locus-tag	class	description
AL504_00070	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AL504_00095	COG1573	uracil-dna glycosylase
AL504_00145	COG1136	(ABC) transporter
AL504_00150	COG0084	hydrolase, TatD family'
AL504_00160	COG0745	RESPONSE REGULATOR receiver
AL504_00165	COG4771	TonB-dependent receptor
AL504_00170	COG4607	ABC-type enterochelin transport system periplasmic component
AL504_00175	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL504_00180	COG4605	iron ion homeostasis
AL504_00185	COG4604	ABC transporter, ATP-binding protein
AL504_00205	COG1595	DNA-templated transcription, initiation
AL504_00235	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL504_00245	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_00260	COG3119	arylsulfatase activity
AL504_00280	COG2304	oxidoreductase activity
AL504_00300	COG0714	Associated with various cellular activities
AL504_00305	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AL504_00345	COG2149	membrane
AL504_00390	COG0277	FAD linked oxidase domain protein
AL504_00405	COG0159	tryptophan synthase activity
AL504_00415	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL504_00420	COG0477	Major facilitator Superfamily
AL504_00425	COG0583	DNA-binding transcription factor activity
AL504_00435	COG0583	DNA-binding transcription factor activity
AL504_00445	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL504_00465	COG0613	PHP domain protein
AL504_00500	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL504_00515	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AL504_00515	COG0047	phosphoribosylformylglycinamidine synthase activity
AL504_00535	COG0745	RESPONSE REGULATOR receiver
AL504_00540	COG0642	Histidine kinase
AL504_00555	COG0583	DNA-binding transcription factor activity
AL504_00570	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AL504_00580	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_00590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL504_00595	COG0583	DNA-binding transcription factor activity
AL504_00600	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_00625	COG0745	RESPONSE REGULATOR receiver
AL504_00630	COG2198	Histidine kinase
AL504_00630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_00630	COG2205	protein histidine kinase activity
AL504_00630	COG0784	Response regulator, receiver
AL504_00635	COG0583	DNA-binding transcription factor activity
AL504_00670	COG1953	Uracil, thiamine, allantoin
AL504_00685	COG0477	Major facilitator Superfamily
AL504_00725	COG0583	DNA-binding transcription factor activity
AL504_00755	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL504_00760	COG3706	GGDEF domain
AL504_00770	COG4774	siderophore transport
AL504_00800	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL504_00815	COG3618	amidohydrolase
AL504_00820	COG0583	DNA-binding transcription factor activity
AL504_00830	COG1960	acyl-CoA dehydrogenase activity
AL504_00840	COG1024	Enoyl-CoA hydratase
AL504_00870	COG4773	Receptor
AL504_00900	COG4774	siderophore transport
AL504_00940	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_00945	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AL504_00950	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_00955	COG0583	DNA-binding transcription factor activity
AL504_00970	COG0747	negative chemotaxis
AL504_00975	COG4608	Belongs to the ABC transporter superfamily
AL504_00985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL504_00990	COG0601	transmembrane transport
AL504_00995	COG2072	flavoprotein involved in K transport
AL504_01005	COG1058	Belongs to the CinA family
AL504_01005	COG1546	Belongs to the CinA family
AL504_01035	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_01040	COG3048	D-serine ammonia-lyase activity
AL504_01070	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL504_01080	COG0583	DNA-binding transcription factor activity
AL504_01100	COG3468	outer membrane autotransporter barrel domain protein
AL504_01115	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AL504_01115	COG0519	Catalyzes the synthesis of GMP from XMP
AL504_01130	COG4264	IucA IucC family
AL504_01145	COG0583	DNA-binding transcription factor activity
AL504_01175	COG0640	Transcriptional regulator
AL504_01180	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
AL504_01205	COG1846	Transcriptional regulator
AL504_01225	COG2207	Transcriptional regulator
AL504_01230	COG4221	oxidoreductase activity
AL504_01245	COG2267	carboxylic ester hydrolase activity
AL504_01250	COG0300	oxidoreductase activity
AL504_01265	COG0402	S-adenosylhomocysteine deaminase activity
AL504_01270	COG2814	Major facilitator Superfamily
AL504_01295	COG2207	Transcriptional regulator
AL504_01340	COG0583	DNA-binding transcription factor activity
AL504_01355	COG0165	Argininosuccinate lyase
AL504_01365	COG0456	acetyltransferase
AL504_01365	COG1214	PFAM Peptidase M22, glycoprotease
AL504_01370	COG0583	DNA-binding transcription factor activity
AL504_01385	COG2814	Major facilitator Superfamily
AL504_01390	COG1830	Aldolase
AL504_01395	COG0667	Aldo Keto reductase
AL504_01400	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL504_01405	COG1129	ABC transporter
AL504_01415	COG1070	Carbohydrate kinase
AL504_01420	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AL504_01460	COG0456	acetyltransferase
AL504_01475	COG1199	ATP-dependent helicase activity
AL504_01490	COG0583	DNA-binding transcription factor activity
AL504_01505	COG0840	transmembrane signaling receptor activity
AL504_01535	COG2203	Gaf domain
AL504_01535	COG3706	GGDEF domain
AL504_01535	COG5001	Diguanylate cyclase
AL504_01535	COG4251	negative regulation of phosphorylation
AL504_01540	COG4149	molybdate abc transporter
AL504_01545	COG1840	ABC-type Fe3 transport system, periplasmic component
AL504_01550	COG3842	ATPase activity
AL504_01555	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL504_01560	COG1522	sequence-specific DNA binding
AL504_01570	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AL504_01580	COG2010	Cytochrome c
AL504_01580	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AL504_01585	COG1335	isochorismatase
AL504_01590	COG2309	aminopeptidase activity
AL504_01595	COG0596	Alpha beta hydrolase
AL504_01605	COG2080	2 iron, 2 sulfur cluster binding
AL504_01610	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AL504_01610	COG2010	Cytochrome c
AL504_01615	COG0477	Major facilitator Superfamily
AL504_01620	COG1846	Transcriptional regulator
AL504_01625	COG2814	Major facilitator Superfamily
AL504_01630	COG4771	TonB-dependent receptor
AL504_01645	COG0583	DNA-binding transcription factor activity
AL504_01660	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL504_01670	COG0583	DNA-binding transcription factor activity
AL504_01675	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AL504_01685	COG0318	PFAM AMP-dependent synthetase and ligase
AL504_01690	COG1960	acyl-CoA dehydrogenase activity
AL504_01695	COG1960	acyl-CoA dehydrogenase activity
AL504_01700	COG0183	Belongs to the thiolase family
AL504_01705	COG1024	Enoyl-CoA hydratase
AL504_01705	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL504_01710	COG0583	DNA-binding transcription factor activity
AL504_01745	COG0148	phosphopyruvate hydratase activity
AL504_01755	COG2733	membrane
AL504_01765	COG0625	glutathione transferase activity
AL504_01775	COG0024	Methionine aminopeptidase
AL504_01925	COG3501	Rhs element vgr protein
AL504_01970	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
AL504_01980	COG2885	chlorophyll binding
AL504_02030	COG3971	2-oxopent-4-enoate hydratase activity
AL504_02035	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL504_02055	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL504_02060	COG1414	Transcriptional regulator
AL504_02070	COG3541	Predicted nucleotidyltransferase
AL504_02075	COG1846	Transcriptional regulator
AL504_02105	COG0456	acetyltransferase
AL504_02115	COG0583	DNA-binding transcription factor activity
AL504_02125	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL504_02135	COG0697	spore germination
AL504_02140	COG2207	Transcriptional regulator
AL504_02145	COG4941	Belongs to the sigma-70 factor family
AL504_02155	COG3795	YCII-related domain
AL504_02160	COG3795	YCII-related domain
AL504_02195	COG2207	Transcriptional regulator
AL504_02210	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AL504_02215	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AL504_02220	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AL504_02225	COG0084	hydrolase, TatD family'
AL504_02240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_02250	COG1126	abc transporter atp-binding protein
AL504_02255	COG0010	Belongs to the arginase family
AL504_02265	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AL504_02275	COG0095	Lipoate-protein ligase
AL504_02290	COG0625	glutathione transferase activity
AL504_02300	COG1522	sequence-specific DNA binding
AL504_02305	COG0386	Belongs to the glutathione peroxidase family
AL504_02310	COG2814	Major facilitator Superfamily
AL504_02335	COG3395	kinase activity
AL504_02340	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AL504_02350	COG0840	transmembrane signaling receptor activity
AL504_02360	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL504_02385	COG0513	Belongs to the DEAD box helicase family
AL504_02390	COG1414	Transcriptional regulator
AL504_02410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL504_02415	COG3468	outer membrane autotransporter barrel domain protein
AL504_02415	COG3210	domain, Protein
AL504_02415	COG3468	outer membrane autotransporter barrel domain protein
AL504_02415	COG3210	domain, Protein
AL504_02440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL504_02445	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AL504_02450	COG4521	taurine ABC transporter
AL504_02470	COG1966	Carbon starvation protein
AL504_02475	COG2879	small protein
AL504_02480	COG0697	spore germination
AL504_02485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL504_02505	COG0783	Belongs to the Dps family
AL504_02520	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL504_02525	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL504_02535	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AL504_02540	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
AL504_02545	COG0745	RESPONSE REGULATOR receiver
AL504_02550	COG5002	protein histidine kinase activity
AL504_02555	COG2070	2-Nitropropane dioxygenase
AL504_02575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL504_02615	COG0583	DNA-binding transcription factor activity
AL504_02630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL504_02635	COG0583	DNA-binding transcription factor activity
AL504_02660	COG2223	nitrite transmembrane transporter activity
AL504_02665	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AL504_02670	COG1140	nitrate reductase beta subunit
AL504_02675	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AL504_02680	COG2181	nitrate reductase activity
AL504_02685	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL504_02690	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AL504_02695	COG0288	reversible hydration of carbon dioxide
AL504_02700	COG1763	Mo-molybdopterin cofactor biosynthetic process
AL504_02705	COG3850	Histidine kinase
AL504_02710	COG2197	response regulator
AL504_02735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_02740	COG1104	cysteine desulfurase activity
AL504_02770	COG1116	anion transmembrane transporter activity
AL504_02775	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL504_02780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL504_02810	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AL504_02825	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL504_02830	COG1802	Transcriptional regulator
AL504_02840	COG4948	Mandelate Racemase Muconate Lactonizing
AL504_02875	COG4774	siderophore transport
AL504_02880	COG1309	transcriptional regulator
AL504_02900	COG0251	oxidation-reduction process
AL504_02925	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AL504_02950	COG0277	FAD linked oxidase domain protein
AL504_02960	COG0765	amino acid transport
AL504_02990	COG0583	DNA-binding transcription factor activity
AL504_03025	COG4774	siderophore transport
AL504_03055	COG4566	intracellular signal transduction
AL504_03060	COG4191	Histidine kinase
AL504_03070	COG1846	Transcriptional regulator
AL504_03080	COG0583	DNA-binding transcription factor activity
AL504_03085	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AL504_03115	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL504_03125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL504_03130	COG2070	2-Nitropropane dioxygenase
AL504_03140	COG0765	amino acid transport
AL504_03145	COG1126	abc transporter atp-binding protein
AL504_03150	COG1595	DNA-templated transcription, initiation
AL504_03155	COG3712	iron ion homeostasis
AL504_03160	COG4774	siderophore transport
AL504_03225	COG4774	siderophore transport
AL504_03255	COG1120	ATPase activity
AL504_03260	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL504_03265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL504_03270	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL504_03310	COG3486	L-lysine 6-monooxygenase (NADPH) activity
AL504_03315	COG1136	(ABC) transporter
AL504_03320	COG0390	transport system, permease component
AL504_03325	COG0586	Pfam SNARE associated Golgi protein
AL504_03340	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AL504_03350	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
AL504_03355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL504_03365	COG0745	RESPONSE REGULATOR receiver
AL504_03370	COG0642	Histidine kinase
AL504_03380	COG1126	abc transporter atp-binding protein
AL504_03385	COG0765	amino acid transport
AL504_03390	COG4597	amino acid ABC transporter
AL504_03400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_03405	COG2188	Transcriptional regulator
AL504_03425	COG2721	sulfolactate sulfo-lyase activity
AL504_03430	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_03455	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AL504_03455	COG0519	Catalyzes the synthesis of GMP from XMP
AL504_03470	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL504_03475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL504_03490	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AL504_03495	COG4208	sulfate ABC transporter
AL504_03510	COG1335	isochorismatase
AL504_03515	COG0583	DNA-binding transcription factor activity
AL504_03525	COG0747	negative chemotaxis
AL504_03530	COG0601	transmembrane transport
AL504_03540	COG0444	Belongs to the ABC transporter superfamily
AL504_03550	COG4771	TonB-dependent receptor
AL504_03555	COG0583	DNA-binding transcription factor activity
AL504_03560	COG0626	cystathionine gamma-synthase activity
AL504_03565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_03570	COG4597	amino acid ABC transporter
AL504_03575	COG0765	amino acid transport
AL504_03580	COG1126	abc transporter atp-binding protein
AL504_03600	COG0583	DNA-binding transcription factor activity
AL504_03605	COG2957	Belongs to the agmatine deiminase family
AL504_03610	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AL504_03615	COG0583	DNA-binding transcription factor activity
AL504_03635	COG2207	Transcriptional regulator
AL504_03650	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AL504_03680	COG0583	DNA-binding transcription factor activity
AL504_03705	COG1733	regulation of RNA biosynthetic process
AL504_03745	COG0579	oxidoreductase
AL504_03770	COG0625	glutathione transferase activity
AL504_03795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_03815	COG3971	2-oxopent-4-enoate hydratase activity
AL504_03840	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AL504_03855	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL504_03875	COG0251	oxidation-reduction process
AL504_03885	COG0747	negative chemotaxis
AL504_03890	COG0601	transmembrane transport
AL504_03900	COG0444	Belongs to the ABC transporter superfamily
AL504_03905	COG4608	Belongs to the ABC transporter superfamily
AL504_03910	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AL504_03920	COG0531	amino acid
AL504_03925	COG2226	methyltransferase
AL504_03940	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AL504_03945	COG0626	cystathionine gamma-synthase activity
AL504_03950	COG0628	permease
AL504_03960	COG0583	DNA-binding transcription factor activity
AL504_03965	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL504_03990	COG3706	GGDEF domain
AL504_04000	COG0789	Transcriptional regulator
AL504_04005	COG3706	GGDEF domain
AL504_04145	COG0667	Aldo Keto reductase
AL504_04150	COG0583	DNA-binding transcription factor activity
AL504_04165	COG2205	protein histidine kinase activity
AL504_04190	COG1253	flavin adenine dinucleotide binding
AL504_04240	COG5001	Diguanylate cyclase
AL504_04240	COG3300	MHYT domain
AL504_04245	COG1289	transmembrane transporter activity
AL504_04255	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL504_04265	COG0693	protein deglycase activity
AL504_04285	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_04315	COG2204	response regulator
AL504_04320	COG2204	response regulator
AL504_04325	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AL504_04345	COG4771	TonB-dependent receptor
AL504_04370	COG1132	(ABC) transporter
AL504_04385	COG2814	Major facilitator Superfamily
AL504_04405	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL504_04410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL504_04435	COG0488	(ABC) transporter
AL504_04445	COG0688	phosphatidylethanolamine metabolic process
AL504_04475	COG1408	metallophosphoesterase
AL504_04485	COG2814	Major facilitator Superfamily
AL504_04495	COG1464	Belongs to the NlpA lipoprotein family
AL504_04500	COG0010	Belongs to the arginase family
AL504_04510	COG2363	Small membrane protein
AL504_04515	COG0697	spore germination
AL504_04525	COG2133	pyrroloquinoline quinone binding
AL504_04530	COG0625	glutathione transferase activity
AL504_04535	COG0583	DNA-binding transcription factor activity
AL504_04545	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AL504_04550	COG1794	racemase activity, acting on amino acids and derivatives
AL504_04555	COG0410	ABC transporter
AL504_04570	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL504_04580	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AL504_04590	COG1653	transport
AL504_04595	COG1175	transmembrane transport
AL504_04600	COG0395	ABC-type sugar transport system, permease component
AL504_04605	COG3842	ATPase activity
AL504_04620	COG2205	protein histidine kinase activity
AL504_04625	COG0745	RESPONSE REGULATOR receiver
AL504_04640	COG3866	Pectate lyase
AL504_04645	COG4783	chaperone-mediated protein folding
AL504_04645	COG1560	Kdo2-lipid A biosynthetic process
AL504_04670	COG0438	transferase activity, transferring glycosyl groups
AL504_04675	COG0457	Tetratricopeptide repeat
AL504_04685	COG0783	Belongs to the Dps family
AL504_04695	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AL504_04715	COG0583	DNA-binding transcription factor activity
AL504_04740	COG1840	ABC-type Fe3 transport system, periplasmic component
AL504_04745	COG4149	molybdate abc transporter
AL504_04750	COG3842	ATPase activity
