-146 T 14-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 LH59_09365 8c6e5fa728d3fcf063c054d01238f70b 355 ProSitePatterns PS00789 Chorismate synthase signature 3. 319 335 - T 14-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 LH59_09365 8c6e5fa728d3fcf063c054d01238f70b 355 ProSitePatterns PS00787 Chorismate synthase signature 1. 16 31 - T 14-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 LH59_07180 f6cc4d2804dfca85f221ee75df2360d5 376 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 116 2.7E-33 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 LH59_07180 f6cc4d2804dfca85f221ee75df2360d5 376 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 374 6.0E-35 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LH59_07180 f6cc4d2804dfca85f221ee75df2360d5 376 Gene3D G3DSA:1.20.140.10 235 376 1.3E-35 T 14-10-2018 LH59_07180 f6cc4d2804dfca85f221ee75df2360d5 376 Gene3D G3DSA:1.10.540.10 1 118 7.1E-36 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 LH59_07180 f6cc4d2804dfca85f221ee75df2360d5 376 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 122 134 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 LH59_07180 f6cc4d2804dfca85f221ee75df2360d5 376 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 120 214 3.8E-24 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 LH59_07180 f6cc4d2804dfca85f221ee75df2360d5 376 Gene3D G3DSA:2.40.110.10 119 234 1.7E-39 T 14-10-2018 LH59_07180 f6cc4d2804dfca85f221ee75df2360d5 376 SUPERFAMILY SSF56645 4 238 1.57E-79 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 LH59_07180 f6cc4d2804dfca85f221ee75df2360d5 376 SUPERFAMILY SSF47203 226 373 1.77E-36 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 LH59_07180 f6cc4d2804dfca85f221ee75df2360d5 376 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 334 353 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 LH59_06085 7ecb8806d61d9fb050d72e5a9969dbf2 144 Gene3D G3DSA:3.40.50.720 1 136 1.0E-20 T 14-10-2018 LH59_06085 7ecb8806d61d9fb050d72e5a9969dbf2 144 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 123 1.1E-9 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 LH59_06085 7ecb8806d61d9fb050d72e5a9969dbf2 144 SUPERFAMILY SSF51735 4 124 1.01E-14 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_25895 1f5328733cc4079a0246bbb59354751c 181 Pfam PF13420 Acetyltransferase (GNAT) domain 10 164 4.9E-22 T 14-10-2018 LH59_25895 1f5328733cc4079a0246bbb59354751c 181 SUPERFAMILY SSF55729 10 173 7.67E-32 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_25895 1f5328733cc4079a0246bbb59354751c 181 Gene3D G3DSA:3.40.630.30 5 180 3.0E-52 T 14-10-2018 LH59_23120 85c8d0e5ed9890d248f1b7fe1a646d6a 733 Pfam PF07715 TonB-dependent Receptor Plug Domain 66 166 3.9E-21 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_23120 85c8d0e5ed9890d248f1b7fe1a646d6a 733 SUPERFAMILY SSF56935 25 733 1.81E-114 T 14-10-2018 LH59_23120 85c8d0e5ed9890d248f1b7fe1a646d6a 733 Gene3D G3DSA:2.170.130.10 49 177 4.9E-27 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily LH59_23120 85c8d0e5ed9890d248f1b7fe1a646d6a 733 Pfam PF00593 TonB dependent receptor 290 731 2.6E-41 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_23120 85c8d0e5ed9890d248f1b7fe1a646d6a 733 Gene3D G3DSA:2.40.170.20 178 733 3.2E-84 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_00630 44af11f8be83a896ddfb1e63cec3aea8 210 SUPERFAMILY SSF52833 39 198 7.67E-36 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_00630 44af11f8be83a896ddfb1e63cec3aea8 210 ProSitePatterns PS00194 Thioredoxin family active site. 50 68 - T 14-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 LH59_00630 44af11f8be83a896ddfb1e63cec3aea8 210 Pfam PF01323 DSBA-like thioredoxin domain 50 184 1.0E-14 T 14-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 LH59_00630 44af11f8be83a896ddfb1e63cec3aea8 210 Gene3D G3DSA:3.40.30.10 27 210 2.5E-47 T 14-10-2018 LH59_00630 44af11f8be83a896ddfb1e63cec3aea8 210 PIRSF PIRSF001488 4 210 2.9E-60 T 14-10-2018 IPR023205 Thiol:disulphide interchange protein DsbA/DsbL LH59_03415 08696c45aeeecbc45707b9c4ef68b17d 416 Gene3D G3DSA:3.40.640.10 37 286 9.1E-182 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_03415 08696c45aeeecbc45707b9c4ef68b17d 416 PIRSF PIRSF000412 1 416 2.1E-164 T 14-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 LH59_03415 08696c45aeeecbc45707b9c4ef68b17d 416 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 7 414 51.896 T 14-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 LH59_03415 08696c45aeeecbc45707b9c4ef68b17d 416 Pfam PF00464 Serine hydroxymethyltransferase 8 382 1.9E-170 T 14-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 LH59_03415 08696c45aeeecbc45707b9c4ef68b17d 416 Gene3D G3DSA:3.90.1150.10 10 392 9.1E-182 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_03415 08696c45aeeecbc45707b9c4ef68b17d 416 SUPERFAMILY SSF53383 8 414 3.2E-178 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_03415 08696c45aeeecbc45707b9c4ef68b17d 416 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 221 237 - T 14-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 LH59_12445 823ea29d0c56fc0af50137161d68678e 219 SUPERFAMILY SSF52266 38 218 3.36E-50 T 14-10-2018 LH59_12445 823ea29d0c56fc0af50137161d68678e 219 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 43 204 5.6E-26 T 14-10-2018 IPR013830 SGNH hydrolase-type esterase domain LH59_12445 823ea29d0c56fc0af50137161d68678e 219 Gene3D G3DSA:3.40.50.1110 39 219 1.1E-68 T 14-10-2018 IPR036514 SGNH hydrolase superfamily LH59_25845 0b1f3c57696e72a661b28eb3dc743cbe 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 1.6E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25845 0b1f3c57696e72a661b28eb3dc743cbe 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 1.6E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25845 0b1f3c57696e72a661b28eb3dc743cbe 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 1.6E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25845 0b1f3c57696e72a661b28eb3dc743cbe 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 1.6E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25845 0b1f3c57696e72a661b28eb3dc743cbe 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 1.6E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25845 0b1f3c57696e72a661b28eb3dc743cbe 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 1.6E-42 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25845 0b1f3c57696e72a661b28eb3dc743cbe 262 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 15 230 1.3E-4 T 14-10-2018 LH59_25845 0b1f3c57696e72a661b28eb3dc743cbe 262 Gene3D G3DSA:3.40.50.720 2 260 4.5E-91 T 14-10-2018 LH59_25845 0b1f3c57696e72a661b28eb3dc743cbe 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 5.0E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25845 0b1f3c57696e72a661b28eb3dc743cbe 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 90 101 5.0E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25845 0b1f3c57696e72a661b28eb3dc743cbe 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 5.0E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25845 0b1f3c57696e72a661b28eb3dc743cbe 262 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 150 178 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LH59_25845 0b1f3c57696e72a661b28eb3dc743cbe 262 SUPERFAMILY SSF51735 13 258 2.04E-88 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_25845 0b1f3c57696e72a661b28eb3dc743cbe 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 257 2.3E-72 T 14-10-2018 LH59_22580 d55f9113071a411a116b6e2f62c3b15d 327 Gene3D G3DSA:3.40.190.10 130 251 7.1E-117 T 14-10-2018 LH59_22580 d55f9113071a411a116b6e2f62c3b15d 327 SUPERFAMILY SSF53850 118 289 1.02E-13 T 14-10-2018 LH59_22580 d55f9113071a411a116b6e2f62c3b15d 327 Gene3D G3DSA:3.40.190.150 32 316 7.1E-117 T 14-10-2018 LH59_22580 d55f9113071a411a116b6e2f62c3b15d 327 PIRSF PIRSF017082 1 326 2.3E-86 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_22580 d55f9113071a411a116b6e2f62c3b15d 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 320 2.7E-88 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_04560 50800f39a6ddfb91019abea08baec76d 461 Gene3D G3DSA:1.10.3090.10 178 422 1.6E-84 T 14-10-2018 LH59_04560 50800f39a6ddfb91019abea08baec76d 461 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 208 266 5.6E-19 T 14-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 LH59_04560 50800f39a6ddfb91019abea08baec76d 461 SUPERFAMILY SSF81891 178 410 3.01E-52 T 14-10-2018 LH59_04560 50800f39a6ddfb91019abea08baec76d 461 Gene3D G3DSA:3.30.460.10 23 175 4.0E-59 T 14-10-2018 LH59_04560 50800f39a6ddfb91019abea08baec76d 461 Pfam PF01743 Poly A polymerase head domain 54 179 1.6E-36 T 14-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 LH59_04560 50800f39a6ddfb91019abea08baec76d 461 TIGRFAM TIGR01942 pcnB: poly(A) polymerase 26 447 2.0E-156 T 14-10-2018 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 LH59_04560 50800f39a6ddfb91019abea08baec76d 461 SUPERFAMILY SSF81301 29 176 1.01E-41 T 14-10-2018 LH59_04560 50800f39a6ddfb91019abea08baec76d 461 Pfam PF12626 Polymerase A arginine-rich C-terminus 319 444 7.6E-41 T 14-10-2018 IPR025866 Polymerase A arginine-rich C-terminal domain LH59_04560 50800f39a6ddfb91019abea08baec76d 461 Hamap MF_00957 Poly(A) polymerase I [pcnB]. 18 445 37.185 T 14-10-2018 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 LH59_14835 152d2f238dfa4acea664068bd8420d3f 1358 SUPERFAMILY SSF51126 398 1072 5.96E-39 T 14-10-2018 IPR011050 Pectin lyase fold/virulence factor LH59_14835 152d2f238dfa4acea664068bd8420d3f 1358 Pfam PF02395 Immunoglobulin A1 protease 6 742 6.6E-98 T 14-10-2018 IPR000710 Peptidase S6, IgA endopeptidase GO:0004252|GO:0006508 LH59_14835 152d2f238dfa4acea664068bd8420d3f 1358 PRINTS PR00921 IgA-specific serine endopeptidase (S6) signature 20 40 3.4E-18 T 14-10-2018 IPR000710 Peptidase S6, IgA endopeptidase GO:0004252|GO:0006508 LH59_14835 152d2f238dfa4acea664068bd8420d3f 1358 PRINTS PR00921 IgA-specific serine endopeptidase (S6) signature 651 673 3.4E-18 T 14-10-2018 IPR000710 Peptidase S6, IgA endopeptidase GO:0004252|GO:0006508 LH59_14835 152d2f238dfa4acea664068bd8420d3f 1358 PRINTS PR00921 IgA-specific serine endopeptidase (S6) signature 122 142 3.4E-18 T 14-10-2018 IPR000710 Peptidase S6, IgA endopeptidase GO:0004252|GO:0006508 LH59_14835 152d2f238dfa4acea664068bd8420d3f 1358 PRINTS PR00921 IgA-specific serine endopeptidase (S6) signature 240 258 3.4E-18 T 14-10-2018 IPR000710 Peptidase S6, IgA endopeptidase GO:0004252|GO:0006508 LH59_14835 152d2f238dfa4acea664068bd8420d3f 1358 Gene3D G3DSA:2.40.10.120 13 309 6.3E-73 T 14-10-2018 LH59_14835 152d2f238dfa4acea664068bd8420d3f 1358 Gene3D G3DSA:2.160.20.20 1094 1256 5.9E-27 T 14-10-2018 IPR012332 P22 tailspike-like, C-terminal domain superfamily LH59_00620 4fe346466eb03c410441c9273a491811 319 SUPERFAMILY SSF53474 58 317 2.96E-31 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_00620 4fe346466eb03c410441c9273a491811 319 Gene3D G3DSA:3.40.50.1820 2 319 1.1E-96 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_18105 9eb51bd23263fb2cb7e88b24b1614ece 239 SUPERFAMILY SSF51735 2 235 5.62E-69 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_18105 9eb51bd23263fb2cb7e88b24b1614ece 239 Gene3D G3DSA:3.40.50.720 1 236 4.0E-69 T 14-10-2018 LH59_18105 9eb51bd23263fb2cb7e88b24b1614ece 239 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 232 3.1E-51 T 14-10-2018 LH59_18105 9eb51bd23263fb2cb7e88b24b1614ece 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 121 129 3.5E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_18105 9eb51bd23263fb2cb7e88b24b1614ece 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 68 79 3.5E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_18105 9eb51bd23263fb2cb7e88b24b1614ece 239 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 159 3.5E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_18105 9eb51bd23263fb2cb7e88b24b1614ece 239 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 171 0.0082 T 14-10-2018 LH59_18105 9eb51bd23263fb2cb7e88b24b1614ece 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 178 3.8E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_18105 9eb51bd23263fb2cb7e88b24b1614ece 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 115 131 3.8E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_18105 9eb51bd23263fb2cb7e88b24b1614ece 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 197 217 3.8E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_18105 9eb51bd23263fb2cb7e88b24b1614ece 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 159 3.8E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_18105 9eb51bd23263fb2cb7e88b24b1614ece 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 68 79 3.8E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_18105 9eb51bd23263fb2cb7e88b24b1614ece 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 3.8E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_21410 2ad3b0f2c8667749fb620ff84faee006 303 Gene3D G3DSA:3.40.50.720 8 296 2.2E-38 T 14-10-2018 LH59_21410 2ad3b0f2c8667749fb620ff84faee006 303 Pfam PF01370 NAD dependent epimerase/dehydratase family 10 197 1.8E-19 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 LH59_21410 2ad3b0f2c8667749fb620ff84faee006 303 SUPERFAMILY SSF51735 9 210 1.7E-28 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_26565 e7074c12f4a3d2c1dfd11ea161edda89 127 Pfam PF13663 Domain of unknown function (DUF4148) 92 123 2.3E-8 T 14-10-2018 IPR025421 Protein of unknown function DUF4148 LH59_26565 e7074c12f4a3d2c1dfd11ea161edda89 127 Pfam PF13663 Domain of unknown function (DUF4148) 1 51 1.2E-12 T 14-10-2018 IPR025421 Protein of unknown function DUF4148 LH59_26565 e7074c12f4a3d2c1dfd11ea161edda89 127 Pfam PF13663 Domain of unknown function (DUF4148) 56 86 4.4E-8 T 14-10-2018 IPR025421 Protein of unknown function DUF4148 LH59_28205 c47065f921da9544f9dcf765f5dbd5cd 331 Gene3D G3DSA:3.40.50.300 9 329 2.8E-94 T 14-10-2018 LH59_28205 c47065f921da9544f9dcf765f5dbd5cd 331 SUPERFAMILY SSF52540 11 260 1.25E-64 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_28205 c47065f921da9544f9dcf765f5dbd5cd 331 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_28205 c47065f921da9544f9dcf765f5dbd5cd 331 Pfam PF00005 ABC transporter 32 189 5.7E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_28205 c47065f921da9544f9dcf765f5dbd5cd 331 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 239 323 4.3E-27 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_28205 c47065f921da9544f9dcf765f5dbd5cd 331 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 241 305 1.2E-19 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_28205 c47065f921da9544f9dcf765f5dbd5cd 331 SMART SM00382 40 239 5.0E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_20505 50061897477db520a567859cab6f6ca0 72 Gene3D G3DSA:3.30.1660.10 2 70 1.7E-36 T 14-10-2018 IPR025543 Dodecin-like LH59_20505 50061897477db520a567859cab6f6ca0 72 SUPERFAMILY SSF89807 5 70 1.01E-26 T 14-10-2018 IPR036694 Dodecin-like superfamily LH59_20505 50061897477db520a567859cab6f6ca0 72 Pfam PF07311 Dodecin 5 68 5.1E-31 T 14-10-2018 IPR009923 Dodecin LH59_12110 424e557c6ba9d8c0287fe28b9e4b6914 120 Pfam PF00486 Transcriptional regulatory protein, C terminal 34 115 2.6E-15 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_12110 424e557c6ba9d8c0287fe28b9e4b6914 120 SUPERFAMILY SSF46894 12 115 5.95E-18 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LH59_12110 424e557c6ba9d8c0287fe28b9e4b6914 120 Gene3D G3DSA:1.10.10.10 11 119 4.8E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_12110 424e557c6ba9d8c0287fe28b9e4b6914 120 SMART SM00862 34 115 6.0E-11 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_17705 a49ce11c12f28b9ceddf60ed8ebe8479 174 TIGRFAM TIGR00077 lspA: signal peptidase II 25 171 1.8E-39 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 LH59_17705 a49ce11c12f28b9ceddf60ed8ebe8479 174 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 18 172 16.814 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 LH59_17705 a49ce11c12f28b9ceddf60ed8ebe8479 174 ProSitePatterns PS00855 Signal peptidases II signature. 114 126 - T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 LH59_17705 a49ce11c12f28b9ceddf60ed8ebe8479 174 Pfam PF01252 Signal peptidase (SPase) II 26 166 2.2E-38 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 LH59_17705 a49ce11c12f28b9ceddf60ed8ebe8479 174 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 64 72 2.9E-17 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 LH59_17705 a49ce11c12f28b9ceddf60ed8ebe8479 174 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 111 126 2.9E-17 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 LH59_17705 a49ce11c12f28b9ceddf60ed8ebe8479 174 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 147 163 2.9E-17 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 LH59_22000 99f03222805c82f1b46346f9d33d4a25 384 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 16 380 1.7E-142 T 14-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 LH59_22000 99f03222805c82f1b46346f9d33d4a25 384 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 287 304 5.8E-39 T 14-10-2018 LH59_22000 99f03222805c82f1b46346f9d33d4a25 384 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 200 214 5.8E-39 T 14-10-2018 LH59_22000 99f03222805c82f1b46346f9d33d4a25 384 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 239 253 5.8E-39 T 14-10-2018 LH59_22000 99f03222805c82f1b46346f9d33d4a25 384 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 312 323 5.8E-39 T 14-10-2018 LH59_22000 99f03222805c82f1b46346f9d33d4a25 384 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 270 286 5.8E-39 T 14-10-2018 LH59_22000 99f03222805c82f1b46346f9d33d4a25 384 Gene3D G3DSA:3.50.30.20 14 160 2.4E-57 T 14-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 LH59_22000 99f03222805c82f1b46346f9d33d4a25 384 Gene3D G3DSA:3.40.50.880 161 382 4.6E-73 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_22000 99f03222805c82f1b46346f9d33d4a25 384 SUPERFAMILY SSF52317 165 382 1.68E-60 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_22000 99f03222805c82f1b46346f9d33d4a25 384 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 14 384 47.728 T 14-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 LH59_22000 99f03222805c82f1b46346f9d33d4a25 384 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 16 143 9.9E-52 T 14-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 LH59_22000 99f03222805c82f1b46346f9d33d4a25 384 SUPERFAMILY SSF52021 15 150 3.92E-56 T 14-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 LH59_22000 99f03222805c82f1b46346f9d33d4a25 384 Pfam PF00117 Glutamine amidotransferase class-I 203 378 7.4E-44 T 14-10-2018 IPR017926 Glutamine amidotransferase LH59_22000 99f03222805c82f1b46346f9d33d4a25 384 SMART SM01097 14 144 6.7E-92 T 14-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 LH59_22000 99f03222805c82f1b46346f9d33d4a25 384 PRINTS PR00096 Glutamine amidotransferase superfamily signature 242 251 2.3E-10 T 14-10-2018 LH59_22000 99f03222805c82f1b46346f9d33d4a25 384 PRINTS PR00096 Glutamine amidotransferase superfamily signature 355 368 2.3E-10 T 14-10-2018 LH59_22000 99f03222805c82f1b46346f9d33d4a25 384 PRINTS PR00096 Glutamine amidotransferase superfamily signature 270 281 2.3E-10 T 14-10-2018 LH59_12830 cf8e1db514ea824aa9f097f75790c1a7 425 SUPERFAMILY SSF51735 3 189 4.32E-44 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_12830 cf8e1db514ea824aa9f097f75790c1a7 425 PIRSF PIRSF000124 3 423 8.2E-49 T 14-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 LH59_12830 cf8e1db514ea824aa9f097f75790c1a7 425 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 4 176 8.3E-35 T 14-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 LH59_12830 cf8e1db514ea824aa9f097f75790c1a7 425 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 198 286 7.6E-24 T 14-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 LH59_12830 cf8e1db514ea824aa9f097f75790c1a7 425 Gene3D G3DSA:3.40.50.720 1 192 1.3E-59 T 14-10-2018 LH59_12830 cf8e1db514ea824aa9f097f75790c1a7 425 SMART SM00984 313 413 6.1E-19 T 14-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 LH59_12830 cf8e1db514ea824aa9f097f75790c1a7 425 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 314 412 1.1E-17 T 14-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 LH59_12830 cf8e1db514ea824aa9f097f75790c1a7 425 SUPERFAMILY SSF48179 197 287 7.99E-24 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 LH59_12830 cf8e1db514ea824aa9f097f75790c1a7 425 PIRSF PIRSF500136 1 425 2.9E-140 T 14-10-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 LH59_12830 cf8e1db514ea824aa9f097f75790c1a7 425 SUPERFAMILY SSF52413 299 412 2.22E-20 T 14-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 LH59_12830 cf8e1db514ea824aa9f097f75790c1a7 425 Gene3D G3DSA:3.40.50.720 196 423 1.4E-49 T 14-10-2018 LH59_12830 cf8e1db514ea824aa9f097f75790c1a7 425 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 4 407 4.8E-113 T 14-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 LH59_15640 1235ad27e15d199bc525ea9f4b7ce3b7 393 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 86 104 - T 14-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 LH59_15640 1235ad27e15d199bc525ea9f4b7ce3b7 393 SUPERFAMILY SSF53901 272 392 6.57E-42 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_15640 1235ad27e15d199bc525ea9f4b7ce3b7 393 ProSitePatterns PS00737 Thiolases signature 2. 339 355 - T 14-10-2018 IPR020613 Thiolase, conserved site GO:0016747 LH59_15640 1235ad27e15d199bc525ea9f4b7ce3b7 393 Pfam PF02803 Thiolase, C-terminal domain 271 391 5.9E-45 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 LH59_15640 1235ad27e15d199bc525ea9f4b7ce3b7 393 PIRSF PIRSF000429 1 393 4.0E-113 T 14-10-2018 IPR002155 Thiolase GO:0016747 LH59_15640 1235ad27e15d199bc525ea9f4b7ce3b7 393 Gene3D G3DSA:3.40.47.10 4 276 4.9E-132 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_15640 1235ad27e15d199bc525ea9f4b7ce3b7 393 SUPERFAMILY SSF53901 1 267 2.2E-63 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_15640 1235ad27e15d199bc525ea9f4b7ce3b7 393 Gene3D G3DSA:3.40.47.10 126 385 4.9E-132 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_15640 1235ad27e15d199bc525ea9f4b7ce3b7 393 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 391 1.5E-118 T 14-10-2018 IPR002155 Thiolase GO:0016747 LH59_15640 1235ad27e15d199bc525ea9f4b7ce3b7 393 ProSitePatterns PS00099 Thiolases active site. 374 387 - T 14-10-2018 IPR020610 Thiolase, active site GO:0016747 LH59_15640 1235ad27e15d199bc525ea9f4b7ce3b7 393 Pfam PF00108 Thiolase, N-terminal domain 5 262 1.6E-53 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 LH59_13855 149f65940d387eeec0cf01f1abd133f8 382 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 246 377 3.7E-14 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_13855 149f65940d387eeec0cf01f1abd133f8 382 SUPERFAMILY SSF161098 76 363 8.01E-33 T 14-10-2018 IPR035906 MetI-like superfamily LH59_13855 149f65940d387eeec0cf01f1abd133f8 382 Gene3D G3DSA:1.10.3720.10 176 379 1.3E-30 T 14-10-2018 IPR035906 MetI-like superfamily LH59_13855 149f65940d387eeec0cf01f1abd133f8 382 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 75 138 1.0E-14 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 LH59_11445 14d774a3078512626d8e45f8675faf6c 419 Pfam PF00669 Bacterial flagellin N-terminal helical region 4 140 1.8E-18 T 14-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 LH59_11445 14d774a3078512626d8e45f8675faf6c 419 SUPERFAMILY SSF64518 1 417 1.7E-65 T 14-10-2018 LH59_11445 14d774a3078512626d8e45f8675faf6c 419 TIGRFAM TIGR02550 flagell_flgL: flagellar hook-associated protein 3 2 416 1.0E-84 T 14-10-2018 IPR013384 Flagellar hook-associated protein 3 GO:0009424|GO:0071973 LH59_11445 14d774a3078512626d8e45f8675faf6c 419 Gene3D G3DSA:1.20.1330.10 267 366 1.2E-13 T 14-10-2018 LH59_11445 14d774a3078512626d8e45f8675faf6c 419 Gene3D G3DSA:1.20.1330.10 40 219 2.6E-43 T 14-10-2018 LH59_14725 aba59a1473ac36842fa0895b7e0c3973 418 Gene3D G3DSA:3.90.230.10 169 413 2.0E-30 T 14-10-2018 LH59_14725 aba59a1473ac36842fa0895b7e0c3973 418 Pfam PF00557 Metallopeptidase family M24 177 398 3.0E-17 T 14-10-2018 IPR000994 Peptidase M24 LH59_14725 aba59a1473ac36842fa0895b7e0c3973 418 SUPERFAMILY SSF53092 3 163 1.2E-7 T 14-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal LH59_14725 aba59a1473ac36842fa0895b7e0c3973 418 SUPERFAMILY SSF55920 169 408 7.07E-30 T 14-10-2018 IPR036005 Creatinase/aminopeptidase-like LH59_25010 5c01dff6681c7cb61533fdb9bf2de84d 288 SUPERFAMILY SSF103481 41 137 3.01E-10 T 14-10-2018 LH59_25010 5c01dff6681c7cb61533fdb9bf2de84d 288 Pfam PF00892 EamA-like transporter family 8 133 1.4E-12 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_25010 5c01dff6681c7cb61533fdb9bf2de84d 288 Pfam PF00892 EamA-like transporter family 144 275 9.0E-21 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_25010 5c01dff6681c7cb61533fdb9bf2de84d 288 SUPERFAMILY SSF103481 177 279 3.66E-16 T 14-10-2018 LH59_16240 10bff4b4ba8709c662425825ce5a6abf 523 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 64 433 3.5E-90 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain LH59_16240 10bff4b4ba8709c662425825ce5a6abf 523 Gene3D G3DSA:3.90.76.10 56 166 6.3E-129 T 14-10-2018 LH59_16240 10bff4b4ba8709c662425825ce5a6abf 523 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 70 91 - T 14-10-2018 IPR023765 Solute-binding protein family 5, conserved site LH59_16240 10bff4b4ba8709c662425825ce5a6abf 523 Gene3D G3DSA:3.40.190.10 34 269 6.3E-129 T 14-10-2018 LH59_16240 10bff4b4ba8709c662425825ce5a6abf 523 PIRSF PIRSF002741 6 520 6.5E-104 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 LH59_16240 10bff4b4ba8709c662425825ce5a6abf 523 SUPERFAMILY SSF53850 19 504 6.88E-128 T 14-10-2018 LH59_16240 10bff4b4ba8709c662425825ce5a6abf 523 Gene3D G3DSA:3.10.105.10 270 500 6.3E-129 T 14-10-2018 LH59_12015 75a41c449a2a6ab28f8efe87e0ff7112 160 Pfam PF04073 Aminoacyl-tRNA editing domain 23 148 2.8E-25 T 14-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 LH59_12015 75a41c449a2a6ab28f8efe87e0ff7112 160 Gene3D G3DSA:3.90.960.10 2 155 2.2E-40 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 LH59_12015 75a41c449a2a6ab28f8efe87e0ff7112 160 SUPERFAMILY SSF55826 3 157 1.31E-35 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 LH59_17855 cfdcc492e6e0cc96be84cf80010cee52 381 Pfam PF13458 Periplasmic binding protein 28 369 5.8E-61 T 14-10-2018 IPR028081 Leucine-binding protein domain LH59_17855 cfdcc492e6e0cc96be84cf80010cee52 381 SUPERFAMILY SSF53822 27 374 1.2E-91 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_17855 cfdcc492e6e0cc96be84cf80010cee52 381 Gene3D G3DSA:3.40.50.2300 148 276 3.4E-98 T 14-10-2018 LH59_17855 cfdcc492e6e0cc96be84cf80010cee52 381 Gene3D G3DSA:3.40.50.2300 29 343 3.4E-98 T 14-10-2018 LH59_02870 5acc71cd7cf13e8f5fc9cafe7bd9aa00 408 Pfam PF01960 ArgJ family 22 408 8.2E-139 T 14-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 LH59_02870 5acc71cd7cf13e8f5fc9cafe7bd9aa00 408 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 25 406 3.0E-174 T 14-10-2018 LH59_02870 5acc71cd7cf13e8f5fc9cafe7bd9aa00 408 SUPERFAMILY SSF56266 16 405 1.28E-134 T 14-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 LH59_02870 5acc71cd7cf13e8f5fc9cafe7bd9aa00 408 Gene3D G3DSA:3.10.20.340 279 408 1.2E-40 T 14-10-2018 LH59_02870 5acc71cd7cf13e8f5fc9cafe7bd9aa00 408 Gene3D G3DSA:3.60.70.12 10 278 5.8E-88 T 14-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 LH59_02870 5acc71cd7cf13e8f5fc9cafe7bd9aa00 408 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 12 408 9.5E-118 T 14-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 LH59_02870 5acc71cd7cf13e8f5fc9cafe7bd9aa00 408 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 408 155.428 T 14-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 LH59_26365 587213ec70ddea8301a891b0e41119f6 528 Pfam PF01551 Peptidase family M23 429 522 1.4E-25 T 14-10-2018 IPR016047 Peptidase M23 LH59_26365 587213ec70ddea8301a891b0e41119f6 528 SUPERFAMILY SSF51261 405 526 5.18E-43 T 14-10-2018 IPR011055 Duplicated hybrid motif LH59_26365 587213ec70ddea8301a891b0e41119f6 528 Gene3D G3DSA:2.70.70.10 401 527 8.5E-33 T 14-10-2018 IPR011055 Duplicated hybrid motif LH59_10510 e7ef0e69fbc15185d4943eed77a93a57 221 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 103 121 2.3E-65 T 14-10-2018 LH59_10510 e7ef0e69fbc15185d4943eed77a93a57 221 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 78 101 2.3E-65 T 14-10-2018 LH59_10510 e7ef0e69fbc15185d4943eed77a93a57 221 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 134 157 2.3E-65 T 14-10-2018 LH59_10510 e7ef0e69fbc15185d4943eed77a93a57 221 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 194 217 2.3E-65 T 14-10-2018 LH59_10510 e7ef0e69fbc15185d4943eed77a93a57 221 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 157 176 2.3E-65 T 14-10-2018 LH59_10510 e7ef0e69fbc15185d4943eed77a93a57 221 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 29 50 2.3E-65 T 14-10-2018 LH59_10510 e7ef0e69fbc15185d4943eed77a93a57 221 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 55 72 2.3E-65 T 14-10-2018 LH59_10510 e7ef0e69fbc15185d4943eed77a93a57 221 PIRSF PIRSF002764 1 221 1.7E-73 T 14-10-2018 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria LH59_10510 e7ef0e69fbc15185d4943eed77a93a57 221 Pfam PF03379 CcmB protein 6 218 5.1E-63 T 14-10-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 LH59_10510 e7ef0e69fbc15185d4943eed77a93a57 221 TIGRFAM TIGR01190 ccmB: heme exporter protein CcmB 9 217 5.2E-62 T 14-10-2018 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria LH59_02020 575a9890705a43460e9a17eacbb98528 301 SUPERFAMILY SSF52943 3 301 1.44E-88 T 14-10-2018 IPR035968 ATP synthase, F1 complex, gamma subunit superfamily GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 LH59_02020 575a9890705a43460e9a17eacbb98528 301 Gene3D G3DSA:1.10.287.80 6 297 2.7E-99 T 14-10-2018 LH59_02020 575a9890705a43460e9a17eacbb98528 301 Pfam PF00231 ATP synthase 4 300 3.1E-89 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 LH59_02020 575a9890705a43460e9a17eacbb98528 301 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 301 34.279 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 LH59_02020 575a9890705a43460e9a17eacbb98528 301 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 287 300 - T 14-10-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 LH59_02020 575a9890705a43460e9a17eacbb98528 301 PRINTS PR00126 ATP synthase gamma subunit signature 279 300 1.0E-33 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 LH59_02020 575a9890705a43460e9a17eacbb98528 301 PRINTS PR00126 ATP synthase gamma subunit signature 248 267 1.0E-33 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 LH59_02020 575a9890705a43460e9a17eacbb98528 301 PRINTS PR00126 ATP synthase gamma subunit signature 166 183 1.0E-33 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 LH59_02020 575a9890705a43460e9a17eacbb98528 301 PRINTS PR00126 ATP synthase gamma subunit signature 73 92 1.0E-33 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 LH59_02020 575a9890705a43460e9a17eacbb98528 301 Gene3D G3DSA:3.40.1380.10 61 220 2.7E-99 T 14-10-2018 LH59_02020 575a9890705a43460e9a17eacbb98528 301 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 1 301 8.8E-96 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 LH59_03325 05b75e5299c4a53f177ae95e2926ff45 182 PIRSF PIRSF016183 2 182 3.7E-61 T 14-10-2018 IPR006839 Ribosome-associated, YjgA LH59_03325 05b75e5299c4a53f177ae95e2926ff45 182 Pfam PF04751 Protein of unknown function (DUF615) 20 178 7.6E-51 T 14-10-2018 IPR006839 Ribosome-associated, YjgA LH59_03325 05b75e5299c4a53f177ae95e2926ff45 182 Hamap MF_00765 UPF0307 protein YjgA [yjgA]. 11 182 21.449 T 14-10-2018 IPR006839 Ribosome-associated, YjgA LH59_03325 05b75e5299c4a53f177ae95e2926ff45 182 SUPERFAMILY SSF158710 30 180 1.15E-42 T 14-10-2018 IPR023153 PSPTO4464-like domain superfamily LH59_03325 05b75e5299c4a53f177ae95e2926ff45 182 Gene3D G3DSA:1.10.60.30 107 182 1.1E-18 T 14-10-2018 LH59_03325 05b75e5299c4a53f177ae95e2926ff45 182 Gene3D G3DSA:1.10.60.30 30 105 4.5E-27 T 14-10-2018 LH59_20320 0b8eaefe04014f7e83b2b67d8240b56f 484 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 2 483 3.8E-147 T 14-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 LH59_20320 0b8eaefe04014f7e83b2b67d8240b56f 484 SUPERFAMILY SSF47323 333 482 6.28E-32 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 LH59_20320 0b8eaefe04014f7e83b2b67d8240b56f 484 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 225 246 6.1E-28 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 LH59_20320 0b8eaefe04014f7e83b2b67d8240b56f 484 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 61 70 6.1E-28 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 LH59_20320 0b8eaefe04014f7e83b2b67d8240b56f 484 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 194 212 6.1E-28 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 LH59_20320 0b8eaefe04014f7e83b2b67d8240b56f 484 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 25 36 6.1E-28 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 LH59_20320 0b8eaefe04014f7e83b2b67d8240b56f 484 SUPERFAMILY SSF52374 2 331 3.38E-83 T 14-10-2018 LH59_20320 0b8eaefe04014f7e83b2b67d8240b56f 484 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 2 483 36.861 T 14-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 LH59_20320 0b8eaefe04014f7e83b2b67d8240b56f 484 SMART SM00840 359 414 5.0E-23 T 14-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 LH59_20320 0b8eaefe04014f7e83b2b67d8240b56f 484 Gene3D G3DSA:1.20.120.640 323 484 3.2E-38 T 14-10-2018 LH59_20320 0b8eaefe04014f7e83b2b67d8240b56f 484 Pfam PF09190 DALR domain 359 413 8.6E-16 T 14-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 LH59_20320 0b8eaefe04014f7e83b2b67d8240b56f 484 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 15 330 1.6E-109 T 14-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 LH59_20320 0b8eaefe04014f7e83b2b67d8240b56f 484 Gene3D G3DSA:3.40.50.620 1 322 5.9E-118 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LH59_04060 7b8fa9b2183c6a727ff0d0bca28d83fd 274 Pfam PF03799 Cell division protein FtsQ 114 245 1.6E-23 T 14-10-2018 IPR005548 Cell division protein FtsQ/DivIB LH59_04060 7b8fa9b2183c6a727ff0d0bca28d83fd 274 Pfam PF08478 POTRA domain, FtsQ-type 52 110 8.2E-14 T 14-10-2018 IPR013685 POTRA domain, FtsQ-type LH59_04060 7b8fa9b2183c6a727ff0d0bca28d83fd 274 Gene3D G3DSA:3.40.50.11690 111 258 1.3E-38 T 14-10-2018 LH59_04060 7b8fa9b2183c6a727ff0d0bca28d83fd 274 Gene3D G3DSA:3.10.20.310 40 110 1.3E-16 T 14-10-2018 LH59_04060 7b8fa9b2183c6a727ff0d0bca28d83fd 274 Hamap MF_00911 Cell division protein FtsQ [ftsQ]. 7 253 24.722 T 14-10-2018 IPR026579 Cell division protein FtsQ GO:0090529 LH59_20730 243ead9ae0f586459cfff99a613141f6 865 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 323 353 2.7E-7 T 14-10-2018 IPR013425 Autotransporter-associated beta strand repeat LH59_20730 243ead9ae0f586459cfff99a613141f6 865 PRINTS PR00723 Subtilisin serine protease family (S8) signature 231 247 1.2E-6 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related LH59_20730 243ead9ae0f586459cfff99a613141f6 865 PRINTS PR00723 Subtilisin serine protease family (S8) signature 12 31 1.2E-6 T 14-10-2018 IPR015500 Peptidase S8, subtilisin-related LH59_20730 243ead9ae0f586459cfff99a613141f6 865 SUPERFAMILY SSF52743 9 289 1.57E-36 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 LH59_20730 243ead9ae0f586459cfff99a613141f6 865 Gene3D G3DSA:2.40.128.130 548 864 1.7E-63 T 14-10-2018 IPR036709 Autotransporter beta-domain superfamily LH59_20730 243ead9ae0f586459cfff99a613141f6 865 Pfam PF03797 Autotransporter beta-domain 593 843 8.5E-43 T 14-10-2018 IPR005546 Autotransporter beta-domain LH59_20730 243ead9ae0f586459cfff99a613141f6 865 Gene3D G3DSA:3.40.50.200 3 289 5.1E-38 T 14-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 LH59_20730 243ead9ae0f586459cfff99a613141f6 865 SUPERFAMILY SSF103515 555 864 8.24E-56 T 14-10-2018 IPR036709 Autotransporter beta-domain superfamily LH59_20730 243ead9ae0f586459cfff99a613141f6 865 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 232 242 - T 14-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site LH59_20730 243ead9ae0f586459cfff99a613141f6 865 SMART SM00869 590 853 8.1E-34 T 14-10-2018 IPR005546 Autotransporter beta-domain LH59_20730 243ead9ae0f586459cfff99a613141f6 865 Pfam PF00082 Subtilase family 12 279 3.6E-27 T 14-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 LH59_20730 243ead9ae0f586459cfff99a613141f6 865 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 554 864 5.6E-25 T 14-10-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 LH59_11310 a92c69e9edf46b2887b16409669c3fd1 329 Gene3D G3DSA:3.30.1330.60 113 299 2.2E-56 T 14-10-2018 IPR036737 OmpA-like domain superfamily LH59_11310 a92c69e9edf46b2887b16409669c3fd1 329 Pfam PF00691 OmpA family 166 254 3.7E-11 T 14-10-2018 IPR006665 OmpA-like domain LH59_11310 a92c69e9edf46b2887b16409669c3fd1 329 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 13 65 5.1E-19 T 14-10-2018 IPR025713 Motility protein B, N-terminal domain LH59_11310 a92c69e9edf46b2887b16409669c3fd1 329 SUPERFAMILY SSF103088 159 270 1.83E-19 T 14-10-2018 IPR036737 OmpA-like domain superfamily LH59_06045 485f28b6a937b7e4646a239b943aef8c 391 Gene3D G3DSA:2.40.30.170 49 301 6.4E-99 T 14-10-2018 LH59_06045 485f28b6a937b7e4646a239b943aef8c 391 Gene3D G3DSA:2.40.50.100 61 205 6.4E-99 T 14-10-2018 LH59_06045 485f28b6a937b7e4646a239b943aef8c 391 Gene3D G3DSA:1.10.287.470 96 169 6.4E-99 T 14-10-2018 LH59_06045 485f28b6a937b7e4646a239b943aef8c 391 SUPERFAMILY SSF111369 50 297 1.83E-74 T 14-10-2018 LH59_06045 485f28b6a937b7e4646a239b943aef8c 391 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 39 372 1.1E-76 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 LH59_06045 485f28b6a937b7e4646a239b943aef8c 391 Gene3D G3DSA:2.40.420.20 302 370 6.4E-99 T 14-10-2018 LH59_06045 485f28b6a937b7e4646a239b943aef8c 391 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 60 291 1.0E-11 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain LH59_01890 89e307bdc4f27ce670d6e9f16df982e5 308 Gene3D G3DSA:1.10.10.10 4 91 9.2E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_01890 89e307bdc4f27ce670d6e9f16df982e5 308 SUPERFAMILY SSF53850 93 294 2.81E-27 T 14-10-2018 LH59_01890 89e307bdc4f27ce670d6e9f16df982e5 308 SUPERFAMILY SSF46785 5 87 5.1E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_01890 89e307bdc4f27ce670d6e9f16df982e5 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 7.0E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_01890 89e307bdc4f27ce670d6e9f16df982e5 308 Gene3D G3DSA:3.40.190.290 95 279 2.4E-15 T 14-10-2018 LH59_01890 89e307bdc4f27ce670d6e9f16df982e5 308 Pfam PF03466 LysR substrate binding domain 92 293 8.2E-26 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_18225 794ae85f4096aafce4641da972517b01 195 SUPERFAMILY SSF55811 13 180 2.44E-49 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 LH59_18225 794ae85f4096aafce4641da972517b01 195 Pfam PF00293 NUDIX domain 49 160 4.9E-15 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 LH59_18225 794ae85f4096aafce4641da972517b01 195 Gene3D G3DSA:3.90.79.10 7 187 5.7E-54 T 14-10-2018 LH59_25375 b33e52e634351548725fa69f49dd1787 192 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 73 171 1.6E-23 T 14-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 LH59_25375 b33e52e634351548725fa69f49dd1787 192 Gene3D G3DSA:3.40.80.10 9 182 2.3E-54 T 14-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 LH59_25375 b33e52e634351548725fa69f49dd1787 192 SMART SM00644 22 170 1.8E-43 T 14-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 LH59_25375 b33e52e634351548725fa69f49dd1787 192 SUPERFAMILY SSF55846 16 180 7.46E-60 T 14-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 LH59_12385 bb397662b874d178cbc17f5e570098a5 300 SUPERFAMILY SSF46785 3 87 9.09E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_12385 bb397662b874d178cbc17f5e570098a5 300 Gene3D G3DSA:1.10.10.10 2 92 3.0E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_12385 bb397662b874d178cbc17f5e570098a5 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 8.0E-11 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_12385 bb397662b874d178cbc17f5e570098a5 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 8.0E-11 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_12385 bb397662b874d178cbc17f5e570098a5 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 8.0E-11 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_12385 bb397662b874d178cbc17f5e570098a5 300 SUPERFAMILY SSF53850 88 298 1.86E-33 T 14-10-2018 LH59_12385 bb397662b874d178cbc17f5e570098a5 300 Gene3D G3DSA:3.40.190.10 164 273 7.5E-60 T 14-10-2018 LH59_12385 bb397662b874d178cbc17f5e570098a5 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 2.2E-21 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_12385 bb397662b874d178cbc17f5e570098a5 300 Gene3D G3DSA:3.40.190.10 93 291 7.5E-60 T 14-10-2018 LH59_12385 bb397662b874d178cbc17f5e570098a5 300 Pfam PF03466 LysR substrate binding domain 88 297 4.0E-35 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_27535 9a3c5f7fb93c93fa2c48a7649f30561c 297 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 137 167 - T 14-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 LH59_27535 9a3c5f7fb93c93fa2c48a7649f30561c 297 SUPERFAMILY SSF51569 3 290 4.92E-76 T 14-10-2018 LH59_27535 9a3c5f7fb93c93fa2c48a7649f30561c 297 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 14 287 1.1E-65 T 14-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LH59_27535 9a3c5f7fb93c93fa2c48a7649f30561c 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 107 123 7.5E-16 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_27535 9a3c5f7fb93c93fa2c48a7649f30561c 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 40 61 7.5E-16 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_27535 9a3c5f7fb93c93fa2c48a7649f30561c 297 PRINTS PR00146 Dihydrodipicolinate synthase signature 132 149 7.5E-16 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_27535 9a3c5f7fb93c93fa2c48a7649f30561c 297 Gene3D G3DSA:3.20.20.70 1 291 1.8E-78 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_27535 9a3c5f7fb93c93fa2c48a7649f30561c 297 Pfam PF00701 Dihydrodipicolinate synthetase family 8 277 1.0E-52 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_27535 9a3c5f7fb93c93fa2c48a7649f30561c 297 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 7 289 43.084 T 14-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LH59_27535 9a3c5f7fb93c93fa2c48a7649f30561c 297 PIRSF PIRSF001365 3 297 3.8E-65 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_27535 9a3c5f7fb93c93fa2c48a7649f30561c 297 SMART SM01130 7 291 1.7E-86 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_27535 9a3c5f7fb93c93fa2c48a7649f30561c 297 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 43 60 - T 14-10-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LH59_13925 692dfe38801817cdfb6bc0c48fb33a39 708 Gene3D G3DSA:3.60.21.10 80 356 2.3E-13 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like LH59_13925 692dfe38801817cdfb6bc0c48fb33a39 708 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 540 700 8.0E-14 T 14-10-2018 LH59_13925 692dfe38801817cdfb6bc0c48fb33a39 708 SUPERFAMILY SSF56300 79 360 5.7E-24 T 14-10-2018 LH59_13925 692dfe38801817cdfb6bc0c48fb33a39 708 Gene3D G3DSA:2.60.120.200 521 706 4.6E-17 T 14-10-2018 LH59_13925 692dfe38801817cdfb6bc0c48fb33a39 708 SUPERFAMILY SSF49899 493 700 9.39E-19 T 14-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily LH59_13925 692dfe38801817cdfb6bc0c48fb33a39 708 Pfam PF00149 Calcineurin-like phosphoesterase 79 308 8.1E-8 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 LH59_15100 2302e4d3608d5435dde2c0eed6347196 236 SUPERFAMILY SSF52540 5 221 1.36E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_15100 2302e4d3608d5435dde2c0eed6347196 236 Gene3D G3DSA:3.40.50.300 3 224 3.0E-54 T 14-10-2018 LH59_15100 2302e4d3608d5435dde2c0eed6347196 236 Pfam PF00005 ABC transporter 22 164 3.7E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_15100 2302e4d3608d5435dde2c0eed6347196 236 SMART SM00382 31 214 8.6E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_15100 2302e4d3608d5435dde2c0eed6347196 236 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_01250 83acdb89ef376c976018168db4bafa91 718 Pfam PF00593 TonB dependent receptor 237 716 7.6E-69 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_01250 83acdb89ef376c976018168db4bafa91 718 Gene3D G3DSA:2.40.170.20 167 718 8.5E-141 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_01250 83acdb89ef376c976018168db4bafa91 718 Gene3D G3DSA:2.170.130.10 29 166 5.4E-36 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily LH59_01250 83acdb89ef376c976018168db4bafa91 718 SUPERFAMILY SSF56935 18 718 2.05E-134 T 14-10-2018 LH59_01250 83acdb89ef376c976018168db4bafa91 718 Pfam PF07715 TonB-dependent Receptor Plug Domain 49 156 5.1E-22 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_01250 83acdb89ef376c976018168db4bafa91 718 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 51 715 1.2E-128 T 14-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 LH59_13795 4b8b0089d8c9e8bfe6b8e31bd54a9ea8 399 Gene3D G3DSA:1.20.1250.20 6 393 1.1E-26 T 14-10-2018 LH59_13795 4b8b0089d8c9e8bfe6b8e31bd54a9ea8 399 Pfam PF07690 Major Facilitator Superfamily 18 326 2.2E-13 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_13795 4b8b0089d8c9e8bfe6b8e31bd54a9ea8 399 SUPERFAMILY SSF103473 6 395 6.54E-32 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_26335 8c67432cd6ffd5b96c07e3cdb9ebc8a7 637 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 137 602 1.3E-212 T 14-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 LH59_26335 8c67432cd6ffd5b96c07e3cdb9ebc8a7 637 Pfam PF13667 ThiC-associated domain 21 98 1.3E-31 T 14-10-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 LH59_26335 8c67432cd6ffd5b96c07e3cdb9ebc8a7 637 Gene3D G3DSA:3.20.20.540 221 534 4.9E-152 T 14-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 LH59_26335 8c67432cd6ffd5b96c07e3cdb9ebc8a7 637 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 137 603 99.115 T 14-10-2018 IPR037509 Phosphomethylpyrimidine synthase GO:0009228|GO:0016830 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 LH59_26335 8c67432cd6ffd5b96c07e3cdb9ebc8a7 637 Pfam PF01964 Radical SAM ThiC family 139 598 9.8E-198 T 14-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 LH59_03050 d02d3850d3f60e8ea108eb8e821a8f3f 434 SUPERFAMILY SSF51338 1 431 7.81E-26 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 LH59_03050 d02d3850d3f60e8ea108eb8e821a8f3f 434 Gene3D G3DSA:2.30.40.10 9 427 3.3E-89 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 LH59_03050 d02d3850d3f60e8ea108eb8e821a8f3f 434 Gene3D G3DSA:3.20.20.140 57 372 3.3E-89 T 14-10-2018 LH59_03050 d02d3850d3f60e8ea108eb8e821a8f3f 434 SUPERFAMILY SSF51556 56 364 6.09E-65 T 14-10-2018 IPR032466 Metal-dependent hydrolase LH59_03050 d02d3850d3f60e8ea108eb8e821a8f3f 434 Pfam PF01979 Amidohydrolase family 278 427 6.4E-7 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 LH59_27390 7b79410ef445aa3fca1423aead8a7d96 333 SUPERFAMILY SSF52540 40 283 5.31E-13 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_27390 7b79410ef445aa3fca1423aead8a7d96 333 Pfam PF13469 Sulfotransferase family 44 283 3.2E-15 T 14-10-2018 LH59_27390 7b79410ef445aa3fca1423aead8a7d96 333 Gene3D G3DSA:3.40.50.300 3 328 2.2E-23 T 14-10-2018 LH59_14215 89da6a1edc5c6488cbf88c325517a8ff 479 SUPERFAMILY SSF47384 244 321 2.55E-9 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 LH59_14215 89da6a1edc5c6488cbf88c325517a8ff 479 Gene3D G3DSA:3.30.565.10 326 477 2.2E-32 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_14215 89da6a1edc5c6488cbf88c325517a8ff 479 SMART SM00387 367 476 6.1E-28 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_14215 89da6a1edc5c6488cbf88c325517a8ff 479 Gene3D G3DSA:1.10.287.130 232 319 8.5E-18 T 14-10-2018 LH59_14215 89da6a1edc5c6488cbf88c325517a8ff 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 460 473 7.3E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_14215 89da6a1edc5c6488cbf88c325517a8ff 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 407 421 7.3E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_14215 89da6a1edc5c6488cbf88c325517a8ff 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 425 435 7.3E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_14215 89da6a1edc5c6488cbf88c325517a8ff 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 436 454 7.3E-13 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_14215 89da6a1edc5c6488cbf88c325517a8ff 479 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 368 474 2.4E-19 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_14215 89da6a1edc5c6488cbf88c325517a8ff 479 Pfam PF00512 His Kinase A (phospho-acceptor) domain 256 319 8.7E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_14215 89da6a1edc5c6488cbf88c325517a8ff 479 SMART SM00388 255 324 2.1E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_14215 89da6a1edc5c6488cbf88c325517a8ff 479 SUPERFAMILY SSF55874 325 474 3.01E-33 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_11375 9252fee4aaa9dc0575506209eaef957a 937 TIGRFAM TIGR03499 FlhF: flagellar biosynthesis protein FlhF 184 415 6.0E-58 T 14-10-2018 IPR020006 Flagellar biosynthesis protein FlhF GO:0003924|GO:0044781 LH59_11375 9252fee4aaa9dc0575506209eaef957a 937 SMART SM00962 327 522 9.8E-60 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 LH59_11375 9252fee4aaa9dc0575506209eaef957a 937 Gene3D G3DSA:1.20.120.1380 296 511 1.8E-50 T 14-10-2018 LH59_11375 9252fee4aaa9dc0575506209eaef957a 937 Pfam PF00448 SRP54-type protein, GTPase domain 329 520 8.7E-36 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 LH59_11375 9252fee4aaa9dc0575506209eaef957a 937 SMART SM00382 326 499 5.9E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_11375 9252fee4aaa9dc0575506209eaef957a 937 SUPERFAMILY SSF52540 327 520 5.68E-31 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_11375 9252fee4aaa9dc0575506209eaef957a 937 Gene3D G3DSA:3.40.50.300 322 510 1.8E-50 T 14-10-2018 LH59_04960 ae39e6c180dd90963685a0deb148b980 271 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 226 2.6E-18 T 14-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain LH59_04960 ae39e6c180dd90963685a0deb148b980 271 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 3 268 3.1E-103 T 14-10-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 LH59_04960 ae39e6c180dd90963685a0deb148b980 271 SUPERFAMILY SSF52540 1 269 2.06E-51 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_04960 ae39e6c180dd90963685a0deb148b980 271 PIRSF PIRSF003092 1 271 4.0E-91 T 14-10-2018 IPR025501 ATP binding protein MinD LH59_04960 ae39e6c180dd90963685a0deb148b980 271 Gene3D G3DSA:3.40.50.300 1 260 2.3E-68 T 14-10-2018 LH59_03900 3632d76480626af0e44e023600ec0069 256 Gene3D G3DSA:3.30.110.170 52 250 1.5E-18 T 14-10-2018 LH59_03900 3632d76480626af0e44e023600ec0069 256 Pfam PF04402 Protein of unknown function (DUF541) 51 252 1.2E-25 T 14-10-2018 IPR007497 Protein of unknown function DUF541 LH59_03900 3632d76480626af0e44e023600ec0069 256 Gene3D G3DSA:3.30.70.2970 62 166 1.5E-18 T 14-10-2018 LH59_27175 8663ef373507b529072f0ded4453260b 167 Pfam PF01475 Ferric uptake regulator family 27 145 1.1E-16 T 14-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 LH59_27175 8663ef373507b529072f0ded4453260b 167 Gene3D G3DSA:3.30.1490.190 100 167 7.3E-14 T 14-10-2018 LH59_27175 8663ef373507b529072f0ded4453260b 167 SUPERFAMILY SSF46785 20 150 8.92E-32 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_27175 8663ef373507b529072f0ded4453260b 167 Gene3D G3DSA:1.10.10.10 10 96 1.9E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_14525 19140156dd4e39f27aebd9d1699a2cbc 252 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 131 151 - T 14-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 LH59_14525 19140156dd4e39f27aebd9d1699a2cbc 252 Gene3D G3DSA:1.10.4030.30 74 204 5.7E-21 T 14-10-2018 LH59_14525 19140156dd4e39f27aebd9d1699a2cbc 252 SUPERFAMILY SSF54534 89 195 5.63E-23 T 14-10-2018 LH59_14525 19140156dd4e39f27aebd9d1699a2cbc 252 Gene3D G3DSA:3.10.50.40 93 194 5.7E-21 T 14-10-2018 LH59_14525 19140156dd4e39f27aebd9d1699a2cbc 252 Pfam PF00639 PPIC-type PPIASE domain 99 191 2.2E-18 T 14-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 LH59_11815 f56c066ad2d58c38007503ad019bc91a 207 Hamap MF_00165 Thymidylate kinase [tmk]. 6 203 28.609 T 14-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 LH59_11815 f56c066ad2d58c38007503ad019bc91a 207 SUPERFAMILY SSF52540 1 186 1.29E-49 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_11815 f56c066ad2d58c38007503ad019bc91a 207 Pfam PF02223 Thymidylate kinase 10 193 2.7E-45 T 14-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 LH59_11815 f56c066ad2d58c38007503ad019bc91a 207 Gene3D G3DSA:3.40.50.300 2 204 1.6E-61 T 14-10-2018 LH59_11815 f56c066ad2d58c38007503ad019bc91a 207 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 4 193 1.7E-47 T 14-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 LH59_24445 81ce0cae6c900f5c581ab955004e8570 566 Pfam PF03797 Autotransporter beta-domain 298 546 2.3E-67 T 14-10-2018 IPR005546 Autotransporter beta-domain LH59_24445 81ce0cae6c900f5c581ab955004e8570 566 SUPERFAMILY SSF51126 3 158 2.67E-13 T 14-10-2018 IPR011050 Pectin lyase fold/virulence factor LH59_24445 81ce0cae6c900f5c581ab955004e8570 566 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 78 566 4.0E-62 T 14-10-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 LH59_24445 81ce0cae6c900f5c581ab955004e8570 566 Gene3D G3DSA:2.40.128.130 283 566 2.7E-80 T 14-10-2018 IPR036709 Autotransporter beta-domain superfamily LH59_24445 81ce0cae6c900f5c581ab955004e8570 566 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 8 39 4.2E-5 T 14-10-2018 IPR013425 Autotransporter-associated beta strand repeat LH59_24445 81ce0cae6c900f5c581ab955004e8570 566 SMART SM00869 294 556 9.9E-57 T 14-10-2018 IPR005546 Autotransporter beta-domain LH59_24445 81ce0cae6c900f5c581ab955004e8570 566 SUPERFAMILY SSF103515 237 566 8.37E-75 T 14-10-2018 IPR036709 Autotransporter beta-domain superfamily LH59_17835 1110b630162cb6c6e6d63f77144a69ad 245 SUPERFAMILY SSF52540 7 240 4.11E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_17835 1110b630162cb6c6e6d63f77144a69ad 245 PIRSF PIRSF039137 4 242 5.1E-109 T 14-10-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 LH59_17835 1110b630162cb6c6e6d63f77144a69ad 245 Pfam PF00005 ABC transporter 25 169 2.7E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_17835 1110b630162cb6c6e6d63f77144a69ad 245 SMART SM00382 33 235 2.7E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_17835 1110b630162cb6c6e6d63f77144a69ad 245 Gene3D G3DSA:3.40.50.300 4 242 5.0E-64 T 14-10-2018 LH59_17835 1110b630162cb6c6e6d63f77144a69ad 245 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_06380 be18676ced0984d083b4be7eb2fb746e 107 Gene3D G3DSA:3.30.70.20 2 101 2.8E-31 T 14-10-2018 LH59_06380 be18676ced0984d083b4be7eb2fb746e 107 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site LH59_06380 be18676ced0984d083b4be7eb2fb746e 107 PRINTS PR00354 7Fe ferredoxin signature 9 19 1.7E-15 T 14-10-2018 IPR000813 7Fe ferredoxin GO:0009055 LH59_06380 be18676ced0984d083b4be7eb2fb746e 107 PRINTS PR00354 7Fe ferredoxin signature 35 52 1.7E-15 T 14-10-2018 IPR000813 7Fe ferredoxin GO:0009055 LH59_06380 be18676ced0984d083b4be7eb2fb746e 107 PRINTS PR00354 7Fe ferredoxin signature 19 29 1.7E-15 T 14-10-2018 IPR000813 7Fe ferredoxin GO:0009055 LH59_06380 be18676ced0984d083b4be7eb2fb746e 107 Pfam PF00037 4Fe-4S binding domain 34 56 1.7E-6 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain LH59_06380 be18676ced0984d083b4be7eb2fb746e 107 Pfam PF11953 Domain of unknown function (DUF3470) 67 107 5.8E-17 T 14-10-2018 IPR022569 Ferredoxin, C-terminal LH59_06380 be18676ced0984d083b4be7eb2fb746e 107 SUPERFAMILY SSF54862 1 98 3.77E-23 T 14-10-2018 LH59_19290 f82bd40aa284ebd5072e5f6226d2390d 107 Pfam PF04972 BON domain 37 104 4.0E-19 T 14-10-2018 IPR007055 BON domain LH59_19290 f82bd40aa284ebd5072e5f6226d2390d 107 SMART SM00749 42 105 1.5E-6 T 14-10-2018 IPR014004 Transport-associated and nodulation domain, bacteria LH59_12465 91352d4902b642480fa9391575b978b2 358 Gene3D G3DSA:3.40.50.300 1 238 9.0E-81 T 14-10-2018 LH59_12465 91352d4902b642480fa9391575b978b2 358 SMART SM00382 28 211 2.4E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_12465 91352d4902b642480fa9391575b978b2 358 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_12465 91352d4902b642480fa9391575b978b2 358 SUPERFAMILY SSF50331 253 356 1.19E-7 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal LH59_12465 91352d4902b642480fa9391575b978b2 358 Pfam PF00005 ABC transporter 19 161 2.5E-35 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_12465 91352d4902b642480fa9391575b978b2 358 SUPERFAMILY SSF52540 4 242 1.09E-88 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_12465 91352d4902b642480fa9391575b978b2 358 Pfam PF08402 TOBE domain 283 355 6.8E-10 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 LH59_15275 1fb18f3fad864d05b7b51fd8bcaa1bb7 271 SUPERFAMILY SSF46689 220 269 1.25E-7 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_15275 1fb18f3fad864d05b7b51fd8bcaa1bb7 271 SMART SM00342 184 266 2.8E-22 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_15275 1fb18f3fad864d05b7b51fd8bcaa1bb7 271 SUPERFAMILY SSF51215 32 151 3.4E-18 T 14-10-2018 IPR037923 Transcription regulator HTH-like LH59_15275 1fb18f3fad864d05b7b51fd8bcaa1bb7 271 Gene3D G3DSA:1.10.10.60 169 271 3.3E-25 T 14-10-2018 LH59_15275 1fb18f3fad864d05b7b51fd8bcaa1bb7 271 SUPERFAMILY SSF46689 168 215 1.7E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_15275 1fb18f3fad864d05b7b51fd8bcaa1bb7 271 Pfam PF12833 Helix-turn-helix domain 190 268 1.6E-17 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_15275 1fb18f3fad864d05b7b51fd8bcaa1bb7 271 Pfam PF02311 AraC-like ligand binding domain 21 148 1.8E-23 T 14-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 LH59_02040 2d36960fdbd407c08fa0a96f367c4c9f 357 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 143 159 - T 14-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 LH59_02040 2d36960fdbd407c08fa0a96f367c4c9f 357 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 7 351 3.0E-130 T 14-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 LH59_02040 2d36960fdbd407c08fa0a96f367c4c9f 357 SUPERFAMILY SSF51726 5 354 1.13E-115 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 LH59_02040 2d36960fdbd407c08fa0a96f367c4c9f 357 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 11 349 1.9E-125 T 14-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 LH59_02040 2d36960fdbd407c08fa0a96f367c4c9f 357 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 24 33 - T 14-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 LH59_02040 2d36960fdbd407c08fa0a96f367c4c9f 357 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 8 352 48.623 T 14-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 LH59_02040 2d36960fdbd407c08fa0a96f367c4c9f 357 Gene3D G3DSA:3.20.20.210 1 357 6.8E-151 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 LH59_17210 a27028a1a5d42ad5d90eeefa88d86589 399 Gene3D G3DSA:3.90.1150.10 8 395 1.4E-164 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_17210 a27028a1a5d42ad5d90eeefa88d86589 399 Gene3D G3DSA:3.40.640.10 63 303 1.4E-164 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_17210 a27028a1a5d42ad5d90eeefa88d86589 399 PRINTS PR00799 Aspartate aminotransferase signature 276 301 1.0E-39 T 14-10-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 LH59_17210 a27028a1a5d42ad5d90eeefa88d86589 399 PRINTS PR00799 Aspartate aminotransferase signature 209 221 1.0E-39 T 14-10-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 LH59_17210 a27028a1a5d42ad5d90eeefa88d86589 399 PRINTS PR00799 Aspartate aminotransferase signature 178 197 1.0E-39 T 14-10-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 LH59_17210 a27028a1a5d42ad5d90eeefa88d86589 399 PRINTS PR00799 Aspartate aminotransferase signature 344 362 1.0E-39 T 14-10-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 LH59_17210 a27028a1a5d42ad5d90eeefa88d86589 399 SUPERFAMILY SSF53383 2 398 2.04E-121 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_17210 a27028a1a5d42ad5d90eeefa88d86589 399 Pfam PF00155 Aminotransferase class I and II 31 394 2.1E-79 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LH59_17210 a27028a1a5d42ad5d90eeefa88d86589 399 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 246 259 - T 14-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 LH59_13495 3213c5bb3b06b7d68fddb984ab7b6006 264 Gene3D G3DSA:3.40.30.10 40 181 3.5E-5 T 14-10-2018 LH59_13495 3213c5bb3b06b7d68fddb984ab7b6006 264 SUPERFAMILY SSF52833 40 150 7.91E-11 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_13495 3213c5bb3b06b7d68fddb984ab7b6006 264 Pfam PF05988 Bacterial protein of unknown function (DUF899) 1 253 5.9E-92 T 14-10-2018 IPR010296 Protein of unknown function DUF899, thioredoxin-like LH59_11695 5e8106067ae51c586776a403addedda3 365 TIGRFAM TIGR01853 lipid_A_lpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 35 358 4.3E-105 T 14-10-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 LH59_11695 5e8106067ae51c586776a403addedda3 365 SUPERFAMILY SSF51161 49 345 1.67E-78 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily LH59_11695 5e8106067ae51c586776a403addedda3 365 Gene3D G3DSA:3.40.1390.10 27 121 1.2E-22 T 14-10-2018 LH59_11695 5e8106067ae51c586776a403addedda3 365 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 155 183 - T 14-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 LH59_11695 5e8106067ae51c586776a403addedda3 365 Hamap MF_00523 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [lpxD]. 9 355 36.197 T 14-10-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 LH59_11695 5e8106067ae51c586776a403addedda3 365 Pfam PF04613 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD 39 112 1.8E-21 T 14-10-2018 IPR020573 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region GO:0009245|GO:0016747 LH59_11695 5e8106067ae51c586776a403addedda3 365 Gene3D G3DSA:2.160.10.10 124 337 4.3E-60 T 14-10-2018 LH59_11695 5e8106067ae51c586776a403addedda3 365 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 251 286 5.9E-5 T 14-10-2018 IPR001451 Hexapeptide repeat LH59_11695 5e8106067ae51c586776a403addedda3 365 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 171 204 1.2E-6 T 14-10-2018 IPR001451 Hexapeptide repeat LH59_11695 5e8106067ae51c586776a403addedda3 365 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 134 168 1.1E-9 T 14-10-2018 IPR001451 Hexapeptide repeat LH59_11695 5e8106067ae51c586776a403addedda3 365 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 288 321 0.011 T 14-10-2018 IPR001451 Hexapeptide repeat LH59_11695 5e8106067ae51c586776a403addedda3 365 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 229 245 0.038 T 14-10-2018 IPR001451 Hexapeptide repeat LH59_23635 81813efcb68479e790abaf909c24ba97 332 Pfam PF03741 Integral membrane protein TerC family 82 289 5.8E-55 T 14-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 LH59_23635 81813efcb68479e790abaf909c24ba97 332 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 16 321 1.5E-122 T 14-10-2018 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 LH59_23750 1ce110457391401c041c8870a503ca62 376 Pfam PF09594 Glycosyltransferase family 87 5 193 8.2E-5 T 14-10-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 LH59_23750 1ce110457391401c041c8870a503ca62 376 PRINTS PR01036 Tetracycline resistance protein TetB signature 97 117 6.5E-5 T 14-10-2018 LH59_23750 1ce110457391401c041c8870a503ca62 376 PRINTS PR01036 Tetracycline resistance protein TetB signature 127 151 6.5E-5 T 14-10-2018 LH59_23750 1ce110457391401c041c8870a503ca62 376 PRINTS PR01036 Tetracycline resistance protein TetB signature 6 30 6.5E-5 T 14-10-2018 LH59_23750 1ce110457391401c041c8870a503ca62 376 SUPERFAMILY SSF103473 5 370 3.27E-32 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_23750 1ce110457391401c041c8870a503ca62 376 Gene3D G3DSA:1.20.1720.10 5 373 9.7E-59 T 14-10-2018 LH59_23750 1ce110457391401c041c8870a503ca62 376 Pfam PF07690 Major Facilitator Superfamily 16 337 4.3E-22 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_09915 3663ffff7cb522402a3ab9b48cd23979 445 Pfam PF00535 Glycosyl transferase family 2 78 245 2.5E-34 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 LH59_09915 3663ffff7cb522402a3ab9b48cd23979 445 Gene3D G3DSA:3.90.550.10 71 287 2.2E-45 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases LH59_09915 3663ffff7cb522402a3ab9b48cd23979 445 SUPERFAMILY SSF53448 68 341 2.3E-64 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases LH59_09915 3663ffff7cb522402a3ab9b48cd23979 445 TIGRFAM TIGR03937 PgaC_IcaA: poly-beta-1,6 N-acetyl-D-glucosamine synthase 31 438 4.8E-193 T 14-10-2018 IPR023853 Poly-beta-1,6 N-acetyl-D-glucosamine synthase PgaC/IcaA GO:0008375|GO:0043708 LH59_09470 2d2eba197338375feabb082b2ef62c12 311 PRINTS PR00111 Alpha/beta hydrolase fold signature 137 150 9.8E-7 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_09470 2d2eba197338375feabb082b2ef62c12 311 PRINTS PR00111 Alpha/beta hydrolase fold signature 76 91 9.8E-7 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_09470 2d2eba197338375feabb082b2ef62c12 311 Gene3D G3DSA:3.40.50.1820 20 310 3.5E-55 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_09470 2d2eba197338375feabb082b2ef62c12 311 Pfam PF00561 alpha/beta hydrolase fold 51 293 1.2E-27 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_09470 2d2eba197338375feabb082b2ef62c12 311 SUPERFAMILY SSF53474 22 308 1.58E-66 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_16065 79281c5474aa4edc563b26eb63d1776d 640 Pfam PF06276 Ferric iron reductase FhuF-like transporter 458 622 5.1E-26 T 14-10-2018 IPR022770 Ferric iron reductase FhuF domain LH59_16065 79281c5474aa4edc563b26eb63d1776d 640 Gene3D G3DSA:1.10.510.40 420 634 2.1E-21 T 14-10-2018 LH59_16065 79281c5474aa4edc563b26eb63d1776d 640 Pfam PF04183 IucA / IucC family 192 430 5.1E-56 T 14-10-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0019290 LH59_15610 050be3ce97afd45c7ebf8faf68aeb37b 148 SUPERFAMILY SSF102462 14 148 1.67E-27 T 14-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 LH59_15610 050be3ce97afd45c7ebf8faf68aeb37b 148 Gene3D G3DSA:3.40.1490.10 12 147 2.9E-14 T 14-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 LH59_15610 050be3ce97afd45c7ebf8faf68aeb37b 148 Pfam PF09391 Protein of unknown function (DUF2000) 14 148 1.4E-32 T 14-10-2018 IPR018988 Protein of unknown function DUF2000 LH59_22410 e2b28b3bfc0839fe51064550923cc848 398 Gene3D G3DSA:2.30.40.10 345 366 8.0E-7 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 LH59_22410 e2b28b3bfc0839fe51064550923cc848 398 SUPERFAMILY SSF51556 60 349 3.66E-13 T 14-10-2018 IPR032466 Metal-dependent hydrolase LH59_22410 e2b28b3bfc0839fe51064550923cc848 398 Pfam PF01979 Amidohydrolase family 285 366 5.1E-6 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 LH59_22410 e2b28b3bfc0839fe51064550923cc848 398 Gene3D G3DSA:3.20.20.140 319 344 8.0E-7 T 14-10-2018 LH59_22410 e2b28b3bfc0839fe51064550923cc848 398 SUPERFAMILY SSF51338 17 381 2.62E-7 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 LH59_22410 e2b28b3bfc0839fe51064550923cc848 398 PIRSF PIRSF038971 11 383 1.5E-105 T 14-10-2018 IPR012696 Phosphonate metabolism PhnM GO:0019700 KEGG: 00440+3.6.1.63|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 LH59_09050 a4e4877093f5715406fb3a10d111e28d 308 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 45 260 2.6E-33 T 14-10-2018 IPR008775 Phytanoyl-CoA dioxygenase LH59_09050 a4e4877093f5715406fb3a10d111e28d 308 Gene3D G3DSA:2.60.120.620 1 304 3.4E-116 T 14-10-2018 LH59_09050 a4e4877093f5715406fb3a10d111e28d 308 TIGRFAM TIGR02408 ectoine_ThpD: ectoine hydroxylase 21 298 1.9E-152 T 14-10-2018 IPR012774 Ectoine dioxygenase GO:0016706|GO:0055114 LH59_09050 a4e4877093f5715406fb3a10d111e28d 308 SUPERFAMILY SSF51197 34 290 6.87E-66 T 14-10-2018 LH59_20025 12a164753bfc2206b934e6d008e4cd80 220 Gene3D G3DSA:1.10.10.10 99 218 8.7E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_20025 12a164753bfc2206b934e6d008e4cd80 220 SUPERFAMILY SSF52172 3 175 1.27E-9 T 14-10-2018 IPR011006 CheY-like superfamily LH59_20025 12a164753bfc2206b934e6d008e4cd80 220 Pfam PF00196 Bacterial regulatory proteins, luxR family 146 199 5.4E-16 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_20025 12a164753bfc2206b934e6d008e4cd80 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 188 1.1E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_20025 12a164753bfc2206b934e6d008e4cd80 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 146 160 1.1E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_20025 12a164753bfc2206b934e6d008e4cd80 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 176 1.1E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_20025 12a164753bfc2206b934e6d008e4cd80 220 SMART SM00421 143 200 6.6E-18 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_20025 12a164753bfc2206b934e6d008e4cd80 220 SUPERFAMILY SSF46894 128 206 6.8E-20 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LH59_25275 24bb6a3cc76c60d772ebc22132d4bcfb 324 PIRSF PIRSF017082 1 323 4.7E-82 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_25275 24bb6a3cc76c60d772ebc22132d4bcfb 324 Gene3D G3DSA:3.40.190.150 30 314 1.1E-104 T 14-10-2018 LH59_25275 24bb6a3cc76c60d772ebc22132d4bcfb 324 SUPERFAMILY SSF53850 31 279 4.34E-11 T 14-10-2018 LH59_25275 24bb6a3cc76c60d772ebc22132d4bcfb 324 Gene3D G3DSA:3.40.190.10 126 249 1.1E-104 T 14-10-2018 LH59_25275 24bb6a3cc76c60d772ebc22132d4bcfb 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 320 2.1E-78 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_13620 a12b690426b71574cc332086ef92c8a0 337 Pfam PF00005 ABC transporter 27 184 3.5E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_13620 a12b690426b71574cc332086ef92c8a0 337 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 236 322 3.8E-20 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_13620 a12b690426b71574cc332086ef92c8a0 337 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_13620 a12b690426b71574cc332086ef92c8a0 337 SUPERFAMILY SSF52540 6 256 9.97E-68 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_13620 a12b690426b71574cc332086ef92c8a0 337 Gene3D G3DSA:3.40.50.300 4 336 4.7E-97 T 14-10-2018 LH59_13620 a12b690426b71574cc332086ef92c8a0 337 SMART SM00382 35 234 5.6E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_13620 a12b690426b71574cc332086ef92c8a0 337 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 303 4.4E-18 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_20245 7feb79a2eb297204f943353f60d1c01a 944 SUPERFAMILY SSF52172 825 939 3.27E-34 T 14-10-2018 IPR011006 CheY-like superfamily LH59_20245 7feb79a2eb297204f943353f60d1c01a 944 Pfam PF00072 Response regulator receiver domain 827 934 3.8E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_20245 7feb79a2eb297204f943353f60d1c01a 944 SMART SM00448 825 936 3.3E-32 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_20245 7feb79a2eb297204f943353f60d1c01a 944 SUPERFAMILY SSF47384 449 529 4.71E-18 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 LH59_20245 7feb79a2eb297204f943353f60d1c01a 944 Gene3D G3DSA:3.30.565.10 528 697 8.5E-39 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_20245 7feb79a2eb297204f943353f60d1c01a 944 SUPERFAMILY SSF55874 519 690 3.93E-38 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_20245 7feb79a2eb297204f943353f60d1c01a 944 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 576 691 3.5E-23 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_20245 7feb79a2eb297204f943353f60d1c01a 944 SMART SM00387 576 692 3.7E-32 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_20245 7feb79a2eb297204f943353f60d1c01a 944 PRINTS PR00344 Bacterial sensor protein C-terminal signature 652 670 1.8E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_20245 7feb79a2eb297204f943353f60d1c01a 944 PRINTS PR00344 Bacterial sensor protein C-terminal signature 635 645 1.8E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_20245 7feb79a2eb297204f943353f60d1c01a 944 PRINTS PR00344 Bacterial sensor protein C-terminal signature 676 689 1.8E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_20245 7feb79a2eb297204f943353f60d1c01a 944 PRINTS PR00344 Bacterial sensor protein C-terminal signature 617 631 1.8E-12 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_20245 7feb79a2eb297204f943353f60d1c01a 944 Gene3D G3DSA:1.10.287.130 439 527 1.1E-22 T 14-10-2018 LH59_20245 7feb79a2eb297204f943353f60d1c01a 944 Gene3D G3DSA:3.40.50.2300 822 944 8.9E-33 T 14-10-2018 LH59_20245 7feb79a2eb297204f943353f60d1c01a 944 SMART SM00388 464 529 1.2E-21 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_20245 7feb79a2eb297204f943353f60d1c01a 944 Pfam PF00512 His Kinase A (phospho-acceptor) domain 464 529 3.0E-17 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_27155 9dcd0d79d3b991395ec1eeb6c7e04acb 312 Gene3D G3DSA:3.40.50.1980 16 183 2.0E-48 T 14-10-2018 LH59_27155 9dcd0d79d3b991395ec1eeb6c7e04acb 312 Pfam PF01297 Zinc-uptake complex component A periplasmic 18 308 7.7E-84 T 14-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 LH59_27155 9dcd0d79d3b991395ec1eeb6c7e04acb 312 PRINTS PR00690 Adhesin family signature 276 295 3.8E-17 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 LH59_27155 9dcd0d79d3b991395ec1eeb6c7e04acb 312 PRINTS PR00690 Adhesin family signature 59 76 3.8E-17 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 LH59_27155 9dcd0d79d3b991395ec1eeb6c7e04acb 312 PRINTS PR00690 Adhesin family signature 15 33 3.8E-17 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 LH59_27155 9dcd0d79d3b991395ec1eeb6c7e04acb 312 PRINTS PR00690 Adhesin family signature 46 59 3.8E-17 T 14-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 LH59_27155 9dcd0d79d3b991395ec1eeb6c7e04acb 312 Gene3D G3DSA:3.40.50.1980 186 311 3.0E-47 T 14-10-2018 LH59_27155 9dcd0d79d3b991395ec1eeb6c7e04acb 312 PRINTS PR00691 Adhesin B signature 289 307 1.5E-14 T 14-10-2018 IPR006129 Adhesin B GO:0007155 LH59_27155 9dcd0d79d3b991395ec1eeb6c7e04acb 312 PRINTS PR00691 Adhesin B signature 15 36 1.5E-14 T 14-10-2018 IPR006129 Adhesin B GO:0007155 LH59_27155 9dcd0d79d3b991395ec1eeb6c7e04acb 312 PRINTS PR00691 Adhesin B signature 59 78 1.5E-14 T 14-10-2018 IPR006129 Adhesin B GO:0007155 LH59_27155 9dcd0d79d3b991395ec1eeb6c7e04acb 312 PRINTS PR00691 Adhesin B signature 40 58 1.5E-14 T 14-10-2018 IPR006129 Adhesin B GO:0007155 LH59_27155 9dcd0d79d3b991395ec1eeb6c7e04acb 312 SUPERFAMILY SSF53807 14 310 1.37E-89 T 14-10-2018 LH59_03820 76002c16b7edcbb3001558fd7beadcf4 140 Pfam PF03061 Thioesterase superfamily 23 107 6.1E-20 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 LH59_03820 76002c16b7edcbb3001558fd7beadcf4 140 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 13 128 5.3E-34 T 14-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 LH59_03820 76002c16b7edcbb3001558fd7beadcf4 140 TIGRFAM TIGR02799 thio_ybgC: tol-pal system-associated acyl-CoA thioesterase 11 133 2.2E-50 T 14-10-2018 IPR014166 Tol-Pal system-associated acyl-CoA thioesterase GO:0016790 LH59_03820 76002c16b7edcbb3001558fd7beadcf4 140 PIRSF PIRSF003230 2 140 9.3E-47 T 14-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 LH59_03820 76002c16b7edcbb3001558fd7beadcf4 140 SUPERFAMILY SSF54637 10 137 8.34E-44 T 14-10-2018 IPR029069 HotDog domain superfamily LH59_03820 76002c16b7edcbb3001558fd7beadcf4 140 Gene3D G3DSA:3.10.129.10 5 139 3.4E-44 T 14-10-2018 LH59_04100 ee2067d48135f2e9762ae24acad291f3 247 Pfam PF07729 FCD domain 86 207 4.4E-27 T 14-10-2018 IPR011711 GntR, C-terminal LH59_04100 ee2067d48135f2e9762ae24acad291f3 247 SMART SM00895 85 208 1.3E-21 T 14-10-2018 IPR011711 GntR, C-terminal LH59_04100 ee2067d48135f2e9762ae24acad291f3 247 SUPERFAMILY SSF46785 14 79 4.82E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_04100 ee2067d48135f2e9762ae24acad291f3 247 SMART SM00345 17 75 4.2E-8 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_04100 ee2067d48135f2e9762ae24acad291f3 247 Gene3D G3DSA:1.10.10.10 11 75 1.4E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_04100 ee2067d48135f2e9762ae24acad291f3 247 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 73 3.3E-12 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_04100 ee2067d48135f2e9762ae24acad291f3 247 SUPERFAMILY SSF48008 81 216 2.01E-27 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_04100 ee2067d48135f2e9762ae24acad291f3 247 Gene3D G3DSA:1.20.120.530 79 216 1.1E-28 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_08135 955cf0ddab3c176f8016fee6d643bd64 339 Gene3D G3DSA:3.30.540.10 2 197 2.8E-68 T 14-10-2018 LH59_08135 955cf0ddab3c176f8016fee6d643bd64 339 PIRSF PIRSF000904 1 338 4.8E-124 T 14-10-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 LH59_08135 955cf0ddab3c176f8016fee6d643bd64 339 SUPERFAMILY SSF56655 3 333 6.26E-117 T 14-10-2018 LH59_08135 955cf0ddab3c176f8016fee6d643bd64 339 Hamap MF_01855 Fructose-1,6-bisphosphatase class 1 [fbp]. 4 335 46.785 T 14-10-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 LH59_08135 955cf0ddab3c176f8016fee6d643bd64 339 Pfam PF00316 Fructose-1-6-bisphosphatase, N-terminal domain 5 196 3.8E-61 T 14-10-2018 IPR033391 Fructose-1-6-bisphosphatase class I, N-terminal KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 LH59_08135 955cf0ddab3c176f8016fee6d643bd64 339 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 207 234 1.0E-72 T 14-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 LH59_08135 955cf0ddab3c176f8016fee6d643bd64 339 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 66 92 1.0E-72 T 14-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 LH59_08135 955cf0ddab3c176f8016fee6d643bd64 339 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 181 204 1.0E-72 T 14-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 LH59_08135 955cf0ddab3c176f8016fee6d643bd64 339 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 150 173 1.0E-72 T 14-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 LH59_08135 955cf0ddab3c176f8016fee6d643bd64 339 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 29 56 1.0E-72 T 14-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 LH59_08135 955cf0ddab3c176f8016fee6d643bd64 339 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 309 334 1.0E-72 T 14-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 LH59_08135 955cf0ddab3c176f8016fee6d643bd64 339 Gene3D G3DSA:3.40.190.80 198 335 1.1E-53 T 14-10-2018 LH59_08135 955cf0ddab3c176f8016fee6d643bd64 339 PIRSF PIRSF500210 1 337 9.6E-127 T 14-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 LH59_15450 1575552e7a247cc71d50973c9fa7a72e 167 Pfam PF05638 Type VI secretion system effector, Hcp 5 139 3.8E-38 T 14-10-2018 IPR008514 Type VI secretion system effector, Hcp LH59_15450 1575552e7a247cc71d50973c9fa7a72e 167 TIGRFAM TIGR03344 VI_effect_Hcp1: type VI secretion system effector, Hcp1 family 15 146 3.2E-24 T 14-10-2018 IPR008514 Type VI secretion system effector, Hcp LH59_15450 1575552e7a247cc71d50973c9fa7a72e 167 SUPERFAMILY SSF141452 1 162 1.96E-43 T 14-10-2018 IPR036624 Hcp1-like superfamily LH59_15450 1575552e7a247cc71d50973c9fa7a72e 167 Gene3D G3DSA:2.30.110.20 1 167 1.0E-56 T 14-10-2018 IPR036624 Hcp1-like superfamily LH59_02060 5d1775f27d1472aa4469bf7cb42a6c2a 352 SUPERFAMILY SSF53383 12 350 9.18E-97 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_02060 5d1775f27d1472aa4469bf7cb42a6c2a 352 PIRSF PIRSF038940 10 352 1.6E-157 T 14-10-2018 IPR026273 Low specificity L-threonine aldolase GO:0004793|GO:0006567 KEGG: 00260+4.1.2.48 LH59_02060 5d1775f27d1472aa4469bf7cb42a6c2a 352 Pfam PF01212 Beta-eliminating lyase 13 299 7.1E-60 T 14-10-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 LH59_02060 5d1775f27d1472aa4469bf7cb42a6c2a 352 Gene3D G3DSA:3.90.1150.10 15 343 4.8E-134 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_02060 5d1775f27d1472aa4469bf7cb42a6c2a 352 Gene3D G3DSA:3.40.640.10 22 261 4.8E-134 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_18725 5dfadb26c0a8f7bdf4bba0dfb04a6388 355 SUPERFAMILY SSF53474 63 274 3.27E-35 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_18725 5dfadb26c0a8f7bdf4bba0dfb04a6388 355 Pfam PF10503 Esterase PHB depolymerase 75 279 6.6E-63 T 14-10-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 LH59_18725 5dfadb26c0a8f7bdf4bba0dfb04a6388 355 TIGRFAM TIGR01840 esterase_phb: esterase, PHB depolymerase family 86 277 7.5E-37 T 14-10-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 LH59_18725 5dfadb26c0a8f7bdf4bba0dfb04a6388 355 Gene3D G3DSA:3.40.50.1820 59 347 1.2E-40 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_16000 f1c262f27343f636f71365871a2b1f20 219 Gene3D G3DSA:3.40.30.10 5 198 1.7E-43 T 14-10-2018 LH59_16000 f1c262f27343f636f71365871a2b1f20 219 SUPERFAMILY SSF47616 80 214 3.69E-25 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily LH59_16000 f1c262f27343f636f71365871a2b1f20 219 SUPERFAMILY SSF52833 1 106 2.24E-16 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_16000 f1c262f27343f636f71365871a2b1f20 219 Pfam PF13417 Glutathione S-transferase, N-terminal domain 6 78 6.9E-11 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 LH59_16000 f1c262f27343f636f71365871a2b1f20 219 Pfam PF13410 Glutathione S-transferase, C-terminal domain 128 190 4.4E-8 T 14-10-2018 LH59_16000 f1c262f27343f636f71365871a2b1f20 219 Gene3D G3DSA:1.20.1050.10 83 194 1.7E-43 T 14-10-2018 LH59_15520 e5ec37e2ec21dfb2e8af1580aa24ddb6 958 Pfam PF05954 Phage late control gene D protein (GPD) 36 357 9.4E-65 T 14-10-2018 LH59_15520 e5ec37e2ec21dfb2e8af1580aa24ddb6 958 SUPERFAMILY SSF69279 269 428 4.25E-9 T 14-10-2018 LH59_15520 e5ec37e2ec21dfb2e8af1580aa24ddb6 958 Gene3D G3DSA:2.30.110.50 33 352 9.0E-59 T 14-10-2018 LH59_15520 e5ec37e2ec21dfb2e8af1580aa24ddb6 958 Gene3D G3DSA:3.30.1920.30 240 306 9.0E-59 T 14-10-2018 LH59_15520 e5ec37e2ec21dfb2e8af1580aa24ddb6 958 SUPERFAMILY SSF69255 440 534 2.88E-22 T 14-10-2018 LH59_15520 e5ec37e2ec21dfb2e8af1580aa24ddb6 958 Pfam PF13296 Putative type VI secretion system Rhs element Vgr 604 709 4.3E-31 T 14-10-2018 IPR028244 Putative type VI secretion system, Rhs element associated Vgr domain LH59_15520 e5ec37e2ec21dfb2e8af1580aa24ddb6 958 Gene3D G3DSA:3.55.50.10 105 205 9.0E-59 T 14-10-2018 LH59_15520 e5ec37e2ec21dfb2e8af1580aa24ddb6 958 SUPERFAMILY SSF69279 26 187 7.94E-38 T 14-10-2018 LH59_15520 e5ec37e2ec21dfb2e8af1580aa24ddb6 958 Gene3D G3DSA:2.40.50.230 431 538 2.5E-30 T 14-10-2018 IPR037026 Vgr protein, OB-fold domain superfamily LH59_15520 e5ec37e2ec21dfb2e8af1580aa24ddb6 958 Pfam PF10106 Uncharacterized protein conserved in bacteria (DUF2345) 772 928 5.6E-39 T 14-10-2018 IPR018769 Domain of unknown function DUF2345, Vgr C-terminal LH59_12585 d3ad14cd739d50aa26cc0415eea8a9ac 1207 Pfam PF01968 Hydantoinase/oxoprolinase 203 489 1.2E-114 T 14-10-2018 IPR002821 Hydantoinase A/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 LH59_12585 d3ad14cd739d50aa26cc0415eea8a9ac 1207 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 5 184 6.7E-60 T 14-10-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 LH59_12585 d3ad14cd739d50aa26cc0415eea8a9ac 1207 Pfam PF02538 Hydantoinase B/oxoprolinase 689 1206 1.6E-197 T 14-10-2018 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 LH59_04215 578c2de74403d60b20570ca6ec8ce219 796 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 149 796 5.0E-109 T 14-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 LH59_04215 578c2de74403d60b20570ca6ec8ce219 796 Gene3D G3DSA:2.170.130.10 124 254 8.3E-39 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily LH59_04215 578c2de74403d60b20570ca6ec8ce219 796 Gene3D G3DSA:2.40.170.20 255 796 2.0E-163 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_04215 578c2de74403d60b20570ca6ec8ce219 796 Pfam PF07715 TonB-dependent Receptor Plug Domain 147 247 1.1E-14 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_04215 578c2de74403d60b20570ca6ec8ce219 796 Pfam PF00593 TonB dependent receptor 332 795 1.5E-51 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_04215 578c2de74403d60b20570ca6ec8ce219 796 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 779 796 - T 14-10-2018 IPR010917 TonB-dependent receptor, conserved site LH59_04215 578c2de74403d60b20570ca6ec8ce219 796 Gene3D G3DSA:3.55.50.30 23 123 2.8E-19 T 14-10-2018 LH59_04215 578c2de74403d60b20570ca6ec8ce219 796 SUPERFAMILY SSF56935 110 796 1.85E-124 T 14-10-2018 LH59_04215 578c2de74403d60b20570ca6ec8ce219 796 SMART SM00965 54 105 1.0E-8 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 LH59_08565 eff8d9c0800213f1407082b57a7f2393 318 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 41 314 8.6E-73 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_08565 eff8d9c0800213f1407082b57a7f2393 318 PIRSF PIRSF017082 1 317 1.1E-67 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_08565 eff8d9c0800213f1407082b57a7f2393 318 Gene3D G3DSA:3.40.190.10 120 243 4.6E-103 T 14-10-2018 LH59_08565 eff8d9c0800213f1407082b57a7f2393 318 Gene3D G3DSA:3.40.190.150 24 308 4.6E-103 T 14-10-2018 LH59_08565 eff8d9c0800213f1407082b57a7f2393 318 SUPERFAMILY SSF53850 108 284 2.64E-14 T 14-10-2018 LH59_00690 0aa2ae6583ebd1723ba5013b4b6f9860 569 TIGRFAM TIGR00970 leuA_yeast: 2-isopropylmalate synthase 6 554 1.2E-238 T 14-10-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 LH59_00690 0aa2ae6583ebd1723ba5013b4b6f9860 569 SUPERFAMILY SSF110921 449 553 3.14E-33 T 14-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 LH59_00690 0aa2ae6583ebd1723ba5013b4b6f9860 569 Gene3D G3DSA:3.30.160.270 378 553 1.0E-59 T 14-10-2018 LH59_00690 0aa2ae6583ebd1723ba5013b4b6f9860 569 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 7 555 53.733 T 14-10-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 LH59_00690 0aa2ae6583ebd1723ba5013b4b6f9860 569 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 41 57 - T 14-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 LH59_00690 0aa2ae6583ebd1723ba5013b4b6f9860 569 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 244 257 - T 14-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 LH59_00690 0aa2ae6583ebd1723ba5013b4b6f9860 569 SMART SM00917 423 554 1.0E-31 T 14-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 LH59_00690 0aa2ae6583ebd1723ba5013b4b6f9860 569 SUPERFAMILY SSF89000 389 439 7.45E-15 T 14-10-2018 LH59_00690 0aa2ae6583ebd1723ba5013b4b6f9860 569 Gene3D G3DSA:3.20.20.70 16 377 7.3E-155 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_00690 0aa2ae6583ebd1723ba5013b4b6f9860 569 SUPERFAMILY SSF51569 23 331 1.21E-101 T 14-10-2018 LH59_00690 0aa2ae6583ebd1723ba5013b4b6f9860 569 Pfam PF00682 HMGL-like 34 312 5.6E-78 T 14-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 LH59_00690 0aa2ae6583ebd1723ba5013b4b6f9860 569 Pfam PF08502 LeuA allosteric (dimerisation) domain 423 552 2.6E-29 T 14-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 LH59_05015 f18b24bee2dd056fba282ad0364440bf 306 SUPERFAMILY SSF51735 1 260 1.31E-54 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_05015 f18b24bee2dd056fba282ad0364440bf 306 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 217 5.7E-23 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 LH59_05015 f18b24bee2dd056fba282ad0364440bf 306 Gene3D G3DSA:3.40.50.720 2 274 1.1E-48 T 14-10-2018 LH59_07555 e236a6403223dd6897250bb4c6461249 151 Gene3D G3DSA:2.40.10.330 76 136 4.5E-35 T 14-10-2018 LH59_07555 e236a6403223dd6897250bb4c6461249 151 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 7 79 3.8E-10 T 14-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain LH59_07555 e236a6403223dd6897250bb4c6461249 151 Gene3D G3DSA:3.10.50.40 25 148 4.5E-35 T 14-10-2018 LH59_07555 e236a6403223dd6897250bb4c6461249 151 SUPERFAMILY SSF54534 5 150 1.22E-29 T 14-10-2018 LH59_26345 54ef9ec22037f6c5fc92be4e02c37c46 239 Gene3D G3DSA:1.10.10.10 1 75 5.8E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_26345 54ef9ec22037f6c5fc92be4e02c37c46 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 61 8.6E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_26345 54ef9ec22037f6c5fc92be4e02c37c46 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 31 45 8.6E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_26345 54ef9ec22037f6c5fc92be4e02c37c46 239 SMART SM00895 95 221 1.1E-21 T 14-10-2018 IPR011711 GntR, C-terminal LH59_26345 54ef9ec22037f6c5fc92be4e02c37c46 239 Gene3D G3DSA:1.20.120.530 82 230 1.2E-28 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_26345 54ef9ec22037f6c5fc92be4e02c37c46 239 Pfam PF07729 FCD domain 96 220 3.6E-22 T 14-10-2018 IPR011711 GntR, C-terminal LH59_26345 54ef9ec22037f6c5fc92be4e02c37c46 239 SMART SM00345 12 71 7.4E-15 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_26345 54ef9ec22037f6c5fc92be4e02c37c46 239 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 71 4.6E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_26345 54ef9ec22037f6c5fc92be4e02c37c46 239 SUPERFAMILY SSF46785 4 75 3.75E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_26345 54ef9ec22037f6c5fc92be4e02c37c46 239 SUPERFAMILY SSF48008 91 226 5.49E-25 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_00520 0c6d0366316ae02f92f68f4ed0a47d5e 323 SUPERFAMILY SSF53850 81 277 3.58E-13 T 14-10-2018 LH59_00520 0c6d0366316ae02f92f68f4ed0a47d5e 323 PIRSF PIRSF017082 1 322 2.4E-86 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_00520 0c6d0366316ae02f92f68f4ed0a47d5e 323 Gene3D G3DSA:3.40.190.150 28 313 2.3E-118 T 14-10-2018 LH59_00520 0c6d0366316ae02f92f68f4ed0a47d5e 323 Gene3D G3DSA:3.40.190.10 125 248 2.3E-118 T 14-10-2018 LH59_00520 0c6d0366316ae02f92f68f4ed0a47d5e 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 318 2.1E-89 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_11980 af7a8887de98b19213422b772a94fbb5 105 SUPERFAMILY SSF46785 5 102 1.87E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_11980 af7a8887de98b19213422b772a94fbb5 105 SMART SM00418 11 103 1.3E-11 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LH59_11980 af7a8887de98b19213422b772a94fbb5 105 Gene3D G3DSA:1.10.10.10 3 105 2.1E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_11980 af7a8887de98b19213422b772a94fbb5 105 Pfam PF12840 Helix-turn-helix domain 10 83 7.2E-16 T 14-10-2018 LH59_21645 0e13c75d4520a3171b667bf53f5faa34 804 Gene3D G3DSA:2.30.30.60 627 675 1.0E-11 T 14-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily LH59_21645 0e13c75d4520a3171b667bf53f5faa34 804 Pfam PF00924 Mechanosensitive ion channel 571 767 1.6E-38 T 14-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 LH59_21645 0e13c75d4520a3171b667bf53f5faa34 804 Pfam PF12607 Protein of unknown function (DUF3772) 135 197 1.6E-18 T 14-10-2018 IPR022249 Domain of unknown function DUF3772 LH59_21645 0e13c75d4520a3171b667bf53f5faa34 804 SUPERFAMILY SSF82689 679 773 1.1E-12 T 14-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 LH59_21645 0e13c75d4520a3171b667bf53f5faa34 804 SUPERFAMILY SSF50182 612 677 3.04E-15 T 14-10-2018 IPR010920 LSM domain superfamily LH59_21645 0e13c75d4520a3171b667bf53f5faa34 804 SUPERFAMILY SSF82861 528 610 4.84E-9 T 14-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 LH59_21645 0e13c75d4520a3171b667bf53f5faa34 804 Gene3D G3DSA:3.30.70.100 684 772 2.4E-8 T 14-10-2018 LH59_07390 12f579936a224bb51d6fb19e023a9efa 213 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 157 191 1.7E-11 T 14-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 LH59_07390 12f579936a224bb51d6fb19e023a9efa 213 Gene3D G3DSA:3.30.1020.10 147 211 1.6E-27 T 14-10-2018 LH59_07390 12f579936a224bb51d6fb19e023a9efa 213 PIRSF PIRSF000239 1 210 1.6E-79 T 14-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 LH59_07390 12f579936a224bb51d6fb19e023a9efa 213 SUPERFAMILY SSF52833 4 210 4.01E-70 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_07390 12f579936a224bb51d6fb19e023a9efa 213 Pfam PF00578 AhpC/TSA family 7 136 7.9E-34 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 LH59_07390 12f579936a224bb51d6fb19e023a9efa 213 Gene3D G3DSA:3.40.30.10 2 146 1.0E-52 T 14-10-2018 LH59_26555 c5dbac560dfa9e74aa025e408fd5fe44 502 Gene3D G3DSA:3.40.50.1100 50 146 3.2E-139 T 14-10-2018 LH59_26555 c5dbac560dfa9e74aa025e408fd5fe44 502 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 20 306 3.8E-82 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme LH59_26555 c5dbac560dfa9e74aa025e408fd5fe44 502 Gene3D G3DSA:3.40.1020.10 328 502 1.5E-74 T 14-10-2018 IPR038110 Threonine dehydratase, ACT-like domain superfamily KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 LH59_26555 c5dbac560dfa9e74aa025e408fd5fe44 502 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 42 55 - T 14-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 LH59_26555 c5dbac560dfa9e74aa025e408fd5fe44 502 SUPERFAMILY SSF55021 409 502 2.11E-28 T 14-10-2018 LH59_26555 c5dbac560dfa9e74aa025e408fd5fe44 502 Gene3D G3DSA:3.40.50.1100 14 317 3.2E-139 T 14-10-2018 LH59_26555 c5dbac560dfa9e74aa025e408fd5fe44 502 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 414 502 2.7E-23 T 14-10-2018 IPR001721 Threonine dehydratase, ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 LH59_26555 c5dbac560dfa9e74aa025e408fd5fe44 502 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 319 408 3.4E-26 T 14-10-2018 IPR001721 Threonine dehydratase, ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 LH59_26555 c5dbac560dfa9e74aa025e408fd5fe44 502 SUPERFAMILY SSF53686 5 355 6.42E-102 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme LH59_26555 c5dbac560dfa9e74aa025e408fd5fe44 502 TIGRFAM TIGR01124 ilvA_2Cterm: threonine ammonia-lyase, biosynthetic 4 502 3.1E-253 T 14-10-2018 IPR005787 Threonine dehydratase, biosynthetic GO:0004794|GO:0009097 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 LH59_07330 9bb089eb44be645ea35b13afc2f8d9b2 303 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 290 5.0E-64 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme LH59_07330 9bb089eb44be645ea35b13afc2f8d9b2 303 Gene3D G3DSA:3.40.50.1100 11 297 1.8E-106 T 14-10-2018 LH59_07330 9bb089eb44be645ea35b13afc2f8d9b2 303 TIGRFAM TIGR01136 cysKM: cysteine synthase 8 301 1.1E-116 T 14-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 LH59_07330 9bb089eb44be645ea35b13afc2f8d9b2 303 SUPERFAMILY SSF53686 4 300 4.58E-89 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme LH59_07330 9bb089eb44be645ea35b13afc2f8d9b2 303 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 38 56 - T 14-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 LH59_07330 9bb089eb44be645ea35b13afc2f8d9b2 303 TIGRFAM TIGR01138 cysM: cysteine synthase B 7 301 5.7E-138 T 14-10-2018 IPR005858 Cysteine synthase CysM GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 LH59_07330 9bb089eb44be645ea35b13afc2f8d9b2 303 Gene3D G3DSA:3.40.50.1100 43 162 1.8E-106 T 14-10-2018 LH59_13325 6f9c299d5127c5433c5dc5d7b4f3aec3 105 TIGRFAM TIGR02174 CXXU_selWTH: selT/selW/selH selenoprotein domain 9 80 1.2E-20 T 14-10-2018 IPR011893 Selenoprotein, Rdx-type LH59_13325 6f9c299d5127c5433c5dc5d7b4f3aec3 105 SUPERFAMILY SSF52833 7 90 8.5E-29 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_13325 6f9c299d5127c5433c5dc5d7b4f3aec3 105 Gene3D G3DSA:3.40.30.10 1 99 1.9E-42 T 14-10-2018 LH59_13325 6f9c299d5127c5433c5dc5d7b4f3aec3 105 Pfam PF10262 Rdx family 8 81 1.2E-34 T 14-10-2018 IPR011893 Selenoprotein, Rdx-type LH59_22395 f6f27404259bdfd56b3272d60d3d5776 205 SUPERFAMILY SSF159709 25 204 5.49E-58 T 14-10-2018 IPR038058 PhnH-like superfamily LH59_22395 f6f27404259bdfd56b3272d60d3d5776 205 Gene3D G3DSA:3.40.50.11310 14 205 4.3E-59 T 14-10-2018 IPR038058 PhnH-like superfamily LH59_22395 f6f27404259bdfd56b3272d60d3d5776 205 PIRSF PIRSF020680 9 205 2.0E-65 T 14-10-2018 IPR008772 Bacterial phosphonate metabolism, PhnH GO:0019634 LH59_22395 f6f27404259bdfd56b3272d60d3d5776 205 TIGRFAM TIGR03292 PhnH_redo: phosphonate C-P lyase system protein PhnH 18 202 7.0E-56 T 14-10-2018 IPR008772 Bacterial phosphonate metabolism, PhnH GO:0019634 LH59_22395 f6f27404259bdfd56b3272d60d3d5776 205 Pfam PF05845 Bacterial phosphonate metabolism protein (PhnH) 17 204 2.6E-63 T 14-10-2018 IPR008772 Bacterial phosphonate metabolism, PhnH GO:0019634 LH59_19465 b53bad5320fc9d81387df5f954fcfd4a 443 ProSitePatterns PS00217 Sugar transport proteins signature 2. 124 149 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 LH59_19465 b53bad5320fc9d81387df5f954fcfd4a 443 Pfam PF07690 Major Facilitator Superfamily 18 351 5.9E-26 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_19465 b53bad5320fc9d81387df5f954fcfd4a 443 Gene3D G3DSA:1.20.1250.20 10 430 6.0E-60 T 14-10-2018 LH59_19465 b53bad5320fc9d81387df5f954fcfd4a 443 SUPERFAMILY SSF103473 1 423 5.89E-64 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_08060 1af435a85fc00376c3a63b7774eb1cba 132 Pfam PF12973 ChrR Cupin-like domain 28 113 8.6E-18 T 14-10-2018 IPR025979 ChrR-like cupin domain LH59_08060 1af435a85fc00376c3a63b7774eb1cba 132 Gene3D G3DSA:2.60.120.10 14 131 1.2E-25 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_08060 1af435a85fc00376c3a63b7774eb1cba 132 SUPERFAMILY SSF51182 20 117 1.86E-27 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_02520 3fa95a6b43fa94faea9accf992925de5 226 Gene3D G3DSA:3.40.50.150 3 224 9.4E-50 T 14-10-2018 LH59_02520 3fa95a6b43fa94faea9accf992925de5 226 SUPERFAMILY SSF53335 8 189 1.69E-39 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_02520 3fa95a6b43fa94faea9accf992925de5 226 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 17 211 5.2E-36 T 14-10-2018 LH59_09435 72fd748c262dec4a5cd48b8b46e9d5a5 376 Gene3D G3DSA:3.40.50.720 1 140 4.6E-57 T 14-10-2018 LH59_09435 72fd748c262dec4a5cd48b8b46e9d5a5 376 SMART SM00859 4 123 1.4E-25 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 LH59_09435 72fd748c262dec4a5cd48b8b46e9d5a5 376 PIRSF PIRSF000148 3 376 2.9E-59 T 14-10-2018 LH59_09435 72fd748c262dec4a5cd48b8b46e9d5a5 376 SUPERFAMILY SSF55347 135 360 1.13E-70 T 14-10-2018 LH59_09435 72fd748c262dec4a5cd48b8b46e9d5a5 376 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 267 281 - T 14-10-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 LH59_09435 72fd748c262dec4a5cd48b8b46e9d5a5 376 SUPERFAMILY SSF51735 4 148 3.33E-49 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_09435 72fd748c262dec4a5cd48b8b46e9d5a5 376 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 2 373 33.08 T 14-10-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 LH59_09435 72fd748c262dec4a5cd48b8b46e9d5a5 376 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 5 122 1.0E-21 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 LH59_09435 72fd748c262dec4a5cd48b8b46e9d5a5 376 TIGRFAM TIGR01745 asd_gamma: aspartate-semialdehyde dehydrogenase 4 371 5.4E-182 T 14-10-2018 IPR011534 Aspartate-semialdehyde dehydrogenase, gamma-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 LH59_09435 72fd748c262dec4a5cd48b8b46e9d5a5 376 Gene3D G3DSA:3.30.360.10 141 356 7.4E-79 T 14-10-2018 LH59_09435 72fd748c262dec4a5cd48b8b46e9d5a5 376 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 145 359 1.7E-53 T 14-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 LH59_06440 ccd9488e032717cdacbee1afd615a2ac 1024 Pfam PF00575 S1 RNA binding domain 36 117 3.3E-11 T 14-10-2018 IPR003029 S1 domain GO:0003676 LH59_06440 ccd9488e032717cdacbee1afd615a2ac 1024 SUPERFAMILY SSF50249 39 124 4.24E-18 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_06440 ccd9488e032717cdacbee1afd615a2ac 1024 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 423 3.2E-157 T 14-10-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 LH59_06440 ccd9488e032717cdacbee1afd615a2ac 1024 SMART SM00316 37 118 7.1E-10 T 14-10-2018 IPR022967 RNA-binding domain, S1 LH59_06440 ccd9488e032717cdacbee1afd615a2ac 1024 Hamap MF_00970 Ribonuclease E [rne]. 1 1012 36.187 T 14-10-2018 IPR028878 Ribonuclease E GO:0006396|GO:0008995 LH59_06440 ccd9488e032717cdacbee1afd615a2ac 1024 Gene3D G3DSA:3.40.1260.20 399 506 2.7E-38 T 14-10-2018 LH59_06440 ccd9488e032717cdacbee1afd615a2ac 1024 Pfam PF10150 Ribonuclease E/G family 120 389 5.2E-91 T 14-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 LH59_06440 ccd9488e032717cdacbee1afd615a2ac 1024 Gene3D G3DSA:2.40.50.140 31 124 9.4E-31 T 14-10-2018 LH59_23180 8f04c4599452e29bfd8a63af6b5889d7 277 Pfam PF01497 Periplasmic binding protein 25 249 4.9E-40 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain LH59_23180 8f04c4599452e29bfd8a63af6b5889d7 277 SUPERFAMILY SSF53807 20 267 4.32E-49 T 14-10-2018 LH59_23180 8f04c4599452e29bfd8a63af6b5889d7 277 Gene3D G3DSA:3.40.50.1980 141 276 1.3E-37 T 14-10-2018 LH59_23180 8f04c4599452e29bfd8a63af6b5889d7 277 Gene3D G3DSA:3.40.50.1980 19 140 6.2E-42 T 14-10-2018 LH59_09295 aef3bd4100c8870567ad8d7e9634de0b 552 Gene3D G3DSA:2.60.200.20 3 100 4.2E-14 T 14-10-2018 LH59_09295 aef3bd4100c8870567ad8d7e9634de0b 552 SUPERFAMILY SSF52540 183 481 5.47E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_09295 aef3bd4100c8870567ad8d7e9634de0b 552 Gene3D G3DSA:3.40.50.300 299 512 3.7E-68 T 14-10-2018 LH59_09295 aef3bd4100c8870567ad8d7e9634de0b 552 SMART SM00240 21 71 2.1E-4 T 14-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 LH59_09295 aef3bd4100c8870567ad8d7e9634de0b 552 Pfam PF00437 Type II/IV secretion system protein 199 476 5.7E-82 T 14-10-2018 IPR001482 Type II/IV secretion system protein LH59_09295 aef3bd4100c8870567ad8d7e9634de0b 552 Pfam PF00498 FHA domain 24 86 1.9E-8 T 14-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 LH59_09295 aef3bd4100c8870567ad8d7e9634de0b 552 Gene3D G3DSA:3.30.450.380 129 293 1.7E-35 T 14-10-2018 LH59_09295 aef3bd4100c8870567ad8d7e9634de0b 552 SUPERFAMILY SSF49879 19 95 1.05E-15 T 14-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 LH59_27655 bd1df07933df8d8a22c46b8ab363ccf0 213 SUPERFAMILY SSF52540 44 203 2.92E-29 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_27655 bd1df07933df8d8a22c46b8ab363ccf0 213 Pfam PF01202 Shikimate kinase 50 206 2.7E-48 T 14-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 LH59_27655 bd1df07933df8d8a22c46b8ab363ccf0 213 ProSitePatterns PS01128 Shikimate kinase signature. 97 122 - T 14-10-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 LH59_27655 bd1df07933df8d8a22c46b8ab363ccf0 213 Hamap MF_00109 Shikimate kinase [aroK]. 41 207 28.832 T 14-10-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 LH59_27655 bd1df07933df8d8a22c46b8ab363ccf0 213 PRINTS PR01100 Shikimate kinase family signature 44 59 4.7E-24 T 14-10-2018 LH59_27655 bd1df07933df8d8a22c46b8ab363ccf0 213 PRINTS PR01100 Shikimate kinase family signature 135 152 4.7E-24 T 14-10-2018 LH59_27655 bd1df07933df8d8a22c46b8ab363ccf0 213 PRINTS PR01100 Shikimate kinase family signature 114 123 4.7E-24 T 14-10-2018 LH59_27655 bd1df07933df8d8a22c46b8ab363ccf0 213 PRINTS PR01100 Shikimate kinase family signature 68 81 4.7E-24 T 14-10-2018 LH59_27655 bd1df07933df8d8a22c46b8ab363ccf0 213 PRINTS PR01100 Shikimate kinase family signature 96 104 4.7E-24 T 14-10-2018 LH59_27655 bd1df07933df8d8a22c46b8ab363ccf0 213 Gene3D G3DSA:3.40.50.300 43 212 3.2E-52 T 14-10-2018 LH59_15785 c55e0944ffff03f961e08f225764f3db 222 Gene3D G3DSA:2.40.50.180 93 209 3.1E-14 T 14-10-2018 LH59_15785 c55e0944ffff03f961e08f225764f3db 222 Gene3D G3DSA:2.30.30.40 76 208 3.1E-14 T 14-10-2018 LH59_15785 c55e0944ffff03f961e08f225764f3db 222 SUPERFAMILY SSF50341 74 218 9.16E-23 T 14-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 LH59_15785 c55e0944ffff03f961e08f225764f3db 222 Pfam PF01584 CheW-like domain 75 216 3.4E-18 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 LH59_15785 c55e0944ffff03f961e08f225764f3db 222 SMART SM00260 70 214 5.1E-7 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 LH59_08715 4ee2ee3a785e81e0166cc279636cf8dd 431 Pfam PF09821 C-terminal AAA-associated domain 299 417 3.2E-38 T 14-10-2018 IPR018632 C-terminal AAA-associated domain LH59_08715 4ee2ee3a785e81e0166cc279636cf8dd 431 SUPERFAMILY SSF52540 6 241 6.65E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_08715 4ee2ee3a785e81e0166cc279636cf8dd 431 SMART SM00382 36 220 1.4E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_08715 4ee2ee3a785e81e0166cc279636cf8dd 431 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_08715 4ee2ee3a785e81e0166cc279636cf8dd 431 Gene3D G3DSA:3.40.50.300 4 293 2.4E-63 T 14-10-2018 LH59_08715 4ee2ee3a785e81e0166cc279636cf8dd 431 Pfam PF00005 ABC transporter 27 166 6.6E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_08195 15e89ae10899086699a4b4315dcc9531 372 SUPERFAMILY SSF51735 136 320 2.1E-38 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_08195 15e89ae10899086699a4b4315dcc9531 372 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 140 370 1.4E-72 T 14-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain LH59_08195 15e89ae10899086699a4b4315dcc9531 372 SUPERFAMILY SSF52283 1 167 8.5E-47 T 14-10-2018 LH59_08195 15e89ae10899086699a4b4315dcc9531 372 Gene3D G3DSA:3.40.50.720 3 366 2.1E-139 T 14-10-2018 LH59_08195 15e89ae10899086699a4b4315dcc9531 372 SMART SM01002 145 314 2.5E-82 T 14-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain LH59_08195 15e89ae10899086699a4b4315dcc9531 372 SMART SM01003 4 136 5.7E-62 T 14-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal LH59_08195 15e89ae10899086699a4b4315dcc9531 372 Gene3D G3DSA:3.40.50.720 136 321 2.1E-139 T 14-10-2018 LH59_08195 15e89ae10899086699a4b4315dcc9531 372 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 136 2.8E-38 T 14-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal LH59_19410 d4b50b9f63f9a8ec4e708ef8b60d18a7 705 SUPERFAMILY SSF51445 135 697 8.17E-124 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily LH59_19410 d4b50b9f63f9a8ec4e708ef8b60d18a7 705 Pfam PF02446 4-alpha-glucanotransferase 160 678 5.3E-100 T 14-10-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 LH59_19410 d4b50b9f63f9a8ec4e708ef8b60d18a7 705 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 119 676 1.2E-88 T 14-10-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 LH59_19410 d4b50b9f63f9a8ec4e708ef8b60d18a7 705 Gene3D G3DSA:3.20.20.80 150 687 3.5E-117 T 14-10-2018 LH59_07645 2d38a274d98ff73dc0f79cae8251655f 249 SUPERFAMILY SSF55120 9 226 8.15E-80 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 LH59_07645 2d38a274d98ff73dc0f79cae8251655f 249 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 181 222 6.8E-15 T 14-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 LH59_07645 2d38a274d98ff73dc0f79cae8251655f 249 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 31 180 3.7E-57 T 14-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 LH59_07645 2d38a274d98ff73dc0f79cae8251655f 249 Gene3D G3DSA:3.30.2350.10 1 239 2.6E-90 T 14-10-2018 LH59_07645 2d38a274d98ff73dc0f79cae8251655f 249 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 10 219 2.1E-77 T 14-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 LH59_07645 2d38a274d98ff73dc0f79cae8251655f 249 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 9 245 18.532 T 14-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 LH59_06145 e71523aba25acc9cc1815e46bff980ed 162 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 19 140 7.3E-46 T 14-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06145 e71523aba25acc9cc1815e46bff980ed 162 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 10 159 27.503 T 14-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06145 e71523aba25acc9cc1815e46bff980ed 162 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 102 113 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site LH59_06145 e71523aba25acc9cc1815e46bff980ed 162 Pfam PF12838 4Fe-4S dicluster domain 62 115 5.1E-12 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain LH59_06145 e71523aba25acc9cc1815e46bff980ed 162 SUPERFAMILY SSF54862 36 145 6.7E-24 T 14-10-2018 LH59_06145 e71523aba25acc9cc1815e46bff980ed 162 Gene3D G3DSA:3.30.70.3270 36 161 7.9E-37 T 14-10-2018 LH59_02850 44208ff5ae21b01fd55384617391910c 373 Gene3D G3DSA:3.40.50.300 4 221 6.0E-64 T 14-10-2018 LH59_02850 44208ff5ae21b01fd55384617391910c 373 SUPERFAMILY SSF52540 4 242 7.35E-84 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_02850 44208ff5ae21b01fd55384617391910c 373 Pfam PF08402 TOBE domain 283 358 3.4E-7 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 LH59_02850 44208ff5ae21b01fd55384617391910c 373 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_02850 44208ff5ae21b01fd55384617391910c 373 Pfam PF00005 ABC transporter 21 161 2.4E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_02850 44208ff5ae21b01fd55384617391910c 373 SUPERFAMILY SSF50331 237 364 8.5E-22 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal LH59_02850 44208ff5ae21b01fd55384617391910c 373 SMART SM00382 28 219 5.7E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_02850 44208ff5ae21b01fd55384617391910c 373 Gene3D G3DSA:2.40.50.940 222 359 2.9E-26 T 14-10-2018 LH59_02850 44208ff5ae21b01fd55384617391910c 373 Gene3D G3DSA:2.40.50.140 290 350 2.9E-26 T 14-10-2018 LH59_16770 2df95fff33cb9e500e67bc3f7020ef44 303 Gene3D G3DSA:1.20.1250.20 71 287 9.1E-25 T 14-10-2018 LH59_16770 2df95fff33cb9e500e67bc3f7020ef44 303 SUPERFAMILY SSF103473 4 278 3.79E-33 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_16770 2df95fff33cb9e500e67bc3f7020ef44 303 Pfam PF07690 Major Facilitator Superfamily 9 188 2.9E-16 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_00125 999887fe35af7c9cbd164c1693bb1ad2 109 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 14 90 7.3E-22 T 14-10-2018 LH59_00125 999887fe35af7c9cbd164c1693bb1ad2 109 Gene3D G3DSA:3.10.20.440 3 97 3.0E-8 T 14-10-2018 LH59_00125 999887fe35af7c9cbd164c1693bb1ad2 109 SUPERFAMILY SSF54292 15 91 1.19E-17 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 LH59_26255 8dcdd3700435b439422a699167296b0a 323 Gene3D G3DSA:3.40.50.1820 47 321 4.0E-71 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_26255 8dcdd3700435b439422a699167296b0a 323 SUPERFAMILY SSF53474 50 319 9.19E-51 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_26255 8dcdd3700435b439422a699167296b0a 323 Pfam PF00756 Putative esterase 70 256 1.3E-13 T 14-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 LH59_23050 63e59971a973285d32b501ba83c04768 154 SUPERFAMILY SSF55729 5 135 3.09E-25 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_23050 63e59971a973285d32b501ba83c04768 154 Pfam PF13673 Acetyltransferase (GNAT) domain 61 139 7.1E-11 T 14-10-2018 IPR000182 GNAT domain LH59_23050 63e59971a973285d32b501ba83c04768 154 Gene3D G3DSA:3.40.630.30 2 140 1.7E-23 T 14-10-2018 LH59_00380 e11a08324913fe1575c19c1becae0b70 218 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 36 212 4.7E-12 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_00380 e11a08324913fe1575c19c1becae0b70 218 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 11 107 3.3E-27 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 LH59_00380 e11a08324913fe1575c19c1becae0b70 218 SUPERFAMILY SSF161098 13 207 5.36E-37 T 14-10-2018 IPR035906 MetI-like superfamily LH59_00380 e11a08324913fe1575c19c1becae0b70 218 Gene3D G3DSA:1.10.3720.10 5 214 1.2E-43 T 14-10-2018 IPR035906 MetI-like superfamily LH59_12555 8d31916e8cb2378febaf73f0b7521a17 356 Gene3D G3DSA:2.40.160.10 24 356 1.8E-69 T 14-10-2018 IPR023614 Porin domain superfamily LH59_12555 8d31916e8cb2378febaf73f0b7521a17 356 Pfam PF13609 Gram-negative porin 9 333 1.4E-42 T 14-10-2018 LH59_12555 8d31916e8cb2378febaf73f0b7521a17 356 SUPERFAMILY SSF56935 23 356 3.33E-69 T 14-10-2018 LH59_21185 29cfe074d641fe49be896b977f545003 190 Pfam PF01066 CDP-alcohol phosphatidyltransferase 4 76 1.6E-16 T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 LH59_21185 29cfe074d641fe49be896b977f545003 190 PIRSF PIRSF000847 1 190 7.4E-44 T 14-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 LH59_21185 29cfe074d641fe49be896b977f545003 190 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 4 186 1.3E-50 T 14-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 LH59_21185 29cfe074d641fe49be896b977f545003 190 Gene3D G3DSA:1.20.120.1760 4 190 1.7E-11 T 14-10-2018 LH59_21185 29cfe074d641fe49be896b977f545003 190 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 54 76 - T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 LH59_21725 ee6a6d352a9b6aab9c226738626a3c94 146 SUPERFAMILY SSF54631 11 142 1.26E-32 T 14-10-2018 LH59_21725 ee6a6d352a9b6aab9c226738626a3c94 146 Gene3D G3DSA:3.10.580.10 1 132 3.2E-45 T 14-10-2018 LH59_21725 ee6a6d352a9b6aab9c226738626a3c94 146 SMART SM00116 15 62 2.8E-6 T 14-10-2018 IPR000644 CBS domain LH59_21725 ee6a6d352a9b6aab9c226738626a3c94 146 SMART SM00116 80 127 1.8E-8 T 14-10-2018 IPR000644 CBS domain LH59_21725 ee6a6d352a9b6aab9c226738626a3c94 146 Pfam PF00571 CBS domain 73 124 3.3E-11 T 14-10-2018 IPR000644 CBS domain LH59_21725 ee6a6d352a9b6aab9c226738626a3c94 146 Pfam PF00571 CBS domain 13 62 9.8E-10 T 14-10-2018 IPR000644 CBS domain LH59_16780 b87f37c7a791a112007185eb14ef8770 117 Pfam PF02656 Domain of unknown function (DUF202) 18 78 3.1E-13 T 14-10-2018 IPR003807 Domain of unknown function DUF202 LH59_27370 463467ccc86f378d09e4745f26ffb767 434 Gene3D G3DSA:3.40.50.2000 123 428 6.2E-11 T 14-10-2018 LH59_27370 463467ccc86f378d09e4745f26ffb767 434 Gene3D G3DSA:3.40.50.2000 220 411 6.2E-11 T 14-10-2018 LH59_27370 463467ccc86f378d09e4745f26ffb767 434 SUPERFAMILY SSF53756 65 429 4.81E-21 T 14-10-2018 LH59_19965 79a68e864eb4bbd6fb0945fff6435275 476 Pfam PF01050 Mannose-6-phosphate isomerase 321 471 1.1E-70 T 14-10-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 LH59_19965 79a68e864eb4bbd6fb0945fff6435275 476 SUPERFAMILY SSF53448 8 285 6.34E-67 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases LH59_19965 79a68e864eb4bbd6fb0945fff6435275 476 Gene3D G3DSA:3.90.550.10 8 353 2.0E-112 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases LH59_19965 79a68e864eb4bbd6fb0945fff6435275 476 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 10 475 2.4E-199 T 14-10-2018 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 LH59_19965 79a68e864eb4bbd6fb0945fff6435275 476 Pfam PF00483 Nucleotidyl transferase 10 293 2.5E-57 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 LH59_19965 79a68e864eb4bbd6fb0945fff6435275 476 Gene3D G3DSA:2.60.120.10 354 463 1.5E-18 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_19965 79a68e864eb4bbd6fb0945fff6435275 476 SUPERFAMILY SSF51182 191 475 2.28E-79 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_25710 13300ec91de927299cf8421ab7adb498 284 Gene3D G3DSA:3.30.450.180 107 281 5.8E-12 T 14-10-2018 LH59_25710 13300ec91de927299cf8421ab7adb498 284 Pfam PF13560 Helix-turn-helix domain 7 84 4.5E-16 T 14-10-2018 LH59_25710 13300ec91de927299cf8421ab7adb498 284 SUPERFAMILY SSF47413 31 81 1.13E-5 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 LH59_25710 13300ec91de927299cf8421ab7adb498 284 SMART SM00530 11 83 1.1E-6 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LH59_10685 7fa25fd7768850eacb92148ca8fa92f1 199 Gene3D G3DSA:3.40.30.10 3 199 1.0E-54 T 14-10-2018 LH59_10685 7fa25fd7768850eacb92148ca8fa92f1 199 Pfam PF01323 DSBA-like thioredoxin domain 3 195 1.4E-34 T 14-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 LH59_10685 7fa25fd7768850eacb92148ca8fa92f1 199 SUPERFAMILY SSF52833 3 197 9.23E-38 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_10685 7fa25fd7768850eacb92148ca8fa92f1 199 PIRSF PIRSF006386 1 199 1.3E-52 T 14-10-2018 IPR014440 HCCA isomerase/glutathione S-transferase kappa Reactome: R-HSA-156590|Reactome: R-HSA-9033241 LH59_28175 daff4e7ebf2fc1b953df3359ce19861c 151 Gene3D G3DSA:3.40.630.30 2 149 3.6E-27 T 14-10-2018 LH59_28175 daff4e7ebf2fc1b953df3359ce19861c 151 SUPERFAMILY SSF55729 1 149 9.09E-30 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_28175 daff4e7ebf2fc1b953df3359ce19861c 151 Pfam PF00583 Acetyltransferase (GNAT) family 69 129 5.1E-12 T 14-10-2018 IPR000182 GNAT domain LH59_06250 0ad89c6878fbdd0380aac7fdecc4c44e 354 Gene3D G3DSA:3.30.1400.10 220 334 3.5E-5 T 14-10-2018 IPR036765 ZipA, C-terminal FtsZ-binding domain superfamily GO:0090529 LH59_06250 0ad89c6878fbdd0380aac7fdecc4c44e 354 SMART SM00771 210 332 4.8E-27 T 14-10-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 LH59_06250 0ad89c6878fbdd0380aac7fdecc4c44e 354 Pfam PF04354 ZipA, C-terminal FtsZ-binding domain 276 322 4.2E-7 T 14-10-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 LH59_06250 0ad89c6878fbdd0380aac7fdecc4c44e 354 SUPERFAMILY SSF64383 223 335 7.59E-12 T 14-10-2018 IPR036765 ZipA, C-terminal FtsZ-binding domain superfamily GO:0090529 LH59_26125 b02ec771728eff0f366af29f9997c5ce 108 Gene3D G3DSA:3.40.30.10 7 104 4.4E-34 T 14-10-2018 LH59_26125 b02ec771728eff0f366af29f9997c5ce 108 SUPERFAMILY SSF52833 1 106 6.72E-34 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_26125 b02ec771728eff0f366af29f9997c5ce 108 TIGRFAM TIGR00365 TIGR00365: monothiol glutaredoxin, Grx4 family 5 102 3.7E-45 T 14-10-2018 IPR004480 Monothiol glutaredoxin-related LH59_26125 b02ec771728eff0f366af29f9997c5ce 108 PIRSF PIRSF005894 1 108 4.8E-48 T 14-10-2018 IPR014434 Monothiol glutaredoxin GO:0015036 Reactome: R-HSA-1362409 LH59_26125 b02ec771728eff0f366af29f9997c5ce 108 Pfam PF00462 Glutaredoxin 17 82 1.6E-18 T 14-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 LH59_23130 f4c65c64916d838d723879e490b655fd 142 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 4 116 8.3E-45 T 14-10-2018 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 LH59_23130 f4c65c64916d838d723879e490b655fd 142 SUPERFAMILY SSF52833 3 138 2.04E-39 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_23130 f4c65c64916d838d723879e490b655fd 142 Pfam PF03960 ArsC family 7 114 1.4E-14 T 14-10-2018 IPR006660 Arsenate reductase-like LH59_23130 f4c65c64916d838d723879e490b655fd 142 Gene3D G3DSA:3.40.30.10 1 141 1.3E-58 T 14-10-2018 LH59_08475 546a6e10c11dbedf4f5b52b26d9cb7c0 203 SMART SM01144 2 187 2.2E-60 T 14-10-2018 IPR005636 DTW LH59_08475 546a6e10c11dbedf4f5b52b26d9cb7c0 203 Pfam PF03942 DTW domain 3 181 2.8E-42 T 14-10-2018 IPR005636 DTW LH59_19570 084f63e18937117f1da54dd3c60e6559 219 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 31 215 1.4E-19 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_19570 084f63e18937117f1da54dd3c60e6559 219 Gene3D G3DSA:1.10.3720.10 7 217 1.8E-47 T 14-10-2018 IPR035906 MetI-like superfamily LH59_19570 084f63e18937117f1da54dd3c60e6559 219 SUPERFAMILY SSF161098 13 200 7.72E-41 T 14-10-2018 IPR035906 MetI-like superfamily LH59_19570 084f63e18937117f1da54dd3c60e6559 219 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 108 2.3E-23 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 LH59_05135 e6686daca20f0800f8cc3c3c6722b8c9 684 Gene3D G3DSA:2.40.170.20 28 684 9.3E-180 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_05135 e6686daca20f0800f8cc3c3c6722b8c9 684 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 38 682 1.3E-73 T 14-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 LH59_05135 e6686daca20f0800f8cc3c3c6722b8c9 684 Pfam PF07715 TonB-dependent Receptor Plug Domain 37 141 4.0E-15 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_05135 e6686daca20f0800f8cc3c3c6722b8c9 684 Pfam PF00593 TonB dependent receptor 263 682 1.1E-46 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_05135 e6686daca20f0800f8cc3c3c6722b8c9 684 SUPERFAMILY SSF56935 12 683 1.1E-103 T 14-10-2018 LH59_05455 4494c87c4e180a4f91893244679e546a 109 SUPERFAMILY SSF103481 5 104 4.32E-21 T 14-10-2018 LH59_05455 4494c87c4e180a4f91893244679e546a 109 Gene3D G3DSA:1.10.3730.20 1 109 6.7E-41 T 14-10-2018 LH59_05455 4494c87c4e180a4f91893244679e546a 109 Pfam PF00893 Small Multidrug Resistance protein 1 93 2.4E-32 T 14-10-2018 IPR000390 Small multidrug resistance protein family GO:0016021 LH59_21540 4ad90c0ee507138d12aabe4b8bf71553 179 Pfam PF00583 Acetyltransferase (GNAT) family 40 139 3.2E-16 T 14-10-2018 IPR000182 GNAT domain LH59_21540 4ad90c0ee507138d12aabe4b8bf71553 179 SUPERFAMILY SSF55729 1 170 5.14E-35 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_21540 4ad90c0ee507138d12aabe4b8bf71553 179 Gene3D G3DSA:3.40.630.30 1 173 1.2E-49 T 14-10-2018 LH59_10990 664deb7607c55622aac2ae2e6b1f2e8a 410 Pfam PF12573 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal 6 44 1.3E-18 T 14-10-2018 IPR022593 2-oxoisovalerate dehydrogenase, E1 alpha subunit, N-terminal domain KEGG: 00280+1.2.4.4|KEGG: 00640+1.2.4.4|MetaCyc: PWY-5046 LH59_10990 664deb7607c55622aac2ae2e6b1f2e8a 410 Pfam PF00676 Dehydrogenase E1 component 81 377 6.2E-101 T 14-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 LH59_10990 664deb7607c55622aac2ae2e6b1f2e8a 410 Gene3D G3DSA:3.40.50.970 2 408 1.3E-122 T 14-10-2018 LH59_10990 664deb7607c55622aac2ae2e6b1f2e8a 410 SUPERFAMILY SSF52518 46 407 2.59E-94 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold LH59_21230 ff1001d810a4282acb6fcfeac57d7400 398 Pfam PF12536 Patatin phospholipase 277 381 2.7E-35 T 14-10-2018 IPR021095 Protein of unknown function DUF3734 LH59_21230 ff1001d810a4282acb6fcfeac57d7400 398 Pfam PF01734 Patatin-like phospholipase 23 82 7.7E-13 T 14-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 LH59_21230 ff1001d810a4282acb6fcfeac57d7400 398 Pfam PF01734 Patatin-like phospholipase 153 240 8.2E-9 T 14-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 LH59_21230 ff1001d810a4282acb6fcfeac57d7400 398 SUPERFAMILY SSF52151 20 371 2.96E-53 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase LH59_21230 ff1001d810a4282acb6fcfeac57d7400 398 Gene3D G3DSA:3.40.1090.10 5 104 1.0E-16 T 14-10-2018 LH59_21230 ff1001d810a4282acb6fcfeac57d7400 398 Gene3D G3DSA:3.40.1090.10 146 296 2.2E-13 T 14-10-2018 LH59_19905 d1b03f57d3a1339377be51431286686c 420 Gene3D G3DSA:3.90.1150.10 9 414 5.8E-154 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_19905 d1b03f57d3a1339377be51431286686c 420 Pfam PF00202 Aminotransferase class-III 24 416 5.7E-123 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LH59_19905 d1b03f57d3a1339377be51431286686c 420 SUPERFAMILY SSF53383 23 418 2.26E-130 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_19905 d1b03f57d3a1339377be51431286686c 420 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 9 419 5.6E-183 T 14-10-2018 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 LH59_19905 d1b03f57d3a1339377be51431286686c 420 PIRSF PIRSF000521 121 420 2.0E-44 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LH59_19905 d1b03f57d3a1339377be51431286686c 420 PIRSF PIRSF000521 3 127 4.2E-4 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LH59_19905 d1b03f57d3a1339377be51431286686c 420 Gene3D G3DSA:3.40.640.10 58 317 5.8E-154 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_19905 d1b03f57d3a1339377be51431286686c 420 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 235 272 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LH59_13750 21f3de3d4e38a8d78742f4203f1721f0 441 Gene3D G3DSA:1.20.1250.20 11 431 8.6E-50 T 14-10-2018 LH59_13750 21f3de3d4e38a8d78742f4203f1721f0 441 Pfam PF00083 Sugar (and other) transporter 16 228 8.7E-21 T 14-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 LH59_13750 21f3de3d4e38a8d78742f4203f1721f0 441 SUPERFAMILY SSF103473 13 430 6.93E-54 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_11615 75bf61613beb1bb8ceebfc77f97d6f11 506 SUPERFAMILY SSF53271 252 483 1.19E-72 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like LH59_11615 75bf61613beb1bb8ceebfc77f97d6f11 506 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 2 466 2.6E-157 T 14-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 LH59_11615 75bf61613beb1bb8ceebfc77f97d6f11 506 Pfam PF00156 Phosphoribosyl transferase domain 285 395 4.6E-8 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 LH59_11615 75bf61613beb1bb8ceebfc77f97d6f11 506 Pfam PF13522 Glutamine amidotransferase domain 64 210 3.8E-16 T 14-10-2018 LH59_11615 75bf61613beb1bb8ceebfc77f97d6f11 506 PIRSF PIRSF000485 1 482 2.6E-155 T 14-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 LH59_11615 75bf61613beb1bb8ceebfc77f97d6f11 506 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 1 466 45.311 T 14-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 LH59_11615 75bf61613beb1bb8ceebfc77f97d6f11 506 SUPERFAMILY SSF56235 2 259 1.63E-68 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal LH59_11615 75bf61613beb1bb8ceebfc77f97d6f11 506 Gene3D G3DSA:3.40.50.2020 279 443 1.3E-147 T 14-10-2018 LH59_11615 75bf61613beb1bb8ceebfc77f97d6f11 506 Gene3D G3DSA:3.60.20.10 2 414 1.3E-147 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal LH59_13380 88d865b3c7a6a58d1c6fe296847c5b01 394 SUPERFAMILY SSF53850 17 369 2.71E-44 T 14-10-2018 LH59_13380 88d865b3c7a6a58d1c6fe296847c5b01 394 Pfam PF12849 PBP superfamily domain 12 340 3.6E-35 T 14-10-2018 IPR024370 PBP domain LH59_13380 88d865b3c7a6a58d1c6fe296847c5b01 394 Gene3D G3DSA:3.40.190.10 115 261 1.6E-104 T 14-10-2018 LH59_13380 88d865b3c7a6a58d1c6fe296847c5b01 394 Gene3D G3DSA:3.40.190.260 18 393 1.6E-104 T 14-10-2018 LH59_14510 211d98bb340d247c74143cb15f794b8f 165 Gene3D G3DSA:2.20.25.120 48 80 1.6E-55 T 14-10-2018 LH59_14510 211d98bb340d247c74143cb15f794b8f 165 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 4 136 3.7E-49 T 14-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 LH59_14510 211d98bb340d247c74143cb15f794b8f 165 Gene3D G3DSA:3.40.50.300 6 158 1.6E-55 T 14-10-2018 LH59_14510 211d98bb340d247c74143cb15f794b8f 165 SUPERFAMILY SSF52540 3 162 1.93E-26 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_14510 211d98bb340d247c74143cb15f794b8f 165 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 4 160 6.5E-47 T 14-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 LH59_12085 ebb0cb8ee896b67a56ac034af7a1f80e 296 SUPERFAMILY SSF161098 50 275 9.94E-46 T 14-10-2018 IPR035906 MetI-like superfamily LH59_12085 ebb0cb8ee896b67a56ac034af7a1f80e 296 Gene3D G3DSA:1.10.3720.10 45 286 7.9E-51 T 14-10-2018 IPR035906 MetI-like superfamily LH59_12085 ebb0cb8ee896b67a56ac034af7a1f80e 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 280 7.8E-18 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_25910 4901c170ea7b6961095486b327822d21 237 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 6 237 50.311 T 14-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 LH59_25910 4901c170ea7b6961095486b327822d21 237 SUPERFAMILY SSF52402 7 231 1.06E-52 T 14-10-2018 LH59_25910 4901c170ea7b6961095486b327822d21 237 Pfam PF06508 Queuosine biosynthesis protein QueC 7 231 4.4E-68 T 14-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 LH59_25910 4901c170ea7b6961095486b327822d21 237 Gene3D G3DSA:3.40.50.620 4 235 1.4E-62 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LH59_25910 4901c170ea7b6961095486b327822d21 237 PIRSF PIRSF006293 4 235 1.0E-64 T 14-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 LH59_25910 4901c170ea7b6961095486b327822d21 237 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 8 224 1.9E-56 T 14-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 LH59_03885 1f45ac71c997bff7ce5a114674f30667 154 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 10 145 2.3E-23 T 14-10-2018 IPR009936 Protein of unknown function DUF1468 LH59_08880 a220098f31215c0e38f80a2a4250fb18 507 SUPERFAMILY SSF52540 15 379 1.53E-53 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_08880 a220098f31215c0e38f80a2a4250fb18 507 Gene3D G3DSA:3.40.50.300 4 82 8.4E-9 T 14-10-2018 LH59_08880 a220098f31215c0e38f80a2a4250fb18 507 Pfam PF05872 Bacterial protein of unknown function (DUF853) 5 504 1.0E-233 T 14-10-2018 IPR033186 Helicase HerA-like C-terminal LH59_08880 a220098f31215c0e38f80a2a4250fb18 507 Gene3D G3DSA:3.40.50.300 202 376 4.4E-20 T 14-10-2018 LH59_08280 bc21afb965981ec726a9253532078e6b 253 SUPERFAMILY SSF51306 149 249 3.92E-17 T 14-10-2018 IPR036286 LexA/Signal peptidase-like superfamily LH59_08280 bc21afb965981ec726a9253532078e6b 253 Pfam PF00717 Peptidase S24-like 166 233 2.2E-8 T 14-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C LH59_08280 bc21afb965981ec726a9253532078e6b 253 Gene3D G3DSA:2.10.109.10 145 251 1.7E-8 T 14-10-2018 LH59_12930 69673b59b81e795083ed6e8f67db7b8e 184 Hamap MF_02088 Probable queuosine precursor transporter. 14 183 14.349 T 14-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 LH59_12930 69673b59b81e795083ed6e8f67db7b8e 184 TIGRFAM TIGR00697 TIGR00697: conserved hypothetical integral membrane protein 84 166 1.5E-15 T 14-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 LH59_12930 69673b59b81e795083ed6e8f67db7b8e 184 Pfam PF02592 Putative vitamin uptake transporter 43 84 1.3E-9 T 14-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 LH59_12930 69673b59b81e795083ed6e8f67db7b8e 184 Pfam PF02592 Putative vitamin uptake transporter 86 172 2.8E-20 T 14-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 LH59_04130 e6763b65c5fefef2da5cde214be6be7a 203 Pfam PF04752 ChaC-like protein 33 196 3.6E-43 T 14-10-2018 IPR006840 Glutathione-specific gamma-glutamylcyclotransferase GO:0003839|GO:0006751 KEGG: 00480+4.3.2.7|MetaCyc: PWY-7942|Reactome: R-HSA-174403 LH59_04130 e6763b65c5fefef2da5cde214be6be7a 203 SUPERFAMILY SSF110857 33 145 3.92E-12 T 14-10-2018 IPR036568 Gamma-glutamyl cyclotransferase-like superfamily LH59_04130 e6763b65c5fefef2da5cde214be6be7a 203 Gene3D G3DSA:3.10.490.10 27 198 2.4E-10 T 14-10-2018 LH59_19415 a1d83712ad8571081108a15d15d6393e 886 SMART SM00642 6 492 1.8E-7 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 LH59_19415 a1d83712ad8571081108a15d15d6393e 886 TIGRFAM TIGR02401 trehalose_TreY: malto-oligosyltrehalose synthase 3 883 1.0E-276 T 14-10-2018 IPR012767 Maltooligosyl trehalose synthase KEGG: 00500+5.4.99.15|MetaCyc: PWY-2661 LH59_19415 a1d83712ad8571081108a15d15d6393e 886 SUPERFAMILY SSF51445 3 784 1.59E-121 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily LH59_19415 a1d83712ad8571081108a15d15d6393e 886 Pfam PF00128 Alpha amylase, catalytic domain 24 97 1.3E-16 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 LH59_19415 a1d83712ad8571081108a15d15d6393e 886 Gene3D G3DSA:3.20.20.80 3 121 5.1E-29 T 14-10-2018 LH59_19415 a1d83712ad8571081108a15d15d6393e 886 Gene3D G3DSA:3.20.20.80 210 379 5.2E-33 T 14-10-2018 LH59_19415 a1d83712ad8571081108a15d15d6393e 886 Gene3D G3DSA:3.20.20.80 629 787 5.8E-34 T 14-10-2018 LH59_27140 813705c930122cb7f4b37b53483e7c3f 311 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 1 307 55.899 T 14-10-2018 IPR023009 Tyrosine recombinase XerC/XerD LH59_27140 813705c930122cb7f4b37b53483e7c3f 311 Gene3D G3DSA:1.10.443.10 104 301 1.6E-53 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 LH59_27140 813705c930122cb7f4b37b53483e7c3f 311 SUPERFAMILY SSF56349 3 302 5.89E-50 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 LH59_27140 813705c930122cb7f4b37b53483e7c3f 311 Pfam PF00589 Phage integrase family 106 293 1.2E-36 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 LH59_27140 813705c930122cb7f4b37b53483e7c3f 311 Gene3D G3DSA:1.10.150.130 1 91 4.7E-14 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal LH59_27140 813705c930122cb7f4b37b53483e7c3f 311 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 3 308 6.2E-106 T 14-10-2018 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007059|GO:0015074|GO:0051301 LH59_27140 813705c930122cb7f4b37b53483e7c3f 311 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 3 78 3.1E-16 T 14-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 LH59_25380 ed28a7bf57a84e01d76889dce25ef4e1 206 Gene3D G3DSA:3.40.30.10 1 83 2.2E-31 T 14-10-2018 LH59_25380 ed28a7bf57a84e01d76889dce25ef4e1 206 SUPERFAMILY SSF47616 72 202 9.33E-29 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily LH59_25380 ed28a7bf57a84e01d76889dce25ef4e1 206 Gene3D G3DSA:1.20.1050.10 84 199 7.9E-40 T 14-10-2018 LH59_25380 ed28a7bf57a84e01d76889dce25ef4e1 206 SUPERFAMILY SSF52833 1 85 2.11E-22 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_25380 ed28a7bf57a84e01d76889dce25ef4e1 206 Pfam PF13417 Glutathione S-transferase, N-terminal domain 8 78 8.1E-13 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 LH59_25380 ed28a7bf57a84e01d76889dce25ef4e1 206 Pfam PF00043 Glutathione S-transferase, C-terminal domain 122 195 5.2E-7 T 14-10-2018 IPR004046 Glutathione S-transferase, C-terminal LH59_22035 ea94bc8dd79c09d0e3b5a1eff705a429 264 SUPERFAMILY SSF161098 59 243 3.66E-31 T 14-10-2018 IPR035906 MetI-like superfamily LH59_22035 ea94bc8dd79c09d0e3b5a1eff705a429 264 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 251 2.4E-24 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_22035 ea94bc8dd79c09d0e3b5a1eff705a429 264 Gene3D G3DSA:1.10.3720.10 57 252 2.8E-25 T 14-10-2018 IPR035906 MetI-like superfamily LH59_16555 6068cb5d8dbfd6c57d6ae5ce2d002669 186 Pfam PF07209 Protein of unknown function (DUF1415) 11 179 4.9E-71 T 14-10-2018 IPR009858 Protein of unknown function DUF1415 LH59_26180 74adb2feffeb7864897a7096c55a681b 709 Gene3D G3DSA:2.170.130.10 69 186 3.0E-31 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily LH59_26180 74adb2feffeb7864897a7096c55a681b 709 Pfam PF07715 TonB-dependent Receptor Plug Domain 72 176 2.1E-20 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_26180 74adb2feffeb7864897a7096c55a681b 709 Pfam PF00593 TonB dependent receptor 344 708 7.4E-44 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_26180 74adb2feffeb7864897a7096c55a681b 709 Gene3D G3DSA:2.40.170.20 188 709 8.1E-64 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_26180 74adb2feffeb7864897a7096c55a681b 709 SUPERFAMILY SSF56935 60 708 2.97E-99 T 14-10-2018 LH59_23335 3b82a5bb08038f608d09c06bb2240f6b 303 TIGRFAM TIGR01433 CyoA: ubiquinol oxidase, subunit II 16 237 2.4E-116 T 14-10-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 LH59_23335 3b82a5bb08038f608d09c06bb2240f6b 303 SUPERFAMILY SSF49503 121 278 4.78E-51 T 14-10-2018 IPR008972 Cupredoxin LH59_23335 3b82a5bb08038f608d09c06bb2240f6b 303 SUPERFAMILY SSF81464 28 116 2.62E-23 T 14-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_23335 3b82a5bb08038f608d09c06bb2240f6b 303 PIRSF PIRSF000292 2 299 1.7E-132 T 14-10-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 LH59_23335 3b82a5bb08038f608d09c06bb2240f6b 303 Pfam PF06481 COX Aromatic Rich Motif 237 281 4.1E-13 T 14-10-2018 IPR010514 COX aromatic rich motif GO:0008827|GO:0016021|GO:0022900|GO:0055114 LH59_23335 3b82a5bb08038f608d09c06bb2240f6b 303 Gene3D G3DSA:2.60.40.420 112 279 5.7E-55 T 14-10-2018 IPR008972 Cupredoxin LH59_23335 3b82a5bb08038f608d09c06bb2240f6b 303 Gene3D G3DSA:1.10.287.90 27 111 1.1E-33 T 14-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_23335 3b82a5bb08038f608d09c06bb2240f6b 303 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 148 218 3.2E-5 T 14-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_05890 1b9ebb8d1287ce5e508733e1ba322ce0 275 SUPERFAMILY SSF56300 3 254 2.04E-43 T 14-10-2018 LH59_05890 1b9ebb8d1287ce5e508733e1ba322ce0 275 Pfam PF00149 Calcineurin-like phosphoesterase 4 151 8.2E-12 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 LH59_05890 1b9ebb8d1287ce5e508733e1ba322ce0 275 TIGRFAM TIGR00668 apaH: bis(5'-nucleosyl)-tetraphosphatase (symmetrical) 5 262 1.4E-67 T 14-10-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 LH59_05890 1b9ebb8d1287ce5e508733e1ba322ce0 275 PIRSF PIRSF000903 2 271 1.1E-83 T 14-10-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 LH59_05890 1b9ebb8d1287ce5e508733e1ba322ce0 275 Gene3D G3DSA:3.60.21.10 3 271 5.8E-69 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like LH59_26605 f8e7420a2b47647657052d240693fb52 181 Pfam PF12802 MarR family 26 80 3.4E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_26605 f8e7420a2b47647657052d240693fb52 181 PIRSF PIRSF006707 1 174 2.2E-54 T 14-10-2018 IPR026282 DNA-binding protein, MJ1563 type LH59_26605 f8e7420a2b47647657052d240693fb52 181 Gene3D G3DSA:1.10.10.10 1 86 5.6E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_26605 f8e7420a2b47647657052d240693fb52 181 SUPERFAMILY SSF46785 4 149 1.84E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_13605 1a3bb152fbbc5865f70e8251d27538f7 216 Gene3D G3DSA:2.60.120.10 97 199 1.2E-22 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_13605 1a3bb152fbbc5865f70e8251d27538f7 216 SUPERFAMILY SSF47413 17 81 2.2E-14 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 LH59_13605 1a3bb152fbbc5865f70e8251d27538f7 216 Gene3D G3DSA:1.10.260.40 16 96 3.7E-14 T 14-10-2018 LH59_13605 1a3bb152fbbc5865f70e8251d27538f7 216 SMART SM00530 23 78 1.2E-10 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LH59_13605 1a3bb152fbbc5865f70e8251d27538f7 216 Pfam PF07883 Cupin domain 142 199 1.8E-9 T 14-10-2018 IPR013096 Cupin 2, conserved barrel LH59_13605 1a3bb152fbbc5865f70e8251d27538f7 216 SUPERFAMILY SSF51182 105 199 1.22E-20 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_13605 1a3bb152fbbc5865f70e8251d27538f7 216 Pfam PF01381 Helix-turn-helix 24 76 2.8E-11 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LH59_12725 4bad4bdc89bc44a79bf5454ae50812a3 589 Pfam PF00990 Diguanylate cyclase, GGDEF domain 405 502 8.6E-12 T 14-10-2018 IPR000160 GGDEF domain LH59_12725 4bad4bdc89bc44a79bf5454ae50812a3 589 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 424 495 6.0E-11 T 14-10-2018 IPR000160 GGDEF domain LH59_12725 4bad4bdc89bc44a79bf5454ae50812a3 589 SMART SM00052 1 238 3.7E-23 T 14-10-2018 IPR001633 EAL domain LH59_12725 4bad4bdc89bc44a79bf5454ae50812a3 589 Pfam PF00571 CBS domain 284 317 1.5E-4 T 14-10-2018 IPR000644 CBS domain LH59_12725 4bad4bdc89bc44a79bf5454ae50812a3 589 SUPERFAMILY SSF141868 4 233 3.27E-51 T 14-10-2018 IPR035919 EAL domain superfamily LH59_12725 4bad4bdc89bc44a79bf5454ae50812a3 589 Pfam PF00563 EAL domain 6 233 1.3E-44 T 14-10-2018 IPR001633 EAL domain LH59_12725 4bad4bdc89bc44a79bf5454ae50812a3 589 SUPERFAMILY SSF55073 406 506 3.14E-17 T 14-10-2018 IPR029787 Nucleotide cyclase LH59_12725 4bad4bdc89bc44a79bf5454ae50812a3 589 Gene3D G3DSA:3.10.580.10 266 403 3.3E-9 T 14-10-2018 LH59_12725 4bad4bdc89bc44a79bf5454ae50812a3 589 SUPERFAMILY SSF54631 274 405 4.13E-10 T 14-10-2018 LH59_12725 4bad4bdc89bc44a79bf5454ae50812a3 589 Gene3D G3DSA:3.20.20.450 3 245 1.3E-54 T 14-10-2018 IPR035919 EAL domain superfamily LH59_12725 4bad4bdc89bc44a79bf5454ae50812a3 589 Gene3D G3DSA:3.30.70.270 404 578 6.5E-18 T 14-10-2018 LH59_12725 4bad4bdc89bc44a79bf5454ae50812a3 589 SMART SM00267 389 576 7.9E-6 T 14-10-2018 IPR000160 GGDEF domain LH59_18315 f8799226c7a2bd2ec9b0860753375fbf 288 SUPERFAMILY SSF51556 19 286 3.4E-64 T 14-10-2018 IPR032466 Metal-dependent hydrolase LH59_18315 f8799226c7a2bd2ec9b0860753375fbf 288 Gene3D G3DSA:3.20.20.140 8 288 7.6E-74 T 14-10-2018 LH59_18315 f8799226c7a2bd2ec9b0860753375fbf 288 Pfam PF04909 Amidohydrolase 23 286 3.5E-33 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 LH59_20610 72d0df76c649d750ee682ee7058bcf84 215 Pfam PF02163 Peptidase family M50 134 179 1.8E-7 T 14-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 LH59_05770 e59591fe62b2cc12e86f5855ce61b1a4 546 Gene3D G3DSA:1.10.287.950 227 526 1.6E-71 T 14-10-2018 LH59_05770 e59591fe62b2cc12e86f5855ce61b1a4 546 Pfam PF12729 Four helix bundle sensory module for signal transduction 18 189 1.8E-7 T 14-10-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain LH59_05770 e59591fe62b2cc12e86f5855ce61b1a4 546 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 336 491 9.4E-44 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 LH59_05770 e59591fe62b2cc12e86f5855ce61b1a4 546 SMART SM00283 277 524 6.4E-70 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 LH59_05770 e59591fe62b2cc12e86f5855ce61b1a4 546 SUPERFAMILY SSF58104 254 525 3.01E-59 T 14-10-2018 LH59_05770 e59591fe62b2cc12e86f5855ce61b1a4 546 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 298 327 2.3E-42 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_05770 e59591fe62b2cc12e86f5855ce61b1a4 546 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 452 481 2.3E-42 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_05770 e59591fe62b2cc12e86f5855ce61b1a4 546 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 404 433 2.3E-42 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_05770 e59591fe62b2cc12e86f5855ce61b1a4 546 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 375 402 2.3E-42 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_07515 6fc9c97aab3d6edcad9daf274c6f346a 157 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 34 144 3.7E-26 T 14-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 LH59_07515 6fc9c97aab3d6edcad9daf274c6f346a 157 SUPERFAMILY SSF54637 14 141 1.47E-30 T 14-10-2018 IPR029069 HotDog domain superfamily LH59_07515 6fc9c97aab3d6edcad9daf274c6f346a 157 TIGRFAM TIGR02286 PaaD: phenylacetic acid degradation protein PaaD 34 146 2.7E-48 T 14-10-2018 IPR011973 Phenylacetic acid degradation protein PaaD GO:0016790 LH59_07515 6fc9c97aab3d6edcad9daf274c6f346a 157 Gene3D G3DSA:3.10.129.10 17 156 3.4E-54 T 14-10-2018 LH59_07515 6fc9c97aab3d6edcad9daf274c6f346a 157 Pfam PF03061 Thioesterase superfamily 63 136 9.8E-13 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 LH59_21370 9663994ef04118c44217e6ae151f873e 414 Pfam PF02515 CoA-transferase family III 12 377 9.6E-107 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 LH59_21370 9663994ef04118c44217e6ae151f873e 414 Gene3D G3DSA:3.40.50.10540 12 394 7.3E-113 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily LH59_21370 9663994ef04118c44217e6ae151f873e 414 Gene3D G3DSA:3.30.1540.10 236 329 7.3E-113 T 14-10-2018 LH59_21370 9663994ef04118c44217e6ae151f873e 414 SUPERFAMILY SSF89796 7 399 7.19E-118 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily LH59_27560 65a074153b3c8c772f06d1a92eea0c12 121 Pfam PF13663 Domain of unknown function (DUF4148) 87 117 3.8E-6 T 14-10-2018 IPR025421 Protein of unknown function DUF4148 LH59_27560 65a074153b3c8c772f06d1a92eea0c12 121 Pfam PF13663 Domain of unknown function (DUF4148) 2 46 1.0E-9 T 14-10-2018 IPR025421 Protein of unknown function DUF4148 LH59_01115 26087184507e86a8859900a7f373f30c 923 Gene3D G3DSA:2.60.120.10 696 827 1.6E-24 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_01115 26087184507e86a8859900a7f373f30c 923 SMART SM00100 703 819 1.7E-9 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain LH59_01115 26087184507e86a8859900a7f373f30c 923 Pfam PF00999 Sodium/hydrogen exchanger family 14 413 2.0E-63 T 14-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 LH59_01115 26087184507e86a8859900a7f373f30c 923 SUPERFAMILY SSF51206 695 820 1.3E-23 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like LH59_01115 26087184507e86a8859900a7f373f30c 923 Pfam PF00027 Cyclic nucleotide-binding domain 726 804 1.8E-11 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain LH59_18695 bfd8a3190601896c433a4c83f8b107bf 300 SUPERFAMILY SSF46785 7 112 7.81E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_18695 bfd8a3190601896c433a4c83f8b107bf 300 Gene3D G3DSA:1.10.10.10 3 88 1.8E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_18695 bfd8a3190601896c433a4c83f8b107bf 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 1.6E-15 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_18695 bfd8a3190601896c433a4c83f8b107bf 300 Pfam PF03466 LysR substrate binding domain 88 292 7.5E-45 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_18695 bfd8a3190601896c433a4c83f8b107bf 300 SUPERFAMILY SSF53850 89 295 1.36E-45 T 14-10-2018 LH59_18695 bfd8a3190601896c433a4c83f8b107bf 300 Gene3D G3DSA:3.40.190.10 91 290 1.8E-61 T 14-10-2018 LH59_18695 bfd8a3190601896c433a4c83f8b107bf 300 Gene3D G3DSA:3.40.190.10 163 263 1.8E-61 T 14-10-2018 LH59_00490 f062cda4320a05b63f930ab8ea947749 181 Gene3D G3DSA:1.10.1740.10 3 76 3.8E-12 T 14-10-2018 LH59_00490 f062cda4320a05b63f930ab8ea947749 181 SUPERFAMILY SSF88659 115 176 1.07E-14 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like LH59_00490 f062cda4320a05b63f930ab8ea947749 181 SUPERFAMILY SSF88946 8 94 8.63E-15 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 LH59_00490 f062cda4320a05b63f930ab8ea947749 181 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 8 175 1.4E-26 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 LH59_00490 f062cda4320a05b63f930ab8ea947749 181 Pfam PF04542 Sigma-70 region 2 19 79 4.2E-12 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 LH59_00490 f062cda4320a05b63f930ab8ea947749 181 Pfam PF08281 Sigma-70, region 4 120 172 4.5E-16 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LH59_00490 f062cda4320a05b63f930ab8ea947749 181 Gene3D G3DSA:1.10.10.10 102 178 3.3E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_13895 7887f9e7a5a1d28ebeb9ead818bc4008 276 SUPERFAMILY SSF161098 71 256 4.97E-21 T 14-10-2018 IPR035906 MetI-like superfamily LH59_13895 7887f9e7a5a1d28ebeb9ead818bc4008 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 274 5.6E-19 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_13895 7887f9e7a5a1d28ebeb9ead818bc4008 276 Gene3D G3DSA:1.10.3720.10 64 271 2.5E-17 T 14-10-2018 IPR035906 MetI-like superfamily LH59_04590 c5eb39ec2617f0401e95d2a0f5ed4756 648 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 97 103 - T 14-10-2018 IPR014762 DNA mismatch repair, conserved site LH59_04590 c5eb39ec2617f0401e95d2a0f5ed4756 648 SMART SM00853 461 604 3.2E-53 T 14-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 LH59_04590 c5eb39ec2617f0401e95d2a0f5ed4756 648 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 7 306 3.1E-88 T 14-10-2018 IPR002099 DNA mismatch repair protein family, N-terminal GO:0005524|GO:0006298|GO:0030983 LH59_04590 c5eb39ec2617f0401e95d2a0f5ed4756 648 Gene3D G3DSA:3.30.1370.100 504 599 3.2E-59 T 14-10-2018 LH59_04590 c5eb39ec2617f0401e95d2a0f5ed4756 648 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 5 644 27.167 T 14-10-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 LH59_04590 c5eb39ec2617f0401e95d2a0f5ed4756 648 Gene3D G3DSA:2.30.42.20 463 641 3.2E-59 T 14-10-2018 LH59_04590 c5eb39ec2617f0401e95d2a0f5ed4756 648 Pfam PF08676 MutL C terminal dimerisation domain 457 604 1.5E-48 T 14-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 LH59_04590 c5eb39ec2617f0401e95d2a0f5ed4756 648 Gene3D G3DSA:3.30.230.10 213 325 2.4E-36 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup LH59_04590 c5eb39ec2617f0401e95d2a0f5ed4756 648 SMART SM01340 208 326 9.3E-55 T 14-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 LH59_04590 c5eb39ec2617f0401e95d2a0f5ed4756 648 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 208 325 3.7E-37 T 14-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 LH59_04590 c5eb39ec2617f0401e95d2a0f5ed4756 648 SUPERFAMILY SSF54211 196 326 7.97E-34 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold LH59_04590 c5eb39ec2617f0401e95d2a0f5ed4756 648 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 28 127 7.6E-11 T 14-10-2018 LH59_04590 c5eb39ec2617f0401e95d2a0f5ed4756 648 SUPERFAMILY SSF55874 5 203 6.16E-51 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_04590 c5eb39ec2617f0401e95d2a0f5ed4756 648 Gene3D G3DSA:3.30.565.10 6 209 2.5E-62 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_04590 c5eb39ec2617f0401e95d2a0f5ed4756 648 SUPERFAMILY SSF118116 456 646 4.45E-58 T 14-10-2018 IPR037198 MutL, C-terminal domain superfamily LH59_22520 40458177c0e54e3d88cd3e8b6088ef3c 204 SUPERFAMILY SSF52833 1 86 1.58E-22 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_22520 40458177c0e54e3d88cd3e8b6088ef3c 204 Pfam PF02798 Glutathione S-transferase, N-terminal domain 2 76 3.6E-16 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 LH59_22520 40458177c0e54e3d88cd3e8b6088ef3c 204 Gene3D G3DSA:3.40.30.10 4 192 2.7E-46 T 14-10-2018 LH59_22520 40458177c0e54e3d88cd3e8b6088ef3c 204 Pfam PF13410 Glutathione S-transferase, C-terminal domain 135 183 3.6E-6 T 14-10-2018 LH59_22520 40458177c0e54e3d88cd3e8b6088ef3c 204 Gene3D G3DSA:1.20.1050.10 84 188 2.7E-46 T 14-10-2018 LH59_22520 40458177c0e54e3d88cd3e8b6088ef3c 204 SUPERFAMILY SSF47616 86 197 3.2E-16 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily LH59_06730 9fc9f833caa827f3341feda424815188 217 Pfam PF01144 Coenzyme A transferase 7 205 4.8E-40 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 LH59_06730 9fc9f833caa827f3341feda424815188 217 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 3 212 3.3E-96 T 14-10-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 LH59_06730 9fc9f833caa827f3341feda424815188 217 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 44 52 - T 14-10-2018 IPR004164 Coenzyme A transferase active site GO:0008410 Reactome: R-HSA-77108 LH59_06730 9fc9f833caa827f3341feda424815188 217 SUPERFAMILY SSF100950 3 214 1.06E-70 T 14-10-2018 IPR037171 NagB/RpiA transferase-like LH59_06730 9fc9f833caa827f3341feda424815188 217 Gene3D G3DSA:3.40.1080.10 2 217 3.3E-99 T 14-10-2018 LH59_06730 9fc9f833caa827f3341feda424815188 217 SMART SM00882 6 206 5.9E-81 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 LH59_23695 9e93de6a67a91294ca6f0c6cb35a47ab 442 PIRSF PIRSF000521 10 127 2.1E-7 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LH59_23695 9e93de6a67a91294ca6f0c6cb35a47ab 442 PIRSF PIRSF000521 123 430 3.0E-25 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LH59_23695 9e93de6a67a91294ca6f0c6cb35a47ab 442 SUPERFAMILY SSF53383 13 429 1.95E-108 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_23695 9e93de6a67a91294ca6f0c6cb35a47ab 442 Gene3D G3DSA:3.40.640.10 57 322 1.3E-125 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_23695 9e93de6a67a91294ca6f0c6cb35a47ab 442 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 238 275 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LH59_23695 9e93de6a67a91294ca6f0c6cb35a47ab 442 Pfam PF00202 Aminotransferase class-III 22 427 5.5E-79 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LH59_23695 9e93de6a67a91294ca6f0c6cb35a47ab 442 Gene3D G3DSA:3.90.1150.10 28 422 1.3E-125 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_08080 e1e96de04ca3f9fba53be0a07655c1fa 625 Pfam PF02653 Branched-chain amino acid transport system / permease component 339 599 4.8E-41 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_08080 e1e96de04ca3f9fba53be0a07655c1fa 625 Pfam PF02653 Branched-chain amino acid transport system / permease component 17 283 6.3E-36 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_02360 33af891131c6e6677eff19f7892b8867 337 Gene3D G3DSA:3.40.190.150 43 327 3.3E-99 T 14-10-2018 LH59_02360 33af891131c6e6677eff19f7892b8867 337 SUPERFAMILY SSF53850 129 301 1.63E-15 T 14-10-2018 LH59_02360 33af891131c6e6677eff19f7892b8867 337 Gene3D G3DSA:3.40.190.10 141 262 3.3E-99 T 14-10-2018 LH59_02360 33af891131c6e6677eff19f7892b8867 337 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 63 333 2.0E-66 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_02360 33af891131c6e6677eff19f7892b8867 337 PIRSF PIRSF017082 10 336 4.5E-77 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_18875 b8e046bb579a46e0012ea243a382e193 264 Gene3D G3DSA:3.40.50.300 4 250 1.5E-61 T 14-10-2018 LH59_18875 b8e046bb579a46e0012ea243a382e193 264 Pfam PF00005 ABC transporter 28 168 1.8E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_18875 b8e046bb579a46e0012ea243a382e193 264 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_18875 b8e046bb579a46e0012ea243a382e193 264 SMART SM00382 36 218 4.4E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_18875 b8e046bb579a46e0012ea243a382e193 264 SUPERFAMILY SSF52540 6 233 6.37E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_18875 b8e046bb579a46e0012ea243a382e193 264 TIGRFAM TIGR01184 ntrCD: nitrate ABC transporter, ATP-binding proteins C and D 28 256 1.2E-88 T 14-10-2018 IPR005890 Nitrate transport ATP-binding subunit C/D GO:0015112|GO:0015706|GO:0016020 LH59_26840 ab6116f09ab4c5c3cb2d63a054714b5b 142 SUPERFAMILY SSF82784 1 141 7.72E-44 T 14-10-2018 IPR036102 OsmC/Ohr superfamily LH59_26840 ab6116f09ab4c5c3cb2d63a054714b5b 142 Pfam PF02566 OsmC-like protein 44 138 2.6E-15 T 14-10-2018 IPR003718 OsmC/Ohr family LH59_26840 ab6116f09ab4c5c3cb2d63a054714b5b 142 Gene3D G3DSA:2.20.25.10 1 47 4.0E-23 T 14-10-2018 LH59_26840 ab6116f09ab4c5c3cb2d63a054714b5b 142 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 7 139 8.8E-54 T 14-10-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 LH59_26840 ab6116f09ab4c5c3cb2d63a054714b5b 142 Gene3D G3DSA:3.30.300.20 48 141 1.6E-32 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta LH59_24555 8751946943ce101b6dd690a5374bb8e6 532 SMART SM00283 262 509 2.7E-95 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 LH59_24555 8751946943ce101b6dd690a5374bb8e6 532 Gene3D G3DSA:1.20.120.30 22 183 2.5E-17 T 14-10-2018 LH59_24555 8751946943ce101b6dd690a5374bb8e6 532 Pfam PF02203 Tar ligand binding domain homologue 1 165 1.1E-31 T 14-10-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 LH59_24555 8751946943ce101b6dd690a5374bb8e6 532 Pfam PF00672 HAMP domain 209 258 9.3E-9 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_24555 8751946943ce101b6dd690a5374bb8e6 532 SMART SM00304 209 261 8.1E-11 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 LH59_24555 8751946943ce101b6dd690a5374bb8e6 532 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 323 477 3.1E-54 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 LH59_24555 8751946943ce101b6dd690a5374bb8e6 532 Gene3D G3DSA:1.10.287.950 209 511 1.7E-91 T 14-10-2018 LH59_24555 8751946943ce101b6dd690a5374bb8e6 532 SUPERFAMILY SSF58104 229 510 7.98E-74 T 14-10-2018 LH59_24555 8751946943ce101b6dd690a5374bb8e6 532 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 283 312 8.6E-70 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_24555 8751946943ce101b6dd690a5374bb8e6 532 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 5 30 8.6E-70 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_24555 8751946943ce101b6dd690a5374bb8e6 532 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 61 76 8.6E-70 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_24555 8751946943ce101b6dd690a5374bb8e6 532 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 360 387 8.6E-70 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_24555 8751946943ce101b6dd690a5374bb8e6 532 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 389 418 8.6E-70 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_24555 8751946943ce101b6dd690a5374bb8e6 532 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 437 466 8.6E-70 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_24555 8751946943ce101b6dd690a5374bb8e6 532 SUPERFAMILY SSF47170 26 173 3.14E-19 T 14-10-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain superfamily LH59_20965 96f3cf3651d0978f3b994c1fe9305f70 316 Pfam PF00326 Prolyl oligopeptidase family 222 309 2.5E-8 T 14-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 LH59_20965 96f3cf3651d0978f3b994c1fe9305f70 316 SUPERFAMILY SSF53474 22 309 1.3E-29 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_20965 96f3cf3651d0978f3b994c1fe9305f70 316 Gene3D G3DSA:3.40.50.1820 15 310 6.6E-26 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_08065 60bbf23e61faeeba34592127fc0a2433 259 Gene3D G3DSA:3.40.50.720 2 259 1.2E-78 T 14-10-2018 LH59_08065 60bbf23e61faeeba34592127fc0a2433 259 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 15 199 4.4E-4 T 14-10-2018 LH59_08065 60bbf23e61faeeba34592127fc0a2433 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 255 1.4E-63 T 14-10-2018 LH59_08065 60bbf23e61faeeba34592127fc0a2433 259 SUPERFAMILY SSF51735 10 257 2.16E-77 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_08065 60bbf23e61faeeba34592127fc0a2433 259 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 150 178 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LH59_08065 60bbf23e61faeeba34592127fc0a2433 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 90 101 1.6E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_08065 60bbf23e61faeeba34592127fc0a2433 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 1.6E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_08065 60bbf23e61faeeba34592127fc0a2433 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 163 182 1.6E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_08065 60bbf23e61faeeba34592127fc0a2433 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 3.2E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_08065 60bbf23e61faeeba34592127fc0a2433 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 3.2E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_08065 60bbf23e61faeeba34592127fc0a2433 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 3.2E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_08065 60bbf23e61faeeba34592127fc0a2433 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 3.2E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_08065 60bbf23e61faeeba34592127fc0a2433 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 3.2E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_08065 60bbf23e61faeeba34592127fc0a2433 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 3.2E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_07825 5dcded6d545206835856c24383c81cf0 151 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 47 5.1E-22 T 14-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_07825 5dcded6d545206835856c24383c81cf0 151 SUPERFAMILY SSF55653 59 148 1.31E-22 T 14-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily LH59_07825 5dcded6d545206835856c24383c81cf0 151 SUPERFAMILY SSF55658 1 56 2.62E-18 T 14-10-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal LH59_07825 5dcded6d545206835856c24383c81cf0 151 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 149 25.576 T 14-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_07825 5dcded6d545206835856c24383c81cf0 151 Gene3D G3DSA:3.40.5.10 1 62 1.2E-22 T 14-10-2018 IPR036935 Ribosomal protein L9, N-terminal domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_07825 5dcded6d545206835856c24383c81cf0 151 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 147 8.0E-24 T 14-10-2018 IPR020069 Ribosomal protein L9, C-terminal LH59_07825 5dcded6d545206835856c24383c81cf0 151 Gene3D G3DSA:3.10.430.100 63 149 1.3E-24 T 14-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily LH59_07825 5dcded6d545206835856c24383c81cf0 151 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 14-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_07825 5dcded6d545206835856c24383c81cf0 151 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 147 2.3E-41 T 14-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_17690 ce4a59c6e97ce67c7bbc60f97c7bb5ed 221 Gene3D G3DSA:3.40.50.170 3 210 2.6E-78 T 14-10-2018 LH59_17690 ce4a59c6e97ce67c7bbc60f97c7bb5ed 221 SUPERFAMILY SSF53328 10 208 1.31E-64 T 14-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 LH59_17690 ce4a59c6e97ce67c7bbc60f97c7bb5ed 221 Pfam PF00551 Formyl transferase 10 189 1.1E-59 T 14-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 LH59_17690 ce4a59c6e97ce67c7bbc60f97c7bb5ed 221 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 10 195 31.518 T 14-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 LH59_17690 ce4a59c6e97ce67c7bbc60f97c7bb5ed 221 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 10 198 5.9E-75 T 14-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 LH59_03320 931076e004a27b7a76f96271cfe1588c 225 SUPERFAMILY SSF53474 15 224 2.68E-50 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_03320 931076e004a27b7a76f96271cfe1588c 225 Gene3D G3DSA:3.40.50.1820 5 225 4.9E-66 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_03320 931076e004a27b7a76f96271cfe1588c 225 Pfam PF02230 Phospholipase/Carboxylesterase 11 223 9.2E-49 T 14-10-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 LH59_04485 db6d1c186217e7dc46e05b4b746b70f6 327 PIRSF PIRSF017082 4 326 6.1E-76 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_04485 db6d1c186217e7dc46e05b4b746b70f6 327 SUPERFAMILY SSF53850 112 287 1.63E-15 T 14-10-2018 LH59_04485 db6d1c186217e7dc46e05b4b746b70f6 327 Gene3D G3DSA:3.40.190.150 32 317 1.1E-110 T 14-10-2018 LH59_04485 db6d1c186217e7dc46e05b4b746b70f6 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 323 4.3E-84 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_04485 db6d1c186217e7dc46e05b4b746b70f6 327 Gene3D G3DSA:3.40.190.10 129 252 1.1E-110 T 14-10-2018 LH59_22185 5354e7218f4efaf27374fd68b3eec7a9 301 Gene3D G3DSA:1.10.10.10 6 86 7.8E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_22185 5354e7218f4efaf27374fd68b3eec7a9 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 66 8.8E-19 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_22185 5354e7218f4efaf27374fd68b3eec7a9 301 SUPERFAMILY SSF46785 5 82 8.11E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_22185 5354e7218f4efaf27374fd68b3eec7a9 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 6.2E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_22185 5354e7218f4efaf27374fd68b3eec7a9 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 6.2E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_22185 5354e7218f4efaf27374fd68b3eec7a9 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 6.2E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_22185 5354e7218f4efaf27374fd68b3eec7a9 301 Pfam PF03466 LysR substrate binding domain 93 295 9.1E-32 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_22185 5354e7218f4efaf27374fd68b3eec7a9 301 Gene3D G3DSA:3.40.190.10 104 291 5.5E-46 T 14-10-2018 LH59_22185 5354e7218f4efaf27374fd68b3eec7a9 301 Gene3D G3DSA:3.40.190.10 164 264 5.5E-46 T 14-10-2018 LH59_22185 5354e7218f4efaf27374fd68b3eec7a9 301 SUPERFAMILY SSF53850 93 297 9.91E-33 T 14-10-2018 LH59_19565 3b6e809f7d45e72e3c440252443010a4 227 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 14 111 1.6E-27 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 LH59_19565 3b6e809f7d45e72e3c440252443010a4 227 SUPERFAMILY SSF161098 14 202 4.71E-42 T 14-10-2018 IPR035906 MetI-like superfamily LH59_19565 3b6e809f7d45e72e3c440252443010a4 227 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 206 3.2E-19 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_19565 3b6e809f7d45e72e3c440252443010a4 227 Gene3D G3DSA:1.10.3720.10 3 216 1.2E-51 T 14-10-2018 IPR035906 MetI-like superfamily LH59_18775 5082076cf20728fa3c86415ccc9264d3 369 Gene3D G3DSA:2.102.10.10 40 161 2.8E-44 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 LH59_18775 5082076cf20728fa3c86415ccc9264d3 369 SUPERFAMILY SSF55961 160 366 9.42E-31 T 14-10-2018 LH59_18775 5082076cf20728fa3c86415ccc9264d3 369 Pfam PF00355 Rieske [2Fe-2S] domain 46 126 5.4E-15 T 14-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 LH59_18775 5082076cf20728fa3c86415ccc9264d3 369 Gene3D G3DSA:3.90.380.10 232 355 4.9E-5 T 14-10-2018 LH59_18775 5082076cf20728fa3c86415ccc9264d3 369 SUPERFAMILY SSF50022 11 153 1.83E-40 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 LH59_18775 5082076cf20728fa3c86415ccc9264d3 369 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 178 367 2.1E-27 T 14-10-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0044237|GO:0051537|GO:0055114 LH59_18775 5082076cf20728fa3c86415ccc9264d3 369 Gene3D G3DSA:3.90.380.10 20 215 2.8E-44 T 14-10-2018 LH59_18775 5082076cf20728fa3c86415ccc9264d3 369 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 57 72 1.7E-13 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 LH59_18775 5082076cf20728fa3c86415ccc9264d3 369 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 78 98 1.7E-13 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 LH59_18775 5082076cf20728fa3c86415ccc9264d3 369 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 99 119 1.7E-13 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 LH59_18775 5082076cf20728fa3c86415ccc9264d3 369 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 27 52 1.7E-13 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 LH59_18775 5082076cf20728fa3c86415ccc9264d3 369 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 85 108 - T 14-10-2018 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0051537|GO:0055114 LH59_13790 d1dedc405b07d0760aa3fdb78b3fa976 244 Pfam PF03358 NADPH-dependent FMN reductase 39 181 3.2E-26 T 14-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 LH59_13790 d1dedc405b07d0760aa3fdb78b3fa976 244 SUPERFAMILY SSF52218 10 231 4.79E-63 T 14-10-2018 IPR029039 Flavoprotein-like superfamily LH59_13790 d1dedc405b07d0760aa3fdb78b3fa976 244 Gene3D G3DSA:3.40.50.360 7 244 2.6E-74 T 14-10-2018 IPR029039 Flavoprotein-like superfamily LH59_13790 d1dedc405b07d0760aa3fdb78b3fa976 244 TIGRFAM TIGR02690 resist_ArsH: arsenical resistance protein ArsH 12 230 1.9E-126 T 14-10-2018 IPR014063 Arsenate resistance ArsH LH59_00115 5908831b4f419671269cd9c6f235b4f7 295 Gene3D G3DSA:1.10.3720.10 20 292 1.3E-59 T 14-10-2018 IPR035906 MetI-like superfamily LH59_00115 5908831b4f419671269cd9c6f235b4f7 295 SUPERFAMILY SSF161098 20 290 2.22E-55 T 14-10-2018 IPR035906 MetI-like superfamily LH59_00115 5908831b4f419671269cd9c6f235b4f7 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 287 1.5E-9 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_26320 14d0468e6ad26265603b385746ed8f50 229 SUPERFAMILY SSF46894 129 220 7.37E-11 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LH59_26320 14d0468e6ad26265603b385746ed8f50 229 Gene3D G3DSA:1.10.10.10 126 222 1.3E-10 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_26320 14d0468e6ad26265603b385746ed8f50 229 SUPERFAMILY SSF52172 7 124 8.42E-7 T 14-10-2018 IPR011006 CheY-like superfamily LH59_26320 14d0468e6ad26265603b385746ed8f50 229 SMART SM00862 145 219 1.5E-5 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_26320 14d0468e6ad26265603b385746ed8f50 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 219 3.4E-6 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_10275 81c872a2fb619aa455f11bfc5a17a4e5 169 SMART SM00903 20 167 5.6E-47 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 LH59_10275 81c872a2fb619aa455f11bfc5a17a4e5 169 Gene3D G3DSA:2.30.110.10 5 169 1.3E-44 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 LH59_10275 81c872a2fb619aa455f11bfc5a17a4e5 169 Pfam PF01613 Flavin reductase like domain 21 167 2.1E-34 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 LH59_10275 81c872a2fb619aa455f11bfc5a17a4e5 169 SUPERFAMILY SSF50475 6 168 1.08E-40 T 14-10-2018 LH59_20760 d3bc0f89bcda71611ca4a1f3fe5425ac 605 SUPERFAMILY SSF48208 195 590 4.16E-108 T 14-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 LH59_20760 d3bc0f89bcda71611ca4a1f3fe5425ac 605 Gene3D G3DSA:1.50.10.10 220 599 8.0E-88 T 14-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 LH59_20760 d3bc0f89bcda71611ca4a1f3fe5425ac 605 Pfam PF00723 Glycosyl hydrolases family 15 218 529 2.3E-60 T 14-10-2018 IPR011613 GH15-like domain Reactome: R-HSA-70221 LH59_27235 a39b81bbeb5d89e039b8fca489c5f8ee 288 Pfam PF01063 Amino-transferase class IV 37 259 1.9E-41 T 14-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 LH59_27235 a39b81bbeb5d89e039b8fca489c5f8ee 288 Gene3D G3DSA:3.20.10.10 128 287 1.9E-53 T 14-10-2018 LH59_27235 a39b81bbeb5d89e039b8fca489c5f8ee 288 Gene3D G3DSA:3.30.470.10 6 126 2.5E-37 T 14-10-2018 LH59_27235 a39b81bbeb5d89e039b8fca489c5f8ee 288 SUPERFAMILY SSF56752 11 281 3.14E-74 T 14-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 LH59_27145 28a416724b000c6b5c6fdd577c6938ce 376 Pfam PF03824 High-affinity nickel-transport protein 85 372 9.4E-58 T 14-10-2018 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 LH59_23400 5eb0450b9e1dfd464653d9b019c5ceba 233 Pfam PF03483 B3/4 domain 60 199 3.5E-19 T 14-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 LH59_23400 5eb0450b9e1dfd464653d9b019c5ceba 233 SMART SM00873 59 210 7.4E-6 T 14-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 LH59_23400 5eb0450b9e1dfd464653d9b019c5ceba 233 Gene3D G3DSA:3.50.40.10 60 206 2.3E-5 T 14-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 LH59_23400 5eb0450b9e1dfd464653d9b019c5ceba 233 SUPERFAMILY SSF56037 50 201 1.54E-28 T 14-10-2018 LH59_24795 c2033268c2f7e9bdaaa1b289259b5a33 469 Pfam PF01425 Amidase 25 446 3.7E-79 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_24795 c2033268c2f7e9bdaaa1b289259b5a33 469 Gene3D G3DSA:3.90.1300.10 1 466 7.7E-119 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_24795 c2033268c2f7e9bdaaa1b289259b5a33 469 SUPERFAMILY SSF75304 3 455 3.27E-116 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_28065 3f4841565ba459d9d68a76586fbccf40 560 Gene3D G3DSA:1.10.3720.10 304 554 1.0E-20 T 14-10-2018 IPR035906 MetI-like superfamily LH59_28065 3f4841565ba459d9d68a76586fbccf40 560 SUPERFAMILY SSF161098 312 543 7.59E-24 T 14-10-2018 IPR035906 MetI-like superfamily LH59_28065 3f4841565ba459d9d68a76586fbccf40 560 Gene3D G3DSA:1.10.3720.10 23 286 1.8E-57 T 14-10-2018 IPR035906 MetI-like superfamily LH59_28065 3f4841565ba459d9d68a76586fbccf40 560 SUPERFAMILY SSF161098 23 275 2.49E-53 T 14-10-2018 IPR035906 MetI-like superfamily LH59_28065 3f4841565ba459d9d68a76586fbccf40 560 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 279 6.5E-13 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_05945 4de49b64c7fd1b3bebe87b872f74a1dc 141 SUPERFAMILY SSF54909 64 139 1.47E-12 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel LH59_05945 4de49b64c7fd1b3bebe87b872f74a1dc 141 SMART SM00344 1 107 9.1E-17 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 LH59_05945 4de49b64c7fd1b3bebe87b872f74a1dc 141 Pfam PF01037 Lrp/AsnC ligand binding domain 68 136 1.1E-10 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LH59_05945 4de49b64c7fd1b3bebe87b872f74a1dc 141 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 47 2.3E-13 T 14-10-2018 LH59_05945 4de49b64c7fd1b3bebe87b872f74a1dc 141 SUPERFAMILY SSF46785 1 57 3.0E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_05945 4de49b64c7fd1b3bebe87b872f74a1dc 141 Gene3D G3DSA:3.30.70.920 54 141 9.3E-14 T 14-10-2018 LH59_05945 4de49b64c7fd1b3bebe87b872f74a1dc 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 9.1E-11 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_05945 4de49b64c7fd1b3bebe87b872f74a1dc 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 9.1E-11 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_05945 4de49b64c7fd1b3bebe87b872f74a1dc 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 9.1E-11 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_05945 4de49b64c7fd1b3bebe87b872f74a1dc 141 Gene3D G3DSA:1.10.10.10 1 52 2.4E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_02300 026e22ea39ac24b40a977dff2c41ad76 304 SUPERFAMILY SSF53850 93 295 4.89E-21 T 14-10-2018 LH59_02300 026e22ea39ac24b40a977dff2c41ad76 304 Pfam PF03466 LysR substrate binding domain 90 298 1.4E-23 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_02300 026e22ea39ac24b40a977dff2c41ad76 304 Gene3D G3DSA:1.10.10.10 2 83 1.5E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_02300 026e22ea39ac24b40a977dff2c41ad76 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 1.2E-15 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_02300 026e22ea39ac24b40a977dff2c41ad76 304 SUPERFAMILY SSF46785 3 85 3.59E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_02300 026e22ea39ac24b40a977dff2c41ad76 304 Gene3D G3DSA:3.40.190.10 84 186 2.1E-7 T 14-10-2018 LH59_02300 026e22ea39ac24b40a977dff2c41ad76 304 Gene3D G3DSA:3.40.190.10 218 270 4.6E-7 T 14-10-2018 LH59_04370 1cfe86eb99606811103c851d81fc6538 797 Hamap MF_01411 LPS-assembly protein LptD [lptD]. 