AL504_04755	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_04760	COG1690	Belongs to the RtcB family
AL504_04765	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AL504_04770	COG1741	Belongs to the pirin family
AL504_04775	COG1741	Belongs to the pirin family
AL504_04780	COG0583	DNA-binding transcription factor activity
AL504_04785	COG2204	response regulator
AL504_04790	COG3852	Histidine kinase
AL504_04800	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AL504_04805	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AL504_04815	COG1960	acyl-CoA dehydrogenase activity
AL504_04825	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AL504_04830	COG1561	YicC-like family, N-terminal region
AL504_04835	COG0833	amino acid
AL504_04840	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AL504_04855	COG0791	NLP P60 protein
AL504_04860	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_04865	COG2863	cytochrome
AL504_04870	COG3258	Cytochrome c
AL504_04875	COG0194	GDP metabolic process
AL504_04880	COG1758	RNA polymerase activity
AL504_04885	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL504_04895	COG1335	isochorismatase
AL504_04900	COG1126	abc transporter atp-binding protein
AL504_04905	COG0765	amino acid transport
AL504_04910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_04930	COG2816	NAD+ diphosphatase activity
AL504_04950	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL504_04960	COG0411	ABC transporter
AL504_04970	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL504_04980	COG4336	lyase activity
AL504_04985	COG0583	DNA-binding transcription factor activity
AL504_05000	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL504_05015	COG0583	DNA-binding transcription factor activity
AL504_05025	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AL504_05030	COG0560	Phosphoserine phosphatase
AL504_05035	COG0583	DNA-binding transcription factor activity
AL504_05040	COG3842	ATPase activity
AL504_05045	COG1178	ABC-type Fe3 transport system permease component
AL504_05055	COG4181	ATPase activity
AL504_05065	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL504_05075	COG0584	glycerophosphoryl diester phosphodiesterase
AL504_05080	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AL504_05090	COG2986	histidine ammonia-lyase
AL504_05100	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AL504_05100	COG0678	peroxiredoxin activity
AL504_05115	COG0789	Transcriptional regulator
AL504_05120	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AL504_05145	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AL504_05150	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AL504_05155	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AL504_05160	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AL504_05165	COG2252	PERMEase
AL504_05175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL504_05180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL504_05210	COG2814	Major facilitator Superfamily
AL504_05215	COG0488	(ABC) transporter
AL504_05220	COG1619	proteins homologs of microcin C7 resistance protein MccF
AL504_05225	COG0590	tRNA wobble adenosine to inosine editing
AL504_05240	COG1320	monovalent cation:proton antiporter activity
AL504_05245	COG2212	antiporter activity
AL504_05250	COG1863	multisubunit Na H antiporter MnhE subunit
AL504_05255	COG0651	ATP synthesis coupled electron transport
AL504_05260	COG1006	Multisubunit Na H antiporter MnhC subunit
AL504_05265	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AL504_05265	COG2111	Na H antiporter
AL504_05305	COG0420	3'-5' exonuclease activity
AL504_05310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL504_05350	COG1960	acyl-CoA dehydrogenase activity
AL504_05355	COG1959	2 iron, 2 sulfur cluster binding
AL504_05360	COG3634	alkyl hydroperoxide reductase activity
AL504_05385	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL504_05390	COG0346	lactoylglutathione lyase activity
AL504_05430	COG0395	ABC-type sugar transport system, permease component
AL504_05440	COG3842	ATPase activity
AL504_05445	COG3842	ATPase activity
AL504_05470	COG2130	NADP-dependent
AL504_05485	COG1131	(ABC) transporter
AL504_05490	COG0842	Transport permease protein
AL504_05505	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AL504_05535	COG1902	pentaerythritol trinitrate reductase activity
AL504_05550	COG0602	queuosine metabolic process
AL504_05555	COG0720	synthase
AL504_05565	COG1289	transmembrane transporter activity
AL504_05575	COG1566	PFAM secretion protein HlyD family protein
AL504_05590	COG0028	Belongs to the TPP enzyme family
AL504_05600	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_05610	COG0400	carboxylic ester hydrolase activity
AL504_05615	COG0833	amino acid
AL504_05630	COG0587	DNA-directed DNA polymerase activity
AL504_05650	COG0667	Aldo Keto reductase
AL504_05685	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_05690	COG0583	DNA-binding transcription factor activity
AL504_05705	COG0765	amino acid transport
AL504_05710	COG0765	amino acid transport
AL504_05715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_05725	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AL504_05780	COG0840	transmembrane signaling receptor activity
AL504_05865	COG2764	glyoxalase bleomycin resistance protein dioxygenase
AL504_05885	COG4774	siderophore transport
AL504_05890	COG2345	Transcriptional regulator
AL504_05900	COG1414	Transcriptional regulator
AL504_05910	COG0477	Major facilitator Superfamily
AL504_05920	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL504_05925	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL504_05935	COG0667	Aldo Keto reductase
AL504_05945	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_05950	COG1309	transcriptional regulator
AL504_05965	COG1683	Conserved Protein
AL504_05985	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL504_05985	COG1024	Enoyl-CoA hydratase
AL504_06000	COG2867	negative regulation of translational initiation
AL504_06005	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AL504_06010	COG3706	GGDEF domain
AL504_06025	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AL504_06025	COG0519	Catalyzes the synthesis of GMP from XMP
AL504_06030	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AL504_06030	COG2169	Transcriptional regulator
AL504_06040	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AL504_06070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL504_06075	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AL504_06080	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL504_06090	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AL504_06095	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL504_06100	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AL504_06105	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL504_06110	COG0750	zinc metalloprotease
AL504_06115	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AL504_06125	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AL504_06130	COG0233	cytoplasmic translational termination
AL504_06135	COG0528	UMP kinase activity
AL504_06140	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AL504_06145	COG0052	Belongs to the universal ribosomal protein uS2 family
AL504_06150	COG0024	Methionine aminopeptidase
AL504_06155	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AL504_06165	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AL504_06170	COG1451	nucleotide metabolic process
AL504_06190	COG0285	dihydrofolate synthase activity
AL504_06200	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_06205	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL504_06225	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AL504_06245	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AL504_06255	COG1677	Flagellar hook-basal body complex protein FliE
AL504_06260	COG1766	The M ring may be actively involved in energy transduction
AL504_06265	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AL504_06290	COG1580	Controls the rotational direction of flagella during chemotaxis
AL504_06325	COG0840	transmembrane signaling receptor activity
AL504_06330	COG0840	transmembrane signaling receptor activity
AL504_06340	COG0840	transmembrane signaling receptor activity
AL504_06345	COG0840	transmembrane signaling receptor activity
AL504_06355	COG1256	bacterial-type flagellum assembly
AL504_06365	COG1706	bacterial-type flagellum-dependent cell motility
AL504_06370	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AL504_06375	COG4786	Flagellar basal body rod
AL504_06380	COG4787	bacterial-type flagellum-dependent cell motility
AL504_06385	COG1749	Flagellar hook protein flgE
AL504_06390	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AL504_06395	COG1558	bacterial-type flagellum-dependent cell motility
AL504_06400	COG1815	bacterial-type flagellum-dependent cell motility
AL504_06410	COG2747	anti-sigma28 factor FlgM
AL504_06435	COG0840	transmembrane signaling receptor activity
AL504_06440	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AL504_06445	COG0745	RESPONSE REGULATOR receiver
AL504_06450	COG2201	protein-glutamate methylesterase activity
AL504_06455	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AL504_06460	COG0840	transmembrane signaling receptor activity
AL504_06465	COG0835	chemotaxis
AL504_06500	COG1191	sigma factor activity
AL504_06505	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL504_06505	COG4797	methyltransferase
AL504_06520	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AL504_06540	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AL504_06550	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL504_06580	COG0583	DNA-binding transcription factor activity
AL504_06590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL504_06595	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL504_06600	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AL504_06610	COG4566	intracellular signal transduction
AL504_06620	COG0339	signal peptide processing
AL504_06630	COG1999	signal sequence binding
AL504_06640	COG1538	Outer membrane efflux protein
AL504_06655	COG0583	DNA-binding transcription factor activity
AL504_06660	COG1187	pseudouridine synthase activity
AL504_06665	COG3161	chorismate lyase activity
AL504_06670	COG0477	Major facilitator Superfamily
AL504_06685	COG2130	NADP-dependent
AL504_06690	COG1309	transcriptional regulator
AL504_06695	COG4681	YaeQ
AL504_06700	COG4172	Belongs to the ABC transporter superfamily
AL504_06710	COG0601	transmembrane transport
AL504_06715	COG0747	negative chemotaxis
AL504_06725	COG0583	DNA-binding transcription factor activity
AL504_06755	COG2165	general secretion pathway protein
AL504_06825	COG0668	transmembrane transport
AL504_06830	COG0165	Argininosuccinate lyase
AL504_06850	COG0022	dehydrogenase e1 component
AL504_06860	COG4774	siderophore transport
AL504_06885	COG0789	Transcriptional regulator
AL504_06905	COG2271	Major facilitator Superfamily
AL504_06915	COG0307	riboflavin synthase, alpha
AL504_06925	COG2186	Transcriptional regulator
AL504_06930	COG1696	Membrane protein involved in D-alanine export
AL504_06940	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_06975	COG2070	2-Nitropropane dioxygenase
AL504_07025	COG0154	amidase activity
AL504_07030	COG2814	Major facilitator Superfamily
AL504_07040	COG2226	methyltransferase
AL504_07050	COG4608	Belongs to the ABC transporter superfamily
AL504_07055	COG0444	Belongs to the ABC transporter superfamily
AL504_07065	COG0601	transmembrane transport
AL504_07070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL504_07095	COG0747	negative chemotaxis
AL504_07130	COG0583	DNA-binding transcription factor activity
AL504_07145	COG1733	regulation of RNA biosynthetic process
AL504_07155	COG0583	DNA-binding transcription factor activity
AL504_07160	COG1132	(ABC) transporter
AL504_07205	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL504_07215	COG5265	(ABC) transporter
AL504_07220	COG1280	lysine exporter protein (LysE YggA)
AL504_07260	COG0318	PFAM AMP-dependent synthetase and ligase
AL504_07280	COG0477	Major facilitator Superfamily
AL504_07285	COG0235	Class ii aldolase
AL504_07315	COG2610	gluconate transmembrane transporter activity
AL504_07320	COG0583	DNA-binding transcription factor activity
AL504_07325	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_07330	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_07335	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
AL504_07380	COG1024	Enoyl-CoA hydratase
AL504_07385	COG5001	Diguanylate cyclase
AL504_07390	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_07395	COG0129	dihydroxy-acid dehydratase activity
AL504_07405	COG0583	DNA-binding transcription factor activity
AL504_07410	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL504_07415	COG3246	L-lysine catabolic process to acetate
AL504_07430	COG0243	molybdopterin cofactor binding
AL504_07435	COG3043	anaerobic respiration
AL504_07440	COG3005	denitrification pathway
AL504_07445	COG4133	protoheme IX ABC transporter activity
AL504_07460	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AL504_07495	COG3381	protein complex oligomerization
AL504_07510	COG4133	protoheme IX ABC transporter activity
AL504_07520	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL504_07530	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AL504_07540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL504_07545	COG3088	subunit of a heme lyase
AL504_07565	COG0109	protoheme IX farnesyltransferase activity
AL504_07570	COG0583	DNA-binding transcription factor activity
AL504_07585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL504_07595	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_07615	COG2207	Transcriptional regulator
AL504_07650	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_07665	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AL504_07670	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL504_07680	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_07685	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AL504_07690	COG0534	Mate efflux family protein
AL504_07705	COG0697	spore germination
AL504_07710	COG0697	spore germination
AL504_07725	COG1280	lysine exporter protein (LysE YggA)
AL504_07740	COG1280	lysine exporter protein (LysE YggA)
AL504_07745	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AL504_07750	COG3245	cytochrome
AL504_07760	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL504_07770	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AL504_07795	COG0318	PFAM AMP-dependent synthetase and ligase
AL504_07800	COG1960	acyl-CoA dehydrogenase activity
AL504_07815	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AL504_07825	COG2814	Major facilitator Superfamily
AL504_07840	COG0625	glutathione transferase activity
AL504_07850	COG0583	DNA-binding transcription factor activity
AL504_07860	COG0583	DNA-binding transcription factor activity
AL504_07880	COG0506	proline dehydrogenase activity
AL504_07885	COG0697	spore germination
AL504_07890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL504_07895	COG1959	2 iron, 2 sulfur cluster binding
AL504_07900	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL504_07900	COG1017	nitric oxide dioxygenase activity
AL504_07920	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL504_07925	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL504_07935	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AL504_07975	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL504_07985	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_07990	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL504_08000	COG1610	YqeY-like protein
AL504_08030	COG3706	GGDEF domain
AL504_08035	COG0457	Tetratricopeptide repeat
AL504_08040	COG0726	polysaccharide deacetylase
AL504_08040	COG1649	PFAM Uncharacterised BCR, COG1649
AL504_08045	COG1215	transferase activity, transferring glycosyl groups
AL504_08055	COG2223	nitrite transmembrane transporter activity
AL504_08060	COG4977	sequence-specific DNA binding
AL504_08060	COG1917	Cupin 2, conserved barrel domain protein
AL504_08070	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AL504_08085	COG0656	L-ascorbic acid biosynthetic process
AL504_08090	COG5265	(ABC) transporter
AL504_08120	COG1116	anion transmembrane transporter activity
AL504_08145	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_08150	COG0583	DNA-binding transcription factor activity
AL504_08180	COG1522	sequence-specific DNA binding
AL504_08205	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_08220	COG0456	acetyltransferase
AL504_08225	COG0384	phenazine biosynthesis protein PhzF
AL504_08250	COG0494	nUDIX hydrolase
AL504_08280	COG0776	regulation of translation
AL504_08285	COG0072	phenylalanine-tRNA ligase activity
AL504_08285	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL504_08290	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AL504_08295	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AL504_08300	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AL504_08310	COG2960	long-chain fatty acid transporting porin activity
AL504_08320	COG0347	Belongs to the P(II) protein family
AL504_08325	COG0004	ammonium transporteR
AL504_08330	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AL504_08335	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL504_08345	COG0189	ligase activity
AL504_08350	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AL504_08355	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AL504_08365	COG2197	response regulator
AL504_08370	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AL504_08375	COG0789	Transcriptional regulator
AL504_08405	COG1012	belongs to the aldehyde dehydrogenase family
AL504_08415	COG0601	transmembrane transport
AL504_08420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL504_08445	COG1609	Transcriptional regulator
AL504_08450	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AL504_08455	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL504_08460	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL504_08465	COG0129	dihydroxy-acid dehydratase activity
AL504_08470	COG2755	lipolytic protein G-D-S-L family
AL504_08470	COG0657	acetylesterase activity
AL504_08510	COG0135	phosphoribosylanthranilate isomerase activity
AL504_08515	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AL504_08520	COG0101	tRNA pseudouridine synthase activity
AL504_08535	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AL504_08540	COG0473	3-isopropylmalate dehydrogenase activity
AL504_08545	COG0066	3-isopropylmalate dehydratase activity
AL504_08550	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AL504_08555	COG4783	chaperone-mediated protein folding
AL504_08560	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AL504_08570	COG3706	GGDEF domain
AL504_08575	COG5002	protein histidine kinase activity
AL504_08585	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AL504_08595	COG1295	ribonuclease BN
AL504_08605	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AL504_08635	COG4964	Belongs to the GSP D family
AL504_08830	COG2369	cell adhesion
AL504_08840	COG5410	chromosome segregation
AL504_08940	COG5377	YqaJ viral recombinase family
AL504_08945	COG3723	Recombinational DNA repair protein, rece pathway
AL504_08955	COG1475	DNA binding
AL504_08970	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AL504_08970	COG2755	lipolytic protein G-D-S-L family
AL504_08985	COG0438	transferase activity, transferring glycosyl groups
AL504_09010	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AL504_09015	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AL504_09020	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AL504_09025	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AL504_09030	COG0330	HflC and HflK could
AL504_09035	COG0330	HflC and HflK could
AL504_09040	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AL504_09045	COG1923	regulation of RNA biosynthetic process
AL504_09050	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AL504_09055	COG1160	GTP binding
AL504_09060	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL504_09065	COG2976	Protein conserved in bacteria
AL504_09070	COG0124	histidyl-tRNA synthetase
AL504_09075	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AL504_09085	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AL504_09090	COG0105	UTP biosynthetic process
AL504_09095	COG0525	valine-tRNA ligase activity
AL504_09100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL504_09110	COG0765	amino acid transport
AL504_09115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_09120	COG1396	sequence-specific DNA binding
AL504_09125	COG0336	Belongs to the RNA methyltransferase TrmD family
AL504_09130	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AL504_09135	COG0228	four-way junction DNA binding
AL504_09145	COG0425	Belongs to the sulfur carrier protein TusA family
AL504_09150	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AL504_09165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL504_09175	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AL504_09180	COG2076	Multidrug Resistance protein
AL504_09185	COG0633	Ferredoxin
AL504_09185	COG3217	Mosc domain protein beta barrel domain protein
AL504_09190	COG5285	phytanoyl-CoA dioxygenase
AL504_09195	COG0662	Cupin 2, conserved barrel domain protein
AL504_09200	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL504_09220	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AL504_09225	COG2311	Membrane
AL504_09230	COG1309	transcriptional regulator
AL504_09245	COG0187	DNA topoisomerase II activity
AL504_09255	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AL504_09270	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AL504_09275	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AL504_09295	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AL504_09305	COG3391	amine dehydrogenase activity
AL504_09335	COG1846	Transcriptional regulator
AL504_09345	COG1566	PFAM secretion protein HlyD family protein
AL504_09350	COG2814	Major facilitator Superfamily
AL504_09360	COG0473	3-isopropylmalate dehydrogenase activity
AL504_09365	COG0433	COG0433 Predicted ATPase
AL504_09370	COG0217	transcriptional regulatory protein
AL504_09375	COG0151	Belongs to the GarS family
AL504_09380	COG0408	coproporphyrinogen oxidase activity
AL504_09385	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AL504_09390	COG0799	negative regulation of ribosome biogenesis
AL504_09395	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AL504_09400	COG0424	maF-like protein
AL504_09405	COG1301	dicarboxylic acid transport
AL504_09410	COG4191	Histidine kinase
AL504_09415	COG2204	response regulator
AL504_09445	COG1530	ribonuclease E activity
AL504_09515	COG1196	nuclear chromosome segregation
AL504_09700	COG3723	Recombinational DNA repair protein, rece pathway
AL504_09770	COG5001	Diguanylate cyclase
AL504_09770	COG4251	negative regulation of phosphorylation
AL504_09770	COG3706	GGDEF domain
AL504_09770	COG2203	Gaf domain
AL504_09785	COG0475	glutathione-regulated potassium exporter activity
AL504_09785	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AL504_09790	COG1132	(ABC) transporter
AL504_09815	COG0726	polysaccharide deacetylase
AL504_09830	COG0726	polysaccharide deacetylase
AL504_09835	COG0438	transferase activity, transferring glycosyl groups
AL504_09850	COG1116	anion transmembrane transporter activity
AL504_09855	COG0395	ABC-type sugar transport system, permease component
AL504_09860	COG1643	Atp-dependent helicase
AL504_09865	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AL504_09865	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AL504_09870	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AL504_09880	COG0704	Plays a role in the regulation of phosphate uptake
AL504_09890	COG1960	acyl-CoA dehydrogenase activity
AL504_09900	COG1322	Protein conserved in bacteria
AL504_09920	COG1177	transmembrane transport
AL504_09925	COG1176	ABC-type spermidine putrescine transport system, permease component I
AL504_09930	COG3842	ATPase activity
AL504_09940	COG3642	lipopolysaccharide core region biosynthetic process
AL504_09950	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AL504_09955	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL504_09975	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AL504_09980	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AL504_09985	COG2945	thiolester hydrolase activity
AL504_09985	COG0596	Alpha beta hydrolase
AL504_10005	COG3618	amidohydrolase
AL504_10010	COG0583	DNA-binding transcription factor activity
AL504_10015	COG5002	protein histidine kinase activity
AL504_10025	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL504_10035	COG1538	Outer membrane efflux protein
AL504_10040	COG0137	argininosuccinate synthase activity
AL504_10045	COG3158	transport of potassium into the cell
AL504_10050	COG0642	Histidine kinase
AL504_10055	COG0745	RESPONSE REGULATOR receiver
AL504_10080	COG0776	regulation of translation
AL504_10085	COG3128	pkhd-type hydroxylase
AL504_10095	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL504_10100	COG0557	exoribonuclease II activity
AL504_10120	COG2153	protein acetylation
AL504_10130	COG0679	Auxin Efflux Carrier
AL504_10135	COG2391	methyltransferase activity
AL504_10140	COG0069	glutamate synthase activity
AL504_10145	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL504_10155	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
AL504_10200	COG0697	spore germination
AL504_10320	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AL504_10360	COG3909	cytochrome
AL504_10370	COG0625	glutathione transferase activity
AL504_10375	COG0730	response to heat
AL504_10380	COG0482	sulfurtransferase activity
AL504_10385	COG0583	DNA-binding transcription factor activity
AL504_10400	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AL504_10405	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AL504_10410	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AL504_10415	COG0247	lactate metabolic process
AL504_10420	COG0277	FAD linked oxidase domain protein
AL504_10425	COG0277	FAD linked oxidase domain protein
AL504_10430	COG0277	FAD linked oxidase domain protein
AL504_10435	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL504_10440	COG0312	modulator of DNA gyrase
AL504_10455	COG0308	aminopeptidase N
AL504_10460	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AL504_10480	COG0436	Aminotransferase
AL504_10490	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AL504_10500	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AL504_10520	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL504_10530	COG0411	ABC transporter
AL504_10535	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_10550	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_10560	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AL504_10580	COG0181	hydroxymethylbilane synthase activity
AL504_10585	COG0861	Integral membrane protein TerC family
AL504_10590	COG0861	Integral membrane protein TerC family
AL504_10595	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AL504_10600	COG0045	succinate-CoA ligase (ADP-forming) activity
AL504_10610	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AL504_10615	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AL504_10620	COG0583	DNA-binding transcription factor activity
AL504_10625	COG2137	regulation of response to DNA damage stimulus
AL504_10630	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AL504_10640	COG0642	Histidine kinase
AL504_10665	COG0540	Belongs to the ATCase OTCase family
AL504_10725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL504_10760	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AL504_10770	COG0305	Participates in initiation and elongation during chromosome replication
AL504_10780	COG0359	binds to the 23S rRNA
AL504_10785	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AL504_10790	COG2965	DNA replication, synthesis of RNA primer
AL504_10795	COG0360	Binds together with S18 to 16S ribosomal RNA
AL504_10800	COG3739	integral membrane protein
AL504_10805	COG1469	GTP cyclohydrolase I activity
AL504_10810	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AL504_10815	COG0142	geranyltranstransferase activity
AL504_10820	COG1722	exodeoxyribonuclease VII activity
AL504_10830	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_10850	COG1840	ABC-type Fe3 transport system, periplasmic component
AL504_10855	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL504_10865	COG3842	ATPase activity
AL504_10870	COG0583	DNA-binding transcription factor activity
AL504_10890	COG0501	Belongs to the peptidase M48B family
AL504_10895	COG1760	l-serine dehydratase
AL504_10900	COG1283	sodium-dependent phosphate transmembrane transporter activity
AL504_10905	COG2801	Transposase and inactivated derivatives
AL504_10905	COG3415	Transposase
AL504_10915	COG0412	Dienelactone hydrolase
AL504_10930	COG1611	Belongs to the LOG family
AL504_10935	COG1473	amidohydrolase
AL504_10940	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_10965	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AL504_10970	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AL504_10975	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AL504_10980	COG2251	uridine kinase activity
AL504_10980	COG0195	Participates in both transcription termination and antitermination
AL504_10985	COG0779	Required for maturation of 30S ribosomal subunits
AL504_10990	COG1187	pseudouridine synthase activity
AL504_10995	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AL504_11005	COG0583	DNA-binding transcription factor activity
AL504_11010	COG0523	cobalamin synthesis protein
AL504_11015	COG0523	cobalamin synthesis protein
AL504_11030	COG0745	RESPONSE REGULATOR receiver
AL504_11040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL504_11045	COG0625	glutathione transferase activity
AL504_11060	COG2003	Belongs to the UPF0758 family
AL504_11065	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AL504_11070	COG3483	tryptophan 2,3-dioxygenase activity
AL504_11075	COG0254	rRNA binding
AL504_11085	COG0534	Mate efflux family protein
AL504_11095	COG2050	protein possibly involved in aromatic compounds catabolism
AL504_11100	COG1024	Enoyl-CoA hydratase
AL504_11105	COG1012	belongs to the aldehyde dehydrogenase family
AL504_11110	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL504_11115	COG2151	metal-sulfur cluster biosynthetic enzyme
AL504_11120	COG3396	Phenylacetate-CoA oxygenase
AL504_11125	COG3460	Phenylacetate-CoA oxygenase
AL504_11130	COG3396	Phenylacetate-CoA oxygenase
AL504_11135	COG3327	negative regulation of DNA-templated transcription, initiation
AL504_11140	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AL504_11145	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AL504_11150	COG0501	Belongs to the peptidase M48B family
AL504_11155	COG1162	GTPase activity
AL504_11165	COG0335	large ribosomal subunit rRNA binding
AL504_11195	COG0175	sulfate reduction
AL504_11205	COG4208	sulfate ABC transporter
AL504_11210	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AL504_11220	COG0450	alkyl hydroperoxide reductase
AL504_11225	COG1960	acyl-CoA dehydrogenase activity
AL504_11230	COG2985	domain, Protein
AL504_11255	COG0123	including yeast histone deacetylase and acetoin utilization protein
AL504_11260	COG2951	lytic endotransglycosylase activity
AL504_11290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL504_11295	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AL504_11300	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AL504_11320	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AL504_11325	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AL504_11345	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AL504_11360	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL504_11395	COG2951	lytic endotransglycosylase activity
AL504_11410	COG1132	(ABC) transporter
AL504_11415	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AL504_11415	COG0189	ligase activity
AL504_11420	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AL504_11420	COG0189	ligase activity
AL504_11425	COG3237	CsbD-like
AL504_11430	COG2823	Periplasmic or secreted lipoprotein
AL504_11450	COG2831	hemolysin activation secretion protein
AL504_11475	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
AL504_11480	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_11485	COG3243	poly(R)-hydroxyalkanoic acid synthase
AL504_11495	COG0564	pseudouridine synthase activity
AL504_11505	COG1199	ATP-dependent helicase activity
AL504_11510	COG2183	response to ionizing radiation
AL504_11520	COG0180	Tryptophanyl-tRNA synthetase
AL504_11545	COG4774	siderophore transport
AL504_11550	COG3712	iron ion homeostasis
AL504_11555	COG1595	DNA-templated transcription, initiation
AL504_11560	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AL504_11565	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL504_11570	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL504_11575	COG0567	Dehydrogenase, E1 component
AL504_11580	COG1522	sequence-specific DNA binding
AL504_11585	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AL504_11600	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL504_11605	COG1297	OPT oligopeptide transporter protein
AL504_11615	COG0280	phosphate acetyltransferase
AL504_11615	COG0281	malic enzyme
AL504_11630	COG0372	Belongs to the citrate synthase family
AL504_11635	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AL504_11640	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AL504_11645	COG1053	succinate dehydrogenase
AL504_11650	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AL504_11655	COG2009	succinate dehydrogenase
AL504_11660	COG2188	Transcriptional regulator
AL504_11665	COG0039	L-malate dehydrogenase activity
AL504_11720	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL504_11730	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AL504_11740	COG0148	phosphopyruvate hydratase activity
AL504_11750	COG0504	CTP synthase activity
AL504_11785	COG0747	negative chemotaxis
AL504_11790	COG4172	Belongs to the ABC transporter superfamily
AL504_11795	COG1446	asparaginase
AL504_11805	COG2153	protein acetylation
AL504_11830	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL504_11855	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AL504_11860	COG0697	spore germination
AL504_11875	COG3193	protein, possibly involved in utilization of glycolate and propanediol
AL504_11880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL504_11885	COG0791	NLP P60 protein
AL504_11895	COG0583	DNA-binding transcription factor activity
AL504_11920	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AL504_11950	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_11960	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AL504_11970	COG1381	Involved in DNA repair and RecF pathway recombination
AL504_11975	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AL504_11980	COG0571	ribonuclease III activity
AL504_11985	COG0681	Belongs to the peptidase S26 family
AL504_11990	COG0481	GTPase activity
AL504_11995	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL504_12020	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL504_12025	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL504_12035	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AL504_12040	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL504_12045	COG0416	fatty acid biosynthetic process
AL504_12050	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AL504_12060	COG0424	maF-like protein
AL504_12070	COG3023	N-Acetylmuramoyl-L-alanine amidase
AL504_12075	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AL504_12080	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AL504_12085	COG0546	phosphoglycolate phosphatase activity
AL504_12090	COG0564	pseudouridine synthase activity
AL504_12095	COG1530	ribonuclease E activity
AL504_12110	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AL504_12115	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AL504_12120	COG0159	tryptophan synthase activity
AL504_12125	COG0133	tryptophan synthase activity
AL504_12130	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL504_12140	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL504_12145	COG3228	Belongs to the MtfA family
AL504_12155	COG0251	oxidation-reduction process
AL504_12160	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AL504_12180	COG2878	Part of a membrane complex involved in electron transport
AL504_12185	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AL504_12190	COG0411	ABC transporter
AL504_12205	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL504_12220	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AL504_12240	COG0411	ABC transporter
AL504_12265	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AL504_12270	COG1122	ATPase activity
AL504_12275	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL504_12280	COG2917	probably involved in intracellular septation
AL504_12290	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL504_12295	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AL504_12305	COG1196	nuclear chromosome segregation
AL504_12310	COG0477	Major facilitator Superfamily
AL504_12315	COG1573	uracil-dna glycosylase
AL504_12320	COG1214	PFAM Peptidase M22, glycoprotease
AL504_12325	COG0745	RESPONSE REGULATOR receiver
AL504_12330	COG2205	protein histidine kinase activity
AL504_12335	COG0450	alkyl hydroperoxide reductase
AL504_12340	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL504_12350	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AL504_12355	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AL504_12360	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AL504_12365	COG0560	Phosphoserine phosphatase
AL504_12370	COG3210	domain, Protein
AL504_12380	COG4774	siderophore transport
AL504_12390	COG1007	ATP synthesis coupled electron transport
AL504_12405	COG0713	ATP synthesis coupled electron transport
AL504_12415	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL504_12420	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AL504_12425	COG1034	ATP synthesis coupled electron transport
AL504_12435	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AL504_12440	COG0649	NAD binding
AL504_12445	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL504_12450	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL504_12455	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL504_12460	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL504_12485	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AL504_12490	COG1597	lipid kinase activity