3 764 19.321 T 14-10-2018 IPR020889 LPS-assembly protein LptD GO:0009279|GO:0010033|GO:0015920|GO:0043165 LH59_04370 1cfe86eb99606811103c851d81fc6538 797 Gene3D G3DSA:2.60.450.10 17 115 5.5E-5 T 14-10-2018 LH59_04370 1cfe86eb99606811103c851d81fc6538 797 Pfam PF04453 Organic solvent tolerance protein 296 691 2.6E-99 T 14-10-2018 IPR007543 Organic solvent tolerance protein, C-terminal GO:0010033|GO:0019867|GO:0061024 LH59_03920 49f662128d4cf740ee93e15fffa13608 184 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 11 163 5.0E-52 T 14-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 LH59_03920 49f662128d4cf740ee93e15fffa13608 184 SUPERFAMILY SSF55068 6 175 4.32E-70 T 14-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 LH59_03920 49f662128d4cf740ee93e15fffa13608 184 Pfam PF01625 Peptide methionine sulfoxide reductase 12 164 1.2E-58 T 14-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 LH59_03920 49f662128d4cf740ee93e15fffa13608 184 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 9 168 34.544 T 14-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 LH59_03920 49f662128d4cf740ee93e15fffa13608 184 Gene3D G3DSA:3.30.1060.10 1 173 2.6E-64 T 14-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 LH59_10995 af8758848a741bb88160db69f201902f 347 Pfam PF02779 Transketolase, pyrimidine binding domain 13 188 1.8E-44 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain LH59_10995 af8758848a741bb88160db69f201902f 347 SMART SM00861 14 189 9.9E-66 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain LH59_10995 af8758848a741bb88160db69f201902f 347 Pfam PF02780 Transketolase, C-terminal domain 221 337 4.3E-37 T 14-10-2018 IPR033248 Transketolase, C-terminal domain LH59_10995 af8758848a741bb88160db69f201902f 347 Gene3D G3DSA:3.40.50.970 10 213 2.1E-90 T 14-10-2018 LH59_10995 af8758848a741bb88160db69f201902f 347 SUPERFAMILY SSF52922 215 345 3.8E-42 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 LH59_10995 af8758848a741bb88160db69f201902f 347 Gene3D G3DSA:3.40.50.920 214 347 5.0E-57 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 LH59_10995 af8758848a741bb88160db69f201902f 347 SUPERFAMILY SSF52518 12 229 3.85E-67 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold LH59_09965 c5101ebe470d42b75ef5f223fcc8602b 407 SMART SM00825 Beta-ketoacyl synthase 4 406 1.9E-9 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain LH59_09965 c5101ebe470d42b75ef5f223fcc8602b 407 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 155 171 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site LH59_09965 c5101ebe470d42b75ef5f223fcc8602b 407 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2 246 5.0E-45 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal LH59_09965 c5101ebe470d42b75ef5f223fcc8602b 407 SUPERFAMILY SSF53901 1 251 6.05E-59 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_09965 c5101ebe470d42b75ef5f223fcc8602b 407 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 254 363 1.9E-28 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal LH59_09965 c5101ebe470d42b75ef5f223fcc8602b 407 Gene3D G3DSA:3.40.47.10 260 406 6.6E-43 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_09965 c5101ebe470d42b75ef5f223fcc8602b 407 SUPERFAMILY SSF53901 217 406 2.97E-60 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_09965 c5101ebe470d42b75ef5f223fcc8602b 407 Gene3D G3DSA:3.40.47.10 5 259 1.8E-61 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_26350 8de329400ce22d1588ef9c12af4533f7 396 SMART SM00267 206 378 2.6E-53 T 14-10-2018 IPR000160 GGDEF domain LH59_26350 8de329400ce22d1588ef9c12af4533f7 396 Pfam PF00990 Diguanylate cyclase, GGDEF domain 217 373 1.5E-40 T 14-10-2018 IPR000160 GGDEF domain LH59_26350 8de329400ce22d1588ef9c12af4533f7 396 Gene3D G3DSA:3.30.70.270 212 379 8.0E-50 T 14-10-2018 LH59_26350 8de329400ce22d1588ef9c12af4533f7 396 SUPERFAMILY SSF55073 222 377 3.92E-43 T 14-10-2018 IPR029787 Nucleotide cyclase LH59_26350 8de329400ce22d1588ef9c12af4533f7 396 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 214 377 2.8E-41 T 14-10-2018 IPR000160 GGDEF domain LH59_07005 1f2f8d730512e0a3f539597a5d491591 210 Pfam PF10670 Domain of unknown function (DUF4198) 87 183 1.7E-11 T 14-10-2018 IPR019613 Protein of unknown function DUF4198 LH59_07005 1f2f8d730512e0a3f539597a5d491591 210 SUPERFAMILY SSF49478 133 182 1.73E-5 T 14-10-2018 LH59_06955 7ea231b883ef3c8d14d2a43c2b53fd38 314 SUPERFAMILY SSF88713 10 311 1.0E-91 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 LH59_06955 7ea231b883ef3c8d14d2a43c2b53fd38 314 Pfam PF01522 Polysaccharide deacetylase 80 167 3.7E-12 T 14-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 LH59_06955 7ea231b883ef3c8d14d2a43c2b53fd38 314 Gene3D G3DSA:3.20.20.370 2 314 1.7E-111 T 14-10-2018 LH59_06955 7ea231b883ef3c8d14d2a43c2b53fd38 314 TIGRFAM TIGR03212 uraD_N-term-dom: putative urate catabolism protein 10 310 1.5E-153 T 14-10-2018 IPR017625 PuuE allantoinase/chitin deacetylase 1 LH59_08885 0ed54302751b2dc29f5a6dcbce634dfb 355 Gene3D G3DSA:3.40.718.10 2 353 1.7E-136 T 14-10-2018 LH59_08885 0ed54302751b2dc29f5a6dcbce634dfb 355 SMART SM01329 6 348 3.4E-181 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 LH59_08885 0ed54302751b2dc29f5a6dcbce634dfb 355 TIGRFAM TIGR02089 TTC: tartrate dehydrogenase 4 350 3.0E-170 T 14-10-2018 IPR011829 Tartrate dehydrogenase GO:0016616|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.93|KEGG: 00650+1.1.1.83 LH59_08885 0ed54302751b2dc29f5a6dcbce634dfb 355 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 242 261 - T 14-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 LH59_08885 0ed54302751b2dc29f5a6dcbce634dfb 355 SUPERFAMILY SSF53659 3 351 2.52E-119 T 14-10-2018 LH59_08885 0ed54302751b2dc29f5a6dcbce634dfb 355 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 6 348 3.1E-87 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 LH59_18550 7372c16d759e5898ad2070c8f5d32c60 398 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 202 216 - T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 LH59_18550 7372c16d759e5898ad2070c8f5d32c60 398 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 11 393 6.6E-139 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 LH59_18550 7372c16d759e5898ad2070c8f5d32c60 398 PIRSF PIRSF001434 1 397 8.0E-145 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 LH59_18550 7372c16d759e5898ad2070c8f5d32c60 398 Gene3D G3DSA:3.40.640.10 7 261 6.8E-95 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_18550 7372c16d759e5898ad2070c8f5d32c60 398 SUPERFAMILY SSF53383 29 395 4.84E-120 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_18550 7372c16d759e5898ad2070c8f5d32c60 398 Gene3D G3DSA:3.90.1150.10 262 398 3.7E-50 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_00385 dc42929b7a26badf077a94e50ce8b716 222 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 15 111 5.6E-29 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 LH59_00385 dc42929b7a26badf077a94e50ce8b716 222 SUPERFAMILY SSF161098 15 205 2.29E-40 T 14-10-2018 IPR035906 MetI-like superfamily LH59_00385 dc42929b7a26badf077a94e50ce8b716 222 Gene3D G3DSA:1.10.3720.10 3 219 6.0E-51 T 14-10-2018 IPR035906 MetI-like superfamily LH59_00385 dc42929b7a26badf077a94e50ce8b716 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 216 8.2E-18 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_22840 314ca81fbcdd8be4717b13bafc8b04ba 341 Gene3D G3DSA:3.20.20.70 17 327 4.1E-125 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_22840 314ca81fbcdd8be4717b13bafc8b04ba 341 SUPERFAMILY SSF102114 20 324 9.81E-95 T 14-10-2018 LH59_22840 314ca81fbcdd8be4717b13bafc8b04ba 341 Pfam PF04055 Radical SAM superfamily 63 216 4.9E-17 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 LH59_22840 314ca81fbcdd8be4717b13bafc8b04ba 341 Hamap MF_01694 Biotin synthase [bioB]. 18 326 42.319 T 14-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 LH59_22840 314ca81fbcdd8be4717b13bafc8b04ba 341 SMART SM00876 233 325 2.6E-47 T 14-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 LH59_22840 314ca81fbcdd8be4717b13bafc8b04ba 341 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 233 323 7.3E-19 T 14-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 LH59_22840 314ca81fbcdd8be4717b13bafc8b04ba 341 TIGRFAM TIGR00433 bioB: biotin synthase 27 323 4.0E-123 T 14-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 LH59_22840 314ca81fbcdd8be4717b13bafc8b04ba 341 SMART SM00729 56 268 9.0E-39 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 LH59_22840 314ca81fbcdd8be4717b13bafc8b04ba 341 PIRSF PIRSF001619 10 331 5.1E-132 T 14-10-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 LH59_15145 ae5e1eeb14ddd25c203d6b5068dfd405 633 Gene3D G3DSA:2.40.170.20 7 633 3.0E-149 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_15145 ae5e1eeb14ddd25c203d6b5068dfd405 633 Pfam PF07715 TonB-dependent Receptor Plug Domain 15 121 1.8E-16 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_15145 ae5e1eeb14ddd25c203d6b5068dfd405 633 SUPERFAMILY SSF56935 1 632 1.01E-117 T 14-10-2018 LH59_15145 ae5e1eeb14ddd25c203d6b5068dfd405 633 Pfam PF00593 TonB dependent receptor 199 632 1.6E-42 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_26020 df50f02b0c89deddfc8737604b1a2cc0 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 248 2.8E-63 T 14-10-2018 LH59_26020 df50f02b0c89deddfc8737604b1a2cc0 251 SUPERFAMILY SSF51735 6 250 2.04E-78 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_26020 df50f02b0c89deddfc8737604b1a2cc0 251 Gene3D G3DSA:3.40.50.720 3 251 3.3E-81 T 14-10-2018 LH59_26020 df50f02b0c89deddfc8737604b1a2cc0 251 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 187 0.0011 T 14-10-2018 LH59_26020 df50f02b0c89deddfc8737604b1a2cc0 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 1.9E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_26020 df50f02b0c89deddfc8737604b1a2cc0 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.9E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_26020 df50f02b0c89deddfc8737604b1a2cc0 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 1.9E-13 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_26020 df50f02b0c89deddfc8737604b1a2cc0 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 2.1E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_26020 df50f02b0c89deddfc8737604b1a2cc0 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 2.1E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_26020 df50f02b0c89deddfc8737604b1a2cc0 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 2.1E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_26020 df50f02b0c89deddfc8737604b1a2cc0 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 2.1E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_26020 df50f02b0c89deddfc8737604b1a2cc0 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 2.1E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_26020 df50f02b0c89deddfc8737604b1a2cc0 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.1E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_26020 df50f02b0c89deddfc8737604b1a2cc0 251 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LH59_24595 f7069f88af284a33ffd9a028df304b72 432 Hamap MF_00334 Homogentisate 1,2-dioxygenase [hmgA]. 4 429 70.863 T 14-10-2018 IPR022950 Homogentisate 1,2-dioxygenase, bacterial GO:0004411|GO:0006559|GO:0006572|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5 LH59_24595 f7069f88af284a33ffd9a028df304b72 432 SUPERFAMILY SSF51182 2 429 2.14E-173 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_24595 f7069f88af284a33ffd9a028df304b72 432 TIGRFAM TIGR01015 hmgA: homogentisate 1,2-dioxygenase 2 427 3.0E-200 T 14-10-2018 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 LH59_24595 f7069f88af284a33ffd9a028df304b72 432 Pfam PF04209 homogentisate 1,2-dioxygenase 4 427 6.2E-202 T 14-10-2018 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 LH59_24595 f7069f88af284a33ffd9a028df304b72 432 Gene3D G3DSA:2.60.120.10 270 398 2.5E-59 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_18160 504cadac90fc2a08672786b83489445f 276 Gene3D G3DSA:3.20.20.70 1 252 6.5E-120 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_18160 504cadac90fc2a08672786b83489445f 276 Pfam PF09370 Phosphoenolpyruvate hydrolase-like 9 274 4.1E-132 T 14-10-2018 IPR009215 TIM-barrel domain, IGPS-like LH59_18160 504cadac90fc2a08672786b83489445f 276 SUPERFAMILY SSF51621 3 197 2.89E-85 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 LH59_18160 504cadac90fc2a08672786b83489445f 276 PIRSF PIRSF034452 1 276 1.7E-152 T 14-10-2018 IPR009215 TIM-barrel domain, IGPS-like LH59_18475 f32a105458797c82c177ac125e1e1a98 213 Gene3D G3DSA:1.10.357.10 74 207 2.9E-11 T 14-10-2018 LH59_18475 f32a105458797c82c177ac125e1e1a98 213 ProSitePatterns PS01081 TetR-type HTH domain signature. 44 75 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site LH59_18475 f32a105458797c82c177ac125e1e1a98 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 32 78 6.8E-18 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_18475 f32a105458797c82c177ac125e1e1a98 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 45 6.5E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_18475 f32a105458797c82c177ac125e1e1a98 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 53 76 6.5E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_18475 f32a105458797c82c177ac125e1e1a98 213 SUPERFAMILY SSF48498 101 208 2.22E-5 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily LH59_18475 f32a105458797c82c177ac125e1e1a98 213 SUPERFAMILY SSF46689 20 98 6.98E-19 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_18475 f32a105458797c82c177ac125e1e1a98 213 Gene3D G3DSA:1.10.10.60 3 73 1.4E-18 T 14-10-2018 LH59_01610 6de9028072ebdf996eccd06a5b5dedd5 413 SUPERFAMILY SSF56645 33 237 1.83E-47 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 LH59_01610 6de9028072ebdf996eccd06a5b5dedd5 413 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 254 388 7.0E-19 T 14-10-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain LH59_01610 6de9028072ebdf996eccd06a5b5dedd5 413 Gene3D G3DSA:1.10.540.10 29 135 7.0E-26 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 LH59_01610 6de9028072ebdf996eccd06a5b5dedd5 413 TIGRFAM TIGR04022 sulfur_SfnB: sulfur acquisition oxidoreductase, SfnB family 22 413 4.5E-184 T 14-10-2018 IPR023922 Sulphate-starvation-induced SfnB LH59_01610 6de9028072ebdf996eccd06a5b5dedd5 413 Gene3D G3DSA:1.20.140.10 237 411 1.5E-56 T 14-10-2018 LH59_01610 6de9028072ebdf996eccd06a5b5dedd5 413 SUPERFAMILY SSF47203 251 412 8.54E-23 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 LH59_01610 6de9028072ebdf996eccd06a5b5dedd5 413 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 35 134 8.7E-13 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 LH59_01610 6de9028072ebdf996eccd06a5b5dedd5 413 Gene3D G3DSA:2.40.110.10 137 236 1.9E-28 T 14-10-2018 LH59_01610 6de9028072ebdf996eccd06a5b5dedd5 413 PIRSF PIRSF016578 16 409 2.3E-29 T 14-10-2018 LH59_17100 23737b16c140b4ad5129a89066e66c5c 417 Pfam PF03594 Benzoate membrane transport protein 18 386 2.2E-130 T 14-10-2018 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 LH59_17100 23737b16c140b4ad5129a89066e66c5c 417 TIGRFAM TIGR00843 benE: benzoate transporter 18 387 6.2E-112 T 14-10-2018 IPR004711 Benzoate transporter GO:0016021|GO:0042919|GO:0042925 LH59_21525 1fcab5cbd41467c59dc9fcfc8fbdf75b 426 SUPERFAMILY SSF53720 17 425 6.02E-117 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 LH59_21525 1fcab5cbd41467c59dc9fcfc8fbdf75b 426 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 22 415 5.1E-145 T 14-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 LH59_21525 1fcab5cbd41467c59dc9fcfc8fbdf75b 426 Pfam PF00171 Aldehyde dehydrogenase family 318 381 1.4E-7 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 LH59_21525 1fcab5cbd41467c59dc9fcfc8fbdf75b 426 Pfam PF00171 Aldehyde dehydrogenase family 20 291 5.6E-15 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 LH59_21525 1fcab5cbd41467c59dc9fcfc8fbdf75b 426 Gene3D G3DSA:3.40.309.10 235 383 4.7E-162 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 LH59_21525 1fcab5cbd41467c59dc9fcfc8fbdf75b 426 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 332 353 - T 14-10-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 LH59_21525 1fcab5cbd41467c59dc9fcfc8fbdf75b 426 PIRSF PIRSF000151 7 426 3.5E-174 T 14-10-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 LH59_21525 1fcab5cbd41467c59dc9fcfc8fbdf75b 426 Gene3D G3DSA:3.40.605.10 22 422 4.7E-162 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 LH59_21525 1fcab5cbd41467c59dc9fcfc8fbdf75b 426 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 14 425 41.955 T 14-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 LH59_04170 1efd5e86b83d1087f90462bc2ada71b8 291 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 237 251 - T 14-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 LH59_04170 1efd5e86b83d1087f90462bc2ada71b8 291 Pfam PF00459 Inositol monophosphatase family 21 288 2.0E-58 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 LH59_04170 1efd5e86b83d1087f90462bc2ada71b8 291 SUPERFAMILY SSF56655 19 288 2.36E-74 T 14-10-2018 LH59_04170 1efd5e86b83d1087f90462bc2ada71b8 291 PRINTS PR01959 SuhB family inositol monophosphatase signature 224 236 6.8E-13 T 14-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 LH59_04170 1efd5e86b83d1087f90462bc2ada71b8 291 PRINTS PR01959 SuhB family inositol monophosphatase signature 130 149 6.8E-13 T 14-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 LH59_04170 1efd5e86b83d1087f90462bc2ada71b8 291 PRINTS PR01959 SuhB family inositol monophosphatase signature 182 208 6.8E-13 T 14-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 LH59_04170 1efd5e86b83d1087f90462bc2ada71b8 291 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 94 107 - T 14-10-2018 IPR020583 Inositol monophosphatase, metal-binding site LH59_04170 1efd5e86b83d1087f90462bc2ada71b8 291 PRINTS PR00377 Inositol monophosphatase superfamily signature 53 73 2.5E-48 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 LH59_04170 1efd5e86b83d1087f90462bc2ada71b8 291 PRINTS PR00377 Inositol monophosphatase superfamily signature 156 179 2.5E-48 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 LH59_04170 1efd5e86b83d1087f90462bc2ada71b8 291 PRINTS PR00377 Inositol monophosphatase superfamily signature 75 91 2.5E-48 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 LH59_04170 1efd5e86b83d1087f90462bc2ada71b8 291 PRINTS PR00377 Inositol monophosphatase superfamily signature 203 224 2.5E-48 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 LH59_04170 1efd5e86b83d1087f90462bc2ada71b8 291 PRINTS PR00377 Inositol monophosphatase superfamily signature 234 258 2.5E-48 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 LH59_04170 1efd5e86b83d1087f90462bc2ada71b8 291 PRINTS PR00377 Inositol monophosphatase superfamily signature 94 110 2.5E-48 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 LH59_04170 1efd5e86b83d1087f90462bc2ada71b8 291 Gene3D G3DSA:3.30.540.10 13 166 1.7E-42 T 14-10-2018 LH59_04170 1efd5e86b83d1087f90462bc2ada71b8 291 Gene3D G3DSA:3.40.190.80 167 289 1.7E-35 T 14-10-2018 LH59_20470 3d8f3ed07ceed1cbb816a3efba3da5c6 273 Pfam PF00005 ABC transporter 43 181 6.2E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_20470 3d8f3ed07ceed1cbb816a3efba3da5c6 273 Gene3D G3DSA:3.40.50.300 25 253 8.7E-60 T 14-10-2018 LH59_20470 3d8f3ed07ceed1cbb816a3efba3da5c6 273 SUPERFAMILY SSF52540 27 251 7.99E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_20470 3d8f3ed07ceed1cbb816a3efba3da5c6 273 SMART SM00382 51 232 5.9E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_12625 9e6150400078ef5dd9e9d700f53005e6 323 Pfam PF01965 DJ-1/PfpI family 3 170 1.3E-13 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 LH59_12625 9e6150400078ef5dd9e9d700f53005e6 323 Gene3D G3DSA:3.40.50.880 1 205 1.7E-54 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_12625 9e6150400078ef5dd9e9d700f53005e6 323 SUPERFAMILY SSF52317 1 192 1.68E-49 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_12625 9e6150400078ef5dd9e9d700f53005e6 323 Pfam PF12833 Helix-turn-helix domain 233 312 1.3E-18 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_12625 9e6150400078ef5dd9e9d700f53005e6 323 SUPERFAMILY SSF46689 264 315 2.46E-8 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_12625 9e6150400078ef5dd9e9d700f53005e6 323 Gene3D G3DSA:1.10.10.60 210 317 2.4E-25 T 14-10-2018 LH59_12625 9e6150400078ef5dd9e9d700f53005e6 323 SMART SM00342 227 310 3.1E-20 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_12625 9e6150400078ef5dd9e9d700f53005e6 323 SUPERFAMILY SSF46689 211 261 4.31E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_24785 1494fc3dd9ed51ff66a3dcab9ac40a52 301 Gene3D G3DSA:1.10.3720.10 90 294 8.0E-17 T 14-10-2018 IPR035906 MetI-like superfamily LH59_24785 1494fc3dd9ed51ff66a3dcab9ac40a52 301 SUPERFAMILY SSF161098 91 279 1.57E-23 T 14-10-2018 IPR035906 MetI-like superfamily LH59_24785 1494fc3dd9ed51ff66a3dcab9ac40a52 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 298 2.2E-22 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_24785 1494fc3dd9ed51ff66a3dcab9ac40a52 301 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 25 66 1.5E-5 T 14-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain LH59_27455 eb8ebe7900d7cbe7740f8bfbc2179f2e 189 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 9 140 9.4E-32 T 14-10-2018 IPR010419 Carbon monoxide dehydrogenase subunit G LH59_27455 eb8ebe7900d7cbe7740f8bfbc2179f2e 189 Gene3D G3DSA:3.30.530.20 1 149 3.1E-33 T 14-10-2018 IPR023393 START-like domain superfamily LH59_27455 eb8ebe7900d7cbe7740f8bfbc2179f2e 189 SUPERFAMILY SSF55961 1 145 1.27E-30 T 14-10-2018 LH59_18135 aac6c74c8ff4592292f561f4f1b795b7 184 Pfam PF03729 Short repeat of unknown function (DUF308) 19 88 2.9E-12 T 14-10-2018 IPR005325 Protein of unknown function DUF308, membrane LH59_18135 aac6c74c8ff4592292f561f4f1b795b7 184 Pfam PF03729 Short repeat of unknown function (DUF308) 133 180 4.9E-7 T 14-10-2018 IPR005325 Protein of unknown function DUF308, membrane LH59_18135 aac6c74c8ff4592292f561f4f1b795b7 184 Pfam PF03729 Short repeat of unknown function (DUF308) 76 146 5.0E-15 T 14-10-2018 IPR005325 Protein of unknown function DUF308, membrane LH59_10530 909de0e6cbf9d54acee65b22a8e2134e 831 Gene3D G3DSA:3.40.50.740 98 626 0.0 T 14-10-2018 LH59_10530 909de0e6cbf9d54acee65b22a8e2134e 831 SUPERFAMILY SSF53706 38 705 3.8E-202 T 14-10-2018 LH59_10530 909de0e6cbf9d54acee65b22a8e2134e 831 Gene3D G3DSA:3.30.200.210 41 669 0.0 T 14-10-2018 LH59_10530 909de0e6cbf9d54acee65b22a8e2134e 831 SUPERFAMILY SSF50692 691 831 8.82E-42 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily LH59_10530 909de0e6cbf9d54acee65b22a8e2134e 831 SMART SM00926 41 95 1.8E-12 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_10530 909de0e6cbf9d54acee65b22a8e2134e 831 Pfam PF01568 Molydopterin dinucleotide binding domain 717 825 7.7E-24 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 LH59_10530 909de0e6cbf9d54acee65b22a8e2134e 831 Gene3D G3DSA:2.40.40.20 707 831 3.6E-48 T 14-10-2018 LH59_10530 909de0e6cbf9d54acee65b22a8e2134e 831 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 5 26 1.1E-4 T 14-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal LH59_10530 909de0e6cbf9d54acee65b22a8e2134e 831 Gene3D G3DSA:3.40.228.10 177 706 0.0 T 14-10-2018 LH59_10530 909de0e6cbf9d54acee65b22a8e2134e 831 TIGRFAM TIGR01706 NAPA: periplasmic nitrate reductase, large subunit 3 831 0.0 T 14-10-2018 IPR010051 Periplasmic nitrate reductase, large subunit GO:0008940|GO:0030151|GO:0042597|GO:0055114 KEGG: 00910+1.9.6.1|MetaCyc: PWY-5674 LH59_10530 909de0e6cbf9d54acee65b22a8e2134e 831 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 42 94 2.1E-15 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_10530 909de0e6cbf9d54acee65b22a8e2134e 831 Pfam PF00384 Molybdopterin oxidoreductase 98 571 4.5E-96 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_10530 909de0e6cbf9d54acee65b22a8e2134e 831 Hamap MF_01630 Periplasmic nitrate reductase [napA]. 1 831 32.396 T 14-10-2018 IPR010051 Periplasmic nitrate reductase, large subunit GO:0008940|GO:0030151|GO:0042597|GO:0055114 KEGG: 00910+1.9.6.1|MetaCyc: PWY-5674 LH59_10530 909de0e6cbf9d54acee65b22a8e2134e 831 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 46 64 - T 14-10-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 LH59_08780 b33a7a66bd17ca96eb1beeb38d800a58 605 SUPERFAMILY SSF51735 406 533 1.07E-29 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_08780 b33a7a66bd17ca96eb1beeb38d800a58 605 Gene3D G3DSA:3.40.50.720 405 561 9.8E-32 T 14-10-2018 LH59_08780 b33a7a66bd17ca96eb1beeb38d800a58 605 Pfam PF02254 TrkA-N domain 406 518 1.2E-19 T 14-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 LH59_08780 b33a7a66bd17ca96eb1beeb38d800a58 605 Gene3D G3DSA:1.20.1530.20 6 386 1.4E-80 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily LH59_08780 b33a7a66bd17ca96eb1beeb38d800a58 605 Pfam PF00999 Sodium/hydrogen exchanger family 14 377 2.5E-69 T 14-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 LH59_08780 b33a7a66bd17ca96eb1beeb38d800a58 605 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 18 288 3.2E-81 T 14-10-2018 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 LH59_28075 ae099f6dcc40739300af130fbe9e623a 333 PIRSF PIRSF017082 1 332 5.8E-81 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_28075 ae099f6dcc40739300af130fbe9e623a 333 SUPERFAMILY SSF53850 122 289 1.85E-12 T 14-10-2018 LH59_28075 ae099f6dcc40739300af130fbe9e623a 333 Gene3D G3DSA:3.40.190.150 37 323 6.1E-104 T 14-10-2018 LH59_28075 ae099f6dcc40739300af130fbe9e623a 333 Gene3D G3DSA:3.40.190.10 135 258 6.1E-104 T 14-10-2018 LH59_28075 ae099f6dcc40739300af130fbe9e623a 333 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 56 328 2.9E-76 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_28190 4003bab27e866cb6b33f37cc225c87ee 528 PIRSF PIRSF002741 20 526 3.2E-109 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 LH59_28190 4003bab27e866cb6b33f37cc225c87ee 528 Gene3D G3DSA:3.10.105.10 279 506 1.9E-136 T 14-10-2018 LH59_28190 4003bab27e866cb6b33f37cc225c87ee 528 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 71 438 5.1E-98 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain LH59_28190 4003bab27e866cb6b33f37cc225c87ee 528 SUPERFAMILY SSF53850 31 510 1.48E-133 T 14-10-2018 LH59_28190 4003bab27e866cb6b33f37cc225c87ee 528 Gene3D G3DSA:3.40.190.10 36 278 1.9E-136 T 14-10-2018 LH59_28190 4003bab27e866cb6b33f37cc225c87ee 528 Gene3D G3DSA:3.90.76.10 62 177 1.9E-136 T 14-10-2018 LH59_20085 6cd31e6d4b06aa6c89e2b7fd6c6b789d 564 SUPERFAMILY SSF56801 21 555 1.24E-149 T 14-10-2018 LH59_20085 6cd31e6d4b06aa6c89e2b7fd6c6b789d 564 Gene3D G3DSA:3.40.50.12780 12 456 8.5E-119 T 14-10-2018 LH59_20085 6cd31e6d4b06aa6c89e2b7fd6c6b789d 564 Pfam PF00501 AMP-binding enzyme 31 460 1.2E-106 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 LH59_20085 6cd31e6d4b06aa6c89e2b7fd6c6b789d 564 Gene3D G3DSA:3.30.300.310 457 556 7.3E-30 T 14-10-2018 LH59_20085 6cd31e6d4b06aa6c89e2b7fd6c6b789d 564 Pfam PF13193 AMP-binding enzyme C-terminal domain 469 543 7.5E-20 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain LH59_20085 6cd31e6d4b06aa6c89e2b7fd6c6b789d 564 ProSitePatterns PS00455 Putative AMP-binding domain signature. 210 221 - T 14-10-2018 IPR020845 AMP-binding, conserved site LH59_01855 beca649fb92773e6f08abc472c6450d9 389 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 5 386 6.2E-101 T 14-10-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 LH59_01855 beca649fb92773e6f08abc472c6450d9 389 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 293 306 - T 14-10-2018 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 LH59_01855 beca649fb92773e6f08abc472c6450d9 389 Pfam PF01494 FAD binding domain 4 338 1.5E-18 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 LH59_01855 beca649fb92773e6f08abc472c6450d9 389 Gene3D G3DSA:3.30.9.50 79 269 8.6E-80 T 14-10-2018 LH59_01855 beca649fb92773e6f08abc472c6450d9 389 SUPERFAMILY SSF51905 1 385 5.37E-48 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_01855 beca649fb92773e6f08abc472c6450d9 389 Gene3D G3DSA:3.50.50.60 5 336 8.6E-80 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_01855 beca649fb92773e6f08abc472c6450d9 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 279 294 3.8E-18 T 14-10-2018 LH59_01855 beca649fb92773e6f08abc472c6450d9 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 148 163 3.8E-18 T 14-10-2018 LH59_01855 beca649fb92773e6f08abc472c6450d9 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 3.8E-18 T 14-10-2018 LH59_01855 beca649fb92773e6f08abc472c6450d9 389 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 294 310 3.8E-18 T 14-10-2018 LH59_16145 fda3f1242a9723d076719156fc06f843 321 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 38 320 1.8E-19 T 14-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 LH59_16145 fda3f1242a9723d076719156fc06f843 321 Gene3D G3DSA:3.40.50.720 107 292 9.7E-120 T 14-10-2018 LH59_16145 fda3f1242a9723d076719156fc06f843 321 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 115 289 3.7E-56 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 LH59_16145 fda3f1242a9723d076719156fc06f843 321 SUPERFAMILY SSF52283 12 141 1.21E-29 T 14-10-2018 LH59_16145 fda3f1242a9723d076719156fc06f843 321 SUPERFAMILY SSF51735 109 289 1.51E-55 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_16145 fda3f1242a9723d076719156fc06f843 321 Gene3D G3DSA:3.40.50.720 22 314 9.7E-120 T 14-10-2018 LH59_08340 58e2e32203aa6a2280be51f2967d6d4b 393 Pfam PF04865 Baseplate J-like protein 81 328 6.2E-10 T 14-10-2018 IPR006949 Baseplate protein J-like LH59_18915 c957e1172f297f1f4ebaecdc60d000f8 567 Pfam PF16930 Putative porin 35 567 4.6E-218 T 14-10-2018 IPR032638 Putative bacterial porin LH59_18915 c957e1172f297f1f4ebaecdc60d000f8 567 SUPERFAMILY SSF56925 232 351 1.33E-7 T 14-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel LH59_20425 0568f56f81a0bf0dec6cb25a602596f4 382 Pfam PF07433 Protein of unknown function (DUF1513) 71 378 1.1E-109 T 14-10-2018 IPR008311 Uncharacterised conserved protein UCP028101 LH59_20425 0568f56f81a0bf0dec6cb25a602596f4 382 SUPERFAMILY SSF50969 63 336 7.77E-15 T 14-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like LH59_20425 0568f56f81a0bf0dec6cb25a602596f4 382 PIRSF PIRSF028101 6 380 1.4E-109 T 14-10-2018 IPR008311 Uncharacterised conserved protein UCP028101 LH59_09800 e02abce5ac4e49d19dcda38acb2200fb 368 SUPERFAMILY SSF48208 14 365 3.35E-79 T 14-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 LH59_09800 e02abce5ac4e49d19dcda38acb2200fb 368 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 42 360 1.7E-40 T 14-10-2018 LH59_09800 e02abce5ac4e49d19dcda38acb2200fb 368 Gene3D G3DSA:1.50.10.10 2 365 2.8E-62 T 14-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 LH59_27750 7d81b6d2d0ff346918888f2094018d6f 441 Hamap MF_01465 Protein translocase subunit SecY [secY]. 8 428 29.859 T 14-10-2018 IPR026593 Protein translocase subunit SecY LH59_27750 7d81b6d2d0ff346918888f2094018d6f 441 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 18 424 1.4E-136 T 14-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 LH59_27750 7d81b6d2d0ff346918888f2094018d6f 441 ProSitePatterns PS00756 Protein secY signature 2. 168 185 - T 14-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 LH59_27750 7d81b6d2d0ff346918888f2094018d6f 441 ProSitePatterns PS00755 Protein secY signature 1. 74 93 - T 14-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 LH59_27750 7d81b6d2d0ff346918888f2094018d6f 441 Gene3D G3DSA:1.10.3370.10 9 424 8.8E-168 T 14-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 LH59_27750 7d81b6d2d0ff346918888f2094018d6f 441 PIRSF PIRSF004557 9 435 2.3E-127 T 14-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 LH59_27750 7d81b6d2d0ff346918888f2094018d6f 441 SUPERFAMILY SSF103491 13 419 3.27E-135 T 14-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 LH59_27750 7d81b6d2d0ff346918888f2094018d6f 441 Pfam PF00344 SecY translocase 74 412 5.2E-119 T 14-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 LH59_27750 7d81b6d2d0ff346918888f2094018d6f 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 149 174 1.0E-96 T 14-10-2018 LH59_27750 7d81b6d2d0ff346918888f2094018d6f 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 21 39 1.0E-96 T 14-10-2018 LH59_27750 7d81b6d2d0ff346918888f2094018d6f 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 175 198 1.0E-96 T 14-10-2018 LH59_27750 7d81b6d2d0ff346918888f2094018d6f 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 114 137 1.0E-96 T 14-10-2018 LH59_27750 7d81b6d2d0ff346918888f2094018d6f 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 310 332 1.0E-96 T 14-10-2018 LH59_27750 7d81b6d2d0ff346918888f2094018d6f 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 365 383 1.0E-96 T 14-10-2018 LH59_27750 7d81b6d2d0ff346918888f2094018d6f 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 267 286 1.0E-96 T 14-10-2018 LH59_27750 7d81b6d2d0ff346918888f2094018d6f 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 397 415 1.0E-96 T 14-10-2018 LH59_27750 7d81b6d2d0ff346918888f2094018d6f 441 PRINTS PR00303 Preprotein translocase SecY subunit signature 73 93 1.0E-96 T 14-10-2018 LH59_22460 bc1698bde20f0b493ec2f42389cf3148 143 Pfam PF04828 Glutathione-dependent formaldehyde-activating enzyme 24 111 3.5E-19 T 14-10-2018 IPR006913 Glutathione-dependent formaldehyde-activating enzyme/centromere protein V GO:0016846 KEGG: 00680+4.4.1.22|MetaCyc: PWY-1801 LH59_22460 bc1698bde20f0b493ec2f42389cf3148 143 Gene3D G3DSA:2.170.150.70 2 114 1.5E-17 T 14-10-2018 LH59_22460 bc1698bde20f0b493ec2f42389cf3148 143 SUPERFAMILY SSF51316 1 133 3.35E-47 T 14-10-2018 IPR011057 Mss4-like superfamily LH59_08495 bc4e28079f835190273abe32cc6d6ddc 414 Gene3D G3DSA:3.40.640.10 5 274 3.1E-67 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_08495 bc4e28079f835190273abe32cc6d6ddc 414 PIRSF PIRSF001434 1 411 9.4E-117 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 LH59_08495 bc4e28079f835190273abe32cc6d6ddc 414 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 8 408 3.6E-104 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 LH59_08495 bc4e28079f835190273abe32cc6d6ddc 414 Gene3D G3DSA:3.90.1150.10 275 410 1.0E-41 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_08495 bc4e28079f835190273abe32cc6d6ddc 414 SUPERFAMILY SSF53383 5 409 8.29E-86 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_10605 f2c9c9c446207b06e73e9cccd8fce973 314 Gene3D G3DSA:1.10.10.10 1 87 1.7E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_10605 f2c9c9c446207b06e73e9cccd8fce973 314 SUPERFAMILY SSF46785 2 84 1.7E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_10605 f2c9c9c446207b06e73e9cccd8fce973 314 Gene3D G3DSA:3.40.190.290 92 300 2.4E-41 T 14-10-2018 LH59_10605 f2c9c9c446207b06e73e9cccd8fce973 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 59 1.1E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_10605 f2c9c9c446207b06e73e9cccd8fce973 314 SUPERFAMILY SSF53850 92 297 2.39E-41 T 14-10-2018 LH59_10605 f2c9c9c446207b06e73e9cccd8fce973 314 Pfam PF03466 LysR substrate binding domain 90 293 3.2E-42 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_10605 f2c9c9c446207b06e73e9cccd8fce973 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 5.5E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_10605 f2c9c9c446207b06e73e9cccd8fce973 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 5.5E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_10605 f2c9c9c446207b06e73e9cccd8fce973 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 5.5E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_02775 532ae28238180783097b166669dd69c3 258 Pfam PF04170 NlpE N-terminal domain 139 219 7.2E-5 T 14-10-2018 IPR007298 Copper resistance lipoprotein NlpE LH59_02775 532ae28238180783097b166669dd69c3 258 Gene3D G3DSA:2.40.128.300 119 220 6.0E-8 T 14-10-2018 LH59_12545 f5a963e15b5ee1e6d897d5edd80a0006 240 SUPERFAMILY SSF52540 3 236 3.15E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_12545 f5a963e15b5ee1e6d897d5edd80a0006 240 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 213 235 4.1E-11 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal LH59_12545 f5a963e15b5ee1e6d897d5edd80a0006 240 SMART SM00382 28 212 1.5E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_12545 f5a963e15b5ee1e6d897d5edd80a0006 240 Gene3D G3DSA:3.40.50.300 2 237 2.5E-57 T 14-10-2018 LH59_12545 f5a963e15b5ee1e6d897d5edd80a0006 240 Pfam PF00005 ABC transporter 20 163 3.1E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_11920 1f65e5deef9a97770c90613aa451117f 291 Pfam PF03466 LysR substrate binding domain 93 288 4.4E-25 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_11920 1f65e5deef9a97770c90613aa451117f 291 SUPERFAMILY SSF53850 84 289 1.99E-27 T 14-10-2018 LH59_11920 1f65e5deef9a97770c90613aa451117f 291 SUPERFAMILY SSF46785 5 114 2.77E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_11920 1f65e5deef9a97770c90613aa451117f 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 68 2.3E-16 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_11920 1f65e5deef9a97770c90613aa451117f 291 Gene3D G3DSA:3.40.190.10 165 256 6.2E-41 T 14-10-2018 LH59_11920 1f65e5deef9a97770c90613aa451117f 291 Gene3D G3DSA:1.10.10.10 8 95 9.8E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_11920 1f65e5deef9a97770c90613aa451117f 291 Gene3D G3DSA:3.40.190.10 104 284 6.2E-41 T 14-10-2018 LH59_06200 c47336fcbbf0d844aa3c5a958f28dd15 161 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 6 159 1.8E-63 T 14-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 LH59_06200 c47336fcbbf0d844aa3c5a958f28dd15 161 SUPERFAMILY SSF69765 4 160 4.71E-64 T 14-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 LH59_06200 c47336fcbbf0d844aa3c5a958f28dd15 161 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 5 160 35.52 T 14-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 LH59_06200 c47336fcbbf0d844aa3c5a958f28dd15 161 Gene3D G3DSA:3.30.1330.50 3 161 3.9E-67 T 14-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 LH59_06200 c47336fcbbf0d844aa3c5a958f28dd15 161 Pfam PF02542 YgbB family 5 158 8.3E-64 T 14-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 LH59_06200 c47336fcbbf0d844aa3c5a958f28dd15 161 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 39 54 - T 14-10-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 LH59_12460 813a006949dc95aeec5f80eff0b2ad41 548 Gene3D G3DSA:1.10.3720.10 8 278 2.1E-52 T 14-10-2018 IPR035906 MetI-like superfamily LH59_12460 813a006949dc95aeec5f80eff0b2ad41 548 SUPERFAMILY SSF161098 6 267 1.21E-45 T 14-10-2018 IPR035906 MetI-like superfamily LH59_12460 813a006949dc95aeec5f80eff0b2ad41 548 SUPERFAMILY SSF161098 289 541 2.8E-40 T 14-10-2018 IPR035906 MetI-like superfamily LH59_12460 813a006949dc95aeec5f80eff0b2ad41 548 Gene3D G3DSA:1.10.3720.10 297 542 2.7E-36 T 14-10-2018 IPR035906 MetI-like superfamily LH59_12460 813a006949dc95aeec5f80eff0b2ad41 548 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 78 271 3.2E-9 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_12460 813a006949dc95aeec5f80eff0b2ad41 548 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 360 540 2.7E-6 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_11525 96caf4980b30ad1515c15fd4cec7f2c8 336 Gene3D G3DSA:1.10.220.30 198 336 3.4E-44 T 14-10-2018 LH59_11525 96caf4980b30ad1515c15fd4cec7f2c8 336 SUPERFAMILY SSF48029 9 106 1.26E-19 T 14-10-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical LH59_11525 96caf4980b30ad1515c15fd4cec7f2c8 336 PIRSF PIRSF003161 2 336 4.5E-117 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 LH59_11525 96caf4980b30ad1515c15fd4cec7f2c8 336 Pfam PF14841 FliG middle domain 119 192 2.3E-24 T 14-10-2018 IPR032779 Flagellar motor switch protein FliG, middle domain LH59_11525 96caf4980b30ad1515c15fd4cec7f2c8 336 SUPERFAMILY SSF48029 118 328 2.09E-65 T 14-10-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical LH59_11525 96caf4980b30ad1515c15fd4cec7f2c8 336 Pfam PF14842 FliG N-terminal domain 8 104 2.2E-29 T 14-10-2018 IPR028263 Flagellar motor switch protein FliG, N-terminal domain LH59_11525 96caf4980b30ad1515c15fd4cec7f2c8 336 Pfam PF01706 FliG C-terminal domain 221 327 2.0E-40 T 14-10-2018 IPR023087 Flagellar motor switch protein FliG, C-terminal LH59_11525 96caf4980b30ad1515c15fd4cec7f2c8 336 Gene3D G3DSA:1.10.220.30 1 89 1.3E-18 T 14-10-2018 LH59_11525 96caf4980b30ad1515c15fd4cec7f2c8 336 PRINTS PR00954 Flagellar motor switch protein FliG signature 118 141 7.9E-67 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 LH59_11525 96caf4980b30ad1515c15fd4cec7f2c8 336 PRINTS PR00954 Flagellar motor switch protein FliG signature 251 271 7.9E-67 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 LH59_11525 96caf4980b30ad1515c15fd4cec7f2c8 336 PRINTS PR00954 Flagellar motor switch protein FliG signature 275 301 7.9E-67 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 LH59_11525 96caf4980b30ad1515c15fd4cec7f2c8 336 PRINTS PR00954 Flagellar motor switch protein FliG signature 8 24 7.9E-67 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 LH59_11525 96caf4980b30ad1515c15fd4cec7f2c8 336 PRINTS PR00954 Flagellar motor switch protein FliG signature 229 249 7.9E-67 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 LH59_11525 96caf4980b30ad1515c15fd4cec7f2c8 336 PRINTS PR00954 Flagellar motor switch protein FliG signature 37 63 7.9E-67 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 LH59_11525 96caf4980b30ad1515c15fd4cec7f2c8 336 PRINTS PR00954 Flagellar motor switch protein FliG signature 198 223 7.9E-67 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 LH59_11525 96caf4980b30ad1515c15fd4cec7f2c8 336 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 6 335 1.6E-119 T 14-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 LH59_11525 96caf4980b30ad1515c15fd4cec7f2c8 336 Gene3D G3DSA:1.10.220.30 93 197 2.1E-26 T 14-10-2018 LH59_05595 67ac7bb97563605d9059128e8e9e95d2 313 SUPERFAMILY SSF81345 4 310 5.49E-62 T 14-10-2018 IPR037294 ABC transporter, BtuC-like LH59_05595 67ac7bb97563605d9059128e8e9e95d2 313 Pfam PF01032 FecCD transport family 8 310 6.4E-61 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 LH59_05595 67ac7bb97563605d9059128e8e9e95d2 313 Gene3D G3DSA:1.10.3470.10 2 313 4.1E-59 T 14-10-2018 IPR037294 ABC transporter, BtuC-like LH59_01650 29591e3b3b48d3b258374712f4ceb212 409 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 31 128 4.1E-13 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 LH59_01650 29591e3b3b48d3b258374712f4ceb212 409 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 250 383 1.4E-16 T 14-10-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain LH59_01650 29591e3b3b48d3b258374712f4ceb212 409 Gene3D G3DSA:2.40.110.10 134 231 2.5E-24 T 14-10-2018 LH59_01650 29591e3b3b48d3b258374712f4ceb212 409 Gene3D G3DSA:1.20.140.10 233 409 6.7E-57 T 14-10-2018 LH59_01650 29591e3b3b48d3b258374712f4ceb212 409 SUPERFAMILY SSF56645 31 231 3.66E-39 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 LH59_01650 29591e3b3b48d3b258374712f4ceb212 409 Gene3D G3DSA:1.10.540.10 26 133 2.0E-26 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 LH59_01650 29591e3b3b48d3b258374712f4ceb212 409 PIRSF PIRSF016578 6 405 1.3E-26 T 14-10-2018 LH59_01650 29591e3b3b48d3b258374712f4ceb212 409 SUPERFAMILY SSF47203 245 400 1.1E-20 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 LH59_19920 5682de71cb0d6aa63217475f55ea9b6b 275 Hamap MF_01967 NAD-dependent protein deacetylase [cobB]. 2 272 62.013 T 14-10-2018 IPR026587 Sirtuin, class II Reactome: R-HSA-2151201 LH59_19920 5682de71cb0d6aa63217475f55ea9b6b 275 Pfam PF02146 Sir2 family 26 228 3.6E-47 T 14-10-2018 IPR003000 Sirtuin family GO:0070403 LH59_19920 5682de71cb0d6aa63217475f55ea9b6b 275 Gene3D G3DSA:3.40.50.1220 15 264 2.5E-82 T 14-10-2018 LH59_19920 5682de71cb0d6aa63217475f55ea9b6b 275 Gene3D G3DSA:3.30.1600.10 35 197 2.5E-82 T 14-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily LH59_19920 5682de71cb0d6aa63217475f55ea9b6b 275 SUPERFAMILY SSF52467 6 272 2.84E-80 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily LH59_20390 d14854f51c47907f38eb6289df399cf8 331 Gene3D G3DSA:3.10.520.20 24 328 5.4E-74 T 14-10-2018 LH59_20390 d14854f51c47907f38eb6289df399cf8 331 Pfam PF02424 ApbE family 44 310 5.2E-59 T 14-10-2018 IPR024932 Flavin transferase ApbE GO:0017013 LH59_20390 d14854f51c47907f38eb6289df399cf8 331 SUPERFAMILY SSF143631 34 322 2.09E-73 T 14-10-2018 IPR003374 ApbE-like superfamily LH59_20390 d14854f51c47907f38eb6289df399cf8 331 PIRSF PIRSF006268 4 323 5.6E-59 T 14-10-2018 IPR024932 Flavin transferase ApbE GO:0017013 LH59_02750 896d3985be76cce25849d7ff5198da8c 484 Gene3D G3DSA:1.20.1720.10 28 260 8.5E-49 T 14-10-2018 LH59_02750 896d3985be76cce25849d7ff5198da8c 484 SUPERFAMILY SSF103473 14 467 9.94E-62 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_02750 896d3985be76cce25849d7ff5198da8c 484 Pfam PF07690 Major Facilitator Superfamily 31 237 1.5E-34 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_02750 896d3985be76cce25849d7ff5198da8c 484 Pfam PF07690 Major Facilitator Superfamily 289 474 2.5E-11 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_02750 896d3985be76cce25849d7ff5198da8c 484 Gene3D G3DSA:1.20.1250.20 276 469 4.7E-18 T 14-10-2018 LH59_02750 896d3985be76cce25849d7ff5198da8c 484 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 32 433 2.2E-72 T 14-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 LH59_16735 30d081e8356a15fa0aa3fb375bef758d 249 Pfam PF01925 Sulfite exporter TauE/SafE 13 239 1.5E-26 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 LH59_00810 3d35f020f4afbb7adb96efe958e7b2a5 456 Pfam PF11067 Protein of unknown function (DUF2868) 141 434 9.2E-76 T 14-10-2018 IPR021296 Protein of unknown function DUF2868 LH59_10715 d4613b6b5e0ce590ebee0de9be213ee2 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 179 8.4E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10715 d4613b6b5e0ce590ebee0de9be213ee2 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 116 132 8.4E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10715 d4613b6b5e0ce590ebee0de9be213ee2 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 69 80 8.4E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10715 d4613b6b5e0ce590ebee0de9be213ee2 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 198 218 8.4E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10715 d4613b6b5e0ce590ebee0de9be213ee2 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 8.4E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10715 d4613b6b5e0ce590ebee0de9be213ee2 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 160 8.4E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10715 d4613b6b5e0ce590ebee0de9be213ee2 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 122 130 2.9E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10715 d4613b6b5e0ce590ebee0de9be213ee2 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 69 80 2.9E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10715 d4613b6b5e0ce590ebee0de9be213ee2 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 160 2.9E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10715 d4613b6b5e0ce590ebee0de9be213ee2 240 Gene3D G3DSA:3.40.50.720 1 238 3.6E-67 T 14-10-2018 LH59_10715 d4613b6b5e0ce590ebee0de9be213ee2 240 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 235 7.1E-46 T 14-10-2018 LH59_10715 d4613b6b5e0ce590ebee0de9be213ee2 240 SUPERFAMILY SSF51735 5 236 1.51E-63 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_25730 e8b56a1a777b7ee0d7e8191f480711e9 475 Gene3D G3DSA:3.30.70.2190 221 344 4.2E-35 T 14-10-2018 LH59_25730 e8b56a1a777b7ee0d7e8191f480711e9 475 Pfam PF02913 FAD linked oxidases, C-terminal domain 221 472 8.9E-48 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 LH59_25730 e8b56a1a777b7ee0d7e8191f480711e9 475 SUPERFAMILY SSF56176 7 221 6.82E-73 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 LH59_25730 e8b56a1a777b7ee0d7e8191f480711e9 475 Gene3D G3DSA:3.30.465.10 99 219 1.4E-45 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 LH59_25730 e8b56a1a777b7ee0d7e8191f480711e9 475 Pfam PF01565 FAD binding domain 43 181 1.8E-36 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 LH59_25730 e8b56a1a777b7ee0d7e8191f480711e9 475 SUPERFAMILY SSF55103 195 474 2.45E-51 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 LH59_25730 e8b56a1a777b7ee0d7e8191f480711e9 475 Gene3D G3DSA:1.10.45.10 434 474 5.3E-11 T 14-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 LH59_25730 e8b56a1a777b7ee0d7e8191f480711e9 475 Gene3D G3DSA:3.30.43.10 1 97 2.3E-25 T 14-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 LH59_25730 e8b56a1a777b7ee0d7e8191f480711e9 475 Gene3D G3DSA:3.30.70.2740 345 433 4.8E-21 T 14-10-2018 LH59_18215 2eea54006be9c6ff19b13e29cb5eaf9d 155 Gene3D G3DSA:3.30.530.20 1 147 6.9E-44 T 14-10-2018 IPR023393 START-like domain superfamily LH59_18215 2eea54006be9c6ff19b13e29cb5eaf9d 155 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 16 142 2.8E-30 T 14-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like LH59_18215 2eea54006be9c6ff19b13e29cb5eaf9d 155 SUPERFAMILY SSF55961 3 146 1.61E-41 T 14-10-2018 LH59_18650 0a12a55a1d504fe234a2d66029262a2e 1092 Gene3D G3DSA:3.40.50.300 516 654 9.3E-11 T 14-10-2018 LH59_18650 0a12a55a1d504fe234a2d66029262a2e 1092 Pfam PF01935 Domain of unknown function DUF87 561 780 2.3E-10 T 14-10-2018 IPR002789 Helicase HerA, central domain LH59_18650 0a12a55a1d504fe234a2d66029262a2e 1092 Gene3D G3DSA:3.40.50.300 711 932 1.5E-34 T 14-10-2018 LH59_18650 0a12a55a1d504fe234a2d66029262a2e 1092 SUPERFAMILY SSF52540 560 929 8.54E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_19365 760100f1ff17718191d77c2fdffd9b3c 251 SUPERFAMILY SSF56219 3 249 1.57E-44 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily LH59_19365 760100f1ff17718191d77c2fdffd9b3c 251 Gene3D G3DSA:3.60.10.10 4 251 5.1E-38 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily LH59_19365 760100f1ff17718191d77c2fdffd9b3c 251 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 29 242 2.2E-16 T 14-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase LH59_21895 ce68e5fb6d8904d2e7f56944517efe82 691 SUPERFAMILY SSF143724 114 319 9.22E-62 T 14-10-2018 LH59_21895 ce68e5fb6d8904d2e7f56944517efe82 691 Hamap MF_00347 Polyphosphate kinase [ppk]. 8 691 27.541 T 14-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 LH59_21895 ce68e5fb6d8904d2e7f56944517efe82 691 Pfam PF13089 Polyphosphate kinase N-terminal domain 12 116 1.5E-33 T 14-10-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 LH59_21895 ce68e5fb6d8904d2e7f56944517efe82 691 SUPERFAMILY SSF140356 9 112 7.98E-34 T 14-10-2018 IPR036832 Polyphosphate kinase N-terminal domain superfamily KEGG: 00190+2.7.4.1 LH59_21895 ce68e5fb6d8904d2e7f56944517efe82 691 Gene3D G3DSA:3.30.870.10 331 509 1.1E-71 T 14-10-2018 LH59_21895 ce68e5fb6d8904d2e7f56944517efe82 691 PIRSF PIRSF015589 3 690 5.8E-263 T 14-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 LH59_21895 ce68e5fb6d8904d2e7f56944517efe82 691 SUPERFAMILY SSF56024 511 687 6.73E-69 T 14-10-2018 LH59_21895 ce68e5fb6d8904d2e7f56944517efe82 691 Pfam PF13090 Polyphosphate kinase C-terminal domain 340 687 3.8E-154 T 14-10-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 LH59_21895 ce68e5fb6d8904d2e7f56944517efe82 691 Gene3D G3DSA:3.30.1840.10 7 317 1.1E-96 T 14-10-2018 IPR036830 Polyphosphate kinase middle domain superfamily KEGG: 00190+2.7.4.1 LH59_21895 ce68e5fb6d8904d2e7f56944517efe82 691 Pfam PF02503 Polyphosphate kinase middle domain 125 324 1.0E-57 T 14-10-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 LH59_21895 ce68e5fb6d8904d2e7f56944517efe82 691 SUPERFAMILY SSF56024 336 502 2.01E-55 T 14-10-2018 LH59_21895 ce68e5fb6d8904d2e7f56944517efe82 691 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 11 687 2.1E-288 T 14-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 LH59_21895 ce68e5fb6d8904d2e7f56944517efe82 691 Gene3D G3DSA:3.30.870.10 510 689 9.4E-66 T 14-10-2018 LH59_07275 fe1d2163d1059f7250d699db18e4fd84 373 Pfam PF00155 Aminotransferase class I and II 40 361 9.6E-51 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LH59_07275 fe1d2163d1059f7250d699db18e4fd84 373 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 232 241 - T 14-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 LH59_07275 fe1d2163d1059f7250d699db18e4fd84 373 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 9 371 60.686 T 14-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 LH59_07275 fe1d2163d1059f7250d699db18e4fd84 373 Gene3D G3DSA:3.90.1150.10 18 364 9.3E-111 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_07275 fe1d2163d1059f7250d699db18e4fd84 373 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 13 369 3.9E-103 T 14-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 LH59_07275 fe1d2163d1059f7250d699db18e4fd84 373 SUPERFAMILY SSF53383 19 370 5.7E-81 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_07275 fe1d2163d1059f7250d699db18e4fd84 373 Gene3D G3DSA:3.40.640.10 52 280 9.3E-111 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_25715 44dc7c5562bab04d2a7b87dad0881f17 481 Pfam PF07690 Major Facilitator Superfamily 29 428 1.8E-41 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_25715 44dc7c5562bab04d2a7b87dad0881f17 481 SUPERFAMILY SSF103473 214 479 4.84E-22 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_25715 44dc7c5562bab04d2a7b87dad0881f17 481 SUPERFAMILY SSF103473 22 207 1.96E-39 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_25715 44dc7c5562bab04d2a7b87dad0881f17 481 PRINTS PR01036 Tetracycline resistance protein TetB signature 118 138 5.1E-6 T 14-10-2018 LH59_25715 44dc7c5562bab04d2a7b87dad0881f17 481 PRINTS PR01036 Tetracycline resistance protein TetB signature 148 172 5.1E-6 T 14-10-2018 LH59_25715 44dc7c5562bab04d2a7b87dad0881f17 481 PRINTS PR01036 Tetracycline resistance protein TetB signature 27 51 5.1E-6 T 14-10-2018 LH59_25715 44dc7c5562bab04d2a7b87dad0881f17 481 Gene3D G3DSA:1.20.1250.20 275 481 1.4E-14 T 14-10-2018 LH59_25715 44dc7c5562bab04d2a7b87dad0881f17 481 Gene3D G3DSA:1.20.1720.10 25 232 6.5E-42 T 14-10-2018 LH59_08920 2540968ff522e64725372f2319de3fae 326 Pfam PF00892 EamA-like transporter family 19 158 4.8E-14 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_08920 2540968ff522e64725372f2319de3fae 326 Pfam PF00892 EamA-like transporter family 172 307 8.3E-17 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_08920 2540968ff522e64725372f2319de3fae 326 SUPERFAMILY SSF103481 53 161 3.27E-14 T 14-10-2018 LH59_08920 2540968ff522e64725372f2319de3fae 326 SUPERFAMILY SSF103481 226 310 1.26E-10 T 14-10-2018 LH59_07345 ea814f44b55a6555e5f37eec922b8464 349 SUPERFAMILY SSF102198 97 348 2.09E-11 T 14-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 LH59_07345 ea814f44b55a6555e5f37eec922b8464 349 Gene3D G3DSA:3.50.30.50 163 348 3.6E-10 T 14-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 LH59_07345 ea814f44b55a6555e5f37eec922b8464 349 Pfam PF04199 Putative cyclase 88 277 8.2E-14 T 14-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 LH59_01505 396edf1c37273d80dc140fd7b809a3f8 567 SUPERFAMILY SSF103473 39 422 1.27E-47 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_01505 396edf1c37273d80dc140fd7b809a3f8 567 Gene3D G3DSA:1.20.1250.20 38 422 9.0E-38 T 14-10-2018 LH59_01505 396edf1c37273d80dc140fd7b809a3f8 567 Pfam PF05977 Transmembrane secretion effector 30 547 9.2E-190 T 14-10-2018 IPR010290 Transmembrane secretion effector LH59_18325 4fe16f0a5429beba339be03ca47dfbff 227 SUPERFAMILY SSF89562 26 182 8.63E-47 T 14-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily LH59_18325 4fe16f0a5429beba339be03ca47dfbff 227 Pfam PF03737 Aldolase/RraA 29 174 3.5E-44 T 14-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein LH59_18325 4fe16f0a5429beba339be03ca47dfbff 227 Gene3D G3DSA:3.50.30.100 2 196 3.5E-57 T 14-10-2018 LH59_23340 86a5d729cbc9411095ea99a2802698b9 658 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 56 503 5.1E-138 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_23340 86a5d729cbc9411095ea99a2802698b9 658 Gene3D G3DSA:1.20.210.10 31 564 3.6E-194 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_23340 86a5d729cbc9411095ea99a2802698b9 658 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 280 334 - T 14-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_23340 86a5d729cbc9411095ea99a2802698b9 658 SUPERFAMILY SSF81442 43 558 4.32E-179 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_23340 86a5d729cbc9411095ea99a2802698b9 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 324 339 7.1E-98 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_23340 86a5d729cbc9411095ea99a2802698b9 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 461 482 7.1E-98 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_23340 86a5d729cbc9411095ea99a2802698b9 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 278 299 7.1E-98 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_23340 86a5d729cbc9411095ea99a2802698b9 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 411 430 7.1E-98 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_23340 86a5d729cbc9411095ea99a2802698b9 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 124 148 7.1E-98 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_23340 86a5d729cbc9411095ea99a2802698b9 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 227 246 7.1E-98 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_23340 86a5d729cbc9411095ea99a2802698b9 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 166 178 7.1E-98 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_23340 86a5d729cbc9411095ea99a2802698b9 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 383 401 7.1E-98 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_23340 86a5d729cbc9411095ea99a2802698b9 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 47 72 7.1E-98 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_23340 86a5d729cbc9411095ea99a2802698b9 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 97 120 7.1E-98 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_23340 86a5d729cbc9411095ea99a2802698b9 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 198 216 7.1E-98 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_23340 86a5d729cbc9411095ea99a2802698b9 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 348 369 7.1E-98 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_23340 86a5d729cbc9411095ea99a2802698b9 658 TIGRFAM TIGR02843 CyoB: cytochrome o ubiquinol oxidase, subunit I 2 647 0.0 T 14-10-2018 IPR014207 Cytochrome o ubiquinol oxidase, subunit I GO:0016682|GO:0055114 MetaCyc: PWY-7544 LH59_27895 f9b48ac1ce508ea59c421d44fb0457aa 275 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 117 9.1E-33 T 14-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_27895 f9b48ac1ce508ea59c421d44fb0457aa 275 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 4 273 8.0E-128 T 14-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 LH59_27895 f9b48ac1ce508ea59c421d44fb0457aa 275 SUPERFAMILY SSF50249 3 124 2.16E-46 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_27895 f9b48ac1ce508ea59c421d44fb0457aa 275 SMART SM01382 124 252 2.1E-87 T 14-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 LH59_27895 f9b48ac1ce508ea59c421d44fb0457aa 275 Gene3D G3DSA:4.10.950.10 197 274 3.4E-35 T 14-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27895 f9b48ac1ce508ea59c421d44fb0457aa 275 PIRSF PIRSF002158 6 275 4.1E-101 T 14-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_27895 f9b48ac1ce508ea59c421d44fb0457aa 275 SMART SM01383 42 118 1.8E-42 T 14-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_27895 f9b48ac1ce508ea59c421d44fb0457aa 275 SUPERFAMILY SSF50104 127 272 1.62E-60 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily LH59_27895 f9b48ac1ce508ea59c421d44fb0457aa 275 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 126 250 1.2E-55 T 14-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 LH59_27895 f9b48ac1ce508ea59c421d44fb0457aa 275 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 273 46.167 T 14-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 LH59_27895 f9b48ac1ce508ea59c421d44fb0457aa 275 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 14-10-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27895 f9b48ac1ce508ea59c421d44fb0457aa 275 Gene3D G3DSA:2.30.30.30 118 196 1.2E-31 T 14-10-2018 IPR014722 Ribosomal protein L2, domain 2 LH59_27895 f9b48ac1ce508ea59c421d44fb0457aa 275 Gene3D G3DSA:2.40.50.140 1 114 3.0E-46 T 14-10-2018 LH59_09250 9d711050e03cb2d5ba7d68feaf454881 380 Pfam PF00534 Glycosyl transferases group 1 175 344 1.9E-29 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 LH59_09250 9d711050e03cb2d5ba7d68feaf454881 380 Gene3D G3DSA:3.40.50.2000 1 168 1.0E-12 T 14-10-2018 LH59_09250 9d711050e03cb2d5ba7d68feaf454881 380 SUPERFAMILY SSF53756 3 363 9.42E-65 T 14-10-2018 LH59_09250 9d711050e03cb2d5ba7d68feaf454881 380 Gene3D G3DSA:3.40.50.2000 169 348 4.7E-44 T 14-10-2018 LH59_09250 9d711050e03cb2d5ba7d68feaf454881 380 Pfam PF13439 Glycosyltransferase Family 4 13 155 3.5E-14 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 LH59_05040 14cfaad23ddf477718b21e3440bb8eea 341 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 94 112 - T 14-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 LH59_05040 14cfaad23ddf477718b21e3440bb8eea 341 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 3 317 5.5E-116 T 14-10-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 LH59_05040 14cfaad23ddf477718b21e3440bb8eea 341 Gene3D G3DSA:3.20.20.70 7 252 2.7E-75 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_05040 14cfaad23ddf477718b21e3440bb8eea 341 Pfam PF01207 Dihydrouridine synthase (Dus) 14 312 4.1E-99 T 14-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 LH59_05040 14cfaad23ddf477718b21e3440bb8eea 341 PIRSF PIRSF006621 1 323 3.1E-100 T 14-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 LH59_05040 14cfaad23ddf477718b21e3440bb8eea 341 SUPERFAMILY SSF51395 10 316 2.23E-86 T 14-10-2018 LH59_05040 14cfaad23ddf477718b21e3440bb8eea 341 Gene3D G3DSA:1.10.1200.80 255 323 3.9E-10 T 14-10-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 LH59_05040 14cfaad23ddf477718b21e3440bb8eea 341 Hamap MF_02042 tRNA-dihydrouridine synthase B [dusB]. 1 324 49.31 T 14-10-2018 IPR032887 tRNA-dihydrouridine synthase B GO:0002943|GO:0017150 LH59_20050 e886a9c2e6fb1e671f06502804b5105d 429 Pfam PF02803 Thiolase, C-terminal domain 288 424 1.5E-39 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 LH59_20050 e886a9c2e6fb1e671f06502804b5105d 429 Pfam PF00108 Thiolase, N-terminal domain 6 280 1.6E-56 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 LH59_20050 e886a9c2e6fb1e671f06502804b5105d 429 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 8 424 5.2E-125 T 14-10-2018 IPR002155 Thiolase GO:0016747 LH59_20050 e886a9c2e6fb1e671f06502804b5105d 429 SUPERFAMILY SSF53901 6 287 6.01E-61 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_20050 e886a9c2e6fb1e671f06502804b5105d 429 SUPERFAMILY SSF53901 288 424 4.34E-37 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_20050 e886a9c2e6fb1e671f06502804b5105d 429 Gene3D G3DSA:3.40.47.10 8 293 1.8E-122 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_20050 e886a9c2e6fb1e671f06502804b5105d 429 ProSitePatterns PS00737 Thiolases signature 2. 372 388 - T 14-10-2018 IPR020613 Thiolase, conserved site GO:0016747 LH59_20050 e886a9c2e6fb1e671f06502804b5105d 429 ProSitePatterns PS00099 Thiolases active site. 407 420 - T 14-10-2018 IPR020610 Thiolase, active site GO:0016747 LH59_20050 e886a9c2e6fb1e671f06502804b5105d 429 PIRSF PIRSF000429 1 427 6.4E-129 T 14-10-2018 IPR002155 Thiolase GO:0016747 LH59_20050 e886a9c2e6fb1e671f06502804b5105d 429 Gene3D G3DSA:3.40.47.10 128 424 1.8E-122 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_03530 9754896d5269f364695dc97ad56b0d5c 143 Pfam PF13581 Histidine kinase-like ATPase domain 13 139 5.8E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_03530 9754896d5269f364695dc97ad56b0d5c 143 Gene3D G3DSA:3.30.565.10 2 143 9.9E-19 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_03530 9754896d5269f364695dc97ad56b0d5c 143 SUPERFAMILY SSF55874 39 130 4.24E-8 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_17135 6ad491414f9b45480f83bb915587d5f1 345 Pfam PF02653 Branched-chain amino acid transport system / permease component 51 320 2.1E-33 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_09130 7a05d0fd88f74427908201986877279c 217 SUPERFAMILY SSF161098 13 206 7.06E-45 T 14-10-2018 IPR035906 MetI-like superfamily LH59_09130 7a05d0fd88f74427908201986877279c 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 213 5.8E-22 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_09130 7a05d0fd88f74427908201986877279c 217 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 109 1.8E-28 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 LH59_09130 7a05d0fd88f74427908201986877279c 217 Gene3D G3DSA:1.10.3720.10 3 216 3.6E-53 T 14-10-2018 IPR035906 MetI-like superfamily LH59_13760 7b8b6ba4fccabe0bd260470449bac39f 566 Gene3D G3DSA:3.50.50.60 43 297 2.0E-10 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_13760 7b8b6ba4fccabe0bd260470449bac39f 566 SUPERFAMILY SSF51905 28 362 6.48E-26 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_13760 7b8b6ba4fccabe0bd260470449bac39f 566 TIGRFAM TIGR01320 mal_quin_oxido: malate dehydrogenase (acceptor) 42 524 1.9E-198 T 14-10-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 LH59_13760 7b8b6ba4fccabe0bd260470449bac39f 566 Hamap MF_00212 Probable malate:quinone oxidoreductase [mqo]. 37 526 52.22 T 14-10-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 LH59_13760 7b8b6ba4fccabe0bd260470449bac39f 566 Pfam PF06039 Malate:quinone oxidoreductase (Mqo) 41 526 1.2E-219 T 14-10-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 LH59_13760 7b8b6ba4fccabe0bd260470449bac39f 566 Gene3D G3DSA:3.30.9.10 146 309 2.0E-10 T 14-10-2018 LH59_18715 e2342855aae2ae8e04d78d981b9a5a81 167 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 20 134 3.3E-11 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain LH59_18715 e2342855aae2ae8e04d78d981b9a5a81 167 SUPERFAMILY SSF54593 12 137 9.53E-37 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_18715 e2342855aae2ae8e04d78d981b9a5a81 167 Gene3D G3DSA:3.10.180.10 14 148 1.7E-39 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_06505 5e62e0f23c4487e571dbd1321c307568 250 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 11 192 2.3E-4 T 14-10-2018 LH59_06505 5e62e0f23c4487e571dbd1321c307568 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 247 1.0E-67 T 14-10-2018 LH59_06505 5e62e0f23c4487e571dbd1321c307568 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 1.4E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_06505 5e62e0f23c4487e571dbd1321c307568 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 1.4E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_06505 5e62e0f23c4487e571dbd1321c307568 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 1.4E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_06505 5e62e0f23c4487e571dbd1321c307568 250 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 13 248 3.6E-98 T 14-10-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 LH59_06505 5e62e0f23c4487e571dbd1321c307568 250 Gene3D G3DSA:3.40.50.720 5 250 2.8E-85 T 14-10-2018 LH59_06505 5e62e0f23c4487e571dbd1321c307568 250 SUPERFAMILY SSF51735 9 249 1.75E-84 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_06505 5e62e0f23c4487e571dbd1321c307568 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 2.5E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_06505 5e62e0f23c4487e571dbd1321c307568 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 2.5E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_06505 5e62e0f23c4487e571dbd1321c307568 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 2.5E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_06505 5e62e0f23c4487e571dbd1321c307568 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 2.5E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_06505 5e62e0f23c4487e571dbd1321c307568 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 2.5E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_06505 5e62e0f23c4487e571dbd1321c307568 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 2.5E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_06505 5e62e0f23c4487e571dbd1321c307568 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LH59_15270 66fff5e0b6a258d6239475102c136a4f 429 Pfam PF08281 Sigma-70, region 4 129 178 1.6E-9 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LH59_15270 66fff5e0b6a258d6239475102c136a4f 429 SUPERFAMILY SSF88659 118 179 9.81E-11 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like LH59_15270 66fff5e0b6a258d6239475102c136a4f 429 Gene3D G3DSA:1.10.1740.10 2 80 6.0E-7 T 14-10-2018 LH59_15270 66fff5e0b6a258d6239475102c136a4f 429 SUPERFAMILY SSF88946 11 80 1.73E-11 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 LH59_15270 66fff5e0b6a258d6239475102c136a4f 429 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 31 178 1.5E-12 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 LH59_15270 66fff5e0b6a258d6239475102c136a4f 429 Pfam PF04542 Sigma-70 region 2 29 80 4.1E-8 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 LH59_15270 66fff5e0b6a258d6239475102c136a4f 429 Gene3D G3DSA:1.10.10.10 129 182 1.1E-6 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_02415 20e351b46e70665cd989b89db342eb3a 333 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 26 296 1.8E-86 T 14-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B LH59_02415 20e351b46e70665cd989b89db342eb3a 333 SMART SM00797 24 313 1.1E-123 T 14-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B LH59_02415 20e351b46e70665cd989b89db342eb3a 333 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 3 319 1.2E-89 T 14-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B LH59_02415 20e351b46e70665cd989b89db342eb3a 333 Gene3D G3DSA:2.40.100.10 186 322 6.4E-48 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily LH59_02415 20e351b46e70665cd989b89db342eb3a 333 SUPERFAMILY SSF50891 196 303 9.86E-8 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily LH59_04400 bb9684ed8ad8c3ad85fa18090f725240 757 Gene3D G3DSA:1.20.140.10 528 628 5.8E-5 T 14-10-2018 LH59_04400 bb9684ed8ad8c3ad85fa18090f725240 757 SUPERFAMILY SSF56645 63 299 3.8E-48 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 LH59_04400 bb9684ed8ad8c3ad85fa18090f725240 757 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 82 175 1.7E-14 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 LH59_04400 bb9684ed8ad8c3ad85fa18090f725240 757 SUPERFAMILY SSF47203 304 451 6.28E-23 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 LH59_04400 bb9684ed8ad8c3ad85fa18090f725240 757 Pfam PF09317 Domain of unknown function (DUF1974) 458 734 2.1E-85 T 14-10-2018 IPR015396 Acyl-CoA dehydrogenase, C-termina, bacterial type GO:0003995|GO:0033539|GO:0055114 KEGG: 00071+1.3.8.8+1.3.8.7|KEGG: 00280+1.3.8.7|KEGG: 00410+1.3.8.7|KEGG: 00640+1.3.8.7|MetaCyc: PWY-7094|MetaCyc: PWY-7654 LH59_04400 bb9684ed8ad8c3ad85fa18090f725240 757 Gene3D G3DSA:2.40.110.10 179 303 5.1E-91 T 14-10-2018 LH59_04400 bb9684ed8ad8c3ad85fa18090f725240 757 Gene3D G3DSA:1.10.540.10 65 178 5.1E-91 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 LH59_04400 bb9684ed8ad8c3ad85fa18090f725240 757 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 304 451 3.9E-13 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LH59_04400 bb9684ed8ad8c3ad85fa18090f725240 757 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 180 272 1.5E-10 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 LH59_04400 bb9684ed8ad8c3ad85fa18090f725240 757 Gene3D G3DSA:1.20.140.10 304 451 5.1E-91 T 14-10-2018 LH59_09605 ddbf81a280046948dab1b7d7c1ae11f9 304 SUPERFAMILY SSF51735 4 296 1.4E-88 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_09605 ddbf81a280046948dab1b7d7c1ae11f9 304 Pfam PF04321 RmlD substrate binding domain 4 297 2.0E-97 T 14-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 LH59_09605 ddbf81a280046948dab1b7d7c1ae11f9 304 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 4 296 1.7E-90 T 14-10-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 LH59_09605 ddbf81a280046948dab1b7d7c1ae11f9 304 Gene3D G3DSA:3.40.50.720 5 284 5.7E-99 T 14-10-2018 LH59_09605 ddbf81a280046948dab1b7d7c1ae11f9 304 Gene3D G3DSA:3.90.25.10 160 290 5.7E-99 T 14-10-2018 LH59_01450 c067e25673fb7e67b596a323b10d95f1 563 Hamap MF_00577 Urocanate hydratase [hutU]. 1 560 50.753 T 14-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 LH59_01450 c067e25673fb7e67b596a323b10d95f1 563 SUPERFAMILY SSF111326 11 560 1.26E-262 T 14-10-2018 IPR036190 Urocanase superfamily KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 LH59_01450 c067e25673fb7e67b596a323b10d95f1 563 PIRSF PIRSF001423 1 563 2.0E-296 T 14-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 LH59_01450 c067e25673fb7e67b596a323b10d95f1 563 TIGRFAM TIGR01228 hutU: urocanate hydratase 15 558 0.0 T 14-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 LH59_01450 c067e25673fb7e67b596a323b10d95f1 563 Pfam PF01175 Urocanase Rossmann-like domain 145 353 2.0E-86 T 14-10-2018 IPR035085 Urocanase, Rossmann-like domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 LH59_01450 c067e25673fb7e67b596a323b10d95f1 563 ProSitePatterns PS01233 Urocanase signature. 446 461 - T 14-10-2018 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 LH59_01450 c067e25673fb7e67b596a323b10d95f1 563 Pfam PF17391 Urocanase N-terminal domain 16 142 2.8E-62 T 14-10-2018 IPR035400 Urocanase, N-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 LH59_01450 c067e25673fb7e67b596a323b10d95f1 563 Gene3D G3DSA:3.40.50.10730 146 353 3.0E-263 T 14-10-2018 IPR038364 Urocanase, central domain superfamily KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 LH59_01450 c067e25673fb7e67b596a323b10d95f1 563 Gene3D G3DSA:3.40.1770.10 21 546 3.0E-263 T 14-10-2018 LH59_01450 c067e25673fb7e67b596a323b10d95f1 563 Pfam PF17392 Urocanase C-terminal domain 356 550 1.1E-92 T 14-10-2018 IPR035401 Urocanase, C-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 LH59_11955 64704d5d318174855b1a24162c8b29c0 179 Pfam PF00578 AhpC/TSA family 25 153 3.5E-25 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 LH59_11955 64704d5d318174855b1a24162c8b29c0 179 Gene3D G3DSA:3.40.30.10 18 177 6.2E-35 T 14-10-2018 LH59_11955 64704d5d318174855b1a24162c8b29c0 179 SUPERFAMILY SSF52833 21 174 5.7E-41 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_11955 64704d5d318174855b1a24162c8b29c0 179 PIRSF PIRSF000239 19 179 5.3E-20 T 14-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 LH59_21180 2fb3e59ac2767f8e39d95c96105a72a0 428 Gene3D G3DSA:1.20.1250.20 10 197 4.2E-26 T 14-10-2018 LH59_21180 2fb3e59ac2767f8e39d95c96105a72a0 428 Pfam PF07690 Major Facilitator Superfamily 35 293 1.2E-27 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_21180 2fb3e59ac2767f8e39d95c96105a72a0 428 SUPERFAMILY SSF103473 12 412 2.49E-55 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_21180 2fb3e59ac2767f8e39d95c96105a72a0 428 Gene3D G3DSA:1.20.1250.20 225 418 1.1E-18 T 14-10-2018 LH59_01375 c960fe51bf03131a682453657d224249 343 Gene3D G3DSA:3.90.550.10 8 213 3.3E-39 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases LH59_01375 c960fe51bf03131a682453657d224249 343 SUPERFAMILY SSF53448 20 250 7.31E-41 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases LH59_01375 c960fe51bf03131a682453657d224249 343 Pfam PF00535 Glycosyl transferase family 2 21 183 8.7E-34 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 LH59_11925 3414285bb5c8309bbbba6beca973466a 383 Gene3D G3DSA:3.40.980.20 275 380 8.5E-15 T 14-10-2018 LH59_11925 3414285bb5c8309bbbba6beca973466a 383 Pfam PF07005 Putative sugar-binding N-terminal domain 11 221 4.2E-37 T 14-10-2018 IPR010737 Four-carbon acid sugar kinase, N-terminal domain LH59_11925 3414285bb5c8309bbbba6beca973466a 383 Gene3D G3DSA:3.40.50.10840 10 229 5.3E-42 T 14-10-2018 IPR037051 Four-carbon acid sugar kinase, N-terminal domain superfamily LH59_11925 3414285bb5c8309bbbba6beca973466a 383 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 290 373 2.8E-12 T 14-10-2018 IPR031475 Four-carbon acid sugar kinase, C-terminal domain LH59_11925 3414285bb5c8309bbbba6beca973466a 383 SUPERFAMILY SSF142764 11 380 2.35E-68 T 14-10-2018 LH59_02225 35e7ccd4c2349857e0c658e8541d2da1 143 Pfam PF07883 Cupin domain 59 129 1.6E-16 T 14-10-2018 IPR013096 Cupin 2, conserved barrel LH59_02225 35e7ccd4c2349857e0c658e8541d2da1 143 Gene3D G3DSA:2.60.120.10 24 138 1.7E-18 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_02225 35e7ccd4c2349857e0c658e8541d2da1 143 SUPERFAMILY SSF51182 38 131 1.86E-22 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_17950 d01c5ab1a758feeb0097a6426c18a520 349 TIGRFAM TIGR00682 lpxK: tetraacyldisaccharide 4'-kinase 35 331 7.2E-70 T 14-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 LH59_17950 d01c5ab1a758feeb0097a6426c18a520 349 Pfam PF02606 Tetraacyldisaccharide-1-P 4'-kinase 22 341 2.0E-100 T 14-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 LH59_17950 d01c5ab1a758feeb0097a6426c18a520 349 SUPERFAMILY SSF52540 55 195 5.97E-9 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_17950 d01c5ab1a758feeb0097a6426c18a520 349 Hamap MF_00409 Tetraacyldisaccharide 4'-kinase [lpxK]. 10 346 38.391 T 14-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 LH59_26845 9e937aad40661a04cb4eee2389b72f22 153 Pfam PF01047 MarR family 44 102 8.2E-17 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_26845 9e937aad40661a04cb4eee2389b72f22 153 SMART SM00347 37 136 4.4E-26 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_26845 9e937aad40661a04cb4eee2389b72f22 153 Gene3D G3DSA:1.10.10.10 9 150 2.8E-38 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_26845 9e937aad40661a04cb4eee2389b72f22 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 97 113 3.3E-6 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_26845 9e937aad40661a04cb4eee2389b72f22 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 78 93 3.3E-6 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_26845 9e937aad40661a04cb4eee2389b72f22 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 61 77 3.3E-6 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_26845 9e937aad40661a04cb4eee2389b72f22 153 SUPERFAMILY SSF46785 10 149 1.01E-35 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_03520 66bedbeec8b349bccb89efcf1bba444a 815 Gene3D G3DSA:1.20.1250.20 624 814 2.7E-17 T 14-10-2018 LH59_03520 66bedbeec8b349bccb89efcf1bba444a 815 SUPERFAMILY SSF103473 422 811 3.27E-40 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_03520 66bedbeec8b349bccb89efcf1bba444a 815 Gene3D G3DSA:1.20.1250.20 417 615 7.1E-13 T 14-10-2018 LH59_03520 66bedbeec8b349bccb89efcf1bba444a 815 Pfam PF07690 Major Facilitator Superfamily 463 749 1.5E-24 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_22755 ada90379bef4da7122db0908883c97f3 103 Gene3D G3DSA:1.10.260.40 6 92 4.8E-21 T 14-10-2018 LH59_22755 ada90379bef4da7122db0908883c97f3 103 Pfam PF13744 Helix-turn-helix domain 10 89 3.3E-27 T 14-10-2018 IPR039554 HigA2-like, helix-turn-helix domain LH59_22755 ada90379bef4da7122db0908883c97f3 103 SUPERFAMILY SSF47413 18 92 4.5E-20 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 LH59_22755 ada90379bef4da7122db0908883c97f3 103 SMART SM00530 31 87 0.0029 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LH59_15190 71a872843b8331737c745fbb9a606863 201 SUPERFAMILY SSF48498 96 199 2.25E-9 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily LH59_15190 71a872843b8331737c745fbb9a606863 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 9.5E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_15190 71a872843b8331737c745fbb9a606863 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 9.5E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_15190 71a872843b8331737c745fbb9a606863 201 Gene3D G3DSA:1.10.357.10 68 201 1.2E-15 T 14-10-2018 LH59_15190 71a872843b8331737c745fbb9a606863 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 66 5.3E-13 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_15190 71a872843b8331737c745fbb9a606863 201 SUPERFAMILY SSF46689 13 86 7.18E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_15190 71a872843b8331737c745fbb9a606863 201 Gene3D G3DSA:1.10.10.60 12 67 2.8E-16 T 14-10-2018 LH59_24080 e91552940f9790988ee5781fea532c1e 334 Gene3D G3DSA:3.60.15.10 11 164 1.7E-16 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like LH59_24080 e91552940f9790988ee5781fea532c1e 334 TIGRFAM TIGR04122 Xnuc_lig_assoc: putative exonuclease, DNA ligase-associated 5 333 2.6E-141 T 14-10-2018 IPR026360 Putative exonuclease, DNA ligase-associated LH59_24080 e91552940f9790988ee5781fea532c1e 334 SUPERFAMILY SSF56281 11 327 1.44E-58 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like LH59_03165 4efcccb9cdd6ab0fba30930435a24488 176 Pfam PF08534 Redoxin 36 163 4.6E-17 T 14-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 LH59_03165 4efcccb9cdd6ab0fba30930435a24488 176 SUPERFAMILY SSF52833 1 171 3.31E-33 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_03165 4efcccb9cdd6ab0fba30930435a24488 176 ProSitePatterns PS00194 Thioredoxin family active site. 67 85 - T 14-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 LH59_03165 4efcccb9cdd6ab0fba30930435a24488 176 Gene3D G3DSA:3.40.30.10 45 175 5.0E-34 T 14-10-2018 LH59_16170 948d9f13c2e2db0597b5bb088d6c835d 311 Gene3D G3DSA:3.40.190.290 95 304 2.7E-37 T 14-10-2018 LH59_16170 948d9f13c2e2db0597b5bb088d6c835d 311 SUPERFAMILY SSF53850 95 301 2.17E-37 T 14-10-2018 LH59_16170 948d9f13c2e2db0597b5bb088d6c835d 311 Gene3D G3DSA:1.10.10.10 6 88 3.7E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_16170 948d9f13c2e2db0597b5bb088d6c835d 311 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 67 1.3E-19 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_16170 948d9f13c2e2db0597b5bb088d6c835d 311 Pfam PF03466 LysR substrate binding domain 93 299 5.8E-38 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_16170 948d9f13c2e2db0597b5bb088d6c835d 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.6E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_16170 948d9f13c2e2db0597b5bb088d6c835d 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.6E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_16170 948d9f13c2e2db0597b5bb088d6c835d 311 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.6E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_16170 948d9f13c2e2db0597b5bb088d6c835d 311 SUPERFAMILY SSF46785 11 116 2.73E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_26300 8af858784e18f33b80d5beb068b6d805 103 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 2.1E-36 T 14-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_26300 8af858784e18f33b80d5beb068b6d805 103 ProSitePatterns PS01169 Ribosomal protein L21 signature. 72 94 - T 14-10-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_26300 8af858784e18f33b80d5beb068b6d805 103 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 101 1.9E-39 T 14-10-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_26300 8af858784e18f33b80d5beb068b6d805 103 SUPERFAMILY SSF141091 1 101 1.7E-37 T 14-10-2018 IPR036164 L21-like superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_26300 8af858784e18f33b80d5beb068b6d805 103 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 103 27.045 T 14-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_10570 12f5de83895a1cc657035e6dc045dd35 331 SUPERFAMILY SSF53850 95 290 3.86E-14 T 14-10-2018 LH59_10570 12f5de83895a1cc657035e6dc045dd35 331 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 327 7.4E-88 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_10570 12f5de83895a1cc657035e6dc045dd35 331 Gene3D G3DSA:3.40.190.150 34 321 1.0E-113 T 14-10-2018 LH59_10570 12f5de83895a1cc657035e6dc045dd35 331 PIRSF PIRSF017082 1 330 1.4E-83 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_10570 12f5de83895a1cc657035e6dc045dd35 331 Gene3D G3DSA:3.40.190.10 133 256 1.0E-113 T 14-10-2018 LH59_00755 5075a2bb613217650fb2eb2421ff2880 209 PIRSF PIRSF006324 1 207 7.5E-51 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 LH59_00755 5075a2bb613217650fb2eb2421ff2880 209 Pfam PF01810 LysE type translocator 16 203 1.9E-30 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 LH59_13740 7cac0389a26df536acd540a2e63a4d7a 323 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 21 80 1.0E-16 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_13740 7cac0389a26df536acd540a2e63a4d7a 323 Pfam PF03466 LysR substrate binding domain 105 310 5.4E-32 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_13740 7cac0389a26df536acd540a2e63a4d7a 323 Gene3D G3DSA:3.40.190.290 109 315 4.4E-29 T 14-10-2018 LH59_13740 7cac0389a26df536acd540a2e63a4d7a 323 Gene3D G3DSA:1.10.10.10 15 102 2.3E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_13740 7cac0389a26df536acd540a2e63a4d7a 323 SUPERFAMILY SSF53850 106 317 9.93E-36 T 14-10-2018 LH59_13740 7cac0389a26df536acd540a2e63a4d7a 323 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 47 6.8E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_13740 7cac0389a26df536acd540a2e63a4d7a 323 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 57 68 6.8E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_13740 7cac0389a26df536acd540a2e63a4d7a 323 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 47 57 6.8E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_13740 7cac0389a26df536acd540a2e63a4d7a 323 SUPERFAMILY SSF46785 18 97 7.72E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_04955 debde554e784754c9764fb51af63f697 85 Pfam PF03776 Septum formation topological specificity factor MinE 14 81 7.1E-27 T 14-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 LH59_04955 debde554e784754c9764fb51af63f697 85 SUPERFAMILY SSF55229 33 83 1.57E-15 T 14-10-2018 IPR036707 Cell division topological specificity factor MinE superfamily GO:0032955|GO:0051301 LH59_04955 debde554e784754c9764fb51af63f697 85 TIGRFAM TIGR01215 minE: cell division topological specificity factor MinE 1 81 6.2E-31 T 14-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 LH59_04955 debde554e784754c9764fb51af63f697 85 Hamap MF_00262 Cell division topological specificity factor [minE]. 3 83 19.108 T 14-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 LH59_04955 debde554e784754c9764fb51af63f697 85 Gene3D G3DSA:3.30.1070.10 1 82 7.6E-29 T 14-10-2018 IPR036707 Cell division topological specificity factor MinE superfamily GO:0032955|GO:0051301 LH59_17865 a6b06af8173dcb6ea19415afa568b6a7 210 Pfam PF03886 ABC-type transport auxiliary lipoprotein component 22 182 1.6E-40 T 14-10-2018 IPR005586 ABC-type transport auxiliary lipoprotein component LH59_17865 a6b06af8173dcb6ea19415afa568b6a7 210 SUPERFAMILY SSF159594 19 189 1.36E-33 T 14-10-2018 LH59_17865 a6b06af8173dcb6ea19415afa568b6a7 210 Gene3D G3DSA:3.40.50.10610 11 189 3.8E-10 T 14-10-2018 LH59_19160 e3ed0f5152fd729c3c41105662e7d352 374 Gene3D G3DSA:3.40.190.170 38 344 1.9E-105 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily LH59_19160 e3ed0f5152fd729c3c41105662e7d352 374 Gene3D G3DSA:3.40.190.10 159 331 1.9E-105 T 14-10-2018 LH59_19160 e3ed0f5152fd729c3c41105662e7d352 374 PIRSF PIRSF039026 6 365 2.1E-130 T 14-10-2018 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like LH59_19160 e3ed0f5152fd729c3c41105662e7d352 374 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 41 323 7.5E-38 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 LH59_24360 851d2b8ddee078876d7c704c4f08b9e5 236 Pfam PF00005 ABC transporter 22 164 1.5E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_24360 851d2b8ddee078876d7c704c4f08b9e5 236 SUPERFAMILY SSF52540 4 227 5.92E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_24360 851d2b8ddee078876d7c704c4f08b9e5 236 Gene3D G3DSA:3.40.50.300 1 236 4.2E-60 T 14-10-2018 LH59_24360 851d2b8ddee078876d7c704c4f08b9e5 236 SMART SM00382 29 213 1.3E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_24360 851d2b8ddee078876d7c704c4f08b9e5 236 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_23945 34574883edd6fabfb118cc785a4c2d76 335 PIRSF PIRSF017082 6 333 1.4E-77 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_23945 34574883edd6fabfb118cc785a4c2d76 335 Gene3D G3DSA:3.40.190.10 135 259 4.9E-101 T 14-10-2018 LH59_23945 34574883edd6fabfb118cc785a4c2d76 335 Gene3D G3DSA:3.40.190.150 37 323 4.9E-101 T 14-10-2018 LH59_23945 34574883edd6fabfb118cc785a4c2d76 335 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 56 330 5.8E-75 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_23945 34574883edd6fabfb118cc785a4c2d76 335 SUPERFAMILY SSF53850 116 293 2.71E-7 T 14-10-2018 LH59_00320 a9d88ba11e4e9a2ff912712c75212e59 284 Gene3D G3DSA:1.10.3720.10 81 277 2.3E-23 T 14-10-2018 IPR035906 MetI-like superfamily LH59_00320 a9d88ba11e4e9a2ff912712c75212e59 284 SUPERFAMILY SSF161098 84 263 1.83E-27 T 14-10-2018 IPR035906 MetI-like superfamily LH59_00320 a9d88ba11e4e9a2ff912712c75212e59 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 274 5.5E-22 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_10360 b1eb28dcd7be01491bae52eef9152e4f 331 PIRSF PIRSF018266 6 328 8.5E-77 T 14-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component LH59_10360 b1eb28dcd7be01491bae52eef9152e4f 331 Pfam PF04773 FecR protein 111 204 2.8E-14 T 14-10-2018 IPR006860 FecR protein LH59_10360 b1eb28dcd7be01491bae52eef9152e4f 331 Gene3D G3DSA:2.60.120.1440 103 241 2.1E-10 T 14-10-2018 LH59_10360 b1eb28dcd7be01491bae52eef9152e4f 331 Pfam PF16220 Domain of unknown function (DUF4880) 17 57 1.3E-10 T 14-10-2018 IPR032623 FecR, N-terminal LH59_17765 1110affb7ee2404f6d1bbcae4b15a29f 256 PIRSF PIRSF039085 1 254 2.4E-103 T 14-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 LH59_17765 1110affb7ee2404f6d1bbcae4b15a29f 256 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_17765 1110affb7ee2404f6d1bbcae4b15a29f 256 SUPERFAMILY SSF52540 5 248 8.05E-76 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_17765 1110affb7ee2404f6d1bbcae4b15a29f 256 TIGRFAM TIGR03005 ectoine_ehuA: ectoine/hydroxyectoine ABC transporter, ATP-binding protein EhuA 5 254 1.4E-105 T 14-10-2018 IPR014343 Ectoine/hydroxyectoine ABC transporter, ATP-binding protein LH59_17765 1110affb7ee2404f6d1bbcae4b15a29f 256 Pfam PF00005 ABC transporter 20 177 3.1E-35 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_17765 1110affb7ee2404f6d1bbcae4b15a29f 256 SMART SM00382 29 241 1.9E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_17765 1110affb7ee2404f6d1bbcae4b15a29f 256 Gene3D G3DSA:3.40.50.300 2 256 1.7E-77 T 14-10-2018 LH59_16560 0f4745898b2db02b552645c2f29111ed 123 TIGRFAM TIGR00494 crcB: protein CrcB 4 117 2.0E-25 T 14-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 LH59_16560 0f4745898b2db02b552645c2f29111ed 123 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 4 114 1.0E-22 T 14-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 LH59_16560 0f4745898b2db02b552645c2f29111ed 123 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 3 121 18.695 T 14-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 LH59_26570 0442158b0cf52b6340ef77240bdeebaa 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 2.1E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_26570 0442158b0cf52b6340ef77240bdeebaa 296 SUPERFAMILY SSF46785 3 113 8.55E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_26570 0442158b0cf52b6340ef77240bdeebaa 296 SUPERFAMILY SSF53850 90 295 9.62E-39 T 14-10-2018 LH59_26570 0442158b0cf52b6340ef77240bdeebaa 296 Gene3D G3DSA:1.10.10.10 3 89 7.1E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_26570 0442158b0cf52b6340ef77240bdeebaa 296 Pfam PF03466 LysR substrate binding domain 90 293 1.7E-35 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_26570 0442158b0cf52b6340ef77240bdeebaa 296 Gene3D G3DSA:3.40.190.290 92 291 2.1E-57 T 14-10-2018 LH59_11355 888b2756eed6ea7ea43acf329b85ec52 505 SMART SM00283 56 324 1.5E-29 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 LH59_11355 888b2756eed6ea7ea43acf329b85ec52 505 SUPERFAMILY SSF58104 62 318 4.19E-48 T 14-10-2018 LH59_11355 888b2756eed6ea7ea43acf329b85ec52 505 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 125 284 1.6E-29 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 LH59_11355 888b2756eed6ea7ea43acf329b85ec52 505 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 183 212 1.4E-14 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_11355 888b2756eed6ea7ea43acf329b85ec52 505 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 154 181 1.4E-14 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_11355 888b2756eed6ea7ea43acf329b85ec52 505 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 77 106 1.4E-14 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_11355 888b2756eed6ea7ea43acf329b85ec52 505 Gene3D G3DSA:1.10.287.950 33 334 8.1E-51 T 14-10-2018 LH59_06275 6ba948201d9134cf5c4ef99c251761ec 132 SUPERFAMILY SSF51316 5 131 4.81E-60 T 14-10-2018 IPR011057 Mss4-like superfamily LH59_06275 6ba948201d9134cf5c4ef99c251761ec 132 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 7 130 38.015 T 14-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 LH59_06275 6ba948201d9134cf5c4ef99c251761ec 132 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 6 131 3.5E-56 T 14-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 LH59_06275 6ba948201d9134cf5c4ef99c251761ec 132 Gene3D G3DSA:2.170.150.20 1 132 2.7E-61 T 14-10-2018 LH59_06275 6ba948201d9134cf5c4ef99c251761ec 132 Pfam PF01641 SelR domain 10 129 5.2E-54 T 14-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 LH59_26800 75abb441f66a8813d1ee8bc1672aef1d 163 Gene3D G3DSA:2.60.40.1890 35 151 2.5E-39 T 14-10-2018 IPR036182 Copper chaperone PCuAC superfamily LH59_26800 75abb441f66a8813d1ee8bc1672aef1d 163 Pfam PF04314 Copper chaperone PCu(A)C 32 141 2.5E-41 T 14-10-2018 IPR007410 Copper chaperone PCuAC LH59_26800 75abb441f66a8813d1ee8bc1672aef1d 163 SUPERFAMILY SSF110087 6 149 1.83E-48 T 14-10-2018 IPR036182 Copper chaperone PCuAC superfamily LH59_11335 a67a159c90643a837868812c65c04bdf 284 Pfam PF01739 CheR methyltransferase, SAM binding domain 89 276 8.9E-57 T 14-10-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal LH59_11335 a67a159c90643a837868812c65c04bdf 284 PIRSF PIRSF000410 4 281 1.6E-95 T 14-10-2018 IPR026024 Chemotaxis protein methyltransferase CheR LH59_11335 a67a159c90643a837868812c65c04bdf 284 Gene3D G3DSA:1.10.155.10 10 87 3.2E-27 T 14-10-2018 IPR036804 Chemotaxis receptor methyltransferase CheR, N-terminal domain superfamily LH59_11335 a67a159c90643a837868812c65c04bdf 284 Pfam PF03705 CheR methyltransferase, all-alpha domain 22 74 3.3E-16 T 14-10-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal LH59_11335 a67a159c90643a837868812c65c04bdf 284 SUPERFAMILY SSF47757 12 88 1.23E-22 T 14-10-2018 LH59_11335 a67a159c90643a837868812c65c04bdf 284 PRINTS PR00996 Glutamate methyltransferase family signature 82 94 9.5E-46 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 LH59_11335 a67a159c90643a837868812c65c04bdf 284 PRINTS PR00996 Glutamate methyltransferase family signature 221 235 9.5E-46 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 LH59_11335 a67a159c90643a837868812c65c04bdf 284 PRINTS PR00996 Glutamate methyltransferase family signature 43 56 9.5E-46 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 LH59_11335 a67a159c90643a837868812c65c04bdf 284 PRINTS PR00996 Glutamate methyltransferase family signature 240 263 9.5E-46 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 LH59_11335 a67a159c90643a837868812c65c04bdf 284 PRINTS PR00996 Glutamate methyltransferase family signature 115 135 9.5E-46 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 LH59_11335 a67a159c90643a837868812c65c04bdf 284 PRINTS PR00996 Glutamate methyltransferase family signature 149 165 9.5E-46 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 LH59_11335 a67a159c90643a837868812c65c04bdf 284 SMART SM00138 21 281 1.1E-102 T 14-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 LH59_11335 a67a159c90643a837868812c65c04bdf 284 Gene3D G3DSA:3.40.50.150 88 281 5.4E-68 T 14-10-2018 LH59_11335 a67a159c90643a837868812c65c04bdf 284 SUPERFAMILY SSF53335 89 278 1.63E-58 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_04145 5e9ddd1a3a8b52d7ba309365cbfa831c 136 Pfam PF03061 Thioesterase superfamily 32 107 2.8E-17 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 LH59_04145 5e9ddd1a3a8b52d7ba309365cbfa831c 136 Gene3D G3DSA:3.10.129.10 6 136 2.0E-37 T 14-10-2018 LH59_04145 5e9ddd1a3a8b52d7ba309365cbfa831c 136 SUPERFAMILY SSF54637 18 134 3.97E-34 T 14-10-2018 IPR029069 HotDog domain superfamily LH59_24580 c0e4d90d2059675ce42d47d989eccb9f 559 Gene3D G3DSA:3.30.70.2450 205 290 8.1E-95 T 14-10-2018 LH59_24580 c0e4d90d2059675ce42d47d989eccb9f 559 SUPERFAMILY SSF51905 28 400 6.37E-64 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_24580 c0e4d90d2059675ce42d47d989eccb9f 559 Pfam PF01494 FAD binding domain 28 364 3.1E-65 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 LH59_24580 c0e4d90d2059675ce42d47d989eccb9f 559 Gene3D G3DSA:3.50.50.60 29 362 8.1E-95 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_24580 c0e4d90d2059675ce42d47d989eccb9f 559 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 28 50 4.6E-36 T 14-10-2018 LH59_24580 c0e4d90d2059675ce42d47d989eccb9f 559 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 316 332 4.6E-36 T 14-10-2018 LH59_24580 c0e4d90d2059675ce42d47d989eccb9f 559 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 334 352 4.6E-36 T 14-10-2018 LH59_24580 c0e4d90d2059675ce42d47d989eccb9f 559 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 301 316 4.6E-36 T 14-10-2018 LH59_24580 c0e4d90d2059675ce42d47d989eccb9f 559 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 176 191 4.6E-36 T 14-10-2018 LH59_24580 c0e4d90d2059675ce42d47d989eccb9f 559 Gene3D G3DSA:3.40.30.120 404 559 2.6E-11 T 14-10-2018 LH59_10350 00a0074f5300995c458d81b380c13645 296 Gene3D G3DSA:2.40.160.90 128 296 9.4E-20 T 14-10-2018 LH59_11805 9d21f1068a5e1f238f1e5cc241c25ff3 332 Gene3D G3DSA:3.30.70.1400 24 116 5.3E-19 T 14-10-2018 LH59_11805 9d21f1068a5e1f238f1e5cc241c25ff3 332 Gene3D G3DSA:3.30.70.1630 21 197 5.3E-19 T 14-10-2018 LH59_11805 9d21f1068a5e1f238f1e5cc241c25ff3 332 Gene3D G3DSA:2.40.30.160 201 312 9.0E-30 T 14-10-2018 LH59_11805 9d21f1068a5e1f238f1e5cc241c25ff3 332 SUPERFAMILY SSF103025 17 247 9.1E-48 T 14-10-2018 LH59_11805 9d21f1068a5e1f238f1e5cc241c25ff3 332 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 192 253 6.7E-27 T 14-10-2018 IPR017703 YgfZ/GcvT conserved site LH59_03450 65169f5ce1e7f369f08ff5698fa36e77 641 SUPERFAMILY SSF52540 76 346 7.89E-17 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_03450 65169f5ce1e7f369f08ff5698fa36e77 641 PIRSF PIRSF000549 1 641 1.1E-294 T 14-10-2018 IPR016230 Serine-protein kinase, PrkA GO:0004672 LH59_03450 65169f5ce1e7f369f08ff5698fa36e77 641 Pfam PF08298 PrkA AAA domain 21 377 2.0E-173 T 14-10-2018 IPR013153 PrkA AAA domain LH59_03450 65169f5ce1e7f369f08ff5698fa36e77 641 SMART SM00763 20 377 8.2E-217 T 14-10-2018 IPR013153 PrkA AAA domain LH59_03450 65169f5ce1e7f369f08ff5698fa36e77 641 Pfam PF06798 PrkA serine protein kinase C-terminal domain 380 633 2.0E-73 T 14-10-2018 IPR010650 PrkA C-terminal domain LH59_15965 b5ec84a95437139c6199f749c62501d3 324 PRINTS PR00111 Alpha/beta hydrolase fold signature 51 66 1.5E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_15965 b5ec84a95437139c6199f749c62501d3 324 PRINTS PR00111 Alpha/beta hydrolase fold signature 111 124 1.5E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_15965 b5ec84a95437139c6199f749c62501d3 324 PRINTS PR00111 Alpha/beta hydrolase fold signature 97 110 1.5E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_15965 b5ec84a95437139c6199f749c62501d3 324 Gene3D G3DSA:3.40.50.1820 3 324 5.1E-94 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_15965 b5ec84a95437139c6199f749c62501d3 324 Pfam PF00561 alpha/beta hydrolase fold 25 159 2.7E-23 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_15965 b5ec84a95437139c6199f749c62501d3 324 SUPERFAMILY SSF53474 3 322 1.54E-70 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_15965 b5ec84a95437139c6199f749c62501d3 324 PRINTS PR00412 Epoxide hydrolase signature 97 110 1.6E-30 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 LH59_15965 b5ec84a95437139c6199f749c62501d3 324 PRINTS PR00412 Epoxide hydrolase signature 111 124 1.6E-30 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 LH59_15965 b5ec84a95437139c6199f749c62501d3 324 PRINTS PR00412 Epoxide hydrolase signature 298 320 1.6E-30 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 LH59_15965 b5ec84a95437139c6199f749c62501d3 324 PRINTS PR00412 Epoxide hydrolase signature 31 49 1.6E-30 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 LH59_15965 b5ec84a95437139c6199f749c62501d3 324 PRINTS PR00412 Epoxide hydrolase signature 260 276 1.6E-30 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 LH59_15965 b5ec84a95437139c6199f749c62501d3 324 PRINTS PR00412 Epoxide hydrolase signature 51 66 1.6E-30 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 LH59_13700 40678e30d0d7d5526eac1a99027558d2 135 SUPERFAMILY SSF54427 6 130 3.28E-17 T 14-10-2018 IPR032710 NTF2-like domain superfamily LH59_13700 40678e30d0d7d5526eac1a99027558d2 135 Pfam PF13577 SnoaL-like domain 6 124 8.9E-7 T 14-10-2018 IPR037401 SnoaL-like domain LH59_13700 40678e30d0d7d5526eac1a99027558d2 135 Gene3D G3DSA:3.10.450.50 4 133 9.8E-17 T 14-10-2018 LH59_23585 d4e11defcd1ef4472c948734566a269c 297 SMART SM00244 36 199 2.9E-4 T 14-10-2018 IPR001107 Band 7 domain LH59_23585 d4e11defcd1ef4472c948734566a269c 297 Gene3D G3DSA:3.30.479.30 64 202 2.0E-9 T 14-10-2018 LH59_23585 d4e11defcd1ef4472c948734566a269c 297 Pfam PF01145 SPFH domain / Band 7 family 40 213 2.7E-31 T 14-10-2018 IPR001107 Band 7 domain LH59_23585 d4e11defcd1ef4472c948734566a269c 297 SUPERFAMILY SSF117892 68 204 3.01E-13 T 14-10-2018 IPR036013 Band 7/SPFH domain superfamily LH59_25640 b03956b870bbeb16b2c256eccc9ecff1 231 SUPERFAMILY SSF47413 1 64 7.88E-9 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 LH59_25640 b03956b870bbeb16b2c256eccc9ecff1 231 Gene3D G3DSA:2.10.109.10 119 229 3.8E-6 T 14-10-2018 LH59_25640 b03956b870bbeb16b2c256eccc9ecff1 231 SMART SM00530 6 60 3.4E-7 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LH59_25640 b03956b870bbeb16b2c256eccc9ecff1 231 Pfam PF00717 Peptidase S24-like 144 211 1.1E-6 T 14-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C LH59_25640 b03956b870bbeb16b2c256eccc9ecff1 231 Gene3D G3DSA:1.10.260.40 1 67 3.6E-10 T 14-10-2018 LH59_25640 b03956b870bbeb16b2c256eccc9ecff1 231 SUPERFAMILY SSF51306 126 227 7.32E-16 T 14-10-2018 IPR036286 LexA/Signal peptidase-like superfamily LH59_17960 3041cd773d04fd667eab667d12164b9f 60 Pfam PF03966 Trm112p-like protein 4 41 5.5E-10 T 14-10-2018 IPR005651 Trm112-like LH59_17960 3041cd773d04fd667eab667d12164b9f 60 Gene3D G3DSA:2.20.25.10 8 60 9.6E-24 T 14-10-2018 LH59_17960 3041cd773d04fd667eab667d12164b9f 60 SUPERFAMILY SSF158997 1 55 1.29E-19 T 14-10-2018 LH59_17960 3041cd773d04fd667eab667d12164b9f 60 Hamap MF_01187 UPF0434 protein YcaR [ycaR]. 1 54 27.178 T 14-10-2018 IPR038053 Uncharacterised protein family UPF0434 LH59_22735 1daf6927f236bc60deac1df6cc623bc2 114 SMART SM01323 20 106 2.3E-43 T 14-10-2018 IPR003849 Preprotein translocase YajC LH59_22735 1daf6927f236bc60deac1df6cc623bc2 114 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 22 106 8.5E-25 T 14-10-2018 IPR003849 Preprotein translocase YajC LH59_22735 1daf6927f236bc60deac1df6cc623bc2 114 Pfam PF02699 Preprotein translocase subunit 24 103 7.4E-31 T 14-10-2018 IPR003849 Preprotein translocase YajC LH59_22735 1daf6927f236bc60deac1df6cc623bc2 114 PRINTS PR01853 Bacterial YajC preprotein translocase signature 22 42 4.4E-17 T 14-10-2018 IPR003849 Preprotein translocase YajC LH59_22735 1daf6927f236bc60deac1df6cc623bc2 114 PRINTS PR01853 Bacterial YajC preprotein translocase signature 60 78 4.4E-17 T 14-10-2018 IPR003849 Preprotein translocase YajC LH59_16975 2d2cb59b916502247038979ce2d9aac2 159 ProSitePatterns PS01117 MarR-type HTH domain signature. 79 113 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site LH59_16975 2d2cb59b916502247038979ce2d9aac2 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 130 150 5.1E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_16975 2d2cb59b916502247038979ce2d9aac2 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 81 96 5.1E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_16975 2d2cb59b916502247038979ce2d9aac2 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 100 116 5.1E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_16975 2d2cb59b916502247038979ce2d9aac2 159 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 80 5.1E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_16975 2d2cb59b916502247038979ce2d9aac2 159 SUPERFAMILY SSF46785 14 155 1.33E-27 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_16975 2d2cb59b916502247038979ce2d9aac2 159 Pfam PF01047 MarR family 62 105 9.8E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_16975 2d2cb59b916502247038979ce2d9aac2 159 Gene3D G3DSA:1.10.10.10 1 155 3.0E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_16975 2d2cb59b916502247038979ce2d9aac2 159 SMART SM00347 33 140 4.7E-18 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_22700 506adcbce1a60c74f88786beaf097fd4 482 SUPERFAMILY SSF56601 33 481 1.84E-90 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like LH59_22700 506adcbce1a60c74f88786beaf097fd4 482 Gene3D G3DSA:3.40.710.10 39 102 4.6E-5 T 14-10-2018 LH59_22700 506adcbce1a60c74f88786beaf097fd4 482 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 439 452 4.1E-24 T 14-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 LH59_22700 506adcbce1a60c74f88786beaf097fd4 482 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 304 326 4.1E-24 T 14-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 LH59_22700 506adcbce1a60c74f88786beaf097fd4 482 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 362 376 4.1E-24 T 14-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 LH59_22700 506adcbce1a60c74f88786beaf097fd4 482 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 377 391 4.1E-24 T 14-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 LH59_22700 506adcbce1a60c74f88786beaf097fd4 482 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 74 93 4.1E-24 T 14-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 LH59_22700 506adcbce1a60c74f88786beaf097fd4 482 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 70 461 4.0E-60 T 14-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 LH59_22700 506adcbce1a60c74f88786beaf097fd4 482 Gene3D G3DSA:3.40.710.10 289 479 1.7E-56 T 14-10-2018 LH59_22700 506adcbce1a60c74f88786beaf097fd4 482 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 47 481 3.4E-81 T 14-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 LH59_22700 506adcbce1a60c74f88786beaf097fd4 482 Gene3D G3DSA:3.50.80.20 103 170 2.3E-10 T 14-10-2018 LH59_25170 d8d1f15426d81a635426e57d9777507d 735 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 78 735 2.6E-95 T 14-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 LH59_25170 d8d1f15426d81a635426e57d9777507d 735 SUPERFAMILY SSF56935 34 735 1.22E-110 T 14-10-2018 LH59_25170 d8d1f15426d81a635426e57d9777507d 735 Gene3D G3DSA:3.55.50.30 1 54 4.4E-6 T 14-10-2018 LH59_25170 d8d1f15426d81a635426e57d9777507d 735 Gene3D G3DSA:2.40.170.20 186 735 2.5E-150 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_25170 d8d1f15426d81a635426e57d9777507d 735 Gene3D G3DSA:2.170.130.10 55 185 4.5E-34 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily LH59_25170 d8d1f15426d81a635426e57d9777507d 735 Pfam PF00593 TonB dependent receptor 274 732 2.8E-42 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_25170 d8d1f15426d81a635426e57d9777507d 735 Pfam PF07715 TonB-dependent Receptor Plug Domain 76 177 9.6E-12 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_18970 de280b4abdc3191b43e1e6244b70145e 182 Gene3D G3DSA:1.10.1740.10 4 80 1.3E-5 T 14-10-2018 LH59_18970 de280b4abdc3191b43e1e6244b70145e 182 Pfam PF04542 Sigma-70 region 2 18 79 1.7E-7 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 LH59_18970 de280b4abdc3191b43e1e6244b70145e 182 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 10 161 1.9E-18 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 LH59_18970 de280b4abdc3191b43e1e6244b70145e 182 Pfam PF08281 Sigma-70, region 4 110 162 2.4E-12 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LH59_18970 de280b4abdc3191b43e1e6244b70145e 182 SUPERFAMILY SSF88659 94 168 2.24E-12 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like LH59_18970 de280b4abdc3191b43e1e6244b70145e 182 Gene3D G3DSA:1.10.10.10 91 170 2.8E-11 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_18970 de280b4abdc3191b43e1e6244b70145e 182 SUPERFAMILY SSF88946 6 75 3.49E-10 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 LH59_01760 c8605faaa135d991cadc2ee903564dcb 180 SUPERFAMILY SSF52833 44 167 9.28E-31 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_01760 c8605faaa135d991cadc2ee903564dcb 180 Gene3D G3DSA:3.40.30.10 16 179 2.8E-33 T 14-10-2018 LH59_01760 c8605faaa135d991cadc2ee903564dcb 180 Pfam PF00578 AhpC/TSA family 46 157 7.6E-19 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 LH59_25020 2e21319d997c12b042383ffc45893e33 335 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 5 213 2.2E-44 T 14-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 LH59_25020 2e21319d997c12b042383ffc45893e33 335 PIRSF PIRSF000267 2 335 4.2E-89 T 14-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 LH59_25020 2e21319d997c12b042383ffc45893e33 335 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 5 324 1.0E-97 T 14-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 LH59_11435 99c2f6dfc331a6193bbdecd34423edf9 327 TIGRFAM TIGR02541 flagell_FlgJ: flagellar rod assembly protein/muramidase FlgJ 17 310 1.0E-118 T 14-10-2018 IPR013377 Peptidoglycan hydrolase FlgJ GO:0016798|GO:0044780 LH59_11435 99c2f6dfc331a6193bbdecd34423edf9 327 Pfam PF10135 Rod binding protein 59 105 2.5E-12 T 14-10-2018 IPR019301 Flagellar protein FlgJ, N-terminal LH59_11435 99c2f6dfc331a6193bbdecd34423edf9 327 SMART SM00047 158 318 2.3E-45 T 14-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 LH59_11435 99c2f6dfc331a6193bbdecd34423edf9 327 Gene3D G3DSA:1.10.530.10 168 307 4.3E-48 T 14-10-2018 LH59_11435 99c2f6dfc331a6193bbdecd34423edf9 327 Gene3D G3DSA:2.10.70.40 202 254 4.3E-48 T 14-10-2018 LH59_11435 99c2f6dfc331a6193bbdecd34423edf9 327 PRINTS PR01002 Flagellar protein FlgJ signature 62 82 6.2E-60 T 14-10-2018 LH59_11435 99c2f6dfc331a6193bbdecd34423edf9 327 PRINTS PR01002 Flagellar protein FlgJ signature 187 205 6.2E-60 T 14-10-2018 LH59_11435 99c2f6dfc331a6193bbdecd34423edf9 327 PRINTS PR01002 Flagellar protein FlgJ signature 273 292 6.2E-60 T 14-10-2018 LH59_11435 99c2f6dfc331a6193bbdecd34423edf9 327 PRINTS PR01002 Flagellar protein FlgJ signature 207 228 6.2E-60 T 14-10-2018 LH59_11435 99c2f6dfc331a6193bbdecd34423edf9 327 PRINTS PR01002 Flagellar protein FlgJ signature 293 311 6.2E-60 T 14-10-2018 LH59_11435 99c2f6dfc331a6193bbdecd34423edf9 327 PRINTS PR01002 Flagellar protein FlgJ signature 229 250 6.2E-60 T 14-10-2018 LH59_11435 99c2f6dfc331a6193bbdecd34423edf9 327 PRINTS PR01002 Flagellar protein FlgJ signature 37 60 6.2E-60 T 14-10-2018 LH59_11435 99c2f6dfc331a6193bbdecd34423edf9 327 PRINTS PR01002 Flagellar protein FlgJ signature 163 186 6.2E-60 T 14-10-2018 LH59_11435 99c2f6dfc331a6193bbdecd34423edf9 327 PRINTS PR01002 Flagellar protein FlgJ signature 251 272 6.2E-60 T 14-10-2018 LH59_11435 99c2f6dfc331a6193bbdecd34423edf9 327 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 176 310 1.1E-20 T 14-10-2018 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 LH59_25740 3b4748409a95e84b468315d56eb7dc8c 362 Gene3D G3DSA:3.40.50.300 2 224 4.4E-66 T 14-10-2018 LH59_25740 3b4748409a95e84b468315d56eb7dc8c 362 Pfam PF00005 ABC transporter 24 163 2.8E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_25740 3b4748409a95e84b468315d56eb7dc8c 362 Pfam PF08402 TOBE domain 282 359 1.2E-6 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 LH59_25740 3b4748409a95e84b468315d56eb7dc8c 362 Gene3D G3DSA:2.40.50.940 225 288 7.1E-9 T 14-10-2018 LH59_25740 3b4748409a95e84b468315d56eb7dc8c 362 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_25740 3b4748409a95e84b468315d56eb7dc8c 362 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 36 357 1.8E-109 T 14-10-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 LH59_25740 3b4748409a95e84b468315d56eb7dc8c 362 SUPERFAMILY SSF52540 6 244 2.93E-85 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_25740 3b4748409a95e84b468315d56eb7dc8c 362 SUPERFAMILY SSF50331 238 358 1.3E-12 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal LH59_25740 3b4748409a95e84b468315d56eb7dc8c 362 SMART SM00382 30 213 1.8E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_25740 3b4748409a95e84b468315d56eb7dc8c 362 Gene3D G3DSA:2.40.50.140 289 340 7.1E-9 T 14-10-2018 LH59_21220 ae213676f0a7bbe20f566f2b96ef0c76 414 SUPERFAMILY SSF111369 52 299 4.45E-81 T 14-10-2018 LH59_21220 ae213676f0a7bbe20f566f2b96ef0c76 414 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 58 292 2.0E-12 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain LH59_21220 ae213676f0a7bbe20f566f2b96ef0c76 414 Gene3D G3DSA:2.40.420.20 303 371 2.4E-110 T 14-10-2018 LH59_21220 ae213676f0a7bbe20f566f2b96ef0c76 414 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 38 373 3.3E-84 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 LH59_21220 ae213676f0a7bbe20f566f2b96ef0c76 414 Gene3D G3DSA:2.40.30.170 51 302 2.4E-110 T 14-10-2018 LH59_21220 ae213676f0a7bbe20f566f2b96ef0c76 414 Pfam PF00529 HlyD membrane-fusion protein of T1SS 38 358 1.7E-7 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 LH59_21220 ae213676f0a7bbe20f566f2b96ef0c76 414 Gene3D G3DSA:1.10.287.470 97 170 2.4E-110 T 14-10-2018 LH59_21220 ae213676f0a7bbe20f566f2b96ef0c76 414 Gene3D G3DSA:2.40.50.100 62 206 2.4E-110 T 14-10-2018 LH59_23735 0b429997dc12a601b6944f46408ae484 393 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 170 181 2.3E-5 T 14-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 LH59_23735 0b429997dc12a601b6944f46408ae484 393 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 111 121 2.3E-5 T 14-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 LH59_23735 0b429997dc12a601b6944f46408ae484 393 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 68 79 2.3E-5 T 14-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 LH59_23735 0b429997dc12a601b6944f46408ae484 393 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 350 367 2.3E-5 T 14-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 LH59_23735 0b429997dc12a601b6944f46408ae484 393 SUPERFAMILY SSF56935 21 393 3.97E-72 T 14-10-2018 LH59_23735 0b429997dc12a601b6944f46408ae484 393 Pfam PF13609 Gram-negative porin 7 373 2.9E-56 T 14-10-2018 LH59_23735 0b429997dc12a601b6944f46408ae484 393 PRINTS PR00184 Neisseria sp. porin signature 70 95 2.3E-7 T 14-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 LH59_23735 0b429997dc12a601b6944f46408ae484 393 PRINTS PR00184 Neisseria sp. porin signature 169 186 2.3E-7 T 14-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 LH59_23735 0b429997dc12a601b6944f46408ae484 393 PRINTS PR00184 Neisseria sp. porin signature 347 371 2.3E-7 T 14-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 LH59_23735 0b429997dc12a601b6944f46408ae484 393 Gene3D G3DSA:2.40.160.10 10 393 6.6E-80 T 14-10-2018 IPR023614 Porin domain superfamily LH59_13600 65f6cc7b21e3255dc590812fdd15f9af 433 Gene3D G3DSA:1.20.1740.10 1 427 3.1E-70 T 14-10-2018 LH59_13600 65f6cc7b21e3255dc590812fdd15f9af 433 Pfam PF13520 Amino acid permease 3 393 1.1E-39 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 LH59_13600 65f6cc7b21e3255dc590812fdd15f9af 433 PIRSF PIRSF006060 1 427 3.6E-57 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 LH59_18885 b987ace7cc6152c6d4b2d296a2b96a45 287 TIGRFAM TIGR00687 pyridox_kin: pyridoxal kinase 22 284 3.4E-51 T 14-10-2018 IPR004625 Pyridoxine kinase GO:0008478|GO:0009443 KEGG: 00750+2.7.1.35|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-6798695|Reactome: R-HSA-964975 LH59_18885 b987ace7cc6152c6d4b2d296a2b96a45 287 Pfam PF08543 Phosphomethylpyrimidine kinase 122 279 1.9E-22 T 14-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 LH59_18885 b987ace7cc6152c6d4b2d296a2b96a45 287 Gene3D G3DSA:3.40.1190.20 19 286 1.3E-73 T 14-10-2018 IPR029056 Ribokinase-like LH59_18885 b987ace7cc6152c6d4b2d296a2b96a45 287 SUPERFAMILY SSF53613 23 282 2.03E-61 T 14-10-2018 IPR029056 Ribokinase-like LH59_06990 133f7417cff179064752dd3e6c37c620 177 SUPERFAMILY SSF88659 95 174 1.13E-17 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like LH59_06990 133f7417cff179064752dd3e6c37c620 177 SUPERFAMILY SSF88946 22 108 1.61E-14 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 LH59_06990 133f7417cff179064752dd3e6c37c620 177 Pfam PF04542 Sigma-70 region 2 23 86 2.9E-15 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 LH59_06990 133f7417cff179064752dd3e6c37c620 177 Gene3D G3DSA:1.10.1740.10 10 85 2.6E-11 T 14-10-2018 LH59_06990 133f7417cff179064752dd3e6c37c620 177 Gene3D G3DSA:1.10.10.10 98 175 3.5E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_06990 133f7417cff179064752dd3e6c37c620 177 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 169 5.3E-24 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 LH59_06990 133f7417cff179064752dd3e6c37c620 177 Pfam PF08281 Sigma-70, region 4 119 171 8.2E-19 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LH59_15795 dde4b7a46946894d155f8f9581b4831e 171 SUPERFAMILY SSF50341 19 160 1.11E-23 T 14-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 LH59_15795 dde4b7a46946894d155f8f9581b4831e 171 Gene3D G3DSA:2.30.30.40 21 147 1.9E-16 T 14-10-2018 LH59_15795 dde4b7a46946894d155f8f9581b4831e 171 Pfam PF01584 CheW-like domain 19 155 7.9E-22 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 LH59_15795 dde4b7a46946894d155f8f9581b4831e 171 SMART SM00260 14 155 4.6E-6 T 14-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 LH59_15795 dde4b7a46946894d155f8f9581b4831e 171 Gene3D G3DSA:2.40.50.180 37 109 1.9E-16 T 14-10-2018 LH59_13280 f12b2adb5c43050e9fdf680ae7b37e0a 244 Pfam PF13618 Gluconate 2-dehydrogenase subunit 3 53 206 2.0E-34 T 14-10-2018 IPR027056 Gluconate 2-dehydrogenase subunit 3 KEGG: 00030+1.1.99.3|MetaCyc: PWY-7165 LH59_26075 d5c1ca35fd020ca48e329bb55584aeb7 181 Pfam PF06073 Bacterial protein of unknown function (DUF934) 70 178 1.5E-33 T 14-10-2018 IPR008318 Uncharacterised conserved protein UCP030820 LH59_26075 d5c1ca35fd020ca48e329bb55584aeb7 181 PIRSF PIRSF030820 19 181 1.3E-47 T 14-10-2018 IPR008318 Uncharacterised conserved protein UCP030820 LH59_13990 48de8b05a9dd8ec3cf24c6aafa84e255 325 Gene3D G3DSA:3.40.190.150 31 315 1.8E-96 T 14-10-2018 LH59_13990 48de8b05a9dd8ec3cf24c6aafa84e255 325 PIRSF PIRSF017082 1 325 5.8E-73 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_13990 48de8b05a9dd8ec3cf24c6aafa84e255 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 320 2.7E-68 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_13990 48de8b05a9dd8ec3cf24c6aafa84e255 325 Gene3D G3DSA:3.40.190.10 129 250 1.8E-96 T 14-10-2018 LH59_13990 48de8b05a9dd8ec3cf24c6aafa84e255 325 SUPERFAMILY SSF53850 32 237 2.97E-8 T 14-10-2018 LH59_24530 d882242c52e1a8fc7a39ed80afd6f996 198 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 18 31 - T 14-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 LH59_24530 d882242c52e1a8fc7a39ed80afd6f996 198 SUPERFAMILY SSF53178 5 193 6.15E-66 T 14-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 LH59_24530 d882242c52e1a8fc7a39ed80afd6f996 198 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 6 192 6.9E-59 T 14-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 LH59_24530 d882242c52e1a8fc7a39ed80afd6f996 198 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 5 186 35.285 T 14-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 LH59_24530 d882242c52e1a8fc7a39ed80afd6f996 198 Gene3D G3DSA:3.40.50.1470 5 197 3.9E-69 T 14-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 LH59_24530 d882242c52e1a8fc7a39ed80afd6f996 198 Pfam PF01195 Peptidyl-tRNA hydrolase 7 188 5.8E-57 T 14-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 LH59_24530 d882242c52e1a8fc7a39ed80afd6f996 198 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 112 122 - T 14-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 LH59_12145 d3aa24bc1fc4cc5e59a4abd346516f5b 384 SUPERFAMILY SSF56935 20 384 5.49E-66 T 14-10-2018 LH59_12145 d3aa24bc1fc4cc5e59a4abd346516f5b 384 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 206 218 8.1E-5 T 14-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 LH59_12145 d3aa24bc1fc4cc5e59a4abd346516f5b 384 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 341 358 8.1E-5 T 14-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 LH59_12145 d3aa24bc1fc4cc5e59a4abd346516f5b 384 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 63 74 8.1E-5 T 14-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 LH59_12145 d3aa24bc1fc4cc5e59a4abd346516f5b 384 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 170 181 8.1E-5 T 14-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 LH59_12145 d3aa24bc1fc4cc5e59a4abd346516f5b 384 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 107 117 8.1E-5 T 14-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 LH59_12145 d3aa24bc1fc4cc5e59a4abd346516f5b 384 PRINTS PR00184 Neisseria sp. porin signature 65 90 5.5E-6 T 14-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 LH59_12145 d3aa24bc1fc4cc5e59a4abd346516f5b 384 PRINTS PR00184 Neisseria sp. porin signature 338 362 5.5E-6 T 14-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 LH59_12145 d3aa24bc1fc4cc5e59a4abd346516f5b 384 Gene3D G3DSA:2.40.160.10 8 384 4.1E-78 T 14-10-2018 IPR023614 Porin domain superfamily LH59_12145 d3aa24bc1fc4cc5e59a4abd346516f5b 384 Pfam PF13609 Gram-negative porin 6 364 7.9E-52 T 14-10-2018 LH59_14135 c8a0b274b26c4e526186a44b852398e0 250 Gene3D G3DSA:3.40.50.300 1 250 7.0E-76 T 14-10-2018 LH59_14135 c8a0b274b26c4e526186a44b852398e0 250 SUPERFAMILY SSF52540 1 245 2.28E-77 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_14135 c8a0b274b26c4e526186a44b852398e0 250 PIRSF PIRSF039085 1 250 1.3E-116 T 14-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 LH59_14135 c8a0b274b26c4e526186a44b852398e0 250 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_14135 c8a0b274b26c4e526186a44b852398e0 250 Pfam PF00005 ABC transporter 17 175 1.0E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_14135 c8a0b274b26c4e526186a44b852398e0 250 SMART SM00382 26 223 1.9E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_24880 1ba8a551c8563e7bef8dd43f3a92580a 1242 Pfam PF04357 TamB, inner membrane protein subunit of TAM complex 909 1238 7.8E-32 T 14-10-2018 IPR007452 Translocation and assembly module TamB LH59_01585 2564298d5b9eab9497946953b7990a4d 569 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 530 556 1.4E-4 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_01585 2564298d5b9eab9497946953b7990a4d 569 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 229 267 5.8E-6 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_01585 2564298d5b9eab9497946953b7990a4d 569 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_01585 2564298d5b9eab9497946953b7990a4d 569 SMART SM00382 29 227 1.7E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_01585 2564298d5b9eab9497946953b7990a4d 569 SMART SM00382 336 528 1.6E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_01585 2564298d5b9eab9497946953b7990a4d 569 SUPERFAMILY SSF52540 4 248 6.39E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_01585 2564298d5b9eab9497946953b7990a4d 569 ProSitePatterns PS00211 ABC transporters family signature. 451 465 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_01585 2564298d5b9eab9497946953b7990a4d 569 Pfam PF00005 ABC transporter 328 478 5.5E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_01585 2564298d5b9eab9497946953b7990a4d 569 Pfam PF00005 ABC transporter 22 177 5.8E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_01585 2564298d5b9eab9497946953b7990a4d 569 Gene3D G3DSA:3.40.50.300 1 286 4.2E-81 T 14-10-2018 LH59_01585 2564298d5b9eab9497946953b7990a4d 569 Gene3D G3DSA:3.40.50.300 306 568 1.5E-89 T 14-10-2018 LH59_01585 2564298d5b9eab9497946953b7990a4d 569 SUPERFAMILY SSF52540 307 550 5.22E-73 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_08225 1298874840e4e07da9c2055539d7a50a 203 Gene3D G3DSA:3.40.30.10 3 196 6.3E-74 T 14-10-2018 LH59_08225 1298874840e4e07da9c2055539d7a50a 203 Pfam PF13410 Glutathione S-transferase, C-terminal domain 120 187 7.4E-8 T 14-10-2018 LH59_08225 1298874840e4e07da9c2055539d7a50a 203 SUPERFAMILY SSF47616 69 201 2.78E-26 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily LH59_08225 1298874840e4e07da9c2055539d7a50a 203 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 75 1.4E-18 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 LH59_08225 1298874840e4e07da9c2055539d7a50a 203 Gene3D G3DSA:1.20.1050.10 79 192 6.3E-74 T 14-10-2018 LH59_08225 1298874840e4e07da9c2055539d7a50a 203 SUPERFAMILY SSF52833 1 100 6.87E-21 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_03815 b9ed3cc8c443d830106463cc11daabf7 226 TIGRFAM TIGR02796 tolQ: protein TolQ 8 223 2.7E-84 T 14-10-2018 IPR014163 Tol-Pal system, TolQ GO:0016021|GO:0043213 LH59_03815 b9ed3cc8c443d830106463cc11daabf7 226 Hamap MF_02202 Tol-Pal system protein TolQ [tolQ]. 7 226 39.796 T 14-10-2018 IPR014163 Tol-Pal system, TolQ GO:0016021|GO:0043213 LH59_03815 b9ed3cc8c443d830106463cc11daabf7 226 Pfam PF01618 MotA/TolQ/ExbB proton channel family 80 211 3.4E-42 T 14-10-2018 IPR002898 MotA/TolQ/ExbB proton channel LH59_01500 700f61c018c465b576b125324547ae8c 686 PIRSF PIRSF015380 1 686 2.8E-216 T 14-10-2018 IPR011385 Putative site-specific recombinase Gcr LH59_01500 700f61c018c465b576b125324547ae8c 686 Pfam PF10136 Site-specific recombinase 34 677 2.6E-228 T 14-10-2018 IPR011385 Putative site-specific recombinase Gcr LH59_16790 4a80b7b665ca13ac7301ae0fdc62dc92 97 Gene3D G3DSA:1.10.260.40 1 81 1.0E-28 T 14-10-2018 LH59_16790 4a80b7b665ca13ac7301ae0fdc62dc92 97 SUPERFAMILY SSF47413 7 87 5.12E-21 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 LH59_16790 4a80b7b665ca13ac7301ae0fdc62dc92 97 TIGRFAM TIGR02607 antidote_HigA: addiction module antidote protein, HigA family 2 81 2.2E-30 T 14-10-2018 IPR013430 Toxin-antitoxin system, antidote protein, HigA GO:0003677 LH59_16790 4a80b7b665ca13ac7301ae0fdc62dc92 97 Pfam PF01381 Helix-turn-helix 19 59 7.1E-6 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LH59_24075 42ea33ff860ec61ca34fc2bb9d4b17bd 534 Pfam PF04675 DNA ligase N terminus 3 166 7.0E-16 T 14-10-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 LH59_24075 42ea33ff860ec61ca34fc2bb9d4b17bd 534 Gene3D G3DSA:3.30.470.30 207 408 5.4E-47 T 14-10-2018 LH59_24075 42ea33ff860ec61ca34fc2bb9d4b17bd 534 Pfam PF04679 ATP dependent DNA ligase C terminal region 429 518 1.1E-9 T 14-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 LH59_24075 42ea33ff860ec61ca34fc2bb9d4b17bd 534 Pfam PF01068 ATP dependent DNA ligase domain 228 408 3.6E-32 T 14-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 LH59_24075 42ea33ff860ec61ca34fc2bb9d4b17bd 534 SUPERFAMILY SSF56091 206 408 1.01E-54 T 14-10-2018 LH59_24075 42ea33ff860ec61ca34fc2bb9d4b17bd 534 TIGRFAM TIGR04120 DNA_lig_bact: DNA ligase, ATP-dependent, PP_1105 family 2 532 1.7E-182 T 14-10-2018 IPR026333 ATP-dependent DNA ligase, PP_1105 family LH59_24075 42ea33ff860ec61ca34fc2bb9d4b17bd 534 Gene3D G3DSA:2.40.50.140 412 534 3.4E-28 T 14-10-2018 LH59_24075 42ea33ff860ec61ca34fc2bb9d4b17bd 534 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 232 240 - T 14-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 LH59_24075 42ea33ff860ec61ca34fc2bb9d4b17bd 534 SUPERFAMILY SSF50249 413 533 4.45E-30 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_01535 3a59dc42f9e46bd025bf068b87a7852d 112 SUPERFAMILY SSF54292 4 93 2.17E-16 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 LH59_01535 3a59dc42f9e46bd025bf068b87a7852d 112 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 7 85 5.0E-9 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 LH59_01535 3a59dc42f9e46bd025bf068b87a7852d 112 Gene3D G3DSA:3.10.20.30 1 105 4.5E-14 T 14-10-2018 IPR012675 Beta-grasp domain superfamily LH59_17125 9d263acdb7c9f07dc3cac8ea9f307661 264 Gene3D G3DSA:3.40.50.300 1 242 2.4E-51 T 14-10-2018 LH59_17125 9d263acdb7c9f07dc3cac8ea9f307661 264 SMART SM00382 27 240 1.1E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_17125 9d263acdb7c9f07dc3cac8ea9f307661 264 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_17125 9d263acdb7c9f07dc3cac8ea9f307661 264 Pfam PF00005 ABC transporter 18 168 1.8E-23 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_17125 9d263acdb7c9f07dc3cac8ea9f307661 264 SUPERFAMILY SSF52540 2 240 7.5E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_14975 799c2a68d6b9b61c6713ae23db7f17c9 239 Pfam PF02230 Phospholipase/Carboxylesterase 12 216 1.1E-31 T 14-10-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 LH59_14975 799c2a68d6b9b61c6713ae23db7f17c9 239 SUPERFAMILY SSF53474 14 214 1.31E-31 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_14975 799c2a68d6b9b61c6713ae23db7f17c9 239 Gene3D G3DSA:3.40.50.1820 12 218 1.5E-34 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_22915 954ec87d531a267fbbd7408805f2a787 185 Gene3D G3DSA:3.40.30.10 99 185 3.4E-22 T 14-10-2018 LH59_22915 954ec87d531a267fbbd7408805f2a787 185 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 39 179 1.7E-42 T 14-10-2018 LH59_22915 954ec87d531a267fbbd7408805f2a787 185 PIRSF PIRSF000216 22 185 2.6E-49 T 14-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_22915 954ec87d531a267fbbd7408805f2a787 185 Gene3D G3DSA:1.10.10.1590 31 98 3.6E-14 T 14-10-2018 LH59_22915 954ec87d531a267fbbd7408805f2a787 185 SUPERFAMILY SSF52833 34 180 4.7E-47 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_05395 9db89b9d9f2b87d279d4f92560e8edce 299 Gene3D G3DSA:3.20.20.70 1 289 2.7E-74 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_05395 9db89b9d9f2b87d279d4f92560e8edce 299 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 16 286 8.8E-62 T 14-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LH59_05395 9db89b9d9f2b87d279d4f92560e8edce 299 SMART SM01130 8 290 5.3E-76 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_05395 9db89b9d9f2b87d279d4f92560e8edce 299 PIRSF PIRSF001365 6 296 8.9E-64 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_05395 9db89b9d9f2b87d279d4f92560e8edce 299 Pfam PF00701 Dihydrodipicolinate synthetase family 9 286 2.9E-55 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_05395 9db89b9d9f2b87d279d4f92560e8edce 299 PRINTS PR00146 Dihydrodipicolinate synthase signature 41 62 2.6E-17 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_05395 9db89b9d9f2b87d279d4f92560e8edce 299 PRINTS PR00146 Dihydrodipicolinate synthase signature 133 150 2.6E-17 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_05395 9db89b9d9f2b87d279d4f92560e8edce 299 PRINTS PR00146 Dihydrodipicolinate synthase signature 108 124 2.6E-17 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_05395 9db89b9d9f2b87d279d4f92560e8edce 299 PRINTS PR00146 Dihydrodipicolinate synthase signature 76 94 2.6E-17 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_05395 9db89b9d9f2b87d279d4f92560e8edce 299 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 44 61 - T 14-10-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LH59_05395 9db89b9d9f2b87d279d4f92560e8edce 299 SUPERFAMILY SSF51569 11 286 1.78E-69 T 14-10-2018 LH59_05395 9db89b9d9f2b87d279d4f92560e8edce 299 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 138 168 - T 14-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 LH59_09620 f25857028486f7a3b8488c2a0fe75a3d 325 Hamap MF_00162 Glutathione synthetase [gshB]. 1 319 154.218 T 14-10-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 LH59_09620 f25857028486f7a3b8488c2a0fe75a3d 325 Pfam PF02951 Prokaryotic glutathione synthetase, N-terminal domain 1 123 1.5E-36 T 14-10-2018 IPR004215 Prokaryotic glutathione synthetase, N-terminal GO:0004363|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 LH59_09620 f25857028486f7a3b8488c2a0fe75a3d 325 Gene3D G3DSA:3.30.470.20 118 298 1.1E-100 T 14-10-2018 LH59_09620 f25857028486f7a3b8488c2a0fe75a3d 325 SUPERFAMILY SSF52440 1 125 1.21E-33 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily LH59_09620 f25857028486f7a3b8488c2a0fe75a3d 325 SUPERFAMILY SSF56059 127 314 2.55E-58 T 14-10-2018 LH59_09620 f25857028486f7a3b8488c2a0fe75a3d 325 TIGRFAM TIGR01380 glut_syn: glutathione synthase 1 315 1.3E-120 T 14-10-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 LH59_09620 f25857028486f7a3b8488c2a0fe75a3d 325 Pfam PF02955 Prokaryotic glutathione synthetase, ATP-grasp domain 127 300 9.1E-74 T 14-10-2018 IPR004218 Prokaryotic glutathione synthetase, ATP-binding GO:0004363|GO:0005524|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 LH59_09620 f25857028486f7a3b8488c2a0fe75a3d 325 Gene3D G3DSA:3.40.50.20 6 117 1.1E-100 T 14-10-2018 LH59_09620 f25857028486f7a3b8488c2a0fe75a3d 325 Gene3D G3DSA:3.30.1490.20 140 204 1.1E-100 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 LH59_06910 be69b26f05ddc71093d9d85b23c856c3 86 Pfam PF03937 Flavinator of succinate dehydrogenase 9 68 4.0E-19 T 14-10-2018 IPR005631 Flavinator of succinate dehydrogenase LH59_06910 be69b26f05ddc71093d9d85b23c856c3 86 Gene3D G3DSA:1.10.150.250 1 82 2.6E-19 T 14-10-2018 IPR036714 Flavinator of succinate dehydrogenase superfamily LH59_06910 be69b26f05ddc71093d9d85b23c856c3 86 SUPERFAMILY SSF109910 3 80 1.7E-18 T 14-10-2018 IPR036714 Flavinator of succinate dehydrogenase superfamily LH59_25805 feb667e5c6bfd0382d04bb2bca739421 250 Pfam PF07729 FCD domain 108 233 1.8E-24 T 14-10-2018 IPR011711 GntR, C-terminal LH59_25805 feb667e5c6bfd0382d04bb2bca739421 250 SMART SM00895 107 234 2.9E-23 T 14-10-2018 IPR011711 GntR, C-terminal LH59_25805 feb667e5c6bfd0382d04bb2bca739421 250 SUPERFAMILY SSF48008 103 239 1.02E-25 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_25805 feb667e5c6bfd0382d04bb2bca739421 250 Gene3D G3DSA:1.20.120.530 99 244 1.9E-28 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_25805 feb667e5c6bfd0382d04bb2bca739421 250 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 57 9.4E-10 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_25805 feb667e5c6bfd0382d04bb2bca739421 250 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 57 73 9.4E-10 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_25805 feb667e5c6bfd0382d04bb2bca739421 250 Gene3D G3DSA:1.10.10.10 14 91 7.3E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_25805 feb667e5c6bfd0382d04bb2bca739421 250 Pfam PF00392 Bacterial regulatory proteins, gntR family 21 83 4.1E-23 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_25805 feb667e5c6bfd0382d04bb2bca739421 250 SMART SM00345 24 83 1.1E-26 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_25805 feb667e5c6bfd0382d04bb2bca739421 250 SUPERFAMILY SSF46785 16 87 6.95E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_17630 caf3b82c1ca29f815d87fde44972336b 310 PIRSF PIRSF018266 8 309 4.0E-57 T 14-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component LH59_17630 caf3b82c1ca29f815d87fde44972336b 310 Pfam PF04773 FecR protein 110 194 4.7E-14 T 14-10-2018 IPR006860 FecR protein LH59_17630 caf3b82c1ca29f815d87fde44972336b 310 Pfam PF16220 Domain of unknown function (DUF4880) 15 56 8.3E-12 T 14-10-2018 IPR032623 FecR, N-terminal LH59_17630 caf3b82c1ca29f815d87fde44972336b 310 Gene3D G3DSA:2.60.120.1440 105 229 1.3E-14 T 14-10-2018 LH59_27875 1a70099775a1e6005faf98501a55942d 138 PRINTS PR00060 Ribosomal protein L16 signature 24 36 2.5E-41 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_27875 1a70099775a1e6005faf98501a55942d 138 PRINTS PR00060 Ribosomal protein L16 signature 88 117 2.5E-41 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_27875 1a70099775a1e6005faf98501a55942d 138 PRINTS PR00060 Ribosomal protein L16 signature 58 87 2.5E-41 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_27875 1a70099775a1e6005faf98501a55942d 138 PRINTS PR00060 Ribosomal protein L16 signature 42 53 2.5E-41 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_27875 1a70099775a1e6005faf98501a55942d 138 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 38.535 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_27875 1a70099775a1e6005faf98501a55942d 138 SUPERFAMILY SSF54686 1 134 2.35E-54 T 14-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 LH59_27875 1a70099775a1e6005faf98501a55942d 138 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 1.8E-50 T 14-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 LH59_27875 1a70099775a1e6005faf98501a55942d 138 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 14-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_27875 1a70099775a1e6005faf98501a55942d 138 Gene3D G3DSA:3.90.1170.10 1 137 3.0E-56 T 14-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 LH59_27875 1a70099775a1e6005faf98501a55942d 138 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 1.4E-59 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_27875 1a70099775a1e6005faf98501a55942d 138 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 14-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_27910 72ceea7006cddb7f9a86ff0b3f7a5700 229 Pfam PF00297 Ribosomal protein L3 80 195 5.6E-18 T 14-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_27910 72ceea7006cddb7f9a86ff0b3f7a5700 229 ProSitePatterns PS00474 Ribosomal protein L3 signature. 115 138 - T 14-10-2018 IPR019926 Ribosomal protein L3, conserved site LH59_27910 72ceea7006cddb7f9a86ff0b3f7a5700 229 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 12 221 38.202 T 14-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_27910 72ceea7006cddb7f9a86ff0b3f7a5700 229 Gene3D G3DSA:2.40.30.10 145 224 3.1E-16 T 14-10-2018 LH59_27910 72ceea7006cddb7f9a86ff0b3f7a5700 229 SUPERFAMILY SSF50447 9 226 3.27E-78 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily LH59_27910 72ceea7006cddb7f9a86ff0b3f7a5700 229 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 14 218 5.0E-84 T 14-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_27910 72ceea7006cddb7f9a86ff0b3f7a5700 229 Gene3D G3DSA:2.40.50.620 42 101 1.3E-11 T 14-10-2018 LH59_02435 e433917720728277857d9bab5d9a5a77 194 Gene3D G3DSA:1.10.3210.10 2 192 3.9E-52 T 14-10-2018 LH59_02435 e433917720728277857d9bab5d9a5a77 194 SUPERFAMILY SSF109604 7 184 7.85E-44 T 14-10-2018 LH59_02435 e433917720728277857d9bab5d9a5a77 194 Pfam PF13023 HD domain 16 179 2.1E-49 T 14-10-2018 IPR006674 HD domain LH59_26595 dff6bae64c1fa4f801beb7e806a8e5d9 383 PIRSF PIRSF000267 7 381 7.6E-115 T 14-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 LH59_26595 dff6bae64c1fa4f801beb7e806a8e5d9 383 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 7 376 3.0E-130 T 14-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 LH59_26595 dff6bae64c1fa4f801beb7e806a8e5d9 383 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 12 367 3.2E-102 T 14-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 LH59_10005 09dd09f7cd73e58b1111838f15dbaeb3 250 Gene3D G3DSA:3.90.550.10 2 238 1.7E-24 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases LH59_10005 09dd09f7cd73e58b1111838f15dbaeb3 250 Pfam PF00535 Glycosyl transferase family 2 7 129 6.0E-15 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 LH59_10005 09dd09f7cd73e58b1111838f15dbaeb3 250 SUPERFAMILY SSF53448 5 232 1.59E-29 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases LH59_18900 d09e1fbea9e227fab94e90e8ea9d121c 354 Pfam PF00639 PPIC-type PPIASE domain 199 282 7.4E-20 T 14-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 LH59_18900 d09e1fbea9e227fab94e90e8ea9d121c 354 Gene3D G3DSA:1.10.4030.30 162 298 5.7E-31 T 14-10-2018 LH59_18900 d09e1fbea9e227fab94e90e8ea9d121c 354 SUPERFAMILY SSF54534 175 283 1.77E-24 T 14-10-2018 LH59_18900 d09e1fbea9e227fab94e90e8ea9d121c 354 Gene3D G3DSA:3.10.50.40 182 285 5.7E-31 T 14-10-2018 LH59_18900 d09e1fbea9e227fab94e90e8ea9d121c 354 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 222 243 - T 14-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 LH59_00935 ab5ae7c112a6fb6757f74b5e1a26307f 134 SUPERFAMILY SSF141734 7 114 5.89E-48 T 14-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 LH59_00935 ab5ae7c112a6fb6757f74b5e1a26307f 134 Gene3D G3DSA:3.10.20.400 5 98 6.4E-40 T 14-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 LH59_00935 ab5ae7c112a6fb6757f74b5e1a26307f 134 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 33 107 7.9E-36 T 14-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 LH59_00935 ab5ae7c112a6fb6757f74b5e1a26307f 134 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 7 111 33.249 T 14-10-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 LH59_00935 ab5ae7c112a6fb6757f74b5e1a26307f 134 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 56 110 6.0E-25 T 14-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 LH59_18140 865220ff8de8ab8c86bd87b521c54bcb 319 Gene3D G3DSA:3.40.190.150 23 309 1.7E-107 T 14-10-2018 LH59_18140 865220ff8de8ab8c86bd87b521c54bcb 319 SUPERFAMILY SSF53850 109 280 8.68E-6 T 14-10-2018 LH59_18140 865220ff8de8ab8c86bd87b521c54bcb 319 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 42 315 5.4E-76 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_18140 865220ff8de8ab8c86bd87b521c54bcb 319 PIRSF PIRSF017082 1 319 6.4E-76 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_18140 865220ff8de8ab8c86bd87b521c54bcb 319 Gene3D G3DSA:3.40.190.10 121 244 1.7E-107 T 14-10-2018 LH59_09540 8044fb8b39e598e633dcaa7cd97c1d49 106 Pfam PF07883 Cupin domain 22 91 2.0E-7 T 14-10-2018 IPR013096 Cupin 2, conserved barrel LH59_09540 8044fb8b39e598e633dcaa7cd97c1d49 106 SUPERFAMILY SSF51182 3 91 1.94E-14 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_09540 8044fb8b39e598e633dcaa7cd97c1d49 106 Gene3D G3DSA:2.60.120.10 1 95 9.2E-31 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_09035 9eeb4a9f6160142e2f488cd92fd35892 186 Pfam PF00583 Acetyltransferase (GNAT) family 58 143 9.9E-10 T 14-10-2018 IPR000182 GNAT domain LH59_09035 9eeb4a9f6160142e2f488cd92fd35892 186 TIGRFAM TIGR02406 ectoine_EctA: diaminobutyrate acetyltransferase 26 182 4.8E-67 T 14-10-2018 IPR012772 L-2,4-diaminobutyric acid acetyltransferase GO:0019491|GO:0033816 KEGG: 00260+2.3.1.178 LH59_09035 9eeb4a9f6160142e2f488cd92fd35892 186 Gene3D G3DSA:3.40.630.30 24 185 1.1E-51 T 14-10-2018 LH59_09035 9eeb4a9f6160142e2f488cd92fd35892 186 SUPERFAMILY SSF55729 25 144 1.11E-18 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_24270 ebbaba1204c8594bcce2efca72b4d055 175 SUPERFAMILY SSF88946 12 103 3.41E-11 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 LH59_24270 ebbaba1204c8594bcce2efca72b4d055 175 SUPERFAMILY SSF88659 94 166 4.8E-10 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like LH59_24270 ebbaba1204c8594bcce2efca72b4d055 175 Pfam PF08281 Sigma-70, region 4 114 166 9.1E-13 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LH59_24270 ebbaba1204c8594bcce2efca72b4d055 175 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 20 164 9.4E-17 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 LH59_24270 ebbaba1204c8594bcce2efca72b4d055 175 Gene3D G3DSA:1.10.1740.10 4 83 4.9E-6 T 14-10-2018 LH59_24270 ebbaba1204c8594bcce2efca72b4d055 175 Pfam PF04542 Sigma-70 region 2 16 82 9.8E-10 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 LH59_24270 ebbaba1204c8594bcce2efca72b4d055 175 Gene3D G3DSA:1.10.10.10 89 169 2.1E-8 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_17505 f18b5b2a71ba06a769ae85f0c5b49da1 369 SUPERFAMILY SSF52096 19 181 5.6E-46 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily LH59_17505 f18b5b2a71ba06a769ae85f0c5b49da1 369 Gene3D G3DSA:3.90.226.10 6 191 8.0E-49 T 14-10-2018 LH59_17505 f18b5b2a71ba06a769ae85f0c5b49da1 369 Pfam PF00574 Clp protease 33 179 1.5E-33 T 14-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA LH59_17505 f18b5b2a71ba06a769ae85f0c5b49da1 369 PRINTS PR00127 Clp protease catalytic subunit P signature 51 71 1.1E-10 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 LH59_17505 f18b5b2a71ba06a769ae85f0c5b49da1 369 PRINTS PR00127 Clp protease catalytic subunit P signature 82 99 1.1E-10 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 LH59_17505 f18b5b2a71ba06a769ae85f0c5b49da1 369 PRINTS PR00127 Clp protease catalytic subunit P signature 158 177 1.1E-10 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 LH59_23515 a004d0dee8855a055f525b6429e8e267 258 SUPERFAMILY SSF51735 6 255 2.04E-57 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_23515 a004d0dee8855a055f525b6429e8e267 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 7.5E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_23515 a004d0dee8855a055f525b6429e8e267 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 7.5E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_23515 a004d0dee8855a055f525b6429e8e267 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 7.5E-6 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_23515 a004d0dee8855a055f525b6429e8e267 258 Gene3D G3DSA:3.40.50.720 1 255 3.0E-61 T 14-10-2018 LH59_23515 a004d0dee8855a055f525b6429e8e267 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 252 7.2E-37 T 14-10-2018 LH59_23515 a004d0dee8855a055f525b6429e8e267 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 4.5E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_23515 a004d0dee8855a055f525b6429e8e267 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 4.5E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_23515 a004d0dee8855a055f525b6429e8e267 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 4.5E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_23515 a004d0dee8855a055f525b6429e8e267 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 4.5E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_23515 a004d0dee8855a055f525b6429e8e267 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 4.5E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_23515 a004d0dee8855a055f525b6429e8e267 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 4.5E-27 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_27510 54f9209abd6efa19bc5bd9d95312221e 427 Pfam PF07399 Putative Na+/H+ antiporter 5 425 2.0E-180 T 14-10-2018 IPR009978 Putative Na+/H+ antiporter LH59_07300 e5a3900172a990682f3c2f49710b921c 119 TIGRFAM TIGR00988 hip: integration host factor, beta subunit 2 91 1.9E-37 T 14-10-2018 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 LH59_07300 e5a3900172a990682f3c2f49710b921c 119 Pfam PF00216 Bacterial DNA-binding protein 1 90 8.0E-28 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 LH59_07300 e5a3900172a990682f3c2f49710b921c 119 Gene3D G3DSA:4.10.520.10 1 94 4.0E-31 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 LH59_07300 e5a3900172a990682f3c2f49710b921c 119 SMART SM00411 1 91 5.2E-36 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 LH59_07300 e5a3900172a990682f3c2f49710b921c 119 SUPERFAMILY SSF47729 1 91 1.62E-28 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 LH59_07300 e5a3900172a990682f3c2f49710b921c 119 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 7.7E-17 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 LH59_07300 e5a3900172a990682f3c2f49710b921c 119 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 7.7E-17 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 LH59_07300 e5a3900172a990682f3c2f49710b921c 119 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 7.7E-17 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 LH59_12185 0a623202689678229e515e9044dd397d 128 Pfam PF10861 Protein of Unknown function (DUF2784) 4 111 4.9E-35 T 14-10-2018 IPR021218 Protein of unknown function DUF2784 LH59_00750 0a70c9ce943eb45b7cbb96600c635488 535 Pfam PF00009 Elongation factor Tu GTP binding domain 10 273 2.6E-52 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_00750 0a70c9ce943eb45b7cbb96600c635488 535 Pfam PF16658 Class II release factor RF3, C-terminal domain 383 511 7.8E-44 T 14-10-2018 IPR032090 Peptide chain release factor 3, C-terminal LH59_00750 0a70c9ce943eb45b7cbb96600c635488 535 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 5 526 2.6E-211 T 14-10-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 LH59_00750 0a70c9ce943eb45b7cbb96600c635488 535 SUPERFAMILY SSF54980 388 459 3.6E-17 T 14-10-2018 IPR035647 EF-G domain III/V-like LH59_00750 0a70c9ce943eb45b7cbb96600c635488 535 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 1 524 51.008 T 14-10-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 LH59_00750 0a70c9ce943eb45b7cbb96600c635488 535 PRINTS PR00315 GTP-binding elongation factor signature 134 143 1.2E-11 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_00750 0a70c9ce943eb45b7cbb96600c635488 535 PRINTS PR00315 GTP-binding elongation factor signature 62 70 1.2E-11 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_00750 0a70c9ce943eb45b7cbb96600c635488 535 PRINTS PR00315 GTP-binding elongation factor signature 98 109 1.2E-11 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_00750 0a70c9ce943eb45b7cbb96600c635488 535 PRINTS PR00315 GTP-binding elongation factor signature 12 25 1.2E-11 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_00750 0a70c9ce943eb45b7cbb96600c635488 535 PRINTS PR00315 GTP-binding elongation factor signature 82 92 1.2E-11 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 LH59_00750 0a70c9ce943eb45b7cbb96600c635488 535 SUPERFAMILY SSF50447 257 387 6.85E-27 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily LH59_00750 0a70c9ce943eb45b7cbb96600c635488 535 Pfam PF03144 Elongation factor Tu domain 2 310 376 3.2E-7 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 LH59_00750 0a70c9ce943eb45b7cbb96600c635488 535 Gene3D G3DSA:3.30.70.3280 386 526 2.4E-47 T 14-10-2018 IPR038467 Peptide chain release factor 3, C-terminal domain superfamily LH59_00750 0a70c9ce943eb45b7cbb96600c635488 535 SUPERFAMILY SSF52540 7 273 5.81E-87 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_00750 0a70c9ce943eb45b7cbb96600c635488 535 Gene3D G3DSA:3.40.50.300 11 373 1.1E-104 T 14-10-2018 LH59_00750 0a70c9ce943eb45b7cbb96600c635488 535 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 55 70 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site LH59_00750 0a70c9ce943eb45b7cbb96600c635488 535 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 144 1.2E-22 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 LH59_00750 0a70c9ce943eb45b7cbb96600c635488 535 Gene3D G3DSA:3.40.50.300 18 271 1.1E-104 T 14-10-2018 LH59_26390 399e00672cef63602b5c4d607f8abc0b 349 Gene3D G3DSA:1.10.1040.10 203 347 4.1E-45 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 LH59_26390 399e00672cef63602b5c4d607f8abc0b 349 SUPERFAMILY SSF48179 194 344 6.12E-49 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 LH59_26390 399e00672cef63602b5c4d607f8abc0b 349 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 202 223 - T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 LH59_26390 399e00672cef63602b5c4d607f8abc0b 349 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 252 269 2.6E-36 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 LH59_26390 399e00672cef63602b5c4d607f8abc0b 349 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 13 30 2.6E-36 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 LH59_26390 399e00672cef63602b5c4d607f8abc0b 349 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 147 167 2.6E-36 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 LH59_26390 399e00672cef63602b5c4d607f8abc0b 349 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 187 211 2.6E-36 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 LH59_26390 399e00672cef63602b5c4d607f8abc0b 349 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 212 236 2.6E-36 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 LH59_26390 399e00672cef63602b5c4d607f8abc0b 349 PIRSF PIRSF000114 7 345 7.4E-91 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 LH59_26390 399e00672cef63602b5c4d607f8abc0b 349 Gene3D G3DSA:3.40.50.720 6 201 7.2E-48 T 14-10-2018 LH59_26390 399e00672cef63602b5c4d607f8abc0b 349 SUPERFAMILY SSF51735 9 194 7.1E-36 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_26390 399e00672cef63602b5c4d607f8abc0b 349 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 194 333 2.1E-45 T 14-10-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 LH59_26390 399e00672cef63602b5c4d607f8abc0b 349 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 11 172 5.7E-36 T 14-10-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 LH59_26390 399e00672cef63602b5c4d607f8abc0b 349 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 9 335 34.341 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 LH59_09165 841cbd0f01f9354a43e8bdde4df991fe 428 PIRSF PIRSF004640 15 424 1.7E-127 T 14-10-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 LH59_09165 841cbd0f01f9354a43e8bdde4df991fe 428 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 23 417 28.435 T 14-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 LH59_09165 841cbd0f01f9354a43e8bdde4df991fe 428 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 21 414 2.8E-115 T 14-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 LH59_09165 841cbd0f01f9354a43e8bdde4df991fe 428 SUPERFAMILY SSF56014 314 422 2.35E-8 T 14-10-2018 LH59_09165 841cbd0f01f9354a43e8bdde4df991fe 428 Gene3D G3DSA:3.20.20.20 18 308 2.8E-93 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 LH59_09165 841cbd0f01f9354a43e8bdde4df991fe 428 Gene3D G3DSA:3.30.413.10 309 426 1.6E-38 T 14-10-2018 LH59_09165 841cbd0f01f9354a43e8bdde4df991fe 428 Pfam PF04551 GcpE protein 35 415 2.1E-112 T 14-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 LH59_25190 aae511bb8ce319c7c534be99afc70672 566 Pfam PF01494 FAD binding domain 24 368 4.6E-59 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 LH59_25190 aae511bb8ce319c7c534be99afc70672 566 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 336 354 6.1E-37 T 14-10-2018 LH59_25190 aae511bb8ce319c7c534be99afc70672 566 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 24 46 6.1E-37 T 14-10-2018 LH59_25190 aae511bb8ce319c7c534be99afc70672 566 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 318 334 6.1E-37 T 14-10-2018 LH59_25190 aae511bb8ce319c7c534be99afc70672 566 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 354 370 6.1E-37 T 14-10-2018 LH59_25190 aae511bb8ce319c7c534be99afc70672 566 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 176 191 6.1E-37 T 14-10-2018 LH59_25190 aae511bb8ce319c7c534be99afc70672 566 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 303 318 6.1E-37 T 14-10-2018 LH59_25190 aae511bb8ce319c7c534be99afc70672 566 Gene3D G3DSA:3.50.50.60 25 365 7.3E-80 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_25190 aae511bb8ce319c7c534be99afc70672 566 Gene3D G3DSA:3.30.70.2450 206 292 7.3E-80 T 14-10-2018 LH59_25190 aae511bb8ce319c7c534be99afc70672 566 SUPERFAMILY SSF51905 23 398 3.96E-52 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_21495 45e5584c8bdf62059f7d961f6f3f0d36 152 SMART SM00411 55 152 3.5E-16 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 LH59_21495 45e5584c8bdf62059f7d961f6f3f0d36 152 Pfam PF00216 Bacterial DNA-binding protein 55 151 3.3E-16 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 LH59_21495 45e5584c8bdf62059f7d961f6f3f0d36 152 Gene3D G3DSA:4.10.520.10 55 151 3.7E-13 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 LH59_21495 45e5584c8bdf62059f7d961f6f3f0d36 152 SUPERFAMILY SSF47729 55 151 7.36E-14 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 LH59_17200 9393adcbae7694bd64d2eb787dce83e8 163 Gene3D G3DSA:3.40.50.2300 1 158 1.2E-58 T 14-10-2018 LH59_17200 9393adcbae7694bd64d2eb787dce83e8 163 SMART SM00226 3 152 1.6E-51 T 14-10-2018 IPR023485 Phosphotyrosine protein phosphatase I LH59_17200 9393adcbae7694bd64d2eb787dce83e8 163 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 5 148 2.5E-42 T 14-10-2018 IPR023485 Phosphotyrosine protein phosphatase I LH59_17200 9393adcbae7694bd64d2eb787dce83e8 163 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 5 22 6.3E-23 T 14-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 LH59_17200 9393adcbae7694bd64d2eb787dce83e8 163 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 48 64 6.3E-23 T 14-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 LH59_17200 9393adcbae7694bd64d2eb787dce83e8 163 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 124 139 6.3E-23 T 14-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 LH59_17200 9393adcbae7694bd64d2eb787dce83e8 163 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 82 97 6.3E-23 T 14-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 LH59_17200 9393adcbae7694bd64d2eb787dce83e8 163 SUPERFAMILY SSF52788 1 153 3.92E-54 T 14-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily LH59_03495 c2d7d46a3331659d056a63139b4cc764 330 SUPERFAMILY SSF53850 120 296 1.52E-10 T 14-10-2018 LH59_03495 c2d7d46a3331659d056a63139b4cc764 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 55 325 3.4E-76 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_03495 c2d7d46a3331659d056a63139b4cc764 330 Gene3D G3DSA:3.40.190.150 35 320 1.4E-102 T 14-10-2018 LH59_03495 c2d7d46a3331659d056a63139b4cc764 330 Gene3D G3DSA:3.40.190.10 132 255 1.4E-102 T 14-10-2018 LH59_03495 c2d7d46a3331659d056a63139b4cc764 330 PIRSF PIRSF017082 2 329 2.5E-73 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_20535 4114356c0569b374f01a157679829883 117 Gene3D G3DSA:3.30.70.100 9 112 4.3E-12 T 14-10-2018 LH59_20535 4114356c0569b374f01a157679829883 117 Pfam PF03992 Antibiotic biosynthesis monooxygenase 17 69 5.2E-6 T 14-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain LH59_20535 4114356c0569b374f01a157679829883 117 SUPERFAMILY SSF54909 10 109 1.44E-14 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel LH59_02295 030eacc92d8635807967f38f89f0f679 294 Pfam PF07859 alpha/beta hydrolase fold 79 171 2.7E-19 T 14-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 LH59_02295 030eacc92d8635807967f38f89f0f679 294 SUPERFAMILY SSF53474 18 283 2.46E-47 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_02295 030eacc92d8635807967f38f89f0f679 294 Gene3D G3DSA:3.40.50.1820 8 289 2.4E-61 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_10120 3f133ecb7ee7d9bb2c5d7fa8dee5db5e 240 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 68 233 1.3E-12 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_10120 3f133ecb7ee7d9bb2c5d7fa8dee5db5e 240 Gene3D G3DSA:1.10.3720.10 41 236 2.1E-18 T 14-10-2018 IPR035906 MetI-like superfamily LH59_10120 3f133ecb7ee7d9bb2c5d7fa8dee5db5e 240 SUPERFAMILY SSF161098 42 223 4.58E-23 T 14-10-2018 IPR035906 MetI-like superfamily LH59_17155 79929d6f26a8b1d110215b49f2e53950 296 Gene3D G3DSA:3.40.50.1380 15 142 3.4E-8 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily LH59_17155 79929d6f26a8b1d110215b49f2e53950 296 Gene3D G3DSA:3.40.50.1380 158 295 1.4E-42 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily LH59_17155 79929d6f26a8b1d110215b49f2e53950 296 SUPERFAMILY SSF52335 154 291 8.24E-33 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily LH59_17155 79929d6f26a8b1d110215b49f2e53950 296 SUPERFAMILY SSF52335 16 140 2.75E-19 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily LH59_17155 79929d6f26a8b1d110215b49f2e53950 296 ProSitePatterns PS01335 Methylglyoxal synthase active site. 222 230 - T 14-10-2018 IPR018148 Methylglyoxal synthase, active site GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 LH59_23960 f397608fe2e39116788c4cc642e77ad7 283 SUPERFAMILY SSF53474 23 269 7.46E-39 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_23960 f397608fe2e39116788c4cc642e77ad7 283 Pfam PF00561 alpha/beta hydrolase fold 52 151 3.0E-10 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_23960 f397608fe2e39116788c4cc642e77ad7 283 Gene3D G3DSA:3.40.50.1820 2 282 3.7E-49 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_17230 940046acb69ae630ce76d3c5df5df49f 217 Gene3D G3DSA:3.90.226.10 14 216 1.3E-83 T 14-10-2018 LH59_17230 940046acb69ae630ce76d3c5df5df49f 217 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 133 146 - T 14-10-2018 IPR033135 ClpP, histidine active site LH59_17230 940046acb69ae630ce76d3c5df5df49f 217 PRINTS PR00127 Clp protease catalytic subunit P signature 189 208 5.6E-53 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 LH59_17230 940046acb69ae630ce76d3c5df5df49f 217 PRINTS PR00127 Clp protease catalytic subunit P signature 40 55 5.6E-53 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 LH59_17230 940046acb69ae630ce76d3c5df5df49f 217 PRINTS PR00127 Clp protease catalytic subunit P signature 132 151 5.6E-53 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 LH59_17230 940046acb69ae630ce76d3c5df5df49f 217 PRINTS PR00127 Clp protease catalytic subunit P signature 111 128 5.6E-53 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 LH59_17230 940046acb69ae630ce76d3c5df5df49f 217 PRINTS PR00127 Clp protease catalytic subunit P signature 80 100 5.6E-53 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 LH59_17230 940046acb69ae630ce76d3c5df5df49f 217 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 24 214 44.63 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 LH59_17230 940046acb69ae630ce76d3c5df5df49f 217 SUPERFAMILY SSF52096 32 214 2.17E-74 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily LH59_17230 940046acb69ae630ce76d3c5df5df49f 217 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 24 212 4.7E-103 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 LH59_17230 940046acb69ae630ce76d3c5df5df49f 217 Pfam PF00574 Clp protease 34 213 3.7E-88 T 14-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA LH59_25690 d32a2bf1223ed84797a4c0b7904f149a 292 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 3.2E-24 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_25690 d32a2bf1223ed84797a4c0b7904f149a 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.9E-11 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_25690 d32a2bf1223ed84797a4c0b7904f149a 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.9E-11 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_25690 d32a2bf1223ed84797a4c0b7904f149a 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.9E-11 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_25690 d32a2bf1223ed84797a4c0b7904f149a 292 Pfam PF03466 LysR substrate binding domain 87 289 5.8E-41 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_25690 d32a2bf1223ed84797a4c0b7904f149a 292 Gene3D G3DSA:3.40.190.10 91 286 2.8E-55 T 14-10-2018 LH59_25690 d32a2bf1223ed84797a4c0b7904f149a 292 SUPERFAMILY SSF53850 89 287 6.43E-36 T 14-10-2018 LH59_25690 d32a2bf1223ed84797a4c0b7904f149a 292 Gene3D G3DSA:1.10.10.10 1 90 1.2E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_25690 d32a2bf1223ed84797a4c0b7904f149a 292 SUPERFAMILY SSF46785 1 84 4.69E-25 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_25690 d32a2bf1223ed84797a4c0b7904f149a 292 Gene3D G3DSA:3.40.190.10 164 269 2.8E-55 T 14-10-2018 LH59_24770 c2cab0a73de5544857d317c3985772f9 501 PIRSF PIRSF012702 1 499 1.3E-181 T 14-10-2018 IPR009197 Microcystin LR degradation protein MlrC LH59_24770 c2cab0a73de5544857d317c3985772f9 501 Pfam PF07364 Metallopeptidase family M81 2 292 1.6E-107 T 14-10-2018 IPR015995 Microcystin LR degradation protein MlrC, N-terminal LH59_24770 c2cab0a73de5544857d317c3985772f9 501 Pfam PF07171 MlrC C-terminus 304 481 8.2E-56 T 14-10-2018 IPR010799 Microcystin LR degradation protein MlrC, C-terminal LH59_14480 978385dfa5f66ccd9c579aff0c0f928d 717 Gene3D G3DSA:1.10.3720.10 507 717 6.1E-40 T 14-10-2018 IPR035906 MetI-like superfamily LH59_14480 978385dfa5f66ccd9c579aff0c0f928d 717 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 193 358 1.8E-7 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_14480 978385dfa5f66ccd9c579aff0c0f928d 717 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 550 712 1.3E-8 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_14480 978385dfa5f66ccd9c579aff0c0f928d 717 SUPERFAMILY SSF161098 78 349 8.0E-26 T 14-10-2018 IPR035906 MetI-like superfamily LH59_14480 978385dfa5f66ccd9c579aff0c0f928d 717 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 76 140 2.1E-11 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 LH59_14480 978385dfa5f66ccd9c579aff0c0f928d 717 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 514 608 6.5E-15 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 LH59_14480 978385dfa5f66ccd9c579aff0c0f928d 717 SUPERFAMILY SSF161098 512 702 2.49E-31 T 14-10-2018 IPR035906 MetI-like superfamily LH59_27645 a6cc347f55ea77c933501a3eb410fde4 375 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 26 372 1.5E-89 T 14-10-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 LH59_27645 a6cc347f55ea77c933501a3eb410fde4 375 Gene3D G3DSA:1.10.3210.10 1 373 5.1E-134 T 14-10-2018 LH59_27645 a6cc347f55ea77c933501a3eb410fde4 375 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 4 372 38.789 T 14-10-2018 IPR023023 dNTP triphosphohydrolase, type 2 GO:0016793 LH59_27645 a6cc347f55ea77c933501a3eb410fde4 375 SMART SM00471 60 208 8.4E-11 T 14-10-2018 IPR003607 HD/PDEase domain LH59_27645 a6cc347f55ea77c933501a3eb410fde4 375 SUPERFAMILY SSF109604 15 373 1.37E-91 T 14-10-2018 LH59_27645 a6cc347f55ea77c933501a3eb410fde4 375 Pfam PF01966 HD domain 64 198 3.4E-15 T 14-10-2018 IPR006674 HD domain LH59_27645 a6cc347f55ea77c933501a3eb410fde4 375 Pfam PF13286 Phosphohydrolase-associated domain 285 370 2.3E-30 T 14-10-2018 IPR026875 Phosphohydrolase-associated domain LH59_08330 01f855a138c6b6b4e160ed7f270ec84d 247 Gene3D G3DSA:2.40.50.230 26 129 9.3E-21 T 14-10-2018 IPR037026 Vgr protein, OB-fold domain superfamily LH59_24140 4a82c4767abdcda518c0611b1b368562 378 Pfam PF01546 Peptidase family M20/M25/M40 66 377 1.2E-34 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 LH59_24140 4a82c4767abdcda518c0611b1b368562 378 Gene3D G3DSA:3.40.630.10 11 365 6.0E-97 T 14-10-2018 LH59_24140 4a82c4767abdcda518c0611b1b368562 378 SUPERFAMILY SSF55031 174 286 2.84E-19 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain LH59_24140 4a82c4767abdcda518c0611b1b368562 378 Pfam PF07687 Peptidase dimerisation domain 171 279 8.5E-23 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain LH59_24140 4a82c4767abdcda518c0611b1b368562 378 TIGRFAM TIGR01892 AcOrn-deacetyl: acetylornithine deacetylase (ArgE) 8 375 1.3E-108 T 14-10-2018 IPR010169 Acetylornithine deacetylase ArgE GO:0005737|GO:0006526|GO:0008777 KEGG: 00220+3.5.1.16|MetaCyc: PWY-5154 LH59_24140 4a82c4767abdcda518c0611b1b368562 378 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 65 74 - T 14-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 LH59_24140 4a82c4767abdcda518c0611b1b368562 378 SUPERFAMILY SSF53187 3 377 3.55E-56 T 14-10-2018 LH59_24140 4a82c4767abdcda518c0611b1b368562 378 Gene3D G3DSA:3.30.70.360 174 289 6.0E-97 T 14-10-2018 LH59_10150 1f3431305beab7334617386a7caf3f84 151 SMART SM00347 25 128 2.4E-4 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_10150 1f3431305beab7334617386a7caf3f84 151 SUPERFAMILY SSF46785 8 142 9.6E-25 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_10150 1f3431305beab7334617386a7caf3f84 151 Gene3D G3DSA:1.10.10.10 2 145 3.7E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_10150 1f3431305beab7334617386a7caf3f84 151 Pfam PF12802 MarR family 31 92 1.9E-12 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_10150 1f3431305beab7334617386a7caf3f84 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 52 68 3.9E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_10150 1f3431305beab7334617386a7caf3f84 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 3.9E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_10150 1f3431305beab7334617386a7caf3f84 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 3.9E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_15020 ed2de596244b0bbee74f97aef1e07b2e 289 SUPERFAMILY SSF51430 14 286 2.36E-64 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily LH59_15020 ed2de596244b0bbee74f97aef1e07b2e 289 Gene3D G3DSA:3.20.20.100 11 287 1.1E-66 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily LH59_15020 ed2de596244b0bbee74f97aef1e07b2e 289 Pfam PF00248 Aldo/keto reductase family 19 286 1.4E-48 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain LH59_14795 a2d6782a380f4df9cdaa780423c39e51 342 Pfam PF09084 NMT1/THI5 like 56 252 5.3E-17 T 14-10-2018 IPR015168 SsuA/THI5-like LH59_14795 a2d6782a380f4df9cdaa780423c39e51 342 Gene3D G3DSA:1.10.8.450 245 263 1.2E-47 T 14-10-2018 LH59_14795 a2d6782a380f4df9cdaa780423c39e51 342 SUPERFAMILY SSF53850 29 254 2.78E-40 T 14-10-2018 LH59_14795 a2d6782a380f4df9cdaa780423c39e51 342 SMART SM00062 30 251 0.0036 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_14795 a2d6782a380f4df9cdaa780423c39e51 342 Gene3D G3DSA:3.40.190.10 31 244 1.2E-47 T 14-10-2018 LH59_14795 a2d6782a380f4df9cdaa780423c39e51 342 TIGRFAM TIGR01729 taurine_ABC_bnd: taurine ABC transporter, periplasmic binding protein 32 338 1.8E-136 T 14-10-2018 IPR010068 Taurine ABC transporter, substrate-binding protein TauA GO:0015734|GO:0042597 LH59_14795 a2d6782a380f4df9cdaa780423c39e51 342 Gene3D G3DSA:3.40.190.10 111 209 1.2E-47 T 14-10-2018 LH59_19675 46a22127de1636c935787ebdd581e93c 302 Gene3D G3DSA:3.40.190.290 95 296 1.3E-53 T 14-10-2018 LH59_19675 46a22127de1636c935787ebdd581e93c 302 Gene3D G3DSA:1.10.10.10 7 92 1.4E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_19675 46a22127de1636c935787ebdd581e93c 302 Pfam PF03466 LysR substrate binding domain 92 296 1.7E-41 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_19675 46a22127de1636c935787ebdd581e93c 302 SUPERFAMILY SSF46785 7 91 1.38E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_19675 46a22127de1636c935787ebdd581e93c 302 SUPERFAMILY SSF53850 94 300 4.16E-40 T 14-10-2018 LH59_19675 46a22127de1636c935787ebdd581e93c 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 1.7E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_17935 2ce6972681c35b3ae5a0ccc62c0736bb 454 Pfam PF13742 OB-fold nucleic acid binding domain 17 109 1.7E-30 T 14-10-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 LH59_17935 2ce6972681c35b3ae5a0ccc62c0736bb 454 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 18 446 1.6E-134 T 14-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 LH59_17935 2ce6972681c35b3ae5a0ccc62c0736bb 454 Pfam PF02601 Exonuclease VII, large subunit 133 442 9.6E-88 T 14-10-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 LH59_17935 2ce6972681c35b3ae5a0ccc62c0736bb 454 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 14 446 27.306 T 14-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 LH59_13745 a506d2d7e8d165244bbfbb2a4d287605 339 Pfam PF00850 Histone deacetylase domain 30 334 2.4E-70 T 14-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 LH59_13745 a506d2d7e8d165244bbfbb2a4d287605 339 Gene3D G3DSA:3.40.800.20 1 338 5.9E-129 T 14-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 LH59_13745 a506d2d7e8d165244bbfbb2a4d287605 339 SUPERFAMILY SSF52768 3 338 5.28E-90 T 14-10-2018 IPR023696 Ureohydrolase domain superfamily LH59_13745 a506d2d7e8d165244bbfbb2a4d287605 339 PRINTS PR01270 Histone deacetylase superfamily signature 153 176 3.3E-16 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 LH59_13745 a506d2d7e8d165244bbfbb2a4d287605 339 PRINTS PR01270 Histone deacetylase superfamily signature 185 200 3.3E-16 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 LH59_13745 a506d2d7e8d165244bbfbb2a4d287605 339 PRINTS PR01270 Histone deacetylase superfamily signature 271 281 3.3E-16 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 LH59_10705 cce12d406a2a1ea4c5f215506158c8d8 344 Gene3D G3DSA:3.50.30.50 53 344 2.8E-10 T 14-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 LH59_10705 cce12d406a2a1ea4c5f215506158c8d8 344 Pfam PF04199 Putative cyclase 85 272 1.1E-15 T 14-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 LH59_10705 cce12d406a2a1ea4c5f215506158c8d8 344 SUPERFAMILY SSF102198 91 343 2.88E-14 T 14-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 LH59_09545 80123e6d3b9b017a1fb7deed69ad037b 544 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 506 532 1.7E-5 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_09545 80123e6d3b9b017a1fb7deed69ad037b 544 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 237 277 4.1E-8 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_09545 80123e6d3b9b017a1fb7deed69ad037b 544 SMART SM00382 36 235 2.2E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_09545 80123e6d3b9b017a1fb7deed69ad037b 544 SMART SM00382 313 512 2.7E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_09545 80123e6d3b9b017a1fb7deed69ad037b 544 Pfam PF00005 ABC transporter 305 453 7.1E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_09545 80123e6d3b9b017a1fb7deed69ad037b 544 ProSitePatterns PS00211 ABC transporters family signature. 