AL504_12510	COG1309	transcriptional regulator
AL504_12520	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL504_12540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL504_12545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL504_12550	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL504_12565	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL504_12605	COG0747	negative chemotaxis
AL504_12635	COG1522	sequence-specific DNA binding
AL504_12640	COG2354	Protein conserved in bacteria
AL504_12650	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
AL504_12655	COG3604	Transcriptional regulator
AL504_12670	COG1595	DNA-templated transcription, initiation
AL504_12695	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_12700	COG2851	Citrate transporter
AL504_12710	COG0642	Histidine kinase
AL504_12720	COG4566	intracellular signal transduction
AL504_12725	COG4191	Histidine kinase
AL504_12755	COG0659	secondary active sulfate transmembrane transporter activity
AL504_12765	COG3712	iron ion homeostasis
AL504_12770	COG1595	DNA-templated transcription, initiation
AL504_12800	COG1116	anion transmembrane transporter activity
AL504_12835	COG1910	domain protein
AL504_12845	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AL504_12885	COG0840	transmembrane signaling receptor activity
AL504_12910	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AL504_12915	COG0149	triose-phosphate isomerase activity
AL504_12920	COG3321	synthase
AL504_12920	COG0604	alcohol dehydrogenase
AL504_12940	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL504_12950	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL504_12970	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL504_12975	COG2819	hydrolase of the alpha beta superfamily
AL504_12990	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AL504_13000	COG1185	polyribonucleotide nucleotidyltransferase activity
AL504_13005	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AL504_13015	COG1183	phosphatidylcholine synthase activity
AL504_13020	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AL504_13025	COG0440	acetolactate synthase activity
AL504_13030	COG0028	Belongs to the TPP enzyme family
AL504_13035	COG1289	transmembrane transporter activity
AL504_13040	COG3022	response to hydroperoxide
AL504_13045	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_13065	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL504_13100	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AL504_13105	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AL504_13110	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL504_13125	COG0601	transmembrane transport
AL504_13145	COG0517	IMP dehydrogenase activity
AL504_13145	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AL504_13150	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AL504_13155	COG0251	oxidation-reduction process
AL504_13160	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AL504_13165	COG1674	ftsk spoiiie
AL504_13170	COG0492	ferredoxin-NADP+ reductase activity
AL504_13175	COG1193	negative regulation of DNA recombination
AL504_13185	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL504_13205	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AL504_13210	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AL504_13215	COG2205	protein histidine kinase activity
AL504_13220	COG0745	RESPONSE REGULATOR receiver
AL504_13235	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL504_13240	COG0840	transmembrane signaling receptor activity
AL504_13275	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AL504_13300	COG0612	Peptidase, M16
AL504_13310	COG0484	heat shock protein binding
AL504_13315	COG0443	Heat shock 70 kDa protein
AL504_13325	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AL504_13335	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AL504_13340	COG1420	regulation of RNA biosynthetic process
AL504_13345	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AL504_13350	COG0497	DNA recombination
AL504_13355	COG0735	belongs to the Fur family
AL504_13360	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL504_13365	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AL504_13370	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AL504_13440	COG0583	DNA-binding transcription factor activity
AL504_13450	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AL504_13455	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AL504_13460	COG0167	dihydroorotate dehydrogenase activity
AL504_13475	COG1414	Transcriptional regulator
AL504_13480	COG1058	Belongs to the CinA family
AL504_13480	COG1546	Belongs to the CinA family
AL504_13495	COG0513	Belongs to the DEAD box helicase family
AL504_13505	COG4771	TonB-dependent receptor
AL504_13510	COG2814	Major facilitator Superfamily
AL504_13550	COG4783	chaperone-mediated protein folding
AL504_13565	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL504_13570	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AL504_13585	COG0006	proline dipeptidase activity
AL504_13595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL504_13620	COG0632	four-way junction helicase activity
AL504_13625	COG1090	epimerase
AL504_13635	COG2255	four-way junction helicase activity
AL504_13640	COG3290	protein histidine kinase activity
AL504_13645	COG0745	RESPONSE REGULATOR receiver
AL504_13655	COG0514	ATP-dependent DNA helicase (RecQ)
AL504_13670	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL504_13680	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL504_13685	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL504_13690	COG1414	Transcriptional regulator
AL504_13700	COG2894	cell division
AL504_13705	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AL504_13720	COG0488	(ABC) transporter
AL504_13725	COG2746	aminoglycoside 3-N-acetyltransferase activity
AL504_13745	COG4608	Belongs to the ABC transporter superfamily
AL504_13750	COG0444	Belongs to the ABC transporter superfamily
AL504_13755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL504_13765	COG0747	negative chemotaxis
AL504_13790	COG4638	Rieske (2fe-2S)
AL504_13815	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AL504_13820	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_13835	COG0411	ABC transporter
AL504_13840	COG0410	ABC transporter
AL504_13845	COG0463	Glycosyl transferase, family 2
AL504_13845	COG1216	Glycosyl transferase, family 2
AL504_13865	COG0800	Aldolase
AL504_13875	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AL504_13890	COG1595	DNA-templated transcription, initiation
AL504_13895	COG3712	iron ion homeostasis
AL504_13925	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AL504_13930	COG1538	Outer membrane efflux protein
AL504_13935	COG1136	(ABC) transporter
AL504_13935	COG0577	efflux transmembrane transporter activity
AL504_13940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL504_13955	COG0259	pyridoxamine-phosphate oxidase activity
AL504_13960	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL504_13965	COG0579	oxidoreductase
AL504_13975	COG0583	DNA-binding transcription factor activity
AL504_14005	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL504_14010	COG0583	DNA-binding transcription factor activity
AL504_14015	COG1960	acyl-CoA dehydrogenase activity
AL504_14020	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_14025	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL504_14030	COG0531	amino acid
AL504_14035	COG0405	Gamma-glutamyltransferase
AL504_14045	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_14055	COG0114	fumarate hydratase activity
AL504_14060	COG0860	N-Acetylmuramoyl-L-alanine amidase
AL504_14070	COG0586	Pfam SNARE associated Golgi protein
AL504_14080	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AL504_14090	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AL504_14105	COG0617	tRNA 3'-terminal CCA addition
AL504_14115	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL504_14120	COG2301	Belongs to the HpcH HpaI aldolase family
AL504_14130	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
AL504_14140	COG1024	Enoyl-CoA hydratase
AL504_14150	COG1960	acyl-CoA dehydrogenase activity
AL504_14165	COG0318	PFAM AMP-dependent synthetase and ligase
AL504_14175	COG2070	2-Nitropropane dioxygenase
AL504_14190	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_14195	COG2030	dehydratase
AL504_14200	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL504_14215	COG1024	Enoyl-CoA hydratase
AL504_14225	COG0751	glycine-tRNA ligase activity
AL504_14230	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AL504_14235	COG0204	Acyl-transferase
AL504_14255	COG0242	peptide deformylase activity
AL504_14260	COG1960	acyl-CoA dehydrogenase activity
AL504_14265	COG0700	Nucleoside recognition
AL504_14270	COG0469	pyruvate kinase activity
AL504_14275	COG1929	Belongs to the glycerate kinase type-1 family
AL504_14280	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AL504_14285	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL504_14295	COG3178	'Phosphotransferase
AL504_14325	COG2154	pterin-4-alpha-carbinolamine dehydratase
AL504_14355	COG1595	DNA-templated transcription, initiation
AL504_14365	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_14380	COG2982	Protein involved in outer membrane biogenesis
AL504_14385	COG1368	sulfuric ester hydrolase activity
AL504_14390	COG2818	Glycosylase
AL504_14410	COG0735	belongs to the Fur family
AL504_14420	COG0583	DNA-binding transcription factor activity
AL504_14425	COG0840	transmembrane signaling receptor activity
AL504_14480	COG2011	ABC-type metal ion transport system permease component
AL504_14485	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AL504_14490	COG1501	Belongs to the glycosyl hydrolase 31 family
AL504_14495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL504_14495	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AL504_14500	COG0483	inositol monophosphate 1-phosphatase activity
AL504_14505	COG0318	PFAM AMP-dependent synthetase and ligase
AL504_14510	COG1473	amidohydrolase
AL504_14525	COG2855	membrane
AL504_14530	COG1607	acyl-coa hydrolase
AL504_14535	COG2239	Acts as a magnesium transporter
AL504_14550	COG1522	sequence-specific DNA binding
AL504_14555	COG0300	oxidoreductase activity
AL504_14565	COG0028	Belongs to the TPP enzyme family
AL504_14570	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_14585	COG0653	protein targeting
AL504_14590	COG0739	heme binding
AL504_14600	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AL504_14605	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AL504_14615	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AL504_14620	COG1181	Belongs to the D-alanine--D-alanine ligase family
AL504_14625	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AL504_14630	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AL504_14640	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AL504_14645	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL504_14650	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AL504_14660	COG3116	cell division
AL504_14665	COG0275	rRNA processing
AL504_14670	COG2001	Belongs to the MraZ family
AL504_14685	COG0418	dihydroorotase activity
AL504_14690	COG1473	amidohydrolase
AL504_14700	COG0583	DNA-binding transcription factor activity
AL504_14740	COG1522	sequence-specific DNA binding
AL504_14750	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL504_14755	COG4654	Cytochrome c, class I
AL504_14760	COG0129	dihydroxy-acid dehydratase activity
AL504_14805	COG2084	Dehydrogenase
AL504_14810	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AL504_14820	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL504_14855	COG0824	Thioesterase
AL504_14860	COG0811	peptide transport
AL504_14865	COG0848	biopolymer transport protein
AL504_14875	COG0823	Involved in the tonB-independent uptake of proteins
AL504_14890	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL504_14895	COG1120	ATPase activity
AL504_14910	COG1522	sequence-specific DNA binding
AL504_14920	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AL504_14935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL504_14940	COG0697	spore germination
AL504_14950	COG1346	cytolysis
AL504_14960	COG0583	DNA-binding transcription factor activity
AL504_14970	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL504_14990	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL504_15010	COG0583	DNA-binding transcription factor activity
AL504_15025	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AL504_15030	COG0463	Glycosyl transferase, family 2
AL504_15040	COG0786	glutamate:sodium symporter activity
AL504_15055	COG1671	Belongs to the UPF0178 family
AL504_15065	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AL504_15070	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL504_15080	COG0328	RNA-DNA hybrid ribonuclease activity
AL504_15085	COG2226	methyltransferase
AL504_15090	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL504_15095	COG0741	lytic transglycosylase activity
AL504_15095	COG1388	LysM domain
AL504_15135	COG1366	Belongs to the anti-sigma-factor antagonist family
AL504_15140	COG2172	sigma factor antagonist activity
AL504_15145	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AL504_15155	COG2770	Histidine kinase
AL504_15155	COG2208	phosphoserine phosphatase activity
AL504_15185	COG4792	protein secretion
AL504_15190	COG4791	protein targeting
AL504_15195	COG4794	Type iii secretion
AL504_15200	COG4790	Type iii secretion
AL504_15205	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AL504_15235	COG4669	(LipO)protein
AL504_15305	COG4789	Type iii secretion
AL504_15340	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_15350	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL504_15360	COG1942	4-Oxalocrotonate Tautomerase
AL504_15375	COG2719	SpoVR family
AL504_15380	COG2718	Belongs to the UPF0229 family
AL504_15385	COG2766	serine protein kinase
AL504_15400	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL504_15400	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL504_15405	COG1335	isochorismatase
AL504_15415	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AL504_15420	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AL504_15425	COG1280	lysine exporter protein (LysE YggA)
AL504_15435	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AL504_15445	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AL504_15450	COG0316	Belongs to the HesB IscA family
AL504_15460	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AL504_15465	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AL504_15470	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AL504_15490	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL504_15505	COG0312	modulator of DNA gyrase
AL504_15510	COG3028	Belongs to the UPF0307 family
AL504_15525	COG1116	anion transmembrane transporter activity
AL504_15530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL504_15535	COG1335	isochorismatase
AL504_15540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL504_15540	COG0045	succinate-CoA ligase (ADP-forming) activity
AL504_15540	COG1042	CoA-binding domain protein
AL504_15545	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL504_15550	COG2814	Major facilitator Superfamily
AL504_15560	COG0583	DNA-binding transcription factor activity
AL504_15570	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_15575	COG1522	sequence-specific DNA binding
AL504_15605	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AL504_15610	COG1696	Membrane protein involved in D-alanine export
AL504_15635	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AL504_15635	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AL504_15645	COG2264	protein methyltransferase activity
AL504_15650	COG0439	Biotin carboxylase
AL504_15655	COG0511	ligase activity, forming carbon-carbon bonds
AL504_15660	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AL504_15665	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL504_15670	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AL504_15675	COG3150	esterase
AL504_15680	COG0557	exoribonuclease II activity
AL504_15690	COG0642	Histidine kinase
AL504_15700	COG1175	transmembrane transport
AL504_15715	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AL504_15720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AL504_15730	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AL504_15740	COG1126	abc transporter atp-binding protein
AL504_15755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_15765	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AL504_15790	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AL504_15795	COG1678	Uncharacterized ACR, COG1678
AL504_15810	COG0352	thiamine-phosphate diphosphorylase activity
AL504_15815	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AL504_15820	COG0741	lytic transglycosylase activity
AL504_15830	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_15835	COG1335	isochorismatase
AL504_15840	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AL504_15845	COG4638	Rieske (2fe-2S)
AL504_15885	COG1024	Enoyl-CoA hydratase
AL504_15890	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_15905	COG3706	GGDEF domain
AL504_15925	COG0410	ABC transporter
AL504_15940	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL504_15960	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AL504_15980	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AL504_15985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL504_15995	COG1538	Outer membrane efflux protein
AL504_16015	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AL504_16020	COG0237	dephospho-CoA kinase activity
AL504_16040	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AL504_16045	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AL504_16055	COG0477	Major facilitator Superfamily
AL504_16060	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AL504_16090	COG1605	Chorismate mutase
AL504_16090	COG0077	Prephenate dehydratase
AL504_16100	COG2081	HI0933 family
AL504_16105	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL504_16130	COG1126	abc transporter atp-binding protein
AL504_16135	COG0765	amino acid transport
AL504_16140	COG4597	amino acid ABC transporter
AL504_16145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_16150	COG2884	Cell division ATP-binding protein ftsE
AL504_16155	COG2177	Part of the ABC transporter FtsEX involved in
AL504_16160	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AL504_16200	COG1194	a g-specific adenine glycosylase
AL504_16220	COG1021	2,3-dihydroxybenzoate-AMP ligase
AL504_16235	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_16250	COG0246	Mannitol dehydrogenase
AL504_16255	COG4948	Mandelate Racemase Muconate Lactonizing
AL504_16260	COG1126	abc transporter atp-binding protein
AL504_16265	COG0765	amino acid transport
AL504_16275	COG1063	alcohol dehydrogenase
AL504_16290	COG2186	Transcriptional regulator
AL504_16300	COG4771	TonB-dependent receptor
AL504_16305	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL504_16310	COG2022	thiamine diphosphate biosynthetic process
AL504_16315	COG0351	phosphomethylpyrimidine kinase
AL504_16320	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AL504_16330	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AL504_16340	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AL504_16355	COG2226	methyltransferase
AL504_16360	COG0745	RESPONSE REGULATOR receiver
AL504_16365	COG5002	protein histidine kinase activity
AL504_16385	COG2132	Multicopper oxidase
AL504_16400	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL504_16415	COG4774	siderophore transport
AL504_16440	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AL504_16445	COG1984	allophanate hydrolase subunit 2
AL504_16450	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AL504_16455	COG1802	Transcriptional regulator
AL504_16460	COG2860	membrane
AL504_16470	COG2223	nitrite transmembrane transporter activity
AL504_16475	COG2813	Specifically methylates the guanine in position
AL504_16475	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AL504_16480	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AL504_16485	COG2188	Transcriptional regulator
AL504_16490	COG2721	sulfolactate sulfo-lyase activity
AL504_16495	COG2721	sulfolactate sulfo-lyase activity
AL504_16500	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_16505	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL504_16510	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AL504_16540	COG2918	glutathione biosynthetic process
AL504_16550	COG2988	succinylglutamate desuccinylase activity
AL504_16560	COG0583	DNA-binding transcription factor activity
AL504_16570	COG1802	Transcriptional regulator
AL504_16585	COG1129	ABC transporter
AL504_16595	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL504_16605	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL504_16620	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL504_16645	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL504_16660	COG1309	transcriptional regulator
AL504_16670	COG1024	Enoyl-CoA hydratase
AL504_16675	COG1024	Enoyl-CoA hydratase
AL504_16680	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AL504_16690	COG0747	negative chemotaxis
AL504_16695	COG0583	DNA-binding transcription factor activity
AL504_16705	COG2988	succinylglutamate desuccinylase activity
AL504_16710	COG4166	transmembrane transport
AL504_16715	COG0601	transmembrane transport
AL504_16730	COG4608	Belongs to the ABC transporter superfamily
AL504_16740	COG2195	Cleaves the N-terminal amino acid of tripeptides
AL504_16745	COG2171	N-acyltransferase activity
AL504_16755	COG4221	oxidoreductase activity
AL504_16760	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AL504_16775	COG0210	DNA helicase
AL504_16780	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AL504_16785	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AL504_16795	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AL504_16800	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AL504_16805	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AL504_16810	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AL504_16815	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AL504_16820	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AL504_16830	COG0356	it plays a direct role in the translocation of protons across the membrane
AL504_16845	COG1024	Enoyl-CoA hydratase
AL504_16860	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AL504_16875	COG0583	DNA-binding transcription factor activity
AL504_16880	COG3473	Maleate cis-trans isomerase
AL504_16905	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL504_16910	COG1131	(ABC) transporter
AL504_16920	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL504_16925	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL504_16945	COG0583	DNA-binding transcription factor activity
AL504_16950	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AL504_16970	COG0037	tRNA processing
AL504_16980	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL504_16985	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL504_16995	COG2967	ApaG domain
AL504_17005	COG0546	phosphoglycolate phosphatase activity
AL504_17015	COG0512	Glutamine amidotransferase of anthranilate synthase
AL504_17020	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AL504_17025	COG0134	indole-3-glycerol-phosphate synthase activity
AL504_17030	COG3284	Transcriptional regulator
AL504_17035	COG1012	belongs to the aldehyde dehydrogenase family
AL504_17065	COG0709	Synthesizes selenophosphate from selenide and ATP
AL504_17070	COG1305	Transglutaminase-like
AL504_17075	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL504_17080	COG1442	glycosyl transferase family 8
AL504_17080	COG1216	Glycosyl transferase, family 2
AL504_17090	COG3276	selenocysteine insertion sequence binding
AL504_17095	COG1921	L-seryl-tRNASec selenium transferase activity
AL504_17105	COG2864	formate dehydrogenase
AL504_17110	COG0437	4 iron, 4 sulfur cluster binding
AL504_17115	COG0243	molybdopterin cofactor binding
AL504_17115	COG3383	formate dehydrogenase (NAD+) activity
AL504_17120	COG0243	molybdopterin cofactor binding
AL504_17120	COG3383	formate dehydrogenase (NAD+) activity
AL504_17130	COG1607	acyl-coa hydrolase
AL504_17165	COG3585	molybdate ion transport
AL504_17170	COG1116	anion transmembrane transporter activity
AL504_17175	COG1464	Belongs to the NlpA lipoprotein family
AL504_17180	COG2011	ABC-type metal ion transport system permease component
AL504_17195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL504_17200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL504_17205	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL504_17210	COG0431	NADPH-dependent FMN reductase
AL504_17215	COG1464	Belongs to the NlpA lipoprotein family
AL504_17240	COG0747	negative chemotaxis
AL504_17250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL504_17260	COG0589	response to stress
AL504_17275	COG1012	belongs to the aldehyde dehydrogenase family
AL504_17280	COG3069	C4-dicarboxylate transmembrane transporter activity
AL504_17290	COG1802	Transcriptional regulator
AL504_17350	COG3188	usher protein
AL504_17365	COG2814	Major facilitator Superfamily
AL504_17370	COG0840	transmembrane signaling receptor activity
AL504_17385	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AL504_17390	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AL504_17400	COG2188	Transcriptional regulator
AL504_17415	COG0737	Belongs to the 5'-nucleotidase family
AL504_17460	COG0463	Glycosyl transferase, family 2
AL504_17465	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AL504_17475	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL504_17485	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AL504_17490	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AL504_17495	COG5001	Diguanylate cyclase
AL504_17500	COG2423	ornithine cyclodeaminase activity
AL504_17505	COG0583	DNA-binding transcription factor activity
AL504_17510	COG2814	Major facilitator Superfamily
AL504_17520	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AL504_17540	COG1120	ATPase activity
AL504_17545	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL504_17550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL504_17555	COG4592	Periplasmic binding protein
AL504_17560	COG4774	siderophore transport
AL504_17565	COG2207	Transcriptional regulator
AL504_17580	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL504_17585	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AL504_17595	COG1595	DNA-templated transcription, initiation
AL504_17610	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AL504_17640	COG2814	Major facilitator Superfamily
AL504_17645	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AL504_17665	COG1999	signal sequence binding
AL504_17670	COG0109	protoheme IX farnesyltransferase activity
AL504_17675	COG1612	heme a metabolic process
AL504_17705	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AL504_17725	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AL504_17750	COG0069	glutamate synthase activity
AL504_17750	COG0067	glutamate synthase
AL504_17750	COG0070	glutamate synthase
AL504_17775	COG1984	allophanate hydrolase subunit 2
AL504_17790	COG0511	ligase activity, forming carbon-carbon bonds
AL504_17795	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AL504_17800	COG0583	DNA-binding transcription factor activity
AL504_17810	COG0583	DNA-binding transcription factor activity
AL504_17815	COG0477	Major facilitator Superfamily
AL504_17825	COG2070	2-Nitropropane dioxygenase
AL504_17830	COG1127	ABC transporter
AL504_17835	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AL504_17840	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AL504_17845	COG2853	Lipoprotein
AL504_17855	COG1131	(ABC) transporter
AL504_17860	COG0842	Transport permease protein
AL504_17870	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AL504_17875	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AL504_17880	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AL504_17885	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AL504_17890	COG0131	Imidazoleglycerol-phosphate dehydratase
AL504_17895	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AL504_17900	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AL504_17905	COG0107	imidazoleglycerol-phosphate synthase activity
AL504_17910	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AL504_17915	COG0140	phosphoribosyl-ATP diphosphatase activity
AL504_17920	COG0537	adenosine 5'-monophosphoramidase activity
AL504_17925	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AL504_17930	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AL504_17945	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL504_17950	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AL504_17955	COG1970	mechanosensitive ion channel activity
AL504_17960	COG0723	plastoquinol--plastocyanin reductase activity
AL504_17965	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AL504_17970	COG2857	Cytochrome c1
AL504_17975	COG0625	glutathione transferase activity
AL504_17980	COG2969	positive regulation of protein catabolic process
AL504_18040	COG5489	Protein of unknown function (DUF736)
AL504_18050	COG1396	sequence-specific DNA binding
AL504_18075	COG1192	Involved in chromosome partitioning
AL504_18090	COG4959	Type IV secretory pathway protease TraF
AL504_18110	COG1024	Enoyl-CoA hydratase
AL504_18115	COG0183	Belongs to the thiolase family
AL504_18120	COG0318	PFAM AMP-dependent synthetase and ligase
AL504_18145	COG2814	Major facilitator Superfamily
AL504_18150	COG1960	acyl-CoA dehydrogenase activity
AL504_18155	COG2030	dehydratase
AL504_18170	COG0583	DNA-binding transcription factor activity
AL504_18190	COG4962	Type ii secretion system protein e
AL504_18195	COG3838	Conjugal transfer protein Trbc
AL504_18205	COG3451	type IV secretory pathway VirB4
AL504_18215	COG3846	protein secretion by the type IV secretion system
AL504_18230	COG2948	multi-organism process
AL504_18265	COG0583	DNA-binding transcription factor activity
AL504_18275	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AL504_18285	COG3708	Transcriptional regulator
AL504_18285	COG2207	Transcriptional regulator
AL504_18295	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AL504_18300	COG0747	negative chemotaxis
AL504_18305	COG0601	transmembrane transport
AL504_18310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL504_18315	COG4172	Belongs to the ABC transporter superfamily
AL504_18320	COG1228	amidohydrolase
AL504_18325	COG5339	Protein conserved in bacteria
AL504_18330	COG5339	Protein conserved in bacteria
AL504_18335	COG0513	Belongs to the DEAD box helicase family
AL504_18340	COG1280	lysine exporter protein (LysE YggA)
AL504_18345	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AL504_18360	COG0697	spore germination
AL504_18365	COG0583	DNA-binding transcription factor activity
AL504_18380	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AL504_18395	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL504_18405	COG1609	Transcriptional regulator
AL504_18410	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AL504_18420	COG1653	transport
AL504_18425	COG1175	transmembrane transport
AL504_18430	COG0395	ABC-type sugar transport system, permease component
AL504_18465	COG0018	arginyl-trna synthetase
AL504_18475	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL504_18500	COG1280	lysine exporter protein (LysE YggA)
AL504_18515	COG1742	UPF0060 membrane protein
AL504_18530	COG1473	amidohydrolase
AL504_18535	COG1960	acyl-CoA dehydrogenase activity
AL504_18540	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AL504_18545	COG0183	Belongs to the thiolase family
AL504_18550	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AL504_18600	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_18615	COG0318	PFAM AMP-dependent synthetase and ligase
AL504_18620	COG1595	DNA-templated transcription, initiation
AL504_18640	COG2188	Transcriptional regulator
AL504_18650	COG1335	isochorismatase
AL504_18670	COG3339	Conserved Protein
AL504_18680	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
AL504_18705	COG4977	sequence-specific DNA binding
AL504_18725	COG1595	DNA-templated transcription, initiation
AL504_18730	COG3712	iron ion homeostasis
AL504_18740	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AL504_18745	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_18760	COG1309	transcriptional regulator
AL504_18765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_18770	COG0765	amino acid transport
AL504_18775	COG0765	amino acid transport
AL504_18805	COG2922	Belongs to the Smg family
AL504_18810	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL504_18830	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AL504_18835	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL504_18840	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_18845	COG0028	Belongs to the TPP enzyme family
AL504_18850	COG1522	sequence-specific DNA binding
AL504_18855	COG3781	membrane
AL504_18865	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AL504_18870	COG2814	Major facilitator Superfamily
AL504_18885	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL504_18900	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AL504_18910	COG1744	ABC transporter substrate-binding protein PnrA-like
AL504_18930	COG0402	S-adenosylhomocysteine deaminase activity
AL504_18940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL504_18945	COG0583	DNA-binding transcription factor activity
AL504_18950	COG0251	oxidation-reduction process
AL504_18975	COG1177	transmembrane transport
AL504_18980	COG1176	ABC-type spermidine putrescine transport system, permease component I
AL504_18985	COG3842	ATPase activity
AL504_18995	COG1609	Transcriptional regulator
AL504_19050	COG1177	transmembrane transport
AL504_19055	COG1176	ABC-type spermidine putrescine transport system, permease component I
AL504_19075	COG1304	FMN binding
AL504_19085	COG1254	Belongs to the acylphosphatase family
AL504_19100	COG1126	abc transporter atp-binding protein
AL504_19105	COG0765	amino acid transport
AL504_19110	COG0765	amino acid transport
AL504_19115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_19120	COG0583	DNA-binding transcription factor activity
AL504_19130	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AL504_19140	COG1741	Belongs to the pirin family
AL504_19155	COG0583	DNA-binding transcription factor activity
AL504_19165	COG0592	DNA-directed DNA polymerase activity
AL504_19170	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AL504_19175	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AL504_19180	COG0594	ribonuclease P activity
AL504_19190	COG0753	catalase activity
AL504_19195	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AL504_19205	COG3712	iron ion homeostasis
AL504_19220	COG1473	amidohydrolase
AL504_19225	COG4608	Belongs to the ABC transporter superfamily
AL504_19230	COG0444	Belongs to the ABC transporter superfamily
AL504_19235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL504_19240	COG0601	transmembrane transport
AL504_19250	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AL504_19260	COG0038	chloride channel
AL504_19270	COG2205	protein histidine kinase activity
AL504_19290	COG0436	Aminotransferase
AL504_19295	COG3180	Ammonia monooxygenase
AL504_19300	COG1278	Cold shock
AL504_19305	COG0445	tRNA wobble uridine modification
AL504_19310	COG0357	Ribosomal RNA small subunit methyltransferase G
AL504_19315	COG1192	Involved in chromosome partitioning
AL504_19325	COG1475	DNA binding
AL504_19330	COG0252	asparaginase activity
AL504_19335	COG0583	DNA-binding transcription factor activity
AL504_19360	COG1349	DNA-binding transcription factor activity
AL504_19370	COG3842	ATPase activity
AL504_19375	COG1840	ABC-type Fe3 transport system, periplasmic component
AL504_19415	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AL504_19425	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AL504_19435	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AL504_19440	COG0081	regulation of translation
AL504_19445	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AL504_19450	COG0222	ribosome binding
AL504_19455	COG0085	RNA polymerase activity
AL504_19460	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AL504_19475	COG5002	protein histidine kinase activity
AL504_19490	COG0745	RESPONSE REGULATOR receiver
AL504_19495	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AL504_19500	COG0049	tRNA binding
AL504_19505	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AL504_19510	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AL504_19515	COG0051	transcription antitermination factor activity, RNA binding
AL504_19520	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AL504_19525	COG0088	Forms part of the polypeptide exit tunnel
AL504_19530	COG0089	rRNA binding
AL504_19535	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AL504_19540	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AL504_19545	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AL504_19550	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AL504_19555	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AL504_19560	COG0255	Belongs to the universal ribosomal protein uL29 family
AL504_19565	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AL504_19580	COG3307	-O-antigen
AL504_19590	COG1215	transferase activity, transferring glycosyl groups
AL504_19605	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AL504_19645	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AL504_19665	COG0455	bacterial-type flagellum organization
AL504_19670	COG1215	transferase activity, transferring glycosyl groups
AL504_19675	COG1215	transferase activity, transferring glycosyl groups
AL504_19680	COG1215	transferase activity, transferring glycosyl groups
AL504_19685	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AL504_19690	COG0457	Tetratricopeptide repeat
AL504_19725	COG4177	L-phenylalanine transmembrane transporter activity
AL504_19730	COG0410	ABC transporter
AL504_19735	COG0411	ABC transporter
AL504_19750	COG2207	Transcriptional regulator