427 441 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_09545 80123e6d3b9b017a1fb7deed69ad037b 544 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_09545 80123e6d3b9b017a1fb7deed69ad037b 544 SUPERFAMILY SSF52540 278 526 4.96E-75 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_09545 80123e6d3b9b017a1fb7deed69ad037b 544 Gene3D G3DSA:3.40.50.300 6 276 8.3E-84 T 14-10-2018 LH59_09545 80123e6d3b9b017a1fb7deed69ad037b 544 Gene3D G3DSA:3.40.50.300 277 544 4.8E-86 T 14-10-2018 LH59_09545 80123e6d3b9b017a1fb7deed69ad037b 544 Pfam PF00005 ABC transporter 28 185 1.1E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_09545 80123e6d3b9b017a1fb7deed69ad037b 544 SUPERFAMILY SSF52540 7 257 4.87E-67 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_06355 27d67a7ec2127cae7d792f6ef55993d5 257 Pfam PF00005 ABC transporter 22 177 6.9E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_06355 27d67a7ec2127cae7d792f6ef55993d5 257 Gene3D G3DSA:3.40.50.300 2 247 3.3E-58 T 14-10-2018 LH59_06355 27d67a7ec2127cae7d792f6ef55993d5 257 SUPERFAMILY SSF52540 4 247 1.28E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_06355 27d67a7ec2127cae7d792f6ef55993d5 257 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 225 246 2.6E-6 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal LH59_06355 27d67a7ec2127cae7d792f6ef55993d5 257 SMART SM00382 30 224 1.3E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_12105 bff9c3705c38f13c3a6cb4e8d13ece83 101 Pfam PF13663 Domain of unknown function (DUF4148) 6 59 5.4E-8 T 14-10-2018 IPR025421 Protein of unknown function DUF4148 LH59_19200 d61a54a4c6cd1b1b7bfd7e764f559c22 447 SUPERFAMILY SSF142764 14 443 2.09E-77 T 14-10-2018 LH59_19200 d61a54a4c6cd1b1b7bfd7e764f559c22 447 Gene3D G3DSA:3.40.50.10840 10 265 1.9E-60 T 14-10-2018 IPR037051 Four-carbon acid sugar kinase, N-terminal domain superfamily LH59_19200 d61a54a4c6cd1b1b7bfd7e764f559c22 447 Pfam PF07005 Putative sugar-binding N-terminal domain 15 259 7.0E-43 T 14-10-2018 IPR010737 Four-carbon acid sugar kinase, N-terminal domain LH59_19200 d61a54a4c6cd1b1b7bfd7e764f559c22 447 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 282 440 1.5E-26 T 14-10-2018 IPR031475 Four-carbon acid sugar kinase, C-terminal domain LH59_19200 d61a54a4c6cd1b1b7bfd7e764f559c22 447 Gene3D G3DSA:3.40.980.20 269 446 1.8E-34 T 14-10-2018 LH59_28085 90af26d69bb8623047c627a01f03cbff 403 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 15 383 1.6E-96 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 LH59_28085 90af26d69bb8623047c627a01f03cbff 403 Gene3D G3DSA:3.40.640.10 6 254 2.2E-71 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_28085 90af26d69bb8623047c627a01f03cbff 403 TIGRFAM TIGR01324 cysta_beta_ly_B: cystathionine beta-lyase 17 384 1.7E-122 T 14-10-2018 IPR006233 Cystathionine beta-lyase, bacterial GO:0004121|GO:0005737|GO:0006520 KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8 LH59_28085 90af26d69bb8623047c627a01f03cbff 403 PIRSF PIRSF001434 1 387 8.8E-117 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 LH59_28085 90af26d69bb8623047c627a01f03cbff 403 SUPERFAMILY SSF53383 20 384 1.33E-90 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_28085 90af26d69bb8623047c627a01f03cbff 403 Gene3D G3DSA:3.90.1150.10 255 386 1.2E-37 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_13825 1004da4afd90225f31d8172d8209cdfc 557 Gene3D G3DSA:3.50.50.60 473 541 8.2E-15 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_13825 1004da4afd90225f31d8172d8209cdfc 557 Gene3D G3DSA:3.50.50.60 89 309 3.5E-82 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_13825 1004da4afd90225f31d8172d8209cdfc 557 SUPERFAMILY SSF51905 106 536 9.88E-35 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_13825 1004da4afd90225f31d8172d8209cdfc 557 PIRSF PIRSF038984 1 542 2.0E-235 T 14-10-2018 IPR028348 FAD dependent protein LH59_13825 1004da4afd90225f31d8172d8209cdfc 557 Gene3D G3DSA:3.30.70.2700 1 84 1.1E-18 T 14-10-2018 LH59_10960 52f878f5f10992c8985c1664345525de 197 Gene3D G3DSA:3.40.109.10 10 173 1.7E-38 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 LH59_10960 52f878f5f10992c8985c1664345525de 197 SUPERFAMILY SSF55469 11 192 1.1E-38 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 LH59_10960 52f878f5f10992c8985c1664345525de 197 Pfam PF00881 Nitroreductase family 13 172 1.1E-29 T 14-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 LH59_10960 52f878f5f10992c8985c1664345525de 197 PIRSF PIRSF000232 5 196 1.1E-53 T 14-10-2018 IPR026021 Putative NAD(P)H nitroreductase YdjA-like LH59_11835 386cebe6f3c65b1fc10bccda1d1a939a 245 SUPERFAMILY SSF46785 9 75 4.78E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_11835 386cebe6f3c65b1fc10bccda1d1a939a 245 Pfam PF09339 IclR helix-turn-helix domain 9 57 1.1E-10 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_11835 386cebe6f3c65b1fc10bccda1d1a939a 245 SMART SM00346 6 94 3.0E-7 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_11835 386cebe6f3c65b1fc10bccda1d1a939a 245 Gene3D G3DSA:1.10.10.10 3 73 4.2E-12 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_11835 386cebe6f3c65b1fc10bccda1d1a939a 245 Gene3D G3DSA:3.30.450.40 74 238 7.4E-46 T 14-10-2018 IPR029016 GAF-like domain superfamily LH59_11835 386cebe6f3c65b1fc10bccda1d1a939a 245 Pfam PF01614 Bacterial transcriptional regulator 126 240 2.0E-17 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal LH59_11835 386cebe6f3c65b1fc10bccda1d1a939a 245 SUPERFAMILY SSF55781 71 242 1.5E-36 T 14-10-2018 LH59_00250 ba61f22d22a65c91011f57e82a10123e 304 Gene3D G3DSA:3.40.250.10 187 304 2.0E-17 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily LH59_00250 ba61f22d22a65c91011f57e82a10123e 304 Pfam PF09335 SNARE associated Golgi protein 29 152 4.0E-14 T 14-10-2018 IPR032816 SNARE associated Golgi protein LH59_00250 ba61f22d22a65c91011f57e82a10123e 304 SUPERFAMILY SSF52821 184 303 4.58E-22 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily LH59_00250 ba61f22d22a65c91011f57e82a10123e 304 Pfam PF00581 Rhodanese-like domain 207 299 2.2E-11 T 14-10-2018 IPR001763 Rhodanese-like domain LH59_00250 ba61f22d22a65c91011f57e82a10123e 304 SMART SM00450 206 303 4.1E-13 T 14-10-2018 IPR001763 Rhodanese-like domain LH59_10665 4de3ef3210454caee1bcd59f311ae8e8 398 ProSitePatterns PS00216 Sugar transport proteins signature 1. 62 78 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 LH59_10665 4de3ef3210454caee1bcd59f311ae8e8 398 Pfam PF07690 Major Facilitator Superfamily 9 351 1.8E-39 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_10665 4de3ef3210454caee1bcd59f311ae8e8 398 Gene3D G3DSA:1.20.1250.20 2 385 5.5E-61 T 14-10-2018 LH59_10665 4de3ef3210454caee1bcd59f311ae8e8 398 PRINTS PR01035 Tetracycline resistance protein signature 247 267 1.8E-127 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 LH59_10665 4de3ef3210454caee1bcd59f311ae8e8 398 PRINTS PR01035 Tetracycline resistance protein signature 275 296 1.8E-127 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 LH59_10665 4de3ef3210454caee1bcd59f311ae8e8 398 PRINTS PR01035 Tetracycline resistance protein signature 160 180 1.8E-127 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 LH59_10665 4de3ef3210454caee1bcd59f311ae8e8 398 PRINTS PR01035 Tetracycline resistance protein signature 365 384 1.8E-127 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 LH59_10665 4de3ef3210454caee1bcd59f311ae8e8 398 PRINTS PR01035 Tetracycline resistance protein signature 44 63 1.8E-127 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 LH59_10665 4de3ef3210454caee1bcd59f311ae8e8 398 PRINTS PR01035 Tetracycline resistance protein signature 102 123 1.8E-127 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 LH59_10665 4de3ef3210454caee1bcd59f311ae8e8 398 PRINTS PR01035 Tetracycline resistance protein signature 15 31 1.8E-127 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 LH59_10665 4de3ef3210454caee1bcd59f311ae8e8 398 PRINTS PR01035 Tetracycline resistance protein signature 132 154 1.8E-127 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 LH59_10665 4de3ef3210454caee1bcd59f311ae8e8 398 PRINTS PR01035 Tetracycline resistance protein signature 300 320 1.8E-127 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 LH59_10665 4de3ef3210454caee1bcd59f311ae8e8 398 PRINTS PR01035 Tetracycline resistance protein signature 75 99 1.8E-127 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 LH59_10665 4de3ef3210454caee1bcd59f311ae8e8 398 PRINTS PR01035 Tetracycline resistance protein signature 218 235 1.8E-127 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 LH59_10665 4de3ef3210454caee1bcd59f311ae8e8 398 PRINTS PR01035 Tetracycline resistance protein signature 335 358 1.8E-127 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 LH59_10665 4de3ef3210454caee1bcd59f311ae8e8 398 SUPERFAMILY SSF103473 4 387 1.18E-55 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_15845 b3b77cf2fadf113ea7e4f560ef9275f2 172 SUPERFAMILY SSF52540 14 135 7.79E-20 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_15845 b3b77cf2fadf113ea7e4f560ef9275f2 172 Pfam PF13671 AAA domain 16 157 2.3E-26 T 14-10-2018 LH59_15845 b3b77cf2fadf113ea7e4f560ef9275f2 172 Gene3D G3DSA:3.40.50.300 11 168 1.6E-26 T 14-10-2018 LH59_12790 7b64d99c4216f324f19c763148c45923 258 Gene3D G3DSA:3.40.50.80 100 254 8.6E-42 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain LH59_12790 7b64d99c4216f324f19c763148c45923 258 SUPERFAMILY SSF63380 6 99 4.6E-25 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel LH59_12790 7b64d99c4216f324f19c763148c45923 258 Pfam PF00175 Oxidoreductase NAD-binding domain 113 228 2.0E-7 T 14-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 LH59_12790 7b64d99c4216f324f19c763148c45923 258 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 215 223 1.0E-6 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 LH59_12790 7b64d99c4216f324f19c763148c45923 258 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 136 145 1.0E-6 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 LH59_12790 7b64d99c4216f324f19c763148c45923 258 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 111 130 1.0E-6 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 LH59_12790 7b64d99c4216f324f19c763148c45923 258 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 51 58 1.0E-6 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 LH59_12790 7b64d99c4216f324f19c763148c45923 258 Pfam PF00970 Oxidoreductase FAD-binding domain 16 98 1.4E-8 T 14-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 LH59_12790 7b64d99c4216f324f19c763148c45923 258 SUPERFAMILY SSF52343 102 256 4.06E-40 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain LH59_12790 7b64d99c4216f324f19c763148c45923 258 Gene3D G3DSA:2.40.30.10 1 97 1.8E-27 T 14-10-2018 LH59_04895 f565f105cf9e1d85230e11e982b4f523 329 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 319 8.3E-42 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_04895 f565f105cf9e1d85230e11e982b4f523 329 SUPERFAMILY SSF161098 89 305 5.63E-18 T 14-10-2018 IPR035906 MetI-like superfamily LH59_04895 f565f105cf9e1d85230e11e982b4f523 329 Gene3D G3DSA:1.10.3720.10 83 313 2.8E-22 T 14-10-2018 IPR035906 MetI-like superfamily LH59_11420 0c4b660291d7e253ef450a61fd258763 261 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 184 261 4.7E-25 T 14-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain LH59_11420 0c4b660291d7e253ef450a61fd258763 261 SUPERFAMILY SSF117143 93 223 3.92E-34 T 14-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like LH59_11420 0c4b660291d7e253ef450a61fd258763 261 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 136 1.2E-42 T 14-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G LH59_11420 0c4b660291d7e253ef450a61fd258763 261 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 146 244 4.4E-30 T 14-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G LH59_11420 0c4b660291d7e253ef450a61fd258763 261 TIGRFAM TIGR02488 flgG_G_neg: flagellar basal-body rod protein FlgG 4 260 4.3E-108 T 14-10-2018 IPR012834 Flagellar basal-body rod FlgG GO:0009426|GO:0071973 LH59_11420 0c4b660291d7e253ef450a61fd258763 261 Pfam PF00460 Flagella basal body rod protein 5 35 9.6E-11 T 14-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 LH59_11420 0c4b660291d7e253ef450a61fd258763 261 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 14-10-2018 IPR019776 Flagellar basal body rod protein, conserved site LH59_22415 b7fb0bc4844548dacdb07e95889ffdb9 247 Pfam PF06299 Protein of unknown function (DUF1045) 60 220 1.6E-46 T 14-10-2018 IPR009389 Protein of unknown function DUF1045 KEGG: 00030+2.7.4.23|MetaCyc: PWY-7805|MetaCyc: PWY-7807 LH59_22650 4833fd228a10fafc101e2aa5032e47c9 514 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 10 458 8.1E-164 T 14-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 LH59_22650 4833fd228a10fafc101e2aa5032e47c9 514 SUPERFAMILY SSF143968 350 514 3.14E-66 T 14-10-2018 LH59_22650 4833fd228a10fafc101e2aa5032e47c9 514 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 281 1.4E-74 T 14-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 LH59_22650 4833fd228a10fafc101e2aa5032e47c9 514 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 305 482 4.0E-75 T 14-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 LH59_22650 4833fd228a10fafc101e2aa5032e47c9 514 Hamap MF_01636 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [ubiD]. 1 514 72.842 T 14-10-2018 IPR023677 UbiD decarboxylyase, bacteria GO:0005886|GO:0006744|GO:0008694 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 LH59_22650 4833fd228a10fafc101e2aa5032e47c9 514 Gene3D G3DSA:3.40.1670.10 364 481 1.3E-49 T 14-10-2018 LH59_22650 4833fd228a10fafc101e2aa5032e47c9 514 SUPERFAMILY SSF50475 3 349 6.28E-109 T 14-10-2018 LH59_22650 4833fd228a10fafc101e2aa5032e47c9 514 Gene3D G3DSA:1.20.5.570 482 514 9.2E-16 T 14-10-2018 LH59_18005 e34eef1e4593e909cdeacab45aeb49f2 255 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 20 243 1.6E-52 T 14-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 LH59_18005 e34eef1e4593e909cdeacab45aeb49f2 255 SUPERFAMILY SSF51621 5 251 2.66E-78 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 LH59_18005 e34eef1e4593e909cdeacab45aeb49f2 255 TIGRFAM TIGR03239 GarL: 2-dehydro-3-deoxyglucarate aldolase 7 254 7.2E-137 T 14-10-2018 IPR017648 5-keto-4-deoxy-D-glucarate aldolase GO:0008672|GO:0019394 KEGG: 00053+4.1.2.20 LH59_18005 e34eef1e4593e909cdeacab45aeb49f2 255 Gene3D G3DSA:3.20.20.60 1 255 5.2E-81 T 14-10-2018 LH59_19520 371bd35b968e978d44706b37b0b746d6 399 SUPERFAMILY SSF56601 53 387 9.01E-70 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like LH59_19520 371bd35b968e978d44706b37b0b746d6 399 Pfam PF00144 Beta-lactamase 114 395 6.2E-23 T 14-10-2018 IPR001466 Beta-lactamase-related LH59_19520 371bd35b968e978d44706b37b0b746d6 399 Gene3D G3DSA:1.20.58.710 160 257 1.3E-77 T 14-10-2018 LH59_19520 371bd35b968e978d44706b37b0b746d6 399 Gene3D G3DSA:3.40.710.10 107 380 1.3E-77 T 14-10-2018 LH59_13635 9c5575cbd11eb38afdc2d2c3f864cc06 524 PIRSF PIRSF002741 2 508 3.3E-71 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 LH59_13635 9c5575cbd11eb38afdc2d2c3f864cc06 524 Gene3D G3DSA:3.10.105.10 286 494 9.9E-31 T 14-10-2018 LH59_13635 9c5575cbd11eb38afdc2d2c3f864cc06 524 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 71 443 4.6E-76 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain LH59_13635 9c5575cbd11eb38afdc2d2c3f864cc06 524 SUPERFAMILY SSF53850 25 502 2.4E-106 T 14-10-2018 LH59_13635 9c5575cbd11eb38afdc2d2c3f864cc06 524 Gene3D G3DSA:3.40.190.10 16 285 1.0E-63 T 14-10-2018 LH59_13180 2979c79e953b9ff70abe371db17d0586 112 Pfam PF05957 Bacterial protein of unknown function (DUF883) 33 111 5.5E-20 T 14-10-2018 IPR010279 Inner membrane protein YqjD/ElaB GO:0043022 LH59_11810 fc14f36b57cf1ca7183ea468c42037c9 379 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 10 336 31.266 T 14-10-2018 IPR003770 Endolytic murein transglycosylase LH59_11810 fc14f36b57cf1ca7183ea468c42037c9 379 Pfam PF02618 YceG-like family 45 329 5.6E-75 T 14-10-2018 IPR003770 Endolytic murein transglycosylase LH59_11810 fc14f36b57cf1ca7183ea468c42037c9 379 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 7 332 1.0E-81 T 14-10-2018 IPR003770 Endolytic murein transglycosylase LH59_11810 fc14f36b57cf1ca7183ea468c42037c9 379 Gene3D G3DSA:3.30.160.60 303 335 5.5E-8 T 14-10-2018 LH59_13450 448e212c49c6e600eb4b94a6f6598bb8 177 Pfam PF00440 Bacterial regulatory proteins, tetR family 1 47 3.8E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_13450 448e212c49c6e600eb4b94a6f6598bb8 177 SUPERFAMILY SSF46689 1 65 1.9E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_13450 448e212c49c6e600eb4b94a6f6598bb8 177 SUPERFAMILY SSF48498 69 173 7.69E-19 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily LH59_13450 448e212c49c6e600eb4b94a6f6598bb8 177 Gene3D G3DSA:1.10.357.10 1 176 1.6E-55 T 14-10-2018 LH59_28240 f4b5b5fab2c345b1416ef48bab8db5be 561 Hamap MF_01810 Membrane protein insertase YidC [yidC]. 4 551 24.427 T 14-10-2018 IPR019998 Membrane insertase YidC GO:0016021|GO:0032977 LH59_28240 f4b5b5fab2c345b1416ef48bab8db5be 561 PRINTS PR01900 YidC translocation/secretion protein signature 485 500 5.3E-21 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 LH59_28240 f4b5b5fab2c345b1416ef48bab8db5be 561 PRINTS PR01900 YidC translocation/secretion protein signature 356 372 5.3E-21 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 LH59_28240 f4b5b5fab2c345b1416ef48bab8db5be 561 PRINTS PR01900 YidC translocation/secretion protein signature 504 528 5.3E-21 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 LH59_28240 f4b5b5fab2c345b1416ef48bab8db5be 561 Pfam PF02096 60Kd inner membrane protein 371 548 5.8E-57 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 LH59_28240 f4b5b5fab2c345b1416ef48bab8db5be 561 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 370 549 7.6E-68 T 14-10-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_28240 f4b5b5fab2c345b1416ef48bab8db5be 561 PRINTS PR00701 60kDa inner membrane protein signature 179 199 1.0E-73 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 LH59_28240 f4b5b5fab2c345b1416ef48bab8db5be 561 PRINTS PR00701 60kDa inner membrane protein signature 268 283 1.0E-73 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 LH59_28240 f4b5b5fab2c345b1416ef48bab8db5be 561 PRINTS PR00701 60kDa inner membrane protein signature 2 23 1.0E-73 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 LH59_28240 f4b5b5fab2c345b1416ef48bab8db5be 561 PRINTS PR00701 60kDa inner membrane protein signature 341 361 1.0E-73 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 LH59_28240 f4b5b5fab2c345b1416ef48bab8db5be 561 PRINTS PR00701 60kDa inner membrane protein signature 432 455 1.0E-73 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 LH59_28240 f4b5b5fab2c345b1416ef48bab8db5be 561 PRINTS PR00701 60kDa inner membrane protein signature 479 501 1.0E-73 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 LH59_28240 f4b5b5fab2c345b1416ef48bab8db5be 561 PRINTS PR00701 60kDa inner membrane protein signature 91 112 1.0E-73 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 LH59_28240 f4b5b5fab2c345b1416ef48bab8db5be 561 PRINTS PR00701 60kDa inner membrane protein signature 233 251 1.0E-73 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 LH59_28240 f4b5b5fab2c345b1416ef48bab8db5be 561 PRINTS PR00701 60kDa inner membrane protein signature 515 538 1.0E-73 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 LH59_28240 f4b5b5fab2c345b1416ef48bab8db5be 561 Pfam PF14849 YidC periplasmic domain 86 360 1.0E-83 T 14-10-2018 IPR038210 Membrane insertase YidC, periplasmic domain LH59_28240 f4b5b5fab2c345b1416ef48bab8db5be 561 TIGRFAM TIGR03593 yidC_nterm: membrane protein insertase, YidC/Oxa1 family, N-terminal domain 4 369 3.2E-111 T 14-10-2018 IPR028053 Membrane insertase YidC, N-terminal LH59_28240 f4b5b5fab2c345b1416ef48bab8db5be 561 Gene3D G3DSA:2.70.98.90 81 350 4.6E-81 T 14-10-2018 IPR038221 YidC, periplasmic domain superfamily LH59_19885 a3d29b63955612dd16c440c430ee99f3 336 Gene3D G3DSA:3.30.460.20 6 145 2.7E-12 T 14-10-2018 LH59_19885 a3d29b63955612dd16c440c430ee99f3 336 Gene3D G3DSA:1.20.58.340 146 258 5.7E-23 T 14-10-2018 LH59_19885 a3d29b63955612dd16c440c430ee99f3 336 Gene3D G3DSA:1.20.58.340 279 336 6.0E-22 T 14-10-2018 LH59_19885 a3d29b63955612dd16c440c430ee99f3 336 Pfam PF01544 CorA-like Mg2+ transporter protein 46 332 5.5E-51 T 14-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 LH59_19885 a3d29b63955612dd16c440c430ee99f3 336 SUPERFAMILY SSF143865 15 263 7.32E-50 T 14-10-2018 LH59_19885 a3d29b63955612dd16c440c430ee99f3 336 SUPERFAMILY SSF144083 272 333 4.58E-19 T 14-10-2018 LH59_20620 27f317cc87400151a40305876bc43bdb 284 Pfam PF04228 Putative neutral zinc metallopeptidase 1 279 1.8E-117 T 14-10-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative LH59_20620 27f317cc87400151a40305876bc43bdb 284 SUPERFAMILY SSF55486 94 224 1.52E-5 T 14-10-2018 LH59_24485 5f56e079108a8b8de31aa2d2abd0e73e 832 Pfam PF05170 AsmA family 1 721 9.0E-63 T 14-10-2018 IPR007844 AsmA LH59_20120 6f1fc57e9a75e3967d5c26ee60e90798 350 SUPERFAMILY SSF53659 10 336 1.06E-94 T 14-10-2018 LH59_20120 6f1fc57e9a75e3967d5c26ee60e90798 350 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 12 334 1.0E-97 T 14-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 LH59_20120 6f1fc57e9a75e3967d5c26ee60e90798 350 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 41 328 1.7E-91 T 14-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 LH59_20120 6f1fc57e9a75e3967d5c26ee60e90798 350 Gene3D G3DSA:3.40.718.10 2 335 3.7E-115 T 14-10-2018 LH59_14310 3db0b6eb64d601404c6066a30917b2cd 215 Pfam PF01470 Pyroglutamyl peptidase 3 201 2.9E-79 T 14-10-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like MetaCyc: PWY-7942 LH59_14310 3db0b6eb64d601404c6066a30917b2cd 215 TIGRFAM TIGR00504 pyro_pdase: pyroglutamyl-peptidase I 4 215 1.5E-87 T 14-10-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 MetaCyc: PWY-7942 LH59_14310 3db0b6eb64d601404c6066a30917b2cd 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 132 148 6.8E-46 T 14-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 LH59_14310 3db0b6eb64d601404c6066a30917b2cd 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 80 100 6.8E-46 T 14-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 LH59_14310 3db0b6eb64d601404c6066a30917b2cd 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 162 174 6.8E-46 T 14-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 LH59_14310 3db0b6eb64d601404c6066a30917b2cd 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 4 27 6.8E-46 T 14-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 LH59_14310 3db0b6eb64d601404c6066a30917b2cd 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 62 74 6.8E-46 T 14-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 LH59_14310 3db0b6eb64d601404c6066a30917b2cd 215 Gene3D G3DSA:3.40.630.20 1 215 1.3E-79 T 14-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 LH59_14310 3db0b6eb64d601404c6066a30917b2cd 215 ProSitePatterns PS01334 Pyrrolidone-carboxylate peptidase cysteine active site. 130 144 - T 14-10-2018 IPR033694 Pyroglutamyl peptidase I, Cys active site MetaCyc: PWY-7942 LH59_14310 3db0b6eb64d601404c6066a30917b2cd 215 ProSitePatterns PS01333 Pyrrolidone-carboxylate peptidase glutamic acid active site. 69 85 - T 14-10-2018 IPR033693 Pyroglutamyl peptidase I, Glu active site MetaCyc: PWY-7942 LH59_14310 3db0b6eb64d601404c6066a30917b2cd 215 PIRSF PIRSF015592 1 213 1.2E-81 T 14-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 LH59_14310 3db0b6eb64d601404c6066a30917b2cd 215 Hamap MF_00417 Pyrrolidone-carboxylate peptidase [pcp]. 2 201 40.21 T 14-10-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 MetaCyc: PWY-7942 LH59_14310 3db0b6eb64d601404c6066a30917b2cd 215 SUPERFAMILY SSF53182 1 214 4.97E-71 T 14-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 LH59_20385 adbf7dec53f2d7620890fe8a269ee4bc 166 SUPERFAMILY SSF160387 54 163 1.02E-31 T 14-10-2018 LH59_20385 adbf7dec53f2d7620890fe8a269ee4bc 166 Gene3D G3DSA:3.30.70.2060 54 115 8.7E-26 T 14-10-2018 LH59_20385 adbf7dec53f2d7620890fe8a269ee4bc 166 Pfam PF05573 NosL 15 163 1.4E-46 T 14-10-2018 IPR008719 Nitrous oxide reductase accessory protein NosL LH59_20385 adbf7dec53f2d7620890fe8a269ee4bc 166 Gene3D G3DSA:3.30.70.2050 116 166 3.2E-18 T 14-10-2018 LH59_18130 d08fe64f42a8a6a18a79490e1cccc0b5 130 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 12 127 18.422 T 14-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 LH59_18130 d08fe64f42a8a6a18a79490e1cccc0b5 130 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 14 122 3.2E-23 T 14-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 LH59_27220 42fa094afea32a7051c3a65e2acc45cc 242 SMART SM00671 116 150 0.13 T 14-10-2018 IPR006597 Sel1-like repeat LH59_27220 42fa094afea32a7051c3a65e2acc45cc 242 SMART SM00671 42 77 3.5E-6 T 14-10-2018 IPR006597 Sel1-like repeat LH59_27220 42fa094afea32a7051c3a65e2acc45cc 242 SMART SM00671 151 186 0.015 T 14-10-2018 IPR006597 Sel1-like repeat LH59_27220 42fa094afea32a7051c3a65e2acc45cc 242 SMART SM00671 78 113 4.1E-6 T 14-10-2018 IPR006597 Sel1-like repeat LH59_27220 42fa094afea32a7051c3a65e2acc45cc 242 SUPERFAMILY SSF81901 27 212 3.66E-42 T 14-10-2018 LH59_27220 42fa094afea32a7051c3a65e2acc45cc 242 Gene3D G3DSA:1.25.40.10 21 235 4.3E-51 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_27220 42fa094afea32a7051c3a65e2acc45cc 242 Pfam PF08238 Sel1 repeat 49 77 6.8E-6 T 14-10-2018 IPR006597 Sel1-like repeat LH59_27220 42fa094afea32a7051c3a65e2acc45cc 242 Pfam PF08238 Sel1 repeat 158 186 0.012 T 14-10-2018 IPR006597 Sel1-like repeat LH59_27220 42fa094afea32a7051c3a65e2acc45cc 242 Pfam PF08238 Sel1 repeat 117 150 5.5E-4 T 14-10-2018 IPR006597 Sel1-like repeat LH59_27220 42fa094afea32a7051c3a65e2acc45cc 242 Pfam PF08238 Sel1 repeat 80 112 8.5E-7 T 14-10-2018 IPR006597 Sel1-like repeat LH59_24935 96ab9b5d507d3b6945dad05619a1d908 400 SUPERFAMILY SSF51735 248 380 2.95E-20 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_24935 96ab9b5d507d3b6945dad05619a1d908 400 Gene3D G3DSA:1.10.287.70 133 229 1.6E-17 T 14-10-2018 LH59_24935 96ab9b5d507d3b6945dad05619a1d908 400 Pfam PF02254 TrkA-N domain 251 365 8.2E-17 T 14-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 LH59_24935 96ab9b5d507d3b6945dad05619a1d908 400 SUPERFAMILY SSF81324 132 270 2.75E-22 T 14-10-2018 LH59_24935 96ab9b5d507d3b6945dad05619a1d908 400 Pfam PF07885 Ion channel 155 226 1.5E-15 T 14-10-2018 IPR013099 Potassium channel domain LH59_24935 96ab9b5d507d3b6945dad05619a1d908 400 Gene3D G3DSA:3.40.50.720 246 394 9.4E-28 T 14-10-2018 LH59_02980 0e5585cc8b0a31b794ffd4b111b4df95 414 SUPERFAMILY SSF54427 245 384 1.45E-23 T 14-10-2018 IPR032710 NTF2-like domain superfamily LH59_02980 0e5585cc8b0a31b794ffd4b111b4df95 414 Gene3D G3DSA:3.40.50.1820 5 235 4.2E-57 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_02980 0e5585cc8b0a31b794ffd4b111b4df95 414 Pfam PF01738 Dienelactone hydrolase family 20 234 1.0E-45 T 14-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 LH59_02980 0e5585cc8b0a31b794ffd4b111b4df95 414 Gene3D G3DSA:3.10.450.50 247 379 7.5E-21 T 14-10-2018 LH59_02980 0e5585cc8b0a31b794ffd4b111b4df95 414 SUPERFAMILY SSF53474 6 234 3.33E-45 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_15750 c54ae83ae83428c57ff00b73b5a287ba 372 PRINTS PR00184 Neisseria sp. porin signature 312 336 6.0E-6 T 14-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 LH59_15750 c54ae83ae83428c57ff00b73b5a287ba 372 PRINTS PR00184 Neisseria sp. porin signature 62 87 6.0E-6 T 14-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 LH59_15750 c54ae83ae83428c57ff00b73b5a287ba 372 SUPERFAMILY SSF56935 30 372 4.27E-75 T 14-10-2018 LH59_15750 c54ae83ae83428c57ff00b73b5a287ba 372 Pfam PF13609 Gram-negative porin 22 340 2.4E-49 T 14-10-2018 LH59_15750 c54ae83ae83428c57ff00b73b5a287ba 372 Gene3D G3DSA:2.40.160.10 30 372 6.7E-82 T 14-10-2018 IPR023614 Porin domain superfamily LH59_04340 dec74155a2193b9a017f4aab36151695 151 ProSitePatterns PS01117 MarR-type HTH domain signature. 67 101 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site LH59_04340 dec74155a2193b9a017f4aab36151695 151 Gene3D G3DSA:1.10.10.10 2 146 2.7E-34 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_04340 dec74155a2193b9a017f4aab36151695 151 SMART SM00347 28 128 4.8E-14 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_04340 dec74155a2193b9a017f4aab36151695 151 Pfam PF12802 MarR family 34 92 1.6E-12 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_04340 dec74155a2193b9a017f4aab36151695 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 3.8E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_04340 dec74155a2193b9a017f4aab36151695 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 52 68 3.8E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_04340 dec74155a2193b9a017f4aab36151695 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 3.8E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_04340 dec74155a2193b9a017f4aab36151695 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 118 138 3.8E-7 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_04340 dec74155a2193b9a017f4aab36151695 151 SUPERFAMILY SSF46785 5 143 1.77E-28 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_04515 70a35c786dd28e65d1f2f0510b7890d9 396 SUPERFAMILY SSF47203 231 396 2.42E-22 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 LH59_04515 70a35c786dd28e65d1f2f0510b7890d9 396 Gene3D G3DSA:2.40.110.10 125 234 2.7E-39 T 14-10-2018 LH59_04515 70a35c786dd28e65d1f2f0510b7890d9 396 Gene3D G3DSA:1.20.140.10 235 396 2.0E-37 T 14-10-2018 LH59_04515 70a35c786dd28e65d1f2f0510b7890d9 396 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 393 3.7E-24 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LH59_04515 70a35c786dd28e65d1f2f0510b7890d9 396 SUPERFAMILY SSF56645 2 244 5.63E-78 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 LH59_04515 70a35c786dd28e65d1f2f0510b7890d9 396 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 117 6.7E-19 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 LH59_04515 70a35c786dd28e65d1f2f0510b7890d9 396 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 211 7.4E-23 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 LH59_04515 70a35c786dd28e65d1f2f0510b7890d9 396 Gene3D G3DSA:1.10.540.10 2 119 3.8E-26 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 LH59_02005 482b81ea72dca3a34ab23b1b83f8ca5e 156 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 10 155 1.4E-38 T 14-10-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 LH59_02005 482b81ea72dca3a34ab23b1b83f8ca5e 156 Gene3D G3DSA:1.20.5.620 62 122 4.2E-9 T 14-10-2018 LH59_02005 482b81ea72dca3a34ab23b1b83f8ca5e 156 Pfam PF00430 ATP synthase B/B' CF(0) 6 136 1.3E-27 T 14-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 LH59_02005 482b81ea72dca3a34ab23b1b83f8ca5e 156 Hamap MF_01398 ATP synthase subunit b [atpF]. 1 138 11.435 T 14-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 LH59_02005 482b81ea72dca3a34ab23b1b83f8ca5e 156 SUPERFAMILY SSF81573 67 121 4.18E-7 T 14-10-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily LH59_17435 ce77c17ebdd332d0aa2965ee9f2ae01d 204 Pfam PF06805 Bacteriophage lambda tail assembly protein I 7 89 2.7E-9 T 14-10-2018 IPR010654 Bacteriophage lambda tail assembly I LH59_06655 57f4b3cb589dea6ff67f902d9b257b0a 629 Gene3D G3DSA:3.40.50.12780 30 495 4.4E-95 T 14-10-2018 LH59_06655 57f4b3cb589dea6ff67f902d9b257b0a 629 Gene3D G3DSA:3.30.300.30 498 629 8.9E-26 T 14-10-2018 LH59_06655 57f4b3cb589dea6ff67f902d9b257b0a 629 Pfam PF00501 AMP-binding enzyme 62 502 1.7E-76 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 LH59_06655 57f4b3cb589dea6ff67f902d9b257b0a 629 TIGRFAM TIGR02316 propion_prpE: propionate--CoA ligase 5 629 0.0 T 14-10-2018 IPR012694 Propionate--CoA ligase GO:0019629|GO:0050218 KEGG: 00640+6.2.1.17|MetaCyc: PWY-3941|MetaCyc: PWY-5104|MetaCyc: PWY-5747 LH59_06655 57f4b3cb589dea6ff67f902d9b257b0a 629 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 5 58 1.7E-21 T 14-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 LH59_06655 57f4b3cb589dea6ff67f902d9b257b0a 629 SUPERFAMILY SSF56801 5 625 8.37E-154 T 14-10-2018 LH59_06655 57f4b3cb589dea6ff67f902d9b257b0a 629 ProSitePatterns PS00455 Putative AMP-binding domain signature. 238 249 - T 14-10-2018 IPR020845 AMP-binding, conserved site LH59_06655 57f4b3cb589dea6ff67f902d9b257b0a 629 Pfam PF13193 AMP-binding enzyme C-terminal domain 511 594 2.0E-22 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain LH59_03995 2f89277e9b857e0c72382fd7079cbe4e 354 SUPERFAMILY SSF51556 7 352 1.4E-142 T 14-10-2018 IPR032466 Metal-dependent hydrolase LH59_03995 2f89277e9b857e0c72382fd7079cbe4e 354 Gene3D G3DSA:3.20.20.140 7 353 1.8E-103 T 14-10-2018 LH59_03995 2f89277e9b857e0c72382fd7079cbe4e 354 Pfam PF01979 Amidohydrolase family 16 320 1.3E-21 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 LH59_03995 2f89277e9b857e0c72382fd7079cbe4e 354 ProSitePatterns PS00482 Dihydroorotase signature 1. 16 24 - T 14-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 LH59_03995 2f89277e9b857e0c72382fd7079cbe4e 354 ProSitePatterns PS00483 Dihydroorotase signature 2. 255 266 - T 14-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 LH59_03995 2f89277e9b857e0c72382fd7079cbe4e 354 PIRSF PIRSF001237 5 354 5.7E-135 T 14-10-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 LH59_03995 2f89277e9b857e0c72382fd7079cbe4e 354 Hamap MF_00219 Dihydroorotase [pyrC]. 7 353 46.046 T 14-10-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 LH59_03995 2f89277e9b857e0c72382fd7079cbe4e 354 TIGRFAM TIGR00856 pyrC_dimer: dihydroorotase, homodimeric type 9 351 3.1E-140 T 14-10-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 LH59_08200 6e3cd398f052e51fd3b96dccf01e35df 291 Gene3D G3DSA:3.40.630.40 11 290 1.4E-99 T 14-10-2018 LH59_08200 6e3cd398f052e51fd3b96dccf01e35df 291 SUPERFAMILY SSF53187 18 287 2.13E-87 T 14-10-2018 LH59_08200 6e3cd398f052e51fd3b96dccf01e35df 291 Pfam PF05013 N-formylglutamate amidohydrolase 24 257 2.5E-67 T 14-10-2018 IPR007709 N-formylglutamate amidohydrolase LH59_27550 3ea16f324499fcfc7dc30a80dc73567f 308 Hamap MF_01635 4-hydroxybenzoate octaprenyltransferase [ubiA]. 23 306 26.229 T 14-10-2018 IPR006370 4-hydroxybenzoate polyprenyltransferase-like GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 LH59_27550 3ea16f324499fcfc7dc30a80dc73567f 308 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 85 107 - T 14-10-2018 IPR030470 UbiA prenyltransferase conserved site LH59_27550 3ea16f324499fcfc7dc30a80dc73567f 308 Gene3D G3DSA:1.10.357.140 43 189 2.7E-40 T 14-10-2018 LH59_27550 3ea16f324499fcfc7dc30a80dc73567f 308 Pfam PF01040 UbiA prenyltransferase family 47 292 7.5E-53 T 14-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 LH59_27550 3ea16f324499fcfc7dc30a80dc73567f 308 TIGRFAM TIGR01474 ubiA_proteo: 4-hydroxybenzoate polyprenyl transferase 28 305 6.3E-94 T 14-10-2018 IPR006370 4-hydroxybenzoate polyprenyltransferase-like GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 LH59_27550 3ea16f324499fcfc7dc30a80dc73567f 308 Gene3D G3DSA:1.20.120.1780 190 308 1.3E-18 T 14-10-2018 LH59_01675 ca2b702fef482eba6c816ace85c7e90d 71 Gene3D G3DSA:2.40.50.100 5 69 1.1E-19 T 14-10-2018 LH59_01675 ca2b702fef482eba6c816ace85c7e90d 71 SUPERFAMILY SSF50331 6 69 1.68E-17 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal LH59_01675 ca2b702fef482eba6c816ace85c7e90d 71 Pfam PF03459 TOBE domain 8 67 7.7E-16 T 14-10-2018 IPR005116 Transport-associated OB, type 1 LH59_01675 ca2b702fef482eba6c816ace85c7e90d 71 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 5 69 1.8E-18 T 14-10-2018 IPR004606 Molybdenum-pterin binding GO:0015689 LH59_26700 d0bbd92f8485a3a1c74eb5cd47b6ac5a 248 Pfam PF04972 BON domain 64 122 4.5E-13 T 14-10-2018 IPR007055 BON domain LH59_26700 d0bbd92f8485a3a1c74eb5cd47b6ac5a 248 Pfam PF04972 BON domain 131 194 4.9E-11 T 14-10-2018 IPR007055 BON domain LH59_26700 d0bbd92f8485a3a1c74eb5cd47b6ac5a 248 SMART SM00749 136 199 3.1 T 14-10-2018 IPR014004 Transport-associated and nodulation domain, bacteria LH59_26700 d0bbd92f8485a3a1c74eb5cd47b6ac5a 248 SMART SM00749 60 121 12.0 T 14-10-2018 IPR014004 Transport-associated and nodulation domain, bacteria LH59_21175 09db86e6959f6ca62aa6d2597a4318cc 358 TIGRFAM TIGR02089 TTC: tartrate dehydrogenase 4 353 1.8E-166 T 14-10-2018 IPR011829 Tartrate dehydrogenase GO:0016616|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.93|KEGG: 00650+1.1.1.83 LH59_21175 09db86e6959f6ca62aa6d2597a4318cc 358 SMART SM01329 6 350 1.2E-172 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 LH59_21175 09db86e6959f6ca62aa6d2597a4318cc 358 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 6 349 1.7E-84 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 LH59_21175 09db86e6959f6ca62aa6d2597a4318cc 358 Gene3D G3DSA:3.40.718.10 2 357 1.8E-139 T 14-10-2018 LH59_21175 09db86e6959f6ca62aa6d2597a4318cc 358 SUPERFAMILY SSF53659 3 354 1.04E-114 T 14-10-2018 LH59_21175 09db86e6959f6ca62aa6d2597a4318cc 358 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 244 263 - T 14-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 LH59_15000 8c9e661332045e3110a9c9d589efa043 1062 SUPERFAMILY SSF89550 22 90 2.35E-5 T 14-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 LH59_15000 8c9e661332045e3110a9c9d589efa043 1062 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 304 725 7.0E-147 T 14-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LH59_15000 8c9e661332045e3110a9c9d589efa043 1062 Pfam PF02811 PHP domain 23 128 1.2E-15 T 14-10-2018 IPR004013 PHP domain GO:0003824 LH59_15000 8c9e661332045e3110a9c9d589efa043 1062 SMART SM00481 22 89 4.6E-11 T 14-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal LH59_15000 8c9e661332045e3110a9c9d589efa043 1062 Pfam PF01336 OB-fold nucleic acid binding domain 975 1044 1.9E-6 T 14-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 LH59_15000 8c9e661332045e3110a9c9d589efa043 1062 Pfam PF14579 Helix-hairpin-helix motif 800 893 6.6E-22 T 14-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LH59_15000 8c9e661332045e3110a9c9d589efa043 1062 Hamap MF_01902 Error-prone DNA polymerase [dnaE2]. 21 1062 13.915 T 14-10-2018 IPR023073 DNA polymerase, error-prone GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LH59_15000 8c9e661332045e3110a9c9d589efa043 1062 Gene3D G3DSA:3.20.20.140 17 281 1.0E-53 T 14-10-2018 LH59_15000 8c9e661332045e3110a9c9d589efa043 1062 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 22 1006 4.0E-156 T 14-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LH59_23020 967c76843244ada50cb5e02ff8b5cf8c 234 Gene3D G3DSA:3.40.50.720 1 234 5.0E-71 T 14-10-2018 LH59_23020 967c76843244ada50cb5e02ff8b5cf8c 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 7.0E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_23020 967c76843244ada50cb5e02ff8b5cf8c 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 7.0E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_23020 967c76843244ada50cb5e02ff8b5cf8c 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 214 7.0E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_23020 967c76843244ada50cb5e02ff8b5cf8c 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 7.0E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_23020 967c76843244ada50cb5e02ff8b5cf8c 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 7.0E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_23020 967c76843244ada50cb5e02ff8b5cf8c 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 7.0E-32 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_23020 967c76843244ada50cb5e02ff8b5cf8c 234 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 231 4.3E-50 T 14-10-2018 LH59_23020 967c76843244ada50cb5e02ff8b5cf8c 234 SUPERFAMILY SSF51735 4 231 1.56E-64 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_22560 64930e43a7ecb055d88c37f3ee4237f6 314 Pfam PF01515 Phosphate acetyl/butaryl transferase 85 299 3.9E-43 T 14-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 LH59_22560 64930e43a7ecb055d88c37f3ee4237f6 314 Gene3D G3DSA:3.40.718.10 6 303 1.4E-96 T 14-10-2018 LH59_22560 64930e43a7ecb055d88c37f3ee4237f6 314 SUPERFAMILY SSF53659 9 303 7.67E-67 T 14-10-2018 LH59_22560 64930e43a7ecb055d88c37f3ee4237f6 314 PIRSF PIRSF000428 6 305 9.9E-86 T 14-10-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 LH59_25745 a6698a95d8e63d124e26330d8de5d51c 591 SUPERFAMILY SSF161098 14 277 4.02E-50 T 14-10-2018 IPR035906 MetI-like superfamily LH59_25745 a6698a95d8e63d124e26330d8de5d51c 591 SUPERFAMILY SSF161098 338 589 4.58E-51 T 14-10-2018 IPR035906 MetI-like superfamily LH59_25745 a6698a95d8e63d124e26330d8de5d51c 591 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 410 587 1.3E-9 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_25745 a6698a95d8e63d124e26330d8de5d51c 591 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 274 5.7E-9 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_25745 a6698a95d8e63d124e26330d8de5d51c 591 Gene3D G3DSA:1.10.3720.10 335 589 7.4E-49 T 14-10-2018 IPR035906 MetI-like superfamily LH59_25745 a6698a95d8e63d124e26330d8de5d51c 591 Gene3D G3DSA:1.10.3720.10 17 286 3.2E-56 T 14-10-2018 IPR035906 MetI-like superfamily LH59_05470 b1d043c6fd34a27f6dc80b86d419d73d 795 Pfam PF01580 FtsK/SpoIIIE family 409 618 2.4E-64 T 14-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 LH59_05470 b1d043c6fd34a27f6dc80b86d419d73d 795 Gene3D G3DSA:1.10.10.10 721 786 4.2E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_05470 b1d043c6fd34a27f6dc80b86d419d73d 795 Gene3D G3DSA:3.40.50.300 406 703 7.4E-116 T 14-10-2018 LH59_05470 b1d043c6fd34a27f6dc80b86d419d73d 795 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 31 219 1.1E-44 T 14-10-2018 IPR025199 DNA translocase FtsK, 4TM region LH59_05470 b1d043c6fd34a27f6dc80b86d419d73d 795 SMART SM00382 444 639 0.0059 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_05470 b1d043c6fd34a27f6dc80b86d419d73d 795 Gene3D G3DSA:3.30.980.40 301 405 2.4E-32 T 14-10-2018 LH59_05470 b1d043c6fd34a27f6dc80b86d419d73d 795 Pfam PF09397 Ftsk gamma domain 727 787 4.7E-27 T 14-10-2018 IPR018541 FtsK gamma domain LH59_05470 b1d043c6fd34a27f6dc80b86d419d73d 795 SUPERFAMILY SSF46785 725 789 1.05E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_05470 b1d043c6fd34a27f6dc80b86d419d73d 795 SMART SM00843 725 790 7.6E-39 T 14-10-2018 IPR018541 FtsK gamma domain LH59_05470 b1d043c6fd34a27f6dc80b86d419d73d 795 SUPERFAMILY SSF52540 426 689 5.31E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_22940 90b96abe563acc4ca05f2d3081eb1051 555 SUPERFAMILY SSF103473 26 492 1.44E-45 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_22940 90b96abe563acc4ca05f2d3081eb1051 555 Pfam PF07690 Major Facilitator Superfamily 40 441 1.1E-40 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_22940 90b96abe563acc4ca05f2d3081eb1051 555 Gene3D G3DSA:1.20.1250.20 24 486 5.6E-33 T 14-10-2018 LH59_25140 f24be41ab2ec3a0006bda3a573e9f97d 46 Pfam PF00444 Ribosomal protein L36 1 41 1.5E-18 T 14-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_25140 f24be41ab2ec3a0006bda3a573e9f97d 46 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 41 1.4E-9 T 14-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_25140 f24be41ab2ec3a0006bda3a573e9f97d 46 ProSitePatterns PS00828 Ribosomal protein L36 signature. 14 40 - T 14-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_25140 f24be41ab2ec3a0006bda3a573e9f97d 46 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 41 18.124 T 14-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_25140 f24be41ab2ec3a0006bda3a573e9f97d 46 SUPERFAMILY SSF57840 1 41 8.37E-15 T 14-10-2018 IPR035977 Ribosomal protein L36 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_25140 f24be41ab2ec3a0006bda3a573e9f97d 46 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 17 41 3.0E-4 T 14-10-2018 LH59_12600 cd95fc5bda7b8f544ddfc69b3593a1bd 353 Gene3D G3DSA:3.60.60.10 78 345 1.5E-50 T 14-10-2018 LH59_12600 cd95fc5bda7b8f544ddfc69b3593a1bd 353 Pfam PF03417 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 109 332 1.2E-51 T 14-10-2018 IPR005079 Peptidase C45 LH59_00985 e5e120c9e74b6004faa1d26c0756ee1b 270 Pfam PF01061 ABC-2 type transporter 25 233 5.0E-35 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 LH59_00985 e5e120c9e74b6004faa1d26c0756ee1b 270 PRINTS PR00164 ABC-2 type transport system membrane protein signature 190 209 1.6E-9 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 LH59_00985 e5e120c9e74b6004faa1d26c0756ee1b 270 PRINTS PR00164 ABC-2 type transport system membrane protein signature 72 94 1.6E-9 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 LH59_00985 e5e120c9e74b6004faa1d26c0756ee1b 270 PRINTS PR00164 ABC-2 type transport system membrane protein signature 210 229 1.6E-9 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 LH59_00985 e5e120c9e74b6004faa1d26c0756ee1b 270 PIRSF PIRSF006648 1 266 1.6E-24 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 LH59_28155 cb88bcefd981761f691f19d7d7497a21 332 Gene3D G3DSA:3.40.190.150 35 322 1.8E-53 T 14-10-2018 LH59_28155 cb88bcefd981761f691f19d7d7497a21 332 Gene3D G3DSA:3.40.190.10 129 257 1.8E-53 T 14-10-2018 LH59_28155 cb88bcefd981761f691f19d7d7497a21 332 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 114 326 9.8E-20 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_28155 cb88bcefd981761f691f19d7d7497a21 332 PIRSF PIRSF017082 1 332 2.9E-73 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_28155 cb88bcefd981761f691f19d7d7497a21 332 SUPERFAMILY SSF53850 101 236 3.46E-9 T 14-10-2018 LH59_01340 105272f69c59a5a1673aebba79b0c79c 355 Gene3D G3DSA:3.30.1780.10 20 333 3.2E-121 T 14-10-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 LH59_01340 105272f69c59a5a1673aebba79b0c79c 355 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 20 313 2.5E-95 T 14-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 LH59_01340 105272f69c59a5a1673aebba79b0c79c 355 PIRSF PIRSF001439 33 323 1.7E-47 T 14-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 LH59_01340 105272f69c59a5a1673aebba79b0c79c 355 SUPERFAMILY SSF51735 2 337 8.65E-93 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_01340 105272f69c59a5a1673aebba79b0c79c 355 Gene3D G3DSA:3.40.50.720 126 295 3.2E-121 T 14-10-2018 LH59_00270 8222561fa4476d144a77e7c42eb078b4 189 SMART SM00903 14 160 9.0E-34 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 LH59_00270 8222561fa4476d144a77e7c42eb078b4 189 Pfam PF01613 Flavin reductase like domain 19 152 8.9E-25 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 LH59_00270 8222561fa4476d144a77e7c42eb078b4 189 Gene3D G3DSA:2.30.110.10 1 186 2.1E-55 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 LH59_00270 8222561fa4476d144a77e7c42eb078b4 189 SUPERFAMILY SSF50475 2 182 8.83E-46 T 14-10-2018 LH59_24235 4803f4b72b6c629e5a8f3b5e735adce6 258 Gene3D G3DSA:3.30.450.20 15 143 1.5E-22 T 14-10-2018 LH59_24235 4803f4b72b6c629e5a8f3b5e735adce6 258 SMART SM00086 87 128 0.0041 T 14-10-2018 IPR001610 PAC motif LH59_24235 4803f4b72b6c629e5a8f3b5e735adce6 258 SUPERFAMILY SSF46894 182 254 2.65E-16 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LH59_24235 4803f4b72b6c629e5a8f3b5e735adce6 258 SUPERFAMILY SSF55785 16 125 7.78E-21 T 14-10-2018 IPR035965 PAS domain superfamily LH59_24235 4803f4b72b6c629e5a8f3b5e735adce6 258 Pfam PF00196 Bacterial regulatory proteins, luxR family 194 247 2.5E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_24235 4803f4b72b6c629e5a8f3b5e735adce6 258 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 16 132 3.4E-20 T 14-10-2018 IPR000014 PAS domain LH59_24235 4803f4b72b6c629e5a8f3b5e735adce6 258 Pfam PF00989 PAS fold 15 125 1.8E-15 T 14-10-2018 IPR013767 PAS fold GO:0006355 LH59_24235 4803f4b72b6c629e5a8f3b5e735adce6 258 SMART SM00421 191 248 4.1E-15 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_24235 4803f4b72b6c629e5a8f3b5e735adce6 258 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 208 224 8.9E-6 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_24235 4803f4b72b6c629e5a8f3b5e735adce6 258 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 194 208 8.9E-6 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_24235 4803f4b72b6c629e5a8f3b5e735adce6 258 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 224 236 8.9E-6 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_24235 4803f4b72b6c629e5a8f3b5e735adce6 258 Gene3D G3DSA:1.10.10.10 193 254 1.0E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_24235 4803f4b72b6c629e5a8f3b5e735adce6 258 SMART SM00091 14 80 6.0E-9 T 14-10-2018 IPR000014 PAS domain LH59_12955 69e37887bf3ceba57c5dc1d8c0a60a32 233 SUPERFAMILY SSF52540 2 231 8.46E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_12955 69e37887bf3ceba57c5dc1d8c0a60a32 233 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_12955 69e37887bf3ceba57c5dc1d8c0a60a32 233 PIRSF PIRSF039137 1 233 3.8E-106 T 14-10-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 LH59_12955 69e37887bf3ceba57c5dc1d8c0a60a32 233 Gene3D G3DSA:3.40.50.300 1 233 3.2E-64 T 14-10-2018 LH59_12955 69e37887bf3ceba57c5dc1d8c0a60a32 233 Pfam PF00005 ABC transporter 17 161 1.0E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_12955 69e37887bf3ceba57c5dc1d8c0a60a32 233 SMART SM00382 26 212 5.5E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_06010 164de5c9c505670f0771d99132b022dd 656 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 14 495 5.5E-196 T 14-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 LH59_06010 164de5c9c505670f0771d99132b022dd 656 ProSitePatterns PS01303 BCCT family of transporters signature. 314 323 - T 14-10-2018 IPR018093 BCCT transporter, conserved site LH59_06010 164de5c9c505670f0771d99132b022dd 656 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 52 497 5.0E-159 T 14-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 LH59_08755 1c1810b095dcc78b17023b91c9a63bd2 382 Gene3D G3DSA:3.40.50.2000 25 181 1.8E-62 T 14-10-2018 LH59_08755 1c1810b095dcc78b17023b91c9a63bd2 382 Pfam PF13439 Glycosyltransferase Family 4 25 182 6.9E-13 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 LH59_08755 1c1810b095dcc78b17023b91c9a63bd2 382 Gene3D G3DSA:3.40.50.2000 182 340 1.8E-62 T 14-10-2018 LH59_08755 1c1810b095dcc78b17023b91c9a63bd2 382 SUPERFAMILY SSF53756 13 375 3.56E-56 T 14-10-2018 LH59_08755 1c1810b095dcc78b17023b91c9a63bd2 382 Pfam PF13692 Glycosyl transferases group 1 211 340 5.7E-19 T 14-10-2018 LH59_25050 bee23d652abebfbd57d48b2cea404943 401 SUPERFAMILY SSF54862 44 97 5.23E-6 T 14-10-2018 LH59_25050 bee23d652abebfbd57d48b2cea404943 401 TIGRFAM TIGR02484 CitB: CitB domain protein 40 394 2.1E-126 T 14-10-2018 IPR012830 Citrate utilization protein B LH59_25050 bee23d652abebfbd57d48b2cea404943 401 SUPERFAMILY SSF103501 180 392 1.02E-32 T 14-10-2018 IPR036197 NarG-like superfamily LH59_12255 2a3abc013da38852bf86443f3b7a21ed 160 PIRSF PIRSF019239 2 160 6.9E-37 T 14-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 LH59_12255 2a3abc013da38852bf86443f3b7a21ed 160 Pfam PF01899 Na+/H+ ion antiporter subunit 11 158 1.4E-40 T 14-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 LH59_07735 17b79915f0648fb33182003ecacca381 287 SUPERFAMILY SSF53850 90 283 3.51E-36 T 14-10-2018 LH59_07735 17b79915f0648fb33182003ecacca381 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.0E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_07735 17b79915f0648fb33182003ecacca381 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.0E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_07735 17b79915f0648fb33182003ecacca381 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.0E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_07735 17b79915f0648fb33182003ecacca381 287 Gene3D G3DSA:3.40.190.290 91 286 1.2E-36 T 14-10-2018 LH59_07735 17b79915f0648fb33182003ecacca381 287 SUPERFAMILY SSF46785 6 103 1.25E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_07735 17b79915f0648fb33182003ecacca381 287 TIGRFAM TIGR03339 phn_lysR: aminoethylphosphonate catabolism associated LysR family transcriptional regulator 5 283 5.3E-127 T 14-10-2018 IPR017724 Aminoethylphosphonate utilisation-associated transcription regulator, LysR-type LH59_07735 17b79915f0648fb33182003ecacca381 287 Pfam PF03466 LysR substrate binding domain 88 283 1.3E-35 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_07735 17b79915f0648fb33182003ecacca381 287 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 61 6.8E-21 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_07735 17b79915f0648fb33182003ecacca381 287 Gene3D G3DSA:1.10.10.10 1 90 1.0E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_26190 05bb5cf8813c128a8479ceb743bdb167 443 ProSitePatterns PS00217 Sugar transport proteins signature 2. 133 158 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 LH59_26190 05bb5cf8813c128a8479ceb743bdb167 443 ProSitePatterns PS00216 Sugar transport proteins signature 1. 305 321 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 LH59_26190 05bb5cf8813c128a8479ceb743bdb167 443 Gene3D G3DSA:1.20.1250.20 20 443 4.5E-61 T 14-10-2018 LH59_26190 05bb5cf8813c128a8479ceb743bdb167 443 Pfam PF07690 Major Facilitator Superfamily 32 310 3.0E-24 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_26190 05bb5cf8813c128a8479ceb743bdb167 443 SUPERFAMILY SSF103473 20 435 3.79E-66 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_27835 b0670e1affa2abf941146002cf3b4e82 390 Pfam PF13458 Periplasmic binding protein 25 362 2.4E-53 T 14-10-2018 IPR028081 Leucine-binding protein domain LH59_27835 b0670e1affa2abf941146002cf3b4e82 390 SUPERFAMILY SSF53822 24 385 3.3E-65 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_27835 b0670e1affa2abf941146002cf3b4e82 390 Gene3D G3DSA:3.40.50.2300 32 355 1.1E-122 T 14-10-2018 LH59_27835 b0670e1affa2abf941146002cf3b4e82 390 Gene3D G3DSA:3.40.50.2300 144 363 1.1E-122 T 14-10-2018 LH59_05605 9cc464d58fa0d329138710298c255b6b 597 Pfam PF00005 ABC transporter 367 515 1.5E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_05605 9cc464d58fa0d329138710298c255b6b 597 ProSitePatterns PS00211 ABC transporters family signature. 487 501 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_05605 9cc464d58fa0d329138710298c255b6b 597 Pfam PF00664 ABC transporter transmembrane region 31 296 1.2E-18 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 LH59_05605 9cc464d58fa0d329138710298c255b6b 597 SUPERFAMILY SSF90123 20 338 2.75E-47 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 LH59_05605 9cc464d58fa0d329138710298c255b6b 597 Gene3D G3DSA:3.40.50.300 347 590 3.7E-85 T 14-10-2018 LH59_05605 9cc464d58fa0d329138710298c255b6b 597 Gene3D G3DSA:1.20.1560.10 6 334 3.2E-42 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 LH59_05605 9cc464d58fa0d329138710298c255b6b 597 SMART SM00382 376 561 2.0E-18 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_05605 9cc464d58fa0d329138710298c255b6b 597 SUPERFAMILY SSF52540 343 583 4.05E-84 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_14460 e5dc1758f77bd568597b14b4c7343ccf 235 Pfam PF12697 Alpha/beta hydrolase family 1 229 5.7E-14 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_14460 e5dc1758f77bd568597b14b4c7343ccf 235 SUPERFAMILY SSF53474 1 232 8.93E-32 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_14460 e5dc1758f77bd568597b14b4c7343ccf 235 Gene3D G3DSA:3.40.50.1820 1 234 3.2E-44 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_03500 f4b5aca15aedc5cc8a55cb39e1638cce 300 Gene3D G3DSA:3.40.190.290 96 298 7.1E-35 T 14-10-2018 LH59_03500 f4b5aca15aedc5cc8a55cb39e1638cce 300 SUPERFAMILY SSF46785 5 114 1.36E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_03500 f4b5aca15aedc5cc8a55cb39e1638cce 300 SUPERFAMILY SSF53850 94 298 4.42E-39 T 14-10-2018 LH59_03500 f4b5aca15aedc5cc8a55cb39e1638cce 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 4.6E-12 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_03500 f4b5aca15aedc5cc8a55cb39e1638cce 300 Gene3D G3DSA:1.10.10.10 5 95 2.7E-12 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_03500 f4b5aca15aedc5cc8a55cb39e1638cce 300 Pfam PF03466 LysR substrate binding domain 92 294 1.6E-37 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_26505 1998f8a695b55b1c67d327c1e943f956 375 Gene3D G3DSA:3.40.50.450 2 299 7.0E-105 T 14-10-2018 LH59_26505 1998f8a695b55b1c67d327c1e943f956 375 Pfam PF02481 DNA recombination-mediator protein A 81 288 8.2E-75 T 14-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 LH59_26505 1998f8a695b55b1c67d327c1e943f956 375 Gene3D G3DSA:1.10.10.10 301 372 1.9E-11 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_26505 1998f8a695b55b1c67d327c1e943f956 375 SUPERFAMILY SSF102405 88 297 1.25E-41 T 14-10-2018 LH59_26505 1998f8a695b55b1c67d327c1e943f956 375 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 76 297 4.7E-74 T 14-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 LH59_00450 e8e1af3a0a568a0178a9dba47647d3c2 210 PIRSF PIRSF006324 1 209 4.5E-52 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 LH59_00450 e8e1af3a0a568a0178a9dba47647d3c2 210 Pfam PF01810 LysE type translocator 16 207 3.6E-35 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 LH59_22500 435183136af61a5a48deefc3c9d4eb05 374 Pfam PF04914 DltD protein 65 372 2.2E-41 T 14-10-2018 IPR006998 DltD LH59_24275 3813be54fb43a3ea8f8bf5b6f0ba5fff 322 Pfam PF04773 FecR protein 117 209 5.8E-19 T 14-10-2018 IPR006860 FecR protein LH59_24275 3813be54fb43a3ea8f8bf5b6f0ba5fff 322 Gene3D G3DSA:2.60.120.1440 104 245 7.5E-19 T 14-10-2018 LH59_24275 3813be54fb43a3ea8f8bf5b6f0ba5fff 322 PIRSF PIRSF018266 2 322 2.0E-82 T 14-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component LH59_24275 3813be54fb43a3ea8f8bf5b6f0ba5fff 322 Pfam PF16220 Domain of unknown function (DUF4880) 10 52 2.1E-11 T 14-10-2018 IPR032623 FecR, N-terminal LH59_04195 d61d5c4e749961ef865493efc4085bc3 265 Gene3D G3DSA:3.40.190.10 31 260 4.1E-102 T 14-10-2018 LH59_04195 d61d5c4e749961ef865493efc4085bc3 265 TIGRFAM TIGR00363 TIGR00363: lipoprotein, YaeC family 27 265 2.6E-77 T 14-10-2018 IPR004872 Lipoprotein NlpA family LH59_04195 d61d5c4e749961ef865493efc4085bc3 265 Gene3D G3DSA:3.40.190.10 111 216 4.1E-102 T 14-10-2018 LH59_04195 d61d5c4e749961ef865493efc4085bc3 265 SUPERFAMILY SSF53850 30 265 7.24E-92 T 14-10-2018 LH59_04195 d61d5c4e749961ef865493efc4085bc3 265 Pfam PF03180 NLPA lipoprotein 30 265 1.4E-97 T 14-10-2018 IPR004872 Lipoprotein NlpA family LH59_04195 d61d5c4e749961ef865493efc4085bc3 265 PIRSF PIRSF002854 1 265 3.3E-107 T 14-10-2018 IPR004872 Lipoprotein NlpA family LH59_24375 9d0ccab8ac1d120f05f7a27d273aad2b 439 SUPERFAMILY SSF51905 3 347 2.22E-31 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_24375 9d0ccab8ac1d120f05f7a27d273aad2b 439 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 12 341 2.4E-55 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LH59_24375 9d0ccab8ac1d120f05f7a27d273aad2b 439 Gene3D G3DSA:3.50.50.100 4 421 2.9E-103 T 14-10-2018 LH59_24375 9d0ccab8ac1d120f05f7a27d273aad2b 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 176 201 3.4E-8 T 14-10-2018 LH59_24375 9d0ccab8ac1d120f05f7a27d273aad2b 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 12 34 3.4E-8 T 14-10-2018 LH59_24375 9d0ccab8ac1d120f05f7a27d273aad2b 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 313 320 3.4E-8 T 14-10-2018 LH59_24375 9d0ccab8ac1d120f05f7a27d273aad2b 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 298 320 1.2E-19 T 14-10-2018 LH59_24375 9d0ccab8ac1d120f05f7a27d273aad2b 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 13 32 1.2E-19 T 14-10-2018 LH59_24375 9d0ccab8ac1d120f05f7a27d273aad2b 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 176 194 1.2E-19 T 14-10-2018 LH59_24375 9d0ccab8ac1d120f05f7a27d273aad2b 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 117 135 1.2E-19 T 14-10-2018 LH59_25145 994d08005dd831bd53c07f1a9329a8da 236 Pfam PF07729 FCD domain 90 216 5.3E-29 T 14-10-2018 IPR011711 GntR, C-terminal LH59_25145 994d08005dd831bd53c07f1a9329a8da 236 Gene3D G3DSA:1.10.10.10 5 80 6.1E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_25145 994d08005dd831bd53c07f1a9329a8da 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 80 2.4E-15 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_25145 994d08005dd831bd53c07f1a9329a8da 236 Gene3D G3DSA:1.20.120.530 85 230 2.6E-34 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_25145 994d08005dd831bd53c07f1a9329a8da 236 SMART SM00345 22 80 6.9E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_25145 994d08005dd831bd53c07f1a9329a8da 236 SUPERFAMILY SSF46785 13 109 1.24E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_25145 994d08005dd831bd53c07f1a9329a8da 236 SUPERFAMILY SSF48008 85 220 2.62E-28 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_25145 994d08005dd831bd53c07f1a9329a8da 236 SMART SM00895 90 217 1.1E-25 T 14-10-2018 IPR011711 GntR, C-terminal LH59_12280 2441d44b81f8fc8519cfa6f9c0b0a395 163 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 15 157 47.91 T 14-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 LH59_12280 2441d44b81f8fc8519cfa6f9c0b0a395 163 Pfam PF14437 MafB19-like deaminase 11 157 5.1E-30 T 14-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 LH59_12280 2441d44b81f8fc8519cfa6f9c0b0a395 163 Gene3D G3DSA:3.40.140.10 7 162 1.1E-58 T 14-10-2018 LH59_12280 2441d44b81f8fc8519cfa6f9c0b0a395 163 SUPERFAMILY SSF53927 5 157 3.97E-56 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 LH59_12280 2441d44b81f8fc8519cfa6f9c0b0a395 163 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 61 98 - T 14-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 LH59_18555 cb8cde4ccc9f762e8023b589b9524df0 218 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 39 213 6.2E-23 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_18555 cb8cde4ccc9f762e8023b589b9524df0 218 Gene3D G3DSA:1.10.3720.10 3 217 7.6E-52 T 14-10-2018 IPR035906 MetI-like superfamily LH59_18555 cb8cde4ccc9f762e8023b589b9524df0 218 SUPERFAMILY SSF161098 9 207 8.76E-46 T 14-10-2018 IPR035906 MetI-like superfamily LH59_07420 e7bb6bbb105e274dbd3147caf3376c3b 302 Gene3D G3DSA:3.40.50.620 8 211 4.5E-53 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LH59_07420 e7bb6bbb105e274dbd3147caf3376c3b 302 SUPERFAMILY SSF52402 7 210 3.31E-62 T 14-10-2018 LH59_07420 e7bb6bbb105e274dbd3147caf3376c3b 302 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 10 302 3.6E-125 T 14-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 LH59_07420 e7bb6bbb105e274dbd3147caf3376c3b 302 PIRSF PIRSF002936 1 302 3.7E-139 T 14-10-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 LH59_07420 e7bb6bbb105e274dbd3147caf3376c3b 302 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 31 255 9.2E-46 T 14-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 LH59_23580 26775a09819f015e5409099adc1c115d 698 SMART SM00052 434 677 2.0E-59 T 14-10-2018 IPR001633 EAL domain LH59_23580 26775a09819f015e5409099adc1c115d 698 SUPERFAMILY SSF141868 446 685 7.06E-61 T 14-10-2018 IPR035919 EAL domain superfamily LH59_23580 26775a09819f015e5409099adc1c115d 698 Pfam PF00563 EAL domain 446 671 1.2E-55 T 14-10-2018 IPR001633 EAL domain LH59_23580 26775a09819f015e5409099adc1c115d 698 Gene3D G3DSA:3.20.20.450 442 692 6.1E-67 T 14-10-2018 IPR035919 EAL domain superfamily LH59_23580 26775a09819f015e5409099adc1c115d 698 Pfam PF02378 Phosphotransferase system, EIIC 28 329 1.6E-20 T 14-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 LH59_00030 207211f17e860d4785819b716a8c6afd 530 Gene3D G3DSA:1.20.1250.20 14 402 8.3E-41 T 14-10-2018 LH59_00030 207211f17e860d4785819b716a8c6afd 530 Pfam PF05977 Transmembrane secretion effector 11 527 7.6E-209 T 14-10-2018 IPR010290 Transmembrane secretion effector LH59_00030 207211f17e860d4785819b716a8c6afd 530 SUPERFAMILY SSF103473 17 403 6.28E-49 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_19915 101aff7070690ce8c939189419457710 284 PRINTS PR00377 Inositol monophosphatase superfamily signature 222 246 1.9E-18 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 LH59_19915 101aff7070690ce8c939189419457710 284 PRINTS PR00377 Inositol monophosphatase superfamily signature 45 65 1.9E-18 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 LH59_19915 101aff7070690ce8c939189419457710 284 PRINTS PR00377 Inositol monophosphatase superfamily signature 94 110 1.9E-18 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 LH59_19915 101aff7070690ce8c939189419457710 284 PRINTS PR00377 Inositol monophosphatase superfamily signature 67 83 1.9E-18 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 LH59_19915 101aff7070690ce8c939189419457710 284 Gene3D G3DSA:3.40.190.80 174 281 8.8E-15 T 14-10-2018 LH59_19915 101aff7070690ce8c939189419457710 284 Pfam PF00459 Inositol monophosphatase family 17 262 8.2E-42 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 LH59_19915 101aff7070690ce8c939189419457710 284 Gene3D G3DSA:3.30.540.10 3 154 5.9E-36 T 14-10-2018 LH59_19915 101aff7070690ce8c939189419457710 284 SUPERFAMILY SSF56655 11 274 2.49E-58 T 14-10-2018 LH59_14845 b603ab3bd3b983d1a60b65c9d2f7f7cb 331 Gene3D G3DSA:3.40.190.10 130 254 4.2E-97 T 14-10-2018 LH59_14845 b603ab3bd3b983d1a60b65c9d2f7f7cb 331 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 308 1.2E-66 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_14845 b603ab3bd3b983d1a60b65c9d2f7f7cb 331 SUPERFAMILY SSF53850 109 289 4.45E-8 T 14-10-2018 LH59_14845 b603ab3bd3b983d1a60b65c9d2f7f7cb 331 PIRSF PIRSF017082 1 329 3.9E-72 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_14845 b603ab3bd3b983d1a60b65c9d2f7f7cb 331 Gene3D G3DSA:3.40.190.150 32 317 4.2E-97 T 14-10-2018 LH59_03370 6315effc41977e4a5a508a63c7bef98b 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 31.332 T 14-10-2018 IPR023035 Ribosomal protein S9, bacterial/plastid LH59_03370 6315effc41977e4a5a508a63c7bef98b 130 SUPERFAMILY SSF54211 5 130 3.79E-46 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold LH59_03370 6315effc41977e4a5a508a63c7bef98b 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 3.1E-45 T 14-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 LH59_03370 6315effc41977e4a5a508a63c7bef98b 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 14-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 LH59_03370 6315effc41977e4a5a508a63c7bef98b 130 Gene3D G3DSA:3.30.230.10 2 130 1.4E-50 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup LH59_26120 7d7ee1f3886bd22b008cfdf43bc62bc9 187 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 2 185 36.723 T 14-10-2018 IPR004507 Flavin prenyltransferase UbiX-like LH59_26120 7d7ee1f3886bd22b008cfdf43bc62bc9 187 SUPERFAMILY SSF52507 2 181 2.49E-61 T 14-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 LH59_26120 7d7ee1f3886bd22b008cfdf43bc62bc9 187 Gene3D G3DSA:3.40.50.1950 2 187 6.6E-74 T 14-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 LH59_26120 7d7ee1f3886bd22b008cfdf43bc62bc9 187 Pfam PF02441 Flavoprotein 3 165 9.3E-26 T 14-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 LH59_26120 7d7ee1f3886bd22b008cfdf43bc62bc9 187 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 3 179 1.0E-71 T 14-10-2018 IPR004507 Flavin prenyltransferase UbiX-like LH59_08855 6995d88706ab29fff91011e2b553a5c5 134 SUPERFAMILY SSF81301 1 109 5.4E-35 T 14-10-2018 LH59_08855 6995d88706ab29fff91011e2b553a5c5 134 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 8 104 1.2E-32 T 14-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS LH59_08855 6995d88706ab29fff91011e2b553a5c5 134 Pfam PF02410 Ribosomal silencing factor during starvation 9 104 1.3E-24 T 14-10-2018 LH59_08855 6995d88706ab29fff91011e2b553a5c5 134 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 3 105 23.607 T 14-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS LH59_08855 6995d88706ab29fff91011e2b553a5c5 134 Gene3D G3DSA:3.30.460.10 1 114 1.2E-32 T 14-10-2018 LH59_20200 89a303afd1063a16e3080198ec4ac79e 217 SMART SM00382 20 190 0.0024 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_20200 89a303afd1063a16e3080198ec4ac79e 217 SUPERFAMILY SSF52540 21 202 4.54E-24 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_20200 89a303afd1063a16e3080198ec4ac79e 217 Gene3D G3DSA:3.40.50.300 17 212 3.8E-25 T 14-10-2018 LH59_15765 91a28afc1f889694c6f1af7176a006fa 551 SUPERFAMILY SSF161098 5 264 3.55E-36 T 14-10-2018 IPR035906 MetI-like superfamily LH59_15765 91a28afc1f889694c6f1af7176a006fa 551 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 78 266 1.0E-13 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_15765 91a28afc1f889694c6f1af7176a006fa 551 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 367 545 4.3E-12 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_15765 91a28afc1f889694c6f1af7176a006fa 551 SUPERFAMILY SSF161098 289 547 3.74E-42 T 14-10-2018 IPR035906 MetI-like superfamily LH59_15765 91a28afc1f889694c6f1af7176a006fa 551 Gene3D G3DSA:1.10.3720.10 292 549 5.3E-43 T 14-10-2018 IPR035906 MetI-like superfamily LH59_15765 91a28afc1f889694c6f1af7176a006fa 551 Gene3D G3DSA:1.10.3720.10 4 272 1.9E-42 T 14-10-2018 IPR035906 MetI-like superfamily LH59_13255 ab55a05a61a33e06b2356ca747d8970d 237 Gene3D G3DSA:3.30.70.260 149 237 1.3E-5 T 14-10-2018 LH59_13255 ab55a05a61a33e06b2356ca747d8970d 237 PRINTS PR01837 MgtC/SapB protein signature 41 59 1.1E-39 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 LH59_13255 ab55a05a61a33e06b2356ca747d8970d 237 PRINTS PR01837 MgtC/SapB protein signature 22 41 1.1E-39 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 LH59_13255 ab55a05a61a33e06b2356ca747d8970d 237 PRINTS PR01837 MgtC/SapB protein signature 67 89 1.1E-39 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 LH59_13255 ab55a05a61a33e06b2356ca747d8970d 237 PRINTS PR01837 MgtC/SapB protein signature 94 118 1.1E-39 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 LH59_13255 ab55a05a61a33e06b2356ca747d8970d 237 Pfam PF02308 MgtC family 19 139 3.5E-33 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 LH59_18780 2f0c52c8afa95f1cb450204ae85f43bb 278 Pfam PF12146 Serine aminopeptidase, S33 68 161 2.6E-9 T 14-10-2018 IPR022742 Serine aminopeptidase, S33 LH59_18780 2f0c52c8afa95f1cb450204ae85f43bb 278 Pfam PF08386 TAP-like protein 188 271 1.3E-4 T 14-10-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal LH59_18780 2f0c52c8afa95f1cb450204ae85f43bb 278 Gene3D G3DSA:3.40.50.1820 52 260 1.2E-32 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_18780 2f0c52c8afa95f1cb450204ae85f43bb 278 SUPERFAMILY SSF53474 15 270 6.43E-38 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_17000 8350d746b6dc36d74d1ee9504ec3fe5c 701 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 65 699 3.3E-107 T 14-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 LH59_17000 8350d746b6dc36d74d1ee9504ec3fe5c 701 SUPERFAMILY SSF56935 22 700 9.77E-137 T 14-10-2018 LH59_17000 8350d746b6dc36d74d1ee9504ec3fe5c 701 Pfam PF07715 TonB-dependent Receptor Plug Domain 63 158 1.2E-22 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_17000 8350d746b6dc36d74d1ee9504ec3fe5c 701 Pfam PF00593 TonB dependent receptor 241 700 2.5E-59 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_17000 8350d746b6dc36d74d1ee9504ec3fe5c 701 Gene3D G3DSA:2.170.130.10 45 169 9.6E-41 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily LH59_17000 8350d746b6dc36d74d1ee9504ec3fe5c 701 Gene3D G3DSA:2.40.170.20 170 701 1.3E-122 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_14065 06bfe8fa24a2e8cbe9cc54d4e3b05010 266 TIGRFAM TIGR00245 TIGR00245: TIGR00245 family protein 8 251 6.0E-53 T 14-10-2018 IPR005226 UPF0014 family LH59_14065 06bfe8fa24a2e8cbe9cc54d4e3b05010 266 Pfam PF03649 Uncharacterised protein family (UPF0014) 9 250 1.3E-74 T 14-10-2018 IPR005226 UPF0014 family LH59_03225 6ec7d03f09bb561f86d2a5cf1b9485de 482 Gene3D G3DSA:3.30.300.30 368 479 1.6E-24 T 14-10-2018 LH59_03225 6ec7d03f09bb561f86d2a5cf1b9485de 482 ProSitePatterns PS00455 Putative AMP-binding domain signature. 128 139 - T 14-10-2018 IPR020845 AMP-binding, conserved site LH59_03225 6ec7d03f09bb561f86d2a5cf1b9485de 482 Gene3D G3DSA:3.40.50.12780 11 367 2.0E-99 T 14-10-2018 LH59_03225 6ec7d03f09bb561f86d2a5cf1b9485de 482 SUPERFAMILY SSF56801 14 479 1.24E-114 T 14-10-2018 LH59_03225 6ec7d03f09bb561f86d2a5cf1b9485de 482 Pfam PF00501 AMP-binding enzyme 119 374 1.5E-55 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 LH59_03225 6ec7d03f09bb561f86d2a5cf1b9485de 482 Pfam PF00501 AMP-binding enzyme 14 105 6.3E-16 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 LH59_09405 346e0aef19a6751dc02ca80dfe264ee4 721 SUPERFAMILY SSF52540 476 710 1.01E-72 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_09405 346e0aef19a6751dc02ca80dfe264ee4 721 Gene3D G3DSA:1.20.1560.10 159 470 5.9E-49 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 LH59_09405 346e0aef19a6751dc02ca80dfe264ee4 721 TIGRFAM TIGR03375 type_I_sec_LssB: type I secretion system ATPase 22 715 3.7E-299 T 14-10-2018 IPR017750 ATPase, type I secretion system LH59_09405 346e0aef19a6751dc02ca80dfe264ee4 721 Pfam PF00664 ABC transporter transmembrane region 175 432 4.4E-22 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 LH59_09405 346e0aef19a6751dc02ca80dfe264ee4 721 Gene3D G3DSA:3.90.70.10 17 143 1.1E-36 T 14-10-2018 LH59_09405 346e0aef19a6751dc02ca80dfe264ee4 721 SMART SM00382 512 698 8.7E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_09405 346e0aef19a6751dc02ca80dfe264ee4 721 SUPERFAMILY SSF90123 159 471 3.27E-52 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 LH59_09405 346e0aef19a6751dc02ca80dfe264ee4 721 Gene3D G3DSA:3.40.50.300 478 717 9.4E-77 T 14-10-2018 LH59_09405 346e0aef19a6751dc02ca80dfe264ee4 721 Pfam PF00005 ABC transporter 503 651 1.1E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_09405 346e0aef19a6751dc02ca80dfe264ee4 721 Pfam PF03412 Peptidase C39 family 21 141 5.7E-5 T 14-10-2018 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 LH59_27465 58a73eccaf0d8facfe984f597316b773 295 Pfam PF00892 EamA-like transporter family 150 281 2.2E-18 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_27465 58a73eccaf0d8facfe984f597316b773 295 Pfam PF00892 EamA-like transporter family 9 136 6.5E-23 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_27465 58a73eccaf0d8facfe984f597316b773 295 SUPERFAMILY SSF103481 38 139 2.48E-18 T 14-10-2018 LH59_27465 58a73eccaf0d8facfe984f597316b773 295 SUPERFAMILY SSF103481 185 281 6.8E-13 T 14-10-2018 LH59_26850 db66cc346c47137c5f2f619ffed1e0f9 235 SUPERFAMILY SSF46785 149 222 2.53E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_26850 db66cc346c47137c5f2f619ffed1e0f9 235 Gene3D G3DSA:1.10.10.10 155 224 2.3E-11 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_26850 db66cc346c47137c5f2f619ffed1e0f9 235 Pfam PF00027 Cyclic nucleotide-binding domain 32 118 6.4E-12 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain LH59_26850 db66cc346c47137c5f2f619ffed1e0f9 235 SMART SM00100 13 134 3.0E-4 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain LH59_26850 db66cc346c47137c5f2f619ffed1e0f9 235 Gene3D G3DSA:2.60.120.10 5 154 3.3E-18 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_26850 db66cc346c47137c5f2f619ffed1e0f9 235 Pfam PF13545 Crp-like helix-turn-helix domain 151 220 3.1E-10 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 LH59_26850 db66cc346c47137c5f2f619ffed1e0f9 235 SUPERFAMILY SSF51206 12 140 8.77E-23 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like LH59_04720 3f11bf0e6ee0bdcce53a13f6b3c151be 375 Pfam PF07690 Major Facilitator Superfamily 18 327 1.5E-28 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_04720 3f11bf0e6ee0bdcce53a13f6b3c151be 375 SUPERFAMILY SSF103473 18 361 1.23E-38 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_04720 3f11bf0e6ee0bdcce53a13f6b3c151be 375 PRINTS PR01035 Tetracycline resistance protein signature 28 47 8.3E-6 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 LH59_04720 3f11bf0e6ee0bdcce53a13f6b3c151be 375 PRINTS PR01035 Tetracycline resistance protein signature 116 138 8.3E-6 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 LH59_04720 3f11bf0e6ee0bdcce53a13f6b3c151be 375 PRINTS PR01035 Tetracycline resistance protein signature 230 250 8.3E-6 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 LH59_04720 3f11bf0e6ee0bdcce53a13f6b3c151be 375 PRINTS PR01035 Tetracycline resistance protein signature 318 341 8.3E-6 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 LH59_04720 3f11bf0e6ee0bdcce53a13f6b3c151be 375 Gene3D G3DSA:1.20.1250.20 5 363 3.3E-36 T 14-10-2018 LH59_22390 c3c35a1078b4f3a3af21a5fd4a9a139a 371 PIRSF PIRSF007313 1 363 1.8E-154 T 14-10-2018 IPR008773 Phosphonate metabolism protein PhnI GO:0019634 LH59_22390 c3c35a1078b4f3a3af21a5fd4a9a139a 371 Pfam PF05861 Bacterial phosphonate metabolism protein (PhnI) 1 353 1.0E-160 T 14-10-2018 IPR008773 Phosphonate metabolism protein PhnI GO:0019634 LH59_03255 00ca4240ed6df4dbbd93cc0b48a25da7 1168 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 731 918 6.3E-20 T 14-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 LH59_03255 00ca4240ed6df4dbbd93cc0b48a25da7 1168 SUPERFAMILY SSF53323 723 942 4.32E-24 T 14-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 LH59_03255 00ca4240ed6df4dbbd93cc0b48a25da7 1168 SUPERFAMILY SSF52518 27 230 7.06E-15 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold LH59_03255 00ca4240ed6df4dbbd93cc0b48a25da7 1168 Gene3D G3DSA:3.40.920.10 720 923 7.4E-17 T 14-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 LH59_03255 00ca4240ed6df4dbbd93cc0b48a25da7 1168 SUPERFAMILY SSF52518 435 616 4.71E-10 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold LH59_03255 00ca4240ed6df4dbbd93cc0b48a25da7 1168 Gene3D G3DSA:3.40.50.970 16 227 2.8E-23 T 14-10-2018 LH59_03255 00ca4240ed6df4dbbd93cc0b48a25da7 1168 SUPERFAMILY SSF52922 282 372 4.71E-7 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 LH59_06210 17ec93e27ecacc8c78029387231e3ec6 172 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 109 158 2.3E-9 T 14-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 LH59_06210 17ec93e27ecacc8c78029387231e3ec6 172 Pfam PF02627 Carboxymuconolactone decarboxylase family 95 169 3.8E-12 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 LH59_06210 17ec93e27ecacc8c78029387231e3ec6 172 Gene3D G3DSA:1.20.1290.10 3 172 2.1E-51 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 LH59_06210 17ec93e27ecacc8c78029387231e3ec6 172 SUPERFAMILY SSF69118 4 169 7.92E-39 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 LH59_06210 17ec93e27ecacc8c78029387231e3ec6 172 Hamap MF_01676 Alkyl hydroperoxide reductase AhpD [ahpD]. 1 172 72.02 T 14-10-2018 IPR004674 Alkylhydroperoxidase AhpD GO:0006979|GO:0032843|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 LH59_03675 bf43f6e063c021aec4c95481da2b22d6 216 Pfam PF07729 FCD domain 82 196 1.1E-16 T 14-10-2018 IPR011711 GntR, C-terminal LH59_03675 bf43f6e063c021aec4c95481da2b22d6 216 Gene3D G3DSA:1.20.120.530 78 208 2.2E-17 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_03675 bf43f6e063c021aec4c95481da2b22d6 216 SMART SM00895 82 205 2.6E-10 T 14-10-2018 IPR011711 GntR, C-terminal LH59_03675 bf43f6e063c021aec4c95481da2b22d6 216 SUPERFAMILY SSF46785 5 76 1.9E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_03675 bf43f6e063c021aec4c95481da2b22d6 216 Gene3D G3DSA:1.10.10.10 1 73 3.9E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_03675 bf43f6e063c021aec4c95481da2b22d6 216 SMART SM00345 14 72 1.3E-10 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_03675 bf43f6e063c021aec4c95481da2b22d6 216 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 72 3.0E-12 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_03675 bf43f6e063c021aec4c95481da2b22d6 216 SUPERFAMILY SSF48008 79 207 9.94E-15 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_05875 a4b91835e530c394092058e61587535f 446 Pfam PF03600 Citrate transporter 14 387 9.2E-55 T 14-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 LH59_05875 a4b91835e530c394092058e61587535f 446 TIGRFAM TIGR00784 citMHS: citrate transporter 2 438 9.0E-187 T 14-10-2018 IPR014738 Citrate transporter GO:0015137|GO:0015746 LH59_02635 5a093695118d3f62830133c7490ad6f7 237 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_02635 5a093695118d3f62830133c7490ad6f7 237 Gene3D G3DSA:3.40.50.300 1 224 2.4E-63 T 14-10-2018 LH59_02635 5a093695118d3f62830133c7490ad6f7 237 SUPERFAMILY SSF52540 1 220 1.33E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_02635 5a093695118d3f62830133c7490ad6f7 237 Pfam PF00005 ABC transporter 18 166 7.8E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_02635 5a093695118d3f62830133c7490ad6f7 237 SMART SM00382 27 214 2.6E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_20950 55ab4883d7687b3d44882ef5e90701f6 175 Pfam PF09335 SNARE associated Golgi protein 44 167 7.2E-12 T 14-10-2018 IPR032816 SNARE associated Golgi protein LH59_19370 a22399d3de9252b87e4798a151547139 400 SMART SM00155 111 138 4.5E-5 T 14-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 LH59_19370 a22399d3de9252b87e4798a151547139 400 SMART SM00155 284 311 19.0 T 14-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 LH59_19370 a22399d3de9252b87e4798a151547139 400 Pfam PF13091 PLD-like domain 31 161 3.6E-13 T 14-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 LH59_19370 a22399d3de9252b87e4798a151547139 400 Pfam PF13091 PLD-like domain 215 338 2.7E-23 T 14-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 LH59_19370 a22399d3de9252b87e4798a151547139 400 Hamap MF_01917 Cardiolipin synthase B [clsB]. 5 382 49.082 T 14-10-2018 IPR030872 Cardiolipin synthase B GO:0008808|GO:0032049 LH59_19370 a22399d3de9252b87e4798a151547139 400 Gene3D G3DSA:3.30.870.10 2 180 4.7E-34 T 14-10-2018 LH59_19370 a22399d3de9252b87e4798a151547139 400 SUPERFAMILY SSF56024 187 344 8.07E-33 T 14-10-2018 LH59_19370 a22399d3de9252b87e4798a151547139 400 SUPERFAMILY SSF56024 7 168 1.1E-37 T 14-10-2018 LH59_19370 a22399d3de9252b87e4798a151547139 400 Gene3D G3DSA:3.30.870.10 195 365 5.9E-22 T 14-10-2018 LH59_24590 793de306c8f962369e6348c06f4c8252 305 Gene3D G3DSA:3.40.190.10 172 269 1.8E-59 T 14-10-2018 LH59_24590 793de306c8f962369e6348c06f4c8252 305 Gene3D G3DSA:1.10.10.10 1 90 2.7E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_24590 793de306c8f962369e6348c06f4c8252 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 68 1.4E-15 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_24590 793de306c8f962369e6348c06f4c8252 305 SUPERFAMILY SSF46785 5 87 1.01E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_24590 793de306c8f962369e6348c06f4c8252 305 SUPERFAMILY SSF53850 91 296 4.34E-33 T 14-10-2018 LH59_24590 793de306c8f962369e6348c06f4c8252 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 24 35 1.7E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_24590 793de306c8f962369e6348c06f4c8252 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 35 45 1.7E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_24590 793de306c8f962369e6348c06f4c8252 305 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 45 56 1.7E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_24590 793de306c8f962369e6348c06f4c8252 305 Gene3D G3DSA:3.40.190.10 94 293 1.8E-59 T 14-10-2018 LH59_24590 793de306c8f962369e6348c06f4c8252 305 Pfam PF03466 LysR substrate binding domain 96 298 2.3E-15 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_15715 e383fdc208333baff8a27d6fd1fb92dc 385 Gene3D G3DSA:3.50.50.60 6 382 4.2E-141 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_15715 e383fdc208333baff8a27d6fd1fb92dc 385 SUPERFAMILY SSF54373 177 278 4.32E-8 T 14-10-2018 LH59_15715 e383fdc208333baff8a27d6fd1fb92dc 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 286 301 2.2E-19 T 14-10-2018 LH59_15715 e383fdc208333baff8a27d6fd1fb92dc 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 151 166 2.2E-19 T 14-10-2018 LH59_15715 e383fdc208333baff8a27d6fd1fb92dc 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 301 317 2.2E-19 T 14-10-2018 LH59_15715 e383fdc208333baff8a27d6fd1fb92dc 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 336 352 2.2E-19 T 14-10-2018 LH59_15715 e383fdc208333baff8a27d6fd1fb92dc 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 2.2E-19 T 14-10-2018 LH59_15715 e383fdc208333baff8a27d6fd1fb92dc 385 Pfam PF01494 FAD binding domain 7 348 7.7E-24 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 LH59_15715 e383fdc208333baff8a27d6fd1fb92dc 385 SUPERFAMILY SSF51905 5 372 1.44E-60 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_19880 f843cfd0219a08bb3b7b00d3b985a8db 221 SUPERFAMILY SSF50199 70 208 1.07E-34 T 14-10-2018 LH59_19880 f843cfd0219a08bb3b7b00d3b985a8db 221 SMART SM00318 69 201 9.7E-28 T 14-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 LH59_19880 f843cfd0219a08bb3b7b00d3b985a8db 221 Gene3D G3DSA:2.40.50.90 68 214 7.5E-32 T 14-10-2018 IPR035437 SNase-like, OB-fold superfamily LH59_19880 f843cfd0219a08bb3b7b00d3b985a8db 221 Pfam PF00565 Staphylococcal nuclease homologue 94 200 8.4E-18 T 14-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 LH59_19880 f843cfd0219a08bb3b7b00d3b985a8db 221 ProSitePatterns PS01123 Thermonuclease family signature 1. 80 104 - T 14-10-2018 IPR002071 Thermonuclease active site GO:0003676|GO:0004518 Reactome: R-HSA-6802952 LH59_05190 187a385ce871d4696f7fa75de025118f 251 Gene3D G3DSA:2.30.210.20 4 60 7.1E-24 T 14-10-2018 LH59_05190 187a385ce871d4696f7fa75de025118f 251 Gene3D G3DSA:3.40.630.70 61 242 3.2E-61 T 14-10-2018 LH59_05190 187a385ce871d4696f7fa75de025118f 251 Hamap MF_00688 Leucyl/phenylalanyl-tRNA--protein transferase [aat]. 1 251 96.133 T 14-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 LH59_05190 187a385ce871d4696f7fa75de025118f 251 Pfam PF03588 Leucyl/phenylalanyl-tRNA protein transferase 35 213 3.0E-70 T 14-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 LH59_05190 187a385ce871d4696f7fa75de025118f 251 SUPERFAMILY SSF55729 3 233 2.44E-86 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_05190 187a385ce871d4696f7fa75de025118f 251 TIGRFAM TIGR00667 aat: leucyl/phenylalanyl-tRNA--protein transferase 32 225 7.0E-54 T 14-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 LH59_18935 72a77fbb0a7dbd38803244453e869fa3 538 Gene3D G3DSA:2.40.160.50 159 538 2.7E-68 T 14-10-2018 LH59_18935 72a77fbb0a7dbd38803244453e869fa3 538 Pfam PF08479 POTRA domain, ShlB-type 46 119 2.8E-16 T 14-10-2018 IPR013686 Polypeptide-transport-associated, ShlB-type LH59_18935 72a77fbb0a7dbd38803244453e869fa3 538 Pfam PF03865 Haemolysin secretion/activation protein ShlB/FhaC/HecB 182 500 6.8E-20 T 14-10-2018 IPR005565 Haemolysin activator HlyB, C-terminal LH59_18935 72a77fbb0a7dbd38803244453e869fa3 538 Gene3D G3DSA:3.10.20.310 35 119 1.8E-14 T 14-10-2018 LH59_15585 15d8df78b315432d963ec97f83256e5b 213 SUPERFAMILY SSF52833 2 87 1.05E-20 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_15585 15d8df78b315432d963ec97f83256e5b 213 Pfam PF00043 Glutathione S-transferase, C-terminal domain 122 202 3.6E-8 T 14-10-2018 IPR004046 Glutathione S-transferase, C-terminal LH59_15585 15d8df78b315432d963ec97f83256e5b 213 Pfam PF13417 Glutathione S-transferase, N-terminal domain 7 79 6.0E-14 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 LH59_15585 15d8df78b315432d963ec97f83256e5b 213 Gene3D G3DSA:3.40.30.10 1 81 3.1E-32 T 14-10-2018 LH59_15585 15d8df78b315432d963ec97f83256e5b 213 SUPERFAMILY SSF47616 81 207 8.91E-29 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily LH59_15585 15d8df78b315432d963ec97f83256e5b 213 Gene3D G3DSA:1.20.1050.10 87 208 2.7E-43 T 14-10-2018 LH59_13725 8c45ecd8ee2041110bd8fdadc8c5346d 176 SUPERFAMILY SSF46785 3 145 1.21E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_13725 8c45ecd8ee2041110bd8fdadc8c5346d 176 Pfam PF12802 MarR family 26 80 1.6E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_13725 8c45ecd8ee2041110bd8fdadc8c5346d 176 PIRSF PIRSF006707 1 176 1.9E-55 T 14-10-2018 IPR026282 DNA-binding protein, MJ1563 type LH59_13725 8c45ecd8ee2041110bd8fdadc8c5346d 176 Gene3D G3DSA:1.10.10.10 1 86 4.0E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_10265 a9a03457e8ba46649289e9f79b8da651 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 2.3E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10265 a9a03457e8ba46649289e9f79b8da651 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 2.3E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10265 a9a03457e8ba46649289e9f79b8da651 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 2.3E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10265 a9a03457e8ba46649289e9f79b8da651 262 SUPERFAMILY SSF51735 6 249 4.24E-66 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_10265 a9a03457e8ba46649289e9f79b8da651 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 246 3.0E-56 T 14-10-2018 LH59_10265 a9a03457e8ba46649289e9f79b8da651 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 2.3E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10265 a9a03457e8ba46649289e9f79b8da651 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 2.3E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10265 a9a03457e8ba46649289e9f79b8da651 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 2.3E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10265 a9a03457e8ba46649289e9f79b8da651 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.3E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10265 a9a03457e8ba46649289e9f79b8da651 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 2.3E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10265 a9a03457e8ba46649289e9f79b8da651 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 2.3E-31 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10265 a9a03457e8ba46649289e9f79b8da651 262 Gene3D G3DSA:3.40.50.720 1 253 3.4E-65 T 14-10-2018 LH59_10265 a9a03457e8ba46649289e9f79b8da651 262 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LH59_21325 56fc9010aacb37e49a3257c946ff4eb0 513 Gene3D G3DSA:3.30.300.310 412 513 4.4E-32 T 14-10-2018 LH59_21325 56fc9010aacb37e49a3257c946ff4eb0 513 ProSitePatterns PS00455 Putative AMP-binding domain signature. 162 173 - T 14-10-2018 IPR020845 AMP-binding, conserved site LH59_21325 56fc9010aacb37e49a3257c946ff4eb0 513 Pfam PF00501 AMP-binding enzyme 21 416 4.4E-93 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 LH59_21325 56fc9010aacb37e49a3257c946ff4eb0 513 Pfam PF13193 AMP-binding enzyme C-terminal domain 425 500 4.3E-18 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain LH59_21325 56fc9010aacb37e49a3257c946ff4eb0 513 SUPERFAMILY SSF56801 6 512 8.11E-142 T 14-10-2018 LH59_21325 56fc9010aacb37e49a3257c946ff4eb0 513 Gene3D G3DSA:3.40.50.12780 14 409 9.8E-124 T 14-10-2018 LH59_14280 99e820966fc4a0bbacf27bf8709eabcf 245 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 30 133 9.1E-16 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 LH59_14280 99e820966fc4a0bbacf27bf8709eabcf 245 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 51 239 3.0E-14 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_14280 99e820966fc4a0bbacf27bf8709eabcf 245 SUPERFAMILY SSF161098 32 224 2.49E-31 T 14-10-2018 IPR035906 MetI-like superfamily LH59_14280 99e820966fc4a0bbacf27bf8709eabcf 245 Gene3D G3DSA:1.10.3720.10 27 240 4.3E-40 T 14-10-2018 IPR035906 MetI-like superfamily LH59_07060 35b2644b7314b3fe437f69a8d478863e 545 SUPERFAMILY SSF53474 171 474 1.66E-39 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_07060 35b2644b7314b3fe437f69a8d478863e 545 Pfam PF07167 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus 48 213 1.5E-62 T 14-10-2018 IPR010941 Poly-beta-hydroxybutyrate polymerase, N-terminal domain GO:0042619 LH59_07060 35b2644b7314b3fe437f69a8d478863e 545 Gene3D G3DSA:3.40.50.1820 187 466 2.3E-11 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_07060 35b2644b7314b3fe437f69a8d478863e 545 TIGRFAM TIGR01838 PHA_synth_I: poly(R)-hydroxyalkanoic acid synthase, class I 17 542 4.8E-198 T 14-10-2018 IPR010963 Poly(R)-hydroxyalkanoic acid synthase, class I GO:0005737|GO:0016746|GO:0042619 LH59_00415 ec0967020c4cac82f9e4b6a248c7d3ea 308 SUPERFAMILY SSF52317 1 183 3.06E-42 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_00415 ec0967020c4cac82f9e4b6a248c7d3ea 308 Gene3D G3DSA:1.10.10.60 203 307 5.5E-26 T 14-10-2018 LH59_00415 ec0967020c4cac82f9e4b6a248c7d3ea 308 Pfam PF01965 DJ-1/PfpI family 2 164 3.5E-19 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 LH59_00415 ec0967020c4cac82f9e4b6a248c7d3ea 308 Gene3D G3DSA:3.40.50.880 1 202 2.9E-52 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_00415 ec0967020c4cac82f9e4b6a248c7d3ea 308 SUPERFAMILY SSF46689 255 305 6.72E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_00415 ec0967020c4cac82f9e4b6a248c7d3ea 308 SUPERFAMILY SSF46689 205 252 1.25E-8 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_00415 ec0967020c4cac82f9e4b6a248c7d3ea 308 SMART SM00342 218 301 7.6E-23 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_00415 ec0967020c4cac82f9e4b6a248c7d3ea 308 Pfam PF12833 Helix-turn-helix domain 224 302 3.1E-21 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_00210 6dc49d4b2b4791822a340e04abc57593 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 293 315 6.4E-14 T 14-10-2018 LH59_00210 6dc49d4b2b4791822a340e04abc57593 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 117 135 6.4E-14 T 14-10-2018 LH59_00210 6dc49d4b2b4791822a340e04abc57593 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 6.4E-14 T 14-10-2018 LH59_00210 6dc49d4b2b4791822a340e04abc57593 481 Pfam PF04324 BFD-like [2Fe-2S] binding domain 385 437 9.4E-9 T 14-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain LH59_00210 6dc49d4b2b4791822a340e04abc57593 481 Gene3D G3DSA:3.50.50.60 129 269 1.9E-36 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_00210 6dc49d4b2b4791822a340e04abc57593 481 Gene3D G3DSA:3.50.50.60 8 318 1.9E-36 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_00210 6dc49d4b2b4791822a340e04abc57593 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 8 30 2.1E-11 T 14-10-2018 LH59_00210 6dc49d4b2b4791822a340e04abc57593 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 161 186 2.1E-11 T 14-10-2018 LH59_00210 6dc49d4b2b4791822a340e04abc57593 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 120 129 2.1E-11 T 14-10-2018 LH59_00210 6dc49d4b2b4791822a340e04abc57593 481 PIRSF PIRSF037495 1 475 8.4E-164 T 14-10-2018 IPR017224 Opine oxidase, subunit A/hydrogen cyanide synthase, subunit B GO:0016491|GO:0055114 LH59_00210 6dc49d4b2b4791822a340e04abc57593 481 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 330 1.4E-17 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LH59_00210 6dc49d4b2b4791822a340e04abc57593 481 Gene3D G3DSA:1.10.10.1100 375 446 7.0E-22 T 14-10-2018 LH59_00210 6dc49d4b2b4791822a340e04abc57593 481 SUPERFAMILY SSF51905 1 340 2.13E-32 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_02785 8a47c1e7436d183c300285403754d5df 215 Pfam PF01121 Dephospho-CoA kinase 4 178 1.4E-53 T 14-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 LH59_02785 8a47c1e7436d183c300285403754d5df 215 SUPERFAMILY SSF52540 1 198 4.49E-36 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_02785 8a47c1e7436d183c300285403754d5df 215 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 179 7.0E-41 T 14-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 LH59_02785 8a47c1e7436d183c300285403754d5df 215 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 195 25.476 T 14-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 LH59_02785 8a47c1e7436d183c300285403754d5df 215 Gene3D G3DSA:3.40.50.300 1 210 2.0E-59 T 14-10-2018 LH59_26770 368cdc985b9e3cc45058f024e7be9210 513 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 16 502 93.255 T 14-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_26770 368cdc985b9e3cc45058f024e7be9210 513 SUPERFAMILY SSF75304 12 508 1.96E-149 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_26770 368cdc985b9e3cc45058f024e7be9210 513 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 17 501 1.3E-160 T 14-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_26770 368cdc985b9e3cc45058f024e7be9210 513 Gene3D G3DSA:3.90.1300.10 11 511 3.0E-184 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_26770 368cdc985b9e3cc45058f024e7be9210 513 ProSitePatterns PS00571 Amidases signature. 155 186 - T 14-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 LH59_26770 368cdc985b9e3cc45058f024e7be9210 513 Pfam PF01425 Amidase 32 491 3.3E-141 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_01075 6f8e828249c027670f4ebafbf6b31d38 445 Gene3D G3DSA:1.10.4160.10 14 436 8.4E-8 T 14-10-2018 IPR038271 Purine-cytosine permease superfamily LH59_07110 327a933386b625886b7032d2e1eee198 112 SMART SM00749 44 107 8.2E-5 T 14-10-2018 IPR014004 Transport-associated and nodulation domain, bacteria LH59_07110 327a933386b625886b7032d2e1eee198 112 Pfam PF04972 BON domain 39 106 1.9E-18 T 14-10-2018 IPR007055 BON domain LH59_02235 da8206f0df7df12251e93a0fe680164d 299 SMART SM00849 67 274 3.8E-19 T 14-10-2018 IPR001279 Metallo-beta-lactamase LH59_02235 da8206f0df7df12251e93a0fe680164d 299 SUPERFAMILY SSF56281 12 297 2.36E-46 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like LH59_02235 da8206f0df7df12251e93a0fe680164d 299 Gene3D G3DSA:3.60.15.10 9 299 1.8E-76 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like LH59_02235 da8206f0df7df12251e93a0fe680164d 299 Pfam PF00753 Metallo-beta-lactamase superfamily 68 261 2.7E-21 T 14-10-2018 IPR001279 Metallo-beta-lactamase LH59_24370 96edfc1f49fd10fa9ff6654eaf89d293 132 Pfam PF01219 Prokaryotic diacylglycerol kinase 24 123 2.7E-32 T 14-10-2018 IPR000829 DAGK family GO:0008654|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 LH59_24370 96edfc1f49fd10fa9ff6654eaf89d293 132 Gene3D G3DSA:1.10.3830.10 11 130 2.6E-35 T 14-10-2018 IPR036945 Diacylglycerol kinase (DAGK) superfamily GO:0008610|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 LH59_02085 d686c79d375ab5c691542a0828503cdf 306 Gene3D G3DSA:3.40.50.300 12 291 1.1E-95 T 14-10-2018 LH59_02085 d686c79d375ab5c691542a0828503cdf 306 SUPERFAMILY SSF52540 82 271 3.25E-31 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_02085 d686c79d375ab5c691542a0828503cdf 306 TIGRFAM TIGR03707 PPK2_P_aer: polyphosphate kinase 2 52 277 2.0E-114 T 14-10-2018 IPR022486 Polyphosphate kinase 2, PA0141 GO:0006793|GO:0008976 KEGG: 00190+2.7.4.1 LH59_02085 d686c79d375ab5c691542a0828503cdf 306 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 53 276 7.4E-112 T 14-10-2018 IPR022488 Polyphosphate kinase-2-related LH59_02085 d686c79d375ab5c691542a0828503cdf 306 PIRSF PIRSF028756 17 306 4.0E-135 T 14-10-2018 IPR016898 Polyphosphate kinase 2 KEGG: 00190+2.7.4.1 LH59_08125 8db94591dd41c8a650546c5bef7841ae 469 Pfam PF14821 Threonine synthase N terminus 2 79 3.8E-29 T 14-10-2018 IPR029144 Threonine synthase, N-terminal LH59_08125 8db94591dd41c8a650546c5bef7841ae 469 Gene3D G3DSA:3.40.50.1100 109 448 1.2E-134 T 14-10-2018 LH59_08125 8db94591dd41c8a650546c5bef7841ae 469 Gene3D G3DSA:3.40.50.1100 97 435 1.2E-134 T 14-10-2018 LH59_08125 8db94591dd41c8a650546c5bef7841ae 469 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 105 407 2.0E-10 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme LH59_08125 8db94591dd41c8a650546c5bef7841ae 469 Gene3D G3DSA:3.90.1380.10 1 90 2.8E-30 T 14-10-2018 IPR037158 Threonine synthase, N-terminal domain superfamily LH59_08125 8db94591dd41c8a650546c5bef7841ae 469 TIGRFAM TIGR00260 thrC: threonine synthase 98 430 1.2E-72 T 14-10-2018 IPR004450 Threonine synthase-like LH59_08125 8db94591dd41c8a650546c5bef7841ae 469 SUPERFAMILY SSF53686 1 466 3.6E-154 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme LH59_10390 b2f96a836d16a9689c60727eef63d2a0 146 Gene3D G3DSA:3.40.470.10 1 145 1.9E-44 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 LH59_10390 b2f96a836d16a9689c60727eef63d2a0 146 SUPERFAMILY SSF52141 1 142 1.83E-28 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 LH59_10390 b2f96a836d16a9689c60727eef63d2a0 146 TIGRFAM TIGR04274 hypoxanDNAglyco: DNA-deoxyinosine glycosylase 1 138 4.5E-40 T 14-10-2018 IPR026353 Hypoxanthine-DNA glycosylase LH59_05110 371d81fe621b229ca1c6c09e3400da35 306 Gene3D G3DSA:3.20.10.10 133 295 8.2E-50 T 14-10-2018 LH59_05110 371d81fe621b229ca1c6c09e3400da35 306 SUPERFAMILY SSF56752 1 303 4.45E-99 T 14-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 LH59_05110 371d81fe621b229ca1c6c09e3400da35 306 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 11 306 3.3E-133 T 14-10-2018 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767 LH59_05110 371d81fe621b229ca1c6c09e3400da35 306 Gene3D G3DSA:3.30.470.10 7 132 1.2E-40 T 14-10-2018 LH59_05110 371d81fe621b229ca1c6c09e3400da35 306 Pfam PF01063 Amino-transferase class IV 37 267 1.4E-51 T 14-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 LH59_12845 fe22a987160a51113c06308b4287e2cb 386 Gene3D G3DSA:3.30.1950.10 87 170 4.5E-61 T 14-10-2018 LH59_12845 fe22a987160a51113c06308b4287e2cb 386 Gene3D G3DSA:3.10.560.10 70 252 4.5E-61 T 14-10-2018 LH59_12845 fe22a987160a51113c06308b4287e2cb 386 Gene3D G3DSA:3.10.560.10 253 343 4.5E-61 T 14-10-2018 LH59_12845 fe22a987160a51113c06308b4287e2cb 386 Pfam PF02563 Polysaccharide biosynthesis/export protein 85 164 4.0E-11 T 14-10-2018 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 LH59_25480 e18559beae8e58abc842e566290ef8d4 382 SUPERFAMILY SSF54826 1 112 1.45E-30 T 14-10-2018 LH59_25480 e18559beae8e58abc842e566290ef8d4 382 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 82 107 - T 14-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 LH59_25480 e18559beae8e58abc842e566290ef8d4 382 Pfam PF13378 Enolase C-terminal domain-like 130 355 9.8E-62 T 14-10-2018 IPR029065 Enolase C-terminal domain-like LH59_25480 e18559beae8e58abc842e566290ef8d4 382 SUPERFAMILY SSF51604 95 361 1.97E-79 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily LH59_25480 e18559beae8e58abc842e566290ef8d4 382 SMART SM00922 125 230 2.5E-22 T 14-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal LH59_25480 e18559beae8e58abc842e566290ef8d4 382 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 180 211 - T 14-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 LH59_25480 e18559beae8e58abc842e566290ef8d4 382 Gene3D G3DSA:3.30.390.10 11 374 1.1E-146 T 14-10-2018 IPR029017 Enolase-like, N-terminal LH59_25480 e18559beae8e58abc842e566290ef8d4 382 Gene3D G3DSA:3.20.20.120 102 344 1.1E-146 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily LH59_25480 e18559beae8e58abc842e566290ef8d4 382 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 15 107 9.0E-26 T 14-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain LH59_24465 75471db8eda0981a749b626c3995b257 167 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 2 158 35.393 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 LH59_24465 75471db8eda0981a749b626c3995b257 167 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 58 4.7E-15 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 LH59_24465 75471db8eda0981a749b626c3995b257 167 SUPERFAMILY SSF52374 1 156 1.41E-43 T 14-10-2018 LH59_24465 75471db8eda0981a749b626c3995b257 167 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 3 156 2.2E-56 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 LH59_24465 75471db8eda0981a749b626c3995b257 167 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 85 101 3.6E-48 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 LH59_24465 75471db8eda0981a749b626c3995b257 167 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 112 134 3.6E-48 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 LH59_24465 75471db8eda0981a749b626c3995b257 167 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 2 20 3.6E-48 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 LH59_24465 75471db8eda0981a749b626c3995b257 167 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 20 41 3.6E-48 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 LH59_24465 75471db8eda0981a749b626c3995b257 167 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 49 73 3.6E-48 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 LH59_24465 75471db8eda0981a749b626c3995b257 167 Pfam PF01467 Cytidylyltransferase-like 5 133 3.6E-19 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 LH59_24465 75471db8eda0981a749b626c3995b257 167 Gene3D G3DSA:3.40.50.620 1 165 1.6E-56 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LH59_27480 359711acd9e4e2d1e04e3b45fa3d01bc 350 Gene3D G3DSA:3.90.25.10 201 331 2.0E-119 T 14-10-2018 LH59_27480 359711acd9e4e2d1e04e3b45fa3d01bc 350 Gene3D G3DSA:3.40.50.720 3 323 2.0E-119 T 14-10-2018 LH59_27480 359711acd9e4e2d1e04e3b45fa3d01bc 350 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 3 337 9.9E-136 T 14-10-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 LH59_27480 359711acd9e4e2d1e04e3b45fa3d01bc 350 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 324 1.5E-83 T 14-10-2018 IPR016040 NAD(P)-binding domain LH59_27480 359711acd9e4e2d1e04e3b45fa3d01bc 350 SUPERFAMILY SSF51735 1 335 3.38E-83 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_18975 bce1cb32f55c58441d0bf52b685365d8 254 Gene3D G3DSA:3.55.50.30 57 162 9.7E-22 T 14-10-2018 LH59_18975 bce1cb32f55c58441d0bf52b685365d8 254 SMART SM00965 86 137 2.4E-8 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 LH59_14500 82e9c8981f4ba091cf1496715adfe7b1 223 SMART SM00421 155 212 1.0E-22 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_14500 82e9c8981f4ba091cf1496715adfe7b1 223 Gene3D G3DSA:3.40.50.12740 3 218 4.3E-69 T 14-10-2018 LH59_14500 82e9c8981f4ba091cf1496715adfe7b1 223 SMART SM00448 3 116 1.5E-31 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_14500 82e9c8981f4ba091cf1496715adfe7b1 223 SUPERFAMILY SSF46894 150 218 1.12E-21 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LH59_14500 82e9c8981f4ba091cf1496715adfe7b1 223 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 212 1.5E-20 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_14500 82e9c8981f4ba091cf1496715adfe7b1 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 7.6E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_14500 82e9c8981f4ba091cf1496715adfe7b1 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 7.6E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_14500 82e9c8981f4ba091cf1496715adfe7b1 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 7.6E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_14500 82e9c8981f4ba091cf1496715adfe7b1 223 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_14500 82e9c8981f4ba091cf1496715adfe7b1 223 SUPERFAMILY SSF52172 1 132 1.04E-34 T 14-10-2018 IPR011006 CheY-like superfamily LH59_14500 82e9c8981f4ba091cf1496715adfe7b1 223 Pfam PF00072 Response regulator receiver domain 5 117 2.1E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_12025 8ba8717e07b0c8071d0212010fc65c80 478 Gene3D G3DSA:1.20.1600.10 51 465 2.0E-112 T 14-10-2018 LH59_12025 8ba8717e07b0c8071d0212010fc65c80 478 SUPERFAMILY SSF56954 2 469 6.93E-98 T 14-10-2018 LH59_12025 8ba8717e07b0c8071d0212010fc65c80 478 Gene3D G3DSA:2.20.200.10 99 353 2.0E-112 T 14-10-2018 LH59_12025 8ba8717e07b0c8071d0212010fc65c80 478 Pfam PF02321 Outer membrane efflux protein 287 462 1.3E-32 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 LH59_12025 8ba8717e07b0c8071d0212010fc65c80 478 Pfam PF02321 Outer membrane efflux protein 61 254 4.2E-14 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 LH59_12025 8ba8717e07b0c8071d0212010fc65c80 478 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 2 464 2.8E-116 T 14-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 LH59_13340 82c9c181f917a529c20cc7934c95437c 147 Gene3D G3DSA:3.30.700.10 39 145 1.6E-35 T 14-10-2018 LH59_13340 82c9c181f917a529c20cc7934c95437c 147 Pfam PF08334 Type II secretion system (T2SS), protein G 37 145 3.7E-39 T 14-10-2018 IPR013545 Type II secretion system protein G LH59_13340 82c9c181f917a529c20cc7934c95437c 147 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 12 34 1.6E-9 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site LH59_13340 82c9c181f917a529c20cc7934c95437c 147 Pfam PF07963 Prokaryotic N-terminal methylation motif 9 34 4.6E-11 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site LH59_13340 82c9c181f917a529c20cc7934c95437c 147 TIGRFAM TIGR01710 typeII_sec_gspG: type II secretion system protein G 13 146 8.1E-54 T 14-10-2018 IPR010054 General secretion pathway protein G GO:0008565|GO:0015627|GO:0015628 LH59_13340 82c9c181f917a529c20cc7934c95437c 147 PRINTS PR00813 Bacterial general secretion pathway protein G signature 14 39 9.2E-18 T 14-10-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 LH59_13340 82c9c181f917a529c20cc7934c95437c 147 PRINTS PR00813 Bacterial general secretion pathway protein G signature 50 68 9.2E-18 T 14-10-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 LH59_13340 82c9c181f917a529c20cc7934c95437c 147 SUPERFAMILY SSF54523 41 145 6.8E-35 T 14-10-2018 LH59_13340 82c9c181f917a529c20cc7934c95437c 147 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 13 33 - T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site LH59_15905 3094b2f83ea0710ea89a53828f7c43e2 320 SUPERFAMILY SSF46689 265 315 4.48E-7 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_15905 3094b2f83ea0710ea89a53828f7c43e2 320 SUPERFAMILY SSF52317 6 194 3.71E-47 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_15905 3094b2f83ea0710ea89a53828f7c43e2 320 Gene3D G3DSA:3.40.50.880 3 206 6.5E-58 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_15905 3094b2f83ea0710ea89a53828f7c43e2 320 SUPERFAMILY SSF46689 212 262 4.94E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_15905 3094b2f83ea0710ea89a53828f7c43e2 320 Pfam PF01965 DJ-1/PfpI family 47 172 6.4E-17 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 LH59_15905 3094b2f83ea0710ea89a53828f7c43e2 320 SMART SM00342 228 312 4.4E-22 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_15905 3094b2f83ea0710ea89a53828f7c43e2 320 Gene3D G3DSA:1.10.10.60 212 317 1.8E-24 T 14-10-2018 LH59_15905 3094b2f83ea0710ea89a53828f7c43e2 320 Pfam PF12833 Helix-turn-helix domain 234 313 6.3E-20 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_13505 babe1f4ae8d3262929243abd3267d842 152 Pfam PF07681 DoxX 16 95 2.1E-7 T 14-10-2018 IPR032808 DoxX family LH59_10235 70e8d07b27620712f270d960094e327c 263 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 261 4.5E-58 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 LH59_10235 70e8d07b27620712f270d960094e327c 263 SUPERFAMILY SSF52096 4 261 1.61E-80 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily LH59_10235 70e8d07b27620712f270d960094e327c 263 Gene3D G3DSA:1.10.12.10 205 262 3.7E-20 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal LH59_10235 70e8d07b27620712f270d960094e327c 263 Gene3D G3DSA:3.90.226.10 5 204 1.2E-66 T 14-10-2018 LH59_19865 a3cc733842b281223eb8b2cdb3565e2f 502 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 264 469 2.7E-25 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_19865 a3cc733842b281223eb8b2cdb3565e2f 502 SUPERFAMILY SSF161098 245 468 4.06E-16 T 14-10-2018 IPR035906 MetI-like superfamily LH59_19865 a3cc733842b281223eb8b2cdb3565e2f 502 Gene3D G3DSA:1.10.3720.10 234 464 3.3E-17 T 14-10-2018 IPR035906 MetI-like superfamily LH59_23520 95b2aaba565c466cdb9b70c91508cb90 229 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 189 1.2E-21 T 14-10-2018 LH59_23520 95b2aaba565c466cdb9b70c91508cb90 229 Gene3D G3DSA:3.40.50.1000 8 211 6.7E-58 T 14-10-2018 IPR023214 HAD superfamily LH59_23520 95b2aaba565c466cdb9b70c91508cb90 229 SUPERFAMILY SSF56784 5 223 4.56E-53 T 14-10-2018 IPR036412 HAD-like superfamily LH59_23520 95b2aaba565c466cdb9b70c91508cb90 229 Gene3D G3DSA:1.10.150.240 21 87 6.7E-58 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 LH59_23520 95b2aaba565c466cdb9b70c91508cb90 229 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 93 190 7.2E-14 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 LH59_13940 3fd800e2a6ca838443249a3dc84be093 276 Gene3D G3DSA:1.10.3720.10 71 264 4.2E-24 T 14-10-2018 IPR035906 MetI-like superfamily LH59_13940 3fd800e2a6ca838443249a3dc84be093 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 262 4.0E-23 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_13940 3fd800e2a6ca838443249a3dc84be093 276 SUPERFAMILY SSF161098 70 256 4.84E-32 T 14-10-2018 IPR035906 MetI-like superfamily LH59_05705 06fb6716df383a7a7741a6e5259f495c 411 Pfam PF07690 Major Facilitator Superfamily 31 350 8.2E-28 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_05705 06fb6716df383a7a7741a6e5259f495c 411 Gene3D G3DSA:1.20.1250.20 20 397 4.0E-41 T 14-10-2018 LH59_05705 06fb6716df383a7a7741a6e5259f495c 411 SUPERFAMILY SSF103473 16 397 2.22E-53 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_04950 4be0bd59a605bd13a9d4e234e4bcba91 74 Pfam PF05433 Glycine zipper 2TM domain 34 72 1.8E-7 T 14-10-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 LH59_04830 f369ec744505d0e780cce9edc3b03247 382 SUPERFAMILY SSF53822 25 381 2.77E-72 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_04830 f369ec744505d0e780cce9edc3b03247 382 Gene3D G3DSA:3.40.50.2300 142 371 8.6E-109 T 14-10-2018 LH59_04830 f369ec744505d0e780cce9edc3b03247 382 Gene3D G3DSA:3.40.50.2300 27 364 8.6E-109 T 14-10-2018 LH59_04830 f369ec744505d0e780cce9edc3b03247 382 Pfam PF13458 Periplasmic binding protein 24 362 1.0E-50 T 14-10-2018 IPR028081 Leucine-binding protein domain LH59_23080 938f157424289964c83874e76024929d 609 Pfam PF01425 Amidase 73 445 1.7E-85 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_23080 938f157424289964c83874e76024929d 609 TIGRFAM TIGR02713 allophanate_hyd: allophanate hydrolase 45 602 1.8E-253 T 14-10-2018 IPR014085 Allophanate hydrolase KEGG: 00220+3.5.1.54|KEGG: 00791+3.5.1.54|MetaCyc: PWY-5169|MetaCyc: PWY-5703 LH59_23080 938f157424289964c83874e76024929d 609 Gene3D G3DSA:3.90.1300.10 44 449 3.6E-163 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_23080 938f157424289964c83874e76024929d 609 Gene3D G3DSA:1.20.58.1700 302 375 3.6E-163 T 14-10-2018 LH59_23080 938f157424289964c83874e76024929d 609 SUPERFAMILY SSF75304 38 457 1.57E-109 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_23080 938f157424289964c83874e76024929d 609 Gene3D G3DSA:3.10.490.10 478 608 5.8E-53 T 14-10-2018 LH59_08665 39a7bf149628e6f14144c5600135f449 454 SUPERFAMILY SSF58113 53 177 9.29E-6 T 14-10-2018 LH59_08665 39a7bf149628e6f14144c5600135f449 454 Pfam PF02646 RmuC family 139 426 3.9E-75 T 14-10-2018 IPR003798 DNA recombination RmuC LH59_08665 39a7bf149628e6f14144c5600135f449 454 Gene3D G3DSA:1.20.120.20 55 194 5.4E-7 T 14-10-2018 LH59_22785 6e7056545312d496c002ce608d9e7473 157 Gene3D G3DSA:3.40.390.30 4 157 4.6E-38 T 14-10-2018 IPR023091 Metalloprotease catalytic domain superfamily, predicted GO:0004222 LH59_22785 6e7056545312d496c002ce608d9e7473 157 Pfam PF02130 Uncharacterized protein family UPF0054 28 147 9.0E-28 T 14-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 LH59_22785 6e7056545312d496c002ce608d9e7473 157 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 4 152 19.593 T 14-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 LH59_22785 6e7056545312d496c002ce608d9e7473 157 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 46 148 8.3E-27 T 14-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 LH59_22785 6e7056545312d496c002ce608d9e7473 157 SUPERFAMILY SSF55486 33 154 2.2E-36 T 14-10-2018 LH59_00495 2373462bb8743e4b1c617450055669d6 550 SUPERFAMILY SSF56801 14 544 3.27E-144 T 14-10-2018 LH59_00495 2373462bb8743e4b1c617450055669d6 550 ProSitePatterns PS00455 Putative AMP-binding domain signature. 191 202 - T 14-10-2018 IPR020845 AMP-binding, conserved site LH59_00495 2373462bb8743e4b1c617450055669d6 550 Gene3D G3DSA:3.30.300.310 443 545 9.3E-33 T 14-10-2018 LH59_00495 2373462bb8743e4b1c617450055669d6 550 Pfam PF00501 AMP-binding enzyme 29 447 4.3E-95 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 LH59_00495 2373462bb8743e4b1c617450055669d6 550 Gene3D G3DSA:3.40.50.12780 9 442 2.9E-110 T 14-10-2018 LH59_00495 2373462bb8743e4b1c617450055669d6 550 Pfam PF13193 AMP-binding enzyme C-terminal domain 456 530 1.8E-21 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain LH59_24010 bef2675f331ce97b05cc6076099eb3c8 132 Pfam PF05239 PRC-barrel domain 21 98 6.6E-16 T 14-10-2018 IPR027275 PRC-barrel domain LH59_24010 bef2675f331ce97b05cc6076099eb3c8 132 Gene3D G3DSA:2.30.30.240 16 103 3.5E-25 T 14-10-2018 LH59_24010 bef2675f331ce97b05cc6076099eb3c8 132 SUPERFAMILY SSF50346 17 132 8.63E-27 T 14-10-2018 IPR011033 PRC-barrel-like superfamily LH59_18530 187b61f69cb45e03638d7e184502738c 126 Gene3D G3DSA:3.10.290.10 1 101 4.3E-35 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 LH59_18530 187b61f69cb45e03638d7e184502738c 126 PIRSF PIRSF016821 1 126 1.6E-44 T 14-10-2018 IPR025708 Heat shock protein 15 GO:0003677|GO:0003727|GO:0034605|GO:0043023 LH59_18530 187b61f69cb45e03638d7e184502738c 126 SMART SM00363 4 69 3.5E-9 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_18530 187b61f69cb45e03638d7e184502738c 126 SUPERFAMILY SSF55174 2 99 1.06E-27 T 14-10-2018 LH59_18530 187b61f69cb45e03638d7e184502738c 126 Pfam PF01479 S4 domain 5 50 1.5E-12 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_07355 d1c32f52cd272375c7e38ccdc43fda13 304 SUPERFAMILY SSF52768 2 303 6.71E-103 T 14-10-2018 IPR023696 Ureohydrolase domain superfamily LH59_07355 d1c32f52cd272375c7e38ccdc43fda13 304 Gene3D G3DSA:3.40.800.20 1 304 6.2E-122 T 14-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 LH59_07355 d1c32f52cd272375c7e38ccdc43fda13 304 Pfam PF00850 Histone deacetylase domain 17 301 8.1E-84 T 14-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 LH59_07355 d1c32f52cd272375c7e38ccdc43fda13 304 PRINTS PR01270 Histone deacetylase superfamily signature 231 241 6.8E-18 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 LH59_07355 d1c32f52cd272375c7e38ccdc43fda13 304 PRINTS PR01270 Histone deacetylase superfamily signature 153 168 6.8E-18 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 LH59_07355 d1c32f52cd272375c7e38ccdc43fda13 304 PRINTS PR01270 Histone deacetylase superfamily signature 119 142 6.8E-18 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 LH59_02855 c7398bc66657a2ceb69bee54975f49c1 478 Pfam PF13416 Bacterial extracellular solute-binding protein 70 369 1.4E-21 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein LH59_02855 c7398bc66657a2ceb69bee54975f49c1 478 SUPERFAMILY SSF53850 54 468 3.32E-32 T 14-10-2018 LH59_02855 c7398bc66657a2ceb69bee54975f49c1 478 Gene3D G3DSA:3.40.190.10 48 467 5.9E-37 T 14-10-2018 LH59_27825 d8a695a39ee926e9bae35acffac5a81f 319 SUPERFAMILY SSF51215 78 170 9.55E-5 T 14-10-2018 IPR037923 Transcription regulator HTH-like LH59_27825 d8a695a39ee926e9bae35acffac5a81f 319 Pfam PF14525 AraC-binding-like domain 20 196 3.5E-22 T 14-10-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like LH59_27825 d8a695a39ee926e9bae35acffac5a81f 319 SUPERFAMILY SSF46689 267 318 1.84E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_27825 d8a695a39ee926e9bae35acffac5a81f 319 Pfam PF12833 Helix-turn-helix domain 238 318 1.8E-16 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_27825 d8a695a39ee926e9bae35acffac5a81f 319 SMART SM00342 231 316 4.5E-20 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_27825 d8a695a39ee926e9bae35acffac5a81f 319 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 300 316 8.3E-6 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 LH59_27825 d8a695a39ee926e9bae35acffac5a81f 319 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 285 300 8.3E-6 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 LH59_27825 d8a695a39ee926e9bae35acffac5a81f 319 Gene3D G3DSA:1.10.10.60 210 319 1.4E-25 T 14-10-2018 LH59_27095 e83dce9db4877ec8f11d80b8b7038b5d 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 3.5E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_27095 e83dce9db4877ec8f11d80b8b7038b5d 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 3.5E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_27095 e83dce9db4877ec8f11d80b8b7038b5d 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 3.5E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_27095 e83dce9db4877ec8f11d80b8b7038b5d 307 SUPERFAMILY SSF46785 4 112 6.81E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_27095 e83dce9db4877ec8f11d80b8b7038b5d 307 SUPERFAMILY SSF53850 89 297 6.15E-47 T 14-10-2018 LH59_27095 e83dce9db4877ec8f11d80b8b7038b5d 307 Gene3D G3DSA:3.40.190.10 91 290 1.5E-66 T 14-10-2018 LH59_27095 e83dce9db4877ec8f11d80b8b7038b5d 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 8.5E-20 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_27095 e83dce9db4877ec8f11d80b8b7038b5d 307 Gene3D G3DSA:3.40.190.10 163 264 1.5E-66 T 14-10-2018 LH59_27095 e83dce9db4877ec8f11d80b8b7038b5d 307 Gene3D G3DSA:1.10.10.10 3 89 1.1E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_27095 e83dce9db4877ec8f11d80b8b7038b5d 307 Pfam PF03466 LysR substrate binding domain 88 293 3.1E-44 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_10335 16323df3b15f4d75c125208f33d60a68 299 SUPERFAMILY SSF53850 87 284 1.76E-34 T 14-10-2018 LH59_10335 16323df3b15f4d75c125208f33d60a68 299 Gene3D G3DSA:3.40.190.10 91 276 2.0E-23 T 14-10-2018 LH59_10335 16323df3b15f4d75c125208f33d60a68 299 Gene3D G3DSA:1.10.10.10 1 90 1.1E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_10335 16323df3b15f4d75c125208f33d60a68 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.4E-14 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_10335 16323df3b15f4d75c125208f33d60a68 299 Pfam PF03466 LysR substrate binding domain 89 286 1.5E-37 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_10335 16323df3b15f4d75c125208f33d60a68 299 SUPERFAMILY SSF46785 1 83 3.48E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_10335 16323df3b15f4d75c125208f33d60a68 299 Gene3D G3DSA:3.40.190.10 163 265 2.0E-23 T 14-10-2018 LH59_22355 48d138574c2b66c1d038ff75e2897aa9 299 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 17 270 3.7E-43 T 14-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region LH59_22355 48d138574c2b66c1d038ff75e2897aa9 299 Gene3D G3DSA:2.120.10.30 1 275 3.4E-42 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like LH59_22355 48d138574c2b66c1d038ff75e2897aa9 299 SUPERFAMILY SSF63829 6 293 1.96E-50 T 14-10-2018 LH59_18720 b1dba968ff1d72490105713988e66414 170 Gene3D G3DSA:1.20.120.450 1 170 5.2E-61 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes LH59_18720 b1dba968ff1d72490105713988e66414 170 Pfam PF09351 Domain of unknown function (DUF1993) 5 165 2.1E-63 T 14-10-2018 IPR018531 Protein of unknown function DUF1993 LH59_18720 b1dba968ff1d72490105713988e66414 170 SUPERFAMILY SSF109854 4 168 1.65E-61 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes LH59_25435 c242d27b0b242d1b1898306b610fef7d 95 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 78 95 - T 14-10-2018 IPR010917 TonB-dependent receptor, conserved site LH59_25435 c242d27b0b242d1b1898306b610fef7d 95 Gene3D G3DSA:2.40.170.20 1 95 1.4E-23 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_25435 c242d27b0b242d1b1898306b610fef7d 95 SUPERFAMILY SSF56935 13 95 3.85E-13 T 14-10-2018 LH59_25435 c242d27b0b242d1b1898306b610fef7d 95 Pfam PF00593 TonB dependent receptor 15 94 2.9E-10 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_25000 971c69e2082b355ed237c4bed78491d4 248 TIGRFAM TIGR01829 AcAcCoA_reduct: acetoacetyl-CoA reductase 5 247 1.5E-102 T 14-10-2018 IPR011283 Acetoacetyl-CoA reductase GO:0005737|GO:0018454|GO:0042619|GO:0055114 KEGG: 00630+1.1.1.36|KEGG: 00650+1.1.1.36|MetaCyc: PWY-5676|MetaCyc: PWY-5741|MetaCyc: PWY-7216|MetaCyc: PWY-7948 LH59_25000 971c69e2082b355ed237c4bed78491d4 248 SUPERFAMILY SSF51735 4 247 8.98E-80 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_25000 971c69e2082b355ed237c4bed78491d4 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LH59_25000 971c69e2082b355ed237c4bed78491d4 248 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 246 3.2E-60 T 14-10-2018 LH59_25000 971c69e2082b355ed237c4bed78491d4 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 185 1.6E-5 T 14-10-2018 LH59_25000 971c69e2082b355ed237c4bed78491d4 248 Gene3D G3DSA:3.40.50.720 2 248 1.1E-81 T 14-10-2018 LH59_25000 971c69e2082b355ed237c4bed78491d4 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 1.7E-16 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25000 971c69e2082b355ed237c4bed78491d4 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 1.7E-16 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25000 971c69e2082b355ed237c4bed78491d4 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 1.7E-16 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25000 971c69e2082b355ed237c4bed78491d4 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 1.9E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25000 971c69e2082b355ed237c4bed78491d4 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.9E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25000 971c69e2082b355ed237c4bed78491d4 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.9E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25000 971c69e2082b355ed237c4bed78491d4 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.9E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25000 971c69e2082b355ed237c4bed78491d4 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.9E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25000 971c69e2082b355ed237c4bed78491d4 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.9E-46 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_26085 95f21169dff3a4bdf4bdf0059e497460 329 Gene3D G3DSA:3.40.190.10 129 252 1.6E-119 T 14-10-2018 LH59_26085 95f21169dff3a4bdf4bdf0059e497460 329 SUPERFAMILY SSF53850 114 290 3.44E-14 T 14-10-2018 LH59_26085 95f21169dff3a4bdf4bdf0059e497460 329 Gene3D G3DSA:3.40.190.150 32 319 1.6E-119 T 14-10-2018 LH59_26085 95f21169dff3a4bdf4bdf0059e497460 329 PIRSF PIRSF017082 1 329 8.6E-86 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_26085 95f21169dff3a4bdf4bdf0059e497460 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 51 324 3.0E-97 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_00240 9ab3f4fbfb5ac7ca947e5a986fcf3f44 509 SUPERFAMILY SSF52540 258 495 9.77E-37 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_00240 9ab3f4fbfb5ac7ca947e5a986fcf3f44 509 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_00240 9ab3f4fbfb5ac7ca947e5a986fcf3f44 509 Pfam PF00005 ABC transporter 24 172 1.8E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_00240 9ab3f4fbfb5ac7ca947e5a986fcf3f44 509 Pfam PF00005 ABC transporter 279 436 6.8E-13 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_00240 9ab3f4fbfb5ac7ca947e5a986fcf3f44 509 Gene3D G3DSA:3.40.50.300 3 246 1.8E-57 T 14-10-2018 LH59_00240 9ab3f4fbfb5ac7ca947e5a986fcf3f44 509 SMART SM00382 32 219 2.8E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_00240 9ab3f4fbfb5ac7ca947e5a986fcf3f44 509 Gene3D G3DSA:3.40.50.300 247 500 5.1E-36 T 14-10-2018 LH59_00240 9ab3f4fbfb5ac7ca947e5a986fcf3f44 509 ProSitePatterns PS00211 ABC transporters family signature. 409 423 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_00240 9ab3f4fbfb5ac7ca947e5a986fcf3f44 509 SUPERFAMILY SSF52540 7 227 1.43E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_04365 84feed71ecc20928c398b75a15117a83 346 SUPERFAMILY SSF56112 10 325 7.0E-48 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily LH59_04365 84feed71ecc20928c398b75a15117a83 346 Gene3D G3DSA:3.90.1200.10 99 340 5.1E-71 T 14-10-2018 LH59_04365 84feed71ecc20928c398b75a15117a83 346 Pfam PF01636 Phosphotransferase enzyme family 30 258 2.6E-35 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase LH59_04365 84feed71ecc20928c398b75a15117a83 346 Gene3D G3DSA:3.30.200.20 5 98 1.9E-23 T 14-10-2018 LH59_00330 c5deda0f444586a79db883d8c4f80c49 352 Pfam PF09084 NMT1/THI5 like 51 269 3.1E-22 T 14-10-2018 IPR015168 SsuA/THI5-like LH59_00330 c5deda0f444586a79db883d8c4f80c49 352 Gene3D G3DSA:3.40.190.10 50 321 8.8E-49 T 14-10-2018 LH59_00330 c5deda0f444586a79db883d8c4f80c49 352 SUPERFAMILY SSF53850 40 278 2.26E-32 T 14-10-2018 LH59_00330 c5deda0f444586a79db883d8c4f80c49 352 Gene3D G3DSA:3.40.190.10 121 232 8.8E-49 T 14-10-2018 LH59_21700 a551edcfc10d7f8ba9017425a18c207c 282 SUPERFAMILY SSF161098 11 273 2.71E-49 T 14-10-2018 IPR035906 MetI-like superfamily LH59_21700 a551edcfc10d7f8ba9017425a18c207c 282 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 270 1.3E-8 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_21700 a551edcfc10d7f8ba9017425a18c207c 282 Gene3D G3DSA:1.10.3720.10 8 277 2.1E-58 T 14-10-2018 IPR035906 MetI-like superfamily LH59_10215 53e5e02407010b349efa4083eab53a06 311 SUPERFAMILY SSF103481 45 148 2.62E-10 T 14-10-2018 LH59_10215 53e5e02407010b349efa4083eab53a06 311 SUPERFAMILY SSF103481 196 299 1.44E-12 T 14-10-2018 LH59_10215 53e5e02407010b349efa4083eab53a06 311 Pfam PF00892 EamA-like transporter family 161 296 1.7E-18 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_10215 53e5e02407010b349efa4083eab53a06 311 Pfam PF00892 EamA-like transporter family 15 144 2.0E-14 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_18015 a16d2b09a80a7a8a91da02bfd1caf54b 368 Gene3D G3DSA:1.10.1530.10 23 360 7.4E-111 T 14-10-2018 LH59_18015 a16d2b09a80a7a8a91da02bfd1caf54b 368 SUPERFAMILY SSF89733 13 364 6.67E-97 T 14-10-2018 IPR036111 Malate/L-sulfolactate/L-lactate dehydrogenase-like superfamily GO:0016491|GO:0055114 LH59_18015 a16d2b09a80a7a8a91da02bfd1caf54b 368 Gene3D G3DSA:3.30.1370.60 75 328 7.4E-111 T 14-10-2018 LH59_18015 a16d2b09a80a7a8a91da02bfd1caf54b 368 Pfam PF02615 Malate/L-lactate dehydrogenase 15 354 1.0E-107 T 14-10-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0016491|GO:0055114 LH59_05355 d88d6bd209c2c2b4f2b79e726bf7b2b6 293 Gene3D G3DSA:3.40.50.300 13 216 4.8E-28 T 14-10-2018 LH59_05355 d88d6bd209c2c2b4f2b79e726bf7b2b6 293 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 41 187 2.2E-14 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 LH59_05355 d88d6bd209c2c2b4f2b79e726bf7b2b6 293 SUPERFAMILY SSF52540 19 248 2.18E-37 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_05355 d88d6bd209c2c2b4f2b79e726bf7b2b6 293 SMART SM00382 37 195 2.6E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_00665 c3d05d57f4df61b18dbcd79de38ef715 431 Pfam PF13416 Bacterial extracellular solute-binding protein 50 366 3.9E-50 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein LH59_00665 c3d05d57f4df61b18dbcd79de38ef715 431 Gene3D G3DSA:3.40.190.10 149 421 6.6E-111 T 14-10-2018 LH59_00665 c3d05d57f4df61b18dbcd79de38ef715 431 SUPERFAMILY SSF53850 30 424 8.4E-79 T 14-10-2018 LH59_00665 c3d05d57f4df61b18dbcd79de38ef715 431 Gene3D G3DSA:3.40.190.10 38 385 6.6E-111 T 14-10-2018 LH59_03390 ead628c27e5f62866a579bdc35afb2f3 369 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 5 369 40.373 T 14-10-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 MetaCyc: PWY-7883 LH59_03390 ead628c27e5f62866a579bdc35afb2f3 369 Pfam PF03702 Anhydro-N-acetylmuramic acid kinase 6 369 3.6E-138 T 14-10-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 MetaCyc: PWY-7883 LH59_03390 ead628c27e5f62866a579bdc35afb2f3 369 Gene3D G3DSA:3.30.420.40 12 364 1.1E-116 T 14-10-2018 LH59_03390 ead628c27e5f62866a579bdc35afb2f3 369 Gene3D G3DSA:3.30.420.40 145 329 1.1E-116 T 14-10-2018 LH59_03390 ead628c27e5f62866a579bdc35afb2f3 369 SUPERFAMILY SSF53067 7 340 5.33E-26 T 14-10-2018 LH59_01065 06d77f53ce17bba450a5926d7faccd8a 291 SUPERFAMILY SSF50891 92 247 9.48E-29 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily LH59_01065 06d77f53ce17bba450a5926d7faccd8a 291 Gene3D G3DSA:3.30.1360.40 1 83 5.8E-15 T 14-10-2018 LH59_01065 06d77f53ce17bba450a5926d7faccd8a 291 SUPERFAMILY SSF160467 4 95 2.35E-15 T 14-10-2018 LH59_01065 06d77f53ce17bba450a5926d7faccd8a 291 SMART SM00796 3 231 2.6E-67 T 14-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D LH59_01065 06d77f53ce17bba450a5926d7faccd8a 291 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 4 223 4.0E-51 T 14-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D LH59_01065 06d77f53ce17bba450a5926d7faccd8a 291 Gene3D G3DSA:2.40.100.10 84 288 2.0E-56 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily LH59_10770 7be7602336d594188d988bbf740c89d4 543 SUPERFAMILY SSF56801 15 536 2.75E-143 T 14-10-2018 LH59_10770 7be7602336d594188d988bbf740c89d4 543 ProSitePatterns PS00455 Putative AMP-binding domain signature. 186 197 - T 14-10-2018 IPR020845 AMP-binding, conserved site LH59_10770 7be7602336d594188d988bbf740c89d4 543 Gene3D G3DSA:3.40.50.12780 18 433 6.4E-106 T 14-10-2018 LH59_10770 7be7602336d594188d988bbf740c89d4 543 Pfam PF00501 AMP-binding enzyme 31 438 5.1E-92 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 LH59_10770 7be7602336d594188d988bbf740c89d4 543 Gene3D G3DSA:3.30.300.310 436 538 2.5E-30 T 14-10-2018 LH59_10770 7be7602336d594188d988bbf740c89d4 543 Pfam PF13193 AMP-binding enzyme C-terminal domain 449 524 6.1E-19 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain LH59_20605 c762abf0a9c7f240892d84d34dfd05d3 301 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 143 173 - T 14-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 LH59_20605 c762abf0a9c7f240892d84d34dfd05d3 301 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 48 65 - T 14-10-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LH59_20605 c762abf0a9c7f240892d84d34dfd05d3 301 SMART SM01130 11 299 4.5E-141 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_20605 c762abf0a9c7f240892d84d34dfd05d3 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 81 99 1.1E-35 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_20605 c762abf0a9c7f240892d84d34dfd05d3 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 45 66 1.1E-35 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_20605 c762abf0a9c7f240892d84d34dfd05d3 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 113 129 1.1E-35 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_20605 c762abf0a9c7f240892d84d34dfd05d3 301 PRINTS PR00146 Dihydrodipicolinate synthase signature 138 155 1.1E-35 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_20605 c762abf0a9c7f240892d84d34dfd05d3 301 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 11 297 66.696 T 14-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LH59_20605 c762abf0a9c7f240892d84d34dfd05d3 301 Pfam PF00701 Dihydrodipicolinate synthetase family 11 297 6.4E-103 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_20605 c762abf0a9c7f240892d84d34dfd05d3 301 Gene3D G3DSA:3.20.20.70 12 301 5.0E-109 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_20605 c762abf0a9c7f240892d84d34dfd05d3 301 SUPERFAMILY SSF51569 11 299 8.58E-104 T 14-10-2018 LH59_20605 c762abf0a9c7f240892d84d34dfd05d3 301 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 15 297 6.2E-107 T 14-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 LH59_20605 c762abf0a9c7f240892d84d34dfd05d3 301 PIRSF PIRSF001365 7 301 8.6E-97 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_04705 d291cd013ea362d2b3599fa7bb3f6b4a 174 Pfam PF01613 Flavin reductase like domain 18 160 2.4E-34 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 LH59_04705 d291cd013ea362d2b3599fa7bb3f6b4a 174 Gene3D G3DSA:2.30.110.10 6 170 6.1E-48 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 LH59_04705 d291cd013ea362d2b3599fa7bb3f6b4a 174 SUPERFAMILY SSF50475 9 160 5.4E-46 T 14-10-2018 LH59_04705 d291cd013ea362d2b3599fa7bb3f6b4a 174 SMART SM00903 17 162 2.2E-57 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 LH59_23455 c0d43b70c7bfdd07773134add54e7ae4 178 SUPERFAMILY SSF55729 19 162 3.44E-28 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_23455 c0d43b70c7bfdd07773134add54e7ae4 178 Gene3D G3DSA:3.40.630.30 7 178 8.5E-50 T 14-10-2018 LH59_23455 c0d43b70c7bfdd07773134add54e7ae4 178 Pfam PF13673 Acetyltransferase (GNAT) domain 61 154 1.4E-15 T 14-10-2018 IPR000182 GNAT domain LH59_16915 2b38a647f6c67881f4b49b2aa51329da 216 PIRSF PIRSF006324 6 213 7.8E-58 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 LH59_16915 2b38a647f6c67881f4b49b2aa51329da 216 Pfam PF01810 LysE type translocator 19 209 6.3E-33 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 LH59_25185 17990b062a2f71da1bace5fe27668639 261 Gene3D G3DSA:1.10.10.10 157 255 1.7E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_25185 17990b062a2f71da1bace5fe27668639 261 SMART SM00421 194 251 1.6E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_25185 17990b062a2f71da1bace5fe27668639 261 SUPERFAMILY SSF46894 185 251 2.35E-13 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LH59_25185 17990b062a2f71da1bace5fe27668639 261 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 227 239 1.3E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_25185 17990b062a2f71da1bace5fe27668639 261 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 211 227 1.3E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_25185 17990b062a2f71da1bace5fe27668639 261 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 197 211 1.3E-8 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_25185 17990b062a2f71da1bace5fe27668639 261 Pfam PF00196 Bacterial regulatory proteins, luxR family 196 247 1.0E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_25185 17990b062a2f71da1bace5fe27668639 261 ProSitePatterns PS00622 LuxR-type HTH domain signature. 211 238 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_08150 b8cc82c5a79ddb7e0dc51a156e4d6a52 128 Gene3D G3DSA:4.10.430.10 79 128 1.9E-17 T 14-10-2018 IPR037150 Histone-like protein H-NS, C-terminal domain superfamily GO:0003677 LH59_08150 b8cc82c5a79ddb7e0dc51a156e4d6a52 128 SMART SM00528 82 126 7.4E-19 T 14-10-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 LH59_08150 b8cc82c5a79ddb7e0dc51a156e4d6a52 128 SUPERFAMILY SSF81273 85 127 7.06E-11 T 14-10-2018 LH59_08150 b8cc82c5a79ddb7e0dc51a156e4d6a52 128 Pfam PF00816 H-NS histone family 12 119 2.4E-23 T 14-10-2018 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 LH59_02580 9f66c7de1185ebcf2b832c284ea0b268 243 PIRSF PIRSF039085 1 240 8.0E-109 T 14-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 LH59_02580 9f66c7de1185ebcf2b832c284ea0b268 243 SUPERFAMILY SSF52540 2 235 2.08E-79 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_02580 9f66c7de1185ebcf2b832c284ea0b268 243 Gene3D G3DSA:3.40.50.300 1 239 1.5E-77 T 14-10-2018 LH59_02580 9f66c7de1185ebcf2b832c284ea0b268 243 Pfam PF00005 ABC transporter 17 165 4.6E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_02580 9f66c7de1185ebcf2b832c284ea0b268 243 SMART SM00382 26 209 5.0E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_02580 9f66c7de1185ebcf2b832c284ea0b268 243 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_25905 467ac33c44a9b9b85972ac2b8b2d2e9f 552 Gene3D G3DSA:1.10.10.10 153 249 6.0E-8 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_25905 467ac33c44a9b9b85972ac2b8b2d2e9f 552 SUPERFAMILY SSF141868 269 517 4.58E-56 T 14-10-2018 IPR035919 EAL domain superfamily LH59_25905 467ac33c44a9b9b85972ac2b8b2d2e9f 552 SUPERFAMILY SSF46894 159 243 1.53E-8 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LH59_25905 467ac33c44a9b9b85972ac2b8b2d2e9f 552 Gene3D G3DSA:3.20.20.450 269 532 1.6E-65 T 14-10-2018 IPR035919 EAL domain superfamily LH59_25905 467ac33c44a9b9b85972ac2b8b2d2e9f 552 SMART SM00052 263 511 1.5E-45 T 14-10-2018 IPR001633 EAL domain LH59_25905 467ac33c44a9b9b85972ac2b8b2d2e9f 552 Pfam PF00563 EAL domain 272 506 1.8E-50 T 14-10-2018 IPR001633 EAL domain LH59_27430 7a3fee3f51305a01f2ded3cecb54ed8c 286 Gene3D G3DSA:3.40.50.150 41 195 1.4E-28 T 14-10-2018 LH59_27430 7a3fee3f51305a01f2ded3cecb54ed8c 286 SUPERFAMILY SSF53335 2 181 3.35E-26 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_27430 7a3fee3f51305a01f2ded3cecb54ed8c 286 Pfam PF08241 Methyltransferase domain 64 158 4.4E-16 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 LH59_19765 c891092feceeae4bbd0340d948ce180b 235 Pfam PF11180 Protein of unknown function (DUF2968) 43 222 3.2E-68 T 14-10-2018 IPR021350 Protein of unknown function DUF2968 LH59_24095 908bb1e74494910ee5a45772a7b16d47 168 SUPERFAMILY SSF88659 94 164 1.48E-10 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like LH59_24095 908bb1e74494910ee5a45772a7b16d47 168 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 14 166 7.1E-19 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 LH59_24095 908bb1e74494910ee5a45772a7b16d47 168 Gene3D G3DSA:1.10.1740.10 9 81 5.5E-9 T 14-10-2018 LH59_24095 908bb1e74494910ee5a45772a7b16d47 168 Gene3D G3DSA:1.10.10.10 91 168 1.1E-8 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_24095 908bb1e74494910ee5a45772a7b16d47 168 SUPERFAMILY SSF88946 12 99 1.14E-14 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 LH59_24095 908bb1e74494910ee5a45772a7b16d47 168 Pfam PF04542 Sigma-70 region 2 15 81 4.0E-13 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 LH59_24095 908bb1e74494910ee5a45772a7b16d47 168 Pfam PF08281 Sigma-70, region 4 111 164 1.7E-11 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LH59_27260 3a96509a501984cc18ec93caca0d2a09 279 SUPERFAMILY SSF52540 19 252 5.03E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_27260 3a96509a501984cc18ec93caca0d2a09 279 Gene3D G3DSA:3.40.50.300 18 261 1.0E-60 T 14-10-2018 LH59_27260 3a96509a501984cc18ec93caca0d2a09 279 Pfam PF00005 ABC transporter 37 186 1.2E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_27260 3a96509a501984cc18ec93caca0d2a09 279 SMART SM00382 45 243 1.4E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_09595 86fc3c715d4c86e64164a99672095c40 475 Gene3D G3DSA:3.80.30.20 20 381 8.1E-120 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe LH59_09595 86fc3c715d4c86e64164a99672095c40 475 Pfam PF06969 HemN C-terminal domain 381 448 4.4E-9 T 14-10-2018 IPR010723 HemN, C-terminal LH59_09595 86fc3c715d4c86e64164a99672095c40 475 Gene3D G3DSA:1.10.10.920 382 475 6.1E-27 T 14-10-2018 LH59_09595 86fc3c715d4c86e64164a99672095c40 475 SUPERFAMILY SSF102114 21 462 2.35E-132 T 14-10-2018 LH59_09595 86fc3c715d4c86e64164a99672095c40 475 TIGRFAM TIGR00538 hemN: oxygen-independent coproporphyrinogen III oxidase 24 475 1.5E-164 T 14-10-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00860+1.3.98.3|MetaCyc: PWY-5531 LH59_09595 86fc3c715d4c86e64164a99672095c40 475 PIRSF PIRSF000167 20 472 2.6E-162 T 14-10-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00860+1.3.98.3|MetaCyc: PWY-5531 LH59_09595 86fc3c715d4c86e64164a99672095c40 475 Pfam PF04055 Radical SAM superfamily 74 245 1.1E-17 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 LH59_09595 86fc3c715d4c86e64164a99672095c40 475 SMART SM00729 69 287 2.9E-47 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 LH59_10445 7356aaf778aabdc6e81de0b61f530848 406 SUPERFAMILY SSF48695 19 196 8.28E-53 T 14-10-2018 IPR036280 Multiheme cytochrome superfamily LH59_10445 7356aaf778aabdc6e81de0b61f530848 406 PIRSF PIRSF000014 8 401 1.5E-138 T 14-10-2018 IPR009154 Membrane-bound tetrahaem cytochrome TorC/YecK GO:0005506|GO:0009055|GO:0009276|GO:0016021|GO:0020037 LH59_10445 7356aaf778aabdc6e81de0b61f530848 406 TIGRFAM TIGR02162 torC: trimethylamine-N-oxide reductase c-type cytochrome TorC 18 399 7.1E-154 T 14-10-2018 IPR009154 Membrane-bound tetrahaem cytochrome TorC/YecK GO:0005506|GO:0009055|GO:0009276|GO:0016021|GO:0020037 LH59_10445 7356aaf778aabdc6e81de0b61f530848 406 Gene3D G3DSA:1.10.3820.10 23 200 4.1E-37 T 14-10-2018 IPR038266 NapC/NirT cytochrome c superfamily LH59_10445 7356aaf778aabdc6e81de0b61f530848 406 Pfam PF03264 NapC/NirT cytochrome c family, N-terminal region 23 194 7.8E-69 T 14-10-2018 IPR005126 NapC/NirT cytochrome c, N-terminal LH59_24750 be7257bfa6eb2e6b709ca5aaaf2fb13d 161 SUPERFAMILY SSF53597 5 160 3.02E-55 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 LH59_24750 be7257bfa6eb2e6b709ca5aaaf2fb13d 161 Pfam PF00186 Dihydrofolate reductase 5 160 3.8E-57 T 14-10-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0046654|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 LH59_24750 be7257bfa6eb2e6b709ca5aaaf2fb13d 161 Gene3D G3DSA:3.40.430.10 3 161 1.1E-59 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 LH59_24750 be7257bfa6eb2e6b709ca5aaaf2fb13d 161 PIRSF PIRSF000194 1 161 9.1E-60 T 14-10-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0046654|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614 LH59_24750 be7257bfa6eb2e6b709ca5aaaf2fb13d 161 PRINTS PR00070 Dihydrofolate reductase signature 16 26 1.9E-16 T 14-10-2018 LH59_24750 be7257bfa6eb2e6b709ca5aaaf2fb13d 161 PRINTS PR00070 Dihydrofolate reductase signature 30 38 1.9E-16 T 14-10-2018 LH59_24750 be7257bfa6eb2e6b709ca5aaaf2fb13d 161 PRINTS PR00070 Dihydrofolate reductase signature 43 54 1.9E-16 T 14-10-2018 LH59_24750 be7257bfa6eb2e6b709ca5aaaf2fb13d 161 PRINTS PR00070 Dihydrofolate reductase signature 94 108 1.9E-16 T 14-10-2018 LH59_24750 be7257bfa6eb2e6b709ca5aaaf2fb13d 161 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 16 38 - T 14-10-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 LH59_22765 3c285cc1a896e35b46c3cfc4a175d11d 237 SMART SM00863 190 233 4.0E-15 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 LH59_22765 3c285cc1a896e35b46c3cfc4a175d11d 237 SUPERFAMILY SSF55186 97 234 8.5E-32 T 14-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 LH59_22765 3c285cc1a896e35b46c3cfc4a175d11d 237 SUPERFAMILY SSF50447 3 93 7.06E-12 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily LH59_22765 3c285cc1a896e35b46c3cfc4a175d11d 237 Pfam PF01411 tRNA synthetases class II (A) 17 96 1.5E-6 T 14-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 LH59_22765 3c285cc1a896e35b46c3cfc4a175d11d 237 Gene3D G3DSA:2.40.30.130 1 92 1.7E-15 T 14-10-2018 LH59_22765 3c285cc1a896e35b46c3cfc4a175d11d 237 Gene3D G3DSA:3.30.980.10 94 237 1.1E-32 T 14-10-2018 LH59_22765 3c285cc1a896e35b46c3cfc4a175d11d 237 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 190 233 1.5E-12 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 LH59_08775 c4cbb4bc0a6233505f988ce3ba2977e4 591 Gene3D G3DSA:3.40.50.300 337 589 2.5E-91 T 14-10-2018 LH59_08775 c4cbb4bc0a6233505f988ce3ba2977e4 591 Pfam PF00005 ABC transporter 368 517 4.9E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_08775 c4cbb4bc0a6233505f988ce3ba2977e4 591 SMART SM00382 376 549 6.4E-18 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_08775 c4cbb4bc0a6233505f988ce3ba2977e4 591 Pfam PF00664 ABC transporter transmembrane region 35 304 4.1E-43 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 LH59_08775 c4cbb4bc0a6233505f988ce3ba2977e4 591 SUPERFAMILY SSF52540 342 588 1.55E-89 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_08775 c4cbb4bc0a6233505f988ce3ba2977e4 591 SUPERFAMILY SSF90123 22 334 4.45E-70 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 LH59_08775 c4cbb4bc0a6233505f988ce3ba2977e4 591 Gene3D G3DSA:1.20.1560.10 4 336 5.4E-72 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 LH59_08775 c4cbb4bc0a6233505f988ce3ba2977e4 591 TIGRFAM TIGR02203 MsbA_lipidA: lipid A export permease/ATP-binding protein MsbA 20 590 1.1E-261 T 14-10-2018 IPR011917 ABC transporter, lipid A export, MsbA GO:0005524|GO:0016021|GO:0034040 LH59_08775 c4cbb4bc0a6233505f988ce3ba2977e4 591 ProSitePatterns PS00211 ABC transporters family signature. 489 503 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_14235 c71fd8eb27aba407bb03807411d85308 393 Gene3D G3DSA:2.120.10.30 34 226 8.4E-9 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like LH59_14235 c71fd8eb27aba407bb03807411d85308 393 SUPERFAMILY SSF69304 56 364 6.8E-12 T 14-10-2018 LH59_13995 6910d0311fd3b38906ae7b0b3d593e2a 348 Gene3D G3DSA:2.120.10.30 43 348 5.2E-105 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like LH59_13995 6910d0311fd3b38906ae7b0b3d593e2a 348 SUPERFAMILY SSF63829 33 346 2.4E-72 T 14-10-2018 LH59_13995 6910d0311fd3b38906ae7b0b3d593e2a 348 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 72 335 1.7E-62 T 14-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region LH59_24345 27d43e87ec337b8168686c0c029e591e 306 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 293 5.2E-36 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_14705 c4095eec6256d39e8cd85b1baf051d19 228 Pfam PF01625 Peptide methionine sulfoxide reductase 47 199 1.5E-56 T 14-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 LH59_14705 c4095eec6256d39e8cd85b1baf051d19 228 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 46 196 1.5E-50 T 14-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 LH59_14705 c4095eec6256d39e8cd85b1baf051d19 228 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 45 205 35.597 T 14-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 LH59_14705 c4095eec6256d39e8cd85b1baf051d19 228 Gene3D G3DSA:3.30.1060.10 25 209 2.8E-61 T 14-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 LH59_14705 c4095eec6256d39e8cd85b1baf051d19 228 SUPERFAMILY SSF55068 38 208 1.83E-66 T 14-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 LH59_14625 e269461997db5d66b509fe94ec5fe3b4 60 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 22 55 1.3E-8 T 14-10-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.1.98.6|KEGG: 00240+1.1.98.6|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 LH59_07550 10d2601da1cea80fbead81ccb39bb435 225 TIGRFAM TIGR00608 radc: DNA repair protein RadC 12 223 2.8E-65 T 14-10-2018 IPR001405 Uncharacterised protein family UPF0758 LH59_07550 10d2601da1cea80fbead81ccb39bb435 225 Pfam PF04002 RadC-like JAB domain 105 222 1.5E-40 T 14-10-2018 IPR025657 RadC-like JAB domain LH59_07550 10d2601da1cea80fbead81ccb39bb435 225 SUPERFAMILY SSF47781 16 90 2.57E-11 T 14-10-2018 IPR010994 RuvA domain 2-like LH59_07550 10d2601da1cea80fbead81ccb39bb435 225 Gene3D G3DSA:1.10.150.20 29 88 2.8E-5 T 14-10-2018 LH59_07550 10d2601da1cea80fbead81ccb39bb435 225 Gene3D G3DSA:3.40.140.10 101 224 1.1E-38 T 14-10-2018 LH59_07550 10d2601da1cea80fbead81ccb39bb435 225 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 174 179 - T 14-10-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site LH59_07550 10d2601da1cea80fbead81ccb39bb435 225 SUPERFAMILY SSF102712 151 201 7.32E-5 T 14-10-2018 LH59_00145 5010bc67911cb3bf44924368ed8fdf88 312 SUPERFAMILY SSF51735 96 278 7.18E-47 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_00145 5010bc67911cb3bf44924368ed8fdf88 312 Gene3D G3DSA:3.40.50.720 16 312 6.8E-106 T 14-10-2018 LH59_00145 5010bc67911cb3bf44924368ed8fdf88 312 SUPERFAMILY SSF52283 17 124 9.23E-8 T 14-10-2018 LH59_00145 5010bc67911cb3bf44924368ed8fdf88 312 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 103 277 5.5E-45 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 LH59_00145 5010bc67911cb3bf44924368ed8fdf88 312 Gene3D G3DSA:3.40.50.720 94 278 6.8E-106 T 14-10-2018 LH59_00530 216f4bfe930ae92cc709ff5217e9e0c0 382 SUPERFAMILY SSF53901 15 349 7.5E-30 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_00530 216f4bfe930ae92cc709ff5217e9e0c0 382 Gene3D G3DSA:3.40.47.10 5 378 4.9E-96 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_00530 216f4bfe930ae92cc709ff5217e9e0c0 382 Pfam PF00108 Thiolase, N-terminal domain 10 221 1.9E-8 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 LH59_00530 216f4bfe930ae92cc709ff5217e9e0c0 382 PIRSF PIRSF000429 1 377 1.4E-28 T 14-10-2018 IPR002155 Thiolase GO:0016747 LH59_26620 7a53d72f8d434f63a1a22b0e861cb539 200 Gene3D G3DSA:3.40.50.1000 23 190 6.1E-49 T 14-10-2018 IPR023214 HAD superfamily LH59_26620 7a53d72f8d434f63a1a22b0e861cb539 200 SUPERFAMILY SSF56784 27 184 8.27E-39 T 14-10-2018 IPR036412 HAD-like superfamily LH59_26620 7a53d72f8d434f63a1a22b0e861cb539 200 PIRSF PIRSF006118 17 190 1.3E-59 T 14-10-2018 IPR010023 KdsC family GO:0016788 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 LH59_26620 7a53d72f8d434f63a1a22b0e861cb539 200 Pfam PF08282 haloacid dehalogenase-like hydrolase 95 162 1.8E-7 T 14-10-2018 LH59_26620 7a53d72f8d434f63a1a22b0e861cb539 200 TIGRFAM TIGR01670 KdsC-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family 30 181 6.7E-42 T 14-10-2018 IPR010023 KdsC family GO:0016788 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 LH59_02310 1c0af824ea7dc3e2a0c0a870da0a9beb 314 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 31 243 5.4E-13 T 14-10-2018 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0016788 LH59_02310 1c0af824ea7dc3e2a0c0a870da0a9beb 314 SUPERFAMILY SSF53187 3 310 6.73E-55 T 14-10-2018 LH59_02310 1c0af824ea7dc3e2a0c0a870da0a9beb 314 Gene3D G3DSA:3.40.630.10 15 312 8.4E-49 T 14-10-2018 LH59_24025 6bcc24ad48d11b99fea5225c8848b097 159 SUPERFAMILY SSF54593 4 157 3.38E-50 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_24025 6bcc24ad48d11b99fea5225c8848b097 159 Gene3D G3DSA:3.10.180.70 1 159 7.7E-60 T 14-10-2018 LH59_24025 6bcc24ad48d11b99fea5225c8848b097 159 PIRSF PIRSF021700 1 159 5.5E-65 T 14-10-2018 IPR009725 Predicted 3-demethylubiquinone-9 3-methyltransferase LH59_24025 6bcc24ad48d11b99fea5225c8848b097 159 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 4 119 6.8E-44 T 14-10-2018 IPR028973 PhnB-like LH59_15730 9553c0a2cd5a045f2f8181aa9fa39700 217 Gene3D G3DSA:3.40.50.850 8 213 1.0E-59 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 LH59_15730 9553c0a2cd5a045f2f8181aa9fa39700 217 Pfam PF00857 Isochorismatase family 30 203 1.1E-42 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 LH59_15730 9553c0a2cd5a045f2f8181aa9fa39700 217 SUPERFAMILY SSF52499 16 209 9.55E-53 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 LH59_07480 d3a2a0b5461feb304a933f810c950ceb 329 Pfam PF05138 Phenylacetic acid catabolic protein 36 311 3.0E-105 T 14-10-2018 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 LH59_07480 d3a2a0b5461feb304a933f810c950ceb 329 TIGRFAM TIGR02156 PA_CoA_Oxy1: phenylacetate-CoA oxygenase, PaaG subunit 26 315 1.7E-166 T 14-10-2018 IPR011881 1,2-phenylacetyl-CoA epoxidase, subunit A GO:0010124|GO:0097266 KEGG: 00360+1.14.13.149 LH59_07480 d3a2a0b5461feb304a933f810c950ceb 329 Gene3D G3DSA:1.20.1260.10 19 329 3.0E-134 T 14-10-2018 IPR012347 Ferritin-like LH59_07480 d3a2a0b5461feb304a933f810c950ceb 329 SUPERFAMILY SSF47240 46 289 2.11E-83 T 14-10-2018 IPR009078 Ferritin-like superfamily LH59_06745 f999c06aa79dea4179d2164e7d9bd3ce 326 Gene3D G3DSA:3.60.20.30 193 326 5.9E-52 T 14-10-2018 LH59_06745 f999c06aa79dea4179d2164e7d9bd3ce 326 SUPERFAMILY SSF56235 3 324 2.24E-100 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal LH59_06745 f999c06aa79dea4179d2164e7d9bd3ce 326 Pfam PF01112 Asparaginase 4 325 5.1E-122 T 14-10-2018 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 LH59_08030 87f21821f123bfbedd1dad1c502a7eab 414 Pfam PF04375 HemX, putative uroporphyrinogen-III C-methyltransferase 56 403 1.2E-43 T 14-10-2018 IPR007470 Putative uroporphyrinogen-III C-methyltransferase HemX LH59_07135 0742273dfcc66be2ccb0cd7713b3b097 871 Gene3D G3DSA:3.30.1490.20 219 309 4.2E-18 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 LH59_07135 0742273dfcc66be2ccb0cd7713b3b097 871 SUPERFAMILY SSF56059 219 494 3.36E-33 T 14-10-2018 LH59_07135 0742273dfcc66be2ccb0cd7713b3b097 871 TIGRFAM TIGR02068 cya_phycin_syn: cyanophycin synthetase 7 868 0.0 T 14-10-2018 IPR011810 Cyanophycin synthetase GO:0005524|GO:0009059|GO:0016874 MetaCyc: PWY-7052 LH59_07135 0742273dfcc66be2ccb0cd7713b3b097 871 Gene3D G3DSA:3.90.190.20 728 856 2.4E-10 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 LH59_07135 0742273dfcc66be2ccb0cd7713b3b097 871 SUPERFAMILY SSF53244 726 867 1.23E-15 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 LH59_07135 0742273dfcc66be2ccb0cd7713b3b097 871 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 219 304 1.4E-6 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 LH59_07135 0742273dfcc66be2ccb0cd7713b3b097 871 SUPERFAMILY SSF53623 480 715 5.1E-31 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 LH59_07135 0742273dfcc66be2ccb0cd7713b3b097 871 Gene3D G3DSA:3.40.1190.10 478 716 1.6E-31 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 LH59_07135 0742273dfcc66be2ccb0cd7713b3b097 871 Pfam PF08245 Mur ligase middle domain 486 698 1.1E-13 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 LH59_07135 0742273dfcc66be2ccb0cd7713b3b097 871 Gene3D G3DSA:3.30.470.20 377 473 1.6E-6 T 14-10-2018 LH59_12400 38bbbca6ed82b4ba89577d42919897cc 130 Gene3D G3DSA:1.10.1660.10 1 125 1.8E-33 T 14-10-2018 LH59_12400 38bbbca6ed82b4ba89577d42919897cc 130 TIGRFAM TIGR02044 CueR: Cu(I)-responsive transcriptional regulator 1 126 2.9E-54 T 14-10-2018 IPR011789 Cu(I)-responsive transcriptional regulator GO:0003677|GO:0003700|GO:0005507|GO:0045893 LH59_12400 38bbbca6ed82b4ba89577d42919897cc 130 SUPERFAMILY SSF46955 1 126 1.25E-37 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily LH59_12400 38bbbca6ed82b4ba89577d42919897cc 130 Pfam PF09278 MerR, DNA binding 44 108 4.9E-17 T 14-10-2018 IPR015358 Transcription regulator MerR, DNA binding LH59_12400 38bbbca6ed82b4ba89577d42919897cc 130 SMART SM00422 1 70 4.2E-31 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LH59_12400 38bbbca6ed82b4ba89577d42919897cc 130 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 3.5E-11 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LH59_12400 38bbbca6ed82b4ba89577d42919897cc 130 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 3.5E-11 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LH59_12400 38bbbca6ed82b4ba89577d42919897cc 130 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 3.5E-11 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LH59_12400 38bbbca6ed82b4ba89577d42919897cc 130 Pfam PF00376 MerR family regulatory protein 2 39 4.2E-16 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LH59_12400 38bbbca6ed82b4ba89577d42919897cc 130 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LH59_18765 c3068c4c95c7a52dda2122eda3973d92 298 Pfam PF12146 Serine aminopeptidase, S33 96 253 2.8E-11 T 14-10-2018 IPR022742 Serine aminopeptidase, S33 LH59_18765 c3068c4c95c7a52dda2122eda3973d92 298 SUPERFAMILY SSF53474 79 292 7.3E-34 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_18765 c3068c4c95c7a52dda2122eda3973d92 298 Gene3D G3DSA:3.40.50.1820 74 294 1.4E-32 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_06395 9446055be4677f3c4481e5e4553fdfeb 169 Pfam PF03358 NADPH-dependent FMN reductase 44 124 5.6E-8 T 14-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 LH59_06395 9446055be4677f3c4481e5e4553fdfeb 169 SUPERFAMILY SSF52218 1 165 2.57E-29 T 14-10-2018 IPR029039 Flavoprotein-like superfamily LH59_06395 9446055be4677f3c4481e5e4553fdfeb 169 Gene3D G3DSA:3.40.50.360 1 167 1.9E-21 T 14-10-2018 IPR029039 Flavoprotein-like superfamily LH59_19995 0cc06fc6505a265ad47bf5538455d1a6 300 SUPERFAMILY SSF53448 31 232 6.13E-51 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases LH59_19995 0cc06fc6505a265ad47bf5538455d1a6 300 Pfam PF00535 Glycosyl transferase family 2 34 189 6.7E-27 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 LH59_19995 0cc06fc6505a265ad47bf5538455d1a6 300 Gene3D G3DSA:3.90.550.10 6 256 4.5E-50 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases LH59_05420 8f822e8bd9d2b636f1e4b721ab558e9e 202 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 11 198 35.616 T 14-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 LH59_05420 8f822e8bd9d2b636f1e4b721ab558e9e 202 Pfam PF02669 K+-transporting ATPase, c chain 15 197 7.3E-74 T 14-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 LH59_05420 8f822e8bd9d2b636f1e4b721ab558e9e 202 TIGRFAM TIGR00681 kdpC: K+-transporting ATPase, C subunit 14 198 1.8E-72 T 14-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 LH59_05420 8f822e8bd9d2b636f1e4b721ab558e9e 202 PIRSF PIRSF001296 10 202 2.3E-76 T 14-10-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 LH59_19785 6b310f9ec5e01cc1fc25d2e1df9170ac 292 SMART SM00028 169 202 62.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 LH59_19785 6b310f9ec5e01cc1fc25d2e1df9170ac 292 SMART SM00028 135 168 0.0023 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 LH59_19785 6b310f9ec5e01cc1fc25d2e1df9170ac 292 SUPERFAMILY SSF48452 79 229 2.6E-16 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_19785 6b310f9ec5e01cc1fc25d2e1df9170ac 292 Pfam PF13432 Tetratricopeptide repeat 141 202 2.8E-8 T 14-10-2018 LH59_19785 6b310f9ec5e01cc1fc25d2e1df9170ac 292 Gene3D G3DSA:1.25.40.10 22 259 4.3E-21 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_19785 6b310f9ec5e01cc1fc25d2e1df9170ac 292 PIRSF PIRSF029658 10 284 4.3E-77 T 14-10-2018 IPR016931 Uncharacterised conserved protein UCP029658, TPR LH59_08600 ab5af1899494032476ce8d620d57d765 425 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 6 413 1.8E-116 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit LH59_08600 ab5af1899494032476ce8d620d57d765 425 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 416 3.2E-131 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 LH59_08600 ab5af1899494032476ce8d620d57d765 425 PIRSF PIRSF006066 1 425 4.2E-164 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 LH59_13070 70883dce8218b39ebaf6667b8898a0f8 293 Gene3D G3DSA:3.20.20.60 1 292 9.5E-92 T 14-10-2018 LH59_13070 70883dce8218b39ebaf6667b8898a0f8 293 PIRSF PIRSF015582 1 291 2.1E-78 T 14-10-2018 IPR011206 Citrate lyase beta subunit-like LH59_13070 70883dce8218b39ebaf6667b8898a0f8 293 SUPERFAMILY SSF51621 6 233 2.08E-68 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 LH59_13070 70883dce8218b39ebaf6667b8898a0f8 293 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 9 223 1.5E-49 T 14-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 LH59_18055 b705a3e5edf3ab0e71f8ea3e008a8de8 454 Pfam PF13481 AAA domain 83 221 1.3E-17 T 14-10-2018 LH59_18055 b705a3e5edf3ab0e71f8ea3e008a8de8 454 SUPERFAMILY SSF54211 254 453 8.72E-40 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold LH59_18055 b705a3e5edf3ab0e71f8ea3e008a8de8 454 PRINTS PR01874 DNA repair protein radA signature 173 197 1.9E-94 T 14-10-2018 LH59_18055 b705a3e5edf3ab0e71f8ea3e008a8de8 454 PRINTS PR01874 DNA repair protein radA signature 123 140 1.9E-94 T 14-10-2018 LH59_18055 b705a3e5edf3ab0e71f8ea3e008a8de8 454 PRINTS PR01874 DNA repair protein radA signature 247 273 1.9E-94 T 14-10-2018 LH59_18055 b705a3e5edf3ab0e71f8ea3e008a8de8 454 PRINTS PR01874 DNA repair protein radA signature 212 240 1.9E-94 T 14-10-2018 LH59_18055 b705a3e5edf3ab0e71f8ea3e008a8de8 454 PRINTS PR01874 DNA repair protein radA signature 321 344 1.9E-94 T 14-10-2018 LH59_18055 b705a3e5edf3ab0e71f8ea3e008a8de8 454 PRINTS PR01874 DNA repair protein radA signature 10 34 1.9E-94 T 14-10-2018 LH59_18055 b705a3e5edf3ab0e71f8ea3e008a8de8 454 PRINTS PR01874 DNA repair protein radA signature 82 110 1.9E-94 T 14-10-2018 LH59_18055 b705a3e5edf3ab0e71f8ea3e008a8de8 454 Hamap MF_01498 DNA repair protein RadA [radA]. 21 454 43.645 T 14-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 LH59_18055 b705a3e5edf3ab0e71f8ea3e008a8de8 454 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 450 8.1E-194 T 14-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 LH59_18055 b705a3e5edf3ab0e71f8ea3e008a8de8 454 Gene3D G3DSA:3.40.50.300 65 282 3.7E-42 T 14-10-2018 LH59_18055 b705a3e5edf3ab0e71f8ea3e008a8de8 454 Gene3D G3DSA:3.30.230.10 311 454 3.2E-14 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup LH59_18055 b705a3e5edf3ab0e71f8ea3e008a8de8 454 SUPERFAMILY SSF52540 68 288 1.24E-51 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_18055 b705a3e5edf3ab0e71f8ea3e008a8de8 454 SMART SM00382 90 243 2.8E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_14220 3e7c11fc65754db7c5a942b728008966 204 SMART SM00448 8 118 1.0E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_14220 3e7c11fc65754db7c5a942b728008966 204 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 187 4.6E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_14220 3e7c11fc65754db7c5a942b728008966 204 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 145 159 4.6E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_14220 3e7c11fc65754db7c5a942b728008966 204 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 175 4.6E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_14220 3e7c11fc65754db7c5a942b728008966 204 SUPERFAMILY SSF52172 8 161 4.98E-33 T 14-10-2018 IPR011006 CheY-like superfamily LH59_14220 3e7c11fc65754db7c5a942b728008966 204 SUPERFAMILY SSF46894 143 199 1.79E-16 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LH59_14220 3e7c11fc65754db7c5a942b728008966 204 SMART SM00421 142 199 1.0E-20 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_14220 3e7c11fc65754db7c5a942b728008966 204 Pfam PF00196 Bacterial regulatory proteins, luxR family 144 197 3.4E-20 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_14220 3e7c11fc65754db7c5a942b728008966 204 Gene3D G3DSA:1.10.10.10 135 201 8.0E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_14220 3e7c11fc65754db7c5a942b728008966 204 ProSitePatterns PS00622 LuxR-type HTH domain signature. 159 186 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_14220 3e7c11fc65754db7c5a942b728008966 204 Pfam PF00072 Response regulator receiver domain 10 118 1.8E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_14220 3e7c11fc65754db7c5a942b728008966 204 Gene3D G3DSA:3.40.50.2300 3 132 2.5E-38 T 14-10-2018 LH59_08165 98b14fd8e1f865410b50cf31f97609f8 469 SUPERFAMILY SSF56176 13 226 3.36E-71 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 LH59_08165 98b14fd8e1f865410b50cf31f97609f8 469 Gene3D G3DSA:3.30.70.2740 345 426 1.7E-11 T 14-10-2018 LH59_08165 98b14fd8e1f865410b50cf31f97609f8 469 Gene3D G3DSA:3.30.465.40 23 243 3.7E-75 T 14-10-2018 LH59_08165 98b14fd8e1f865410b50cf31f97609f8 469 Pfam PF02913 FAD linked oxidases, C-terminal domain 226 466 6.4E-69 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 LH59_08165 98b14fd8e1f865410b50cf31f97609f8 469 Pfam PF01565 FAD binding domain 52 188 2.5E-40 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 LH59_08165 98b14fd8e1f865410b50cf31f97609f8 469 Gene3D G3DSA:1.10.45.10 427 467 1.3E-15 T 14-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 LH59_08165 98b14fd8e1f865410b50cf31f97609f8 469 SUPERFAMILY SSF55103 229 469 8.83E-74 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 LH59_21060 a25e783ee57419a455412d86d25dcc85 347 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 41 333 5.1E-82 T 14-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 LH59_21060 a25e783ee57419a455412d86d25dcc85 347 SUPERFAMILY SSF53659 9 337 5.28E-88 T 14-10-2018 LH59_21060 a25e783ee57419a455412d86d25dcc85 347 Gene3D G3DSA:3.40.718.10 2 339 1.6E-101 T 14-10-2018 LH59_14655 d85b67519c3fe8a6aed4aa3e1f17d326 385 Gene3D G3DSA:3.20.20.70 13 381 4.9E-43 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_14655 d85b67519c3fe8a6aed4aa3e1f17d326 385 SUPERFAMILY SSF51412 15 357 1.83E-30 T 14-10-2018 LH59_14655 d85b67519c3fe8a6aed4aa3e1f17d326 385 Pfam PF03060 Nitronate monooxygenase 16 333 2.6E-28 T 14-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 LH59_01465 762037776aca8682803fe87b872cf3cd 405 Gene3D G3DSA:3.20.20.140 61 359 1.1E-160 T 14-10-2018 LH59_01465 762037776aca8682803fe87b872cf3cd 405 SUPERFAMILY SSF51556 60 359 1.02E-86 T 14-10-2018 IPR032466 Metal-dependent hydrolase LH59_01465 762037776aca8682803fe87b872cf3cd 405 Hamap MF_00372 Imidazolonepropionase [hutI]. 