AL504_19770	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AL504_19775	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AL504_19780	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AL504_19785	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AL504_19790	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AL504_19795	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AL504_19800	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AL504_19805	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AL504_19810	COG1841	ribosomal large subunit assembly
AL504_19815	COG0200	Binds to the 23S rRNA
AL504_19820	COG0201	protein transport
AL504_19825	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AL504_19830	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AL504_19835	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AL504_19840	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AL504_19845	COG0202	RNA polymerase activity
AL504_19850	COG0203	ribosomal protein L17
AL504_19860	COG1324	tolerance protein
AL504_19865	COG4232	protein-disulfide reductase activity
AL504_19880	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AL504_19890	COG1333	cytochrome c biogenesis protein
AL504_19905	COG1965	Belongs to the frataxin family
AL504_19915	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AL504_19920	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AL504_19925	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AL504_19930	COG0625	glutathione transferase activity
AL504_19940	COG2814	Major facilitator Superfamily
AL504_19945	COG0629	single-stranded DNA binding
AL504_19950	COG2226	methyltransferase
AL504_19980	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AL504_19985	COG2186	Transcriptional regulator
AL504_20010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL504_20015	COG1956	GAF domain-containing protein
AL504_20020	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL504_20035	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL504_20060	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AL504_20065	COG3568	Endonuclease Exonuclease Phosphatase
AL504_20070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL504_20080	COG2814	Major facilitator Superfamily
AL504_20110	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL504_20145	COG1134	teichoic acid transport
AL504_20155	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_20160	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AL504_20170	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AL504_20180	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AL504_20190	COG2089	acid synthase
AL504_20195	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AL504_20200	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AL504_20205	COG1088	dTDP-glucose 4,6-dehydratase activity
AL504_20230	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AL504_20235	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AL504_20255	COG0673	inositol 2-dehydrogenase activity
AL504_20260	COG0859	PFAM glycosyl transferase family 9
AL504_20270	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AL504_20280	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AL504_20305	COG1686	Belongs to the peptidase S11 family
AL504_20315	COG2921	Belongs to the UPF0250 family
AL504_20320	COG0321	lipoyl(octanoyl) transferase activity
AL504_20335	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AL504_20340	COG2096	Adenosyltransferase
AL504_20350	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AL504_20355	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AL504_20360	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AL504_20365	COG0523	cobalamin synthesis protein
AL504_20370	COG0735	belongs to the Fur family
AL504_20385	COG0803	Belongs to the bacterial solute-binding protein 9 family
AL504_20395	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AL504_20400	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AL504_20410	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AL504_20415	COG1560	Kdo2-lipid A biosynthetic process
AL504_20425	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AL504_20430	COG0154	amidase activity
AL504_20435	COG0477	Major facilitator Superfamily
AL504_20445	COG0583	DNA-binding transcription factor activity
AL504_20450	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_20460	COG0066	3-isopropylmalate dehydratase activity
AL504_20475	COG0438	transferase activity, transferring glycosyl groups
AL504_20480	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AL504_20485	COG1950	PFAM Membrane protein of
AL504_20505	COG1305	Transglutaminase-like
AL504_20515	COG2308	Evidence 4 Homologs of previously reported genes of
AL504_20520	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AL504_20540	COG0513	Belongs to the DEAD box helicase family
AL504_20545	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AL504_20555	COG3210	domain, Protein
AL504_20555	COG3210	domain, Protein
AL504_20565	COG0351	phosphomethylpyrimidine kinase
AL504_20565	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AL504_20565	COG0352	thiamine-phosphate diphosphorylase activity
AL504_20580	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_20600	COG3189	MarR family transcriptional regulator
AL504_20605	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AL504_20630	COG0640	Transcriptional regulator
AL504_20690	COG1846	Transcriptional regulator
AL504_20695	COG1764	response to oxidative stress
AL504_20710	COG0411	ABC transporter
AL504_20725	COG0583	DNA-binding transcription factor activity
AL504_20740	COG0583	DNA-binding transcription factor activity
AL504_20750	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AL504_20755	COG0708	Exodeoxyribonuclease III
AL504_20760	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AL504_20770	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AL504_20775	COG0154	amidase activity
AL504_20780	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AL504_20785	COG1077	Cell shape determining protein MreB Mrl
AL504_20790	COG1792	Involved in formation and maintenance of cell shape
AL504_20800	COG0768	penicillin binding
AL504_20805	COG0772	Belongs to the SEDS family
AL504_20815	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AL504_20820	COG0471	metal ion transport
AL504_20825	COG1309	transcriptional regulator
AL504_20835	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AL504_20845	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL504_20855	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AL504_20860	COG0792	nuclease activity
AL504_20870	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AL504_20880	COG1660	Displays ATPase and GTPase activities
AL504_20895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL504_20900	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AL504_20910	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AL504_20915	COG1137	ATPase activity
AL504_20940	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AL504_20955	COG1294	oxidase, subunit
AL504_20960	COG4988	ABC transporter
AL504_20965	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AL504_20970	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AL504_20985	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL504_20990	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AL504_20995	COG1238	metal cluster binding
AL504_21010	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_21015	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AL504_21020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL504_21025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_21040	COG0758	DNA mediated transformation
AL504_21045	COG0242	peptide deformylase activity
AL504_21050	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AL504_21060	COG0546	phosphoglycolate phosphatase activity
AL504_21080	COG1733	regulation of RNA biosynthetic process
AL504_21085	COG2076	Multidrug Resistance protein
AL504_21095	COG1280	lysine exporter protein (LysE YggA)
AL504_21100	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AL504_21100	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AL504_21110	COG5000	phosphorelay sensor kinase activity
AL504_21115	COG2204	response regulator
AL504_21120	COG0569	domain protein
AL504_21125	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AL504_21130	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AL504_21135	COG2226	methyltransferase
AL504_21150	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_21155	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AL504_21160	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AL504_21165	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AL504_21175	COG0588	phosphoglycerate mutase activity
AL504_21180	COG4942	peptidase
AL504_21185	COG0793	Belongs to the peptidase S41A family
AL504_21190	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AL504_21195	COG5001	Diguanylate cyclase
AL504_21195	COG3300	MHYT domain
AL504_21200	COG2186	Transcriptional regulator
AL504_21210	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AL504_21215	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL504_21215	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL504_21230	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AL504_21235	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AL504_21240	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AL504_21245	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AL504_21250	COG0142	geranyltranstransferase activity
AL504_21275	COG2986	histidine ammonia-lyase
AL504_21280	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL504_21340	COG0235	Class ii aldolase
AL504_21345	COG3622	Belongs to the hyi family
AL504_21350	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL504_21355	COG2084	Dehydrogenase
AL504_21360	COG3395	kinase activity
AL504_21365	COG2186	Transcriptional regulator
AL504_21375	COG0477	Major facilitator Superfamily
AL504_21390	COG3622	Belongs to the hyi family
AL504_21410	COG1522	sequence-specific DNA binding
AL504_21415	COG1280	lysine exporter protein (LysE YggA)
AL504_21425	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AL504_21430	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AL504_21435	COG2890	protein-(glutamine-N5) methyltransferase activity
AL504_21440	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AL504_21455	COG1464	Belongs to the NlpA lipoprotein family
AL504_21475	COG0318	PFAM AMP-dependent synthetase and ligase
AL504_21500	COG0477	Major facilitator Superfamily
AL504_21505	COG0583	DNA-binding transcription factor activity
AL504_21515	COG0583	DNA-binding transcription factor activity
AL504_21530	COG0625	glutathione transferase activity
AL504_21545	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_21565	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL504_21575	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_21580	COG1802	Transcriptional regulator
AL504_21585	COG0288	reversible hydration of carbon dioxide
AL504_21605	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AL504_21620	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AL504_21630	COG1414	Transcriptional regulator
AL504_21635	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_21640	COG2031	fatty acid transporter
AL504_21645	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL504_21650	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AL504_21655	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AL504_21675	COG0583	DNA-binding transcription factor activity
AL504_21680	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL504_21695	COG0129	dihydroxy-acid dehydratase activity
AL504_21700	COG0583	DNA-binding transcription factor activity
AL504_21705	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL504_21710	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL504_21720	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AL504_21725	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_21730	COG0410	ABC transporter
AL504_21735	COG0411	ABC transporter
AL504_21745	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL504_21755	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AL504_21765	COG2186	Transcriptional regulator
AL504_21775	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
AL504_21795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL504_21800	COG0583	DNA-binding transcription factor activity
AL504_21805	COG0628	permease
AL504_21815	COG0477	Major facilitator Superfamily
AL504_21830	COG1695	Transcriptional regulator
AL504_21840	COG0583	DNA-binding transcription factor activity
AL504_21985	COG0583	DNA-binding transcription factor activity
AL504_21990	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_22000	COG3246	L-lysine catabolic process to acetate
AL504_22005	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AL504_22010	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL504_22030	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL504_22035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_22060	COG2233	PERMEase
AL504_22070	COG0326	Molecular chaperone. Has ATPase activity
AL504_22075	COG1396	sequence-specific DNA binding
AL504_22080	COG3550	peptidyl-serine autophosphorylation
AL504_22085	COG2814	Major facilitator Superfamily
AL504_22090	COG4774	siderophore transport
AL504_22105	COG1131	(ABC) transporter
AL504_22110	COG2271	Major facilitator Superfamily
AL504_22115	COG4948	Mandelate Racemase Muconate Lactonizing
AL504_22120	COG0800	Aldolase
AL504_22130	COG1414	Transcriptional regulator
AL504_22150	COG3550	peptidyl-serine autophosphorylation
AL504_22180	COG0583	DNA-binding transcription factor activity
AL504_22185	COG1012	belongs to the aldehyde dehydrogenase family
AL504_22205	COG0625	glutathione transferase activity
AL504_22220	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL504_22225	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AL504_22230	COG1652	LysM domain
AL504_22255	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AL504_22260	COG0583	DNA-binding transcription factor activity
AL504_22265	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL504_22270	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL504_22300	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AL504_22320	COG3246	L-lysine catabolic process to acetate
AL504_22325	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_22335	COG0477	Major facilitator Superfamily
AL504_22365	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL504_22380	COG2205	protein histidine kinase activity
AL504_22400	COG0165	Argininosuccinate lyase
AL504_22410	COG2828	Protein conserved in bacteria
AL504_22425	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AL504_22435	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AL504_22475	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AL504_22490	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AL504_22495	COG0477	Major facilitator Superfamily
AL504_22500	COG1234	tRNA 3'-trailer cleavage
AL504_22510	COG0625	glutathione transferase activity
AL504_22520	COG3258	Cytochrome c
AL504_22555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL504_22560	COG1294	oxidase, subunit
AL504_22565	COG1271	oxidase subunit
AL504_22570	COG1942	4-Oxalocrotonate Tautomerase
AL504_22575	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_22585	COG0697	spore germination
AL504_22595	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_22605	COG0842	Transport permease protein
AL504_22610	COG1129	ABC transporter
AL504_22610	COG0842	Transport permease protein
AL504_22615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL504_22625	COG3243	poly(R)-hydroxyalkanoic acid synthase
AL504_22635	COG4774	siderophore transport
AL504_22645	COG1595	DNA-templated transcription, initiation
AL504_22650	COG2200	EAL domain
AL504_22675	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AL504_22680	COG0745	RESPONSE REGULATOR receiver
AL504_22690	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AL504_22690	COG2755	lipolytic protein G-D-S-L family
AL504_22710	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL504_22710	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL504_22720	COG0489	protein tyrosine kinase activity
AL504_22735	COG0717	Belongs to the dCTP deaminase family
AL504_22745	COG3706	GGDEF domain
AL504_22760	COG1982	Orn Lys Arg decarboxylase major
AL504_22765	COG2081	HI0933 family
AL504_22780	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AL504_22785	COG0509	glycine decarboxylation via glycine cleavage system
AL504_22790	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AL504_22790	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AL504_22805	COG0154	amidase activity
AL504_22810	COG4172	Belongs to the ABC transporter superfamily
AL504_22815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL504_22820	COG0601	transmembrane transport
AL504_22825	COG0747	negative chemotaxis
AL504_22845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL504_22860	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AL504_22870	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
AL504_22875	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL504_22880	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AL504_22895	COG0438	transferase activity, transferring glycosyl groups
AL504_22905	COG0438	transferase activity, transferring glycosyl groups
AL504_22910	COG0438	transferase activity, transferring glycosyl groups
AL504_22915	COG0438	transferase activity, transferring glycosyl groups
AL504_22920	COG0405	Gamma-glutamyltransferase
AL504_22925	COG0166	Belongs to the GPI family
AL504_22940	COG0277	FAD linked oxidase domain protein
AL504_22945	COG0745	RESPONSE REGULATOR receiver
AL504_22950	COG2205	protein histidine kinase activity
AL504_22960	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL504_22970	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL504_22975	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL504_22980	COG2186	Transcriptional regulator
AL504_22985	COG1368	sulfuric ester hydrolase activity
AL504_22990	COG0204	Acyl-transferase
AL504_23000	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AL504_23025	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AL504_23035	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AL504_23040	COG0840	transmembrane signaling receptor activity
AL504_23045	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AL504_23055	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AL504_23060	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AL504_23065	COG0193	aminoacyl-tRNA hydrolase activity
AL504_23075	COG0012	GTP binding
AL504_23080	COG4804	nuclease activity
AL504_23105	COG2814	Major facilitator Superfamily
AL504_23120	COG3135	benzoate transporter
AL504_23125	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL504_23130	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AL504_23135	COG0742	ribosomal rna small subunit methyltransferase
AL504_23160	COG3639	organic phosphonate transmembrane transporter activity
AL504_23165	COG3639	organic phosphonate transmembrane transporter activity
AL504_23170	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AL504_23195	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AL504_23200	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AL504_23215	COG1058	Belongs to the CinA family
AL504_23215	COG1546	Belongs to the CinA family
AL504_23220	COG0284	orotidine-5'-phosphate decarboxylase activity
AL504_23225	COG1252	NADH dehydrogenase
AL504_23230	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AL504_23235	COG0246	Mannitol dehydrogenase
AL504_23240	COG0410	ABC transporter
AL504_23245	COG1137	ATPase activity
AL504_23270	COG1917	Cupin 2, conserved barrel domain protein
AL504_23290	COG4774	siderophore transport
AL504_23305	COG1846	Transcriptional regulator
AL504_23315	COG0459	protein refolding
AL504_23320	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AL504_23355	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL504_23380	COG0372	Belongs to the citrate synthase family
AL504_23395	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_23400	COG2207	Transcriptional regulator
AL504_23410	COG0583	DNA-binding transcription factor activity
AL504_23425	COG0243	molybdopterin cofactor binding
AL504_23430	COG0038	chloride channel
AL504_23435	COG4191	Histidine kinase
AL504_23460	COG2200	EAL domain
AL504_23465	COG0300	oxidoreductase activity
AL504_23490	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL504_23495	COG4605	iron ion homeostasis
AL504_23500	COG4604	ABC transporter, ATP-binding protein
AL504_23505	COG4607	ABC-type enterochelin transport system periplasmic component
AL504_23510	COG4774	siderophore transport
AL504_23535	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL504_23580	COG0384	phenazine biosynthesis protein PhzF
AL504_23605	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AL504_23615	COG0745	RESPONSE REGULATOR receiver
AL504_23645	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL504_23660	COG0277	FAD linked oxidase domain protein
AL504_23675	COG0793	Belongs to the peptidase S41A family
AL504_23690	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_23695	COG2267	carboxylic ester hydrolase activity
AL504_23705	COG0583	DNA-binding transcription factor activity
AL504_23720	COG0154	amidase activity
AL504_23730	COG1595	DNA-templated transcription, initiation
AL504_23745	COG4772	TonB-dependent receptor
AL504_23750	COG3712	iron ion homeostasis
AL504_23755	COG1595	DNA-templated transcription, initiation
AL504_23775	COG0583	DNA-binding transcription factor activity
AL504_23780	COG0583	DNA-binding transcription factor activity
AL504_23795	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_23805	COG0697	spore germination
AL504_23810	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL504_23820	COG1960	acyl-CoA dehydrogenase activity
AL504_23825	COG0583	DNA-binding transcription factor activity
AL504_23830	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_23835	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL504_23855	COG2814	Major facilitator Superfamily
AL504_23890	COG0431	NADPH-dependent FMN reductase
AL504_23895	COG0798	PFAM Bile acid sodium symporter
AL504_23930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL504_23985	COG4172	Belongs to the ABC transporter superfamily
AL504_23990	COG1793	dna ligase
AL504_23990	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AL504_23995	COG1793	dna ligase
AL504_24000	COG1201	RNA secondary structure unwinding
AL504_24010	COG1132	(ABC) transporter
AL504_24025	COG4771	TonB-dependent receptor
AL504_24065	COG3712	iron ion homeostasis
AL504_24075	COG0028	Belongs to the TPP enzyme family
AL504_24130	COG0583	DNA-binding transcription factor activity
AL504_24135	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL504_24145	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL504_24160	COG0596	Alpha beta hydrolase
AL504_24170	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL504_24195	COG0740	serine-type endopeptidase activity
AL504_24205	COG0640	Transcriptional regulator
AL504_24210	COG2203	Gaf domain
AL504_24210	COG2199	diguanylate cyclase activity
AL504_24215	COG0840	transmembrane signaling receptor activity
AL504_24240	COG4948	Mandelate Racemase Muconate Lactonizing
AL504_24245	COG0583	DNA-binding transcription factor activity
AL504_24250	COG0456	acetyltransferase
AL504_24260	COG0023	Translation Initiation Factor
AL504_24265	COG0583	DNA-binding transcription factor activity
AL504_24270	COG0656	L-ascorbic acid biosynthetic process
AL504_24280	COG0667	Aldo Keto reductase
AL504_24290	COG0243	molybdopterin cofactor binding
AL504_24295	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL504_24295	COG2146	nitrite reductase [NAD(P)H] activity
AL504_24300	COG2146	nitrite reductase [NAD(P)H] activity
AL504_24300	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL504_24305	COG3707	response regulator
AL504_24330	COG2197	response regulator
AL504_24355	COG0625	glutathione transferase activity
AL504_24370	COG2814	Major facilitator Superfamily
AL504_24380	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL504_24385	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL504_24395	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AL504_24400	COG1845	cytochrome c oxidase, subunit III
AL504_24405	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AL504_24410	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AL504_24415	COG0477	Major facilitator Superfamily
AL504_24425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_24430	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL504_24470	COG0583	DNA-binding transcription factor activity
AL504_24485	COG4106	trans-aconitate 2-methyltransferase activity
AL504_24490	COG2207	Transcriptional regulator
AL504_24495	COG2807	transmembrane transport
AL504_24520	COG0330	HflC and HflK could
AL504_24525	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL504_24540	COG3712	iron ion homeostasis
AL504_24550	COG4221	oxidoreductase activity
AL504_24565	COG3712	iron ion homeostasis
AL504_24575	COG1595	DNA-templated transcription, initiation
AL504_24580	COG3712	iron ion homeostasis
AL504_24595	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AL504_24610	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL504_24615	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_24620	COG1285	pathogenesis
AL504_24625	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AL504_24640	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AL504_24665	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL504_24670	COG1396	sequence-specific DNA binding
AL504_24690	COG0583	DNA-binding transcription factor activity
AL504_24695	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_24725	COG0697	spore germination
AL504_24730	COG2207	Transcriptional regulator
AL504_24730	COG1917	Cupin 2, conserved barrel domain protein
AL504_24740	COG0281	malic enzyme
AL504_24740	COG0280	phosphate acetyltransferase
AL504_24760	COG4772	TonB-dependent receptor
AL504_24775	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AL504_24780	COG1845	cytochrome c oxidase, subunit III
AL504_24785	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AL504_24795	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AL504_24815	COG1999	signal sequence binding
AL504_24835	COG1388	LysM domain
AL504_24835	COG4942	peptidase
AL504_24845	COG0765	amino acid transport
AL504_24850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_24855	COG3191	aminopeptidase activity
AL504_24860	COG1272	protein, Hemolysin III
AL504_24865	COG1522	sequence-specific DNA binding
AL504_24875	COG1113	amino acid transport
AL504_24880	COG0583	DNA-binding transcription factor activity
AL504_24905	COG2378	regulation of single-species biofilm formation
AL504_24935	COG1595	DNA-templated transcription, initiation
AL504_24940	COG3712	iron ion homeostasis
AL504_24950	COG3720	iron ion transport
AL504_24955	COG4558	Periplasmic binding protein
AL504_24960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL504_24965	COG1120	ATPase activity
AL504_24970	COG1666	GTP binding
AL504_24980	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AL504_24985	COG0671	phosphoesterase, PA-phosphatase related
AL504_24995	COG4585	Histidine kinase
AL504_25015	COG4774	siderophore transport
AL504_25025	COG0410	ABC transporter
AL504_25030	COG0411	ABC transporter
AL504_25040	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL504_25080	COG0456	acetyltransferase
AL504_25085	COG0583	DNA-binding transcription factor activity
AL504_25090	COG2828	Protein conserved in bacteria
AL504_25110	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_25125	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL504_25140	COG0745	RESPONSE REGULATOR receiver
AL504_25145	COG2205	protein histidine kinase activity
AL504_25160	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AL504_25165	COG0583	DNA-binding transcription factor activity
AL504_25200	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AL504_25205	COG3383	formate dehydrogenase (NAD+) activity
AL504_25225	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AL504_25230	COG0746	molybdenum cofactor guanylyltransferase activity
AL504_25235	COG0303	'Molybdopterin
AL504_25240	COG0521	Mo-molybdopterin cofactor biosynthetic process
AL504_25245	COG0314	molybdopterin synthase activity
AL504_25255	COG0315	cyclic pyranopterin monophosphate synthase activity
AL504_25265	COG0412	Dienelactone hydrolase
AL504_25275	COG0678	peroxiredoxin activity
AL504_25285	COG0697	spore germination
AL504_25290	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AL504_25295	COG2197	response regulator
AL504_25330	COG0667	Aldo Keto reductase
AL504_25335	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AL504_25340	COG4535	Mg2 and Co2 transporter CorC
AL504_25345	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AL504_25350	COG1702	phosphate starvation-inducible protein PhoH
AL504_25355	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AL504_25365	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AL504_25385	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL504_25390	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL504_25395	COG1862	Preprotein translocase
AL504_25400	COG3077	Addiction module antitoxin, RelB DinJ family
AL504_25410	COG0343	queuine tRNA-ribosyltransferase activity
AL504_25415	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AL504_25425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL504_25440	COG2027	D-alanyl-D-alanine carboxypeptidase
AL504_25445	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AL504_25450	COG1648	precorrin-2 dehydrogenase activity
AL504_25450	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AL504_25455	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL504_25465	COG1116	anion transmembrane transporter activity
AL504_25475	COG4575	ribosome binding
AL504_25490	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AL504_25495	COG0741	lytic transglycosylase activity
AL504_25505	COG0436	Aminotransferase
AL504_25515	COG0281	malic enzyme
AL504_25515	COG0280	phosphate acetyltransferase
AL504_25525	COG2732	(Barnase) inhibitor
AL504_25530	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AL504_25540	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AL504_25545	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AL504_25550	COG0126	phosphoglycerate kinase activity
AL504_25565	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AL504_25570	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AL504_25590	COG0625	glutathione transferase activity
AL504_25610	COG0789	Transcriptional regulator
AL504_25625	COG0306	phosphate transporter
AL504_25635	COG0521	Mo-molybdopterin cofactor biosynthetic process
AL504_25645	COG0739	heme binding
AL504_25655	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AL504_25665	COG0640	Transcriptional regulator
AL504_25675	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AL504_25680	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AL504_25685	COG3639	organic phosphonate transmembrane transporter activity
AL504_25700	COG0405	Gamma-glutamyltransferase
AL504_25705	COG0583	DNA-binding transcription factor activity
AL504_25710	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AL504_25715	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AL504_25720	COG3454	Phosphonate metabolism
AL504_25725	COG2188	Transcriptional regulator
AL504_25730	COG3624	Phosphonate C-P lyase system protein PhnG
AL504_25735	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AL504_25740	COG3626	phosphonate metabolism
AL504_25745	COG3627	carbon phosphorus lyase activity
AL504_25750	COG4107	phosphonate C-P lyase system protein PhnK
AL504_25755	COG4778	phosphonate C-P lyase system protein PhnL
AL504_25760	COG3454	Phosphonate metabolism
AL504_25775	COG1301	dicarboxylic acid transport
AL504_25795	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AL504_25800	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AL504_25805	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AL504_25810	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AL504_25815	COG0009	L-threonylcarbamoyladenylate synthase
AL504_25820	COG1414	Transcriptional regulator
AL504_25825	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AL504_25840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_25845	COG1414	Transcriptional regulator
AL504_25850	COG0010	Belongs to the arginase family
AL504_25860	COG0765	amino acid transport
AL504_25865	COG1126	abc transporter atp-binding protein
AL504_25870	COG0028	Belongs to the TPP enzyme family
AL504_25880	COG0411	ABC transporter
AL504_25885	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL504_25915	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AL504_25935	COG2030	dehydratase
AL504_25960	COG0028	Belongs to the TPP enzyme family
AL504_25965	COG0583	DNA-binding transcription factor activity
AL504_25970	COG4974	Belongs to the 'phage' integrase family
AL504_25975	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AL504_26010	COG0318	PFAM AMP-dependent synthetase and ligase
AL504_26015	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL504_26025	COG1024	Enoyl-CoA hydratase
AL504_26030	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL504_26045	COG2070	2-Nitropropane dioxygenase
AL504_26060	COG1074	ATP-dependent DNA helicase activity
AL504_26085	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AL504_26095	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AL504_26100	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL504_26105	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL504_26115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL504_26130	COG0745	RESPONSE REGULATOR receiver
AL504_26145	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AL504_26150	COG0505	Belongs to the CarA family
AL504_26155	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AL504_26165	COG4221	oxidoreductase activity
AL504_26170	COG0406	alpha-ribazole phosphatase activity
AL504_26190	COG1840	ABC-type Fe3 transport system, periplasmic component
AL504_26200	COG2233	PERMEase
AL504_26205	COG0840	transmembrane signaling receptor activity
AL504_26210	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL504_26215	COG1534	Rna-binding protein
AL504_26220	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AL504_26225	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AL504_26235	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AL504_26270	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AL504_26275	COG2814	Major facilitator Superfamily
AL504_26285	COG0477	Major facilitator Superfamily
AL504_26290	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL504_26305	COG2841	Protein conserved in bacteria
AL504_26320	COG1595	DNA-templated transcription, initiation
AL504_26330	COG0583	DNA-binding transcription factor activity
AL504_26335	COG2207	Transcriptional regulator
AL504_26340	COG0667	Aldo Keto reductase
AL504_26365	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AL504_26370	COG0500	methyltransferase
AL504_26400	COG0517	IMP dehydrogenase activity
AL504_26410	COG3938	Belongs to the proline racemase family
AL504_26415	COG1177	transmembrane transport
AL504_26420	COG1176	ABC-type spermidine putrescine transport system, permease component I
AL504_26425	COG3842	ATPase activity
AL504_26485	COG1511	domain protein
AL504_26485	COG3264	Mechanosensitive ion channel
AL504_26490	COG0583	DNA-binding transcription factor activity
AL504_26495	COG0427	acetyl-CoA hydrolase
AL504_26500	COG0583	DNA-binding transcription factor activity
AL504_26540	COG0235	Class ii aldolase
AL504_26550	COG0583	DNA-binding transcription factor activity
AL504_26565	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL504_26575	COG0477	Major facilitator Superfamily
AL504_26585	COG0154	amidase activity
AL504_26605	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AL504_26620	COG0495	leucyl-tRNA aminoacylation
AL504_26625	COG2814	Major facilitator Superfamily
AL504_26630	COG1846	Transcriptional regulator
AL504_26640	COG1686	Belongs to the peptidase S11 family
AL504_26675	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AL504_26680	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AL504_26685	COG2814	Major facilitator Superfamily
AL504_26690	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL504_26700	COG4176	ABC-type proline glycine betaine transport system permease component
AL504_26720	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL504_26725	COG2706	6-phosphogluconolactonase activity
AL504_26730	COG4214	carbohydrate transport
AL504_26735	COG1129	ABC transporter
AL504_26740	COG4213	ABC transporter substrate-binding protein
AL504_26750	COG0183	Belongs to the thiolase family
AL504_26760	COG1802	Transcriptional regulator
AL504_26770	COG1024	Enoyl-CoA hydratase
AL504_26775	COG0318	PFAM AMP-dependent synthetase and ligase
AL504_26785	COG0667	Aldo Keto reductase
AL504_26795	COG4120	Belongs to the binding-protein-dependent transport system permease family
AL504_26810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL504_26820	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AL504_26840	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AL504_26845	COG0725	ABC transporter, periplasmic molybdate-binding protein
AL504_26850	COG4149	molybdate abc transporter
AL504_26855	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AL504_26880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL504_26885	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL504_26890	COG1538	Outer membrane efflux protein
AL504_26895	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AL504_26900	COG0736	holo-[acyl-carrier-protein] synthase activity
AL504_26905	COG1472	Belongs to the glycosyl hydrolase 3 family
AL504_26910	COG0322	excinuclease ABC activity
AL504_26915	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AL504_26925	COG0473	3-isopropylmalate dehydrogenase activity
AL504_26930	COG0583	DNA-binding transcription factor activity
AL504_26935	COG1858	cytochrome C peroxidase
AL504_26940	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AL504_26940	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AL504_26945	COG2224	Isocitrate lyase
AL504_26960	COG4106	trans-aconitate 2-methyltransferase activity
AL504_26960	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AL504_26970	COG0156	8-amino-7-oxononanoate synthase activity
AL504_26990	COG3278	Belongs to the heme-copper respiratory oxidase family
AL504_27010	COG0348	domain, Protein
AL504_27030	COG1012	belongs to the aldehyde dehydrogenase family
AL504_27035	COG1126	abc transporter atp-binding protein