2 399 42.795 T 14-10-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 LH59_01465 762037776aca8682803fe87b872cf3cd 405 Gene3D G3DSA:2.30.40.10 8 395 1.1E-160 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 LH59_01465 762037776aca8682803fe87b872cf3cd 405 SUPERFAMILY SSF51338 1 397 2.68E-29 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 LH59_01465 762037776aca8682803fe87b872cf3cd 405 Pfam PF01979 Amidohydrolase family 57 385 5.3E-22 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 LH59_01465 762037776aca8682803fe87b872cf3cd 405 TIGRFAM TIGR01224 hutI: imidazolonepropionase 22 396 1.7E-147 T 14-10-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 LH59_01580 03646e6838e348e6ac693166408a28ba 145 Pfam PF00582 Universal stress protein family 1 145 2.2E-32 T 14-10-2018 IPR006016 UspA LH59_01580 03646e6838e348e6ac693166408a28ba 145 PRINTS PR01438 Universal stress protein signature 2 20 1.4E-16 T 14-10-2018 IPR006015 Universal stress protein A LH59_01580 03646e6838e348e6ac693166408a28ba 145 PRINTS PR01438 Universal stress protein signature 105 117 1.4E-16 T 14-10-2018 IPR006015 Universal stress protein A LH59_01580 03646e6838e348e6ac693166408a28ba 145 PRINTS PR01438 Universal stress protein signature 123 145 1.4E-16 T 14-10-2018 IPR006015 Universal stress protein A LH59_01580 03646e6838e348e6ac693166408a28ba 145 PIRSF PIRSF006276 1 145 7.7E-21 T 14-10-2018 IPR006015 Universal stress protein A LH59_01580 03646e6838e348e6ac693166408a28ba 145 SUPERFAMILY SSF52402 1 145 3.1E-34 T 14-10-2018 LH59_01580 03646e6838e348e6ac693166408a28ba 145 Gene3D G3DSA:3.40.50.620 1 145 2.7E-36 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LH59_02210 ae4b12565ba7ad7fac1fce5e440fb983 251 SUPERFAMILY SSF51735 1 204 1.0E-31 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_02210 ae4b12565ba7ad7fac1fce5e440fb983 251 Gene3D G3DSA:3.40.50.720 2 246 5.4E-33 T 14-10-2018 LH59_02210 ae4b12565ba7ad7fac1fce5e440fb983 251 Pfam PF13460 NAD(P)H-binding 7 173 2.8E-9 T 14-10-2018 IPR016040 NAD(P)-binding domain LH59_22130 69957f9c5cb47c24b0d6cbf6552699b1 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 61 76 3.9E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_22130 69957f9c5cb47c24b0d6cbf6552699b1 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 110 130 3.9E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_22130 69957f9c5cb47c24b0d6cbf6552699b1 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 80 96 3.9E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_22130 69957f9c5cb47c24b0d6cbf6552699b1 156 SMART SM00347 20 120 3.7E-14 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_22130 69957f9c5cb47c24b0d6cbf6552699b1 156 SUPERFAMILY SSF46785 4 138 2.04E-29 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_22130 69957f9c5cb47c24b0d6cbf6552699b1 156 Pfam PF12802 MarR family 26 84 1.2E-13 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_22130 69957f9c5cb47c24b0d6cbf6552699b1 156 ProSitePatterns PS01117 MarR-type HTH domain signature. 59 93 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site LH59_22130 69957f9c5cb47c24b0d6cbf6552699b1 156 Gene3D G3DSA:1.10.10.10 1 137 3.5E-32 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_15155 3c79b758ca92ce55133b144e13d0add5 433 Pfam PF07690 Major Facilitator Superfamily 28 394 1.1E-25 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_15155 3c79b758ca92ce55133b144e13d0add5 433 SUPERFAMILY SSF103473 7 426 9.16E-30 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_16815 456609b49193197ed9c0812ac6161ba2 198 Pfam PF02525 Flavodoxin-like fold 1 171 4.6E-46 T 14-10-2018 IPR003680 Flavodoxin-like fold LH59_16815 456609b49193197ed9c0812ac6161ba2 198 Gene3D G3DSA:3.40.50.360 1 196 6.5E-50 T 14-10-2018 IPR029039 Flavoprotein-like superfamily LH59_16815 456609b49193197ed9c0812ac6161ba2 198 SUPERFAMILY SSF52218 1 195 5.9E-51 T 14-10-2018 IPR029039 Flavoprotein-like superfamily LH59_28095 98c1f547bd46d9f6951931f80c3135ce 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 5.5E-16 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_28095 98c1f547bd46d9f6951931f80c3135ce 293 Gene3D G3DSA:3.40.190.10 96 260 1.0E-51 T 14-10-2018 LH59_28095 98c1f547bd46d9f6951931f80c3135ce 293 Pfam PF03466 LysR substrate binding domain 89 281 1.7E-25 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_28095 98c1f547bd46d9f6951931f80c3135ce 293 SUPERFAMILY SSF53850 90 281 5.74E-28 T 14-10-2018 LH59_28095 98c1f547bd46d9f6951931f80c3135ce 293 SUPERFAMILY SSF46785 4 111 2.51E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_28095 98c1f547bd46d9f6951931f80c3135ce 293 Gene3D G3DSA:3.40.190.10 162 255 1.0E-51 T 14-10-2018 LH59_28095 98c1f547bd46d9f6951931f80c3135ce 293 Gene3D G3DSA:1.10.10.10 1 86 3.9E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_28095 98c1f547bd46d9f6951931f80c3135ce 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 2.3E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_28095 98c1f547bd46d9f6951931f80c3135ce 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 2.3E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_28095 98c1f547bd46d9f6951931f80c3135ce 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 2.3E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_23790 eb882c800da6e8109e7a8fddcaacf1e6 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 1.8E-5 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_23790 eb882c800da6e8109e7a8fddcaacf1e6 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 1.8E-5 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_23790 eb882c800da6e8109e7a8fddcaacf1e6 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 1.8E-5 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_23790 eb882c800da6e8109e7a8fddcaacf1e6 216 SUPERFAMILY SSF46894 146 215 8.84E-16 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LH59_23790 eb882c800da6e8109e7a8fddcaacf1e6 216 SMART SM00448 4 121 3.1E-12 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_23790 eb882c800da6e8109e7a8fddcaacf1e6 216 SMART SM00421 152 209 5.9E-7 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_23790 eb882c800da6e8109e7a8fddcaacf1e6 216 Gene3D G3DSA:3.40.50.12740 4 215 3.2E-40 T 14-10-2018 LH59_23790 eb882c800da6e8109e7a8fddcaacf1e6 216 SUPERFAMILY SSF52172 3 133 1.28E-20 T 14-10-2018 IPR011006 CheY-like superfamily LH59_23790 eb882c800da6e8109e7a8fddcaacf1e6 216 Pfam PF00072 Response regulator receiver domain 6 121 2.4E-19 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_23790 eb882c800da6e8109e7a8fddcaacf1e6 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 207 7.7E-14 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_27070 1b451885f9bc8faf82b2f7ee089251b3 78 Pfam PF06945 Protein of unknown function (DUF1289) 26 70 3.2E-18 T 14-10-2018 IPR010710 Protein of unknown function DUF1289 LH59_25930 cf38263661c5cb2dd77c4e3286c568ec 242 Gene3D G3DSA:3.40.50.720 3 239 3.6E-65 T 14-10-2018 LH59_25930 cf38263661c5cb2dd77c4e3286c568ec 242 SUPERFAMILY SSF51735 7 237 8.0E-65 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_25930 cf38263661c5cb2dd77c4e3286c568ec 242 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 129 157 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LH59_25930 cf38263661c5cb2dd77c4e3286c568ec 242 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 236 3.2E-48 T 14-10-2018 LH59_25930 cf38263661c5cb2dd77c4e3286c568ec 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 123 131 7.7E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25930 cf38263661c5cb2dd77c4e3286c568ec 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 70 81 7.7E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25930 cf38263661c5cb2dd77c4e3286c568ec 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 161 7.7E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25930 cf38263661c5cb2dd77c4e3286c568ec 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 180 3.2E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25930 cf38263661c5cb2dd77c4e3286c568ec 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 161 3.2E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25930 cf38263661c5cb2dd77c4e3286c568ec 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 3.2E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25930 cf38263661c5cb2dd77c4e3286c568ec 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 70 81 3.2E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25930 cf38263661c5cb2dd77c4e3286c568ec 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 219 3.2E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_25930 cf38263661c5cb2dd77c4e3286c568ec 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 117 133 3.2E-36 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_17290 ce8a61875c344aaacc198b3a9409f38d 382 SMART SM01119 259 366 3.1E-40 T 14-10-2018 IPR026956 D-serine dehydratase-like domain LH59_17290 ce8a61875c344aaacc198b3a9409f38d 382 Gene3D G3DSA:3.20.20.10 20 241 1.0E-122 T 14-10-2018 IPR029066 PLP-binding barrel LH59_17290 ce8a61875c344aaacc198b3a9409f38d 382 Gene3D G3DSA:2.40.37.20 11 368 1.0E-122 T 14-10-2018 LH59_17290 ce8a61875c344aaacc198b3a9409f38d 382 Pfam PF14031 Putative serine dehydratase domain 259 365 8.6E-20 T 14-10-2018 IPR026956 D-serine dehydratase-like domain LH59_17290 ce8a61875c344aaacc198b3a9409f38d 382 SUPERFAMILY SSF51419 19 242 2.91E-34 T 14-10-2018 IPR029066 PLP-binding barrel LH59_17290 ce8a61875c344aaacc198b3a9409f38d 382 Pfam PF01168 Alanine racemase, N-terminal domain 19 244 2.4E-33 T 14-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 LH59_09010 88a869261825847200c97f09c190fb2c 207 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 85 196 2.2E-8 T 14-10-2018 IPR039538 BetI-type transcriptional repressor, C-terminal LH59_09010 88a869261825847200c97f09c190fb2c 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 2.9E-17 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_09010 88a869261825847200c97f09c190fb2c 207 Gene3D G3DSA:1.10.357.10 2 198 2.5E-37 T 14-10-2018 LH59_09010 88a869261825847200c97f09c190fb2c 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 2.8E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_09010 88a869261825847200c97f09c190fb2c 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 2.8E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_09010 88a869261825847200c97f09c190fb2c 207 SUPERFAMILY SSF46689 6 77 9.75E-19 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_09010 88a869261825847200c97f09c190fb2c 207 SUPERFAMILY SSF48498 82 197 2.71E-7 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily LH59_24390 841e65b04f79caa37c0f4fb5331560bb 168 SUPERFAMILY SSF101307 16 162 4.19E-34 T 14-10-2018 IPR036681 PgpA-like superfamily GO:0006629|GO:0008962 LH59_24390 841e65b04f79caa37c0f4fb5331560bb 168 Pfam PF04608 Phosphatidylglycerophosphatase A 21 161 7.5E-46 T 14-10-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 LH59_24390 841e65b04f79caa37c0f4fb5331560bb 168 PIRSF PIRSF006162 11 167 1.3E-37 T 14-10-2018 IPR026037 Phosphatidylglycerophosphatase A KEGG: 00564+3.1.3.27|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 LH59_27990 a907db3907ceac3b10820350ee19a2a7 233 PIRSF PIRSF002155 1 227 3.2E-76 T 14-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27990 a907db3907ceac3b10820350ee19a2a7 233 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 14-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 LH59_27990 a907db3907ceac3b10820350ee19a2a7 233 SUPERFAMILY SSF56808 6 225 2.35E-81 T 14-10-2018 IPR023674 Ribosomal protein L1-like LH59_27990 a907db3907ceac3b10820350ee19a2a7 233 Gene3D G3DSA:3.40.50.790 68 159 5.2E-78 T 14-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich LH59_27990 a907db3907ceac3b10820350ee19a2a7 233 Gene3D G3DSA:3.30.190.20 25 221 5.2E-78 T 14-10-2018 LH59_27990 a907db3907ceac3b10820350ee19a2a7 233 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 43.443 T 14-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 LH59_27990 a907db3907ceac3b10820350ee19a2a7 233 Pfam PF00687 Ribosomal protein L1p/L10e family 31 219 6.6E-50 T 14-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein LH59_27990 a907db3907ceac3b10820350ee19a2a7 233 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 228 1.6E-102 T 14-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 LH59_22930 f0a495a1c5b5b88b2badd65b9fe368ee 278 SUPERFAMILY SSF53927 32 274 3.61E-80 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 LH59_22930 f0a495a1c5b5b88b2badd65b9fe368ee 278 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 34 275 5.9E-70 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 LH59_22930 f0a495a1c5b5b88b2badd65b9fe368ee 278 PIRSF PIRSF015626 8 277 3.5E-80 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 LH59_22930 f0a495a1c5b5b88b2badd65b9fe368ee 278 Pfam PF02634 FdhD/NarQ family 37 274 3.0E-77 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 LH59_22930 f0a495a1c5b5b88b2badd65b9fe368ee 278 Gene3D G3DSA:3.10.20.10 39 122 1.7E-11 T 14-10-2018 LH59_22930 f0a495a1c5b5b88b2badd65b9fe368ee 278 Hamap MF_00187 Sulfur carrier protein FdhD [fdhD]. 11 275 35.114 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 LH59_22930 f0a495a1c5b5b88b2badd65b9fe368ee 278 Gene3D G3DSA:3.40.140.10 130 278 2.6E-50 T 14-10-2018 LH59_05920 3594282260b6dc2e2906d0aca579c042 506 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 270 285 - T 14-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 LH59_05920 3594282260b6dc2e2906d0aca579c042 506 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 208 221 - T 14-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 LH59_05920 3594282260b6dc2e2906d0aca579c042 506 SUPERFAMILY SSF52540 183 418 1.18E-70 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_05920 3594282260b6dc2e2906d0aca579c042 506 Gene3D G3DSA:3.40.50.300 173 354 3.3E-64 T 14-10-2018 LH59_05920 3594282260b6dc2e2906d0aca579c042 506 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 397 406 - T 14-10-2018 IPR025944 Sigma-54 interaction domain, conserved site LH59_05920 3594282260b6dc2e2906d0aca579c042 506 Gene3D G3DSA:1.10.8.60 355 419 2.4E-18 T 14-10-2018 LH59_05920 3594282260b6dc2e2906d0aca579c042 506 Gene3D G3DSA:1.10.10.60 453 505 1.2E-8 T 14-10-2018 LH59_05920 3594282260b6dc2e2906d0aca579c042 506 SUPERFAMILY SSF46689 455 504 1.61E-6 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_05920 3594282260b6dc2e2906d0aca579c042 506 Gene3D G3DSA:3.30.450.40 8 165 2.9E-9 T 14-10-2018 IPR029016 GAF-like domain superfamily LH59_05920 3594282260b6dc2e2906d0aca579c042 506 SUPERFAMILY SSF55781 19 165 1.74E-10 T 14-10-2018 LH59_05920 3594282260b6dc2e2906d0aca579c042 506 Pfam PF00158 Sigma-54 interaction domain 184 350 1.4E-67 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 LH59_05920 3594282260b6dc2e2906d0aca579c042 506 SMART SM00382 204 347 7.2E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_27315 2307ec27ffb0cba4534f30e637bb437e 392 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 11 385 7.5E-138 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase LH59_27315 2307ec27ffb0cba4534f30e637bb437e 392 SUPERFAMILY SSF53383 3 389 1.34E-112 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_27315 2307ec27ffb0cba4534f30e637bb437e 392 PIRSF PIRSF000390 1 392 5.0E-112 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase LH59_27315 2307ec27ffb0cba4534f30e637bb437e 392 Gene3D G3DSA:3.90.1150.10 258 391 7.7E-34 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_27315 2307ec27ffb0cba4534f30e637bb437e 392 Gene3D G3DSA:3.40.640.10 1 255 3.5E-100 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_11585 7cd9df97aaa4ed2cb0f71dbe4e2820ac 410 Pfam PF02515 CoA-transferase family III 15 382 6.1E-110 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 LH59_11585 7cd9df97aaa4ed2cb0f71dbe4e2820ac 410 Gene3D G3DSA:3.30.1540.10 241 333 4.0E-119 T 14-10-2018 LH59_11585 7cd9df97aaa4ed2cb0f71dbe4e2820ac 410 SUPERFAMILY SSF89796 10 404 3.27E-124 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily LH59_11585 7cd9df97aaa4ed2cb0f71dbe4e2820ac 410 Gene3D G3DSA:3.40.50.10540 14 399 4.0E-119 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily LH59_11985 fd6cf679940556e1e4ae162d2a884dbf 352 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 3 328 8.1E-79 T 14-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 LH59_11985 fd6cf679940556e1e4ae162d2a884dbf 352 SUPERFAMILY SSF51395 1 349 3.67E-118 T 14-10-2018 LH59_11985 fd6cf679940556e1e4ae162d2a884dbf 352 Gene3D G3DSA:3.20.20.70 1 352 1.2E-135 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_08035 8c3e0b35cdf33063837f39ec7f5c7a50 537 TIGRFAM TIGR00540 TPR_hemY_coli: heme biosynthesis-associated TPR protein 3 390 2.7E-86 T 14-10-2018 IPR005254 Heme biosynthesis-associated TPR protein GO:0016020|GO:0042168 LH59_08035 8c3e0b35cdf33063837f39ec7f5c7a50 537 Pfam PF07219 HemY protein N-terminus 26 133 1.3E-27 T 14-10-2018 IPR010817 HemY, N-terminal LH59_08035 8c3e0b35cdf33063837f39ec7f5c7a50 537 Gene3D G3DSA:1.25.40.10 161 418 6.0E-12 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_08035 8c3e0b35cdf33063837f39ec7f5c7a50 537 SUPERFAMILY SSF48452 254 382 1.57E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_03285 7520cf5832a8ef3f9dc7e32d069966fd 397 SUPERFAMILY SSF103473 9 391 1.7E-60 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_03285 7520cf5832a8ef3f9dc7e32d069966fd 397 Gene3D G3DSA:1.20.1250.20 7 182 1.1E-30 T 14-10-2018 LH59_03285 7520cf5832a8ef3f9dc7e32d069966fd 397 Pfam PF07690 Major Facilitator Superfamily 14 334 2.4E-43 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_03285 7520cf5832a8ef3f9dc7e32d069966fd 397 Gene3D G3DSA:1.20.1250.20 207 395 5.1E-21 T 14-10-2018 LH59_02340 ec0a000e9452c5c041c31dd243c85fe0 299 Pfam PF03547 Membrane transport protein 145 291 1.7E-14 T 14-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 LH59_21665 2aae88995f2bee4871fa387592c33f1f 174 SUPERFAMILY SSF53098 7 171 2.84E-42 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily LH59_21665 2aae88995f2bee4871fa387592c33f1f 174 SMART SM00479 7 173 1.2E-31 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III LH59_21665 2aae88995f2bee4871fa387592c33f1f 174 Pfam PF00929 Exonuclease 9 163 1.5E-21 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III LH59_21665 2aae88995f2bee4871fa387592c33f1f 174 Gene3D G3DSA:3.30.420.10 4 171 2.6E-41 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 LH59_10735 1820ef2d08463e262cd2ff4449c0eaaf 160 Pfam PF13412 Winged helix-turn-helix DNA-binding 6 53 3.1E-20 T 14-10-2018 LH59_10735 1820ef2d08463e262cd2ff4449c0eaaf 160 ProSitePatterns PS00519 AsnC-type HTH domain signature. 24 50 - T 14-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site LH59_10735 1820ef2d08463e262cd2ff4449c0eaaf 160 Gene3D G3DSA:3.30.70.920 60 143 5.0E-26 T 14-10-2018 LH59_10735 1820ef2d08463e262cd2ff4449c0eaaf 160 Pfam PF01037 Lrp/AsnC ligand binding domain 72 146 1.0E-22 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LH59_10735 1820ef2d08463e262cd2ff4449c0eaaf 160 SUPERFAMILY SSF54909 66 155 1.47E-20 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel LH59_10735 1820ef2d08463e262cd2ff4449c0eaaf 160 Gene3D G3DSA:1.10.10.10 1 59 3.0E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_10735 1820ef2d08463e262cd2ff4449c0eaaf 160 SMART SM00344 6 115 4.3E-47 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 LH59_10735 1820ef2d08463e262cd2ff4449c0eaaf 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 22 4.8E-18 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_10735 1820ef2d08463e262cd2ff4449c0eaaf 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 52 4.8E-18 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_10735 1820ef2d08463e262cd2ff4449c0eaaf 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 33 4.8E-18 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_10735 1820ef2d08463e262cd2ff4449c0eaaf 160 SUPERFAMILY SSF46785 5 65 1.04E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_27300 c4b0869727491a55efa1e8fb388faa4c 189 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 99 134 1.4E-5 T 14-10-2018 IPR001451 Hexapeptide repeat LH59_27300 c4b0869727491a55efa1e8fb388faa4c 189 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 30 63 2.8E-8 T 14-10-2018 IPR001451 Hexapeptide repeat LH59_27300 c4b0869727491a55efa1e8fb388faa4c 189 SUPERFAMILY SSF51161 2 156 3.4E-42 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily LH59_27300 c4b0869727491a55efa1e8fb388faa4c 189 Gene3D G3DSA:2.20.70.110 151 189 2.1E-22 T 14-10-2018 LH59_27300 c4b0869727491a55efa1e8fb388faa4c 189 Gene3D G3DSA:2.160.10.10 1 149 1.3E-46 T 14-10-2018 LH59_12615 de4c7b3164c4cfb826c506a63153ac06 242 Gene3D G3DSA:3.40.50.300 2 241 2.1E-77 T 14-10-2018 LH59_12615 de4c7b3164c4cfb826c506a63153ac06 242 SMART SM00382 28 215 6.5E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_12615 de4c7b3164c4cfb826c506a63153ac06 242 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_12615 de4c7b3164c4cfb826c506a63153ac06 242 PIRSF PIRSF039085 1 242 9.1E-111 T 14-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 LH59_12615 de4c7b3164c4cfb826c506a63153ac06 242 SUPERFAMILY SSF52540 3 237 1.85E-80 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_12615 de4c7b3164c4cfb826c506a63153ac06 242 Pfam PF00005 ABC transporter 19 167 1.2E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_17660 c3f996248155dd1a9cf5535acc8c636d 101 Pfam PF01817 Chorismate mutase type II 15 89 3.3E-16 T 14-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 LH59_17660 c3f996248155dd1a9cf5535acc8c636d 101 SUPERFAMILY SSF48600 8 94 5.04E-21 T 14-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 LH59_17660 c3f996248155dd1a9cf5535acc8c636d 101 Gene3D G3DSA:1.20.59.10 1 100 2.2E-30 T 14-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 LH59_17660 c3f996248155dd1a9cf5535acc8c636d 101 SMART SM00830 15 95 7.2E-21 T 14-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 LH59_28235 c9759d0bcf5e8beb906e6d42aa478077 481 PRINTS PR00067 Catalase signature 21 44 8.4E-77 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 LH59_28235 c9759d0bcf5e8beb906e6d42aa478077 481 PRINTS PR00067 Catalase signature 124 142 8.4E-77 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 LH59_28235 c9759d0bcf5e8beb906e6d42aa478077 481 PRINTS PR00067 Catalase signature 321 347 8.4E-77 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 LH59_28235 c9759d0bcf5e8beb906e6d42aa478077 481 PRINTS PR00067 Catalase signature 289 316 8.4E-77 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 LH59_28235 c9759d0bcf5e8beb906e6d42aa478077 481 PRINTS PR00067 Catalase signature 84 102 8.4E-77 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 LH59_28235 c9759d0bcf5e8beb906e6d42aa478077 481 PRINTS PR00067 Catalase signature 105 122 8.4E-77 T 14-10-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 LH59_28235 c9759d0bcf5e8beb906e6d42aa478077 481 Pfam PF00199 Catalase 8 388 5.6E-198 T 14-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 LH59_28235 c9759d0bcf5e8beb906e6d42aa478077 481 SUPERFAMILY SSF56634 3 480 4.84E-222 T 14-10-2018 IPR020835 Catalase superfamily GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 LH59_28235 c9759d0bcf5e8beb906e6d42aa478077 481 ProSitePatterns PS00438 Catalase proximal active site signature. 44 60 - T 14-10-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 LH59_28235 c9759d0bcf5e8beb906e6d42aa478077 481 Gene3D G3DSA:2.40.180.10 3 481 4.8E-238 T 14-10-2018 IPR037060 Catalase core domain superfamily GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 LH59_28235 c9759d0bcf5e8beb906e6d42aa478077 481 SMART SM01060 8 392 1.4E-300 T 14-10-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 LH59_28235 c9759d0bcf5e8beb906e6d42aa478077 481 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 334 342 - T 14-10-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 LH59_28235 c9759d0bcf5e8beb906e6d42aa478077 481 Pfam PF06628 Catalase-related immune-responsive 418 477 1.2E-23 T 14-10-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 LH59_28235 c9759d0bcf5e8beb906e6d42aa478077 481 PIRSF PIRSF038928 1 481 7.6E-230 T 14-10-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695|Reactome: R-HSA-9033241 LH59_03105 27b977babe0882fa4ac13c917c0cbcbd 392 TIGRFAM TIGR04408 LptG_lptG: LPS export ABC transporter permease LptG 4 368 3.2E-89 T 14-10-2018 IPR030923 LPS export ABC transporter permease LptG GO:0043190|GO:0055085 LH59_03105 27b977babe0882fa4ac13c917c0cbcbd 392 Pfam PF03739 Predicted permease YjgP/YjgQ family 6 365 4.0E-63 T 14-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 LH59_13650 6d261673e0f668b912c31bd3310884bf 381 Pfam PF01266 FAD dependent oxidoreductase 8 352 8.3E-46 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 LH59_13650 6d261673e0f668b912c31bd3310884bf 381 Gene3D G3DSA:3.50.50.60 8 352 2.6E-113 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_13650 6d261673e0f668b912c31bd3310884bf 381 Gene3D G3DSA:3.30.9.10 87 312 2.6E-113 T 14-10-2018 LH59_13650 6d261673e0f668b912c31bd3310884bf 381 SUPERFAMILY SSF51905 7 364 1.48E-42 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_24195 e4c7b109bf04ad013a3d7e07a830fc8f 319 Pfam PF03466 LysR substrate binding domain 89 304 2.5E-24 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_24195 e4c7b109bf04ad013a3d7e07a830fc8f 319 SUPERFAMILY SSF53850 90 307 3.62E-20 T 14-10-2018 LH59_24195 e4c7b109bf04ad013a3d7e07a830fc8f 319 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 9.0E-16 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_24195 e4c7b109bf04ad013a3d7e07a830fc8f 319 Gene3D G3DSA:3.40.190.10 94 176 1.2E-7 T 14-10-2018 LH59_24195 e4c7b109bf04ad013a3d7e07a830fc8f 319 Gene3D G3DSA:3.40.190.10 177 269 1.2E-7 T 14-10-2018 LH59_24195 e4c7b109bf04ad013a3d7e07a830fc8f 319 Gene3D G3DSA:1.10.10.10 1 85 4.4E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_24195 e4c7b109bf04ad013a3d7e07a830fc8f 319 SUPERFAMILY SSF46785 2 82 1.13E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_05645 9b043e3532fefb2b47bfabbbda5da413 163 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 76 4.0E-35 T 14-10-2018 LH59_05645 9b043e3532fefb2b47bfabbbda5da413 163 SUPERFAMILY SSF55021 79 162 2.44E-25 T 14-10-2018 LH59_05645 9b043e3532fefb2b47bfabbbda5da413 163 Pfam PF13710 ACT domain 12 73 9.0E-16 T 14-10-2018 LH59_05645 9b043e3532fefb2b47bfabbbda5da413 163 Pfam PF10369 Small subunit of acetolactate synthase 84 157 9.1E-27 T 14-10-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 LH59_05645 9b043e3532fefb2b47bfabbbda5da413 163 SUPERFAMILY SSF55021 1 76 6.87E-23 T 14-10-2018 LH59_05645 9b043e3532fefb2b47bfabbbda5da413 163 Gene3D G3DSA:3.30.70.260 1 78 1.8E-36 T 14-10-2018 LH59_05645 9b043e3532fefb2b47bfabbbda5da413 163 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 1 157 2.7E-64 T 14-10-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 LH59_05645 9b043e3532fefb2b47bfabbbda5da413 163 Gene3D G3DSA:3.30.70.1150 83 163 5.1E-30 T 14-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal LH59_21825 803b8e7037d7436fdde31ec6903e6f98 200 Pfam PF01810 LysE type translocator 13 198 5.2E-40 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 LH59_22995 7d50197d58922cfcdf93072e676e4d84 115 Gene3D G3DSA:3.10.450.40 37 107 1.1E-8 T 14-10-2018 LH59_22995 7d50197d58922cfcdf93072e676e4d84 115 Pfam PF03413 Peptidase propeptide and YPEB domain 52 104 5.6E-8 T 14-10-2018 IPR025711 PepSY domain LH59_17350 0e34a5979084c442f7f5d97ca9fc1a84 193 Gene3D G3DSA:3.20.20.400 4 189 1.2E-45 T 14-10-2018 IPR035928 GlpP-like superfamily LH59_17350 0e34a5979084c442f7f5d97ca9fc1a84 193 SUPERFAMILY SSF110391 13 186 2.22E-46 T 14-10-2018 IPR035928 GlpP-like superfamily LH59_17350 0e34a5979084c442f7f5d97ca9fc1a84 193 PIRSF PIRSF016897 3 191 8.0E-53 T 14-10-2018 IPR006699 Glycerol uptake operon antiterminator GO:0006071|GO:0006355 LH59_17350 0e34a5979084c442f7f5d97ca9fc1a84 193 Pfam PF04309 Glycerol-3-phosphate responsive antiterminator 14 185 1.1E-46 T 14-10-2018 IPR006699 Glycerol uptake operon antiterminator GO:0006071|GO:0006355 LH59_00815 fe460ccf0f754e34dafc2ab2aeadbb53 295 SMART SM00342 206 289 3.5E-29 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_00815 fe460ccf0f754e34dafc2ab2aeadbb53 295 Gene3D G3DSA:1.10.10.60 186 295 7.6E-30 T 14-10-2018 LH59_00815 fe460ccf0f754e34dafc2ab2aeadbb53 295 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 243 285 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 LH59_00815 fe460ccf0f754e34dafc2ab2aeadbb53 295 Pfam PF12833 Helix-turn-helix domain 212 290 7.4E-22 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_00815 fe460ccf0f754e34dafc2ab2aeadbb53 295 SUPERFAMILY SSF46689 193 240 9.86E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_00815 fe460ccf0f754e34dafc2ab2aeadbb53 295 SUPERFAMILY SSF46689 242 293 1.25E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_06565 28ab27c57663e3e6516aad43a0cb12c3 195 SUPERFAMILY SSF50249 10 82 2.23E-11 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_06565 28ab27c57663e3e6516aad43a0cb12c3 195 Hamap MF_00201 DNA repair protein RecO [recO]. 7 192 13.88 T 14-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 LH59_06565 28ab27c57663e3e6516aad43a0cb12c3 195 TIGRFAM TIGR00613 reco: DNA repair protein RecO 15 152 2.0E-18 T 14-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 LH59_06565 28ab27c57663e3e6516aad43a0cb12c3 195 SUPERFAMILY SSF57863 90 148 1.91E-7 T 14-10-2018 IPR037278 ARFGAP/RecO-like zinc finger LH59_06565 28ab27c57663e3e6516aad43a0cb12c3 195 Gene3D G3DSA:2.40.50.140 9 83 2.2E-27 T 14-10-2018 LH59_06565 28ab27c57663e3e6516aad43a0cb12c3 195 Pfam PF11967 Recombination protein O N terminal 11 81 1.7E-18 T 14-10-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal LH59_06565 28ab27c57663e3e6516aad43a0cb12c3 195 Pfam PF02565 Recombination protein O C terminal 87 151 7.7E-16 T 14-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 LH59_06565 28ab27c57663e3e6516aad43a0cb12c3 195 Gene3D G3DSA:1.20.1440.120 85 165 2.0E-23 T 14-10-2018 LH59_16535 d3ab3f893bafcfaae80f16dd358b1412 316 SUPERFAMILY SSF53850 99 289 7.24E-19 T 14-10-2018 LH59_16535 d3ab3f893bafcfaae80f16dd358b1412 316 SUPERFAMILY SSF46785 4 118 3.13E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_16535 d3ab3f893bafcfaae80f16dd358b1412 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 1.4E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_16535 d3ab3f893bafcfaae80f16dd358b1412 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 1.4E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_16535 d3ab3f893bafcfaae80f16dd358b1412 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 1.4E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_16535 d3ab3f893bafcfaae80f16dd358b1412 316 Pfam PF03466 LysR substrate binding domain 95 305 1.6E-21 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_16535 d3ab3f893bafcfaae80f16dd358b1412 316 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 11 69 9.6E-19 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_16535 d3ab3f893bafcfaae80f16dd358b1412 316 Gene3D G3DSA:3.40.190.10 174 275 4.7E-9 T 14-10-2018 LH59_16535 d3ab3f893bafcfaae80f16dd358b1412 316 Gene3D G3DSA:1.10.10.10 9 95 5.1E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_16535 d3ab3f893bafcfaae80f16dd358b1412 316 Gene3D G3DSA:3.40.190.10 162 173 4.7E-9 T 14-10-2018 LH59_19850 716aef0bb8abc9800c89974f80216072 532 Pfam PF15984 Bacterial collagen, middle region 65 184 2.0E-14 T 14-10-2018 IPR031929 Bacterial collagen-like protein, middle domain LH59_19850 716aef0bb8abc9800c89974f80216072 532 Pfam PF15984 Bacterial collagen, middle region 195 344 2.1E-9 T 14-10-2018 IPR031929 Bacterial collagen-like protein, middle domain LH59_01020 0edbfd2956b50158f0147bcb805c747a 353 Gene3D G3DSA:3.20.20.70 2 352 3.2E-110 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_01020 0edbfd2956b50158f0147bcb805c747a 353 Pfam PF03060 Nitronate monooxygenase 3 343 5.0E-82 T 14-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 LH59_01020 0edbfd2956b50158f0147bcb805c747a 353 SUPERFAMILY SSF51412 2 332 1.16E-63 T 14-10-2018 LH59_20360 f55112df835837bdafb33d6147de6bed 735 PIRSF PIRSF036354 1 731 4.4E-294 T 14-10-2018 IPR011399 Nitrous oxide reductase expression regulator NosR GO:0003677|GO:0016020|GO:0045893 LH59_20360 f55112df835837bdafb33d6147de6bed 735 Pfam PF04205 FMN-binding domain 73 152 4.2E-5 T 14-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 LH59_20360 f55112df835837bdafb33d6147de6bed 735 SUPERFAMILY SSF54862 517 684 4.86E-10 T 14-10-2018 LH59_20360 f55112df835837bdafb33d6147de6bed 735 Pfam PF12801 4Fe-4S binding domain 500 546 9.0E-14 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain LH59_20360 f55112df835837bdafb33d6147de6bed 735 Pfam PF12801 4Fe-4S binding domain 602 644 1.1E-5 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain LH59_20360 f55112df835837bdafb33d6147de6bed 735 SMART SM00900 70 159 2.3E-8 T 14-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 LH59_12140 e08b6fe477e1885a49b05628edbadbd8 136 SUPERFAMILY SSF54593 3 132 8.06E-25 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_12140 e08b6fe477e1885a49b05628edbadbd8 136 Gene3D G3DSA:3.10.180.10 2 133 1.5E-41 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_12140 e08b6fe477e1885a49b05628edbadbd8 136 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 128 8.1E-13 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain LH59_07335 23a2e1316b75883c352d6a999c18c957 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 322 8.9E-81 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_07335 23a2e1316b75883c352d6a999c18c957 326 PIRSF PIRSF017082 1 325 2.4E-77 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_07335 23a2e1316b75883c352d6a999c18c957 326 Gene3D G3DSA:3.40.190.150 31 316 7.8E-106 T 14-10-2018 LH59_07335 23a2e1316b75883c352d6a999c18c957 326 Gene3D G3DSA:3.40.190.10 128 251 7.8E-106 T 14-10-2018 LH59_07335 23a2e1316b75883c352d6a999c18c957 326 SUPERFAMILY SSF53850 111 286 6.06E-14 T 14-10-2018 LH59_04335 e3582fcbf4bd742cdba7d485cf06e6f4 108 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 14 94 4.5E-30 T 14-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 LH59_04335 e3582fcbf4bd742cdba7d485cf06e6f4 108 Gene3D G3DSA:3.30.1360.20 6 99 1.7E-36 T 14-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 LH59_04335 e3582fcbf4bd742cdba7d485cf06e6f4 108 SUPERFAMILY SSF55248 14 96 1.06E-31 T 14-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 LH59_04335 e3582fcbf4bd742cdba7d485cf06e6f4 108 Hamap MF_00434 Putative pterin-4-alpha-carbinolamine dehydratase. 1 96 23.174 T 14-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 LH59_23880 64d8fda1bc1488445fb4cd74d2200dfd 388 SMART SM00922 162 259 2.5E-16 T 14-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal LH59_23880 64d8fda1bc1488445fb4cd74d2200dfd 388 Pfam PF13378 Enolase C-terminal domain-like 165 376 9.8E-43 T 14-10-2018 IPR029065 Enolase C-terminal domain-like LH59_23880 64d8fda1bc1488445fb4cd74d2200dfd 388 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 5 134 2.0E-5 T 14-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain LH59_23880 64d8fda1bc1488445fb4cd74d2200dfd 388 SUPERFAMILY SSF54826 1 138 5.79E-31 T 14-10-2018 LH59_23880 64d8fda1bc1488445fb4cd74d2200dfd 388 SUPERFAMILY SSF51604 123 384 1.12E-57 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily LH59_23880 64d8fda1bc1488445fb4cd74d2200dfd 388 Gene3D G3DSA:3.30.390.10 1 127 1.1E-68 T 14-10-2018 IPR029017 Enolase-like, N-terminal LH59_23880 64d8fda1bc1488445fb4cd74d2200dfd 388 Gene3D G3DSA:3.20.20.120 128 388 5.8E-69 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily LH59_25220 5ecf59a870e1d4154783910c39aaeb0b 452 Gene3D G3DSA:1.20.1250.20 30 452 3.2E-57 T 14-10-2018 LH59_25220 5ecf59a870e1d4154783910c39aaeb0b 452 Pfam PF07690 Major Facilitator Superfamily 270 444 1.2E-9 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_25220 5ecf59a870e1d4154783910c39aaeb0b 452 SUPERFAMILY SSF103473 30 449 1.57E-60 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_25220 5ecf59a870e1d4154783910c39aaeb0b 452 Pfam PF00083 Sugar (and other) transporter 37 252 1.1E-24 T 14-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 LH59_09745 7cce243fa3aba571f9228c75e7354e8b 144 SUPERFAMILY SSF55729 8 134 5.73E-29 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_09745 7cce243fa3aba571f9228c75e7354e8b 144 Gene3D G3DSA:3.40.630.30 6 143 2.4E-40 T 14-10-2018 LH59_09745 7cce243fa3aba571f9228c75e7354e8b 144 Pfam PF00583 Acetyltransferase (GNAT) family 30 128 2.0E-18 T 14-10-2018 IPR000182 GNAT domain LH59_23865 8f2faaeee308b9d449ee80b0c4530e3e 116 Pfam PF08883 Dopa 4,5-dioxygenase family 11 111 3.2E-32 T 14-10-2018 IPR014980 Dopa 4,5-dioxygenase LH59_23865 8f2faaeee308b9d449ee80b0c4530e3e 116 PIRSF PIRSF028139 4 116 4.3E-37 T 14-10-2018 IPR014980 Dopa 4,5-dioxygenase LH59_23865 8f2faaeee308b9d449ee80b0c4530e3e 116 Gene3D G3DSA:3.30.70.1240 2 115 7.1E-38 T 14-10-2018 IPR023389 DOPA-like superfamily LH59_23865 8f2faaeee308b9d449ee80b0c4530e3e 116 SUPERFAMILY SSF143410 6 113 3.92E-41 T 14-10-2018 IPR023389 DOPA-like superfamily LH59_16825 47e1abe56b8fcd17bd879a03db265774 105 PRINTS PR00297 10kDa chaperonin signature 60 72 9.0E-32 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 LH59_16825 47e1abe56b8fcd17bd879a03db265774 105 PRINTS PR00297 10kDa chaperonin signature 25 46 9.0E-32 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 LH59_16825 47e1abe56b8fcd17bd879a03db265774 105 PRINTS PR00297 10kDa chaperonin signature 81 94 9.0E-32 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 LH59_16825 47e1abe56b8fcd17bd879a03db265774 105 PRINTS PR00297 10kDa chaperonin signature 3 18 9.0E-32 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 LH59_16825 47e1abe56b8fcd17bd879a03db265774 105 Pfam PF00166 Chaperonin 10 Kd subunit 2 93 4.2E-35 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 LH59_16825 47e1abe56b8fcd17bd879a03db265774 105 ProSitePatterns PS00681 Chaperonins cpn10 signature. 3 27 - T 14-10-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 LH59_16825 47e1abe56b8fcd17bd879a03db265774 105 Gene3D G3DSA:2.30.33.40 1 103 7.0E-37 T 14-10-2018 IPR037124 GroES chaperonin superfamily GO:0005737|GO:0006457 LH59_16825 47e1abe56b8fcd17bd879a03db265774 105 Hamap MF_00580 10 kDa chaperonin [groS]. 2 95 25.552 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 LH59_16825 47e1abe56b8fcd17bd879a03db265774 105 SUPERFAMILY SSF50129 1 94 2.94E-33 T 14-10-2018 IPR011032 GroES-like superfamily LH59_16825 47e1abe56b8fcd17bd879a03db265774 105 SMART SM00883 2 94 8.3E-55 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 LH59_00580 ad66d9dda4f4561f977974002dec67a1 392 SUPERFAMILY SSF55031 181 286 1.44E-27 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain LH59_00580 ad66d9dda4f4561f977974002dec67a1 392 Gene3D G3DSA:3.40.630.10 10 373 5.7E-132 T 14-10-2018 LH59_00580 ad66d9dda4f4561f977974002dec67a1 392 Gene3D G3DSA:3.30.70.360 177 292 5.7E-132 T 14-10-2018 LH59_00580 ad66d9dda4f4561f977974002dec67a1 392 SUPERFAMILY SSF53187 6 390 7.14E-87 T 14-10-2018 LH59_00580 ad66d9dda4f4561f977974002dec67a1 392 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 10 372 1.8E-101 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 LH59_00580 ad66d9dda4f4561f977974002dec67a1 392 Pfam PF07687 Peptidase dimerisation domain 181 279 8.9E-10 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain LH59_00580 ad66d9dda4f4561f977974002dec67a1 392 PIRSF PIRSF005962 2 392 6.4E-124 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 LH59_00580 ad66d9dda4f4561f977974002dec67a1 392 Pfam PF01546 Peptidase family M20/M25/M40 68 351 5.3E-35 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 LH59_12715 8708bc4e527825e09a9995f534951bc3 386 SUPERFAMILY SSF47203 229 384 1.45E-41 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 LH59_12715 8708bc4e527825e09a9995f534951bc3 386 Gene3D G3DSA:2.40.110.10 120 235 5.2E-34 T 14-10-2018 LH59_12715 8708bc4e527825e09a9995f534951bc3 386 SUPERFAMILY SSF56645 5 243 3.8E-62 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 LH59_12715 8708bc4e527825e09a9995f534951bc3 386 Gene3D G3DSA:1.10.540.10 3 115 6.2E-30 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 LH59_12715 8708bc4e527825e09a9995f534951bc3 386 Gene3D G3DSA:1.20.140.10 236 380 6.8E-35 T 14-10-2018 LH59_12715 8708bc4e527825e09a9995f534951bc3 386 PIRSF PIRSF016578 2 195 5.0E-9 T 14-10-2018 LH59_12715 8708bc4e527825e09a9995f534951bc3 386 PIRSF PIRSF016578 236 383 5.0E-6 T 14-10-2018 LH59_12715 8708bc4e527825e09a9995f534951bc3 386 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 364 2.6E-32 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LH59_12715 8708bc4e527825e09a9995f534951bc3 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 115 1.6E-25 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 LH59_12715 8708bc4e527825e09a9995f534951bc3 386 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 120 218 1.1E-21 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 LH59_26670 ada0bf4f3e1e8715399e9bd5dc16f121 290 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 2 286 38.716 T 14-10-2018 IPR005337 RapZ-like family GO:0005524 LH59_26670 ada0bf4f3e1e8715399e9bd5dc16f121 290 Pfam PF03668 P-loop ATPase protein family 3 283 1.1E-84 T 14-10-2018 IPR005337 RapZ-like family GO:0005524 LH59_26670 ada0bf4f3e1e8715399e9bd5dc16f121 290 Gene3D G3DSA:3.40.50.300 2 167 2.0E-7 T 14-10-2018 LH59_26670 ada0bf4f3e1e8715399e9bd5dc16f121 290 PIRSF PIRSF005052 2 289 1.8E-111 T 14-10-2018 IPR005337 RapZ-like family GO:0005524 LH59_26670 ada0bf4f3e1e8715399e9bd5dc16f121 290 SUPERFAMILY SSF52540 3 160 4.22E-12 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_21380 3e77ffc0791d21ba49559278e440a510 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 320 3.6E-92 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_21380 3e77ffc0791d21ba49559278e440a510 324 PIRSF PIRSF017082 1 323 6.8E-80 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_21380 3e77ffc0791d21ba49559278e440a510 324 Gene3D G3DSA:3.40.190.150 29 314 7.4E-118 T 14-10-2018 LH59_21380 3e77ffc0791d21ba49559278e440a510 324 Gene3D G3DSA:3.40.190.10 126 249 7.4E-118 T 14-10-2018 LH59_21380 3e77ffc0791d21ba49559278e440a510 324 SUPERFAMILY SSF53850 113 286 2.79E-11 T 14-10-2018 LH59_20325 2c1aad0d8f5969f3d8167766c396376f 227 Gene3D G3DSA:1.25.40.10 53 206 8.3E-20 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_20325 2c1aad0d8f5969f3d8167766c396376f 227 SUPERFAMILY SSF48452 85 193 1.68E-14 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_20325 2c1aad0d8f5969f3d8167766c396376f 227 SMART SM00028 147 180 4.2E-4 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 LH59_20325 2c1aad0d8f5969f3d8167766c396376f 227 SMART SM00028 113 146 440.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 LH59_02795 a1fbaf96171bcc4bea2f4b69a4cb1d26 425 Gene3D G3DSA:1.10.287.470 128 201 4.2E-92 T 14-10-2018 LH59_02795 a1fbaf96171bcc4bea2f4b69a4cb1d26 425 SUPERFAMILY SSF111369 83 321 1.57E-58 T 14-10-2018 LH59_02795 a1fbaf96171bcc4bea2f4b69a4cb1d26 425 Pfam PF13437 HlyD family secretion protein 205 308 6.9E-6 T 14-10-2018 LH59_02795 a1fbaf96171bcc4bea2f4b69a4cb1d26 425 Gene3D G3DSA:2.40.30.170 82 326 4.2E-92 T 14-10-2018 LH59_02795 a1fbaf96171bcc4bea2f4b69a4cb1d26 425 Pfam PF13533 Biotin-lipoyl like 94 139 3.9E-14 T 14-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain LH59_02795 a1fbaf96171bcc4bea2f4b69a4cb1d26 425 Gene3D G3DSA:2.40.420.20 327 395 4.2E-92 T 14-10-2018 LH59_02795 a1fbaf96171bcc4bea2f4b69a4cb1d26 425 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 83 397 6.1E-75 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 LH59_02795 a1fbaf96171bcc4bea2f4b69a4cb1d26 425 Gene3D G3DSA:2.40.50.100 93 237 4.2E-92 T 14-10-2018 LH59_21515 80bdd9e74dde808105aeac251243ecab 220 Pfam PF04390 Lipopolysaccharide-assembly 43 170 4.9E-8 T 14-10-2018 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 LH59_21515 80bdd9e74dde808105aeac251243ecab 220 Gene3D G3DSA:3.30.160.150 44 182 4.1E-39 T 14-10-2018 LH59_21515 80bdd9e74dde808105aeac251243ecab 220 Hamap MF_01186 LPS-assembly lipoprotein LptE [lptE]. 16 175 23.412 T 14-10-2018 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 LH59_14070 6300a38ce1dac676d0aabfb3ea7017d1 187 SMART SM00382 10 181 1.7E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_14070 6300a38ce1dac676d0aabfb3ea7017d1 187 Gene3D G3DSA:3.40.50.300 1 187 8.1E-46 T 14-10-2018 LH59_14070 6300a38ce1dac676d0aabfb3ea7017d1 187 Pfam PF00005 ABC transporter 2 133 2.4E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_14070 6300a38ce1dac676d0aabfb3ea7017d1 187 SUPERFAMILY SSF52540 3 183 3.14E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_22935 af10fc8b418fe36a5a98c5e12c56ad2d 85 Pfam PF11390 NADH-dependant formate dehydrogenase delta subunit FdsD 5 71 3.4E-27 T 14-10-2018 IPR021074 Formate dehydrogenase, delta subunit LH59_07705 cf69d621dbdd95de7bca15e06d456370 553 Pfam PF02690 Na+/Pi-cotransporter 163 241 5.7E-11 T 14-10-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 LH59_07705 cf69d621dbdd95de7bca15e06d456370 553 Pfam PF02690 Na+/Pi-cotransporter 16 150 3.5E-34 T 14-10-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 LH59_07705 cf69d621dbdd95de7bca15e06d456370 553 SUPERFAMILY SSF109755 332 543 1.57E-21 T 14-10-2018 LH59_07705 cf69d621dbdd95de7bca15e06d456370 553 Gene3D G3DSA:1.20.58.220 335 542 1.6E-5 T 14-10-2018 IPR038078 PhoU-like domain superfamily LH59_07705 cf69d621dbdd95de7bca15e06d456370 553 TIGRFAM TIGR00704 NaPi_cotrn_rel: Na/Pi-cotransporter II-related protein 5 307 4.4E-64 T 14-10-2018 IPR004633 Na/Pi-cotransporter II-related/YqeW-like protein GO:0016020 LH59_00695 27df5e8b740a23207e9d6fa212439b74 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 319 1.9E-69 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_00695 27df5e8b740a23207e9d6fa212439b74 325 SUPERFAMILY SSF53850 115 287 3.41E-13 T 14-10-2018 LH59_00695 27df5e8b740a23207e9d6fa212439b74 325 Gene3D G3DSA:3.40.190.10 126 250 2.1E-94 T 14-10-2018 LH59_00695 27df5e8b740a23207e9d6fa212439b74 325 Gene3D G3DSA:3.40.190.150 30 315 2.1E-94 T 14-10-2018 LH59_00695 27df5e8b740a23207e9d6fa212439b74 325 PIRSF PIRSF017082 1 324 5.0E-75 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_16740 24b9204d2240eccbb6bb531793d5f6b2 485 Gene3D G3DSA:3.40.720.10 5 460 3.7E-110 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 LH59_16740 24b9204d2240eccbb6bb531793d5f6b2 485 SUPERFAMILY SSF53649 4 437 1.74E-102 T 14-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 LH59_16740 24b9204d2240eccbb6bb531793d5f6b2 485 Pfam PF00884 Sulfatase 6 345 1.3E-49 T 14-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 LH59_22535 0db5ab4a9d3b564019903c90af650eb3 161 Gene3D G3DSA:3.40.630.30 11 153 2.8E-29 T 14-10-2018 LH59_22535 0db5ab4a9d3b564019903c90af650eb3 161 SUPERFAMILY SSF55729 12 141 1.57E-28 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_22535 0db5ab4a9d3b564019903c90af650eb3 161 Pfam PF00583 Acetyltransferase (GNAT) family 49 140 1.1E-17 T 14-10-2018 IPR000182 GNAT domain LH59_09735 4b4f1aea4b5057df7199bb0b7b0d61dc 101 Pfam PF07978 NIPSNAP 6 99 5.0E-26 T 14-10-2018 IPR012577 NIPSNAP LH59_09735 4b4f1aea4b5057df7199bb0b7b0d61dc 101 SUPERFAMILY SSF54909 1 99 5.37E-23 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel LH59_09735 4b4f1aea4b5057df7199bb0b7b0d61dc 101 Gene3D G3DSA:3.30.70.100 6 95 4.9E-7 T 14-10-2018 LH59_09475 725311eefd1563d6cb8f99021d45d05c 197 SUPERFAMILY SSF160904 10 190 9.94E-44 T 14-10-2018 LH59_09475 725311eefd1563d6cb8f99021d45d05c 197 Pfam PF07336 Putative stress-induced transcription regulator 17 143 5.6E-19 T 14-10-2018 IPR010852 Putative stress-induced transcription regulator LH59_09475 725311eefd1563d6cb8f99021d45d05c 197 Gene3D G3DSA:1.10.3300.10 14 192 9.4E-28 T 14-10-2018 IPR023286 ABATE domain superfamily LH59_09475 725311eefd1563d6cb8f99021d45d05c 197 Pfam PF11706 CGNR zinc finger 149 191 9.6E-18 T 14-10-2018 IPR021005 Zinc finger, CGNR LH59_24815 901efe86e0d9c8d923ca9dfda2410ee3 957 SUPERFAMILY SSF53383 479 951 5.98E-98 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_24815 901efe86e0d9c8d923ca9dfda2410ee3 957 SUPERFAMILY SSF53383 14 437 1.35E-104 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_24815 901efe86e0d9c8d923ca9dfda2410ee3 957 Pfam PF02347 Glycine cleavage system P-protein 14 435 2.5E-179 T 14-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 LH59_24815 901efe86e0d9c8d923ca9dfda2410ee3 957 Pfam PF02347 Glycine cleavage system P-protein 448 733 3.9E-13 T 14-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 LH59_24815 901efe86e0d9c8d923ca9dfda2410ee3 957 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 14 950 0.0 T 14-10-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 LH59_24815 901efe86e0d9c8d923ca9dfda2410ee3 957 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 5 956 25.403 T 14-10-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 LH59_24815 901efe86e0d9c8d923ca9dfda2410ee3 957 Gene3D G3DSA:3.90.1150.10 764 904 1.1E-42 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_24815 901efe86e0d9c8d923ca9dfda2410ee3 957 Gene3D G3DSA:3.40.640.10 522 744 1.8E-58 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_24815 901efe86e0d9c8d923ca9dfda2410ee3 957 Gene3D G3DSA:3.40.640.10 92 349 2.3E-107 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_10870 a0eef79d2238c1a846859c71f04bccd9 462 SUPERFAMILY SSF75304 21 456 1.44E-121 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_10870 a0eef79d2238c1a846859c71f04bccd9 462 Gene3D G3DSA:3.90.1300.10 22 458 2.2E-135 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_10870 a0eef79d2238c1a846859c71f04bccd9 462 Pfam PF01425 Amidase 40 248 5.3E-83 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_10870 a0eef79d2238c1a846859c71f04bccd9 462 Pfam PF01425 Amidase 276 450 4.9E-17 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_25610 cf4a138ca69d4784c507b228a80bc0b4 112 Pfam PF05939 Phage minor tail protein 4 110 8.5E-29 T 14-10-2018 IPR010265 Bacteriophage lambda, GpM, minor tail LH59_03145 2e521794064c139440ef101a97834c56 223 Gene3D G3DSA:1.10.10.10 122 221 1.6E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_03145 2e521794064c139440ef101a97834c56 223 Pfam PF00072 Response regulator receiver domain 3 112 2.7E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_03145 2e521794064c139440ef101a97834c56 223 Gene3D G3DSA:3.40.50.2300 1 121 2.6E-34 T 14-10-2018 LH59_03145 2e521794064c139440ef101a97834c56 223 SMART SM00862 145 217 2.2E-17 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_03145 2e521794064c139440ef101a97834c56 223 SMART SM00448 1 112 1.6E-36 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_03145 2e521794064c139440ef101a97834c56 223 SUPERFAMILY SSF52172 1 162 6.4E-38 T 14-10-2018 IPR011006 CheY-like superfamily LH59_03145 2e521794064c139440ef101a97834c56 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 216 1.2E-16 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_11850 b5d644b266c240163f22fad5cf0fedd7 260 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_11850 b5d644b266c240163f22fad5cf0fedd7 260 Gene3D G3DSA:3.40.50.300 5 257 9.3E-76 T 14-10-2018 LH59_11850 b5d644b266c240163f22fad5cf0fedd7 260 SUPERFAMILY SSF52540 9 248 5.56E-74 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_11850 b5d644b266c240163f22fad5cf0fedd7 260 Pfam PF00005 ABC transporter 25 178 4.9E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_11850 b5d644b266c240163f22fad5cf0fedd7 260 PIRSF PIRSF039085 6 254 1.4E-109 T 14-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 LH59_11850 b5d644b266c240163f22fad5cf0fedd7 260 SMART SM00382 34 226 1.8E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_00790 0f1f4ff7e3bc2b25fdf58fd8f40f5304 308 SUPERFAMILY SSF161098 92 288 2.49E-23 T 14-10-2018 IPR035906 MetI-like superfamily LH59_00790 0f1f4ff7e3bc2b25fdf58fd8f40f5304 308 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 16 67 1.3E-9 T 14-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain LH59_00790 0f1f4ff7e3bc2b25fdf58fd8f40f5304 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 308 1.6E-25 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_00790 0f1f4ff7e3bc2b25fdf58fd8f40f5304 308 Gene3D G3DSA:1.10.3720.10 86 305 2.8E-22 T 14-10-2018 IPR035906 MetI-like superfamily LH59_13630 c61f7e4e73055a9ceb69e5aa8c64f72e 311 SUPERFAMILY SSF161098 90 295 5.45E-16 T 14-10-2018 IPR035906 MetI-like superfamily LH59_13630 c61f7e4e73055a9ceb69e5aa8c64f72e 311 Gene3D G3DSA:1.10.3720.10 83 304 7.3E-22 T 14-10-2018 IPR035906 MetI-like superfamily LH59_13630 c61f7e4e73055a9ceb69e5aa8c64f72e 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 311 1.5E-39 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_24980 719e481cb8744875608811594c65848a 355 Gene3D G3DSA:1.10.287.470 81 111 1.0E-9 T 14-10-2018 LH59_24980 719e481cb8744875608811594c65848a 355 Gene3D G3DSA:2.40.50.100 47 80 1.0E-9 T 14-10-2018 LH59_24980 719e481cb8744875608811594c65848a 355 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 46 300 3.8E-14 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain LH59_24980 719e481cb8744875608811594c65848a 355 Gene3D G3DSA:1.10.287.470 112 182 4.9E-7 T 14-10-2018 LH59_24980 719e481cb8744875608811594c65848a 355 Gene3D G3DSA:2.40.30.170 227 336 6.9E-13 T 14-10-2018 LH59_24980 719e481cb8744875608811594c65848a 355 SUPERFAMILY SSF111369 173 299 1.16E-6 T 14-10-2018 LH59_24980 719e481cb8744875608811594c65848a 355 SUPERFAMILY SSF111369 41 104 2.22E-7 T 14-10-2018 LH59_06025 9bad56086ff93d50b5c505f22b6ca6b0 476 Gene3D G3DSA:1.20.1600.10 58 469 5.9E-129 T 14-10-2018 LH59_06025 9bad56086ff93d50b5c505f22b6ca6b0 476 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 18 468 2.9E-95 T 14-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 LH59_06025 9bad56086ff93d50b5c505f22b6ca6b0 476 Pfam PF02321 Outer membrane efflux protein 287 466 3.8E-23 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 LH59_06025 9bad56086ff93d50b5c505f22b6ca6b0 476 Pfam PF02321 Outer membrane efflux protein 68 257 1.0E-27 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 LH59_06025 9bad56086ff93d50b5c505f22b6ca6b0 476 SUPERFAMILY SSF56954 8 470 2.88E-103 T 14-10-2018 LH59_06025 9bad56086ff93d50b5c505f22b6ca6b0 476 Gene3D G3DSA:2.20.200.10 105 357 5.9E-129 T 14-10-2018 LH59_09215 60193da28e8efa4d9775134747a6b855 385 PIRSF PIRSF001549 5 345 7.3E-30 T 14-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 LH59_09215 60193da28e8efa4d9775134747a6b855 385 Pfam PF13393 Histidyl-tRNA synthetase 10 316 1.0E-109 T 14-10-2018 LH59_09215 60193da28e8efa4d9775134747a6b855 385 SUPERFAMILY SSF55681 4 319 2.61E-51 T 14-10-2018 LH59_09215 60193da28e8efa4d9775134747a6b855 385 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 16 367 33.878 T 14-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 LH59_09215 60193da28e8efa4d9775134747a6b855 385 Gene3D G3DSA:3.30.930.10 4 328 3.9E-59 T 14-10-2018 LH59_18360 dcfc6934bec0b2b7979166238fb98925 248 SUPERFAMILY SSF53850 34 233 4.77E-30 T 14-10-2018 LH59_18360 dcfc6934bec0b2b7979166238fb98925 248 SMART SM00062 16 239 2.0E-19 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_18360 dcfc6934bec0b2b7979166238fb98925 248 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 34 232 6.3E-20 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_18360 dcfc6934bec0b2b7979166238fb98925 248 Gene3D G3DSA:3.40.190.10 103 195 2.1E-21 T 14-10-2018 LH59_18360 dcfc6934bec0b2b7979166238fb98925 248 Gene3D G3DSA:3.40.190.10 16 227 2.1E-21 T 14-10-2018 LH59_12735 392dcd4cb64222ac532a5af7a2e79ea3 407 SMART SM00729 31 248 3.0E-48 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 LH59_12735 392dcd4cb64222ac532a5af7a2e79ea3 407 Pfam PF04055 Radical SAM superfamily 36 200 2.0E-16 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 LH59_12735 392dcd4cb64222ac532a5af7a2e79ea3 407 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 33 378 4.5E-102 T 14-10-2018 IPR004559 Oxygen-independent coproporphyrinogen III oxidase-like GO:0004109|GO:0005737|GO:0006779|GO:0055114 LH59_12735 392dcd4cb64222ac532a5af7a2e79ea3 407 SUPERFAMILY SSF102114 23 407 2.22E-106 T 14-10-2018 LH59_12735 392dcd4cb64222ac532a5af7a2e79ea3 407 Gene3D G3DSA:3.80.30.20 13 322 1.2E-92 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe LH59_12735 392dcd4cb64222ac532a5af7a2e79ea3 407 Pfam PF06969 HemN C-terminal domain 335 396 2.1E-12 T 14-10-2018 IPR010723 HemN, C-terminal LH59_01775 f627b71cf908b8a05f56a0f4fc6259d6 673 SUPERFAMILY SSF53649 280 610 1.7E-20 T 14-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 LH59_01775 f627b71cf908b8a05f56a0f4fc6259d6 673 Gene3D G3DSA:3.40.720.10 268 578 1.5E-24 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 LH59_01775 f627b71cf908b8a05f56a0f4fc6259d6 673 Pfam PF00884 Sulfatase 282 569 4.5E-12 T 14-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 LH59_15575 c2accb17e265948bc63e1ea82be55feb 263 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 169 187 - T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 LH59_15575 c2accb17e265948bc63e1ea82be55feb 263 Gene3D G3DSA:3.90.230.10 3 254 1.5E-109 T 14-10-2018 LH59_15575 c2accb17e265948bc63e1ea82be55feb 263 SUPERFAMILY SSF55920 6 255 6.67E-95 T 14-10-2018 IPR036005 Creatinase/aminopeptidase-like LH59_15575 c2accb17e265948bc63e1ea82be55feb 263 Hamap MF_01974 Methionine aminopeptidase [map]. 5 252 41.031 T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 LH59_15575 c2accb17e265948bc63e1ea82be55feb 263 Pfam PF00557 Metallopeptidase family M24 15 243 5.5E-56 T 14-10-2018 IPR000994 Peptidase M24 LH59_15575 c2accb17e265948bc63e1ea82be55feb 263 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 6 251 4.6E-97 T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 LH59_15575 c2accb17e265948bc63e1ea82be55feb 263 PRINTS PR00599 Methionine aminopeptidase-1 signature 93 109 1.9E-22 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 LH59_15575 c2accb17e265948bc63e1ea82be55feb 263 PRINTS PR00599 Methionine aminopeptidase-1 signature 163 175 1.9E-22 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 LH59_15575 c2accb17e265948bc63e1ea82be55feb 263 PRINTS PR00599 Methionine aminopeptidase-1 signature 194 206 1.9E-22 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 LH59_15575 c2accb17e265948bc63e1ea82be55feb 263 PRINTS PR00599 Methionine aminopeptidase-1 signature 71 84 1.9E-22 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 LH59_22960 6ceb839d63206b87661d85af7ee398ce 192 Pfam PF02417 Chromate transporter 21 178 2.2E-29 T 14-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 LH59_17790 84287fea428fbe6d2fa3702603fe3c71 314 Gene3D G3DSA:3.30.1780.10 6 308 5.3E-89 T 14-10-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 LH59_17790 84287fea428fbe6d2fa3702603fe3c71 314 Gene3D G3DSA:3.40.50.720 121 293 5.3E-89 T 14-10-2018 LH59_17790 84287fea428fbe6d2fa3702603fe3c71 314 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 6 311 4.4E-70 T 14-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 LH59_17790 84287fea428fbe6d2fa3702603fe3c71 314 SUPERFAMILY SSF51735 1 309 1.22E-92 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_17790 84287fea428fbe6d2fa3702603fe3c71 314 PIRSF PIRSF001439 1 313 8.2E-72 T 14-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 LH59_02500 dd4c30d2edcdca10bbbc74da99e4b5c2 517 Hamap MF_00414 Probable protein kinase UbiB [ubiB]. 1 517 49.602 T 14-10-2018 IPR010232 Probable protein kinase UbiB GO:0006744 LH59_02500 dd4c30d2edcdca10bbbc74da99e4b5c2 517 TIGRFAM TIGR01982 UbiB: 2-polyprenylphenol 6-hydroxylase 4 442 3.9E-171 T 14-10-2018 IPR010232 Probable protein kinase UbiB GO:0006744 LH59_02500 dd4c30d2edcdca10bbbc74da99e4b5c2 517 SUPERFAMILY SSF56112 90 435 3.43E-42 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily LH59_02500 dd4c30d2edcdca10bbbc74da99e4b5c2 517 Pfam PF03109 ABC1 family 108 229 4.9E-33 T 14-10-2018 IPR004147 UbiB domain LH59_01530 1bb5f68fc8d046b87823c5b0d704ef66 243 Gene3D G3DSA:1.20.910.10 1 236 1.5E-58 T 14-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 LH59_01530 1bb5f68fc8d046b87823c5b0d704ef66 243 Pfam PF14518 Iron-containing redox enzyme 44 215 4.0E-36 T 14-10-2018 LH59_01530 1bb5f68fc8d046b87823c5b0d704ef66 243 SUPERFAMILY SSF48613 9 226 3.89E-51 T 14-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 LH59_01530 1bb5f68fc8d046b87823c5b0d704ef66 243 SMART SM01236 78 181 6.8E-27 T 14-10-2018 LH59_21680 dd4e874f43c9b58f9762e903623da123 236 Pfam PF14497 Glutathione S-transferase, C-terminal domain 110 216 1.5E-26 T 14-10-2018 IPR004046 Glutathione S-transferase, C-terminal LH59_21680 dd4e874f43c9b58f9762e903623da123 236 SUPERFAMILY SSF47616 106 221 2.51E-20 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily LH59_21680 dd4e874f43c9b58f9762e903623da123 236 Gene3D G3DSA:3.40.30.10 3 234 1.2E-92 T 14-10-2018 LH59_21680 dd4e874f43c9b58f9762e903623da123 236 Gene3D G3DSA:1.20.1050.10 87 206 1.2E-92 T 14-10-2018 LH59_21680 dd4e874f43c9b58f9762e903623da123 236 SUPERFAMILY SSF52833 1 84 4.54E-17 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_09080 c7818736ac35b250c368f77bc5938dff 446 Pfam PF13416 Bacterial extracellular solute-binding protein 55 370 4.7E-30 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein LH59_09080 c7818736ac35b250c368f77bc5938dff 446 Gene3D G3DSA:3.40.190.10 156 437 8.1E-82 T 14-10-2018 LH59_09080 c7818736ac35b250c368f77bc5938dff 446 Gene3D G3DSA:3.40.190.10 41 397 8.1E-82 T 14-10-2018 LH59_09080 c7818736ac35b250c368f77bc5938dff 446 SUPERFAMILY SSF53850 37 439 6.29E-46 T 14-10-2018 LH59_16585 4f893d6687085aa319aee040897ed6fc 452 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 344 441 2.8E-14 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_16585 4f893d6687085aa319aee040897ed6fc 452 PRINTS PR00344 Bacterial sensor protein C-terminal signature 377 391 1.3E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_16585 4f893d6687085aa319aee040897ed6fc 452 PRINTS PR00344 Bacterial sensor protein C-terminal signature 409 427 1.3E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_16585 4f893d6687085aa319aee040897ed6fc 452 PRINTS PR00344 Bacterial sensor protein C-terminal signature 395 405 1.3E-8 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_16585 4f893d6687085aa319aee040897ed6fc 452 SUPERFAMILY SSF47384 213 293 1.16E-13 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 LH59_16585 4f893d6687085aa319aee040897ed6fc 452 SMART SM00388 229 294 2.2E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_16585 4f893d6687085aa319aee040897ed6fc 452 SMART SM00387 339 450 3.1E-25 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_16585 4f893d6687085aa319aee040897ed6fc 452 SUPERFAMILY SSF55874 300 447 1.7E-26 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_16585 4f893d6687085aa319aee040897ed6fc 452 Gene3D G3DSA:3.30.565.10 300 449 1.4E-25 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_16585 4f893d6687085aa319aee040897ed6fc 452 Pfam PF00512 His Kinase A (phospho-acceptor) domain 231 293 3.1E-10 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_16585 4f893d6687085aa319aee040897ed6fc 452 Gene3D G3DSA:1.10.287.130 180 294 2.9E-18 T 14-10-2018 LH59_27840 99bb3f38a11a59f79027610bf051cf89 256 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 228 248 2.1E-5 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal LH59_27840 99bb3f38a11a59f79027610bf051cf89 256 Gene3D G3DSA:3.40.50.300 1 249 1.2E-57 T 14-10-2018 LH59_27840 99bb3f38a11a59f79027610bf051cf89 256 Pfam PF00005 ABC transporter 18 177 8.1E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_27840 99bb3f38a11a59f79027610bf051cf89 256 SMART SM00382 26 226 6.6E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_27840 99bb3f38a11a59f79027610bf051cf89 256 SUPERFAMILY SSF52540 2 247 2.36E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_16485 0e0f9a0392af3caf8b84ff67850377d5 222 SUPERFAMILY SSF53335 36 192 7.26E-30 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_16485 0e0f9a0392af3caf8b84ff67850377d5 222 Gene3D G3DSA:3.40.50.150 31 211 4.5E-40 T 14-10-2018 LH59_16485 0e0f9a0392af3caf8b84ff67850377d5 222 Pfam PF13578 Methyltransferase domain 85 188 7.3E-15 T 14-10-2018 LH59_19055 7b0079d192cdf6be0dd08a8853f43bc5 109 Gene3D G3DSA:1.20.1270.360 2 109 5.4E-31 T 14-10-2018 LH59_06030 3c1e5d2df422fa17f065bd96a5d936cd 220 Pfam PF13814 Replication-relaxation 22 94 8.6E-6 T 14-10-2018 IPR025855 Plasmid replication-relaxation LH59_06030 3c1e5d2df422fa17f065bd96a5d936cd 220 ProSitePatterns PS00261 Glycoprotein hormones beta chain signature 1. 178 184 - T 14-10-2018 IPR018245 Gonadotropin, beta subunit, conserved site GO:0005179|GO:0005576 LH59_06030 3c1e5d2df422fa17f065bd96a5d936cd 220 Gene3D G3DSA:1.10.10.10 13 120 3.3E-10 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_06030 3c1e5d2df422fa17f065bd96a5d936cd 220 SUPERFAMILY SSF46785 20 197 3.02E-33 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_07780 132befaf5fc30d3d5e36df2de8f2b445 284 Gene3D G3DSA:1.10.10.10 40 114 5.0E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_07780 132befaf5fc30d3d5e36df2de8f2b445 284 Pfam PF09339 IclR helix-turn-helix domain 47 98 7.8E-15 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_07780 132befaf5fc30d3d5e36df2de8f2b445 284 SUPERFAMILY SSF55781 117 279 4.51E-31 T 14-10-2018 LH59_07780 132befaf5fc30d3d5e36df2de8f2b445 284 Gene3D G3DSA:3.30.450.40 119 280 1.3E-30 T 14-10-2018 IPR029016 GAF-like domain superfamily LH59_07780 132befaf5fc30d3d5e36df2de8f2b445 284 Pfam PF01614 Bacterial transcriptional regulator 177 275 1.2E-8 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal LH59_07780 132befaf5fc30d3d5e36df2de8f2b445 284 SMART SM00346 45 135 2.8E-17 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_07780 132befaf5fc30d3d5e36df2de8f2b445 284 SUPERFAMILY SSF46785 45 117 4.53E-12 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_21210 cd5b2bf89eb4841db6e1f89a896849c7 495 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 14 487 2.5E-125 T 14-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 LH59_21210 cd5b2bf89eb4841db6e1f89a896849c7 495 Pfam PF02321 Outer membrane efflux protein 86 276 9.4E-23 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 LH59_21210 cd5b2bf89eb4841db6e1f89a896849c7 495 Pfam PF02321 Outer membrane efflux protein 305 485 1.6E-29 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 LH59_21210 cd5b2bf89eb4841db6e1f89a896849c7 495 Gene3D G3DSA:2.20.200.10 123 376 2.0E-144 T 14-10-2018 LH59_21210 cd5b2bf89eb4841db6e1f89a896849c7 495 PIRSF PIRSF001892 4 492 2.5E-58 T 14-10-2018 IPR028351 Cyclolysin transport protein CyaE GO:0005215 LH59_21210 cd5b2bf89eb4841db6e1f89a896849c7 495 SUPERFAMILY SSF56954 3 490 6.15E-117 T 14-10-2018 LH59_21210 cd5b2bf89eb4841db6e1f89a896849c7 495 Gene3D G3DSA:1.20.1600.10 77 488 2.0E-144 T 14-10-2018 LH59_23165 c446e8edd0c160207034a68296ebc433 160 Pfam PF04461 Protein of unknown function (DUF520) 2 159 2.0E-59 T 14-10-2018 IPR007551 Protein of unknown function DUF520 LH59_23165 c446e8edd0c160207034a68296ebc433 160 Gene3D G3DSA:3.30.70.860 95 160 1.2E-28 T 14-10-2018 IPR035571 UPF0234-like, C-terminal LH59_23165 c446e8edd0c160207034a68296ebc433 160 SUPERFAMILY SSF89963 89 160 3.79E-27 T 14-10-2018 IPR036183 YajQ-like superfamily LH59_23165 c446e8edd0c160207034a68296ebc433 160 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 1 160 27.745 T 14-10-2018 IPR007551 Protein of unknown function DUF520 LH59_23165 c446e8edd0c160207034a68296ebc433 160 SUPERFAMILY SSF89963 2 83 4.71E-28 T 14-10-2018 IPR036183 YajQ-like superfamily LH59_23165 c446e8edd0c160207034a68296ebc433 160 Gene3D G3DSA:3.30.70.990 9 94 1.2E-27 T 14-10-2018 IPR035570 UPF0234, N-terminal LH59_27200 eccc8fead8310fcef83ef051ec979b5b 101 Gene3D G3DSA:2.40.50.320 30 101 1.7E-21 T 14-10-2018 LH59_27200 eccc8fead8310fcef83ef051ec979b5b 101 Pfam PF11604 Copper binding periplasmic protein CusF 36 100 2.9E-24 T 14-10-2018 IPR021647 Copper binding periplasmic protein CusF LH59_26975 65974b57ed4830440a63a1c4d95a30bb 63 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 33 46 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 LH59_26975 65974b57ed4830440a63a1c4d95a30bb 63 Gene3D G3DSA:3.30.420.40 32 62 2.0E-11 T 14-10-2018 LH59_26975 65974b57ed4830440a63a1c4d95a30bb 63 Pfam PF00012 Hsp70 protein 1 59 6.6E-24 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LH59_26975 65974b57ed4830440a63a1c4d95a30bb 63 Gene3D G3DSA:3.30.420.40 1 31 2.7E-7 T 14-10-2018 LH59_26975 65974b57ed4830440a63a1c4d95a30bb 63 SUPERFAMILY SSF53067 1 60 1.3E-10 T 14-10-2018 LH59_25620 15e18cd0e3e4927adcc7adc9d4fdf247 96 Pfam PF13227 Protein of unknown function (DUF4035) 30 76 6.0E-8 T 14-10-2018 IPR025116 Protein of unknown function DUF4035 LH59_16510 d471961ee08d797f9ccb5add8be59275 551 Pfam PF03865 Haemolysin secretion/activation protein ShlB/FhaC/HecB 201 512 1.6E-29 T 14-10-2018 IPR005565 Haemolysin activator HlyB, C-terminal LH59_16510 d471961ee08d797f9ccb5add8be59275 551 Pfam PF08479 POTRA domain, ShlB-type 63 138 9.6E-19 T 14-10-2018 IPR013686 Polypeptide-transport-associated, ShlB-type LH59_16510 d471961ee08d797f9ccb5add8be59275 551 Gene3D G3DSA:3.10.20.310 53 138 3.9E-14 T 14-10-2018 LH59_16510 d471961ee08d797f9ccb5add8be59275 551 Gene3D G3DSA:2.40.160.50 172 551 9.7E-79 T 14-10-2018 LH59_04425 a20e2a3fe50c2da9603162bf0b6e582c 242 SMART SM00563 71 186 3.9E-30 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 LH59_04425 a20e2a3fe50c2da9603162bf0b6e582c 242 Pfam PF01553 Acyltransferase 59 183 7.3E-20 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 LH59_04425 a20e2a3fe50c2da9603162bf0b6e582c 242 SUPERFAMILY SSF69593 3 239 2.75E-39 T 14-10-2018 LH59_16245 8382118bdcf6ebbfabd4d622744f78fc 452 Pfam PF04775 Acyl-CoA thioester hydrolase/BAAT N-terminal region 15 134 2.6E-31 T 14-10-2018 IPR006862 Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase LH59_16245 8382118bdcf6ebbfabd4d622744f78fc 452 Pfam PF08840 BAAT / Acyl-CoA thioester hydrolase C terminal 199 427 8.9E-57 T 14-10-2018 IPR014940 BAAT/Acyl-CoA thioester hydrolase C-terminal LH59_16245 8382118bdcf6ebbfabd4d622744f78fc 452 Gene3D G3DSA:2.60.40.2240 1 124 7.6E-28 T 14-10-2018 LH59_16245 8382118bdcf6ebbfabd4d622744f78fc 452 Gene3D G3DSA:3.40.50.1820 125 427 1.1E-62 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_16245 8382118bdcf6ebbfabd4d622744f78fc 452 SUPERFAMILY SSF53474 62 428 3.42E-31 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_16245 8382118bdcf6ebbfabd4d622744f78fc 452 PIRSF PIRSF016521 1 434 4.5E-104 T 14-10-2018 IPR016662 Acyl-CoA thioesterase, long chain GO:0006637|GO:0016790 LH59_08010 b890f41fa33aa7564794e84607138c00 239 Pfam PF03741 Integral membrane protein TerC family 14 190 7.8E-44 T 14-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 LH59_08010 b890f41fa33aa7564794e84607138c00 239 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 12 191 1.6E-71 T 14-10-2018 IPR022301 Integral membrane protein YjbE LH59_27445 941278bd2a0e2046a9bb2287e0410b98 625 Pfam PF13537 Glutamine amidotransferase domain 47 167 7.3E-49 T 14-10-2018 IPR017932 Glutamine amidotransferase type 2 domain LH59_27445 941278bd2a0e2046a9bb2287e0410b98 625 SUPERFAMILY SSF56235 2 225 2.23E-66 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal LH59_27445 941278bd2a0e2046a9bb2287e0410b98 625 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 555 4.9E-137 T 14-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 LH59_27445 941278bd2a0e2046a9bb2287e0410b98 625 SUPERFAMILY SSF52402 234 613 6.09E-70 T 14-10-2018 LH59_27445 941278bd2a0e2046a9bb2287e0410b98 625 Gene3D G3DSA:3.60.20.10 3 185 1.4E-67 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal LH59_27445 941278bd2a0e2046a9bb2287e0410b98 625 Pfam PF00733 Asparagine synthase 243 616 7.9E-99 T 14-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 LH59_27445 941278bd2a0e2046a9bb2287e0410b98 625 PIRSF PIRSF001589 1 625 3.0E-155 T 14-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 LH59_21245 8ace95b0dd4df9fda9911df79549d898 228 Pfam PF00005 ABC transporter 27 168 3.5E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_21245 8ace95b0dd4df9fda9911df79549d898 228 SMART SM00382 27 218 1.3E-18 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_21245 8ace95b0dd4df9fda9911df79549d898 228 Gene3D G3DSA:3.40.50.300 7 225 7.5E-58 T 14-10-2018 LH59_21245 8ace95b0dd4df9fda9911df79549d898 228 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_21245 8ace95b0dd4df9fda9911df79549d898 228 SUPERFAMILY SSF52540 18 222 1.18E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_24890 b0a324e3bfa6c4e0093201ac287b6178 362 Hamap MF_02040 Iron-sulfur cluster carrier protein. 91 339 37.447 T 14-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein LH59_24890 b0a324e3bfa6c4e0093201ac287b6178 362 Pfam PF01883 Iron-sulfur cluster assembly protein 6 77 1.8E-13 T 14-10-2018 IPR002744 MIP18 family-like LH59_24890 b0a324e3bfa6c4e0093201ac287b6178 362 SUPERFAMILY SSF52540 89 323 9.55E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_24890 b0a324e3bfa6c4e0093201ac287b6178 362 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 95 338 1.1E-101 T 14-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 LH59_24890 b0a324e3bfa6c4e0093201ac287b6178 362 Gene3D G3DSA:3.40.50.300 84 337 7.6E-85 T 14-10-2018 LH59_24890 b0a324e3bfa6c4e0093201ac287b6178 362 ProSitePatterns PS01215 Mrp family signature. 202 218 - T 14-10-2018 IPR000808 Mrp, conserved site GO:0005524 LH59_24890 b0a324e3bfa6c4e0093201ac287b6178 362 SUPERFAMILY SSF117916 5 84 4.25E-9 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily LH59_02080 bb92bb93d7c457d2965d1e5d932bbfc2 326 Gene3D G3DSA:3.30.60.70 118 158 5.1E-19 T 14-10-2018 IPR038361 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain superfamily KEGG: 00300+2.3.1.117 LH59_02080 bb92bb93d7c457d2965d1e5d932bbfc2 326 TIGRFAM TIGR03535 DapD_actino: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 8 324 7.2E-144 T 14-10-2018 IPR019875 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, actinobacteria KEGG: 00300+2.3.1.117 LH59_02080 bb92bb93d7c457d2965d1e5d932bbfc2 326 Gene3D G3DSA:2.160.10.10 159 325 4.1E-67 T 14-10-2018 LH59_02080 bb92bb93d7c457d2965d1e5d932bbfc2 326 SUPERFAMILY SSF51161 79 305 3.6E-38 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily LH59_02080 bb92bb93d7c457d2965d1e5d932bbfc2 326 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 240 272 1.6E-15 T 14-10-2018 IPR001451 Hexapeptide repeat LH59_02080 bb92bb93d7c457d2965d1e5d932bbfc2 326 Gene3D G3DSA:3.30.70.2010 2 117 2.3E-40 T 14-10-2018 LH59_02080 bb92bb93d7c457d2965d1e5d932bbfc2 326 Pfam PF14789 Tetrahydrodipicolinate N-succinyltransferase middle 118 158 6.6E-16 T 14-10-2018 IPR032784 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain KEGG: 00300+2.3.1.117 LH59_02080 bb92bb93d7c457d2965d1e5d932bbfc2 326 Hamap MF_02122 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 6 323 42.576 T 14-10-2018 IPR026586 Type 2 tetrahydrodipicolinate N-succinyltransferase family GO:0008666 KEGG: 00300+2.3.1.117 LH59_07690 e470a10cbfea2ae01f93861878030cf3 279 Pfam PF02535 ZIP Zinc transporter 91 250 2.9E-23 T 14-10-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 LH59_04085 812d104986ce08c23de662abc09789a1 327 Pfam PF01551 Peptidase family M23 209 303 1.3E-34 T 14-10-2018 IPR016047 Peptidase M23 LH59_04085 812d104986ce08c23de662abc09789a1 327 Gene3D G3DSA:2.70.70.10 148 311 1.2E-50 T 14-10-2018 IPR011055 Duplicated hybrid motif LH59_04085 812d104986ce08c23de662abc09789a1 327 SUPERFAMILY SSF51261 166 307 1.73E-57 T 14-10-2018 IPR011055 Duplicated hybrid motif LH59_14570 dc876ad4feeae6574a25727c734a8b1c 393 Gene3D G3DSA:3.50.50.60 5 343 7.1E-82 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_14570 dc876ad4feeae6574a25727c734a8b1c 393 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 1.3E-17 T 14-10-2018 LH59_14570 dc876ad4feeae6574a25727c734a8b1c 393 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 278 293 1.3E-17 T 14-10-2018 LH59_14570 dc876ad4feeae6574a25727c734a8b1c 393 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 309 1.3E-17 T 14-10-2018 LH59_14570 dc876ad4feeae6574a25727c734a8b1c 393 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 148 163 1.3E-17 T 14-10-2018 LH59_14570 dc876ad4feeae6574a25727c734a8b1c 393 Pfam PF01494 FAD binding domain 2 339 6.0E-20 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 LH59_14570 dc876ad4feeae6574a25727c734a8b1c 393 Gene3D G3DSA:3.30.9.30 37 270 7.1E-82 T 14-10-2018 LH59_14570 dc876ad4feeae6574a25727c734a8b1c 393 SUPERFAMILY SSF51905 1 371 4.65E-56 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_22200 3bb729a901125b8c86771b7ea91d9e81 328 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 33 309 4.1E-28 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 LH59_22200 3bb729a901125b8c86771b7ea91d9e81 328 Gene3D G3DSA:3.40.190.170 25 327 6.1E-64 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily LH59_11655 04b0c7931b5d6b3dc41e1d9fb4a321d7 238 PIRSF PIRSF005650 1 238 2.5E-91 T 14-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 LH59_11655 04b0c7931b5d6b3dc41e1d9fb4a321d7 238 Hamap MF_01220_B Uridylate kinase [pyrH]. 4 237 44.284 T 14-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 LH59_11655 04b0c7931b5d6b3dc41e1d9fb4a321d7 238 SUPERFAMILY SSF53633 5 237 8.9E-70 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily LH59_11655 04b0c7931b5d6b3dc41e1d9fb4a321d7 238 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 6 237 4.2E-100 T 14-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 LH59_11655 04b0c7931b5d6b3dc41e1d9fb4a321d7 238 Gene3D G3DSA:3.40.1160.10 1 238 1.4E-76 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily LH59_11655 04b0c7931b5d6b3dc41e1d9fb4a321d7 238 Pfam PF00696 Amino acid kinase family 7 216 6.9E-28 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 LH59_17715 ba836cb1e613ebbcda89b27d520fdb9d 329 Gene3D G3DSA:3.40.190.10 130 252 8.0E-97 T 14-10-2018 LH59_17715 ba836cb1e613ebbcda89b27d520fdb9d 329 PIRSF PIRSF017082 1 328 1.3E-74 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_17715 ba836cb1e613ebbcda89b27d520fdb9d 329 Gene3D G3DSA:3.40.190.150 32 318 8.0E-97 T 14-10-2018 LH59_17715 ba836cb1e613ebbcda89b27d520fdb9d 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 324 4.5E-69 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_17715 ba836cb1e613ebbcda89b27d520fdb9d 329 SUPERFAMILY SSF53850 119 287 1.85E-10 T 14-10-2018 LH59_11245 8adb308af6e78e9639833767241a4175 902 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 12 901 0.0 T 14-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 LH59_11245 8adb308af6e78e9639833767241a4175 902 SUPERFAMILY SSF52518 64 477 2.28E-135 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold LH59_11245 8adb308af6e78e9639833767241a4175 902 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 147 302 7.4E-9 T 14-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 LH59_11245 8adb308af6e78e9639833767241a4175 902 SUPERFAMILY SSF52922 715 901 5.65E-59 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 LH59_11245 8adb308af6e78e9639833767241a4175 902 Gene3D G3DSA:3.40.50.970 63 481 1.2E-131 T 14-10-2018 LH59_11245 8adb308af6e78e9639833767241a4175 902 Gene3D G3DSA:3.40.50.970 482 717 6.0E-107 T 14-10-2018 LH59_11245 8adb308af6e78e9639833767241a4175 902 Gene3D G3DSA:3.40.50.920 718 902 5.5E-75 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 LH59_11245 8adb308af6e78e9639833767241a4175 902 PIRSF PIRSF000156 4 902 0.0 T 14-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 LH59_11245 8adb308af6e78e9639833767241a4175 902 SUPERFAMILY SSF52518 483 711 9.25E-97 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold LH59_18965 acf434956191f869bec8c07859b07855 331 PIRSF PIRSF018266 10 331 5.4E-55 T 14-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component LH59_18965 acf434956191f869bec8c07859b07855 331 Pfam PF16220 Domain of unknown function (DUF4880) 20 60 1.8E-10 T 14-10-2018 IPR032623 FecR, N-terminal LH59_18965 acf434956191f869bec8c07859b07855 331 Pfam PF04773 FecR protein 120 218 9.3E-8 T 14-10-2018 IPR006860 FecR protein LH59_18815 9e71d89861d3361e5e3fc5aa267490b8 438 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 12 425 6.7E-91 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit LH59_18815 9e71d89861d3361e5e3fc5aa267490b8 438 PIRSF PIRSF006066 4 438 3.7E-94 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 LH59_18815 9e71d89861d3361e5e3fc5aa267490b8 438 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 21 432 3.8E-88 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 LH59_05495 3f4a9370ebdd5c0972a0c29149f5f248 333 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_05495 3f4a9370ebdd5c0972a0c29149f5f248 333 SUPERFAMILY SSF52540 47 310 6.32E-78 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_05495 3f4a9370ebdd5c0972a0c29149f5f248 333 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 239 323 6.7E-24 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_05495 3f4a9370ebdd5c0972a0c29149f5f248 333 Pfam PF00005 ABC transporter 39 188 1.2E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_05495 3f4a9370ebdd5c0972a0c29149f5f248 333 SMART SM00382 47 238 4.7E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_05495 3f4a9370ebdd5c0972a0c29149f5f248 333 Gene3D G3DSA:3.40.50.300 12 330 1.9E-102 T 14-10-2018 LH59_05495 3f4a9370ebdd5c0972a0c29149f5f248 333 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 240 305 2.1E-17 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_10695 3d6b57d91663fbb83e47f604bee534ec 247 Gene3D G3DSA:1.10.10.10 5 74 1.0E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_10695 3d6b57d91663fbb83e47f604bee534ec 247 SUPERFAMILY SSF64288 65 242 8.95E-22 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily LH59_10695 3d6b57d91663fbb83e47f604bee534ec 247 SMART SM00866 102 238 1.0E-6 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LH59_10695 3d6b57d91663fbb83e47f604bee534ec 247 Pfam PF07702 UTRA domain 128 233 2.5E-11 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LH59_10695 3d6b57d91663fbb83e47f604bee534ec 247 SMART SM00345 18 77 1.7E-16 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_10695 3d6b57d91663fbb83e47f604bee534ec 247 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 77 3.1E-19 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_10695 3d6b57d91663fbb83e47f604bee534ec 247 Gene3D G3DSA:3.40.1410.10 75 230 3.7E-16 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily LH59_10695 3d6b57d91663fbb83e47f604bee534ec 247 SUPERFAMILY SSF46785 9 79 9.98E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_10695 3d6b57d91663fbb83e47f604bee534ec 247 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 7.0E-8 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_10695 3d6b57d91663fbb83e47f604bee534ec 247 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 7.0E-8 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_22030 f5a0ea4c5abab707935851df0beb0fd9 200 SUPERFAMILY SSF48613 5 183 2.92E-35 T 14-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 LH59_22030 f5a0ea4c5abab707935851df0beb0fd9 200 Gene3D G3DSA:1.20.910.10 2 194 4.5E-45 T 14-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 LH59_22030 f5a0ea4c5abab707935851df0beb0fd9 200 Pfam PF01126 Heme oxygenase 7 182 4.5E-6 T 14-10-2018 IPR016053 Haem oxygenase-like GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 LH59_27785 7f05c17ab6b7e14dc581b025602ea05d 101 SUPERFAMILY SSF57716 2 101 3.85E-39 T 14-10-2018 LH59_27785 7f05c17ab6b7e14dc581b025602ea05d 101 Gene3D G3DSA:4.10.830.10 39 101 2.1E-25 T 14-10-2018 LH59_27785 7f05c17ab6b7e14dc581b025602ea05d 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 27.559 T 14-10-2018 IPR023036 Ribosomal protein S14, bacterial/plastid LH59_27785 7f05c17ab6b7e14dc581b025602ea05d 101 Pfam PF00253 Ribosomal protein S14p/S29e 47 100 1.1E-28 T 14-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_09820 1ec1e57d1e2d48ef5a66848adb02aa3e 292 Gene3D G3DSA:3.40.630.40 1 285 1.0E-109 T 14-10-2018 LH59_09820 1ec1e57d1e2d48ef5a66848adb02aa3e 292 SUPERFAMILY SSF53187 9 282 4.19E-84 T 14-10-2018 LH59_09820 1ec1e57d1e2d48ef5a66848adb02aa3e 292 Pfam PF05013 N-formylglutamate amidohydrolase 20 252 9.6E-65 T 14-10-2018 IPR007709 N-formylglutamate amidohydrolase LH59_01920 79fef5f95619193d77f4bc84eaf0da3c 345 Pfam PF00795 Carbon-nitrogen hydrolase 15 268 2.8E-47 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 LH59_01920 79fef5f95619193d77f4bc84eaf0da3c 345 SUPERFAMILY SSF56317 13 275 4.19E-54 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily LH59_01920 79fef5f95619193d77f4bc84eaf0da3c 345 Gene3D G3DSA:3.60.110.10 1 345 3.3E-148 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily LH59_22855 2bbbb80bc94aede262a8133dfac8ada8 167 Pfam PF08534 Redoxin 4 164 2.5E-35 T 14-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 LH59_22855 2bbbb80bc94aede262a8133dfac8ada8 167 SUPERFAMILY SSF52833 1 165 1.16E-32 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_22855 2bbbb80bc94aede262a8133dfac8ada8 167 Gene3D G3DSA:3.40.30.10 1 167 6.2E-58 T 14-10-2018 LH59_20770 6e037fd896d1a559d9574e48f17f5a18 318 PRINTS PR00207 Flagellin signature 37 54 9.9E-28 T 14-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 LH59_20770 6e037fd896d1a559d9574e48f17f5a18 318 PRINTS PR00207 Flagellin signature 111 134 9.9E-28 T 14-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 LH59_20770 6e037fd896d1a559d9574e48f17f5a18 318 PRINTS PR00207 Flagellin signature 76 95 9.9E-28 T 14-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 LH59_20770 6e037fd896d1a559d9574e48f17f5a18 318 SUPERFAMILY SSF64518 1 318 1.02E-96 T 14-10-2018 LH59_20770 6e037fd896d1a559d9574e48f17f5a18 318 Gene3D G3DSA:1.20.58.1830 2 56 1.3E-10 T 14-10-2018 LH59_20770 6e037fd896d1a559d9574e48f17f5a18 318 Gene3D G3DSA:1.10.8.410 271 318 4.0E-24 T 14-10-2018 LH59_20770 6e037fd896d1a559d9574e48f17f5a18 318 Pfam PF00700 Bacterial flagellin C-terminal helical region 233 317 3.2E-28 T 14-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 LH59_20770 6e037fd896d1a559d9574e48f17f5a18 318 Pfam PF00669 Bacterial flagellin N-terminal helical region 5 141 4.7E-44 T 14-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 LH59_04380 c633ad8d4374855cbd2f3d943144cd02 263 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 5 253 3.6E-82 T 14-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 LH59_04380 c633ad8d4374855cbd2f3d943144cd02 263 SMART SM00650 20 188 1.9E-80 T 14-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 LH59_04380 c633ad8d4374855cbd2f3d943144cd02 263 Pfam PF00398 Ribosomal RNA adenine dimethylase 4 252 5.9E-58 T 14-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm LH59_04380 c633ad8d4374855cbd2f3d943144cd02 263 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 4 255 54.226 T 14-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 LH59_04380 c633ad8d4374855cbd2f3d943144cd02 263 Gene3D G3DSA:1.10.8.100 194 259 2.3E-19 T 14-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 LH59_04380 c633ad8d4374855cbd2f3d943144cd02 263 Gene3D G3DSA:3.40.50.150 1 187 6.7E-63 T 14-10-2018 LH59_04380 c633ad8d4374855cbd2f3d943144cd02 263 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 36 63 - T 14-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 LH59_04380 c633ad8d4374855cbd2f3d943144cd02 263 SUPERFAMILY SSF53335 4 256 2.46E-73 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_08840 714c73ab11d0e85fd1c5f78198906cfd 446 PRINTS PR00173 Glutamate-aspartate symporter signature 337 356 1.8E-26 T 14-10-2018 LH59_08840 714c73ab11d0e85fd1c5f78198906cfd 446 PRINTS PR00173 Glutamate-aspartate symporter signature 302 328 1.8E-26 T 14-10-2018 LH59_08840 714c73ab11d0e85fd1c5f78198906cfd 446 PRINTS PR00173 Glutamate-aspartate symporter signature 84 109 1.8E-26 T 14-10-2018 LH59_08840 714c73ab11d0e85fd1c5f78198906cfd 446 PRINTS PR00173 Glutamate-aspartate symporter signature 17 37 1.8E-26 T 14-10-2018 LH59_08840 714c73ab11d0e85fd1c5f78198906cfd 446 PRINTS PR00173 Glutamate-aspartate symporter signature 155 177 1.8E-26 T 14-10-2018 LH59_08840 714c73ab11d0e85fd1c5f78198906cfd 446 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 305 328 - T 14-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site LH59_08840 714c73ab11d0e85fd1c5f78198906cfd 446 SUPERFAMILY SSF118215 19 412 1.18E-118 T 14-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 LH59_08840 714c73ab11d0e85fd1c5f78198906cfd 446 Pfam PF00375 Sodium:dicarboxylate symporter family 19 411 2.7E-108 T 14-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 LH59_08840 714c73ab11d0e85fd1c5f78198906cfd 446 Gene3D G3DSA:1.10.3860.10 10 427 7.6E-125 T 14-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 LH59_08840 714c73ab11d0e85fd1c5f78198906cfd 446 Hamap MF_01300 C4-dicarboxylate transport protein [dctA]. 12 438 38.311 T 14-10-2018 IPR023954 C4-dicarboxylate transport protein GO:0006835|GO:0015293|GO:0016021 LH59_08840 714c73ab11d0e85fd1c5f78198906cfd 446 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 46 61 - T 14-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site LH59_11730 1a266eaa6774e3cb344b7a30be67f8b8 275 Pfam PF03618 Kinase/pyrophosphorylase 10 267 3.4E-79 T 14-10-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 LH59_11730 1a266eaa6774e3cb344b7a30be67f8b8 275 Hamap MF_01062 Phosphoenolpyruvate synthase regulatory protein [ppsR]. 7 275 74.86 T 14-10-2018 IPR026530 Phosphoenolpyruvate synthase regulatory protein LH59_19015 4639d191c00416d1d4c2d107ee20b79b 217 SUPERFAMILY SSF52540 2 163 6.54E-12 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_19015 4639d191c00416d1d4c2d107ee20b79b 217 Gene3D G3DSA:3.40.50.300 1 208 8.5E-17 T 14-10-2018 LH59_19015 4639d191c00416d1d4c2d107ee20b79b 217 Pfam PF13671 AAA domain 7 134 7.1E-7 T 14-10-2018 LH59_16035 da9e6f3cfd2d9d96524258d8b6d22236 193 TIGRFAM TIGR03566 FMN_reduc_MsuE: FMN reductase 6 177 1.3E-77 T 14-10-2018 IPR019912 FMN reductase, MsuE-like LH59_16035 da9e6f3cfd2d9d96524258d8b6d22236 193 Pfam PF03358 NADPH-dependent FMN reductase 6 150 7.4E-30 T 14-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 LH59_16035 da9e6f3cfd2d9d96524258d8b6d22236 193 Gene3D G3DSA:3.40.50.360 3 179 2.4E-42 T 14-10-2018 IPR029039 Flavoprotein-like superfamily LH59_16035 da9e6f3cfd2d9d96524258d8b6d22236 193 SUPERFAMILY SSF52218 1 182 7.3E-35 T 14-10-2018 IPR029039 Flavoprotein-like superfamily LH59_14630 e071219341369edb04aa560b23ce779d 254 Pfam PF13353 4Fe-4S single cluster domain 51 126 1.5E-7 T 14-10-2018 LH59_14630 e071219341369edb04aa560b23ce779d 254 SUPERFAMILY SSF102114 50 245 2.35E-25 T 14-10-2018 LH59_14630 e071219341369edb04aa560b23ce779d 254 Gene3D G3DSA:3.20.20.70 37 223 7.1E-31 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_14630 e071219341369edb04aa560b23ce779d 254 Pfam PF04055 Radical SAM superfamily 58 202 4.2E-15 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 LH59_14630 e071219341369edb04aa560b23ce779d 254 TIGRFAM TIGR02495 NrdG2: anaerobic ribonucleoside-triphosphate reductase activating protein 39 224 4.1E-54 T 14-10-2018 IPR012840 Anaerobic ribonucleoside-triphosphate reductase activating protein LH59_14100 5bae6960ed2d9f1375f91a6ff28374f1 304 SUPERFAMILY SSF46689 258 303 1.03E-6 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_14100 5bae6960ed2d9f1375f91a6ff28374f1 304 SMART SM00342 222 304 7.1E-27 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_14100 5bae6960ed2d9f1375f91a6ff28374f1 304 Pfam PF12833 Helix-turn-helix domain 228 303 2.7E-19 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_14100 5bae6960ed2d9f1375f91a6ff28374f1 304 Gene3D G3DSA:1.10.10.60 201 304 9.6E-22 T 14-10-2018 LH59_14100 5bae6960ed2d9f1375f91a6ff28374f1 304 SUPERFAMILY SSF46689 206 256 1.08E-5 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_25625 0e1c77bc6df3d66132863b10746fdbe5 157 Pfam PF06222 Phage tail assembly chaperone 15 146 1.4E-28 T 14-10-2018 IPR010411 Phage tail assembly chaperone Gp13-like LH59_25625 0e1c77bc6df3d66132863b10746fdbe5 157 Gene3D G3DSA:3.30.2220.20 10 149 1.8E-37 T 14-10-2018 IPR038556 Tail assembly chaperone Gp13-like superfamily LH59_22555 5d43140459580dc8b0781636b3318f0b 800 Pfam PF11339 Protein of unknown function (DUF3141) 26 603 9.4E-294 T 14-10-2018 IPR024501 Protein of unknown function DUF3141 LH59_22555 5d43140459580dc8b0781636b3318f0b 800 SUPERFAMILY SSF53474 55 380 1.93E-24 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_10220 a760a5cf5a4a52301b5d2d445eb052ca 111 SUPERFAMILY SSF52833 4 104 1.38E-15 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_10220 a760a5cf5a4a52301b5d2d445eb052ca 111 Pfam PF00085 Thioredoxin 6 98 2.9E-5 T 14-10-2018 IPR013766 Thioredoxin domain GO:0045454 LH59_10220 a760a5cf5a4a52301b5d2d445eb052ca 111 Gene3D G3DSA:3.40.30.10 2 100 2.0E-7 T 14-10-2018 LH59_21065 caeb1831cd63e71cb7610f34c6ebc521 324 SUPERFAMILY SSF53850 73 282 2.99E-11 T 14-10-2018 LH59_21065 caeb1831cd63e71cb7610f34c6ebc521 324 Gene3D G3DSA:3.40.190.10 126 249 2.7E-107 T 14-10-2018 LH59_21065 caeb1831cd63e71cb7610f34c6ebc521 324 Gene3D G3DSA:3.40.190.150 30 314 2.7E-107 T 14-10-2018 LH59_21065 caeb1831cd63e71cb7610f34c6ebc521 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 320 2.3E-81 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_21065 caeb1831cd63e71cb7610f34c6ebc521 324 PIRSF PIRSF017082 1 323 2.9E-82 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_25970 b779fe877327c4f840e6fb917ca66aec 122 Pfam PF07769 psiF repeat 89 121 6.1E-18 T 14-10-2018 IPR011690 Phosphate-starvation-induced PsiF repeat LH59_25970 b779fe877327c4f840e6fb917ca66aec 122 Pfam PF07769 psiF repeat 47 78 3.0E-15 T 14-10-2018 IPR011690 Phosphate-starvation-induced PsiF repeat LH59_00795 1c1a158fe72e059c08b547ab9bcf148c 323 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 319 3.9E-39 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_00795 1c1a158fe72e059c08b547ab9bcf148c 323 Gene3D G3DSA:1.10.3720.10 85 314 5.5E-22 T 14-10-2018 IPR035906 MetI-like superfamily LH59_00795 1c1a158fe72e059c08b547ab9bcf148c 323 SUPERFAMILY SSF161098 92 305 2.07E-18 T 14-10-2018 IPR035906 MetI-like superfamily LH59_05990 384bbe5591916304fba8e6ac7fefeea6 506 Gene3D G3DSA:2.20.200.10 117 368 6.3E-100 T 14-10-2018 LH59_05990 384bbe5591916304fba8e6ac7fefeea6 506 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 18 478 5.8E-98 T 14-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 LH59_05990 384bbe5591916304fba8e6ac7fefeea6 506 SUPERFAMILY SSF56954 6 478 2.62E-85 T 14-10-2018 LH59_05990 384bbe5591916304fba8e6ac7fefeea6 506 Pfam PF02321 Outer membrane efflux protein 297 477 2.5E-21 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 LH59_05990 384bbe5591916304fba8e6ac7fefeea6 506 Pfam PF02321 Outer membrane efflux protein 79 269 3.0E-18 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 LH59_05990 384bbe5591916304fba8e6ac7fefeea6 506 Gene3D G3DSA:1.20.1600.10 69 477 6.3E-100 T 14-10-2018 LH59_25675 e9391daf9e769f9f341759f45417ecbf 1033 SUPERFAMILY SSF69360 70 128 1.14E-6 T 14-10-2018 LH59_25675 e9391daf9e769f9f341759f45417ecbf 1033 Pfam PF14903 WG containing repeat 942 973 9.1E-6 T 14-10-2018 IPR032774 WG containing repeat LH59_25675 e9391daf9e769f9f341759f45417ecbf 1033 Pfam PF14903 WG containing repeat 106 135 1.5E-6 T 14-10-2018 IPR032774 WG containing repeat LH59_25675 e9391daf9e769f9f341759f45417ecbf 1033 Pfam PF14903 WG containing repeat 676 692 0.0021 T 14-10-2018 IPR032774 WG containing repeat LH59_25675 e9391daf9e769f9f341759f45417ecbf 1033 Pfam PF14903 WG containing repeat 903 934 0.23 T 14-10-2018 IPR032774 WG containing repeat LH59_25675 e9391daf9e769f9f341759f45417ecbf 1033 Pfam PF14903 WG containing repeat 72 106 3.8E-12 T 14-10-2018 IPR032774 WG containing repeat LH59_25675 e9391daf9e769f9f341759f45417ecbf 1033 Pfam PF14903 WG containing repeat 563 591 0.091 T 14-10-2018 IPR032774 WG containing repeat LH59_25675 e9391daf9e769f9f341759f45417ecbf 1033 Pfam PF14903 WG containing repeat 651 676 0.15 T 14-10-2018 IPR032774 WG containing repeat LH59_17225 72386c26f74004a2e553c6692aeaf548 432 Pfam PF06689 ClpX C4-type zinc finger 13 50 4.7E-19 T 14-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 LH59_17225 72386c26f74004a2e553c6692aeaf548 432 Gene3D G3DSA:3.40.50.300 57 314 4.0E-108 T 14-10-2018 LH59_17225 72386c26f74004a2e553c6692aeaf548 432 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 6 414 52.17 T 14-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 LH59_17225 72386c26f74004a2e553c6692aeaf548 432 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 9 411 6.0E-198 T 14-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 LH59_17225 72386c26f74004a2e553c6692aeaf548 432 Gene3D G3DSA:3.30.50.30 3 52 1.1E-23 T 14-10-2018 IPR038366 Zinc finger, ClpX C4-type superfamily LH59_17225 72386c26f74004a2e553c6692aeaf548 432 SUPERFAMILY SSF52540 62 397 3.8E-72 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_17225 72386c26f74004a2e553c6692aeaf548 432 SMART SM00382 112 332 8.8E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_17225 72386c26f74004a2e553c6692aeaf548 432 SMART SM00994 12 51 1.7E-23 T 14-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 LH59_17225 72386c26f74004a2e553c6692aeaf548 432 SUPERFAMILY SSF57716 13 48 3.85E-11 T 14-10-2018 LH59_17225 72386c26f74004a2e553c6692aeaf548 432 Pfam PF07724 AAA domain (Cdc48 subfamily) 113 309 3.2E-47 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 LH59_17225 72386c26f74004a2e553c6692aeaf548 432 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 316 393 4.8E-17 T 14-10-2018 IPR019489 Clp ATPase, C-terminal LH59_17225 72386c26f74004a2e553c6692aeaf548 432 Gene3D G3DSA:1.10.8.60 315 422 2.6E-37 T 14-10-2018 LH59_17225 72386c26f74004a2e553c6692aeaf548 432 SMART SM01086 316 411 2.4E-33 T 14-10-2018 IPR019489 Clp ATPase, C-terminal LH59_03385 b8b9eb534078d813d1a70abbc1dc9483 123 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 104 121 - T 14-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 LH59_03385 b8b9eb534078d813d1a70abbc1dc9483 123 Pfam PF01521 Iron-sulphur cluster biosynthesis 19 118 1.1E-20 T 14-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 LH59_03385 b8b9eb534078d813d1a70abbc1dc9483 123 Gene3D G3DSA:2.60.300.12 17 123 1.2E-34 T 14-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 LH59_03385 b8b9eb534078d813d1a70abbc1dc9483 123 Hamap MF_01380 Iron-sulfur cluster insertion protein ErpA [erpA]. 1 123 37.466 T 14-10-2018 IPR023063 FeS cluster insertion protein ErpA GO:0097428 LH59_03385 b8b9eb534078d813d1a70abbc1dc9483 123 SUPERFAMILY SSF89360 15 109 1.9E-31 T 14-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 LH59_03385 b8b9eb534078d813d1a70abbc1dc9483 123 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 20 123 6.6E-39 T 14-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 LH59_07570 70ffc754e250c5b0d973e66e7b86d553 488 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 64 483 6.6E-147 T 14-10-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 LH59_07570 70ffc754e250c5b0d973e66e7b86d553 488 Gene3D G3DSA:2.30.42.10 403 485 4.2E-18 T 14-10-2018 LH59_07570 70ffc754e250c5b0d973e66e7b86d553 488 SMART SM00228 292 374 5.0E-14 T 14-10-2018 IPR001478 PDZ domain GO:0005515 LH59_07570 70ffc754e250c5b0d973e66e7b86d553 488 SMART SM00228 403 478 4.0E-10 T 14-10-2018 IPR001478 PDZ domain GO:0005515 LH59_07570 70ffc754e250c5b0d973e66e7b86d553 488 PRINTS PR00834 HtrA/DegQ protease family signature 224 241 3.0E-47 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 LH59_07570 70ffc754e250c5b0d973e66e7b86d553 488 PRINTS PR00834 HtrA/DegQ protease family signature 246 263 3.0E-47 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 LH59_07570 70ffc754e250c5b0d973e66e7b86d553 488 PRINTS PR00834 HtrA/DegQ protease family signature 190 214 3.0E-47 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 LH59_07570 70ffc754e250c5b0d973e66e7b86d553 488 PRINTS PR00834 HtrA/DegQ protease family signature 150 170 3.0E-47 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 LH59_07570 70ffc754e250c5b0d973e66e7b86d553 488 PRINTS PR00834 HtrA/DegQ protease family signature 332 344 3.0E-47 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 LH59_07570 70ffc754e250c5b0d973e66e7b86d553 488 PRINTS PR00834 HtrA/DegQ protease family signature 129 141 3.0E-47 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 LH59_07570 70ffc754e250c5b0d973e66e7b86d553 488 Pfam PF13365 Trypsin-like peptidase domain 120 253 1.9E-34 T 14-10-2018 LH59_07570 70ffc754e250c5b0d973e66e7b86d553 488 Gene3D G3DSA:2.30.42.10 287 393 1.2E-26 T 14-10-2018 LH59_07570 70ffc754e250c5b0d973e66e7b86d553 488 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 399 475 2.2E-9 T 14-10-2018 IPR001478 PDZ domain GO:0005515 LH59_07570 70ffc754e250c5b0d973e66e7b86d553 488 SUPERFAMILY SSF50156 403 487 6.97E-17 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 LH59_07570 70ffc754e250c5b0d973e66e7b86d553 488 SUPERFAMILY SSF50494 47 301 2.36E-62 T 14-10-2018 IPR009003 Peptidase S1, PA clan LH59_07570 70ffc754e250c5b0d973e66e7b86d553 488 Gene3D G3DSA:2.40.10.120 62 286 3.5E-78 T 14-10-2018 LH59_07570 70ffc754e250c5b0d973e66e7b86d553 488 SUPERFAMILY SSF50156 273 382 1.6E-22 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 LH59_07570 70ffc754e250c5b0d973e66e7b86d553 488 Pfam PF13180 PDZ domain 293 380 1.1E-15 T 14-10-2018 IPR001478 PDZ domain GO:0005515 LH59_13095 a30d3091ec9c99321dfb0f6cd04fe902 373 Gene3D G3DSA:3.20.20.70 21 371 2.6E-155 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_13095 a30d3091ec9c99321dfb0f6cd04fe902 373 PIRSF PIRSF001361 14 373 7.0E-160 T 14-10-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 LH59_13095 a30d3091ec9c99321dfb0f6cd04fe902 373 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 26 370 5.1E-153 T 14-10-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 LH59_13095 a30d3091ec9c99321dfb0f6cd04fe902 373 SUPERFAMILY SSF51569 27 369 2.2E-131 T 14-10-2018 LH59_13095 a30d3091ec9c99321dfb0f6cd04fe902 373 Pfam PF00793 DAHP synthetase I family 60 355 6.2E-99 T 14-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 LH59_10725 96c9639a4eec4a167b0a70540cd0e79b 291 Pfam PF01965 DJ-1/PfpI family 1 170 2.8E-25 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 LH59_10725 96c9639a4eec4a167b0a70540cd0e79b 291 Gene3D G3DSA:3.40.50.880 1 207 1.1E-64 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_10725 96c9639a4eec4a167b0a70540cd0e79b 291 Pfam PF00165 Bacterial regulatory helix-turn-helix proteins, AraC family 219 259 6.5E-11 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_10725 96c9639a4eec4a167b0a70540cd0e79b 291 SUPERFAMILY SSF46689 213 260 9.86E-8 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_10725 96c9639a4eec4a167b0a70540cd0e79b 291 Gene3D G3DSA:1.10.10.60 208 289 2.7E-12 T 14-10-2018 LH59_10725 96c9639a4eec4a167b0a70540cd0e79b 291 SUPERFAMILY SSF52317 1 191 1.28E-49 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_00670 e8b9ab0e04a7fccff2205968135726a3 351 SUPERFAMILY SSF52540 4 243 1.31E-84 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_00670 e8b9ab0e04a7fccff2205968135726a3 351 Gene3D G3DSA:2.40.50.140 285 330 6.4E-12 T 14-10-2018 LH59_00670 e8b9ab0e04a7fccff2205968135726a3 351 Gene3D G3DSA:3.40.50.300 1 238 2.3E-80 T 14-10-2018 LH59_00670 e8b9ab0e04a7fccff2205968135726a3 351 SUPERFAMILY SSF50331 236 345 3.4E-22 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal LH59_00670 e8b9ab0e04a7fccff2205968135726a3 351 Pfam PF00005 ABC transporter 20 161 3.8E-35 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_00670 e8b9ab0e04a7fccff2205968135726a3 351 Gene3D G3DSA:2.40.50.100 267 342 6.4E-12 T 14-10-2018 LH59_00670 e8b9ab0e04a7fccff2205968135726a3 351 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_00670 e8b9ab0e04a7fccff2205968135726a3 351 Pfam PF08402 TOBE domain 271 339 1.7E-14 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 LH59_00670 e8b9ab0e04a7fccff2205968135726a3 351 SMART SM00382 28 211 3.1E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_25755 9cdb0c84bfd292883c29d44002191919 275 Pfam PF09339 IclR helix-turn-helix domain 26 75 1.8E-14 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_25755 9cdb0c84bfd292883c29d44002191919 275 SMART SM00346 24 114 3.0E-22 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_25755 9cdb0c84bfd292883c29d44002191919 275 Pfam PF01614 Bacterial transcriptional regulator 144 267 5.8E-30 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal LH59_25755 9cdb0c84bfd292883c29d44002191919 275 SUPERFAMILY SSF55781 95 267 4.32E-46 T 14-10-2018 LH59_25755 9cdb0c84bfd292883c29d44002191919 275 Gene3D G3DSA:1.10.10.10 16 94 2.3E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_25755 9cdb0c84bfd292883c29d44002191919 275 Gene3D G3DSA:3.30.450.40 95 270 2.2E-50 T 14-10-2018 IPR029016 GAF-like domain superfamily LH59_25755 9cdb0c84bfd292883c29d44002191919 275 SUPERFAMILY SSF46785 24 97 2.05E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_15820 39e1d6bda174b2ec82afdffc7c363fc8 294 SUPERFAMILY SSF53850 90 292 1.74E-42 T 14-10-2018 LH59_15820 39e1d6bda174b2ec82afdffc7c363fc8 294 Gene3D G3DSA:3.40.190.10 161 263 4.5E-61 T 14-10-2018 LH59_15820 39e1d6bda174b2ec82afdffc7c363fc8 294 SUPERFAMILY SSF46785 5 86 2.07E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_15820 39e1d6bda174b2ec82afdffc7c363fc8 294 Pfam PF03466 LysR substrate binding domain 88 292 3.6E-42 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_15820 39e1d6bda174b2ec82afdffc7c363fc8 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 63 6.7E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_15820 39e1d6bda174b2ec82afdffc7c363fc8 294 Gene3D G3DSA:3.40.190.10 91 289 4.5E-61 T 14-10-2018 LH59_15820 39e1d6bda174b2ec82afdffc7c363fc8 294 Gene3D G3DSA:1.10.10.10 3 86 3.2E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_05215 2a688f68dc03a1766ee2493a728e06b2 196 Pfam PF11161 Protein of unknown function (DUF2946) 1 194 1.2E-60 T 14-10-2018 IPR021332 Protein of unknown function DUF2944 LH59_18605 2686e608f10f07fff249eef246eae8cc 247 Pfam PF01925 Sulfite exporter TauE/SafE 8 235 5.3E-27 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 LH59_26275 3277721ab5ff4c9236c9db1b32697822 271 Gene3D G3DSA:3.60.110.10 1 270 5.6E-91 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily LH59_26275 3277721ab5ff4c9236c9db1b32697822 271 SUPERFAMILY SSF56317 3 269 8.11E-79 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily LH59_26275 3277721ab5ff4c9236c9db1b32697822 271 Pfam PF00795 Carbon-nitrogen hydrolase 4 255 2.3E-57 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 LH59_14555 710a09e3ba62c1b2b979f5ecc9022718 419 SUPERFAMILY SSF103473 8 408 1.19E-58 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_14555 710a09e3ba62c1b2b979f5ecc9022718 419 Pfam PF07690 Major Facilitator Superfamily 21 297 4.4E-33 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_14555 710a09e3ba62c1b2b979f5ecc9022718 419 Gene3D G3DSA:1.20.1250.20 4 190 1.2E-47 T 14-10-2018 LH59_14555 710a09e3ba62c1b2b979f5ecc9022718 419 Gene3D G3DSA:1.20.1250.20 196 417 3.1E-49 T 14-10-2018 LH59_22980 edddebfee5792fd2843701e8337843e3 142 Pfam PF00582 Universal stress protein family 3 142 1.9E-29 T 14-10-2018 IPR006016 UspA LH59_22980 edddebfee5792fd2843701e8337843e3 142 SUPERFAMILY SSF52402 3 142 2.18E-33 T 14-10-2018 LH59_22980 edddebfee5792fd2843701e8337843e3 142 PRINTS PR01438 Universal stress protein signature 120 142 3.8E-15 T 14-10-2018 IPR006015 Universal stress protein A LH59_22980 edddebfee5792fd2843701e8337843e3 142 PRINTS PR01438 Universal stress protein signature 102 114 3.8E-15 T 14-10-2018 IPR006015 Universal stress protein A LH59_22980 edddebfee5792fd2843701e8337843e3 142 PRINTS PR01438 Universal stress protein signature 1 18 3.8E-15 T 14-10-2018 IPR006015 Universal stress protein A LH59_22980 edddebfee5792fd2843701e8337843e3 142 Gene3D G3DSA:3.40.50.620 1 142 5.9E-35 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LH59_06760 317f43c4e8b4b6023c978cccc047e8d9 306 Gene3D G3DSA:1.10.3720.10 88 299 3.0E-27 T 14-10-2018 IPR035906 MetI-like superfamily LH59_06760 317f43c4e8b4b6023c978cccc047e8d9 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 304 1.0E-45 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_06760 317f43c4e8b4b6023c978cccc047e8d9 306 SUPERFAMILY SSF161098 91 289 9.16E-23 T 14-10-2018 IPR035906 MetI-like superfamily LH59_14775 11f54323a6879eaecc8635281dcf02c8 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 158 172 1.7E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_14775 11f54323a6879eaecc8635281dcf02c8 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 188 200 1.7E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_14775 11f54323a6879eaecc8635281dcf02c8 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 188 1.7E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_14775 11f54323a6879eaecc8635281dcf02c8 218 Gene3D G3DSA:3.40.50.12740 8 217 2.2E-61 T 14-10-2018 LH59_14775 11f54323a6879eaecc8635281dcf02c8 218 SUPERFAMILY SSF46894 146 215 1.19E-21 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LH59_14775 11f54323a6879eaecc8635281dcf02c8 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 157 212 6.6E-19 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_14775 11f54323a6879eaecc8635281dcf02c8 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 172 199 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_14775 11f54323a6879eaecc8635281dcf02c8 218 Pfam PF00072 Response regulator receiver domain 11 130 3.8E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_14775 11f54323a6879eaecc8635281dcf02c8 218 SUPERFAMILY SSF52172 5 141 2.56E-32 T 14-10-2018 IPR011006 CheY-like superfamily LH59_14775 11f54323a6879eaecc8635281dcf02c8 218 SMART SM00448 8 130 8.1E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_14775 11f54323a6879eaecc8635281dcf02c8 218 SMART SM00421 155 212 6.3E-21 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_05585 85c7bfb6bec1601f0ffd38e24c111486 258 Gene3D G3DSA:3.40.50.300 1 251 1.7E-68 T 14-10-2018 LH59_05585 85c7bfb6bec1601f0ffd38e24c111486 258 SUPERFAMILY SSF52540 2 230 1.55E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_05585 85c7bfb6bec1601f0ffd38e24c111486 258 SMART SM00382 26 213 3.8E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_05585 85c7bfb6bec1601f0ffd38e24c111486 258 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_05585 85c7bfb6bec1601f0ffd38e24c111486 258 Pfam PF00005 ABC transporter 17 164 5.6E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_05285 c566e628f07496dea651bcb2b29b2cbf 299 Hamap MF_00361 NAD kinase [nadK]. 4 288 32.46 T 14-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 LH59_05285 c566e628f07496dea651bcb2b29b2cbf 299 Pfam PF01513 ATP-NAD kinase 52 272 2.0E-56 T 14-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 LH59_05285 c566e628f07496dea651bcb2b29b2cbf 299 SUPERFAMILY SSF111331 5 290 6.67E-88 T 14-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily LH59_05285 c566e628f07496dea651bcb2b29b2cbf 299 Gene3D G3DSA:3.40.50.10330 23 288 5.5E-89 T 14-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 LH59_05285 c566e628f07496dea651bcb2b29b2cbf 299 Gene3D G3DSA:2.60.200.30 126 265 5.5E-89 T 14-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 LH59_21970 84df63dd7ba24cc39e84d0ff227221d8 361 Gene3D G3DSA:2.40.50.940 224 358 6.2E-12 T 14-10-2018 LH59_21970 84df63dd7ba24cc39e84d0ff227221d8 361 SUPERFAMILY SSF52540 6 245 5.32E-88 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_21970 84df63dd7ba24cc39e84d0ff227221d8 361 SUPERFAMILY SSF50331 239 359 5.44E-13 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal LH59_21970 84df63dd7ba24cc39e84d0ff227221d8 361 Gene3D G3DSA:2.40.50.140 287 351 6.2E-12 T 14-10-2018 LH59_21970 84df63dd7ba24cc39e84d0ff227221d8 361 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_21970 84df63dd7ba24cc39e84d0ff227221d8 361 SMART SM00382 30 213 1.6E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_21970 84df63dd7ba24cc39e84d0ff227221d8 361 Gene3D G3DSA:3.40.50.300 5 223 2.9E-70 T 14-10-2018 LH59_21970 84df63dd7ba24cc39e84d0ff227221d8 361 Pfam PF00005 ABC transporter 21 163 1.5E-36 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_21970 84df63dd7ba24cc39e84d0ff227221d8 361 Pfam PF08402 TOBE domain 281 359 1.3E-9 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 LH59_22730 e63ed8f495afb390c885d53d259c9047 378 Gene3D G3DSA:3.20.20.105 1 375 1.1E-164 T 14-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 LH59_22730 e63ed8f495afb390c885d53d259c9047 378 SUPERFAMILY SSF51713 3 371 1.96E-157 T 14-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 LH59_22730 e63ed8f495afb390c885d53d259c9047 378 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 6 371 1.5E-159 T 14-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 LH59_22730 e63ed8f495afb390c885d53d259c9047 378 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 6 371 3.1E-166 T 14-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 LH59_22730 e63ed8f495afb390c885d53d259c9047 378 Pfam PF01702 Queuine tRNA-ribosyltransferase 129 369 6.3E-91 T 14-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 LH59_22730 e63ed8f495afb390c885d53d259c9047 378 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 4 372 55.264 T 14-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 LH59_06455 e1345ccf9b5d5f6530386b50ed35d413 323 Hamap MF_01206 Protein-methionine-sulfoxide reductase catalytic subunit MsrP [msrP]. 7 323 54.549 T 14-10-2018 IPR022867 Protein-methionine-sulfoxide reductase subunit MsrP GO:0016667|GO:0030091|GO:0043546|GO:0055114 LH59_06455 e1345ccf9b5d5f6530386b50ed35d413 323 SUPERFAMILY SSF56524 70 319 3.92E-89 T 14-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 LH59_06455 e1345ccf9b5d5f6530386b50ed35d413 323 Pfam PF00174 Oxidoreductase molybdopterin binding domain 102 257 2.8E-28 T 14-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 LH59_06455 e1345ccf9b5d5f6530386b50ed35d413 323 Gene3D G3DSA:3.90.420.10 60 323 1.8E-104 T 14-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 LH59_22630 4c0afed530b130f1074300a10479d05b 386 SUPERFAMILY SSF53383 22 384 9.01E-103 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_22630 4c0afed530b130f1074300a10479d05b 386 Gene3D G3DSA:3.40.640.10 5 386 8.6E-123 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_22630 4c0afed530b130f1074300a10479d05b 386 Pfam PF00155 Aminotransferase class I and II 32 377 2.1E-57 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LH59_09840 3d39762f1e9fab91fa3d32779723f970 261 Gene3D G3DSA:3.40.50.300 13 242 1.3E-62 T 14-10-2018 LH59_09840 3d39762f1e9fab91fa3d32779723f970 261 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_09840 3d39762f1e9fab91fa3d32779723f970 261 Pfam PF00005 ABC transporter 34 172 3.1E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_09840 3d39762f1e9fab91fa3d32779723f970 261 SMART SM00382 43 223 3.0E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_09840 3d39762f1e9fab91fa3d32779723f970 261 SUPERFAMILY SSF52540 16 240 4.13E-67 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_19455 d18e1ebf9aedd1424cad8286c61daafa 442 SUPERFAMILY SSF53383 37 441 5.04E-108 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_19455 d18e1ebf9aedd1424cad8286c61daafa 442 Pfam PF00202 Aminotransferase class-III 45 438 1.2E-77 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LH59_19455 d18e1ebf9aedd1424cad8286c61daafa 442 PIRSF PIRSF000521 36 144 1.2E-7 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LH59_19455 d18e1ebf9aedd1424cad8286c61daafa 442 PIRSF PIRSF000521 199 442 1.9E-30 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LH59_19455 d18e1ebf9aedd1424cad8286c61daafa 442 Gene3D G3DSA:3.40.640.10 78 337 7.0E-139 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_19455 d18e1ebf9aedd1424cad8286c61daafa 442 Gene3D G3DSA:3.90.1150.10 45 433 7.0E-139 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_19455 d18e1ebf9aedd1424cad8286c61daafa 442 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 252 290 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LH59_05035 ab84fdccd7a632722e7945f8102b9ce9 79 SUPERFAMILY SSF46689 9 77 1.36E-19 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_05035 ab84fdccd7a632722e7945f8102b9ce9 79 Pfam PF02954 Bacterial regulatory protein, Fis family 38 72 1.7E-15 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 LH59_05035 ab84fdccd7a632722e7945f8102b9ce9 79 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 41 58 1.3E-11 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 LH59_05035 ab84fdccd7a632722e7945f8102b9ce9 79 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 58 78 1.3E-11 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 LH59_05035 ab84fdccd7a632722e7945f8102b9ce9 79 PIRSF PIRSF002097 1 78 1.3E-26 T 14-10-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 LH59_05035 ab84fdccd7a632722e7945f8102b9ce9 79 Gene3D G3DSA:1.10.10.60 1 77 3.0E-22 T 14-10-2018 LH59_23355 a0a1fc22508ef634d371021227620cf5 205 Pfam PF04891 NifQ 39 200 6.4E-39 T 14-10-2018 IPR006975 NifQ GO:0009399|GO:0030151 LH59_15305 ca7a61cdcd88eddf4f26832bef05d78b 272 Pfam PF02596 Uncharacterised ArCR, COG2043 27 235 7.7E-37 T 14-10-2018 IPR003748 Protein of unknown function DUF169 LH59_19490 62f2a8c9502c0b19be75a39f28290e48 333 Gene3D G3DSA:1.10.3470.10 1 330 2.1E-98 T 14-10-2018 IPR037294 ABC transporter, BtuC-like LH59_19490 62f2a8c9502c0b19be75a39f28290e48 333 SUPERFAMILY SSF81345 9 324 2.35E-72 T 14-10-2018 IPR037294 ABC transporter, BtuC-like LH59_19490 62f2a8c9502c0b19be75a39f28290e48 333 Pfam PF01032 FecCD transport family 8 324 3.4E-86 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 LH59_06540 582700d91d2b24c5b4623e3a5bfe969a 496 Pfam PF13365 Trypsin-like peptidase domain 123 254 5.0E-34 T 14-10-2018 LH59_06540 582700d91d2b24c5b4623e3a5bfe969a 496 SMART SM00228 407 485 2.5E-4 T 14-10-2018 IPR001478 PDZ domain GO:0005515 LH59_06540 582700d91d2b24c5b4623e3a5bfe969a 496 SMART SM00228 293 375 4.5E-10 T 14-10-2018 IPR001478 PDZ domain GO:0005515 LH59_06540 582700d91d2b24c5b4623e3a5bfe969a 496 SUPERFAMILY SSF50494 48 284 7.73E-67 T 14-10-2018 IPR009003 Peptidase S1, PA clan LH59_06540 582700d91d2b24c5b4623e3a5bfe969a 496 SUPERFAMILY SSF50156 276 383 2.89E-21 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 LH59_06540 582700d91d2b24c5b4623e3a5bfe969a 496 Gene3D G3DSA:2.30.42.10 405 496 1.3E-13 T 14-10-2018 LH59_06540 582700d91d2b24c5b4623e3a5bfe969a 496 Gene3D G3DSA:2.30.42.10 288 392 1.5E-26 T 14-10-2018 LH59_06540 582700d91d2b24c5b4623e3a5bfe969a 496 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 50 490 6.8E-144 T 14-10-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 LH59_06540 582700d91d2b24c5b4623e3a5bfe969a 496 Gene3D G3DSA:2.40.10.120 48 286 1.2E-80 T 14-10-2018 LH59_06540 582700d91d2b24c5b4623e3a5bfe969a 496 SUPERFAMILY SSF50156 408 492 6.97E-13 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 LH59_06540 582700d91d2b24c5b4623e3a5bfe969a 496 Pfam PF13180 PDZ domain 418 492 6.6E-9 T 14-10-2018 IPR001478 PDZ domain GO:0005515 LH59_06540 582700d91d2b24c5b4623e3a5bfe969a 496 Pfam PF13180 PDZ domain 296 384 2.0E-14 T 14-10-2018 IPR001478 PDZ domain GO:0005515 LH59_06540 582700d91d2b24c5b4623e3a5bfe969a 496 PRINTS PR00834 HtrA/DegQ protease family signature 153 173 1.0E-52 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 LH59_06540 582700d91d2b24c5b4623e3a5bfe969a 496 PRINTS PR00834 HtrA/DegQ protease family signature 247 264 1.0E-52 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 LH59_06540 582700d91d2b24c5b4623e3a5bfe969a 496 PRINTS PR00834 HtrA/DegQ protease family signature 193 217 1.0E-52 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 LH59_06540 582700d91d2b24c5b4623e3a5bfe969a 496 PRINTS PR00834 HtrA/DegQ protease family signature 333 345 1.0E-52 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 LH59_06540 582700d91d2b24c5b4623e3a5bfe969a 496 PRINTS PR00834 HtrA/DegQ protease family signature 225 242 1.0E-52 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 LH59_06540 582700d91d2b24c5b4623e3a5bfe969a 496 PRINTS PR00834 HtrA/DegQ protease family signature 132 144 1.0E-52 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 LH59_11500 858a3d5d765ad2e29ae12dcd83439e75 203 Pfam PF03748 Flagellar basal body-associated protein FliL 103 203 1.9E-21 T 14-10-2018 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 LH59_06755 22fb65710662010212eaf39fffc121c0 517 Gene3D G3DSA:3.40.190.10 188 500 1.2E-161 T 14-10-2018 LH59_06755 22fb65710662010212eaf39fffc121c0 517 SUPERFAMILY SSF53850 33 514 6.42E-140 T 14-10-2018 LH59_06755 22fb65710662010212eaf39fffc121c0 517 Gene3D G3DSA:3.90.76.10 41 187 1.2E-161 T 14-10-2018 LH59_06755 22fb65710662010212eaf39fffc121c0 517 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 72 431 2.2E-96 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain LH59_06755 22fb65710662010212eaf39fffc121c0 517 PIRSF PIRSF002741 4 513 1.4E-111 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 LH59_06755 22fb65710662010212eaf39fffc121c0 517 Gene3D G3DSA:3.10.105.10 263 490 1.2E-161 T 14-10-2018 LH59_06755 22fb65710662010212eaf39fffc121c0 517 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 78 100 - T 14-10-2018 IPR023765 Solute-binding protein family 5, conserved site LH59_16970 86cfb124d62e875909ae891157785b4d 152 Gene3D G3DSA:3.10.180.10 9 133 4.7E-19 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_16970 86cfb124d62e875909ae891157785b4d 152 SUPERFAMILY SSF54593 5 134 2.89E-18 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_16970 86cfb124d62e875909ae891157785b4d 152 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 129 3.3E-7 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain LH59_21770 816502c9a51f41210461fc8f7469b52c 181 Gene3D G3DSA:2.30.180.10 34 181 2.5E-44 T 14-10-2018 IPR036378 FAS1 domain superfamily LH59_21770 816502c9a51f41210461fc8f7469b52c 181 Pfam PF02469 Fasciclin domain 46 180 2.8E-32 T 14-10-2018 IPR000782 FAS1 domain LH59_21770 816502c9a51f41210461fc8f7469b52c 181 SUPERFAMILY SSF82153 36 180 1.01E-37 T 14-10-2018 IPR036378 FAS1 domain superfamily LH59_21770 816502c9a51f41210461fc8f7469b52c 181 SMART SM00554 70 181 1.7E-25 T 14-10-2018 IPR000782 FAS1 domain LH59_25150 a39bacc45b61fe647ddb57120f0960be 872 Pfam PF00330 Aconitase family (aconitate hydratase) 70 533 3.9E-149 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 LH59_25150 a39bacc45b61fe647ddb57120f0960be 872 Gene3D G3DSA:3.30.499.10 361 561 8.5E-75 T 14-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 LH59_25150 a39bacc45b61fe647ddb57120f0960be 872 TIGRFAM TIGR02333 2met_isocit_dHY: 2-methylisocitrate dehydratase, Fe/S-dependent 2 860 0.0 T 14-10-2018 IPR012708 2-methylisocitrate dehydratase AcnD, Fe/S-dependent GO:0019679 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3 LH59_25150 a39bacc45b61fe647ddb57120f0960be 872 Gene3D G3DSA:3.30.499.20 6 360 4.5E-133 T 14-10-2018 LH59_25150 a39bacc45b61fe647ddb57120f0960be 872 Gene3D G3DSA:1.10.1440.20 562 619 3.7E-9 T 14-10-2018 LH59_25150 a39bacc45b61fe647ddb57120f0960be 872 PRINTS PR00415 Aconitase family signature 162 170 4.0E-30 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 LH59_25150 a39bacc45b61fe647ddb57120f0960be 872 PRINTS PR00415 Aconitase family signature 191 204 4.0E-30 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 LH59_25150 a39bacc45b61fe647ddb57120f0960be 872 PRINTS PR00415 Aconitase family signature 402 413 4.0E-30 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 LH59_25150 a39bacc45b61fe647ddb57120f0960be 872 PRINTS PR00415 Aconitase family signature 267 280 4.0E-30 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 LH59_25150 a39bacc45b61fe647ddb57120f0960be 872 PRINTS PR00415 Aconitase family signature 360 374 4.0E-30 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 LH59_25150 a39bacc45b61fe647ddb57120f0960be 872 PRINTS PR00415 Aconitase family signature 464 477 4.0E-30 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 LH59_25150 a39bacc45b61fe647ddb57120f0960be 872 PRINTS PR00415 Aconitase family signature 138 151 4.0E-30 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 LH59_25150 a39bacc45b61fe647ddb57120f0960be 872 PRINTS PR00415 Aconitase family signature 205 220 4.0E-30 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 LH59_25150 a39bacc45b61fe647ddb57120f0960be 872 PRINTS PR00415 Aconitase family signature 281 294 4.0E-30 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 LH59_25150 a39bacc45b61fe647ddb57120f0960be 872 SUPERFAMILY SSF52016 599 858 8.63E-68 T 14-10-2018 LH59_25150 a39bacc45b61fe647ddb57120f0960be 872 SUPERFAMILY SSF53732 22 587 1.44E-188 T 14-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 LH59_25150 a39bacc45b61fe647ddb57120f0960be 872 Pfam PF00694 Aconitase C-terminal domain 657 788 2.3E-29 T 14-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 LH59_25150 a39bacc45b61fe647ddb57120f0960be 872 Gene3D G3DSA:3.20.19.10 620 859 1.4E-83 T 14-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 LH59_26655 f4d6ade8e9e75a9ff4ba5fc1051926b3 477 Gene3D G3DSA:1.10.10.10 1 67 3.1E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_26655 f4d6ade8e9e75a9ff4ba5fc1051926b3 477 Gene3D G3DSA:3.90.1150.10 97 465 4.3E-106 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_26655 f4d6ade8e9e75a9ff4ba5fc1051926b3 477 SUPERFAMILY SSF53383 96 466 1.71E-97 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_26655 f4d6ade8e9e75a9ff4ba5fc1051926b3 477 Gene3D G3DSA:3.40.640.10 142 360 4.3E-106 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_26655 f4d6ade8e9e75a9ff4ba5fc1051926b3 477 Pfam PF00392 Bacterial regulatory proteins, gntR family 3 66 2.7E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_26655 f4d6ade8e9e75a9ff4ba5fc1051926b3 477 SMART SM00345 7 66 1.7E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_26655 f4d6ade8e9e75a9ff4ba5fc1051926b3 477 SUPERFAMILY SSF46785 2 70 1.95E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_26655 f4d6ade8e9e75a9ff4ba5fc1051926b3 477 Pfam PF00155 Aminotransferase class I and II 148 449 2.7E-35 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LH59_19030 e6050150f178a76fdcad0d1bc4b2851a 318 Pfam PF10094 Uncharacterized protein conserved in bacteria (DUF2332) 68 317 3.3E-66 T 14-10-2018 IPR011200 Uncharacterised conserved protein UCP012608 LH59_19030 e6050150f178a76fdcad0d1bc4b2851a 318 Pfam PF10094 Uncharacterized protein conserved in bacteria (DUF2332) 6 60 1.1E-8 T 14-10-2018 IPR011200 Uncharacterised conserved protein UCP012608 LH59_07535 8feb397c1610281f91beb642302fac43 88 PRINTS PR01249 Ribosomal protein L31 signature 44 59 5.2E-14 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_07535 8feb397c1610281f91beb642302fac43 88 PRINTS PR01249 Ribosomal protein L31 signature 2 19 5.2E-14 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_07535 8feb397c1610281f91beb642302fac43 88 PRINTS PR01249 Ribosomal protein L31 signature 59 77 5.2E-14 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_07535 8feb397c1610281f91beb642302fac43 88 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 80 23.402 T 14-10-2018 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_07535 8feb397c1610281f91beb642302fac43 88 Pfam PF01197 Ribosomal protein L31 1 78 1.3E-27 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_07535 8feb397c1610281f91beb642302fac43 88 ProSitePatterns PS01143 Ribosomal protein L31 signature. 48 69 - T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_07535 8feb397c1610281f91beb642302fac43 88 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 78 6.1E-19 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_07535 8feb397c1610281f91beb642302fac43 88 SUPERFAMILY SSF143800 1 78 5.1E-20 T 14-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_07535 8feb397c1610281f91beb642302fac43 88 Gene3D G3DSA:2.30.170.50 1 82 6.7E-24 T 14-10-2018 LH59_27035 ee632b5e8f2ef6313f7e908d4a3bb0b0 267 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 5 78 7.9E-21 T 14-10-2018 IPR013589 Bacterial transglutaminase-like, N-terminal LH59_27035 ee632b5e8f2ef6313f7e908d4a3bb0b0 267 SMART SM00460 158 220 8.7E-16 T 14-10-2018 IPR002931 Transglutaminase-like LH59_27035 ee632b5e8f2ef6313f7e908d4a3bb0b0 267 Gene3D G3DSA:3.10.620.30 88 254 1.2E-45 T 14-10-2018 LH59_27035 ee632b5e8f2ef6313f7e908d4a3bb0b0 267 Pfam PF01841 Transglutaminase-like superfamily 129 217 4.1E-23 T 14-10-2018 IPR002931 Transglutaminase-like LH59_27035 ee632b5e8f2ef6313f7e908d4a3bb0b0 267 SUPERFAMILY SSF54001 7 246 3.73E-39 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily LH59_24395 551c9b705d275f3e89f87ace2edcc4cf 321 SUPERFAMILY SSF56042 141 304 5.83E-31 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily LH59_24395 551c9b705d275f3e89f87ace2edcc4cf 321 Gene3D G3DSA:3.90.650.10 144 318 3.0E-46 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily LH59_24395 551c9b705d275f3e89f87ace2edcc4cf 321 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 4 318 7.0E-92 T 14-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 LH59_24395 551c9b705d275f3e89f87ace2edcc4cf 321 Gene3D G3DSA:3.30.1330.10 1 142 1.4E-48 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily LH59_24395 551c9b705d275f3e89f87ace2edcc4cf 321 Pfam PF00586 AIR synthase related protein, N-terminal domain 25 136 9.9E-26 T 14-10-2018 IPR016188 PurM-like, N-terminal domain LH59_24395 551c9b705d275f3e89f87ace2edcc4cf 321 Pfam PF02769 AIR synthase related protein, C-terminal domain 188 300 3.4E-10 T 14-10-2018 IPR010918 PurM-like, C-terminal domain LH59_24395 551c9b705d275f3e89f87ace2edcc4cf 321 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 2 318 25.608 T 14-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 LH59_24395 551c9b705d275f3e89f87ace2edcc4cf 321 PIRSF PIRSF005303 2 318 4.3E-74 T 14-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 LH59_24395 551c9b705d275f3e89f87ace2edcc4cf 321 SUPERFAMILY SSF55326 4 136 3.89E-35 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily LH59_21050 0f97f6230bc125f63f89b90ffc8b700b 311 Pfam PF00701 Dihydrodipicolinate synthetase family 12 292 3.4E-26 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_21050 0f97f6230bc125f63f89b90ffc8b700b 311 PIRSF PIRSF001365 8 309 3.3E-46 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_21050 0f97f6230bc125f63f89b90ffc8b700b 311 SMART SM01130 10 303 2.0E-54 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_21050 0f97f6230bc125f63f89b90ffc8b700b 311 Gene3D G3DSA:3.20.20.70 4 311 3.1E-105 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_21050 0f97f6230bc125f63f89b90ffc8b700b 311 SUPERFAMILY SSF51569 7 305 2.62E-63 T 14-10-2018 LH59_20135 f13e811e80f3d9bb4260242c5e09cee7 284 Gene3D G3DSA:3.30.30.40 123 159 1.3E-55 T 14-10-2018 LH59_20135 f13e811e80f3d9bb4260242c5e09cee7 284 Pfam PF01144 Coenzyme A transferase 13 227 1.3E-20 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 LH59_20135 f13e811e80f3d9bb4260242c5e09cee7 284 SUPERFAMILY SSF100950 10 257 1.44E-59 T 14-10-2018 IPR037171 NagB/RpiA transferase-like LH59_20135 f13e811e80f3d9bb4260242c5e09cee7 284 SMART SM00882 11 231 1.7E-30 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 LH59_20135 f13e811e80f3d9bb4260242c5e09cee7 284 Gene3D G3DSA:3.40.1080.10 18 257 1.3E-55 T 14-10-2018 LH59_24425 c9d54ff4f36441a0f73501932a226e2f 332 Gene3D G3DSA:3.40.190.10 147 254 2.1E-54 T 14-10-2018 LH59_24425 c9d54ff4f36441a0f73501932a226e2f 332 SUPERFAMILY SSF53850 73 312 4.81E-50 T 14-10-2018 LH59_24425 c9d54ff4f36441a0f73501932a226e2f 332 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 64 299 1.8E-55 T 14-10-2018 LH59_24425 c9d54ff4f36441a0f73501932a226e2f 332 TIGRFAM TIGR01098 3A0109s03R: phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein 7 279 1.1E-64 T 14-10-2018 IPR005770 Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein GO:0043190|GO:0055085 LH59_24425 c9d54ff4f36441a0f73501932a226e2f 332 Gene3D G3DSA:3.40.190.10 65 280 2.1E-54 T 14-10-2018 LH59_08395 844b08f802c4e504e9253b84e747022c 302 SUPERFAMILY SSF103481 195 291 2.22E-7 T 14-10-2018 LH59_08395 844b08f802c4e504e9253b84e747022c 302 Pfam PF00892 EamA-like transporter family 11 141 1.9E-8 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_08395 844b08f802c4e504e9253b84e747022c 302 Pfam PF00892 EamA-like transporter family 165 289 2.1E-6 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_08395 844b08f802c4e504e9253b84e747022c 302 SUPERFAMILY SSF103481 51 144 4.71E-6 T 14-10-2018 LH59_02575 41df75426788cfa2915c8d9a4a5b8664 219 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 110 2.1E-25 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 LH59_02575 41df75426788cfa2915c8d9a4a5b8664 219 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 202 4.7E-20 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_02575 41df75426788cfa2915c8d9a4a5b8664 219 Gene3D G3DSA:1.10.3720.10 1 216 4.7E-50 T 14-10-2018 IPR035906 MetI-like superfamily LH59_02575 41df75426788cfa2915c8d9a4a5b8664 219 SUPERFAMILY SSF161098 13 213 1.83E-42 T 14-10-2018 IPR035906 MetI-like superfamily LH59_01665 9cb800bdeb137a22fc0581101e6463ce 277 PIRSF PIRSF002854 1 268 2.8E-74 T 14-10-2018 IPR004872 Lipoprotein NlpA family LH59_01665 9cb800bdeb137a22fc0581101e6463ce 277 SUPERFAMILY SSF53850 33 267 1.69E-63 T 14-10-2018 LH59_01665 9cb800bdeb137a22fc0581101e6463ce 277 Pfam PF03180 NLPA lipoprotein 33 265 2.9E-75 T 14-10-2018 IPR004872 Lipoprotein NlpA family LH59_01665 9cb800bdeb137a22fc0581101e6463ce 277 Gene3D G3DSA:3.40.190.10 112 220 1.1E-80 T 14-10-2018 LH59_01665 9cb800bdeb137a22fc0581101e6463ce 277 Gene3D G3DSA:3.40.190.10 49 263 1.1E-80 T 14-10-2018 LH59_18955 a9f55bdca56a9a7d1d45c805b6429faf 210 Gene3D G3DSA:3.55.50.30 8 117 1.3E-22 T 14-10-2018 LH59_18955 a9f55bdca56a9a7d1d45c805b6429faf 210 SMART SM00965 40 91 1.6E-10 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 LH59_18955 a9f55bdca56a9a7d1d45c805b6429faf 210 Pfam PF07660 Secretin and TonB N terminus short domain 42 89 8.7E-7 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 LH59_18955 a9f55bdca56a9a7d1d45c805b6429faf 210 SUPERFAMILY SSF74653 92 183 1.83E-7 T 14-10-2018 LH59_26355 50d664cd440fec0b4c6e25172deccc3c 251 Pfam PF00899 ThiF family 9 243 2.7E-66 T 14-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 LH59_26355 50d664cd440fec0b4c6e25172deccc3c 251 Gene3D G3DSA:3.40.50.720 1 250 1.5E-95 T 14-10-2018 LH59_26355 50d664cd440fec0b4c6e25172deccc3c 251 SUPERFAMILY SSF69572 2 248 1.03E-87 T 14-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 LH59_02175 7c2c66f413924f921b2787471933b1ee 382 PIRSF PIRSF016578 15 367 7.4E-19 T 14-10-2018 LH59_02175 7c2c66f413924f921b2787471933b1ee 382 Gene3D G3DSA:1.20.140.10 235 382 1.5E-55 T 14-10-2018 LH59_02175 7c2c66f413924f921b2787471933b1ee 382 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 5 117 3.7E-25 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 LH59_02175 7c2c66f413924f921b2787471933b1ee 382 SUPERFAMILY SSF47203 227 379 4.35E-56 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 LH59_02175 7c2c66f413924f921b2787471933b1ee 382 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 123 135 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 LH59_02175 7c2c66f413924f921b2787471933b1ee 382 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 216 3.0E-27 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 LH59_02175 7c2c66f413924f921b2787471933b1ee 382 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 LH59_02175 7c2c66f413924f921b2787471933b1ee 382 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 377 5.8E-49 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LH59_02175 7c2c66f413924f921b2787471933b1ee 382 SUPERFAMILY SSF56645 5 242 4.19E-73 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 LH59_02175 7c2c66f413924f921b2787471933b1ee 382 Gene3D G3DSA:1.10.540.10 2 118 2.9E-28 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 LH59_02175 7c2c66f413924f921b2787471933b1ee 382 Gene3D G3DSA:2.40.110.10 120 234 9.7E-40 T 14-10-2018 LH59_12490 6bc3fcee1222dc0af63bd557b0b10a2c 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 6.4E-20 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_12490 6bc3fcee1222dc0af63bd557b0b10a2c 302 SUPERFAMILY SSF53850 90 295 1.61E-30 T 14-10-2018 LH59_12490 6bc3fcee1222dc0af63bd557b0b10a2c 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 3.7E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_12490 6bc3fcee1222dc0af63bd557b0b10a2c 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 3.7E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_12490 6bc3fcee1222dc0af63bd557b0b10a2c 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 3.7E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_12490 6bc3fcee1222dc0af63bd557b0b10a2c 302 Gene3D G3DSA:1.10.10.10 1 90 2.5E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_12490 6bc3fcee1222dc0af63bd557b0b10a2c 302 SUPERFAMILY SSF46785 2 110 1.57E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_12490 6bc3fcee1222dc0af63bd557b0b10a2c 302 Pfam PF03466 LysR substrate binding domain 90 291 2.0E-32 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_12490 6bc3fcee1222dc0af63bd557b0b10a2c 302 Gene3D G3DSA:3.40.190.290 91 298 1.7E-25 T 14-10-2018 LH59_02135 961ad05281835896feb996500b452b79 304 Pfam PF03466 LysR substrate binding domain 89 294 1.5E-35 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_02135 961ad05281835896feb996500b452b79 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 9.2E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_02135 961ad05281835896feb996500b452b79 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 9.2E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_02135 961ad05281835896feb996500b452b79 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 9.2E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_02135 961ad05281835896feb996500b452b79 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 9.4E-19 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_02135 961ad05281835896feb996500b452b79 304 SUPERFAMILY SSF53850 90 295 1.04E-35 T 14-10-2018 LH59_02135 961ad05281835896feb996500b452b79 304 Gene3D G3DSA:1.10.10.10 4 88 9.3E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_02135 961ad05281835896feb996500b452b79 304 SUPERFAMILY SSF46785 6 111 3.98E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_02135 961ad05281835896feb996500b452b79 304 Gene3D G3DSA:3.40.190.290 90 298 5.8E-33 T 14-10-2018 LH59_04505 c1fa9ebcdb21bf0cae87bead7e344961 390 Pfam PF02803 Thiolase, C-terminal domain 265 367 1.2E-6 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 LH59_04505 c1fa9ebcdb21bf0cae87bead7e344961 390 SUPERFAMILY SSF53901 235 376 5.28E-28 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_04505 c1fa9ebcdb21bf0cae87bead7e344961 390 Gene3D G3DSA:3.40.47.10 4 386 4.5E-113 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_04505 c1fa9ebcdb21bf0cae87bead7e344961 390 SUPERFAMILY SSF53901 28 334 7.8E-25 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_04505 c1fa9ebcdb21bf0cae87bead7e344961 390 PIRSF PIRSF000429 7 384 1.0E-28 T 14-10-2018 IPR002155 Thiolase GO:0016747 LH59_02385 c0f330d89762bdba52707bb818518116 204 TIGRFAM TIGR02081 metW: methionine biosynthesis protein MetW 14 201 4.0E-89 T 14-10-2018 IPR010743 Methionine biosynthesis MetW KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 LH59_02385 c0f330d89762bdba52707bb818518116 204 Gene3D G3DSA:3.40.50.150 8 184 1.5E-25 T 14-10-2018 LH59_02385 c0f330d89762bdba52707bb818518116 204 Pfam PF07021 Methionine biosynthesis protein MetW 14 200 9.6E-77 T 14-10-2018 IPR010743 Methionine biosynthesis MetW KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 LH59_02385 c0f330d89762bdba52707bb818518116 204 SUPERFAMILY SSF53335 15 199 2.39E-31 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_16935 97fc4e6bce721f18ba97e25d451dfa8c 355 Pfam PF16220 Domain of unknown function (DUF4880) 17 58 1.9E-12 T 14-10-2018 IPR032623 FecR, N-terminal LH59_16935 97fc4e6bce721f18ba97e25d451dfa8c 355 PIRSF PIRSF018266 6 355 4.3E-83 T 14-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component LH59_16935 97fc4e6bce721f18ba97e25d451dfa8c 355 Pfam PF04773 FecR protein 145 237 1.1E-19 T 14-10-2018 IPR006860 FecR protein LH59_16935 97fc4e6bce721f18ba97e25d451dfa8c 355 Gene3D G3DSA:2.60.120.1440 137 274 2.5E-27 T 14-10-2018 LH59_26140 59b58467315fd569378c21003babdb58 424 Gene3D G3DSA:3.30.460.30 3 160 6.0E-52 T 14-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 LH59_26140 59b58467315fd569378c21003babdb58 424 SUPERFAMILY SSF69075 319 418 2.09E-27 T 14-10-2018 IPR036453 Glutamyl tRNA-reductase dimerization domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 LH59_26140 59b58467315fd569378c21003babdb58 424 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 101 124 - T 14-10-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 LH59_26140 59b58467315fd569378c21003babdb58 424 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 6 413 9.6E-129 T 14-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 LH59_26140 59b58467315fd569378c21003babdb58 424 SUPERFAMILY SSF69742 5 160 9.68E-44 T 14-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 LH59_26140 59b58467315fd569378c21003babdb58 424 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 174 306 1.5E-43 T 14-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase LH59_26140 59b58467315fd569378c21003babdb58 424 SUPERFAMILY SSF51735 165 316 6.68E-32 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_26140 59b58467315fd569378c21003babdb58 424 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 9 158 2.3E-45 T 14-10-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 LH59_26140 59b58467315fd569378c21003babdb58 424 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 322 417 2.4E-27 T 14-10-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 LH59_26140 59b58467315fd569378c21003babdb58 424 PIRSF PIRSF000445 3 424 2.9E-146 T 14-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 LH59_26140 59b58467315fd569378c21003babdb58 424 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 4 417 29.212 T 14-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 LH59_26140 59b58467315fd569378c21003babdb58 424 Gene3D G3DSA:3.40.50.720 163 314 4.2E-42 T 14-10-2018 LH59_14560 2672f3ad72a7dfe8f2630a15891bb65c 416 Pfam PF05940 NnrS protein 23 393 1.0E-89 T 14-10-2018 IPR010266 NnrS LH59_25880 c8c20e94bc44a29f3f73d8ca9158ece5 266 Gene3D G3DSA:2.60.120.10 18 98 1.5E-8 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_25880 c8c20e94bc44a29f3f73d8ca9158ece5 266 Gene3D G3DSA:1.10.10.60 161 264 3.1E-22 T 14-10-2018 LH59_25880 c8c20e94bc44a29f3f73d8ca9158ece5 266 SUPERFAMILY SSF46689 214 260 9.86E-8 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_25880 c8c20e94bc44a29f3f73d8ca9158ece5 266 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 228 243 5.4E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 LH59_25880 c8c20e94bc44a29f3f73d8ca9158ece5 266 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 243 259 5.4E-5 T 14-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 LH59_25880 c8c20e94bc44a29f3f73d8ca9158ece5 266 SMART SM00342 177 259 4.5E-22 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_25880 c8c20e94bc44a29f3f73d8ca9158ece5 266 SUPERFAMILY SSF51182 12 206 5.69E-21 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_25880 c8c20e94bc44a29f3f73d8ca9158ece5 266 Pfam PF12833 Helix-turn-helix domain 183 261 9.0E-24 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_25880 c8c20e94bc44a29f3f73d8ca9158ece5 266 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 214 255 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 LH59_03425 eae52edfed25d5d72aba42c192ddaabb 319 Gene3D G3DSA:3.40.50.880 2 203 1.7E-46 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_03425 eae52edfed25d5d72aba42c192ddaabb 319 SUPERFAMILY SSF46689 216 266 5.02E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_03425 eae52edfed25d5d72aba42c192ddaabb 319 SMART SM00342 232 315 8.3E-21 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_03425 eae52edfed25d5d72aba42c192ddaabb 319 SUPERFAMILY SSF52317 1 197 7.25E-33 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_03425 eae52edfed25d5d72aba42c192ddaabb 319 Gene3D G3DSA:1.10.10.60 215 318 2.3E-23 T 14-10-2018 LH59_03425 eae52edfed25d5d72aba42c192ddaabb 319 Pfam PF01965 DJ-1/PfpI family 67 175 4.4E-10 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 LH59_03425 eae52edfed25d5d72aba42c192ddaabb 319 Pfam PF12833 Helix-turn-helix domain 238 315 8.4E-19 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_03425 eae52edfed25d5d72aba42c192ddaabb 319 SUPERFAMILY SSF46689 268 316 4.48E-7 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_10835 5acd73efbbddc1ce6cea886a91198066 397 SUPERFAMILY SSF103473 10 389 4.32E-49 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_10835 5acd73efbbddc1ce6cea886a91198066 397 Gene3D G3DSA:1.20.1250.20 19 391 8.7E-39 T 14-10-2018 LH59_10835 5acd73efbbddc1ce6cea886a91198066 397 Pfam PF07690 Major Facilitator Superfamily 30 360 8.5E-29 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_06970 b584f6de006e9c9a0544ec6370bde687 955 Gene3D G3DSA:3.40.50.11610 735 942 1.3E-167 T 14-10-2018 LH59_06970 b584f6de006e9c9a0544ec6370bde687 955 Pfam PF00676 Dehydrogenase E1 component 221 525 1.9E-49 T 14-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 LH59_06970 b584f6de006e9c9a0544ec6370bde687 955 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 10 48 1.0E-17 T 14-10-2018 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 LH59_06970 b584f6de006e9c9a0544ec6370bde687 955 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 13 944 0.0 T 14-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 LH59_06970 b584f6de006e9c9a0544ec6370bde687 955 Gene3D G3DSA:3.40.50.970 173 534 5.9E-148 T 14-10-2018 LH59_06970 b584f6de006e9c9a0544ec6370bde687 955 SMART SM00861 601 798 5.7E-57 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain LH59_06970 b584f6de006e9c9a0544ec6370bde687 955 SUPERFAMILY SSF52518 126 551 5.17E-89 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold LH59_06970 b584f6de006e9c9a0544ec6370bde687 955 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 803 945 6.8E-50 T 14-10-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 LH59_06970 b584f6de006e9c9a0544ec6370bde687 955 SUPERFAMILY SSF52518 585 804 1.18E-45 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold LH59_06970 b584f6de006e9c9a0544ec6370bde687 955 Pfam PF02779 Transketolase, pyrimidine binding domain 601 798 1.3E-63 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain LH59_06970 b584f6de006e9c9a0544ec6370bde687 955 Gene3D G3DSA:3.40.50.12470 564 814 1.3E-167 T 14-10-2018 LH59_06970 b584f6de006e9c9a0544ec6370bde687 955 PIRSF PIRSF000157 1 947 0.0 T 14-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 LH59_06970 b584f6de006e9c9a0544ec6370bde687 955 Gene3D G3DSA:1.10.287.1150 89 172 7.3E-24 T 14-10-2018 LH59_22665 96bb618ca2069f562de9bafdda711c4c 105 Pfam PF05957 Bacterial protein of unknown function (DUF883) 13 105 9.8E-31 T 14-10-2018 IPR010279 Inner membrane protein YqjD/ElaB GO:0043022 LH59_02305 11d9ea9de13e23b9a5d15291b15b07b5 330 SUPERFAMILY SSF53850 110 290 1.81E-7 T 14-10-2018 LH59_02305 11d9ea9de13e23b9a5d15291b15b07b5 330 Gene3D G3DSA:3.40.190.150 33 311 2.2E-89 T 14-10-2018 LH59_02305 11d9ea9de13e23b9a5d15291b15b07b5 330 Gene3D G3DSA:3.40.190.10 131 256 2.2E-89 T 14-10-2018 LH59_02305 11d9ea9de13e23b9a5d15291b15b07b5 330 PIRSF PIRSF017082 2 326 2.5E-62 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_02305 11d9ea9de13e23b9a5d15291b15b07b5 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 324 9.1E-60 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_05510 1289dca6c829695e1a95d42f46cf3be3 313 Gene3D G3DSA:1.10.3720.10 85 305 1.0E-26 T 14-10-2018 IPR035906 MetI-like superfamily LH59_05510 1289dca6c829695e1a95d42f46cf3be3 313 SUPERFAMILY SSF161098 97 298 1.16E-20 T 14-10-2018 IPR035906 MetI-like superfamily LH59_05510 1289dca6c829695e1a95d42f46cf3be3 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 313 5.5E-46 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_10320 ecd27f14d2c27ff834b7d6a1319dc182 329 PIRSF PIRSF017082 1 329 2.5E-97 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_10320 ecd27f14d2c27ff834b7d6a1319dc182 329 SUPERFAMILY SSF53850 106 292 5.69E-11 T 14-10-2018 LH59_10320 ecd27f14d2c27ff834b7d6a1319dc182 329 Gene3D G3DSA:3.40.190.10 131 254 1.0E-85 T 14-10-2018 LH59_10320 ecd27f14d2c27ff834b7d6a1319dc182 329 Gene3D G3DSA:3.40.190.150 33 318 1.0E-85 T 14-10-2018 LH59_10320 ecd27f14d2c27ff834b7d6a1319dc182 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 312 7.9E-50 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_10730 7e66d4ef5ff390a2e49fe6dc48df8a41 234 SUPERFAMILY SSF52317 2 181 4.74E-51 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_10730 7e66d4ef5ff390a2e49fe6dc48df8a41 234 Pfam PF01965 DJ-1/PfpI family 3 162 9.6E-29 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 LH59_10730 7e66d4ef5ff390a2e49fe6dc48df8a41 234 Gene3D G3DSA:3.40.50.880 1 229 9.0E-73 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_22790 9610d140740c7011ec5f6930fc4d23d9 296 Pfam PF03471 Transporter associated domain 210 284 1.8E-17 T 14-10-2018 IPR005170 Transporter-associated domain LH59_22790 9610d140740c7011ec5f6930fc4d23d9 296 SMART SM01091 207 285 1.5E-24 T 14-10-2018 IPR005170 Transporter-associated domain LH59_22790 9610d140740c7011ec5f6930fc4d23d9 296 SUPERFAMILY SSF54631 70 204 4.17E-29 T 14-10-2018 LH59_22790 9610d140740c7011ec5f6930fc4d23d9 296 SUPERFAMILY SSF56176 205 286 7.63E-20 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 LH59_22790 9610d140740c7011ec5f6930fc4d23d9 296 Pfam PF00571 CBS domain 142 191 4.7E-4 T 14-10-2018 IPR000644 CBS domain LH59_22790 9610d140740c7011ec5f6930fc4d23d9 296 Pfam PF00571 CBS domain 85 131 7.7E-4 T 14-10-2018 IPR000644 CBS domain LH59_22790 9610d140740c7011ec5f6930fc4d23d9 296 Gene3D G3DSA:3.10.580.10 53 197 5.3E-51 T 14-10-2018 LH59_22790 9610d140740c7011ec5f6930fc4d23d9 296 Gene3D G3DSA:3.30.465.10 198 285 5.1E-24 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 LH59_13800 2e5187c95af9b1adb11689a3cac8eb13 360 PIRSF PIRSF005508 3 359 1.2E-118 T 14-10-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 LH59_13800 2e5187c95af9b1adb11689a3cac8eb13 360 Pfam PF01758 Sodium Bile acid symporter family 64 257 1.8E-36 T 14-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 LH59_13800 2e5187c95af9b1adb11689a3cac8eb13 360 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 18 345 8.1E-118 T 14-10-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 LH59_13800 2e5187c95af9b1adb11689a3cac8eb13 360 Gene3D G3DSA:1.20.1530.20 15 347 1.8E-18 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily LH59_16905 5b8211a6c83b679a57d7b54b5228c11c 547 SUPERFAMILY SSF53649 40 483 3.93E-119 T 14-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 LH59_16905 5b8211a6c83b679a57d7b54b5228c11c 547 Gene3D G3DSA:3.40.720.10 43 415 1.3E-96 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 LH59_16905 5b8211a6c83b679a57d7b54b5228c11c 547 Gene3D G3DSA:3.30.1120.10 416 486 1.3E-96 T 14-10-2018 LH59_16905 5b8211a6c83b679a57d7b54b5228c11c 547 Pfam PF00884 Sulfatase 43 372 2.2E-62 T 14-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 LH59_22005 5b3c1bdd10f3593b0718b3bdff7e1176 317 Hamap MF_00492 Transaldolase [tal]. 2 316 47.503 T 14-10-2018 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 LH59_22005 5b3c1bdd10f3593b0718b3bdff7e1176 317 SUPERFAMILY SSF51569 1 314 1.15E-102 T 14-10-2018 LH59_22005 5b3c1bdd10f3593b0718b3bdff7e1176 317 ProSitePatterns PS00958 Transaldolase active site. 123 140 - T 14-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 LH59_22005 5b3c1bdd10f3593b0718b3bdff7e1176 317 ProSitePatterns PS01054 Transaldolase signature 1. 31 39 - T 14-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 LH59_22005 5b3c1bdd10f3593b0718b3bdff7e1176 317 Gene3D G3DSA:3.20.20.70 1 317 1.0E-125 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_22005 5b3c1bdd10f3593b0718b3bdff7e1176 317 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 14 310 5.2E-93 T 14-10-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 LH59_22005 5b3c1bdd10f3593b0718b3bdff7e1176 317 TIGRFAM TIGR00874 talAB: transaldolase 3 314 5.9E-127 T 14-10-2018 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 LH59_11165 8fbb50ef5e95e26ce26e7dc968d43330 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 9.3E-13 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_11165 8fbb50ef5e95e26ce26e7dc968d43330 199 Gene3D G3DSA:1.10.357.10 53 186 9.1E-27 T 14-10-2018 LH59_11165 8fbb50ef5e95e26ce26e7dc968d43330 199 SUPERFAMILY SSF48498 84 186 4.67E-19 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily LH59_11165 8fbb50ef5e95e26ce26e7dc968d43330 199 SUPERFAMILY SSF46689 5 74 2.84E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_11165 8fbb50ef5e95e26ce26e7dc968d43330 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 8.5E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_11165 8fbb50ef5e95e26ce26e7dc968d43330 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 8.5E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_11165 8fbb50ef5e95e26ce26e7dc968d43330 199 Gene3D G3DSA:1.10.10.60 5 51 2.4E-20 T 14-10-2018 LH59_24640 f5574f7d0389c6b4dc184a71b79cde24 427 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 9 416 1.6E-99 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit LH59_24640 f5574f7d0389c6b4dc184a71b79cde24 427 PIRSF PIRSF006066 1 427 2.2E-137 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 LH59_24640 f5574f7d0389c6b4dc184a71b79cde24 427 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 422 4.7E-118 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 LH59_15230 49a52dd2ed4c54e1aba93370f4e26278 189 SUPERFAMILY SSF55729 7 166 1.25E-31 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_15230 49a52dd2ed4c54e1aba93370f4e26278 189 Gene3D G3DSA:3.40.630.30 7 188 5.7E-32 T 14-10-2018 LH59_15230 49a52dd2ed4c54e1aba93370f4e26278 189 Pfam PF13302 Acetyltransferase (GNAT) domain 14 155 9.8E-29 T 14-10-2018 IPR000182 GNAT domain LH59_14030 d182705d4ac656aabe508413c4b6f41c 358 SUPERFAMILY SSF81345 20 353 1.22E-75 T 14-10-2018 IPR037294 ABC transporter, BtuC-like LH59_14030 d182705d4ac656aabe508413c4b6f41c 358 Gene3D G3DSA:1.10.3470.10 24 357 1.3E-93 T 14-10-2018 IPR037294 ABC transporter, BtuC-like LH59_14030 d182705d4ac656aabe508413c4b6f41c 358 Pfam PF01032 FecCD transport family 38 353 7.0E-82 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 LH59_26860 3a923676c7491a3dcbd5151f9686cc51 298 SMART SM00382 39 240 1.8E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_26860 3a923676c7491a3dcbd5151f9686cc51 298 SUPERFAMILY SSF52540 13 261 6.13E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_26860 3a923676c7491a3dcbd5151f9686cc51 298 Pfam PF00005 ABC transporter 30 191 6.2E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_26860 3a923676c7491a3dcbd5151f9686cc51 298 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 240 262 1.9E-9 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal LH59_26860 3a923676c7491a3dcbd5151f9686cc51 298 Gene3D G3DSA:3.40.50.300 2 263 4.6E-58 T 14-10-2018 LH59_04420 e5e305abfb044ff3ac3c63b81c10e029 268 Pfam PF01863 Protein of unknown function DUF45 46 260 4.0E-60 T 14-10-2018 IPR002725 Protein of unknown function DUF45 LH59_04420 e5e305abfb044ff3ac3c63b81c10e029 268 Gene3D G3DSA:3.30.2010.10 173 260 3.0E-18 T 14-10-2018 LH59_16550 db00ae8a9374e3aa09244713373ff213 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 180 5.1E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_16550 db00ae8a9374e3aa09244713373ff213 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 5.1E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_16550 db00ae8a9374e3aa09244713373ff213 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 214 5.1E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_16550 db00ae8a9374e3aa09244713373ff213 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 161 5.1E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_16550 db00ae8a9374e3aa09244713373ff213 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 117 133 5.1E-30 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_16550 db00ae8a9374e3aa09244713373ff213 234 SUPERFAMILY SSF51735 7 232 1.09E-49 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_16550 db00ae8a9374e3aa09244713373ff213 234 Gene3D G3DSA:3.40.50.720 5 232 2.0E-50 T 14-10-2018 LH59_16550 db00ae8a9374e3aa09244713373ff213 234 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 230 1.5E-32 T 14-10-2018 LH59_08730 6337524345f07033f06f8320260fb5fa 363 SUPERFAMILY SSF53756 5 355 2.18E-75 T 14-10-2018 LH59_08730 6337524345f07033f06f8320260fb5fa 363 Gene3D G3DSA:3.40.50.2000 162 335 2.7E-49 T 14-10-2018 LH59_08730 6337524345f07033f06f8320260fb5fa 363 Pfam PF00534 Glycosyl transferases group 1 168 334 2.5E-35 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 LH59_08730 6337524345f07033f06f8320260fb5fa 363 Gene3D G3DSA:3.40.50.2000 1 161 3.5E-14 T 14-10-2018 LH59_08730 6337524345f07033f06f8320260fb5fa 363 Pfam PF13439 Glycosyltransferase Family 4 12 158 4.3E-12 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 LH59_12150 58b72313010f2fce2b4cc1c1227b3b80 319 SUPERFAMILY SSF53474 3 316 2.17E-21 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_12150 58b72313010f2fce2b4cc1c1227b3b80 319 PIRSF PIRSF031982 1 319 1.0E-88 T 14-10-2018 IPR016986 Uncharacterised conserved protein UCP031982, alpha/beta hydrolase, XabL LH59_27475 a248c99e74da0b540fbc32f22f22fa91 297 Pfam PF00483 Nucleotidyl transferase 8 244 1.4E-67 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 LH59_27475 a248c99e74da0b540fbc32f22f22fa91 297 Gene3D G3DSA:3.90.550.10 2 297 7.7E-87 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases LH59_27475 a248c99e74da0b540fbc32f22f22fa91 297 SUPERFAMILY SSF53448 7 292 3.38E-91 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases LH59_27475 a248c99e74da0b540fbc32f22f22fa91 297 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 8 292 4.9E-152 T 14-10-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 LH59_01160 460c212fea6de27b382c503da7f05c3b 191 Gene3D G3DSA:3.40.30.10 37 185 1.9E-7 T 14-10-2018 LH59_01160 460c212fea6de27b382c503da7f05c3b 191 SUPERFAMILY SSF52833 47 185 8.85E-13 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_19580 6385d6d3e08e09a54aac1cae2088e800 272 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 43 260 1.8E-48 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_19580 6385d6d3e08e09a54aac1cae2088e800 272 SUPERFAMILY SSF53850 16 262 7.44E-54 T 14-10-2018 LH59_19580 6385d6d3e08e09a54aac1cae2088e800 272 Gene3D G3DSA:3.40.190.10 32 264 4.6E-53 T 14-10-2018 LH59_19580 6385d6d3e08e09a54aac1cae2088e800 272 Gene3D G3DSA:3.40.190.10 129 219 4.6E-53 T 14-10-2018 LH59_19580 6385d6d3e08e09a54aac1cae2088e800 272 SMART SM00062 42 262 9.3E-41 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_18520 d6999485c799b216364669fef53e0f41 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 326 6.6E-76 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_18520 d6999485c799b216364669fef53e0f41 329 SUPERFAMILY SSF53850 119 290 2.9E-14 T 14-10-2018 LH59_18520 d6999485c799b216364669fef53e0f41 329 Gene3D G3DSA:3.40.190.150 33 319 2.7E-104 T 14-10-2018 LH59_18520 d6999485c799b216364669fef53e0f41 329 Gene3D G3DSA:3.40.190.10 130 254 2.7E-104 T 14-10-2018 LH59_18520 d6999485c799b216364669fef53e0f41 329 PIRSF PIRSF017082 1 328 3.6E-71 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_23995 3aeca38bc124fdc7bad7dd7b57b9cf45 255 SMART SM01007 24 203 2.7E-58 T 14-10-2018 IPR001303 Class II aldolase/adducin N-terminal LH59_23995 3aeca38bc124fdc7bad7dd7b57b9cf45 255 Gene3D G3DSA:3.40.225.10 9 255 3.5E-74 T 14-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily LH59_23995 3aeca38bc124fdc7bad7dd7b57b9cf45 255 SUPERFAMILY SSF53639 18 223 8.04E-60 T 14-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily LH59_23995 3aeca38bc124fdc7bad7dd7b57b9cf45 255 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 25 203 1.1E-43 T 14-10-2018 IPR001303 Class II aldolase/adducin N-terminal LH59_08085 945ff444d7ed1067acccdbbf7a6d2127 100 SMART SM00886 2 96 5.3E-17 T 14-10-2018 IPR013097 Stress responsive alpha-beta barrel LH59_08085 945ff444d7ed1067acccdbbf7a6d2127 100 Pfam PF07876 Stress responsive A/B Barrel Domain 4 94 9.9E-11 T 14-10-2018 IPR013097 Stress responsive alpha-beta barrel LH59_08085 945ff444d7ed1067acccdbbf7a6d2127 100 Gene3D G3DSA:3.30.70.100 1 100 4.0E-20 T 14-10-2018 LH59_08085 945ff444d7ed1067acccdbbf7a6d2127 100 SUPERFAMILY SSF54909 1 96 1.93E-18 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel LH59_04115 b574a7f1b4614f7df261a61deef4c77a 178 Gene3D G3DSA:2.60.120.10 46 170 9.8E-34 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_04115 b574a7f1b4614f7df261a61deef4c77a 178 Pfam PF05995 Cysteine dioxygenase type I 69 157 3.1E-10 T 14-10-2018 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 LH59_04115 b574a7f1b4614f7df261a61deef4c77a 178 SUPERFAMILY SSF51182 24 162 9.35E-34 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_23465 50c46df102354613ae5e6d5e7055563c 514 SMART SM00155 165 192 0.041 T 14-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 LH59_23465 50c46df102354613ae5e6d5e7055563c 514 SMART SM00155 405 432 2.9E-5 T 14-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 LH59_23465 50c46df102354613ae5e6d5e7055563c 514 SUPERFAMILY SSF56024 280 478 9.64E-34 T 14-10-2018 LH59_23465 50c46df102354613ae5e6d5e7055563c 514 Pfam PF13091 PLD-like domain 79 224 4.5E-14 T 14-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 LH59_23465 50c46df102354613ae5e6d5e7055563c 514 Pfam PF13091 PLD-like domain 320 459 8.8E-23 T 14-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 LH59_23465 50c46df102354613ae5e6d5e7055563c 514 Gene3D G3DSA:3.30.870.10 51 240 2.3E-39 T 14-10-2018 LH59_23465 50c46df102354613ae5e6d5e7055563c 514 SUPERFAMILY SSF56024 44 240 3.77E-43 T 14-10-2018 LH59_23465 50c46df102354613ae5e6d5e7055563c 514 Gene3D G3DSA:3.30.870.10 293 478 6.4E-39 T 14-10-2018 LH59_20960 cc17776473f118fc0f3a6926b37d1fa3 195 Pfam PF04229 GrpB protein 30 186 1.5E-49 T 14-10-2018 IPR007344 GrpB/Dephospho-CoA kinase LH59_20960 cc17776473f118fc0f3a6926b37d1fa3 195 Gene3D G3DSA:3.30.460.10 26 192 1.2E-45 T 14-10-2018 LH59_20960 cc17776473f118fc0f3a6926b37d1fa3 195 SUPERFAMILY SSF81301 31 190 3.27E-44 T 14-10-2018 LH59_15140 39b6f7e6596d0ad93374966a1ad74ec0 306 SUPERFAMILY SSF46689 256 300 5.38E-7 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_15140 39b6f7e6596d0ad93374966a1ad74ec0 306 Gene3D G3DSA:1.10.10.60 199 305 8.1E-21 T 14-10-2018 LH59_15140 39b6f7e6596d0ad93374966a1ad74ec0 306 SMART SM00342 220 302 6.1E-17 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_15140 39b6f7e6596d0ad93374966a1ad74ec0 306 SUPERFAMILY SSF46689 203 253 6.99E-5 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_15140 39b6f7e6596d0ad93374966a1ad74ec0 306 Pfam PF12833 Helix-turn-helix domain 226 300 2.1E-17 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_26000 d5ba40834892aa45f35bc775e3e62da0 300 Pfam PF02653 Branched-chain amino acid transport system / permease component 14 283 1.5E-34 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_09020 ebf045738d00cc56b935192c1b1bd421 446 Gene3D G3DSA:3.90.1150.10 16 437 8.3E-159 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_09020 ebf045738d00cc56b935192c1b1bd421 446 Pfam PF00202 Aminotransferase class-III 16 436 2.0E-105 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LH59_09020 ebf045738d00cc56b935192c1b1bd421 446 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 239 276 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LH59_09020 ebf045738d00cc56b935192c1b1bd421 446 PIRSF PIRSF000521 18 438 3.9E-37 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LH59_09020 ebf045738d00cc56b935192c1b1bd421 446 Gene3D G3DSA:3.40.640.10 50 328 8.3E-159 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_09020 ebf045738d00cc56b935192c1b1bd421 446 SUPERFAMILY SSF53383 9 438 5.67E-127 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_02690 74c483b599898c293aff2d775d0de011 303 Pfam PF02653 Branched-chain amino acid transport system / permease component 7 271 2.5E-40 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_26785 2827a66e6feeee49db7f5f0dd44c776a 230 Pfam PF00156 Phosphoribosyl transferase domain 55 176 2.5E-15 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 LH59_26785 2827a66e6feeee49db7f5f0dd44c776a 230 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 18 203 3.2E-58 T 14-10-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 LH59_26785 2827a66e6feeee49db7f5f0dd44c776a 230 SUPERFAMILY SSF53271 11 227 1.3E-43 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like LH59_26785 2827a66e6feeee49db7f5f0dd44c776a 230 Gene3D G3DSA:3.40.50.2020 9 230 5.3E-69 T 14-10-2018 LH59_26785 2827a66e6feeee49db7f5f0dd44c776a 230 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 230 32.714 T 14-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 LH59_27830 7c2389d26e780377f99d624215594607 298 Pfam PF00561 alpha/beta hydrolase fold 36 271 7.8E-20 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_27830 7c2389d26e780377f99d624215594607 298 SUPERFAMILY SSF53474 12 278 2.11E-48 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_27830 7c2389d26e780377f99d624215594607 298 Gene3D G3DSA:3.40.50.1820 3 287 2.8E-71 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_19635 21ded6db5a0a2e03d52292ba707070cf 399 SUPERFAMILY SSF53822 27 394 1.95E-74 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_19635 21ded6db5a0a2e03d52292ba707070cf 399 Pfam PF13458 Periplasmic binding protein 27 381 1.6E-59 T 14-10-2018 IPR028081 Leucine-binding protein domain LH59_19635 21ded6db5a0a2e03d52292ba707070cf 399 Gene3D G3DSA:3.40.50.2300 27 345 2.0E-77 T 14-10-2018 LH59_19635 21ded6db5a0a2e03d52292ba707070cf 399 Gene3D G3DSA:3.40.50.2300 143 281 2.0E-77 T 14-10-2018 LH59_24765 972e707f24ebd2f2944a530048af3952 498 Gene3D G3DSA:3.40.309.10 250 451 1.0E-154 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 LH59_24765 972e707f24ebd2f2944a530048af3952 498 Pfam PF00171 Aldehyde dehydrogenase family 19 478 1.2E-141 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 LH59_24765 972e707f24ebd2f2944a530048af3952 498 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 275 286 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 LH59_24765 972e707f24ebd2f2944a530048af3952 498 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 6 482 2.2E-213 T 14-10-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00640+1.2.1.27|MetaCyc: PWY-5642|Reactome: R-HSA-70895 LH59_24765 972e707f24ebd2f2944a530048af3952 498 SUPERFAMILY SSF53720 3 483 7.98E-153 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 LH59_24765 972e707f24ebd2f2944a530048af3952 498 Gene3D G3DSA:3.40.605.10 25 459 1.0E-154 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 LH59_23090 c2b00c09ae1f9777411ad78178fda925 417 Pfam PF13433 Periplasmic binding protein domain 32 408 1.3E-171 T 14-10-2018 LH59_23090 c2b00c09ae1f9777411ad78178fda925 417 TIGRFAM TIGR03407 urea_ABC_UrtA: urea ABC transporter, urea binding protein 32 405 1.6E-178 T 14-10-2018 IPR017777 Urea ABC transporter, substrate-binding protein UrtA-like LH59_23090 c2b00c09ae1f9777411ad78178fda925 417 Gene3D G3DSA:3.40.50.2300 147 396 4.9E-138 T 14-10-2018 LH59_23090 c2b00c09ae1f9777411ad78178fda925 417 Gene3D G3DSA:3.40.50.2300 34 376 4.9E-138 T 14-10-2018 LH59_23090 c2b00c09ae1f9777411ad78178fda925 417 SUPERFAMILY SSF53822 31 409 2.07E-90 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_15930 2a5d7fc6067640534fae378b93191311 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 8.9E-16 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_15930 2a5d7fc6067640534fae378b93191311 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.2E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_15930 2a5d7fc6067640534fae378b93191311 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.2E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_15930 2a5d7fc6067640534fae378b93191311 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.2E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_15930 2a5d7fc6067640534fae378b93191311 299 Pfam PF03466 LysR substrate binding domain 89 289 1.0E-30 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_15930 2a5d7fc6067640534fae378b93191311 299 Gene3D G3DSA:1.10.10.10 1 90 1.8E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_15930 2a5d7fc6067640534fae378b93191311 299 Gene3D G3DSA:3.40.190.290 91 295 2.1E-30 T 14-10-2018 LH59_15930 2a5d7fc6067640534fae378b93191311 299 SUPERFAMILY SSF53850 90 293 2.58E-31 T 14-10-2018 LH59_15930 2a5d7fc6067640534fae378b93191311 299 SUPERFAMILY SSF46785 1 80 7.62E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_16730 5157608184ba32a6f6e54c22ef4d6081 321 PIRSF PIRSF017082 1 321 1.6E-71 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_16730 5157608184ba32a6f6e54c22ef4d6081 321 Gene3D G3DSA:3.40.190.10 122 246 9.3E-97 T 14-10-2018 LH59_16730 5157608184ba32a6f6e54c22ef4d6081 321 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 44 315 2.8E-66 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_16730 5157608184ba32a6f6e54c22ef4d6081 321 Gene3D G3DSA:3.40.190.150 24 311 9.3E-97 T 14-10-2018 LH59_16730 5157608184ba32a6f6e54c22ef4d6081 321 SUPERFAMILY SSF53850 105 283 6.29E-12 T 14-10-2018 LH59_14785 21f7026c91a93ba9fc53b28daa86f1e2 297 Pfam PF00892 EamA-like transporter family 158 292 4.2E-14 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_14785 21f7026c91a93ba9fc53b28daa86f1e2 297 Pfam PF00892 EamA-like transporter family 19 144 1.1E-15 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_14785 21f7026c91a93ba9fc53b28daa86f1e2 297 SUPERFAMILY SSF103481 46 146 1.57E-13 T 14-10-2018 LH59_14785 21f7026c91a93ba9fc53b28daa86f1e2 297 SUPERFAMILY SSF103481 195 295 3.92E-12 T 14-10-2018 LH59_05525 4e33604f5b55e4ca5c03be05d622ccca 263 SUPERFAMILY SSF56317 2 258 3.92E-66 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily LH59_05525 4e33604f5b55e4ca5c03be05d622ccca 263 Gene3D G3DSA:3.60.110.10 1 259 5.8E-70 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily LH59_05525 4e33604f5b55e4ca5c03be05d622ccca 263 Pfam PF00795 Carbon-nitrogen hydrolase 4 246 7.9E-39 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 LH59_05525 4e33604f5b55e4ca5c03be05d622ccca 263 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 144 164 - T 14-10-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site LH59_18080 1ce48e126378ea3b90ddd3a88d41ec93 488 Gene3D G3DSA:3.40.309.10 248 444 6.0E-176 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 LH59_18080 1ce48e126378ea3b90ddd3a88d41ec93 488 TIGRFAM TIGR02299 HpaE: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase 3 487 2.1E-221 T 14-10-2018 IPR011985 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase GO:0018480|GO:1901023 LH59_18080 1ce48e126378ea3b90ddd3a88d41ec93 488 Pfam PF00171 Aldehyde dehydrogenase family 15 474 4.4E-169 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 LH59_18080 1ce48e126378ea3b90ddd3a88d41ec93 488 Gene3D G3DSA:3.40.605.10 7 472 6.0E-176 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 LH59_18080 1ce48e126378ea3b90ddd3a88d41ec93 488 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 243 250 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 LH59_18080 1ce48e126378ea3b90ddd3a88d41ec93 488 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 271 282 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 LH59_18080 1ce48e126378ea3b90ddd3a88d41ec93 488 SUPERFAMILY SSF53720 3 480 7.72E-164 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 LH59_03410 39127192f3d89f4e3ff5c80a365be890 212 PIRSF PIRSF006324 1 209 1.3E-52 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 LH59_03410 39127192f3d89f4e3ff5c80a365be890 212 Pfam PF01810 LysE type translocator 17 206 1.6E-31 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 LH59_21445 3fb0abfb857c3305425d708fb43faf11 382 Pfam PF07690 Major Facilitator Superfamily 5 344 1.3E-38 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_21445 3fb0abfb857c3305425d708fb43faf11 382 SUPERFAMILY SSF103473 3 372 2.62E-54 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_21445 3fb0abfb857c3305425d708fb43faf11 382 Gene3D G3DSA:1.20.1720.10 1 374 1.9E-101 T 14-10-2018 LH59_21445 3fb0abfb857c3305425d708fb43faf11 382 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 2 374 7.2E-92 T 14-10-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0006855|GO:0015238|GO:0016021 LH59_26720 491cb5a5392369f265c8a9089d095b4b 248 Gene3D G3DSA:1.10.150.450 31 100 2.0E-6 T 14-10-2018 LH59_26720 491cb5a5392369f265c8a9089d095b4b 248 SUPERFAMILY SSF56784 27 239 1.04E-32 T 14-10-2018 IPR036412 HAD-like superfamily LH59_26720 491cb5a5392369f265c8a9089d095b4b 248 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 29 211 1.3E-14 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 LH59_26720 491cb5a5392369f265c8a9089d095b4b 248 Pfam PF13419 Haloacid dehalogenase-like hydrolase 30 211 4.9E-11 T 14-10-2018 LH59_26720 491cb5a5392369f265c8a9089d095b4b 248 TIGRFAM TIGR01993 Pyr-5-nucltdase: pyrimidine 5'-nucleotidase 28 210 3.0E-45 T 14-10-2018 IPR010237 Pyrimidine 5-nucleotidase LH59_26720 491cb5a5392369f265c8a9089d095b4b 248 Gene3D G3DSA:3.40.50.1000 101 242 1.4E-22 T 14-10-2018 IPR023214 HAD superfamily LH59_01310 17c6bf4b95a4a78fbd9c7e2de1766bd5 216 Gene3D G3DSA:3.40.50.10610 24 187 6.6E-64 T 14-10-2018 LH59_01310 17c6bf4b95a4a78fbd9c7e2de1766bd5 216 Pfam PF05643 Putative bacterial lipoprotein (DUF799) 10 208 1.5E-87 T 14-10-2018 IPR008517 Protein of unknown function DUF799 LH59_25645 9f5b2e01b5cd9e950cb89b1f4e1f2b83 485 SUPERFAMILY SSF160935 48 482 2.88E-109 T 14-10-2018 LH59_25645 9f5b2e01b5cd9e950cb89b1f4e1f2b83 485 Pfam PF06863 Protein of unknown function (DUF1254) 90 222 4.0E-39 T 14-10-2018 IPR010679 Domain of unknown function DUF1254 LH59_25645 9f5b2e01b5cd9e950cb89b1f4e1f2b83 485 Gene3D G3DSA:2.60.120.1600 361 484 3.4E-38 T 14-10-2018 LH59_25645 9f5b2e01b5cd9e950cb89b1f4e1f2b83 485 Pfam PF06742 Protein of unknown function (DUF1214) 358 467 1.2E-30 T 14-10-2018 IPR010621 Domain of unknown function DUF1214 LH59_04625 f2cd98cb27d18a6d66d5363179af527e 296 Gene3D G3DSA:3.40.190.10 93 274 1.4E-23 T 14-10-2018 LH59_04625 f2cd98cb27d18a6d66d5363179af527e 296 Gene3D G3DSA:1.10.10.10 1 92 2.4E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_04625 f2cd98cb27d18a6d66d5363179af527e 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.1E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_04625 f2cd98cb27d18a6d66d5363179af527e 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.1E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_04625 f2cd98cb27d18a6d66d5363179af527e 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.1E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_04625 f2cd98cb27d18a6d66d5363179af527e 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.7E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_04625 f2cd98cb27d18a6d66d5363179af527e 296 SUPERFAMILY SSF46785 1 110 7.48E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_04625 f2cd98cb27d18a6d66d5363179af527e 296 Gene3D G3DSA:3.40.190.10 164 261 1.4E-23 T 14-10-2018 LH59_04625 f2cd98cb27d18a6d66d5363179af527e 296 SUPERFAMILY SSF53850 89 289 3.67E-31 T 14-10-2018 LH59_04625 f2cd98cb27d18a6d66d5363179af527e 296 Pfam PF03466 LysR substrate binding domain 87 287 4.7E-29 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_02375 8231c0f14cb185d536534080c9ef129e 251 Pfam PF07702 UTRA domain 103 240 4.1E-32 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LH59_02375 8231c0f14cb185d536534080c9ef129e 251 SUPERFAMILY SSF64288 67 242 2.2E-35 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily LH59_02375 8231c0f14cb185d536534080c9ef129e 251 Gene3D G3DSA:1.10.10.10 12 79 4.5E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_02375 8231c0f14cb185d536534080c9ef129e 251 SUPERFAMILY SSF46785 13 88 4.92E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_02375 8231c0f14cb185d536534080c9ef129e 251 SMART SM00345 19 78 3.8E-20 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_02375 8231c0f14cb185d536534080c9ef129e 251 SMART SM00866 98 240 5.9E-32 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 LH59_02375 8231c0f14cb185d536534080c9ef129e 251 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 78 2.8E-20 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_02375 8231c0f14cb185d536534080c9ef129e 251 Gene3D G3DSA:3.40.1410.10 85 242 2.1E-42 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily LH59_22105 9e31f93a5777bcfaa713132ead70411f 142 SUPERFAMILY SSF88723 2 138 1.85E-26 T 14-10-2018 IPR029060 PIN-like domain superfamily LH59_22105 9e31f93a5777bcfaa713132ead70411f 142 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 134 10.125 T 14-10-2018 IPR022907 VapC family GO:0004540 LH59_22105 9e31f93a5777bcfaa713132ead70411f 142 Gene3D G3DSA:3.40.50.1010 2 140 6.5E-37 T 14-10-2018 LH59_22105 9e31f93a5777bcfaa713132ead70411f 142 Pfam PF01850 PIN domain 4 123 1.4E-11 T 14-10-2018 IPR002716 PIN domain LH59_18995 c2d4b822225b7031fc940c8bf9ff07cf 261 SUPERFAMILY SSF53639 25 236 1.2E-65 T 14-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily LH59_18995 c2d4b822225b7031fc940c8bf9ff07cf 261 Gene3D G3DSA:3.40.225.10 16 257 2.2E-55 T 14-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily LH59_18995 c2d4b822225b7031fc940c8bf9ff07cf 261 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 34 211 1.8E-38 T 14-10-2018 IPR001303 Class II aldolase/adducin N-terminal LH59_18995 c2d4b822225b7031fc940c8bf9ff07cf 261 SMART SM01007 33 211 2.8E-47 T 14-10-2018 IPR001303 Class II aldolase/adducin N-terminal LH59_11040 c3a8bcfeab3657b9c8f4c74a268e7e80 870 Pfam PF03958 Bacterial type II/III secretion system short domain 291 427 9.6E-11 T 14-10-2018 IPR005644 NolW-like LH59_11040 c3a8bcfeab3657b9c8f4c74a268e7e80 870 Pfam PF03958 Bacterial type II/III secretion system short domain 154 213 4.0E-13 T 14-10-2018 IPR005644 NolW-like LH59_11040 c3a8bcfeab3657b9c8f4c74a268e7e80 870 Pfam PF03958 Bacterial type II/III secretion system short domain 218 285 1.0E-10 T 14-10-2018 IPR005644 NolW-like LH59_11040 c3a8bcfeab3657b9c8f4c74a268e7e80 870 TIGRFAM TIGR02517 type_II_gspD: type II secretion system protein D 36 689 1.2E-185 T 14-10-2018 IPR013356 Type II secretion system GspD GO:0008565|GO:0015627|GO:0015628|GO:0019867 LH59_11040 c3a8bcfeab3657b9c8f4c74a268e7e80 870 PRINTS PR00811 Bacterial general secretion pathway protein D signature 545 555 7.8E-29 T 14-10-2018 IPR001775 GspD/PilQ family LH59_11040 c3a8bcfeab3657b9c8f4c74a268e7e80 870 PRINTS PR00811 Bacterial general secretion pathway protein D signature 667 681 7.8E-29 T 14-10-2018 IPR001775 GspD/PilQ family LH59_11040 c3a8bcfeab3657b9c8f4c74a268e7e80 870 PRINTS PR00811 Bacterial general secretion pathway protein D signature 427 437 7.8E-29 T 14-10-2018 IPR001775 GspD/PilQ family LH59_11040 c3a8bcfeab3657b9c8f4c74a268e7e80 870 PRINTS PR00811 Bacterial general secretion pathway protein D signature 510 534 7.8E-29 T 14-10-2018 IPR001775 GspD/PilQ family LH59_11040 c3a8bcfeab3657b9c8f4c74a268e7e80 870 PRINTS PR00811 Bacterial general secretion pathway protein D signature 644 662 7.8E-29 T 14-10-2018 IPR001775 GspD/PilQ family LH59_11040 c3a8bcfeab3657b9c8f4c74a268e7e80 870 Gene3D G3DSA:3.30.1370.120 214 284 7.0E-10 T 14-10-2018 IPR038591 NolW-like superfamily LH59_11040 c3a8bcfeab3657b9c8f4c74a268e7e80 870 Gene3D G3DSA:3.30.1370.120 26 211 1.1E-50 T 14-10-2018 IPR038591 NolW-like superfamily LH59_11040 c3a8bcfeab3657b9c8f4c74a268e7e80 870 SUPERFAMILY SSF110997 799 867 1.96E-5 T 14-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 LH59_11040 c3a8bcfeab3657b9c8f4c74a268e7e80 870 Pfam PF00263 Bacterial type II and III secretion system protein 514 680 5.9E-51 T 14-10-2018 IPR004846 Type II/III secretion system GO:0009306 LH59_01655 f42615e843607fa478c33580bfba9d84 269 SUPERFAMILY SSF52540 17 242 1.27E-77 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_01655 f42615e843607fa478c33580bfba9d84 269 Gene3D G3DSA:3.40.50.300 15 265 5.6E-80 T 14-10-2018 LH59_01655 f42615e843607fa478c33580bfba9d84 269 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_01655 f42615e843607fa478c33580bfba9d84 269 Pfam PF00005 ABC transporter 38 186 3.8E-37 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_01655 f42615e843607fa478c33580bfba9d84 269 SMART SM00382 46 235 6.7E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_10840 91cdf390276e8d7db20d46819c0a4eb8 402 SUPERFAMILY SSF103473 24 392 1.7E-51 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_10840 91cdf390276e8d7db20d46819c0a4eb8 402 Pfam PF07690 Major Facilitator Superfamily 28 247 5.5E-22 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_10840 91cdf390276e8d7db20d46819c0a4eb8 402 Pfam PF07690 Major Facilitator Superfamily 258 389 1.9E-10 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_10840 91cdf390276e8d7db20d46819c0a4eb8 402 Gene3D G3DSA:1.20.1250.20 23 393 2.4E-44 T 14-10-2018 LH59_02815 e5a21e664205a6018b4bed5d202d63a9 332 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 55 329 1.3E-84 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_02815 e5a21e664205a6018b4bed5d202d63a9 332 Gene3D G3DSA:3.40.190.150 35 322 2.1E-106 T 14-10-2018 LH59_02815 e5a21e664205a6018b4bed5d202d63a9 332 Gene3D G3DSA:3.40.190.10 133 257 2.1E-106 T 14-10-2018 LH59_02815 e5a21e664205a6018b4bed5d202d63a9 332 SUPERFAMILY SSF53850 121 294 4.56E-11 T 14-10-2018 LH59_02815 e5a21e664205a6018b4bed5d202d63a9 332 PIRSF PIRSF017082 1 332 3.7E-85 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_13935 2d381e63a8edb43b5885964a8b426c6c 364 Gene3D G3DSA:3.40.190.10 32 346 2.8E-127 T 14-10-2018 LH59_13935 2d381e63a8edb43b5885964a8b426c6c 364 SUPERFAMILY SSF53850 43 258 3.02E-38 T 14-10-2018 LH59_13935 2d381e63a8edb43b5885964a8b426c6c 364 Gene3D G3DSA:3.40.190.10 123 225 2.8E-127 T 14-10-2018 LH59_13935 2d381e63a8edb43b5885964a8b426c6c 364 Pfam PF09084 NMT1/THI5 like 65 256 1.3E-15 T 14-10-2018 IPR015168 SsuA/THI5-like LH59_02165 3ef3f0e780fd286e5378f14e94e9f54f 323 Gene3D G3DSA:3.20.20.70 6 321 3.6E-70 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_02165 3ef3f0e780fd286e5378f14e94e9f54f 323 Pfam PF03060 Nitronate monooxygenase 84 250 2.8E-21 T 14-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 LH59_02165 3ef3f0e780fd286e5378f14e94e9f54f 323 SUPERFAMILY SSF51412 13 307 1.54E-57 T 14-10-2018 LH59_27105 31bc5dc8979017cc273d8280cf7016cc 434 ProSitePatterns PS00216 Sugar transport proteins signature 1. 84 100 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 LH59_27105 31bc5dc8979017cc273d8280cf7016cc 434 Gene3D G3DSA:1.20.1250.20 21 434 9.5E-69 T 14-10-2018 LH59_27105 31bc5dc8979017cc273d8280cf7016cc 434 ProSitePatterns PS00217 Sugar transport proteins signature 2. 134 159 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 LH59_27105 31bc5dc8979017cc273d8280cf7016cc 434 SUPERFAMILY SSF103473 23 433 2.22E-67 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_27105 31bc5dc8979017cc273d8280cf7016cc 434 Pfam PF07690 Major Facilitator Superfamily 33 377 1.4E-29 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_18385 a74456823d0ee80789806d1752b06ae9 493 Gene3D G3DSA:3.90.1150.10 319 469 2.1E-19 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_18385 a74456823d0ee80789806d1752b06ae9 493 SUPERFAMILY SSF53383 43 462 4.78E-74 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_18385 a74456823d0ee80789806d1752b06ae9 493 Gene3D G3DSA:3.40.640.10 65 318 1.2E-46 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_18385 a74456823d0ee80789806d1752b06ae9 493 Pfam PF00266 Aminotransferase class-V 51 412 3.3E-46 T 14-10-2018 IPR000192 Aminotransferase class V domain LH59_01630 0b7edca2a52ac8a8d24935ccd5c7fa18 197 Pfam PF03358 NADPH-dependent FMN reductase 1 142 6.9E-32 T 14-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 LH59_01630 0b7edca2a52ac8a8d24935ccd5c7fa18 197 Gene3D G3DSA:3.40.50.360 1 182 1.5E-48 T 14-10-2018 IPR029039 Flavoprotein-like superfamily LH59_01630 0b7edca2a52ac8a8d24935ccd5c7fa18 197 SUPERFAMILY SSF52218 1 169 1.84E-33 T 14-10-2018 IPR029039 Flavoprotein-like superfamily LH59_01630 0b7edca2a52ac8a8d24935ccd5c7fa18 197 TIGRFAM TIGR03567 FMN_reduc_SsuE: FMN reductase 3 171 4.9E-68 T 14-10-2018 IPR020048 NADPH-dependent FMN reductase, SsuE GO:0008752|GO:0046306|GO:0055114 KEGG: 00740+1.5.1.38|MetaCyc: PWY-7723 LH59_18755 8f79443a9d9bfa2ea9e508602604ea17 256 Pfam PF12833 Helix-turn-helix domain 176 253 1.1E-20 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_18755 8f79443a9d9bfa2ea9e508602604ea17 256 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 205 248 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 LH59_18755 8f79443a9d9bfa2ea9e508602604ea17 256 Pfam PF02311 AraC-like ligand binding domain 24 106 3.8E-5 T 14-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 LH59_18755 8f79443a9d9bfa2ea9e508602604ea17 256 SUPERFAMILY SSF51182 13 191 1.11E-16 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_18755 8f79443a9d9bfa2ea9e508602604ea17 256 SUPERFAMILY SSF46689 210 254 8.96E-7 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_18755 8f79443a9d9bfa2ea9e508602604ea17 256 Gene3D G3DSA:2.60.120.10 13 101 1.2E-7 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_18755 8f79443a9d9bfa2ea9e508602604ea17 256 SMART SM00342 170 252 8.0E-15 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_18755 8f79443a9d9bfa2ea9e508602604ea17 256 Gene3D G3DSA:1.10.10.60 160 256 6.4E-19 T 14-10-2018 LH59_06350 6b1ef159c8ba5aae6c388c026f7cc2b6 236 SMART SM00382 30 215 1.1E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_06350 6b1ef159c8ba5aae6c388c026f7cc2b6 236 Pfam PF00005 ABC transporter 21 163 5.1E-22 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_06350 6b1ef159c8ba5aae6c388c026f7cc2b6 236 Gene3D G3DSA:3.40.50.300 2 236 6.9E-51 T 14-10-2018 LH59_06350 6b1ef159c8ba5aae6c388c026f7cc2b6 236 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_06350 6b1ef159c8ba5aae6c388c026f7cc2b6 236 SUPERFAMILY SSF52540 4 229 2.92E-53 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_15470 dcd551c78c8414fb24ff00c2ab2e4e4e 168 Gene3D G3DSA:2.60.40.4150 17 145 3.1E-31 T 14-10-2018 IPR038706 Type VI secretion protein SciN-like superfamily LH59_15470 dcd551c78c8414fb24ff00c2ab2e4e4e 168 TIGRFAM TIGR03352 VI_chp_3: type VI secretion lipoprotein, VC_A0113 family 12 140 1.2E-26 T 14-10-2018 IPR017734 Type VI secretion system, lipoprotein SciN LH59_15470 dcd551c78c8414fb24ff00c2ab2e4e4e 168 Pfam PF12790 Type VI secretion lipoprotein, VasD, EvfM, TssJ, VC_A0113 16 136 2.5E-28 T 14-10-2018 IPR017734 Type VI secretion system, lipoprotein SciN LH59_21390 f8c458482d794f72ba3b3637142c4a6a 338 TIGRFAM TIGR02634 xylF: D-xylose ABC transporter, D-xylose-binding protein 34 335 1.8E-135 T 14-10-2018 IPR013456 D-xylose ABC transporter, substrate-binding protein GO:0015753|GO:0048029 LH59_21390 f8c458482d794f72ba3b3637142c4a6a 338 Gene3D G3DSA:3.40.50.2300 135 322 2.2E-113 T 14-10-2018 LH59_21390 f8c458482d794f72ba3b3637142c4a6a 338 Gene3D G3DSA:3.40.50.2300 35 311 2.2E-113 T 14-10-2018 LH59_21390 f8c458482d794f72ba3b3637142c4a6a 338 SUPERFAMILY SSF53822 32 322 1.18E-72 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_21390 f8c458482d794f72ba3b3637142c4a6a 338 Pfam PF13407 Periplasmic binding protein domain 35 291 2.3E-65 T 14-10-2018 IPR025997 Periplasmic binding protein LH59_20160 81e808d46a023903a5433f30bd1ea9fe 260 SUPERFAMILY SSF52467 11 257 7.77E-82 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily LH59_20160 81e808d46a023903a5433f30bd1ea9fe 260 Gene3D G3DSA:3.30.1600.10 36 180 8.2E-84 T 14-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily LH59_20160 81e808d46a023903a5433f30bd1ea9fe 260 Hamap MF_01121 NAD-dependent protein deacylase [cobB]. 20 256 58.651 T 14-10-2018 IPR027546 Sirtuin, class III GO:0036054|GO:0036055|GO:0070403 Reactome: R-HSA-2151201 LH59_20160 81e808d46a023903a5433f30bd1ea9fe 260 Gene3D G3DSA:3.40.50.1220 18 254 8.2E-84 T 14-10-2018 LH59_20160 81e808d46a023903a5433f30bd1ea9fe 260 Pfam PF02146 Sir2 family 27 210 7.7E-51 T 14-10-2018 IPR003000 Sirtuin family GO:0070403 LH59_18610 2cdafa5e016e63fb42281dcdf9ea407b 262 Gene3D G3DSA:3.10.310.10 118 250 8.0E-92 T 14-10-2018 LH59_18610 2cdafa5e016e63fb42281dcdf9ea407b 262 SUPERFAMILY SSF54506 4 262 2.49E-81 T 14-10-2018 LH59_18610 2cdafa5e016e63fb42281dcdf9ea407b 262 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 5 259 2.1E-36 T 14-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 LH59_18610 2cdafa5e016e63fb42281dcdf9ea407b 262 Pfam PF02567 Phenazine biosynthesis-like protein 9 256 7.1E-56 T 14-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 LH59_18610 2cdafa5e016e63fb42281dcdf9ea407b 262 PIRSF PIRSF016184 1 262 5.2E-60 T 14-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 LH59_18610 2cdafa5e016e63fb42281dcdf9ea407b 262 Gene3D G3DSA:3.10.310.10 7 254 8.0E-92 T 14-10-2018 LH59_04930 554773d5bc6bd4f85d5f71f4773e4e4d 272 SUPERFAMILY SSF110710 8 266 3.14E-81 T 14-10-2018 IPR028345 Aminoglycoside 3-N-acetyltransferase-like LH59_04930 554773d5bc6bd4f85d5f71f4773e4e4d 272 Pfam PF02522 Aminoglycoside 3-N-acetyltransferase 35 264 1.2E-72 T 14-10-2018 IPR003679 Aminoglycoside N(3)-acetyltransferase GO:0046353|GO:0046677 LH59_26765 b4efe5cf0c22b4c013e7600e20ef4e1e 102 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 2 102 22.956 T 14-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 LH59_26765 b4efe5cf0c22b4c013e7600e20ef4e1e 102 SUPERFAMILY SSF141000 3 100 5.1E-24 T 14-10-2018 IPR036113 Glu-tRNAGln amidotransferase superfamily, subunit C GO:0006450 LH59_26765 b4efe5cf0c22b4c013e7600e20ef4e1e 102 Gene3D G3DSA:1.10.20.60 1 100 9.6E-23 T 14-10-2018 LH59_26765 b4efe5cf0c22b4c013e7600e20ef4e1e 102 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 102 3.9E-25 T 14-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 LH59_26765 b4efe5cf0c22b4c013e7600e20ef4e1e 102 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 19 97 6.0E-20 T 14-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 LH59_19105 22fcd18e6c67bc4db44ef8ec4ec38565 369 Pfam PF01757 Acyltransferase family 8 349 1.9E-24 T 14-10-2018 IPR002656 Acyltransferase 3 GO:0016747 LH59_02430 2c33213a11c1fc5b13ec7aeccca73698 291 SUPERFAMILY SSF53850 86 281 8.82E-33 T 14-10-2018 LH59_02430 2c33213a11c1fc5b13ec7aeccca73698 291 Gene3D G3DSA:3.40.190.290 88 278 6.8E-35 T 14-10-2018 LH59_02430 2c33213a11c1fc5b13ec7aeccca73698 291 SUPERFAMILY SSF46785 5 108 7.0E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_02430 2c33213a11c1fc5b13ec7aeccca73698 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 4.2E-19 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_02430 2c33213a11c1fc5b13ec7aeccca73698 291 Pfam PF03466 LysR substrate binding domain 84 263 4.2E-36 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_02430 2c33213a11c1fc5b13ec7aeccca73698 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 17 28 1.8E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_02430 2c33213a11c1fc5b13ec7aeccca73698 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 49 1.8E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_02430 2c33213a11c1fc5b13ec7aeccca73698 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 28 38 1.8E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_02430 2c33213a11c1fc5b13ec7aeccca73698 291 Gene3D G3DSA:1.10.10.10 1 82 1.3E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_11410 8f7ee10eb474ec32b59e497c67ef9da9 495 Pfam PF00460 Flagella basal body rod protein 6 33 2.5E-10 T 14-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 LH59_11410 8f7ee10eb474ec32b59e497c67ef9da9 495 Gene3D G3DSA:2.60.98.20 237 377 4.0E-21 T 14-10-2018 IPR037058 Flagellar hook protein FlgE superfamily LH59_11410 8f7ee10eb474ec32b59e497c67ef9da9 495 SUPERFAMILY SSF117143 73 456 2.22E-64 T 14-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like LH59_11410 8f7ee10eb474ec32b59e497c67ef9da9 495 Pfam PF07559 Flagellar basal body protein FlaE 255 376 7.6E-18 T 14-10-2018 IPR011491 Flagellar hook protein FlgE LH59_11410 8f7ee10eb474ec32b59e497c67ef9da9 495 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 416 494 2.5E-20 T 14-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain LH59_11410 8f7ee10eb474ec32b59e497c67ef9da9 495 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 191 477 6.5E-49 T 14-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G LH59_11410 8f7ee10eb474ec32b59e497c67ef9da9 495 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 2 230 1.3E-37 T 14-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G LH59_09225 bf290955e65b0e9eb2cadd19c9486c5b 180 Pfam PF00156 Phosphoribosyl transferase domain 16 161 1.5E-24 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 LH59_09225 bf290955e65b0e9eb2cadd19c9486c5b 180 Gene3D G3DSA:3.40.50.2020 9 177 2.9E-33 T 14-10-2018 LH59_09225 bf290955e65b0e9eb2cadd19c9486c5b 180 SUPERFAMILY SSF53271 6 176 4.85E-35 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like LH59_18660 88397f7cccb229716bb436fad15ab908 751 SUPERFAMILY SSF52540 130 354 3.02E-28 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_18660 88397f7cccb229716bb436fad15ab908 751 Gene3D G3DSA:3.40.50.300 141 384 1.1E-32 T 14-10-2018 LH59_18660 88397f7cccb229716bb436fad15ab908 751 Pfam PF00350 Dynamin family 141 315 5.3E-16 T 14-10-2018 IPR022812 Dynamin superfamily LH59_05680 f37e5939eed5dfdc627d91ee2d4d721c 405 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 21 399 2.5E-133 T 14-10-2018 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 LH59_05680 f37e5939eed5dfdc627d91ee2d4d721c 405 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 17 305 4.6E-76 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme LH59_05680 f37e5939eed5dfdc627d91ee2d4d721c 405 Gene3D G3DSA:3.40.50.1100 7 309 3.4E-112 T 14-10-2018 LH59_05680 f37e5939eed5dfdc627d91ee2d4d721c 405 Gene3D G3DSA:3.40.50.1100 50 146 3.4E-112 T 14-10-2018 LH59_05680 f37e5939eed5dfdc627d91ee2d4d721c 405 SUPERFAMILY SSF53686 5 354 2.88E-92 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme LH59_06805 466f0c4150acb6aba592c161eef444ff 142 Pfam PF04977 Septum formation initiator 11 88 3.7E-25 T 14-10-2018 IPR007060 Septum formation initiator FtsL/DivIC LH59_06805 466f0c4150acb6aba592c161eef444ff 142 Hamap MF_00599 Cell division protein FtsB [ftsB]. 1 90 35.68 T 14-10-2018 IPR023081 Cell division protein FtsB LH59_14920 ca45fd0896ff334e234ca2863a33e86f 147 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 4 146 2.9E-36 T 14-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 LH59_14920 ca45fd0896ff334e234ca2863a33e86f 147 Gene3D G3DSA:3.30.479.10 1 90 3.9E-24 T 14-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 LH59_14920 ca45fd0896ff334e234ca2863a33e86f 147 Gene3D G3DSA:3.30.479.10 91 147 6.2E-11 T 14-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 LH59_14920 ca45fd0896ff334e234ca2863a33e86f 147 PIRSF PIRSF006113 1 81 7.9E-18 T 14-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 LH59_14920 ca45fd0896ff334e234ca2863a33e86f 147 PIRSF PIRSF006113 88 147 0.15 T 14-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 LH59_14920 ca45fd0896ff334e234ca2863a33e86f 147 SUPERFAMILY SSF55620 1 145 2.33E-40 T 14-10-2018 LH59_14920 ca45fd0896ff334e234ca2863a33e86f 147 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 4 117 2.4E-29 T 14-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 LH59_07070 48b2d3143907f4e329f929ce42ca0a5d 189 Pfam PF05233 PHB accumulation regulatory domain 126 165 1.4E-14 T 14-10-2018 IPR007897 PHB accumulation regulatory LH59_07070 48b2d3143907f4e329f929ce42ca0a5d 189 Pfam PF05233 PHB accumulation regulatory domain 76 114 9.4E-19 T 14-10-2018 IPR007897 PHB accumulation regulatory LH59_07070 48b2d3143907f4e329f929ce42ca0a5d 189 Pfam PF07879 PHB/PHA accumulation regulator DNA-binding domain 12 71 1.4E-30 T 14-10-2018 IPR012909 PHA accumulation regulator DNA-binding, N-terminal LH59_07070 48b2d3143907f4e329f929ce42ca0a5d 189 TIGRFAM TIGR01848 PHA_reg_PhaR: polyhydroxyalkanoate synthesis repressor PhaR 11 117 6.9E-46 T 14-10-2018 IPR010134 Polyhydroxyalkanoate synthesis repressor PhaR GO:0006355 LH59_21890 da46fd650a3773408c5340e29e0319eb 346 PIRSF PIRSF002756 5 339 2.9E-109 T 14-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 LH59_21890 da46fd650a3773408c5340e29e0319eb 346 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 27 334 1.2E-126 T 14-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 LH59_21890 da46fd650a3773408c5340e29e0319eb 346 Pfam PF12849 PBP superfamily domain 24 307 1.0E-60 T 14-10-2018 IPR024370 PBP domain LH59_21890 da46fd650a3773408c5340e29e0319eb 346 Gene3D G3DSA:3.40.190.10 28 324 1.6E-124 T 14-10-2018 LH59_21890 da46fd650a3773408c5340e29e0319eb 346 SUPERFAMILY SSF53850 27 337 5.03E-96 T 14-10-2018 LH59_21890 da46fd650a3773408c5340e29e0319eb 346 Gene3D G3DSA:3.40.190.10 101 277 1.6E-124 T 14-10-2018 LH59_02290 7c25145da71ad5b0db9e04ac80301a75 253 SUPERFAMILY SSF46785 23 92 1.01E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_02290 7c25145da71ad5b0db9e04ac80301a75 253 Pfam PF00392 Bacterial regulatory proteins, gntR family 26 88 1.1E-15 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_02290 7c25145da71ad5b0db9e04ac80301a75 253 Gene3D G3DSA:1.20.120.530 92 244 3.4E-23 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_02290 7c25145da71ad5b0db9e04ac80301a75 253 Gene3D G3DSA:1.10.10.10 22 89 1.5E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_02290 7c25145da71ad5b0db9e04ac80301a75 253 Pfam PF07729 FCD domain 100 233 4.2E-19 T 14-10-2018 IPR011711 GntR, C-terminal LH59_02290 7c25145da71ad5b0db9e04ac80301a75 253 SUPERFAMILY SSF48008 93 240 1.26E-16 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_02290 7c25145da71ad5b0db9e04ac80301a75 253 SMART SM00345 30 88 2.0E-7 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_02290 7c25145da71ad5b0db9e04ac80301a75 253 SMART SM00895 98 234 1.2E-7 T 14-10-2018 IPR011711 GntR, C-terminal LH59_13930 844b8bc4296011b6cedfdd5eda9046fb 506 SUPERFAMILY SSF51556 21 481 1.25E-37 T 14-10-2018 IPR032466 Metal-dependent hydrolase LH59_13930 844b8bc4296011b6cedfdd5eda9046fb 506 Pfam PF04909 Amidohydrolase 95 324 3.6E-13 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 LH59_14650 e97726464a3241a241e00e52121c3ec6 462 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 18 435 2.4E-37 T 14-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane LH59_10115 261398c0cc94183ec1ae86e22d1a1c22 246 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_10115 261398c0cc94183ec1ae86e22d1a1c22 246 Gene3D G3DSA:3.40.50.300 2 228 8.4E-61 T 14-10-2018 LH59_10115 261398c0cc94183ec1ae86e22d1a1c22 246 SUPERFAMILY SSF52540 5 237 6.25E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_10115 261398c0cc94183ec1ae86e22d1a1c22 246 Pfam PF00005 ABC transporter 23 160 8.8E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_10115 261398c0cc94183ec1ae86e22d1a1c22 246 SMART SM00382 31 225 2.9E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_26560 f97591a9e9b484c665569371af1ae142 374 Gene3D G3DSA:2.40.160.10 12 374 6.4E-82 T 14-10-2018 IPR023614 Porin domain superfamily LH59_26560 f97591a9e9b484c665569371af1ae142 374 PRINTS PR00184 Neisseria sp. porin signature 56 81 4.3E-10 T 14-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 LH59_26560 f97591a9e9b484c665569371af1ae142 374 PRINTS PR00184 Neisseria sp. porin signature 156 173 4.3E-10 T 14-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 LH59_26560 f97591a9e9b484c665569371af1ae142 374 PRINTS PR00184 Neisseria sp. porin signature 328 352 4.3E-10 T 14-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 LH59_26560 f97591a9e9b484c665569371af1ae142 374 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 54 65 3.4E-6 T 14-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 LH59_26560 f97591a9e9b484c665569371af1ae142 374 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 157 168 3.4E-6 T 14-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 LH59_26560 f97591a9e9b484c665569371af1ae142 374 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 331 348 3.4E-6 T 14-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 LH59_26560 f97591a9e9b484c665569371af1ae142 374 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 98 108 3.4E-6 T 14-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 LH59_26560 f97591a9e9b484c665569371af1ae142 374 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 199 211 3.4E-6 T 14-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 LH59_26560 f97591a9e9b484c665569371af1ae142 374 SUPERFAMILY SSF56935 22 374 8.24E-73 T 14-10-2018 LH59_26560 f97591a9e9b484c665569371af1ae142 374 Pfam PF13609 Gram-negative porin 7 354 6.0E-57 T 14-10-2018 LH59_02100 2883ada254852f6b5f95007789240be2 336 ProSitePatterns PS00211 ABC transporters family signature. 168 182 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_02100 2883ada254852f6b5f95007789240be2 336 SMART SM00382 53 245 2.6E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_02100 2883ada254852f6b5f95007789240be2 336 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 245 331 3.8E-29 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_02100 2883ada254852f6b5f95007789240be2 336 SUPERFAMILY SSF52540 9 267 2.61E-67 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_02100 2883ada254852f6b5f95007789240be2 336 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 247 311 3.3E-18 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_02100 2883ada254852f6b5f95007789240be2 336 Gene3D G3DSA:3.40.50.300 6 336 3.4E-97 T 14-10-2018 LH59_02100 2883ada254852f6b5f95007789240be2 336 Pfam PF00005 ABC transporter 45 196 3.5E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_02995 d7651012b7965cf0936faae4db21bb35 203 Gene3D G3DSA:3.40.50.850 3 202 7.6E-45 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 LH59_02995 d7651012b7965cf0936faae4db21bb35 203 SUPERFAMILY SSF52499 6 196 3.01E-43 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 LH59_02995 d7651012b7965cf0936faae4db21bb35 203 Pfam PF00857 Isochorismatase family 7 187 4.5E-35 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 LH59_24385 f2007ba22b5780d0dc0501c3ecefae09 188 SUPERFAMILY SSF142433 22 181 1.19E-50 T 14-10-2018 IPR036653 CinA-like, C-terminal LH59_24385 f2007ba22b5780d0dc0501c3ecefae09 188 Gene3D G3DSA:3.90.950.20 9 182 7.5E-55 T 14-10-2018 IPR036653 CinA-like, C-terminal LH59_24385 f2007ba22b5780d0dc0501c3ecefae09 188 Pfam PF02464 Competence-damaged protein 25 180 1.7E-53 T 14-10-2018 IPR008136 CinA, C-terminal LH59_24385 f2007ba22b5780d0dc0501c3ecefae09 188 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 30 177 6.3E-41 T 14-10-2018 IPR008136 CinA, C-terminal LH59_17770 f529b51f84fb9038b051bea8e01d021b 223 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 36 217 7.4E-24 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_17770 f529b51f84fb9038b051bea8e01d021b 223 TIGRFAM TIGR03003 ectoine_ehuD: ectoine/hydroxyectoine ABC transporter, permease protein EhuD 5 216 3.8E-92 T 14-10-2018 IPR014341 Ectoine/hydroxyectoine ABC transporter, permease protein EhuD LH59_17770 f529b51f84fb9038b051bea8e01d021b 223 SUPERFAMILY SSF161098 16 217 1.16E-41 T 14-10-2018 IPR035906 MetI-like superfamily LH59_17770 f529b51f84fb9038b051bea8e01d021b 223 Gene3D G3DSA:1.10.3720.10 4 219 1.6E-52 T 14-10-2018 IPR035906 MetI-like superfamily LH59_17770 f529b51f84fb9038b051bea8e01d021b 223 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 14 111 5.8E-26 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 LH59_11795 f576e472784d02e6e045c296a28685de 145 SUPERFAMILY SSF54637 13 138 2.19E-27 T 14-10-2018 IPR029069 HotDog domain superfamily LH59_11795 f576e472784d02e6e045c296a28685de 145 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 23 127 6.5E-16 T 14-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 LH59_11795 f576e472784d02e6e045c296a28685de 145 Pfam PF03061 Thioesterase superfamily 53 128 1.2E-13 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 LH59_11795 f576e472784d02e6e045c296a28685de 145 Gene3D G3DSA:3.10.129.10 7 142 4.7E-33 T 14-10-2018 LH59_03915 038ce521b87e62e46081229064ea121d 111 Gene3D G3DSA:1.10.760.10 27 107 2.6E-27 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_03915 038ce521b87e62e46081229064ea121d 111 PRINTS PR00606 Class ID cytochrome C signature 83 93 9.1E-14 T 14-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 LH59_03915 038ce521b87e62e46081229064ea121d 111 PRINTS PR00606 Class ID cytochrome C signature 95 105 9.1E-14 T 14-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 LH59_03915 038ce521b87e62e46081229064ea121d 111 PRINTS PR00606 Class ID cytochrome C signature 68 81 9.1E-14 T 14-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 LH59_03915 038ce521b87e62e46081229064ea121d 111 PRINTS PR00606 Class ID cytochrome C signature 29 42 9.1E-14 T 14-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 LH59_03915 038ce521b87e62e46081229064ea121d 111 SUPERFAMILY SSF46626 9 109 5.38E-16 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_03915 038ce521b87e62e46081229064ea121d 111 Pfam PF00034 Cytochrome c 26 106 4.4E-7 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_07950 1f1108160d1ed1f81b943ee361db5321 553 Gene3D G3DSA:1.20.1250.20 433 552 1.6E-9 T 14-10-2018 LH59_07950 1f1108160d1ed1f81b943ee361db5321 553 ProSitePatterns PS00217 Sugar transport proteins signature 2. 130 155 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 LH59_07950 1f1108160d1ed1f81b943ee361db5321 553 Gene3D G3DSA:1.20.1250.20 17 373 1.8E-56 T 14-10-2018 LH59_07950 1f1108160d1ed1f81b943ee361db5321 553 SUPERFAMILY SSF103473 13 548 1.48E-62 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_07950 1f1108160d1ed1f81b943ee361db5321 553 Pfam PF00083 Sugar (and other) transporter 22 236 3.5E-29 T 14-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 LH59_16490 519e18501885abccd99e5257ffa8c568 511 ProSitePatterns PS00216 Sugar transport proteins signature 1. 71 88 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 LH59_16490 519e18501885abccd99e5257ffa8c568 511 Pfam PF07690 Major Facilitator Superfamily 20 409 6.4E-43 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_16490 519e18501885abccd99e5257ffa8c568 511 Gene3D G3DSA:1.20.1250.20 270 505 7.5E-10 T 14-10-2018 LH59_16490 519e18501885abccd99e5257ffa8c568 511 Gene3D G3DSA:1.20.1720.10 17 255 1.2E-42 T 14-10-2018 LH59_16490 519e18501885abccd99e5257ffa8c568 511 SUPERFAMILY SSF103473 6 501 1.31E-54 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_13000 98a1e5cb5eb860e59ffb9a68c6e98864 302 Pfam PF00892 EamA-like transporter family 18 149 1.2E-14 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_13000 98a1e5cb5eb860e59ffb9a68c6e98864 302 Pfam PF00892 EamA-like transporter family 161 284 9.6E-9 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_13000 98a1e5cb5eb860e59ffb9a68c6e98864 302 SUPERFAMILY SSF103481 196 293 2.35E-14 T 14-10-2018 LH59_13000 98a1e5cb5eb860e59ffb9a68c6e98864 302 SUPERFAMILY SSF103481 52 153 5.62E-16 T 14-10-2018 LH59_15630 a72cc7332e1a60ffbc3eba4f40cb205c 308 Pfam PF03466 LysR substrate binding domain 88 294 4.6E-37 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_15630 a72cc7332e1a60ffbc3eba4f40cb205c 308 Gene3D G3DSA:1.10.10.10 1 88 7.5E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_15630 a72cc7332e1a60ffbc3eba4f40cb205c 308 SUPERFAMILY SSF46785 1 110 5.06E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_15630 a72cc7332e1a60ffbc3eba4f40cb205c 308 Gene3D G3DSA:3.40.190.290 90 294 3.5E-51 T 14-10-2018 LH59_15630 a72cc7332e1a60ffbc3eba4f40cb205c 308 SUPERFAMILY SSF53850 89 297 5.89E-39 T 14-10-2018 LH59_15630 a72cc7332e1a60ffbc3eba4f40cb205c 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 61 7.5E-15 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_25500 db93845efabe8fca796b4c888d03f85c 486 Pfam PF12679 ABC-2 family transporter protein 12 476 2.3E-23 T 14-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 LH59_05185 1a75ee843f3726b9eb2450493e39f584 251 PIRSF PIRSF037208 3 244 2.3E-88 T 14-10-2018 IPR017138 Aspartate/glutamate leucyltransferase GO:0008914|GO:0071596 MetaCyc: PWY-7802 LH59_05185 1a75ee843f3726b9eb2450493e39f584 251 SUPERFAMILY SSF55729 84 240 1.73E-20 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_05185 1a75ee843f3726b9eb2450493e39f584 251 Pfam PF04377 Arginine-tRNA-protein transferase, C terminus 110 231 5.4E-39 T 14-10-2018 IPR007472 N-end rule aminoacyl transferase, C-terminal GO:0004057|GO:0016598 MetaCyc: PWY-7802 LH59_05185 1a75ee843f3726b9eb2450493e39f584 251 Hamap MF_00689 Aspartate/glutamate leucyltransferase [bpt]. 10 237 40.902 T 14-10-2018 IPR017138 Aspartate/glutamate leucyltransferase GO:0008914|GO:0071596 MetaCyc: PWY-7802 LH59_05185 1a75ee843f3726b9eb2450493e39f584 251 Pfam PF04376 Arginine-tRNA-protein transferase, N terminus 20 90 1.6E-19 T 14-10-2018 IPR007471 N-end aminoacyl transferase, N-terminal GO:0004057|GO:0016598 MetaCyc: PWY-7802 LH59_17940 6444c45aaefb9cf8e6cf56877208129a 205 Pfam PF01618 MotA/TolQ/ExbB proton channel family 67 186 2.6E-28 T 14-10-2018 IPR002898 MotA/TolQ/ExbB proton channel LH59_20445 c082b90cf08d5585c205c90c347503aa 441 ProSitePatterns PS00217 Sugar transport proteins signature 2. 137 162 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 LH59_20445 c082b90cf08d5585c205c90c347503aa 441 Pfam PF07690 Major Facilitator Superfamily 65 397 1.2E-28 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_20445 c082b90cf08d5585c205c90c347503aa 441 SUPERFAMILY SSF103473 24 439 1.57E-61 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_20445 c082b90cf08d5585c205c90c347503aa 441 Gene3D G3DSA:1.20.1250.20 24 441 3.6E-65 T 14-10-2018 LH59_20090 6b1a1e5bef477e3dfadb78ec239d090d 522 Gene3D G3DSA:3.40.720.10 4 498 4.6E-148 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 LH59_20090 6b1a1e5bef477e3dfadb78ec239d090d 522 SUPERFAMILY SSF53649 6 492 7.33E-108 T 14-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 LH59_20090 6b1a1e5bef477e3dfadb78ec239d090d 522 Pfam PF00884 Sulfatase 5 382 8.9E-53 T 14-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 LH59_03095 47b3160bb0576bd2997eb3ddc3c77c7b 241 SMART SM00382 26 213 1.5E-19 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_03095 47b3160bb0576bd2997eb3ddc3c77c7b 241 Gene3D G3DSA:3.40.50.300 1 241 5.0E-78 T 14-10-2018 LH59_03095 47b3160bb0576bd2997eb3ddc3c77c7b 241 PIRSF PIRSF039085 1 241 6.2E-106 T 14-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 LH59_03095 47b3160bb0576bd2997eb3ddc3c77c7b 241 SUPERFAMILY SSF52540 1 235 1.65E-78 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_03095 47b3160bb0576bd2997eb3ddc3c77c7b 241 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_03095 47b3160bb0576bd2997eb3ddc3c77c7b 241 Pfam PF00005 ABC transporter 17 165 7.5E-35 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_06295 d2578098fc68c6dbbb229206b3094143 387 Pfam PF13458 Periplasmic binding protein 25 379 2.7E-49 T 14-10-2018 IPR028081 Leucine-binding protein domain LH59_06295 d2578098fc68c6dbbb229206b3094143 387 Gene3D G3DSA:3.40.50.2300 143 376 5.3E-116 T 14-10-2018 LH59_06295 d2578098fc68c6dbbb229206b3094143 387 Gene3D G3DSA:3.40.50.2300 28 367 5.3E-116 T 14-10-2018 LH59_06295 d2578098fc68c6dbbb229206b3094143 387 SUPERFAMILY SSF53822 26 383 2.62E-74 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_18700 f8e13e26b0a251ca8d476d1feedd8357 442 SUPERFAMILY SSF103473 2 434 2.62E-57 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_18700 f8e13e26b0a251ca8d476d1feedd8357 442 Gene3D G3DSA:1.20.1250.20 241 437 1.3E-18 T 14-10-2018 LH59_18700 f8e13e26b0a251ca8d476d1feedd8357 442 Gene3D G3DSA:1.20.1720.10 1 201 7.1E-38 T 14-10-2018 LH59_18700 f8e13e26b0a251ca8d476d1feedd8357 442 Pfam PF07690 Major Facilitator Superfamily 5 391 1.3E-42 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_10540 910ed376fe4618e5fb2acd5aeead5591 52 Pfam PF06796 Periplasmic nitrate reductase protein NapE 3 51 1.1E-22 T 14-10-2018 IPR010649 Nitrate/trimethylamine N-oxide reductase NapE/TorE LH59_10540 910ed376fe4618e5fb2acd5aeead5591 52 TIGRFAM TIGR02973 nitrate_rd_NapE: periplasmic nitrate reductase, NapE protein 10 51 4.7E-24 T 14-10-2018 IPR004448 Nitrate reductas, NapE, periplasmic LH59_25340 e59fc5d17d8fb6dd6684f445b77587a1 66 Pfam PF02597 ThiS family 3 66 8.0E-18 T 14-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 LH59_25340 e59fc5d17d8fb6dd6684f445b77587a1 66 SUPERFAMILY SSF54285 1 66 4.94E-20 T 14-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp LH59_25340 e59fc5d17d8fb6dd6684f445b77587a1 66 Gene3D G3DSA:3.10.20.30 1 66 5.4E-24 T 14-10-2018 IPR012675 Beta-grasp domain superfamily LH59_25340 e59fc5d17d8fb6dd6684f445b77587a1 66 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 66 4.1E-25 T 14-10-2018 IPR010035 ThiS, thiamine-biosynthesis LH59_28045 7161f00465ba09d42b5476f5ee99221b 461 SMART SM01230 120 376 1.3E-91 T 14-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 LH59_28045 7161f00465ba09d42b5476f5ee99221b 461 Pfam PF00120 Glutamine synthetase, catalytic domain 121 457 2.4E-96 T 14-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 LH59_28045 7161f00465ba09d42b5476f5ee99221b 461 SUPERFAMILY SSF55931 120 459 3.24E-104 T 14-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 LH59_28045 7161f00465ba09d42b5476f5ee99221b 461 Gene3D G3DSA:3.30.590.10 118 461 2.1E-106 T 14-10-2018 LH59_22695 e5c87e5f12eb76e0848a8e63dc9c8c07 212 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 207 1.9E-83 T 14-10-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 LH59_22695 e5c87e5f12eb76e0848a8e63dc9c8c07 212 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 2 208 42.571 T 14-10-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 LH59_22695 e5c87e5f12eb76e0848a8e63dc9c8c07 212 Pfam PF14681 Uracil phosphoribosyltransferase 7 207 1.6E-62 T 14-10-2018 LH59_22695 e5c87e5f12eb76e0848a8e63dc9c8c07 212 SUPERFAMILY SSF53271 3 206 7.74E-66 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like LH59_22695 e5c87e5f12eb76e0848a8e63dc9c8c07 212 Gene3D G3DSA:3.40.50.2020 2 208 1.3E-68 T 14-10-2018 LH59_14895 a6217d6b1dacec32975c1a360e07735e 309 SUPERFAMILY SSF53659 10 301 6.99E-64 T 14-10-2018 LH59_14895 a6217d6b1dacec32975c1a360e07735e 309 PIRSF PIRSF000428 2 304 1.4E-82 T 14-10-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 LH59_14895 a6217d6b1dacec32975c1a360e07735e 309 Pfam PF01515 Phosphate acetyl/butaryl transferase 84 298 3.1E-48 T 14-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 LH59_14895 a6217d6b1dacec32975c1a360e07735e 309 Gene3D G3DSA:3.40.718.10 10 302 3.1E-94 T 14-10-2018 LH59_08455 552326193037c8741aaf546dcafbdba3 314 Pfam PF03547 Membrane transport protein 4 146 7.9E-18 T 14-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 LH59_08455 552326193037c8741aaf546dcafbdba3 314 Pfam PF03547 Membrane transport protein 155 304 1.4E-17 T 14-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 LH59_15210 e900c01451ec5752aa0d1d0efe8fb2dc 168 Pfam PF04463 Protein of unknown function (DUF523) 4 150 5.6E-43 T 14-10-2018 IPR007553 Domain of unknown function DUF523 LH59_13805 f0c5ad71c40fc6c5457605c17ff4de59 166 SUPERFAMILY SSF52788 6 144 3.14E-40 T 14-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily LH59_13805 f0c5ad71c40fc6c5457605c17ff4de59 166 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 8 139 8.1E-17 T 14-10-2018 IPR023485 Phosphotyrosine protein phosphatase I LH59_13805 f0c5ad71c40fc6c5457605c17ff4de59 166 Gene3D G3DSA:3.40.50.2300 5 144 4.2E-41 T 14-10-2018 LH59_13805 f0c5ad71c40fc6c5457605c17ff4de59 166 SMART SM00226 6 144 2.9E-35 T 14-10-2018 IPR023485 Phosphotyrosine protein phosphatase I LH59_06330 9afc69f400922d907ab149ceaaa83578 336 Gene3D G3DSA:3.40.190.100 117 250 1.4E-44 T 14-10-2018 LH59_06330 9afc69f400922d907ab149ceaaa83578 336 Gene3D G3DSA:3.40.190.10 36 321 1.4E-44 T 14-10-2018 LH59_06330 9afc69f400922d907ab149ceaaa83578 336 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 35 311 3.7E-66 T 14-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 LH59_06330 9afc69f400922d907ab149ceaaa83578 336 SUPERFAMILY SSF53850 32 328 5.79E-77 T 14-10-2018 LH59_27125 f11236dd304a97917698e33a18a8c9ad 296 PIRSF PIRSF026649 1 296 2.9E-80 T 14-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 LH59_27125 f11236dd304a97917698e33a18a8c9ad 296 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 22 287 1.8E-66 T 14-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 LH59_06740 6531454d9ee753b848c12580b9683a7f 291 Pfam PF01418 Helix-turn-helix domain, rpiR family 8 78 2.3E-13 T 14-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 LH59_06740 6531454d9ee753b848c12580b9683a7f 291 SUPERFAMILY SSF53697 101 265 8.45E-24 T 14-10-2018 LH59_06740 6531454d9ee753b848c12580b9683a7f 291 Gene3D G3DSA:3.40.50.10490 99 281 2.7E-31 T 14-10-2018 LH59_06740 6531454d9ee753b848c12580b9683a7f 291 Pfam PF01380 SIS domain 135 243 1.5E-14 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 LH59_06740 6531454d9ee753b848c12580b9683a7f 291 SUPERFAMILY SSF46689 7 79 4.84E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_06740 6531454d9ee753b848c12580b9683a7f 291 Gene3D G3DSA:1.10.10.10 2 83 2.6E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_05490 2b8414fbdc1e1a89151a50c8a5333ff9 290 SUPERFAMILY SSF46689 5 77 2.69E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_05490 2b8414fbdc1e1a89151a50c8a5333ff9 290 Gene3D G3DSA:3.40.50.10490 97 277 1.4E-35 T 14-10-2018 LH59_05490 2b8414fbdc1e1a89151a50c8a5333ff9 290 Pfam PF01380 SIS domain 130 253 1.2E-16 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 LH59_05490 2b8414fbdc1e1a89151a50c8a5333ff9 290 Gene3D G3DSA:1.10.10.10 2 79 6.3E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_05490 2b8414fbdc1e1a89151a50c8a5333ff9 290 Pfam PF01418 Helix-turn-helix domain, rpiR family 9 77 3.4E-13 T 14-10-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 LH59_05490 2b8414fbdc1e1a89151a50c8a5333ff9 290 SUPERFAMILY SSF53697 99 280 1.1E-34 T 14-10-2018 LH59_16835 cd54bc36f769bcf7295caff194bdcf36 147 Pfam PF00011 Hsp20/alpha crystallin family 51 147 4.7E-19 T 14-10-2018 IPR002068 Alpha crystallin/Hsp20 domain LH59_16835 cd54bc36f769bcf7295caff194bdcf36 147 SUPERFAMILY SSF49764 24 146 4.36E-31 T 14-10-2018 IPR008978 HSP20-like chaperone LH59_16835 cd54bc36f769bcf7295caff194bdcf36 147 Gene3D G3DSA:2.60.40.790 6 147 1.6E-27 T 14-10-2018 IPR008978 HSP20-like chaperone LH59_20020 6bcfb825daf640c7b7a526a1e48c3494 424 Pfam PF13579 Glycosyl transferase 4-like domain 15 202 3.3E-29 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 LH59_20020 6bcfb825daf640c7b7a526a1e48c3494 424 Pfam PF13692 Glycosyl transferases group 1 228 366 2.1E-14 T 14-10-2018 LH59_20020 6bcfb825daf640c7b7a526a1e48c3494 424 Gene3D G3DSA:3.40.50.2000 1 209 8.2E-22 T 14-10-2018 LH59_20020 6bcfb825daf640c7b7a526a1e48c3494 424 Gene3D G3DSA:3.40.50.2000 210 383 4.1E-28 T 14-10-2018 LH59_20020 6bcfb825daf640c7b7a526a1e48c3494 424 SUPERFAMILY SSF53756 2 397 6.91E-52 T 14-10-2018 LH59_14540 06c930ea0e8c029ddd84032043a000b7 520 Gene3D G3DSA:1.10.3650.10 358 439 1.2E-27 T 14-10-2018 IPR038262 Nitrate reductase beta, C-terminal domain superfamily KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 LH59_14540 06c930ea0e8c029ddd84032043a000b7 520 Gene3D G3DSA:3.30.70.20 1 298 6.6E-102 T 14-10-2018 LH59_14540 06c930ea0e8c029ddd84032043a000b7 520 SUPERFAMILY SSF54862 1 499 8.58E-180 T 14-10-2018 LH59_14540 06c930ea0e8c029ddd84032043a000b7 520 TIGRFAM TIGR01660 narH: nitrate reductase, beta subunit 1 494 2.8E-286 T 14-10-2018 IPR006547 Nitrate reductase, beta subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 LH59_14540 06c930ea0e8c029ddd84032043a000b7 520 Pfam PF13247 4Fe-4S dicluster domain 175 271 3.2E-37 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain LH59_14540 06c930ea0e8c029ddd84032043a000b7 520 Pfam PF14711 Respiratory nitrate reductase beta C-terminal 358 441 3.5E-29 T 14-10-2018 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 LH59_24440 a0477e7c996f5c0f957a133fcf77179d 274 Gene3D G3DSA:1.10.3720.10 79 273 4.1E-28 T 14-10-2018 IPR035906 MetI-like superfamily LH59_24440 a0477e7c996f5c0f957a133fcf77179d 274 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 24 273 1.0E-88 T 14-10-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 LH59_24440 a0477e7c996f5c0f957a133fcf77179d 274 SUPERFAMILY SSF161098 77 264 1.7E-34 T 14-10-2018 IPR035906 MetI-like superfamily LH59_24440 a0477e7c996f5c0f957a133fcf77179d 274 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 266 2.8E-13 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_27485 e9f9d4d6e7c468e364e66c793e3c3525 403 SMART SM00155 306 332 0.024 T 14-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 LH59_27485 e9f9d4d6e7c468e364e66c793e3c3525 403 SMART SM00155 116 143 4.5E-4 T 14-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 LH59_27485 e9f9d4d6e7c468e364e66c793e3c3525 403 SUPERFAMILY SSF56024 9 192 6.54E-40 T 14-10-2018 LH59_27485 e9f9d4d6e7c468e364e66c793e3c3525 403 Pfam PF13091 PLD-like domain 237 357 2.2E-24 T 14-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 LH59_27485 e9f9d4d6e7c468e364e66c793e3c3525 403 Pfam PF13091 PLD-like domain 29 140 4.2E-16 T 14-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 LH59_27485 e9f9d4d6e7c468e364e66c793e3c3525 403 Gene3D G3DSA:3.30.870.10 8 203 2.1E-35 T 14-10-2018 LH59_27485 e9f9d4d6e7c468e364e66c793e3c3525 403 SUPERFAMILY SSF56024 190 377 4.26E-38 T 14-10-2018 LH59_27485 e9f9d4d6e7c468e364e66c793e3c3525 403 Gene3D G3DSA:3.30.870.10 218 362 1.2E-26 T 14-10-2018 LH59_27485 e9f9d4d6e7c468e364e66c793e3c3525 403 Hamap MF_01917 Cardiolipin synthase B [clsB]. 7 403 46.785 T 14-10-2018 IPR030872 Cardiolipin synthase B GO:0008808|GO:0032049 LH59_19960 b176c71dec966e676e88f85ccce118c3 143 Gene3D G3DSA:3.90.79.10 1 142 2.2E-31 T 14-10-2018 LH59_19960 b176c71dec966e676e88f85ccce118c3 143 Pfam PF00293 NUDIX domain 7 129 2.4E-13 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 LH59_19960 b176c71dec966e676e88f85ccce118c3 143 PIRSF PIRSF037599 1 142 2.0E-47 T 14-10-2018 IPR033715 GDP-mannose mannosyl hydrolase GO:0008727 LH59_19960 b176c71dec966e676e88f85ccce118c3 143 SUPERFAMILY SSF55811 4 134 2.44E-24 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 LH59_13710 f4585af94d43cfa2fb88bb472ef9e967 326 Gene3D G3DSA:3.40.190.150 30 316 5.6E-106 T 14-10-2018 LH59_13710 f4585af94d43cfa2fb88bb472ef9e967 326 SUPERFAMILY SSF53850 119 288 3.69E-13 T 14-10-2018 LH59_13710 f4585af94d43cfa2fb88bb472ef9e967 326 Gene3D G3DSA:3.40.190.10 127 251 5.6E-106 T 14-10-2018 LH59_13710 f4585af94d43cfa2fb88bb472ef9e967 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 321 1.5E-82 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_13710 f4585af94d43cfa2fb88bb472ef9e967 326 PIRSF PIRSF017082 1 326 1.7E-82 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_14885 20e81a33c3a2d2dc1caaf634e7349226 322 SUPERFAMILY SSF161098 92 306 8.5E-18 T 14-10-2018 IPR035906 MetI-like superfamily LH59_14885 20e81a33c3a2d2dc1caaf634e7349226 322 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 320 7.4E-43 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_14885 20e81a33c3a2d2dc1caaf634e7349226 322 Gene3D G3DSA:1.10.3720.10 87 316 1.3E-23 T 14-10-2018 IPR035906 MetI-like superfamily LH59_25925 bd4172f00803e77922080d53aa5f9647 446 Pfam PF02667 Short chain fatty acid transporter 2 437 8.7E-129 T 14-10-2018 IPR006160 Short chain fatty acid transporter AtoE LH59_04585 7bf0a6098015dfb49e5f0ab61161e3bf 318 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 9 312 29.553 T 14-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 LH59_04585 7bf0a6098015dfb49e5f0ab61161e3bf 318 Pfam PF01715 IPP transferase 43 291 3.4E-88 T 14-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 LH59_04585 7bf0a6098015dfb49e5f0ab61161e3bf 318 Gene3D G3DSA:1.10.20.140 116 187 9.1E-97 T 14-10-2018 LH59_04585 7bf0a6098015dfb49e5f0ab61161e3bf 318 Gene3D G3DSA:3.40.50.300 13 291 9.1E-97 T 14-10-2018 LH59_04585 7bf0a6098015dfb49e5f0ab61161e3bf 318 SUPERFAMILY SSF52540 10 152 6.06E-17 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_04585 7bf0a6098015dfb49e5f0ab61161e3bf 318 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 9 293 9.1E-92 T 14-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 LH59_21105 377f7a965c917c2c47d3a8dc93c46f7f 494 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 17 448 3.3E-118 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_21105 377f7a965c917c2c47d3a8dc93c46f7f 494 TIGRFAM TIGR00780 ccoN: cytochrome c oxidase, cbb3-type, subunit I 13 471 8.7E-231 T 14-10-2018 IPR004677 Cytochrome c oxidase cbb3-type, subunit I GO:0004129|GO:0045278|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 LH59_21105 377f7a965c917c2c47d3a8dc93c46f7f 494 SUPERFAMILY SSF81442 15 470 6.28E-127 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_21105 377f7a965c917c2c47d3a8dc93c46f7f 494 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 208 263 - T 14-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_21105 377f7a965c917c2c47d3a8dc93c46f7f 494 Gene3D G3DSA:1.20.210.10 7 473 8.8E-207 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_19810 37d12ccf3dd4d67fb46e7301c1d0d6bf 440 Pfam PF13629 Pilus formation protein N terminal region 21 95 4.2E-18 T 14-10-2018 IPR032789 Pilus formation protein, N-terminal LH59_19810 37d12ccf3dd4d67fb46e7301c1d0d6bf 440 Pfam PF00263 Bacterial type II and III secretion system protein 231 397 7.9E-44 T 14-10-2018 IPR004846 Type II/III secretion system GO:0009306 LH59_19810 37d12ccf3dd4d67fb46e7301c1d0d6bf 440 PRINTS PR00811 Bacterial general secretion pathway protein D signature 384 398 1.0E-14 T 14-10-2018 IPR001775 GspD/PilQ family LH59_19810 37d12ccf3dd4d67fb46e7301c1d0d6bf 440 PRINTS PR00811 Bacterial general secretion pathway protein D signature 160 170 1.0E-14 T 14-10-2018 IPR001775 GspD/PilQ family LH59_19810 37d12ccf3dd4d67fb46e7301c1d0d6bf 440 PRINTS PR00811 Bacterial general secretion pathway protein D signature 227 251 1.0E-14 T 14-10-2018 IPR001775 GspD/PilQ family LH59_19810 37d12ccf3dd4d67fb46e7301c1d0d6bf 440 PRINTS PR00811 Bacterial general secretion pathway protein D signature 264 274 1.0E-14 T 14-10-2018 IPR001775 GspD/PilQ family LH59_19810 37d12ccf3dd4d67fb46e7301c1d0d6bf 440 PRINTS PR00811 Bacterial general secretion pathway protein D signature 361 379 1.0E-14 T 14-10-2018 IPR001775 GspD/PilQ family LH59_09630 f2dc7e06929f846bf95dc9cf8da8fbeb 89 Pfam PF00381 PTS HPr component phosphorylation site 5 82 2.4E-27 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like LH59_09630 f2dc7e06929f846bf95dc9cf8da8fbeb 89 PRINTS PR00107 Phosphocarrier protein signature 13 29 2.4E-15 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like LH59_09630 f2dc7e06929f846bf95dc9cf8da8fbeb 89 PRINTS PR00107 Phosphocarrier protein signature 38 53 2.4E-15 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like LH59_09630 f2dc7e06929f846bf95dc9cf8da8fbeb 89 PRINTS PR00107 Phosphocarrier protein signature 53 70 2.4E-15 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like LH59_09630 f2dc7e06929f846bf95dc9cf8da8fbeb 89 Gene3D G3DSA:3.30.1340.10 1 88 1.2E-31 T 14-10-2018 IPR035895 HPr-like superfamily LH59_09630 f2dc7e06929f846bf95dc9cf8da8fbeb 89 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 14-10-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site LH59_09630 f2dc7e06929f846bf95dc9cf8da8fbeb 89 SUPERFAMILY SSF55594 1 87 4.84E-28 T 14-10-2018 IPR035895 HPr-like superfamily LH59_09630 f2dc7e06929f846bf95dc9cf8da8fbeb 89 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 14-10-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site LH59_09630 f2dc7e06929f846bf95dc9cf8da8fbeb 89 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 81 5.0E-29 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like LH59_02885 c3ec03e22caaee8846466fe2f0063bac 387 Gene3D G3DSA:3.40.50.2300 140 360 1.7E-91 T 14-10-2018 LH59_02885 c3ec03e22caaee8846466fe2f0063bac 387 Gene3D G3DSA:3.40.50.2300 23 350 1.7E-91 T 14-10-2018 LH59_02885 c3ec03e22caaee8846466fe2f0063bac 387 SUPERFAMILY SSF53822 22 385 1.7E-83 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_02885 c3ec03e22caaee8846466fe2f0063bac 387 Pfam PF13458 Periplasmic binding protein 22 358 3.5E-68 T 14-10-2018 IPR028081 Leucine-binding protein domain LH59_16745 dadfda46f061efa0ffb8abbdf0d1b3c1 259 SMART SM00345 28 87 4.9E-16 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_16745 dadfda46f061efa0ffb8abbdf0d1b3c1 259 SUPERFAMILY SSF46785 20 91 3.58E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_16745 dadfda46f061efa0ffb8abbdf0d1b3c1 259 SUPERFAMILY SSF64288 75 241 3.59E-7 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily LH59_16745 dadfda46f061efa0ffb8abbdf0d1b3c1 259 Pfam PF00392 Bacterial regulatory proteins, gntR family 24 87 2.5E-15 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_16745 dadfda46f061efa0ffb8abbdf0d1b3c1 259 Gene3D G3DSA:1.10.10.10 20 88 1.9E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_24490 6ac529aec7e6a88881d91e95475618cc 532 Gene3D G3DSA:1.20.1250.20 270 444 1.2E-22 T 14-10-2018 LH59_24490 6ac529aec7e6a88881d91e95475618cc 532 Gene3D G3DSA:1.20.1720.10 24 257 6.1E-46 T 14-10-2018 LH59_24490 6ac529aec7e6a88881d91e95475618cc 532 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 23 465 4.5E-71 T 14-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 LH59_24490 6ac529aec7e6a88881d91e95475618cc 532 Pfam PF07690 Major Facilitator Superfamily 29 421 5.4E-54 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_24490 6ac529aec7e6a88881d91e95475618cc 532 SUPERFAMILY SSF103473 25 431 2.22E-70 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_21255 9e5fbda04f61f9ef055810ef2c8a4607 252 PIRSF PIRSF004846 2 252 4.7E-76 T 14-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 LH59_21255 9e5fbda04f61f9ef055810ef2c8a4607 252 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 32 248 9.7E-59 T 14-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 LH59_21255 9e5fbda04f61f9ef055810ef2c8a4607 252 SUPERFAMILY SSF53850 26 251 2.96E-67 T 14-10-2018 LH59_21255 9e5fbda04f61f9ef055810ef2c8a4607 252 Gene3D G3DSA:3.40.190.10 29 249 4.1E-74 T 14-10-2018 LH59_21255 9e5fbda04f61f9ef055810ef2c8a4607 252 Pfam PF13531 Bacterial extracellular solute-binding protein 27 250 1.2E-51 T 14-10-2018 LH59_21255 9e5fbda04f61f9ef055810ef2c8a4607 252 Gene3D G3DSA:3.40.190.10 106 212 4.1E-74 T 14-10-2018 LH59_16015 c3e111c16387aac673f3e5bcdc7909b3 100 Gene3D G3DSA:1.10.10.10 1 99 9.1E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_16015 c3e111c16387aac673f3e5bcdc7909b3 100 SMART SM00418 5 98 2.0E-10 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LH59_16015 c3e111c16387aac673f3e5bcdc7909b3 100 Pfam PF12840 Helix-turn-helix domain 5 77 7.2E-12 T 14-10-2018 LH59_16015 c3e111c16387aac673f3e5bcdc7909b3 100 SUPERFAMILY SSF46785 2 96 3.98E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_24735 e0136ae6cd63286f4519c17a156a771a 146 SUPERFAMILY SSF82784 1 138 1.07E-36 T 14-10-2018 IPR036102 OsmC/Ohr superfamily LH59_24735 e0136ae6cd63286f4519c17a156a771a 146 Gene3D G3DSA:3.30.300.20 11 139 1.7E-32 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta LH59_24735 e0136ae6cd63286f4519c17a156a771a 146 Pfam PF02566 OsmC-like protein 35 132 2.9E-17 T 14-10-2018 IPR003718 OsmC/Ohr family LH59_18035 6baee4be18792d655618304509be8257 323 Gene3D G3DSA:3.40.190.150 27 313 2.0E-111 T 14-10-2018 LH59_18035 6baee4be18792d655618304509be8257 323 PIRSF PIRSF017082 1 322 3.7E-85 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_18035 6baee4be18792d655618304509be8257 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 319 5.9E-91 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_18035 6baee4be18792d655618304509be8257 323 SUPERFAMILY SSF53850 112 285 8.69E-14 T 14-10-2018 LH59_18035 6baee4be18792d655618304509be8257 323 Gene3D G3DSA:3.40.190.10 125 248 2.0E-111 T 14-10-2018 LH59_26680 ffa995f1b45d0f08d4fbc652632ef317 205 SUPERFAMILY SSF53155 19 96 2.16E-17 T 14-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 LH59_26680 ffa995f1b45d0f08d4fbc652632ef317 205 Gene3D G3DSA:1.10.10.10 91 176 1.0E-32 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_26680 ffa995f1b45d0f08d4fbc652632ef317 205 SUPERFAMILY SSF46767 91 172 1.83E-28 T 14-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 LH59_26680 ffa995f1b45d0f08d4fbc652632ef317 205 Gene3D G3DSA:3.30.160.70 18 88 8.4E-17 T 14-10-2018 LH59_26680 ffa995f1b45d0f08d4fbc652632ef317 205 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 92 171 9.4E-31 T 14-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 LH59_26680 ffa995f1b45d0f08d4fbc652632ef317 205 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 22 172 37.591 T 14-10-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 LH59_26680 ffa995f1b45d0f08d4fbc652632ef317 205 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 93 172 9.9E-30 T 14-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 LH59_26680 ffa995f1b45d0f08d4fbc652632ef317 205 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 142 148 - T 14-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 LH59_03015 c37de5a531fdfbd2e35b164fd1d1639b 425 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 4 424 1.9E-185 T 14-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 LH59_03015 c37de5a531fdfbd2e35b164fd1d1639b 425 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 3 425 104.225 T 14-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 LH59_03015 c37de5a531fdfbd2e35b164fd1d1639b 425 Gene3D G3DSA:3.90.1150.10 6 416 1.3E-174 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_03015 c37de5a531fdfbd2e35b164fd1d1639b 425 Pfam PF00202 Aminotransferase class-III 32 395 7.4E-77 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LH59_03015 c37de5a531fdfbd2e35b164fd1d1639b 425 SUPERFAMILY SSF53383 2 423 9.0E-132 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_03015 c37de5a531fdfbd2e35b164fd1d1639b 425 Gene3D G3DSA:3.40.640.10 69 317 1.3E-174 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_03015 c37de5a531fdfbd2e35b164fd1d1639b 425 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 234 270 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 LH59_12200 620ae2e6287a76f742659b6f79b2f59a 227 Pfam PF04367 Protein of unknown function (DUF502) 56 160 1.2E-23 T 14-10-2018 IPR007462 Protein of unknown function DUF502 LH59_16885 679ef5bb3c36ed44098e8c2ca7123154 339 SUPERFAMILY SSF53300 89 279 2.49E-35 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily LH59_16885 679ef5bb3c36ed44098e8c2ca7123154 339 SMART SM00327 91 275 2.0E-18 T 14-10-2018 IPR002035 von Willebrand factor, type A LH59_16885 679ef5bb3c36ed44098e8c2ca7123154 339 Pfam PF00092 von Willebrand factor type A domain 93 275 1.8E-22 T 14-10-2018 IPR002035 von Willebrand factor, type A LH59_16885 679ef5bb3c36ed44098e8c2ca7123154 339 Gene3D G3DSA:3.40.50.410 91 282 4.0E-52 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily LH59_07045 9e45cbd9bc3adb6cc27e279553a61751 262 Pfam PF13525 Outer membrane lipoprotein 30 235 1.7E-60 T 14-10-2018 IPR039565 Outer membrane lipoprotein BamD-like LH59_07045 9e45cbd9bc3adb6cc27e279553a61751 262 Hamap MF_00922 Outer membrane protein assembly factor BamD [bamD]. 1 241 37.693 T 14-10-2018 IPR017689 Outer membrane protein assembly factor BamD LH59_07045 9e45cbd9bc3adb6cc27e279553a61751 262 Gene3D G3DSA:1.25.40.10 30 251 1.4E-54 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_07045 9e45cbd9bc3adb6cc27e279553a61751 262 TIGRFAM TIGR03302 OM_YfiO: outer membrane assembly lipoprotein YfiO 2 246 5.3E-84 T 14-10-2018 IPR017689 Outer membrane protein assembly factor BamD LH59_07045 9e45cbd9bc3adb6cc27e279553a61751 262 SUPERFAMILY SSF48452 30 108 1.87E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_00705 c4b58a5608527aa6bc12f907c58e38b2 481 PRINTS PR00045 Sigma-54 factor signature 181 198 2.1E-27 T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 LH59_00705 c4b58a5608527aa6bc12f907c58e38b2 481 PRINTS PR00045 Sigma-54 factor signature 377 389 2.1E-27 T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 LH59_00705 c4b58a5608527aa6bc12f907c58e38b2 481 PRINTS PR00045 Sigma-54 factor signature 451 469 2.1E-27 T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 LH59_00705 c4b58a5608527aa6bc12f907c58e38b2 481 PRINTS PR00045 Sigma-54 factor signature 393 404 2.1E-27 T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 LH59_00705 c4b58a5608527aa6bc12f907c58e38b2 481 Pfam PF04963 Sigma-54 factor, core binding domain 108 305 1.4E-52 T 14-10-2018 IPR007046 RNA polymerase sigma factor 54, core-binding domain GO:0003677|GO:0006352 LH59_00705 c4b58a5608527aa6bc12f907c58e38b2 481 Gene3D G3DSA:1.10.10.60 418 475 1.8E-21 T 14-10-2018 LH59_00705 c4b58a5608527aa6bc12f907c58e38b2 481 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 456 463 - T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 LH59_00705 c4b58a5608527aa6bc12f907c58e38b2 481 PIRSF PIRSF000774 7 478 7.5E-148 T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 LH59_00705 c4b58a5608527aa6bc12f907c58e38b2 481 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 12 55 5.5E-16 T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 LH59_00705 c4b58a5608527aa6bc12f907c58e38b2 481 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 18 475 1.8E-132 T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 LH59_00705 c4b58a5608527aa6bc12f907c58e38b2 481 Pfam PF04552 Sigma-54, DNA binding domain 320 475 2.0E-62 T 14-10-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding LH59_00705 c4b58a5608527aa6bc12f907c58e38b2 481 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 365 384 - T 14-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 LH59_00705 c4b58a5608527aa6bc12f907c58e38b2 481 Gene3D G3DSA:1.10.10.1330 111 236 5.6E-18 T 14-10-2018 IPR038709 RNA polymerase sigma-54 factor, core-binding domain superfamily LH59_16005 6dbe602e0e7fc77cb9229a549e110180 159 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 18 152 8.8E-18 T 14-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like LH59_16005 6dbe602e0e7fc77cb9229a549e110180 159 Gene3D G3DSA:3.30.530.20 5 155 5.9E-33 T 14-10-2018 IPR023393 START-like domain superfamily LH59_16005 6dbe602e0e7fc77cb9229a549e110180 159 SUPERFAMILY SSF55961 9 153 2.65E-27 T 14-10-2018 LH59_10780 1274f48b080289a90ad4319887f7622c 178 SUPERFAMILY SSF117856 26 173 2.88E-22 T 14-10-2018 LH59_10780 1274f48b080289a90ad4319887f7622c 178 Gene3D G3DSA:3.30.1330.80 25 177 2.9E-14 T 14-10-2018 LH59_10780 1274f48b080289a90ad4319887f7622c 178 Pfam PF03479 Domain of unknown function (DUF296) 36 155 1.5E-5 T 14-10-2018 IPR005175 PPC domain LH59_12170 9f46a88fc7567423a92ba2363b759a66 148 Gene3D G3DSA:1.10.10.10 2 144 1.6E-36 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_12170 9f46a88fc7567423a92ba2363b759a66 148 SUPERFAMILY SSF46785 6 131 5.88E-28 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_12170 9f46a88fc7567423a92ba2363b759a66 148 Pfam PF02082 Transcriptional regulator 1 81 8.0E-22 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type LH59_00945 e7a98549f44907e62241220fd417112e 246 Gene3D G3DSA:3.20.20.70 1 242 2.9E-86 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_00945 e7a98549f44907e62241220fd417112e 246 SUPERFAMILY SSF51366 1 238 4.16E-74 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 LH59_00945 e7a98549f44907e62241220fd417112e 246 Pfam PF00977 Histidine biosynthesis protein 3 232 2.3E-78 T 14-10-2018 IPR006062 Histidine biosynthesis GO:0000105 LH59_00945 e7a98549f44907e62241220fd417112e 246 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 2 240 36.241 T 14-10-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 LH59_00945 e7a98549f44907e62241220fd417112e 246 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 3 236 1.7E-76 T 14-10-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 LH59_09445 e65b8b9ba3942711f1819ca5247a1ec5 273 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 3 240 6.9E-65 T 14-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 LH59_09445 e65b8b9ba3942711f1819ca5247a1ec5 273 SUPERFAMILY SSF55120 1 251 1.35E-86 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 LH59_09445 e65b8b9ba3942711f1819ca5247a1ec5 273 Gene3D G3DSA:3.30.70.580 1 107 2.5E-34 T 14-10-2018 LH59_09445 e65b8b9ba3942711f1819ca5247a1ec5 273 PIRSF PIRSF001430 1 260 1.3E-76 T 14-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 LH59_09445 e65b8b9ba3942711f1819ca5247a1ec5 273 Pfam PF01416 tRNA pseudouridine synthase 10 105 4.7E-8 T 14-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 LH59_09445 e65b8b9ba3942711f1819ca5247a1ec5 273 Pfam PF01416 tRNA pseudouridine synthase 145 247 1.2E-29 T 14-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 LH59_09445 e65b8b9ba3942711f1819ca5247a1ec5 273 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 246 33.313 T 14-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 LH59_09445 e65b8b9ba3942711f1819ca5247a1ec5 273 Gene3D G3DSA:3.30.70.660 108 245 6.3E-47 T 14-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 LH59_18895 8dc785392381dd1d6001914d1dde286b 160 Pfam PF09722 Protein of unknown function (DUF2384) 108 157 1.3E-9 T 14-10-2018 IPR024467 Domain of unknown function DUF2384 LH59_14305 e4f5799e6edff1dd3a940463540d1835 295 PRINTS PR00111 Alpha/beta hydrolase fold signature 63 78 2.8E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_14305 e4f5799e6edff1dd3a940463540d1835 295 PRINTS PR00111 Alpha/beta hydrolase fold signature 121 134 2.8E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_14305 e4f5799e6edff1dd3a940463540d1835 295 PRINTS PR00111 Alpha/beta hydrolase fold signature 107 120 2.8E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_14305 e4f5799e6edff1dd3a940463540d1835 295 Pfam PF12697 Alpha/beta hydrolase family 40 288 5.3E-18 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_14305 e4f5799e6edff1dd3a940463540d1835 295 PRINTS PR00412 Epoxide hydrolase signature 107 120 1.7E-9 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 LH59_14305 e4f5799e6edff1dd3a940463540d1835 295 PRINTS PR00412 Epoxide hydrolase signature 271 293 1.7E-9 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 LH59_14305 e4f5799e6edff1dd3a940463540d1835 295 PRINTS PR00412 Epoxide hydrolase signature 44 62 1.7E-9 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 LH59_14305 e4f5799e6edff1dd3a940463540d1835 295 SUPERFAMILY SSF53474 16 295 1.53E-65 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_14305 e4f5799e6edff1dd3a940463540d1835 295 Gene3D G3DSA:3.40.50.1820 16 295 6.3E-86 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_22435 0fadd78524382530ded84cd115b66c78 323 PIRSF PIRSF017082 1 323 3.0E-88 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_22435 0fadd78524382530ded84cd115b66c78 323 Gene3D G3DSA:3.40.190.150 28 313 1.4E-111 T 14-10-2018 LH59_22435 0fadd78524382530ded84cd115b66c78 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 320 6.9E-85 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_22435 0fadd78524382530ded84cd115b66c78 323 SUPERFAMILY SSF53850 114 282 2.57E-8 T 14-10-2018 LH59_22435 0fadd78524382530ded84cd115b66c78 323 Gene3D G3DSA:3.40.190.10 126 248 1.4E-111 T 14-10-2018 LH59_25320 5dc2f51ea45c0a6b46198cf62c9bda5d 397 Pfam PF02515 CoA-transferase family III 6 373 1.1E-122 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 LH59_25320 5dc2f51ea45c0a6b46198cf62c9bda5d 397 SUPERFAMILY SSF89796 5 396 1.14E-128 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily LH59_25320 5dc2f51ea45c0a6b46198cf62c9bda5d 397 Gene3D G3DSA:3.40.50.10540 6 390 5.0E-129 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily LH59_25320 5dc2f51ea45c0a6b46198cf62c9bda5d 397 Gene3D G3DSA:3.30.1540.10 228 325 5.0E-129 T 14-10-2018 LH59_22430 f0d6e7ed5485d2892b6c978f40a6ca26 610 SUPERFAMILY SSF56235 3 609 3.09E-133 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal LH59_22430 f0d6e7ed5485d2892b6c978f40a6ca26 610 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 108 126 4.0E-21 T 14-10-2018 LH59_22430 f0d6e7ed5485d2892b6c978f40a6ca26 610 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 495 512 4.0E-21 T 14-10-2018 LH59_22430 f0d6e7ed5485d2892b6c978f40a6ca26 610 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 126 145 4.0E-21 T 14-10-2018 LH59_22430 f0d6e7ed5485d2892b6c978f40a6ca26 610 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 471 486 4.0E-21 T 14-10-2018 LH59_22430 f0d6e7ed5485d2892b6c978f40a6ca26 610 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 37 62 4.0E-21 T 14-10-2018 LH59_22430 f0d6e7ed5485d2892b6c978f40a6ca26 610 Gene3D G3DSA:3.60.20.40 417 609 9.4E-44 T 14-10-2018 LH59_22430 f0d6e7ed5485d2892b6c978f40a6ca26 610 Gene3D G3DSA:1.10.246.130 265 380 4.8E-30 T 14-10-2018 LH59_22430 f0d6e7ed5485d2892b6c978f40a6ca26 610 Pfam PF01019 Gamma-glutamyltranspeptidase 31 602 3.7E-119 T 14-10-2018 LH59_17345 565f6b7912102b5cb7033dc8fe90677d 236 Hamap MF_01146 Aquaporin Z [aqpZ]. 5 233 35.022 T 14-10-2018 IPR023743 Aquaporin Z GO:0006833|GO:0015250|GO:0016021|GO:0055085 LH59_17345 565f6b7912102b5cb7033dc8fe90677d 236 Pfam PF00230 Major intrinsic protein 5 226 1.8E-50 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 LH59_17345 565f6b7912102b5cb7033dc8fe90677d 236 PRINTS PR00783 Major intrinsic protein family signature 170 192 2.1E-52 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 LH59_17345 565f6b7912102b5cb7033dc8fe90677d 236 PRINTS PR00783 Major intrinsic protein family signature 6 25 2.1E-52 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 LH59_17345 565f6b7912102b5cb7033dc8fe90677d 236 PRINTS PR00783 Major intrinsic protein family signature 83 102 2.1E-52 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 LH59_17345 565f6b7912102b5cb7033dc8fe90677d 236 PRINTS PR00783 Major intrinsic protein family signature 46 70 2.1E-52 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 LH59_17345 565f6b7912102b5cb7033dc8fe90677d 236 PRINTS PR00783 Major intrinsic protein family signature 140 158 2.1E-52 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 LH59_17345 565f6b7912102b5cb7033dc8fe90677d 236 PRINTS PR00783 Major intrinsic protein family signature 209 229 2.1E-52 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 LH59_17345 565f6b7912102b5cb7033dc8fe90677d 236 Gene3D G3DSA:1.20.1080.10 3 233 3.2E-86 T 14-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 LH59_17345 565f6b7912102b5cb7033dc8fe90677d 236 ProSitePatterns PS00221 MIP family signature. 64 72 - T 14-10-2018 IPR022357 Major intrinsic protein, conserved site Reactome: R-HSA-432047 LH59_17345 565f6b7912102b5cb7033dc8fe90677d 236 SUPERFAMILY SSF81338 6 229 7.33E-67 T 14-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 LH59_17345 565f6b7912102b5cb7033dc8fe90677d 236 TIGRFAM TIGR00861 MIP: MIP family channel proteins 10 226 2.3E-60 T 14-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 LH59_25700 772de47510075bd54d64a5cb9f39a949 286 Gene3D G3DSA:1.10.10.10 113 223 2.0E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_25700 772de47510075bd54d64a5cb9f39a949 286 Pfam PF03551 Transcriptional regulator PadR-like family 129 197 2.2E-17 T 14-10-2018 IPR005149 Transcription regulator PadR, N-terminal LH59_25700 772de47510075bd54d64a5cb9f39a949 286 SUPERFAMILY SSF46785 124 274 2.82E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_20525 4d216e4801205d3c3853a058673d51c1 337 TIGRFAM TIGR02817 adh_fam_1: zinc-binding alcohol dehydrogenase family protein 2 337 7.9E-166 T 14-10-2018 IPR014182 Alcohol dehydrogenase, zinc-binding type 1 GO:0008270 LH59_20525 4d216e4801205d3c3853a058673d51c1 337 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 90 6.1E-7 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 LH59_20525 4d216e4801205d3c3853a058673d51c1 337 Gene3D G3DSA:3.90.180.10 23 334 3.3E-103 T 14-10-2018 LH59_20525 4d216e4801205d3c3853a058673d51c1 337 SUPERFAMILY SSF51735 117 286 5.77E-33 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_20525 4d216e4801205d3c3853a058673d51c1 337 SUPERFAMILY SSF50129 13 144 7.76E-33 T 14-10-2018 IPR011032 GroES-like superfamily LH59_20525 4d216e4801205d3c3853a058673d51c1 337 Pfam PF13602 Zinc-binding dehydrogenase 194 334 3.4E-20 T 14-10-2018 LH59_20525 4d216e4801205d3c3853a058673d51c1 337 Gene3D G3DSA:3.40.50.720 128 273 3.3E-103 T 14-10-2018 LH59_20525 4d216e4801205d3c3853a058673d51c1 337 SMART SM00829 13 334 3.2E-11 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 LH59_13470 2986f4aa066e602bf9539bb97f3ea027 587 SMART SM00267 410 584 8.0E-47 T 14-10-2018 IPR000160 GGDEF domain LH59_13470 2986f4aa066e602bf9539bb97f3ea027 587 Pfam PF00990 Diguanylate cyclase, GGDEF domain 421 580 3.1E-42 T 14-10-2018 IPR000160 GGDEF domain LH59_13470 2986f4aa066e602bf9539bb97f3ea027 587 Gene3D G3DSA:3.30.70.270 411 583 4.8E-52 T 14-10-2018 LH59_13470 2986f4aa066e602bf9539bb97f3ea027 587 Gene3D G3DSA:1.20.1480.50 310 410 4.0E-5 T 14-10-2018 LH59_13470 2986f4aa066e602bf9539bb97f3ea027 587 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 417 582 4.2E-45 T 14-10-2018 IPR000160 GGDEF domain LH59_13470 2986f4aa066e602bf9539bb97f3ea027 587 SUPERFAMILY SSF55073 426 582 1.02E-44 T 14-10-2018 IPR029787 Nucleotide cyclase LH59_12225 d08d626bbd912b4a461b1b762fff9692 290 SUPERFAMILY SSF103481 45 141 1.7E-8 T 14-10-2018 LH59_12225 d08d626bbd912b4a461b1b762fff9692 290 Pfam PF00892 EamA-like transporter family 16 138 1.5E-7 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_12225 d08d626bbd912b4a461b1b762fff9692 290 Pfam PF00892 EamA-like transporter family 151 281 8.5E-12 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_12225 d08d626bbd912b4a461b1b762fff9692 290 SUPERFAMILY SSF103481 185 284 8.37E-12 T 14-10-2018 LH59_21275 e54ab779d6599c8ecf30d43d2d4df5dc 345 Pfam PF13421 SPFH domain-Band 7 family 26 235 1.4E-73 T 14-10-2018 IPR033880 SPFH domain, YdjI-like LH59_21275 e54ab779d6599c8ecf30d43d2d4df5dc 345 Pfam PF09851 Short C-terminal domain 313 340 3.6E-7 T 14-10-2018 IPR018649 SHOCT domain LH59_21275 e54ab779d6599c8ecf30d43d2d4df5dc 345 Gene3D G3DSA:3.30.479.30 112 233 7.0E-8 T 14-10-2018 LH59_21275 e54ab779d6599c8ecf30d43d2d4df5dc 345 SUPERFAMILY SSF117892 124 231 2.88E-12 T 14-10-2018 IPR036013 Band 7/SPFH domain superfamily LH59_04570 e1ff30727e47536172b9020a8d1675f3 233 TIGRFAM TIGR03420 DnaA_homol_Hda: DnaA regulatory inactivator Hda 4 226 9.9E-68 T 14-10-2018 IPR017788 DnaA regulatory inactivator Hda GO:0032297 LH59_04570 e1ff30727e47536172b9020a8d1675f3 233 Gene3D G3DSA:1.10.8.60 161 226 3.2E-23 T 14-10-2018 LH59_04570 e1ff30727e47536172b9020a8d1675f3 233 SUPERFAMILY SSF52540 33 206 3.01E-16 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_04570 e1ff30727e47536172b9020a8d1675f3 233 Gene3D G3DSA:3.40.50.300 28 158 9.0E-19 T 14-10-2018 LH59_04570 e1ff30727e47536172b9020a8d1675f3 233 Pfam PF00308 Bacterial dnaA protein 17 206 4.3E-11 T 14-10-2018 IPR013317 Chromosomal replication initiator protein DnaA LH59_04750 2361779f6cffdbc2d20968e086cbda77 157 Gene3D G3DSA:3.10.450.50 5 157 1.3E-36 T 14-10-2018 LH59_04750 2361779f6cffdbc2d20968e086cbda77 157 SUPERFAMILY SSF54427 2 157 1.79E-45 T 14-10-2018 IPR032710 NTF2-like domain superfamily LH59_04750 2361779f6cffdbc2d20968e086cbda77 157 Pfam PF00866 Ring hydroxylating beta subunit 18 150 9.7E-11 T 14-10-2018 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0006725|GO:0055114 LH59_26015 46f4bc67481d9dd42a9f2d1eb46bef94 235 Pfam PF00005 ABC transporter 17 162 2.3E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_26015 46f4bc67481d9dd42a9f2d1eb46bef94 235 PIRSF PIRSF039137 1 235 3.3E-103 T 14-10-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 LH59_26015 46f4bc67481d9dd42a9f2d1eb46bef94 235 SUPERFAMILY SSF52540 2 232 9.71E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_26015 46f4bc67481d9dd42a9f2d1eb46bef94 235 Gene3D G3DSA:3.40.50.300 1 235 4.6E-63 T 14-10-2018 LH59_26015 46f4bc67481d9dd42a9f2d1eb46bef94 235 SMART SM00382 26 214 4.1E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_03035 ae75901fc7b4549e3842447c8f5d9b3b 195 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 14 195 37.409 T 14-10-2018 IPR003774 Protein of unknown function UPF0301 LH59_03035 ae75901fc7b4549e3842447c8f5d9b3b 195 SUPERFAMILY SSF143456 15 195 1.44E-59 T 14-10-2018 LH59_03035 ae75901fc7b4549e3842447c8f5d9b3b 195 Pfam PF02622 Uncharacterized ACR, COG1678 25 182 1.6E-44 T 14-10-2018 IPR003774 Protein of unknown function UPF0301 LH59_03035 ae75901fc7b4549e3842447c8f5d9b3b 195 Gene3D G3DSA:3.40.1740.10 9 195 6.4E-64 T 14-10-2018 LH59_01055 13fd8e1402ce588761446a133c45ef26 80 Pfam PF00364 Biotin-requiring enzyme 5 78 1.3E-18 T 14-10-2018 IPR000089 Biotin/lipoyl attachment LH59_01055 13fd8e1402ce588761446a133c45ef26 80 Gene3D G3DSA:2.40.50.100 1 79 4.3E-27 T 14-10-2018 LH59_01055 13fd8e1402ce588761446a133c45ef26 80 SUPERFAMILY SSF51230 4 79 4.71E-22 T 14-10-2018 IPR011053 Single hybrid motif LH59_01055 13fd8e1402ce588761446a133c45ef26 80 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 40 53 1.7E-13 T 14-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 LH59_01055 13fd8e1402ce588761446a133c45ef26 80 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 8 21 1.7E-13 T 14-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 LH59_01055 13fd8e1402ce588761446a133c45ef26 80 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 25 39 1.7E-13 T 14-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 LH59_11620 35769690ff97d4900bbfacc2bc18bbdc 170 Gene3D G3DSA:3.30.2010.10 75 164 5.2E-6 T 14-10-2018 LH59_11620 35769690ff97d4900bbfacc2bc18bbdc 170 Pfam PF01863 Protein of unknown function DUF45 97 156 2.6E-10 T 14-10-2018 IPR002725 Protein of unknown function DUF45 LH59_23670 a1168f6900986b015d1b99e4f61af3b6 330 PIRSF PIRSF018266 5 329 2.2E-83 T 14-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component LH59_23670 a1168f6900986b015d1b99e4f61af3b6 330 Pfam PF16220 Domain of unknown function (DUF4880) 17 57 2.8E-7 T 14-10-2018 IPR032623 FecR, N-terminal LH59_23670 a1168f6900986b015d1b99e4f61af3b6 330 Gene3D G3DSA:2.60.120.1440 111 247 1.4E-23 T 14-10-2018 LH59_23670 a1168f6900986b015d1b99e4f61af3b6 330 Pfam PF16344 Domain of unknown function (DUF4974) 244 312 1.9E-7 T 14-10-2018 IPR032508 Protein FecR, C-terminal LH59_23670 a1168f6900986b015d1b99e4f61af3b6 330 Pfam PF04773 FecR protein 121 212 7.3E-22 T 14-10-2018 IPR006860 FecR protein LH59_01175 0e70a192c5940daf0e12012bb5361251 201 Gene3D G3DSA:3.40.30.10 39 198 1.4E-54 T 14-10-2018 LH59_01175 0e70a192c5940daf0e12012bb5361251 201 Pfam PF02630 SCO1/SenC 41 177 1.1E-45 T 14-10-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_01175 0e70a192c5940daf0e12012bb5361251 201 SUPERFAMILY SSF52833 45 200 4.76E-52 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_21170 b020a8d2c9f8b5bc71864ef3c0f52a5a 302 SUPERFAMILY SSF53850 92 299 4.52E-41 T 14-10-2018 LH59_21170 b020a8d2c9f8b5bc71864ef3c0f52a5a 302 Gene3D G3DSA:1.10.10.10 7 93 3.8E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_21170 b020a8d2c9f8b5bc71864ef3c0f52a5a 302 Gene3D G3DSA:3.40.190.10 166 267 7.7E-61 T 14-10-2018 LH59_21170 b020a8d2c9f8b5bc71864ef3c0f52a5a 302 Pfam PF03466 LysR substrate binding domain 91 295 6.0E-39 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_21170 b020a8d2c9f8b5bc71864ef3c0f52a5a 302 Gene3D G3DSA:3.40.190.10 94 291 7.7E-61 T 14-10-2018 LH59_21170 b020a8d2c9f8b5bc71864ef3c0f52a5a 302 SUPERFAMILY SSF46785 8 114 5.1E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_21170 b020a8d2c9f8b5bc71864ef3c0f52a5a 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 66 1.6E-19 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_02680 a9c28bbd47e3dcbad09bbde8b25e2dbe 251 SUPERFAMILY SSF52540 7 248 1.85E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_02680 a9c28bbd47e3dcbad09bbde8b25e2dbe 251 SMART SM00382 31 225 1.8E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_02680 a9c28bbd47e3dcbad09bbde8b25e2dbe 251 Gene3D G3DSA:3.40.50.300 5 251 1.4E-56 T 14-10-2018 LH59_02680 a9c28bbd47e3dcbad09bbde8b25e2dbe 251 Pfam PF00005 ABC transporter 23 178 2.4E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_02680 a9c28bbd47e3dcbad09bbde8b25e2dbe 251 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 225 247 8.2E-8 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal LH59_18070 1bf644fe4445e47081ce0abe11e92c34 148 SMART SM00347 27 127 7.5E-21 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_18070 1bf644fe4445e47081ce0abe11e92c34 148 Gene3D G3DSA:1.10.10.10 4 140 3.7E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_18070 1bf644fe4445e47081ce0abe11e92c34 148 SUPERFAMILY SSF46785 6 142 1.16E-28 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_18070 1bf644fe4445e47081ce0abe11e92c34 148 TIGRFAM TIGR02337 HpaR: homoprotocatechuate degradation operon regulator, HpaR 9 132 1.2E-48 T 14-10-2018 IPR012712 Homoprotocatechuate degradation transcriptional regulator HpaR GO:0003677|GO:0010124|GO:0045892 LH59_18070 1bf644fe4445e47081ce0abe11e92c34 148 Pfam PF01047 MarR family 35 90 1.0E-13 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_18070 1bf644fe4445e47081ce0abe11e92c34 148 ProSitePatterns PS01117 MarR-type HTH domain signature. 66 100 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site LH59_18070 1bf644fe4445e47081ce0abe11e92c34 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 51 67 6.6E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_18070 1bf644fe4445e47081ce0abe11e92c34 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 6.6E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_18070 1bf644fe4445e47081ce0abe11e92c34 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 6.6E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_24885 cb157bde95d24db258a6f10e16ac7fdb 630 Pfam PF01103 Surface antigen 442 630 1.5E-23 T 14-10-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 LH59_24885 cb157bde95d24db258a6f10e16ac7fdb 630 Gene3D G3DSA:2.40.160.50 319 629 4.8E-50 T 14-10-2018 LH59_24885 cb157bde95d24db258a6f10e16ac7fdb 630 Gene3D G3DSA:3.10.20.310 198 266 5.1E-8 T 14-10-2018 LH59_24885 cb157bde95d24db258a6f10e16ac7fdb 630 Pfam PF17243 POTRA domain TamA domain 1 32 94 3.2E-7 T 14-10-2018 IPR035243 TamA, POTRA domain 1 LH59_26895 cedab8735903fc3348c7d0d2ab6d3d1d 412 Gene3D G3DSA:3.50.50.60 125 266 8.6E-86 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_26895 cedab8735903fc3348c7d0d2ab6d3d1d 412 SUPERFAMILY SSF51905 10 154 2.03E-25 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_26895 cedab8735903fc3348c7d0d2ab6d3d1d 412 Gene3D G3DSA:3.50.50.60 13 331 8.6E-86 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_26895 cedab8735903fc3348c7d0d2ab6d3d1d 412 SUPERFAMILY SSF51905 123 266 1.2E-21 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_04010 1089bd81103d24b940eda2165af29133 365 PIRSF PIRSF004486 1 330 2.8E-94 T 14-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 LH59_04010 1089bd81103d24b940eda2165af29133 365 SUPERFAMILY SSF81799 135 234 2.88E-33 T 14-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 LH59_04010 1089bd81103d24b940eda2165af29133 365 Gene3D G3DSA:1.10.150.170 133 235 2.6E-96 T 14-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 LH59_04010 1089bd81103d24b940eda2165af29133 365 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 5 329 36.322 T 14-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 LH59_04010 1089bd81103d24b940eda2165af29133 365 Pfam PF01795 MraW methylase family 2 328 8.4E-100 T 14-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 LH59_04010 1089bd81103d24b940eda2165af29133 365 Gene3D G3DSA:3.40.50.150 42 328 2.6E-96 T 14-10-2018 LH59_04010 1089bd81103d24b940eda2165af29133 365 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 43 328 7.6E-98 T 14-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 LH59_04010 1089bd81103d24b940eda2165af29133 365 SUPERFAMILY SSF53335 5 328 6.92E-39 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_22305 66d02ee1b5dca1260d9a17d2bd5fdd78 213 Pfam PF01144 Coenzyme A transferase 8 201 2.4E-38 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 LH59_22305 66d02ee1b5dca1260d9a17d2bd5fdd78 213 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 46 54 - T 14-10-2018 IPR004164 Coenzyme A transferase active site GO:0008410 Reactome: R-HSA-77108 LH59_22305 66d02ee1b5dca1260d9a17d2bd5fdd78 213 SUPERFAMILY SSF100950 6 211 1.77E-62 T 14-10-2018 IPR037171 NagB/RpiA transferase-like LH59_22305 66d02ee1b5dca1260d9a17d2bd5fdd78 213 SMART SM00882 8 205 6.6E-68 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 LH59_22305 66d02ee1b5dca1260d9a17d2bd5fdd78 213 Gene3D G3DSA:3.40.1080.10 2 212 1.3E-84 T 14-10-2018 LH59_22305 66d02ee1b5dca1260d9a17d2bd5fdd78 213 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 6 210 9.2E-88 T 14-10-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 LH59_23285 b3944990bf368b3158d4c7a1c1f53217 253 Pfam PF00005 ABC transporter 17 171 5.7E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_23285 b3944990bf368b3158d4c7a1c1f53217 253 Gene3D G3DSA:3.40.50.300 1 252 9.0E-69 T 14-10-2018 LH59_23285 b3944990bf368b3158d4c7a1c1f53217 253 SMART SM00382 26 219 4.4E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_23285 b3944990bf368b3158d4c7a1c1f53217 253 SUPERFAMILY SSF52540 1 241 6.17E-70 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_23285 b3944990bf368b3158d4c7a1c1f53217 253 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_23285 b3944990bf368b3158d4c7a1c1f53217 253 PIRSF PIRSF039085 1 247 3.9E-94 T 14-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 LH59_24000 8b6a6a73e5f97e0fc8508d09cc25a478 291 Gene3D G3DSA:3.90.550.10 64 142 1.5E-5 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases LH59_24000 8b6a6a73e5f97e0fc8508d09cc25a478 291 SUPERFAMILY SSF53448 1 215 1.49E-14 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases LH59_25510 195bb2de0a8fc722836706a2edd46231 399 Gene3D G3DSA:1.20.1250.20 13 386 4.9E-43 T 14-10-2018 LH59_25510 195bb2de0a8fc722836706a2edd46231 399 Pfam PF07690 Major Facilitator Superfamily 19 350 1.2E-32 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_25510 195bb2de0a8fc722836706a2edd46231 399 SUPERFAMILY SSF103473 10 390 8.63E-55 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_09550 6b6f311f3d08f659ecced63edad6a254 279 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 2 50 4.0E-7 T 14-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain LH59_09550 6b6f311f3d08f659ecced63edad6a254 279 SUPERFAMILY SSF161098 70 256 1.7E-28 T 14-10-2018 IPR035906 MetI-like superfamily LH59_09550 6b6f311f3d08f659ecced63edad6a254 279 Gene3D G3DSA:1.10.3720.10 66 277 7.5E-20 T 14-10-2018 IPR035906 MetI-like superfamily LH59_09550 6b6f311f3d08f659ecced63edad6a254 279 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 276 6.7E-26 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_27810 9c3334efd478fc44e03daaf6d6654b89 475 Pfam PF00171 Aldehyde dehydrogenase family 14 471 1.6E-157 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 LH59_27810 9c3334efd478fc44e03daaf6d6654b89 475 Gene3D G3DSA:3.40.309.10 253 442 1.3E-165 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 LH59_27810 9c3334efd478fc44e03daaf6d6654b89 475 SUPERFAMILY SSF53720 3 473 1.83E-162 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 LH59_27810 9c3334efd478fc44e03daaf6d6654b89 475 Gene3D G3DSA:3.40.605.10 9 470 1.3E-165 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 LH59_12775 47cfa5ee21060130ed36818b3c5bfe42 258 SUPERFAMILY SSF52540 4 243 6.75E-79 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_12775 47cfa5ee21060130ed36818b3c5bfe42 258 Gene3D G3DSA:3.40.50.300 2 256 1.4E-74 T 14-10-2018 LH59_12775 47cfa5ee21060130ed36818b3c5bfe42 258 SMART SM00382 33 218 2.1E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_12775 47cfa5ee21060130ed36818b3c5bfe42 258 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_12775 47cfa5ee21060130ed36818b3c5bfe42 258 Pfam PF00005 ABC transporter 25 168 5.4E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_15125 7d522b5a0427e5e76009029dde5bd178 142 SUPERFAMILY SSF54593 1 136 7.75E-32 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_15125 7d522b5a0427e5e76009029dde5bd178 142 Gene3D G3DSA:3.10.180.10 8 141 1.2E-44 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_15125 7d522b5a0427e5e76009029dde5bd178 142 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 5 135 1.9E-6 T 14-10-2018 IPR028973 PhnB-like LH59_12970 b4f3988de056f642641e39de28b14f5b 498 Gene3D G3DSA:3.20.20.140 67 421 5.9E-180 T 14-10-2018 LH59_12970 b4f3988de056f642641e39de28b14f5b 498 Gene3D G3DSA:3.30.1490.130 295 351 5.9E-180 T 14-10-2018 IPR023100 D-aminoacylase, insert domain superfamily GO:0016811 LH59_12970 b4f3988de056f642641e39de28b14f5b 498 SUPERFAMILY SSF51556 68 426 1.89E-85 T 14-10-2018 IPR032466 Metal-dependent hydrolase LH59_12970 b4f3988de056f642641e39de28b14f5b 498 Gene3D G3DSA:2.30.40.10 15 470 5.9E-180 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 LH59_12970 b4f3988de056f642641e39de28b14f5b 498 Pfam PF07969 Amidohydrolase family 57 470 1.5E-36 T 14-10-2018 IPR013108 Amidohydrolase 3 LH59_12970 b4f3988de056f642641e39de28b14f5b 498 SUPERFAMILY SSF51338 15 484 8.0E-20 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 LH59_13010 31371c23899f4a433442e6604f42a267 353 Pfam PF00107 Zinc-binding dehydrogenase 187 314 1.4E-21 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 LH59_13010 31371c23899f4a433442e6604f42a267 353 Gene3D G3DSA:3.40.50.720 159 300 1.3E-93 T 14-10-2018 LH59_13010 31371c23899f4a433442e6604f42a267 353 SUPERFAMILY SSF50129 1 171 2.36E-37 T 14-10-2018 IPR011032 GroES-like superfamily LH59_13010 31371c23899f4a433442e6604f42a267 353 SUPERFAMILY SSF51735 147 319 4.51E-32 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_13010 31371c23899f4a433442e6604f42a267 353 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 71 85 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 LH59_13010 31371c23899f4a433442e6604f42a267 353 Gene3D G3DSA:3.90.180.10 18 343 1.3E-93 T 14-10-2018 LH59_13010 31371c23899f4a433442e6604f42a267 353 SMART SM00829 8 350 7.1E-4 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 LH59_13010 31371c23899f4a433442e6604f42a267 353 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 140 3.5E-30 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 LH59_13690 3821f126b8cb01f8af5b46752b225eae 106 Pfam PF00355 Rieske [2Fe-2S] domain 3 90 1.9E-17 T 14-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 LH59_13690 3821f126b8cb01f8af5b46752b225eae 106 SUPERFAMILY SSF50022 1 103 1.28E-28 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 LH59_13690 3821f126b8cb01f8af5b46752b225eae 106 Gene3D G3DSA:2.102.10.10 1 106 2.6E-31 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 LH59_09920 33e1d3ab5432c82b71fb37ad9900631b 677 Gene3D G3DSA:3.20.20.80 312 677 2.3E-145 T 14-10-2018 LH59_09920 33e1d3ab5432c82b71fb37ad9900631b 677 Gene3D G3DSA:3.20.20.370 45 311 1.1E-68 T 14-10-2018 LH59_09920 33e1d3ab5432c82b71fb37ad9900631b 677 TIGRFAM TIGR03938 deacetyl_PgaB: poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB 52 671 1.3E-264 T 14-10-2018 IPR023854 Poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB GO:0016810|GO:0043708 LH59_09920 33e1d3ab5432c82b71fb37ad9900631b 677 Pfam PF01522 Polysaccharide deacetylase 105 273 2.5E-26 T 14-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 LH59_09920 33e1d3ab5432c82b71fb37ad9900631b 677 SUPERFAMILY SSF88713 69 280 9.89E-35 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 LH59_09920 33e1d3ab5432c82b71fb37ad9900631b 677 Pfam PF14883 Hypothetical glycosyl hydrolase family 13 321 651 3.6E-149 T 14-10-2018 IPR032772 Poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB, C-terminal LH59_14255 86f8e90b7259abbcf5f9286bd3d00702 115 Gene3D G3DSA:3.10.180.10 9 115 8.3E-14 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_14255 86f8e90b7259abbcf5f9286bd3d00702 115 SUPERFAMILY SSF54593 12 114 1.83E-14 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_20340 bb945bc4912855537bb8f2d47b5c2feb 257 Hamap MF_00575 UDP-2,3-diacylglucosamine hydrolase [lpxH]. 1 256 94.021 T 14-10-2018 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 LH59_20340 bb945bc4912855537bb8f2d47b5c2feb 257 Gene3D G3DSA:3.60.21.10 11 224 2.6E-10 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like LH59_20340 bb945bc4912855537bb8f2d47b5c2feb 257 Pfam PF00149 Calcineurin-like phosphoesterase 9 208 2.3E-6 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 LH59_20340 bb945bc4912855537bb8f2d47b5c2feb 257 SUPERFAMILY SSF56300 11 249 3.63E-23 T 14-10-2018 LH59_20340 bb945bc4912855537bb8f2d47b5c2feb 257 TIGRFAM TIGR01854 lipid_A_lpxH: UDP-2,3-diacylglucosamine diphosphatase 12 229 7.3E-65 T 14-10-2018 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 LH59_18835 2daff65178ca65afb4014c28b3dd7911 130 Pfam PF13767 Domain of unknown function (DUF4168) 43 118 5.8E-18 T 14-10-2018 IPR025433 Domain of unknown function DUF4168 LH59_00095 71cbde1548b773bb3a798bed5f224365 298 Gene3D G3DSA:2.60.120.620 1 246 5.3E-63 T 14-10-2018 LH59_00095 71cbde1548b773bb3a798bed5f224365 298 SUPERFAMILY SSF51197 4 234 1.28E-47 T 14-10-2018 LH59_00095 71cbde1548b773bb3a798bed5f224365 298 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 15 223 1.3E-27 T 14-10-2018 IPR008775 Phytanoyl-CoA dioxygenase LH59_23975 aab65e9feddd9509d89ef4fdc49dec57 456 SUPERFAMILY SSF103473 11 453 3.14E-37 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_23975 aab65e9feddd9509d89ef4fdc49dec57 456 PRINTS PR01035 Tetracycline resistance protein signature 19 35 2.0E-5 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 LH59_23975 aab65e9feddd9509d89ef4fdc49dec57 456 PRINTS PR01035 Tetracycline resistance protein signature 255 275 2.0E-5 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 LH59_23975 aab65e9feddd9509d89ef4fdc49dec57 456 PRINTS PR01035 Tetracycline resistance protein signature 133 155 2.0E-5 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 LH59_23975 aab65e9feddd9509d89ef4fdc49dec57 456 Pfam PF07690 Major Facilitator Superfamily 15 405 2.0E-29 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_28125 decb8d7285c5375f2ad4279859e1c9d4 639 Pfam PF13932 GidA associated domain 403 624 1.6E-76 T 14-10-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 LH59_28125 decb8d7285c5375f2ad4279859e1c9d4 639 SUPERFAMILY SSF51905 6 262 1.16E-48 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_28125 decb8d7285c5375f2ad4279859e1c9d4 639 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 274 288 - T 14-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 LH59_28125 decb8d7285c5375f2ad4279859e1c9d4 639 SMART SM01228 554 625 6.6E-43 T 14-10-2018 LH59_28125 decb8d7285c5375f2ad4279859e1c9d4 639 Gene3D G3DSA:1.10.10.1800 460 558 1.0E-27 T 14-10-2018 LH59_28125 decb8d7285c5375f2ad4279859e1c9d4 639 Pfam PF01134 Glucose inhibited division protein A 8 399 3.3E-165 T 14-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 LH59_28125 decb8d7285c5375f2ad4279859e1c9d4 639 Gene3D G3DSA:3.50.50.60 2 219 9.7E-86 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_28125 decb8d7285c5375f2ad4279859e1c9d4 639 Gene3D G3DSA:3.50.50.60 296 459 8.0E-58 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_28125 decb8d7285c5375f2ad4279859e1c9d4 639 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 369 392 - T 14-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 LH59_28125 decb8d7285c5375f2ad4279859e1c9d4 639 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 5 632 42.756 T 14-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 LH59_28125 decb8d7285c5375f2ad4279859e1c9d4 639 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 7 629 1.7E-270 T 14-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 LH59_28125 decb8d7285c5375f2ad4279859e1c9d4 639 Gene3D G3DSA:1.10.150.570 578 631 1.0E-24 T 14-10-2018 LH59_01845 ac54bec94fc9a85d8e39452fbe64f756 124 SUPERFAMILY SSF110069 5 124 2.35E-49 T 14-10-2018 IPR036767 ApaG domain superfamily LH59_01845 ac54bec94fc9a85d8e39452fbe64f756 124 Pfam PF04379 ApaG domain 16 101 1.5E-37 T 14-10-2018 IPR007474 ApaG domain LH59_01845 ac54bec94fc9a85d8e39452fbe64f756 124 Hamap MF_00791 Protein ApaG [apaG]. 1 124 32.896 T 14-10-2018 IPR023065 Uncharacterised protein family ApaG LH59_01845 ac54bec94fc9a85d8e39452fbe64f756 124 Gene3D G3DSA:2.60.40.1470 1 124 1.1E-55 T 14-10-2018 IPR036767 ApaG domain superfamily LH59_25725 67660b9e6e26fff23cf20b230c7374ad 382 SUPERFAMILY SSF51395 4 375 4.21E-89 T 14-10-2018 LH59_25725 67660b9e6e26fff23cf20b230c7374ad 382 Pfam PF01070 FMN-dependent dehydrogenase 12 375 2.0E-125 T 14-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 LH59_25725 67660b9e6e26fff23cf20b230c7374ad 382 PIRSF PIRSF000138 1 379 2.5E-123 T 14-10-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 Reactome: R-HSA-9033241 LH59_25725 67660b9e6e26fff23cf20b230c7374ad 382 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 272 278 - T 14-10-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 Reactome: R-HSA-9033241 LH59_25725 67660b9e6e26fff23cf20b230c7374ad 382 Gene3D G3DSA:3.20.20.70 2 381 1.8E-124 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_16225 d0b4be3584d616dd2a8a238b226b5c29 300 Gene3D G3DSA:1.10.3720.10 87 299 6.4E-29 T 14-10-2018 IPR035906 MetI-like superfamily LH59_16225 d0b4be3584d616dd2a8a238b226b5c29 300 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 12 58 1.1E-10 T 14-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain LH59_16225 d0b4be3584d616dd2a8a238b226b5c29 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 299 4.1E-35 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_16225 d0b4be3584d616dd2a8a238b226b5c29 300 SUPERFAMILY SSF161098 92 284 7.72E-31 T 14-10-2018 IPR035906 MetI-like superfamily LH59_02765 ec6e4a81c832725fa04ae6d10c89e498 284 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 2 278 5.0E-88 T 14-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 LH59_02765 ec6e4a81c832725fa04ae6d10c89e498 284 Hamap MF_00158 Pantothenate synthetase [panC]. 2 280 37.388 T 14-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 LH59_02765 ec6e4a81c832725fa04ae6d10c89e498 284 Pfam PF02569 Pantoate-beta-alanine ligase 2 278 3.4E-94 T 14-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 LH59_02765 ec6e4a81c832725fa04ae6d10c89e498 284 Gene3D G3DSA:3.40.50.620 2 175 4.7E-71 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LH59_02765 ec6e4a81c832725fa04ae6d10c89e498 284 SUPERFAMILY SSF52374 2 281 8.89E-95 T 14-10-2018 LH59_02765 ec6e4a81c832725fa04ae6d10c89e498 284 Gene3D G3DSA:3.30.1300.10 176 278 1.4E-33 T 14-10-2018 LH59_02765 ec6e4a81c832725fa04ae6d10c89e498 284 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 19 74 9.7E-8 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 LH59_05145 9c4203d359f950533d74eca987277221 453 Pfam PF00270 DEAD/DEAH box helicase 14 188 4.0E-51 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 LH59_05145 9c4203d359f950533d74eca987277221 453 Gene3D G3DSA:3.40.50.300 205 381 1.1E-50 T 14-10-2018 LH59_05145 9c4203d359f950533d74eca987277221 453 SMART SM00490 250 331 4.1E-34 T 14-10-2018 IPR001650 Helicase, C-terminal LH59_05145 9c4203d359f950533d74eca987277221 453 SUPERFAMILY SSF52540 66 352 3.2E-76 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_05145 9c4203d359f950533d74eca987277221 453 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 145 153 - T 14-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site LH59_05145 9c4203d359f950533d74eca987277221 453 Gene3D G3DSA:3.40.50.300 1 203 8.5E-77 T 14-10-2018 LH59_05145 9c4203d359f950533d74eca987277221 453 Pfam PF00271 Helicase conserved C-terminal domain 225 331 2.5E-28 T 14-10-2018 IPR001650 Helicase, C-terminal LH59_05145 9c4203d359f950533d74eca987277221 453 SMART SM00487 9 214 2.8E-62 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain LH59_10135 8ae604ec558c91f08fb64888bd59c5f1 545 ProSitePatterns PS00455 Putative AMP-binding domain signature. 186 197 - T 14-10-2018 IPR020845 AMP-binding, conserved site LH59_10135 8ae604ec558c91f08fb64888bd59c5f1 545 Pfam PF00501 AMP-binding enzyme 26 443 1.5E-90 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 LH59_10135 8ae604ec558c91f08fb64888bd59c5f1 545 SUPERFAMILY SSF56801 11 536 1.07E-138 T 14-10-2018 LH59_10135 8ae604ec558c91f08fb64888bd59c5f1 545 Gene3D G3DSA:3.30.300.310 439 540 1.0E-33 T 14-10-2018 LH59_10135 8ae604ec558c91f08fb64888bd59c5f1 545 Gene3D G3DSA:3.40.50.12780 8 438 3.8E-104 T 14-10-2018 LH59_10135 8ae604ec558c91f08fb64888bd59c5f1 545 Pfam PF13193 AMP-binding enzyme C-terminal domain 452 526 9.6E-21 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain LH59_02155 eb3c2c04dc3dc47b19702bdf2aeec4e5 277 Gene3D G3DSA:1.10.12.10 216 275 2.7E-31 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal LH59_02155 eb3c2c04dc3dc47b19702bdf2aeec4e5 277 SUPERFAMILY SSF52096 35 271 1.56E-63 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily LH59_02155 eb3c2c04dc3dc47b19702bdf2aeec4e5 277 Gene3D G3DSA:3.90.226.10 2 215 2.5E-61 T 14-10-2018 LH59_02155 eb3c2c04dc3dc47b19702bdf2aeec4e5 277 Pfam PF00378 Enoyl-CoA hydratase/isomerase 37 272 6.7E-40 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 LH59_02155 eb3c2c04dc3dc47b19702bdf2aeec4e5 277 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 116 136 - T 14-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 LH59_15690 4a0c76ff6413f0da8e83e5c2d0fa5284 155 SUPERFAMILY SSF46785 11 150 1.76E-30 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_15690 4a0c76ff6413f0da8e83e5c2d0fa5284 155 SMART SM00347 38 138 1.0E-14 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_15690 4a0c76ff6413f0da8e83e5c2d0fa5284 155 Pfam PF01047 MarR family 45 103 7.5E-12 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_15690 4a0c76ff6413f0da8e83e5c2d0fa5284 155 Gene3D G3DSA:1.10.10.10 2 151 6.7E-32 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_17915 0eed2450accd802fbe7cc70f2aaf7017 463 PRINTS PR00762 Chloride channel signature 88 105 3.5E-26 T 14-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 LH59_17915 0eed2450accd802fbe7cc70f2aaf7017 463 PRINTS PR00762 Chloride channel signature 348 368 3.5E-26 T 14-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 LH59_17915 0eed2450accd802fbe7cc70f2aaf7017 463 PRINTS PR00762 Chloride channel signature 378 394 3.5E-26 T 14-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 LH59_17915 0eed2450accd802fbe7cc70f2aaf7017 463 PRINTS PR00762 Chloride channel signature 122 141 3.5E-26 T 14-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 LH59_17915 0eed2450accd802fbe7cc70f2aaf7017 463 PRINTS PR00762 Chloride channel signature 396 415 3.5E-26 T 14-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 LH59_17915 0eed2450accd802fbe7cc70f2aaf7017 463 PRINTS PR00762 Chloride channel signature 178 197 3.5E-26 T 14-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 LH59_17915 0eed2450accd802fbe7cc70f2aaf7017 463 Pfam PF00654 Voltage gated chloride channel 77 428 4.0E-70 T 14-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 LH59_17915 0eed2450accd802fbe7cc70f2aaf7017 463 Gene3D G3DSA:1.10.3080.10 23 447 1.5E-75 T 14-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 LH59_17915 0eed2450accd802fbe7cc70f2aaf7017 463 SUPERFAMILY SSF81340 11 443 2.62E-85 T 14-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 LH59_15720 d2222d908d8a18d7fd80cb5a23b2e2d1 277 Gene3D G3DSA:3.40.50.1820 10 269 1.8E-63 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_15720 d2222d908d8a18d7fd80cb5a23b2e2d1 277 Pfam PF00561 alpha/beta hydrolase fold 38 261 6.2E-17 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_15720 d2222d908d8a18d7fd80cb5a23b2e2d1 277 SUPERFAMILY SSF53474 14 274 8.99E-48 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_01095 947d14c2e4d5cedb295e553b1daf1fd0 283 TIGRFAM TIGR02821 fghA_ester_D: S-formylglutathione hydrolase 2 278 8.7E-139 T 14-10-2018 IPR014186 S-formylglutathione hydrolase GO:0018738|GO:0046294 KEGG: 00680+3.1.2.12|MetaCyc: PWY-1801|Reactome: R-HSA-156590 LH59_01095 947d14c2e4d5cedb295e553b1daf1fd0 283 SUPERFAMILY SSF53474 1 279 1.32E-87 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_01095 947d14c2e4d5cedb295e553b1daf1fd0 283 Gene3D G3DSA:3.40.50.1820 1 279 7.0E-88 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_01095 947d14c2e4d5cedb295e553b1daf1fd0 283 Pfam PF00756 Putative esterase 21 273 1.4E-53 T 14-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 LH59_09490 cf1c83e68544c7482ca19e381bcf95e8 177 SUPERFAMILY SSF109604 19 62 3.98E-7 T 14-10-2018 LH59_09490 cf1c83e68544c7482ca19e381bcf95e8 177 Gene3D G3DSA:1.10.3210.10 2 177 2.6E-60 T 14-10-2018 LH59_09490 cf1c83e68544c7482ca19e381bcf95e8 177 TIGRFAM TIGR03276 Phn-HD: phosphonate degradation operons associated HDIG domain protein 3 174 3.2E-70 T 14-10-2018 IPR017670 Phosphonate degradation operon associated HDIG domain protein LH59_09490 cf1c83e68544c7482ca19e381bcf95e8 177 Pfam PF01966 HD domain 28 85 3.1E-6 T 14-10-2018 IPR006674 HD domain LH59_23485 8f4c7d7b4c785f4523a75786b0be649f 285 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 235 276 - T 14-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 LH59_23485 8f4c7d7b4c785f4523a75786b0be649f 285 SMART SM00342 198 280 2.9E-24 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_23485 8f4c7d7b4c785f4523a75786b0be649f 285 Pfam PF12852 Cupin 6 163 1.3E-27 T 14-10-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain LH59_23485 8f4c7d7b4c785f4523a75786b0be649f 285 SUPERFAMILY SSF51215 62 160 9.68E-5 T 14-10-2018 IPR037923 Transcription regulator HTH-like LH59_23485 8f4c7d7b4c785f4523a75786b0be649f 285 SUPERFAMILY SSF46689 181 231 2.06E-8 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_23485 8f4c7d7b4c785f4523a75786b0be649f 285 Pfam PF12833 Helix-turn-helix domain 204 280 9.1E-19 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_23485 8f4c7d7b4c785f4523a75786b0be649f 285 SUPERFAMILY SSF46689 234 281 4.12E-7 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_23485 8f4c7d7b4c785f4523a75786b0be649f 285 Gene3D G3DSA:1.10.10.60 182 284 5.2E-21 T 14-10-2018 LH59_03665 d44a4286c155b6e78889e58c30167997 287 Pfam PF03466 LysR substrate binding domain 89 286 3.8E-23 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_03665 d44a4286c155b6e78889e58c30167997 287 SUPERFAMILY SSF53850 90 286 5.79E-26 T 14-10-2018 LH59_03665 d44a4286c155b6e78889e58c30167997 287 SUPERFAMILY SSF46785 4 88 1.42E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_03665 d44a4286c155b6e78889e58c30167997 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 2.6E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_03665 d44a4286c155b6e78889e58c30167997 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 2.6E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_03665 d44a4286c155b6e78889e58c30167997 287 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 2.6E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_03665 d44a4286c155b6e78889e58c30167997 287 Gene3D G3DSA:3.40.190.290 94 270 2.6E-18 T 14-10-2018 LH59_03665 d44a4286c155b6e78889e58c30167997 287 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 1.6E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_03665 d44a4286c155b6e78889e58c30167997 287 Gene3D G3DSA:1.10.10.10 1 90 2.1E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_27505 82edf5dcec311ab8b4444a2f31a8ff0e 104 Pfam PF09723 Zinc ribbon domain 1 41 3.2E-16 T 14-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain LH59_27505 82edf5dcec311ab8b4444a2f31a8ff0e 104 SMART SM00834 1 42 3.3E-18 T 14-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain LH59_27505 82edf5dcec311ab8b4444a2f31a8ff0e 104 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 52 7.5E-22 T 14-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain LH59_18710 acdc81daeb1b112dfe8823790aca70d8 123 Pfam PF07237 Protein of unknown function (DUF1428) 3 102 9.7E-35 T 14-10-2018 IPR009874 Protein of unknown function DUF1428 LH59_18710 acdc81daeb1b112dfe8823790aca70d8 123 PIRSF PIRSF007028 2 118 5.9E-47 T 14-10-2018 IPR009874 Protein of unknown function DUF1428 LH59_18710 acdc81daeb1b112dfe8823790aca70d8 123 Gene3D G3DSA:3.30.70.100 1 118 5.1E-37 T 14-10-2018 LH59_18710 acdc81daeb1b112dfe8823790aca70d8 123 SUPERFAMILY SSF54909 3 116 5.36E-39 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel LH59_13390 150c7e0c3f06fc8a14de2c30f9678f13 201 SUPERFAMILY SSF74653 94 183 5.36E-10 T 14-10-2018 LH59_13390 150c7e0c3f06fc8a14de2c30f9678f13 201 Gene3D G3DSA:3.55.50.30 8 80 2.8E-22 T 14-10-2018 LH59_13390 150c7e0c3f06fc8a14de2c30f9678f13 201 SMART SM00965 32 83 3.1E-9 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 LH59_13390 150c7e0c3f06fc8a14de2c30f9678f13 201 Gene3D G3DSA:3.30.1150.10 81 193 6.3E-7 T 14-10-2018 LH59_13390 150c7e0c3f06fc8a14de2c30f9678f13 201 Pfam PF13103 TonB C terminal 104 178 8.6E-6 T 14-10-2018 LH59_13390 150c7e0c3f06fc8a14de2c30f9678f13 201 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 131 185 2.3E-7 T 14-10-2018 IPR006260 TonB/TolA, C-terminal LH59_12940 20cbd5ac31306b7a763cf40f691cfbbf 308 Pfam PF02653 Branched-chain amino acid transport system / permease component 12 292 1.5E-51 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_20545 42dcf6b343e26b75237eb35f162a90f0 302 SUPERFAMILY SSF74650 15 293 2.2E-46 T 14-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 LH59_20545 42dcf6b343e26b75237eb35f162a90f0 302 Pfam PF01263 Aldose 1-epimerase 17 292 7.8E-28 T 14-10-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 LH59_20545 42dcf6b343e26b75237eb35f162a90f0 302 Gene3D G3DSA:2.70.98.10 9 297 5.4E-69 T 14-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 LH59_12055 d8c8fd841fbaa8640d26fccda268a585 226 Pfam PF01965 DJ-1/PfpI family 25 222 2.9E-16 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 LH59_12055 d8c8fd841fbaa8640d26fccda268a585 226 Gene3D G3DSA:3.40.50.880 1 225 4.0E-81 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_12055 d8c8fd841fbaa8640d26fccda268a585 226 SUPERFAMILY SSF52317 2 224 8.68E-76 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_23950 ddf6e07b95cfb97ef7acccae3674d80c 311 PIRSF PIRSF001365 1 304 2.6E-59 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_23950 ddf6e07b95cfb97ef7acccae3674d80c 311 Pfam PF00701 Dihydrodipicolinate synthetase family 6 285 4.9E-49 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_23950 ddf6e07b95cfb97ef7acccae3674d80c 311 PRINTS PR00146 Dihydrodipicolinate synthase signature 75 93 4.9E-7 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_23950 ddf6e07b95cfb97ef7acccae3674d80c 311 PRINTS PR00146 Dihydrodipicolinate synthase signature 39 60 4.9E-7 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_23950 ddf6e07b95cfb97ef7acccae3674d80c 311 PRINTS PR00146 Dihydrodipicolinate synthase signature 132 149 4.9E-7 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_23950 ddf6e07b95cfb97ef7acccae3674d80c 311 Gene3D G3DSA:3.20.20.70 1 298 1.5E-70 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_23950 ddf6e07b95cfb97ef7acccae3674d80c 311 SMART SM01130 5 296 2.5E-71 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_23950 ddf6e07b95cfb97ef7acccae3674d80c 311 SUPERFAMILY SSF51569 2 297 7.95E-71 T 14-10-2018 LH59_14635 71252048f2a972abd020267a5a997193 476 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 79 7.7E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_14635 71252048f2a972abd020267a5a997193 476 SUPERFAMILY SSF46785 12 90 2.32E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_14635 71252048f2a972abd020267a5a997193 476 SMART SM00345 20 79 8.6E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_14635 71252048f2a972abd020267a5a997193 476 Gene3D G3DSA:3.90.1150.10 115 465 1.1E-65 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_14635 71252048f2a972abd020267a5a997193 476 Gene3D G3DSA:3.40.640.10 151 367 1.1E-65 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_14635 71252048f2a972abd020267a5a997193 476 SUPERFAMILY SSF53383 110 472 6.74E-68 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_14635 71252048f2a972abd020267a5a997193 476 Pfam PF00155 Aminotransferase class I and II 147 458 8.5E-30 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LH59_14635 71252048f2a972abd020267a5a997193 476 Gene3D G3DSA:1.10.10.10 13 114 6.1E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_23850 382480a5261771acc1a0a1d3a8aed336 267 PRINTS PR00069 Aldo-keto reductase signature 186 210 2.0E-46 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 LH59_23850 382480a5261771acc1a0a1d3a8aed336 267 PRINTS PR00069 Aldo-keto reductase signature 25 49 2.0E-46 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 LH59_23850 382480a5261771acc1a0a1d3a8aed336 267 PRINTS PR00069 Aldo-keto reductase signature 114 131 2.0E-46 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 LH59_23850 382480a5261771acc1a0a1d3a8aed336 267 PRINTS PR00069 Aldo-keto reductase signature 81 99 2.0E-46 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 LH59_23850 382480a5261771acc1a0a1d3a8aed336 267 PRINTS PR00069 Aldo-keto reductase signature 149 178 2.0E-46 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 LH59_23850 382480a5261771acc1a0a1d3a8aed336 267 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 29 46 - T 14-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 LH59_23850 382480a5261771acc1a0a1d3a8aed336 267 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 114 131 - T 14-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 LH59_23850 382480a5261771acc1a0a1d3a8aed336 267 PIRSF PIRSF000097 1 265 4.3E-67 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 LH59_23850 382480a5261771acc1a0a1d3a8aed336 267 Pfam PF00248 Aldo/keto reductase family 16 251 2.7E-46 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain LH59_23850 382480a5261771acc1a0a1d3a8aed336 267 SUPERFAMILY SSF51430 2 257 5.76E-79 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily LH59_23850 382480a5261771acc1a0a1d3a8aed336 267 Gene3D G3DSA:3.20.20.100 1 267 2.6E-91 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily LH59_19790 e02eba613f791dd5886fd8f658225a3c 333 Pfam PF00482 Type II secretion system (T2SS), protein F 188 314 4.2E-13 T 14-10-2018 IPR018076 Type II secretion system F domain LH59_25815 c986c4128ff56e09eedee71d4c36f915 273 SUPERFAMILY SSF53223 3 106 5.18E-25 T 14-10-2018 LH59_25815 c986c4128ff56e09eedee71d4c36f915 273 Gene3D G3DSA:3.40.50.10860 7 107 2.7E-70 T 14-10-2018 LH59_25815 c986c4128ff56e09eedee71d4c36f915 273 Gene3D G3DSA:3.40.50.720 108 247 2.7E-70 T 14-10-2018 LH59_25815 c986c4128ff56e09eedee71d4c36f915 273 SUPERFAMILY SSF51735 108 251 3.03E-31 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_25815 c986c4128ff56e09eedee71d4c36f915 273 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 13 95 7.1E-19 T 14-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 LH59_02895 3ebcd37d0c0e28490c4bd73670fa1f9b 322 Pfam PF02653 Branched-chain amino acid transport system / permease component 32 294 1.7E-37 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_15840 c4eff7d7f54fe44d01f069a84fa70c42 554 Gene3D G3DSA:3.40.1350.10 480 550 7.0E-7 T 14-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 LH59_15840 c4eff7d7f54fe44d01f069a84fa70c42 554 Pfam PF08774 VRR-NUC domain 438 549 1.5E-27 T 14-10-2018 IPR014883 VRR-NUC domain GO:0016788 Reactome: R-HSA-6783310 LH59_15840 c4eff7d7f54fe44d01f069a84fa70c42 554 SMART SM00990 435 549 2.0E-41 T 14-10-2018 IPR014883 VRR-NUC domain GO:0016788 Reactome: R-HSA-6783310 LH59_26470 48f3e9bc07353b83b92937dec2ccc7c6 186 Gene3D G3DSA:1.20.1260.10 33 186 9.2E-54 T 14-10-2018 IPR012347 Ferritin-like LH59_26470 48f3e9bc07353b83b92937dec2ccc7c6 186 SUPERFAMILY SSF47240 40 185 2.59E-41 T 14-10-2018 IPR009078 Ferritin-like superfamily LH59_26470 48f3e9bc07353b83b92937dec2ccc7c6 186 Pfam PF00210 Ferritin-like domain 48 185 6.0E-32 T 14-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 LH59_26470 48f3e9bc07353b83b92937dec2ccc7c6 186 PIRSF PIRSF018063 22 186 5.6E-62 T 14-10-2018 IPR014490 DNA-binding protein from starved cells-like LH59_01910 c272951493cf36120d17e242cfad6b5b 251 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 228 250 2.9E-7 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal LH59_01910 c272951493cf36120d17e242cfad6b5b 251 Gene3D G3DSA:3.40.50.300 8 251 6.4E-58 T 14-10-2018 LH59_01910 c272951493cf36120d17e242cfad6b5b 251 Pfam PF00005 ABC transporter 28 181 2.2E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_01910 c272951493cf36120d17e242cfad6b5b 251 SUPERFAMILY SSF52540 11 249 4.0E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_01910 c272951493cf36120d17e242cfad6b5b 251 SMART SM00382 36 228 0.0074 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_01910 c272951493cf36120d17e242cfad6b5b 251 TIGRFAM TIGR03411 urea_trans_UrtD: urea ABC transporter, ATP-binding protein UrtD 11 251 1.3E-111 T 14-10-2018 IPR017781 ABC transporter, urea, ATP-binding protein, UrtD LH59_08950 b35b267fc31613844597a85b71a360de 212 TIGRFAM TIGR02661 MauD: methylamine dehydrogenase accessory protein MauD 4 191 8.4E-63 T 14-10-2018 IPR013478 Methylamine dehydrogenase accessory protein MauD GO:0030416 LH59_08950 b35b267fc31613844597a85b71a360de 212 SUPERFAMILY SSF52833 46 169 1.01E-18 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_08950 b35b267fc31613844597a85b71a360de 212 Gene3D G3DSA:3.40.30.10 45 205 1.1E-16 T 14-10-2018 LH59_08950 b35b267fc31613844597a85b71a360de 212 Pfam PF13098 Thioredoxin-like domain 76 175 3.9E-7 T 14-10-2018 IPR012336 Thioredoxin-like fold LH59_10180 7c577148ef20d215f66e673b49985664 886 SUPERFAMILY SSF52518 58 467 1.05E-121 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold LH59_10180 7c577148ef20d215f66e673b49985664 886 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 112 293 8.7E-6 T 14-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 LH59_10180 7c577148ef20d215f66e673b49985664 886 Gene3D G3DSA:3.40.50.920 705 885 1.9E-70 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 LH59_10180 7c577148ef20d215f66e673b49985664 886 PIRSF PIRSF000156 1 885 0.0 T 14-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 LH59_10180 7c577148ef20d215f66e673b49985664 886 SUPERFAMILY SSF52518 473 698 6.18E-95 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold LH59_10180 7c577148ef20d215f66e673b49985664 886 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 9 882 0.0 T 14-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 LH59_10180 7c577148ef20d215f66e673b49985664 886 Gene3D G3DSA:3.40.50.970 472 704 1.2E-106 T 14-10-2018 LH59_10180 7c577148ef20d215f66e673b49985664 886 Gene3D G3DSA:3.40.50.970 57 468 4.1E-115 T 14-10-2018 LH59_10180 7c577148ef20d215f66e673b49985664 886 SUPERFAMILY SSF52922 700 881 3.66E-56 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 LH59_02905 5d965e7cfc8ffa6e168d881c10ffb645 234 SUPERFAMILY SSF52540 2 231 8.21E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_02905 5d965e7cfc8ffa6e168d881c10ffb645 234 SMART SM00382 26 211 1.4E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_02905 5d965e7cfc8ffa6e168d881c10ffb645 234 Pfam PF00005 ABC transporter 19 162 2.7E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_02905 5d965e7cfc8ffa6e168d881c10ffb645 234 Gene3D G3DSA:3.40.50.300 1 234 9.5E-58 T 14-10-2018 LH59_02905 5d965e7cfc8ffa6e168d881c10ffb645 234 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_24320 22a5a7c83645326a7671d4c02d8ff43b 143 Pfam PF01042 Endoribonuclease L-PSP 16 138 1.3E-26 T 14-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 LH59_24320 22a5a7c83645326a7671d4c02d8ff43b 143 SUPERFAMILY SSF55298 13 140 2.67E-33 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 LH59_24320 22a5a7c83645326a7671d4c02d8ff43b 143 Gene3D G3DSA:3.30.1330.40 4 140 1.3E-41 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 LH59_24985 c7ff6523273d9c50623e0937b71877c1 917 Gene3D G3DSA:3.40.50.300 272 515 3.0E-61 T 14-10-2018 LH59_24985 c7ff6523273d9c50623e0937b71877c1 917 Pfam PF00005 ABC transporter 294 437 3.7E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_24985 c7ff6523273d9c50623e0937b71877c1 917 Pfam PF12698 ABC-2 family transporter protein 576 904 3.1E-35 T 14-10-2018 LH59_24985 c7ff6523273d9c50623e0937b71877c1 917 SMART SM00382 302 487 8.5E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_24985 c7ff6523273d9c50623e0937b71877c1 917 SMART SM00382 37 264 2.1E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_24985 c7ff6523273d9c50623e0937b71877c1 917 SUPERFAMILY SSF52540 277 496 1.59E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_24985 c7ff6523273d9c50623e0937b71877c1 917 Pfam PF00005 ABC transporter 28 175 1.4E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_24985 c7ff6523273d9c50623e0937b71877c1 917 SUPERFAMILY SSF52540 11 239 3.63E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_24985 c7ff6523273d9c50623e0937b71877c1 917 Gene3D G3DSA:3.40.50.300 1 249 7.0E-62 T 14-10-2018 LH59_24985 c7ff6523273d9c50623e0937b71877c1 917 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_22040 f5279a4408576099c72d83dc58617e4d 270 SUPERFAMILY SSF52540 7 228 1.21E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_22040 f5279a4408576099c72d83dc58617e4d 270 Gene3D G3DSA:3.40.50.300 3 220 2.1E-59 T 14-10-2018 LH59_22040 f5279a4408576099c72d83dc58617e4d 270 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_22040 f5279a4408576099c72d83dc58617e4d 270 SMART SM00382 37 217 3.3E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_22040 f5279a4408576099c72d83dc58617e4d 270 Pfam PF00005 ABC transporter 29 167 1.7E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_15025 16c65a9bf538e5d2ee7894d76a1abbe9 244 Gene3D G3DSA:3.40.50.720 1 243 4.9E-56 T 14-10-2018 LH59_15025 16c65a9bf538e5d2ee7894d76a1abbe9 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 5.5E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_15025 16c65a9bf538e5d2ee7894d76a1abbe9 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 5.5E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_15025 16c65a9bf538e5d2ee7894d76a1abbe9 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 5.5E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_15025 16c65a9bf538e5d2ee7894d76a1abbe9 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 5.5E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_15025 16c65a9bf538e5d2ee7894d76a1abbe9 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 5.5E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_15025 16c65a9bf538e5d2ee7894d76a1abbe9 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 5.5E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_15025 16c65a9bf538e5d2ee7894d76a1abbe9 244 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 240 1.3E-40 T 14-10-2018 LH59_15025 16c65a9bf538e5d2ee7894d76a1abbe9 244 SUPERFAMILY SSF51735 1 243 7.67E-57 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_16540 287378d5da6edea3ebb60885b7908aa7 312 Pfam PF00701 Dihydrodipicolinate synthetase family 7 304 3.0E-33 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_16540 287378d5da6edea3ebb60885b7908aa7 312 Gene3D G3DSA:3.20.20.70 4 310 9.2E-68 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_16540 287378d5da6edea3ebb60885b7908aa7 312 PIRSF PIRSF001365 4 312 1.7E-54 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_16540 287378d5da6edea3ebb60885b7908aa7 312 SUPERFAMILY SSF51569 4 310 2.51E-65 T 14-10-2018 LH59_16540 287378d5da6edea3ebb60885b7908aa7 312 SMART SM01130 6 308 6.2E-67 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_06530 01f0683c75632e8adec2fbde28d5540d 169 Pfam PF03872 Anti sigma-E protein RseA, N-terminal domain 17 80 2.1E-11 T 14-10-2018 IPR005572 Anti sigma-E protein RseA, N-terminal GO:0016989 LH59_06530 01f0683c75632e8adec2fbde28d5540d 169 SUPERFAMILY SSF89069 16 79 3.79E-13 T 14-10-2018 IPR036147 Anti sigma-E protein RseA, N-terminal domain superfamily GO:0016989 LH59_06530 01f0683c75632e8adec2fbde28d5540d 169 Gene3D G3DSA:1.10.10.880 16 79 5.8E-11 T 14-10-2018 IPR036147 Anti sigma-E protein RseA, N-terminal domain superfamily GO:0016989 LH59_09415 aaa30975a246a5bc0514653917dc6d57 504 Gene3D G3DSA:1.20.1600.10 40 443 7.9E-80 T 14-10-2018 LH59_09415 aaa30975a246a5bc0514653917dc6d57 504 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 40 442 2.3E-83 T 14-10-2018 IPR010130 Type I secretion outer membrane protein, TolC GO:0015562|GO:0019867|GO:0055085 LH59_09415 aaa30975a246a5bc0514653917dc6d57 504 SUPERFAMILY SSF56954 41 440 1.7E-77 T 14-10-2018 LH59_09415 aaa30975a246a5bc0514653917dc6d57 504 Pfam PF02321 Outer membrane efflux protein 256 432 9.0E-27 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 LH59_09415 aaa30975a246a5bc0514653917dc6d57 504 Pfam PF02321 Outer membrane efflux protein 42 229 2.1E-20 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 LH59_07935 0cd9d5617fadeb880c14b4445be82e64 470 SUPERFAMILY SSF46458 45 155 4.36E-12 T 14-10-2018 IPR009050 Globin-like superfamily LH59_07935 0cd9d5617fadeb880c14b4445be82e64 470 Gene3D G3DSA:1.10.490.10 22 171 5.7E-45 T 14-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 LH59_07935 0cd9d5617fadeb880c14b4445be82e64 470 Pfam PF00990 Diguanylate cyclase, GGDEF domain 311 466 4.9E-44 T 14-10-2018 IPR000160 GGDEF domain LH59_07935 0cd9d5617fadeb880c14b4445be82e64 470 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 308 468 4.6E-50 T 14-10-2018 IPR000160 GGDEF domain LH59_07935 0cd9d5617fadeb880c14b4445be82e64 470 SUPERFAMILY SSF55073 314 468 2.16E-45 T 14-10-2018 IPR029787 Nucleotide cyclase LH59_07935 0cd9d5617fadeb880c14b4445be82e64 470 Gene3D G3DSA:3.30.70.270 306 469 8.5E-53 T 14-10-2018 LH59_07935 0cd9d5617fadeb880c14b4445be82e64 470 Pfam PF11563 Protoglobin 42 175 3.3E-8 T 14-10-2018 LH59_07935 0cd9d5617fadeb880c14b4445be82e64 470 SMART SM00267 297 470 2.9E-55 T 14-10-2018 IPR000160 GGDEF domain LH59_14765 3d31f5348ca0305b958e467f3fcf5447 695 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 467 595 8.7E-36 T 14-10-2018 IPR025299 CstA, C-terminal domain LH59_14765 3d31f5348ca0305b958e467f3fcf5447 695 Pfam PF02554 Carbon starvation protein CstA 36 412 3.5E-173 T 14-10-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 LH59_02890 a676a7fe224fc7f2c2b0aa2e5f2e80f2 306 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 294 2.1E-34 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_14530 f37a5aec7d8c87c443b4d1774ba0b930 227 Gene3D G3DSA:1.20.950.20 1 219 2.5E-75 T 14-10-2018 LH59_14530 f37a5aec7d8c87c443b4d1774ba0b930 227 SUPERFAMILY SSF103501 1 226 3.14E-66 T 14-10-2018 IPR036197 NarG-like superfamily LH59_14530 f37a5aec7d8c87c443b4d1774ba0b930 227 TIGRFAM TIGR00351 narI: respiratory nitrate reductase, gamma subunit 2 227 4.7E-77 T 14-10-2018 IPR003816 Nitrate reductase, gamma subunit GO:0008940|GO:0009325|GO:0055114 LH59_14530 f37a5aec7d8c87c443b4d1774ba0b930 227 Pfam PF02665 Nitrate reductase gamma subunit 5 227 4.7E-81 T 14-10-2018 IPR023234 NarG-like domain LH59_24110 8d86caf7d6eecfac6caf1d50e3950760 255 Gene3D G3DSA:3.10.450.70 28 96 1.3E-17 T 14-10-2018 IPR009094 Disulphide bond isomerase DsbC/G, N-terminal domain superfamily GO:0042597 LH59_24110 8d86caf7d6eecfac6caf1d50e3950760 255 Pfam PF13098 Thioredoxin-like domain 121 250 1.0E-13 T 14-10-2018 IPR012336 Thioredoxin-like fold LH59_24110 8d86caf7d6eecfac6caf1d50e3950760 255 SUPERFAMILY SSF54423 28 85 7.85E-11 T 14-10-2018 IPR009094 Disulphide bond isomerase DsbC/G, N-terminal domain superfamily GO:0042597 LH59_24110 8d86caf7d6eecfac6caf1d50e3950760 255 Gene3D G3DSA:3.40.30.10 111 254 1.4E-37 T 14-10-2018 LH59_24110 8d86caf7d6eecfac6caf1d50e3950760 255 SUPERFAMILY SSF52833 94 250 2.93E-31 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_05445 d70cf73874a131d19cf3f288388d6a5e 91 TIGRFAM TIGR03647 Na_symport_sm: putative solute:sodium symporter small subunit 14 83 8.5E-26 T 14-10-2018 IPR019886 Sodium symporter small subunit, predicted LH59_05445 d70cf73874a131d19cf3f288388d6a5e 91 Pfam PF13937 Domain of unknown function (DUF4212) 14 83 1.2E-23 T 14-10-2018 IPR019886 Sodium symporter small subunit, predicted LH59_13720 ac755d42d36709483db58cabd0bf5b2b 425 SUPERFAMILY SSF51735 7 245 3.97E-36 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_13720 ac755d42d36709483db58cabd0bf5b2b 425 Pfam PF13460 NAD(P)H-binding 14 151 2.6E-13 T 14-10-2018 IPR016040 NAD(P)-binding domain LH59_13720 ac755d42d36709483db58cabd0bf5b2b 425 Gene3D G3DSA:3.40.50.720 2 209 2.3E-38 T 14-10-2018 LH59_13720 ac755d42d36709483db58cabd0bf5b2b 425 Pfam PF13781 DoxX-like family 316 415 1.2E-24 T 14-10-2018 IPR025695 DoxX-like family LH59_06140 fee605fd1b946e751cd4749c164353b6 357 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 233 246 - T 14-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06140 fee605fd1b946e751cd4749c164353b6 357 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 21 352 24.771 T 14-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06140 fee605fd1b946e751cd4749c164353b6 357 Pfam PF00146 NADH dehydrogenase 27 345 2.9E-125 T 14-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_04620 68a3db593868bcefff769d5dd1ab6c8e 327 SUPERFAMILY SSF53850 115 288 1.09E-5 T 14-10-2018 LH59_04620 68a3db593868bcefff769d5dd1ab6c8e 327 Gene3D G3DSA:3.40.190.10 129 252 1.9E-114 T 14-10-2018 LH59_04620 68a3db593868bcefff769d5dd1ab6c8e 327 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 323 2.0E-77 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_04620 68a3db593868bcefff769d5dd1ab6c8e 327 PIRSF PIRSF017082 1 326 8.9E-80 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_04620 68a3db593868bcefff769d5dd1ab6c8e 327 Gene3D G3DSA:3.40.190.150 29 312 1.9E-114 T 14-10-2018 LH59_25205 967cba2bc2150c714869c2bb18482f2a 319 Pfam PF00753 Metallo-beta-lactamase superfamily 33 214 9.6E-16 T 14-10-2018 IPR001279 Metallo-beta-lactamase LH59_25205 967cba2bc2150c714869c2bb18482f2a 319 SMART SM00849 33 222 9.9E-17 T 14-10-2018 IPR001279 Metallo-beta-lactamase LH59_25205 967cba2bc2150c714869c2bb18482f2a 319 SUPERFAMILY SSF56281 15 310 2.38E-55 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like LH59_25205 967cba2bc2150c714869c2bb18482f2a 319 Gene3D G3DSA:3.60.15.10 11 239 6.9E-46 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like LH59_07280 901a8f5053d6c125ed6b08067db65cc0 285 Gene3D G3DSA:1.10.3660.10 178 283 4.6E-33 T 14-10-2018 LH59_07280 901a8f5053d6c125ed6b08067db65cc0 285 SUPERFAMILY SSF51735 5 170 2.95E-48 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_07280 901a8f5053d6c125ed6b08067db65cc0 285 SUPERFAMILY SSF48179 174 282 3.51E-31 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 LH59_07280 901a8f5053d6c125ed6b08067db65cc0 285 Gene3D G3DSA:3.40.50.720 4 177 1.4E-51 T 14-10-2018 LH59_07280 901a8f5053d6c125ed6b08067db65cc0 285 Pfam PF02153 Prephenate dehydrogenase 17 272 2.2E-67 T 14-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 LH59_06120 ade2e5b51b93e7b0cf9ab10dbeb930c4 418 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 1 418 49.777 T 14-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06120 ade2e5b51b93e7b0cf9ab10dbeb930c4 418 SUPERFAMILY SSF56762 16 418 9.29E-138 T 14-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06120 ade2e5b51b93e7b0cf9ab10dbeb930c4 418 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 6 418 2.0E-184 T 14-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06120 ade2e5b51b93e7b0cf9ab10dbeb930c4 418 Gene3D G3DSA:1.10.645.20 4 418 9.5E-173 T 14-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06120 ade2e5b51b93e7b0cf9ab10dbeb930c4 418 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 43 54 - T 14-10-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_06120 ade2e5b51b93e7b0cf9ab10dbeb930c4 418 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 120 418 9.9E-123 T 14-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_08075 94a6d4394dc4cb0a89578cb97befd2ca 230 SMART SM00382 26 207 4.6E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_08075 94a6d4394dc4cb0a89578cb97befd2ca 230 SUPERFAMILY SSF52540 2 224 5.01E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_08075 94a6d4394dc4cb0a89578cb97befd2ca 230 Gene3D G3DSA:3.40.50.300 1 228 9.5E-57 T 14-10-2018 LH59_08075 94a6d4394dc4cb0a89578cb97befd2ca 230 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_08075 94a6d4394dc4cb0a89578cb97befd2ca 230 Pfam PF00005 ABC transporter 17 158 1.1E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_07225 c9a69b9277f5eb08e3f5f6f15ae841dd 736 Pfam PF03170 Bacterial cellulose synthase subunit 46 183 1.5E-6 T 14-10-2018 IPR018513 Cellulose synthase BcsB, bacterial GO:0006011|GO:0016020 LH59_07225 c9a69b9277f5eb08e3f5f6f15ae841dd 736 Gene3D G3DSA:2.60.120.260 45 174 7.8E-6 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily LH59_18335 5eb6cec86c3bba70d18b30b7d14c955a 356 Pfam PF04199 Putative cyclase 94 279 2.2E-13 T 14-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 LH59_18335 5eb6cec86c3bba70d18b30b7d14c955a 356 Gene3D G3DSA:3.50.30.50 97 356 5.6E-11 T 14-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 LH59_18335 5eb6cec86c3bba70d18b30b7d14c955a 356 SUPERFAMILY SSF102198 100 355 1.7E-10 T 14-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 LH59_26175 63a0239969b7a85458ab04caf11791b4 261 PIRSF PIRSF006241 1 261 1.5E-93 T 14-10-2018 IPR026040 Hydroxypyruvate isomerase-like LH59_26175 63a0239969b7a85458ab04caf11791b4 261 Gene3D G3DSA:3.20.20.150 1 260 1.3E-71 T 14-10-2018 LH59_26175 63a0239969b7a85458ab04caf11791b4 261 SUPERFAMILY SSF51658 1 258 1.23E-75 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily LH59_26175 63a0239969b7a85458ab04caf11791b4 261 Pfam PF01261 Xylose isomerase-like TIM barrel 22 219 5.1E-28 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain LH59_03340 a5d1847f6a4da2ece25a8d4fc7fba4c8 384 Gene3D G3DSA:3.40.50.2300 29 330 2.6E-95 T 14-10-2018 LH59_03340 a5d1847f6a4da2ece25a8d4fc7fba4c8 384 Gene3D G3DSA:3.40.50.2300 144 276 2.6E-95 T 14-10-2018 LH59_03340 a5d1847f6a4da2ece25a8d4fc7fba4c8 384 Pfam PF13458 Periplasmic binding protein 26 361 4.3E-60 T 14-10-2018 IPR028081 Leucine-binding protein domain LH59_03340 a5d1847f6a4da2ece25a8d4fc7fba4c8 384 SUPERFAMILY SSF53822 26 360 1.47E-82 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_03340 a5d1847f6a4da2ece25a8d4fc7fba4c8 384 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 89 99 1.9E-12 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 LH59_03340 a5d1847f6a4da2ece25a8d4fc7fba4c8 384 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 26 42 1.9E-12 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 LH59_03340 a5d1847f6a4da2ece25a8d4fc7fba4c8 384 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 280 293 1.9E-12 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 LH59_03340 a5d1847f6a4da2ece25a8d4fc7fba4c8 384 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 48 64 1.9E-12 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 LH59_12835 b649b71b55a0bf642da1f5503250325d 826 SUPERFAMILY SSF48452 534 802 1.59E-11 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_12835 b649b71b55a0bf642da1f5503250325d 826 Gene3D G3DSA:1.25.40.10 585 826 1.1E-14 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_20710 46e602432067c82f29187d8ac566e331 184 SUPERFAMILY SSF49401 31 184 3.43E-29 T 14-10-2018 IPR008966 Adhesion domain superfamily LH59_20710 46e602432067c82f29187d8ac566e331 184 Gene3D G3DSA:2.60.40.1090 28 184 6.5E-31 T 14-10-2018 IPR036937 Fimbrial-type adhesion domain superfamily GO:0007155|GO:0009289 LH59_20710 46e602432067c82f29187d8ac566e331 184 Pfam PF00419 Fimbrial protein 32 184 3.1E-12 T 14-10-2018 IPR000259 Fimbrial-type adhesion domain GO:0007155|GO:0009289 LH59_16965 bd2286ba16580274e96308eb6359743b 225 Pfam PF01613 Flavin reductase like domain 22 162 1.2E-20 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 LH59_16965 bd2286ba16580274e96308eb6359743b 225 SUPERFAMILY SSF50475 1 177 4.71E-39 T 14-10-2018 LH59_16965 bd2286ba16580274e96308eb6359743b 225 SMART SM00903 19 172 3.0E-23 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 LH59_16965 bd2286ba16580274e96308eb6359743b 225 Gene3D G3DSA:2.30.110.10 1 210 1.1E-59 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 LH59_16235 b16c8051e9fae9788aa6c59037558c7a 339 SUPERFAMILY SSF52540 57 333 9.71E-69 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_16235 b16c8051e9fae9788aa6c59037558c7a 339 ProSitePatterns PS00211 ABC transporters family signature. 172 186 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_16235 b16c8051e9fae9788aa6c59037558c7a 339 Pfam PF00005 ABC transporter 49 199 2.1E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_16235 b16c8051e9fae9788aa6c59037558c7a 339 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 249 335 4.3E-29 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_16235 b16c8051e9fae9788aa6c59037558c7a 339 SMART SM00382 57 249 1.3E-18 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_16235 b16c8051e9fae9788aa6c59037558c7a 339 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 251 315 9.4E-19 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_16235 b16c8051e9fae9788aa6c59037558c7a 339 Gene3D G3DSA:3.40.50.300 13 339 1.3E-95 T 14-10-2018 LH59_21125 fefa424cbddd58969c4e0ab121e34385 394 Gene3D G3DSA:3.90.1150.10 43 386 1.0E-121 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_21125 fefa424cbddd58969c4e0ab121e34385 394 Gene3D G3DSA:3.40.640.10 58 295 1.0E-121 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_21125 fefa424cbddd58969c4e0ab121e34385 394 SUPERFAMILY SSF53383 12 393 5.92E-97 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_21125 fefa424cbddd58969c4e0ab121e34385 394 Pfam PF00155 Aminotransferase class I and II 43 388 1.2E-55 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LH59_21125 fefa424cbddd58969c4e0ab121e34385 394 TIGRFAM TIGR00858 bioF: 8-amino-7-oxononanoate synthase 21 389 1.1E-128 T 14-10-2018 IPR004723 8-amino-7-oxononanoate synthase, Archaea/Proteobacteria type GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 LH59_21125 fefa424cbddd58969c4e0ab121e34385 394 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 244 253 - T 14-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 LH59_24620 81ac738a5df4caf6705dc5065b864ecf 272 Pfam PF01370 NAD dependent epimerase/dehydratase family 11 169 1.2E-20 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 LH59_24620 81ac738a5df4caf6705dc5065b864ecf 272 SUPERFAMILY SSF51735 9 242 8.99E-41 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_24620 81ac738a5df4caf6705dc5065b864ecf 272 Gene3D G3DSA:3.40.50.720 8 232 2.2E-60 T 14-10-2018 LH59_14490 880f8d7cd1e8751098049c4bb1f0bd2e 296 Pfam PF01136 Peptidase family U32 112 247 9.8E-11 T 14-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 LH59_22780 52084ec08adbc945091d1465d0d58492 341 Pfam PF02562 PhoH-like protein 131 334 4.3E-95 T 14-10-2018 IPR003714 PhoH-like protein GO:0005524 LH59_22780 52084ec08adbc945091d1465d0d58492 341 Gene3D G3DSA:3.40.50.300 128 334 5.8E-75 T 14-10-2018 LH59_22780 52084ec08adbc945091d1465d0d58492 341 SUPERFAMILY SSF52540 130 309 1.98E-39 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_26665 6048d4d57bff1b5db3f235f19ce94686 204 Gene3D G3DSA:1.10.760.10 3 75 2.0E-16 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_26665 6048d4d57bff1b5db3f235f19ce94686 204 SUPERFAMILY SSF46626 6 80 2.02E-16 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_26665 6048d4d57bff1b5db3f235f19ce94686 204 Pfam PF00034 Cytochrome c 6 56 9.6E-6 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_26665 6048d4d57bff1b5db3f235f19ce94686 204 Pfam PF00034 Cytochrome c 109 178 1.3E-5 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_26665 6048d4d57bff1b5db3f235f19ce94686 204 SUPERFAMILY SSF46626 87 178 7.09E-17 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_26665 6048d4d57bff1b5db3f235f19ce94686 204 Gene3D G3DSA:1.10.760.10 84 177 7.6E-18 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_26665 6048d4d57bff1b5db3f235f19ce94686 204 PIRSF PIRSF000005 1 180 1.0E-60 T 14-10-2018 IPR024167 Cytochrome c4-like GO:0005506|GO:0009055|GO:0020037|GO:0042597 LH59_04885 cb0253afc95a5a9d6567a92b8f4835ed 163 Pfam PF12802 MarR family 44 102 1.1E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_04885 cb0253afc95a5a9d6567a92b8f4835ed 163 SUPERFAMILY SSF46785 17 149 3.07E-28 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_04885 cb0253afc95a5a9d6567a92b8f4835ed 163 SMART SM00347 38 138 7.5E-12 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_04885 cb0253afc95a5a9d6567a92b8f4835ed 163 ProSitePatterns PS01117 MarR-type HTH domain signature. 77 111 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site LH59_04885 cb0253afc95a5a9d6567a92b8f4835ed 163 Gene3D G3DSA:1.10.10.10 12 152 4.1E-32 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_00160 632041a386e79c2fc3e3f3ff8fad66f0 326 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 322 6.2E-89 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_00160 632041a386e79c2fc3e3f3ff8fad66f0 326 SUPERFAMILY SSF53850 115 289 1.38E-10 T 14-10-2018 LH59_00160 632041a386e79c2fc3e3f3ff8fad66f0 326 PIRSF PIRSF017082 1 325 8.8E-78 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_00160 632041a386e79c2fc3e3f3ff8fad66f0 326 Gene3D G3DSA:3.40.190.150 30 314 1.2E-111 T 14-10-2018 LH59_00160 632041a386e79c2fc3e3f3ff8fad66f0 326 Gene3D G3DSA:3.40.190.10 128 251 1.2E-111 T 14-10-2018 LH59_25890 55778b70c18fddff735dee2aa703f0d1 296 Gene3D G3DSA:3.40.190.290 93 294 3.1E-48 T 14-10-2018 LH59_25890 55778b70c18fddff735dee2aa703f0d1 296 Gene3D G3DSA:1.10.10.10 3 89 1.5E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_25890 55778b70c18fddff735dee2aa703f0d1 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 5.2E-20 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_25890 55778b70c18fddff735dee2aa703f0d1 296 SUPERFAMILY SSF53850 90 294 6.52E-45 T 14-10-2018 LH59_25890 55778b70c18fddff735dee2aa703f0d1 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 3.3E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_25890 55778b70c18fddff735dee2aa703f0d1 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 3.3E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_25890 55778b70c18fddff735dee2aa703f0d1 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 3.3E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_25890 55778b70c18fddff735dee2aa703f0d1 296 SUPERFAMILY SSF46785 4 114 2.05E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_25890 55778b70c18fddff735dee2aa703f0d1 296 Pfam PF03466 LysR substrate binding domain 91 292 1.7E-48 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_14155 49b2b9e45df6be5f7337100306d57111 274 Gene3D G3DSA:3.40.30.10 129 268 4.8E-32 T 14-10-2018 LH59_14155 49b2b9e45df6be5f7337100306d57111 274 ProSitePatterns PS00194 Thioredoxin family active site. 162 180 - T 14-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 LH59_14155 49b2b9e45df6be5f7337100306d57111 274 SUPERFAMILY SSF52833 107 266 9.45E-31 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_14155 49b2b9e45df6be5f7337100306d57111 274 Pfam PF08534 Redoxin 141 256 2.5E-15 T 14-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 LH59_09485 c49dc9d714c0eeddb702e144f2d67e7d 99 Pfam PF05154 TM2 domain 10 72 6.0E-14 T 14-10-2018 IPR007829 TM2 domain LH59_12825 ad96820275f03a67152378c49da15ccd 166 SUPERFAMILY SSF47240 14 166 2.46E-48 T 14-10-2018 IPR009078 Ferritin-like superfamily LH59_12825 ad96820275f03a67152378c49da15ccd 166 Gene3D G3DSA:1.20.1260.10 2 166 6.1E-58 T 14-10-2018 IPR012347 Ferritin-like LH59_12825 ad96820275f03a67152378c49da15ccd 166 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 48 64 2.5E-11 T 14-10-2018 IPR002177 DNA-binding protein Dps LH59_12825 ad96820275f03a67152378c49da15ccd 166 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 72 88 2.5E-11 T 14-10-2018 IPR002177 DNA-binding protein Dps LH59_12825 ad96820275f03a67152378c49da15ccd 166 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 143 161 2.5E-11 T 14-10-2018 IPR002177 DNA-binding protein Dps LH59_12825 ad96820275f03a67152378c49da15ccd 166 Pfam PF00210 Ferritin-like domain 30 166 1.9E-31 T 14-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 LH59_12825 ad96820275f03a67152378c49da15ccd 166 PIRSF PIRSF005900 5 166 1.1E-44 T 14-10-2018 IPR002177 DNA-binding protein Dps LH59_12825 ad96820275f03a67152378c49da15ccd 166 ProSitePatterns PS00819 Dps protein family signature 2. 74 88 - T 14-10-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 LH59_20495 1a8718a2535c8fee5fa35625f41ecfd3 125 Pfam PF11533 Protein of unknown function (DUF3225) 1 123 2.9E-62 T 14-10-2018 IPR024507 Protein of unknown function DUF3225 LH59_20495 1a8718a2535c8fee5fa35625f41ecfd3 125 SUPERFAMILY SSF54427 1 123 5.72E-37 T 14-10-2018 IPR032710 NTF2-like domain superfamily LH59_20495 1a8718a2535c8fee5fa35625f41ecfd3 125 Gene3D G3DSA:3.10.450.50 1 125 3.4E-50 T 14-10-2018 LH59_10450 2a1408b77ad093116faee727e13d4f72 837 Gene3D G3DSA:3.40.50.740 93 576 9.7E-230 T 14-10-2018 LH59_10450 2a1408b77ad093116faee727e13d4f72 837 SUPERFAMILY SSF53706 52 668 3.4E-165 T 14-10-2018 LH59_10450 2a1408b77ad093116faee727e13d4f72 837 Pfam PF01568 Molydopterin dinucleotide binding domain 684 804 3.1E-24 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 LH59_10450 2a1408b77ad093116faee727e13d4f72 837 Pfam PF00384 Molybdopterin oxidoreductase 93 568 7.2E-75 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_10450 2a1408b77ad093116faee727e13d4f72 837 SUPERFAMILY SSF50692 677 826 9.04E-43 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily LH59_10450 2a1408b77ad093116faee727e13d4f72 837 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 724 751 - T 14-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 LH59_10450 2a1408b77ad093116faee727e13d4f72 837 Gene3D G3DSA:2.40.40.20 657 821 4.4E-47 T 14-10-2018 LH59_10450 2a1408b77ad093116faee727e13d4f72 837 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 510 527 - T 14-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 LH59_10450 2a1408b77ad093116faee727e13d4f72 837 Gene3D G3DSA:3.90.55.10 49 623 9.7E-230 T 14-10-2018 LH59_10450 2a1408b77ad093116faee727e13d4f72 837 Gene3D G3DSA:3.40.228.10 186 649 9.7E-230 T 14-10-2018 LH59_22010 1d9e4dd423e2a9a139bd09b6433519fb 175 Pfam PF02627 Carboxymuconolactone decarboxylase family 39 121 5.7E-15 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 LH59_22010 1d9e4dd423e2a9a139bd09b6433519fb 175 SUPERFAMILY SSF69118 1 171 3.94E-44 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 LH59_22010 1d9e4dd423e2a9a139bd09b6433519fb 175 Gene3D G3DSA:1.20.1290.10 32 171 7.5E-49 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 LH59_17250 f3c755850c44679ef4e9bd2f13eca385 68 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 1.6E-29 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 LH59_17250 f3c755850c44679ef4e9bd2f13eca385 68 PRINTS PR00050 Cold shock protein signature 25 34 8.0E-15 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 LH59_17250 f3c755850c44679ef4e9bd2f13eca385 68 PRINTS PR00050 Cold shock protein signature 40 58 8.0E-15 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 LH59_17250 f3c755850c44679ef4e9bd2f13eca385 68 PRINTS PR00050 Cold shock protein signature 4 19 8.0E-15 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 LH59_17250 f3c755850c44679ef4e9bd2f13eca385 68 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 14-10-2018 IPR019844 Cold-shock conserved site LH59_17250 f3c755850c44679ef4e9bd2f13eca385 68 SMART SM00357 3 67 7.9E-28 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 LH59_17250 f3c755850c44679ef4e9bd2f13eca385 68 SUPERFAMILY SSF50249 1 66 1.37E-24 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_17250 f3c755850c44679ef4e9bd2f13eca385 68 PIRSF PIRSF002599 1 68 2.5E-25 T 14-10-2018 IPR012156 Cold shock, CspA GO:0003676 LH59_17250 f3c755850c44679ef4e9bd2f13eca385 68 Gene3D G3DSA:2.40.50.140 2 66 1.6E-28 T 14-10-2018 LH59_16260 6fd337e7455f66f32fc7b2dc4557f568 330 SUPERFAMILY SSF53850 117 287 7.93E-9 T 14-10-2018 LH59_16260 6fd337e7455f66f32fc7b2dc4557f568 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 326 8.9E-81 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_16260 6fd337e7455f66f32fc7b2dc4557f568 330 Gene3D G3DSA:3.40.190.10 132 255 6.1E-111 T 14-10-2018 LH59_16260 6fd337e7455f66f32fc7b2dc4557f568 330 PIRSF PIRSF017082 1 330 4.8E-77 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_16260 6fd337e7455f66f32fc7b2dc4557f568 330 Gene3D G3DSA:3.40.190.150 34 320 6.1E-111 T 14-10-2018 LH59_00190 b5eee65d106091773712ed8a4e64aba8 288 Gene3D G3DSA:1.10.3720.10 8 280 1.2E-57 T 14-10-2018 IPR035906 MetI-like superfamily LH59_00190 b5eee65d106091773712ed8a4e64aba8 288 SUPERFAMILY SSF161098 7 278 1.23E-55 T 14-10-2018 IPR035906 MetI-like superfamily LH59_00190 b5eee65d106091773712ed8a4e64aba8 288 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 16 278 2.1E-7 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_00895 3c7b56dd061d1ebcacf4931f16a14da9 258 SUPERFAMILY SSF102705 8 257 2.75E-71 T 14-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily LH59_00895 3c7b56dd061d1ebcacf4931f16a14da9 258 Gene3D G3DSA:3.40.1390.30 10 246 3.4E-74 T 14-10-2018 LH59_00895 3c7b56dd061d1ebcacf4931f16a14da9 258 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 10 257 1.6E-52 T 14-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 LH59_00895 3c7b56dd061d1ebcacf4931f16a14da9 258 Gene3D G3DSA:3.40.1390.30 100 229 3.4E-74 T 14-10-2018 LH59_00895 3c7b56dd061d1ebcacf4931f16a14da9 258 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 10 245 2.0E-50 T 14-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 LH59_05480 a39dbc8ef29936083ada78786f6f3fcd 132 Pfam PF01042 Endoribonuclease L-PSP 17 123 2.3E-26 T 14-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 LH59_05480 a39dbc8ef29936083ada78786f6f3fcd 132 Gene3D G3DSA:3.30.1330.40 14 129 3.0E-34 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 LH59_05480 a39dbc8ef29936083ada78786f6f3fcd 132 SUPERFAMILY SSF55298 15 124 3.14E-34 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 LH59_23270 6bacb9eac897706b61508af95588a811 348 Pfam PF03576 Peptidase family S58 30 340 1.1E-59 T 14-10-2018 IPR005321 Peptidase S58, DmpA LH59_23270 6bacb9eac897706b61508af95588a811 348 SUPERFAMILY SSF56266 29 343 1.57E-69 T 14-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 LH59_23270 6bacb9eac897706b61508af95588a811 348 Gene3D G3DSA:3.60.70.12 2 335 3.1E-111 T 14-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 LH59_14580 35c0fbcc2400d85f5990fdbe054d9627 390 Gene3D G3DSA:2.40.50.100 82 226 2.8E-82 T 14-10-2018 LH59_14580 35c0fbcc2400d85f5990fdbe054d9627 390 Pfam PF13533 Biotin-lipoyl like 85 131 7.9E-13 T 14-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain LH59_14580 35c0fbcc2400d85f5990fdbe054d9627 390 SUPERFAMILY SSF111369 74 310 3.92E-50 T 14-10-2018 LH59_14580 35c0fbcc2400d85f5990fdbe054d9627 390 Pfam PF13437 HlyD family secretion protein 194 295 3.3E-5 T 14-10-2018 LH59_14580 35c0fbcc2400d85f5990fdbe054d9627 390 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 58 386 2.1E-74 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 LH59_14580 35c0fbcc2400d85f5990fdbe054d9627 390 Gene3D G3DSA:1.10.287.470 117 190 2.8E-82 T 14-10-2018 LH59_14580 35c0fbcc2400d85f5990fdbe054d9627 390 Gene3D G3DSA:2.40.420.20 316 384 2.8E-82 T 14-10-2018 LH59_14580 35c0fbcc2400d85f5990fdbe054d9627 390 Gene3D G3DSA:2.40.30.170 71 315 2.8E-82 T 14-10-2018 LH59_21500 02e5036e287238b3631d5c04120bf887 170 Gene3D G3DSA:1.10.10.10 1 157 9.2E-36 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_21500 02e5036e287238b3631d5c04120bf887 170 SMART SM00347 43 146 9.6E-24 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_21500 02e5036e287238b3631d5c04120bf887 170 ProSitePatterns PS01117 MarR-type HTH domain signature. 85 119 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site LH59_21500 02e5036e287238b3631d5c04120bf887 170 Pfam PF01047 MarR family 52 111 1.1E-14 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_21500 02e5036e287238b3631d5c04120bf887 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 86 1.1E-12 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_21500 02e5036e287238b3631d5c04120bf887 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 136 156 1.1E-12 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_21500 02e5036e287238b3631d5c04120bf887 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 106 122 1.1E-12 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_21500 02e5036e287238b3631d5c04120bf887 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 102 1.1E-12 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_21500 02e5036e287238b3631d5c04120bf887 170 SUPERFAMILY SSF46785 11 157 5.96E-31 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_14800 2b011cbc549f2b98138bad935c8ba75d 267 SMART SM00382 31 221 3.9E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_14800 2b011cbc549f2b98138bad935c8ba75d 267 SUPERFAMILY SSF52540 2 224 8.71E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_14800 2b011cbc549f2b98138bad935c8ba75d 267 Gene3D G3DSA:3.40.50.300 1 233 1.1E-59 T 14-10-2018 LH59_14800 2b011cbc549f2b98138bad935c8ba75d 267 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_14800 2b011cbc549f2b98138bad935c8ba75d 267 Pfam PF00005 ABC transporter 22 162 1.6E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_17285 b56d47994e62375a807387c645830794 131 Gene3D G3DSA:3.30.1330.40 1 130 3.2E-37 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 LH59_17285 b56d47994e62375a807387c645830794 131 SUPERFAMILY SSF55298 3 129 1.21E-35 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 LH59_17285 b56d47994e62375a807387c645830794 131 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 104 122 - T 14-10-2018 IPR019897 RidA, conserved site Reactome: R-HSA-8849175 LH59_17285 b56d47994e62375a807387c645830794 131 Pfam PF01042 Endoribonuclease L-PSP 9 127 4.0E-29 T 14-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 LH59_05575 e0de1d1577fafdc5d5649b07f7d6c06d 756 Pfam PF07715 TonB-dependent Receptor Plug Domain 113 206 7.8E-12 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_05575 e0de1d1577fafdc5d5649b07f7d6c06d 756 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 114 756 1.4E-124 T 14-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 LH59_05575 e0de1d1577fafdc5d5649b07f7d6c06d 756 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 739 756 - T 14-10-2018 IPR010917 TonB-dependent receptor, conserved site LH59_05575 e0de1d1577fafdc5d5649b07f7d6c06d 756 SUPERFAMILY SSF56935 69 756 7.69E-102 T 14-10-2018 LH59_05575 e0de1d1577fafdc5d5649b07f7d6c06d 756 Gene3D G3DSA:2.40.170.20 226 756 8.1E-82 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_05575 e0de1d1577fafdc5d5649b07f7d6c06d 756 Gene3D G3DSA:2.170.130.10 104 225 1.6E-18 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily LH59_05575 e0de1d1577fafdc5d5649b07f7d6c06d 756 Pfam PF00593 TonB dependent receptor 325 754 3.7E-35 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_15435 6ee62f296d9ce758b87c9914d3d4625d 363 Pfam PF06996 Type VI secretion, TssG 16 343 3.3E-89 T 14-10-2018 IPR010732 Type VI secretion, TssG-like LH59_15435 6ee62f296d9ce758b87c9914d3d4625d 363 TIGRFAM TIGR03347 VI_chp_1: type VI secretion protein, VC_A0111 family 16 344 1.3E-96 T 14-10-2018 IPR010732 Type VI secretion, TssG-like LH59_03640 8780d11c5438803d3fa563b544f94b2c 167 Gene3D G3DSA:3.40.630.30 1 141 2.1E-17 T 14-10-2018 LH59_03640 8780d11c5438803d3fa563b544f94b2c 167 Pfam PF00583 Acetyltransferase (GNAT) family 26 137 2.5E-11 T 14-10-2018 IPR000182 GNAT domain LH59_03640 8780d11c5438803d3fa563b544f94b2c 167 SUPERFAMILY SSF55729 3 141 2.34E-18 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_04605 fb266e33472b56d3f8e810d5a59ae169 458 SMART SM00646 287 442 7.3E-58 T 14-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 LH59_04605 fb266e33472b56d3f8e810d5a59ae169 458 Pfam PF11741 AMIN domain 49 152 7.1E-24 T 14-10-2018 IPR021731 AMIN domain LH59_04605 fb266e33472b56d3f8e810d5a59ae169 458 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 227 442 6.8E-48 T 14-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 LH59_04605 fb266e33472b56d3f8e810d5a59ae169 458 Gene3D G3DSA:3.40.630.40 213 454 8.4E-80 T 14-10-2018 LH59_04605 fb266e33472b56d3f8e810d5a59ae169 458 SUPERFAMILY SSF53187 225 445 2.2E-53 T 14-10-2018 LH59_04605 fb266e33472b56d3f8e810d5a59ae169 458 Gene3D G3DSA:2.60.40.3500 38 155 5.5E-33 T 14-10-2018 LH59_21085 792de12ec755f5b1fbc7d10edefe9c61 496 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 285 296 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site LH59_21085 792de12ec755f5b1fbc7d10edefe9c61 496 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 309 320 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site LH59_21085 792de12ec755f5b1fbc7d10edefe9c61 496 Pfam PF13746 4Fe-4S dicluster domain 232 338 4.2E-43 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain LH59_21085 792de12ec755f5b1fbc7d10edefe9c61 496 Pfam PF12801 4Fe-4S binding domain 108 150 7.0E-12 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain LH59_21085 792de12ec755f5b1fbc7d10edefe9c61 496 Pfam PF11614 IG-like fold at C-terminal of FixG, putative oxidoreductase 373 495 3.2E-25 T 14-10-2018 IPR032879 FixG, C-terminal immunoglobulin-like domain LH59_21085 792de12ec755f5b1fbc7d10edefe9c61 496 SUPERFAMILY SSF54862 118 358 1.67E-33 T 14-10-2018 LH59_21085 792de12ec755f5b1fbc7d10edefe9c61 496 Gene3D G3DSA:2.60.40.10 374 494 4.1E-18 T 14-10-2018 IPR013783 Immunoglobulin-like fold LH59_21085 792de12ec755f5b1fbc7d10edefe9c61 496 TIGRFAM TIGR02745 ccoG_rdxA_fixG: cytochrome c oxidase accessory protein CcoG 54 482 1.8E-149 T 14-10-2018 IPR014116 Cytochrome c oxidase cbb3 type, accessory protein FixG GO:0016021|GO:0055114 LH59_12760 481346bfed2512565644fc17b271a1d6 232 Gene3D G3DSA:2.60.120.10 12 132 1.1E-56 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_12760 481346bfed2512565644fc17b271a1d6 232 Pfam PF02678 Pirin 9 119 4.5E-37 T 14-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 LH59_12760 481346bfed2512565644fc17b271a1d6 232 SUPERFAMILY SSF51182 1 231 3.32E-79 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_12760 481346bfed2512565644fc17b271a1d6 232 Gene3D G3DSA:2.60.120.10 133 232 8.2E-34 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_12760 481346bfed2512565644fc17b271a1d6 232 PIRSF PIRSF006232 1 230 3.1E-54 T 14-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 LH59_26375 0ebd5209381f629c746ce61329431f3a 140 SUPERFAMILY SSF52821 33 138 4.19E-32 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily LH59_26375 0ebd5209381f629c746ce61329431f3a 140 Gene3D G3DSA:3.40.250.10 38 139 2.8E-29 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily LH59_26375 0ebd5209381f629c746ce61329431f3a 140 SMART SM00450 40 135 6.0E-24 T 14-10-2018 IPR001763 Rhodanese-like domain LH59_26375 0ebd5209381f629c746ce61329431f3a 140 Pfam PF00581 Rhodanese-like domain 42 131 4.6E-18 T 14-10-2018 IPR001763 Rhodanese-like domain LH59_24515 9dc7c3373362000c4f1262a99198421e 299 Pfam PF06250 Protein of unknown function (DUF1016) 21 142 6.4E-41 T 14-10-2018 IPR009362 Protein of unknown function DUF1016 LH59_24515 9dc7c3373362000c4f1262a99198421e 299 Pfam PF06250 Protein of unknown function (DUF1016) 143 285 5.7E-62 T 14-10-2018 IPR009362 Protein of unknown function DUF1016 LH59_24515 9dc7c3373362000c4f1262a99198421e 299 Gene3D G3DSA:3.40.1350.10 146 264 3.8E-6 T 14-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 LH59_12430 42a2895d117cd4f2e15bc48838a2325f 249 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 16 242 1.9E-38 T 14-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 LH59_12430 42a2895d117cd4f2e15bc48838a2325f 249 Gene3D G3DSA:3.20.20.190 12 240 2.8E-76 T 14-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 LH59_12430 42a2895d117cd4f2e15bc48838a2325f 249 SUPERFAMILY SSF51695 12 246 2.88E-63 T 14-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 LH59_20115 330b54bf97459038f012e6d2ceebf6a4 406 SUPERFAMILY SSF142764 5 399 2.62E-82 T 14-10-2018 LH59_20115 330b54bf97459038f012e6d2ceebf6a4 406 Gene3D G3DSA:3.40.980.20 231 401 2.8E-16 T 14-10-2018 LH59_20115 330b54bf97459038f012e6d2ceebf6a4 406 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 237 392 1.4E-16 T 14-10-2018 IPR031475 Four-carbon acid sugar kinase, C-terminal domain LH59_20115 330b54bf97459038f012e6d2ceebf6a4 406 Pfam PF07005 Putative sugar-binding N-terminal domain 5 221 3.4E-48 T 14-10-2018 IPR010737 Four-carbon acid sugar kinase, N-terminal domain LH59_20115 330b54bf97459038f012e6d2ceebf6a4 406 Gene3D G3DSA:3.40.50.10840 2 230 2.1E-57 T 14-10-2018 IPR037051 Four-carbon acid sugar kinase, N-terminal domain superfamily LH59_26400 515c43f4fc7b0105de8078eed33ae8ce 156 Gene3D G3DSA:3.40.1280.10 1 156 1.9E-59 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal LH59_26400 515c43f4fc7b0105de8078eed33ae8ce 156 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 2 153 30.121 T 14-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 LH59_26400 515c43f4fc7b0105de8078eed33ae8ce 156 SUPERFAMILY SSF75217 1 153 1.31E-40 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases LH59_26400 515c43f4fc7b0105de8078eed33ae8ce 156 Pfam PF00588 SpoU rRNA Methylase family 2 143 3.5E-32 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 LH59_26400 515c43f4fc7b0105de8078eed33ae8ce 156 PIRSF PIRSF029256 1 156 9.7E-59 T 14-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 LH59_04020 d4d6b7059662dfb41fa0fe1358837a81 575 Pfam PF03717 Penicillin-binding Protein dimerisation domain 65 212 7.3E-22 T 14-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 LH59_04020 d4d6b7059662dfb41fa0fe1358837a81 575 SUPERFAMILY SSF56519 60 226 1.57E-45 T 14-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 LH59_04020 d4d6b7059662dfb41fa0fe1358837a81 575 Hamap MF_02080 Peptidoglycan D,D-transpeptidase FtsI [ftsI]. 16 563 41.779 T 14-10-2018 IPR037532 Peptidoglycan D,D-transpeptidase FtsI GO:0005887|GO:0008658|GO:0008955|GO:0009252|GO:0051301 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 LH59_04020 d4d6b7059662dfb41fa0fe1358837a81 575 SUPERFAMILY SSF56601 178 561 2.64E-82 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like LH59_04020 d4d6b7059662dfb41fa0fe1358837a81 575 Gene3D G3DSA:3.40.710.10 288 470 1.1E-104 T 14-10-2018 LH59_04020 d4d6b7059662dfb41fa0fe1358837a81 575 Pfam PF00905 Penicillin binding protein transpeptidase domain 253 547 9.0E-67 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 LH59_04020 d4d6b7059662dfb41fa0fe1358837a81 575 Gene3D G3DSA:3.30.450.330 228 551 1.1E-104 T 14-10-2018 LH59_04020 d4d6b7059662dfb41fa0fe1358837a81 575 Gene3D G3DSA:3.90.1310.30 57 227 5.3E-46 T 14-10-2018 LH59_22485 c8fe16bc188a8242e65a7898ca37598f 288 Pfam PF01551 Peptidase family M23 185 279 4.2E-29 T 14-10-2018 IPR016047 Peptidase M23 LH59_22485 c8fe16bc188a8242e65a7898ca37598f 288 Gene3D G3DSA:2.70.70.10 129 288 5.1E-57 T 14-10-2018 IPR011055 Duplicated hybrid motif LH59_22485 c8fe16bc188a8242e65a7898ca37598f 288 Gene3D G3DSA:2.60.40.1590 29 128 2.7E-35 T 14-10-2018 LH59_22485 c8fe16bc188a8242e65a7898ca37598f 288 SUPERFAMILY SSF51261 150 283 5.23E-49 T 14-10-2018 IPR011055 Duplicated hybrid motif LH59_01945 cc6b633759fb7b35874e839cff0ab0de 253 Pfam PF01177 Asp/Glu/Hydantoin racemase 10 229 1.6E-7 T 14-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 LH59_01945 cc6b633759fb7b35874e839cff0ab0de 253 Gene3D G3DSA:3.40.50.12500 7 253 4.1E-85 T 14-10-2018 LH59_01945 cc6b633759fb7b35874e839cff0ab0de 253 Hamap MF_00943 Maleate isomerase [maiA]. 8 253 50.738 T 14-10-2018 IPR028615 Maleate isomerase GO:0050076 KEGG: 00650+5.2.1.1|KEGG: 00760+5.2.1.1|MetaCyc: PWY-5033|MetaCyc: PWY-6993|MetaCyc: PWY-7128|MetaCyc: PWY-722 LH59_01945 cc6b633759fb7b35874e839cff0ab0de 253 PIRSF PIRSF015736 1 253 2.6E-60 T 14-10-2018 IPR026286 Maleate isomerase/Arylmalonate decarboxylase LH59_25290 2adffac63a9719ab33a2aad197087f0d 202 Gene3D G3DSA:1.10.357.10 1 200 6.3E-49 T 14-10-2018 LH59_25290 2adffac63a9719ab33a2aad197087f0d 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 2.3E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_25290 2adffac63a9719ab33a2aad197087f0d 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 2.3E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_25290 2adffac63a9719ab33a2aad197087f0d 202 SUPERFAMILY SSF46689 14 87 2.82E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_25290 2adffac63a9719ab33a2aad197087f0d 202 SUPERFAMILY SSF48498 96 176 3.78E-10 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily LH59_25290 2adffac63a9719ab33a2aad197087f0d 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 64 4.4E-12 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_02365 c352085211e58918b62f097ae0bd25c5 391 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 9 387 2.1E-127 T 14-10-2018 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 LH59_27040 cf9a152209ae15257254cf62a39493b7 287 Gene3D G3DSA:3.60.20.10 2 233 1.3E-25 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal LH59_27040 cf9a152209ae15257254cf62a39493b7 287 PIRSF PIRSF009120 1 247 6.6E-113 T 14-10-2018 IPR016545 Uncharacterised conserved protein UCP009120, proteasome-type protease, Sll0069 LH59_27040 cf9a152209ae15257254cf62a39493b7 287 Pfam PF00227 Proteasome subunit 87 183 6.0E-6 T 14-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 LH59_27040 cf9a152209ae15257254cf62a39493b7 287 SUPERFAMILY SSF56235 2 240 1.05E-34 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal LH59_04910 185eef94ef743d5ef4dc2d840e845547 331 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_04910 185eef94ef743d5ef4dc2d840e845547 331 SMART SM00382 46 238 1.5E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_04910 185eef94ef743d5ef4dc2d840e845547 331 SUPERFAMILY SSF52540 28 260 3.22E-74 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_04910 185eef94ef743d5ef4dc2d840e845547 331 Gene3D G3DSA:3.40.50.300 28 330 3.8E-100 T 14-10-2018 LH59_04910 185eef94ef743d5ef4dc2d840e845547 331 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 239 322 5.5E-27 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_04910 185eef94ef743d5ef4dc2d840e845547 331 Pfam PF00005 ABC transporter 38 189 3.8E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_04910 185eef94ef743d5ef4dc2d840e845547 331 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 240 304 7.9E-20 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_13595 fb88130f909711708a2f88d21395b299 284 Pfam PF13847 Methyltransferase domain 84 206 3.0E-9 T 14-10-2018 IPR025714 Methyltransferase domain LH59_13595 fb88130f909711708a2f88d21395b299 284 SUPERFAMILY SSF53335 60 188 5.33E-26 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_13595 fb88130f909711708a2f88d21395b299 284 Gene3D G3DSA:3.40.50.150 59 217 2.0E-42 T 14-10-2018 LH59_14870 3b7f90f2a1692e2e7f4551399b807321 558 SUPERFAMILY SSF51556 71 514 1.04E-26 T 14-10-2018 IPR032466 Metal-dependent hydrolase LH59_14870 3b7f90f2a1692e2e7f4551399b807321 558 SUPERFAMILY SSF51338 23 555 3.17E-13 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 LH59_14870 3b7f90f2a1692e2e7f4551399b807321 558 Gene3D G3DSA:3.20.20.140 72 513 9.7E-104 T 14-10-2018 LH59_14870 3b7f90f2a1692e2e7f4551399b807321 558 Gene3D G3DSA:2.30.40.10 23 531 9.7E-104 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 LH59_14870 3b7f90f2a1692e2e7f4551399b807321 558 Pfam PF07969 Amidohydrolase family 68 553 5.5E-73 T 14-10-2018 IPR013108 Amidohydrolase 3 LH59_14870 3b7f90f2a1692e2e7f4551399b807321 558 Gene3D G3DSA:3.10.310.70 91 220 9.7E-104 T 14-10-2018 LH59_11430 77c28fb3736167b853a58537cda688fd 378 Pfam PF02119 Flagellar P-ring protein 34 377 1.1E-137 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 LH59_11430 77c28fb3736167b853a58537cda688fd 378 PRINTS PR01010 Flagellar P-ring protein signature 34 49 3.2E-85 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 LH59_11430 77c28fb3736167b853a58537cda688fd 378 PRINTS PR01010 Flagellar P-ring protein signature 134 152 3.2E-85 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 LH59_11430 77c28fb3736167b853a58537cda688fd 378 PRINTS PR01010 Flagellar P-ring protein signature 95 114 3.2E-85 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 LH59_11430 77c28fb3736167b853a58537cda688fd 378 PRINTS PR01010 Flagellar P-ring protein signature 117 134 3.2E-85 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 LH59_11430 77c28fb3736167b853a58537cda688fd 378 PRINTS PR01010 Flagellar P-ring protein signature 49 64 3.2E-85 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 LH59_11430 77c28fb3736167b853a58537cda688fd 378 PRINTS PR01010 Flagellar P-ring protein signature 264 276 3.2E-85 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 LH59_11430 77c28fb3736167b853a58537cda688fd 378 PRINTS PR01010 Flagellar P-ring protein signature 200 218 3.2E-85 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 LH59_11430 77c28fb3736167b853a58537cda688fd 378 PRINTS PR01010 Flagellar P-ring protein signature 69 84 3.2E-85 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 LH59_11430 77c28fb3736167b853a58537cda688fd 378 PRINTS PR01010 Flagellar P-ring protein signature 174 192 3.2E-85 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 LH59_11430 77c28fb3736167b853a58537cda688fd 378 Hamap MF_00416 Flagellar P-ring protein [flgI]. 14 378 38.313 T 14-10-2018 IPR001782 Flagellar P-ring protein GO:0005198|GO:0009428|GO:0030288|GO:0071973 LH59_03200 600d92ca16cc2715a19d7d8f40a240f7 167 Pfam PF05433 Glycine zipper 2TM domain 76 115 1.0E-8 T 14-10-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 LH59_09625 9faf4dc85b9feb247e488d9dd64d96b1 133 Pfam PF03610 PTS system fructose IIA component 4 116 3.6E-16 T 14-10-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 LH59_09625 9faf4dc85b9feb247e488d9dd64d96b1 133 SUPERFAMILY SSF53062 1 132 7.72E-25 T 14-10-2018 IPR036662 Phosphotransferase system, mannose-type IIA component superfamily GO:0009401|GO:0016021 LH59_09625 9faf4dc85b9feb247e488d9dd64d96b1 133 Gene3D G3DSA:3.40.50.510 2 133 5.9E-27 T 14-10-2018 IPR036662 Phosphotransferase system, mannose-type IIA component superfamily GO:0009401|GO:0016021 LH59_00025 fbce1a20529a67e6afa32ff119697ae7 228 Gene3D G3DSA:3.40.50.850 5 208 2.5E-46 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 LH59_00025 fbce1a20529a67e6afa32ff119697ae7 228 SUPERFAMILY SSF52499 5 207 8.5E-45 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 LH59_00025 fbce1a20529a67e6afa32ff119697ae7 228 Pfam PF00857 Isochorismatase family 16 169 7.0E-28 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 LH59_16020 07bd87bd60c962ed8c7be9e7f060aa03 320 SMART SM00829 10 316 2.3E-40 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 LH59_16020 07bd87bd60c962ed8c7be9e7f060aa03 320 SUPERFAMILY SSF50129 1 148 8.22E-40 T 14-10-2018 IPR011032 GroES-like superfamily LH59_16020 07bd87bd60c962ed8c7be9e7f060aa03 320 Gene3D G3DSA:3.90.180.10 8 314 4.7E-99 T 14-10-2018 LH59_16020 07bd87bd60c962ed8c7be9e7f060aa03 320 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 99 1.6E-11 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 LH59_16020 07bd87bd60c962ed8c7be9e7f060aa03 320 SUPERFAMILY SSF51735 116 285 1.47E-44 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_16020 07bd87bd60c962ed8c7be9e7f060aa03 320 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 144 165 - T 14-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 LH59_16020 07bd87bd60c962ed8c7be9e7f060aa03 320 Pfam PF13602 Zinc-binding dehydrogenase 186 315 1.8E-27 T 14-10-2018 LH59_16020 07bd87bd60c962ed8c7be9e7f060aa03 320 Gene3D G3DSA:3.40.50.720 124 284 4.7E-99 T 14-10-2018 LH59_05690 30c609033dc044f23b318fe87908bba4 307 Gene3D G3DSA:3.60.110.10 1 281 2.5E-93 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily LH59_05690 30c609033dc044f23b318fe87908bba4 307 SUPERFAMILY SSF56317 1 295 1.07E-70 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily LH59_05690 30c609033dc044f23b318fe87908bba4 307 ProSitePatterns PS00921 Nitrilases / cyanide hydratase active site signature. 161 174 - T 14-10-2018 IPR000132 Nitrilase/cyanide hydratase, conserved site GO:0016810 LH59_05690 30c609033dc044f23b318fe87908bba4 307 Pfam PF00795 Carbon-nitrogen hydrolase 5 277 1.1E-52 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 LH59_08790 98d70b2d38eba6774c9521d80a2286cb 490 Pfam PF02743 Cache domain 87 265 6.5E-15 T 14-10-2018 IPR033479 Double Cache domain 1 LH59_08790 98d70b2d38eba6774c9521d80a2286cb 490 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 320 487 1.9E-52 T 14-10-2018 IPR000160 GGDEF domain LH59_08790 98d70b2d38eba6774c9521d80a2286cb 490 Gene3D G3DSA:3.30.70.270 314 488 3.6E-58 T 14-10-2018 LH59_08790 98d70b2d38eba6774c9521d80a2286cb 490 Gene3D G3DSA:3.30.450.20 185 273 6.7E-16 T 14-10-2018 LH59_08790 98d70b2d38eba6774c9521d80a2286cb 490 SUPERFAMILY SSF55073 329 487 1.57E-46 T 14-10-2018 IPR029787 Nucleotide cyclase LH59_08790 98d70b2d38eba6774c9521d80a2286cb 490 Gene3D G3DSA:3.30.450.20 30 182 5.7E-34 T 14-10-2018 LH59_08790 98d70b2d38eba6774c9521d80a2286cb 490 SMART SM00267 313 488 2.3E-64 T 14-10-2018 IPR000160 GGDEF domain LH59_08790 98d70b2d38eba6774c9521d80a2286cb 490 Pfam PF00990 Diguanylate cyclase, GGDEF domain 324 484 1.2E-48 T 14-10-2018 IPR000160 GGDEF domain LH59_20585 9dfa526e09bfa0908c36860b18daf04f 397 Gene3D G3DSA:2.60.120.650 1 210 2.1E-75 T 14-10-2018 LH59_20585 9dfa526e09bfa0908c36860b18daf04f 397 SUPERFAMILY SSF51197 6 300 5.63E-63 T 14-10-2018 LH59_20585 9dfa526e09bfa0908c36860b18daf04f 397 Pfam PF08007 Cupin superfamily protein 15 325 1.0E-86 T 14-10-2018 IPR003347 JmjC domain LH59_20585 9dfa526e09bfa0908c36860b18daf04f 397 Gene3D G3DSA:1.10.10.2510 246 395 1.3E-14 T 14-10-2018 LH59_20585 9dfa526e09bfa0908c36860b18daf04f 397 SMART SM00558 98 225 0.0023 T 14-10-2018 IPR003347 JmjC domain LH59_27420 eef9dff400e6d4646fa61c553ad662bf 467 Gene3D G3DSA:3.20.20.370 200 419 6.9E-19 T 14-10-2018 LH59_19405 b5a4b982e0719d0f5700beebdbb567c8 585 SUPERFAMILY SSF51445 83 495 1.95E-101 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily LH59_19405 b5a4b982e0719d0f5700beebdbb567c8 585 Gene3D G3DSA:3.20.20.80 94 494 2.0E-160 T 14-10-2018 LH59_19405 b5a4b982e0719d0f5700beebdbb567c8 585 Pfam PF11941 Domain of unknown function (DUF3459) 485 572 1.0E-14 T 14-10-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) LH59_19405 b5a4b982e0719d0f5700beebdbb567c8 585 PIRSF PIRSF006337 2 573 7.9E-211 T 14-10-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|MetaCyc: PWY-2661 LH59_19405 b5a4b982e0719d0f5700beebdbb567c8 585 Gene3D G3DSA:1.10.10.760 423 467 2.0E-160 T 14-10-2018 LH59_19405 b5a4b982e0719d0f5700beebdbb567c8 585 Pfam PF00128 Alpha amylase, catalytic domain 113 196 8.1E-12 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 LH59_19405 b5a4b982e0719d0f5700beebdbb567c8 585 SUPERFAMILY SSF81296 5 82 2.6E-11 T 14-10-2018 IPR014756 Immunoglobulin E-set LH59_19405 b5a4b982e0719d0f5700beebdbb567c8 585 TIGRFAM TIGR02402 trehalose_TreZ: malto-oligosyltrehalose trehalohydrolase 8 539 7.3E-202 T 14-10-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|MetaCyc: PWY-2661 LH59_19405 b5a4b982e0719d0f5700beebdbb567c8 585 SMART SM00642 101 438 5.9E-11 T 14-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 LH59_19405 b5a4b982e0719d0f5700beebdbb567c8 585 Gene3D G3DSA:2.60.40.10 3 83 6.6E-18 T 14-10-2018 IPR013783 Immunoglobulin-like fold LH59_15080 92b49811dd45b03e0d058b72dd89f78a 135 Gene3D G3DSA:1.20.1290.10 1 135 7.8E-58 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 LH59_15080 92b49811dd45b03e0d058b72dd89f78a 135 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 64 110 2.3E-16 T 14-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 LH59_15080 92b49811dd45b03e0d058b72dd89f78a 135 Pfam PF02627 Carboxymuconolactone decarboxylase family 46 126 4.9E-22 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 LH59_15080 92b49811dd45b03e0d058b72dd89f78a 135 SUPERFAMILY SSF69118 16 132 1.7E-34 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 LH59_23095 98078f598c13ff1618584a13808b4166 543 Pfam PF02653 Branched-chain amino acid transport system / permease component 250 527 2.9E-51 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_23095 98078f598c13ff1618584a13808b4166 543 Gene3D G3DSA:1.25.10.10 108 246 4.1E-7 T 14-10-2018 IPR011989 Armadillo-like helical LH59_23095 98078f598c13ff1618584a13808b4166 543 SMART SM00567 E-Z type HEAT repeats 135 164 0.1 T 14-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 LH59_23095 98078f598c13ff1618584a13808b4166 543 SMART SM00567 E-Z type HEAT repeats 225 255 530.0 T 14-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 LH59_23095 98078f598c13ff1618584a13808b4166 543 SMART SM00567 E-Z type HEAT repeats 187 216 110.0 T 14-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 LH59_23095 98078f598c13ff1618584a13808b4166 543 SMART SM00567 E-Z type HEAT repeats 46 74 290.0 T 14-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 LH59_23095 98078f598c13ff1618584a13808b4166 543 SUPERFAMILY SSF48371 130 238 5.54E-10 T 14-10-2018 IPR016024 Armadillo-type fold LH59_23095 98078f598c13ff1618584a13808b4166 543 TIGRFAM TIGR03409 urea_trans_UrtB: urea ABC transporter, permease protein UrtB 250 540 5.0E-129 T 14-10-2018 IPR017779 ABC transporter, urea permease protein UrtB, bacterial-type LH59_26090 d269700e0c20483c746ec4492c5e2032 501 Gene3D G3DSA:3.30.300.310 398 500 5.9E-27 T 14-10-2018 LH59_26090 d269700e0c20483c746ec4492c5e2032 501 Pfam PF13193 AMP-binding enzyme C-terminal domain 412 486 3.5E-18 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain LH59_26090 d269700e0c20483c746ec4492c5e2032 501 ProSitePatterns PS00455 Putative AMP-binding domain signature. 156 167 - T 14-10-2018 IPR020845 AMP-binding, conserved site LH59_26090 d269700e0c20483c746ec4492c5e2032 501 Gene3D G3DSA:3.40.50.12780 2 395 3.7E-93 T 14-10-2018 LH59_26090 d269700e0c20483c746ec4492c5e2032 501 Pfam PF00501 AMP-binding enzyme 7 402 3.4E-83 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 LH59_26090 d269700e0c20483c746ec4492c5e2032 501 SUPERFAMILY SSF56801 4 497 2.35E-131 T 14-10-2018 LH59_21280 4e56d736db2ea09ef641e0551b6e2d0f 128 Pfam PF03994 Domain of Unknown Function (DUF350) 75 127 2.1E-8 T 14-10-2018 IPR007140 Protein of unknown function DUF350 LH59_21280 4e56d736db2ea09ef641e0551b6e2d0f 128 Pfam PF03994 Domain of Unknown Function (DUF350) 10 63 8.9E-11 T 14-10-2018 IPR007140 Protein of unknown function DUF350 LH59_17800 d35665c0456bec976167361d9057ec3f 429 Pfam PF01566 Natural resistance-associated macrophage protein 45 401 1.3E-95 T 14-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 LH59_17800 d35665c0456bec976167361d9057ec3f 429 PRINTS PR00447 Natural resistance-associated macrophage protein signature 104 130 2.6E-38 T 14-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 LH59_17800 d35665c0456bec976167361d9057ec3f 429 PRINTS PR00447 Natural resistance-associated macrophage protein signature 372 391 2.6E-38 T 14-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 LH59_17800 d35665c0456bec976167361d9057ec3f 429 PRINTS PR00447 Natural resistance-associated macrophage protein signature 132 151 2.6E-38 T 14-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 LH59_17800 d35665c0456bec976167361d9057ec3f 429 PRINTS PR00447 Natural resistance-associated macrophage protein signature 157 178 2.6E-38 T 14-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 LH59_17800 d35665c0456bec976167361d9057ec3f 429 PRINTS PR00447 Natural resistance-associated macrophage protein signature 209 232 2.6E-38 T 14-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 LH59_17800 d35665c0456bec976167361d9057ec3f 429 PRINTS PR00447 Natural resistance-associated macrophage protein signature 311 330 2.6E-38 T 14-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 LH59_03205 4a6b4e08aac11b1bbba5c0aa5176eeb3 79 Pfam PF00550 Phosphopantetheine attachment site 22 74 1.8E-8 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain LH59_03205 4a6b4e08aac11b1bbba5c0aa5176eeb3 79 SUPERFAMILY SSF47336 6 78 9.29E-11 T 14-10-2018 IPR036736 ACP-like superfamily LH59_03205 4a6b4e08aac11b1bbba5c0aa5176eeb3 79 Gene3D G3DSA:1.10.1200.10 3 78 7.6E-15 T 14-10-2018 IPR036736 ACP-like superfamily LH59_26225 694dac7c5f0550e51625c31f3333e014 212 SMART SM01007 9 187 9.6E-48 T 14-10-2018 IPR001303 Class II aldolase/adducin N-terminal LH59_26225 694dac7c5f0550e51625c31f3333e014 212 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 9 186 1.2E-42 T 14-10-2018 IPR001303 Class II aldolase/adducin N-terminal LH59_26225 694dac7c5f0550e51625c31f3333e014 212 Gene3D G3DSA:3.40.225.10 4 211 3.0E-52 T 14-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily LH59_26225 694dac7c5f0550e51625c31f3333e014 212 SUPERFAMILY SSF53639 4 209 9.61E-53 T 14-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily LH59_11995 29bb4de22e34137823a914d3edfcc2c3 124 Pfam PF01124 MAPEG family 4 121 2.5E-21 T 14-10-2018 IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein LH59_11995 29bb4de22e34137823a914d3edfcc2c3 124 Gene3D G3DSA:1.20.120.550 2 124 3.5E-17 T 14-10-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain superfamily LH59_11995 29bb4de22e34137823a914d3edfcc2c3 124 SUPERFAMILY SSF161084 4 120 1.1E-22 T 14-10-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain superfamily LH59_19510 53816ea34c7df62760860b4f3e3c3795 257 Gene3D G3DSA:3.40.50.1820 29 255 3.0E-38 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_19510 53816ea34c7df62760860b4f3e3c3795 257 Pfam PF12697 Alpha/beta hydrolase family 35 247 1.3E-17 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_19510 53816ea34c7df62760860b4f3e3c3795 257 SUPERFAMILY SSF53474 29 253 1.83E-28 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_22050 7178a39c56011aeb586269cdd75aa1a8 429 Gene3D G3DSA:3.40.50.10540 4 408 9.4E-127 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily LH59_22050 7178a39c56011aeb586269cdd75aa1a8 429 Pfam PF02515 CoA-transferase family III 4 391 1.6E-114 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 LH59_22050 7178a39c56011aeb586269cdd75aa1a8 429 SUPERFAMILY SSF89796 2 414 5.1E-123 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily LH59_22050 7178a39c56011aeb586269cdd75aa1a8 429 Gene3D G3DSA:3.30.1540.10 245 343 9.4E-127 T 14-10-2018 LH59_03155 1957fe6050c966f5319c55bf46712489 200 Pfam PF05728 Uncharacterised protein family (UPF0227) 1 191 1.5E-49 T 14-10-2018 IPR008886 Uncharacterised protein family UPF0227/Esterase YqiA LH59_03155 1957fe6050c966f5319c55bf46712489 200 Gene3D G3DSA:3.40.50.1820 1 193 1.1E-53 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_03155 1957fe6050c966f5319c55bf46712489 200 SUPERFAMILY SSF53474 2 190 1.97E-16 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_05950 376e88074b5279d65c6061315c1ed2fc 287 SUPERFAMILY SSF53474 30 268 3.71E-17 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_05950 376e88074b5279d65c6061315c1ed2fc 287 Gene3D G3DSA:3.40.50.1820 15 286 2.1E-54 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_13400 fc568d579f1c0cda7d04e111e6dd4292 327 Pfam PF16344 Domain of unknown function (DUF4974) 227 311 3.6E-9 T 14-10-2018 IPR032508 Protein FecR, C-terminal LH59_13400 fc568d579f1c0cda7d04e111e6dd4292 327 Pfam PF04773 FecR protein 124 216 1.8E-12 T 14-10-2018 IPR006860 FecR protein LH59_13400 fc568d579f1c0cda7d04e111e6dd4292 327 Pfam PF16220 Domain of unknown function (DUF4880) 17 58 1.1E-5 T 14-10-2018 IPR032623 FecR, N-terminal LH59_13400 fc568d579f1c0cda7d04e111e6dd4292 327 Gene3D G3DSA:3.55.50.30 253 326 6.8E-8 T 14-10-2018 LH59_13400 fc568d579f1c0cda7d04e111e6dd4292 327 PIRSF PIRSF018266 6 327 3.6E-64 T 14-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component LH59_13400 fc568d579f1c0cda7d04e111e6dd4292 327 Gene3D G3DSA:2.60.120.1440 116 251 6.7E-10 T 14-10-2018 LH59_08385 ef1e1e0a364f012ee3722953da06f795 525 SUPERFAMILY SSF55073 370 522 2.04E-45 T 14-10-2018 IPR029787 Nucleotide cyclase LH59_08385 ef1e1e0a364f012ee3722953da06f795 525 Gene3D G3DSA:3.30.70.270 359 523 7.5E-53 T 14-10-2018 LH59_08385 ef1e1e0a364f012ee3722953da06f795 525 Pfam PF00990 Diguanylate cyclase, GGDEF domain 365 518 2.5E-41 T 14-10-2018 IPR000160 GGDEF domain LH59_08385 ef1e1e0a364f012ee3722953da06f795 525 SMART SM00267 351 523 7.2E-54 T 14-10-2018 IPR000160 GGDEF domain LH59_08385 ef1e1e0a364f012ee3722953da06f795 525 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 362 521 2.5E-44 T 14-10-2018 IPR000160 GGDEF domain LH59_03315 9d7867d4f1668c1ecf728fd7ce32ea10 351 Gene3D G3DSA:3.40.190.10 47 146 6.1E-13 T 14-10-2018 LH59_03315 9d7867d4f1668c1ecf728fd7ce32ea10 351 SUPERFAMILY SSF53850 58 302 3.23E-28 T 14-10-2018 LH59_03315 9d7867d4f1668c1ecf728fd7ce32ea10 351 Gene3D G3DSA:3.40.190.10 160 350 8.5E-25 T 14-10-2018 LH59_03315 9d7867d4f1668c1ecf728fd7ce32ea10 351 Pfam PF09084 NMT1/THI5 like 64 274 5.5E-18 T 14-10-2018 IPR015168 SsuA/THI5-like LH59_10035 127e9341098a0e4fdc4095ca9a428026 247 Pfam PF13723 Beta-ketoacyl synthase, N-terminal domain 22 243 1.7E-73 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal LH59_11775 e858dd59803761c7aedcfa3a8846d615 115 SUPERFAMILY SSF54285 10 84 1.18E-21 T 14-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp LH59_11775 e858dd59803761c7aedcfa3a8846d615 115 Pfam PF03658 RnfH family Ubiquitin 11 93 1.7E-28 T 14-10-2018 IPR005346 RnfH protein LH59_11775 e858dd59803761c7aedcfa3a8846d615 115 Gene3D G3DSA:3.10.20.280 2 95 6.8E-30 T 14-10-2018 IPR037021 RnfH superfamily LH59_11775 e858dd59803761c7aedcfa3a8846d615 115 Hamap MF_00460 Protein RnfH [rnfH]. 11 101 22.647 T 14-10-2018 IPR005346 RnfH protein LH59_23105 2a14e8b87177e2755f3383286aaa8c3f 279 Pfam PF00005 ABC transporter 52 207 6.2E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_23105 2a14e8b87177e2755f3383286aaa8c3f 279 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 257 278 5.3E-9 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal LH59_23105 2a14e8b87177e2755f3383286aaa8c3f 279 TIGRFAM TIGR03411 urea_trans_UrtD: urea ABC transporter, ATP-binding protein UrtD 36 279 4.0E-115 T 14-10-2018 IPR017781 ABC transporter, urea, ATP-binding protein, UrtD LH59_23105 2a14e8b87177e2755f3383286aaa8c3f 279 Gene3D G3DSA:3.40.50.300 33 279 5.0E-48 T 14-10-2018 LH59_23105 2a14e8b87177e2755f3383286aaa8c3f 279 SUPERFAMILY SSF52540 36 277 3.26E-49 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_02470 d161873058605a279c114fa4af592339 228 SMART SM00448 1 111 5.4E-39 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_02470 d161873058605a279c114fa4af592339 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 144 219 5.3E-27 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_02470 d161873058605a279c114fa4af592339 228 Pfam PF00072 Response regulator receiver domain 3 112 6.4E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_02470 d161873058605a279c114fa4af592339 228 SUPERFAMILY SSF52172 1 177 4.98E-40 T 14-10-2018 IPR011006 CheY-like superfamily LH59_02470 d161873058605a279c114fa4af592339 228 TIGRFAM TIGR01387 cztR_silR_copR: heavy metal response regulator 3 219 1.4E-100 T 14-10-2018 IPR006291 Transcriptional regulatory protein PcoR, heavy metal response GO:0003677|GO:0006355 LH59_02470 d161873058605a279c114fa4af592339 228 Gene3D G3DSA:1.10.10.10 122 226 3.3E-33 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_02470 d161873058605a279c114fa4af592339 228 Gene3D G3DSA:3.40.50.2300 1 120 4.5E-38 T 14-10-2018 LH59_02470 d161873058605a279c114fa4af592339 228 SMART SM00862 144 219 1.6E-27 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_15540 84f9a49673601ad9f85fedc3a0395d3d 1236 Pfam PF06744 Type VI secretion protein IcmF C-terminal 959 1159 1.4E-52 T 14-10-2018 IPR010623 Type VI secretion system IcmF, C-terminal LH59_15540 84f9a49673601ad9f85fedc3a0395d3d 1236 Pfam PF14331 ImcF-related N-terminal domain 170 422 2.1E-80 T 14-10-2018 IPR025743 ImcF-related, N-terminal domain LH59_15540 84f9a49673601ad9f85fedc3a0395d3d 1236 SUPERFAMILY SSF52540 101 294 1.17E-8 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_15540 84f9a49673601ad9f85fedc3a0395d3d 1236 Pfam PF06761 Intracellular multiplication and human macrophage-killing 474 822 3.0E-91 T 14-10-2018 IPR009612 ImcF-related LH59_15540 84f9a49673601ad9f85fedc3a0395d3d 1236 TIGRFAM TIGR03348 VI_IcmF: type VI secretion protein IcmF 14 1188 5.2E-217 T 14-10-2018 IPR017731 Type VI secretion system, IcmF LH59_12700 a6ea8ec929cc5d4e59414b69d2324e52 309 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 309 2.0E-63 T 14-10-2018 IPR005229 Conserved hypothetical protein CHP00255 LH59_12700 a6ea8ec929cc5d4e59414b69d2324e52 309 Pfam PF03755 YicC-like family, N-terminal region 2 153 3.9E-36 T 14-10-2018 IPR013527 YicC-like, N-terminal LH59_12700 a6ea8ec929cc5d4e59414b69d2324e52 309 Pfam PF08340 Domain of unknown function (DUF1732) 215 309 1.5E-33 T 14-10-2018 IPR013551 Domain of unknown function DUF1732 LH59_06245 3b6c6ffd46ea3a14fea32bf8bf6578c5 1178 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1166 0.0 T 14-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 LH59_06245 3b6c6ffd46ea3a14fea32bf8bf6578c5 1178 Gene3D G3DSA:3.40.50.300 1014 1177 5.1E-46 T 14-10-2018 LH59_06245 3b6c6ffd46ea3a14fea32bf8bf6578c5 1178 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1168 22.228 T 14-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 LH59_06245 3b6c6ffd46ea3a14fea32bf8bf6578c5 1178 SUPERFAMILY SSF57997 272 496 9.81E-5 T 14-10-2018 LH59_06245 3b6c6ffd46ea3a14fea32bf8bf6578c5 1178 SMART SM00968 518 626 1.2E-7 T 14-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 LH59_06245 3b6c6ffd46ea3a14fea32bf8bf6578c5 1178 SUPERFAMILY SSF75553 519 674 8.76E-9 T 14-10-2018 IPR036277 SMCs flexible hinge superfamily GO:0005515|GO:0005524|GO:0005694|GO:0051276 LH59_06245 3b6c6ffd46ea3a14fea32bf8bf6578c5 1178 PIRSF PIRSF005719 1 1174 2.9E-247 T 14-10-2018 IPR024704 Structural maintenance of chromosomes protein LH59_06245 3b6c6ffd46ea3a14fea32bf8bf6578c5 1178 SUPERFAMILY SSF52540 2 1168 1.68E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_06245 3b6c6ffd46ea3a14fea32bf8bf6578c5 1178 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1159 7.6E-64 T 14-10-2018 IPR003395 RecF/RecN/SMC, N-terminal LH59_06245 3b6c6ffd46ea3a14fea32bf8bf6578c5 1178 Gene3D G3DSA:3.40.50.300 1 232 3.5E-49 T 14-10-2018 LH59_13815 84816ed495fe256de32bd479bbc75461 196 Pfam PF04264 YceI-like domain 28 190 3.1E-30 T 14-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like LH59_13815 84816ed495fe256de32bd479bbc75461 196 Gene3D G3DSA:2.40.128.110 26 193 4.3E-40 T 14-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily LH59_13815 84816ed495fe256de32bd479bbc75461 196 SUPERFAMILY SSF101874 26 191 2.22E-42 T 14-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily LH59_13815 84816ed495fe256de32bd479bbc75461 196 SMART SM00867 27 191 2.8E-48 T 14-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like LH59_04690 b3789da00de923b9f88aa186d53d9ae5 301 Pfam PF03466 LysR substrate binding domain 90 294 2.3E-40 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_04690 b3789da00de923b9f88aa186d53d9ae5 301 Gene3D G3DSA:3.40.190.290 91 294 1.7E-58 T 14-10-2018 LH59_04690 b3789da00de923b9f88aa186d53d9ae5 301 SUPERFAMILY SSF46785 5 112 1.55E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_04690 b3789da00de923b9f88aa186d53d9ae5 301 Gene3D G3DSA:1.10.10.10 3 86 4.2E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_04690 b3789da00de923b9f88aa186d53d9ae5 301 SUPERFAMILY SSF53850 91 297 2.53E-40 T 14-10-2018 LH59_04690 b3789da00de923b9f88aa186d53d9ae5 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 4.6E-15 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_07595 22c08cd50fa112ed5207262912f2344a 395 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 2 207 1.7E-58 T 14-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain LH59_07595 22c08cd50fa112ed5207262912f2344a 395 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 253 368 3.3E-30 T 14-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal LH59_07595 22c08cd50fa112ed5207262912f2344a 395 Gene3D G3DSA:3.40.50.300 1 226 5.0E-72 T 14-10-2018 LH59_07595 22c08cd50fa112ed5207262912f2344a 395 SUPERFAMILY SSF52540 2 305 2.74E-46 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_07595 22c08cd50fa112ed5207262912f2344a 395 SMART SM00833 253 368 6.3E-52 T 14-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal LH59_20720 e3ccc098b4bc720fcc3f9998b6ff551d 248 SUPERFAMILY SSF49354 25 145 1.75E-33 T 14-10-2018 IPR008962 PapD-like superfamily LH59_20720 e3ccc098b4bc720fcc3f9998b6ff551d 248 ProSitePatterns PS00635 Gram-negative pili assembly chaperone signature. 101 118 - T 14-10-2018 IPR018046 Pili assembly chaperone, conserved site LH59_20720 e3ccc098b4bc720fcc3f9998b6ff551d 248 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 25 145 3.0E-34 T 14-10-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 LH59_20720 e3ccc098b4bc720fcc3f9998b6ff551d 248 Gene3D G3DSA:2.60.40.10 25 143 1.0E-33 T 14-10-2018 IPR013783 Immunoglobulin-like fold LH59_20720 e3ccc098b4bc720fcc3f9998b6ff551d 248 Gene3D G3DSA:2.60.40.10 148 241 3.6E-18 T 14-10-2018 IPR013783 Immunoglobulin-like fold LH59_20720 e3ccc098b4bc720fcc3f9998b6ff551d 248 SUPERFAMILY SSF49584 155 241 5.89E-18 T 14-10-2018 IPR036316 Pili assembly chaperone, C-terminal domain superfamily LH59_20720 e3ccc098b4bc720fcc3f9998b6ff551d 248 Pfam PF02753 Pili assembly chaperone PapD, C-terminal domain 169 228 1.9E-11 T 14-10-2018 IPR016148 Pili assembly chaperone, C-terminal LH59_20720 e3ccc098b4bc720fcc3f9998b6ff551d 248 PRINTS PR00969 Pili chaperone signature 70 91 2.0E-29 T 14-10-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 LH59_20720 e3ccc098b4bc720fcc3f9998b6ff551d 248 PRINTS PR00969 Pili chaperone signature 127 142 2.0E-29 T 14-10-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 LH59_20720 e3ccc098b4bc720fcc3f9998b6ff551d 248 PRINTS PR00969 Pili chaperone signature 102 119 2.0E-29 T 14-10-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 LH59_20720 e3ccc098b4bc720fcc3f9998b6ff551d 248 PRINTS PR00969 Pili chaperone signature 163 178 2.0E-29 T 14-10-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 LH59_20720 e3ccc098b4bc720fcc3f9998b6ff551d 248 PRINTS PR00969 Pili chaperone signature 25 34 2.0E-29 T 14-10-2018 IPR001829 Pili assembly chaperone, bacterial GO:0030288|GO:0043711|GO:0061077 LH59_01485 a7acb5bf85bde31532b3533153cfba7a 234 Gene3D G3DSA:2.60.40.10 29 140 1.0E-5 T 14-10-2018 IPR013783 Immunoglobulin-like fold LH59_01485 a7acb5bf85bde31532b3533153cfba7a 234 Pfam PF00345 Pili and flagellar-assembly chaperone, PapD N-terminal domain 22 138 2.3E-16 T 14-10-2018 IPR016147 Pili assembly chaperone, N-terminal GO:0030288|GO:0071555 LH59_01485 a7acb5bf85bde31532b3533153cfba7a 234 SUPERFAMILY SSF49354 17 138 1.88E-20 T 14-10-2018 IPR008962 PapD-like superfamily LH59_00500 5620185196bb291f2fd1196f3488937e 354 SUPERFAMILY SSF56112 16 338 1.46E-60 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily LH59_00500 5620185196bb291f2fd1196f3488937e 354 Pfam PF01636 Phosphotransferase enzyme family 35 285 1.2E-50 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase LH59_00500 5620185196bb291f2fd1196f3488937e 354 Gene3D G3DSA:3.30.200.20 15 113 2.0E-33 T 14-10-2018 LH59_00500 5620185196bb291f2fd1196f3488937e 354 Gene3D G3DSA:3.90.1200.10 114 347 3.6E-95 T 14-10-2018 LH59_22575 ec1c05626ba834f62b983f180465e65f 563 SUPERFAMILY SSF52091 437 551 2.16E-14 T 14-10-2018 IPR036513 STAS domain superfamily LH59_22575 ec1c05626ba834f62b983f180465e65f 563 Gene3D G3DSA:3.30.750.24 433 555 3.7E-25 T 14-10-2018 IPR036513 STAS domain superfamily LH59_22575 ec1c05626ba834f62b983f180465e65f 563 Pfam PF01740 STAS domain 438 546 1.6E-12 T 14-10-2018 IPR002645 STAS domain LH59_22575 ec1c05626ba834f62b983f180465e65f 563 Pfam PF00916 Sulfate permease family 23 381 2.7E-79 T 14-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 LH59_24245 8c2f9a8d11937543a77443ecbf39ec4e 235 Pfam PF01323 DSBA-like thioredoxin domain 29 211 4.3E-20 T 14-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 LH59_24245 8c2f9a8d11937543a77443ecbf39ec4e 235 SUPERFAMILY SSF52833 26 210 6.16E-34 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_24245 8c2f9a8d11937543a77443ecbf39ec4e 235 Gene3D G3DSA:3.40.30.10 24 228 3.0E-39 T 14-10-2018 LH59_23220 920b65a108846dde36e5abedf9a7a883 230 Pfam PF13280 WYL domain 138 208 2.9E-12 T 14-10-2018 IPR026881 WYL domain LH59_23220 920b65a108846dde36e5abedf9a7a883 230 Gene3D G3DSA:1.10.10.10 1 64 1.9E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_23220 920b65a108846dde36e5abedf9a7a883 230 SUPERFAMILY SSF46785 1 62 2.72E-10 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_23220 920b65a108846dde36e5abedf9a7a883 230 Pfam PF08279 HTH domain 6 59 1.1E-16 T 14-10-2018 IPR013196 Helix-turn-helix, type 11 LH59_02645 1ee5a08abed29a949e0133db7fefa8ed 396 SUPERFAMILY SSF161098 88 156 2.29E-12 T 14-10-2018 IPR035906 MetI-like superfamily LH59_02645 1ee5a08abed29a949e0133db7fefa8ed 396 Gene3D G3DSA:1.10.3720.10 82 177 5.8E-9 T 14-10-2018 IPR035906 MetI-like superfamily LH59_02645 1ee5a08abed29a949e0133db7fefa8ed 396 SUPERFAMILY SSF161098 190 377 3.14E-26 T 14-10-2018 IPR035906 MetI-like superfamily LH59_02645 1ee5a08abed29a949e0133db7fefa8ed 396 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 88 152 2.4E-17 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 LH59_02645 1ee5a08abed29a949e0133db7fefa8ed 396 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 266 391 2.3E-15 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_02645 1ee5a08abed29a949e0133db7fefa8ed 396 Gene3D G3DSA:1.10.3720.10 182 392 1.5E-35 T 14-10-2018 IPR035906 MetI-like superfamily LH59_17150 f758be7891549648de3d2a1c2c7ff4bd 706 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 72 706 3.8E-109 T 14-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 LH59_17150 f758be7891549648de3d2a1c2c7ff4bd 706 Gene3D G3DSA:2.170.130.10 47 180 5.5E-38 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily LH59_17150 f758be7891549648de3d2a1c2c7ff4bd 706 Pfam PF07715 TonB-dependent Receptor Plug Domain 70 170 7.8E-22 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_17150 f758be7891549648de3d2a1c2c7ff4bd 706 Gene3D G3DSA:2.40.170.20 181 706 4.6E-131 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_17150 f758be7891549648de3d2a1c2c7ff4bd 706 Pfam PF00593 TonB dependent receptor 265 705 1.6E-53 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_17150 f758be7891549648de3d2a1c2c7ff4bd 706 SUPERFAMILY SSF56935 31 706 4.37E-134 T 14-10-2018 LH59_04005 04cf2ddb2897dda88fc6c797745b6e13 142 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 117 2.0E-59 T 14-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 LH59_04005 04cf2ddb2897dda88fc6c797745b6e13 142 Pfam PF02381 MraZ protein, putative antitoxin-like 73 120 1.5E-10 T 14-10-2018 IPR020603 MraZ domain LH59_04005 04cf2ddb2897dda88fc6c797745b6e13 142 Pfam PF02381 MraZ protein, putative antitoxin-like 2 69 2.6E-13 T 14-10-2018 IPR020603 MraZ domain LH59_04005 04cf2ddb2897dda88fc6c797745b6e13 142 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 142 48.166 T 14-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 LH59_04005 04cf2ddb2897dda88fc6c797745b6e13 142 Gene3D G3DSA:2.40.330.20 1 137 3.4E-36 T 14-10-2018 IPR038619 MraZ superfamily LH59_04005 04cf2ddb2897dda88fc6c797745b6e13 142 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 2 129 6.4E-35 T 14-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 LH59_04005 04cf2ddb2897dda88fc6c797745b6e13 142 SUPERFAMILY SSF89447 2 128 2.47E-37 T 14-10-2018 IPR037914 SpoVT-AbrB domain superfamily LH59_03030 d4608d80a7946ea466033d1d2e351874 54 PIRSF PIRSF000071 1 54 4.1E-26 T 14-10-2018 IPR024922 Rubredoxin GO:0005506|GO:0009055 LH59_03030 d4608d80a7946ea466033d1d2e351874 54 Pfam PF00301 Rubredoxin 4 49 6.5E-23 T 14-10-2018 IPR024935 Rubredoxin domain GO:0005506 LH59_03030 d4608d80a7946ea466033d1d2e351874 54 ProSitePatterns PS00202 Rubredoxin signature. 33 43 - T 14-10-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 LH59_03030 d4608d80a7946ea466033d1d2e351874 54 Gene3D G3DSA:2.20.28.10 1 54 2.9E-27 T 14-10-2018 LH59_03030 d4608d80a7946ea466033d1d2e351874 54 SUPERFAMILY SSF57802 1 53 3.2E-23 T 14-10-2018 LH59_03030 d4608d80a7946ea466033d1d2e351874 54 PRINTS PR00163 Rubredoxin signature 3 19 3.4E-8 T 14-10-2018 IPR024935 Rubredoxin domain GO:0005506 LH59_03030 d4608d80a7946ea466033d1d2e351874 54 PRINTS PR00163 Rubredoxin signature 33 49 3.4E-8 T 14-10-2018 IPR024935 Rubredoxin domain GO:0005506 LH59_27500 4dfc2c3a6ad1415a258873accccd4f2c 220 Pfam PF04367 Protein of unknown function (DUF502) 56 161 3.8E-37 T 14-10-2018 IPR007462 Protein of unknown function DUF502 LH59_05370 cdb0466bf12b9490a5040af8bf9c928c 141 Pfam PF08897 Domain of unknown function (DUF1841) 5 136 1.6E-57 T 14-10-2018 IPR014993 Protein of unknown function DUF1841 LH59_10075 61b33c191482a62f454149428d394739 312 Pfam PF12146 Serine aminopeptidase, S33 35 146 3.9E-14 T 14-10-2018 IPR022742 Serine aminopeptidase, S33 LH59_10075 61b33c191482a62f454149428d394739 312 Gene3D G3DSA:3.40.50.1820 1 286 1.9E-24 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_10075 61b33c191482a62f454149428d394739 312 PIRSF PIRSF037442 1 289 3.9E-101 T 14-10-2018 IPR017208 Uncharacterised conserved protein UCP037442, alpha/beta hydrolase, RSp0795 LH59_10075 61b33c191482a62f454149428d394739 312 SUPERFAMILY SSF53474 4 285 8.11E-27 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_07165 c150b0b30094c04a37fe641d053647f9 397 Gene3D G3DSA:1.10.530.10 68 316 3.8E-78 T 14-10-2018 LH59_07165 c150b0b30094c04a37fe641d053647f9 397 Pfam PF01471 Putative peptidoglycan binding domain 338 393 1.9E-13 T 14-10-2018 IPR002477 Peptidoglycan binding-like LH59_07165 c150b0b30094c04a37fe641d053647f9 397 SUPERFAMILY SSF53955 12 324 7.87E-97 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily LH59_07165 c150b0b30094c04a37fe641d053647f9 397 SUPERFAMILY SSF47090 324 394 7.85E-19 T 14-10-2018 IPR036365 PGBD-like superfamily LH59_07165 c150b0b30094c04a37fe641d053647f9 397 Pfam PF13406 Transglycosylase SLT domain 26 317 6.1E-100 T 14-10-2018 IPR031304 Transglycosylase SLT domain 2 LH59_07165 c150b0b30094c04a37fe641d053647f9 397 Gene3D G3DSA:1.10.101.10 324 397 6.5E-13 T 14-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 LH59_07165 c150b0b30094c04a37fe641d053647f9 397 TIGRFAM TIGR02283 MltB_2: lytic murein transglycosylase 26 320 1.3E-106 T 14-10-2018 IPR011970 Lytic murein transglycosylase LH59_07165 c150b0b30094c04a37fe641d053647f9 397 Gene3D G3DSA:1.10.8.350 38 201 3.8E-78 T 14-10-2018 LH59_06820 467f73261c6c18e0547e049342e015e0 173 Gene3D G3DSA:2.160.10.10 1 172 1.5E-56 T 14-10-2018 LH59_06820 467f73261c6c18e0547e049342e015e0 173 SUPERFAMILY SSF51161 1 169 3.6E-42 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily LH59_06820 467f73261c6c18e0547e049342e015e0 173 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 88 121 5.3E-9 T 14-10-2018 IPR001451 Hexapeptide repeat LH59_18115 770d6ea16bb57d0d0c9d7067091fafe6 276 Gene3D G3DSA:1.10.600.10 3 256 1.1E-83 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily LH59_18115 770d6ea16bb57d0d0c9d7067091fafe6 276 SUPERFAMILY SSF48576 5 275 1.21E-67 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily LH59_18115 770d6ea16bb57d0d0c9d7067091fafe6 276 TIGRFAM TIGR03464 HpnC: squalene synthase HpnC 2 275 7.4E-114 T 14-10-2018 IPR017827 Hydroxysqualene synthase HpnC MetaCyc: PWY-7072 LH59_18115 770d6ea16bb57d0d0c9d7067091fafe6 276 Pfam PF00494 Squalene/phytoene synthase 5 262 1.8E-64 T 14-10-2018 LH59_10260 09062cb70b44c24db8c36e94da1903db 209 Pfam PF13649 Methyltransferase domain 54 143 9.6E-16 T 14-10-2018 LH59_10260 09062cb70b44c24db8c36e94da1903db 209 Gene3D G3DSA:3.40.50.150 6 209 5.3E-41 T 14-10-2018 LH59_10260 09062cb70b44c24db8c36e94da1903db 209 SUPERFAMILY SSF53335 19 193 2.26E-36 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_01735 8d5eb6fd477844137bba611d8c2ddfad 311 SUPERFAMILY SSF144020 22 307 8.89E-83 T 14-10-2018 IPR024064 FdhE-like superfamily LH59_01735 8d5eb6fd477844137bba611d8c2ddfad 311 Pfam PF04216 Protein involved in formate dehydrogenase formation 17 305 1.2E-109 T 14-10-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 LH59_01735 8d5eb6fd477844137bba611d8c2ddfad 311 PIRSF PIRSF018296 1 310 8.2E-99 T 14-10-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 LH59_01735 8d5eb6fd477844137bba611d8c2ddfad 311 TIGRFAM TIGR01562 FdhE: formate dehydrogenase accessory protein FdhE 3 304 3.9E-87 T 14-10-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 LH59_01735 8d5eb6fd477844137bba611d8c2ddfad 311 Hamap MF_00611 Protein FdhE [fdhE]. 2 307 34.894 T 14-10-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 LH59_01735 8d5eb6fd477844137bba611d8c2ddfad 311 Gene3D G3DSA:3.90.1670.10 19 309 1.5E-98 T 14-10-2018 IPR024064 FdhE-like superfamily LH59_27715 d854cd6fe56999004706e3b32968c5d9 145 Pfam PF01230 HIT domain 13 103 5.3E-17 T 14-10-2018 IPR001310 Histidine triad (HIT) protein LH59_27715 d854cd6fe56999004706e3b32968c5d9 145 Gene3D G3DSA:3.30.428.10 1 144 9.8E-35 T 14-10-2018 IPR036265 HIT-like superfamily LH59_27715 d854cd6fe56999004706e3b32968c5d9 145 SUPERFAMILY SSF54197 3 139 1.14E-31 T 14-10-2018 IPR036265 HIT-like superfamily LH59_27715 d854cd6fe56999004706e3b32968c5d9 145 PRINTS PR00332 Histidine triad family signature 6 22 4.0E-14 T 14-10-2018 IPR001310 Histidine triad (HIT) protein LH59_27715 d854cd6fe56999004706e3b32968c5d9 145 PRINTS PR00332 Histidine triad family signature 27 45 4.0E-14 T 14-10-2018 IPR001310 Histidine triad (HIT) protein LH59_27715 d854cd6fe56999004706e3b32968c5d9 145 PRINTS PR00332 Histidine triad family signature 89 99 4.0E-14 T 14-10-2018 IPR001310 Histidine triad (HIT) protein LH59_10340 48cab55d566efe307927eaed46d8feb8 385 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 280 286 - T 14-10-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 Reactome: R-HSA-9033241 LH59_10340 48cab55d566efe307927eaed46d8feb8 385 SUPERFAMILY SSF51395 8 381 7.94E-86 T 14-10-2018 LH59_10340 48cab55d566efe307927eaed46d8feb8 385 Gene3D G3DSA:3.20.20.70 2 385 2.6E-115 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_10340 48cab55d566efe307927eaed46d8feb8 385 Pfam PF01070 FMN-dependent dehydrogenase 18 382 7.9E-117 T 14-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 LH59_10340 48cab55d566efe307927eaed46d8feb8 385 PIRSF PIRSF000138 1 385 7.0E-119 T 14-10-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 Reactome: R-HSA-9033241 LH59_21830 a6292d96266c89272a09a7b455584331 155 Pfam PF02627 Carboxymuconolactone decarboxylase family 13 94 2.8E-16 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 LH59_21830 a6292d96266c89272a09a7b455584331 155 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 29 77 1.3E-13 T 14-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 LH59_21830 a6292d96266c89272a09a7b455584331 155 SUPERFAMILY SSF69118 5 145 4.06E-42 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 LH59_21830 a6292d96266c89272a09a7b455584331 155 Gene3D G3DSA:1.20.1290.10 1 152 5.8E-49 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 LH59_24495 2444c7ecacb3e778fbcb05d203aebf91 148 SMART SM00347 24 124 2.8E-17 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_24495 2444c7ecacb3e778fbcb05d203aebf91 148 SUPERFAMILY SSF46785 9 139 1.07E-29 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_24495 2444c7ecacb3e778fbcb05d203aebf91 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 84 100 1.5E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_24495 2444c7ecacb3e778fbcb05d203aebf91 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 48 64 1.5E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_24495 2444c7ecacb3e778fbcb05d203aebf91 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 114 134 1.5E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_24495 2444c7ecacb3e778fbcb05d203aebf91 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 65 80 1.5E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_24495 2444c7ecacb3e778fbcb05d203aebf91 148 Pfam PF01047 MarR family 34 87 2.8E-12 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_24495 2444c7ecacb3e778fbcb05d203aebf91 148 Gene3D G3DSA:1.10.10.10 2 140 4.8E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_05730 a26f53897e3ff81dee764510692333cf 167 Pfam PF03840 Preprotein translocase SecG subunit 7 76 1.5E-21 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 LH59_05730 a26f53897e3ff81dee764510692333cf 167 PRINTS PR01651 Protein-export SecG membrane protein signature 26 40 1.3E-29 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 LH59_05730 a26f53897e3ff81dee764510692333cf 167 PRINTS PR01651 Protein-export SecG membrane protein signature 41 57 1.3E-29 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 LH59_05730 a26f53897e3ff81dee764510692333cf 167 PRINTS PR01651 Protein-export SecG membrane protein signature 57 79 1.3E-29 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 LH59_05730 a26f53897e3ff81dee764510692333cf 167 PRINTS PR01651 Protein-export SecG membrane protein signature 6 26 1.3E-29 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 LH59_05730 a26f53897e3ff81dee764510692333cf 167 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 7 76 9.6E-25 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 LH59_02130 10032336d19ef3979bd06c1466db8a7c 474 Gene3D G3DSA:3.40.630.10 52 438 4.5E-84 T 14-10-2018 LH59_02130 10032336d19ef3979bd06c1466db8a7c 474 Pfam PF01546 Peptidase family M20/M25/M40 92 453 2.6E-21 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 LH59_02130 10032336d19ef3979bd06c1466db8a7c 474 SUPERFAMILY SSF53187 21 458 5.09E-47 T 14-10-2018 LH59_02130 10032336d19ef3979bd06c1466db8a7c 474 Gene3D G3DSA:3.30.70.360 208 371 4.5E-84 T 14-10-2018 LH59_02130 10032336d19ef3979bd06c1466db8a7c 474 Pfam PF07687 Peptidase dimerisation domain 206 357 3.8E-8 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain LH59_05870 4fccd51941e4b4d97c0b4fb1e0f80ed7 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 218 6.0E-18 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_05870 4fccd51941e4b4d97c0b4fb1e0f80ed7 232 SMART SM00448 1 112 1.8E-37 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_05870 4fccd51941e4b4d97c0b4fb1e0f80ed7 232 Pfam PF00072 Response regulator receiver domain 3 111 5.7E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_05870 4fccd51941e4b4d97c0b4fb1e0f80ed7 232 Gene3D G3DSA:3.40.50.2300 1 121 3.6E-37 T 14-10-2018 LH59_05870 4fccd51941e4b4d97c0b4fb1e0f80ed7 232 SUPERFAMILY SSF52172 1 162 5.27E-39 T 14-10-2018 IPR011006 CheY-like superfamily LH59_05870 4fccd51941e4b4d97c0b4fb1e0f80ed7 232 Gene3D G3DSA:1.10.10.10 123 229 1.6E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_05870 4fccd51941e4b4d97c0b4fb1e0f80ed7 232 SMART SM00862 145 218 1.5E-18 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_08650 74a347fd4be0c6578e22ae1ec3ba2ef6 118 Pfam PF03960 ArsC family 41 114 1.2E-11 T 14-10-2018 IPR006660 Arsenate reductase-like LH59_08650 74a347fd4be0c6578e22ae1ec3ba2ef6 118 Gene3D G3DSA:3.40.30.10 3 118 6.2E-35 T 14-10-2018 LH59_08650 74a347fd4be0c6578e22ae1ec3ba2ef6 118 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 5 114 5.2E-27 T 14-10-2018 IPR006504 Transcriptional regulator Spx/MgsR LH59_08650 74a347fd4be0c6578e22ae1ec3ba2ef6 118 SUPERFAMILY SSF52833 4 116 3.31E-30 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_03765 a180cbca7940116a7b4cc878c9803d76 156 Gene3D G3DSA:1.10.10.10 8 59 5.7E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_03765 a180cbca7940116a7b4cc878c9803d76 156 SUPERFAMILY SSF54909 68 153 5.36E-21 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel LH59_03765 a180cbca7940116a7b4cc878c9803d76 156 Pfam PF01037 Lrp/AsnC ligand binding domain 73 147 8.0E-24 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LH59_03765 a180cbca7940116a7b4cc878c9803d76 156 Gene3D G3DSA:3.30.70.920 60 144 3.2E-24 T 14-10-2018 LH59_03765 a180cbca7940116a7b4cc878c9803d76 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 34 1.0E-17 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_03765 a180cbca7940116a7b4cc878c9803d76 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 53 1.0E-17 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_03765 a180cbca7940116a7b4cc878c9803d76 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 7 23 1.0E-17 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_03765 a180cbca7940116a7b4cc878c9803d76 156 SMART SM00344 7 116 1.9E-48 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 LH59_03765 a180cbca7940116a7b4cc878c9803d76 156 Pfam PF13412 Winged helix-turn-helix DNA-binding 8 54 1.3E-19 T 14-10-2018 LH59_03765 a180cbca7940116a7b4cc878c9803d76 156 SUPERFAMILY SSF46785 7 66 5.62E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_15970 6165396376565ca29e14f3b74696915c 147 Gene3D G3DSA:1.10.10.10 1 144 2.3E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_15970 6165396376565ca29e14f3b74696915c 147 Pfam PF02082 Transcriptional regulator 1 81 9.4E-17 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type LH59_15970 6165396376565ca29e14f3b74696915c 147 SUPERFAMILY SSF46785 8 131 5.88E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_26215 44c80f38ef956d4234db84db8c1b87ea 325 Gene3D G3DSA:3.90.25.10 177 314 1.4E-122 T 14-10-2018 LH59_26215 44c80f38ef956d4234db84db8c1b87ea 325 Gene3D G3DSA:3.40.50.720 8 304 1.4E-122 T 14-10-2018 LH59_26215 44c80f38ef956d4234db84db8c1b87ea 325 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 205 1.7E-24 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 LH59_26215 44c80f38ef956d4234db84db8c1b87ea 325 SUPERFAMILY SSF51735 1 318 1.19E-51 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_05900 3819ec1a4aee6d2a2c054a42e543d7c4 277 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 4 265 1.9E-107 T 14-10-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 LH59_05900 3819ec1a4aee6d2a2c054a42e543d7c4 277 Pfam PF00483 Nucleotidyl transferase 11 268 1.0E-23 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 LH59_05900 3819ec1a4aee6d2a2c054a42e543d7c4 277 SUPERFAMILY SSF53448 3 269 1.46E-65 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases LH59_05900 3819ec1a4aee6d2a2c054a42e543d7c4 277 Gene3D G3DSA:3.90.550.10 1 276 1.0E-83 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases LH59_17875 3b765544c51e1fbff073ba6f8ecf48b9 438 Pfam PF04403 Paraquat-inducible protein A 48 199 1.2E-39 T 14-10-2018 IPR007498 Intermembrane transport protein PqiA-like LH59_17875 3b765544c51e1fbff073ba6f8ecf48b9 438 Pfam PF04403 Paraquat-inducible protein A 258 412 1.5E-50 T 14-10-2018 IPR007498 Intermembrane transport protein PqiA-like LH59_17875 3b765544c51e1fbff073ba6f8ecf48b9 438 TIGRFAM TIGR00155 pqiA_fam: integral membrane protein, PqiA family 9 412 2.1E-80 T 14-10-2018 IPR005219 Intermembrane transport protein PqiA-like, Enterobacteria-type LH59_22660 3227b207dc5f303ebae65c73d0ae7f68 136 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 10 118 2.8E-19 T 14-10-2018 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III LH59_16630 5d3d41cf113a5771599ba2b18c7fd5b8 432 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 427 9.6E-104 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 LH59_16630 5d3d41cf113a5771599ba2b18c7fd5b8 432 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 7 422 2.4E-95 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit LH59_16630 5d3d41cf113a5771599ba2b18c7fd5b8 432 PIRSF PIRSF006066 1 432 1.0E-118 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 LH59_12240 e3c07dd39113798e71b835bd5b9ff1f4 971 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 103 123 5.2E-40 T 14-10-2018 LH59_12240 e3c07dd39113798e71b835bd5b9ff1f4 971 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 75 100 5.2E-40 T 14-10-2018 LH59_12240 e3c07dd39113798e71b835bd5b9ff1f4 971 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 216 237 5.2E-40 T 14-10-2018 LH59_12240 e3c07dd39113798e71b835bd5b9ff1f4 971 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 415 434 5.2E-40 T 14-10-2018 LH59_12240 e3c07dd39113798e71b835bd5b9ff1f4 971 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 306 318 5.2E-40 T 14-10-2018 LH59_12240 e3c07dd39113798e71b835bd5b9ff1f4 971 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 238 264 5.2E-40 T 14-10-2018 LH59_12240 e3c07dd39113798e71b835bd5b9ff1f4 971 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 150 171 5.2E-40 T 14-10-2018 LH59_12240 e3c07dd39113798e71b835bd5b9ff1f4 971 Pfam PF00361 Proton-conducting membrane transporter 126 406 9.9E-66 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_12240 e3c07dd39113798e71b835bd5b9ff1f4 971 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 66 113 2.6E-9 T 14-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_12240 e3c07dd39113798e71b835bd5b9ff1f4 971 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 819 940 1.2E-31 T 14-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein LH59_12240 e3c07dd39113798e71b835bd5b9ff1f4 971 Pfam PF13244 Domain of unknown function (DUF4040) 614 678 2.7E-18 T 14-10-2018 IPR025383 Domain of unknown function DUF4040 LH59_05100 12a8070fd3696ac1f6725bcde98e70e6 140 Pfam PF13474 SnoaL-like domain 10 124 8.9E-16 T 14-10-2018 IPR037401 SnoaL-like domain LH59_05100 12a8070fd3696ac1f6725bcde98e70e6 140 SUPERFAMILY SSF54427 2 123 3.15E-32 T 14-10-2018 IPR032710 NTF2-like domain superfamily LH59_05100 12a8070fd3696ac1f6725bcde98e70e6 140 Gene3D G3DSA:3.10.450.50 1 131 5.1E-36 T 14-10-2018 LH59_19760 c02df37fe675c43ebda891ffc59f8c39 152 PIRSF PIRSF032131 3 150 2.4E-46 T 14-10-2018 IPR009562 Protein of unknown function DUF1178 LH59_19760 c02df37fe675c43ebda891ffc59f8c39 152 Pfam PF06676 Protein of unknown function (DUF1178) 4 144 7.9E-51 T 14-10-2018 IPR009562 Protein of unknown function DUF1178 LH59_26005 8764e1c8f9eda35962ba59518f86ea8a 334 Pfam PF02653 Branched-chain amino acid transport system / permease component 29 291 6.0E-44 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_20400 57b4d06417c1c973e76936a57b80712a 261 Pfam PF00459 Inositol monophosphatase family 2 249 2.6E-60 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 LH59_20400 57b4d06417c1c973e76936a57b80712a 261 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 209 223 - T 14-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 LH59_20400 57b4d06417c1c973e76936a57b80712a 261 PRINTS PR01959 SuhB family inositol monophosphatase signature 104 123 7.8E-17 T 14-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 LH59_20400 57b4d06417c1c973e76936a57b80712a 261 PRINTS PR01959 SuhB family inositol monophosphatase signature 196 208 7.8E-17 T 14-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 LH59_20400 57b4d06417c1c973e76936a57b80712a 261 PRINTS PR01959 SuhB family inositol monophosphatase signature 17 39 7.8E-17 T 14-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 LH59_20400 57b4d06417c1c973e76936a57b80712a 261 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 81 94 - T 14-10-2018 IPR020583 Inositol monophosphatase, metal-binding site LH59_20400 57b4d06417c1c973e76936a57b80712a 261 Gene3D G3DSA:3.40.190.80 141 259 4.5E-31 T 14-10-2018 LH59_20400 57b4d06417c1c973e76936a57b80712a 261 Gene3D G3DSA:3.30.540.10 1 140 6.2E-51 T 14-10-2018 LH59_20400 57b4d06417c1c973e76936a57b80712a 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 130 153 7.7E-56 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 LH59_20400 57b4d06417c1c973e76936a57b80712a 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 60 76 7.7E-56 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 LH59_20400 57b4d06417c1c973e76936a57b80712a 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 81 97 7.7E-56 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 LH59_20400 57b4d06417c1c973e76936a57b80712a 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 175 196 7.7E-56 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 LH59_20400 57b4d06417c1c973e76936a57b80712a 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 206 230 7.7E-56 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 LH59_20400 57b4d06417c1c973e76936a57b80712a 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 38 58 7.7E-56 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 LH59_20400 57b4d06417c1c973e76936a57b80712a 261 SUPERFAMILY SSF56655 1 258 8.64E-82 T 14-10-2018 LH59_00075 e333035f1a57d8ed0d01a865b18783e8 244 SUPERFAMILY SSF52540 1 226 3.44E-74 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_00075 e333035f1a57d8ed0d01a865b18783e8 244 Gene3D G3DSA:3.40.50.300 1 242 2.6E-73 T 14-10-2018 LH59_00075 e333035f1a57d8ed0d01a865b18783e8 244 PIRSF PIRSF039085 1 243 2.2E-98 T 14-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 LH59_00075 e333035f1a57d8ed0d01a865b18783e8 244 Pfam PF00005 ABC transporter 17 165 1.5E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_00075 e333035f1a57d8ed0d01a865b18783e8 244 SMART SM00382 26 213 1.9E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_00075 e333035f1a57d8ed0d01a865b18783e8 244 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_08915 02c12e6c83df9fa0b5f48587f5e4f3e0 296 SUPERFAMILY SSF103481 182 282 7.06E-17 T 14-10-2018 LH59_08915 02c12e6c83df9fa0b5f48587f5e4f3e0 296 Pfam PF00892 EamA-like transporter family 7 136 4.1E-9 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_08915 02c12e6c83df9fa0b5f48587f5e4f3e0 296 Pfam PF00892 EamA-like transporter family 148 277 4.0E-21 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_08915 02c12e6c83df9fa0b5f48587f5e4f3e0 296 SUPERFAMILY SSF103481 38 137 6.8E-9 T 14-10-2018 LH59_00360 497df454f290c0da6b3e73401acf3bf4 319 Gene3D G3DSA:3.40.190.10 31 316 5.7E-104 T 14-10-2018 LH59_00360 497df454f290c0da6b3e73401acf3bf4 319 SUPERFAMILY SSF53850 26 318 3.87E-74 T 14-10-2018 LH59_00360 497df454f290c0da6b3e73401acf3bf4 319 Gene3D G3DSA:3.40.190.10 115 251 5.7E-104 T 14-10-2018 LH59_00360 497df454f290c0da6b3e73401acf3bf4 319 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 7 316 5.0E-102 T 14-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family LH59_00360 497df454f290c0da6b3e73401acf3bf4 319 Pfam PF16868 NMT1-like family 31 316 2.5E-88 T 14-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family LH59_22720 962e76ff3f4b2703995c87f7de06efaa 276 Pfam PF09339 IclR helix-turn-helix domain 11 62 6.1E-15 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_22720 962e76ff3f4b2703995c87f7de06efaa 276 SUPERFAMILY SSF55781 67 273 1.37E-29 T 14-10-2018 LH59_22720 962e76ff3f4b2703995c87f7de06efaa 276 SUPERFAMILY SSF46785 9 82 8.84E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_22720 962e76ff3f4b2703995c87f7de06efaa 276 SMART SM00346 9 99 3.7E-21 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_22720 962e76ff3f4b2703995c87f7de06efaa 276 Gene3D G3DSA:1.10.10.10 3 77 7.7E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_22720 962e76ff3f4b2703995c87f7de06efaa 276 Gene3D G3DSA:3.30.450.40 83 268 1.2E-26 T 14-10-2018 IPR029016 GAF-like domain superfamily LH59_22720 962e76ff3f4b2703995c87f7de06efaa 276 Pfam PF01614 Bacterial transcriptional regulator 195 239 1.0E-5 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal LH59_04650 f8af1b05001fc6bbb2742b3d15e9b153 566 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 184 282 9.2E-18 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 LH59_04650 f8af1b05001fc6bbb2742b3d15e9b153 566 SUPERFAMILY SSF47203 291 450 6.77E-40 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 LH59_04650 f8af1b05001fc6bbb2742b3d15e9b153 566 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 293 448 9.1E-33 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LH59_04650 f8af1b05001fc6bbb2742b3d15e9b153 566 Gene3D G3DSA:1.20.140.10 294 450 1.5E-38 T 14-10-2018 LH59_04650 f8af1b05001fc6bbb2742b3d15e9b153 566 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 407 426 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 LH59_04650 f8af1b05001fc6bbb2742b3d15e9b153 566 SUPERFAMILY SSF56645 95 302 3.4E-43 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 LH59_04650 f8af1b05001fc6bbb2742b3d15e9b153 566 Gene3D G3DSA:2.40.110.20 141 293 4.6E-47 T 14-10-2018 LH59_09690 53f346e98498b595dd893b59c8a6a116 108 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 53 72 - T 14-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 LH59_09690 53f346e98498b595dd893b59c8a6a116 108 SMART SM00411 8 97 7.0E-44 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 LH59_09690 53f346e98498b595dd893b59c8a6a116 108 Hamap MF_00380 Integration host factor subunit alpha [ihfA]. 6 102 30.041 T 14-10-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 LH59_09690 53f346e98498b595dd893b59c8a6a116 108 Pfam PF00216 Bacterial DNA-binding protein 8 96 2.0E-31 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 LH59_09690 53f346e98498b595dd893b59c8a6a116 108 PRINTS PR01727 Prokaryotic integration host factor signature 47 62 5.0E-14 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 LH59_09690 53f346e98498b595dd893b59c8a6a116 108 PRINTS PR01727 Prokaryotic integration host factor signature 65 78 5.0E-14 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 LH59_09690 53f346e98498b595dd893b59c8a6a116 108 PRINTS PR01727 Prokaryotic integration host factor signature 81 95 5.0E-14 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 LH59_09690 53f346e98498b595dd893b59c8a6a116 108 SUPERFAMILY SSF47729 8 97 1.12E-32 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 LH59_09690 53f346e98498b595dd893b59c8a6a116 108 TIGRFAM TIGR00987 himA: integration host factor, alpha subunit 7 100 1.5E-43 T 14-10-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 LH59_09690 53f346e98498b595dd893b59c8a6a116 108 Gene3D G3DSA:4.10.520.10 6 103 8.2E-37 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 LH59_02540 5fd4e13c9ae45a0fe0853c2f83f15bbb 678 SUPERFAMILY SSF56935 22 678 2.07E-113 T 14-10-2018 LH59_02540 5fd4e13c9ae45a0fe0853c2f83f15bbb 678 Gene3D G3DSA:2.40.170.20 170 678 1.8E-72 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_02540 5fd4e13c9ae45a0fe0853c2f83f15bbb 678 Gene3D G3DSA:2.170.130.10 26 167 5.6E-30 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily LH59_02540 5fd4e13c9ae45a0fe0853c2f83f15bbb 678 Pfam PF00593 TonB dependent receptor 244 677 8.9E-50 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_02540 5fd4e13c9ae45a0fe0853c2f83f15bbb 678 Pfam PF07715 TonB-dependent Receptor Plug Domain 48 156 3.8E-21 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_02540 5fd4e13c9ae45a0fe0853c2f83f15bbb 678 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 41 - T 14-10-2018 IPR010916 TonB box, conserved site LH59_02505 bb564ef02e3e1da36effd040e8ac0354 292 Gene3D G3DSA:1.10.620.20 6 228 1.8E-13 T 14-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 LH59_02505 bb564ef02e3e1da36effd040e8ac0354 292 SUPERFAMILY SSF47240 12 278 1.71E-44 T 14-10-2018 IPR009078 Ferritin-like superfamily LH59_08040 4b04d1521db90babd8dd73dfc679dc52 176 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 14 174 36.437 T 14-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 LH59_08040 4b04d1521db90babd8dd73dfc679dc52 176 Pfam PF00719 Inorganic pyrophosphatase 18 174 2.8E-54 T 14-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 LH59_08040 4b04d1521db90babd8dd73dfc679dc52 176 Gene3D G3DSA:3.90.80.10 1 175 4.3E-70 T 14-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 LH59_08040 4b04d1521db90babd8dd73dfc679dc52 176 SUPERFAMILY SSF50324 3 175 9.55E-68 T 14-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 LH59_03855 e9fa4c0a070492d29e8b692120042666 309 Gene3D G3DSA:3.40.50.720 15 309 3.1E-105 T 14-10-2018 LH59_03855 e9fa4c0a070492d29e8b692120042666 309 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 103 274 1.7E-46 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 LH59_03855 e9fa4c0a070492d29e8b692120042666 309 Gene3D G3DSA:3.40.50.720 93 275 3.1E-105 T 14-10-2018 LH59_03855 e9fa4c0a070492d29e8b692120042666 309 SUPERFAMILY SSF51735 95 275 2.33E-47 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_12005 851f1f8e745e95c9135e8a56bde8e39c 264 Gene3D G3DSA:3.60.60.10 4 246 1.0E-5 T 14-10-2018 LH59_12005 851f1f8e745e95c9135e8a56bde8e39c 264 Pfam PF05742 Transport and Golgi organisation 2 1 238 6.1E-55 T 14-10-2018 IPR008551 Transport and Golgi organisation protein 2 LH59_26925 f6fb3422864c47a05ac71253ad4db9dc 149 SUPERFAMILY SSF55729 5 134 4.15E-31 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_26925 f6fb3422864c47a05ac71253ad4db9dc 149 Pfam PF00583 Acetyltransferase (GNAT) family 41 134 2.1E-13 T 14-10-2018 IPR000182 GNAT domain LH59_26925 f6fb3422864c47a05ac71253ad4db9dc 149 Gene3D G3DSA:3.40.630.30 2 147 5.6E-40 T 14-10-2018 LH59_19800 6da25e2e961f34566fedbb50cff9969a 451 Gene3D G3DSA:3.30.450.380 18 187 1.4E-36 T 14-10-2018 LH59_19800 6da25e2e961f34566fedbb50cff9969a 451 Gene3D G3DSA:3.40.50.300 188 415 9.0E-70 T 14-10-2018 LH59_19800 6da25e2e961f34566fedbb50cff9969a 451 Pfam PF00437 Type II/IV secretion system protein 92 368 2.0E-78 T 14-10-2018 IPR001482 Type II/IV secretion system protein LH59_19800 6da25e2e961f34566fedbb50cff9969a 451 SUPERFAMILY SSF52540 72 405 8.56E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_14150 cc612082bebc26f53e2309aa299a3f60 357 Pfam PF03060 Nitronate monooxygenase 9 338 7.7E-74 T 14-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 LH59_14150 cc612082bebc26f53e2309aa299a3f60 357 SUPERFAMILY SSF51412 8 329 8.97E-58 T 14-10-2018 LH59_14150 cc612082bebc26f53e2309aa299a3f60 357 Gene3D G3DSA:3.20.20.70 5 347 1.2E-99 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_25630 7198b05218bb66f6f65e704e148faa9c 155 Gene3D G3DSA:2.30.110.60 2 149 2.3E-15 T 14-10-2018 LH59_16350 de2e0c4c628cef4e82edc602e742bb16 147 Pfam PF05117 Family of unknown function (DUF695) 10 133 2.4E-24 T 14-10-2018 IPR016097 Domain of unknown function DUF695 LH59_12355 d9528a97336d779581eb315f9e31e0b5 252 Gene3D G3DSA:3.40.1210.10 1 250 1.4E-92 T 14-10-2018 IPR036523 SurE-like phosphatase/nucleotidase superfamily GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 LH59_12355 d9528a97336d779581eb315f9e31e0b5 252 SUPERFAMILY SSF64167 1 249 1.05E-84 T 14-10-2018 LH59_12355 d9528a97336d779581eb315f9e31e0b5 252 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 1 233 3.8E-64 T 14-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 LH59_12355 d9528a97336d779581eb315f9e31e0b5 252 Pfam PF01975 Survival protein SurE 3 182 3.8E-59 T 14-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 LH59_12355 d9528a97336d779581eb315f9e31e0b5 252 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 1 250 38.728 T 14-10-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 LH59_23720 f743d7f8068f0649b63e060912957139 213 SUPERFAMILY SSF81452 18 210 4.58E-59 T 14-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_23720 f743d7f8068f0649b63e060912957139 213 Gene3D G3DSA:1.20.120.80 27 212 1.3E-56 T 14-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_23720 f743d7f8068f0649b63e060912957139 213 TIGRFAM TIGR02842 CyoC: cytochrome o ubiquinol oxidase, subunit III 33 212 8.4E-84 T 14-10-2018 IPR014206 Cytochrome o ubiquinol oxidase, subunit III GO:0005886|GO:0008827|GO:0019646 LH59_23720 f743d7f8068f0649b63e060912957139 213 Pfam PF00510 Cytochrome c oxidase subunit III 27 210 8.7E-15 T 14-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_11485 9894fb20470f491fc1a1647451d8625a 107 TIGRFAM TIGR03500 FliO_TIGR: flagellar biosynthetic protein FliO 13 80 5.1E-23 T 14-10-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 LH59_11485 9894fb20470f491fc1a1647451d8625a 107 Pfam PF04347 Flagellar biosynthesis protein, FliO 25 105 1.0E-20 T 14-10-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 LH59_08435 0aa2b6ddbc4a05b74675508824c620fe 110 Pfam PF05957 Bacterial protein of unknown function (DUF883) 16 109 1.2E-22 T 14-10-2018 IPR010279 Inner membrane protein YqjD/ElaB GO:0043022 LH59_06500 617f4c5c163fcb52261ecf2e6003d481 311 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 6 311 4.3E-28 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain LH59_06500 617f4c5c163fcb52261ecf2e6003d481 311 Gene3D G3DSA:3.30.70.250 123 195 1.8E-94 T 14-10-2018 LH59_06500 617f4c5c163fcb52261ecf2e6003d481 311 SUPERFAMILY SSF55048 126 195 1.02E-17 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding LH59_06500 617f4c5c163fcb52261ecf2e6003d481 311 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 1 289 8.3E-104 T 14-10-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 LH59_06500 617f4c5c163fcb52261ecf2e6003d481 311 Gene3D G3DSA:3.40.366.10 4 282 1.8E-94 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 LH59_06500 617f4c5c163fcb52261ecf2e6003d481 311 SUPERFAMILY SSF52151 2 296 3.66E-68 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase LH59_06500 617f4c5c163fcb52261ecf2e6003d481 311 PIRSF PIRSF000446 1 309 4.9E-107 T 14-10-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 LH59_06500 617f4c5c163fcb52261ecf2e6003d481 311 Pfam PF00698 Acyl transferase domain 5 279 2.3E-35 T 14-10-2018 IPR014043 Acyl transferase LH59_25985 89cd3ceda4c77f6d987742a8c906f1d9 225 Gene3D G3DSA:1.10.10.10 1 67 1.2E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_25985 89cd3ceda4c77f6d987742a8c906f1d9 225 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 7.7E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_25985 89cd3ceda4c77f6d987742a8c906f1d9 225 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 7.7E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_25985 89cd3ceda4c77f6d987742a8c906f1d9 225 SUPERFAMILY SSF46785 3 70 1.95E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_25985 89cd3ceda4c77f6d987742a8c906f1d9 225 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 66 1.9E-15 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_25985 89cd3ceda4c77f6d987742a8c906f1d9 225 Pfam PF07729 FCD domain 78 205 2.6E-19 T 14-10-2018 IPR011711 GntR, C-terminal LH59_25985 89cd3ceda4c77f6d987742a8c906f1d9 225 SMART SM00345 8 66 2.7E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 LH59_25985 89cd3ceda4c77f6d987742a8c906f1d9 225 SMART SM00895 76 207 1.4E-20 T 14-10-2018 IPR011711 GntR, C-terminal LH59_25985 89cd3ceda4c77f6d987742a8c906f1d9 225 Gene3D G3DSA:1.20.120.530 77 212 9.6E-25 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_25985 89cd3ceda4c77f6d987742a8c906f1d9 225 SUPERFAMILY SSF48008 73 208 1.18E-21 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal LH59_15445 2d7a494c3fc47de10717ea5a0243c75d 161 SUPERFAMILY SSF160719 30 143 3.53E-11 T 14-10-2018 LH59_15445 2d7a494c3fc47de10717ea5a0243c75d 161 TIGRFAM TIGR03357 VI_zyme: type VI secretion system lysozyme-like protein 5 150 5.3E-37 T 14-10-2018 IPR017737 Type VI secretion system, lysozyme-related protein LH59_15445 2d7a494c3fc47de10717ea5a0243c75d 161 Pfam PF04965 Gene 25-like lysozyme 30 130 2.3E-21 T 14-10-2018 IPR007048 GpW/Gp25/anti-adapter protein IraD LH59_23905 9908c822f952ba57897b1324d763aae1 104 Gene3D G3DSA:1.10.10.10 3 104 1.2E-31 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_23905 9908c822f952ba57897b1324d763aae1 104 SMART SM00418 5 83 7.8E-24 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LH59_23905 9908c822f952ba57897b1324d763aae1 104 SUPERFAMILY SSF46785 5 96 1.61E-27 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_23905 9908c822f952ba57897b1324d763aae1 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 39 54 4.1E-13 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LH59_23905 9908c822f952ba57897b1324d763aae1 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 54 69 4.1E-13 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LH59_23905 9908c822f952ba57897b1324d763aae1 104 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 7 22 4.1E-13 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LH59_23905 9908c822f952ba57897b1324d763aae1 104 Pfam PF12840 Helix-turn-helix domain 5 63 1.4E-17 T 14-10-2018 LH59_01490 2ac50f5331339d45dcb624b4e6ae91ac 776 Gene3D G3DSA:2.60.40.2070 692 762 1.0E-5 T 14-10-2018 LH59_01490 2ac50f5331339d45dcb624b4e6ae91ac 776 Pfam PF00577 Outer membrane usher protein 474 683 8.2E-21 T 14-10-2018 IPR000015 Outer membrane usher protein GO:0009297|GO:0015473|GO:0016020 LH59_01490 2ac50f5331339d45dcb624b4e6ae91ac 776 Pfam PF00577 Outer membrane usher protein 252 392 6.4E-7 T 14-10-2018 IPR000015 Outer membrane usher protein GO:0009297|GO:0015473|GO:0016020 LH59_01490 2ac50f5331339d45dcb624b4e6ae91ac 776 Gene3D G3DSA:2.60.40.2610 597 687 1.3E-17 T 14-10-2018 LH59_01490 2ac50f5331339d45dcb624b4e6ae91ac 776 Pfam PF13953 PapC C-terminal domain 695 751 1.5E-9 T 14-10-2018 IPR025949 PapC-like, C-terminal domain LH59_21760 f616a779d1d8347e5b0f7bd49e4499c1 181 Pfam PF08281 Sigma-70, region 4 124 176 3.6E-10 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LH59_21760 f616a779d1d8347e5b0f7bd49e4499c1 181 Gene3D G3DSA:1.10.1740.10 6 89 2.7E-28 T 14-10-2018 LH59_21760 f616a779d1d8347e5b0f7bd49e4499c1 181 SUPERFAMILY SSF88946 2 109 1.81E-26 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 LH59_21760 f616a779d1d8347e5b0f7bd49e4499c1 181 SUPERFAMILY SSF88659 123 181 1.53E-12 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like LH59_21760 f616a779d1d8347e5b0f7bd49e4499c1 181 Gene3D G3DSA:1.10.10.10 98 181 7.9E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_21760 f616a779d1d8347e5b0f7bd49e4499c1 181 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 180 1.2E-24 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 LH59_21760 f616a779d1d8347e5b0f7bd49e4499c1 181 Pfam PF04542 Sigma-70 region 2 25 90 1.9E-18 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 LH59_06375 525d032e79a6d057b0a155d594549031 266 SUPERFAMILY SSF63380 7 108 7.53E-21 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel LH59_06375 525d032e79a6d057b0a155d594549031 266 SUPERFAMILY SSF52343 113 266 2.88E-30 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain LH59_06375 525d032e79a6d057b0a155d594549031 266 Gene3D G3DSA:3.40.50.80 106 266 3.3E-35 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain LH59_06375 525d032e79a6d057b0a155d594549031 266 PRINTS PR00410 Phenol hydroxylase reductase family signature 120 139 6.2E-8 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 LH59_06375 525d032e79a6d057b0a155d594549031 266 PRINTS PR00410 Phenol hydroxylase reductase family signature 145 154 6.2E-8 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 LH59_06375 525d032e79a6d057b0a155d594549031 266 PRINTS PR00410 Phenol hydroxylase reductase family signature 36 48 6.2E-8 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 LH59_06375 525d032e79a6d057b0a155d594549031 266 Pfam PF00175 Oxidoreductase NAD-binding domain 121 241 4.1E-9 T 14-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 LH59_06375 525d032e79a6d057b0a155d594549031 266 Gene3D G3DSA:2.40.30.10 1 104 4.2E-26 T 14-10-2018 LH59_08295 b6ae0aff46459bb08df416de4f9768ad 491 Pfam PF11863 Protein of unknown function (DUF3383) 7 489 2.2E-195 T 14-10-2018 IPR021808 Protein of unknown function DUF3383 LH59_01300 c9cfdac599194fd21ceee9024a43e9d3 225 Gene3D G3DSA:3.40.50.10070 42 170 7.8E-6 T 14-10-2018 IPR036752 TolB, N-terminal domain superfamily GO:0015031|GO:0042597 LH59_01300 c9cfdac599194fd21ceee9024a43e9d3 225 SUPERFAMILY SSF52964 47 145 1.7E-10 T 14-10-2018 LH59_01300 c9cfdac599194fd21ceee9024a43e9d3 225 Pfam PF03783 Curli production assembly/transport component CsgG 41 221 5.1E-36 T 14-10-2018 IPR005534 Curli production assembly/transport component CsgG GO:0030288 LH59_21260 6087f4f1a2aebf8b45b79d153f6c8a9e 116 Gene3D G3DSA:3.60.90.10 2 116 3.5E-39 T 14-10-2018 LH59_21260 6087f4f1a2aebf8b45b79d153f6c8a9e 116 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 7 116 2.5E-34 T 14-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 LH59_21260 6087f4f1a2aebf8b45b79d153f6c8a9e 116 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 4 116 24.129 T 14-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 LH59_21260 6087f4f1a2aebf8b45b79d153f6c8a9e 116 SUPERFAMILY SSF56276 7 116 7.45E-32 T 14-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 LH59_21260 6087f4f1a2aebf8b45b79d153f6c8a9e 116 Pfam PF02675 S-adenosylmethionine decarboxylase 10 116 7.2E-35 T 14-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 LH59_10060 cf70b1ad41dcdee64b22744a64f3c363 304 Pfam PF00892 EamA-like transporter family 151 283 2.1E-21 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_10060 cf70b1ad41dcdee64b22744a64f3c363 304 Pfam PF00892 EamA-like transporter family 3 135 2.6E-22 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_10060 cf70b1ad41dcdee64b22744a64f3c363 304 SUPERFAMILY SSF103481 41 138 1.05E-13 T 14-10-2018 LH59_10060 cf70b1ad41dcdee64b22744a64f3c363 304 SUPERFAMILY SSF103481 186 285 1.7E-12 T 14-10-2018 LH59_20095 05050ac736879489069199e2d83f31db 324 SUPERFAMILY SSF53850 33 260 7.06E-5 T 14-10-2018 LH59_20095 05050ac736879489069199e2d83f31db 324 Gene3D G3DSA:3.40.190.10 126 248 2.4E-72 T 14-10-2018 LH59_20095 05050ac736879489069199e2d83f31db 324 Gene3D G3DSA:3.40.190.150 32 313 2.4E-72 T 14-10-2018 LH59_20095 05050ac736879489069199e2d83f31db 324 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 319 2.3E-42 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_20095 05050ac736879489069199e2d83f31db 324 PIRSF PIRSF017082 2 323 3.8E-55 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_19525 56c880ff4f3a7a38a15ea27164c79977 338 Pfam PF00561 alpha/beta hydrolase fold 69 198 1.3E-15 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_19525 56c880ff4f3a7a38a15ea27164c79977 338 SUPERFAMILY SSF53474 46 334 2.56E-53 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_19525 56c880ff4f3a7a38a15ea27164c79977 338 PRINTS PR00412 Epoxide hydrolase signature 92 107 1.7E-13 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 LH59_19525 56c880ff4f3a7a38a15ea27164c79977 338 PRINTS PR00412 Epoxide hydrolase signature 313 335 1.7E-13 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 LH59_19525 56c880ff4f3a7a38a15ea27164c79977 338 PRINTS PR00412 Epoxide hydrolase signature 140 153 1.7E-13 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 LH59_19525 56c880ff4f3a7a38a15ea27164c79977 338 PRINTS PR00412 Epoxide hydrolase signature 72 90 1.7E-13 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 LH59_19525 56c880ff4f3a7a38a15ea27164c79977 338 PRINTS PR00412 Epoxide hydrolase signature 154 167 1.7E-13 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 LH59_19525 56c880ff4f3a7a38a15ea27164c79977 338 Gene3D G3DSA:3.40.50.1820 38 338 4.0E-79 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_04850 244f2b9f90fb0f2eb8e9c799810aa765 391 SUPERFAMILY SSF53901 251 373 1.08E-18 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_04850 244f2b9f90fb0f2eb8e9c799810aa765 391 PIRSF PIRSF000429 21 374 1.1E-12 T 14-10-2018 IPR002155 Thiolase GO:0016747 LH59_04850 244f2b9f90fb0f2eb8e9c799810aa765 391 Gene3D G3DSA:3.40.47.10 12 388 9.9E-80 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_04850 244f2b9f90fb0f2eb8e9c799810aa765 391 SUPERFAMILY SSF53901 33 233 3.69E-14 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 LH59_13810 922f2897a4911c53bc15644ee5b3e422 108 Gene3D G3DSA:1.10.10.10 1 96 3.2E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_13810 922f2897a4911c53bc15644ee5b3e422 108 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 2.9E-6 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LH59_13810 922f2897a4911c53bc15644ee5b3e422 108 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 2.9E-6 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LH59_13810 922f2897a4911c53bc15644ee5b3e422 108 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 2.9E-6 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LH59_13810 922f2897a4911c53bc15644ee5b3e422 108 SMART SM00418 8 89 1.4E-7 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 LH59_13810 922f2897a4911c53bc15644ee5b3e422 108 SUPERFAMILY SSF46785 3 93 1.82E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_13810 922f2897a4911c53bc15644ee5b3e422 108 Pfam PF12840 Helix-turn-helix domain 10 69 1.8E-14 T 14-10-2018 LH59_20560 ffe708246a1ef4598110d549385df1ee 101 Gene3D G3DSA:2.60.120.10 3 98 1.3E-17 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_20560 ffe708246a1ef4598110d549385df1ee 101 SUPERFAMILY SSF51182 4 90 1.78E-15 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_20560 ffe708246a1ef4598110d549385df1ee 101 Pfam PF07883 Cupin domain 37 91 5.1E-11 T 14-10-2018 IPR013096 Cupin 2, conserved barrel LH59_00875 a7b4d3102b86460d0b12b83f73d8bb77 284 Gene3D G3DSA:1.10.760.10 21 207 4.1E-16 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_00875 a7b4d3102b86460d0b12b83f73d8bb77 284 SUPERFAMILY SSF46626 20 248 1.32E-47 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_00875 a7b4d3102b86460d0b12b83f73d8bb77 284 Pfam PF02167 Cytochrome C1 family 35 282 4.0E-19 T 14-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 LH59_10590 f95f6e272ff1567d30616c180b1f3f30 114 TIGRFAM TIGR02683 upstrm_HI1419: putative addiction module killer protein 14 103 2.1E-32 T 14-10-2018 IPR014056 Addiction module killer protein, predicted LH59_10590 f95f6e272ff1567d30616c180b1f3f30 114 Pfam PF05973 Phage derived protein Gp49-like (DUF891) 49 92 1.7E-5 T 14-10-2018 IPR009241 Toxin HigB-like LH59_10590 f95f6e272ff1567d30616c180b1f3f30 114 PIRSF PIRSF028744 1 108 7.4E-37 T 14-10-2018 IPR014056 Addiction module killer protein, predicted LH59_18635 c5a1d87120d28311067fafd6cfb18cc9 269 Pfam PF12867 DinB superfamily 114 249 1.1E-6 T 14-10-2018 IPR024775 DinB-like domain LH59_18635 c5a1d87120d28311067fafd6cfb18cc9 269 SUPERFAMILY SSF109854 106 256 1.88E-19 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes LH59_18635 c5a1d87120d28311067fafd6cfb18cc9 269 Gene3D G3DSA:1.20.120.450 107 260 1.1E-20 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes LH59_11875 7fb49d715fbd1662def57ddef4f66369 258 Gene3D G3DSA:3.30.930.10 10 256 7.1E-58 T 14-10-2018 LH59_11875 7fb49d715fbd1662def57ddef4f66369 258 SUPERFAMILY SSF55681 4 254 3.55E-66 T 14-10-2018 LH59_11875 7fb49d715fbd1662def57ddef4f66369 258 Pfam PF03099 Biotin/lipoate A/B protein ligase family 66 172 1.4E-6 T 14-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 LH59_28110 8c6bd8ff42d6a0f940f5e5225bcdece9 270 Pfam PF00583 Acetyltransferase (GNAT) family 193 253 3.9E-10 T 14-10-2018 IPR000182 GNAT domain LH59_28110 8c6bd8ff42d6a0f940f5e5225bcdece9 270 SUPERFAMILY SSF55729 101 257 1.05E-19 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_28110 8c6bd8ff42d6a0f940f5e5225bcdece9 270 Gene3D G3DSA:3.40.630.30 17 263 4.4E-27 T 14-10-2018 LH59_16275 5d82bce588732537102ac92294fed617 256 SMART SM00849 23 208 7.8E-18 T 14-10-2018 IPR001279 Metallo-beta-lactamase LH59_16275 5d82bce588732537102ac92294fed617 256 Pfam PF00753 Metallo-beta-lactamase superfamily 24 194 3.5E-19 T 14-10-2018 IPR001279 Metallo-beta-lactamase LH59_16275 5d82bce588732537102ac92294fed617 256 Gene3D G3DSA:3.60.15.10 1 217 2.7E-44 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like LH59_16275 5d82bce588732537102ac92294fed617 256 SUPERFAMILY SSF56281 21 213 3.14E-37 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like LH59_05685 59c55017696d7223a68f99a8e90b05bc 186 Pfam PF13470 PIN domain 5 91 6.6E-11 T 14-10-2018 IPR002716 PIN domain LH59_15120 a1c18c5fa183b6dbd8331d2206e071fa 296 SUPERFAMILY SSF56317 14 286 2.49E-78 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily LH59_15120 a1c18c5fa183b6dbd8331d2206e071fa 296 Gene3D G3DSA:3.60.110.10 13 285 1.2E-90 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily LH59_15120 a1c18c5fa183b6dbd8331d2206e071fa 296 Pfam PF00795 Carbon-nitrogen hydrolase 16 267 4.8E-55 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 LH59_15570 7f3365eb8f32a56c3893e8df23cd6713 81 Pfam PF11903 ParD-like antitoxin of type II bacterial toxin-antitoxin system 1 68 2.6E-26 T 14-10-2018 IPR021831 ParD-like antitoxin of type II bacterial toxin-antitoxin system LH59_10020 27526ee1431da8c6938bfae032ed631e 86 SUPERFAMILY SSF47336 2 83 3.53E-18 T 14-10-2018 IPR036736 ACP-like superfamily LH59_10020 27526ee1431da8c6938bfae032ed631e 86 Pfam PF00550 Phosphopantetheine attachment site 10 75 6.3E-11 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain LH59_10020 27526ee1431da8c6938bfae032ed631e 86 Gene3D G3DSA:1.10.1200.10 1 86 3.0E-17 T 14-10-2018 IPR036736 ACP-like superfamily LH59_10020 27526ee1431da8c6938bfae032ed631e 86 ProSitePatterns PS00012 Phosphopantetheine attachment site. 35 50 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site LH59_05430 1db54fa5d0084fb2f60a05e9e45c59cd 598 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 2 598 35.31 T 14-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 LH59_05430 1db54fa5d0084fb2f60a05e9e45c59cd 598 PIRSF PIRSF001294 1 598 2.1E-234 T 14-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 LH59_05430 1db54fa5d0084fb2f60a05e9e45c59cd 598 Pfam PF03814 Potassium-transporting ATPase A subunit 11 596 2.1E-239 T 14-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 LH59_05430 1db54fa5d0084fb2f60a05e9e45c59cd 598 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 244 597 6.7E-152 T 14-10-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 LH59_22140 b08accbb94b3897c9b61921af8c40fa5 540 Pfam PF00501 AMP-binding enzyme 12 433 1.4E-93 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 LH59_22140 b08accbb94b3897c9b61921af8c40fa5 540 Gene3D G3DSA:3.30.300.310 430 533 1.6E-28 T 14-10-2018 LH59_22140 b08accbb94b3897c9b61921af8c40fa5 540 Pfam PF13193 AMP-binding enzyme C-terminal domain 442 512 6.7E-17 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain LH59_22140 b08accbb94b3897c9b61921af8c40fa5 540 SUPERFAMILY SSF56801 5 532 2.09E-140 T 14-10-2018 LH59_22140 b08accbb94b3897c9b61921af8c40fa5 540 ProSitePatterns PS00455 Putative AMP-binding domain signature. 187 198 - T 14-10-2018 IPR020845 AMP-binding, conserved site LH59_22140 b08accbb94b3897c9b61921af8c40fa5 540 Gene3D G3DSA:3.40.50.12780 2 429 3.3E-105 T 14-10-2018 LH59_11280 5675d96b799a8030eca825c1549b2829 67 Gene3D G3DSA:1.20.58.1830 32 66 5.3E-35 T 14-10-2018 LH59_11280 5675d96b799a8030eca825c1549b2829 67 Pfam PF00700 Bacterial flagellin C-terminal helical region 1 66 1.1E-24 T 14-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 LH59_11280 5675d96b799a8030eca825c1549b2829 67 Gene3D G3DSA:1.20.1330.10 1 26 5.3E-35 T 14-10-2018 LH59_11280 5675d96b799a8030eca825c1549b2829 67 SUPERFAMILY SSF64518 1 67 1.57E-26 T 14-10-2018 LH59_01965 dfe40aec6830754c486680174c70bb14 234 Pfam PF01144 Coenzyme A transferase 10 205 1.8E-31 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 LH59_01965 dfe40aec6830754c486680174c70bb14 234 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 8 213 4.6E-83 T 14-10-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 LH59_01965 dfe40aec6830754c486680174c70bb14 234 Gene3D G3DSA:3.40.1080.10 5 217 1.8E-78 T 14-10-2018 LH59_01965 dfe40aec6830754c486680174c70bb14 234 SMART SM00882 10 207 1.6E-56 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 LH59_01965 dfe40aec6830754c486680174c70bb14 234 SUPERFAMILY SSF100950 8 218 1.02E-57 T 14-10-2018 IPR037171 NagB/RpiA transferase-like LH59_20170 509984e93b0918d125d04a653d022cac 199 SMART SM00530 134 189 2.8E-7 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LH59_20170 509984e93b0918d125d04a653d022cac 199 SUPERFAMILY SSF47413 134 189 2.36E-10 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 LH59_20170 509984e93b0918d125d04a653d022cac 199 Gene3D G3DSA:1.10.260.40 133 192 3.0E-10 T 14-10-2018 LH59_20170 509984e93b0918d125d04a653d022cac 199 Pfam PF01381 Helix-turn-helix 135 189 4.0E-8 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LH59_18290 784f00ec566f8900d176cf8231128c2f 191 SUPERFAMILY SSF55729 20 180 2.7E-38 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_18290 784f00ec566f8900d176cf8231128c2f 191 Pfam PF13302 Acetyltransferase (GNAT) domain 20 156 7.0E-26 T 14-10-2018 IPR000182 GNAT domain LH59_18290 784f00ec566f8900d176cf8231128c2f 191 Gene3D G3DSA:3.40.630.30 11 184 1.8E-40 T 14-10-2018 LH59_20750 0dab35bb7bfd850a20141f4780d3185e 723 SUPERFAMILY SSF56935 30 723 3.21E-107 T 14-10-2018 LH59_20750 0dab35bb7bfd850a20141f4780d3185e 723 TIGRFAM TIGR01783 TonB-siderophor: TonB-dependent siderophore receptor 80 723 6.6E-99 T 14-10-2018 IPR010105 TonB-dependent siderophore receptor GO:0005506|GO:0015891|GO:0038023 LH59_20750 0dab35bb7bfd850a20141f4780d3185e 723 Pfam PF07715 TonB-dependent Receptor Plug Domain 78 176 1.9E-17 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain LH59_20750 0dab35bb7bfd850a20141f4780d3185e 723 Gene3D G3DSA:2.40.170.20 191 723 5.6E-77 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily LH59_20750 0dab35bb7bfd850a20141f4780d3185e 723 Gene3D G3DSA:2.170.130.10 68 190 7.6E-27 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily LH59_20750 0dab35bb7bfd850a20141f4780d3185e 723 Pfam PF00593 TonB dependent receptor 294 721 1.6E-38 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel LH59_04095 0cbefe687c24e3d1c5b7cf9f912fb8cd 239 Pfam PF13468 Glyoxalase-like domain 10 184 6.3E-32 T 14-10-2018 IPR025870 Glyoxalase-like domain LH59_04095 0cbefe687c24e3d1c5b7cf9f912fb8cd 239 Gene3D G3DSA:3.10.180.10 7 152 2.1E-5 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_04095 0cbefe687c24e3d1c5b7cf9f912fb8cd 239 SUPERFAMILY SSF54593 6 107 7.62E-9 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_23035 9468f5d96ab5cc3ffc001f9658f51d83 322 PIRSF PIRSF017082 2 321 2.3E-66 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_23035 9468f5d96ab5cc3ffc001f9658f51d83 322 Gene3D G3DSA:3.40.190.10 125 248 1.8E-101 T 14-10-2018 LH59_23035 9468f5d96ab5cc3ffc001f9658f51d83 322 Gene3D G3DSA:3.40.190.150 28 313 1.8E-101 T 14-10-2018 LH59_23035 9468f5d96ab5cc3ffc001f9658f51d83 322 SUPERFAMILY SSF53850 113 283 1.52E-8 T 14-10-2018 LH59_23035 9468f5d96ab5cc3ffc001f9658f51d83 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 316 1.2E-73 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_25695 5619e6cb34bfa564ad8905d0f17d85e0 271 Gene3D G3DSA:3.40.50.80 137 271 6.5E-43 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain LH59_25695 5619e6cb34bfa564ad8905d0f17d85e0 271 Pfam PF08021 Siderophore-interacting FAD-binding domain 21 135 2.0E-37 T 14-10-2018 IPR013113 FAD-binding 9, siderophore-interacting LH59_25695 5619e6cb34bfa564ad8905d0f17d85e0 271 SUPERFAMILY SSF63380 10 139 3.97E-15 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel LH59_25695 5619e6cb34bfa564ad8905d0f17d85e0 271 Gene3D G3DSA:2.40.30.10 2 136 4.5E-45 T 14-10-2018 LH59_25695 5619e6cb34bfa564ad8905d0f17d85e0 271 Pfam PF04954 Siderophore-interacting protein 143 261 1.5E-39 T 14-10-2018 IPR007037 Siderophore-interacting protein, C-terminal domain LH59_03135 ed6d2affc90b8256ee90aaf09944c9b8 365 Pfam PF13416 Bacterial extracellular solute-binding protein 62 323 1.0E-20 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein LH59_03135 ed6d2affc90b8256ee90aaf09944c9b8 365 Gene3D G3DSA:3.40.190.10 48 347 3.0E-116 T 14-10-2018 LH59_03135 ed6d2affc90b8256ee90aaf09944c9b8 365 SUPERFAMILY SSF53850 47 344 3.39E-56 T 14-10-2018 LH59_03135 ed6d2affc90b8256ee90aaf09944c9b8 365 Gene3D G3DSA:3.40.190.10 145 360 3.0E-116 T 14-10-2018 LH59_03150 5fcedff6e115ff84334b99ff604301ee 635 Pfam PF00773 RNB domain 474 514 5.8E-9 T 14-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 LH59_03150 5fcedff6e115ff84334b99ff604301ee 635 SMART SM00955 235 516 9.9E-61 T 14-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 LH59_03150 5fcedff6e115ff84334b99ff604301ee 635 SUPERFAMILY SSF50249 230 566 5.6E-73 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_03150 5fcedff6e115ff84334b99ff604301ee 635 Pfam PF00773 RNB domain 238 470 9.6E-35 T 14-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 LH59_20785 0f1dded9c04e70567a69d565d2c63d94 205 Pfam PF01810 LysE type translocator 16 202 3.2E-36 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 LH59_20785 0f1dded9c04e70567a69d565d2c63d94 205 PIRSF PIRSF006324 1 205 4.4E-51 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 LH59_08500 aaac04ad7bd41b38848440612f476d44 226 Gene3D G3DSA:2.60.120.620 1 178 6.2E-42 T 14-10-2018 LH59_08500 aaac04ad7bd41b38848440612f476d44 226 Hamap MF_00657 PKHD-type hydroxylase YbiX [ybiX]. 1 226 45.739 T 14-10-2018 IPR023550 PKHD-type hydroxylase GO:0016706|GO:0055114 LH59_08500 aaac04ad7bd41b38848440612f476d44 226 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 84 176 3.7E-13 T 14-10-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 LH59_08500 aaac04ad7bd41b38848440612f476d44 226 Gene3D G3DSA:4.10.860.20 180 226 1.6E-19 T 14-10-2018 LH59_08500 aaac04ad7bd41b38848440612f476d44 226 SMART SM00702 1 177 1.4E-26 T 14-10-2018 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 LH59_08095 2ac38273a31679e238b5908986426d01 43 Pfam PF08085 Entericidin EcnA/B family 21 41 2.1E-10 T 14-10-2018 IPR012556 Entericidin A/B GO:0009636|GO:0016020 LH59_11540 6ea74bf445c4ceef43593fa3108067d5 265 Gene3D G3DSA:2.40.10.220 126 217 4.5E-14 T 14-10-2018 LH59_15475 15ce88b4a08c8ebffc94760a3cc6dbfe 448 Pfam PF05936 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE 19 446 8.6E-139 T 14-10-2018 IPR010263 Type VI secretion protein, VC_A0114 LH59_15475 15ce88b4a08c8ebffc94760a3cc6dbfe 448 TIGRFAM TIGR03353 VI_chp_4: type VI secretion protein, VC_A0114 family 6 447 3.1E-141 T 14-10-2018 IPR010263 Type VI secretion protein, VC_A0114 LH59_15595 f50a8e2b2e2c49f760dceb580f9b348b 446 Pfam PF04286 Protein of unknown function (DUF445) 67 442 6.0E-104 T 14-10-2018 IPR007383 Protein of unknown function DUF445 LH59_05210 c17c5e2cbbd5c05cd0b871f24f6c6a24 150 Pfam PF12680 SnoaL-like domain 35 132 3.8E-17 T 14-10-2018 IPR037401 SnoaL-like domain LH59_05210 c17c5e2cbbd5c05cd0b871f24f6c6a24 150 SUPERFAMILY SSF54427 30 140 9.56E-27 T 14-10-2018 IPR032710 NTF2-like domain superfamily LH59_05210 c17c5e2cbbd5c05cd0b871f24f6c6a24 150 Gene3D G3DSA:3.10.450.50 24 150 4.7E-43 T 14-10-2018 LH59_18310 7fc7bbbb8da4178f895bb7e26da93fa0 322 Gene3D G3DSA:3.40.190.150 26 312 2.3E-115 T 14-10-2018 LH59_18310 7fc7bbbb8da4178f895bb7e26da93fa0 322 Gene3D G3DSA:3.40.190.10 124 247 2.3E-115 T 14-10-2018 LH59_18310 7fc7bbbb8da4178f895bb7e26da93fa0 322 PIRSF PIRSF017082 1 321 4.1E-88 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_18310 7fc7bbbb8da4178f895bb7e26da93fa0 322 SUPERFAMILY SSF53850 109 282 4.46E-19 T 14-10-2018 LH59_18310 7fc7bbbb8da4178f895bb7e26da93fa0 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 317 2.1E-94 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_10970 91ee07768602752fa7c2b6eceeb998a1 170 SUPERFAMILY SSF88659 89 162 3.74E-13 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like LH59_10970 91ee07768602752fa7c2b6eceeb998a1 170 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 161 6.2E-24 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 LH59_10970 91ee07768602752fa7c2b6eceeb998a1 170 Pfam PF04542 Sigma-70 region 2 15 79 3.0E-14 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 LH59_10970 91ee07768602752fa7c2b6eceeb998a1 170 Gene3D G3DSA:1.10.10.10 106 169 1.7E-13 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_10970 91ee07768602752fa7c2b6eceeb998a1 170 Pfam PF08281 Sigma-70, region 4 111 159 1.3E-14 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LH59_10970 91ee07768602752fa7c2b6eceeb998a1 170 SUPERFAMILY SSF88946 12 100 2.47E-14 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 LH59_10970 91ee07768602752fa7c2b6eceeb998a1 170 Gene3D G3DSA:1.10.1740.10 3 80 2.7E-7 T 14-10-2018 LH59_12320 50634745b7a5ed8c5c42793e68a96212 195 SUPERFAMILY SSF54980 129 192 7.91E-10 T 14-10-2018 IPR035647 EF-G domain III/V-like LH59_12320 50634745b7a5ed8c5c42793e68a96212 195 Gene3D G3DSA:3.30.230.30 1 125 1.7E-48 T 14-10-2018 IPR036956 Impact, N-terminal domain superfamily LH59_12320 50634745b7a5ed8c5c42793e68a96212 195 Pfam PF01205 Uncharacterized protein family UPF0029 16 116 2.4E-30 T 14-10-2018 IPR001498 Impact, N-terminal LH59_12320 50634745b7a5ed8c5c42793e68a96212 195 SUPERFAMILY SSF54211 4 122 8.72E-41 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold LH59_12320 50634745b7a5ed8c5c42793e68a96212 195 Pfam PF09186 Domain of unknown function (DUF1949) 132 188 2.6E-10 T 14-10-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal LH59_12320 50634745b7a5ed8c5c42793e68a96212 195 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 71 100 - T 14-10-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site LH59_23140 4c3a9b27540de6ac188844c548224c32 624 Pfam PF07730 Histidine kinase 424 474 9.6E-5 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 LH59_23140 4c3a9b27540de6ac188844c548224c32 624 SUPERFAMILY SSF55874 490 608 6.6E-10 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_23140 4c3a9b27540de6ac188844c548224c32 624 Gene3D G3DSA:3.30.565.10 494 618 2.5E-21 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_23140 4c3a9b27540de6ac188844c548224c32 624 SMART SM00387 524 621 3.0E-5 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_23140 4c3a9b27540de6ac188844c548224c32 624 Pfam PF07695 7TM diverse intracellular signalling 189 369 2.4E-10 T 14-10-2018 IPR011623 7TM-DISM receptor, extracellular domain, type 1 LH59_23140 4c3a9b27540de6ac188844c548224c32 624 SUPERFAMILY SSF49785 44 149 3.23E-6 T 14-10-2018 IPR008979 Galactose-binding-like domain superfamily LH59_04395 ae8cafe8e434262c7f985a68eedfbdf2 409 Pfam PF07670 Nucleoside recognition 276 379 1.4E-5 T 14-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 LH59_04395 ae8cafe8e434262c7f985a68eedfbdf2 409 Pfam PF07670 Nucleoside recognition 52 158 3.3E-8 T 14-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 LH59_04395 ae8cafe8e434262c7f985a68eedfbdf2 409 PIRSF PIRSF036542 1 409 2.2E-208 T 14-10-2018 IPR011415 Predicted bifunctional spore maturation protein, fused SpmA/SpmB LH59_11885 e6dd884957ebc1f6726daeb534f67b3d 154 Pfam PF00583 Acetyltransferase (GNAT) family 38 143 4.6E-17 T 14-10-2018 IPR000182 GNAT domain LH59_11885 e6dd884957ebc1f6726daeb534f67b3d 154 SUPERFAMILY SSF55729 2 148 4.97E-29 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_11885 e6dd884957ebc1f6726daeb534f67b3d 154 Gene3D G3DSA:3.40.630.30 5 154 1.9E-39 T 14-10-2018 LH59_16845 610125e6fad5f8e1e34937069435a804 1144 Pfam PF13018 Extended Signal Peptide of Type V secretion system 2 23 1.1E-7 T 14-10-2018 IPR024973 ESPR domain LH59_16845 610125e6fad5f8e1e34937069435a804 1144 SUPERFAMILY SSF51126 421 723 4.39E-29 T 14-10-2018 IPR011050 Pectin lyase fold/virulence factor LH59_16845 610125e6fad5f8e1e34937069435a804 1144 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 654 1143 1.5E-42 T 14-10-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 LH59_16845 610125e6fad5f8e1e34937069435a804 1144 Pfam PF12951 Passenger-associated-transport-repeat 582 611 2.3E-8 T 14-10-2018 IPR013425 Autotransporter-associated beta strand repeat LH59_16845 610125e6fad5f8e1e34937069435a804 1144 Pfam PF12951 Passenger-associated-transport-repeat 515 542 7.6E-9 T 14-10-2018 IPR013425 Autotransporter-associated beta strand repeat LH59_16845 610125e6fad5f8e1e34937069435a804 1144 Pfam PF12951 Passenger-associated-transport-repeat 446 472 5.7E-6 T 14-10-2018 IPR013425 Autotransporter-associated beta strand repeat LH59_16845 610125e6fad5f8e1e34937069435a804 1144 SUPERFAMILY SSF51126 94 551 5.02E-5 T 14-10-2018 IPR011050 Pectin lyase fold/virulence factor LH59_16845 610125e6fad5f8e1e34937069435a804 1144 SUPERFAMILY SSF103515 810 1143 5.89E-60 T 14-10-2018 IPR036709 Autotransporter beta-domain superfamily LH59_16845 610125e6fad5f8e1e34937069435a804 1144 SMART SM00869 866 1134 2.1E-42 T 14-10-2018 IPR005546 Autotransporter beta-domain LH59_16845 610125e6fad5f8e1e34937069435a804 1144 Gene3D G3DSA:2.40.128.130 802 1144 1.3E-70 T 14-10-2018 IPR036709 Autotransporter beta-domain superfamily LH59_16845 610125e6fad5f8e1e34937069435a804 1144 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 582 612 1.9E-10 T 14-10-2018 IPR013425 Autotransporter-associated beta strand repeat LH59_16845 610125e6fad5f8e1e34937069435a804 1144 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 516 543 2.6E-9 T 14-10-2018 IPR013425 Autotransporter-associated beta strand repeat LH59_16845 610125e6fad5f8e1e34937069435a804 1144 TIGRFAM TIGR02601 autotrns_rpt: autotransporter-associated beta strand repeat 442 473 1.2E-5 T 14-10-2018 IPR013425 Autotransporter-associated beta strand repeat LH59_16845 610125e6fad5f8e1e34937069435a804 1144 Pfam PF03797 Autotransporter beta-domain 869 1123 5.4E-57 T 14-10-2018 IPR005546 Autotransporter beta-domain LH59_03630 4e10e13e40dfb7054b3e0b4d13b0ec57 500 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 210 488 3.6E-62 T 14-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family LH59_03630 4e10e13e40dfb7054b3e0b4d13b0ec57 500 SUPERFAMILY SSF53850 210 489 2.5E-56 T 14-10-2018 LH59_03630 4e10e13e40dfb7054b3e0b4d13b0ec57 500 Gene3D G3DSA:3.40.190.10 211 488 5.0E-67 T 14-10-2018 LH59_03630 4e10e13e40dfb7054b3e0b4d13b0ec57 500 Gene3D G3DSA:3.40.190.10 293 431 5.0E-67 T 14-10-2018 LH59_03630 4e10e13e40dfb7054b3e0b4d13b0ec57 500 Pfam PF16868 NMT1-like family 227 488 6.0E-56 T 14-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family LH59_19815 0a0118dd456e1056589ef27cb1782b61 317 Pfam PF08666 SAF domain 57 116 2.7E-10 T 14-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 LH59_19815 0a0118dd456e1056589ef27cb1782b61 317 SMART SM00858 56 117 4.4E-10 T 14-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 LH59_19815 0a0118dd456e1056589ef27cb1782b61 317 TIGRFAM TIGR03177 pilus_cpaB: Flp pilus assembly protein CpaB 11 314 8.0E-49 T 14-10-2018 IPR017592 Pilus assembly, Flp-type CpaB LH59_19815 0a0118dd456e1056589ef27cb1782b61 317 Pfam PF16976 Flp pilus assembly protein RcpC/CpaB 119 231 1.0E-27 T 14-10-2018 IPR031571 Flp pilus assembly protein RcpC/CpaB domain LH59_23815 73eb14434782a90c86e8913d8252478b 422 Pfam PF08376 Nitrate and nitrite sensing 39 281 1.7E-39 T 14-10-2018 IPR013587 Nitrate/nitrite sensing protein LH59_23815 73eb14434782a90c86e8913d8252478b 422 Gene3D G3DSA:1.10.10.10 361 420 1.2E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_23815 73eb14434782a90c86e8913d8252478b 422 Pfam PF03861 ANTAR domain 364 414 7.1E-18 T 14-10-2018 IPR005561 ANTAR domain GO:0003723 LH59_23815 73eb14434782a90c86e8913d8252478b 422 SUPERFAMILY SSF52172 341 414 1.09E-12 T 14-10-2018 IPR011006 CheY-like superfamily LH59_23815 73eb14434782a90c86e8913d8252478b 422 SMART SM01012 359 414 2.8E-16 T 14-10-2018 IPR005561 ANTAR domain GO:0003723 LH59_18470 68c0bf00690394aa25bf70f22c7247c6 316 Gene3D G3DSA:3.40.190.10 120 241 7.2E-94 T 14-10-2018 LH59_18470 68c0bf00690394aa25bf70f22c7247c6 316 Gene3D G3DSA:3.40.190.150 22 305 7.2E-94 T 14-10-2018 LH59_18470 68c0bf00690394aa25bf70f22c7247c6 316 SUPERFAMILY SSF53850 103 279 4.44E-13 T 14-10-2018 LH59_18470 68c0bf00690394aa25bf70f22c7247c6 316 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 41 313 5.5E-66 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_18470 68c0bf00690394aa25bf70f22c7247c6 316 PIRSF PIRSF017082 1 316 8.3E-70 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_20185 0d6612ee772da43cf961f4065388efa7 198 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 161 3.0E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_20185 0d6612ee772da43cf961f4065388efa7 198 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 3.0E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_20185 0d6612ee772da43cf961f4065388efa7 198 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 54 65 3.0E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_20185 0d6612ee772da43cf961f4065388efa7 198 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 144 3.0E-9 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_20185 0d6612ee772da43cf961f4065388efa7 198 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 24 159 7.6E-14 T 14-10-2018 LH59_20185 0d6612ee772da43cf961f4065388efa7 198 SUPERFAMILY SSF51735 3 183 9.13E-24 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_20185 0d6612ee772da43cf961f4065388efa7 198 Gene3D G3DSA:3.40.50.720 2 198 1.0E-39 T 14-10-2018 LH59_15295 e633e7752ca13e98e70c098a4106710e 399 Pfam PF07690 Major Facilitator Superfamily 24 337 3.7E-28 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_15295 e633e7752ca13e98e70c098a4106710e 399 SUPERFAMILY SSF103473 10 393 4.58E-45 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_15295 e633e7752ca13e98e70c098a4106710e 399 Gene3D G3DSA:1.20.1250.20 11 192 6.8E-21 T 14-10-2018 LH59_15295 e633e7752ca13e98e70c098a4106710e 399 Gene3D G3DSA:1.20.1250.20 215 394 1.8E-19 T 14-10-2018 LH59_08205 60ef5ada5cf3d5f620465a7d3c00d313 329 SUPERFAMILY SSF53850 118 286 5.97E-9 T 14-10-2018 LH59_08205 60ef5ada5cf3d5f620465a7d3c00d313 329 PIRSF PIRSF017082 1 328 3.0E-80 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_08205 60ef5ada5cf3d5f620465a7d3c00d313 329 Gene3D G3DSA:3.40.190.150 33 319 8.9E-114 T 14-10-2018 LH59_08205 60ef5ada5cf3d5f620465a7d3c00d313 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 325 2.4E-86 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_08205 60ef5ada5cf3d5f620465a7d3c00d313 329 Gene3D G3DSA:3.40.190.10 131 254 8.9E-114 T 14-10-2018 LH59_10425 7dad85647a94746cbf470f9b5875a06d 258 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 161 187 8.2E-38 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 LH59_10425 7dad85647a94746cbf470f9b5875a06d 258 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 105 125 8.2E-38 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 LH59_10425 7dad85647a94746cbf470f9b5875a06d 258 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 50 67 8.2E-38 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 LH59_10425 7dad85647a94746cbf470f9b5875a06d 258 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 67 87 8.2E-38 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 LH59_10425 7dad85647a94746cbf470f9b5875a06d 258 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 126 146 8.2E-38 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 LH59_10425 7dad85647a94746cbf470f9b5875a06d 258 Pfam PF01578 Cytochrome C assembly protein 36 189 1.3E-23 T 14-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 LH59_10425 7dad85647a94746cbf470f9b5875a06d 258 TIGRFAM TIGR01191 ccmC: heme exporter protein CcmC 50 232 2.2E-59 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 LH59_02525 adae97a9a74311fa80742119d1cc1234 280 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 16 276 3.4E-92 T 14-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 LH59_02525 adae97a9a74311fa80742119d1cc1234 280 Pfam PF08543 Phosphomethylpyrimidine kinase 23 274 5.7E-91 T 14-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 LH59_02525 adae97a9a74311fa80742119d1cc1234 280 SUPERFAMILY SSF53613 13 279 5.46E-78 T 14-10-2018 IPR029056 Ribokinase-like LH59_02525 adae97a9a74311fa80742119d1cc1234 280 Gene3D G3DSA:3.40.1190.20 2 280 8.3E-103 T 14-10-2018 IPR029056 Ribokinase-like LH59_09995 e5c968299774dce49ac49dc608477074 198 Gene3D G3DSA:2.50.20.10 21 192 1.1E-16 T 14-10-2018 LH59_09995 e5c968299774dce49ac49dc608477074 198 SUPERFAMILY SSF89392 22 182 1.1E-8 T 14-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX LH59_06325 98d76ba282a8544d6f1b30bf06448d2f 281 Pfam PF01063 Amino-transferase class IV 32 252 4.8E-39 T 14-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 LH59_06325 98d76ba282a8544d6f1b30bf06448d2f 281 Gene3D G3DSA:3.20.10.10 126 281 4.0E-39 T 14-10-2018 LH59_06325 98d76ba282a8544d6f1b30bf06448d2f 281 SUPERFAMILY SSF56752 4 276 3.14E-71 T 14-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 LH59_06325 98d76ba282a8544d6f1b30bf06448d2f 281 Gene3D G3DSA:3.30.470.10 1 123 1.3E-28 T 14-10-2018 LH59_12060 38f8bdbd3af087f5f46df3de6f7338ac 204 SUPERFAMILY SSF109604 26 196 9.14E-33 T 14-10-2018 LH59_12060 38f8bdbd3af087f5f46df3de6f7338ac 204 TIGRFAM TIGR00277 HDIG: HDIG domain 33 125 1.5E-7 T 14-10-2018 IPR006675 HDIG domain LH59_12060 38f8bdbd3af087f5f46df3de6f7338ac 204 SMART SM00471 29 166 2.5E-6 T 14-10-2018 IPR003607 HD/PDEase domain LH59_12060 38f8bdbd3af087f5f46df3de6f7338ac 204 Gene3D G3DSA:1.10.3210.10 13 200 6.5E-61 T 14-10-2018 LH59_12060 38f8bdbd3af087f5f46df3de6f7338ac 204 Pfam PF01966 HD domain 35 156 1.0E-20 T 14-10-2018 IPR006674 HD domain LH59_09340 d3f394889d8704fd1a0855865066237f 495 Pfam PF02696 Uncharacterized ACR, YdiU/UPF0061 family 12 464 1.9E-134 T 14-10-2018 IPR003846 Uncharacterised protein family UPF0061 LH59_09340 d3f394889d8704fd1a0855865066237f 495 Hamap MF_00692 UPF0061 protein YdiU [ydiU]. 7 481 43.854 T 14-10-2018 IPR003846 Uncharacterised protein family UPF0061 LH59_25660 cd282782ef808832dcd0e8fc5b04761b 126 SUPERFAMILY SSF51182 38 116 1.09E-13 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_25660 cd282782ef808832dcd0e8fc5b04761b 126 Gene3D G3DSA:2.60.120.10 39 117 5.9E-15 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_25660 cd282782ef808832dcd0e8fc5b04761b 126 Pfam PF07883 Cupin domain 54 115 1.5E-9 T 14-10-2018 IPR013096 Cupin 2, conserved barrel LH59_25680 283d94e45bc71723d36d9414a8d350db 958 Pfam PF14903 WG containing repeat 91 125 4.4E-9 T 14-10-2018 IPR032774 WG containing repeat LH59_25680 283d94e45bc71723d36d9414a8d350db 958 Pfam PF14903 WG containing repeat 125 160 2.4E-10 T 14-10-2018 IPR032774 WG containing repeat LH59_25680 283d94e45bc71723d36d9414a8d350db 958 Pfam PF14903 WG containing repeat 595 626 0.063 T 14-10-2018 IPR032774 WG containing repeat LH59_25680 283d94e45bc71723d36d9414a8d350db 958 SUPERFAMILY SSF69360 90 172 2.35E-5 T 14-10-2018 LH59_25600 fdf56c0ca28d75b452f233d7deecc705 242 Pfam PF05100 Phage minor tail protein L 25 239 2.2E-73 T 14-10-2018 IPR006487 Bacteriophage lambda, GpL, minor tail LH59_25600 fdf56c0ca28d75b452f233d7deecc705 242 TIGRFAM TIGR01600 phage_tail_L: phage minor tail protein L 6 239 4.2E-89 T 14-10-2018 IPR006487 Bacteriophage lambda, GpL, minor tail LH59_27210 02bd61e906f53b322747d6d1f32237c2 335 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 29 86 2.6E-8 T 14-10-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 LH59_27210 02bd61e906f53b322747d6d1f32237c2 335 Pfam PF04055 Radical SAM superfamily 104 263 1.9E-13 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 LH59_27210 02bd61e906f53b322747d6d1f32237c2 335 Hamap MF_00206 Lipoyl synthase [lipA]. 49 335 154.079 T 14-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 LH59_27210 02bd61e906f53b322747d6d1f32237c2 335 Gene3D G3DSA:3.20.20.70 95 300 9.2E-20 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_27210 02bd61e906f53b322747d6d1f32237c2 335 SMART SM00729 97 306 5.4E-15 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 LH59_27210 02bd61e906f53b322747d6d1f32237c2 335 SUPERFAMILY SSF102114 65 330 1.31E-66 T 14-10-2018 LH59_27210 02bd61e906f53b322747d6d1f32237c2 335 PIRSF PIRSF005963 2 334 1.4E-129 T 14-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 LH59_27210 02bd61e906f53b322747d6d1f32237c2 335 TIGRFAM TIGR00510 lipA: lipoyl synthase 46 328 8.2E-130 T 14-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 LH59_28140 edfd6fde87ec0f398d790c58077479bb 388 Gene3D G3DSA:3.40.640.10 40 282 4.8E-133 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_28140 edfd6fde87ec0f398d790c58077479bb 388 Gene3D G3DSA:3.90.1150.10 12 381 4.8E-133 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_28140 edfd6fde87ec0f398d790c58077479bb 388 SUPERFAMILY SSF53383 3 388 2.93E-100 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_28140 edfd6fde87ec0f398d790c58077479bb 388 Pfam PF00155 Aminotransferase class I and II 26 385 2.6E-57 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LH59_27265 3608d45a8e575f38b51d0dd907f7f2f0 377 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 139 374 4.2E-66 T 14-10-2018 IPR003453 ABC transport permease subunit MlaE, Proteobacteria LH59_27265 3608d45a8e575f38b51d0dd907f7f2f0 377 Pfam PF02405 Permease MlaE 161 370 1.8E-66 T 14-10-2018 IPR030802 ABC transporter permease MalE GO:0043190 LH59_12075 7d71eac39e0888df6d66d0f05a1f15af 361 Gene3D G3DSA:2.40.50.140 288 332 4.2E-5 T 14-10-2018 LH59_12075 7d71eac39e0888df6d66d0f05a1f15af 361 SUPERFAMILY SSF50331 234 347 1.83E-17 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal LH59_12075 7d71eac39e0888df6d66d0f05a1f15af 361 SMART SM00382 27 207 1.4E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_12075 7d71eac39e0888df6d66d0f05a1f15af 361 Pfam PF08402 TOBE domain 271 341 3.8E-5 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 LH59_12075 7d71eac39e0888df6d66d0f05a1f15af 361 SUPERFAMILY SSF52540 10 239 4.36E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_12075 7d71eac39e0888df6d66d0f05a1f15af 361 Gene3D G3DSA:3.40.50.300 1 233 2.2E-54 T 14-10-2018 LH59_12075 7d71eac39e0888df6d66d0f05a1f15af 361 Gene3D G3DSA:2.40.50.100 236 341 4.2E-5 T 14-10-2018 LH59_12075 7d71eac39e0888df6d66d0f05a1f15af 361 Pfam PF00005 ABC transporter 21 158 2.8E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_12075 7d71eac39e0888df6d66d0f05a1f15af 361 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_16760 818e476495e650ad94c54bc8f76a818a 474 Pfam PF00355 Rieske [2Fe-2S] domain 50 131 1.3E-15 T 14-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 LH59_16760 818e476495e650ad94c54bc8f76a818a 474 Gene3D G3DSA:2.102.10.10 46 176 4.6E-33 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 LH59_16760 818e476495e650ad94c54bc8f76a818a 474 SUPERFAMILY SSF50022 43 159 1.27E-32 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 LH59_16760 818e476495e650ad94c54bc8f76a818a 474 SUPERFAMILY SSF55961 151 413 1.81E-28 T 14-10-2018 LH59_16760 818e476495e650ad94c54bc8f76a818a 474 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 91 113 - T 14-10-2018 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0051537|GO:0055114 LH59_24930 58c31f72ea96881d86a5f4e42243ea1c 271 SUPERFAMILY SSF46894 151 236 8.5E-12 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LH59_24930 58c31f72ea96881d86a5f4e42243ea1c 271 Pfam PF00486 Transcriptional regulatory protein, C terminal 158 234 1.3E-7 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_24930 58c31f72ea96881d86a5f4e42243ea1c 271 SUPERFAMILY SSF52172 18 123 2.56E-9 T 14-10-2018 IPR011006 CheY-like superfamily LH59_24930 58c31f72ea96881d86a5f4e42243ea1c 271 Gene3D G3DSA:1.10.10.10 136 239 1.1E-11 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_24930 58c31f72ea96881d86a5f4e42243ea1c 271 Gene3D G3DSA:3.40.50.2300 8 123 1.2E-6 T 14-10-2018 LH59_24930 58c31f72ea96881d86a5f4e42243ea1c 271 SMART SM00862 157 234 7.5E-9 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_23600 4c389092fba23a7eaf25399f616ece2b 209 Pfam PF14300 Domain of unknown function (DUF4375) 97 209 6.9E-18 T 14-10-2018 IPR025402 Domain of unknown function DUF4375 LH59_23600 4c389092fba23a7eaf25399f616ece2b 209 Pfam PF10387 Protein of unknown function (DUF2442) 14 62 1.5E-5 T 14-10-2018 IPR018841 Protein of unknown function DUF2442 LH59_01195 46b2dadd6601fd096605d1466d2ed11c 457 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 3 456 1.0E-189 T 14-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 LH59_01195 46b2dadd6601fd096605d1466d2ed11c 457 SUPERFAMILY SSF51161 256 438 3.79E-49 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily LH59_01195 46b2dadd6601fd096605d1466d2ed11c 457 SUPERFAMILY SSF53448 2 253 4.59E-61 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases LH59_01195 46b2dadd6601fd096605d1466d2ed11c 457 Gene3D G3DSA:3.90.550.10 1 228 2.3E-62 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases LH59_01195 46b2dadd6601fd096605d1466d2ed11c 457 Pfam PF12804 MobA-like NTP transferase domain 4 129 2.9E-23 T 14-10-2018 IPR025877 MobA-like NTP transferase LH59_01195 46b2dadd6601fd096605d1466d2ed11c 457 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 1 453 42.866 T 14-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 LH59_01195 46b2dadd6601fd096605d1466d2ed11c 457 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 268 300 9.6E-5 T 14-10-2018 IPR001451 Hexapeptide repeat LH59_01195 46b2dadd6601fd096605d1466d2ed11c 457 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 320 353 1.2E-5 T 14-10-2018 IPR001451 Hexapeptide repeat LH59_01195 46b2dadd6601fd096605d1466d2ed11c 457 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 396 430 1.2E-6 T 14-10-2018 IPR001451 Hexapeptide repeat LH59_01195 46b2dadd6601fd096605d1466d2ed11c 457 Gene3D G3DSA:2.160.10.10 229 457 3.0E-64 T 14-10-2018 LH59_01195 46b2dadd6601fd096605d1466d2ed11c 457 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 327 355 - T 14-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 LH59_01625 d2ada2a73cc3a4555656c4fefa4ef921 268 Pfam PF03180 NLPA lipoprotein 31 268 1.6E-84 T 14-10-2018 IPR004872 Lipoprotein NlpA family LH59_01625 d2ada2a73cc3a4555656c4fefa4ef921 268 PIRSF PIRSF002854 1 268 2.5E-97 T 14-10-2018 IPR004872 Lipoprotein NlpA family LH59_01625 d2ada2a73cc3a4555656c4fefa4ef921 268 TIGRFAM TIGR00363 TIGR00363: lipoprotein, YaeC family 15 266 3.4E-71 T 14-10-2018 IPR004872 Lipoprotein NlpA family LH59_01625 d2ada2a73cc3a4555656c4fefa4ef921 268 SUPERFAMILY SSF53850 30 268 2.17E-78 T 14-10-2018 LH59_01625 d2ada2a73cc3a4555656c4fefa4ef921 268 Gene3D G3DSA:3.40.190.10 33 263 5.1E-91 T 14-10-2018 LH59_01625 d2ada2a73cc3a4555656c4fefa4ef921 268 Gene3D G3DSA:3.40.190.10 112 219 5.1E-91 T 14-10-2018 LH59_23100 35d94b60a57cc2a297cb1cd427430438 375 Pfam PF02653 Branched-chain amino acid transport system / permease component 56 351 4.0E-38 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_23100 35d94b60a57cc2a297cb1cd427430438 375 TIGRFAM TIGR03408 urea_trans_UrtC: urea ABC transporter, permease protein UrtC 48 362 1.3E-136 T 14-10-2018 IPR017778 ABC transporter, urea, permease protein, UrtC LH59_26890 3540d0f27f0f77c5d0e5549fecf6db9c 422 Gene3D G3DSA:3.30.300.30 327 420 9.5E-13 T 14-10-2018 LH59_26890 3540d0f27f0f77c5d0e5549fecf6db9c 422 Gene3D G3DSA:3.40.50.12780 2 326 2.1E-64 T 14-10-2018 LH59_26890 3540d0f27f0f77c5d0e5549fecf6db9c 422 Pfam PF00501 AMP-binding enzyme 138 287 5.3E-14 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 LH59_26890 3540d0f27f0f77c5d0e5549fecf6db9c 422 SUPERFAMILY SSF56801 122 390 1.44E-33 T 14-10-2018 LH59_22890 7c2e1fe2e613c4f4208692c7cc3f9a62 174 TIGRFAM TIGR02667 moaB_proteo: molybdenum cofactor biosynthesis protein B 7 166 7.2E-78 T 14-10-2018 IPR013484 Molybdenum cofactor biosynthesis protein B, proteobacteria GO:0006777 LH59_22890 7c2e1fe2e613c4f4208692c7cc3f9a62 174 Gene3D G3DSA:3.40.980.10 2 170 7.6E-50 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily LH59_22890 7c2e1fe2e613c4f4208692c7cc3f9a62 174 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 70 83 - T 14-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 LH59_22890 7c2e1fe2e613c4f4208692c7cc3f9a62 174 SUPERFAMILY SSF53218 9 166 2.22E-43 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily LH59_22890 7c2e1fe2e613c4f4208692c7cc3f9a62 174 PIRSF PIRSF006443 1 164 2.2E-61 T 14-10-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 LH59_22890 7c2e1fe2e613c4f4208692c7cc3f9a62 174 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 9 150 2.2E-37 T 14-10-2018 IPR001453 MoaB/Mog domain LH59_22890 7c2e1fe2e613c4f4208692c7cc3f9a62 174 SMART SM00852 12 156 2.6E-29 T 14-10-2018 IPR001453 MoaB/Mog domain LH59_22890 7c2e1fe2e613c4f4208692c7cc3f9a62 174 Pfam PF00994 Probable molybdopterin binding domain 12 153 4.4E-32 T 14-10-2018 IPR001453 MoaB/Mog domain LH59_16545 65260d45ecb5d1caeaa997d782c85991 322 SUPERFAMILY SSF53850 110 283 2.57E-15 T 14-10-2018 LH59_16545 65260d45ecb5d1caeaa997d782c85991 322 Gene3D G3DSA:3.40.190.10 126 248 1.8E-97 T 14-10-2018 LH59_16545 65260d45ecb5d1caeaa997d782c85991 322 Gene3D G3DSA:3.40.190.150 29 312 1.8E-97 T 14-10-2018 LH59_16545 65260d45ecb5d1caeaa997d782c85991 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 317 1.3E-78 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_16545 65260d45ecb5d1caeaa997d782c85991 322 PIRSF PIRSF017082 1 320 1.9E-72 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_06840 aed4ffda1ef81da061a40e0ef70b2bb1 302 Pfam PF09935 Protein of unknown function (DUF2167) 47 281 3.2E-80 T 14-10-2018 IPR018682 Protein of unknown function DUF2167, membrane LH59_24500 b52061d5446e608080a7dd0914bd563c 163 Pfam PF11158 Protein of unknown function (DUF2938) 10 158 8.3E-66 T 14-10-2018 IPR021329 Protein of unknown function DUF2938 LH59_04310 aed09a0373f4331bd44a392013a16edb 314 SUPERFAMILY SSF56300 3 157 9.74E-25 T 14-10-2018 LH59_04310 aed09a0373f4331bd44a392013a16edb 314 Pfam PF00149 Calcineurin-like phosphoesterase 4 91 1.3E-7 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 LH59_04310 aed09a0373f4331bd44a392013a16edb 314 Gene3D G3DSA:3.60.21.10 2 310 2.0E-35 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like LH59_00805 a64b5993d211b03543b113c3e583c77e 456 SUPERFAMILY SSF52540 3 167 4.28E-20 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_00805 a64b5993d211b03543b113c3e583c77e 456 Pfam PF11981 Domain of unknown function (DUF3482) 166 451 6.7E-99 T 14-10-2018 IPR021871 Protein of unknown function DUF3482 LH59_00805 a64b5993d211b03543b113c3e583c77e 456 Gene3D G3DSA:3.40.50.300 2 185 1.0E-27 T 14-10-2018 LH59_00805 a64b5993d211b03543b113c3e583c77e 456 Pfam PF01926 50S ribosome-binding GTPase 7 153 6.3E-17 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 LH59_08750 9af987d0f16162513f0842532eb59618 235 Pfam PF01522 Polysaccharide deacetylase 51 188 1.4E-33 T 14-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 LH59_08750 9af987d0f16162513f0842532eb59618 235 SUPERFAMILY SSF88713 15 209 1.24E-43 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 LH59_08750 9af987d0f16162513f0842532eb59618 235 Gene3D G3DSA:3.20.20.370 1 224 2.3E-59 T 14-10-2018 LH59_14105 de0b0a3603018f4c79845d5c50004904 409 SUPERFAMILY SSF103473 8 395 6.54E-56 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_14105 de0b0a3603018f4c79845d5c50004904 409 Pfam PF07690 Major Facilitator Superfamily 18 361 1.7E-38 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_14105 de0b0a3603018f4c79845d5c50004904 409 Gene3D G3DSA:1.20.1720.10 13 394 1.4E-88 T 14-10-2018 LH59_19655 39ab31e004c8e35b1970b1b9e91b4cbd 331 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 8 329 1.7E-140 T 14-10-2018 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 LH59_19655 39ab31e004c8e35b1970b1b9e91b4cbd 331 SUPERFAMILY SSF50129 13 144 9.91E-36 T 14-10-2018 IPR011032 GroES-like superfamily LH59_19655 39ab31e004c8e35b1970b1b9e91b4cbd 331 Pfam PF00107 Zinc-binding dehydrogenase 155 281 3.9E-32 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 LH59_19655 39ab31e004c8e35b1970b1b9e91b4cbd 331 SMART SM00829 14 327 3.4E-74 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 LH59_19655 39ab31e004c8e35b1970b1b9e91b4cbd 331 Gene3D G3DSA:3.90.180.10 19 327 1.0E-109 T 14-10-2018 LH59_19655 39ab31e004c8e35b1970b1b9e91b4cbd 331 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 33 107 1.1E-9 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 LH59_19655 39ab31e004c8e35b1970b1b9e91b4cbd 331 Gene3D G3DSA:3.40.50.720 124 266 1.0E-109 T 14-10-2018 LH59_19655 39ab31e004c8e35b1970b1b9e91b4cbd 331 SUPERFAMILY SSF51735 115 291 1.25E-50 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_12710 846c31caac93e2f97ecb5f73c03ad58d 454 Pfam PF03972 MmgE/PrpD family 11 443 1.5E-132 T 14-10-2018 IPR005656 MmgE/PrpD GO:0016829 LH59_12710 846c31caac93e2f97ecb5f73c03ad58d 454 Gene3D G3DSA:3.30.1330.120 272 403 1.1E-104 T 14-10-2018 LH59_12710 846c31caac93e2f97ecb5f73c03ad58d 454 SUPERFAMILY SSF103378 8 449 1.44E-120 T 14-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 LH59_12710 846c31caac93e2f97ecb5f73c03ad58d 454 Gene3D G3DSA:1.10.4100.10 28 418 1.1E-104 T 14-10-2018 LH59_10865 79d0808596009482e7a3091560208b2c 446 PIRSF PIRSF002808 1 437 1.9E-33 T 14-10-2018 IPR000849 Sugar phosphate transporter GO:0016021|GO:0022857|GO:0055085 LH59_10865 79d0808596009482e7a3091560208b2c 446 Gene3D G3DSA:1.20.1250.20 3 208 4.3E-40 T 14-10-2018 LH59_10865 79d0808596009482e7a3091560208b2c 446 Pfam PF07690 Major Facilitator Superfamily 19 311 6.2E-43 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_10865 79d0808596009482e7a3091560208b2c 446 Gene3D G3DSA:1.20.1250.20 235 431 2.5E-33 T 14-10-2018 LH59_10865 79d0808596009482e7a3091560208b2c 446 SUPERFAMILY SSF103473 6 431 2.22E-75 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_10650 0ee2b24633383053cf34be0d7ce4f67c 264 Gene3D G3DSA:3.90.1200.10 83 197 5.9E-7 T 14-10-2018 LH59_10650 0ee2b24633383053cf34be0d7ce4f67c 264 SUPERFAMILY SSF56112 28 245 6.27E-30 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily LH59_10650 0ee2b24633383053cf34be0d7ce4f67c 264 Pfam PF04655 Aminoglycoside/hydroxyurea antibiotic resistance kinase 3 245 2.9E-78 T 14-10-2018 IPR006748 Aminoglycoside/hydroxyurea antibiotic resistance kinase GO:0006468|GO:0016773|GO:0019748 LH59_05310 4decd7e04104fcc53e4c2c3aab4b9e2a 134 SUPERFAMILY SSF52833 9 128 3.04E-19 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_05310 4decd7e04104fcc53e4c2c3aab4b9e2a 134 Gene3D G3DSA:3.40.30.10 9 123 3.1E-8 T 14-10-2018 LH59_06600 62c73a13ce83c2eb2561fbd809c089de 236 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 25 228 4.6E-41 T 14-10-2018 IPR006214 Bax inhibitor 1-related LH59_07675 410f731558337b2af9eb461038ea6526 474 PIRSF PIRSF037227 2 474 4.4E-204 T 14-10-2018 IPR017145 Aminobenzoyl-glutamate utilization protein B LH59_07675 410f731558337b2af9eb461038ea6526 474 Pfam PF07687 Peptidase dimerisation domain 190 280 1.3E-4 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain LH59_07675 410f731558337b2af9eb461038ea6526 474 SUPERFAMILY SSF53187 7 439 4.44E-56 T 14-10-2018 LH59_07675 410f731558337b2af9eb461038ea6526 474 SUPERFAMILY SSF55031 191 294 5.58E-19 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain LH59_07675 410f731558337b2af9eb461038ea6526 474 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 20 424 9.4E-84 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 LH59_18845 fa6e2f81df4903f7a1bbbbf5e6b44fb1 253 PIRSF PIRSF006648 4 252 1.8E-28 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 LH59_18845 fa6e2f81df4903f7a1bbbbf5e6b44fb1 253 PRINTS PR00164 ABC-2 type transport system membrane protein signature 173 192 1.4E-12 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 LH59_18845 fa6e2f81df4903f7a1bbbbf5e6b44fb1 253 PRINTS PR00164 ABC-2 type transport system membrane protein signature 193 212 1.4E-12 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 LH59_18845 fa6e2f81df4903f7a1bbbbf5e6b44fb1 253 PRINTS PR00164 ABC-2 type transport system membrane protein signature 55 77 1.4E-12 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 LH59_18845 fa6e2f81df4903f7a1bbbbf5e6b44fb1 253 PRINTS PR00164 ABC-2 type transport system membrane protein signature 136 160 1.4E-12 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 LH59_18845 fa6e2f81df4903f7a1bbbbf5e6b44fb1 253 PRINTS PR00164 ABC-2 type transport system membrane protein signature 99 124 1.4E-12 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 LH59_18845 fa6e2f81df4903f7a1bbbbf5e6b44fb1 253 Pfam PF01061 ABC-2 type transporter 5 216 3.6E-35 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 LH59_03985 a1a69bbab4b923a5b0ad00145a6971e3 92 Pfam PF02201 SWIB/MDM2 domain 19 91 1.3E-29 T 14-10-2018 IPR003121 SWIB/MDM2 domain GO:0005515 LH59_03985 a1a69bbab4b923a5b0ad00145a6971e3 92 SMART SM00151 17 92 9.5E-35 T 14-10-2018 IPR019835 SWIB domain Reactome: R-HSA-3214858|Reactome: R-HSA-8939243 LH59_03985 a1a69bbab4b923a5b0ad00145a6971e3 92 Gene3D G3DSA:1.10.245.10 11 92 1.1E-28 T 14-10-2018 IPR036885 SWIB/MDM2 domain superfamily LH59_03985 a1a69bbab4b923a5b0ad00145a6971e3 92 SUPERFAMILY SSF47592 12 91 2.62E-28 T 14-10-2018 IPR036885 SWIB/MDM2 domain superfamily LH59_20075 3216fec408bee47e8446587e3a25c96c 182 Gene3D G3DSA:3.10.129.10 18 160 6.2E-26 T 14-10-2018 LH59_20075 3216fec408bee47e8446587e3a25c96c 182 Pfam PF14539 Domain of unknown function (DUF4442) 20 155 2.4E-16 T 14-10-2018 IPR027961 Protein of unknown function DUF4442 LH59_20075 3216fec408bee47e8446587e3a25c96c 182 SUPERFAMILY SSF54637 12 160 1.6E-20 T 14-10-2018 IPR029069 HotDog domain superfamily LH59_06320 5c8b4c37b6c4f8b3989f05c7df94c5ee 716 Pfam PF05506 Domain of unknown function (DUF756) 615 691 7.3E-13 T 14-10-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 LH59_06320 5c8b4c37b6c4f8b3989f05c7df94c5ee 716 Pfam PF05506 Domain of unknown function (DUF756) 515 601 4.4E-25 T 14-10-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 LH59_06320 5c8b4c37b6c4f8b3989f05c7df94c5ee 716 Gene3D G3DSA:3.40.720.10 36 216 8.2E-29 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 LH59_06320 5c8b4c37b6c4f8b3989f05c7df94c5ee 716 Gene3D G3DSA:3.40.720.10 292 490 5.4E-49 T 14-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 LH59_06320 5c8b4c37b6c4f8b3989f05c7df94c5ee 716 Pfam PF04185 Phosphoesterase family 46 445 2.1E-114 T 14-10-2018 IPR007312 Phosphoesterase GO:0016788 LH59_06320 5c8b4c37b6c4f8b3989f05c7df94c5ee 716 TIGRFAM TIGR03396 PC_PLC: phospholipase C, phosphocholine-specific 3 705 7.3E-275 T 14-10-2018 IPR017767 Bacterial phospholipase C, phosphocholine-specific GO:0034480 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 LH59_01370 c7625f1bb6b73a15b91897ddc5d83445 480 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 63 221 4.8E-20 T 14-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like LH59_09835 d796b8e10ecd7e4f8c1954e34ffb616f 339 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 160 324 6.4E-16 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_09835 d796b8e10ecd7e4f8c1954e34ffb616f 339 Gene3D G3DSA:1.10.3720.10 134 329 1.8E-22 T 14-10-2018 IPR035906 MetI-like superfamily LH59_09835 d796b8e10ecd7e4f8c1954e34ffb616f 339 SUPERFAMILY SSF161098 137 314 2.49E-24 T 14-10-2018 IPR035906 MetI-like superfamily LH59_25650 c7ca25cb7e8f7c4fcf5806ac5ee6e1ea 182 Gene3D G3DSA:2.60.120.480 5 167 9.7E-21 T 14-10-2018 IPR024060 Ureidoglycolate lyase domain superfamily GO:0004848 KEGG: 00230+4.3.2.3|MetaCyc: PWY-5694|MetaCyc: PWY-5705 LH59_25650 c7ca25cb7e8f7c4fcf5806ac5ee6e1ea 182 Pfam PF04115 Ureidoglycolate lyase 66 134 2.7E-13 T 14-10-2018 IPR007247 Ureidoglycolate lyase GO:0000256|GO:0050385 KEGG: 00230+4.3.2.3|MetaCyc: PWY-5694|MetaCyc: PWY-5705 LH59_25650 c7ca25cb7e8f7c4fcf5806ac5ee6e1ea 182 SUPERFAMILY SSF51182 7 159 2.42E-25 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_22290 58ce8a298bc3047ed1daebb7568f0fff 340 Gene3D G3DSA:3.40.190.10 122 228 5.1E-51 T 14-10-2018 LH59_22290 58ce8a298bc3047ed1daebb7568f0fff 340 Gene3D G3DSA:3.40.190.10 30 243 5.1E-51 T 14-10-2018 LH59_22290 58ce8a298bc3047ed1daebb7568f0fff 340 SMART SM00062 35 265 1.9E-46 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_22290 58ce8a298bc3047ed1daebb7568f0fff 340 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 38 255 2.0E-29 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_22290 58ce8a298bc3047ed1daebb7568f0fff 340 SUPERFAMILY SSF53850 26 260 6.26E-46 T 14-10-2018 LH59_06060 0d75fbd1dd997686c36e33e5d65d4605 500 Gene3D G3DSA:3.10.105.10 252 472 2.5E-121 T 14-10-2018 LH59_06060 0d75fbd1dd997686c36e33e5d65d4605 500 SUPERFAMILY SSF53850 21 497 1.39E-131 T 14-10-2018 LH59_06060 0d75fbd1dd997686c36e33e5d65d4605 500 Gene3D G3DSA:3.90.76.10 32 176 2.5E-121 T 14-10-2018 LH59_06060 0d75fbd1dd997686c36e33e5d65d4605 500 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 65 418 5.2E-86 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain LH59_06060 0d75fbd1dd997686c36e33e5d65d4605 500 PIRSF PIRSF002741 8 495 1.4E-104 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 LH59_06060 0d75fbd1dd997686c36e33e5d65d4605 500 Gene3D G3DSA:3.40.190.10 177 482 2.5E-121 T 14-10-2018 LH59_00865 78a8aab07f75b3fb9f2f95c06778b955 147 Pfam PF04386 Stringent starvation protein B 5 147 1.0E-32 T 14-10-2018 IPR007481 Stringent starvation protein B LH59_00865 78a8aab07f75b3fb9f2f95c06778b955 147 Gene3D G3DSA:2.30.30.220 1 126 1.2E-44 T 14-10-2018 IPR036760 SspB-like superfamily LH59_00865 78a8aab07f75b3fb9f2f95c06778b955 147 SUPERFAMILY SSF101738 3 110 1.83E-43 T 14-10-2018 IPR036760 SspB-like superfamily LH59_00865 78a8aab07f75b3fb9f2f95c06778b955 147 PIRSF PIRSF005276 1 147 1.7E-49 T 14-10-2018 IPR007481 Stringent starvation protein B LH59_02600 005145bdfa200d17841b7a68823b8384 275 SMART SM00530 25 97 5.8E-4 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LH59_02600 005145bdfa200d17841b7a68823b8384 275 Gene3D G3DSA:1.10.260.40 43 97 2.0E-6 T 14-10-2018 LH59_02600 005145bdfa200d17841b7a68823b8384 275 SUPERFAMILY SSF47413 45 93 1.45E-6 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 LH59_02600 005145bdfa200d17841b7a68823b8384 275 Gene3D G3DSA:3.30.450.180 120 269 1.3E-16 T 14-10-2018 LH59_02600 005145bdfa200d17841b7a68823b8384 275 Pfam PF13560 Helix-turn-helix domain 21 100 1.2E-16 T 14-10-2018 LH59_25900 56b5c34fe5813e8164824a5618446e51 393 SUPERFAMILY SSF103473 5 387 1.01E-33 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_25900 56b5c34fe5813e8164824a5618446e51 393 Pfam PF07690 Major Facilitator Superfamily 21 348 3.3E-16 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_25900 56b5c34fe5813e8164824a5618446e51 393 Gene3D G3DSA:1.20.1250.20 3 386 1.4E-30 T 14-10-2018 LH59_12505 7b648b561919bc2b842875027b16b508 427 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 7 417 4.4E-91 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit LH59_12505 7b648b561919bc2b842875027b16b508 427 PIRSF PIRSF006066 1 427 1.0E-93 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 LH59_12505 7b648b561919bc2b842875027b16b508 427 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 17 423 2.5E-95 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 LH59_15865 62a292688d60529f2cf8bf650f3da4a9 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 3.6E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_15865 62a292688d60529f2cf8bf650f3da4a9 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 3.6E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_15865 62a292688d60529f2cf8bf650f3da4a9 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 3.6E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_15865 62a292688d60529f2cf8bf650f3da4a9 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 187 0.0048 T 14-10-2018 LH59_15865 62a292688d60529f2cf8bf650f3da4a9 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 2.0E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_15865 62a292688d60529f2cf8bf650f3da4a9 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 2.0E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_15865 62a292688d60529f2cf8bf650f3da4a9 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 2.0E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_15865 62a292688d60529f2cf8bf650f3da4a9 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 2.0E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_15865 62a292688d60529f2cf8bf650f3da4a9 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 2.0E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_15865 62a292688d60529f2cf8bf650f3da4a9 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.0E-37 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_15865 62a292688d60529f2cf8bf650f3da4a9 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 244 3.3E-57 T 14-10-2018 LH59_15865 62a292688d60529f2cf8bf650f3da4a9 245 SUPERFAMILY SSF51735 4 245 2.01E-72 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_15865 62a292688d60529f2cf8bf650f3da4a9 245 Gene3D G3DSA:3.40.50.720 1 244 1.4E-76 T 14-10-2018 LH59_14840 391bd3525bb413038f9d773f79781545 337 Pfam PF03797 Autotransporter beta-domain 81 315 5.6E-18 T 14-10-2018 IPR005546 Autotransporter beta-domain LH59_14840 391bd3525bb413038f9d773f79781545 337 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 44 337 8.1E-27 T 14-10-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 LH59_14840 391bd3525bb413038f9d773f79781545 337 Gene3D G3DSA:2.40.128.130 26 337 3.1E-45 T 14-10-2018 IPR036709 Autotransporter beta-domain superfamily LH59_14840 391bd3525bb413038f9d773f79781545 337 SMART SM00869 75 326 5.8E-9 T 14-10-2018 IPR005546 Autotransporter beta-domain LH59_14840 391bd3525bb413038f9d773f79781545 337 SUPERFAMILY SSF103515 56 337 3.79E-26 T 14-10-2018 IPR036709 Autotransporter beta-domain superfamily LH59_12675 14974bdfbb9246d04d31c520e745f8e0 197 Gene3D G3DSA:3.90.1720.10 58 196 2.7E-44 T 14-10-2018 LH59_12675 14974bdfbb9246d04d31c520e745f8e0 197 SUPERFAMILY SSF54001 57 187 4.46E-41 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily LH59_12675 14974bdfbb9246d04d31c520e745f8e0 197 Pfam PF00877 NlpC/P60 family 75 183 2.4E-32 T 14-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain LH59_13405 2ea511d341b5dcd55ddfdb091c2bac52 195 SUPERFAMILY SSF143120 7 53 8.37E-6 T 14-10-2018 IPR036165 YefM-like superfamily LH59_13405 2ea511d341b5dcd55ddfdb091c2bac52 195 Pfam PF05598 Transposase domain (DUF772) 96 148 7.3E-10 T 14-10-2018 IPR008490 Transposase InsH, N-terminal LH59_22530 f7ca6f30aad1c7cd7b17129b42d33c65 316 PRINTS PR00625 DnaJ domain signature 61 80 1.7E-21 T 14-10-2018 IPR001623 DnaJ domain LH59_22530 f7ca6f30aad1c7cd7b17129b42d33c65 316 PRINTS PR00625 DnaJ domain signature 25 40 1.7E-21 T 14-10-2018 IPR001623 DnaJ domain LH59_22530 f7ca6f30aad1c7cd7b17129b42d33c65 316 PRINTS PR00625 DnaJ domain signature 41 61 1.7E-21 T 14-10-2018 IPR001623 DnaJ domain LH59_22530 f7ca6f30aad1c7cd7b17129b42d33c65 316 PRINTS PR00625 DnaJ domain signature 7 25 1.7E-21 T 14-10-2018 IPR001623 DnaJ domain LH59_22530 f7ca6f30aad1c7cd7b17129b42d33c65 316 Gene3D G3DSA:2.60.260.20 211 288 2.9E-24 T 14-10-2018 LH59_22530 f7ca6f30aad1c7cd7b17129b42d33c65 316 Gene3D G3DSA:2.60.260.20 129 210 3.3E-22 T 14-10-2018 LH59_22530 f7ca6f30aad1c7cd7b17129b42d33c65 316 Pfam PF01556 DnaJ C terminal domain 136 288 6.2E-31 T 14-10-2018 IPR002939 Chaperone DnaJ, C-terminal LH59_22530 f7ca6f30aad1c7cd7b17129b42d33c65 316 SUPERFAMILY SSF49493 127 225 2.62E-20 T 14-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 LH59_22530 f7ca6f30aad1c7cd7b17129b42d33c65 316 SUPERFAMILY SSF46565 1 86 8.64E-29 T 14-10-2018 IPR036869 Chaperone J-domain superfamily LH59_22530 f7ca6f30aad1c7cd7b17129b42d33c65 316 SUPERFAMILY SSF49493 217 299 2.88E-17 T 14-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 LH59_22530 f7ca6f30aad1c7cd7b17129b42d33c65 316 SMART SM00271 4 61 1.6E-26 T 14-10-2018 IPR001623 DnaJ domain LH59_22530 f7ca6f30aad1c7cd7b17129b42d33c65 316 Pfam PF00226 DnaJ domain 5 66 2.6E-23 T 14-10-2018 IPR001623 DnaJ domain LH59_22530 f7ca6f30aad1c7cd7b17129b42d33c65 316 Gene3D G3DSA:1.10.287.110 2 124 2.5E-32 T 14-10-2018 IPR036869 Chaperone J-domain superfamily LH59_23835 6178a4a0689704a11bd55b930c09ded8 349 SUPERFAMILY SSF51430 1 347 3.14E-108 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily LH59_23835 6178a4a0689704a11bd55b930c09ded8 349 Pfam PF00248 Aldo/keto reductase family 16 340 1.2E-71 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain LH59_23835 6178a4a0689704a11bd55b930c09ded8 349 Gene3D G3DSA:3.20.20.100 1 349 1.2E-131 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily LH59_27770 f1496ab717510d180f3fd5d23a4db093 121 SUPERFAMILY SSF53137 3 119 2.03E-49 T 14-10-2018 LH59_27770 f1496ab717510d180f3fd5d23a4db093 121 Gene3D G3DSA:3.30.420.100 1 121 1.7E-41 T 14-10-2018 LH59_27770 f1496ab717510d180f3fd5d23a4db093 121 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 2 121 26.054 T 14-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_27770 f1496ab717510d180f3fd5d23a4db093 121 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 1 121 2.6E-36 T 14-10-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_27770 f1496ab717510d180f3fd5d23a4db093 121 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 3 121 3.3E-35 T 14-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_11010 bdc88c16dbbca7b6364f9bdcc978adc1 679 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 376 674 2.2E-46 T 14-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 LH59_11010 bdc88c16dbbca7b6364f9bdcc978adc1 679 Gene3D G3DSA:3.30.1490.20 359 544 2.1E-37 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 LH59_11010 bdc88c16dbbca7b6364f9bdcc978adc1 679 Gene3D G3DSA:3.30.470.20 546 675 1.7E-22 T 14-10-2018 LH59_11010 bdc88c16dbbca7b6364f9bdcc978adc1 679 SUPERFAMILY SSF52009 236 322 5.76E-5 T 14-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 LH59_11010 bdc88c16dbbca7b6364f9bdcc978adc1 679 SUPERFAMILY SSF56059 363 674 1.88E-48 T 14-10-2018 LH59_13125 2411b8326ae96f1509a183c367ae08ed 227 Pfam PF10087 Uncharacterized protein conserved in bacteria (DUF2325) 129 209 1.2E-13 T 14-10-2018 IPR016772 Uncharacterised conserved protein UCP020408 LH59_21690 4d744a82e3c3040e8b04f40a33dc0d82 351 Gene3D G3DSA:3.40.190.10 37 313 5.7E-80 T 14-10-2018 LH59_21690 4d744a82e3c3040e8b04f40a33dc0d82 351 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 99 112 1.7E-6 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 LH59_21690 4d744a82e3c3040e8b04f40a33dc0d82 351 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 153 167 1.7E-6 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 LH59_21690 4d744a82e3c3040e8b04f40a33dc0d82 351 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 251 270 1.7E-6 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 LH59_21690 4d744a82e3c3040e8b04f40a33dc0d82 351 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 55 76 1.7E-6 T 14-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 LH59_21690 4d744a82e3c3040e8b04f40a33dc0d82 351 Gene3D G3DSA:3.40.190.10 138 329 5.7E-80 T 14-10-2018 LH59_21690 4d744a82e3c3040e8b04f40a33dc0d82 351 SUPERFAMILY SSF53850 30 347 1.86E-55 T 14-10-2018 LH59_21690 4d744a82e3c3040e8b04f40a33dc0d82 351 Pfam PF13416 Bacterial extracellular solute-binding protein 49 312 3.4E-27 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein LH59_14735 3d56eb6d791a2af9d8320f4237eb15eb 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 7.4E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_14735 3d56eb6d791a2af9d8320f4237eb15eb 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 7.4E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_14735 3d56eb6d791a2af9d8320f4237eb15eb 222 SUPERFAMILY SSF46689 13 83 5.49E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_14735 3d56eb6d791a2af9d8320f4237eb15eb 222 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 70 1.5E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_14735 3d56eb6d791a2af9d8320f4237eb15eb 222 Gene3D G3DSA:1.10.357.10 5 211 8.0E-55 T 14-10-2018 LH59_08645 d28e327bddf71ed29f4398081780ad07 269 SUPERFAMILY SSF161098 7 264 4.86E-54 T 14-10-2018 IPR035906 MetI-like superfamily LH59_08645 d28e327bddf71ed29f4398081780ad07 269 Gene3D G3DSA:1.10.3720.10 13 266 2.2E-46 T 14-10-2018 IPR035906 MetI-like superfamily LH59_08645 d28e327bddf71ed29f4398081780ad07 269 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 260 1.2E-15 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_27025 51b37e5a5d2b772411ff86df9f4c1dbc 476 Gene3D G3DSA:3.40.50.11290 215 312 2.5E-44 T 14-10-2018 LH59_27025 51b37e5a5d2b772411ff86df9f4c1dbc 476 Gene3D G3DSA:3.30.1490.270 349 409 2.5E-25 T 14-10-2018 LH59_27025 51b37e5a5d2b772411ff86df9f4c1dbc 476 PIRSF PIRSF005522 1 476 1.1E-228 T 14-10-2018 IPR016450 Uncharacterised conserved protein UCP005522 LH59_27025 51b37e5a5d2b772411ff86df9f4c1dbc 476 SUPERFAMILY SSF56059 20 467 4.22E-62 T 14-10-2018 LH59_27025 51b37e5a5d2b772411ff86df9f4c1dbc 476 Pfam PF14403 Circularly permuted ATP-grasp type 2 77 452 2.7E-165 T 14-10-2018 IPR025841 Circularly permuted ATP-grasp type 2 LH59_23965 4c59e4d5a118cf98217abe9053083197 149 Pfam PF13673 Acetyltransferase (GNAT) domain 56 136 7.4E-15 T 14-10-2018 IPR000182 GNAT domain LH59_23965 4c59e4d5a118cf98217abe9053083197 149 Gene3D G3DSA:3.40.630.30 1 146 5.6E-38 T 14-10-2018 LH59_23965 4c59e4d5a118cf98217abe9053083197 149 SUPERFAMILY SSF55729 1 142 9.76E-26 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_01740 cfe4d678c230dbe8c6c9683460c1f09e 477 Gene3D G3DSA:3.40.640.10 95 359 3.3E-154 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_01740 cfe4d678c230dbe8c6c9683460c1f09e 477 TIGRFAM TIGR00474 selA: L-seryl-tRNA(Sec) selenium transferase 9 465 4.3E-179 T 14-10-2018 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 LH59_01740 cfe4d678c230dbe8c6c9683460c1f09e 477 SUPERFAMILY SSF53383 75 375 1.46E-43 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_01740 cfe4d678c230dbe8c6c9683460c1f09e 477 Hamap MF_00423 L-seryl-tRNA(Sec) selenium transferase [selA]. 1 471 235.841 T 14-10-2018 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 LH59_01740 cfe4d678c230dbe8c6c9683460c1f09e 477 Gene3D G3DSA:3.90.1150.110 10 457 3.3E-154 T 14-10-2018 LH59_01740 cfe4d678c230dbe8c6c9683460c1f09e 477 Pfam PF12390 Selenocysteine synthase N terminal 9 46 3.8E-7 T 14-10-2018 IPR025862 L-seryl-tRNA selenium transferase N-terminal domain KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 LH59_01740 cfe4d678c230dbe8c6c9683460c1f09e 477 Pfam PF03841 L-seryl-tRNA selenium transferase 83 453 2.4E-161 T 14-10-2018 IPR018319 L-seryl-tRNA selenium transferase-like KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 LH59_13430 9ec8299130408ece904bde6e0c6eb169 105 Pfam PF07963 Prokaryotic N-terminal methylation motif 5 28 6.1E-9 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site LH59_13430 9ec8299130408ece904bde6e0c6eb169 105 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 7 27 - T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site LH59_13430 9ec8299130408ece904bde6e0c6eb169 105 SUPERFAMILY SSF54523 9 76 7.53E-8 T 14-10-2018 LH59_13430 9ec8299130408ece904bde6e0c6eb169 105 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 6 27 2.2E-7 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site LH59_04280 9b8fce7a44ab1cddd9aab40d72eae583 690 Pfam PF05170 AsmA family 1 575 3.1E-130 T 14-10-2018 IPR007844 AsmA LH59_20395 dfb13c95ff8ad456488d08b64a32192f 388 Pfam PF06250 Protein of unknown function (DUF1016) 25 369 7.7E-109 T 14-10-2018 IPR009362 Protein of unknown function DUF1016 LH59_08540 91fa2ce5852fd42af187ac8601ea2d5e 642 Pfam PF02705 K+ potassium transporter 30 562 5.4E-202 T 14-10-2018 IPR003855 Potassium transporter GO:0015079|GO:0016020|GO:0071805 LH59_08540 91fa2ce5852fd42af187ac8601ea2d5e 642 Hamap MF_01522 Low affinity potassium transport system protein kup [kup]. 21 642 33.127 T 14-10-2018 IPR023051 Potassium uptake protein, low affinity, Kup LH59_09950 2376886b79c0c1f83dacbff012116694 141 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 19 131 1.5E-15 T 14-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 LH59_09950 2376886b79c0c1f83dacbff012116694 141 Gene3D G3DSA:3.10.129.10 7 141 4.2E-48 T 14-10-2018 LH59_09950 2376886b79c0c1f83dacbff012116694 141 SUPERFAMILY SSF54637 11 137 9.0E-33 T 14-10-2018 IPR029069 HotDog domain superfamily LH59_09950 2376886b79c0c1f83dacbff012116694 141 Pfam PF03061 Thioesterase superfamily 50 125 1.9E-15 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 LH59_05840 0e7a00f31b3141433bef9a4ed73a1bf8 175 SUPERFAMILY SSF88946 11 102 1.45E-13 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 LH59_05840 0e7a00f31b3141433bef9a4ed73a1bf8 175 Pfam PF08281 Sigma-70, region 4 115 167 4.3E-14 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LH59_05840 0e7a00f31b3141433bef9a4ed73a1bf8 175 Gene3D G3DSA:1.10.1740.10 1 81 1.4E-10 T 14-10-2018 LH59_05840 0e7a00f31b3141433bef9a4ed73a1bf8 175 Pfam PF04542 Sigma-70 region 2 15 83 1.8E-12 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 LH59_05840 0e7a00f31b3141433bef9a4ed73a1bf8 175 Gene3D G3DSA:1.10.10.10 93 168 6.8E-11 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_05840 0e7a00f31b3141433bef9a4ed73a1bf8 175 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 12 168 3.3E-20 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 LH59_05840 0e7a00f31b3141433bef9a4ed73a1bf8 175 SUPERFAMILY SSF88659 109 167 5.01E-13 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like LH59_07830 b0dbff68468ce535d8f7fd8e62333d20 279 Pfam PF01163 RIO1 family 86 177 7.3E-6 T 14-10-2018 LH59_07830 b0dbff68468ce535d8f7fd8e62333d20 279 SUPERFAMILY SSF56112 47 239 1.81E-13 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily LH59_17510 08cebc4d2d66051df5d64403a49f9263 499 TIGRFAM TIGR01539 portal_lambda: phage portal protein, lambda family 30 482 1.8E-88 T 14-10-2018 IPR006429 Phage portal protein, lambda family GO:0005198|GO:0019068 LH59_17510 08cebc4d2d66051df5d64403a49f9263 499 Pfam PF05136 Phage portal protein, lambda family 32 376 6.3E-104 T 14-10-2018 IPR006429 Phage portal protein, lambda family GO:0005198|GO:0019068 LH59_25425 9a8f833f4e38c0b0edfce02474f987af 640 Pfam PF00664 ABC transporter transmembrane region 35 290 5.8E-8 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 LH59_25425 9a8f833f4e38c0b0edfce02474f987af 640 Gene3D G3DSA:3.40.50.300 331 579 8.3E-68 T 14-10-2018 LH59_25425 9a8f833f4e38c0b0edfce02474f987af 640 Pfam PF00005 ABC transporter 357 509 1.1E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_25425 9a8f833f4e38c0b0edfce02474f987af 640 SUPERFAMILY SSF90123 20 326 1.44E-41 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 LH59_25425 9a8f833f4e38c0b0edfce02474f987af 640 SMART SM00382 365 556 2.2E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_25425 9a8f833f4e38c0b0edfce02474f987af 640 TIGRFAM TIGR01842 type_I_sec_PrtD: type I secretion system ATPase 23 568 1.6E-222 T 14-10-2018 IPR010128 ATPase, type I secretion system, PrtD GO:0005524|GO:0008565|GO:0016021|GO:0030253|GO:0030256 LH59_25425 9a8f833f4e38c0b0edfce02474f987af 640 Gene3D G3DSA:1.20.1560.10 17 324 8.3E-32 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 LH59_25425 9a8f833f4e38c0b0edfce02474f987af 640 ProSitePatterns PS00211 ABC transporters family signature. 482 496 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_25425 9a8f833f4e38c0b0edfce02474f987af 640 SUPERFAMILY SSF52540 331 569 7.78E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_25445 0f9e5db8b81ee434f11c772570b14547 451 Pfam PF07804 HipA-like C-terminal domain 160 416 8.0E-47 T 14-10-2018 IPR012893 HipA-like, C-terminal LH59_25445 0f9e5db8b81ee434f11c772570b14547 451 Pfam PF13657 HipA N-terminal domain 10 111 1.8E-19 T 14-10-2018 IPR017508 HipA, N-terminal subdomain 1 LH59_25445 0f9e5db8b81ee434f11c772570b14547 451 TIGRFAM TIGR03071 couple_hipA: HipA N-terminal domain 10 111 4.1E-25 T 14-10-2018 IPR017508 HipA, N-terminal subdomain 1 LH59_19130 60fa9fb5f5e3026b9f1788dfbb499171 291 Pfam PF13557 Putative MetA-pathway of phenol degradation 52 287 2.0E-58 T 14-10-2018 IPR025737 MetA-pathway of phenol degradation, putative LH59_20335 efb2106402501fce32ec93946fcff436 169 SUPERFAMILY SSF50891 2 168 3.8E-58 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily LH59_20335 efb2106402501fce32ec93946fcff436 169 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 20 35 6.7E-12 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 LH59_20335 efb2106402501fce32ec93946fcff436 169 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 46 58 6.7E-12 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 LH59_20335 efb2106402501fce32ec93946fcff436 169 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 123 138 6.7E-12 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 LH59_20335 efb2106402501fce32ec93946fcff436 169 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 41 58 - T 14-10-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 LH59_20335 efb2106402501fce32ec93946fcff436 169 PIRSF PIRSF001467 1 169 4.3E-26 T 14-10-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 LH59_20335 efb2106402501fce32ec93946fcff436 169 Gene3D G3DSA:2.40.100.10 3 168 8.4E-70 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily LH59_20335 efb2106402501fce32ec93946fcff436 169 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 7 166 1.5E-46 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 LH59_01165 cfc3e684c13447801e2081fa3a684fff 344 Pfam PF02628 Cytochrome oxidase assembly protein 10 320 2.9E-80 T 14-10-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 LH59_26695 78a81936c9108635a820703f965f192e 197 Gene3D G3DSA:3.40.50.10490 1 196 4.4E-72 T 14-10-2018 LH59_26695 78a81936c9108635a820703f965f192e 197 SUPERFAMILY SSF53697 2 191 5.26E-55 T 14-10-2018 LH59_26695 78a81936c9108635a820703f965f192e 197 Hamap MF_00067 Phosphoheptose isomerase [gmhA]. 3 192 35.997 T 14-10-2018 IPR004515 Phosphoheptose isomerase GO:0005737|GO:0008968 KEGG: 00540+5.3.1.28|MetaCyc: PWY-6478 LH59_26695 78a81936c9108635a820703f965f192e 197 Pfam PF13580 SIS domain 11 146 3.1E-33 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 LH59_16945 1f1af59af6d7a6d4476dabc4571c990c 112 SUPERFAMILY SSF54292 5 108 2.06E-28 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 LH59_16945 1f1af59af6d7a6d4476dabc4571c990c 112 ProSitePatterns PS00814 Adrenodoxin family, iron-sulfur binding region signature. 42 52 - T 14-10-2018 IPR018298 Adrenodoxin, iron-sulphur binding site GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 LH59_16945 1f1af59af6d7a6d4476dabc4571c990c 112 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 14 91 1.9E-11 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 LH59_16945 1f1af59af6d7a6d4476dabc4571c990c 112 TIGRFAM TIGR02007 fdx_isc: ferredoxin, 2Fe-2S type, ISC system 2 111 2.0E-55 T 14-10-2018 IPR011536 Ferredoxin 2Fe-2S type, proteobacteria GO:0009055|GO:0051537 LH59_16945 1f1af59af6d7a6d4476dabc4571c990c 112 PRINTS PR00355 Adrenodoxin signature 42 52 1.3E-7 T 14-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 LH59_16945 1f1af59af6d7a6d4476dabc4571c990c 112 PRINTS PR00355 Adrenodoxin signature 83 91 1.3E-7 T 14-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 LH59_16945 1f1af59af6d7a6d4476dabc4571c990c 112 PRINTS PR00355 Adrenodoxin signature 60 74 1.3E-7 T 14-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 LH59_16945 1f1af59af6d7a6d4476dabc4571c990c 112 Gene3D G3DSA:3.10.20.30 1 112 2.7E-32 T 14-10-2018 IPR012675 Beta-grasp domain superfamily LH59_27555 720b9159435f5f42411710c567831ac5 136 Pfam PF06476 Protein of unknown function (DUF1090) 25 127 2.0E-33 T 14-10-2018 IPR009468 Protein of unknown function DUF1090 LH59_01800 2f5aad2de17a53274de9070391ffe339 125 PIRSF PIRSF009151 3 124 4.6E-58 T 14-10-2018 IPR008497 Protein of unknown function DUF779 LH59_01800 2f5aad2de17a53274de9070391ffe339 125 Pfam PF05610 Protein of unknown function (DUF779) 17 110 3.1E-48 T 14-10-2018 IPR008497 Protein of unknown function DUF779 LH59_00090 d6342bfc2a91ffddc3ce3016d9745943 94 ProSitePatterns PS00151 Acylphosphatase signature 2. 37 53 - T 14-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 LH59_00090 d6342bfc2a91ffddc3ce3016d9745943 94 Pfam PF00708 Acylphosphatase 9 92 1.2E-23 T 14-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 LH59_00090 d6342bfc2a91ffddc3ce3016d9745943 94 PRINTS PR00112 Acylphosphatase signature 8 23 2.8E-6 T 14-10-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 LH59_00090 d6342bfc2a91ffddc3ce3016d9745943 94 PRINTS PR00112 Acylphosphatase signature 29 54 2.8E-6 T 14-10-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 LH59_00090 d6342bfc2a91ffddc3ce3016d9745943 94 SUPERFAMILY SSF54975 4 92 2.83E-25 T 14-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 LH59_00090 d6342bfc2a91ffddc3ce3016d9745943 94 Gene3D G3DSA:3.30.70.100 1 93 1.3E-27 T 14-10-2018 LH59_21015 f4fde2e603c3f174c3c0400050f42b25 430 Gene3D G3DSA:3.50.50.60 31 382 4.1E-68 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_21015 f4fde2e603c3f174c3c0400050f42b25 430 Gene3D G3DSA:3.30.9.10 124 344 4.1E-68 T 14-10-2018 LH59_21015 f4fde2e603c3f174c3c0400050f42b25 430 SUPERFAMILY SSF51905 30 401 7.12E-42 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_21015 f4fde2e603c3f174c3c0400050f42b25 430 Pfam PF01266 FAD dependent oxidoreductase 31 381 7.8E-54 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 LH59_03115 fc8a12a6bb54856c4453044fdae53d63 287 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 7 282 31.135 T 14-10-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 LH59_03115 fc8a12a6bb54856c4453044fdae53d63 287 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 10 283 1.6E-70 T 14-10-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 LH59_03115 fc8a12a6bb54856c4453044fdae53d63 287 SUPERFAMILY SSF51735 108 282 4.47E-40 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_03115 fc8a12a6bb54856c4453044fdae53d63 287 SUPERFAMILY SSF53223 8 107 1.04E-28 T 14-10-2018 LH59_03115 fc8a12a6bb54856c4453044fdae53d63 287 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 12 95 6.0E-21 T 14-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 LH59_03115 fc8a12a6bb54856c4453044fdae53d63 287 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 122 172 1.4E-9 T 14-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase LH59_03115 fc8a12a6bb54856c4453044fdae53d63 287 Gene3D G3DSA:3.40.50.10860 10 267 9.1E-75 T 14-10-2018 LH59_03115 fc8a12a6bb54856c4453044fdae53d63 287 Gene3D G3DSA:3.40.50.720 121 248 9.1E-75 T 14-10-2018 LH59_06460 2a8a451266e43f606abd619e72b9dc06 217 Pfam PF01794 Ferric reductase like transmembrane component 64 177 1.2E-15 T 14-10-2018 IPR013130 Ferric reductase transmembrane component-like domain LH59_06460 2a8a451266e43f606abd619e72b9dc06 217 Hamap MF_01207 Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ [msrQ]. 22 216 20.333 T 14-10-2018 IPR022837 Protein-methionine-sulfoxide reductase subunit MsrQ GO:0005887|GO:0030091 LH59_15085 cf6d10742449e32d329f89f8b19e3f50 497 PIRSF PIRSF012702 1 495 8.6E-162 T 14-10-2018 IPR009197 Microcystin LR degradation protein MlrC LH59_15085 cf6d10742449e32d329f89f8b19e3f50 497 Pfam PF07171 MlrC C-terminus 298 479 7.5E-53 T 14-10-2018 IPR010799 Microcystin LR degradation protein MlrC, C-terminal LH59_15085 cf6d10742449e32d329f89f8b19e3f50 497 Pfam PF07364 Metallopeptidase family M81 2 285 8.8E-92 T 14-10-2018 IPR015995 Microcystin LR degradation protein MlrC, N-terminal LH59_07845 694b4b39bf3c3f278003503c6b2b14d3 316 Gene3D G3DSA:3.40.718.10 1 316 4.9E-131 T 14-10-2018 LH59_07845 694b4b39bf3c3f278003503c6b2b14d3 316 SUPERFAMILY SSF53659 1 315 3.27E-109 T 14-10-2018 LH59_07845 694b4b39bf3c3f278003503c6b2b14d3 316 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 24 311 5.7E-111 T 14-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 LH59_07845 694b4b39bf3c3f278003503c6b2b14d3 316 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 1 314 3.0E-117 T 14-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 LH59_28250 4f48a5d0b7a2592a985ce4952c216483 123 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 44 97 3.0E-7 T 14-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 LH59_28250 4f48a5d0b7a2592a985ce4952c216483 123 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 10 108 1.7E-11 T 14-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 LH59_28250 4f48a5d0b7a2592a985ce4952c216483 123 Gene3D G3DSA:3.30.230.10 1 122 2.7E-24 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup LH59_28250 4f48a5d0b7a2592a985ce4952c216483 123 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 61 75 - T 14-10-2018 IPR020539 Ribonuclease P, conserved site GO:0004526 LH59_28250 4f48a5d0b7a2592a985ce4952c216483 123 Pfam PF00825 Ribonuclease P 6 111 3.6E-20 T 14-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 LH59_28250 4f48a5d0b7a2592a985ce4952c216483 123 SUPERFAMILY SSF54211 5 108 6.57E-19 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold LH59_28250 4f48a5d0b7a2592a985ce4952c216483 123 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 6 120 13.914 T 14-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 LH59_16265 2a6c00c6954cfe07bb92a4e4726c361f 348 Pfam PF02615 Malate/L-lactate dehydrogenase 13 341 7.0E-110 T 14-10-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0016491|GO:0055114 LH59_16265 2a6c00c6954cfe07bb92a4e4726c361f 348 Gene3D G3DSA:1.10.1530.10 20 344 9.4E-105 T 14-10-2018 LH59_16265 2a6c00c6954cfe07bb92a4e4726c361f 348 Gene3D G3DSA:3.30.1370.60 75 324 9.4E-105 T 14-10-2018 LH59_16265 2a6c00c6954cfe07bb92a4e4726c361f 348 SUPERFAMILY SSF89733 10 345 1.57E-104 T 14-10-2018 IPR036111 Malate/L-sulfolactate/L-lactate dehydrogenase-like superfamily GO:0016491|GO:0055114 LH59_04525 602a24f2f2c9abba2e4af7c931a76bb6 266 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 265 5.8E-64 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 LH59_04525 602a24f2f2c9abba2e4af7c931a76bb6 266 SUPERFAMILY SSF52096 4 266 2.2E-80 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily LH59_04525 602a24f2f2c9abba2e4af7c931a76bb6 266 TIGRFAM TIGR02280 PaaB1: phenylacetate degradation probable enoyl-CoA hydratase PaaB 10 266 5.5E-106 T 14-10-2018 IPR011968 Phenylacetate degradation probable enoyl-CoA hydratase PaaB GO:0010124 KEGG: 00360+5.3.3.18 LH59_04525 602a24f2f2c9abba2e4af7c931a76bb6 266 Gene3D G3DSA:1.10.12.10 209 266 1.4E-20 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal LH59_04525 602a24f2f2c9abba2e4af7c931a76bb6 266 Gene3D G3DSA:3.90.226.10 2 207 7.7E-68 T 14-10-2018 LH59_13475 0ef0bf934f7fae7341bf971a682892c9 154 Gene3D G3DSA:1.10.1660.10 4 137 1.8E-33 T 14-10-2018 LH59_13475 0ef0bf934f7fae7341bf971a682892c9 154 SUPERFAMILY SSF46955 13 136 4.03E-29 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily LH59_13475 0ef0bf934f7fae7341bf971a682892c9 154 TIGRFAM TIGR01950 SoxR: redox-sensitive transcriptional activator SoxR 13 152 1.6E-62 T 14-10-2018 IPR010211 Redox-sensitive transcriptional activator SoxR GO:0003677|GO:0006355|GO:0006979|GO:0051537 LH59_13475 0ef0bf934f7fae7341bf971a682892c9 154 Pfam PF09278 MerR, DNA binding 56 121 1.6E-17 T 14-10-2018 IPR015358 Transcription regulator MerR, DNA binding LH59_13475 0ef0bf934f7fae7341bf971a682892c9 154 SMART SM00422 13 81 2.1E-23 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LH59_13475 0ef0bf934f7fae7341bf971a682892c9 154 Pfam PF00376 MerR family regulatory protein 14 50 2.9E-14 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LH59_13475 0ef0bf934f7fae7341bf971a682892c9 154 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 48 68 2.3E-10 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LH59_13475 0ef0bf934f7fae7341bf971a682892c9 154 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 25 38 2.3E-10 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LH59_13475 0ef0bf934f7fae7341bf971a682892c9 154 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 14 25 2.3E-10 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LH59_15745 cfb8effc278e68a31bffaa45d0ff0ce0 142 Gene3D G3DSA:1.10.10.10 1 45 1.3E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_15745 cfb8effc278e68a31bffaa45d0ff0ce0 142 Gene3D G3DSA:3.30.70.920 46 129 1.1E-27 T 14-10-2018 LH59_15745 cfb8effc278e68a31bffaa45d0ff0ce0 142 SUPERFAMILY SSF46785 2 83 2.26E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_15745 cfb8effc278e68a31bffaa45d0ff0ce0 142 Pfam PF01037 Lrp/AsnC ligand binding domain 59 132 2.6E-23 T 14-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain LH59_15745 cfb8effc278e68a31bffaa45d0ff0ce0 142 Pfam PF13412 Winged helix-turn-helix DNA-binding 2 40 7.6E-16 T 14-10-2018 LH59_15745 cfb8effc278e68a31bffaa45d0ff0ce0 142 SMART SM00344 2 102 1.7E-39 T 14-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 LH59_15745 cfb8effc278e68a31bffaa45d0ff0ce0 142 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 9 20 8.3E-9 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_15745 cfb8effc278e68a31bffaa45d0ff0ce0 142 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 39 8.3E-9 T 14-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 LH59_15745 cfb8effc278e68a31bffaa45d0ff0ce0 142 SUPERFAMILY SSF54909 54 140 2.55E-22 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel LH59_25665 fe137a37797a13620830d8ea2c02f607 397 SUPERFAMILY SSF103473 2 383 4.71E-54 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_25665 fe137a37797a13620830d8ea2c02f607 397 Gene3D G3DSA:1.20.1250.20 2 386 9.0E-44 T 14-10-2018 LH59_25665 fe137a37797a13620830d8ea2c02f607 397 Pfam PF07690 Major Facilitator Superfamily 24 347 9.2E-30 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_09315 b06ba883880a4e2a8625f62cfa623955 322 Pfam PF01636 Phosphotransferase enzyme family 27 262 2.3E-32 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase LH59_09315 b06ba883880a4e2a8625f62cfa623955 322 SUPERFAMILY SSF56112 5 314 3.06E-71 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily LH59_09315 b06ba883880a4e2a8625f62cfa623955 322 Gene3D G3DSA:3.30.200.20 1 102 2.5E-35 T 14-10-2018 LH59_09315 b06ba883880a4e2a8625f62cfa623955 322 Gene3D G3DSA:3.90.1200.10 106 316 3.5E-68 T 14-10-2018 LH59_09315 b06ba883880a4e2a8625f62cfa623955 322 Hamap MF_00301 Homoserine kinase [thrB]. 1 322 156.977 T 14-10-2018 IPR005280 Homoserine kinase, type II GO:0004413|GO:0009088 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 LH59_09315 b06ba883880a4e2a8625f62cfa623955 322 TIGRFAM TIGR00938 thrB_alt: homoserine kinase 1 311 1.6E-95 T 14-10-2018 IPR005280 Homoserine kinase, type II GO:0004413|GO:0009088 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 LH59_13040 7c6a2d7b64f9024de5beecde5912f9bc 403 Gene3D G3DSA:1.20.1250.20 17 388 1.4E-44 T 14-10-2018 LH59_13040 7c6a2d7b64f9024de5beecde5912f9bc 403 Pfam PF07690 Major Facilitator Superfamily 25 238 4.4E-21 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_13040 7c6a2d7b64f9024de5beecde5912f9bc 403 SUPERFAMILY SSF103473 8 396 2.35E-53 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_25460 04840a691c6ca43a6a101c5b3ba80305 168 Pfam PF04542 Sigma-70 region 2 10 74 2.3E-8 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 LH59_25460 04840a691c6ca43a6a101c5b3ba80305 168 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 8 164 1.0E-19 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 LH59_25460 04840a691c6ca43a6a101c5b3ba80305 168 SUPERFAMILY SSF88946 7 89 7.46E-12 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 LH59_25460 04840a691c6ca43a6a101c5b3ba80305 168 Gene3D G3DSA:1.10.1740.10 3 70 1.5E-8 T 14-10-2018 LH59_25460 04840a691c6ca43a6a101c5b3ba80305 168 Pfam PF08281 Sigma-70, region 4 109 157 9.6E-16 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LH59_25460 04840a691c6ca43a6a101c5b3ba80305 168 Gene3D G3DSA:1.10.10.10 71 167 1.1E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_25460 04840a691c6ca43a6a101c5b3ba80305 168 SUPERFAMILY SSF88659 103 165 8.07E-14 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like LH59_09290 5664ec8d11c578a8d8c3b16d313ebbcf 453 Pfam PF13629 Pilus formation protein N terminal region 25 91 2.8E-14 T 14-10-2018 IPR032789 Pilus formation protein, N-terminal LH59_09290 5664ec8d11c578a8d8c3b16d313ebbcf 453 Pfam PF00263 Bacterial type II and III secretion system protein 236 392 6.3E-42 T 14-10-2018 IPR004846 Type II/III secretion system GO:0009306 LH59_09290 5664ec8d11c578a8d8c3b16d313ebbcf 453 PRINTS PR01337 Type III secretion system outer membrane G protein family signature 371 390 2.4E-7 T 14-10-2018 IPR003522 Type III secretion system outer membrane pore YscC/HrcC GO:0009306 LH59_09290 5664ec8d11c578a8d8c3b16d313ebbcf 453 PRINTS PR01337 Type III secretion system outer membrane G protein family signature 284 299 2.4E-7 T 14-10-2018 IPR003522 Type III secretion system outer membrane pore YscC/HrcC GO:0009306 LH59_09290 5664ec8d11c578a8d8c3b16d313ebbcf 453 PRINTS PR01337 Type III secretion system outer membrane G protein family signature 81 98 2.4E-7 T 14-10-2018 IPR003522 Type III secretion system outer membrane pore YscC/HrcC GO:0009306 LH59_09290 5664ec8d11c578a8d8c3b16d313ebbcf 453 PRINTS PR01337 Type III secretion system outer membrane G protein family signature 161 181 2.4E-7 T 14-10-2018 IPR003522 Type III secretion system outer membrane pore YscC/HrcC GO:0009306 LH59_17525 178c3e10465406d86195c70b2f55b2c9 165 Pfam PF07471 Phage DNA packaging protein Nu1 70 150 2.0E-14 T 14-10-2018 IPR010906 Bacteriophage lambda, Nu1, terminase small subunit LH59_25475 23c6bf1dc9cb4415f833aac90c3d9b32 217 Pfam PF01081 KDPG and KHG aldolase 10 189 8.6E-30 T 14-10-2018 IPR000887 KDPG/KHG aldolase GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 LH59_25475 23c6bf1dc9cb4415f833aac90c3d9b32 217 Gene3D G3DSA:3.20.20.70 8 215 3.7E-65 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_25475 23c6bf1dc9cb4415f833aac90c3d9b32 217 SUPERFAMILY SSF51569 4 207 3.3E-58 T 14-10-2018 LH59_19555 34838f527f1613bc8895136c831096b4 108 SMART SM00858 18 89 6.3E-11 T 14-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 LH59_19555 34838f527f1613bc8895136c831096b4 108 Gene3D G3DSA:3.90.1210.30 10 92 6.2E-22 T 14-10-2018 LH59_19555 34838f527f1613bc8895136c831096b4 108 Pfam PF08666 SAF domain 18 88 3.7E-9 T 14-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 LH59_23675 d0e1dde2e3612555cb36c1fcfb3c9478 168 SUPERFAMILY SSF88659 81 165 5.67E-16 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like LH59_23675 d0e1dde2e3612555cb36c1fcfb3c9478 168 SUPERFAMILY SSF88946 11 93 1.14E-7 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 LH59_23675 d0e1dde2e3612555cb36c1fcfb3c9478 168 Pfam PF04542 Sigma-70 region 2 13 75 2.4E-4 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 LH59_23675 d0e1dde2e3612555cb36c1fcfb3c9478 168 Gene3D G3DSA:1.10.10.10 82 166 6.9E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_23675 d0e1dde2e3612555cb36c1fcfb3c9478 168 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 13 162 3.3E-20 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 LH59_23675 d0e1dde2e3612555cb36c1fcfb3c9478 168 Pfam PF08281 Sigma-70, region 4 106 157 4.9E-14 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LH59_13105 6c9ac4d2fa78bc87677ed87cb72939da 541 Pfam PF13598 Domain of unknown function (DUF4139) 210 533 1.5E-64 T 14-10-2018 IPR037291 Domain of unknown function DUF4139 LH59_13105 6c9ac4d2fa78bc87677ed87cb72939da 541 TIGRFAM TIGR02231 TIGR02231: conserved hypothetical protein 19 538 7.9E-148 T 14-10-2018 IPR011935 Conserved hypothetical protein CHP02231 LH59_13105 6c9ac4d2fa78bc87677ed87cb72939da 541 Pfam PF13600 N-terminal domain of unknown function (DUF4140) 22 120 6.0E-24 T 14-10-2018 IPR025554 Domain of unknown function DUF4140 LH59_14120 025dcbbbe8875a1ba1c77c40810f431c 321 Pfam PF01032 FecCD transport family 9 315 4.2E-82 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 LH59_14120 025dcbbbe8875a1ba1c77c40810f431c 321 SUPERFAMILY SSF81345 2 315 1.23E-71 T 14-10-2018 IPR037294 ABC transporter, BtuC-like LH59_14120 025dcbbbe8875a1ba1c77c40810f431c 321 Gene3D G3DSA:1.10.3470.10 1 320 3.3E-84 T 14-10-2018 IPR037294 ABC transporter, BtuC-like LH59_00915 272647af82594aa161a30c309eba147e 178 TIGRFAM TIGR01410 tatB: twin arginine-targeting protein translocase TatB 2 79 1.1E-20 T 14-10-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 LH59_00915 272647af82594aa161a30c309eba147e 178 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 21 40 1.9E-15 T 14-10-2018 LH59_00915 272647af82594aa161a30c309eba147e 178 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 40 58 1.9E-15 T 14-10-2018 LH59_00915 272647af82594aa161a30c309eba147e 178 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 1 21 1.9E-15 T 14-10-2018 LH59_00915 272647af82594aa161a30c309eba147e 178 Pfam PF02416 mttA/Hcf106 family 4 51 4.4E-9 T 14-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 LH59_00915 272647af82594aa161a30c309eba147e 178 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 1 174 17.263 T 14-10-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 LH59_01545 d1a57fd245fe88d5bcf09a760cbfe781 116 SUPERFAMILY SSF54292 4 95 1.84E-20 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 LH59_01545 d1a57fd245fe88d5bcf09a760cbfe781 116 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 40 48 - T 14-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 LH59_01545 d1a57fd245fe88d5bcf09a760cbfe781 116 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 16 87 1.3E-11 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 LH59_01545 d1a57fd245fe88d5bcf09a760cbfe781 116 Gene3D G3DSA:3.10.20.30 2 96 1.3E-20 T 14-10-2018 IPR012675 Beta-grasp domain superfamily LH59_27820 fc4c8bb01d23c28fb866f5ee3b005392 393 Gene3D G3DSA:3.40.640.10 5 256 2.5E-84 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_27820 fc4c8bb01d23c28fb866f5ee3b005392 393 PIRSF PIRSF001434 2 393 1.2E-132 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 LH59_27820 fc4c8bb01d23c28fb866f5ee3b005392 393 SUPERFAMILY SSF53383 26 390 4.71E-107 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_27820 fc4c8bb01d23c28fb866f5ee3b005392 393 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 200 214 - T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 LH59_27820 fc4c8bb01d23c28fb866f5ee3b005392 393 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 12 389 1.9E-119 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 LH59_27820 fc4c8bb01d23c28fb866f5ee3b005392 393 Gene3D G3DSA:3.90.1150.10 258 393 3.0E-44 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_14935 5ec1b264db14727ab5c3645bec162689 70 Pfam PF07869 Protein of unknown function (DUF1656) 4 58 1.8E-22 T 14-10-2018 IPR012451 Protein of unknown function DUF1656 LH59_19115 fa97acc5073d81fe0dea8a54a399ceb4 375 SUPERFAMILY SSF46894 294 362 4.08E-8 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LH59_19115 fa97acc5073d81fe0dea8a54a399ceb4 375 SMART SM00421 305 362 2.4E-4 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 LH59_19115 fa97acc5073d81fe0dea8a54a399ceb4 375 Gene3D G3DSA:1.10.10.10 301 364 1.7E-6 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_25705 91e4ba9e84d91fd77afb5c76743422a5 298 SUPERFAMILY SSF103481 51 143 1.01E-12 T 14-10-2018 LH59_25705 91e4ba9e84d91fd77afb5c76743422a5 298 Pfam PF00892 EamA-like transporter family 158 289 5.8E-16 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_25705 91e4ba9e84d91fd77afb5c76743422a5 298 Pfam PF00892 EamA-like transporter family 11 143 1.1E-20 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_25705 91e4ba9e84d91fd77afb5c76743422a5 298 SUPERFAMILY SSF103481 191 295 4.45E-9 T 14-10-2018 LH59_07195 ba8cf14ef2e63d7271a962351e43fa76 79 Pfam PF00550 Phosphopantetheine attachment site 20 73 7.6E-9 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain LH59_07195 ba8cf14ef2e63d7271a962351e43fa76 79 Gene3D G3DSA:1.10.1200.10 4 78 7.1E-16 T 14-10-2018 IPR036736 ACP-like superfamily LH59_07195 ba8cf14ef2e63d7271a962351e43fa76 79 SUPERFAMILY SSF47336 1 76 7.85E-12 T 14-10-2018 IPR036736 ACP-like superfamily LH59_22770 eff2bbd8a1acb5c7dcb15c708cd1a3b3 225 SMART SM00014 90 203 3.6E-10 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase LH59_22770 eff2bbd8a1acb5c7dcb15c708cd1a3b3 225 Pfam PF01569 PAP2 superfamily 91 202 1.7E-19 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase LH59_22770 eff2bbd8a1acb5c7dcb15c708cd1a3b3 225 Gene3D G3DSA:1.20.144.10 127 220 2.9E-14 T 14-10-2018 LH59_22770 eff2bbd8a1acb5c7dcb15c708cd1a3b3 225 SUPERFAMILY SSF48317 6 208 4.36E-31 T 14-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily LH59_26955 ba5c830ca42b6a419c383562f2767228 232 Gene3D G3DSA:3.40.630.40 27 231 2.6E-32 T 14-10-2018 LH59_26955 ba5c830ca42b6a419c383562f2767228 232 SUPERFAMILY SSF53187 29 228 8.79E-29 T 14-10-2018 LH59_26955 ba5c830ca42b6a419c383562f2767228 232 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 30 227 6.6E-35 T 14-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 LH59_26955 ba5c830ca42b6a419c383562f2767228 232 SMART SM00646 89 227 3.6E-7 T 14-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 LH59_05380 f2cd96d4bba18debbd30c4171c241fff 325 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 162 270 4.6E-12 T 14-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 LH59_05380 f2cd96d4bba18debbd30c4171c241fff 325 SUPERFAMILY SSF53756 24 309 2.98E-32 T 14-10-2018 LH59_05380 f2cd96d4bba18debbd30c4171c241fff 325 Gene3D G3DSA:3.40.50.2000 154 293 1.2E-20 T 14-10-2018 LH59_03430 02d914067f6e0a85a9444abe78bcbe5a 189 SUPERFAMILY SSF52499 2 186 3.14E-33 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 LH59_03430 02d914067f6e0a85a9444abe78bcbe5a 189 Gene3D G3DSA:3.40.50.850 1 189 5.7E-35 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 LH59_03430 02d914067f6e0a85a9444abe78bcbe5a 189 Pfam PF00857 Isochorismatase family 4 149 3.0E-25 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 LH59_27350 44cffc099a316144b39d900a4aa4a450 631 PIRSF PIRSF001589 1 630 1.4E-123 T 14-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 LH59_27350 44cffc099a316144b39d900a4aa4a450 631 Pfam PF00733 Asparagine synthase 248 624 1.6E-63 T 14-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 LH59_27350 44cffc099a316144b39d900a4aa4a450 631 SUPERFAMILY SSF52402 226 623 2.45E-50 T 14-10-2018 LH59_27350 44cffc099a316144b39d900a4aa4a450 631 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 563 3.6E-120 T 14-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 LH59_27350 44cffc099a316144b39d900a4aa4a450 631 Pfam PF13537 Glutamine amidotransferase domain 52 170 1.2E-44 T 14-10-2018 IPR017932 Glutamine amidotransferase type 2 domain LH59_27350 44cffc099a316144b39d900a4aa4a450 631 SUPERFAMILY SSF56235 1 219 7.81E-56 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal LH59_27350 44cffc099a316144b39d900a4aa4a450 631 Gene3D G3DSA:3.60.20.10 9 193 5.1E-58 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal LH59_19485 8fcd747cd8e7825b6d51189d02fed74f 246 Pfam PF00005 ABC transporter 17 153 7.2E-22 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_19485 8fcd747cd8e7825b6d51189d02fed74f 246 SMART SM00382 26 201 5.9E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_19485 8fcd747cd8e7825b6d51189d02fed74f 246 Gene3D G3DSA:3.40.50.300 1 235 8.5E-56 T 14-10-2018 LH59_19485 8fcd747cd8e7825b6d51189d02fed74f 246 SUPERFAMILY SSF52540 2 201 7.11E-51 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_19485 8fcd747cd8e7825b6d51189d02fed74f 246 ProSitePatterns PS00211 ABC transporters family signature. 125 139 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_06845 fc49fdad61abe13577ed58e88e570a44 171 Pfam PF06271 RDD family 12 157 9.4E-20 T 14-10-2018 IPR010432 RDD LH59_01955 0dc4b779df92f9146efb711e21541dd0 322 SUPERFAMILY SSF53850 110 284 7.33E-14 T 14-10-2018 LH59_01955 0dc4b779df92f9146efb711e21541dd0 322 PIRSF PIRSF017082 5 321 1.1E-94 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_01955 0dc4b779df92f9146efb711e21541dd0 322 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 317 5.8E-90 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_01955 0dc4b779df92f9146efb711e21541dd0 322 Gene3D G3DSA:3.40.190.10 123 246 8.6E-118 T 14-10-2018 LH59_01955 0dc4b779df92f9146efb711e21541dd0 322 Gene3D G3DSA:3.40.190.150 26 311 8.6E-118 T 14-10-2018 LH59_20220 ca5e31294f0c569a51a8b6c68d8c42b4 347 Pfam PF00581 Rhodanese-like domain 15 125 2.2E-8 T 14-10-2018 IPR001763 Rhodanese-like domain LH59_20220 ca5e31294f0c569a51a8b6c68d8c42b4 347 SUPERFAMILY SSF52821 17 129 7.86E-20 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily LH59_20220 ca5e31294f0c569a51a8b6c68d8c42b4 347 SMART SM00450 1 129 1.9E-10 T 14-10-2018 IPR001763 Rhodanese-like domain LH59_20220 ca5e31294f0c569a51a8b6c68d8c42b4 347 Gene3D G3DSA:3.40.50.300 140 318 1.8E-5 T 14-10-2018 LH59_20220 ca5e31294f0c569a51a8b6c68d8c42b4 347 Gene3D G3DSA:3.40.250.10 11 130 1.5E-31 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily LH59_20220 ca5e31294f0c569a51a8b6c68d8c42b4 347 SUPERFAMILY SSF52540 139 306 2.16E-8 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_20220 ca5e31294f0c569a51a8b6c68d8c42b4 347 TIGRFAM TIGR03167 tRNA_sel_U_synt: tRNA 2-selenouridine synthase 14 318 1.6E-104 T 14-10-2018 IPR017582 tRNA 2-selenouridine/geranyl-2-thiouridine synthase GO:0016785|GO:0043828|GO:0070329 LH59_17275 d4bf6c7ffb32d48a3950113cafdfc57f 95 Pfam PF10711 Hypothetical protein (DUF2513) 3 82 3.0E-7 T 14-10-2018 IPR019650 Protein of unknown function DUF2513 LH59_20660 73c61a998cf1b74bb0c74ef4b708b982 161 SUPERFAMILY SSF55729 5 148 5.06E-29 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_20660 73c61a998cf1b74bb0c74ef4b708b982 161 Pfam PF00583 Acetyltransferase (GNAT) family 21 136 7.9E-12 T 14-10-2018 IPR000182 GNAT domain LH59_20660 73c61a998cf1b74bb0c74ef4b708b982 161 Gene3D G3DSA:3.40.630.30 3 160 8.3E-29 T 14-10-2018 LH59_01210 66180e91b4cc00242059aa3f20cf230d 353 Gene3D G3DSA:3.40.50.2000 157 333 5.2E-47 T 14-10-2018 LH59_01210 66180e91b4cc00242059aa3f20cf230d 353 SUPERFAMILY SSF53756 2 349 3.18E-58 T 14-10-2018 LH59_01210 66180e91b4cc00242059aa3f20cf230d 353 Pfam PF00534 Glycosyl transferases group 1 172 327 1.5E-23 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 LH59_01210 66180e91b4cc00242059aa3f20cf230d 353 Gene3D G3DSA:3.40.50.2000 14 343 5.2E-47 T 14-10-2018 LH59_01210 66180e91b4cc00242059aa3f20cf230d 353 Pfam PF13439 Glycosyltransferase Family 4 13 154 3.0E-12 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 LH59_27255 02f9bee79fbef329fd9fda1d44f637ef 318 Pfam PF02470 MlaD protein 42 111 3.4E-11 T 14-10-2018 IPR003399 Mce/MlaD LH59_23125 68b9d60d6f34a8f4d71a67651e9e3c79 498 Pfam PF03929 PepSY-associated TM region 14 491 8.3E-18 T 14-10-2018 IPR005625 PepSY-associated TM protein LH59_08145 91dc888ca2c00d642690b71020ac6e78 212 Pfam PF13590 Domain of unknown function (DUF4136) 36 199 4.1E-26 T 14-10-2018 IPR025411 Domain of unknown function DUF4136 LH59_08145 91dc888ca2c00d642690b71020ac6e78 212 Gene3D G3DSA:3.30.160.670 34 198 7.2E-9 T 14-10-2018 LH59_03620 dade0fd9cb0b9af09d81313724c787a7 155 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 17 145 6.9E-50 T 14-10-2018 IPR003791 Protein of unknown function UPF0178 LH59_03620 dade0fd9cb0b9af09d81313724c787a7 155 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 1 147 32.157 T 14-10-2018 IPR003791 Protein of unknown function UPF0178 LH59_13220 6c0ce124b9caa5b3300b3eab21ec435b 278 SUPERFAMILY SSF52402 1 143 1.0E-12 T 14-10-2018 LH59_13220 6c0ce124b9caa5b3300b3eab21ec435b 278 Pfam PF00582 Universal stress protein family 1 143 3.0E-7 T 14-10-2018 IPR006016 UspA LH59_13220 6c0ce124b9caa5b3300b3eab21ec435b 278 Pfam PF00582 Universal stress protein family 153 275 1.5E-9 T 14-10-2018 IPR006016 UspA LH59_13220 6c0ce124b9caa5b3300b3eab21ec435b 278 SUPERFAMILY SSF52402 153 275 1.09E-18 T 14-10-2018 LH59_13220 6c0ce124b9caa5b3300b3eab21ec435b 278 Gene3D G3DSA:3.40.50.12370 4 277 1.4E-29 T 14-10-2018 LH59_13220 6c0ce124b9caa5b3300b3eab21ec435b 278 PRINTS PR01438 Universal stress protein signature 238 250 2.8E-6 T 14-10-2018 IPR006015 Universal stress protein A LH59_13220 6c0ce124b9caa5b3300b3eab21ec435b 278 PRINTS PR01438 Universal stress protein signature 256 278 2.8E-6 T 14-10-2018 IPR006015 Universal stress protein A LH59_13220 6c0ce124b9caa5b3300b3eab21ec435b 278 PRINTS PR01438 Universal stress protein signature 152 170 2.8E-6 T 14-10-2018 IPR006015 Universal stress protein A LH59_12375 9caec2a5e64c162e3423f41d4dcddb10 202 Gene3D G3DSA:1.20.120.1490 65 177 1.3E-6 T 14-10-2018 LH59_08025 c3f1e0ec49d03997d56d240b7bd053ea 270 SUPERFAMILY SSF69618 11 254 3.66E-32 T 14-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LH59_08025 c3f1e0ec49d03997d56d240b7bd053ea 270 Gene3D G3DSA:3.40.50.10090 142 267 1.6E-19 T 14-10-2018 LH59_08025 c3f1e0ec49d03997d56d240b7bd053ea 270 Pfam PF02602 Uroporphyrinogen-III synthase HemD 23 235 1.5E-25 T 14-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 LH59_08025 c3f1e0ec49d03997d56d240b7bd053ea 270 Gene3D G3DSA:3.40.50.10090 3 138 5.0E-20 T 14-10-2018 LH59_24405 f988d87d30cf46e2ee97d88e09f78403 176 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 10 151 26.332 T 14-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 LH59_24405 f988d87d30cf46e2ee97d88e09f78403 176 SUPERFAMILY SSF52121 7 151 1.44E-49 T 14-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 LH59_24405 f988d87d30cf46e2ee97d88e09f78403 176 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 14 148 1.0E-47 T 14-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 LH59_24405 f988d87d30cf46e2ee97d88e09f78403 176 Gene3D G3DSA:3.40.50.960 4 151 1.3E-49 T 14-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 LH59_24405 f988d87d30cf46e2ee97d88e09f78403 176 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 16 147 7.1E-37 T 14-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 LH59_11870 ef1f4f3734abe09339728dad876f8aaa 270 Gene3D G3DSA:3.90.640.20 175 270 4.0E-26 T 14-10-2018 IPR037126 PdaC/RsiV-like superfamily LH59_11870 ef1f4f3734abe09339728dad876f8aaa 270 Pfam PF11738 Protein of unknown function (DUF3298) 209 256 1.5E-11 T 14-10-2018 IPR021729 Domain of unknown function DUF3298 LH59_11870 ef1f4f3734abe09339728dad876f8aaa 270 Gene3D G3DSA:3.30.565.40 44 174 4.1E-21 T 14-10-2018 LH59_22845 fe66f2ebeaeb43b02fba73a557a146e8 293 SUPERFAMILY SSF103481 194 291 5.62E-7 T 14-10-2018 LH59_22845 fe66f2ebeaeb43b02fba73a557a146e8 293 SUPERFAMILY SSF103481 41 139 3.01E-7 T 14-10-2018 LH59_23840 3630029af05bcc30bebc2245b7863b98 296 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 210 8.3E-12 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 LH59_23840 3630029af05bcc30bebc2245b7863b98 296 Gene3D G3DSA:3.40.50.720 2 295 2.1E-37 T 14-10-2018 LH59_23840 3630029af05bcc30bebc2245b7863b98 296 SUPERFAMILY SSF51735 1 285 1.54E-39 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_06290 2545c10b5a035780026dd662d1966a78 185 PIRSF PIRSF016661 1 183 4.3E-46 T 14-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 LH59_06290 2545c10b5a035780026dd662d1966a78 185 Pfam PF02632 BioY family 30 177 2.9E-38 T 14-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 LH59_06290 2545c10b5a035780026dd662d1966a78 185 Gene3D G3DSA:1.10.1760.20 1 180 4.3E-57 T 14-10-2018 LH59_12265 4741ed5e94c8fa4e2171fdb71e11b553 112 Pfam PF03334 Na+/H+ antiporter subunit 16 96 3.3E-20 T 14-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 LH59_12265 4741ed5e94c8fa4e2171fdb71e11b553 112 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 15 104 1.5E-21 T 14-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 LH59_18235 b4299e44f41933b504c9c72c05c13330 417 Pfam PF00012 Hsp70 protein 275 392 3.3E-13 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LH59_18235 b4299e44f41933b504c9c72c05c13330 417 Pfam PF00012 Hsp70 protein 6 226 2.5E-13 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LH59_18235 b4299e44f41933b504c9c72c05c13330 417 SUPERFAMILY SSF53067 5 172 1.13E-28 T 14-10-2018 LH59_18235 b4299e44f41933b504c9c72c05c13330 417 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 180 193 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 LH59_18235 b4299e44f41933b504c9c72c05c13330 417 Gene3D G3DSA:3.30.420.40 4 185 6.9E-34 T 14-10-2018 LH59_18235 b4299e44f41933b504c9c72c05c13330 417 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 370 384 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 LH59_18235 b4299e44f41933b504c9c72c05c13330 417 SUPERFAMILY SSF53067 175 412 6.33E-34 T 14-10-2018 LH59_18235 b4299e44f41933b504c9c72c05c13330 417 PRINTS PR00301 70kDa heat shock protein signature 186 196 2.0E-6 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LH59_18235 b4299e44f41933b504c9c72c05c13330 417 PRINTS PR00301 70kDa heat shock protein signature 120 140 2.0E-6 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LH59_18235 b4299e44f41933b504c9c72c05c13330 417 PRINTS PR00301 70kDa heat shock protein signature 32 44 2.0E-6 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LH59_18235 b4299e44f41933b504c9c72c05c13330 417 PRINTS PR00301 70kDa heat shock protein signature 4 17 2.0E-6 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 LH59_18235 b4299e44f41933b504c9c72c05c13330 417 Gene3D G3DSA:3.30.420.40 319 397 8.0E-8 T 14-10-2018 LH59_17185 f4118a8b3020e2728336b25e8b76fc5f 134 SUPERFAMILY SSF82649 2 126 5.49E-48 T 14-10-2018 LH59_17185 f4118a8b3020e2728336b25e8b76fc5f 134 Pfam PF01592 NifU-like N terminal domain 3 125 1.8E-56 T 14-10-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 LH59_17185 f4118a8b3020e2728336b25e8b76fc5f 134 TIGRFAM TIGR01999 iscU: FeS cluster assembly scaffold IscU 3 125 6.5E-69 T 14-10-2018 IPR011339 ISC system FeS cluster assembly, IscU scaffold GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 LH59_17185 f4118a8b3020e2728336b25e8b76fc5f 134 Gene3D G3DSA:3.90.1010.10 1 131 4.9E-58 T 14-10-2018 LH59_00655 b5a30ddd32bec58da4d89a98d11187d6 266 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 256 1.6E-12 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_00655 b5a30ddd32bec58da4d89a98d11187d6 266 Gene3D G3DSA:1.10.3720.10 5 258 3.3E-57 T 14-10-2018 IPR035906 MetI-like superfamily LH59_00655 b5a30ddd32bec58da4d89a98d11187d6 266 SUPERFAMILY SSF161098 7 265 2.49E-60 T 14-10-2018 IPR035906 MetI-like superfamily LH59_13665 63f92e3b8047c8f1a0b0b92397c17ec8 283 Gene3D G3DSA:3.90.850.10 66 282 6.4E-80 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 LH59_13665 63f92e3b8047c8f1a0b0b92397c17ec8 283 Pfam PF10370 Domain of unknown function (DUF2437) 1 65 1.0E-5 T 14-10-2018 IPR018833 Domain of unknown function DUF2437 LH59_13665 63f92e3b8047c8f1a0b0b92397c17ec8 283 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 71 276 2.9E-67 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 LH59_13665 63f92e3b8047c8f1a0b0b92397c17ec8 283 SUPERFAMILY SSF56529 59 277 3.4E-79 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 LH59_10240 dcfef57664389a0e49a61516ee4cb448 303 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 168 1.2E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10240 dcfef57664389a0e49a61516ee4cb448 303 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 234 254 1.2E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10240 dcfef57664389a0e49a61516ee4cb448 303 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 27 44 1.2E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10240 dcfef57664389a0e49a61516ee4cb448 303 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 198 215 1.2E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10240 dcfef57664389a0e49a61516ee4cb448 303 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 105 116 1.2E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10240 dcfef57664389a0e49a61516ee4cb448 303 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 196 1.2E-25 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10240 dcfef57664389a0e49a61516ee4cb448 303 Gene3D G3DSA:3.40.50.720 10 283 1.5E-76 T 14-10-2018 LH59_10240 dcfef57664389a0e49a61516ee4cb448 303 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 35 270 2.2E-49 T 14-10-2018 LH59_10240 dcfef57664389a0e49a61516ee4cb448 303 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 26 171 7.1E-4 T 14-10-2018 LH59_10240 dcfef57664389a0e49a61516ee4cb448 303 SUPERFAMILY SSF51735 24 270 1.42E-67 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_24335 7d6c9e83e066d12eb0ae666cbd7891b0 333 SUPERFAMILY SSF51556 4 332 2.2E-76 T 14-10-2018 IPR032466 Metal-dependent hydrolase LH59_24335 7d6c9e83e066d12eb0ae666cbd7891b0 333 Gene3D G3DSA:3.20.20.140 2 333 3.3E-99 T 14-10-2018 LH59_24335 7d6c9e83e066d12eb0ae666cbd7891b0 333 Pfam PF04909 Amidohydrolase 5 331 2.6E-47 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 LH59_14600 493b8a3d9e1b34615ab1d081cfb0d284 473 Pfam PF07687 Peptidase dimerisation domain 203 355 2.6E-10 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain LH59_14600 493b8a3d9e1b34615ab1d081cfb0d284 473 SUPERFAMILY SSF53187 19 455 2.89E-47 T 14-10-2018 LH59_14600 493b8a3d9e1b34615ab1d081cfb0d284 473 Gene3D G3DSA:3.40.630.10 52 435 6.5E-85 T 14-10-2018 LH59_14600 493b8a3d9e1b34615ab1d081cfb0d284 473 Gene3D G3DSA:3.30.70.360 205 368 6.5E-85 T 14-10-2018 LH59_14600 493b8a3d9e1b34615ab1d081cfb0d284 473 Pfam PF01546 Peptidase family M20/M25/M40 89 450 8.7E-22 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 LH59_22865 e600799c070f1ca64a4473326ce001e6 294 SUPERFAMILY SSF53474 55 289 1.07E-45 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_22865 e600799c070f1ca64a4473326ce001e6 294 Pfam PF01738 Dienelactone hydrolase family 65 289 4.6E-62 T 14-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 LH59_22865 e600799c070f1ca64a4473326ce001e6 294 Gene3D G3DSA:3.40.50.1820 49 289 5.9E-60 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_13765 5d82b44f764bcdfbfb6f5b53967eca48 364 SUPERFAMILY SSF56281 83 332 7.34E-36 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like LH59_13765 5d82b44f764bcdfbfb6f5b53967eca48 364 Gene3D G3DSA:3.60.15.10 78 336 3.7E-80 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like LH59_13765 5d82b44f764bcdfbfb6f5b53967eca48 364 Pfam PF12706 Beta-lactamase superfamily domain 100 292 2.1E-45 T 14-10-2018 IPR001279 Metallo-beta-lactamase LH59_11915 e615302891681a48425f09acba7d184f 107 SUPERFAMILY SSF48452 4 78 1.01E-10 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_11915 e615302891681a48425f09acba7d184f 107 Gene3D G3DSA:1.25.40.10 1 106 3.4E-23 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_19550 da60e1141c81efdb1f6de163c2c5c686 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 255 1.9E-57 T 14-10-2018 LH59_19550 da60e1141c81efdb1f6de163c2c5c686 256 Gene3D G3DSA:3.40.50.720 1 255 8.4E-71 T 14-10-2018 LH59_19550 da60e1141c81efdb1f6de163c2c5c686 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 LH59_19550 da60e1141c81efdb1f6de163c2c5c686 256 SUPERFAMILY SSF51735 6 255 2.22E-71 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_19550 da60e1141c81efdb1f6de163c2c5c686 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 5.0E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_19550 da60e1141c81efdb1f6de163c2c5c686 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 5.0E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_19550 da60e1141c81efdb1f6de163c2c5c686 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 5.0E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_19550 da60e1141c81efdb1f6de163c2c5c686 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 5.1E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_19550 da60e1141c81efdb1f6de163c2c5c686 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 5.1E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_19550 da60e1141c81efdb1f6de163c2c5c686 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 5.1E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_19550 da60e1141c81efdb1f6de163c2c5c686 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 5.1E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_19550 da60e1141c81efdb1f6de163c2c5c686 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 5.1E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_19550 da60e1141c81efdb1f6de163c2c5c686 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 5.1E-38 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR LH59_10210 e98425ad4321e00037cdff87d61a2ff7 295 SUPERFAMILY SSF103481 192 287 2.88E-13 T 14-10-2018 LH59_10210 e98425ad4321e00037cdff87d61a2ff7 295 Pfam PF00892 EamA-like transporter family 7 133 6.3E-20 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_10210 e98425ad4321e00037cdff87d61a2ff7 295 Pfam PF00892 EamA-like transporter family 150 286 1.7E-16 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_10210 e98425ad4321e00037cdff87d61a2ff7 295 SUPERFAMILY SSF103481 39 135 1.29E-15 T 14-10-2018 LH59_21470 1cd9fc8b97ebcc7caeb33bff14d4d451 254 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 227 248 8.3E-5 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal LH59_21470 1cd9fc8b97ebcc7caeb33bff14d4d451 254 Gene3D G3DSA:3.40.50.300 3 249 1.2E-58 T 14-10-2018 LH59_21470 1cd9fc8b97ebcc7caeb33bff14d4d451 254 SUPERFAMILY SSF52540 7 240 3.03E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_21470 1cd9fc8b97ebcc7caeb33bff14d4d451 254 SMART SM00382 32 226 8.6E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_21470 1cd9fc8b97ebcc7caeb33bff14d4d451 254 Pfam PF00005 ABC transporter 23 177 1.8E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_27525 c4d7e516c530d38aa1d12ebee8d9e178 292 Pfam PF00487 Fatty acid desaturase 32 249 1.2E-20 T 14-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 LH59_15555 5bac417e453fcaa087725970d312971f 370 TIGRFAM TIGR03363 VI_chp_8: type VI secretion-associated protein, ImpA family 3 361 9.5E-117 T 14-10-2018 IPR017740 Type VI secretion system-associated, ImpA LH59_15555 5bac417e453fcaa087725970d312971f 370 Pfam PF06812 ImpA, N-terminal, type VI secretion system 8 130 2.4E-39 T 14-10-2018 IPR010657 ImpA, N-terminal LH59_19750 7210aadd7c50a13851d99c06a1bb4137 371 TIGRFAM TIGR03837 efp_adjacent_2: conserved hypothetical protein, PP_1857 family 4 365 6.0E-135 T 14-10-2018 IPR016633 Uncharacterised conserved protein UCP015557 LH59_19750 7210aadd7c50a13851d99c06a1bb4137 371 PIRSF PIRSF015557 1 369 1.6E-137 T 14-10-2018 IPR016633 Uncharacterised conserved protein UCP015557 LH59_19750 7210aadd7c50a13851d99c06a1bb4137 371 Pfam PF10093 Uncharacterized protein conserved in bacteria (DUF2331) 4 364 6.9E-132 T 14-10-2018 IPR016633 Uncharacterised conserved protein UCP015557 LH59_27425 12f0fb146ede75be856ab676b2a0cce9 411 Pfam PF13480 Acetyltransferase (GNAT) domain 191 317 3.6E-14 T 14-10-2018 IPR038740 BioF2-like, acetyltransferase domain KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 LH59_27425 12f0fb146ede75be856ab676b2a0cce9 411 Gene3D G3DSA:3.40.630.30 162 346 3.5E-25 T 14-10-2018 LH59_27425 12f0fb146ede75be856ab676b2a0cce9 411 SUPERFAMILY SSF55729 193 346 3.98E-25 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_04015 e365d33de7dc1a01b53f7e1a519bb804 96 Pfam PF04999 Cell division protein FtsL 2 82 3.1E-18 T 14-10-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 LH59_04015 e365d33de7dc1a01b53f7e1a519bb804 96 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 1 83 4.7E-25 T 14-10-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 LH59_04015 e365d33de7dc1a01b53f7e1a519bb804 96 Hamap MF_00910 Cell division protein FtsL [ftsL]. 1 84 14.826 T 14-10-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 LH59_03710 6985bc8f60c564a21796b110934fda63 295 SUPERFAMILY SSF53474 24 285 1.17E-45 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_03710 6985bc8f60c564a21796b110934fda63 295 Gene3D G3DSA:3.40.50.1820 26 285 1.5E-42 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_03710 6985bc8f60c564a21796b110934fda63 295 PRINTS PR00111 Alpha/beta hydrolase fold signature 154 167 1.5E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_03710 6985bc8f60c564a21796b110934fda63 295 PRINTS PR00111 Alpha/beta hydrolase fold signature 107 122 1.5E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_03710 6985bc8f60c564a21796b110934fda63 295 Pfam PF12146 Serine aminopeptidase, S33 81 195 7.6E-17 T 14-10-2018 IPR022742 Serine aminopeptidase, S33 LH59_21285 7b45b6f237739a602035446e86f41e69 503 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 218 481 22.579 T 14-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 LH59_21285 7b45b6f237739a602035446e86f41e69 503 SUPERFAMILY SSF53335 207 475 3.57E-65 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_21285 7b45b6f237739a602035446e86f41e69 503 SUPERFAMILY SSF103473 2 191 6.15E-7 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_21285 7b45b6f237739a602035446e86f41e69 503 Gene3D G3DSA:3.40.50.150 260 495 7.0E-59 T 14-10-2018 LH59_21285 7b45b6f237739a602035446e86f41e69 503 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 285 298 - T 14-10-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 LH59_21285 7b45b6f237739a602035446e86f41e69 503 Pfam PF01564 Spermine/spermidine synthase domain 264 440 1.0E-29 T 14-10-2018 LH59_03695 6c142e70e8bd19ab68a8ab70c6f02431 239 Pfam PF00005 ABC transporter 26 167 7.7E-24 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_03695 6c142e70e8bd19ab68a8ab70c6f02431 239 SUPERFAMILY SSF52540 10 231 1.31E-53 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_03695 6c142e70e8bd19ab68a8ab70c6f02431 239 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_03695 6c142e70e8bd19ab68a8ab70c6f02431 239 Gene3D G3DSA:3.40.50.300 7 238 1.2E-52 T 14-10-2018 LH59_03695 6c142e70e8bd19ab68a8ab70c6f02431 239 SMART SM00382 35 218 5.7E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_03475 ff3b87e1f32d18449522c9d874c39adc 126 SUPERFAMILY SSF55331 2 125 1.08E-39 T 14-10-2018 IPR014347 Tautomerase/MIF superfamily LH59_03475 ff3b87e1f32d18449522c9d874c39adc 126 Gene3D G3DSA:3.30.429.10 2 126 1.2E-43 T 14-10-2018 IPR014347 Tautomerase/MIF superfamily LH59_03475 ff3b87e1f32d18449522c9d874c39adc 126 Pfam PF14552 Tautomerase enzyme 38 119 4.9E-30 T 14-10-2018 IPR037479 Tautomerase, MSAD family LH59_15680 2e511d0010050b4b716b3ff52a657092 291 SUPERFAMILY SSF53850 94 288 2.17E-24 T 14-10-2018 LH59_15680 2e511d0010050b4b716b3ff52a657092 291 Pfam PF03466 LysR substrate binding domain 90 282 8.3E-18 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_15680 2e511d0010050b4b716b3ff52a657092 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 2.9E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_15680 2e511d0010050b4b716b3ff52a657092 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 2.9E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_15680 2e511d0010050b4b716b3ff52a657092 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 2.9E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_15680 2e511d0010050b4b716b3ff52a657092 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 9.8E-20 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_15680 2e511d0010050b4b716b3ff52a657092 291 Gene3D G3DSA:1.10.10.10 1 85 1.1E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_15680 2e511d0010050b4b716b3ff52a657092 291 SUPERFAMILY SSF46785 4 86 7.69E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_15680 2e511d0010050b4b716b3ff52a657092 291 Gene3D G3DSA:3.40.190.290 94 255 4.0E-24 T 14-10-2018 LH59_01455 7cce41a7d9e079cff3d0dfcc6c6fe611 474 PIRSF PIRSF002744 1 468 1.1E-100 T 14-10-2018 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 LH59_01455 7cce41a7d9e079cff3d0dfcc6c6fe611 474 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 21 442 3.2E-50 T 14-10-2018 IPR001248 Purine-cytosine permease GO:0016020|GO:0022857|GO:0055085 LH59_01455 7cce41a7d9e079cff3d0dfcc6c6fe611 474 Gene3D G3DSA:1.10.4160.10 11 451 1.2E-47 T 14-10-2018 IPR038271 Purine-cytosine permease superfamily LH59_19010 1ced360d71a872417ffb7d2931323d56 120 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 36 72 1.9E-5 T 14-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM LH59_19010 1ced360d71a872417ffb7d2931323d56 120 SUPERFAMILY SSF143120 30 70 3.14E-5 T 14-10-2018 IPR036165 YefM-like superfamily LH59_23115 9340ed2c8172d19ffce80efed6229d5c 132 Pfam PF11162 Protein of unknown function (DUF2946) 12 130 9.6E-15 T 14-10-2018 IPR021333 Protein of unknown function DUF2946 LH59_25800 3b1ebe5d76da135168729b7b5a96c6ad 445 SUPERFAMILY SSF51735 14 150 1.21E-23 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_25800 3b1ebe5d76da135168729b7b5a96c6ad 445 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 57 133 1.7E-6 T 14-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 LH59_25800 3b1ebe5d76da135168729b7b5a96c6ad 445 SMART SM00858 361 426 5.4E-5 T 14-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 LH59_25800 3b1ebe5d76da135168729b7b5a96c6ad 445 Gene3D G3DSA:3.40.50.720 10 182 1.2E-22 T 14-10-2018 LH59_08605 65cdbd09a434a4fec67eeb4d8b5b4c22 166 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 28 151 7.5E-29 T 14-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ LH59_25270 8c4b3e27b12e0ae142f0f69ff895bd66 401 Gene3D G3DSA:3.20.20.120 119 371 2.5E-76 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily LH59_25270 8c4b3e27b12e0ae142f0f69ff895bd66 401 SUPERFAMILY SSF54826 27 124 1.27E-13 T 14-10-2018 LH59_25270 8c4b3e27b12e0ae142f0f69ff895bd66 401 SMART SM00922 146 258 2.5E-13 T 14-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal LH59_25270 8c4b3e27b12e0ae142f0f69ff895bd66 401 Gene3D G3DSA:3.30.390.10 27 387 2.5E-76 T 14-10-2018 IPR029017 Enolase-like, N-terminal LH59_25270 8c4b3e27b12e0ae142f0f69ff895bd66 401 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 35 124 8.8E-6 T 14-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain LH59_25270 8c4b3e27b12e0ae142f0f69ff895bd66 401 SUPERFAMILY SSF51604 112 387 1.17E-53 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily LH59_25270 8c4b3e27b12e0ae142f0f69ff895bd66 401 Pfam PF13378 Enolase C-terminal domain-like 152 381 1.6E-43 T 14-10-2018 IPR029065 Enolase C-terminal domain-like LH59_26825 44cfc8881e0385d05d72c7d8c5fe7831 290 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 274 5.9E-34 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_08190 25ea08d4eaa8b6e213a54692ed582f6b 105 Pfam PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch 11 94 2.8E-35 T 14-10-2018 IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 LH59_21960 12b43d911b0865a8f6231795ca3aeb53 441 Pfam PF13343 Bacterial extracellular solute-binding protein 75 283 6.2E-21 T 14-10-2018 LH59_21960 12b43d911b0865a8f6231795ca3aeb53 441 Gene3D G3DSA:3.40.190.10 131 247 6.3E-43 T 14-10-2018 LH59_21960 12b43d911b0865a8f6231795ca3aeb53 441 Gene3D G3DSA:3.40.190.10 29 284 6.3E-43 T 14-10-2018 LH59_21960 12b43d911b0865a8f6231795ca3aeb53 441 SUPERFAMILY SSF53850 22 312 6.73E-46 T 14-10-2018 LH59_01970 5c01daffcfbc89f3f8c12d53df69d1d0 330 PIRSF PIRSF017082 1 329 4.2E-81 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_01970 5c01daffcfbc89f3f8c12d53df69d1d0 330 Gene3D G3DSA:3.40.190.150 36 320 7.2E-113 T 14-10-2018 LH59_01970 5c01daffcfbc89f3f8c12d53df69d1d0 330 Gene3D G3DSA:3.40.190.10 133 255 7.2E-113 T 14-10-2018 LH59_01970 5c01daffcfbc89f3f8c12d53df69d1d0 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 56 323 2.4E-86 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_01970 5c01daffcfbc89f3f8c12d53df69d1d0 330 SUPERFAMILY SSF53850 119 298 2.14E-11 T 14-10-2018 LH59_12350 d535f564b8a8c1116337ecaa7e5735d9 213 Pfam PF02660 Glycerol-3-phosphate acyltransferase 17 199 2.0E-52 T 14-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 LH59_12350 d535f564b8a8c1116337ecaa7e5735d9 213 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 13 208 20.868 T 14-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 LH59_12350 d535f564b8a8c1116337ecaa7e5735d9 213 SMART SM01207 16 200 5.5E-88 T 14-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 LH59_12350 d535f564b8a8c1116337ecaa7e5735d9 213 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 11 207 1.9E-61 T 14-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 LH59_00835 ce24f417249a6682b01eb77c1514031a 300 Pfam PF03466 LysR substrate binding domain 94 297 7.6E-37 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_00835 ce24f417249a6682b01eb77c1514031a 300 Gene3D G3DSA:1.10.10.10 9 99 2.1E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_00835 ce24f417249a6682b01eb77c1514031a 300 Gene3D G3DSA:3.40.190.10 106 293 1.9E-50 T 14-10-2018 LH59_00835 ce24f417249a6682b01eb77c1514031a 300 SUPERFAMILY SSF53850 96 299 6.88E-37 T 14-10-2018 LH59_00835 ce24f417249a6682b01eb77c1514031a 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 25 36 2.9E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_00835 ce24f417249a6682b01eb77c1514031a 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 36 46 2.9E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_00835 ce24f417249a6682b01eb77c1514031a 300 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 46 57 2.9E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_00835 ce24f417249a6682b01eb77c1514031a 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 69 5.9E-20 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_00835 ce24f417249a6682b01eb77c1514031a 300 SUPERFAMILY SSF46785 9 88 9.1E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_00835 ce24f417249a6682b01eb77c1514031a 300 Gene3D G3DSA:3.40.190.10 166 266 1.9E-50 T 14-10-2018 LH59_08180 5fc0cd80cf89c8cf1e7908a6ec7ca7d0 409 Pfam PF13183 4Fe-4S dicluster domain 22 89 1.1E-12 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain LH59_08180 5fc0cd80cf89c8cf1e7908a6ec7ca7d0 409 SUPERFAMILY SSF54862 21 117 1.17E-19 T 14-10-2018 LH59_08180 5fc0cd80cf89c8cf1e7908a6ec7ca7d0 409 Gene3D G3DSA:1.10.1060.10 12 107 1.1E-8 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 LH59_08180 5fc0cd80cf89c8cf1e7908a6ec7ca7d0 409 Pfam PF02754 Cysteine-rich domain 305 387 2.3E-10 T 14-10-2018 IPR004017 Cysteine-rich domain LH59_08180 5fc0cd80cf89c8cf1e7908a6ec7ca7d0 409 Pfam PF02754 Cysteine-rich domain 169 255 1.7E-8 T 14-10-2018 IPR004017 Cysteine-rich domain LH59_08180 5fc0cd80cf89c8cf1e7908a6ec7ca7d0 409 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 75 86 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site LH59_08180 5fc0cd80cf89c8cf1e7908a6ec7ca7d0 409 PIRSF PIRSF000139 9 408 2.4E-108 T 14-10-2018 LH59_24250 dd047195200accbab4e750855f6ad61d 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 2.0E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_24250 dd047195200accbab4e750855f6ad61d 302 SUPERFAMILY SSF53850 90 297 1.19E-47 T 14-10-2018 LH59_24250 dd047195200accbab4e750855f6ad61d 302 Gene3D G3DSA:3.40.190.10 164 265 1.7E-63 T 14-10-2018 LH59_24250 dd047195200accbab4e750855f6ad61d 302 Gene3D G3DSA:3.40.190.10 91 292 1.7E-63 T 14-10-2018 LH59_24250 dd047195200accbab4e750855f6ad61d 302 Gene3D G3DSA:1.10.10.10 3 88 2.6E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_24250 dd047195200accbab4e750855f6ad61d 302 Pfam PF03466 LysR substrate binding domain 88 294 3.8E-46 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_24250 dd047195200accbab4e750855f6ad61d 302 SUPERFAMILY SSF46785 3 112 4.54E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_03555 8f301fab33195c283ed694b6faf1d711 328 Gene3D G3DSA:3.40.190.150 34 318 5.0E-112 T 14-10-2018 LH59_03555 8f301fab33195c283ed694b6faf1d711 328 SUPERFAMILY SSF53850 108 288 1.86E-12 T 14-10-2018 LH59_03555 8f301fab33195c283ed694b6faf1d711 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 54 324 3.0E-78 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_03555 8f301fab33195c283ed694b6faf1d711 328 PIRSF PIRSF017082 1 328 5.2E-77 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_03555 8f301fab33195c283ed694b6faf1d711 328 Gene3D G3DSA:3.40.190.10 131 253 5.0E-112 T 14-10-2018 LH59_24625 590c26e95988125fd90a955b35373cd3 293 SUPERFAMILY SSF63829 13 288 1.7E-56 T 14-10-2018 LH59_24625 590c26e95988125fd90a955b35373cd3 293 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 15 262 2.8E-72 T 14-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region LH59_24625 590c26e95988125fd90a955b35373cd3 293 Gene3D G3DSA:2.120.10.30 4 293 1.5E-85 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like LH59_24625 590c26e95988125fd90a955b35373cd3 293 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 95 116 2.7E-28 T 14-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) LH59_24625 590c26e95988125fd90a955b35373cd3 293 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 202 219 2.7E-28 T 14-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) LH59_24625 590c26e95988125fd90a955b35373cd3 293 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 16 33 2.7E-28 T 14-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) LH59_24625 590c26e95988125fd90a955b35373cd3 293 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 244 262 2.7E-28 T 14-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) LH59_24625 590c26e95988125fd90a955b35373cd3 293 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 138 160 2.7E-28 T 14-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) LH59_24625 590c26e95988125fd90a955b35373cd3 293 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 161 181 2.7E-28 T 14-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) LH59_27360 299052cbe123e8f5876e49ec315f5308 423 SUPERFAMILY SSF53756 56 395 4.16E-11 T 14-10-2018 LH59_05960 b4c8c2b74da520c70f6103c156c4d9c5 273 SUPERFAMILY SSF161098 65 251 3.66E-24 T 14-10-2018 IPR035906 MetI-like superfamily LH59_05960 b4c8c2b74da520c70f6103c156c4d9c5 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 270 2.5E-26 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_05960 b4c8c2b74da520c70f6103c156c4d9c5 273 Gene3D G3DSA:1.10.3720.10 59 271 2.7E-22 T 14-10-2018 IPR035906 MetI-like superfamily LH59_21345 7386a9c0bf08f0fac06a85bc7f2cefdf 256 Gene3D G3DSA:3.40.50.150 14 252 1.3E-32 T 14-10-2018 LH59_21345 7386a9c0bf08f0fac06a85bc7f2cefdf 256 SUPERFAMILY SSF53335 13 234 3.05E-34 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_28200 872e36a800cbc37b2d71dc277bd23e2a 305 Gene3D G3DSA:1.10.3720.10 91 300 1.4E-25 T 14-10-2018 IPR035906 MetI-like superfamily LH59_28200 872e36a800cbc37b2d71dc277bd23e2a 305 SUPERFAMILY SSF161098 97 287 9.81E-28 T 14-10-2018 IPR035906 MetI-like superfamily LH59_28200 872e36a800cbc37b2d71dc277bd23e2a 305 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 17 62 2.3E-10 T 14-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain LH59_28200 872e36a800cbc37b2d71dc277bd23e2a 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 120 302 7.2E-30 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_14085 9c981c113dbfca5cb3dad316665c5129 615 Pfam PF04183 IucA / IucC family 149 399 7.2E-74 T 14-10-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0019290 LH59_14085 9c981c113dbfca5cb3dad316665c5129 615 Pfam PF06276 Ferric iron reductase FhuF-like transporter 421 576 1.6E-37 T 14-10-2018 IPR022770 Ferric iron reductase FhuF domain LH59_14085 9c981c113dbfca5cb3dad316665c5129 615 Gene3D G3DSA:1.10.510.40 388 595 2.8E-76 T 14-10-2018 LH59_14085 9c981c113dbfca5cb3dad316665c5129 615 Gene3D G3DSA:1.10.274.90 1 139 4.7E-53 T 14-10-2018 LH59_03480 ed872f8361b7ddf8182efa8e8d84291a 234 SUPERFAMILY SSF53448 61 197 1.35E-5 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases LH59_03480 ed872f8361b7ddf8182efa8e8d84291a 234 Pfam PF03407 Nucleotide-diphospho-sugar transferase 84 178 1.3E-7 T 14-10-2018 IPR005069 Nucleotide-diphospho-sugar transferase LH59_26385 bca195f9f4dc21aeb83c5d97cbe4b1b9 180 Hamap MF_00821 Protein-export protein SecB [secB]. 1 153 30.953 T 14-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 LH59_26385 bca195f9f4dc21aeb83c5d97cbe4b1b9 180 SUPERFAMILY SSF54611 7 149 1.46E-46 T 14-10-2018 IPR035958 SecB-like superfamily LH59_26385 bca195f9f4dc21aeb83c5d97cbe4b1b9 180 Pfam PF02556 Preprotein translocase subunit SecB 14 151 1.6E-50 T 14-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 LH59_26385 bca195f9f4dc21aeb83c5d97cbe4b1b9 180 TIGRFAM TIGR00809 secB: protein-export chaperone SecB 15 148 4.4E-43 T 14-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 LH59_26385 bca195f9f4dc21aeb83c5d97cbe4b1b9 180 Gene3D G3DSA:3.10.420.10 1 166 3.5E-51 T 14-10-2018 IPR035958 SecB-like superfamily LH59_26385 bca195f9f4dc21aeb83c5d97cbe4b1b9 180 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 131 149 1.4E-27 T 14-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 LH59_26385 bca195f9f4dc21aeb83c5d97cbe4b1b9 180 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 105 127 1.4E-27 T 14-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 LH59_26385 bca195f9f4dc21aeb83c5d97cbe4b1b9 180 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 81 101 1.4E-27 T 14-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 LH59_26385 bca195f9f4dc21aeb83c5d97cbe4b1b9 180 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 21 38 1.4E-27 T 14-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 LH59_15250 641cbe0329590f43f7c351530960ce46 63 SUPERFAMILY SSF47413 3 61 1.96E-18 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 LH59_15250 641cbe0329590f43f7c351530960ce46 63 Pfam PF01381 Helix-turn-helix 5 57 1.5E-16 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LH59_15250 641cbe0329590f43f7c351530960ce46 63 SMART SM00530 4 59 2.5E-18 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 LH59_15250 641cbe0329590f43f7c351530960ce46 63 Gene3D G3DSA:1.10.260.40 1 62 6.9E-27 T 14-10-2018 LH59_00820 732020a13fb03f96a8b90b7bdaea6f79 297 SUPERFAMILY SSF103481 195 288 4.05E-9 T 14-10-2018 LH59_00820 732020a13fb03f96a8b90b7bdaea6f79 297 Pfam PF00892 EamA-like transporter family 149 286 2.3E-11 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_00820 732020a13fb03f96a8b90b7bdaea6f79 297 Pfam PF00892 EamA-like transporter family 4 134 3.0E-13 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_00820 732020a13fb03f96a8b90b7bdaea6f79 297 SUPERFAMILY SSF103481 35 137 3.79E-14 T 14-10-2018 LH59_19620 319c8fe48127688999dc01e507677a88 311 Gene3D G3DSA:3.20.20.70 2 311 1.2E-127 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_19620 319c8fe48127688999dc01e507677a88 311 Pfam PF05853 beta-keto acid cleavage enzyme 7 303 3.7E-105 T 14-10-2018 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00310+2.3.1.247 LH59_24805 64e116966fd7b02a03205397afcf9087 656 Pfam PF06097 Bacterial protein of unknown function (DUF945) 1 472 6.0E-112 T 14-10-2018 IPR010352 Protein of unknown function DUF945 LH59_24805 64e116966fd7b02a03205397afcf9087 656 Pfam PF10722 Putative bacterial sensory transduction regulator 524 649 1.2E-13 T 14-10-2018 IPR019660 Putative sensory transduction regulator YbjN LH59_00575 d6eae79d7f43b1c6d176d5b8da4cc849 392 Gene3D G3DSA:1.10.540.10 2 125 4.5E-50 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 LH59_00575 d6eae79d7f43b1c6d176d5b8da4cc849 392 Gene3D G3DSA:1.20.140.10 240 392 1.7E-44 T 14-10-2018 LH59_00575 d6eae79d7f43b1c6d176d5b8da4cc849 392 PIRSF PIRSF016578 13 99 0.0052 T 14-10-2018 LH59_00575 d6eae79d7f43b1c6d176d5b8da4cc849 392 PIRSF PIRSF016578 142 392 4.1E-11 T 14-10-2018 LH59_00575 d6eae79d7f43b1c6d176d5b8da4cc849 392 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 129 141 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 LH59_00575 d6eae79d7f43b1c6d176d5b8da4cc849 392 SUPERFAMILY SSF56645 6 247 2.62E-88 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 LH59_00575 d6eae79d7f43b1c6d176d5b8da4cc849 392 Gene3D G3DSA:2.40.110.10 126 239 2.8E-46 T 14-10-2018 LH59_00575 d6eae79d7f43b1c6d176d5b8da4cc849 392 SUPERFAMILY SSF47203 233 388 1.61E-43 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 LH59_00575 d6eae79d7f43b1c6d176d5b8da4cc849 392 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 346 365 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 LH59_00575 d6eae79d7f43b1c6d176d5b8da4cc849 392 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 234 387 1.0E-38 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 LH59_00575 d6eae79d7f43b1c6d176d5b8da4cc849 392 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 12 123 1.7E-38 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 LH59_00575 d6eae79d7f43b1c6d176d5b8da4cc849 392 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 222 2.0E-27 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 LH59_26880 240be3b5f26e61b5fee2c61cb47aa1f3 444 Gene3D G3DSA:3.40.50.2300 41 366 5.2E-73 T 14-10-2018 LH59_26880 240be3b5f26e61b5fee2c61cb47aa1f3 444 SUPERFAMILY SSF53822 34 410 5.72E-46 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_26880 240be3b5f26e61b5fee2c61cb47aa1f3 444 Pfam PF13458 Periplasmic binding protein 32 404 1.3E-76 T 14-10-2018 IPR028081 Leucine-binding protein domain LH59_26880 240be3b5f26e61b5fee2c61cb47aa1f3 444 Gene3D G3DSA:3.40.50.2300 152 294 5.2E-73 T 14-10-2018 LH59_16910 baafb8c55179d4257d05c0a88218db71 845 Pfam PF01564 Spermine/spermidine synthase domain 530 650 5.2E-5 T 14-10-2018 LH59_16910 baafb8c55179d4257d05c0a88218db71 845 SUPERFAMILY SSF53335 473 708 5.24E-37 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_16910 baafb8c55179d4257d05c0a88218db71 845 SUPERFAMILY SSF103473 28 437 1.57E-9 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_16910 baafb8c55179d4257d05c0a88218db71 845 Gene3D G3DSA:1.20.1250.20 22 442 1.3E-5 T 14-10-2018 LH59_16910 baafb8c55179d4257d05c0a88218db71 845 Gene3D G3DSA:3.40.50.150 520 758 1.9E-33 T 14-10-2018 LH59_18680 8257c08039ef484b8a03f1df22e7588f 348 Pfam PF13280 WYL domain 162 343 2.1E-23 T 14-10-2018 IPR026881 WYL domain LH59_10065 ac1d424185ff6011deedaf74a27eeb26 319 SUPERFAMILY SSF51730 37 311 5.1E-48 T 14-10-2018 IPR029041 FAD-linked oxidoreductase-like LH59_10065 ac1d424185ff6011deedaf74a27eeb26 319 Gene3D G3DSA:3.20.20.530 20 313 4.9E-70 T 14-10-2018 LH59_10065 ac1d424185ff6011deedaf74a27eeb26 319 Pfam PF01619 Proline dehydrogenase 44 303 9.2E-21 T 14-10-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 LH59_04510 944cc7e261bf821b21d9a283895e8790 132 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 17 52 1.4E-12 T 14-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal LH59_04510 944cc7e261bf821b21d9a283895e8790 132 Gene3D G3DSA:1.10.12.20 7 55 2.2E-5 T 14-10-2018 LH59_04510 944cc7e261bf821b21d9a283895e8790 132 SUPERFAMILY SSF50249 8 120 1.63E-31 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_04510 944cc7e261bf821b21d9a283895e8790 132 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 54 113 1.0E-18 T 14-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal LH59_27855 29cb88014db3795c81df8cc0f335e667 353 Pfam PF02653 Branched-chain amino acid transport system / permease component 40 313 2.1E-34 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_08570 3bd2bcebb4a4d84a296c9e4754909209 176 Pfam PF02627 Carboxymuconolactone decarboxylase family 42 102 2.8E-10 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 LH59_08570 3bd2bcebb4a4d84a296c9e4754909209 176 Gene3D G3DSA:1.20.1290.10 35 174 9.6E-42 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 LH59_08570 3bd2bcebb4a4d84a296c9e4754909209 176 SUPERFAMILY SSF69118 14 174 2.75E-37 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 LH59_18375 b8859922db7e679093ac8b6fabe9f021 202 Gene3D G3DSA:3.40.50.150 10 162 1.2E-9 T 14-10-2018 LH59_18375 b8859922db7e679093ac8b6fabe9f021 202 SUPERFAMILY SSF53335 78 178 5.31E-11 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_16960 3b0c4c2cd63bfbbdd3a2237e8d1df718 204 Pfam PF00005 ABC transporter 36 157 1.5E-14 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_16960 3b0c4c2cd63bfbbdd3a2237e8d1df718 204 Gene3D G3DSA:3.40.50.300 1 202 2.9E-38 T 14-10-2018 LH59_16960 3b0c4c2cd63bfbbdd3a2237e8d1df718 204 SUPERFAMILY SSF52540 1 198 1.51E-33 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_12095 66ff525c2b2d6b8ecbd8821f08adc15e 102 Pfam PF09928 Predicted small integral membrane protein (DUF2160) 4 102 7.6E-38 T 14-10-2018 IPR018678 Protein of unknown function DUF2160, transmembrane LH59_12260 3fed29d2821529a6fb1d6c78e926f331 93 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 34 85 2.6E-21 T 14-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 LH59_12260 3fed29d2821529a6fb1d6c78e926f331 93 PIRSF PIRSF028784 1 93 9.1E-30 T 14-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 LH59_13240 05a23c8d5eac42dfa7d101f6bacc6d36 367 Pfam PF05359 Domain of Unknown Function (DUF748) 148 283 1.0E-15 T 14-10-2018 IPR008023 Protein of unknown function DUF748 LH59_04160 ad26c005549be7b76a75c65351f8779f 398 Pfam PF07687 Peptidase dimerisation domain 186 282 3.2E-13 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain LH59_04160 ad26c005549be7b76a75c65351f8779f 398 Gene3D G3DSA:3.40.630.10 16 380 3.8E-140 T 14-10-2018 LH59_04160 ad26c005549be7b76a75c65351f8779f 398 Gene3D G3DSA:3.30.70.360 182 296 3.8E-140 T 14-10-2018 LH59_04160 ad26c005549be7b76a75c65351f8779f 398 SUPERFAMILY SSF55031 184 297 2.22E-32 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain LH59_04160 ad26c005549be7b76a75c65351f8779f 398 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 15 382 2.9E-113 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 LH59_04160 ad26c005549be7b76a75c65351f8779f 398 PIRSF PIRSF005962 2 398 5.4E-135 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 LH59_04160 ad26c005549be7b76a75c65351f8779f 398 Pfam PF01546 Peptidase family M20/M25/M40 74 356 3.4E-37 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 LH59_04160 ad26c005549be7b76a75c65351f8779f 398 SUPERFAMILY SSF53187 3 395 1.0E-88 T 14-10-2018 LH59_16625 8842661334304bd78eb198cc40d654e1 183 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 42 172 2.6E-32 T 14-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ LH59_16880 59420f775ce697cb238844d4c96a1100 166 Pfam PF14316 Domain of unknown function (DUF4381) 9 160 2.5E-28 T 14-10-2018 IPR025489 Protein of unknown function (DUF4381 LH59_06580 3f317980f715530e7928268436511e4e 325 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 34 313 1.1E-38 T 14-10-2018 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0016788 LH59_06580 3f317980f715530e7928268436511e4e 325 PIRSF PIRSF039012 2 319 2.7E-71 T 14-10-2018 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0016788 LH59_06580 3f317980f715530e7928268436511e4e 325 SUPERFAMILY SSF53187 12 313 4.3E-46 T 14-10-2018 LH59_06580 3f317980f715530e7928268436511e4e 325 Gene3D G3DSA:3.40.630.10 3 320 7.6E-80 T 14-10-2018 LH59_05460 5d5d076d682f13b47ce8ffd91bf9bfe4 228 SUPERFAMILY SSF160443 138 221 1.44E-17 T 14-10-2018 IPR036063 Smr domain superfamily LH59_05460 5d5d076d682f13b47ce8ffd91bf9bfe4 228 Pfam PF01713 Smr domain 140 221 1.2E-24 T 14-10-2018 IPR002625 Smr domain LH59_05460 5d5d076d682f13b47ce8ffd91bf9bfe4 228 Gene3D G3DSA:3.30.1370.110 100 225 3.3E-39 T 14-10-2018 LH59_05460 5d5d076d682f13b47ce8ffd91bf9bfe4 228 SMART SM00463 137 221 2.1E-15 T 14-10-2018 IPR002625 Smr domain LH59_27755 995d0eab0ef692a05dde0ae7f422a047 146 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 6 146 19.731 T 14-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 LH59_27755 995d0eab0ef692a05dde0ae7f422a047 146 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 31 145 1.7E-29 T 14-10-2018 IPR021131 Ribosomal protein L18e/L15P LH59_27755 995d0eab0ef692a05dde0ae7f422a047 146 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 5 145 9.4E-48 T 14-10-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_27755 995d0eab0ef692a05dde0ae7f422a047 146 SUPERFAMILY SSF52080 7 144 3.4E-46 T 14-10-2018 IPR036227 Ribosomal L18e/L15P superfamily LH59_27755 995d0eab0ef692a05dde0ae7f422a047 146 Gene3D G3DSA:3.100.10.10 72 146 2.8E-13 T 14-10-2018 LH59_23055 673418af6fb94145d3a672b01bff969f 122 Pfam PF03640 Secreted repeat of unknown function 25 65 3.2E-15 T 14-10-2018 IPR005297 Lipoprotein repeat LH59_23055 673418af6fb94145d3a672b01bff969f 122 Pfam PF03640 Secreted repeat of unknown function 78 121 5.7E-21 T 14-10-2018 IPR005297 Lipoprotein repeat LH59_23055 673418af6fb94145d3a672b01bff969f 122 PIRSF PIRSF029720 1 122 1.0E-50 T 14-10-2018 IPR014558 Uncharacterised conserved lipoprotein LH59_23910 c47865dae7912bc08b6013903ef1e081 119 SUPERFAMILY SSF55961 5 97 1.22E-16 T 14-10-2018 LH59_23910 c47865dae7912bc08b6013903ef1e081 119 Gene3D G3DSA:3.30.530.20 3 70 3.0E-9 T 14-10-2018 IPR023393 START-like domain superfamily LH59_24690 ad68f89ccb73f2fb5ce12203fba289d2 385 Gene3D G3DSA:3.40.50.2000 176 364 2.0E-51 T 14-10-2018 LH59_24690 ad68f89ccb73f2fb5ce12203fba289d2 385 Gene3D G3DSA:3.40.50.2000 70 376 2.0E-51 T 14-10-2018 LH59_24690 ad68f89ccb73f2fb5ce12203fba289d2 385 SUPERFAMILY SSF53756 7 380 3.77E-69 T 14-10-2018 LH59_24690 ad68f89ccb73f2fb5ce12203fba289d2 385 Pfam PF13692 Glycosyl transferases group 1 202 343 3.3E-26 T 14-10-2018 LH59_24690 ad68f89ccb73f2fb5ce12203fba289d2 385 Pfam PF13439 Glycosyltransferase Family 4 18 180 2.7E-11 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 LH59_20270 5a087a9a7f60e4c9e619225ca5cbe9dd 92 Gene3D G3DSA:1.20.210.10 1 79 6.1E-22 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_20270 5a087a9a7f60e4c9e619225ca5cbe9dd 92 SUPERFAMILY SSF81442 1 75 2.75E-12 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_13230 f95aa13f92e980e7c2d8f0361ff61a1f 301 SMART SM00052 10 256 9.2E-63 T 14-10-2018 IPR001633 EAL domain LH59_13230 f95aa13f92e980e7c2d8f0361ff61a1f 301 Gene3D G3DSA:3.20.20.450 17 272 2.3E-72 T 14-10-2018 IPR035919 EAL domain superfamily LH59_13230 f95aa13f92e980e7c2d8f0361ff61a1f 301 Pfam PF00563 EAL domain 25 251 3.2E-60 T 14-10-2018 IPR001633 EAL domain LH59_13230 f95aa13f92e980e7c2d8f0361ff61a1f 301 SUPERFAMILY SSF141868 25 261 1.31E-66 T 14-10-2018 IPR035919 EAL domain superfamily LH59_26600 afd914f1df6f8fa9edc2214297649d7f 524 PIRSF PIRSF006446 2 326 1.3E-113 T 14-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 LH59_26600 afd914f1df6f8fa9edc2214297649d7f 524 PIRSF PIRSF006446 341 523 1.6E-39 T 14-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 LH59_26600 afd914f1df6f8fa9edc2214297649d7f 524 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 9 503 2.2E-177 T 14-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 LH59_24420 617866a5178037e0cc11600993a5cc75 271 Gene3D G3DSA:3.30.450.40 96 266 1.0E-31 T 14-10-2018 IPR029016 GAF-like domain superfamily LH59_24420 617866a5178037e0cc11600993a5cc75 271 SUPERFAMILY SSF46785 18 92 2.08E-10 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_24420 617866a5178037e0cc11600993a5cc75 271 SUPERFAMILY SSF55781 76 270 1.18E-35 T 14-10-2018 LH59_24420 617866a5178037e0cc11600993a5cc75 271 Gene3D G3DSA:1.10.10.10 16 93 2.0E-11 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_24420 617866a5178037e0cc11600993a5cc75 271 Pfam PF09339 IclR helix-turn-helix domain 20 70 5.3E-9 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_24420 617866a5178037e0cc11600993a5cc75 271 SMART SM00346 18 108 8.9E-11 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_24420 617866a5178037e0cc11600993a5cc75 271 Pfam PF01614 Bacterial transcriptional regulator 137 265 1.7E-11 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal LH59_24340 e3fe0b484957c999869d65468e1ba733 391 Gene3D G3DSA:3.40.50.2300 142 352 3.3E-95 T 14-10-2018 LH59_24340 e3fe0b484957c999869d65468e1ba733 391 Pfam PF13458 Periplasmic binding protein 25 358 1.0E-73 T 14-10-2018 IPR028081 Leucine-binding protein domain LH59_24340 e3fe0b484957c999869d65468e1ba733 391 SUPERFAMILY SSF53822 25 375 5.57E-83 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_24340 e3fe0b484957c999869d65468e1ba733 391 Gene3D G3DSA:3.40.50.2300 26 350 3.3E-95 T 14-10-2018 LH59_01660 595e2af008736bbde07ef111ab8a85f0 220 Gene3D G3DSA:1.10.3720.10 12 220 1.5E-40 T 14-10-2018 IPR035906 MetI-like superfamily LH59_01660 595e2af008736bbde07ef111ab8a85f0 220 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 55 220 6.4E-15 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_01660 595e2af008736bbde07ef111ab8a85f0 220 SUPERFAMILY SSF161098 12 205 2.62E-37 T 14-10-2018 IPR035906 MetI-like superfamily LH59_22640 7628ee3f48261e4040d5b41d05c47f69 368 Gene3D G3DSA:2.60.40.1090 247 367 3.5E-5 T 14-10-2018 IPR036937 Fimbrial-type adhesion domain superfamily GO:0007155|GO:0009289 LH59_22640 7628ee3f48261e4040d5b41d05c47f69 368 SUPERFAMILY SSF49401 219 367 3.11E-6 T 14-10-2018 IPR008966 Adhesion domain superfamily LH59_15895 897dc47f68d2f3bc48bf01accba0f1ef 469 PRINTS PR01036 Tetracycline resistance protein TetB signature 24 48 9.7E-13 T 14-10-2018 LH59_15895 897dc47f68d2f3bc48bf01accba0f1ef 469 PRINTS PR01036 Tetracycline resistance protein TetB signature 407 426 9.7E-13 T 14-10-2018 LH59_15895 897dc47f68d2f3bc48bf01accba0f1ef 469 PRINTS PR01036 Tetracycline resistance protein TetB signature 145 169 9.7E-13 T 14-10-2018 LH59_15895 897dc47f68d2f3bc48bf01accba0f1ef 469 PRINTS PR01036 Tetracycline resistance protein TetB signature 115 135 9.7E-13 T 14-10-2018 LH59_15895 897dc47f68d2f3bc48bf01accba0f1ef 469 Gene3D G3DSA:1.20.1720.10 22 240 1.8E-47 T 14-10-2018 LH59_15895 897dc47f68d2f3bc48bf01accba0f1ef 469 Gene3D G3DSA:1.20.1250.20 264 468 1.9E-16 T 14-10-2018 LH59_15895 897dc47f68d2f3bc48bf01accba0f1ef 469 SUPERFAMILY SSF103473 9 463 1.44E-58 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_15895 897dc47f68d2f3bc48bf01accba0f1ef 469 Pfam PF07690 Major Facilitator Superfamily 25 416 4.8E-48 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_19795 a49d50cf72d71b41043fba219a8b0fa2 309 Pfam PF00482 Type II secretion system (T2SS), protein F 142 268 1.0E-13 T 14-10-2018 IPR018076 Type II secretion system F domain LH59_27355 dda5f8aae590ae1dbd96cd0fc3121dd3 383 SUPERFAMILY SSF53756 38 380 9.94E-11 T 14-10-2018 LH59_10205 8e26334b99ee8e6b1baddcb8edcb7994 244 SUPERFAMILY SSF55729 29 202 1.87E-37 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_10205 8e26334b99ee8e6b1baddcb8edcb7994 244 Pfam PF13302 Acetyltransferase (GNAT) domain 37 178 2.5E-15 T 14-10-2018 IPR000182 GNAT domain LH59_10205 8e26334b99ee8e6b1baddcb8edcb7994 244 Gene3D G3DSA:3.40.630.30 17 238 6.7E-64 T 14-10-2018 LH59_07695 fe9dd6f816079adebc06a735d9fcbcfc 262 Pfam PF01738 Dienelactone hydrolase family 36 262 4.0E-64 T 14-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 LH59_07695 fe9dd6f816079adebc06a735d9fcbcfc 262 Gene3D G3DSA:3.40.50.1820 21 261 1.2E-61 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_07695 fe9dd6f816079adebc06a735d9fcbcfc 262 SUPERFAMILY SSF53474 26 262 5.55E-47 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_01905 9f2b0a2a7417cef97640652d111de0b3 348 Pfam PF02653 Branched-chain amino acid transport system / permease component 33 324 9.6E-33 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_01905 9f2b0a2a7417cef97640652d111de0b3 348 TIGRFAM TIGR03408 urea_trans_UrtC: urea ABC transporter, permease protein UrtC 25 334 4.2E-124 T 14-10-2018 IPR017778 ABC transporter, urea, permease protein, UrtC LH59_14300 6939d172228b651c3371b1291043e1d1 312 Gene3D G3DSA:3.40.190.10 113 237 5.7E-96 T 14-10-2018 LH59_14300 6939d172228b651c3371b1291043e1d1 312 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 35 306 2.6E-66 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_14300 6939d172228b651c3371b1291043e1d1 312 PIRSF PIRSF017082 1 311 2.5E-72 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_14300 6939d172228b651c3371b1291043e1d1 312 SUPERFAMILY SSF53850 108 275 1.52E-10 T 14-10-2018 LH59_14300 6939d172228b651c3371b1291043e1d1 312 Gene3D G3DSA:3.40.190.150 16 302 5.7E-96 T 14-10-2018 LH59_03775 789cdca9ca46c799889f7c2d8b96ac9e 165 Pfam PF04073 Aminoacyl-tRNA editing domain 36 151 8.7E-26 T 14-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 LH59_03775 789cdca9ca46c799889f7c2d8b96ac9e 165 Gene3D G3DSA:3.90.960.10 9 164 7.5E-40 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 LH59_03775 789cdca9ca46c799889f7c2d8b96ac9e 165 SUPERFAMILY SSF55826 14 161 3.53E-32 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 LH59_03660 b1eaafc7036ccb13b0aaa67e63386b26 271 Gene3D G3DSA:3.20.20.370 1 266 3.8E-22 T 14-10-2018 LH59_03660 b1eaafc7036ccb13b0aaa67e63386b26 271 SUPERFAMILY SSF88713 2 264 2.67E-49 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 LH59_03660 b1eaafc7036ccb13b0aaa67e63386b26 271 Pfam PF04794 YdjC-like protein 4 256 3.6E-40 T 14-10-2018 IPR006879 Carbohydrate deacetylase YdjC-like LH59_22275 e827f4ce2305ea09e970a4b4e329a894 257 Gene3D G3DSA:3.40.50.300 5 251 7.8E-56 T 14-10-2018 LH59_22275 e827f4ce2305ea09e970a4b4e329a894 257 SUPERFAMILY SSF52540 4 247 2.22E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_22275 e827f4ce2305ea09e970a4b4e329a894 257 SMART SM00382 30 224 3.3E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_22275 e827f4ce2305ea09e970a4b4e329a894 257 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 226 246 4.8E-7 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal LH59_22275 e827f4ce2305ea09e970a4b4e329a894 257 Pfam PF00005 ABC transporter 22 176 4.7E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_02660 4aa57a5d6ded36ae3f25a1c36604ad35 338 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 57 331 2.5E-89 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_02660 4aa57a5d6ded36ae3f25a1c36604ad35 338 PIRSF PIRSF017082 1 337 7.8E-82 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_02660 4aa57a5d6ded36ae3f25a1c36604ad35 338 Gene3D G3DSA:3.40.190.10 136 263 1.3E-115 T 14-10-2018 LH59_02660 4aa57a5d6ded36ae3f25a1c36604ad35 338 Gene3D G3DSA:3.40.190.150 38 328 1.3E-115 T 14-10-2018 LH59_02660 4aa57a5d6ded36ae3f25a1c36604ad35 338 SUPERFAMILY SSF53850 123 298 1.45E-11 T 14-10-2018 LH59_02115 63a964f387ea8b348d00043c12653e74 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 318 3.3E-37 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_02115 63a964f387ea8b348d00043c12653e74 325 SUPERFAMILY SSF161098 90 304 1.36E-20 T 14-10-2018 IPR035906 MetI-like superfamily LH59_02115 63a964f387ea8b348d00043c12653e74 325 Gene3D G3DSA:1.10.3720.10 84 315 1.1E-26 T 14-10-2018 IPR035906 MetI-like superfamily LH59_14675 6197ac4276e64fa0ca4a6b964c807f34 490 Gene3D G3DSA:3.30.565.10 340 490 1.5E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_14675 6197ac4276e64fa0ca4a6b964c807f34 490 Gene3D G3DSA:1.10.287.130 260 335 1.6E-20 T 14-10-2018 LH59_14675 6197ac4276e64fa0ca4a6b964c807f34 490 Pfam PF00512 His Kinase A (phospho-acceptor) domain 268 335 1.2E-14 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_14675 6197ac4276e64fa0ca4a6b964c807f34 490 PRINTS PR00344 Bacterial sensor protein C-terminal signature 450 468 1.8E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_14675 6197ac4276e64fa0ca4a6b964c807f34 490 PRINTS PR00344 Bacterial sensor protein C-terminal signature 418 432 1.8E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_14675 6197ac4276e64fa0ca4a6b964c807f34 490 PRINTS PR00344 Bacterial sensor protein C-terminal signature 474 487 1.8E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 LH59_14675 6197ac4276e64fa0ca4a6b964c807f34 490 SUPERFAMILY SSF55874 325 488 3.14E-37 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_14675 6197ac4276e64fa0ca4a6b964c807f34 490 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 386 488 7.8E-16 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_14675 6197ac4276e64fa0ca4a6b964c807f34 490 SMART SM00387 381 490 2.2E-25 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_14675 6197ac4276e64fa0ca4a6b964c807f34 490 SUPERFAMILY SSF47384 252 335 6.28E-18 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 LH59_14675 6197ac4276e64fa0ca4a6b964c807f34 490 SMART SM00388 267 335 3.1E-18 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 LH59_07800 b61a45c3a441c7eaa490ad02b3eaf1e8 265 Hamap MF_01527_B GTP cyclohydrolase FolE2 [folE2]. 11 265 35.342 T 14-10-2018 IPR022838 GTP cyclohydrolase FolE2 GO:0003934|GO:0035998 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 LH59_07800 b61a45c3a441c7eaa490ad02b3eaf1e8 265 Gene3D G3DSA:3.10.270.10 9 264 6.0E-92 T 14-10-2018 LH59_07800 b61a45c3a441c7eaa490ad02b3eaf1e8 265 Pfam PF02649 Type I GTP cyclohydrolase folE2 11 261 2.1E-88 T 14-10-2018 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 LH59_23760 2b734febeebfd278572fe396ee22b203 421 Gene3D G3DSA:3.90.1530.10 133 240 3.9E-10 T 14-10-2018 LH59_23760 2b734febeebfd278572fe396ee22b203 421 Pfam PF08857 Putative ParB-like nuclease 56 283 2.7E-51 T 14-10-2018 IPR014956 Putative ParB-like nuclease LH59_23760 2b734febeebfd278572fe396ee22b203 421 SUPERFAMILY SSF110849 52 290 3.87E-47 T 14-10-2018 IPR036086 ParB/Sulfiredoxin superfamily LH59_11895 0572c946adb74fb2199c0d939aeb5a28 299 Pfam PF00892 EamA-like transporter family 153 283 2.5E-19 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_11895 0572c946adb74fb2199c0d939aeb5a28 299 Pfam PF00892 EamA-like transporter family 13 140 9.7E-11 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_11895 0572c946adb74fb2199c0d939aeb5a28 299 SUPERFAMILY SSF103481 188 286 2.22E-14 T 14-10-2018 LH59_11895 0572c946adb74fb2199c0d939aeb5a28 299 SUPERFAMILY SSF103481 40 140 1.83E-13 T 14-10-2018 LH59_05810 4586e3c92e7914b522370bfd124f1707 239 Gene3D G3DSA:1.10.10.10 160 237 7.9E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_05810 4586e3c92e7914b522370bfd124f1707 239 Gene3D G3DSA:2.60.120.10 8 158 7.9E-26 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_05810 4586e3c92e7914b522370bfd124f1707 239 SUPERFAMILY SSF46785 160 232 4.84E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_05810 4586e3c92e7914b522370bfd124f1707 239 SMART SM00419 176 224 1.1E-8 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 LH59_05810 4586e3c92e7914b522370bfd124f1707 239 Pfam PF13545 Crp-like helix-turn-helix domain 163 231 5.0E-16 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 LH59_05810 4586e3c92e7914b522370bfd124f1707 239 Pfam PF00027 Cyclic nucleotide-binding domain 44 130 1.2E-11 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain LH59_05810 4586e3c92e7914b522370bfd124f1707 239 SUPERFAMILY SSF51206 13 156 2.23E-20 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like LH59_05810 4586e3c92e7914b522370bfd124f1707 239 SMART SM00100 20 146 8.6E-10 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain LH59_24305 d2e3cfb1b8a349942e41974de31d989e 315 PIRSF PIRSF035875 6 307 1.7E-71 T 14-10-2018 IPR017039 Virulence factor BrkB LH59_24305 d2e3cfb1b8a349942e41974de31d989e 315 Pfam PF03631 Virulence factor BrkB 29 285 9.2E-54 T 14-10-2018 IPR017039 Virulence factor BrkB LH59_24305 d2e3cfb1b8a349942e41974de31d989e 315 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 24 282 3.4E-22 T 14-10-2018 IPR017039 Virulence factor BrkB LH59_10380 7d527080453a773333bde086bc856949 220 Pfam PF07791 Protein of unknown function (DUF1629) 21 142 1.2E-47 T 14-10-2018 IPR012433 Protein of unknown function DUF1629 LH59_05250 62be670c9bce49b9bcdc23bd65e1f9f0 184 Pfam PF07514 Putative helicase 62 151 1.9E-27 T 14-10-2018 IPR011119 Uncharacterised domain, helicase/relaxase, putative LH59_05250 62be670c9bce49b9bcdc23bd65e1f9f0 184 Gene3D G3DSA:1.10.3210.40 50 161 6.3E-14 T 14-10-2018 LH59_05250 62be670c9bce49b9bcdc23bd65e1f9f0 184 SUPERFAMILY SSF56935 1 46 1.83E-5 T 14-10-2018 LH59_05250 62be670c9bce49b9bcdc23bd65e1f9f0 184 Gene3D G3DSA:2.170.130.10 1 29 3.5E-5 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily LH59_26240 673ba236eebdf3363dc2053b0c4bd3c6 302 PRINTS PR00111 Alpha/beta hydrolase fold signature 127 140 3.0E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_26240 673ba236eebdf3363dc2053b0c4bd3c6 302 PRINTS PR00111 Alpha/beta hydrolase fold signature 241 255 3.0E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_26240 673ba236eebdf3363dc2053b0c4bd3c6 302 PRINTS PR00111 Alpha/beta hydrolase fold signature 80 95 3.0E-5 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_26240 673ba236eebdf3363dc2053b0c4bd3c6 302 Pfam PF00561 alpha/beta hydrolase fold 54 284 7.4E-23 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_26240 673ba236eebdf3363dc2053b0c4bd3c6 302 Gene3D G3DSA:3.40.50.1820 24 298 8.2E-79 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_26240 673ba236eebdf3363dc2053b0c4bd3c6 302 SUPERFAMILY SSF53474 38 297 7.3E-46 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_03230 019f49e7cef7ebdfb47b7357c638b53b 186 Pfam PF02325 YGGT family 110 176 3.3E-15 T 14-10-2018 IPR003425 CCB3/YggT GO:0016020 LH59_03230 019f49e7cef7ebdfb47b7357c638b53b 186 Pfam PF02325 YGGT family 12 80 2.0E-13 T 14-10-2018 IPR003425 CCB3/YggT GO:0016020 LH59_25210 17134b5c1b5f19a85a8782aa521522a1 340 SUPERFAMILY SSF56529 74 320 5.63E-54 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 LH59_25210 17134b5c1b5f19a85a8782aa521522a1 340 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 84 320 1.9E-35 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 LH59_25210 17134b5c1b5f19a85a8782aa521522a1 340 Gene3D G3DSA:3.90.850.10 1 323 1.6E-124 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 LH59_14080 52be6d5a1747922895814bc9a363d792 201 SUPERFAMILY SSF55729 20 189 2.02E-44 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_14080 52be6d5a1747922895814bc9a363d792 201 SMART SM01006 29 76 1.5E-12 T 14-10-2018 IPR019432 Siderophore biosynthesis protein, conserved domain LH59_14080 52be6d5a1747922895814bc9a363d792 201 Pfam PF13523 Acetyltransferase (GNAT) domain 32 175 1.0E-45 T 14-10-2018 LH59_14080 52be6d5a1747922895814bc9a363d792 201 Gene3D G3DSA:3.40.630.30 11 199 2.9E-49 T 14-10-2018 LH59_07240 a97a2516a63a5815dceeadbf936aeb9f 391 Gene3D G3DSA:1.20.1250.20 4 378 3.8E-46 T 14-10-2018 LH59_07240 a97a2516a63a5815dceeadbf936aeb9f 391 SUPERFAMILY SSF103473 4 381 1.57E-55 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_07240 a97a2516a63a5815dceeadbf936aeb9f 391 Pfam PF07690 Major Facilitator Superfamily 10 319 5.3E-34 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_22280 5df451385358503e9e523d84f8623761 236 SMART SM00382 29 213 3.7E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_22280 5df451385358503e9e523d84f8623761 236 Pfam PF00005 ABC transporter 20 164 8.6E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_22280 5df451385358503e9e523d84f8623761 236 Gene3D G3DSA:3.40.50.300 2 236 6.8E-59 T 14-10-2018 LH59_22280 5df451385358503e9e523d84f8623761 236 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_22280 5df451385358503e9e523d84f8623761 236 SUPERFAMILY SSF52540 4 232 4.19E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_19835 7f4b028934c23e1df1e5c3312394d216 58 Pfam PF04964 Flp/Fap pilin component 8 52 8.8E-14 T 14-10-2018 IPR007047 Flp/Fap pilin component LH59_03510 c5cc6fbea62fe7d49a879283fa16634b 390 Gene3D G3DSA:3.40.50.2300 133 358 1.5E-30 T 14-10-2018 LH59_03510 c5cc6fbea62fe7d49a879283fa16634b 390 Pfam PF04392 ABC transporter substrate binding protein 140 386 2.5E-15 T 14-10-2018 IPR007487 ABC transporter, substrate-binding protein LH59_03510 c5cc6fbea62fe7d49a879283fa16634b 390 Gene3D G3DSA:3.40.50.2300 198 383 1.5E-30 T 14-10-2018 LH59_02205 056c8cfc34ede05f1cfdc90c38ef734b 159 SUPERFAMILY SSF69118 4 145 1.33E-42 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 LH59_02205 056c8cfc34ede05f1cfdc90c38ef734b 159 Gene3D G3DSA:1.20.1290.10 1 148 5.5E-43 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 LH59_02205 056c8cfc34ede05f1cfdc90c38ef734b 159 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 37 78 2.6E-12 T 14-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 LH59_02205 056c8cfc34ede05f1cfdc90c38ef734b 159 Pfam PF02627 Carboxymuconolactone decarboxylase family 12 94 5.2E-17 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 LH59_16590 e05dbbc442eb9e31f96b7e09edd1961a 222 Pfam PF00072 Response regulator receiver domain 3 112 2.3E-22 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_16590 e05dbbc442eb9e31f96b7e09edd1961a 222 Gene3D G3DSA:3.40.50.2300 1 121 2.5E-34 T 14-10-2018 LH59_16590 e05dbbc442eb9e31f96b7e09edd1961a 222 SUPERFAMILY SSF46894 125 216 3.68E-23 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 LH59_16590 e05dbbc442eb9e31f96b7e09edd1961a 222 SUPERFAMILY SSF52172 2 118 3.7E-33 T 14-10-2018 IPR011006 CheY-like superfamily LH59_16590 e05dbbc442eb9e31f96b7e09edd1961a 222 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 216 1.9E-19 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_16590 e05dbbc442eb9e31f96b7e09edd1961a 222 SMART SM00862 145 216 1.0E-22 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 LH59_16590 e05dbbc442eb9e31f96b7e09edd1961a 222 Gene3D G3DSA:1.10.10.10 122 221 1.5E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_16590 e05dbbc442eb9e31f96b7e09edd1961a 222 SMART SM00448 1 112 2.4E-32 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 LH59_24050 faa8e5f7deea5ec455da1674667c9df6 396 Gene3D G3DSA:1.20.1250.20 2 390 8.3E-23 T 14-10-2018 LH59_24050 faa8e5f7deea5ec455da1674667c9df6 396 SUPERFAMILY SSF103473 4 394 3.14E-28 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_24050 faa8e5f7deea5ec455da1674667c9df6 396 Pfam PF07690 Major Facilitator Superfamily 14 353 1.6E-16 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_01570 7fd3c1c3203d9249df03a685f6c0fdc0 159 Pfam PF03928 Haem-degrading 7 137 1.2E-25 T 14-10-2018 IPR005624 Haem-degrading LH59_01570 7fd3c1c3203d9249df03a685f6c0fdc0 159 Gene3D G3DSA:3.30.450.150 1 143 1.2E-38 T 14-10-2018 IPR038084 GlcG-like domain superfamily LH59_01570 7fd3c1c3203d9249df03a685f6c0fdc0 159 SUPERFAMILY SSF143744 2 140 1.96E-33 T 14-10-2018 IPR038084 GlcG-like domain superfamily LH59_22045 4c49e175ffda9cca0d7a39d58effd4f3 346 Gene3D G3DSA:3.40.190.10 37 335 4.2E-125 T 14-10-2018 LH59_22045 4c49e175ffda9cca0d7a39d58effd4f3 346 SUPERFAMILY SSF53850 33 282 2.06E-44 T 14-10-2018 LH59_22045 4c49e175ffda9cca0d7a39d58effd4f3 346 Gene3D G3DSA:3.40.190.10 116 226 4.2E-125 T 14-10-2018 LH59_22045 4c49e175ffda9cca0d7a39d58effd4f3 346 Pfam PF13379 NMT1-like family 33 271 2.9E-28 T 14-10-2018 LH59_22045 4c49e175ffda9cca0d7a39d58effd4f3 346 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 3 19 0.001 T 14-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal LH59_07545 0514dca44f4e66c3d5e82d70ad4b49b1 209 Gene3D G3DSA:3.50.30.50 1 209 2.4E-66 T 14-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 LH59_07545 0514dca44f4e66c3d5e82d70ad4b49b1 209 SUPERFAMILY SSF102198 2 206 1.31E-56 T 14-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 LH59_07545 0514dca44f4e66c3d5e82d70ad4b49b1 209 Pfam PF04199 Putative cyclase 6 151 1.4E-17 T 14-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 LH59_07545 0514dca44f4e66c3d5e82d70ad4b49b1 209 Hamap MF_01969 Kynurenine formamidase [kynB]. 3 208 44.022 T 14-10-2018 IPR017484 Kynurenine formamidase, bacteria GO:0004328|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 LH59_07545 0514dca44f4e66c3d5e82d70ad4b49b1 209 TIGRFAM TIGR03035 trp_arylform: arylformamidase 3 208 6.4E-99 T 14-10-2018 IPR017484 Kynurenine formamidase, bacteria GO:0004328|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 LH59_22095 ffae793c4d1083bde31d142f3676dc2a 399 Gene3D G3DSA:1.20.1250.20 3 199 1.8E-25 T 14-10-2018 LH59_22095 ffae793c4d1083bde31d142f3676dc2a 399 SUPERFAMILY SSF103473 7 390 8.89E-60 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_22095 ffae793c4d1083bde31d142f3676dc2a 399 Pfam PF07690 Major Facilitator Superfamily 18 342 2.6E-33 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_22095 ffae793c4d1083bde31d142f3676dc2a 399 Gene3D G3DSA:1.20.1250.20 202 392 2.4E-22 T 14-10-2018 LH59_06300 9f711d1efbd328f6d6983d18f97a8574 345 Pfam PF02653 Branched-chain amino acid transport system / permease component 11 330 1.7E-21 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_00890 194892d8261d4aa356a9ce64fc61ee38 150 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 7 148 23.11 T 14-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 LH59_00890 194892d8261d4aa356a9ce64fc61ee38 150 Gene3D G3DSA:1.10.1200.120 7 150 4.4E-39 T 14-10-2018 IPR036019 Gated mechanosensitive channel LH59_00890 194892d8261d4aa356a9ce64fc61ee38 150 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 7 149 7.2E-36 T 14-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 LH59_00890 194892d8261d4aa356a9ce64fc61ee38 150 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 7 147 1.9E-41 T 14-10-2018 IPR037673 Large-conductance mechanosensitive channel/anditomin synthesis protein L LH59_00890 194892d8261d4aa356a9ce64fc61ee38 150 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 10 24 3.0E-8 T 14-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 LH59_00890 194892d8261d4aa356a9ce64fc61ee38 150 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 100 108 3.0E-8 T 14-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 LH59_00890 194892d8261d4aa356a9ce64fc61ee38 150 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 109 118 3.0E-8 T 14-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 LH59_00890 194892d8261d4aa356a9ce64fc61ee38 150 SUPERFAMILY SSF81330 17 143 6.8E-32 T 14-10-2018 IPR036019 Gated mechanosensitive channel LH59_02595 6a8af506d675fa9f479c10c3df1a6f79 481 ProSitePatterns PS00571 Amidases signature. 161 192 - T 14-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 LH59_02595 6a8af506d675fa9f479c10c3df1a6f79 481 Gene3D G3DSA:3.90.1300.10 12 474 2.3E-121 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_02595 6a8af506d675fa9f479c10c3df1a6f79 481 SUPERFAMILY SSF75304 12 473 5.49E-113 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_02595 6a8af506d675fa9f479c10c3df1a6f79 481 Pfam PF01425 Amidase 30 463 2.2E-95 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_18185 b6cfb9ebf1be6ed6568ae047db352e2e 146 Pfam PF07849 Protein of unknown function (DUF1641) 97 134 1.3E-6 T 14-10-2018 IPR012440 Protein of unknown function DUF1641 LH59_00245 a134506d21f83d64e8c9653843714c2e 343 Gene3D G3DSA:3.40.50.2300 144 328 4.4E-68 T 14-10-2018 LH59_00245 a134506d21f83d64e8c9653843714c2e 343 SUPERFAMILY SSF53822 54 240 2.35E-6 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_00245 a134506d21f83d64e8c9653843714c2e 343 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 57 284 4.5E-39 T 14-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 LH59_00245 a134506d21f83d64e8c9653843714c2e 343 Gene3D G3DSA:3.40.50.2300 56 301 4.4E-68 T 14-10-2018 LH59_09655 1514cc23c6b12e19720d75efc78f6b7c 83 Pfam PF04380 Membrane fusogenic activity 4 75 2.3E-25 T 14-10-2018 IPR007475 Membrane fusogenic activity LH59_07170 ada0b6623cd8249627e5ae3950e45d22 137 Gene3D G3DSA:1.10.10.690 1 135 2.5E-34 T 14-10-2018 IPR027405 YidB-like LH59_07170 ada0b6623cd8249627e5ae3950e45d22 137 Pfam PF06078 Bacterial protein of unknown function (DUF937) 2 110 5.7E-10 T 14-10-2018 IPR009282 Protein of unknown function DUF937 LH59_07170 ada0b6623cd8249627e5ae3950e45d22 137 SUPERFAMILY SSF140804 11 128 4.32E-31 T 14-10-2018 IPR027405 YidB-like LH59_14730 05680fe342f17a4982173668ffdfa809 195 SUPERFAMILY SSF46689 1 66 8.21E-14 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_14730 05680fe342f17a4982173668ffdfa809 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 45 1.8E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_14730 05680fe342f17a4982173668ffdfa809 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 1 14 1.8E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_14730 05680fe342f17a4982173668ffdfa809 195 SUPERFAMILY SSF48498 69 185 9.78E-20 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily LH59_14730 05680fe342f17a4982173668ffdfa809 195 Gene3D G3DSA:1.10.10.60 1 45 3.7E-16 T 14-10-2018 LH59_14730 05680fe342f17a4982173668ffdfa809 195 Pfam PF09209 Domain of unknown function (DUF1956) 74 187 9.4E-23 T 14-10-2018 IPR015292 Transcription regulator YbiH, C-terminal LH59_14730 05680fe342f17a4982173668ffdfa809 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 1 47 6.0E-11 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_14730 05680fe342f17a4982173668ffdfa809 195 Gene3D G3DSA:1.10.357.10 46 193 3.7E-30 T 14-10-2018 LH59_24960 711205068ed76a00a4eedbade1314fba 522 Pfam PF12792 CSS motif domain associated with EAL 40 235 2.3E-23 T 14-10-2018 IPR024744 Putative cyclic diguanylate phosphodiesterase, CSS motif-containing domain LH59_24960 711205068ed76a00a4eedbade1314fba 522 SUPERFAMILY SSF141868 266 509 3.27E-76 T 14-10-2018 IPR035919 EAL domain superfamily LH59_24960 711205068ed76a00a4eedbade1314fba 522 Pfam PF00563 EAL domain 266 497 4.1E-64 T 14-10-2018 IPR001633 EAL domain LH59_24960 711205068ed76a00a4eedbade1314fba 522 Gene3D G3DSA:3.20.20.450 259 514 4.8E-80 T 14-10-2018 IPR035919 EAL domain superfamily LH59_24960 711205068ed76a00a4eedbade1314fba 522 SMART SM00052 260 502 2.0E-95 T 14-10-2018 IPR001633 EAL domain LH59_02650 3e03f87b984a18f264a8e792a77e17bb 367 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 175 361 7.5E-22 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_02650 3e03f87b984a18f264a8e792a77e17bb 367 Gene3D G3DSA:1.10.3720.10 149 366 5.3E-50 T 14-10-2018 IPR035906 MetI-like superfamily LH59_02650 3e03f87b984a18f264a8e792a77e17bb 367 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 157 253 2.1E-18 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 LH59_02650 3e03f87b984a18f264a8e792a77e17bb 367 SUPERFAMILY SSF161098 156 347 1.96E-41 T 14-10-2018 IPR035906 MetI-like superfamily LH59_06410 838bf22e887311e9b225168288bb726f 437 SUPERFAMILY SSF103473 9 431 4.45E-64 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_06410 838bf22e887311e9b225168288bb726f 437 Pfam PF00083 Sugar (and other) transporter 12 435 8.4E-36 T 14-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 LH59_06410 838bf22e887311e9b225168288bb726f 437 Gene3D G3DSA:1.20.1250.20 8 437 4.6E-66 T 14-10-2018 LH59_06410 838bf22e887311e9b225168288bb726f 437 ProSitePatterns PS00217 Sugar transport proteins signature 2. 125 150 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 LH59_06410 838bf22e887311e9b225168288bb726f 437 ProSitePatterns PS00216 Sugar transport proteins signature 1. 302 318 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 LH59_16405 24216f6f5e323ab69de45dbb08ad4d0f 313 Pfam PF05368 NmrA-like family 12 237 8.9E-17 T 14-10-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 LH59_16405 24216f6f5e323ab69de45dbb08ad4d0f 313 SUPERFAMILY SSF51735 9 257 4.04E-23 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_16405 24216f6f5e323ab69de45dbb08ad4d0f 313 Gene3D G3DSA:3.90.25.10 157 259 9.6E-31 T 14-10-2018 LH59_16405 24216f6f5e323ab69de45dbb08ad4d0f 313 Gene3D G3DSA:3.40.50.720 9 217 9.6E-31 T 14-10-2018 LH59_01520 9b167d0d4d58be3a1d6a234e4eadbf29 134 Pfam PF10990 Protein of unknown function (DUF2809) 33 111 2.6E-16 T 14-10-2018 IPR021257 Protein of unknown function DUF2809 LH59_20155 446408958f5a66e66107cab6bf352428 208 Gene3D G3DSA:2.60.120.10 45 188 6.8E-57 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_20155 446408958f5a66e66107cab6bf352428 208 SUPERFAMILY SSF51182 10 195 3.34E-52 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_20155 446408958f5a66e66107cab6bf352428 208 Pfam PF05995 Cysteine dioxygenase type I 74 158 9.5E-8 T 14-10-2018 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 LH59_07770 a7467e05fda9b2acbb4cc3ee49867780 336 Pfam PF01757 Acyltransferase family 9 327 3.8E-32 T 14-10-2018 IPR002656 Acyltransferase 3 GO:0016747 LH59_12575 01916302357c305851dc45f964c23aec 256 Pfam PF09297 NADH pyrophosphatase zinc ribbon domain 92 119 1.3E-9 T 14-10-2018 IPR015376 Zinc ribbon, NADH pyrophosphatase GO:0016787|GO:0046872 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381|MetaCyc: PWY-7761 LH59_12575 01916302357c305851dc45f964c23aec 256 ProSitePatterns PS00893 Nudix box signature. 158 179 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 LH59_12575 01916302357c305851dc45f964c23aec 256 Gene3D G3DSA:3.90.79.10 125 250 2.2E-36 T 14-10-2018 LH59_12575 01916302357c305851dc45f964c23aec 256 Pfam PF00293 NUDIX domain 129 230 3.0E-18 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 LH59_12575 01916302357c305851dc45f964c23aec 256 SUPERFAMILY SSF55811 77 231 3.54E-42 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 LH59_12575 01916302357c305851dc45f964c23aec 256 Gene3D G3DSA:3.90.79.20 2 124 2.9E-21 T 14-10-2018 LH59_12575 01916302357c305851dc45f964c23aec 256 Pfam PF09296 NADH pyrophosphatase-like rudimentary NUDIX domain 10 90 9.6E-6 T 14-10-2018 IPR015375 NADH pyrophosphatase-like, N-terminal GO:0016787 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381|MetaCyc: PWY-7761 LH59_22525 9fc5525b91c2fb84dfc6d87dff699679 105 Gene3D G3DSA:1.10.1660.10 15 104 8.9E-23 T 14-10-2018 LH59_22525 9fc5525b91c2fb84dfc6d87dff699679 105 Pfam PF13591 MerR HTH family regulatory protein 19 100 1.4E-12 T 14-10-2018 LH59_00275 08c6893b9f11a7dac15728c5fa30c09e 165 SUPERFAMILY SSF52309 1 161 1.34E-47 T 14-10-2018 LH59_00275 08c6893b9f11a7dac15728c5fa30c09e 165 Pfam PF05014 Nucleoside 2-deoxyribosyltransferase 4 143 4.4E-46 T 14-10-2018 IPR007710 Nucleoside 2-deoxyribosyltransferase Reactome: R-HSA-74259 LH59_00275 08c6893b9f11a7dac15728c5fa30c09e 165 Gene3D G3DSA:3.40.50.450 1 165 1.8E-56 T 14-10-2018 LH59_26970 ca1a469435d3cb9d0a8af58f7435b95d 115 Gene3D G3DSA:1.20.120.30 1 115 2.4E-10 T 14-10-2018 LH59_26970 ca1a469435d3cb9d0a8af58f7435b95d 115 Pfam PF13682 Chemoreceptor zinc-binding domain 10 75 5.7E-12 T 14-10-2018 IPR025991 Chemoreceptor zinc-binding domain LH59_26640 ab43c865cb0d644bb4298cd0cf928aa0 111 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 4 92 6.9E-25 T 14-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 LH59_26640 ab43c865cb0d644bb4298cd0cf928aa0 111 Gene3D G3DSA:3.30.160.100 1 106 4.9E-33 T 14-10-2018 IPR036567 Ribosome hibernation promotion factor-like LH59_26640 ab43c865cb0d644bb4298cd0cf928aa0 111 SUPERFAMILY SSF69754 2 101 5.1E-33 T 14-10-2018 IPR036567 Ribosome hibernation promotion factor-like LH59_26640 ab43c865cb0d644bb4298cd0cf928aa0 111 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 98 1.1E-30 T 14-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 LH59_19685 ae22091ae9d9742b150370cc282959d8 491 ProSitePatterns PS00455 Putative AMP-binding domain signature. 135 146 - T 14-10-2018 IPR020845 AMP-binding, conserved site LH59_19685 ae22091ae9d9742b150370cc282959d8 491 Gene3D G3DSA:3.30.300.310 385 487 2.3E-29 T 14-10-2018 LH59_19685 ae22091ae9d9742b150370cc282959d8 491 Pfam PF00501 AMP-binding enzyme 11 389 6.3E-66 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 LH59_19685 ae22091ae9d9742b150370cc282959d8 491 Gene3D G3DSA:3.40.50.12780 2 381 3.8E-93 T 14-10-2018 LH59_19685 ae22091ae9d9742b150370cc282959d8 491 Pfam PF13193 AMP-binding enzyme C-terminal domain 398 473 3.0E-15 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain LH59_19685 ae22091ae9d9742b150370cc282959d8 491 SUPERFAMILY SSF56801 6 486 7.85E-118 T 14-10-2018 LH59_15885 7fae70dc4f787cb99084955d16170730 237 Pfam PF13618 Gluconate 2-dehydrogenase subunit 3 56 209 1.8E-37 T 14-10-2018 IPR027056 Gluconate 2-dehydrogenase subunit 3 KEGG: 00030+1.1.99.3|MetaCyc: PWY-7165 LH59_07720 f3e5b076eefdc75bdd7c4fa311049998 284 SUPERFAMILY SSF103481 37 136 1.57E-12 T 14-10-2018 LH59_07720 f3e5b076eefdc75bdd7c4fa311049998 284 Pfam PF00892 EamA-like transporter family 142 273 1.4E-7 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_07720 f3e5b076eefdc75bdd7c4fa311049998 284 Pfam PF00892 EamA-like transporter family 3 132 1.9E-7 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_07720 f3e5b076eefdc75bdd7c4fa311049998 284 SUPERFAMILY SSF103481 198 279 6.8E-9 T 14-10-2018 LH59_08670 55358bf09b13749d08ea3f36ae48aa16 509 ProSitePatterns PS00571 Amidases signature. 168 199 - T 14-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 LH59_08670 55358bf09b13749d08ea3f36ae48aa16 509 SUPERFAMILY SSF75304 8 498 6.28E-102 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_08670 55358bf09b13749d08ea3f36ae48aa16 509 Pfam PF01425 Amidase 33 489 5.8E-73 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_08670 55358bf09b13749d08ea3f36ae48aa16 509 Gene3D G3DSA:3.90.1300.10 7 508 4.3E-122 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_16460 a10b4d51525c82c1504e7a90fe376c93 483 Gene3D G3DSA:1.10.4160.10 3 460 2.7E-103 T 14-10-2018 IPR038271 Purine-cytosine permease superfamily LH59_16460 a10b4d51525c82c1504e7a90fe376c93 483 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 17 443 1.0E-73 T 14-10-2018 IPR001248 Purine-cytosine permease GO:0016020|GO:0022857|GO:0055085 LH59_00300 02c77ed55ecab593618c21357090b9de 306 Pfam PF01062 Bestrophin, RFP-TM, chloride channel 1 284 8.6E-62 T 14-10-2018 IPR021134 Bestrophin/UPF0187 Reactome: R-HSA-2672351 LH59_01870 9a41df73a749627036d897b64316b9dd 338 SUPERFAMILY SSF52402 41 260 1.46E-54 T 14-10-2018 LH59_01870 9a41df73a749627036d897b64316b9dd 338 Gene3D G3DSA:3.40.50.620 25 281 3.8E-47 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LH59_01870 9a41df73a749627036d897b64316b9dd 338 Hamap MF_01850 tRNA-cytidine(32) 2-sulfurtransferase [ttcA]. 33 295 55.673 T 14-10-2018 IPR012089 tRNA-cytidine(32) 2-sulfurtransferase GO:0008033 LH59_01870 9a41df73a749627036d897b64316b9dd 338 Pfam PF01171 PP-loop family 66 228 4.2E-14 T 14-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 LH59_26915 a0ddcc163fb4d4bc8def7876a6c950a9 287 SUPERFAMILY SSF56281 9 286 2.57E-48 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like LH59_26915 a0ddcc163fb4d4bc8def7876a6c950a9 287 Pfam PF00753 Metallo-beta-lactamase superfamily 14 205 6.6E-20 T 14-10-2018 IPR001279 Metallo-beta-lactamase LH59_26915 a0ddcc163fb4d4bc8def7876a6c950a9 287 Gene3D G3DSA:3.60.15.10 1 287 9.3E-111 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like LH59_26915 a0ddcc163fb4d4bc8def7876a6c950a9 287 SMART SM00849 14 205 1.3E-21 T 14-10-2018 IPR001279 Metallo-beta-lactamase LH59_11115 c22d0ea3375fd4f3af61ef1003d712bd 268 Gene3D G3DSA:2.60.120.200 32 257 4.6E-16 T 14-10-2018 LH59_11115 c22d0ea3375fd4f3af61ef1003d712bd 268 SUPERFAMILY SSF49899 32 260 3.56E-16 T 14-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily LH59_11115 c22d0ea3375fd4f3af61ef1003d712bd 268 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 92 254 9.7E-7 T 14-10-2018 LH59_13945 7d44a85bf2525cbde9ae76117493dafc 259 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 253 1.4E-24 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_13945 7d44a85bf2525cbde9ae76117493dafc 259 Gene3D G3DSA:1.10.3720.10 57 253 1.2E-27 T 14-10-2018 IPR035906 MetI-like superfamily LH59_13945 7d44a85bf2525cbde9ae76117493dafc 259 SUPERFAMILY SSF161098 57 243 2.35E-33 T 14-10-2018 IPR035906 MetI-like superfamily LH59_09850 2a2e9d56491d597ebf874c11839f6123 176 Pfam PF02566 OsmC-like protein 63 166 3.7E-18 T 14-10-2018 IPR003718 OsmC/Ohr family LH59_09850 2a2e9d56491d597ebf874c11839f6123 176 SUPERFAMILY SSF82784 21 169 1.44E-32 T 14-10-2018 IPR036102 OsmC/Ohr superfamily LH59_09850 2a2e9d56491d597ebf874c11839f6123 176 Gene3D G3DSA:3.30.300.20 17 174 1.5E-31 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta LH59_19640 d32667ea03280296eeac508e7f6b0f8d 288 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 275 7.7E-40 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_19190 fa0a16370004d2354ec47c1639b3bdaf 179 Gene3D G3DSA:3.10.180.10 4 145 6.6E-32 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_19190 fa0a16370004d2354ec47c1639b3bdaf 179 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 131 5.5E-31 T 14-10-2018 LH59_19190 fa0a16370004d2354ec47c1639b3bdaf 179 SUPERFAMILY SSF54593 8 146 1.06E-17 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_21485 36a3ffddc123fc02217b0505a20149b2 182 Gene3D G3DSA:1.20.120.520 9 178 2.8E-44 T 14-10-2018 LH59_21485 36a3ffddc123fc02217b0505a20149b2 182 Pfam PF01814 Hemerythrin HHE cation binding domain 19 157 3.8E-19 T 14-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 LH59_22750 bdea40f3ad317700998ccaabb2fd6af1 122 Pfam PF05973 Phage derived protein Gp49-like (DUF891) 17 109 2.2E-17 T 14-10-2018 IPR009241 Toxin HigB-like LH59_27490 48ffbafdc2adb8c12a11bd11cfd8c2ea 288 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 7 278 5.4E-15 T 14-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase LH59_27490 48ffbafdc2adb8c12a11bd11cfd8c2ea 288 Gene3D G3DSA:3.60.10.10 3 288 1.2E-41 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily LH59_27490 48ffbafdc2adb8c12a11bd11cfd8c2ea 288 SUPERFAMILY SSF56219 4 285 9.29E-41 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily LH59_14240 2b6ef21eb0269944c8d764f8df82aab2 395 SUPERFAMILY SSF82171 50 258 4.19E-9 T 14-10-2018 LH59_14240 2b6ef21eb0269944c8d764f8df82aab2 395 Gene3D G3DSA:2.120.10.30 32 268 9.4E-10 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like LH59_07525 ce99cd2010c10829ac81b5e1e3694e41 468 TIGRFAM TIGR00797 matE: MATE efflux family protein 24 413 1.6E-70 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 LH59_07525 ce99cd2010c10829ac81b5e1e3694e41 468 PIRSF PIRSF006603 12 467 9.2E-53 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 LH59_07525 ce99cd2010c10829ac81b5e1e3694e41 468 Pfam PF01554 MatE 249 410 3.5E-19 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 LH59_07525 ce99cd2010c10829ac81b5e1e3694e41 468 Pfam PF01554 MatE 24 184 3.3E-23 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 LH59_07155 90c39df524f6a24b3b987a5b3131fd43 280 Pfam PF04305 Protein of unknown function (DUF455) 58 272 2.4E-93 T 14-10-2018 IPR007402 Protein of unknown function DUF455 LH59_07155 90c39df524f6a24b3b987a5b3131fd43 280 PIRSF PIRSF012318 19 279 9.1E-97 T 14-10-2018 IPR011197 Uncharacterised conserved protein UCP012318 LH59_07155 90c39df524f6a24b3b987a5b3131fd43 280 SUPERFAMILY SSF47240 87 254 5.68E-19 T 14-10-2018 IPR009078 Ferritin-like superfamily LH59_19805 a562caa8da3a64fb6f1eabe7c097827c 446 Gene3D G3DSA:3.40.50.300 151 420 7.8E-36 T 14-10-2018 LH59_19805 a562caa8da3a64fb6f1eabe7c097827c 446 SUPERFAMILY SSF52172 29 140 5.71E-8 T 14-10-2018 IPR011006 CheY-like superfamily LH59_19805 a562caa8da3a64fb6f1eabe7c097827c 446 SUPERFAMILY SSF52540 154 418 1.3E-20 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_19805 a562caa8da3a64fb6f1eabe7c097827c 446 Gene3D G3DSA:3.40.50.2300 16 145 6.2E-13 T 14-10-2018 LH59_04735 9dc2065c5d246a6ff875fd830f865ac3 476 Pfam PF02321 Outer membrane efflux protein 69 250 8.0E-18 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 LH59_04735 9dc2065c5d246a6ff875fd830f865ac3 476 Pfam PF02321 Outer membrane efflux protein 283 459 1.8E-20 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 LH59_04735 9dc2065c5d246a6ff875fd830f865ac3 476 Gene3D G3DSA:1.20.1600.10 60 460 1.3E-104 T 14-10-2018 LH59_04735 9dc2065c5d246a6ff875fd830f865ac3 476 Gene3D G3DSA:2.20.200.10 106 350 1.3E-104 T 14-10-2018 LH59_04735 9dc2065c5d246a6ff875fd830f865ac3 476 SUPERFAMILY SSF56954 7 461 1.44E-86 T 14-10-2018 LH59_04735 9dc2065c5d246a6ff875fd830f865ac3 476 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 14 460 2.1E-83 T 14-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 LH59_12275 db57600f630318cb69fea530631521b3 282 Pfam PF12710 haloacid dehalogenase-like hydrolase 8 210 5.4E-8 T 14-10-2018 LH59_12275 db57600f630318cb69fea530631521b3 282 SUPERFAMILY SSF56784 5 222 2.51E-12 T 14-10-2018 IPR036412 HAD-like superfamily LH59_12275 db57600f630318cb69fea530631521b3 282 Gene3D G3DSA:3.40.50.1000 6 236 9.3E-15 T 14-10-2018 IPR023214 HAD superfamily LH59_05120 00a026a04a6f69a44833ef8c8d037580 111 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 11 107 1.0E-21 T 14-10-2018 IPR008407 Branched-chain amino acid transport, AzlD LH59_27805 f4e2c784a1c81f624c6be0e03da3d015 254 Gene3D G3DSA:2.60.120.330 34 216 7.7E-55 T 14-10-2018 IPR027443 Isopenicillin N synthase-like LH59_27805 f4e2c784a1c81f624c6be0e03da3d015 254 Pfam PF05118 Aspartyl/Asparaginyl beta-hydroxylase 54 210 1.1E-47 T 14-10-2018 IPR007803 Aspartyl/asparaginy/proline hydroxylase GO:0018193 LH59_27805 f4e2c784a1c81f624c6be0e03da3d015 254 SUPERFAMILY SSF51197 61 232 1.98E-21 T 14-10-2018 LH59_18165 cb32e8dc1335c6d79b7c0d518fb501f0 403 Gene3D G3DSA:3.40.50.12030 184 403 1.7E-87 T 14-10-2018 LH59_18165 cb32e8dc1335c6d79b7c0d518fb501f0 403 Hamap MF_00677 UPF0261 protein . 5 403 49.733 T 14-10-2018 IPR008322 Uncharacterised protein family UPF0261 LH59_18165 cb32e8dc1335c6d79b7c0d518fb501f0 403 Gene3D G3DSA:3.40.50.12020 1 176 1.6E-55 T 14-10-2018 LH59_18165 cb32e8dc1335c6d79b7c0d518fb501f0 403 PIRSF PIRSF033271 4 403 1.4E-178 T 14-10-2018 IPR008322 Uncharacterised protein family UPF0261 LH59_18165 cb32e8dc1335c6d79b7c0d518fb501f0 403 Pfam PF06792 Uncharacterised protein family (UPF0261) 7 400 7.0E-156 T 14-10-2018 IPR008322 Uncharacterised protein family UPF0261 LH59_17110 46367981905e9d38582908665e1d6c9c 217 Gene3D G3DSA:1.10.357.10 5 204 4.7E-57 T 14-10-2018 LH59_17110 46367981905e9d38582908665e1d6c9c 217 SUPERFAMILY SSF48498 95 203 3.6E-15 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily LH59_17110 46367981905e9d38582908665e1d6c9c 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 41 3.9E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_17110 46367981905e9d38582908665e1d6c9c 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 49 72 3.9E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_17110 46367981905e9d38582908665e1d6c9c 217 ProSitePatterns PS01081 TetR-type HTH domain signature. 40 71 - T 14-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site LH59_17110 46367981905e9d38582908665e1d6c9c 217 SUPERFAMILY SSF46689 22 100 7.77E-18 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_17110 46367981905e9d38582908665e1d6c9c 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 31 74 1.1E-16 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_03545 e912100933b509a53bf6c2262776ea51 311 PIRSF PIRSF019423 2 310 1.0E-145 T 14-10-2018 IPR011213 Nicotinic acid mononucleotide biosynthesis protein LH59_03545 e912100933b509a53bf6c2262776ea51 311 Gene3D G3DSA:1.10.10.10 221 298 3.1E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_03545 e912100933b509a53bf6c2262776ea51 311 SUPERFAMILY SSF46785 228 299 2.31E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_03545 e912100933b509a53bf6c2262776ea51 311 SUPERFAMILY SSF55811 15 125 7.91E-8 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 LH59_14190 c2110f460d235f80a08d1eb0ef34184b 314 SMART SM00859 5 106 1.9E-11 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 LH59_14190 c2110f460d235f80a08d1eb0ef34184b 314 Gene3D G3DSA:3.30.360.10 115 293 7.5E-50 T 14-10-2018 LH59_14190 c2110f460d235f80a08d1eb0ef34184b 314 TIGRFAM TIGR01851 argC_other: N-acetyl-gamma-glutamyl-phosphate reductase 4 306 6.4E-121 T 14-10-2018 IPR010136 N-acetyl-gamma-glutamyl-phosphate reductase, type 2 GO:0003942|GO:0005737|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 LH59_14190 c2110f460d235f80a08d1eb0ef34184b 314 Gene3D G3DSA:3.40.50.720 13 306 7.5E-50 T 14-10-2018 LH59_14190 c2110f460d235f80a08d1eb0ef34184b 314 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 45 102 2.7E-10 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 LH59_14190 c2110f460d235f80a08d1eb0ef34184b 314 Hamap MF_01110 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 2 308 51.637 T 14-10-2018 IPR010136 N-acetyl-gamma-glutamyl-phosphate reductase, type 2 GO:0003942|GO:0005737|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 LH59_14190 c2110f460d235f80a08d1eb0ef34184b 314 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 112 128 - T 14-10-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 LH59_14190 c2110f460d235f80a08d1eb0ef34184b 314 SUPERFAMILY SSF55347 117 289 1.7E-36 T 14-10-2018 LH59_14190 c2110f460d235f80a08d1eb0ef34184b 314 SUPERFAMILY SSF51735 6 139 1.15E-29 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_06590 05fcfe80ee1f6b4114a7c860a47620c8 428 SUPERFAMILY SSF103473 25 420 4.19E-29 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_06590 05fcfe80ee1f6b4114a7c860a47620c8 428 Pfam PF07690 Major Facilitator Superfamily 31 331 5.7E-10 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_06590 05fcfe80ee1f6b4114a7c860a47620c8 428 Gene3D G3DSA:1.20.1250.20 24 413 3.5E-21 T 14-10-2018 LH59_22955 670ac9f5a9ffe01aac6dc734d408b641 174 Pfam PF02417 Chromate transporter 8 169 5.0E-32 T 14-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 LH59_22955 670ac9f5a9ffe01aac6dc734d408b641 174 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 18 32 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 LH59_01985 5a22f7fc1ffd674731e69b1f27e62865 518 Pfam PF06742 Protein of unknown function (DUF1214) 394 502 5.4E-35 T 14-10-2018 IPR010621 Domain of unknown function DUF1214 LH59_01985 5a22f7fc1ffd674731e69b1f27e62865 518 Pfam PF06863 Protein of unknown function (DUF1254) 96 226 3.8E-36 T 14-10-2018 IPR010679 Domain of unknown function DUF1254 LH59_01985 5a22f7fc1ffd674731e69b1f27e62865 518 Gene3D G3DSA:2.60.120.600 367 518 1.3E-41 T 14-10-2018 IPR037049 Domain of unknown function DUF1214, C-terminal domain superfamily LH59_01985 5a22f7fc1ffd674731e69b1f27e62865 518 SUPERFAMILY SSF160935 46 516 1.83E-111 T 14-10-2018 LH59_02445 63259df1a0ee4736841a2c1273a086c4 158 Pfam PF04214 Protein of unknown function, DUF 61 128 2.9E-29 T 14-10-2018 IPR007332 Protein of unknown function DUF411 LH59_10595 224307b9d8e95dd1ad3e37b10856b2bc 106 SUPERFAMILY SSF47413 37 92 1.8E-5 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 LH59_12560 bff6f76139d2251e2779804379b71818 433 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 11 422 4.3E-79 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit LH59_12560 bff6f76139d2251e2779804379b71818 433 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 21 428 1.7E-123 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 LH59_12560 bff6f76139d2251e2779804379b71818 433 PIRSF PIRSF006066 5 433 2.1E-88 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 LH59_11785 356c798c1f470e6ffce1c0b4adc9bc03 391 Gene3D G3DSA:3.90.226.10 3 389 3.9E-122 T 14-10-2018 LH59_11785 356c798c1f470e6ffce1c0b4adc9bc03 391 Pfam PF16113 Enoyl-CoA hydratase/isomerase 19 371 8.9E-114 T 14-10-2018 IPR032259 Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type GO:0003860 Reactome: R-HSA-70895 LH59_11785 356c798c1f470e6ffce1c0b4adc9bc03 391 SUPERFAMILY SSF52096 18 357 6.52E-62 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily LH59_01345 e3e4e5f201b44264aa4fe6a76f58491e 369 Gene3D G3DSA:3.40.50.300 16 188 2.5E-24 T 14-10-2018 LH59_01345 e3e4e5f201b44264aa4fe6a76f58491e 369 SUPERFAMILY SSF52540 24 160 7.55E-20 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_01345 e3e4e5f201b44264aa4fe6a76f58491e 369 Pfam PF01926 50S ribosome-binding GTPase 31 151 5.7E-12 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 LH59_01345 e3e4e5f201b44264aa4fe6a76f58491e 369 Pfam PF05128 Domain of unknown function (DUF697) 221 366 8.3E-8 T 14-10-2018 IPR021147 Protein of unknown function DUF697 LH59_22715 dcfddefa1e6f827ad0b14e282d3dbcd2 337 Pfam PF00296 Luciferase-like monooxygenase 19 297 1.5E-58 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LH59_22715 dcfddefa1e6f827ad0b14e282d3dbcd2 337 Gene3D G3DSA:3.20.20.30 1 327 3.6E-88 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 LH59_22715 dcfddefa1e6f827ad0b14e282d3dbcd2 337 SUPERFAMILY SSF51679 1 326 1.18E-80 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 LH59_20600 eff5748f73ee00c66ea877d878bfc31e 374 Pfam PF06804 NlpB/DapX lipoprotein 40 372 2.3E-46 T 14-10-2018 IPR010653 NlpB/DapX lipoprotein LH59_20600 eff5748f73ee00c66ea877d878bfc31e 374 Gene3D G3DSA:3.30.310.170 256 374 4.7E-15 T 14-10-2018 LH59_10400 0dd44858f257dde5b3b4b25f479c303e 166 Pfam PF03918 Cytochrome C biogenesis protein 9 146 6.6E-45 T 14-10-2018 IPR005616 CcmH/CycL/Ccl2/NrfF family LH59_10400 0dd44858f257dde5b3b4b25f479c303e 166 Gene3D G3DSA:1.10.8.640 25 105 9.4E-29 T 14-10-2018 IPR038297 CcmH/CycL/Ccl2/NrfF domain superfamily LH59_16465 e8b1fa39530433c61c1c6d674624f296 459 Pfam PF03729 Short repeat of unknown function (DUF308) 81 147 5.3E-5 T 14-10-2018 IPR005325 Protein of unknown function DUF308, membrane LH59_15280 ca3db7bd9e3cc2ebf897f0bb78314ffa 317 SUPERFAMILY SSF103481 42 142 5.89E-6 T 14-10-2018 LH59_15280 ca3db7bd9e3cc2ebf897f0bb78314ffa 317 Pfam PF00892 EamA-like transporter family 3 112 3.3E-11 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_26410 acd45703982c1b6466855233e2ce6507 310 SUPERFAMILY SSF53335 37 268 1.56E-26 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_26410 acd45703982c1b6466855233e2ce6507 310 Gene3D G3DSA:3.40.50.150 44 242 4.6E-26 T 14-10-2018 LH59_26410 acd45703982c1b6466855233e2ce6507 310 Pfam PF08241 Methyltransferase domain 58 167 1.7E-15 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 LH59_19225 9733fb04ac132de145bd766c11378d86 96 Gene3D G3DSA:3.40.640.10 25 94 3.2E-9 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_19225 9733fb04ac132de145bd766c11378d86 96 SUPERFAMILY SSF53383 25 69 1.8E-8 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_19225 9733fb04ac132de145bd766c11378d86 96 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 25 70 9.9E-16 T 14-10-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 LH59_20840 c0b8a9b2eafefe051393460a002f209e 313 PIRSF PIRSF018266 2 313 2.7E-81 T 14-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component LH59_20840 c0b8a9b2eafefe051393460a002f209e 313 Gene3D G3DSA:2.60.120.1440 99 227 1.2E-12 T 14-10-2018 LH59_20840 c0b8a9b2eafefe051393460a002f209e 313 Pfam PF04773 FecR protein 106 198 2.8E-17 T 14-10-2018 IPR006860 FecR protein LH59_20840 c0b8a9b2eafefe051393460a002f209e 313 Pfam PF16220 Domain of unknown function (DUF4880) 9 51 2.7E-9 T 14-10-2018 IPR032623 FecR, N-terminal LH59_04795 46c9e397bb8d308304c9391a237536ac 307 SUPERFAMILY SSF53613 2 305 1.39E-79 T 14-10-2018 IPR029056 Ribokinase-like LH59_04795 46c9e397bb8d308304c9391a237536ac 307 Pfam PF00294 pfkB family carbohydrate kinase 5 296 1.3E-56 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB LH59_04795 46c9e397bb8d308304c9391a237536ac 307 Gene3D G3DSA:3.40.1190.20 4 307 3.5E-84 T 14-10-2018 IPR029056 Ribokinase-like LH59_26285 e4d3c52df5acaa56608292029ae0ba0f 376 SUPERFAMILY SSF56059 118 214 4.24E-6 T 14-10-2018 LH59_26285 e4d3c52df5acaa56608292029ae0ba0f 376 Pfam PF11379 Protein of unknown function (DUF3182) 12 365 2.6E-129 T 14-10-2018 IPR021519 Protein of unknown function DUF3182 LH59_20475 996a6cbedca3e2f2433a76989c472ddc 60 Pfam PF13318 Protein of unknown function (DUF4089) 9 58 6.4E-10 T 14-10-2018 IPR025148 Protein of unknown function DUF4089 LH59_01140 24c2b570989d89351d0e2b827d7408dc 74 Pfam PF11174 Protein of unknown function (DUF2970) 15 70 1.4E-24 T 14-10-2018 IPR021344 Protein of unknown function DUF2970 LH59_28230 bc2ff0708cf73b887f037acc612e989e 308 SUPERFAMILY SSF53686 5 308 4.98E-76 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme LH59_28230 bc2ff0708cf73b887f037acc612e989e 308 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 33 46 - T 14-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 LH59_28230 bc2ff0708cf73b887f037acc612e989e 308 Gene3D G3DSA:3.40.50.1100 8 308 2.6E-85 T 14-10-2018 LH59_28230 bc2ff0708cf73b887f037acc612e989e 308 Gene3D G3DSA:3.40.50.1100 43 152 2.6E-85 T 14-10-2018 LH59_28230 bc2ff0708cf73b887f037acc612e989e 308 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 303 2.4E-58 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme LH59_28230 bc2ff0708cf73b887f037acc612e989e 308 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 31 49 - T 14-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 LH59_07185 a384e1170b33f3bbbed9d12e1528bdb8 226 ProDom PD022759 ALGINATE BIOSYNTHESIS ALGF PRECURSOR SIGNAL PERIPLASMIC TRANSFERASE O-ACETYLTRANSFERASE 30 210 0.006 T 14-10-2018 IPR035422 Alginate O-acetyl transferase AlgF GO:0042121 LH59_07185 a384e1170b33f3bbbed9d12e1528bdb8 226 Pfam PF11182 Alginate O-acetyl transferase AlgF 14 180 2.7E-15 T 14-10-2018 IPR035422 Alginate O-acetyl transferase AlgF GO:0042121 LH59_11880 f37f87d2ca1dc7697636558bdd2a4a4a 91 SUPERFAMILY SSF82649 5 61 5.23E-5 T 14-10-2018 LH59_11880 f37f87d2ca1dc7697636558bdd2a4a4a 91 Gene3D G3DSA:3.30.390.50 1 88 1.7E-22 T 14-10-2018 LH59_11880 f37f87d2ca1dc7697636558bdd2a4a4a 91 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 7 63 9.9E-6 T 14-10-2018 IPR019491 Lipoate protein ligase, C-terminal KEGG: 00785+6.3.1.20 LH59_18295 adb3c130f8f3c54084034ef9ac782fc6 215 Pfam PF00043 Glutathione S-transferase, C-terminal domain 120 196 4.3E-9 T 14-10-2018 IPR004046 Glutathione S-transferase, C-terminal LH59_18295 adb3c130f8f3c54084034ef9ac782fc6 215 Pfam PF02798 Glutathione S-transferase, N-terminal domain 2 74 1.2E-15 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 LH59_18295 adb3c130f8f3c54084034ef9ac782fc6 215 SUPERFAMILY SSF47616 80 202 1.95E-26 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily LH59_18295 adb3c130f8f3c54084034ef9ac782fc6 215 Gene3D G3DSA:3.40.30.10 1 83 2.3E-31 T 14-10-2018 LH59_18295 adb3c130f8f3c54084034ef9ac782fc6 215 SUPERFAMILY SSF52833 1 83 8.08E-23 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_18295 adb3c130f8f3c54084034ef9ac782fc6 215 Gene3D G3DSA:1.20.1050.10 84 202 9.1E-40 T 14-10-2018 LH59_07840 f69a23a1b24fb21917ba13239886e918 325 PIRSF PIRSF026166 1 325 2.6E-133 T 14-10-2018 IPR016833 Putative sodium bile acid cotransporter LH59_07840 f69a23a1b24fb21917ba13239886e918 325 Pfam PF13593 SBF-like CPA transporter family (DUF4137) 10 317 9.7E-96 T 14-10-2018 IPR016833 Putative sodium bile acid cotransporter LH59_07840 f69a23a1b24fb21917ba13239886e918 325 Gene3D G3DSA:1.20.1530.20 1 320 4.5E-34 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily LH59_01495 91329fc767b84942f206b757a67c3e0c 331 Pfam PF05229 Spore Coat Protein U domain 17 145 3.2E-14 T 14-10-2018 IPR007893 Spore coat protein U LH59_01495 91329fc767b84942f206b757a67c3e0c 331 Pfam PF05229 Spore Coat Protein U domain 197 328 1.6E-36 T 14-10-2018 IPR007893 Spore coat protein U LH59_01495 91329fc767b84942f206b757a67c3e0c 331 SMART SM00972 269 328 8.3E-25 T 14-10-2018 IPR007893 Spore coat protein U LH59_01495 91329fc767b84942f206b757a67c3e0c 331 SMART SM00972 95 181 0.044 T 14-10-2018 IPR007893 Spore coat protein U LH59_20345 5583060af2c7a467afd673ba5dcb1080 287 Pfam PF02673 Bacitracin resistance protein BacA 11 278 4.7E-82 T 14-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 LH59_20345 5583060af2c7a467afd673ba5dcb1080 287 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 6 284 17.822 T 14-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 LH59_15725 5fa73d0418582c6e71e38ccbb9e7c555 357 SUPERFAMILY SSF144052 20 333 1.44E-15 T 14-10-2018 LH59_09450 796512d5d3d8768a6820e60f58b2b5fb 364 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 42 320 4.4E-43 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 LH59_09450 796512d5d3d8768a6820e60f58b2b5fb 364 Gene3D G3DSA:3.40.190.10 153 323 9.9E-106 T 14-10-2018 LH59_09450 796512d5d3d8768a6820e60f58b2b5fb 364 PIRSF PIRSF039026 1 356 4.0E-103 T 14-10-2018 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like LH59_09450 796512d5d3d8768a6820e60f58b2b5fb 364 Gene3D G3DSA:3.40.190.170 34 337 9.9E-106 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily LH59_09450 796512d5d3d8768a6820e60f58b2b5fb 364 SUPERFAMILY SSF53850 165 302 1.83E-7 T 14-10-2018 LH59_01260 f5f5d0819a2c52c94c36e36adc23d688 323 SUPERFAMILY SSF81345 2 319 1.44E-68 T 14-10-2018 IPR037294 ABC transporter, BtuC-like LH59_01260 f5f5d0819a2c52c94c36e36adc23d688 323 Gene3D G3DSA:1.10.3470.10 1 322 7.1E-84 T 14-10-2018 IPR037294 ABC transporter, BtuC-like LH59_01260 f5f5d0819a2c52c94c36e36adc23d688 323 Pfam PF01032 FecCD transport family 9 319 7.9E-81 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 LH59_13305 9d5a65a0ad48eb6c01b1c07b4fa07575 275 Gene3D G3DSA:1.10.12.10 220 275 9.1E-23 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal LH59_13305 9d5a65a0ad48eb6c01b1c07b4fa07575 275 SUPERFAMILY SSF52096 22 274 2.49E-75 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily LH59_13305 9d5a65a0ad48eb6c01b1c07b4fa07575 275 Pfam PF00378 Enoyl-CoA hydratase/isomerase 29 275 4.0E-48 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 LH59_13305 9d5a65a0ad48eb6c01b1c07b4fa07575 275 Gene3D G3DSA:3.90.226.10 22 218 3.6E-62 T 14-10-2018 LH59_07445 b2389ce6c4e6845e31ce2d112a80de69 126 PRINTS PR00061 Ribosomal protein L19 signature 38 67 3.8E-32 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_07445 b2389ce6c4e6845e31ce2d112a80de69 126 PRINTS PR00061 Ribosomal protein L19 signature 92 117 3.8E-32 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_07445 b2389ce6c4e6845e31ce2d112a80de69 126 PRINTS PR00061 Ribosomal protein L19 signature 8 37 3.8E-32 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_07445 b2389ce6c4e6845e31ce2d112a80de69 126 PIRSF PIRSF002191 1 126 2.1E-50 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_07445 b2389ce6c4e6845e31ce2d112a80de69 126 SUPERFAMILY SSF50104 2 118 4.81E-43 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily LH59_07445 b2389ce6c4e6845e31ce2d112a80de69 126 Pfam PF01245 Ribosomal protein L19 9 117 2.9E-45 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_07445 b2389ce6c4e6845e31ce2d112a80de69 126 Gene3D G3DSA:2.30.30.790 4 122 1.0E-16 T 14-10-2018 IPR038657 Ribosomal protein L19 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_07445 b2389ce6c4e6845e31ce2d112a80de69 126 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 1 117 2.0E-46 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_07445 b2389ce6c4e6845e31ce2d112a80de69 126 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 1 118 29.697 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_07445 b2389ce6c4e6845e31ce2d112a80de69 126 ProSitePatterns PS01015 Ribosomal protein L19 signature. 90 105 - T 14-10-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 LH59_18205 8d6d9b16fe8b59f4f0d87cafd6cf3b01 383 SUPERFAMILY SSF53474 78 222 6.41E-9 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_18205 8d6d9b16fe8b59f4f0d87cafd6cf3b01 383 Gene3D G3DSA:3.40.50.1820 52 365 6.9E-61 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_27675 17c5c449957ad208538df06f6fc4388b 448 Pfam PF01578 Cytochrome C assembly protein 186 443 9.1E-45 T 14-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 LH59_27675 17c5c449957ad208538df06f6fc4388b 448 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 159 446 2.2E-73 T 14-10-2018 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 LH59_17020 3bfaab4835f79337821b101815e16084 323 SUPERFAMILY SSF81345 5 316 4.18E-59 T 14-10-2018 IPR037294 ABC transporter, BtuC-like LH59_17020 3bfaab4835f79337821b101815e16084 323 Pfam PF01032 FecCD transport family 13 316 4.0E-62 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 LH59_17020 3bfaab4835f79337821b101815e16084 323 Gene3D G3DSA:1.10.3470.10 4 322 1.6E-60 T 14-10-2018 IPR037294 ABC transporter, BtuC-like LH59_20680 86fd711cf5d6e6a5641bd54f662a902b 123 Gene3D G3DSA:2.40.50.140 11 123 5.6E-32 T 14-10-2018 LH59_20680 86fd711cf5d6e6a5641bd54f662a902b 123 TIGRFAM TIGR02222 chap_CsaA: export-related chaperone protein CsaA 17 122 9.6E-43 T 14-10-2018 IPR008231 Probable chaperone CsaA LH59_20680 86fd711cf5d6e6a5641bd54f662a902b 123 SUPERFAMILY SSF50249 14 122 3.14E-30 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_20680 86fd711cf5d6e6a5641bd54f662a902b 123 Pfam PF01588 Putative tRNA binding domain 25 120 2.2E-11 T 14-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 LH59_28170 53c161dd80ad5c647f5ec6d5db72d270 464 SUPERFAMILY SSF81340 19 443 1.7E-92 T 14-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 LH59_28170 53c161dd80ad5c647f5ec6d5db72d270 464 Gene3D G3DSA:1.10.3080.10 25 447 3.7E-93 T 14-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 LH59_28170 53c161dd80ad5c647f5ec6d5db72d270 464 PRINTS PR00762 Chloride channel signature 178 197 5.5E-26 T 14-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 LH59_28170 53c161dd80ad5c647f5ec6d5db72d270 464 PRINTS PR00762 Chloride channel signature 396 415 5.5E-26 T 14-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 LH59_28170 53c161dd80ad5c647f5ec6d5db72d270 464 PRINTS PR00762 Chloride channel signature 378 394 5.5E-26 T 14-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 LH59_28170 53c161dd80ad5c647f5ec6d5db72d270 464 PRINTS PR00762 Chloride channel signature 342 362 5.5E-26 T 14-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 LH59_28170 53c161dd80ad5c647f5ec6d5db72d270 464 PRINTS PR00762 Chloride channel signature 127 146 5.5E-26 T 14-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 LH59_28170 53c161dd80ad5c647f5ec6d5db72d270 464 Pfam PF00654 Voltage gated chloride channel 85 428 3.5E-82 T 14-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 LH59_07655 017097d7d91e9f451608288ad6c842a1 130 SUPERFAMILY SSF55331 2 125 4.82E-21 T 14-10-2018 IPR014347 Tautomerase/MIF superfamily LH59_07655 017097d7d91e9f451608288ad6c842a1 130 Gene3D G3DSA:3.30.429.10 1 61 1.2E-10 T 14-10-2018 IPR014347 Tautomerase/MIF superfamily LH59_07655 017097d7d91e9f451608288ad6c842a1 130 Gene3D G3DSA:3.30.429.10 67 129 4.8E-10 T 14-10-2018 IPR014347 Tautomerase/MIF superfamily LH59_04545 af05da942e925add555ac4718a94fa7b 277 Gene3D G3DSA:3.20.20.60 1 276 3.0E-83 T 14-10-2018 LH59_04545 af05da942e925add555ac4718a94fa7b 277 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 7 214 6.4E-35 T 14-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 LH59_04545 af05da942e925add555ac4718a94fa7b 277 PIRSF PIRSF015582 1 277 1.8E-83 T 14-10-2018 IPR011206 Citrate lyase beta subunit-like LH59_04545 af05da942e925add555ac4718a94fa7b 277 SUPERFAMILY SSF51621 3 226 1.54E-61 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 LH59_25760 2975f5ed6481e03704937756f271ea0b 255 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 14 224 3.8E-32 T 14-10-2018 IPR008775 Phytanoyl-CoA dioxygenase LH59_25760 2975f5ed6481e03704937756f271ea0b 255 SUPERFAMILY SSF51197 3 244 5.04E-58 T 14-10-2018 LH59_25760 2975f5ed6481e03704937756f271ea0b 255 Gene3D G3DSA:2.60.120.620 1 255 1.7E-52 T 14-10-2018 LH59_06390 08b67c391c5a5f64474b9fb66eb3e3cb 117 Gene3D G3DSA:3.30.1330.40 1 117 5.5E-39 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 LH59_06390 08b67c391c5a5f64474b9fb66eb3e3cb 117 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 92 110 - T 14-10-2018 IPR019897 RidA, conserved site Reactome: R-HSA-8849175 LH59_06390 08b67c391c5a5f64474b9fb66eb3e3cb 117 Pfam PF01042 Endoribonuclease L-PSP 6 115 1.5E-24 T 14-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 LH59_06390 08b67c391c5a5f64474b9fb66eb3e3cb 117 SUPERFAMILY SSF55298 11 116 1.01E-28 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 LH59_22470 9669e07a356ddeaa25b033b36cef0405 179 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 20 153 7.5E-18 T 14-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like LH59_22470 9669e07a356ddeaa25b033b36cef0405 179 SUPERFAMILY SSF55961 3 175 1.6E-44 T 14-10-2018 LH59_22470 9669e07a356ddeaa25b033b36cef0405 179 Gene3D G3DSA:3.30.530.20 4 178 4.1E-51 T 14-10-2018 IPR023393 START-like domain superfamily LH59_02555 ba34782088b021c53547aea74da6ca1a 288 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 55 273 2.1E-19 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF LH59_02555 ba34782088b021c53547aea74da6ca1a 288 Gene3D G3DSA:3.40.190.10 44 150 8.9E-14 T 14-10-2018 LH59_02555 ba34782088b021c53547aea74da6ca1a 288 SUPERFAMILY SSF53850 55 274 1.55E-26 T 14-10-2018 LH59_02555 ba34782088b021c53547aea74da6ca1a 288 Gene3D G3DSA:3.40.190.10 151 240 3.2E-15 T 14-10-2018 LH59_02670 4a34f6ee580784506dd4353d7f609f8c 120 SUPERFAMILY SSF54593 10 119 4.26E-18 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_02670 4a34f6ee580784506dd4353d7f609f8c 120 Gene3D G3DSA:3.10.180.10 1 120 5.9E-26 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_04775 6b5b1234607ebec074b06a21c59aaf75 378 SUPERFAMILY SSF56322 34 376 2.75E-103 T 14-10-2018 IPR005801 ADC synthase GO:0009058 LH59_04775 6b5b1234607ebec074b06a21c59aaf75 378 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 82 376 1.4E-107 T 14-10-2018 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543 LH59_04775 6b5b1234607ebec074b06a21c59aaf75 378 PRINTS PR00095 Anthranilate synthase component I signature 313 327 6.0E-15 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 LH59_04775 6b5b1234607ebec074b06a21c59aaf75 378 PRINTS PR00095 Anthranilate synthase component I signature 328 342 6.0E-15 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 LH59_04775 6b5b1234607ebec074b06a21c59aaf75 378 PRINTS PR00095 Anthranilate synthase component I signature 220 233 6.0E-15 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 LH59_04775 6b5b1234607ebec074b06a21c59aaf75 378 PRINTS PR00095 Anthranilate synthase component I signature 234 247 6.0E-15 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 LH59_04775 6b5b1234607ebec074b06a21c59aaf75 378 Gene3D G3DSA:3.60.120.10 84 378 3.8E-112 T 14-10-2018 IPR005801 ADC synthase GO:0009058 LH59_04775 6b5b1234607ebec074b06a21c59aaf75 378 Pfam PF00425 chorismate binding enzyme 119 372 1.7E-85 T 14-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal LH59_20110 0a2ad79706cb2b16e4570a230fe9534b 343 Pfam PF03812 2-keto-3-deoxygluconate permease 14 317 4.6E-106 T 14-10-2018 IPR004684 2-keto-3-deoxygluconate permease GO:0008643|GO:0015649|GO:0016021|GO:0046411 LH59_20110 0a2ad79706cb2b16e4570a230fe9534b 343 ProDom PD024513 PERMEASE 2-KETO-3-DEOXYGLUCONATE MEMBRANE TRANSMEMBRANE SUGAR KDG SYMPORT INNER 2-KETO-3-DEOXY-D-GLUCONATE SYSTEM 34 317 1.0E-105 T 14-10-2018 IPR004684 2-keto-3-deoxygluconate permease GO:0008643|GO:0015649|GO:0016021|GO:0046411 LH59_02715 18522048bdbced1feed6d66589ee1389 132 Pfam PF01817 Chorismate mutase type II 37 118 7.1E-14 T 14-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 LH59_02715 18522048bdbced1feed6d66589ee1389 132 Gene3D G3DSA:1.20.59.10 27 128 1.1E-24 T 14-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 LH59_02715 18522048bdbced1feed6d66589ee1389 132 PIRSF PIRSF029775 21 127 3.1E-32 T 14-10-2018 IPR008241 Salicylate biosynthesis protein PchB GO:0004106|GO:0009697|GO:0016835 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6406|MetaCyc: PWY-6627|MetaCyc: PWY-7626 LH59_02715 18522048bdbced1feed6d66589ee1389 132 SUPERFAMILY SSF48600 28 120 2.62E-18 T 14-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 LH59_02715 18522048bdbced1feed6d66589ee1389 132 SMART SM00830 37 120 4.5E-17 T 14-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 LH59_22325 b0ec0ae29867b20a753134972a2f36f6 173 Gene3D G3DSA:3.40.50.7700 1 173 1.1E-67 T 14-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 LH59_22325 b0ec0ae29867b20a753134972a2f36f6 173 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 15 164 1.8E-58 T 14-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 LH59_22325 b0ec0ae29867b20a753134972a2f36f6 173 SUPERFAMILY SSF52255 14 168 1.57E-59 T 14-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 LH59_22325 b0ec0ae29867b20a753134972a2f36f6 173 Pfam PF00731 AIR carboxylase 15 162 2.5E-57 T 14-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 LH59_22325 b0ec0ae29867b20a753134972a2f36f6 173 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 15 168 29.86 T 14-10-2018 IPR033747 Class I PurE LH59_22325 b0ec0ae29867b20a753134972a2f36f6 173 SMART SM01001 13 164 1.6E-87 T 14-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 LH59_22325 b0ec0ae29867b20a753134972a2f36f6 173 PIRSF PIRSF001338 10 170 2.9E-61 T 14-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 LH59_20845 865242df763d43fbe990f8e676470907 164 Pfam PF04542 Sigma-70 region 2 10 75 6.8E-12 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 LH59_20845 865242df763d43fbe990f8e676470907 164 SUPERFAMILY SSF88659 87 158 9.38E-15 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like LH59_20845 865242df763d43fbe990f8e676470907 164 SUPERFAMILY SSF88946 7 93 2.9E-15 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 LH59_20845 865242df763d43fbe990f8e676470907 164 Pfam PF08281 Sigma-70, region 4 107 158 1.5E-16 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 LH59_20845 865242df763d43fbe990f8e676470907 164 Gene3D G3DSA:1.10.10.10 82 162 2.1E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_20845 865242df763d43fbe990f8e676470907 164 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 158 2.5E-22 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 LH59_20845 865242df763d43fbe990f8e676470907 164 Gene3D G3DSA:1.10.1740.10 4 72 1.5E-8 T 14-10-2018 LH59_11415 d5222b60e11850a75981e7a9c4f1a4f5 253 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 173 248 4.7E-17 T 14-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain LH59_11415 d5222b60e11850a75981e7a9c4f1a4f5 253 Pfam PF00460 Flagella basal body rod protein 5 35 8.8E-6 T 14-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 LH59_11415 d5222b60e11850a75981e7a9c4f1a4f5 253 SUPERFAMILY SSF117143 78 211 5.89E-13 T 14-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like LH59_11415 d5222b60e11850a75981e7a9c4f1a4f5 253 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 122 3.0E-30 T 14-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G LH59_11415 d5222b60e11850a75981e7a9c4f1a4f5 253 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 14-10-2018 IPR019776 Flagellar basal body rod protein, conserved site LH59_10330 b62d704e1d91944c49a2656af82617d4 222 Gene3D G3DSA:3.50.30.100 7 198 3.0E-55 T 14-10-2018 LH59_10330 b62d704e1d91944c49a2656af82617d4 222 SUPERFAMILY SSF89562 26 185 1.7E-45 T 14-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily LH59_10330 b62d704e1d91944c49a2656af82617d4 222 Pfam PF03737 Aldolase/RraA 29 174 4.8E-46 T 14-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein LH59_00260 a045247ad935bc850d0c37f64929f682 203 SUPERFAMILY SSF51735 1 202 5.61E-38 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_00260 a045247ad935bc850d0c37f64929f682 203 Pfam PF13460 NAD(P)H-binding 7 190 3.7E-28 T 14-10-2018 IPR016040 NAD(P)-binding domain LH59_00260 a045247ad935bc850d0c37f64929f682 203 Gene3D G3DSA:3.40.50.720 1 203 2.6E-53 T 14-10-2018 LH59_07175 e2e2823cea91271da5d4022e871d35a5 329 Gene3D G3DSA:3.20.20.80 20 328 4.8E-15 T 14-10-2018 LH59_07175 e2e2823cea91271da5d4022e871d35a5 329 Pfam PF14488 Domain of unknown function (DUF4434) 36 201 9.5E-29 T 14-10-2018 IPR027849 Protein of unknown function DUF4434 LH59_09695 37109b78d2bb4caa305fc52fdbcd4e11 143 Gene3D G3DSA:1.10.1660.10 13 87 9.7E-22 T 14-10-2018 LH59_09695 37109b78d2bb4caa305fc52fdbcd4e11 143 SUPERFAMILY SSF46955 17 119 2.29E-19 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily LH59_09695 37109b78d2bb4caa305fc52fdbcd4e11 143 Pfam PF13411 MerR HTH family regulatory protein 19 85 6.8E-22 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LH59_09695 37109b78d2bb4caa305fc52fdbcd4e11 143 SMART SM00422 19 89 6.0E-9 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LH59_05465 6d2e9b5410fa6a3b5a88741e88e4d6de 319 SUPERFAMILY SSF51905 1 314 1.64E-54 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_05465 6d2e9b5410fa6a3b5a88741e88e4d6de 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 41 56 5.6E-73 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 LH59_05465 6d2e9b5410fa6a3b5a88741e88e4d6de 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 130 142 5.6E-73 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 LH59_05465 6d2e9b5410fa6a3b5a88741e88e4d6de 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 200 216 5.6E-73 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 LH59_05465 6d2e9b5410fa6a3b5a88741e88e4d6de 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 108 116 5.6E-73 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 LH59_05465 6d2e9b5410fa6a3b5a88741e88e4d6de 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 277 295 5.6E-73 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 LH59_05465 6d2e9b5410fa6a3b5a88741e88e4d6de 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 145 169 5.6E-73 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 LH59_05465 6d2e9b5410fa6a3b5a88741e88e4d6de 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 239 260 5.6E-73 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 LH59_05465 6d2e9b5410fa6a3b5a88741e88e4d6de 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 5.6E-73 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 LH59_05465 6d2e9b5410fa6a3b5a88741e88e4d6de 319 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 62 72 5.6E-73 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 LH59_05465 6d2e9b5410fa6a3b5a88741e88e4d6de 319 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 301 1.5E-48 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 LH59_05465 6d2e9b5410fa6a3b5a88741e88e4d6de 319 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 8 314 7.6E-119 T 14-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 LH59_05465 6d2e9b5410fa6a3b5a88741e88e4d6de 319 Gene3D G3DSA:3.50.50.60 119 245 7.6E-124 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_05465 6d2e9b5410fa6a3b5a88741e88e4d6de 319 Gene3D G3DSA:3.50.50.60 10 313 7.6E-124 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_05465 6d2e9b5410fa6a3b5a88741e88e4d6de 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 3.8E-39 T 14-10-2018 LH59_05465 6d2e9b5410fa6a3b5a88741e88e4d6de 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 3.8E-39 T 14-10-2018 LH59_05465 6d2e9b5410fa6a3b5a88741e88e4d6de 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 237 253 3.8E-39 T 14-10-2018 LH59_05465 6d2e9b5410fa6a3b5a88741e88e4d6de 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 3.8E-39 T 14-10-2018 LH59_05465 6d2e9b5410fa6a3b5a88741e88e4d6de 319 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 267 289 3.8E-39 T 14-10-2018 LH59_05465 6d2e9b5410fa6a3b5a88741e88e4d6de 319 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 137 157 - T 14-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 LH59_13420 22fb0ee9574c5b45ad26dc6fe8c9cdae 147 SUPERFAMILY SSF54523 1 86 2.12E-11 T 14-10-2018 LH59_13420 22fb0ee9574c5b45ad26dc6fe8c9cdae 147 TIGRFAM TIGR01708 typeII_sec_gspH: type II secretion system protein H 1 144 2.3E-26 T 14-10-2018 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 LH59_21335 cc3b4948cd49fadb7da83cd62dc1a7bb 437 Gene3D G3DSA:1.20.140.90 41 154 3.6E-33 T 14-10-2018 IPR038351 Malonyl-CoA decarboxylase, N-terminal domain superfamily KEGG: 00410+4.1.1.9|KEGG: 00640+4.1.1.9|Reactome: R-HSA-390247|Reactome: R-HSA-9033241 LH59_21335 cc3b4948cd49fadb7da83cd62dc1a7bb 437 Pfam PF05292 Malonyl-CoA decarboxylase C-terminal domain 156 411 2.5E-102 T 14-10-2018 IPR007956 Malonyl-CoA decarboxylase, C-terminal GO:0006633|GO:0050080 KEGG: 00410+4.1.1.9|KEGG: 00640+4.1.1.9|Reactome: R-HSA-390247|Reactome: R-HSA-9033241 LH59_21335 cc3b4948cd49fadb7da83cd62dc1a7bb 437 Gene3D G3DSA:3.40.630.150 155 437 3.9E-106 T 14-10-2018 LH59_21335 cc3b4948cd49fadb7da83cd62dc1a7bb 437 Pfam PF17408 Malonyl-CoA decarboxylase N-terminal domain 104 153 7.8E-13 T 14-10-2018 IPR035372 Malonyl-CoA decarboxylase, N-terminal KEGG: 00410+4.1.1.9|KEGG: 00640+4.1.1.9|Reactome: R-HSA-390247|Reactome: R-HSA-9033241 LH59_23470 17b3c3b4739ac218753986fe484d0be9 231 Gene3D G3DSA:2.60.120.620 18 227 5.2E-9 T 14-10-2018 LH59_23470 17b3c3b4739ac218753986fe484d0be9 231 Pfam PF09859 Oxygenase, catalysing oxidative methylation of damaged DNA 60 230 2.3E-83 T 14-10-2018 IPR018655 Protein of unknown function DUF2086 LH59_18245 3a7f482bdc77e54b0c92f17a7496d193 141 Gene3D G3DSA:2.60.120.10 39 126 2.1E-14 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_18245 3a7f482bdc77e54b0c92f17a7496d193 141 Pfam PF07883 Cupin domain 64 124 6.8E-9 T 14-10-2018 IPR013096 Cupin 2, conserved barrel LH59_18245 3a7f482bdc77e54b0c92f17a7496d193 141 SUPERFAMILY SSF51182 64 124 1.17E-11 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_12190 f7f27a3a7d262a1b3e5321a8c53c9884 191 Pfam PF04471 Restriction endonuclease 81 186 2.4E-18 T 14-10-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 LH59_12190 f7f27a3a7d262a1b3e5321a8c53c9884 191 SUPERFAMILY SSF52980 83 189 7.51E-10 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 LH59_16155 58e22c4b836bd95e73a8960cc2764efa 143 Pfam PF00583 Acetyltransferase (GNAT) family 31 123 1.7E-16 T 14-10-2018 IPR000182 GNAT domain LH59_16155 58e22c4b836bd95e73a8960cc2764efa 143 Gene3D G3DSA:3.40.630.30 4 129 3.0E-20 T 14-10-2018 LH59_16155 58e22c4b836bd95e73a8960cc2764efa 143 SUPERFAMILY SSF55729 9 129 1.86E-22 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_01235 633bcc49e65d1ad151a104da42e5cf56 159 SUPERFAMILY SSF46785 2 140 2.72E-25 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_01235 633bcc49e65d1ad151a104da42e5cf56 159 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 140 2.0E-26 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type LH59_01235 633bcc49e65d1ad151a104da42e5cf56 159 Gene3D G3DSA:1.10.10.10 1 154 2.3E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_01235 633bcc49e65d1ad151a104da42e5cf56 159 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 14-10-2018 IPR030489 Transcription regulator Rrf2-type, conserved site LH59_01235 633bcc49e65d1ad151a104da42e5cf56 159 Pfam PF02082 Transcriptional regulator 1 83 9.7E-21 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type LH59_11390 1b467e582ee26bed65081a7b99bbc42a 237 Pfam PF13144 Chaperone for flagella basal body P-ring formation 41 235 2.9E-47 T 14-10-2018 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal LH59_11390 1b467e582ee26bed65081a7b99bbc42a 237 TIGRFAM TIGR03170 flgA_cterm: flagella basal body P-ring formation protein FlgA 101 236 6.6E-38 T 14-10-2018 IPR017585 Flagella basal body P-ring formation protein FlgA, C-terminal LH59_11390 1b467e582ee26bed65081a7b99bbc42a 237 Gene3D G3DSA:2.30.30.760 179 237 1.0E-19 T 14-10-2018 LH59_11390 1b467e582ee26bed65081a7b99bbc42a 237 SMART SM00858 113 175 5.1E-9 T 14-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 LH59_16285 96e52f1135b6094d22840c1ff8853cba 285 Pfam PF13679 Methyltransferase domain 35 179 7.0E-44 T 14-10-2018 IPR025714 Methyltransferase domain LH59_16285 96e52f1135b6094d22840c1ff8853cba 285 Gene3D G3DSA:3.40.50.150 60 199 7.3E-6 T 14-10-2018 LH59_16285 96e52f1135b6094d22840c1ff8853cba 285 SUPERFAMILY SSF53335 42 177 1.67E-12 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_21815 36321198eef8fcccfe651d62f6987ea0 74 Gene3D G3DSA:1.20.58.660 1 73 7.4E-26 T 14-10-2018 LH59_21815 36321198eef8fcccfe651d62f6987ea0 74 Pfam PF04325 Protein of unknown function (DUF465) 19 66 6.5E-17 T 14-10-2018 IPR007420 Protein of unknown function DUF465 LH59_04245 61d7b81b1841e3ad705e09d77841fe3d 146 Gene3D G3DSA:1.10.10.10 1 82 3.3E-27 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_04245 61d7b81b1841e3ad705e09d77841fe3d 146 SUPERFAMILY SSF46785 5 132 6.23E-38 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_04245 61d7b81b1841e3ad705e09d77841fe3d 146 Gene3D G3DSA:3.30.1490.190 83 136 8.0E-16 T 14-10-2018 LH59_04245 61d7b81b1841e3ad705e09d77841fe3d 146 Pfam PF01475 Ferric uptake regulator family 9 128 1.8E-37 T 14-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 LH59_25315 291909f34e6f5903cc7ea968998f51d3 320 Pfam PF00682 HMGL-like 9 277 7.3E-48 T 14-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 LH59_25315 291909f34e6f5903cc7ea968998f51d3 320 SUPERFAMILY SSF51569 9 297 2.64E-74 T 14-10-2018 LH59_25315 291909f34e6f5903cc7ea968998f51d3 320 Gene3D G3DSA:3.20.20.70 7 283 8.9E-114 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_23855 4f9c63564296d380128303c7442e75d1 300 SUPERFAMILY SSF53850 90 296 2.64E-41 T 14-10-2018 LH59_23855 4f9c63564296d380128303c7442e75d1 300 SUPERFAMILY SSF46785 4 112 4.09E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_23855 4f9c63564296d380128303c7442e75d1 300 Pfam PF03466 LysR substrate binding domain 89 293 5.4E-40 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_23855 4f9c63564296d380128303c7442e75d1 300 Gene3D G3DSA:1.10.10.10 3 90 8.3E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_23855 4f9c63564296d380128303c7442e75d1 300 Gene3D G3DSA:3.40.190.10 164 264 2.8E-62 T 14-10-2018 LH59_23855 4f9c63564296d380128303c7442e75d1 300 Gene3D G3DSA:3.40.190.10 93 291 2.8E-62 T 14-10-2018 LH59_23855 4f9c63564296d380128303c7442e75d1 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 2.8E-16 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_10230 f369ea44ed0cc3ba548ce8c4d8189ffa 464 TIGRFAM TIGR00797 matE: MATE efflux family protein 22 429 5.0E-76 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 LH59_10230 f369ea44ed0cc3ba548ce8c4d8189ffa 464 Pfam PF01554 MatE 22 183 1.8E-29 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 LH59_10230 f369ea44ed0cc3ba548ce8c4d8189ffa 464 Pfam PF01554 MatE 250 414 4.2E-26 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 LH59_10230 f369ea44ed0cc3ba548ce8c4d8189ffa 464 PIRSF PIRSF006603 6 453 2.0E-59 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 LH59_14410 c4b2333793a007da933059c22453c5c4 576 Gene3D G3DSA:3.50.30.80 377 531 1.4E-47 T 14-10-2018 LH59_14410 c4b2333793a007da933059c22453c5c4 576 Pfam PF00920 Dehydratase family 41 557 7.8E-179 T 14-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 LH59_14410 c4b2333793a007da933059c22453c5c4 576 SUPERFAMILY SSF52016 378 563 1.1E-57 T 14-10-2018 LH59_14410 c4b2333793a007da933059c22453c5c4 576 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 124 134 - T 14-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 LH59_14410 c4b2333793a007da933059c22453c5c4 576 SUPERFAMILY SSF143975 4 376 5.89E-125 T 14-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 LH59_18745 224812131ef72a5aba32501d2814247f 67 SMART SM00357 3 67 2.9E-23 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 LH59_18745 224812131ef72a5aba32501d2814247f 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 14-10-2018 IPR019844 Cold-shock conserved site LH59_18745 224812131ef72a5aba32501d2814247f 67 Gene3D G3DSA:2.40.50.140 1 66 4.4E-24 T 14-10-2018 LH59_18745 224812131ef72a5aba32501d2814247f 67 SUPERFAMILY SSF50249 1 66 1.47E-22 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_18745 224812131ef72a5aba32501d2814247f 67 PIRSF PIRSF002599 1 67 2.6E-20 T 14-10-2018 IPR012156 Cold shock, CspA GO:0003676 LH59_18745 224812131ef72a5aba32501d2814247f 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 7.6E-25 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 LH59_18745 224812131ef72a5aba32501d2814247f 67 PRINTS PR00050 Cold shock protein signature 40 58 3.8E-12 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 LH59_18745 224812131ef72a5aba32501d2814247f 67 PRINTS PR00050 Cold shock protein signature 25 34 3.8E-12 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 LH59_18745 224812131ef72a5aba32501d2814247f 67 PRINTS PR00050 Cold shock protein signature 4 19 3.8E-12 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 LH59_10935 074b9035d961553a16d15b3a0c72864d 433 Pfam PF07690 Major Facilitator Superfamily 28 389 4.6E-48 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_10935 074b9035d961553a16d15b3a0c72864d 433 SUPERFAMILY SSF103473 11 425 1.16E-80 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_10935 074b9035d961553a16d15b3a0c72864d 433 Gene3D G3DSA:1.20.1250.20 9 427 1.6E-80 T 14-10-2018 LH59_20380 89af0c62953c1f610a743b00ea81078f 276 Pfam PF12679 ABC-2 family transporter protein 6 274 4.8E-52 T 14-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 LH59_13355 170d774d3b4c254a1a3480709436ab7c 198 Pfam PF04612 Type II secretion system (T2SS), protein M 33 171 1.2E-15 T 14-10-2018 IPR007690 Type II secretion system, protein M GO:0009306 LH59_18085 fb6deacf8f73588a0b114b38ae5b2099 342 TIGRFAM TIGR02305 HpaG-N-term: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, N-terminal subunit 134 337 1.5E-74 T 14-10-2018 IPR012686 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, N-terminal subunit GO:0008704|GO:0018800 KEGG: 00350+5.3.3.10+4.1.1.68 LH59_18085 fb6deacf8f73588a0b114b38ae5b2099 342 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 135 338 4.8E-37 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 LH59_18085 fb6deacf8f73588a0b114b38ae5b2099 342 Gene3D G3DSA:3.30.429.10 1 128 4.9E-41 T 14-10-2018 IPR014347 Tautomerase/MIF superfamily LH59_18085 fb6deacf8f73588a0b114b38ae5b2099 342 SUPERFAMILY SSF55331 2 124 5.95E-30 T 14-10-2018 IPR014347 Tautomerase/MIF superfamily LH59_18085 fb6deacf8f73588a0b114b38ae5b2099 342 Pfam PF02962 5-carboxymethyl-2-hydroxymuconate isomerase 2 119 1.1E-14 T 14-10-2018 IPR004220 5-carboxymethyl-2-hydroxymuconate isomerase GO:0008704|GO:0019439 KEGG: 00350+5.3.3.10 LH59_18085 fb6deacf8f73588a0b114b38ae5b2099 342 SUPERFAMILY SSF56529 132 339 7.33E-47 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 LH59_18085 fb6deacf8f73588a0b114b38ae5b2099 342 Gene3D G3DSA:3.90.850.10 133 341 2.6E-45 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 LH59_05930 aa408e5387c51d20e29249febbaef876 102 Pfam PF06906 Protein of unknown function (DUF1272) 1 57 1.4E-29 T 14-10-2018 IPR010696 Protein of unknown function DUF1272 LH59_19070 d42c8dddf832081339fa2af4332b0106 127 Gene3D G3DSA:3.10.180.10 1 126 1.5E-38 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_19070 d42c8dddf832081339fa2af4332b0106 127 SUPERFAMILY SSF54593 2 126 1.24E-23 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_19070 d42c8dddf832081339fa2af4332b0106 127 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 121 7.0E-11 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain LH59_08425 10c817e403f7c9abcdf68ebd5a69a056 438 Gene3D G3DSA:3.90.1580.10 187 438 9.7E-37 T 14-10-2018 LH59_08425 10c817e403f7c9abcdf68ebd5a69a056 438 SUPERFAMILY SSF56436 190 437 6.12E-67 T 14-10-2018 IPR016187 C-type lectin fold LH59_08425 10c817e403f7c9abcdf68ebd5a69a056 438 Pfam PF03781 Sulfatase-modifying factor enzyme 1 192 436 5.8E-31 T 14-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 LH59_08425 10c817e403f7c9abcdf68ebd5a69a056 438 Pfam PF12867 DinB superfamily 26 160 4.4E-15 T 14-10-2018 IPR024775 DinB-like domain LH59_08425 10c817e403f7c9abcdf68ebd5a69a056 438 TIGRFAM TIGR03440 egtB_TIGR03440: ergothioneine biosynthesis protein EgtB 24 435 1.8E-165 T 14-10-2018 IPR017806 Ergothioneine biosynthesis protein EgtB GO:0052699 KEGG: 00340+1.14.99.50|MetaCyc: PWY-7255 LH59_08425 10c817e403f7c9abcdf68ebd5a69a056 438 SUPERFAMILY SSF109854 20 156 6.87E-6 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes LH59_26205 b75291af3ea2e7dd3eebecf15ed59a75 420 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 252 412 2.3E-40 T 14-10-2018 IPR031475 Four-carbon acid sugar kinase, C-terminal domain LH59_26205 b75291af3ea2e7dd3eebecf15ed59a75 420 Pfam PF07005 Putative sugar-binding N-terminal domain 5 228 1.1E-71 T 14-10-2018 IPR010737 Four-carbon acid sugar kinase, N-terminal domain LH59_26205 b75291af3ea2e7dd3eebecf15ed59a75 420 Gene3D G3DSA:3.40.980.20 240 419 2.6E-56 T 14-10-2018 LH59_26205 b75291af3ea2e7dd3eebecf15ed59a75 420 SUPERFAMILY SSF142764 5 417 3.53E-126 T 14-10-2018 LH59_26205 b75291af3ea2e7dd3eebecf15ed59a75 420 Gene3D G3DSA:3.40.50.10840 3 239 5.6E-88 T 14-10-2018 IPR037051 Four-carbon acid sugar kinase, N-terminal domain superfamily LH59_09015 ffc2e2630edc94481ff521e9d9a92f5a 403 Pfam PF04235 Protein of unknown function (DUF418) 229 389 1.6E-43 T 14-10-2018 IPR007349 Domain of unknown function DUF418 LH59_09260 29649ab985b6b7ac0a6e262216a869b4 379 Pfam PF01757 Acyltransferase family 9 353 5.0E-26 T 14-10-2018 IPR002656 Acyltransferase 3 GO:0016747 LH59_21235 a758a5714ee2f2ff67cf36e862dc9219 194 Pfam PF13590 Domain of unknown function (DUF4136) 21 178 1.1E-34 T 14-10-2018 IPR025411 Domain of unknown function DUF4136 LH59_21235 a758a5714ee2f2ff67cf36e862dc9219 194 Gene3D G3DSA:3.30.160.670 11 181 7.1E-43 T 14-10-2018 LH59_00525 0f849ffaf66cf189e9b096090b29d095 113 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 36 83 2.5E-10 T 14-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal LH59_00525 0f849ffaf66cf189e9b096090b29d095 113 SUPERFAMILY SSF50249 5 101 1.32E-19 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_07940 b502af611b35a7c3e016ca745819ac6b 299 Hamap MF_00194 Recombination-associated protein RdgC [rdgC]. 1 298 36.415 T 14-10-2018 IPR007476 Putative exonuclease, RdgC GO:0006310 LH59_07940 b502af611b35a7c3e016ca745819ac6b 299 Pfam PF04381 Putative exonuclease, RdgC 1 296 5.2E-117 T 14-10-2018 IPR007476 Putative exonuclease, RdgC GO:0006310 LH59_08260 80fc3660b9e0e1501cbe407af7419819 234 Pfam PF11254 Protein of unknown function (DUF3053) 12 224 4.0E-48 T 14-10-2018 IPR021413 Protein of unknown function DUF3053 LH59_14140 991b39497261bc6e9ab556f9c85ba4f3 217 Gene3D G3DSA:1.10.3720.10 2 215 2.7E-55 T 14-10-2018 IPR035906 MetI-like superfamily LH59_14140 991b39497261bc6e9ab556f9c85ba4f3 217 SUPERFAMILY SSF161098 11 206 4.06E-43 T 14-10-2018 IPR035906 MetI-like superfamily LH59_14140 991b39497261bc6e9ab556f9c85ba4f3 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 29 212 9.2E-24 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_14140 991b39497261bc6e9ab556f9c85ba4f3 217 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 9 108 5.4E-28 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 LH59_04745 ae55bc4508141db7318dfe30676182e3 103 Pfam PF00355 Rieske [2Fe-2S] domain 4 91 6.5E-19 T 14-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 LH59_04745 ae55bc4508141db7318dfe30676182e3 103 SUPERFAMILY SSF50022 3 103 4.06E-32 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 LH59_04745 ae55bc4508141db7318dfe30676182e3 103 Gene3D G3DSA:2.102.10.10 2 103 1.1E-34 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 LH59_04965 9183393ab225f63739700b6903be9d3f 305 SUPERFAMILY SSF63848 198 303 4.45E-30 T 14-10-2018 IPR036145 Septum formation inhibitor MinC, C-terminal domain superfamily GO:0000902 LH59_04965 9183393ab225f63739700b6903be9d3f 305 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 8 303 1.7E-55 T 14-10-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 LH59_04965 9183393ab225f63739700b6903be9d3f 305 Gene3D G3DSA:3.30.750.120 1 111 4.4E-21 T 14-10-2018 IPR038061 MinC, Proteobacteria, N-terminal domain superfamily LH59_04965 9183393ab225f63739700b6903be9d3f 305 Gene3D G3DSA:2.160.20.70 193 305 1.3E-33 T 14-10-2018 IPR016098 Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal GO:0000902 LH59_04965 9183393ab225f63739700b6903be9d3f 305 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 199 301 4.9E-31 T 14-10-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 LH59_04965 9183393ab225f63739700b6903be9d3f 305 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 7 304 26.108 T 14-10-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 LH59_04965 9183393ab225f63739700b6903be9d3f 305 Pfam PF05209 Septum formation inhibitor MinC, N-terminal domain 8 84 1.9E-16 T 14-10-2018 IPR007874 Septum formation inhibitor MinC, N-terminal GO:0051302 LH59_00550 93aea11fe8bcffc9602d50ec3f331986 265 SUPERFAMILY SSF46689 213 262 1.08E-5 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_00550 93aea11fe8bcffc9602d50ec3f331986 265 SMART SM00342 177 260 2.4E-13 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_00550 93aea11fe8bcffc9602d50ec3f331986 265 Gene3D G3DSA:1.10.10.60 165 264 5.3E-21 T 14-10-2018 LH59_00550 93aea11fe8bcffc9602d50ec3f331986 265 Pfam PF12833 Helix-turn-helix domain 183 262 1.0E-17 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 LH59_24240 a622ac74e60d461d7885764c8565c9b8 337 Gene3D G3DSA:3.50.30.50 61 335 1.3E-42 T 14-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 LH59_24240 a622ac74e60d461d7885764c8565c9b8 337 SUPERFAMILY SSF102198 71 334 9.68E-43 T 14-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 LH59_24240 a622ac74e60d461d7885764c8565c9b8 337 Pfam PF04199 Putative cyclase 73 270 7.3E-32 T 14-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 LH59_17330 9e4784e3e0f58063feaf16f31cf764a7 285 SUPERFAMILY SSF51569 7 279 2.93E-102 T 14-10-2018 LH59_17330 9e4784e3e0f58063feaf16f31cf764a7 285 Hamap MF_00056 2-dehydro-3-deoxyphosphooctonate aldolase [kdsA]. 14 278 49.945 T 14-10-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 LH59_17330 9e4784e3e0f58063feaf16f31cf764a7 285 Pfam PF00793 DAHP synthetase I family 11 276 3.8E-67 T 14-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 LH59_17330 9e4784e3e0f58063feaf16f31cf764a7 285 Gene3D G3DSA:3.20.20.70 2 284 3.0E-98 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_17330 9e4784e3e0f58063feaf16f31cf764a7 285 TIGRFAM TIGR01362 KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase 19 276 9.0E-118 T 14-10-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 LH59_18270 bb2105429f1999196968be109ef94541 408 Pfam PF07690 Major Facilitator Superfamily 22 241 2.1E-14 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_18270 bb2105429f1999196968be109ef94541 408 Pfam PF07690 Major Facilitator Superfamily 263 396 9.3E-13 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_18270 bb2105429f1999196968be109ef94541 408 SUPERFAMILY SSF103473 5 397 1.22E-38 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_18270 bb2105429f1999196968be109ef94541 408 Gene3D G3DSA:1.20.1250.20 8 393 3.5E-37 T 14-10-2018 LH59_19695 7e59f3612400fada7f5d2b5b2f50f7ea 309 SUPERFAMILY SSF46785 5 108 5.67E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_19695 7e59f3612400fada7f5d2b5b2f50f7ea 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 67 4.9E-16 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_19695 7e59f3612400fada7f5d2b5b2f50f7ea 309 Gene3D G3DSA:1.10.10.10 7 93 9.9E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_19695 7e59f3612400fada7f5d2b5b2f50f7ea 309 Gene3D G3DSA:3.40.190.290 96 299 2.0E-50 T 14-10-2018 LH59_19695 7e59f3612400fada7f5d2b5b2f50f7ea 309 SUPERFAMILY SSF53850 94 303 4.71E-36 T 14-10-2018 LH59_19695 7e59f3612400fada7f5d2b5b2f50f7ea 309 Pfam PF03466 LysR substrate binding domain 93 300 1.3E-34 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_03685 d3e7ec58cfbf855c6b8c5382b947f30d 300 Pfam PF02653 Branched-chain amino acid transport system / permease component 15 288 1.3E-34 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_15175 3a7ba74a42a4e44ce4d7ac90df831f02 336 Gene3D G3DSA:3.20.20.100 1 322 9.9E-105 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily LH59_15175 3a7ba74a42a4e44ce4d7ac90df831f02 336 SUPERFAMILY SSF51430 1 311 4.06E-94 T 14-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily LH59_15175 3a7ba74a42a4e44ce4d7ac90df831f02 336 PRINTS PR00069 Aldo-keto reductase signature 134 151 1.6E-5 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 LH59_15175 3a7ba74a42a4e44ce4d7ac90df831f02 336 PRINTS PR00069 Aldo-keto reductase signature 39 63 1.6E-5 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 LH59_15175 3a7ba74a42a4e44ce4d7ac90df831f02 336 PRINTS PR00069 Aldo-keto reductase signature 103 121 1.6E-5 T 14-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 LH59_15175 3a7ba74a42a4e44ce4d7ac90df831f02 336 Pfam PF00248 Aldo/keto reductase family 15 309 3.0E-62 T 14-10-2018 IPR023210 NADP-dependent oxidoreductase domain LH59_21765 44cd4b82b213726b868ccccab6bedd28 224 Gene3D G3DSA:1.10.10.1320 6 121 5.4E-5 T 14-10-2018 LH59_21765 44cd4b82b213726b868ccccab6bedd28 224 Pfam PF10099 Anti-sigma-K factor rskA 62 221 1.4E-26 T 14-10-2018 IPR018764 Anti-sigma K factor RskA GO:0005886|GO:0016021 LH59_13865 f61609feb22a3daacf81f447e7f82d38 382 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 5 375 2.2E-96 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 LH59_13865 f61609feb22a3daacf81f447e7f82d38 382 Gene3D G3DSA:3.40.640.10 2 247 2.6E-72 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_13865 f61609feb22a3daacf81f447e7f82d38 382 SUPERFAMILY SSF53383 18 376 9.35E-92 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_13865 f61609feb22a3daacf81f447e7f82d38 382 TIGRFAM TIGR01324 cysta_beta_ly_B: cystathionine beta-lyase 5 377 6.3E-119 T 14-10-2018 IPR006233 Cystathionine beta-lyase, bacterial GO:0004121|GO:0005737|GO:0006520 KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8 LH59_13865 f61609feb22a3daacf81f447e7f82d38 382 Gene3D G3DSA:3.90.1150.10 248 378 1.3E-30 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_13865 f61609feb22a3daacf81f447e7f82d38 382 PIRSF PIRSF001434 1 379 3.2E-112 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 LH59_13865 f61609feb22a3daacf81f447e7f82d38 382 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 189 203 - T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 LH59_03220 b896239f587b3ee23193a8ff7ac0a86b 375 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 123 332 7.1E-15 T 14-10-2018 IPR004299 Membrane bound O-acyl transferase, MBOAT LH59_03220 b896239f587b3ee23193a8ff7ac0a86b 375 PIRSF PIRSF016636 36 374 2.1E-73 T 14-10-2018 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB LH59_03330 1823ddc1ed838f45527aed0ab3886b82 454 Pfam PF01523 Putative modulator of DNA gyrase 38 327 1.5E-61 T 14-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 LH59_03330 1823ddc1ed838f45527aed0ab3886b82 454 Gene3D G3DSA:3.30.2290.10 6 236 1.5E-83 T 14-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal LH59_03330 1823ddc1ed838f45527aed0ab3886b82 454 SUPERFAMILY SSF111283 17 454 1.83E-122 T 14-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 LH59_22645 0cd5451f0f5b49e1b23e74cf370d6ac1 272 Pfam PF01464 Transglycosylase SLT domain 157 239 2.4E-13 T 14-10-2018 IPR008258 Transglycosylase SLT domain 1 LH59_22645 0cd5451f0f5b49e1b23e74cf370d6ac1 272 Gene3D G3DSA:1.10.530.10 132 259 1.6E-20 T 14-10-2018 LH59_22645 0cd5451f0f5b49e1b23e74cf370d6ac1 272 SUPERFAMILY SSF53955 140 256 7.19E-24 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily LH59_12920 c613df9e309c2e594e510a4bd7a80689 437 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 141 158 - T 14-10-2018 IPR006061 Solute-binding family 1, conserved site GO:0055085 LH59_12920 c613df9e309c2e594e510a4bd7a80689 437 Gene3D G3DSA:3.40.190.10 146 423 1.7E-141 T 14-10-2018 LH59_12920 c613df9e309c2e594e510a4bd7a80689 437 SUPERFAMILY SSF53850 22 426 3.49E-82 T 14-10-2018 LH59_12920 c613df9e309c2e594e510a4bd7a80689 437 Pfam PF13416 Bacterial extracellular solute-binding protein 45 361 8.5E-51 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein LH59_12920 c613df9e309c2e594e510a4bd7a80689 437 Gene3D G3DSA:3.40.190.10 30 383 1.7E-141 T 14-10-2018 LH59_03845 8bf72ccfdd03ef02a046a6a15933b5f0 159 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 15 154 3.4E-20 T 14-10-2018 IPR009936 Protein of unknown function DUF1468 LH59_06240 2f1130cf2fa788ad3bf91718059aa7f5 438 Pfam PF07690 Major Facilitator Superfamily 11 349 5.5E-20 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_06240 2f1130cf2fa788ad3bf91718059aa7f5 438 SUPERFAMILY SSF103473 3 413 2.22E-27 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_06240 2f1130cf2fa788ad3bf91718059aa7f5 438 Gene3D G3DSA:1.20.1250.20 2 412 2.5E-27 T 14-10-2018 LH59_05115 66bd65f3f11d3c139dd89d8673947c9d 249 Pfam PF03591 AzlC protein 33 177 1.8E-31 T 14-10-2018 IPR011606 Branched-chain amino acid transport, permease LH59_23930 b1a414749d7bd2ef30f2e97872cf82b9 416 Pfam PF07690 Major Facilitator Superfamily 34 243 3.1E-19 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_23930 b1a414749d7bd2ef30f2e97872cf82b9 416 PRINTS PR01035 Tetracycline resistance protein signature 322 342 2.1E-15 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 LH59_23930 b1a414749d7bd2ef30f2e97872cf82b9 416 PRINTS PR01035 Tetracycline resistance protein signature 161 183 2.1E-15 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 LH59_23930 b1a414749d7bd2ef30f2e97872cf82b9 416 PRINTS PR01035 Tetracycline resistance protein signature 270 290 2.1E-15 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 LH59_23930 b1a414749d7bd2ef30f2e97872cf82b9 416 PRINTS PR01035 Tetracycline resistance protein signature 34 50 2.1E-15 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 LH59_23930 b1a414749d7bd2ef30f2e97872cf82b9 416 PRINTS PR01035 Tetracycline resistance protein signature 189 209 2.1E-15 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 LH59_23930 b1a414749d7bd2ef30f2e97872cf82b9 416 PRINTS PR01035 Tetracycline resistance protein signature 357 380 2.1E-15 T 14-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 LH59_23930 b1a414749d7bd2ef30f2e97872cf82b9 416 Gene3D G3DSA:1.20.1250.20 20 409 1.1E-46 T 14-10-2018 LH59_23930 b1a414749d7bd2ef30f2e97872cf82b9 416 SUPERFAMILY SSF103473 22 407 1.57E-46 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_03350 07373ee1fde429aabfa25e905d98b2e7 288 Pfam PF02653 Branched-chain amino acid transport system / permease component 13 263 2.4E-37 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_09520 ae22bc33fab223d8d33e39632f919161 180 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 36 164 6.4E-27 T 14-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ LH59_08625 43da8f50110e23690c5c6ea8a22a7068 243 Gene3D G3DSA:1.10.510.10 144 238 1.7E-11 T 14-10-2018 LH59_08625 43da8f50110e23690c5c6ea8a22a7068 243 Hamap MF_00521 3-deoxy-D-manno-octulosonic acid kinase [kdkA]. 8 239 27.038 T 14-10-2018 IPR022826 3-deoxy-D-manno-octulosonic acid kinase GO:0016773 KEGG: 00540+2.7.1.166|MetaCyc: PWY-7675|MetaCyc: PWY-7676 LH59_08625 43da8f50110e23690c5c6ea8a22a7068 243 Pfam PF06293 Lipopolysaccharide kinase (Kdo/WaaP) family 44 218 1.1E-45 T 14-10-2018 LH59_08625 43da8f50110e23690c5c6ea8a22a7068 243 SUPERFAMILY SSF56112 44 194 1.34E-20 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily LH59_19185 7ff8187e086db00e04c34650a9a24c88 630 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 46 172 4.8E-26 T 14-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ LH59_19185 7ff8187e086db00e04c34650a9a24c88 630 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 222 623 6.0E-86 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 LH59_19185 7ff8187e086db00e04c34650a9a24c88 630 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 213 621 1.6E-96 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit LH59_27325 cb7e6c0016d6e5b166c7168b513660b5 369 Gene3D G3DSA:3.40.50.2000 155 340 3.9E-68 T 14-10-2018 LH59_27325 cb7e6c0016d6e5b166c7168b513660b5 369 SUPERFAMILY SSF53756 13 357 1.37E-66 T 14-10-2018 LH59_27325 cb7e6c0016d6e5b166c7168b513660b5 369 Gene3D G3DSA:3.40.50.2000 17 351 3.9E-68 T 14-10-2018 LH59_27325 cb7e6c0016d6e5b166c7168b513660b5 369 Pfam PF13477 Glycosyl transferase 4-like 2 132 1.7E-32 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 LH59_27325 cb7e6c0016d6e5b166c7168b513660b5 369 Pfam PF00534 Glycosyl transferases group 1 168 335 5.8E-38 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 LH59_25400 9a56fef4fa3639fc6d19c1d6e445eb29 343 Gene3D G3DSA:3.90.25.10 199 333 7.1E-71 T 14-10-2018 LH59_25400 9a56fef4fa3639fc6d19c1d6e445eb29 343 Pfam PF01370 NAD dependent epimerase/dehydratase family 17 255 3.8E-44 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 LH59_25400 9a56fef4fa3639fc6d19c1d6e445eb29 343 Gene3D G3DSA:3.40.50.720 18 324 7.1E-71 T 14-10-2018 LH59_25400 9a56fef4fa3639fc6d19c1d6e445eb29 343 SUPERFAMILY SSF51735 12 336 5.85E-71 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_13015 ba6ec09692c733c83f861cb930d2700d 411 SUPERFAMILY SSF53822 35 409 1.08E-77 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_13015 ba6ec09692c733c83f861cb930d2700d 411 Gene3D G3DSA:3.40.50.2300 154 375 1.8E-96 T 14-10-2018 LH59_13015 ba6ec09692c733c83f861cb930d2700d 411 Pfam PF13458 Periplasmic binding protein 35 374 6.3E-77 T 14-10-2018 IPR028081 Leucine-binding protein domain LH59_13015 ba6ec09692c733c83f861cb930d2700d 411 Gene3D G3DSA:3.40.50.2300 59 367 1.8E-96 T 14-10-2018 LH59_12485 66e3d9e7c32403e92f416452d2488f2b 317 SUPERFAMILY SSF103481 205 304 1.44E-15 T 14-10-2018 LH59_12485 66e3d9e7c32403e92f416452d2488f2b 317 Pfam PF00892 EamA-like transporter family 164 294 3.2E-10 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_12485 66e3d9e7c32403e92f416452d2488f2b 317 Pfam PF00892 EamA-like transporter family 22 154 7.8E-8 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_12485 66e3d9e7c32403e92f416452d2488f2b 317 SUPERFAMILY SSF103481 60 158 4.58E-9 T 14-10-2018 LH59_24135 906a27c869be073bcc70fca83aa6ae2f 323 SUPERFAMILY SSF103481 202 302 2.62E-11 T 14-10-2018 LH59_24135 906a27c869be073bcc70fca83aa6ae2f 323 Pfam PF00892 EamA-like transporter family 12 142 3.6E-18 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_24135 906a27c869be073bcc70fca83aa6ae2f 323 Pfam PF00892 EamA-like transporter family 158 296 6.3E-20 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_24135 906a27c869be073bcc70fca83aa6ae2f 323 SUPERFAMILY SSF103481 41 146 6.93E-14 T 14-10-2018 LH59_15115 89ee26bf58b56eea3312e7c06bdff130 388 Gene3D G3DSA:3.40.50.2300 32 356 5.5E-102 T 14-10-2018 LH59_15115 89ee26bf58b56eea3312e7c06bdff130 388 SUPERFAMILY SSF53822 29 372 3.93E-88 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_15115 89ee26bf58b56eea3312e7c06bdff130 388 Pfam PF13458 Periplasmic binding protein 29 367 2.4E-80 T 14-10-2018 IPR028081 Leucine-binding protein domain LH59_15115 89ee26bf58b56eea3312e7c06bdff130 388 Gene3D G3DSA:3.40.50.2300 145 373 5.5E-102 T 14-10-2018 LH59_20500 dc3ac8d2858da904c3aa0b8d8d1b550e 184 Gene3D G3DSA:3.40.50.360 4 183 4.5E-48 T 14-10-2018 IPR029039 Flavoprotein-like superfamily LH59_20500 dc3ac8d2858da904c3aa0b8d8d1b550e 184 SUPERFAMILY SSF52218 5 175 2.44E-43 T 14-10-2018 IPR029039 Flavoprotein-like superfamily LH59_20500 dc3ac8d2858da904c3aa0b8d8d1b550e 184 Pfam PF03358 NADPH-dependent FMN reductase 5 148 2.8E-33 T 14-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 LH59_11475 a3484f5332e050f5afe299b5d981b2cc 89 PIRSF PIRSF004669 1 89 9.1E-31 T 14-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 LH59_11475 a3484f5332e050f5afe299b5d981b2cc 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 1.6E-21 T 14-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 LH59_11475 a3484f5332e050f5afe299b5d981b2cc 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 1.6E-21 T 14-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 LH59_11475 a3484f5332e050f5afe299b5d981b2cc 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 1.6E-21 T 14-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 LH59_11475 a3484f5332e050f5afe299b5d981b2cc 89 Pfam PF01313 Bacterial export proteins, family 3 6 77 1.3E-28 T 14-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 LH59_11475 a3484f5332e050f5afe299b5d981b2cc 89 TIGRFAM TIGR01402 fliQ: flagellar biosynthetic protein FliQ 1 86 2.0E-30 T 14-10-2018 IPR006305 Flagellar biosynthesis protein FliQ GO:0016021|GO:0044780 LH59_01590 be2d9c1bcac9938e478c33d8e5a1218a 290 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 275 2.0E-32 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_01590 be2d9c1bcac9938e478c33d8e5a1218a 290 Gene3D G3DSA:1.10.3720.10 65 277 1.8E-25 T 14-10-2018 IPR035906 MetI-like superfamily LH59_01590 be2d9c1bcac9938e478c33d8e5a1218a 290 SUPERFAMILY SSF161098 69 258 3.92E-30 T 14-10-2018 IPR035906 MetI-like superfamily LH59_08105 a3f9e967efd44450f0603b398a747303 154 SUPERFAMILY SSF52833 2 153 1.37E-47 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_08105 a3f9e967efd44450f0603b398a747303 154 Pfam PF00578 AhpC/TSA family 5 131 2.9E-33 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 LH59_08105 a3f9e967efd44450f0603b398a747303 154 Gene3D G3DSA:3.40.30.10 2 152 1.5E-43 T 14-10-2018 LH59_08105 a3f9e967efd44450f0603b398a747303 154 PIRSF PIRSF000239 1 153 8.1E-29 T 14-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 LH59_15335 4ccd23dda28a43d5485b1c9dc36ec7ad 269 Pfam PF10127 Predicted nucleotidyltransferase 15 259 7.2E-87 T 14-10-2018 IPR018775 Nucleotidyltransferase, predicted LH59_12850 6e8268f478f444fb1c17a69269c4e672 446 PRINTS PR00164 ABC-2 type transport system membrane protein signature 220 241 7.7E-9 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 LH59_12850 6e8268f478f444fb1c17a69269c4e672 446 PRINTS PR00164 ABC-2 type transport system membrane protein signature 385 404 7.7E-9 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 LH59_12850 6e8268f478f444fb1c17a69269c4e672 446 PRINTS PR00164 ABC-2 type transport system membrane protein signature 365 384 7.7E-9 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 LH59_12850 6e8268f478f444fb1c17a69269c4e672 446 PRINTS PR00164 ABC-2 type transport system membrane protein signature 328 352 7.7E-9 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 LH59_12850 6e8268f478f444fb1c17a69269c4e672 446 Pfam PF01061 ABC-2 type transporter 202 408 1.4E-9 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 LH59_26830 4a281a244a4d562538f34c6981bda54f 640 Pfam PF00005 ABC transporter 405 565 1.2E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_26830 4a281a244a4d562538f34c6981bda54f 640 Pfam PF02653 Branched-chain amino acid transport system / permease component 29 275 3.7E-42 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_26830 4a281a244a4d562538f34c6981bda54f 640 SMART SM00382 414 622 4.6E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_26830 4a281a244a4d562538f34c6981bda54f 640 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 614 636 2.6E-9 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal LH59_26830 4a281a244a4d562538f34c6981bda54f 640 Gene3D G3DSA:3.40.50.300 385 637 3.6E-59 T 14-10-2018 LH59_26830 4a281a244a4d562538f34c6981bda54f 640 SUPERFAMILY SSF52540 388 635 1.91E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_03725 b3c4661a70a7d44a6336e8d710147cec 230 Pfam PF04172 LrgB-like family 14 225 1.5E-65 T 14-10-2018 IPR007300 CidB/LrgB family LH59_23110 22ae54b5fcb9ca02078b7ba08b9b1238 232 SMART SM00382 26 211 5.9E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_23110 22ae54b5fcb9ca02078b7ba08b9b1238 232 Pfam PF00005 ABC transporter 17 161 6.0E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_23110 22ae54b5fcb9ca02078b7ba08b9b1238 232 Gene3D G3DSA:3.40.50.300 1 227 6.0E-60 T 14-10-2018 LH59_23110 22ae54b5fcb9ca02078b7ba08b9b1238 232 SUPERFAMILY SSF52540 2 221 1.5E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_23110 22ae54b5fcb9ca02078b7ba08b9b1238 232 TIGRFAM TIGR03410 urea_trans_UrtE: urea ABC transporter, ATP-binding protein UrtE 2 232 1.2E-104 T 14-10-2018 IPR017780 ABC transporter, urea, ATP-binding protein, UrtE LH59_27135 b63d3c8263c766445ee888baa8403f32 225 SUPERFAMILY SSF55781 85 217 3.27E-6 T 14-10-2018 LH59_27135 b63d3c8263c766445ee888baa8403f32 225 Gene3D G3DSA:3.30.450.40 41 221 5.6E-45 T 14-10-2018 IPR029016 GAF-like domain superfamily LH59_27135 b63d3c8263c766445ee888baa8403f32 225 Pfam PF04340 Protein of unknown function, DUF484 2 217 1.1E-30 T 14-10-2018 IPR007435 Protein of unknown function DUF484 LH59_13680 c4f90741e836507a0f415466e14f08cb 163 Gene3D G3DSA:3.10.450.50 4 163 1.9E-42 T 14-10-2018 LH59_13680 c4f90741e836507a0f415466e14f08cb 163 SUPERFAMILY SSF54427 9 162 1.05E-44 T 14-10-2018 IPR032710 NTF2-like domain superfamily LH59_13680 c4f90741e836507a0f415466e14f08cb 163 Pfam PF00866 Ring hydroxylating beta subunit 24 154 6.3E-16 T 14-10-2018 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0006725|GO:0055114 LH59_13570 879f03cf76f0334ff282ac7928ccb929 356 Pfam PF11740 Plasmid replication region DNA-binding N-term 6 121 1.9E-27 T 14-10-2018 IPR021104 KfrA, N-terminal DNA-binding domain LH59_16115 22f83743b454c4e92071e9082b96cf3b 206 Pfam PF09998 Uncharacterized protein conserved in bacteria (DUF2239) 8 200 3.2E-80 T 14-10-2018 IPR018715 Protein of unknown function DUF2239 LH59_09140 d0c127b005740f59fae6b2e553c7932c 429 SUPERFAMILY SSF51905 32 415 7.56E-52 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_09140 d0c127b005740f59fae6b2e553c7932c 429 Gene3D G3DSA:3.30.9.10 126 348 2.6E-77 T 14-10-2018 LH59_09140 d0c127b005740f59fae6b2e553c7932c 429 Gene3D G3DSA:3.50.50.60 33 386 2.6E-77 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_09140 d0c127b005740f59fae6b2e553c7932c 429 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 383 398 5.2E-7 T 14-10-2018 LH59_09140 d0c127b005740f59fae6b2e553c7932c 429 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 33 55 5.2E-7 T 14-10-2018 LH59_09140 d0c127b005740f59fae6b2e553c7932c 429 Pfam PF01266 FAD dependent oxidoreductase 33 385 2.3E-58 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 LH59_03560 b1372e3147d834820fe39a25fc027ed6 225 Pfam PF04391 Protein of unknown function (DUF533) 40 220 3.2E-62 T 14-10-2018 IPR007486 Inner membrane protein YebE LH59_03560 b1372e3147d834820fe39a25fc027ed6 225 Gene3D G3DSA:1.10.3680.10 104 225 1.8E-8 T 14-10-2018 IPR029024 TerB-like LH59_03560 b1372e3147d834820fe39a25fc027ed6 225 SUPERFAMILY SSF158682 75 223 8.11E-23 T 14-10-2018 IPR029024 TerB-like LH59_01305 b643c184679f43bdb3ebb6e0a1080f37 167 Pfam PF16068 Domain of unknown function (DUF4810) 39 123 2.8E-28 T 14-10-2018 IPR014508 Uncharacterised conserved protein withTPR-like repeats LH59_23370 047a0ac405be60ff01ca57d2e0234ff9 119 Pfam PF13663 Domain of unknown function (DUF4148) 79 107 1.7E-7 T 14-10-2018 IPR025421 Protein of unknown function DUF4148 LH59_23370 047a0ac405be60ff01ca57d2e0234ff9 119 Pfam PF13663 Domain of unknown function (DUF4148) 1 69 3.5E-11 T 14-10-2018 IPR025421 Protein of unknown function DUF4148 LH59_23820 bd084636460a8ba734a6cc3e30335e56 129 Gene3D G3DSA:2.102.10.10 12 125 4.0E-33 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 LH59_23820 bd084636460a8ba734a6cc3e30335e56 129 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 18 124 1.4E-28 T 14-10-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 LH59_23820 bd084636460a8ba734a6cc3e30335e56 129 Pfam PF13806 Rieske-like [2Fe-2S] domain 18 124 1.9E-35 T 14-10-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 LH59_23820 bd084636460a8ba734a6cc3e30335e56 129 SUPERFAMILY SSF50022 18 126 1.13E-32 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 LH59_21720 383b89841e8bd3473392559e226fad2e 111 PIRSF PIRSF028744 5 111 3.3E-31 T 14-10-2018 IPR014056 Addiction module killer protein, predicted LH59_21720 383b89841e8bd3473392559e226fad2e 111 TIGRFAM TIGR02683 upstrm_HI1419: putative addiction module killer protein 14 106 1.9E-28 T 14-10-2018 IPR014056 Addiction module killer protein, predicted LH59_13565 08fcb38ab9cab8944a88d78edd15c233 122 Gene3D G3DSA:1.10.890.40 31 122 2.4E-21 T 14-10-2018 LH59_20100 0422100d240878051d970690011dfd31 171 Gene3D G3DSA:1.10.10.10 1 163 8.6E-28 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_20100 0422100d240878051d970690011dfd31 171 Pfam PF01047 MarR family 38 96 9.8E-10 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_20100 0422100d240878051d970690011dfd31 171 SUPERFAMILY SSF46785 6 143 7.11E-26 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_20100 0422100d240878051d970690011dfd31 171 SMART SM00347 33 131 2.4E-13 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_20100 0422100d240878051d970690011dfd31 171 PRINTS PR00598 Bacterial regulatory protein MarR family signature 91 107 2.4E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_20100 0422100d240878051d970690011dfd31 171 PRINTS PR00598 Bacterial regulatory protein MarR family signature 55 71 2.4E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_20100 0422100d240878051d970690011dfd31 171 PRINTS PR00598 Bacterial regulatory protein MarR family signature 72 87 2.4E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_20100 0422100d240878051d970690011dfd31 171 PRINTS PR00598 Bacterial regulatory protein MarR family signature 121 141 2.4E-8 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 LH59_22225 71e5af7747435235bb7ef261df1a4d14 475 SUPERFAMILY SSF47240 107 332 3.08E-48 T 14-10-2018 IPR009078 Ferritin-like superfamily LH59_22225 71e5af7747435235bb7ef261df1a4d14 475 Gene3D G3DSA:1.10.620.20 3 475 6.5E-234 T 14-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 LH59_22225 71e5af7747435235bb7ef261df1a4d14 475 TIGRFAM TIGR03225 benzo_boxB: benzoyl-CoA oxygenase, B subunit 4 474 3.4E-270 T 14-10-2018 IPR017635 Benzoyl-CoA oxygenase, B subunit KEGG: 00362+1.14.13.208|MetaCyc: PWY-1361 LH59_05095 4deac0eee213785e3b31f50aad8d450e 366 SUPERFAMILY SSF53474 96 342 1.27E-32 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_05095 4deac0eee213785e3b31f50aad8d450e 366 Gene3D G3DSA:3.40.50.1820 82 351 1.2E-22 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_05095 4deac0eee213785e3b31f50aad8d450e 366 PIRSF PIRSF005211 3 366 9.9E-118 T 14-10-2018 IPR012020 AB hydrolase 4 family LH59_05095 4deac0eee213785e3b31f50aad8d450e 366 Pfam PF00561 alpha/beta hydrolase fold 103 345 6.7E-11 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_08640 52b2930fad3321ea068648dce83bc956 306 SUPERFAMILY SSF161098 15 292 2.09E-56 T 14-10-2018 IPR035906 MetI-like superfamily LH59_08640 52b2930fad3321ea068648dce83bc956 306 Gene3D G3DSA:1.10.3720.10 14 300 5.7E-55 T 14-10-2018 IPR035906 MetI-like superfamily LH59_08640 52b2930fad3321ea068648dce83bc956 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 287 1.0E-18 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_06830 5cfd6776f4088717831f4b4d49a030e3 281 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 12 225 3.6E-10 T 14-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 LH59_06830 5cfd6776f4088717831f4b4d49a030e3 281 SUPERFAMILY SSF56300 10 247 1.29E-31 T 14-10-2018 LH59_06830 5cfd6776f4088717831f4b4d49a030e3 281 Gene3D G3DSA:3.60.21.10 9 250 9.5E-19 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like LH59_06050 0597d753701d94d44f3132d20461a9d4 212 Pfam PF08361 MAATS-type transcriptional repressor, C-terminal region 92 173 1.6E-9 T 14-10-2018 IPR013572 Transcription regulator MAATS, C-terminal GO:0003677 LH59_06050 0597d753701d94d44f3132d20461a9d4 212 Gene3D G3DSA:1.10.357.10 1 211 2.6E-68 T 14-10-2018 LH59_06050 0597d753701d94d44f3132d20461a9d4 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 58 4.1E-12 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_06050 0597d753701d94d44f3132d20461a9d4 212 SUPERFAMILY SSF46689 1 71 6.16E-18 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 LH59_06050 0597d753701d94d44f3132d20461a9d4 212 SUPERFAMILY SSF48498 81 173 1.78E-7 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily LH59_06050 0597d753701d94d44f3132d20461a9d4 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 2.6E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_06050 0597d753701d94d44f3132d20461a9d4 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 2.6E-7 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 LH59_25785 9550ff14d91ea59c6d7e129d7c4207c3 495 Gene3D G3DSA:2.20.200.10 112 369 3.3E-132 T 14-10-2018 LH59_25785 9550ff14d91ea59c6d7e129d7c4207c3 495 Gene3D G3DSA:1.20.1600.10 65 481 3.3E-132 T 14-10-2018 LH59_25785 9550ff14d91ea59c6d7e129d7c4207c3 495 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 14 480 1.4E-121 T 14-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 LH59_25785 9550ff14d91ea59c6d7e129d7c4207c3 495 SUPERFAMILY SSF56954 3 483 7.98E-109 T 14-10-2018 LH59_25785 9550ff14d91ea59c6d7e129d7c4207c3 495 Pfam PF02321 Outer membrane efflux protein 75 267 1.2E-23 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 LH59_25785 9550ff14d91ea59c6d7e129d7c4207c3 495 Pfam PF02321 Outer membrane efflux protein 291 457 7.1E-29 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 LH59_20465 021bd70368b9c647ba2f868ead7c6f77 263 SUPERFAMILY SSF161098 65 248 4.84E-25 T 14-10-2018 IPR035906 MetI-like superfamily LH59_20465 021bd70368b9c647ba2f868ead7c6f77 263 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 256 7.0E-21 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_20465 021bd70368b9c647ba2f868ead7c6f77 263 Gene3D G3DSA:1.10.3720.10 63 259 1.9E-19 T 14-10-2018 IPR035906 MetI-like superfamily LH59_22255 1722222592b1f7de5146c0a6a7144fc6 281 SUPERFAMILY SSF53474 21 267 3.19E-45 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_22255 1722222592b1f7de5146c0a6a7144fc6 281 Gene3D G3DSA:3.40.50.1820 8 268 3.3E-42 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_22255 1722222592b1f7de5146c0a6a7144fc6 281 Pfam PF12697 Alpha/beta hydrolase family 39 262 1.6E-14 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_27245 be53a8e9b889ce197224e5105fbcfbb2 217 Pfam PF12695 Alpha/beta hydrolase family 106 202 1.6E-6 T 14-10-2018 IPR029059 Alpha/beta hydrolase fold-5 LH59_27245 be53a8e9b889ce197224e5105fbcfbb2 217 Gene3D G3DSA:3.40.50.1820 1 217 2.9E-46 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_27245 be53a8e9b889ce197224e5105fbcfbb2 217 SUPERFAMILY SSF53474 2 212 1.05E-38 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_17840 ff96ac3b8a0bdc5bf3e19ba4a630fdf6 266 SUPERFAMILY SSF52540 4 251 4.05E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_17840 ff96ac3b8a0bdc5bf3e19ba4a630fdf6 266 SMART SM00382 29 237 2.8E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_17840 ff96ac3b8a0bdc5bf3e19ba4a630fdf6 266 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 229 251 1.1E-10 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal LH59_17840 ff96ac3b8a0bdc5bf3e19ba4a630fdf6 266 Gene3D G3DSA:3.40.50.300 2 253 8.4E-64 T 14-10-2018 LH59_17840 ff96ac3b8a0bdc5bf3e19ba4a630fdf6 266 Pfam PF00005 ABC transporter 20 180 4.2E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_06790 8b11bf77cdfcc01e4e90f7e92c6afa0d 550 Pfam PF06418 CTP synthase N-terminus 3 270 7.8E-125 T 14-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 LH59_06790 8b11bf77cdfcc01e4e90f7e92c6afa0d 550 TIGRFAM TIGR00337 PyrG: CTP synthase 1 538 3.6E-241 T 14-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 LH59_06790 8b11bf77cdfcc01e4e90f7e92c6afa0d 550 Hamap MF_01227 CTP synthase [pyrG]. 2 543 51.107 T 14-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 LH59_06790 8b11bf77cdfcc01e4e90f7e92c6afa0d 550 SUPERFAMILY SSF52540 2 270 8.85E-121 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_06790 8b11bf77cdfcc01e4e90f7e92c6afa0d 550 Pfam PF00117 Glutamine amidotransferase class-I 305 537 6.3E-57 T 14-10-2018 IPR017926 Glutamine amidotransferase LH59_06790 8b11bf77cdfcc01e4e90f7e92c6afa0d 550 SUPERFAMILY SSF52317 292 544 3.73E-87 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_06790 8b11bf77cdfcc01e4e90f7e92c6afa0d 550 Gene3D G3DSA:3.40.50.300 1 289 3.3E-130 T 14-10-2018 LH59_06790 8b11bf77cdfcc01e4e90f7e92c6afa0d 550 Gene3D G3DSA:3.40.50.880 290 548 1.0E-102 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_11845 eeb77a97344ea2232e72f48d172dbc48 222 Gene3D G3DSA:1.10.3720.10 1 219 6.0E-60 T 14-10-2018 IPR035906 MetI-like superfamily LH59_11845 eeb77a97344ea2232e72f48d172dbc48 222 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 110 3.0E-29 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 LH59_11845 eeb77a97344ea2232e72f48d172dbc48 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 216 8.3E-24 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_11845 eeb77a97344ea2232e72f48d172dbc48 222 SUPERFAMILY SSF161098 15 201 2.49E-47 T 14-10-2018 IPR035906 MetI-like superfamily LH59_21590 c1f49f2d45ab27782402a975f3871d41 254 SUPERFAMILY SSF53639 19 220 1.18E-48 T 14-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily LH59_21590 c1f49f2d45ab27782402a975f3871d41 254 SMART SM01007 22 203 3.7E-38 T 14-10-2018 IPR001303 Class II aldolase/adducin N-terminal LH59_21590 c1f49f2d45ab27782402a975f3871d41 254 Gene3D G3DSA:3.40.225.10 13 251 4.0E-54 T 14-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily LH59_21590 c1f49f2d45ab27782402a975f3871d41 254 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 23 203 7.4E-36 T 14-10-2018 IPR001303 Class II aldolase/adducin N-terminal LH59_25080 41c8a01c53716080e63c9010235103cd 557 Gene3D G3DSA:1.10.275.10 12 221 1.2E-56 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal LH59_25080 41c8a01c53716080e63c9010235103cd 557 Pfam PF00221 Aromatic amino acid lyase 28 517 2.5E-127 T 14-10-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 LH59_25080 41c8a01c53716080e63c9010235103cd 557 Gene3D G3DSA:1.20.200.10 224 546 8.5E-79 T 14-10-2018 LH59_25080 41c8a01c53716080e63c9010235103cd 557 SUPERFAMILY SSF48557 19 543 2.04E-132 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 LH59_28210 5acd9d5324cb1c8127d70bf1a4e6e18b 348 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 258 344 2.4E-26 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_28210 5acd9d5324cb1c8127d70bf1a4e6e18b 348 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 260 324 2.0E-18 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 LH59_28210 5acd9d5324cb1c8127d70bf1a4e6e18b 348 Gene3D G3DSA:3.40.50.300 47 348 2.1E-95 T 14-10-2018 LH59_28210 5acd9d5324cb1c8127d70bf1a4e6e18b 348 SMART SM00382 66 266 7.3E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_28210 5acd9d5324cb1c8127d70bf1a4e6e18b 348 Pfam PF00005 ABC transporter 59 208 7.4E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_28210 5acd9d5324cb1c8127d70bf1a4e6e18b 348 SUPERFAMILY SSF52540 66 333 2.98E-67 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_28210 5acd9d5324cb1c8127d70bf1a4e6e18b 348 ProSitePatterns PS00211 ABC transporters family signature. 181 195 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_18925 c384f949030e5c9c303f2c5592448a89 139 Pfam PF02472 Biopolymer transport protein ExbD/TolR 18 136 2.9E-27 T 14-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 LH59_18925 c384f949030e5c9c303f2c5592448a89 139 Gene3D G3DSA:3.30.420.270 66 133 4.7E-12 T 14-10-2018 LH59_07945 30c2ad2da9a0c70ab592c8339c179a30 69 Pfam PF11381 Protein of unknown function (DUF3185) 2 61 3.4E-5 T 14-10-2018 IPR021521 Protein of unknown function DUF3185 LH59_04220 acf79a19699e69381f54ce69a809c90e 143 SUPERFAMILY SSF55298 14 142 2.04E-25 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 LH59_04220 acf79a19699e69381f54ce69a809c90e 143 Pfam PF01042 Endoribonuclease L-PSP 26 140 2.0E-17 T 14-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 LH59_04220 acf79a19699e69381f54ce69a809c90e 143 Gene3D G3DSA:3.30.1330.40 15 142 6.2E-26 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 LH59_00595 9d9768d49e3f004e2c9f95c31e973579 127 Pfam PF13411 MerR HTH family regulatory protein 7 70 8.8E-14 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LH59_00595 9d9768d49e3f004e2c9f95c31e973579 127 SMART SM00422 6 73 1.8E-17 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 LH59_00595 9d9768d49e3f004e2c9f95c31e973579 127 Gene3D G3DSA:1.10.1660.10 1 119 5.8E-26 T 14-10-2018 LH59_00595 9d9768d49e3f004e2c9f95c31e973579 127 SUPERFAMILY SSF46955 6 121 4.4E-24 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily LH59_18155 e80448f827b4d87800e30b3e11f01f8a 147 Gene3D G3DSA:3.30.530.20 2 146 5.9E-36 T 14-10-2018 IPR023393 START-like domain superfamily LH59_18155 e80448f827b4d87800e30b3e11f01f8a 147 SUPERFAMILY SSF55961 2 145 2.02E-28 T 14-10-2018 LH59_18155 e80448f827b4d87800e30b3e11f01f8a 147 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 3 145 2.8E-21 T 14-10-2018 IPR019587 Polyketide cyclase/dehydrase LH59_12540 514fc4f39b8e75de689529f13ae34973 329 Pfam PF02653 Branched-chain amino acid transport system / permease component 43 309 6.2E-34 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_03440 18ee153ab249e0b8ce244baab043139d 818 SUPERFAMILY SSF48452 358 456 5.61E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_03440 18ee153ab249e0b8ce244baab043139d 818 Gene3D G3DSA:1.25.40.10 334 479 2.9E-5 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_10460 ba8e8e3145516c1e97931eb67e9c820c 255 SUPERFAMILY SSF54862 53 233 3.35E-67 T 14-10-2018 LH59_10460 ba8e8e3145516c1e97931eb67e9c820c 255 Pfam PF13247 4Fe-4S dicluster domain 103 198 6.0E-29 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain LH59_10460 ba8e8e3145516c1e97931eb67e9c820c 255 Gene3D G3DSA:3.30.70.20 48 250 1.2E-67 T 14-10-2018 LH59_10460 ba8e8e3145516c1e97931eb67e9c820c 255 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 143 154 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site LH59_08735 3804af62121dbdfc82645ff66f373682 282 Pfam PF01522 Polysaccharide deacetylase 56 219 9.2E-34 T 14-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 LH59_08735 3804af62121dbdfc82645ff66f373682 282 Gene3D G3DSA:3.20.20.370 1 250 4.0E-61 T 14-10-2018 LH59_08735 3804af62121dbdfc82645ff66f373682 282 SUPERFAMILY SSF88713 21 248 1.98E-37 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 LH59_12730 b589b51110d3fc768d63f382fe461248 207 Gene3D G3DSA:3.90.950.10 8 207 1.4E-71 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like LH59_12730 b589b51110d3fc768d63f382fe461248 207 SUPERFAMILY SSF52972 10 204 1.78E-66 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like LH59_12730 b589b51110d3fc768d63f382fe461248 207 Pfam PF01725 Ham1 family 13 201 7.6E-53 T 14-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 LH59_12730 b589b51110d3fc768d63f382fe461248 207 Hamap MF_01405 dITP/XTP pyrophosphatase. 11 206 46.474 T 14-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 LH59_12730 b589b51110d3fc768d63f382fe461248 207 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 13 204 7.1E-50 T 14-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 LH59_15460 2aef9828f6d50e49e179acf715dfe7a0 174 Pfam PF05591 Type VI secretion system, VipA, VC_A0107 or Hcp2 12 164 2.2E-60 T 14-10-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 LH59_15460 2aef9828f6d50e49e179acf715dfe7a0 174 PIRSF PIRSF028301 2 174 6.1E-66 T 14-10-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 LH59_15460 2aef9828f6d50e49e179acf715dfe7a0 174 TIGRFAM TIGR03358 VI_chp_5: type VI secretion protein, VC_A0107 family 8 166 1.5E-58 T 14-10-2018 IPR008312 Type VI secretion system, VipA, VC_A0107 or Hcp2 LH59_13715 51baf1dc943c04e78524cd15500aa3a7 157 Pfam PF10027 Predicted integral membrane protein (DUF2269) 6 155 4.7E-60 T 14-10-2018 IPR018729 Protein of unknown function DUF2269, transmembrane LH59_05860 1a9e490f543dcc4db2e342dccd50b3af 360 Pfam PF13531 Bacterial extracellular solute-binding protein 46 312 8.5E-21 T 14-10-2018 LH59_05860 1a9e490f543dcc4db2e342dccd50b3af 360 Gene3D G3DSA:3.40.190.10 45 337 3.5E-113 T 14-10-2018 LH59_05860 1a9e490f543dcc4db2e342dccd50b3af 360 Gene3D G3DSA:3.40.190.10 146 350 3.5E-113 T 14-10-2018 LH59_05860 1a9e490f543dcc4db2e342dccd50b3af 360 SUPERFAMILY SSF53850 45 329 5.93E-42 T 14-10-2018 LH59_07715 623451d585193c02ab6bde5079a2365c 293 Gene3D G3DSA:3.30.2010.10 74 164 8.6E-31 T 14-10-2018 LH59_07715 623451d585193c02ab6bde5079a2365c 293 Hamap MF_00188 Protease HtpX [htpX]. 1 290 24.483 T 14-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 LH59_07715 623451d585193c02ab6bde5079a2365c 293 Pfam PF01435 Peptidase family M48 81 289 2.1E-38 T 14-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 LH59_17045 c2933cc385248b5cc0fd71b17d5d4c07 271 SUPERFAMILY SSF51556 2 260 2.87E-69 T 14-10-2018 IPR032466 Metal-dependent hydrolase LH59_17045 c2933cc385248b5cc0fd71b17d5d4c07 271 Gene3D G3DSA:3.20.20.140 1 261 1.8E-68 T 14-10-2018 LH59_17045 c2933cc385248b5cc0fd71b17d5d4c07 271 PIRSF PIRSF005902 1 263 1.7E-57 T 14-10-2018 IPR001130 TatD family GO:0016788 LH59_17045 c2933cc385248b5cc0fd71b17d5d4c07 271 Pfam PF01026 TatD related DNase 3 260 7.4E-60 T 14-10-2018 IPR001130 TatD family GO:0016788 LH59_17045 c2933cc385248b5cc0fd71b17d5d4c07 271 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 14-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 LH59_14265 cb96cd23ee972a81ee304ad686fe7082 208 Gene3D G3DSA:2.60.120.10 65 197 1.0E-20 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_14265 cb96cd23ee972a81ee304ad686fe7082 208 SUPERFAMILY SSF51182 14 196 4.75E-37 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_15265 301d8cc58fed81b0e807f1f3c5622eb8 135 Gene3D G3DSA:3.10.180.10 1 135 2.1E-58 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_15265 301d8cc58fed81b0e807f1f3c5622eb8 135 SUPERFAMILY SSF54593 6 130 1.88E-24 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_15810 b8298a007a2d75f2acd278e6488b450b 150 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 29 143 1.5E-21 T 14-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 LH59_15810 b8298a007a2d75f2acd278e6488b450b 150 Gene3D G3DSA:3.10.129.10 12 148 4.4E-36 T 14-10-2018 LH59_15810 b8298a007a2d75f2acd278e6488b450b 150 Pfam PF03061 Thioesterase superfamily 58 135 3.6E-14 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 LH59_15810 b8298a007a2d75f2acd278e6488b450b 150 SUPERFAMILY SSF54637 22 142 2.37E-33 T 14-10-2018 IPR029069 HotDog domain superfamily LH59_01295 117f8d9a2f859553e729e6a0792cf81c 302 Pfam PF14080 Domain of unknown function (DUF4261) 207 283 4.6E-15 T 14-10-2018 IPR025357 Domain of unknown function DUF4261 LH59_10620 15b44c34f91647fac6c909d7e6263947 199 SUPERFAMILY SSF54001 22 197 4.22E-43 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily LH59_10620 15b44c34f91647fac6c909d7e6263947 199 Gene3D G3DSA:3.90.1720.10 20 199 3.3E-68 T 14-10-2018 LH59_10620 15b44c34f91647fac6c909d7e6263947 199 Pfam PF05708 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family 22 196 2.4E-44 T 14-10-2018 IPR024453 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family LH59_18855 fbc6923cb6b976efd8398e47da0adbe2 380 SMART SM00091 16 82 1.4E-10 T 14-10-2018 IPR000014 PAS domain LH59_18855 fbc6923cb6b976efd8398e47da0adbe2 380 SMART SM00387 287 379 1.8E-4 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase LH59_18855 fbc6923cb6b976efd8398e47da0adbe2 380 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 17 142 3.2E-19 T 14-10-2018 IPR000014 PAS domain LH59_18855 fbc6923cb6b976efd8398e47da0adbe2 380 SUPERFAMILY SSF55874 248 375 2.1E-16 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_18855 fbc6923cb6b976efd8398e47da0adbe2 380 Gene3D G3DSA:3.30.450.20 14 152 1.6E-27 T 14-10-2018 LH59_18855 fbc6923cb6b976efd8398e47da0adbe2 380 Pfam PF13426 PAS domain 27 133 6.1E-13 T 14-10-2018 IPR000014 PAS domain LH59_18855 fbc6923cb6b976efd8398e47da0adbe2 380 SUPERFAMILY SSF55785 27 143 1.69E-22 T 14-10-2018 IPR035965 PAS domain superfamily LH59_18855 fbc6923cb6b976efd8398e47da0adbe2 380 Pfam PF07730 Histidine kinase 181 246 5.7E-14 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 LH59_18855 fbc6923cb6b976efd8398e47da0adbe2 380 Gene3D G3DSA:3.30.565.10 250 376 1.0E-29 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily LH59_03705 253a65b4e3323c54f244d2f41178265f 303 Pfam PF00701 Dihydrodipicolinate synthetase family 7 291 5.6E-56 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_03705 253a65b4e3323c54f244d2f41178265f 303 PIRSF PIRSF001365 2 302 3.0E-79 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_03705 253a65b4e3323c54f244d2f41178265f 303 Gene3D G3DSA:3.20.20.70 3 299 1.2E-81 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_03705 253a65b4e3323c54f244d2f41178265f 303 PRINTS PR00146 Dihydrodipicolinate synthase signature 39 60 5.7E-13 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_03705 253a65b4e3323c54f244d2f41178265f 303 PRINTS PR00146 Dihydrodipicolinate synthase signature 75 93 5.7E-13 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_03705 253a65b4e3323c54f244d2f41178265f 303 PRINTS PR00146 Dihydrodipicolinate synthase signature 132 149 5.7E-13 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_03705 253a65b4e3323c54f244d2f41178265f 303 SMART SM01130 5 293 2.1E-84 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_03705 253a65b4e3323c54f244d2f41178265f 303 SUPERFAMILY SSF51569 5 291 9.63E-82 T 14-10-2018 LH59_09860 415cdef232da4b83cb8d81952aae5f7f 328 Gene3D G3DSA:1.20.1530.20 1 317 1.8E-31 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily LH59_09860 415cdef232da4b83cb8d81952aae5f7f 328 PIRSF PIRSF026166 1 328 1.3E-118 T 14-10-2018 IPR016833 Putative sodium bile acid cotransporter LH59_09860 415cdef232da4b83cb8d81952aae5f7f 328 Pfam PF13593 SBF-like CPA transporter family (DUF4137) 7 314 4.9E-92 T 14-10-2018 IPR016833 Putative sodium bile acid cotransporter LH59_01765 54660760c8f070eb8981de2d983d1c3e 367 Gene3D G3DSA:3.10.620.30 112 286 2.4E-18 T 14-10-2018 LH59_01765 54660760c8f070eb8981de2d983d1c3e 367 Pfam PF01841 Transglutaminase-like superfamily 159 277 6.4E-23 T 14-10-2018 IPR002931 Transglutaminase-like LH59_01765 54660760c8f070eb8981de2d983d1c3e 367 SUPERFAMILY SSF54001 149 278 7.57E-22 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily LH59_01765 54660760c8f070eb8981de2d983d1c3e 367 SMART SM00460 205 279 1.3E-15 T 14-10-2018 IPR002931 Transglutaminase-like LH59_23935 edda3afe86b3c4e5d721416c0803cbe0 378 Gene3D G3DSA:3.40.50.880 51 281 5.4E-45 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_23935 edda3afe86b3c4e5d721416c0803cbe0 378 Pfam PF01965 DJ-1/PfpI family 60 223 1.5E-15 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 LH59_23935 edda3afe86b3c4e5d721416c0803cbe0 378 SUPERFAMILY SSF52317 67 238 1.61E-38 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_28220 2fcf53ed21b48f0896d1a3bfee462ae0 304 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 26 297 1.6E-64 T 14-10-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 LH59_28220 2fcf53ed21b48f0896d1a3bfee462ae0 304 SUPERFAMILY SSF51197 24 304 2.43E-85 T 14-10-2018 LH59_28220 2fcf53ed21b48f0896d1a3bfee462ae0 304 Gene3D G3DSA:3.60.130.10 23 304 3.8E-85 T 14-10-2018 LH59_16335 93d0f08a388bcafd7774be4fee72922e 281 SUPERFAMILY SSF51621 1 229 8.72E-55 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 LH59_16335 93d0f08a388bcafd7774be4fee72922e 281 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 2 219 2.6E-35 T 14-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 LH59_16335 93d0f08a388bcafd7774be4fee72922e 281 PIRSF PIRSF015582 1 281 4.0E-66 T 14-10-2018 IPR011206 Citrate lyase beta subunit-like LH59_16335 93d0f08a388bcafd7774be4fee72922e 281 Gene3D G3DSA:3.20.20.60 1 281 8.0E-76 T 14-10-2018 LH59_10630 79d4e397c695872d9289d1a0885f02c3 306 Gene3D G3DSA:1.10.10.10 3 88 2.7E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_10630 79d4e397c695872d9289d1a0885f02c3 306 Pfam PF03466 LysR substrate binding domain 87 291 4.1E-43 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_10630 79d4e397c695872d9289d1a0885f02c3 306 SUPERFAMILY SSF46785 4 110 1.05E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_10630 79d4e397c695872d9289d1a0885f02c3 306 SUPERFAMILY SSF53850 88 295 1.12E-43 T 14-10-2018 LH59_10630 79d4e397c695872d9289d1a0885f02c3 306 Gene3D G3DSA:3.40.190.290 89 292 1.1E-59 T 14-10-2018 LH59_10630 79d4e397c695872d9289d1a0885f02c3 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 2.3E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_09255 f75b116add36ba5df09886369410de94 306 Gene3D G3DSA:3.40.50.2000 142 296 2.4E-18 T 14-10-2018 LH59_09255 f75b116add36ba5df09886369410de94 306 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 136 266 4.2E-8 T 14-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 LH59_09255 f75b116add36ba5df09886369410de94 306 SUPERFAMILY SSF53756 12 295 3.45E-25 T 14-10-2018 LH59_09555 96b12bb5ede339ac550259b6a58acc2f 335 SUPERFAMILY SSF161098 95 313 6.93E-20 T 14-10-2018 IPR035906 MetI-like superfamily LH59_09555 96b12bb5ede339ac550259b6a58acc2f 335 Gene3D G3DSA:1.10.3720.10 89 322 2.1E-26 T 14-10-2018 IPR035906 MetI-like superfamily LH59_09555 96b12bb5ede339ac550259b6a58acc2f 335 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 326 4.4E-45 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_24160 7f5f2778640b2b132ef221eed8427bd2 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 71 7.5E-12 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_24160 7f5f2778640b2b132ef221eed8427bd2 304 Gene3D G3DSA:3.40.190.290 100 301 3.0E-40 T 14-10-2018 LH59_24160 7f5f2778640b2b132ef221eed8427bd2 304 Pfam PF03466 LysR substrate binding domain 98 295 6.4E-36 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_24160 7f5f2778640b2b132ef221eed8427bd2 304 SUPERFAMILY SSF53850 99 298 6.67E-33 T 14-10-2018 LH59_24160 7f5f2778640b2b132ef221eed8427bd2 304 Gene3D G3DSA:1.10.10.10 11 96 5.7E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_24160 7f5f2778640b2b132ef221eed8427bd2 304 SUPERFAMILY SSF46785 10 116 1.19E-14 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_11180 4bf8768a3c2d44ca15e96d13464aa284 206 Hamap MF_01632 Chorismate pyruvate-lyase [ubiC]. 13 189 24.452 T 14-10-2018 IPR007440 Chorismate--pyruvate lyase GO:0005737|GO:0006744|GO:0008813 KEGG: 00130+4.1.3.40|MetaCyc: PWY-5755|MetaCyc: PWY-5870|MetaCyc: PWY-6148|MetaCyc: PWY-7742|MetaCyc: PWY-7745|MetaCyc: PWY-7929|MetaCyc: PWY-7934|MetaCyc: PWY-7935 LH59_11180 4bf8768a3c2d44ca15e96d13464aa284 206 SUPERFAMILY SSF64288 11 187 2.51E-42 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily LH59_11180 4bf8768a3c2d44ca15e96d13464aa284 206 Gene3D G3DSA:3.40.1410.10 6 187 5.7E-36 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily LH59_11180 4bf8768a3c2d44ca15e96d13464aa284 206 Pfam PF04345 Chorismate lyase 23 188 1.4E-19 T 14-10-2018 IPR007440 Chorismate--pyruvate lyase GO:0005737|GO:0006744|GO:0008813 KEGG: 00130+4.1.3.40|MetaCyc: PWY-5755|MetaCyc: PWY-5870|MetaCyc: PWY-6148|MetaCyc: PWY-7742|MetaCyc: PWY-7745|MetaCyc: PWY-7929|MetaCyc: PWY-7934|MetaCyc: PWY-7935 LH59_13490 9ef95e288f34e404359ae3c0cb5ec999 333 SUPERFAMILY SSF56349 133 324 1.68E-34 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 LH59_13490 9ef95e288f34e404359ae3c0cb5ec999 333 Gene3D G3DSA:1.10.150.130 1 128 1.6E-14 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal LH59_13490 9ef95e288f34e404359ae3c0cb5ec999 333 Gene3D G3DSA:1.10.443.10 132 312 8.7E-38 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 LH59_13490 9ef95e288f34e404359ae3c0cb5ec999 333 Pfam PF00589 Phage integrase family 136 311 4.6E-15 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 LH59_13490 9ef95e288f34e404359ae3c0cb5ec999 333 SUPERFAMILY SSF47823 3 126 7.06E-12 T 14-10-2018 LH59_27700 582f3c1b6fed26a5a7752715497f01fd 293 Pfam PF00892 EamA-like transporter family 147 283 3.9E-20 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_27700 582f3c1b6fed26a5a7752715497f01fd 293 Pfam PF00892 EamA-like transporter family 4 135 1.1E-20 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_27700 582f3c1b6fed26a5a7752715497f01fd 293 SUPERFAMILY SSF103481 41 139 7.45E-14 T 14-10-2018 LH59_27700 582f3c1b6fed26a5a7752715497f01fd 293 SUPERFAMILY SSF103481 181 285 4.58E-13 T 14-10-2018 LH59_12965 7d99b3c3ae15448ee018a7766b2e9f94 247 TIGRFAM TIGR00035 asp_race: aspartate racemase 10 240 7.2E-45 T 14-10-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 LH59_12965 7d99b3c3ae15448ee018a7766b2e9f94 247 Pfam PF01177 Asp/Glu/Hydantoin racemase 13 232 1.3E-59 T 14-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 LH59_12965 7d99b3c3ae15448ee018a7766b2e9f94 247 Gene3D G3DSA:3.40.50.1860 111 224 5.9E-71 T 14-10-2018 LH59_12965 7d99b3c3ae15448ee018a7766b2e9f94 247 Gene3D G3DSA:3.40.50.1860 10 231 5.9E-71 T 14-10-2018 LH59_12965 7d99b3c3ae15448ee018a7766b2e9f94 247 SUPERFAMILY SSF53681 10 121 5.72E-30 T 14-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 LH59_12965 7d99b3c3ae15448ee018a7766b2e9f94 247 SUPERFAMILY SSF53681 125 237 1.64E-24 T 14-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 LH59_03245 d6cdf39f8070caac4b628a5406aef738 399 SUPERFAMILY SSF47240 63 370 5.95E-97 T 14-10-2018 IPR009078 Ferritin-like superfamily LH59_03245 d6cdf39f8070caac4b628a5406aef738 399 Gene3D G3DSA:1.10.620.20 54 392 1.4E-112 T 14-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 LH59_03245 d6cdf39f8070caac4b628a5406aef738 399 Pfam PF00268 Ribonucleotide reductase, small chain 79 366 1.4E-85 T 14-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 LH59_03245 d6cdf39f8070caac4b628a5406aef738 399 PIRSF PIRSF000355 53 399 3.7E-132 T 14-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 LH59_24525 612ca0c508cd61e6efec27628e577c28 259 Pfam PF02517 CAAX protease self-immunity 96 241 4.6E-8 T 14-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 LH59_11295 efec6a92210d239a018a13406319ae03 107 SUPERFAMILY SSF63592 6 99 2.09E-35 T 14-10-2018 IPR036194 Flagellar transcriptional activator FlhD superfamily LH59_11295 efec6a92210d239a018a13406319ae03 107 Gene3D G3DSA:1.10.4000.10 4 107 1.0E-38 T 14-10-2018 IPR036194 Flagellar transcriptional activator FlhD superfamily LH59_11295 efec6a92210d239a018a13406319ae03 107 Pfam PF05247 Flagellar transcriptional activator (FlhD) 6 104 1.2E-41 T 14-10-2018 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 LH59_11295 efec6a92210d239a018a13406319ae03 107 Hamap MF_00725 Flagellar transcriptional regulator FlhD [flhD]. 3 106 27.56 T 14-10-2018 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 LH59_11295 efec6a92210d239a018a13406319ae03 107 ProDom PD015582 ACTIVATOR TRANSCRIPTIONAL TRANSCRIPTION FLAGELLUM FLHD FLAGELLAR DNA-BINDING REGULATION REGULATOR PROBABLE 12 99 4.0E-43 T 14-10-2018 IPR023559 Flagellar transcriptional activator FlhD GO:0044780|GO:0045893 LH59_09910 d149214f588cc09b8ed59ba2a9a12783 148 Pfam PF13994 PgaD-like protein 1 132 4.8E-29 T 14-10-2018 IPR023829 Poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD GO:0043709 LH59_09910 d149214f588cc09b8ed59ba2a9a12783 148 TIGRFAM TIGR03940 PGA_PgaD: poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD 2 136 3.7E-24 T 14-10-2018 IPR023829 Poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD GO:0043709 LH59_09910 d149214f588cc09b8ed59ba2a9a12783 148 ProDom PD460230 MEMBRANE STORAGE INNER HAEMIN SYSTEM HMSS PGA BIOFILM PGAD TRANSMEMBRANE 1 132 2.0E-4 T 14-10-2018 LH59_01050 6b7b940e35bedc9413d83022b1c19ebd 256 Pfam PF03746 LamB/YcsF family 6 244 2.1E-90 T 14-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 LH59_01050 6b7b940e35bedc9413d83022b1c19ebd 256 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 4 248 41.33 T 14-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 LH59_01050 6b7b940e35bedc9413d83022b1c19ebd 256 SUPERFAMILY SSF88713 5 252 8.15E-90 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 LH59_01050 6b7b940e35bedc9413d83022b1c19ebd 256 Gene3D G3DSA:3.20.20.370 4 255 1.1E-92 T 14-10-2018 LH59_18460 0a86e6068a536267454e66b12612847f 316 SUPERFAMILY SSF51556 3 312 5.3E-85 T 14-10-2018 IPR032466 Metal-dependent hydrolase LH59_18460 0a86e6068a536267454e66b12612847f 316 Gene3D G3DSA:3.20.20.140 2 316 5.0E-101 T 14-10-2018 LH59_18460 0a86e6068a536267454e66b12612847f 316 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 8 312 6.2E-107 T 14-10-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 LH59_18460 0a86e6068a536267454e66b12612847f 316 Hamap MF_01962 Adenine deaminase. 4 316 82.6 T 14-10-2018 IPR028892 Adenine deaminase type 2 GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 LH59_18460 0a86e6068a536267454e66b12612847f 316 Pfam PF00962 Adenosine/AMP deaminase 8 311 3.6E-71 T 14-10-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 LH59_11065 3ee615fad5e15ebc9d2cb2864489738a 195 Pfam PF04612 Type II secretion system (T2SS), protein M 24 186 9.6E-25 T 14-10-2018 IPR007690 Type II secretion system, protein M GO:0009306 LH59_24830 92a2135927447ddd44fe78a9ae35e402 297 Pfam PF02535 ZIP Zinc transporter 147 292 6.3E-22 T 14-10-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 LH59_08935 97f8ab42eaa74cc3d4cf6e9806ad9338 293 Pfam PF13557 Putative MetA-pathway of phenol degradation 61 289 9.0E-25 T 14-10-2018 IPR025737 MetA-pathway of phenol degradation, putative LH59_20630 e6dc623dcf6344317b2bb4386c23727b 255 Pfam PF08861 Domain of unknown function DUF1828 30 111 7.5E-5 T 14-10-2018 IPR014960 Domain of unknown function DUF1828 LH59_03010 bbc388ecc63734f6ba6225b33a289b14 247 SUPERFAMILY SSF53955 110 246 1.03E-42 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily LH59_03010 bbc388ecc63734f6ba6225b33a289b14 247 Gene3D G3DSA:1.10.530.10 114 247 3.7E-43 T 14-10-2018 LH59_03010 bbc388ecc63734f6ba6225b33a289b14 247 Pfam PF01464 Transglycosylase SLT domain 120 223 5.2E-28 T 14-10-2018 IPR008258 Transglycosylase SLT domain 1 LH59_03850 e40ae19a16b5600287125e804a081b25 507 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 22 441 7.4E-133 T 14-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane LH59_09335 2153deb09fe6714a4c8a2fe7b451a6cd 123 Pfam PF09842 Predicted membrane protein (DUF2069) 13 114 9.0E-34 T 14-10-2018 IPR018643 Protein of unknown function DUF2069, membrane LH59_18420 081aa2086f4b940dcca8c56df349dcfe 579 SUPERFAMILY SSF53187 322 464 8.27E-18 T 14-10-2018 LH59_18420 081aa2086f4b940dcca8c56df349dcfe 579 Gene3D G3DSA:3.40.630.10 319 577 5.2E-20 T 14-10-2018 LH59_05630 115b9b80890c3ba9bb07cac6f3d70099 256 Hamap MF_00652 UPF0246 protein YaaA [yaaA]. 1 255 34.888 T 14-10-2018 IPR005583 Peroxide stress protein YaaA LH59_05630 115b9b80890c3ba9bb07cac6f3d70099 256 Pfam PF03883 Peroxide stress protein YaaA 1 243 4.0E-90 T 14-10-2018 IPR005583 Peroxide stress protein YaaA LH59_10545 315bcccef6e083c83803933640a66abe 284 Pfam PF05853 beta-keto acid cleavage enzyme 15 281 1.5E-69 T 14-10-2018 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00310+2.3.1.247 LH59_10545 315bcccef6e083c83803933640a66abe 284 SUPERFAMILY SSF51604 37 174 9.53E-5 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily LH59_10545 315bcccef6e083c83803933640a66abe 284 Gene3D G3DSA:3.20.20.70 9 283 1.2E-74 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_17985 b89f1d6ee63a351b649188e9a421386e 323 Pfam PF16220 Domain of unknown function (DUF4880) 3 42 1.6E-13 T 14-10-2018 IPR032623 FecR, N-terminal LH59_17985 b89f1d6ee63a351b649188e9a421386e 323 PIRSF PIRSF018266 1 321 6.6E-79 T 14-10-2018 IPR012373 Fe(2+)-dicitrate sensor, transmembrane component LH59_17985 b89f1d6ee63a351b649188e9a421386e 323 Pfam PF04773 FecR protein 119 209 4.4E-18 T 14-10-2018 IPR006860 FecR protein LH59_17985 b89f1d6ee63a351b649188e9a421386e 323 Gene3D G3DSA:2.60.120.1440 109 239 7.7E-19 T 14-10-2018 LH59_13225 a139bd8f243d8f138be33a824ee266e4 692 Pfam PF13515 Fusaric acid resistance protein-like 393 518 2.3E-18 T 14-10-2018 LH59_13225 a139bd8f243d8f138be33a824ee266e4 692 Pfam PF12805 FUSC-like inner membrane protein yccS 58 239 1.5E-8 T 14-10-2018 IPR032692 Integral membrane protein YccS, N-terminal LH59_21435 21f7dc225a57781eb78d77a9e4c05261 333 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 35 312 1.5E-60 T 14-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 LH59_21435 21f7dc225a57781eb78d77a9e4c05261 333 Gene3D G3DSA:3.40.190.100 119 247 3.3E-48 T 14-10-2018 LH59_21435 21f7dc225a57781eb78d77a9e4c05261 333 SUPERFAMILY SSF53850 32 328 2.44E-79 T 14-10-2018 LH59_21435 21f7dc225a57781eb78d77a9e4c05261 333 Gene3D G3DSA:3.40.190.10 36 321 3.3E-48 T 14-10-2018 LH59_27160 d58b11bafd12818b1a304cb52a1b08ba 288 SUPERFAMILY SSF81345 12 270 2.62E-22 T 14-10-2018 IPR037294 ABC transporter, BtuC-like LH59_27160 d58b11bafd12818b1a304cb52a1b08ba 288 Pfam PF00950 ABC 3 transport family 14 272 6.1E-51 T 14-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 LH59_01040 3f3a3d52d0912ea5522875999b159def 213 Gene3D G3DSA:2.40.160.20 30 213 8.6E-66 T 14-10-2018 LH59_01040 3f3a3d52d0912ea5522875999b159def 213 SUPERFAMILY SSF56925 33 213 1.33E-27 T 14-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel LH59_01040 3f3a3d52d0912ea5522875999b159def 213 Pfam PF03922 OmpW family 31 213 2.5E-52 T 14-10-2018 IPR005618 Outer membrane protein, OmpW GO:0019867 LH59_09865 e3fa97ba72d154be51645c5b51f5b869 128 SUPERFAMILY SSF50022 9 115 8.9E-22 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 LH59_09865 e3fa97ba72d154be51645c5b51f5b869 128 Gene3D G3DSA:2.102.10.10 8 123 1.4E-12 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 LH59_09865 e3fa97ba72d154be51645c5b51f5b869 128 Pfam PF00355 Rieske [2Fe-2S] domain 11 98 2.9E-7 T 14-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 LH59_04860 45eb5ecf719b55491cacee0433182b1f 163 SUPERFAMILY SSF54427 7 163 7.37E-42 T 14-10-2018 IPR032710 NTF2-like domain superfamily LH59_04860 45eb5ecf719b55491cacee0433182b1f 163 Pfam PF00866 Ring hydroxylating beta subunit 15 151 5.0E-26 T 14-10-2018 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0006725|GO:0055114 LH59_04860 45eb5ecf719b55491cacee0433182b1f 163 Gene3D G3DSA:3.10.450.50 4 163 3.8E-42 T 14-10-2018 LH59_10480 4fce9b2c430defeba8d32192d3c254cb 153 Pfam PF03918 Cytochrome C biogenesis protein 14 148 3.1E-47 T 14-10-2018 IPR005616 CcmH/CycL/Ccl2/NrfF family LH59_10480 4fce9b2c430defeba8d32192d3c254cb 153 Gene3D G3DSA:1.10.8.640 22 102 1.2E-30 T 14-10-2018 IPR038297 CcmH/CycL/Ccl2/NrfF domain superfamily LH59_01900 ae7af08c03738e6de058a89d250339b6 300 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 286 1.6E-54 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_01900 ae7af08c03738e6de058a89d250339b6 300 TIGRFAM TIGR03409 urea_trans_UrtB: urea ABC transporter, permease protein UrtB 8 299 6.8E-123 T 14-10-2018 IPR017779 ABC transporter, urea permease protein UrtB, bacterial-type LH59_26750 948d80dc59f3aba501896ab26566a35f 189 PIRSF PIRSF018472 25 183 3.0E-33 T 14-10-2018 IPR026034 Cell shape-determining protein MreD, proteobacterial type LH59_26750 948d80dc59f3aba501896ab26566a35f 189 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 34 174 1.2E-22 T 14-10-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 LH59_26750 948d80dc59f3aba501896ab26566a35f 189 Pfam PF04093 rod shape-determining protein MreD 48 169 9.1E-13 T 14-10-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 LH59_25825 5fd608c93497d58e18d408b6673d5785 313 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 300 2.8E-32 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_04715 b6971f89424007b4941e0bb13bbc6aa5 217 Pfam PF04752 ChaC-like protein 41 206 3.3E-41 T 14-10-2018 IPR006840 Glutathione-specific gamma-glutamylcyclotransferase GO:0003839|GO:0006751 KEGG: 00480+4.3.2.7|MetaCyc: PWY-7942|Reactome: R-HSA-174403 LH59_04715 b6971f89424007b4941e0bb13bbc6aa5 217 SUPERFAMILY SSF110857 41 155 4.51E-10 T 14-10-2018 IPR036568 Gamma-glutamyl cyclotransferase-like superfamily LH59_04715 b6971f89424007b4941e0bb13bbc6aa5 217 Gene3D G3DSA:3.10.490.10 29 209 2.0E-10 T 14-10-2018 LH59_17240 167625cbe6d6b775dd3de9e09f6d92b1 251 Pfam PF01435 Peptidase family M48 73 246 1.1E-25 T 14-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 LH59_17240 167625cbe6d6b775dd3de9e09f6d92b1 251 Gene3D G3DSA:3.30.2010.10 61 147 6.3E-8 T 14-10-2018 LH59_25355 d6112fd2df769500fcb23dd5dc64e2fc 148 Pfam PF01476 LysM domain 95 145 1.4E-12 T 14-10-2018 IPR018392 LysM domain LH59_25355 d6112fd2df769500fcb23dd5dc64e2fc 148 Gene3D G3DSA:3.10.350.10 93 144 1.6E-14 T 14-10-2018 IPR036779 LysM domain superfamily LH59_25355 d6112fd2df769500fcb23dd5dc64e2fc 148 SUPERFAMILY SSF54106 93 145 8.76E-8 T 14-10-2018 LH59_25355 d6112fd2df769500fcb23dd5dc64e2fc 148 SMART SM00257 94 145 4.7E-10 T 14-10-2018 IPR018392 LysM domain LH59_25355 d6112fd2df769500fcb23dd5dc64e2fc 148 Pfam PF04972 BON domain 27 86 7.4E-12 T 14-10-2018 IPR007055 BON domain LH59_05105 4fbc64eb16b8ef62852f89b9de2b1456 70 Pfam PF10276 Zinc-finger domain 23 58 9.2E-10 T 14-10-2018 IPR019401 Zinc finger, CHCC-type Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_05105 4fbc64eb16b8ef62852f89b9de2b1456 70 Gene3D G3DSA:2.60.260.40 7 61 5.8E-12 T 14-10-2018 LH59_08770 c6ff76e76d1fd459fd9636f6bdac4ce8 323 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 72 315 1.0E-47 T 14-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 LH59_08770 c6ff76e76d1fd459fd9636f6bdac4ce8 323 Gene3D G3DSA:3.40.50.2000 170 322 3.7E-24 T 14-10-2018 LH59_08770 c6ff76e76d1fd459fd9636f6bdac4ce8 323 SUPERFAMILY SSF53756 9 320 3.92E-43 T 14-10-2018 LH59_08770 c6ff76e76d1fd459fd9636f6bdac4ce8 323 Gene3D G3DSA:3.40.50.2000 7 144 2.3E-17 T 14-10-2018 LH59_11770 eda7dd4b25f26dd6a4997ae665d595ed 144 Gene3D G3DSA:3.30.530.20 1 144 2.5E-39 T 14-10-2018 IPR023393 START-like domain superfamily LH59_11770 eda7dd4b25f26dd6a4997ae665d595ed 144 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 134 1.7E-34 T 14-10-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 LH59_11770 eda7dd4b25f26dd6a4997ae665d595ed 144 SUPERFAMILY SSF55961 1 143 1.01E-37 T 14-10-2018 LH59_26235 6b7561929f74deaac46804964db52b65 144 Gene3D G3DSA:3.30.1360.200 23 117 2.5E-6 T 14-10-2018 LH59_20565 ef0b3d5bdcfbfec340a7cbac571d215e 173 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 70 129 7.0E-4 T 14-10-2018 LH59_20565 ef0b3d5bdcfbfec340a7cbac571d215e 173 Pfam PF13827 Domain of unknown function (DUF4189) 72 166 2.1E-18 T 14-10-2018 IPR025240 Domain of unknown function DUF4189 LH59_11220 106bfd29db477ffb8bd0269fdea391b7 176 SUPERFAMILY SSF53335 4 129 2.84E-16 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_11220 106bfd29db477ffb8bd0269fdea391b7 176 Gene3D G3DSA:3.40.50.150 1 164 6.9E-17 T 14-10-2018 LH59_00295 8cee7cd8bcee1ee819c4573e4188e5ae 175 Gene3D G3DSA:2.170.270.10 6 172 2.7E-44 T 14-10-2018 LH59_00295 8cee7cd8bcee1ee819c4573e4188e5ae 175 Pfam PF00856 SET domain 21 124 1.6E-18 T 14-10-2018 IPR001214 SET domain GO:0005515 LH59_00295 8cee7cd8bcee1ee819c4573e4188e5ae 175 SUPERFAMILY SSF82199 8 150 1.83E-41 T 14-10-2018 LH59_00295 8cee7cd8bcee1ee819c4573e4188e5ae 175 SMART SM00317 9 130 9.4E-28 T 14-10-2018 IPR001214 SET domain GO:0005515 LH59_09105 5958e144223baed9db10b0b4d23da437 86 SUPERFAMILY SSF54565 1 76 1.22E-27 T 14-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_09105 5958e144223baed9db10b0b4d23da437 86 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 1 78 22.912 T 14-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_09105 5958e144223baed9db10b0b4d23da437 86 Pfam PF00886 Ribosomal protein S16 8 68 8.9E-24 T 14-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_09105 5958e144223baed9db10b0b4d23da437 86 Gene3D G3DSA:3.30.1320.10 1 84 2.7E-29 T 14-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_09105 5958e144223baed9db10b0b4d23da437 86 TIGRFAM TIGR00002 S16: ribosomal protein bS16 2 77 5.5E-27 T 14-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_01925 5d695402ad8ac91f8072ae7c0bb42143 274 Pfam PF08406 CbbQ/NirQ/NorQ C-terminal 188 271 8.9E-30 T 14-10-2018 IPR013615 CbbQ/NirQ/NorQ, C-terminal LH59_01925 5d695402ad8ac91f8072ae7c0bb42143 274 SUPERFAMILY SSF52540 32 230 2.55E-34 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_01925 5d695402ad8ac91f8072ae7c0bb42143 274 Pfam PF07728 AAA domain (dynein-related subfamily) 41 175 2.3E-33 T 14-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 LH59_01925 5d695402ad8ac91f8072ae7c0bb42143 274 Gene3D G3DSA:3.40.50.300 26 193 4.4E-32 T 14-10-2018 LH59_26220 4a2c58f8a77a2991560a88cc1d591de7 263 PIRSF PIRSF006241 1 260 9.9E-96 T 14-10-2018 IPR026040 Hydroxypyruvate isomerase-like LH59_26220 4a2c58f8a77a2991560a88cc1d591de7 263 Pfam PF01261 Xylose isomerase-like TIM barrel 21 218 1.5E-34 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain LH59_26220 4a2c58f8a77a2991560a88cc1d591de7 263 SUPERFAMILY SSF51658 1 258 7.88E-83 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily LH59_26220 4a2c58f8a77a2991560a88cc1d591de7 263 Gene3D G3DSA:3.20.20.150 1 260 2.1E-78 T 14-10-2018 LH59_23265 7f4c63f22d95b35e777c0bbe509534bc 207 Pfam PF03006 Haemolysin-III related 4 197 3.5E-36 T 14-10-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 LH59_23265 7f4c63f22d95b35e777c0bbe509534bc 207 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 5 202 2.0E-52 T 14-10-2018 IPR005744 Hly-III GO:0016021|GO:0019835 LH59_18930 d7a68d96ed0801752055d62bfe683450 640 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 192 300 2.8E-13 T 14-10-2018 LH59_18930 d7a68d96ed0801752055d62bfe683450 640 SUPERFAMILY SSF49899 135 354 5.94E-26 T 14-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily LH59_18930 d7a68d96ed0801752055d62bfe683450 640 Pfam PF10102 Domain of unknown function (DUF2341) 72 153 1.9E-19 T 14-10-2018 IPR018765 Domain of unknown function DUF2341 LH59_18930 d7a68d96ed0801752055d62bfe683450 640 SMART SM00560 202 354 0.0092 T 14-10-2018 IPR006558 LamG-like jellyroll fold LH59_18930 d7a68d96ed0801752055d62bfe683450 640 Pfam PF01618 MotA/TolQ/ExbB proton channel family 481 591 2.3E-26 T 14-10-2018 IPR002898 MotA/TolQ/ExbB proton channel LH59_18930 d7a68d96ed0801752055d62bfe683450 640 Gene3D G3DSA:2.60.120.200 138 352 2.5E-19 T 14-10-2018 LH59_02180 0b44763129ed98ac4443e7f07cfa6832 409 Gene3D G3DSA:3.30.1540.10 246 337 1.2E-146 T 14-10-2018 LH59_02180 0b44763129ed98ac4443e7f07cfa6832 409 SUPERFAMILY SSF89796 2 407 4.71E-144 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily LH59_02180 0b44763129ed98ac4443e7f07cfa6832 409 Gene3D G3DSA:3.40.50.10540 8 404 1.2E-146 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily LH59_02180 0b44763129ed98ac4443e7f07cfa6832 409 Pfam PF02515 CoA-transferase family III 8 386 1.7E-132 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 LH59_07200 1807ec5c022f0c806744faef078d4d97 526 PIRSF PIRSF016636 1 526 5.4E-122 T 14-10-2018 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB LH59_07200 1807ec5c022f0c806744faef078d4d97 526 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 144 301 2.8E-17 T 14-10-2018 IPR004299 Membrane bound O-acyl transferase, MBOAT LH59_07200 1807ec5c022f0c806744faef078d4d97 526 PIRSF PIRSF500217 1 526 6.1E-120 T 14-10-2018 IPR028362 Alginate O-acetyltransferase AlgI GO:0042121 LH59_07485 d7988cad2438193282e627108b8bccd9 94 PIRSF PIRSF030200 1 94 1.8E-42 T 14-10-2018 IPR009359 Phenylacetic acid degradation B LH59_07485 d7988cad2438193282e627108b8bccd9 94 Gene3D G3DSA:3.10.20.520 1 64 2.4E-31 T 14-10-2018 IPR038693 Phenylacetyl-CoA epoxidase, subunit B LH59_07485 d7988cad2438193282e627108b8bccd9 94 TIGRFAM TIGR02157 PA_CoA_Oxy2: phenylacetate-CoA oxygenase, PaaH subunit 5 94 2.5E-42 T 14-10-2018 IPR009359 Phenylacetic acid degradation B LH59_07485 d7988cad2438193282e627108b8bccd9 94 Pfam PF06243 Phenylacetic acid degradation B 4 90 1.1E-38 T 14-10-2018 IPR009359 Phenylacetic acid degradation B LH59_23000 0c07c724280f729f2dfbd7f375e4883e 111 Pfam PF13670 Peptidase propeptide and YPEB domain 36 107 2.7E-11 T 14-10-2018 IPR025711 PepSY domain LH59_17500 5c1d050f792951cea0f8d88853ad8caa 116 Pfam PF02924 Bacteriophage lambda head decoration protein D 4 104 1.8E-26 T 14-10-2018 IPR004195 Head decoration protein D LH59_01155 9739daeb2d787ca17e3854a8aa4d4abe 249 Pfam PF02104 SURF1 family 4 222 8.5E-28 T 14-10-2018 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_00265 0459e13b4da439d87e1721c306e557cf 150 Gene3D G3DSA:3.10.450.50 23 150 2.2E-40 T 14-10-2018 LH59_00265 0459e13b4da439d87e1721c306e557cf 150 Pfam PF12680 SnoaL-like domain 34 132 3.9E-13 T 14-10-2018 IPR037401 SnoaL-like domain LH59_00265 0459e13b4da439d87e1721c306e557cf 150 SUPERFAMILY SSF54427 28 140 1.3E-25 T 14-10-2018 IPR032710 NTF2-like domain superfamily LH59_25955 884058bf2cd4a23206e09a55123acb8a 98 Gene3D G3DSA:3.30.70.1060 1 95 8.5E-26 T 14-10-2018 LH59_25955 884058bf2cd4a23206e09a55123acb8a 98 Pfam PF03795 YCII-related domain 1 88 2.3E-19 T 14-10-2018 IPR005545 YCII-related LH59_25955 884058bf2cd4a23206e09a55123acb8a 98 SUPERFAMILY SSF54909 1 90 5.36E-21 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel LH59_12900 ed3ac0689a80d715273dc3ad33322838 294 Pfam PF06629 MltA-interacting protein MipA 64 293 6.5E-38 T 14-10-2018 IPR010583 MltA-interacting MipA LH59_12365 e4a02d3c64a49364d736f12e3089a68f 286 Gene3D G3DSA:2.70.70.10 154 284 5.2E-35 T 14-10-2018 IPR011055 Duplicated hybrid motif LH59_12365 e4a02d3c64a49364d736f12e3089a68f 286 SUPERFAMILY SSF51261 65 283 7.85E-49 T 14-10-2018 IPR011055 Duplicated hybrid motif LH59_12365 e4a02d3c64a49364d736f12e3089a68f 286 Pfam PF01551 Peptidase family M23 185 279 2.3E-30 T 14-10-2018 IPR016047 Peptidase M23 LH59_12365 e4a02d3c64a49364d736f12e3089a68f 286 Pfam PF01476 LysM domain 65 106 2.0E-15 T 14-10-2018 IPR018392 LysM domain LH59_12365 e4a02d3c64a49364d736f12e3089a68f 286 SMART SM00257 64 108 2.4E-16 T 14-10-2018 IPR018392 LysM domain LH59_12365 e4a02d3c64a49364d736f12e3089a68f 286 Gene3D G3DSA:3.10.350.10 54 113 1.6E-17 T 14-10-2018 IPR036779 LysM domain superfamily LH59_09175 55be1b8ae18c7c51f6fd5c8e2e7ce404 212 Gene3D G3DSA:1.25.40.10 98 203 4.1E-7 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_09175 55be1b8ae18c7c51f6fd5c8e2e7ce404 212 SUPERFAMILY SSF48452 98 190 5.84E-7 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_09175 55be1b8ae18c7c51f6fd5c8e2e7ce404 212 PIRSF PIRSF006170 1 212 3.0E-50 T 14-10-2018 IPR026039 Uncharacterised protein family UPF0070 LH59_09175 55be1b8ae18c7c51f6fd5c8e2e7ce404 212 Pfam PF09976 Tetratricopeptide repeat-like domain 15 210 2.3E-54 T 14-10-2018 IPR018704 Tetratricopeptide repeat-like domain Reactome: R-HSA-192823|Reactome: R-HSA-381038|Reactome: R-HSA-381426|Reactome: R-HSA-6798695|Reactome: R-HSA-8957275 LH59_12010 e9161732a0bf3b93647e894925be10df 646 Pfam PF13515 Fusaric acid resistance protein-like 350 471 2.1E-14 T 14-10-2018 LH59_09425 94ad055f268d8a70ba0f6f1f6b17a827 216 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 196 4.7E-82 T 14-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 LH59_09425 94ad055f268d8a70ba0f6f1f6b17a827 216 Gene3D G3DSA:3.20.19.10 1 188 3.8E-76 T 14-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 LH59_09425 94ad055f268d8a70ba0f6f1f6b17a827 216 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 210 43.235 T 14-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 LH59_09425 94ad055f268d8a70ba0f6f1f6b17a827 216 Pfam PF00694 Aconitase C-terminal domain 1 132 1.2E-37 T 14-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 LH59_09425 94ad055f268d8a70ba0f6f1f6b17a827 216 SUPERFAMILY SSF52016 1 201 2.35E-61 T 14-10-2018 LH59_00040 e48018ce224624b7ed0105c080323f5b 86 Pfam PF07235 Protein of unknown function (DUF1427) 2 84 5.2E-40 T 14-10-2018 IPR009872 Protein of unknown function DUF1427 LH59_00040 e48018ce224624b7ed0105c080323f5b 86 TIGRFAM TIGR03510 XapX: XapX domain 4 48 4.8E-19 T 14-10-2018 IPR020017 XapX domain LH59_16305 99a652f3fad3cb2dd2f0b76cc432682a 623 SUPERFAMILY SSF102114 326 517 1.12E-25 T 14-10-2018 LH59_16305 99a652f3fad3cb2dd2f0b76cc432682a 623 Pfam PF02310 B12 binding domain 194 275 1.1E-6 T 14-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 LH59_16305 99a652f3fad3cb2dd2f0b76cc432682a 623 Gene3D G3DSA:3.80.30.20 347 527 2.3E-12 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe LH59_16305 99a652f3fad3cb2dd2f0b76cc432682a 623 Pfam PF04055 Radical SAM superfamily 352 513 1.3E-10 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 LH59_16305 99a652f3fad3cb2dd2f0b76cc432682a 623 SMART SM00729 349 562 2.3E-14 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 LH59_22510 2093d584dd8294fbc0b61f94ff9d8b4d 491 Pfam PF01384 Phosphate transporter family 30 479 7.4E-84 T 14-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 LH59_12335 d61cab6fa2eae87a7ab8da23a751afda 118 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 10 112 1.4E-8 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain LH59_12335 d61cab6fa2eae87a7ab8da23a751afda 118 Gene3D G3DSA:3.10.180.10 2 117 3.7E-20 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_12335 d61cab6fa2eae87a7ab8da23a751afda 118 SUPERFAMILY SSF54593 8 116 5.1E-24 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_25085 72cfc22a8ac8b012f32e93b7d99ba2d3 367 SUPERFAMILY SSF56281 40 364 1.23E-43 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like LH59_25085 72cfc22a8ac8b012f32e93b7d99ba2d3 367 Pfam PF12706 Beta-lactamase superfamily domain 208 331 2.4E-9 T 14-10-2018 IPR001279 Metallo-beta-lactamase LH59_25085 72cfc22a8ac8b012f32e93b7d99ba2d3 367 SMART SM00849 60 309 0.0011 T 14-10-2018 IPR001279 Metallo-beta-lactamase LH59_25085 72cfc22a8ac8b012f32e93b7d99ba2d3 367 Gene3D G3DSA:3.60.15.10 40 367 2.0E-51 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like LH59_17805 1c9de872b07046538fefb41b140d018e 349 SUPERFAMILY SSF51679 33 336 3.7E-60 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 LH59_17805 1c9de872b07046538fefb41b140d018e 349 Pfam PF00296 Luciferase-like monooxygenase 38 243 5.5E-40 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 LH59_17805 1c9de872b07046538fefb41b140d018e 349 TIGRFAM TIGR03571 lucif_BA3436: luciferase-type oxidoreductase, BA3436 family 26 336 1.2E-114 T 14-10-2018 IPR020020 Luciferase-type oxidoreductase LH59_17805 1c9de872b07046538fefb41b140d018e 349 Gene3D G3DSA:3.20.20.30 16 339 1.5E-93 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 LH59_26480 0543ae235bd090b674e7cc3e5c04a5a0 186 SUPERFAMILY SSF54427 13 139 1.22E-9 T 14-10-2018 IPR032710 NTF2-like domain superfamily LH59_08980 8c15ac94dc1c99e938d98b851570d4a4 1212 TIGRFAM TIGR02099 TIGR02099: TIGR02099 family protein 336 1192 1.8E-225 T 14-10-2018 IPR011836 Conserved hypothetical protein CHP02099 LH59_08980 8c15ac94dc1c99e938d98b851570d4a4 1212 Pfam PF13116 Protein of unknown function 416 695 3.0E-39 T 14-10-2018 IPR025263 Domain of unknown function DUF3971 LH59_08980 8c15ac94dc1c99e938d98b851570d4a4 1212 Pfam PF13502 AsmA-like C-terminal region 950 1185 1.9E-50 T 14-10-2018 IPR032712 AsmA-like, C-terminal LH59_18760 e20cc1b30d96b5ce2d270fd96021adaf 271 Pfam PF01925 Sulfite exporter TauE/SafE 6 268 9.5E-38 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 LH59_09785 3c7201b54ca2208b32ada56298e3c0b6 301 Pfam PF00892 EamA-like transporter family 13 141 1.1E-22 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_09785 3c7201b54ca2208b32ada56298e3c0b6 301 Pfam PF00892 EamA-like transporter family 154 287 5.1E-13 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_09785 3c7201b54ca2208b32ada56298e3c0b6 301 SUPERFAMILY SSF103481 188 293 5.89E-10 T 14-10-2018 LH59_09785 3c7201b54ca2208b32ada56298e3c0b6 301 SUPERFAMILY SSF103481 51 143 8.63E-14 T 14-10-2018 LH59_00960 bcc4f2ceda917dce53b2a009cb84a7c8 363 SUPERFAMILY SSF53383 15 361 6.78E-78 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_00960 bcc4f2ceda917dce53b2a009cb84a7c8 363 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 11 361 55.551 T 14-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 LH59_00960 bcc4f2ceda917dce53b2a009cb84a7c8 363 Gene3D G3DSA:3.90.1150.10 16 356 2.7E-111 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_00960 bcc4f2ceda917dce53b2a009cb84a7c8 363 Pfam PF00155 Aminotransferase class I and II 30 354 1.0E-46 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 LH59_00960 bcc4f2ceda917dce53b2a009cb84a7c8 363 Gene3D G3DSA:3.40.640.10 53 266 2.7E-111 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_00960 bcc4f2ceda917dce53b2a009cb84a7c8 363 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 13 360 1.6E-95 T 14-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 LH59_03210 d243134bdef3e50c548178ff206f88ce 392 Pfam PF04914 DltD protein 73 390 3.4E-57 T 14-10-2018 IPR006998 DltD LH59_28145 0acfa6953be0b5a4d521a55045765e73 508 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 21 445 7.2E-139 T 14-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane LH59_19930 cfafe81dc338964468bc969bdda73ab6 350 Gene3D G3DSA:3.40.50.720 6 281 7.2E-131 T 14-10-2018 LH59_19930 cfafe81dc338964468bc969bdda73ab6 350 Gene3D G3DSA:3.90.25.10 201 336 7.2E-131 T 14-10-2018 LH59_19930 cfafe81dc338964468bc969bdda73ab6 350 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 5 342 2.4E-124 T 14-10-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 LH59_19930 cfafe81dc338964468bc969bdda73ab6 350 Pfam PF16363 GDP-mannose 4,6 dehydratase 7 331 3.8E-53 T 14-10-2018 IPR016040 NAD(P)-binding domain LH59_19930 cfafe81dc338964468bc969bdda73ab6 350 SUPERFAMILY SSF51735 1 344 6.41E-89 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_09005 81c35861a516fbfffad580de21580709 773 SMART SM00434 22 494 1.6E-214 T 14-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 LH59_09005 81c35861a516fbfffad580de21580709 773 TIGRFAM TIGR01062 parC_Gneg: DNA topoisomerase IV, A subunit 22 757 1.2E-230 T 14-10-2018 LH59_09005 81c35861a516fbfffad580de21580709 773 SUPERFAMILY SSF101904 531 722 2.22E-46 T 14-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal LH59_09005 81c35861a516fbfffad580de21580709 773 Gene3D G3DSA:2.120.10.90 530 722 1.1E-25 T 14-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal LH59_09005 81c35861a516fbfffad580de21580709 773 Hamap MF_00936 DNA topoisomerase 4 subunit A [parC]. 15 773 33.255 T 14-10-2018 IPR005742 DNA topoisomerase IV, subunit A, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 LH59_09005 81c35861a516fbfffad580de21580709 773 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 676 714 0.0048 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 LH59_09005 81c35861a516fbfffad580de21580709 773 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 574 616 0.9 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 LH59_09005 81c35861a516fbfffad580de21580709 773 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 628 664 4.0 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 LH59_09005 81c35861a516fbfffad580de21580709 773 Gene3D G3DSA:3.30.1360.40 248 364 2.2E-186 T 14-10-2018 LH59_09005 81c35861a516fbfffad580de21580709 773 Gene3D G3DSA:3.90.199.10 43 516 2.2E-186 T 14-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 LH59_09005 81c35861a516fbfffad580de21580709 773 SUPERFAMILY SSF56719 42 516 8.24E-148 T 14-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 LH59_09005 81c35861a516fbfffad580de21580709 773 Gene3D G3DSA:1.10.268.10 402 487 2.2E-186 T 14-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 LH59_09005 81c35861a516fbfffad580de21580709 773 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 43 500 1.9E-128 T 14-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 LH59_06080 4ec4dba48af33609fa182d3153dd9263 255 Pfam PF01569 PAP2 superfamily 130 243 7.3E-20 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase LH59_06080 4ec4dba48af33609fa182d3153dd9263 255 SUPERFAMILY SSF48317 51 244 5.63E-31 T 14-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily LH59_06080 4ec4dba48af33609fa182d3153dd9263 255 Gene3D G3DSA:1.20.144.10 52 156 4.5E-8 T 14-10-2018 LH59_06080 4ec4dba48af33609fa182d3153dd9263 255 Gene3D G3DSA:1.20.144.10 157 255 4.5E-21 T 14-10-2018 LH59_06080 4ec4dba48af33609fa182d3153dd9263 255 SMART SM00014 126 238 2.5E-12 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase LH59_06925 fec9ce49b640798389bcc605e11ea3a4 150 Pfam PF09980 Predicted membrane protein (DUF2214) 4 149 7.6E-55 T 14-10-2018 IPR018706 Protein of unknown function DUF2214, membrane LH59_13970 b24adf5e2cc3c0c0659c3f7cc470add4 295 Pfam PF05425 Copper resistance protein D 189 289 1.6E-18 T 14-10-2018 IPR008457 Copper resistance protein D GO:0016021 LH59_00350 10efdd52b2c82387a5cd383625400f4f 152 Pfam PF04361 Protein of unknown function (DUF494) 1 152 4.0E-51 T 14-10-2018 IPR007456 Smg LH59_00350 10efdd52b2c82387a5cd383625400f4f 152 Hamap MF_00598 Protein Smg [smg]. 1 152 26.84 T 14-10-2018 IPR007456 Smg LH59_15310 cc8e0d9dc653bde7bcb440c6655cb485 142 SUPERFAMILY SSF55729 1 134 7.77E-30 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_15310 cc8e0d9dc653bde7bcb440c6655cb485 142 Gene3D G3DSA:3.40.630.30 1 138 2.9E-30 T 14-10-2018 LH59_15310 cc8e0d9dc653bde7bcb440c6655cb485 142 Pfam PF00583 Acetyltransferase (GNAT) family 36 129 1.8E-16 T 14-10-2018 IPR000182 GNAT domain LH59_01015 297e3512cd885538a410fb6e4c865b06 278 Gene3D G3DSA:3.40.50.300 11 276 5.3E-65 T 14-10-2018 LH59_01015 297e3512cd885538a410fb6e4c865b06 278 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 LH59_01015 297e3512cd885538a410fb6e4c865b06 278 Pfam PF00005 ABC transporter 28 177 6.5E-30 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 LH59_01015 297e3512cd885538a410fb6e4c865b06 278 SMART SM00382 37 225 5.2E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_01015 297e3512cd885538a410fb6e4c865b06 278 SUPERFAMILY SSF52540 13 245 3.51E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_04785 3488c181c7efbf4eca6f2f3d12f5c4e4 263 Pfam PF01614 Bacterial transcriptional regulator 129 239 7.2E-24 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal LH59_04785 3488c181c7efbf4eca6f2f3d12f5c4e4 263 Gene3D G3DSA:1.10.10.10 5 81 4.6E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_04785 3488c181c7efbf4eca6f2f3d12f5c4e4 263 SMART SM00346 13 101 2.4E-10 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_04785 3488c181c7efbf4eca6f2f3d12f5c4e4 263 Gene3D G3DSA:3.30.450.40 83 257 9.1E-47 T 14-10-2018 IPR029016 GAF-like domain superfamily LH59_04785 3488c181c7efbf4eca6f2f3d12f5c4e4 263 SUPERFAMILY SSF46785 16 85 2.73E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_04785 3488c181c7efbf4eca6f2f3d12f5c4e4 263 SUPERFAMILY SSF55781 69 255 1.24E-45 T 14-10-2018 LH59_04785 3488c181c7efbf4eca6f2f3d12f5c4e4 263 Pfam PF09339 IclR helix-turn-helix domain 18 63 3.1E-10 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 LH59_21405 82d4dd54c041f79a4877c0e7257c6d98 360 Gene3D G3DSA:2.130.10.10 9 359 6.1E-87 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 LH59_21405 82d4dd54c041f79a4877c0e7257c6d98 360 Pfam PF10282 Lactonase, 7-bladed beta-propeller 15 356 7.5E-79 T 14-10-2018 IPR019405 Lactonase, 7-bladed beta propeller LH59_21405 82d4dd54c041f79a4877c0e7257c6d98 360 SUPERFAMILY SSF51004 40 339 2.41E-32 T 14-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily LH59_12875 bd157df5ed3173df03c45b046de3c8f6 201 Gene3D G3DSA:3.40.50.1820 2 179 3.8E-55 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_12875 bd157df5ed3173df03c45b046de3c8f6 201 SUPERFAMILY SSF53474 6 171 8.51E-37 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_12875 bd157df5ed3173df03c45b046de3c8f6 201 Pfam PF06821 Serine hydrolase 6 171 1.1E-66 T 14-10-2018 IPR010662 Putative hydrolase RBBP9/YdeN GO:0016787 LH59_02270 41ce746f15af8c1507ff585475914d61 328 Pfam PF02653 Branched-chain amino acid transport system / permease component 37 309 1.9E-32 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_05335 df2b7054178bfb6c09853fd181f8372d 199 Pfam PF13302 Acetyltransferase (GNAT) domain 11 151 2.1E-28 T 14-10-2018 IPR000182 GNAT domain LH59_05335 df2b7054178bfb6c09853fd181f8372d 199 Gene3D G3DSA:3.40.630.30 4 162 4.6E-42 T 14-10-2018 LH59_05335 df2b7054178bfb6c09853fd181f8372d 199 SUPERFAMILY SSF55729 5 172 1.2E-35 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_03690 134e6ee7471d945be0e1e1c6f6ddee61 401 Gene3D G3DSA:3.40.50.2300 53 358 2.1E-107 T 14-10-2018 LH59_03690 134e6ee7471d945be0e1e1c6f6ddee61 401 SUPERFAMILY SSF53822 30 379 2.09E-84 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_03690 134e6ee7471d945be0e1e1c6f6ddee61 401 Pfam PF13458 Periplasmic binding protein 30 365 5.3E-84 T 14-10-2018 IPR028081 Leucine-binding protein domain LH59_03690 134e6ee7471d945be0e1e1c6f6ddee61 401 Gene3D G3DSA:3.40.50.2300 149 366 2.1E-107 T 14-10-2018 LH59_12235 c45ce68e15c9b2adaed347aa18d21bde 325 Gene3D G3DSA:3.40.190.10 126 249 4.1E-116 T 14-10-2018 LH59_12235 c45ce68e15c9b2adaed347aa18d21bde 325 SUPERFAMILY SSF53850 113 285 1.01E-10 T 14-10-2018 LH59_12235 c45ce68e15c9b2adaed347aa18d21bde 325 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 321 1.4E-84 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_12235 c45ce68e15c9b2adaed347aa18d21bde 325 Gene3D G3DSA:3.40.190.150 28 310 4.1E-116 T 14-10-2018 LH59_12235 c45ce68e15c9b2adaed347aa18d21bde 325 PIRSF PIRSF017082 1 324 1.0E-87 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 LH59_17740 45f116f04c7149aa4edd94852b801f86 346 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 177 2.7E-29 T 14-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase LH59_08090 a84686b6606cbbcc4b3f6aaba5876acc 231 Gene3D G3DSA:3.90.850.10 1 231 9.6E-84 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 LH59_08090 a84686b6606cbbcc4b3f6aaba5876acc 231 SUPERFAMILY SSF56529 20 231 1.2E-71 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 LH59_08090 a84686b6606cbbcc4b3f6aaba5876acc 231 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 27 230 5.7E-52 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 LH59_19545 badc8442ba8c49a0058898ad0b9eeb5f 284 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 72 276 8.1E-73 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 LH59_19545 badc8442ba8c49a0058898ad0b9eeb5f 284 SUPERFAMILY SSF56529 60 277 2.62E-82 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 LH59_19545 badc8442ba8c49a0058898ad0b9eeb5f 284 Gene3D G3DSA:3.90.850.10 67 282 5.6E-87 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 LH59_06575 db6cb163e8aab5f4de1f56abf12e1acb 365 Gene3D G3DSA:3.40.50.1100 97 198 1.5E-80 T 14-10-2018 LH59_06575 db6cb163e8aab5f4de1f56abf12e1acb 365 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 60 359 2.1E-61 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme LH59_06575 db6cb163e8aab5f4de1f56abf12e1acb 365 SUPERFAMILY SSF53686 57 360 7.2E-59 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme LH59_06575 db6cb163e8aab5f4de1f56abf12e1acb 365 Gene3D G3DSA:3.40.50.1100 57 362 1.5E-80 T 14-10-2018 LH59_06435 29fdbfeb5465ccbb6f63237773bd76fc 182 Pfam PF09411 Lipid A 3-O-deacylase (PagL) 51 180 4.7E-32 T 14-10-2018 IPR018550 Lipid A 3-O-deacylase-related LH59_06435 29fdbfeb5465ccbb6f63237773bd76fc 182 SUPERFAMILY SSF56925 33 182 2.46E-10 T 14-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel LH59_06435 29fdbfeb5465ccbb6f63237773bd76fc 182 Gene3D G3DSA:2.40.160.20 35 181 7.4E-40 T 14-10-2018 LH59_06435 29fdbfeb5465ccbb6f63237773bd76fc 182 PIRSF PIRSF029681 1 182 8.7E-53 T 14-10-2018 IPR018550 Lipid A 3-O-deacylase-related LH59_02125 17fc132ef4f038d0dc0ed6ceb5cf70b8 323 Gene3D G3DSA:3.40.630.10 24 321 3.7E-48 T 14-10-2018 LH59_02125 17fc132ef4f038d0dc0ed6ceb5cf70b8 323 SUPERFAMILY SSF53187 16 321 6.91E-50 T 14-10-2018 LH59_02125 17fc132ef4f038d0dc0ed6ceb5cf70b8 323 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 41 192 3.2E-11 T 14-10-2018 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0016788 LH59_13520 072cbac9b59ee3487866c220ce3e46da 257 Gene3D G3DSA:1.10.3720.10 53 248 4.7E-24 T 14-10-2018 IPR035906 MetI-like superfamily LH59_13520 072cbac9b59ee3487866c220ce3e46da 257 SUPERFAMILY SSF161098 57 241 9.55E-30 T 14-10-2018 IPR035906 MetI-like superfamily LH59_13520 072cbac9b59ee3487866c220ce3e46da 257 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 252 7.0E-21 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_13160 ded0c6852ec23f64973fc554a0cacfa0 94 Pfam PF04070 Domain of unknown function (DUF378) 32 87 1.7E-10 T 14-10-2018 IPR007211 Protein of unknown function DUF378 LH59_00825 87524288224a03b34488cb0c196eaede 402 Pfam PF00266 Aminotransferase class-V 30 390 3.1E-54 T 14-10-2018 IPR000192 Aminotransferase class V domain LH59_00825 87524288224a03b34488cb0c196eaede 402 Gene3D G3DSA:3.40.640.10 36 294 3.5E-94 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 LH59_00825 87524288224a03b34488cb0c196eaede 402 SUPERFAMILY SSF53383 11 397 6.93E-80 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase LH59_00825 87524288224a03b34488cb0c196eaede 402 Gene3D G3DSA:3.90.1150.10 21 391 3.5E-94 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 LH59_00825 87524288224a03b34488cb0c196eaede 402 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 211 231 - T 14-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site LH59_11610 919ef09f749737809ef6d6a2a608436f 162 Pfam PF02674 Colicin V production protein 4 142 7.6E-36 T 14-10-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 LH59_12800 d980efcc74415601ca79ec1209d10bc2 453 Pfam PF07287 Acyclic terpene utilisation family protein AtuA 8 351 7.5E-121 T 14-10-2018 IPR010839 Acyclic terpene utilisation LH59_07145 b3946d636475e8c5810d0896b5f692cd 156 Pfam PF08909 Domain of unknown function (DUF1854) 26 155 2.9E-51 T 14-10-2018 IPR015005 Domain of unknown function DUF1854 LH59_08525 b7287c9a262809f2fbac975632324d48 159 Gene3D G3DSA:3.30.420.270 62 133 1.1E-11 T 14-10-2018 LH59_08525 b7287c9a262809f2fbac975632324d48 159 Pfam PF02472 Biopolymer transport protein ExbD/TolR 16 137 7.0E-32 T 14-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 LH59_03070 19ddf837f79abec6fa6cf3617dadf7e4 224 SUPERFAMILY SSF89562 30 181 1.29E-42 T 14-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily LH59_03070 19ddf837f79abec6fa6cf3617dadf7e4 224 Gene3D G3DSA:3.50.30.40 24 196 2.2E-49 T 14-10-2018 LH59_03070 19ddf837f79abec6fa6cf3617dadf7e4 224 Pfam PF03737 Aldolase/RraA 30 176 1.1E-43 T 14-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein LH59_11750 53687963b136183724fd045f984b8801 146 Pfam PF01957 NfeD-like C-terminal, partner-binding 3 138 2.2E-6 T 14-10-2018 IPR002810 NfeD-like, C-terminal domain LH59_14000 c63b20a52d0c26f3ca73239e0ab984c3 524 Gene3D G3DSA:3.90.1210.30 10 87 9.3E-24 T 14-10-2018 LH59_14000 c63b20a52d0c26f3ca73239e0ab984c3 524 SMART SM00858 18 88 1.1E-8 T 14-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 LH59_14000 c63b20a52d0c26f3ca73239e0ab984c3 524 TIGRFAM TIGR03248 galactar-dH20: galactarate dehydratase 11 524 5.6E-274 T 14-10-2018 IPR017654 Galactarate dehydratase GarD-like GO:0008867|GO:0046392 KEGG: 00053+4.2.1.42|MetaCyc: PWY-6497 LH59_14000 c63b20a52d0c26f3ca73239e0ab984c3 524 Pfam PF08666 SAF domain 18 84 1.1E-8 T 14-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 LH59_14000 c63b20a52d0c26f3ca73239e0ab984c3 524 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 115 522 2.0E-146 T 14-10-2018 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 LH59_24480 a0781f9a518d40597f0d44fa92f8fdc6 128 Pfam PF03476 MOSC N-terminal beta barrel domain 22 110 1.3E-10 T 14-10-2018 IPR005303 MOSC, N-terminal beta barrel KEGG: 00790+2.8.1.9|MetaCyc: PWY-5963 LH59_24480 a0781f9a518d40597f0d44fa92f8fdc6 128 SUPERFAMILY SSF141673 5 125 1.2E-28 T 14-10-2018 LH59_26055 b7f2c6bb0e95e712e8c02063c0e866d2 63 Pfam PF11174 Protein of unknown function (DUF2970) 4 59 5.0E-22 T 14-10-2018 IPR021344 Protein of unknown function DUF2970 LH59_25590 d87ff9590fc1e48a24ca70e319da5851 201 Pfam PF06805 Bacteriophage lambda tail assembly protein I 5 89 8.3E-10 T 14-10-2018 IPR010654 Bacteriophage lambda tail assembly I LH59_26940 3a1aacbebaaaddd824e3877ea7f34d7c 133 Pfam PF04343 Protein of unknown function, DUF488 8 117 5.9E-30 T 14-10-2018 IPR007438 Protein of unknown function DUF488 LH59_12915 32309b6c52a7cbc1becd58110acf21e2 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 292 7.4E-18 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_12915 32309b6c52a7cbc1becd58110acf21e2 293 Gene3D G3DSA:1.10.3720.10 51 292 3.0E-59 T 14-10-2018 IPR035906 MetI-like superfamily LH59_12915 32309b6c52a7cbc1becd58110acf21e2 293 SUPERFAMILY SSF161098 55 281 3.66E-51 T 14-10-2018 IPR035906 MetI-like superfamily LH59_24725 898d7a0cfb62e5be5843f4a4b94f46b1 367 Pfam PF00953 Glycosyl transferase family 4 76 230 1.2E-27 T 14-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 LH59_03365 fa40dbb094693c4597e4317402b8a139 142 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 141 28.809 T 14-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 LH59_03365 fa40dbb094693c4597e4317402b8a139 142 PIRSF PIRSF002181 1 142 2.3E-48 T 14-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 LH59_03365 fa40dbb094693c4597e4317402b8a139 142 Pfam PF00572 Ribosomal protein L13 15 138 1.6E-55 T 14-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 LH59_03365 fa40dbb094693c4597e4317402b8a139 142 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 4 142 3.2E-62 T 14-10-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 LH59_03365 fa40dbb094693c4597e4317402b8a139 142 SUPERFAMILY SSF52161 1 139 2.35E-59 T 14-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 LH59_03365 fa40dbb094693c4597e4317402b8a139 142 Gene3D G3DSA:3.90.1180.10 1 142 3.3E-62 T 14-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 LH59_21705 15518c0147658537dfef7987eee229b7 263 Gene3D G3DSA:1.10.3720.10 1 261 1.4E-44 T 14-10-2018 IPR035906 MetI-like superfamily LH59_21705 15518c0147658537dfef7987eee229b7 263 SUPERFAMILY SSF161098 3 249 7.1E-48 T 14-10-2018 IPR035906 MetI-like superfamily LH59_21705 15518c0147658537dfef7987eee229b7 263 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 247 1.1E-12 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_14805 c19590c0cf32b460edb759604492d518 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 266 2.9E-26 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_14805 c19590c0cf32b460edb759604492d518 275 Gene3D G3DSA:1.10.3720.10 72 267 5.9E-28 T 14-10-2018 IPR035906 MetI-like superfamily LH59_14805 c19590c0cf32b460edb759604492d518 275 SUPERFAMILY SSF161098 75 261 2.75E-35 T 14-10-2018 IPR035906 MetI-like superfamily LH59_07015 74129dbba1bb1568a5c766dc69a82cc5 570 Pfam PF03929 PepSY-associated TM region 20 374 7.5E-67 T 14-10-2018 IPR005625 PepSY-associated TM protein LH59_20820 caea0216dd887e6c800b12a7a8a31e3e 290 Gene3D G3DSA:3.40.50.720 1 163 1.0E-46 T 14-10-2018 LH59_20820 caea0216dd887e6c800b12a7a8a31e3e 290 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 166 284 7.0E-17 T 14-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 LH59_20820 caea0216dd887e6c800b12a7a8a31e3e 290 SUPERFAMILY SSF48179 164 289 9.52E-27 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 LH59_20820 caea0216dd887e6c800b12a7a8a31e3e 290 Gene3D G3DSA:1.10.1040.10 164 290 5.6E-24 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 LH59_20820 caea0216dd887e6c800b12a7a8a31e3e 290 SUPERFAMILY SSF51735 1 163 1.18E-37 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_20820 caea0216dd887e6c800b12a7a8a31e3e 290 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 163 2.3E-37 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 LH59_20820 caea0216dd887e6c800b12a7a8a31e3e 290 PIRSF PIRSF000103 1 290 5.4E-77 T 14-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 LH59_05540 a02e5cdb5da57c89ffec5db7ba13ac57 166 Pfam PF04266 ASCH domain 6 115 1.0E-4 T 14-10-2018 IPR007374 ASCH domain LH59_26950 fed8599f96f645a541d56fc74cb4ba8d 391 SUPERFAMILY SSF52096 47 185 2.49E-6 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily LH59_14985 146ced8d98b1790ec390685008763155 350 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 9 75 1.0E-13 T 14-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 LH59_14985 146ced8d98b1790ec390685008763155 350 Gene3D G3DSA:3.30.450.20 127 251 6.6E-7 T 14-10-2018 LH59_14985 146ced8d98b1790ec390685008763155 350 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 25 52 2.6E-8 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_14985 146ced8d98b1790ec390685008763155 350 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 54 83 2.6E-8 T 14-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 LH59_14985 146ced8d98b1790ec390685008763155 350 SUPERFAMILY SSF58104 6 79 4.71E-18 T 14-10-2018 LH59_14985 146ced8d98b1790ec390685008763155 350 Gene3D G3DSA:1.10.287.950 1 124 2.9E-19 T 14-10-2018 LH59_20815 7e0cf9ba6542ae96df94e128c0823332 235 SUPERFAMILY SSF56529 24 235 2.49E-65 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 LH59_20815 7e0cf9ba6542ae96df94e128c0823332 235 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 29 234 8.8E-48 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 LH59_20815 7e0cf9ba6542ae96df94e128c0823332 235 Gene3D G3DSA:3.90.850.10 3 235 7.3E-78 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 LH59_02840 780520a9cf1be319dbc37a2fc757b5bb 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 285 7.0E-15 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_02840 780520a9cf1be319dbc37a2fc757b5bb 299 SUPERFAMILY SSF161098 13 286 1.96E-57 T 14-10-2018 IPR035906 MetI-like superfamily LH59_02840 780520a9cf1be319dbc37a2fc757b5bb 299 Gene3D G3DSA:1.10.3720.10 10 283 6.6E-53 T 14-10-2018 IPR035906 MetI-like superfamily LH59_23395 23c7b6975ce662854a5487e9a10211bc 295 SUPERFAMILY SSF103481 40 142 5.75E-14 T 14-10-2018 LH59_23395 23c7b6975ce662854a5487e9a10211bc 295 Pfam PF00892 EamA-like transporter family 6 138 3.8E-20 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_23395 23c7b6975ce662854a5487e9a10211bc 295 Pfam PF00892 EamA-like transporter family 151 284 4.1E-20 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_23395 23c7b6975ce662854a5487e9a10211bc 295 SUPERFAMILY SSF103481 186 288 2.09E-14 T 14-10-2018 LH59_03730 b6f82fdf015c4ae1fd1fd00d400460d9 214 Pfam PF01810 LysE type translocator 30 202 4.8E-17 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 LH59_20970 60d5129606acc5ab2bd0fba2f68087ef 129 SUPERFAMILY SSF82784 12 122 6.28E-17 T 14-10-2018 IPR036102 OsmC/Ohr superfamily LH59_20970 60d5129606acc5ab2bd0fba2f68087ef 129 Pfam PF02566 OsmC-like protein 32 121 2.8E-12 T 14-10-2018 IPR003718 OsmC/Ohr family LH59_20970 60d5129606acc5ab2bd0fba2f68087ef 129 Gene3D G3DSA:3.30.300.20 2 115 1.1E-13 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta LH59_23730 f54e649940a2b4188b0b333dfb6eba07 261 Pfam PF02104 SURF1 family 32 241 3.0E-41 T 14-10-2018 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_19840 3e63d948007418671d2e5c2f2b4f0ec8 276 Pfam PF03707 Bacterial signalling protein N terminal repeat 60 117 2.6E-17 T 14-10-2018 IPR005330 MHYT domain LH59_19840 3e63d948007418671d2e5c2f2b4f0ec8 276 Pfam PF03707 Bacterial signalling protein N terminal repeat 123 181 4.4E-15 T 14-10-2018 IPR005330 MHYT domain LH59_20435 18b7c95d017f32588ecdd3b55b992576 505 PIRSF PIRSF028099 2 505 5.1E-178 T 14-10-2018 IPR010538 Di-haem oxidoreductase, putative peroxidase LH59_20435 18b7c95d017f32588ecdd3b55b992576 505 SUPERFAMILY SSF46626 363 505 1.42E-28 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_20435 18b7c95d017f32588ecdd3b55b992576 505 Gene3D G3DSA:1.10.760.10 353 505 2.1E-12 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_20435 18b7c95d017f32588ecdd3b55b992576 505 Pfam PF06537 Di-haem oxidoreductase, putative peroxidase 56 505 2.5E-132 T 14-10-2018 IPR010538 Di-haem oxidoreductase, putative peroxidase LH59_23205 a07195d20d6e9842e4f958a699a0985a 155 Pfam PF05425 Copper resistance protein D 47 154 1.9E-13 T 14-10-2018 IPR008457 Copper resistance protein D GO:0016021 LH59_14930 748dd6a2e51b4b1577332a4326e19fed 683 Pfam PF04632 Fusaric acid resistance protein family 10 670 2.1E-192 T 14-10-2018 IPR006726 Para-hydroxybenzoic acid efflux pump subunit AaeB/fusaric acid resistance protein GO:0005886|GO:0022857|GO:0055085 LH59_06770 d0436000ff1b575ee3266238ec2666a8 364 Pfam PF03576 Peptidase family S58 20 344 3.4E-109 T 14-10-2018 IPR005321 Peptidase S58, DmpA LH59_06770 d0436000ff1b575ee3266238ec2666a8 364 SUPERFAMILY SSF56266 12 359 3.92E-98 T 14-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 LH59_06770 d0436000ff1b575ee3266238ec2666a8 364 Gene3D G3DSA:3.60.70.12 8 353 6.6E-122 T 14-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 LH59_25965 bc5d7b7744a92c0906d05f125f332871 346 SUPERFAMILY SSF102198 95 345 1.26E-14 T 14-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 LH59_25965 bc5d7b7744a92c0906d05f125f332871 346 Pfam PF04199 Putative cyclase 89 274 6.6E-16 T 14-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 LH59_13205 19196b7d873bd54c975571b6e5c462b2 50 Pfam PF11752 Protein of unknown function (DUF3309) 2 50 3.8E-24 T 14-10-2018 IPR021738 Protein of unknown function DUF3309 LH59_13445 f94f13c969ba1e66dbe69d030d58d6f1 159 SUPERFAMILY SSF54427 7 159 4.13E-78 T 14-10-2018 IPR032710 NTF2-like domain superfamily LH59_13445 f94f13c969ba1e66dbe69d030d58d6f1 159 Gene3D G3DSA:3.10.450.50 15 159 1.6E-75 T 14-10-2018 LH59_13445 f94f13c969ba1e66dbe69d030d58d6f1 159 Pfam PF07080 Protein of unknown function (DUF1348) 12 141 2.8E-63 T 14-10-2018 IPR009783 Protein of unknown function DUF1348 LH59_16925 ff3250760a9381a523a64b9cb4e02618 630 Pfam PF03929 PepSY-associated TM region 10 376 6.5E-62 T 14-10-2018 IPR005625 PepSY-associated TM protein LH59_00420 aa6cac06a2bb7f69bd1b6f91bda89143 85 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 2 79 2.6E-26 T 14-10-2018 IPR023845 Domain of unknown function DUF3817, transmembrane LH59_00420 aa6cac06a2bb7f69bd1b6f91bda89143 85 Pfam PF12823 Domain of unknown function (DUF3817) 2 81 2.7E-20 T 14-10-2018 IPR023845 Domain of unknown function DUF3817, transmembrane LH59_10875 d973b0bd420f8714e88f70118dee8bd8 463 Pfam PF07007 Lysozyme inhibitor LprI 31 105 1.4E-6 T 14-10-2018 IPR009739 Lysozyme inhibitor LprI, N-terminal LH59_26810 ce229cb36495bd04e8f836a0fda85c88 210 Pfam PF01810 LysE type translocator 24 208 7.5E-33 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 LH59_27230 3ea468d07f3ee019c810b29ab715ec02 90 Hamap MF_00659 UPF0250 protein YbeD [ybeD]. 2 90 20.885 T 14-10-2018 IPR007454 Uncharacterised protein family UPF0250 LH59_27230 3ea468d07f3ee019c810b29ab715ec02 90 SUPERFAMILY SSF117991 6 90 2.62E-26 T 14-10-2018 IPR027471 YbeD-like domain superfamily LH59_27230 3ea468d07f3ee019c810b29ab715ec02 90 Gene3D G3DSA:3.30.70.260 5 90 2.2E-29 T 14-10-2018 LH59_27230 3ea468d07f3ee019c810b29ab715ec02 90 Pfam PF04359 Protein of unknown function (DUF493) 7 90 4.3E-29 T 14-10-2018 IPR007454 Uncharacterised protein family UPF0250 LH59_10105 0f6bde56bc82a765878245df071dd51b 152 Gene3D G3DSA:1.10.10.10 2 152 7.4E-43 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_10105 0f6bde56bc82a765878245df071dd51b 152 SUPERFAMILY SSF46785 7 144 1.54E-38 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_10105 0f6bde56bc82a765878245df071dd51b 152 Pfam PF01638 HxlR-like helix-turn-helix 21 104 2.1E-18 T 14-10-2018 IPR002577 Helix-turn-helix, HxlR type LH59_08130 c385c74fcbc525a37b43091000b9d3be 73 Gene3D G3DSA:2.30.30.100 20 73 2.2E-18 T 14-10-2018 LH59_08130 c385c74fcbc525a37b43091000b9d3be 73 Pfam PF06004 Bacterial protein of unknown function (DUF903) 24 71 1.8E-17 T 14-10-2018 IPR010305 Protein of unknown function DUF903 LH59_08130 c385c74fcbc525a37b43091000b9d3be 73 SUPERFAMILY SSF50182 22 72 2.45E-13 T 14-10-2018 IPR010920 LSM domain superfamily LH59_02490 e44c89abf7dfe1bdba3e73621df49308 333 SUPERFAMILY SSF54427 208 328 2.01E-15 T 14-10-2018 IPR032710 NTF2-like domain superfamily LH59_02490 e44c89abf7dfe1bdba3e73621df49308 333 Pfam PF04280 Tim44-like domain 208 326 1.6E-12 T 14-10-2018 IPR007379 Tim44-like domain LH59_02490 e44c89abf7dfe1bdba3e73621df49308 333 SMART SM00978 199 326 5.0E-34 T 14-10-2018 IPR007379 Tim44-like domain LH59_26550 49c42efb995240512b45978778814292 174 Pfam PF09335 SNARE associated Golgi protein 56 160 1.9E-11 T 14-10-2018 IPR032816 SNARE associated Golgi protein LH59_25960 18f369f75cd3624314273af8fb5f4a80 259 Pfam PF00561 alpha/beta hydrolase fold 22 245 1.7E-24 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_25960 18f369f75cd3624314273af8fb5f4a80 259 Gene3D G3DSA:3.40.50.1820 1 258 1.4E-72 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_25960 18f369f75cd3624314273af8fb5f4a80 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 2.0E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_25960 18f369f75cd3624314273af8fb5f4a80 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 105 118 2.0E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_25960 18f369f75cd3624314273af8fb5f4a80 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 91 104 2.0E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 LH59_25960 18f369f75cd3624314273af8fb5f4a80 259 TIGRFAM TIGR02427 protocat_pcaD: 3-oxoadipate enol-lactonase 10 258 7.6E-92 T 14-10-2018 IPR026968 3-oxoadipate enol-lactonase 1/2 GO:0042952|GO:0047570 KEGG: 00362+3.1.1.24|MetaCyc: PWY-6185 LH59_25960 18f369f75cd3624314273af8fb5f4a80 259 SUPERFAMILY SSF53474 1 258 4.72E-68 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold LH59_01360 053d2701957a8a13d586e5007c194b37 466 Gene3D G3DSA:1.20.1730.10 10 464 1.8E-73 T 14-10-2018 IPR038377 Sodium/glucose symporter superfamily LH59_01360 053d2701957a8a13d586e5007c194b37 466 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 395 415 - T 14-10-2018 IPR018212 Sodium/solute symporter, conserved site LH59_01360 053d2701957a8a13d586e5007c194b37 466 Pfam PF00474 Sodium:solute symporter family 32 413 6.1E-35 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 LH59_04980 b7fcfaf039802dcde4d2bbc3933a0494 351 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 20 334 7.1E-60 T 14-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 LH59_19530 adda0a54076aab3f92c71aeb9e2552e3 289 SUPERFAMILY SSF56091 15 244 2.22E-40 T 14-10-2018 LH59_19530 adda0a54076aab3f92c71aeb9e2552e3 289 Gene3D G3DSA:3.30.470.30 37 204 3.3E-18 T 14-10-2018 LH59_19530 adda0a54076aab3f92c71aeb9e2552e3 289 Pfam PF09414 RNA ligase 48 230 2.6E-30 T 14-10-2018 IPR021122 RNA ligase domain, REL/Rln2 LH59_11210 518cd0d80820fcdd8bea123782e382f1 83 Pfam PF04226 Transglycosylase associated protein 33 79 2.0E-16 T 14-10-2018 IPR007341 Transglycosylase-associated protein GO:0016021 LH59_04700 7fcfaf3d6dd430df01279835a40b38bf 377 Gene3D G3DSA:3.30.9.10 87 322 2.4E-151 T 14-10-2018 LH59_04700 7fcfaf3d6dd430df01279835a40b38bf 377 Pfam PF01266 FAD dependent oxidoreductase 6 363 4.1E-65 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 LH59_04700 7fcfaf3d6dd430df01279835a40b38bf 377 SUPERFAMILY SSF51905 5 322 3.71E-42 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_04700 7fcfaf3d6dd430df01279835a40b38bf 377 Gene3D G3DSA:3.50.50.60 6 361 2.4E-151 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_27320 ea9a2aa0bf95524e2d234308d0a5e764 197 Pfam PF02397 Bacterial sugar transferase 2 195 6.6E-59 T 14-10-2018 IPR003362 Bacterial sugar transferase LH59_05800 7eb849677172ddeee185711ec42d8b82 242 Pfam PF03724 META domain 15 129 6.3E-16 T 14-10-2018 IPR005184 Domain of unknown function DUF306, Meta/HslJ LH59_05800 7eb849677172ddeee185711ec42d8b82 242 Pfam PF14302 Domain of unknown function (DUF4377) 149 235 5.4E-22 T 14-10-2018 IPR025485 Domain of unknown function DUF4377 LH59_05800 7eb849677172ddeee185711ec42d8b82 242 Gene3D G3DSA:2.40.128.270 11 132 2.0E-15 T 14-10-2018 IPR038670 HslJ-like superfamily LH59_21820 08c2e0ac382a153c15092e3511d0c5d7 83 Pfam PF13991 BssS protein family 14 74 3.2E-10 T 14-10-2018 IPR025730 Biofilm regulator BssS LH59_11555 96f38b30bc7bf43c51be9881d64b9f34 117 Gene3D G3DSA:1.20.58.380 9 97 6.6E-31 T 14-10-2018 LH59_11555 96f38b30bc7bf43c51be9881d64b9f34 117 Pfam PF05400 Flagellar protein FliT 25 110 2.8E-21 T 14-10-2018 IPR008622 Flagellar protein FliT LH59_03185 71c324c36216644aac540b566e8667c8 308 SUPERFAMILY SSF53335 90 303 2.03E-30 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_03185 71c324c36216644aac540b566e8667c8 308 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 3 307 5.6E-82 T 14-10-2018 LH59_03185 71c324c36216644aac540b566e8667c8 308 Gene3D G3DSA:3.40.50.150 109 308 2.6E-54 T 14-10-2018 LH59_03185 71c324c36216644aac540b566e8667c8 308 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 3 301 6.7E-63 T 14-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 LH59_03185 71c324c36216644aac540b566e8667c8 308 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 1 307 31.266 T 14-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 LH59_03185 71c324c36216644aac540b566e8667c8 308 PIRSF PIRSF000401 1 308 8.2E-85 T 14-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 LH59_20880 1062db136e22efb1287b20e5d082b121 420 Pfam PF03600 Citrate transporter 41 341 2.2E-26 T 14-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 LH59_20880 1062db136e22efb1287b20e5d082b121 420 PRINTS PR00758 Arsenical pump membrane protein signature 276 300 6.3E-16 T 14-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 LH59_20880 1062db136e22efb1287b20e5d082b121 420 PRINTS PR00758 Arsenical pump membrane protein signature 107 131 6.3E-16 T 14-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 LH59_20880 1062db136e22efb1287b20e5d082b121 420 PRINTS PR00758 Arsenical pump membrane protein signature 358 383 6.3E-16 T 14-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 LH59_03680 a24c05ae547bb6efe95202c141dcd8b1 321 Pfam PF02653 Branched-chain amino acid transport system / permease component 33 295 3.1E-32 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_15390 95f7ee892ae05c6057634b3ea1107927 218 Pfam PF11445 Protein of unknown function (DUF2894) 2 194 1.7E-57 T 14-10-2018 IPR021549 Protein of unknown function DUF2894 LH59_17575 2484079e378999acf4c5d1ff6cf63a1a 670 SUPERFAMILY SSF53335 11 656 6.8E-57 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_17575 2484079e378999acf4c5d1ff6cf63a1a 670 Pfam PF00145 C-5 cytosine-specific DNA methylase 15 133 3.6E-8 T 14-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 LH59_17575 2484079e378999acf4c5d1ff6cf63a1a 670 Pfam PF00145 C-5 cytosine-specific DNA methylase 175 228 8.8E-5 T 14-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 LH59_15135 2ebe844049c6185d1a9867eec8088c6f 391 Pfam PF06772 Bacterial low temperature requirement A protein (LtrA) 19 377 9.2E-111 T 14-10-2018 IPR010640 Low temperature requirement A LH59_11470 770b1b8510bc98abffcf4b94c51ae072 262 TIGRFAM TIGR01400 fliR: flagellar biosynthetic protein FliR 15 254 1.9E-74 T 14-10-2018 IPR006303 Flagellar biosynthesis protein FliR GO:0016021|GO:0044780 LH59_11470 770b1b8510bc98abffcf4b94c51ae072 262 Pfam PF01311 Bacterial export proteins, family 1 15 246 7.9E-74 T 14-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 LH59_11470 770b1b8510bc98abffcf4b94c51ae072 262 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 203 222 1.4E-30 T 14-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 LH59_11470 770b1b8510bc98abffcf4b94c51ae072 262 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 181 203 1.4E-30 T 14-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 LH59_11470 770b1b8510bc98abffcf4b94c51ae072 262 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 81 100 1.4E-30 T 14-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 LH59_11470 770b1b8510bc98abffcf4b94c51ae072 262 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 22 43 1.4E-30 T 14-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 LH59_04900 4dc796879118eaa782811208835a8233 304 SUPERFAMILY SSF161098 87 292 9.16E-23 T 14-10-2018 IPR035906 MetI-like superfamily LH59_04900 4dc796879118eaa782811208835a8233 304 Gene3D G3DSA:1.10.3720.10 82 300 1.3E-20 T 14-10-2018 IPR035906 MetI-like superfamily LH59_04900 4dc796879118eaa782811208835a8233 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 110 303 5.0E-24 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_12030 090839dbc30ae7f85df3dec7bcffe754 381 Pfam PF12698 ABC-2 family transporter protein 33 372 7.4E-48 T 14-10-2018 LH59_07495 53cfff6640876cab92c9212ad87465cc 168 Gene3D G3DSA:3.30.300.130 6 102 2.4E-27 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily LH59_07495 53cfff6640876cab92c9212ad87465cc 168 TIGRFAM TIGR02159 PA_CoA_Oxy4: phenylacetate-CoA oxygenase, PaaJ subunit 19 167 2.9E-60 T 14-10-2018 IPR011883 Phenylacetate-CoA oxygenase, PaaJ subunit LH59_07495 53cfff6640876cab92c9212ad87465cc 168 SUPERFAMILY SSF117916 7 101 2.75E-27 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily LH59_07495 53cfff6640876cab92c9212ad87465cc 168 Pfam PF01883 Iron-sulfur cluster assembly protein 10 73 1.8E-13 T 14-10-2018 IPR002744 MIP18 family-like LH59_19270 fab6e8541c271400136eeec10045b447 209 Pfam PF01810 LysE type translocator 15 206 1.1E-25 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 LH59_14760 8f915ed3027be0198662cfb1572fdbf8 65 Pfam PF04328 Selenoprotein, putative 7 65 8.6E-30 T 14-10-2018 IPR007423 Selenoprotein, putative LH59_16655 a186cbf917fd0952cec0df8e44396dfa 182 SUPERFAMILY SSF52540 4 179 5.5E-17 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_16655 a186cbf917fd0952cec0df8e44396dfa 182 Gene3D G3DSA:3.40.50.300 1 181 1.0E-12 T 14-10-2018 LH59_01555 1b6d0ae6390c95d61abd11df08473701 245 Pfam PF01925 Sulfite exporter TauE/SafE 15 234 1.9E-16 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 LH59_02780 bcfbae89fa3372b82adfc9dc0a2faf79 276 Pfam PF01478 Type IV leader peptidase family 128 234 8.5E-23 T 14-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 LH59_02780 bcfbae89fa3372b82adfc9dc0a2faf79 276 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 13 116 2.1E-23 T 14-10-2018 IPR010627 Peptidase A24A, N-terminal LH59_02780 bcfbae89fa3372b82adfc9dc0a2faf79 276 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 135 152 1.9E-23 T 14-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial LH59_02780 bcfbae89fa3372b82adfc9dc0a2faf79 276 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 203 214 1.9E-23 T 14-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial LH59_02780 bcfbae89fa3372b82adfc9dc0a2faf79 276 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 192 202 1.9E-23 T 14-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial LH59_02780 bcfbae89fa3372b82adfc9dc0a2faf79 276 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 215 230 1.9E-23 T 14-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial LH59_02780 bcfbae89fa3372b82adfc9dc0a2faf79 276 Gene3D G3DSA:1.20.120.1220 117 235 1.7E-5 T 14-10-2018 LH59_23510 c8673e53972a8af42d791d934929cbe0 172 Pfam PF02308 MgtC family 32 156 2.3E-39 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 LH59_23510 c8673e53972a8af42d791d934929cbe0 172 PRINTS PR01837 MgtC/SapB protein signature 81 103 4.4E-42 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 LH59_23510 c8673e53972a8af42d791d934929cbe0 172 PRINTS PR01837 MgtC/SapB protein signature 35 54 4.4E-42 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 LH59_23510 c8673e53972a8af42d791d934929cbe0 172 PRINTS PR01837 MgtC/SapB protein signature 110 134 4.4E-42 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 LH59_23510 c8673e53972a8af42d791d934929cbe0 172 PRINTS PR01837 MgtC/SapB protein signature 54 72 4.4E-42 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 LH59_06700 d04baebd3d71a936e9771d429add5b81 114 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 77 2.2E-12 T 14-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain LH59_06700 d04baebd3d71a936e9771d429add5b81 114 SUPERFAMILY SSF54909 1 100 2.59E-26 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel LH59_06700 d04baebd3d71a936e9771d429add5b81 114 Gene3D G3DSA:3.30.70.100 1 93 2.1E-21 T 14-10-2018 LH59_05435 81f8f89446552c76e99f8d0b1b2f822c 29 TIGRFAM TIGR02115 potass_kdpF: K+-transporting ATPase, F subunit 6 29 5.2E-10 T 14-10-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 LH59_05435 81f8f89446552c76e99f8d0b1b2f822c 29 Pfam PF09604 F subunit of K+-transporting ATPase (Potass_KdpF) 6 29 7.0E-12 T 14-10-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 LH59_11690 763fd1a85242d5ff20316a4780e71d99 186 Gene3D G3DSA:3.30.910.20 43 184 3.1E-41 T 14-10-2018 IPR024930 Skp domain superfamily LH59_11690 763fd1a85242d5ff20316a4780e71d99 186 PIRSF PIRSF002094 23 186 6.2E-51 T 14-10-2018 IPR005632 Chaperone protein Skp GO:0051082 LH59_11690 763fd1a85242d5ff20316a4780e71d99 186 SUPERFAMILY SSF111384 43 184 4.97E-37 T 14-10-2018 LH59_11690 763fd1a85242d5ff20316a4780e71d99 186 SMART SM00935 33 185 1.7E-58 T 14-10-2018 IPR005632 Chaperone protein Skp GO:0051082 LH59_11690 763fd1a85242d5ff20316a4780e71d99 186 Pfam PF03938 Outer membrane protein (OmpH-like) 31 184 1.5E-36 T 14-10-2018 IPR005632 Chaperone protein Skp GO:0051082 LH59_15375 6b3bdcd2a5ef014d4dae06161ebc9cfd 300 Pfam PF11828 Protein of unknown function (DUF3348) 1 298 1.2E-93 T 14-10-2018 IPR021783 Protein of unknown function DUF3348 LH59_16520 80f7e9475cb5c5156baded30807cc7e3 251 Pfam PF07277 SapC 19 235 3.3E-71 T 14-10-2018 IPR010836 SapC LH59_19780 3ca1871c040818570bc597ed0df075c5 149 Pfam PF12266 Protein of unknown function (DUF3613) 79 141 9.5E-11 T 14-10-2018 IPR022053 Protein of unknown function DUF3613 LH59_20705 3b354d74693b7382e6fc078ea479aded 265 Pfam PF01925 Sulfite exporter TauE/SafE 6 259 3.4E-40 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 LH59_03605 0f54e43ea63cc3950585eeb4b61dddc7 240 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 4 176 1.4E-58 T 14-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LH59_03605 0f54e43ea63cc3950585eeb4b61dddc7 240 SUPERFAMILY SSF53098 1 174 3.66E-53 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily LH59_03605 0f54e43ea63cc3950585eeb4b61dddc7 240 Gene3D G3DSA:3.30.420.10 1 178 3.0E-53 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 LH59_03605 0f54e43ea63cc3950585eeb4b61dddc7 240 TIGRFAM TIGR01406 dnaQ_proteo: DNA polymerase III, epsilon subunit 2 232 2.0E-87 T 14-10-2018 IPR006309 DNA polymerase 3, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LH59_03605 0f54e43ea63cc3950585eeb4b61dddc7 240 SMART SM00479 2 174 6.7E-45 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III LH59_03605 0f54e43ea63cc3950585eeb4b61dddc7 240 Pfam PF00929 Exonuclease 4 164 2.3E-33 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III LH59_18685 217d30dcad07a3585e1ef2f8c62a2a3f 270 SMART SM00382 58 183 8.3E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain LH59_18685 217d30dcad07a3585e1ef2f8c62a2a3f 270 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 63 180 4.7E-10 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 LH59_18685 217d30dcad07a3585e1ef2f8c62a2a3f 270 Gene3D G3DSA:3.40.50.300 24 199 4.3E-16 T 14-10-2018 LH59_18685 217d30dcad07a3585e1ef2f8c62a2a3f 270 SUPERFAMILY SSF52540 59 237 2.26E-19 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_05155 0fe28cac50b74953a04523c4b17de781 267 Pfam PF07264 Etoposide-induced protein 2.4 (EI24) 27 240 1.7E-17 T 14-10-2018 LH59_22265 fc7a5b66d745fbc40681cc221f4dffaa 293 Pfam PF02653 Branched-chain amino acid transport system / permease component 12 282 1.9E-35 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_22330 286fcdce8e9b31ff9bb8a23d084eb6a6 190 SUPERFAMILY SSF158442 16 128 1.24E-22 T 14-10-2018 IPR023380 DsbB-like superfamily LH59_22330 286fcdce8e9b31ff9bb8a23d084eb6a6 190 Gene3D G3DSA:1.20.1550.10 3 102 1.3E-11 T 14-10-2018 IPR023380 DsbB-like superfamily LH59_22330 286fcdce8e9b31ff9bb8a23d084eb6a6 190 Pfam PF02600 Disulfide bond formation protein DsbB 12 96 7.5E-12 T 14-10-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 LH59_11305 f0d049b5b2f5fd976c367fdd70541bf9 289 TIGRFAM TIGR03818 MotA1: flagellar motor stator protein MotA 2 282 1.5E-118 T 14-10-2018 IPR022522 Flagellar motor stator, MotA LH59_11305 f0d049b5b2f5fd976c367fdd70541bf9 289 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 205 222 - T 14-10-2018 IPR000540 Flagellar motor protein MotA, conserved site LH59_11305 f0d049b5b2f5fd976c367fdd70541bf9 289 Pfam PF01618 MotA/TolQ/ExbB proton channel family 138 238 9.5E-11 T 14-10-2018 IPR002898 MotA/TolQ/ExbB proton channel LH59_23365 55cf1d15aad700a92f19d807ed5a5add 71 Pfam PF04102 SlyX 8 71 3.5E-19 T 14-10-2018 IPR007236 SlyX LH59_14745 9e5a7f599d8e8fe1133d57f94a3ea4be 379 PIRSF PIRSF004925 1 379 6.0E-86 T 14-10-2018 IPR026032 Probable 3-phenylpropionic acid transporter LH59_14745 9e5a7f599d8e8fe1133d57f94a3ea4be 379 Pfam PF12832 MFS_1 like family 2 349 3.5E-48 T 14-10-2018 IPR024989 Major facilitator superfamily associated domain LH59_14745 9e5a7f599d8e8fe1133d57f94a3ea4be 379 Gene3D G3DSA:1.20.1250.20 191 377 1.5E-34 T 14-10-2018 LH59_14745 9e5a7f599d8e8fe1133d57f94a3ea4be 379 SUPERFAMILY SSF103473 3 376 5.23E-45 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_14745 9e5a7f599d8e8fe1133d57f94a3ea4be 379 Gene3D G3DSA:1.20.1250.20 1 181 8.1E-22 T 14-10-2018 LH59_04150 f84362a0c0dd474e9ac92e1bbf7f2b11 363 TIGRFAM TIGR00698 TIGR00698: conserved hypothetical protein 35 359 4.0E-81 T 14-10-2018 IPR004630 Uncharacterised protein family UPF0324, bacteria GO:0016021 LH59_04150 f84362a0c0dd474e9ac92e1bbf7f2b11 363 Pfam PF03601 Conserved hypothetical protein 698 35 343 3.0E-91 T 14-10-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 LH59_14320 7d4117cc5a6309c7259b258a7b20c4f1 277 Pfam PF13827 Domain of unknown function (DUF4189) 165 255 6.8E-8 T 14-10-2018 IPR025240 Domain of unknown function DUF4189 LH59_14320 7d4117cc5a6309c7259b258a7b20c4f1 277 Pfam PF13827 Domain of unknown function (DUF4189) 34 125 1.0E-15 T 14-10-2018 IPR025240 Domain of unknown function DUF4189 LH59_20430 248ba381dabf68d8b960bfb902bdbb25 334 Gene3D G3DSA:1.20.1420.20 3 334 2.3E-73 T 14-10-2018 IPR038352 Imelysin-like domain superfamily LH59_20430 248ba381dabf68d8b960bfb902bdbb25 334 Pfam PF09375 Imelysin 15 310 4.9E-35 T 14-10-2018 IPR018976 Imelysin-like domain LH59_11150 7cd3354d34d15e9a458cb9b0469ddd8c 292 SUPERFAMILY SSF161098 85 278 1.7E-33 T 14-10-2018 IPR035906 MetI-like superfamily LH59_11150 7cd3354d34d15e9a458cb9b0469ddd8c 292 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 19 59 2.1E-12 T 14-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain LH59_11150 7cd3354d34d15e9a458cb9b0469ddd8c 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 290 3.8E-34 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_11150 7cd3354d34d15e9a458cb9b0469ddd8c 292 Gene3D G3DSA:1.10.3720.10 81 287 3.5E-28 T 14-10-2018 IPR035906 MetI-like superfamily LH59_28115 83522eda4e1cfd176cefa9d596cf5fc3 265 Pfam PF13614 AAA domain 11 185 9.0E-65 T 14-10-2018 IPR025669 AAA domain LH59_28115 83522eda4e1cfd176cefa9d596cf5fc3 265 Gene3D G3DSA:3.40.50.300 6 264 9.8E-78 T 14-10-2018 LH59_28115 83522eda4e1cfd176cefa9d596cf5fc3 265 SUPERFAMILY SSF52540 10 262 2.41E-64 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_28115 83522eda4e1cfd176cefa9d596cf5fc3 265 PIRSF PIRSF009320 95 263 1.2E-9 T 14-10-2018 LH59_28115 83522eda4e1cfd176cefa9d596cf5fc3 265 PIRSF PIRSF009320 10 92 7.4E-14 T 14-10-2018 LH59_08430 0a522659b0d0099005a724537c8899a4 325 PIRSF PIRSF018005 2 325 9.7E-106 T 14-10-2018 IPR017804 Methyltransferase EgtD-like GO:0008168 LH59_08430 0a522659b0d0099005a724537c8899a4 325 Gene3D G3DSA:3.40.50.150 53 225 1.2E-43 T 14-10-2018 LH59_08430 0a522659b0d0099005a724537c8899a4 325 TIGRFAM TIGR03438 egtD_ergothio: dimethylhistidine N-methyltransferase 27 321 3.6E-113 T 14-10-2018 IPR035094 Histidine N-alpha-methyltransferase KEGG: 00340+2.1.1.44|MetaCyc: PWY-7255|MetaCyc: PWY-7550 LH59_08430 0a522659b0d0099005a724537c8899a4 325 Pfam PF10017 Histidine-specific methyltransferase, SAM-dependent 28 324 1.8E-97 T 14-10-2018 IPR019257 Histidine-specific methyltransferase, SAM-dependent LH59_08430 0a522659b0d0099005a724537c8899a4 325 SUPERFAMILY SSF53335 43 323 6.57E-12 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_26870 f1862c44233878e2c53128d3db4ff122 354 Pfam PF02653 Branched-chain amino acid transport system / permease component 51 329 7.5E-30 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_18280 5cff5b6c442d5ab25a6aac080a1ac668 74 ProDom PD056452 UNCHARACTERIZED BACTERIA SIMILAR YPEB CYTOPLASMIC VCA0163 PRODUCT STM2426 GENE YPO2988 14 69 6.0E-22 T 14-10-2018 IPR024530 Putative quorum-sensing-regulated virulence factor LH59_18280 5cff5b6c442d5ab25a6aac080a1ac668 74 Pfam PF12843 Putative quorum-sensing-regulated virulence factor 2 67 3.5E-31 T 14-10-2018 IPR024530 Putative quorum-sensing-regulated virulence factor LH59_10820 6d455521263fffbe3b2dedb4ec0f9681 337 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 51 3.9E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_10820 6d455521263fffbe3b2dedb4ec0f9681 337 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 51 62 3.9E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_10820 6d455521263fffbe3b2dedb4ec0f9681 337 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 41 3.9E-6 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_10820 6d455521263fffbe3b2dedb4ec0f9681 337 Pfam PF03466 LysR substrate binding domain 101 295 5.5E-18 T 14-10-2018 IPR005119 LysR, substrate-binding LH59_10820 6d455521263fffbe3b2dedb4ec0f9681 337 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 19 73 1.5E-17 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 LH59_10820 6d455521263fffbe3b2dedb4ec0f9681 337 SUPERFAMILY SSF46785 7 122 4.13E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily LH59_10820 6d455521263fffbe3b2dedb4ec0f9681 337 Gene3D G3DSA:3.40.190.10 175 270 1.5E-17 T 14-10-2018 LH59_10820 6d455521263fffbe3b2dedb4ec0f9681 337 Gene3D G3DSA:1.10.10.10 14 99 2.0E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily LH59_10820 6d455521263fffbe3b2dedb4ec0f9681 337 Gene3D G3DSA:3.40.190.10 105 174 1.5E-17 T 14-10-2018 LH59_10820 6d455521263fffbe3b2dedb4ec0f9681 337 SUPERFAMILY SSF53850 103 271 1.47E-18 T 14-10-2018 LH59_18355 7e5d8170f684820b4f8c280d0c85fe3f 141 Gene3D G3DSA:2.40.128.640 33 141 2.6E-36 T 14-10-2018 LH59_18355 7e5d8170f684820b4f8c280d0c85fe3f 141 Pfam PF04170 NlpE N-terminal domain 46 129 2.7E-26 T 14-10-2018 IPR007298 Copper resistance lipoprotein NlpE LH59_24695 95d819b155c629a7974bcae0df132a80 371 Pfam PF13579 Glycosyl transferase 4-like domain 13 172 2.4E-12 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 LH59_24695 95d819b155c629a7974bcae0df132a80 371 SUPERFAMILY SSF53756 2 366 3.14E-72 T 14-10-2018 LH59_24695 95d819b155c629a7974bcae0df132a80 371 Gene3D G3DSA:3.40.50.2000 13 361 1.3E-58 T 14-10-2018 LH59_24695 95d819b155c629a7974bcae0df132a80 371 Pfam PF00534 Glycosyl transferases group 1 185 343 3.1E-33 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 LH59_24695 95d819b155c629a7974bcae0df132a80 371 Gene3D G3DSA:3.40.50.2000 173 351 1.3E-58 T 14-10-2018 LH59_11820 66505fbe3a9b981e7b0e5fc47b40519e 349 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 20 225 1.7E-64 T 14-10-2018 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 LH59_11820 66505fbe3a9b981e7b0e5fc47b40519e 349 SUPERFAMILY SSF52540 8 230 1.04E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase LH59_11820 66505fbe3a9b981e7b0e5fc47b40519e 349 Gene3D G3DSA:3.40.50.300 6 193 1.2E-49 T 14-10-2018 LH59_11820 66505fbe3a9b981e7b0e5fc47b40519e 349 Pfam PF13177 DNA polymerase III, delta subunit 21 192 7.5E-38 T 14-10-2018 LH59_00355 31bde7f9d4f3357b6915b3afed5c5eb1 674 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 139 588 3.1E-114 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit LH59_00355 31bde7f9d4f3357b6915b3afed5c5eb1 674 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 29 664 5.6E-211 T 14-10-2018 IPR011853 TRAP C4-dicarboxylate transport system permease, fused DctM-DctQ LH59_00610 b0d9b2d0c875f15b7646ff13ff7bca44 232 SUPERFAMILY SSF55469 17 230 1.14E-43 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 LH59_00610 b0d9b2d0c875f15b7646ff13ff7bca44 232 Pfam PF00881 Nitroreductase family 20 207 9.5E-30 T 14-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 LH59_00610 b0d9b2d0c875f15b7646ff13ff7bca44 232 Gene3D G3DSA:3.40.109.10 1 227 8.0E-63 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 LH59_04360 d05ca59e8084ee9a70bd70aaa5fc70ca 228 SUPERFAMILY SSF53448 1 223 1.96E-55 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases LH59_04360 d05ca59e8084ee9a70bd70aaa5fc70ca 228 Gene3D G3DSA:3.90.550.10 1 225 1.1E-55 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases LH59_04360 d05ca59e8084ee9a70bd70aaa5fc70ca 228 Pfam PF00483 Nucleotidyl transferase 3 221 6.8E-23 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 LH59_13050 217b97875769dcc3c7a055aa1781fbfb 388 SUPERFAMILY SSF56300 160 385 2.85E-40 T 14-10-2018 LH59_13050 217b97875769dcc3c7a055aa1781fbfb 388 Pfam PF00149 Calcineurin-like phosphoesterase 160 328 3.4E-10 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 LH59_13050 217b97875769dcc3c7a055aa1781fbfb 388 Gene3D G3DSA:3.60.21.10 159 345 4.7E-21 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like LH59_09370 52e52375656b4472d02dcc5253627075 279 Gene3D G3DSA:3.30.2010.10 73 165 2.5E-5 T 14-10-2018 LH59_09370 52e52375656b4472d02dcc5253627075 279 Pfam PF01435 Peptidase family M48 78 261 3.9E-37 T 14-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 LH59_26625 6d274117ce417e7d7386b4cb3f3a9330 210 Pfam PF06835 Lipopolysaccharide-assembly, LptC-related 12 180 5.2E-39 T 14-10-2018 IPR010664 Lipopolysaccharide assembly, LptC-related LH59_26625 6d274117ce417e7d7386b4cb3f3a9330 210 TIGRFAM TIGR04409 LptC_YrbK: LPS export ABC transporter periplasmic protein LptC 8 181 1.2E-39 T 14-10-2018 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 LH59_26945 90e51c3fed47cda3ddd5fc71fcd08bfc 282 Gene3D G3DSA:1.20.1270.180 23 120 5.4E-7 T 14-10-2018 LH59_26945 90e51c3fed47cda3ddd5fc71fcd08bfc 282 Pfam PF07007 Lysozyme inhibitor LprI 30 92 4.0E-8 T 14-10-2018 IPR009739 Lysozyme inhibitor LprI, N-terminal LH59_14170 a40cfb1d385931a4c885a649fad5ac3d 437 SUPERFAMILY SSF103473 19 434 1.44E-59 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_14170 a40cfb1d385931a4c885a649fad5ac3d 437 Gene3D G3DSA:1.20.1250.20 21 436 9.0E-61 T 14-10-2018 LH59_14170 a40cfb1d385931a4c885a649fad5ac3d 437 ProSitePatterns PS00217 Sugar transport proteins signature 2. 136 161 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 LH59_14170 a40cfb1d385931a4c885a649fad5ac3d 437 Pfam PF07690 Major Facilitator Superfamily 68 393 1.3E-24 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_08795 09d5b2ef6c3babe6d40d3cd0dc874b8b 233 Pfam PF11254 Protein of unknown function (DUF3053) 11 227 8.0E-73 T 14-10-2018 IPR021413 Protein of unknown function DUF3053 LH59_26705 92cb2968df43cf7f56bc443ae6dfe9c1 164 SUPERFAMILY SSF52833 21 162 6.75E-40 T 14-10-2018 IPR036249 Thioredoxin-like superfamily LH59_26705 92cb2968df43cf7f56bc443ae6dfe9c1 164 Gene3D G3DSA:3.40.30.10 20 163 6.8E-42 T 14-10-2018 LH59_26705 92cb2968df43cf7f56bc443ae6dfe9c1 164 Pfam PF08534 Redoxin 26 149 4.5E-26 T 14-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 LH59_08220 02052c8502d37a29bfaf3b4cb4f545ab 272 Pfam PF01925 Sulfite exporter TauE/SafE 9 262 1.8E-55 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 LH59_23425 5e9099efedb1e9eb0d19f64ea3334039 256 Pfam PF01925 Sulfite exporter TauE/SafE 19 248 1.5E-29 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 LH59_16120 7b2a274affd9ec646d7abfaf73be5334 129 Pfam PF04134 Protein of unknown function, DUF393 11 116 1.5E-9 T 14-10-2018 IPR007263 Protein of unknown function DUF393 LH59_18410 3b0d1e6ef2a33cb3f396c2b149cc0a6f 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 305 5.0E-43 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_18410 3b0d1e6ef2a33cb3f396c2b149cc0a6f 307 Gene3D G3DSA:1.10.3720.10 86 298 2.5E-26 T 14-10-2018 IPR035906 MetI-like superfamily LH59_18410 3b0d1e6ef2a33cb3f396c2b149cc0a6f 307 SUPERFAMILY SSF161098 92 291 3.27E-19 T 14-10-2018 IPR035906 MetI-like superfamily LH59_01185 d98c6b601f02f3e180e5fbeba6e9350a 272 Pfam PF05433 Glycine zipper 2TM domain 181 221 4.3E-8 T 14-10-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 LH59_25540 33a075b4e4710701cab6c21218692302 107 Pfam PF12779 YXWGXW repeat (2 copies) 52 77 4.9E-8 T 14-10-2018 IPR024447 YXWGXW repeat LH59_23030 adbb06d12973da62337fed97c6c096c6 466 Pfam PF07394 Protein of unknown function (DUF1501) 44 401 1.7E-47 T 14-10-2018 IPR010869 Protein of unknown function DUF1501 LH59_12510 49cfbefa46073e41b504949551818bce 227 Pfam PF11010 Protein of unknown function (DUF2848) 25 218 7.4E-79 T 14-10-2018 IPR021269 Protein of unknown function DUF2848 LH59_09300 ec8f60f583241a30aaaa3875b4102b56 281 Pfam PF00482 Type II secretion system (T2SS), protein F 114 237 2.7E-17 T 14-10-2018 IPR018076 Type II secretion system F domain LH59_09300 ec8f60f583241a30aaaa3875b4102b56 281 Gene3D G3DSA:1.20.81.30 100 216 3.7E-10 T 14-10-2018 LH59_02965 b43bb2b8d2208ec95b3963319b6b12f0 134 SUPERFAMILY SSF55298 2 133 1.37E-32 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 LH59_02965 b43bb2b8d2208ec95b3963319b6b12f0 134 Gene3D G3DSA:3.30.1330.40 8 133 1.4E-31 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 LH59_02965 b43bb2b8d2208ec95b3963319b6b12f0 134 Pfam PF01042 Endoribonuclease L-PSP 26 132 1.1E-21 T 14-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 LH59_19775 c6a26771ec81b21fc8834d0d99a7ccae 699 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 16 60 2.8E-5 T 14-10-2018 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal LH59_16785 241509c663730e11225e1e4749817a64 109 Pfam PF02656 Domain of unknown function (DUF202) 6 65 1.1E-9 T 14-10-2018 IPR003807 Domain of unknown function DUF202 LH59_16785 241509c663730e11225e1e4749817a64 109 ProDom PD277113 MEMBRANE INNER YIDG TRANSMEMBRANE STY3975 RV2273/MT2334 MB2296 5 63 6.0E-5 T 14-10-2018 IPR020264 Uncharacterised protein family YidG LH59_28150 ea58dde89012352d1eb1697487967bc2 145 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 6 137 3.8E-21 T 14-10-2018 IPR009936 Protein of unknown function DUF1468 LH59_22400 ad2523a466f03cc2a3520809937c695a 156 TIGRFAM TIGR03293 PhnG_redo: phosphonate C-P lyase system protein PhnG 13 155 8.2E-52 T 14-10-2018 IPR009609 Phosphonate metabolism PhnG GO:0015716|GO:0019634 KEGG: 00440+2.7.8.37|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 LH59_22400 ad2523a466f03cc2a3520809937c695a 156 Pfam PF06754 Phosphonate metabolism protein PhnG 14 154 1.5E-51 T 14-10-2018 IPR009609 Phosphonate metabolism PhnG GO:0015716|GO:0019634 KEGG: 00440+2.7.8.37|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 LH59_19870 803288711ad7b530e6ddd916009f9519 325 Gene3D G3DSA:1.10.3720.10 106 317 2.4E-13 T 14-10-2018 IPR035906 MetI-like superfamily LH59_19870 803288711ad7b530e6ddd916009f9519 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 130 323 8.5E-28 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_19870 803288711ad7b530e6ddd916009f9519 325 SUPERFAMILY SSF161098 109 306 8.01E-12 T 14-10-2018 IPR035906 MetI-like superfamily LH59_26930 9e7151612972df54a0e5e11b296b5bbf 154 SUPERFAMILY SSF54197 5 131 9.19E-35 T 14-10-2018 IPR036265 HIT-like superfamily LH59_26930 9e7151612972df54a0e5e11b296b5bbf 154 Pfam PF01230 HIT domain 25 100 4.9E-12 T 14-10-2018 IPR001310 Histidine triad (HIT) protein LH59_26930 9e7151612972df54a0e5e11b296b5bbf 154 Gene3D G3DSA:3.30.428.10 13 150 1.4E-34 T 14-10-2018 IPR036265 HIT-like superfamily LH59_17945 1e19d35c648ce1b2b73733e3129f8e13 137 Gene3D G3DSA:3.30.420.270 60 131 1.1E-6 T 14-10-2018 LH59_17945 1e19d35c648ce1b2b73733e3129f8e13 137 Pfam PF02472 Biopolymer transport protein ExbD/TolR 10 134 2.4E-25 T 14-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 LH59_19345 5d51ed473c1b08915f446b456d612141 163 Gene3D G3DSA:3.30.240.20 94 163 1.8E-19 T 14-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily LH59_19345 5d51ed473c1b08915f446b456d612141 163 Pfam PF04239 Protein of unknown function (DUF421) 100 162 1.2E-13 T 14-10-2018 IPR007353 Protein of unknown function DUF421 LH59_09000 c2c895647486d6129171b56407236001 203 Pfam PF14317 YcxB-like protein 129 187 1.4E-9 T 14-10-2018 IPR025588 YcxB-like protein LH59_13315 fa70631774da375c66223f87658596c0 157 Pfam PF04657 Putative inner membrane exporter, YdcZ 10 146 8.2E-37 T 14-10-2018 IPR006750 Putative inner membrane exporter, YdcZ LH59_17870 31f418c3c50c6d5842adae7a2457fd50 554 Pfam PF02470 MlaD protein 172 232 6.5E-8 T 14-10-2018 IPR003399 Mce/MlaD LH59_17870 31f418c3c50c6d5842adae7a2457fd50 554 Pfam PF02470 MlaD protein 54 141 1.6E-10 T 14-10-2018 IPR003399 Mce/MlaD LH59_17870 31f418c3c50c6d5842adae7a2457fd50 554 Pfam PF02470 MlaD protein 303 408 4.8E-12 T 14-10-2018 IPR003399 Mce/MlaD LH59_00170 ff97c67e48c5efb4f42afe482531de51 576 Pfam PF02538 Hydantoinase B/oxoprolinase 17 540 2.5E-169 T 14-10-2018 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 LH59_02845 48a9f58acfeb3ca0b0ff2ce7c4c5fb02 314 Gene3D G3DSA:1.10.3720.10 65 307 5.5E-59 T 14-10-2018 IPR035906 MetI-like superfamily LH59_02845 48a9f58acfeb3ca0b0ff2ce7c4c5fb02 314 SUPERFAMILY SSF161098 72 294 1.24E-51 T 14-10-2018 IPR035906 MetI-like superfamily LH59_02845 48a9f58acfeb3ca0b0ff2ce7c4c5fb02 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 306 1.5E-15 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 LH59_13575 3743425f2b1bdb1da62788619f57a506 368 Pfam PF01594 AI-2E family transporter 18 347 7.9E-32 T 14-10-2018 IPR002549 Transmembrane protein TqsA-like LH59_15665 299fde98c2a66902372a05b563036975 353 SUPERFAMILY SSF53686 11 351 1.65E-73 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme LH59_15665 299fde98c2a66902372a05b563036975 353 Gene3D G3DSA:3.40.50.1100 58 166 4.9E-97 T 14-10-2018 LH59_15665 299fde98c2a66902372a05b563036975 353 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 18 340 1.6E-45 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme LH59_15665 299fde98c2a66902372a05b563036975 353 PIRSF PIRSF006278 1 353 5.9E-93 T 14-10-2018 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase LH59_15665 299fde98c2a66902372a05b563036975 353 Gene3D G3DSA:3.40.50.1100 20 346 4.9E-97 T 14-10-2018 LH59_17845 da450aa212df805e4e3060a13df6f47e 362 Pfam PF02653 Branched-chain amino acid transport system / permease component 41 318 9.1E-53 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_23320 e1f8a29f61f5c4aeba19d57109c850f9 125 Pfam PF13663 Domain of unknown function (DUF4148) 1 76 2.3E-7 T 14-10-2018 IPR025421 Protein of unknown function DUF4148 LH59_08460 37a0676e9cd8f55082a81acf10e969da 302 SUPERFAMILY SSF103481 193 291 1.31E-12 T 14-10-2018 LH59_08460 37a0676e9cd8f55082a81acf10e969da 302 Pfam PF00892 EamA-like transporter family 155 289 3.8E-15 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_08460 37a0676e9cd8f55082a81acf10e969da 302 Pfam PF00892 EamA-like transporter family 18 143 1.8E-14 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 LH59_08460 37a0676e9cd8f55082a81acf10e969da 302 SUPERFAMILY SSF103481 44 145 2.22E-12 T 14-10-2018 LH59_01090 9e9fbf7837a033682b6f018278958ae3 267 Gene3D G3DSA:3.30.70.1290 29 167 1.3E-11 T 14-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 LH59_01090 9e9fbf7837a033682b6f018278958ae3 267 SUPERFAMILY SSF143422 35 107 9.22E-5 T 14-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 LH59_04265 2f0843cdc1570a2dc7dc1110b4cb77bd 157 Pfam PF03692 Putative zinc- or iron-chelating domain 27 120 2.2E-9 T 14-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein LH59_02425 49f0132d69e0a9fcf8651df7312ddbca 143 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 11 131 5.2E-7 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain LH59_02425 49f0132d69e0a9fcf8651df7312ddbca 143 Gene3D G3DSA:3.10.180.10 3 140 1.6E-37 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_02425 49f0132d69e0a9fcf8651df7312ddbca 143 SUPERFAMILY SSF54593 10 139 8.19E-24 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase LH59_22850 12ce2e6030e8885a9423917acdf524b6 464 Gene3D G3DSA:1.20.1250.20 4 371 1.5E-33 T 14-10-2018 LH59_22850 12ce2e6030e8885a9423917acdf524b6 464 SUPERFAMILY SSF103473 9 368 4.84E-42 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_22850 12ce2e6030e8885a9423917acdf524b6 464 Pfam PF07690 Major Facilitator Superfamily 207 374 3.8E-14 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_22850 12ce2e6030e8885a9423917acdf524b6 464 Pfam PF07690 Major Facilitator Superfamily 12 184 7.9E-10 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_27055 2d01c0c9917c2c28111951f79ad0e233 111 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 1 103 6.3E-33 T 14-10-2018 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV LH59_26865 46c181c253330ec0db32b04605d64c13 309 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 295 8.3E-30 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_09890 0fcbf1cf3c657c70e0b2227fe8feb7bb 239 Gene3D G3DSA:3.60.21.10 4 222 1.7E-46 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like LH59_09890 0fcbf1cf3c657c70e0b2227fe8feb7bb 239 SUPERFAMILY SSF56300 14 220 4.1E-37 T 14-10-2018 LH59_09890 0fcbf1cf3c657c70e0b2227fe8feb7bb 239 Pfam PF00149 Calcineurin-like phosphoesterase 18 190 1.3E-10 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 LH59_13455 9b66dc589ca4138dbef0f8d38cd6e934 90 SUPERFAMILY SSF160272 7 72 4.58E-5 T 14-10-2018 IPR036692 Shew3726-like superfamily LH59_13455 9b66dc589ca4138dbef0f8d38cd6e934 90 Pfam PF07369 Protein of unknown function (DUF1488) 8 72 3.2E-8 T 14-10-2018 IPR009962 Protein of unknown function DUF1488 LH59_27605 0608f5fbc382d18832379a6eb4ebdc07 101 Pfam PF13663 Domain of unknown function (DUF4148) 61 97 5.5E-10 T 14-10-2018 IPR025421 Protein of unknown function DUF4148 LH59_27605 0608f5fbc382d18832379a6eb4ebdc07 101 Pfam PF13663 Domain of unknown function (DUF4148) 1 58 8.8E-13 T 14-10-2018 IPR025421 Protein of unknown function DUF4148 LH59_07875 dca42394444df88104d5315ac98281a8 189 Pfam PF09335 SNARE associated Golgi protein 25 146 3.9E-19 T 14-10-2018 IPR032816 SNARE associated Golgi protein LH59_12250 8fb7e47802e52c032db0cd09e1879700 543 Pfam PF00361 Proton-conducting membrane transporter 137 437 1.1E-34 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 LH59_26160 603179c1d65f4da136b271a6b7a813e9 207 PIRSF PIRSF006324 1 202 2.6E-46 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 LH59_26160 603179c1d65f4da136b271a6b7a813e9 207 Pfam PF01810 LysE type translocator 9 200 6.5E-30 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 LH59_08300 9b1cf30a14064bef90b3302e432948db 146 Pfam PF11681 Protein of unknown function (DUF3277) 1 144 1.1E-63 T 14-10-2018 IPR021695 Bacteriophage rv5, Orf52 LH59_20215 dc721fa4032b01d286a1962da3c5cf7d 205 Gene3D G3DSA:3.90.79.10 43 202 2.3E-34 T 14-10-2018 LH59_20215 dc721fa4032b01d286a1962da3c5cf7d 205 Pfam PF12535 Hydrolase of X-linked nucleoside diphosphate N terminal 5 57 5.6E-14 T 14-10-2018 LH59_20215 dc721fa4032b01d286a1962da3c5cf7d 205 SUPERFAMILY SSF55811 51 194 4.2E-28 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 LH59_20215 dc721fa4032b01d286a1962da3c5cf7d 205 Pfam PF00293 NUDIX domain 73 176 6.2E-14 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 LH59_25495 985537e59bbf6b578aefba3c3ea0139e 462 Pfam PF12679 ABC-2 family transporter protein 4 293 1.8E-24 T 14-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 LH59_19355 2c8805f866d8853e1e48fb00063eb09e 156 Pfam PF04120 Low affinity iron permease 32 153 6.4E-48 T 14-10-2018 IPR007251 Low affinity iron permease, Fet4 GO:0055085 LH59_06630 a3945baf861b1b7af0ece57166e2607f 405 SUPERFAMILY SSF53822 29 403 1.98E-85 T 14-10-2018 IPR028082 Periplasmic binding protein-like I LH59_06630 a3945baf861b1b7af0ece57166e2607f 405 Gene3D G3DSA:3.40.50.2300 33 342 7.4E-103 T 14-10-2018 LH59_06630 a3945baf861b1b7af0ece57166e2607f 405 Pfam PF13458 Periplasmic binding protein 29 368 6.5E-90 T 14-10-2018 IPR028081 Leucine-binding protein domain LH59_06630 a3945baf861b1b7af0ece57166e2607f 405 Gene3D G3DSA:3.40.50.2300 150 281 7.4E-103 T 14-10-2018 LH59_05360 b0e334c9de2433577c211d6488fd6558 117 Gene3D G3DSA:1.10.760.10 35 117 1.8E-21 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_05360 b0e334c9de2433577c211d6488fd6558 117 SUPERFAMILY SSF46626 13 117 4.51E-19 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 LH59_05360 b0e334c9de2433577c211d6488fd6558 117 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 45 112 3.9E-6 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 LH59_03345 720494b0ba9ea29e79338cd654d666c6 293 Pfam PF02653 Branched-chain amino acid transport system / permease component 6 277 4.6E-49 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_15805 ddd5ebe730e7e94f89e1f4dfc448529a 490 Gene3D G3DSA:3.90.1300.10 11 485 4.3E-135 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_15805 ddd5ebe730e7e94f89e1f4dfc448529a 490 Pfam PF01425 Amidase 36 467 4.4E-91 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_15805 ddd5ebe730e7e94f89e1f4dfc448529a 490 SUPERFAMILY SSF75304 12 476 1.7E-125 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 LH59_15805 ddd5ebe730e7e94f89e1f4dfc448529a 490 ProSitePatterns PS00571 Amidases signature. 165 196 - T 14-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 LH59_23350 2eeef56af5895d4f0b36e0ea61c86b70 116 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 25 98 5.7E-14 T 14-10-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 LH59_23350 2eeef56af5895d4f0b36e0ea61c86b70 116 TIGRFAM TIGR02847 CyoD: cytochrome o ubiquinol oxidase subunit IV 18 112 2.4E-34 T 14-10-2018 IPR014210 Cytochrome o ubiquinol oxidase subunit IV GO:0008827|GO:0015990|GO:0016021 LH59_05565 533507f9d4798774cc698664048ec19f 302 SMART SM01130 8 301 7.5E-72 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_05565 533507f9d4798774cc698664048ec19f 302 Gene3D G3DSA:3.20.20.70 7 300 1.9E-83 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_05565 533507f9d4798774cc698664048ec19f 302 SUPERFAMILY SSF51569 9 297 4.5E-66 T 14-10-2018 LH59_05565 533507f9d4798774cc698664048ec19f 302 PIRSF PIRSF001365 6 299 2.0E-50 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_05565 533507f9d4798774cc698664048ec19f 302 PRINTS PR00146 Dihydrodipicolinate synthase signature 138 155 6.3E-7 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_05565 533507f9d4798774cc698664048ec19f 302 PRINTS PR00146 Dihydrodipicolinate synthase signature 41 62 6.3E-7 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_05565 533507f9d4798774cc698664048ec19f 302 PRINTS PR00146 Dihydrodipicolinate synthase signature 77 95 6.3E-7 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_05565 533507f9d4798774cc698664048ec19f 302 Pfam PF00701 Dihydrodipicolinate synthetase family 10 297 5.6E-36 T 14-10-2018 IPR002220 DapA-like GO:0016829 LH59_11175 2ec21f2734c6df09d0ace4800f609573 474 Gene3D G3DSA:1.20.1250.20 272 468 1.4E-16 T 14-10-2018 LH59_11175 2ec21f2734c6df09d0ace4800f609573 474 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 29 432 5.8E-70 T 14-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 LH59_11175 2ec21f2734c6df09d0ace4800f609573 474 Gene3D G3DSA:1.20.1720.10 26 236 9.4E-41 T 14-10-2018 LH59_11175 2ec21f2734c6df09d0ace4800f609573 474 Pfam PF07690 Major Facilitator Superfamily 31 424 9.9E-48 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_11175 2ec21f2734c6df09d0ace4800f609573 474 SUPERFAMILY SSF103473 19 470 1.44E-60 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_09770 f97523967ae16a9ad75664645c867bc9 197 Pfam PF04366 Las17-binding protein actin regulator 110 193 3.5E-14 T 14-10-2018 IPR007461 Ysc84 actin-binding domain LH59_27005 1f22e45a7da682bd6c4ab9cdb908ca42 393 Pfam PF02636 Putative S-adenosyl-L-methionine-dependent methyltransferase 89 321 1.0E-54 T 14-10-2018 IPR003788 Protein arginine methyltransferase NDUFAF7 Reactome: R-HSA-6799198 LH59_27005 1f22e45a7da682bd6c4ab9cdb908ca42 393 Gene3D G3DSA:3.40.50.12710 8 393 9.6E-132 T 14-10-2018 IPR038375 Protein arginine methyltransferase NDUFAF7 superfamily Reactome: R-HSA-6799198 LH59_27005 1f22e45a7da682bd6c4ab9cdb908ca42 393 SUPERFAMILY SSF53335 25 385 4.14E-92 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase LH59_23680 e5beca80f6d84dca281e608ef4934473 191 Pfam PF02698 DUF218 domain 39 179 1.6E-21 T 14-10-2018 IPR003848 Domain of unknown function DUF218 LH59_23305 1e5eca219b8825a286fde73dbd32f33e 144 Pfam PF11162 Protein of unknown function (DUF2946) 21 141 1.1E-9 T 14-10-2018 IPR021333 Protein of unknown function DUF2946 LH59_21290 0fcb4c576973867f25b54997bf37216a 545 Gene3D G3DSA:3.50.50.60 56 383 5.3E-23 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_21290 0fcb4c576973867f25b54997bf37216a 545 SUPERFAMILY SSF51905 58 540 2.55E-22 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily LH59_21290 0fcb4c576973867f25b54997bf37216a 545 Pfam PF13450 NAD(P)-binding Rossmann-like domain 63 130 2.2E-10 T 14-10-2018 LH59_11060 1c9079fe8a510cc1df62ba81d0b28e77 251 Pfam PF01203 Type II secretion system (T2SS), protein N 42 243 1.4E-22 T 14-10-2018 IPR022792 Type II secretion system, protein N LH59_25655 7e92f37c5539769fdc4bbaa9da8cd843 79 Pfam PF12167 Arm DNA-binding domain 6 67 1.7E-16 T 14-10-2018 IPR022000 Min27-like integrase, DNA-binding domain LH59_06710 6ceaf5f05221732f9f47d26561fcb9e1 277 Pfam PF13460 NAD(P)H-binding 9 196 5.1E-13 T 14-10-2018 IPR016040 NAD(P)-binding domain LH59_06710 6ceaf5f05221732f9f47d26561fcb9e1 277 SUPERFAMILY SSF51735 9 253 9.21E-40 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily LH59_06710 6ceaf5f05221732f9f47d26561fcb9e1 277 Gene3D G3DSA:3.40.50.720 1 277 1.4E-81 T 14-10-2018 LH59_22145 ea7ddca58838d67b6d6fd1e1596c6adc 254 Gene3D G3DSA:3.90.226.10 5 250 4.2E-77 T 14-10-2018 LH59_22145 ea7ddca58838d67b6d6fd1e1596c6adc 254 SUPERFAMILY SSF52096 3 247 1.11E-74 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily LH59_22145 ea7ddca58838d67b6d6fd1e1596c6adc 254 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 245 7.8E-52 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 LH59_27850 288fb483a96849377b47a71a667a46a2 327 Pfam PF02653 Branched-chain amino acid transport system / permease component 36 313 1.9E-35 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_15510 69c39f487659838ce6041a2c3145791c 259 Pfam PF11745 Protein of unknown function (DUF3304) 15 136 4.8E-14 T 14-10-2018 IPR021733 Protein of unknown function DUF3304 LH59_18570 a7c9f03922adfddbe462b7dc8e4c3d97 141 Pfam PF03653 Uncharacterised protein family (UPF0093) 2 141 1.2E-17 T 14-10-2018 IPR005265 Uncharacterised protein family UPF0093 LH59_18570 a7c9f03922adfddbe462b7dc8e4c3d97 141 PIRSF PIRSF004638 1 141 1.5E-23 T 14-10-2018 IPR005265 Uncharacterised protein family UPF0093 LH59_04595 514d746e044142dbe109ed5416d7f868 206 Pfam PF09335 SNARE associated Golgi protein 40 164 2.1E-21 T 14-10-2018 IPR032816 SNARE associated Golgi protein LH59_12565 491e6b8aa106e03106277eb73075adac 166 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 24 154 1.2E-23 T 14-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ LH59_06620 05288e4d1517edbc5283b1b17c280fa0 344 Pfam PF03739 Predicted permease YjgP/YjgQ family 2 334 1.6E-49 T 14-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 LH59_06620 05288e4d1517edbc5283b1b17c280fa0 344 TIGRFAM TIGR04407 LptF_YjgP: LPS export ABC transporter permease LptF 1 333 4.9E-95 T 14-10-2018 IPR030922 LPS export ABC transporter permease LptF GO:0043190|GO:0055085 LH59_14060 f6aef6404a8df8a9f87c38579e68d99f 213 Pfam PF09335 SNARE associated Golgi protein 47 170 2.3E-21 T 14-10-2018 IPR032816 SNARE associated Golgi protein LH59_24635 6628ed1986abfc8398966649840f846c 164 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 27 155 9.8E-27 T 14-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ LH59_20685 76a4463bffdefea9dec8a40e69a53e8b 407 SUPERFAMILY SSF52402 3 241 5.87E-40 T 14-10-2018 LH59_20685 76a4463bffdefea9dec8a40e69a53e8b 407 Gene3D G3DSA:3.40.50.620 4 262 2.8E-32 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold LH59_20685 76a4463bffdefea9dec8a40e69a53e8b 407 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 29 82 3.4E-7 T 14-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 LH59_20685 76a4463bffdefea9dec8a40e69a53e8b 407 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 151 241 9.7E-8 T 14-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 LH59_20685 76a4463bffdefea9dec8a40e69a53e8b 407 Pfam PF11922 Domain of unknown function (DUF3440) 245 351 3.4E-29 T 14-10-2018 IPR021845 Protein of unknown function DUF3440 LH59_27380 2913bc0355ed3fc77981e5bd366626f4 313 Pfam PF13480 Acetyltransferase (GNAT) domain 125 250 4.0E-8 T 14-10-2018 IPR038740 BioF2-like, acetyltransferase domain KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 LH59_27380 2913bc0355ed3fc77981e5bd366626f4 313 Gene3D G3DSA:3.40.630.30 122 268 3.4E-13 T 14-10-2018 LH59_27380 2913bc0355ed3fc77981e5bd366626f4 313 SUPERFAMILY SSF55729 122 275 9.02E-23 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_17850 f680403765470ac6c0042c1c17245b80 309 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 293 6.6E-45 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_06335 2d478627ca3cc45a994d7d7f2bc133ff 327 Pfam PF02653 Branched-chain amino acid transport system / permease component 27 302 2.2E-34 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_26330 d3700ebc1a926e2f175dda92813c8f1a 190 Gene3D G3DSA:3.30.1360.200 36 171 1.1E-15 T 14-10-2018 LH59_09270 402283f12c5fdf7e2ca16cd332271d1a 446 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 8 53 1.3E-5 T 14-10-2018 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal LH59_05775 8966c3f488a44da55e4bbba46f7efbcf 199 Pfam PF00881 Nitroreductase family 10 177 4.8E-15 T 14-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 LH59_05775 8966c3f488a44da55e4bbba46f7efbcf 199 SUPERFAMILY SSF55469 5 198 1.18E-67 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 LH59_05775 8966c3f488a44da55e4bbba46f7efbcf 199 Gene3D G3DSA:3.40.109.10 2 199 9.6E-82 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 LH59_03455 ec5e11fce38273380ea0fbccdfb4199e 419 SUPERFAMILY SSF53300 248 356 1.67E-6 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily LH59_03455 ec5e11fce38273380ea0fbccdfb4199e 419 Hamap MF_01232 UPF0229 protein YeaH [yeaH]. 1 419 34.664 T 14-10-2018 IPR006698 Uncharacterised protein family UPF0229 LH59_03455 ec5e11fce38273380ea0fbccdfb4199e 419 Pfam PF04285 Protein of unknown function (DUF444) 4 417 4.0E-167 T 14-10-2018 IPR006698 Uncharacterised protein family UPF0229 LH59_17720 9931a38b60055429e667df446c0e587a 229 Pfam PF07302 AroM protein 9 228 3.7E-61 T 14-10-2018 IPR010843 Uncharacterised protein family AroM LH59_17720 9931a38b60055429e667df446c0e587a 229 ProDom PD037589 AROM ARO OPERON REGULATED BY AROR BIOSYNTHESIS TRANSCRIPTION AMINO AROMATIC 8 227 6.0E-20 T 14-10-2018 IPR010843 Uncharacterised protein family AroM LH59_16295 75043c9de26dd8eb27b6433e76709ba7 290 Gene3D G3DSA:3.80.10.10 42 288 1.2E-16 T 14-10-2018 IPR032675 Leucine-rich repeat domain superfamily LH59_16295 75043c9de26dd8eb27b6433e76709ba7 290 SUPERFAMILY SSF52058 63 269 8.5E-13 T 14-10-2018 LH59_27530 c2b56e779bef8b445205fcca8638c920 258 Pfam PF04116 Fatty acid hydroxylase superfamily 105 234 1.5E-21 T 14-10-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 LH59_26045 b5eb1216dcffac52c8f5b4cb4ae966c9 444 Pfam PF11299 Protein of unknown function (DUF3100) 31 270 3.6E-87 T 14-10-2018 IPR021450 Protein of unknown function DUF3100 LH59_09325 dfaa1b76f004fba76cbec44616b9fddd 152 SMART SM00116 78 125 0.015 T 14-10-2018 IPR000644 CBS domain LH59_09325 dfaa1b76f004fba76cbec44616b9fddd 152 SMART SM00116 14 61 1.3E-4 T 14-10-2018 IPR000644 CBS domain LH59_09325 dfaa1b76f004fba76cbec44616b9fddd 152 Gene3D G3DSA:3.10.580.10 1 141 9.8E-33 T 14-10-2018 LH59_09325 dfaa1b76f004fba76cbec44616b9fddd 152 SUPERFAMILY SSF54631 2 126 4.55E-28 T 14-10-2018 LH59_09325 dfaa1b76f004fba76cbec44616b9fddd 152 Pfam PF00571 CBS domain 72 125 2.1E-8 T 14-10-2018 IPR000644 CBS domain LH59_09325 dfaa1b76f004fba76cbec44616b9fddd 152 Pfam PF00571 CBS domain 16 60 1.2E-7 T 14-10-2018 IPR000644 CBS domain LH59_17495 e2fdcb10f115fbb9412736adf816f98b 334 Pfam PF03864 Phage major capsid protein E 12 332 2.5E-74 T 14-10-2018 IPR005564 Major capsid protein GpE LH59_18770 720379459b3e0beb6b5b74b63e64b9bc 203 Pfam PF01810 LysE type translocator 14 188 6.2E-7 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 LH59_01680 567ebbb37cb4a0e563f4249956b96162 432 Pfam PF11737 Protein of unknown function (DUF3300) 30 265 2.3E-89 T 14-10-2018 IPR021728 Protein of unknown function DUF3300 LH59_15850 29055fedb26352d44cc3075a89bcc667 171 SUPERFAMILY SSF55729 6 171 3.55E-36 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_15850 29055fedb26352d44cc3075a89bcc667 171 Pfam PF00583 Acetyltransferase (GNAT) family 51 147 8.3E-20 T 14-10-2018 IPR000182 GNAT domain LH59_15850 29055fedb26352d44cc3075a89bcc667 171 Gene3D G3DSA:3.40.630.30 6 169 5.4E-42 T 14-10-2018 LH59_26325 57e3a6f3b7adfd60a2e627c512e492bf 122 Gene3D G3DSA:1.10.260.40 1 42 4.4E-9 T 14-10-2018 LH59_13060 13a113b0e520b5da95a750408a4caa1d 288 TIGRFAM TIGR00163 PS_decarb: phosphatidylserine decarboxylase 51 285 3.3E-77 T 14-10-2018 IPR033177 Phosphatidylserine decarboxylase GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 LH59_13060 13a113b0e520b5da95a750408a4caa1d 288 Pfam PF02666 Phosphatidylserine decarboxylase 65 284 4.7E-62 T 14-10-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 LH59_13060 13a113b0e520b5da95a750408a4caa1d 288 Hamap MF_00662 Phosphatidylserine decarboxylase proenzyme [psd]. 12 287 47.644 T 14-10-2018 IPR033178 Phosphatidylserine decarboxylase, prokaryotic type 1 GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 LH59_20735 4494598149985bf141d77111d95142b0 545 Pfam PF03929 PepSY-associated TM region 12 379 8.9E-61 T 14-10-2018 IPR005625 PepSY-associated TM protein LH59_23025 6bcdb217cd0ac445f8677e1b822cd40b 520 Pfam PF08811 Protein of unknown function (DUF1800) 26 517 1.6E-86 T 14-10-2018 IPR014917 Protein of unknown function DUF1800 LH59_15465 f3107397f7f9997bc8761505687e27b0 227 Gene3D G3DSA:1.25.40.10 9 113 1.3E-7 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_15465 f3107397f7f9997bc8761505687e27b0 227 SUPERFAMILY SSF48452 29 96 8.86E-9 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 LH59_00050 e23ea2c68f7ef207b8bd610cdf0ad975 151 Pfam PF07681 DoxX 30 103 6.5E-13 T 14-10-2018 IPR032808 DoxX family LH59_21385 b008a9ea25c0fa7f18409cfcd752fd15 422 Pfam PF04966 Carbohydrate-selective porin, OprB family 60 422 5.3E-96 T 14-10-2018 IPR007049 Carbohydrate-selective porin OprB GO:0008643|GO:0015288|GO:0016021 LH59_21385 b008a9ea25c0fa7f18409cfcd752fd15 422 Gene3D G3DSA:2.40.160.180 17 422 1.4E-130 T 14-10-2018 IPR038673 Carbohydrate-selective porin OprB superfamily LH59_02760 049920f2ab7efbdff36ed6e527e3dfbc 296 Hamap MF_01805 Segregation and condensation protein A [scpA]. 54 288 20.843 T 14-10-2018 IPR003768 Segregation and condensation protein A LH59_02760 049920f2ab7efbdff36ed6e527e3dfbc 296 Pfam PF02616 Segregation and condensation protein ScpA 71 286 8.1E-33 T 14-10-2018 IPR003768 Segregation and condensation protein A LH59_13005 1788af4dd8fbee85ed1c27859a8b881f 125 Pfam PF04241 Protein of unknown function (DUF423) 20 106 1.0E-27 T 14-10-2018 IPR006696 Protein of unknown function DUF423 LH59_06285 fa4eb8fbc68c3bb9af8e6886a2867ce1 198 Pfam PF02361 Cobalt transport protein 11 196 1.3E-14 T 14-10-2018 IPR003339 ABC/ECF transporter, transmembrane component LH59_25365 86e0df16e3a5600f8516f7bbcc3718ee 280 Pfam PF01578 Cytochrome C assembly protein 60 276 2.0E-23 T 14-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 LH59_02265 5583bf949f72e3f18586045f760ad655 304 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 291 1.0E-39 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_10885 b80c91f8671d68dcc14405a40daa99ad 354 Pfam PF13387 Domain of unknown function (DUF4105) 140 290 1.2E-41 T 14-10-2018 IPR025178 Domain of unknown function DUF4105 LH59_09650 5638d948f0610afd20b71a2a4233c412 144 Pfam PF17274 Family of unknown function (DUF5339) 75 142 1.4E-8 T 14-10-2018 IPR020493 Uncharacterised protein family HI0310 LH59_13645 e9e25435a6ceab8e83ca1dba6babe714 125 Pfam PF01042 Endoribonuclease L-PSP 15 121 4.3E-28 T 14-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 LH59_13645 e9e25435a6ceab8e83ca1dba6babe714 125 Gene3D G3DSA:3.30.1330.40 4 121 6.9E-37 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 LH59_13645 e9e25435a6ceab8e83ca1dba6babe714 125 SUPERFAMILY SSF55298 13 124 1.1E-35 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 LH59_14160 6a0724795f56b78ac8fa5bd00b9c5ddc 113 SUPERFAMILY SSF50249 5 92 6.0E-7 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold LH59_17650 19e7addb4406ce5c0b399d0a8222cbb3 220 Gene3D G3DSA:1.10.530.10 2 152 1.4E-7 T 14-10-2018 LH59_10025 dca6184bd2ab1764e6df353b9ab86d06 86 SUPERFAMILY SSF47336 1 83 1.44E-14 T 14-10-2018 IPR036736 ACP-like superfamily LH59_10025 dca6184bd2ab1764e6df353b9ab86d06 86 Gene3D G3DSA:1.10.1200.10 3 86 8.9E-21 T 14-10-2018 IPR036736 ACP-like superfamily LH59_10025 dca6184bd2ab1764e6df353b9ab86d06 86 Pfam PF00550 Phosphopantetheine attachment site 7 80 2.6E-10 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain LH59_15420 e34b5bc6d054913fe81cbe4d1571638c 328 Pfam PF13503 Domain of unknown function (DUF4123) 34 160 6.2E-11 T 14-10-2018 IPR025391 Domain of unknown function DUF4123 LH59_19825 7feff44b23de7afd221980fa78200acf 146 Pfam PF07811 TadE-like protein 2 32 3.7E-5 T 14-10-2018 IPR012495 TadE-like LH59_07020 1da498fe7026115d02e9416a16e18908 107 Pfam PF11804 Protein of unknown function (DUF3325) 3 102 4.7E-34 T 14-10-2018 IPR021762 Protein of unknown function DUF3325 LH59_00770 4e1661b21d8829a0b6315d7cc01ca80e 490 Pfam PF06097 Bacterial protein of unknown function (DUF945) 1 475 4.0E-109 T 14-10-2018 IPR010352 Protein of unknown function DUF945 LH59_07305 5043d2725d44e4f0dd58a931979f75ff 104 Pfam PF06305 Lipopolysaccharide assembly protein A domain 22 86 3.3E-16 T 14-10-2018 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 LH59_27630 859003926d0308b8d6fb8a72b3bfb7ba 394 SUPERFAMILY SSF103473 13 392 8.37E-57 T 14-10-2018 IPR036259 MFS transporter superfamily LH59_27630 859003926d0308b8d6fb8a72b3bfb7ba 394 Pfam PF07690 Major Facilitator Superfamily 48 354 2.1E-36 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 LH59_27630 859003926d0308b8d6fb8a72b3bfb7ba 394 Gene3D G3DSA:1.20.1250.20 6 391 6.1E-74 T 14-10-2018 LH59_28090 f1778ed50765636bea82adb7c8b7ce0a 195 Gene3D G3DSA:2.60.120.10 47 190 1.1E-23 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_28090 f1778ed50765636bea82adb7c8b7ce0a 195 SUPERFAMILY SSF51182 11 190 1.22E-37 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_07150 5fc56ebf56ab32523fbf7c5dc77aa748 379 Gene3D G3DSA:3.40.630.30 175 328 1.6E-8 T 14-10-2018 LH59_07150 5fc56ebf56ab32523fbf7c5dc77aa748 379 SUPERFAMILY SSF55729 177 350 5.83E-37 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase LH59_07150 5fc56ebf56ab32523fbf7c5dc77aa748 379 Pfam PF04339 Peptidogalycan biosysnthesis/recognition 13 375 1.5E-153 T 14-10-2018 IPR007434 Peptidogalycan biosysnthesis/recognition LH59_19480 e3c6f9ff8ac3c615a3d58b1247ed44e7 200 SUPERFAMILY SSF52317 58 198 4.3E-5 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_18050 dc17afb976d20ac836157a258c3e643c 257 Pfam PF01925 Sulfite exporter TauE/SafE 10 251 5.0E-45 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 LH59_06340 d3470c94f6bd9d87208c1611083fbfbb 295 Pfam PF02653 Branched-chain amino acid transport system / permease component 17 283 6.5E-40 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_09045 67a593754c0e2a27262db994b412733b 134 SUPERFAMILY SSF51182 1 128 6.68E-22 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily LH59_09045 67a593754c0e2a27262db994b412733b 134 Hamap MF_01255 L-ectoine synthase [ectC]. 1 128 39.389 T 14-10-2018 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108 LH59_09045 67a593754c0e2a27262db994b412733b 134 Pfam PF06339 Ectoine synthase 1 126 1.2E-56 T 14-10-2018 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108 LH59_09045 67a593754c0e2a27262db994b412733b 134 ProDom PD080544 SYNTHASE 4.2.1.- LYASE L-ECTOINE DEHYDRATASE N-ACETYLDIAMINOBUTYRATE ECTOINE ENZYME SYNTHASE:ECTOINE ECTC 1 118 8.0E-63 T 14-10-2018 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108 LH59_09045 67a593754c0e2a27262db994b412733b 134 Gene3D G3DSA:2.60.120.10 1 116 3.8E-45 T 14-10-2018 IPR014710 RmlC-like jelly roll fold LH59_27680 83d535c0b81b09d5e21c6b8d0ef33543 692 Pfam PF05140 ResB-like family 26 680 1.1E-155 T 14-10-2018 IPR007816 ResB-like domain LH59_06175 d8106daf666408def6dcd3b08ca62693 109 PIRSF PIRSF019883 1 106 4.9E-43 T 14-10-2018 IPR016768 Uncharacterised conserved protein UCP019883, membrane LH59_06175 d8106daf666408def6dcd3b08ca62693 109 Pfam PF10993 Protein of unknown function (DUF2818) 6 102 1.7E-34 T 14-10-2018 IPR016768 Uncharacterised conserved protein UCP019883, membrane LH59_22950 388f898d5cffb8f4782a4e211ec6065c 229 Pfam PF07077 Protein of unknown function (DUF1345) 54 220 4.8E-53 T 14-10-2018 IPR009781 Protein of unknown function DUF1345 LH59_10850 e34383087c022a9117ed32285cd6039b 127 Pfam PF13788 Domain of unknown function (DUF4180) 13 122 2.6E-40 T 14-10-2018 IPR025438 Domain of unknown function DUF4180 LH59_07085 95f951a5b02c071f2ee6fa8b35ee925b 281 Pfam PF03239 Iron permease FTR1 family 3 263 1.7E-22 T 14-10-2018 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0016020|GO:0033573|GO:0034755 LH59_08890 51e5a9b078be2c409dfb2d71b40fd6fc 326 ProDom PD024016 LIPOPOLYSACCHARIDE BIOSYNTHESIS CORE RFAZ WAAZ 86 315 2.0E-10 T 14-10-2018 LH59_05080 95c26859741964b14c77b0d377414f27 292 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 28 261 2.6E-50 T 14-10-2018 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related LH59_04825 6cbf056fcc310b720fad36ccec5f6b23 346 Pfam PF02653 Branched-chain amino acid transport system / permease component 13 330 2.5E-15 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_15110 b359abd849cd15a8221be9dd7ccbd087 277 Pfam PF02653 Branched-chain amino acid transport system / permease component 4 251 1.1E-36 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_15355 d10b17509cf101cb6a0d16180afe7e17 479 Pfam PF02515 CoA-transferase family III 220 411 2.0E-45 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 LH59_15355 d10b17509cf101cb6a0d16180afe7e17 479 SUPERFAMILY SSF89796 217 436 6.28E-56 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily LH59_15355 d10b17509cf101cb6a0d16180afe7e17 479 Gene3D G3DSA:3.40.50.10540 215 474 2.5E-55 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily LH59_15355 d10b17509cf101cb6a0d16180afe7e17 479 SUPERFAMILY SSF89796 35 208 1.44E-19 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily LH59_21400 df10077149e3bcf38c36ceb637e9f960 395 Pfam PF02653 Branched-chain amino acid transport system / permease component 58 384 8.0E-48 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_17730 3dd6d57acc2053b4545ee5c20d2328e9 234 SUPERFAMILY SSF52317 3 216 2.5E-39 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_17730 3dd6d57acc2053b4545ee5c20d2328e9 234 Gene3D G3DSA:3.40.50.880 1 228 1.4E-58 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_17730 3dd6d57acc2053b4545ee5c20d2328e9 234 Pfam PF03575 Peptidase family S51 3 207 2.8E-55 T 14-10-2018 IPR005320 Peptidase S51 GO:0006508|GO:0008236 LH59_00775 367846dfa77d974564bece79c53ad603 472 Pfam PF06097 Bacterial protein of unknown function (DUF945) 2 459 8.5E-76 T 14-10-2018 IPR010352 Protein of unknown function DUF945 LH59_02450 5fe12fe6c7ab2fcd1c11752c4ce1c591 302 Pfam PF05275 Copper resistance protein B precursor (CopB) 97 302 2.6E-80 T 14-10-2018 IPR007939 Copper resistance B precursor GO:0005507|GO:0006878|GO:0009279 LH59_25830 0cdeb7923deeb47a37d276502c0cac29 424 Pfam PF02653 Branched-chain amino acid transport system / permease component 37 303 4.9E-27 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_08450 0073902ceed502760ff5227816f85c97 407 Pfam PF04143 Sulphur transport 62 385 3.6E-71 T 14-10-2018 IPR007272 Sulphur transport domain LH59_24920 88f216f3cb20286583db1c0889671065 401 Pfam PF01757 Acyltransferase family 3 331 3.1E-16 T 14-10-2018 IPR002656 Acyltransferase 3 GO:0016747 LH59_24710 2c34082b439ba09468c8605387347694 449 Pfam PF03023 MviN-like protein 44 442 4.6E-34 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ LH59_04940 e26787ebfcc2ea19b262350bbce9663c 125 SUPERFAMILY SSF88723 1 119 5.05E-14 T 14-10-2018 IPR029060 PIN-like domain superfamily LH59_04940 e26787ebfcc2ea19b262350bbce9663c 125 Gene3D G3DSA:3.40.50.1010 1 121 4.4E-11 T 14-10-2018 LH59_04940 e26787ebfcc2ea19b262350bbce9663c 125 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 119 9.645 T 14-10-2018 IPR022907 VapC family GO:0004540 LH59_09390 e5fd646ccd24b8db50a8bf814a6d52fa 1584 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 1267 1372 1.2E-26 T 14-10-2018 IPR010221 VCBS repeat LH59_09390 e5fd646ccd24b8db50a8bf814a6d52fa 1584 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 1058 1155 6.4E-33 T 14-10-2018 IPR010221 VCBS repeat LH59_09390 e5fd646ccd24b8db50a8bf814a6d52fa 1584 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 633 729 2.7E-31 T 14-10-2018 IPR010221 VCBS repeat LH59_09390 e5fd646ccd24b8db50a8bf814a6d52fa 1584 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 521 615 2.4E-26 T 14-10-2018 IPR010221 VCBS repeat LH59_09390 e5fd646ccd24b8db50a8bf814a6d52fa 1584 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 846 942 1.6E-31 T 14-10-2018 IPR010221 VCBS repeat LH59_09390 e5fd646ccd24b8db50a8bf814a6d52fa 1584 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 1480 1520 5.0E-9 T 14-10-2018 IPR010221 VCBS repeat LH59_09390 e5fd646ccd24b8db50a8bf814a6d52fa 1584 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 1378 1475 8.7E-34 T 14-10-2018 IPR010221 VCBS repeat LH59_09390 e5fd646ccd24b8db50a8bf814a6d52fa 1584 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 311 408 2.4E-32 T 14-10-2018 IPR010221 VCBS repeat LH59_09390 e5fd646ccd24b8db50a8bf814a6d52fa 1584 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 734 839 4.9E-27 T 14-10-2018 IPR010221 VCBS repeat LH59_09390 e5fd646ccd24b8db50a8bf814a6d52fa 1584 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 1160 1262 1.0E-26 T 14-10-2018 IPR010221 VCBS repeat LH59_09390 e5fd646ccd24b8db50a8bf814a6d52fa 1584 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 225 305 1.4E-6 T 14-10-2018 IPR010221 VCBS repeat LH59_09390 e5fd646ccd24b8db50a8bf814a6d52fa 1584 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 947 1052 4.2E-27 T 14-10-2018 IPR010221 VCBS repeat LH59_09390 e5fd646ccd24b8db50a8bf814a6d52fa 1584 TIGRFAM TIGR01965 VCBS_repeat: VCBS repeat 413 515 2.0E-27 T 14-10-2018 IPR010221 VCBS repeat LH59_17465 e1fe01a83143fc165fca0d89d413a4e1 103 Pfam PF08809 Phage related hypothetical protein (DUF1799) 23 97 8.5E-9 T 14-10-2018 IPR014915 Bacteriophage TLS, TfmB LH59_21270 3a636e3a03363a9f2da928e249da8e90 489 Pfam PF13785 Domain of unknown function (DUF4178) 57 194 5.2E-19 T 14-10-2018 IPR025235 Domain of unknown function DUF4178 LH59_21270 3a636e3a03363a9f2da928e249da8e90 489 Pfam PF13785 Domain of unknown function (DUF4178) 278 413 9.5E-16 T 14-10-2018 IPR025235 Domain of unknown function DUF4178 LH59_21810 eb582dcc98c817b4b3b7655cf16ae075 381 Pfam PF04116 Fatty acid hydroxylase superfamily 213 346 5.6E-28 T 14-10-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 LH59_16085 c4b544ef05c8605e1772d48f9be32565 73 Pfam PF00872 Transposase, Mutator family 2 41 3.8E-8 T 14-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 LH59_19475 2bb74d12a4755a2ef4c9d53a00780b9f 216 SUPERFAMILY SSF52317 41 212 4.88E-6 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like LH59_01700 8b8331a7f3ac39df4141d736ee8bcb9f 337 Pfam PF04116 Fatty acid hydroxylase superfamily 135 274 1.6E-30 T 14-10-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 LH59_09305 54785695e5a0095dea8e583886f9e181 323 Pfam PF00482 Type II secretion system (T2SS), protein F 185 310 1.9E-16 T 14-10-2018 IPR018076 Type II secretion system F domain LH59_19375 df508c66af1d66ccbc2cb0a984626ffd 319 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 18 293 1.4E-10 T 14-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD LH59_21305 25d9a11fbe7d8a4e3254236efc70ff86 296 Pfam PF02653 Branched-chain amino acid transport system / permease component 9 279 1.7E-31 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_22670 18bae1e1bed2eccd894a3f0446621fd6 241 Gene3D G3DSA:2.40.360.20 82 241 1.6E-5 T 14-10-2018 LH59_27615 44f2725fff5fbf3549c72d7fe8aaa855 101 Pfam PF13663 Domain of unknown function (DUF4148) 1 56 2.2E-12 T 14-10-2018 IPR025421 Protein of unknown function DUF4148 LH59_27615 44f2725fff5fbf3549c72d7fe8aaa855 101 Pfam PF13663 Domain of unknown function (DUF4148) 61 97 5.5E-10 T 14-10-2018 IPR025421 Protein of unknown function DUF4148 LH59_00230 b1e9fe388dfb1f34430deee008a9fc1b 316 Pfam PF02653 Branched-chain amino acid transport system / permease component 15 293 1.5E-34 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_27030 dd7a38314b82269736500fa1f615d767 328 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 1 323 5.4E-102 T 14-10-2018 IPR007296 Domain of unknown function DUF403 LH59_17455 7418fd59e83fe17eeec65b0635126d2a 113 Pfam PF05939 Phage minor tail protein 5 109 3.1E-33 T 14-10-2018 IPR010265 Bacteriophage lambda, GpM, minor tail LH59_00645 48f5a92c10db22bf39e08418a1e52326 114 Pfam PF08895 Domain of unknown function (DUF1840) 1 108 1.5E-27 T 14-10-2018 IPR014991 Protein of unknown function DUF1840 LH59_00235 6ad175c9ccd1ed9a932454c3c31a5d95 357 Pfam PF02653 Branched-chain amino acid transport system / permease component 60 342 4.9E-37 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_14615 dde9a50f364e1daca4f1379412e7a9ae 116 Pfam PF11804 Protein of unknown function (DUF3325) 11 108 9.6E-31 T 14-10-2018 IPR021762 Protein of unknown function DUF3325 LH59_19745 8118a85010828f0ae2104b9849053fbd 400 Pfam PF11062 Protein of unknown function (DUF2863) 5 399 1.5E-170 T 14-10-2018 IPR021292 Protein of unknown function DUF2863 LH59_08275 7a84adf95147ce084b6cec58fb8581c4 605 Pfam PF13687 Domain of unknown function (DUF4153) 161 390 3.2E-16 T 14-10-2018 IPR025291 Protein of unknown function DUF4153 LH59_07210 75ae006fed2d03b328e60288b70f9346 332 Pfam PF16822 SGNH hydrolase-like domain, acetyltransferase AlgX 39 298 2.3E-68 T 14-10-2018 IPR031811 AlgX/AlgJ, SGNH hydrolase-like domain LH59_13480 d35536ec38f2df59e3b5bda904000685 135 Pfam PF07681 DoxX 17 98 3.6E-15 T 14-10-2018 IPR032808 DoxX family LH59_24990 d20dd667750f25be832ae9201c774e07 375 Pfam PF12698 ABC-2 family transporter protein 26 364 3.0E-34 T 14-10-2018 LH59_02400 0156ce265be510179c8c039453dc7c30 212 Pfam PF03458 UPF0126 domain 13 86 1.3E-17 T 14-10-2018 IPR005115 Uncharacterised domain UPF0126 LH59_02400 0156ce265be510179c8c039453dc7c30 212 Pfam PF03458 UPF0126 domain 98 169 5.2E-20 T 14-10-2018 IPR005115 Uncharacterised domain UPF0126 LH59_01415 67c42772093a44f921e5c8fb28a8f63f 332 ProDom PD024016 LIPOPOLYSACCHARIDE BIOSYNTHESIS CORE RFAZ WAAZ 67 309 5.0E-5 T 14-10-2018 LH59_09885 6a828b1612916a7c1a284f00432257d9 391 Pfam PF03929 PepSY-associated TM region 13 365 3.5E-61 T 14-10-2018 IPR005625 PepSY-associated TM protein LH59_21730 f2f718c070a033c954f124f7280e8277 254 Pfam PF01925 Sulfite exporter TauE/SafE 10 242 2.6E-14 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 LH59_12500 4da950f70b162580522370bc59e993ba 198 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 28 157 3.6E-21 T 14-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ LH59_15235 40b29df80d81135774971b67717de601 288 Pfam PF01618 MotA/TolQ/ExbB proton channel family 102 221 2.4E-19 T 14-10-2018 IPR002898 MotA/TolQ/ExbB proton channel LH59_09455 8c40b2f9f4ad1069f4bbe07814d2449b 217 SUPERFAMILY SSF51366 3 211 4.08E-56 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 LH59_09455 8c40b2f9f4ad1069f4bbe07814d2449b 217 Gene3D G3DSA:3.20.20.70 1 217 6.2E-65 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 LH59_09455 8c40b2f9f4ad1069f4bbe07814d2449b 217 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 5 208 3.5E-41 T 14-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 LH59_09455 8c40b2f9f4ad1069f4bbe07814d2449b 217 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 3 213 39.487 T 14-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 LH59_03720 f3c652469a70a84d2689a2183a1d19d2 134 Pfam PF03788 LrgA family 30 121 1.7E-23 T 14-10-2018 IPR005538 LrgA/CidA family GO:0016021 LH59_21115 597193a48e7a62a7665377b01403e808 324 Pfam PF00122 E1-E2 ATPase 172 239 8.0E-9 T 14-10-2018 LH59_27440 a9cb4f99e9509a9fd8d07e3d1543fa71 279 Pfam PF01061 ABC-2 type transporter 30 237 1.4E-15 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 LH59_15455 fe8c712f1998bc371d70ea7d6dd45d70 496 TIGRFAM TIGR03355 VI_chp_2: type VI secretion protein, EvpB/VC_A0108 family 19 490 6.2E-218 T 14-10-2018 IPR010269 Type VI secretion protein, EvpB/VC_A0108, tail sheath LH59_15455 fe8c712f1998bc371d70ea7d6dd45d70 496 Pfam PF05943 Type VI secretion protein, EvpB/VC_A0108, tail sheath 68 490 5.8E-191 T 14-10-2018 IPR010269 Type VI secretion protein, EvpB/VC_A0108, tail sheath LH59_11970 e38ab55c811140c1d79cf530c2042172 135 Pfam PF07681 DoxX 9 89 5.0E-18 T 14-10-2018 IPR032808 DoxX family LH59_01785 187b1ee3081c677bdcf2549fec5fc293 88 Pfam PF11142 Protein of unknown function (DUF2917) 12 70 2.9E-14 T 14-10-2018 IPR021317 Protein of unknown function DUF2917 LH59_05385 3799ce93c9b71200806951b6ec4f8333 423 Pfam PF04932 O-Antigen ligase 189 342 1.5E-22 T 14-10-2018 IPR007016 O-antigen ligase-related LH59_18810 1afe48f8191b702cdc1ca95c957fa137 176 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 30 160 4.5E-20 T 14-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ LH59_04080 2f89901aa0f0115fe530918e4810b170 163 Pfam PF05258 Protein of unknown function (DUF721) 34 98 4.2E-7 T 14-10-2018 IPR007922 Protein of unknown function DUF721/UPF0232 LH59_05815 36de4901c29a76393522540c30435cb3 331 SUPERFAMILY SSF53850 45 312 2.01E-23 T 14-10-2018 LH59_05815 36de4901c29a76393522540c30435cb3 331 Gene3D G3DSA:3.40.190.10 31 132 4.0E-11 T 14-10-2018 LH59_05815 36de4901c29a76393522540c30435cb3 331 Gene3D G3DSA:3.40.190.10 133 330 3.3E-30 T 14-10-2018 LH59_05815 36de4901c29a76393522540c30435cb3 331 PIRSF PIRSF027386 10 331 7.7E-65 T 14-10-2018 IPR027024 ABC-type uncharacterised transport system, substrate-binding component, TM0202 type LH59_27960 f6e63db00ecb2a8193aae166271d14ab 442 Gene3D G3DSA:1.10.510.10 22 194 3.3E-8 T 14-10-2018 LH59_27960 f6e63db00ecb2a8193aae166271d14ab 442 SUPERFAMILY SSF56112 34 189 1.4E-8 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily LH59_10895 f6bea7bca7040cabcf12df433ccbaaa1 216 Pfam PF06912 Protein of unknown function (DUF1275) 3 205 4.6E-30 T 14-10-2018 IPR010699 Protein of unknown function DUF1275 LH59_03650 41254648b2e677ea88c3771d918fc92d 529 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 71 233 4.4E-18 T 14-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like LH59_17725 2baafec893abe8daf3fd4f5a30d997c8 309 Pfam PF06675 Protein of unknown function (DUF1177) 39 302 7.4E-115 T 14-10-2018 IPR009561 Protein of unknown function DUF1177 LH59_02755 8e5e0b373a4c31fe63dd15b34097d234 62 Pfam PF11943 Protein of unknown function (DUF3460) 4 60 2.3E-28 T 14-10-2018 IPR021853 Protein of unknown function DUF3460 LH59_08520 45beb3be3d8d76fb83608dabd00e01b1 329 Pfam PF01618 MotA/TolQ/ExbB proton channel family 170 287 9.1E-34 T 14-10-2018 IPR002898 MotA/TolQ/ExbB proton channel LH59_16470 fec8675ba2cfc849f2e7b482e4bdae0c 331 Pfam PF13387 Domain of unknown function (DUF4105) 117 267 1.2E-39 T 14-10-2018 IPR025178 Domain of unknown function DUF4105 LH59_10195 547386267180d2edf153d729513c8c02 210 PIRSF PIRSF006324 1 209 6.6E-46 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 LH59_10195 547386267180d2edf153d729513c8c02 210 Pfam PF01810 LysE type translocator 17 207 1.7E-30 T 14-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 LH59_06480 58d9533a420c960fca22d9cdc19effbf 199 Pfam PF02620 Uncharacterized ACR, COG1399 63 196 1.0E-16 T 14-10-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD LH59_26980 756722c7e0a97a10be0e0cc9102fb7f7 675 Pfam PF13332 Haemagluttinin repeat 1 53 2.8E-10 T 14-10-2018 IPR025157 Hemagglutinin repeat LH59_11960 73229e50fb796eb5aa1c7936b07c2a08 430 Pfam PF12779 YXWGXW repeat (2 copies) 107 127 0.097 T 14-10-2018 IPR024447 YXWGXW repeat LH59_11960 73229e50fb796eb5aa1c7936b07c2a08 430 Pfam PF12779 YXWGXW repeat (2 copies) 74 99 0.011 T 14-10-2018 IPR024447 YXWGXW repeat LH59_22385 cca82bf1f06159914dc7e43cad88868c 296 Pfam PF06007 Phosphonate metabolism protein PhnJ 16 287 1.5E-146 T 14-10-2018 IPR010306 Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase GO:0016829|GO:0019700|GO:0051539 KEGG: 00440+4.7.1.1|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 LH59_22385 cca82bf1f06159914dc7e43cad88868c 296 PIRSF PIRSF011468 8 296 5.0E-160 T 14-10-2018 IPR010306 Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase GO:0016829|GO:0019700|GO:0051539 KEGG: 00440+4.7.1.1|MetaCyc: PWY-7399|MetaCyc: PWY-7805|MetaCyc: PWY-7807 LH59_15380 b2ff2fa6d076455f2a59945c9329576f 1099 Pfam PF05650 Domain of unknown function (DUF802) 383 435 1.8E-15 T 14-10-2018 IPR008520 Domain of unknown function DUF802 LH59_15380 b2ff2fa6d076455f2a59945c9329576f 1099 Pfam PF05650 Domain of unknown function (DUF802) 329 380 1.4E-18 T 14-10-2018 IPR008520 Domain of unknown function DUF802 LH59_15380 b2ff2fa6d076455f2a59945c9329576f 1099 Pfam PF05650 Domain of unknown function (DUF802) 776 828 2.4E-12 T 14-10-2018 IPR008520 Domain of unknown function DUF802 LH59_15380 b2ff2fa6d076455f2a59945c9329576f 1099 Pfam PF05650 Domain of unknown function (DUF802) 514 566 9.1E-15 T 14-10-2018 IPR008520 Domain of unknown function DUF802 LH59_15380 b2ff2fa6d076455f2a59945c9329576f 1099 Pfam PF05650 Domain of unknown function (DUF802) 645 697 1.1E-10 T 14-10-2018 IPR008520 Domain of unknown function DUF802 LH59_03880 04be66467d74d871c00cc17533001be1 501 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 438 1.7E-155 T 14-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane LH59_21465 d673ce06260757d4a875aa4075b5e118 625 Pfam PF02653 Branched-chain amino acid transport system / permease component 349 605 1.7E-29 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_21465 d673ce06260757d4a875aa4075b5e118 625 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 290 1.3E-36 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 LH59_02345 eb32b1789ec08015ba01329dbbb21407 202 Pfam PF14435 SUKH-4 immunity protein 4 144 2.3E-8 T 14-10-2018 IPR025851 SUKH-4 immunity protein LH59_01990 59ecf4c5b72e65002e6c01846032811e 137 Pfam PF03899 ATP synthase I chain 28 121 1.0E-9 T 14-10-2018 IPR005598 ATP synthase protein I LH59_19820 8d7aa81c7e234665a927f154606739d9 144 Pfam PF07811 TadE-like protein 2 42 2.2E-9 T 14-10-2018 IPR012495 TadE-like LH59_02495 6bd87d71a77f641d7ab02bd8a7ed5a96 212 Pfam PF02036 SCP-2 sterol transfer family 18 112 2.6E-10 T 14-10-2018 IPR003033 SCP2 sterol-binding domain LH59_11270 a6e060560f8eabce50e551b7854636a5 64 Pfam PF14070 Putative motility protein 14 62 1.1E-9 T 14-10-2018 IPR025906 Putative motility protein LH59_07990 409673af3f7bffa5e7ee9c93c0fd9e68 200 Pfam PF11136 Protein of unknown function (DUF2889) 14 138 9.1E-45 T 14-10-2018 IPR021312 Protein of unknown function DUF2889 LH59_17745 9f1607c7a3654a19801c2477748f752b 212 Pfam PF09335 SNARE associated Golgi protein 39 163 8.9E-16 T 14-10-2018 IPR032816 SNARE associated Golgi protein LH59_27330 c16555f4c866b5d7ee94b67a781c1b61 233 Pfam PF10997 Alternate to MurJ 129 224 1.7E-16 T 14-10-2018 IPR021260 Lipid II flippase Amj LH59_19830 da2f2ded74f5f7d3d11ac8c693de017d 173 Pfam PF01478 Type IV leader peptidase family 11 120 3.0E-13 T 14-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 LH59_03005 e43c42d8ddf85469babea485d0277402 575 Pfam PF03961 Flagellar Assembly Protein A 111 572 4.0E-112 T 14-10-2018 IPR005646 Flagellar assembly protein A LH59_15515 d73880faf8ec0b2703516a200a20d238 325 Pfam PF13503 Domain of unknown function (DUF4123) 29 164 2.8E-12 T 14-10-2018 IPR025391 Domain of unknown function DUF4123 LH59_01685 d4bca285a276e34e2d80d716504e9d53 291 Pfam PF11453 Protein of unknown function (DUF2950) 34 274 1.5E-64 T 14-10-2018 IPR021556 Protein of unknown function DUF2950 LH59_24230 1a49c1a3dd47ef0acb9427c4238206ea 508 SUPERFAMILY SSF53187 49 493 5.45E-12 T 14-10-2018 LH59_24230 1a49c1a3dd47ef0acb9427c4238206ea 508 Gene3D G3DSA:3.40.630.10 251 496 2.6E-15 T 14-10-2018 LH59_24045 7bef700f7ef36219c393a2169dfa1190 90 Pfam PF02583 Metal-sensitive transcriptional repressor 7 86 6.9E-22 T 14-10-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 LH59_24045 7bef700f7ef36219c393a2169dfa1190 90 Gene3D G3DSA:1.20.58.1000 1 90 2.6E-26 T 14-10-2018 IPR038390 Metal-sensitive transcriptional repressor superfamily LH59_10285 834e548af23e6d30e696ba10ef1d483e 297 Pfam PF13557 Putative MetA-pathway of phenol degradation 65 292 2.6E-60 T 14-10-2018 IPR025737 MetA-pathway of phenol degradation, putative LH59_25765 61ce5e4973d6de16b09e5cf26c6f40bd 373 Pfam PF01594 AI-2E family transporter 14 344 1.2E-38 T 14-10-2018 IPR002549 Transmembrane protein TqsA-like LH59_13335 77898be7b4056961d2810fb92047f7cf 156 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 15 151 1.4E-19 T 14-10-2018 IPR009936 Protein of unknown function DUF1468 LH59_09380 ead5dcfd67c924b7bc9677cfcc43209d 232 Gene3D G3DSA:3.10.620.30 37 231 1.1E-64 T 14-10-2018 LH59_09380 ead5dcfd67c924b7bc9677cfcc43209d 232 Pfam PF06035 Bacterial transglutaminase-like cysteine proteinase BTLCP 77 149 3.5E-10 T 14-10-2018 IPR010319 Transglutaminase-like cysteine peptidase, predicted LH59_05835 bef52c77e202f19ddd3feda57b3bfc4a 147 PIRSF PIRSF015875 1 147 1.3E-41 T 14-10-2018 IPR007418 Protein of unknown function DUF474 LH59_21955 6e75a3bcb9167cf4e1766ceb2dd64234 143 Pfam PF14282 FlxA-like protein 62 131 1.4E-6 T 14-10-2018 IPR025577 FlxA-like protein LH59_14420 fc7de63e71dba5f0019321a5e7f80621 457 SUPERFAMILY SSF50939 150 430 3.53E-7 T 14-10-2018 IPR036278 Sialidase superfamily KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 LH59_23230 ab8963ddf4c4972b8be4053915929040 436 Pfam PF00939 Sodium:sulfate symporter transmembrane region 15 434 2.3E-21 T 14-10-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 LH59_17520 0c8f42b8e8122941aa8e8eb58f28724f 691 Pfam PF05876 Phage terminase large subunit (GpA) 39 619 1.7E-150 T 14-10-2018 IPR008866 Bacteriophage lambda, GpA LH59_24290 41a820e2d4eccf53395502b9a4d43f80 227 Pfam PF07007 Lysozyme inhibitor LprI 23 87 1.2E-8 T 14-10-2018 IPR009739 Lysozyme inhibitor LprI, N-terminal LH59_05205 5e598bb6f18c4d4d1814865462a78277 133 Pfam PF07681 DoxX 11 87 2.0E-17 T 14-10-2018 IPR032808 DoxX family LH59_20995 387f842b114d09e5a6e331b561110653 202 SUPERFAMILY SSF47240 9 93 1.62E-7 T 14-10-2018 IPR009078 Ferritin-like superfamily LH59_08615 d3cefed09738ac40e284f7eb2e763057 843 Pfam PF02687 FtsX-like permease family 747 836 6.3E-8 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 LH59_08615 d3cefed09738ac40e284f7eb2e763057 843 Pfam PF02687 FtsX-like permease family 302 385 1.5E-9 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 LH59_25520 c82468e0e3678cefc8afad191479c6df 467 Pfam PF13644 DKNYY family 48 232 2.0E-8 T 14-10-2018 IPR027375 DKNYY family