AL504_27040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_27050	COG0765	amino acid transport
AL504_27055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL504_27090	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AL504_27100	COG0438	transferase activity, transferring glycosyl groups
AL504_27115	COG1538	Outer membrane efflux protein
AL504_27120	COG1566	PFAM secretion protein HlyD family protein
AL504_27135	COG0583	DNA-binding transcription factor activity
AL504_27140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL504_27145	COG0586	Pfam SNARE associated Golgi protein
AL504_27150	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL504_27165	COG4608	Belongs to the ABC transporter superfamily
AL504_27170	COG0444	Belongs to the ABC transporter superfamily
AL504_27175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL504_27180	COG0601	transmembrane transport
AL504_27185	COG0583	DNA-binding transcription factor activity
AL504_27190	COG0300	oxidoreductase activity
AL504_27195	COG1764	response to oxidative stress
AL504_27200	COG2205	protein histidine kinase activity
AL504_27205	COG0745	RESPONSE REGULATOR receiver
AL504_27225	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL504_27240	COG1802	Transcriptional regulator
AL504_27255	COG1595	DNA-templated transcription, initiation
AL504_27275	COG2084	Dehydrogenase
AL504_27285	COG1917	Cupin 2, conserved barrel domain protein
AL504_27285	COG2207	Transcriptional regulator
AL504_27295	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL504_27335	COG1280	lysine exporter protein (LysE YggA)
AL504_27340	COG1522	sequence-specific DNA binding
AL504_27360	COG1280	lysine exporter protein (LysE YggA)
AL504_27370	COG0745	RESPONSE REGULATOR receiver
AL504_27385	COG4774	siderophore transport
AL504_27390	COG3712	iron ion homeostasis
AL504_27395	COG1595	DNA-templated transcription, initiation
AL504_27400	COG0840	transmembrane signaling receptor activity
AL504_27405	COG3121	Chaperone
AL504_27410	COG3188	usher protein
AL504_27425	COG0745	RESPONSE REGULATOR receiver
AL504_27430	COG0642	Histidine kinase
AL504_27435	COG1475	DNA binding
AL504_27440	COG3969	phosphoadenosine phosphosulfate
AL504_27445	COG1971	Probably functions as a manganese efflux pump
AL504_27450	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL504_27505	COG2321	neutral zinc metallopeptidase
AL504_27510	COG0009	L-threonylcarbamoyladenylate synthase
AL504_27515	COG1994	Peptidase M50
AL504_27520	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL504_27525	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AL504_27535	COG2850	peptidyl-arginine hydroxylation
AL504_27540	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AL504_27575	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AL504_27585	COG0583	DNA-binding transcription factor activity
AL504_27610	COG2311	Membrane
AL504_27630	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_27635	COG0583	DNA-binding transcription factor activity
AL504_27645	COG3360	Dodecin
AL504_27680	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AL504_27685	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL504_27690	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL504_27730	COG0668	transmembrane transport
AL504_27750	COG0583	DNA-binding transcription factor activity
AL504_27775	COG4804	nuclease activity
AL504_27780	COG1477	protein flavinylation
AL504_27790	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AL504_27805	COG4263	nitrous-oxide reductase activity
AL504_27820	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AL504_27825	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AL504_27835	COG1253	flavin adenine dinucleotide binding
AL504_27840	COG1968	undecaprenyl-diphosphatase activity
AL504_27845	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL504_27860	COG0215	cysteine-tRNA ligase activity
AL504_27870	COG0825	malonyl-CoA metabolic process
AL504_27875	COG0037	tRNA processing
AL504_27880	COG0527	aspartate kinase activity
AL504_27895	COG0348	domain, Protein
AL504_27915	COG3278	Belongs to the heme-copper respiratory oxidase family
AL504_27930	COG3258	Cytochrome c
AL504_27935	COG2863	cytochrome
AL504_27940	COG2205	protein histidine kinase activity
AL504_27940	COG0784	Response regulator, receiver
AL504_27945	COG2200	EAL domain
AL504_27950	COG0784	Response regulator, receiver
AL504_27950	COG2205	protein histidine kinase activity
AL504_27955	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AL504_27965	COG1309	transcriptional regulator
AL504_27970	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AL504_28010	COG0583	DNA-binding transcription factor activity
AL504_28035	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AL504_28045	COG1414	Transcriptional regulator
AL504_28055	COG1024	Enoyl-CoA hydratase
AL504_28060	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AL504_28065	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AL504_28075	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AL504_28090	COG1132	(ABC) transporter
AL504_28100	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_28110	COG0318	PFAM AMP-dependent synthetase and ligase
AL504_28125	COG0183	Belongs to the thiolase family
AL504_28130	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL504_28130	COG1024	Enoyl-CoA hydratase
AL504_28140	COG1024	Enoyl-CoA hydratase
AL504_28140	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL504_28150	COG1960	acyl-CoA dehydrogenase activity
AL504_28155	COG1309	transcriptional regulator
AL504_28165	COG2197	response regulator
AL504_28170	COG2197	response regulator
AL504_28175	COG0297	glycogen (starch) synthase activity
AL504_28180	COG0110	maltose O-acetyltransferase activity
AL504_28185	COG0463	Glycosyl transferase, family 2
AL504_28210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL504_28255	COG0166	Belongs to the GPI family
AL504_28260	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AL504_28265	COG1045	serine acetyltransferase
AL504_28270	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AL504_28285	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL504_28305	COG0598	Magnesium transport protein CorA
AL504_28320	COG0601	transmembrane transport
AL504_28325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL504_28330	COG4172	Belongs to the ABC transporter superfamily
AL504_28340	COG1846	Transcriptional regulator
AL504_28385	COG4964	Belongs to the GSP D family
AL504_28440	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AL504_28455	COG3384	dioxygenase
AL504_28460	COG0583	DNA-binding transcription factor activity
AL504_28470	COG2814	Major facilitator Superfamily
AL504_28475	COG1566	PFAM secretion protein HlyD family protein
AL504_28490	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AL504_28490	COG2885	chlorophyll binding
AL504_28495	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AL504_28515	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_28520	COG3321	synthase
AL504_28520	COG0604	alcohol dehydrogenase
AL504_28520	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_28535	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL504_28545	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_28550	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL504_28555	COG3246	L-lysine catabolic process to acetate
AL504_28560	COG0371	Dehydrogenase
AL504_28565	COG1802	Transcriptional regulator
AL504_28570	COG3959	Transketolase, thiamine diphosphate binding domain
AL504_28575	COG3958	Transketolase
AL504_28580	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AL504_28590	COG4948	Mandelate Racemase Muconate Lactonizing
AL504_28605	COG0765	amino acid transport
AL504_28615	COG2721	sulfolactate sulfo-lyase activity
AL504_28625	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_28630	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL504_28635	COG1414	Transcriptional regulator
AL504_28675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL504_28705	COG4771	TonB-dependent receptor
AL504_28720	COG5295	Hep Hag repeat protein
AL504_28755	COG2198	Histidine kinase
AL504_28755	COG2205	protein histidine kinase activity
AL504_28755	COG0784	Response regulator, receiver
AL504_28755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_28760	COG0477	Major facilitator Superfamily
AL504_28770	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL504_28780	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL504_28800	COG1113	amino acid transport
AL504_28810	COG1640	4-alpha-glucanotransferase
AL504_28815	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AL504_28825	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AL504_28830	COG0366	Alpha amylase catalytic
AL504_28835	COG0366	Alpha amylase catalytic
AL504_28840	COG0297	glycogen (starch) synthase activity
AL504_28845	COG0392	lysyltransferase activity
AL504_28850	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL504_28855	COG3568	Endonuclease Exonuclease Phosphatase
AL504_28860	COG0387	Pfam Sodium calcium exchanger
AL504_28875	COG3685	Protein conserved in bacteria
AL504_28885	COG0166	Belongs to the GPI family
AL504_28895	COG0668	transmembrane transport
AL504_28965	COG1064	alcohol dehydrogenase
AL504_28980	COG1850	ribulose-bisphosphate carboxylase activity
AL504_28990	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL504_28995	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL504_29010	COG1012	belongs to the aldehyde dehydrogenase family
AL504_29015	COG0596	Alpha beta hydrolase
AL504_29040	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL504_29055	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_29065	COG0235	Class ii aldolase
AL504_29070	COG1396	sequence-specific DNA binding
AL504_29170	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AL504_29175	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AL504_29180	COG1116	anion transmembrane transporter activity
AL504_29185	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL504_29190	COG1116	anion transmembrane transporter activity
AL504_29190	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL504_29195	COG2197	response regulator
AL504_29205	COG1131	(ABC) transporter
AL504_29210	COG0842	Transport permease protein
AL504_29225	COG0183	Belongs to the thiolase family
AL504_29255	COG0318	PFAM AMP-dependent synthetase and ligase
AL504_29270	COG0604	alcohol dehydrogenase
AL504_29270	COG3321	synthase
AL504_29285	COG4638	Rieske (2fe-2S)
AL504_29315	COG1272	protein, Hemolysin III
AL504_29345	COG2169	Transcriptional regulator
AL504_29365	COG0583	DNA-binding transcription factor activity
AL504_29375	COG4172	Belongs to the ABC transporter superfamily
AL504_29380	COG0402	S-adenosylhomocysteine deaminase activity
AL504_29385	COG0747	negative chemotaxis
AL504_29390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL504_29400	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_29410	COG2814	Major facilitator Superfamily
AL504_29415	COG0583	DNA-binding transcription factor activity
AL504_29495	COG4126	flavin adenine dinucleotide binding
AL504_29510	COG2837	iron assimilation
AL504_29545	COG0583	DNA-binding transcription factor activity
AL504_29550	COG2814	Major facilitator Superfamily
AL504_29555	COG0583	DNA-binding transcription factor activity
AL504_29570	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL504_29585	COG2814	Major facilitator Superfamily
AL504_29595	COG1464	Belongs to the NlpA lipoprotein family
AL504_29600	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AL504_29605	COG2011	ABC-type metal ion transport system permease component
AL504_29640	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_29660	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
AL504_29665	COG0456	acetyltransferase
AL504_29665	COG0454	-acetyltransferase
AL504_29675	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_29680	COG1473	amidohydrolase
AL504_29695	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_29700	COG2272	Belongs to the type-B carboxylesterase lipase family
AL504_29705	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AL504_29710	COG0583	DNA-binding transcription factor activity
AL504_29725	COG2951	lytic endotransglycosylase activity
AL504_29735	COG0519	Catalyzes the synthesis of GMP from XMP
AL504_29740	COG0519	Catalyzes the synthesis of GMP from XMP
AL504_29750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL504_29775	COG1522	sequence-specific DNA binding
AL504_29790	COG3706	GGDEF domain
AL504_29825	COG0625	glutathione transferase activity
AL504_29840	COG3530	Putative quorum-sensing-regulated virulence factor
AL504_29850	COG2814	Major facilitator Superfamily
AL504_29885	COG0443	Heat shock 70 kDa protein
AL504_29890	COG0583	DNA-binding transcription factor activity
AL504_29910	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL504_29915	COG0477	Major facilitator Superfamily
AL504_29925	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL504_29935	COG0542	response to heat
AL504_29960	COG5441	Belongs to the UPF0261 family
AL504_29965	COG5564	TIM-barrel signal transduction protein
AL504_29980	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AL504_29995	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AL504_30005	COG1562	ergosterol biosynthetic process
AL504_30015	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AL504_30020	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_30030	COG3971	2-oxopent-4-enoate hydratase activity
AL504_30045	COG1012	belongs to the aldehyde dehydrogenase family
AL504_30050	COG3384	dioxygenase
AL504_30080	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL504_30090	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_30100	COG2186	Transcriptional regulator
AL504_30105	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AL504_30110	COG3181	Tripartite tricarboxylate transporter family receptor
AL504_30120	COG0019	diaminopimelate decarboxylase activity
AL504_30125	COG0583	DNA-binding transcription factor activity
AL504_30130	COG0268	Binds directly to 16S ribosomal RNA
AL504_30140	COG0728	peptidoglycan biosynthetic process
AL504_30150	COG0563	adenylate kinase activity
AL504_30155	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AL504_30160	COG2835	tetraacyldisaccharide 4'-kinase activity
AL504_30170	COG1663	tetraacyldisaccharide 4'-kinase activity
AL504_30180	COG0811	peptide transport
AL504_30185	COG1570	exodeoxyribonuclease VII activity
AL504_30195	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AL504_30210	COG0183	Belongs to the thiolase family
AL504_30220	COG1278	Cold shock
AL504_30225	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AL504_30230	COG2373	Large extracellular alpha-helical protein
AL504_30235	COG4953	penicillin-binding protein 1C
AL504_30245	COG2995	paraquat-inducible protein a
AL504_30250	COG3008	intermembrane lipid transfer
AL504_30260	COG0506	proline dehydrogenase activity
AL504_30260	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AL504_30260	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AL504_30270	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL504_30280	COG0411	ABC transporter
AL504_30305	COG2271	Major facilitator Superfamily
AL504_30325	COG1289	transmembrane transporter activity
AL504_30335	COG1566	PFAM secretion protein HlyD family protein
AL504_30350	COG0625	glutathione transferase activity
AL504_30365	COG1764	response to oxidative stress
AL504_30370	COG2423	ornithine cyclodeaminase activity
AL504_30380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL504_30385	COG0765	amino acid transport
AL504_30390	COG0765	amino acid transport
AL504_30395	COG1126	abc transporter atp-binding protein
AL504_30400	COG1902	pentaerythritol trinitrate reductase activity
AL504_30445	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AL504_30450	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AL504_30455	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AL504_30460	COG0196	riboflavin kinase activity
AL504_30465	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AL504_30470	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AL504_30470	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AL504_30485	COG0210	DNA helicase
AL504_30495	COG1858	cytochrome C peroxidase
AL504_30500	COG4771	TonB-dependent receptor
AL504_30505	COG4771	TonB-dependent receptor
AL504_30510	COG4771	TonB-dependent receptor
AL504_30525	COG0488	(ABC) transporter
AL504_30530	COG2890	protein-(glutamine-N5) methyltransferase activity
AL504_30540	COG2171	N-acyltransferase activity
AL504_30710	COG0740	serine-type endopeptidase activity
AL504_30860	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AL504_30875	COG3038	cytochrome b561
AL504_30880	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AL504_30930	COG0583	DNA-binding transcription factor activity
AL504_30940	COG0251	oxidation-reduction process
AL504_30965	COG1278	Cold shock
AL504_30975	COG1278	Cold shock
AL504_30985	COG0501	Belongs to the peptidase M48B family
AL504_30990	COG0544	peptidyl-prolyl cis-trans isomerase activity
AL504_30995	COG0740	serine-type endopeptidase activity
AL504_31000	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AL504_31005	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AL504_31010	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AL504_31020	COG0556	nucleotide-excision repair
AL504_31025	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AL504_31035	COG1104	cysteine desulfurase activity
AL504_31040	COG0822	iron-sulfur transferase activity
AL504_31045	COG0316	Belongs to the HesB IscA family
AL504_31050	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AL504_31055	COG0443	Heat shock 70 kDa protein
AL504_31060	COG0633	Ferredoxin
AL504_31065	COG2975	iron-sulfur cluster assembly
AL504_31070	COG1803	Methylglyoxal synthase
AL504_31080	COG1024	Enoyl-CoA hydratase
AL504_31105	COG0410	ABC transporter
AL504_31110	COG1022	Amp-dependent synthetase and ligase
AL504_31120	COG1309	transcriptional regulator
AL504_31150	COG3135	benzoate transporter
AL504_31165	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AL504_31170	COG1028	Short-chain dehydrogenase reductase Sdr
AL504_31180	COG2271	Major facilitator Superfamily
AL504_31200	COG1573	uracil-dna glycosylase
AL504_31245	COG3501	Rhs element vgr protein
AL504_31305	COG0840	transmembrane signaling receptor activity
AL504_31315	COG4774	siderophore transport
AL504_31320	COG1309	transcriptional regulator
AL504_31370	COG2814	Major facilitator Superfamily
AL504_31380	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL504_31465	COG0653	protein targeting
AL504_31485	COG2833	Protein of unknown function (DUF455)
AL504_31515	COG1399	metal-binding, possibly nucleic acid-binding protein
AL504_31520	COG1268	BioY protein
AL504_31535	COG0802	atpase or kinase
AL504_31550	COG0583	DNA-binding transcription factor activity
AL504_31590	COG3064	Membrane
AL504_31660	COG0210	DNA helicase
AL504_31670	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AL504_31675	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AL504_31730	COG3657	addiction module killer protein
AL504_31770	COG1686	Belongs to the peptidase S11 family
AL504_31800	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AL504_31820	COG1403	HNH endonuclease
AL504_31825	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AL504_31835	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP