locus-tag	class	description
AL509_00010	COG2345	Transcriptional regulator
AL509_00020	COG1414	Transcriptional regulator
AL509_00030	COG0477	Major facilitator Superfamily
AL509_00035	COG0667	Aldo Keto reductase
AL509_00045	COG3181	Tripartite tricarboxylate transporter family receptor
AL509_00050	COG1309	transcriptional regulator
AL509_00070	COG1683	Conserved Protein
AL509_00110	COG2885	chlorophyll binding
AL509_00110	COG3047	cAMP biosynthetic process
AL509_00125	COG3795	YCII-related domain
AL509_00130	COG3795	YCII-related domain
AL509_00140	COG4941	Belongs to the sigma-70 factor family
AL509_00150	COG0697	spore germination
AL509_00160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL509_00170	COG0583	DNA-binding transcription factor activity
AL509_00200	COG1846	Transcriptional regulator
AL509_00205	COG3541	Predicted nucleotidyltransferase
AL509_00225	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL509_00270	COG1360	Flagellar Motor Protein
AL509_00280	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
AL509_00340	COG3501	Rhs element vgr protein
AL509_00510	COG0024	Methionine aminopeptidase
AL509_00520	COG0625	glutathione transferase activity
AL509_00525	COG2032	superoxide dismutase activity
AL509_00530	COG2733	membrane
AL509_00540	COG0148	phosphopyruvate hydratase activity
AL509_00575	COG0583	DNA-binding transcription factor activity
AL509_00580	COG1024	Enoyl-CoA hydratase
AL509_00580	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL509_00585	COG0183	Belongs to the thiolase family
AL509_00590	COG1960	acyl-CoA dehydrogenase activity
AL509_00595	COG1960	acyl-CoA dehydrogenase activity
AL509_00600	COG0318	PFAM AMP-dependent synthetase and ligase
AL509_00610	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AL509_00625	COG0583	DNA-binding transcription factor activity
AL509_00635	COG1846	Transcriptional regulator
AL509_00640	COG0477	Major facilitator Superfamily
AL509_00660	COG0596	Alpha beta hydrolase
AL509_00665	COG2309	aminopeptidase activity
AL509_00670	COG1335	isochorismatase
AL509_00675	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AL509_00675	COG2010	Cytochrome c
AL509_00685	COG1522	sequence-specific DNA binding
AL509_00690	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL509_00695	COG3842	ATPase activity
AL509_00700	COG1840	ABC-type Fe3 transport system, periplasmic component
AL509_00710	COG3706	GGDEF domain
AL509_00710	COG4251	negative regulation of phosphorylation
AL509_00710	COG5001	Diguanylate cyclase
AL509_00710	COG2203	Gaf domain
AL509_00715	COG2201	protein-glutamate methylesterase activity
AL509_00740	COG0840	transmembrane signaling receptor activity
AL509_00745	COG0154	amidase activity
AL509_00765	COG0583	DNA-binding transcription factor activity
AL509_00795	COG0456	acetyltransferase
AL509_00810	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_00840	COG0477	Major facilitator Superfamily
AL509_00865	COG0165	Argininosuccinate lyase
AL509_00880	COG0583	DNA-binding transcription factor activity
AL509_00895	COG2205	protein histidine kinase activity
AL509_00915	COG4221	oxidoreductase activity
AL509_00920	COG2207	Transcriptional regulator
AL509_00950	COG0640	Transcriptional regulator
AL509_00955	COG0640	Transcriptional regulator
AL509_00965	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AL509_00970	COG0583	DNA-binding transcription factor activity
AL509_00975	COG0431	NADPH-dependent FMN reductase
AL509_00985	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AL509_01005	COG2207	Transcriptional regulator
AL509_01025	COG4264	IucA IucC family
AL509_01050	COG0556	nucleotide-excision repair
AL509_01070	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AL509_01070	COG0519	Catalyzes the synthesis of GMP from XMP
AL509_01095	COG0583	DNA-binding transcription factor activity
AL509_01105	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL509_01130	COG0583	DNA-binding transcription factor activity
AL509_01135	COG3181	Tripartite tricarboxylate transporter family receptor
AL509_01175	COG2072	flavoprotein involved in K transport
AL509_01180	COG0601	transmembrane transport
AL509_01185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL509_01195	COG4608	Belongs to the ABC transporter superfamily
AL509_01200	COG0747	negative chemotaxis
AL509_01220	COG0583	DNA-binding transcription factor activity
AL509_01225	COG3181	Tripartite tricarboxylate transporter family receptor
AL509_01230	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AL509_01235	COG3181	Tripartite tricarboxylate transporter family receptor
AL509_01275	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL509_01290	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL509_01300	COG0583	DNA-binding transcription factor activity
AL509_01345	COG5001	Diguanylate cyclase
AL509_01350	COG4774	siderophore transport
AL509_01365	COG0583	DNA-binding transcription factor activity
AL509_01415	COG1953	Uracil, thiamine, allantoin
AL509_01455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL509_01455	COG2205	protein histidine kinase activity
AL509_01455	COG2198	Histidine kinase
AL509_01455	COG0784	Response regulator, receiver
AL509_01490	COG3181	Tripartite tricarboxylate transporter family receptor
AL509_01495	COG0583	DNA-binding transcription factor activity
AL509_01500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL509_01515	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AL509_01530	COG0583	DNA-binding transcription factor activity
AL509_01545	COG0642	Histidine kinase
AL509_01550	COG0745	RESPONSE REGULATOR receiver
AL509_01570	COG1595	DNA-templated transcription, initiation
AL509_01575	COG3712	iron ion homeostasis
AL509_01590	COG0047	phosphoribosylformylglycinamidine synthase activity
AL509_01590	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AL509_01605	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL509_01655	COG0613	PHP domain protein
AL509_01670	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL509_01680	COG0583	DNA-binding transcription factor activity
AL509_01690	COG0583	DNA-binding transcription factor activity
AL509_01695	COG0477	Major facilitator Superfamily
AL509_01700	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL509_01710	COG0159	tryptophan synthase activity
AL509_01740	COG3093	addiction module antidote protein HigA
AL509_01765	COG2249	NAD(P)H dehydrogenase (quinone) activity
AL509_01775	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AL509_01780	COG0459	protein refolding
AL509_01805	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AL509_01810	COG0714	Associated with various cellular activities
AL509_01830	COG2304	oxidoreductase activity
AL509_01845	COG3119	arylsulfatase activity
AL509_01855	COG1280	lysine exporter protein (LysE YggA)
AL509_01885	COG0633	Ferredoxin
AL509_01890	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_01895	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_01900	COG4133	protoheme IX ABC transporter activity
AL509_01905	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL509_01945	COG4604	ABC transporter, ATP-binding protein
AL509_01950	COG4605	iron ion homeostasis
AL509_01955	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL509_01960	COG4607	ABC-type enterochelin transport system periplasmic component
AL509_01965	COG4771	TonB-dependent receptor
AL509_01980	COG0084	hydrolase, TatD family'
AL509_01985	COG1136	(ABC) transporter
AL509_02005	COG2271	Major facilitator Superfamily
AL509_02015	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_02020	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AL509_02035	COG3135	benzoate transporter
AL509_02040	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AL509_02045	COG1309	transcriptional regulator
AL509_02050	COG0183	Belongs to the thiolase family
AL509_02055	COG1022	Amp-dependent synthetase and ligase
AL509_02060	COG0410	ABC transporter
AL509_02085	COG1024	Enoyl-CoA hydratase
AL509_02095	COG1803	Methylglyoxal synthase
AL509_02100	COG2975	iron-sulfur cluster assembly
AL509_02105	COG0633	Ferredoxin
AL509_02110	COG0443	Heat shock 70 kDa protein
AL509_02115	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AL509_02120	COG0316	Belongs to the HesB IscA family
AL509_02125	COG0822	iron-sulfur transferase activity
AL509_02130	COG1104	cysteine desulfurase activity
AL509_02140	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AL509_02145	COG0556	nucleotide-excision repair
AL509_02155	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AL509_02160	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AL509_02165	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AL509_02170	COG0740	serine-type endopeptidase activity
AL509_02175	COG0544	peptidyl-prolyl cis-trans isomerase activity
AL509_02180	COG0501	Belongs to the peptidase M48B family
AL509_02190	COG1278	Cold shock
AL509_02200	COG1278	Cold shock
AL509_02220	COG0251	oxidation-reduction process
AL509_02230	COG0583	DNA-binding transcription factor activity
AL509_02265	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AL509_02280	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AL509_02290	COG0277	FAD linked oxidase domain protein
AL509_02300	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AL509_02305	COG2814	Major facilitator Superfamily
AL509_02340	COG2171	N-acyltransferase activity
AL509_02350	COG2890	protein-(glutamine-N5) methyltransferase activity
AL509_02355	COG0488	(ABC) transporter
AL509_02370	COG4771	TonB-dependent receptor
AL509_02375	COG4771	TonB-dependent receptor
AL509_02385	COG1858	cytochrome C peroxidase
AL509_02395	COG0210	DNA helicase
AL509_02410	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AL509_02410	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AL509_02420	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AL509_02425	COG0196	riboflavin kinase activity
AL509_02430	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AL509_02435	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AL509_02440	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AL509_02490	COG1902	pentaerythritol trinitrate reductase activity
AL509_02495	COG1126	abc transporter atp-binding protein
AL509_02500	COG0765	amino acid transport
AL509_02505	COG0765	amino acid transport
AL509_02510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL509_02520	COG2423	ornithine cyclodeaminase activity
AL509_02525	COG1764	response to oxidative stress
AL509_02530	COG1914	H( )-stimulated, divalent metal cation uptake system
AL509_02535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL509_02540	COG0625	glutathione transferase activity
AL509_02550	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AL509_02555	COG4771	TonB-dependent receptor
AL509_02570	COG2271	Major facilitator Superfamily
AL509_02580	COG0411	ABC transporter
AL509_02590	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL509_02600	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AL509_02600	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AL509_02600	COG0506	proline dehydrogenase activity
AL509_02610	COG3008	intermembrane lipid transfer
AL509_02615	COG2995	paraquat-inducible protein a
AL509_02625	COG4953	penicillin-binding protein 1C
AL509_02630	COG2373	Large extracellular alpha-helical protein
AL509_02635	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AL509_02645	COG0183	Belongs to the thiolase family
AL509_02650	COG0038	chloride channel
AL509_02660	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AL509_02670	COG1570	exodeoxyribonuclease VII activity
AL509_02675	COG0811	peptide transport
AL509_02685	COG1663	tetraacyldisaccharide 4'-kinase activity
AL509_02695	COG2835	tetraacyldisaccharide 4'-kinase activity
AL509_02700	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AL509_02705	COG0563	adenylate kinase activity
AL509_02715	COG0728	peptidoglycan biosynthetic process
AL509_02725	COG0268	Binds directly to 16S ribosomal RNA
AL509_02730	COG0583	DNA-binding transcription factor activity
AL509_02735	COG0019	diaminopimelate decarboxylase activity
AL509_02745	COG3181	Tripartite tricarboxylate transporter family receptor
AL509_02750	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AL509_02755	COG2186	Transcriptional regulator
AL509_02765	COG3181	Tripartite tricarboxylate transporter family receptor
AL509_02775	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL509_02805	COG3384	dioxygenase
AL509_02810	COG1012	belongs to the aldehyde dehydrogenase family
AL509_02825	COG3971	2-oxopent-4-enoate hydratase activity
AL509_02835	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_02840	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AL509_02845	COG1562	ergosterol biosynthetic process
AL509_02850	COG1562	ergosterol biosynthetic process
AL509_02860	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AL509_02885	COG1477	protein flavinylation
AL509_02900	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AL509_02915	COG5564	TIM-barrel signal transduction protein
AL509_02920	COG5441	Belongs to the UPF0261 family
AL509_02945	COG0542	response to heat
AL509_02955	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL509_02965	COG0477	Major facilitator Superfamily
AL509_02985	COG0494	nUDIX hydrolase
AL509_02990	COG0583	DNA-binding transcription factor activity
AL509_02995	COG0443	Heat shock 70 kDa protein
AL509_03030	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AL509_03035	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL509_03080	COG2837	iron assimilation
AL509_03090	COG0583	DNA-binding transcription factor activity
AL509_03095	COG2814	Major facilitator Superfamily
AL509_03100	COG2169	Transcriptional regulator
AL509_03130	COG1272	protein, Hemolysin III
AL509_03155	COG4638	Rieske (2fe-2S)
AL509_03215	COG0318	PFAM AMP-dependent synthetase and ligase
AL509_03245	COG0183	Belongs to the thiolase family
AL509_03260	COG0842	Transport permease protein
AL509_03265	COG1131	(ABC) transporter
AL509_03275	COG2197	response regulator
AL509_03280	COG1116	anion transmembrane transporter activity
AL509_03280	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL509_03285	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL509_03290	COG1116	anion transmembrane transporter activity
AL509_03295	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AL509_03300	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AL509_03315	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL509_03445	COG1396	sequence-specific DNA binding
AL509_03450	COG0235	Class ii aldolase
AL509_03460	COG3181	Tripartite tricarboxylate transporter family receptor
AL509_03505	COG4191	Histidine kinase
AL509_03510	COG3468	outer membrane autotransporter barrel domain protein
AL509_03520	COG0583	DNA-binding transcription factor activity
AL509_03615	COG1538	Outer membrane efflux protein
AL509_03625	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL509_03630	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AL509_03635	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AL509_03650	COG0505	Belongs to the CarA family
AL509_03665	COG3608	succinylglutamate desuccinylase aspartoacylase
AL509_03665	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AL509_03670	COG0583	DNA-binding transcription factor activity
AL509_03685	COG1064	alcohol dehydrogenase
AL509_03690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL509_03765	COG2192	nodulation
AL509_03775	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AL509_03780	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_03785	COG0438	transferase activity, transferring glycosyl groups
AL509_03795	COG5265	(ABC) transporter
AL509_03815	COG0668	transmembrane transport
AL509_03825	COG0166	Belongs to the GPI family
AL509_03845	COG0387	Pfam Sodium calcium exchanger
AL509_03850	COG3568	Endonuclease Exonuclease Phosphatase
AL509_03855	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL509_03860	COG0392	lysyltransferase activity
AL509_03890	COG0366	Alpha amylase catalytic
AL509_03895	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AL509_03905	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AL509_03910	COG1640	4-alpha-glucanotransferase
AL509_03920	COG1113	amino acid transport
AL509_03935	COG1058	Belongs to the CinA family
AL509_03935	COG1546	Belongs to the CinA family
AL509_03945	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL509_03955	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL509_03965	COG0477	Major facilitator Superfamily
AL509_03970	COG1595	DNA-templated transcription, initiation
AL509_03980	COG4774	siderophore transport
AL509_03990	COG4771	TonB-dependent receptor
AL509_04020	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL509_04080	COG1414	Transcriptional regulator
AL509_04085	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL509_04090	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_04100	COG2721	sulfolactate sulfo-lyase activity
AL509_04110	COG0765	amino acid transport
AL509_04125	COG4948	Mandelate Racemase Muconate Lactonizing
AL509_04135	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AL509_04140	COG3958	Transketolase
AL509_04145	COG3959	Transketolase, thiamine diphosphate binding domain
AL509_04150	COG1802	Transcriptional regulator
AL509_04155	COG0371	Dehydrogenase
AL509_04160	COG3246	L-lysine catabolic process to acetate
AL509_04165	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL509_04170	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_04180	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL509_04190	COG0410	ABC transporter
AL509_04195	COG0604	alcohol dehydrogenase
AL509_04195	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_04195	COG3321	synthase
AL509_04200	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_04230	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_04235	COG0583	DNA-binding transcription factor activity
AL509_04240	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AL509_04245	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AL509_04245	COG2885	chlorophyll binding
AL509_04270	COG2814	Major facilitator Superfamily
AL509_04295	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AL509_04350	COG4964	Belongs to the GSP D family
AL509_04395	COG1846	Transcriptional regulator
AL509_04400	COG4172	Belongs to the ABC transporter superfamily
AL509_04405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL509_04425	COG0598	Magnesium transport protein CorA
AL509_04445	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL509_04460	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AL509_04465	COG1045	serine acetyltransferase
AL509_04470	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AL509_04475	COG0166	Belongs to the GPI family
AL509_04480	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AL509_04485	COG0489	protein tyrosine kinase activity
AL509_04485	COG3206	protein involved in exopolysaccharide biosynthesis
AL509_04500	COG1051	belongs to the nudix hydrolase family
AL509_04520	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL509_04545	COG0463	Glycosyl transferase, family 2
AL509_04550	COG0110	maltose O-acetyltransferase activity
AL509_04555	COG0297	glycogen (starch) synthase activity
AL509_04560	COG2197	response regulator
AL509_04565	COG2197	response regulator
AL509_04575	COG1309	transcriptional regulator
AL509_04580	COG1960	acyl-CoA dehydrogenase activity
AL509_04590	COG1024	Enoyl-CoA hydratase
AL509_04590	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL509_04600	COG1024	Enoyl-CoA hydratase
AL509_04600	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL509_04605	COG0183	Belongs to the thiolase family
AL509_04620	COG0318	PFAM AMP-dependent synthetase and ligase
AL509_04630	COG3181	Tripartite tricarboxylate transporter family receptor
AL509_04640	COG1132	(ABC) transporter
AL509_04650	COG3395	kinase activity
AL509_04655	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AL509_04665	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AL509_04670	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AL509_04675	COG1024	Enoyl-CoA hydratase
AL509_04685	COG1414	Transcriptional regulator
AL509_04695	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AL509_04715	COG0583	DNA-binding transcription factor activity
AL509_04745	COG1116	anion transmembrane transporter activity
AL509_04750	COG1309	transcriptional regulator
AL509_04760	COG1051	belongs to the nudix hydrolase family
AL509_04765	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AL509_04780	COG2205	protein histidine kinase activity
AL509_04780	COG0784	Response regulator, receiver
AL509_04790	COG2205	protein histidine kinase activity
AL509_04790	COG0784	Response regulator, receiver
AL509_04805	COG2863	cytochrome
AL509_04810	COG3258	Cytochrome c
AL509_04815	COG3278	Belongs to the heme-copper respiratory oxidase family
AL509_04845	COG0527	aspartate kinase activity
AL509_04850	COG0037	tRNA processing
AL509_04855	COG0825	malonyl-CoA metabolic process
AL509_04865	COG0215	cysteine-tRNA ligase activity
AL509_04880	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL509_04885	COG1968	undecaprenyl-diphosphatase activity
AL509_04890	COG1253	flavin adenine dinucleotide binding
AL509_04905	COG4263	nitrous-oxide reductase activity
AL509_04920	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AL509_04930	COG1477	protein flavinylation
AL509_04935	COG4804	nuclease activity
AL509_04960	COG0668	transmembrane transport
AL509_05000	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL509_05005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL509_05010	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AL509_05045	COG3360	Dodecin
AL509_05055	COG0583	DNA-binding transcription factor activity
AL509_05060	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_05120	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AL509_05125	COG2850	peptidyl-arginine hydroxylation
AL509_05130	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AL509_05135	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL509_05140	COG1994	Peptidase M50
AL509_05145	COG0009	L-threonylcarbamoyladenylate synthase
AL509_05150	COG2321	neutral zinc metallopeptidase
AL509_05205	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL509_05210	COG3969	phosphoadenosine phosphosulfate
AL509_05215	COG1475	DNA binding
AL509_05220	COG0642	Histidine kinase
AL509_05225	COG0745	RESPONSE REGULATOR receiver
AL509_05240	COG3188	usher protein
AL509_05250	COG0840	transmembrane signaling receptor activity
AL509_05280	COG3387	PFAM Glycoside hydrolase 15-related
AL509_05295	COG0840	transmembrane signaling receptor activity
AL509_05300	COG3181	Tripartite tricarboxylate transporter family receptor
AL509_05305	COG1280	lysine exporter protein (LysE YggA)
AL509_05310	COG1518	maintenance of DNA repeat elements
AL509_05325	COG1857	crispr-associated protein
AL509_05350	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL509_05360	COG2207	Transcriptional regulator
AL509_05360	COG1917	Cupin 2, conserved barrel domain protein
AL509_05370	COG2084	Dehydrogenase
AL509_05395	COG1595	DNA-templated transcription, initiation
AL509_05405	COG1802	Transcriptional regulator
AL509_05420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL509_05440	COG0745	RESPONSE REGULATOR receiver
AL509_05445	COG2205	protein histidine kinase activity
AL509_05450	COG1764	response to oxidative stress
AL509_05460	COG0601	transmembrane transport
AL509_05465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL509_05470	COG0444	Belongs to the ABC transporter superfamily
AL509_05475	COG4608	Belongs to the ABC transporter superfamily
AL509_05490	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL509_05495	COG0586	Pfam SNARE associated Golgi protein
AL509_05500	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL509_05505	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AL509_05550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL509_05555	COG0765	amino acid transport
AL509_05565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL509_05575	COG1012	belongs to the aldehyde dehydrogenase family
AL509_05600	COG3181	Tripartite tricarboxylate transporter family receptor
AL509_05620	COG0348	domain, Protein
AL509_05640	COG3278	Belongs to the heme-copper respiratory oxidase family
AL509_05655	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AL509_05660	COG0156	8-amino-7-oxononanoate synthase activity
AL509_05690	COG2224	Isocitrate lyase
AL509_05695	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AL509_05695	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AL509_05700	COG1858	cytochrome C peroxidase
AL509_05705	COG0583	DNA-binding transcription factor activity
AL509_05710	COG0473	3-isopropylmalate dehydrogenase activity
AL509_05720	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AL509_05725	COG0322	excinuclease ABC activity
AL509_05730	COG1472	Belongs to the glycosyl hydrolase 3 family
AL509_05735	COG0736	holo-[acyl-carrier-protein] synthase activity
AL509_05740	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AL509_05745	COG1538	Outer membrane efflux protein
AL509_05750	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL509_05755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL509_05780	COG3842	ATPase activity
AL509_05785	COG4149	molybdate abc transporter
AL509_05790	COG0725	ABC transporter, periplasmic molybdate-binding protein
AL509_05795	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AL509_05815	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AL509_05825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL509_05835	COG4120	Belongs to the binding-protein-dependent transport system permease family
AL509_05845	COG0667	Aldo Keto reductase
AL509_05855	COG0318	PFAM AMP-dependent synthetase and ligase
AL509_05860	COG1024	Enoyl-CoA hydratase
AL509_05870	COG1802	Transcriptional regulator
AL509_05880	COG0183	Belongs to the thiolase family
AL509_05885	COG1960	acyl-CoA dehydrogenase activity
AL509_05890	COG1960	acyl-CoA dehydrogenase activity
AL509_05895	COG0583	DNA-binding transcription factor activity
AL509_05920	COG4213	ABC transporter substrate-binding protein
AL509_05925	COG1129	ABC transporter
AL509_05930	COG4214	carbohydrate transport
AL509_05935	COG2706	6-phosphogluconolactonase activity
AL509_05940	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL509_05955	COG3448	diguanylate cyclase activity
AL509_05955	COG4175	Glycine betaine
AL509_05960	COG4176	ABC-type proline glycine betaine transport system permease component
AL509_05970	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL509_05975	COG2814	Major facilitator Superfamily
AL509_05980	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AL509_05985	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AL509_06020	COG1686	Belongs to the peptidase S11 family
AL509_06030	COG1846	Transcriptional regulator
AL509_06035	COG2814	Major facilitator Superfamily
AL509_06040	COG0495	leucyl-tRNA aminoacylation
AL509_06055	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AL509_06075	COG0154	amidase activity
AL509_06085	COG0477	Major facilitator Superfamily
AL509_06095	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL509_06110	COG0583	DNA-binding transcription factor activity
AL509_06160	COG0583	DNA-binding transcription factor activity
AL509_06165	COG0427	acetyl-CoA hydrolase
AL509_06170	COG0583	DNA-binding transcription factor activity
AL509_06175	COG3264	Mechanosensitive ion channel
AL509_06175	COG1511	domain protein
AL509_06195	COG2176	DNA-directed DNA polymerase activity
AL509_06225	COG3842	ATPase activity
AL509_06230	COG1176	ABC-type spermidine putrescine transport system, permease component I
AL509_06235	COG1177	transmembrane transport
AL509_06240	COG3938	Belongs to the proline racemase family
AL509_06250	COG0517	IMP dehydrogenase activity
AL509_06280	COG0500	methyltransferase
AL509_06295	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AL509_06310	COG0667	Aldo Keto reductase
AL509_06315	COG2207	Transcriptional regulator
AL509_06320	COG0583	DNA-binding transcription factor activity
AL509_06325	COG1335	isochorismatase
AL509_06335	COG2841	Protein conserved in bacteria
AL509_06350	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL509_06355	COG0438	transferase activity, transferring glycosyl groups
AL509_06370	COG2814	Major facilitator Superfamily
AL509_06375	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AL509_06410	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AL509_06420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AL509_06425	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AL509_06435	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL509_06440	COG0840	transmembrane signaling receptor activity
AL509_06445	COG2233	PERMEase
AL509_06455	COG1840	ABC-type Fe3 transport system, periplasmic component
AL509_06480	COG4221	oxidoreductase activity
AL509_06490	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AL509_06495	COG0505	Belongs to the CarA family
AL509_06500	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AL509_06515	COG0745	RESPONSE REGULATOR receiver
AL509_06530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL509_06540	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL509_06545	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL509_06550	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AL509_06570	COG1074	ATP-dependent DNA helicase activity
AL509_06585	COG2070	2-Nitropropane dioxygenase
AL509_06605	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL509_06620	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL509_06625	COG0318	PFAM AMP-dependent synthetase and ligase
AL509_06645	COG1686	Belongs to the peptidase S11 family
AL509_06660	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AL509_06665	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AL509_06670	COG4974	Belongs to the 'phage' integrase family
AL509_06675	COG0583	DNA-binding transcription factor activity
AL509_06680	COG0028	Belongs to the TPP enzyme family
AL509_06725	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AL509_06760	COG0411	ABC transporter
AL509_06770	COG0028	Belongs to the TPP enzyme family
AL509_06775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL509_06790	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AL509_06795	COG1414	Transcriptional regulator
AL509_06800	COG0009	L-threonylcarbamoyladenylate synthase
AL509_06805	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AL509_06810	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AL509_06815	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AL509_06820	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AL509_06840	COG1301	dicarboxylic acid transport
AL509_06850	COG3454	Phosphonate metabolism
AL509_06855	COG4778	phosphonate C-P lyase system protein PhnL
AL509_06860	COG4107	phosphonate C-P lyase system protein PhnK
AL509_06865	COG3627	carbon phosphorus lyase activity
AL509_06870	COG3626	phosphonate metabolism
AL509_06875	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AL509_06880	COG3624	Phosphonate C-P lyase system protein PhnG
AL509_06885	COG2188	Transcriptional regulator
AL509_06890	COG3454	Phosphonate metabolism
AL509_06895	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AL509_06900	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AL509_06905	COG0583	DNA-binding transcription factor activity
AL509_06910	COG0405	Gamma-glutamyltransferase
AL509_06930	COG3639	organic phosphonate transmembrane transporter activity
AL509_06935	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AL509_06940	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AL509_06950	COG0640	Transcriptional regulator
AL509_06960	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AL509_06970	COG0739	heme binding
AL509_06980	COG0521	Mo-molybdopterin cofactor biosynthetic process
AL509_06990	COG0306	phosphate transporter
AL509_07025	COG0625	glutathione transferase activity
AL509_07045	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AL509_07050	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AL509_07065	COG0126	phosphoglycerate kinase activity
AL509_07070	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AL509_07075	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AL509_07085	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AL509_07090	COG2732	(Barnase) inhibitor
AL509_07100	COG0281	malic enzyme
AL509_07100	COG0280	phosphate acetyltransferase
AL509_07110	COG0436	Aminotransferase
AL509_07125	COG0741	lytic transglycosylase activity
AL509_07130	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AL509_07145	COG4575	ribosome binding
AL509_07155	COG1116	anion transmembrane transporter activity
AL509_07160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL509_07165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL509_07170	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AL509_07170	COG1648	precorrin-2 dehydrogenase activity
AL509_07175	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AL509_07180	COG2027	D-alanyl-D-alanine carboxypeptidase
AL509_07195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL509_07205	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AL509_07210	COG0343	queuine tRNA-ribosyltransferase activity
AL509_07215	COG1862	Preprotein translocase
AL509_07220	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL509_07225	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL509_07245	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AL509_07250	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AL509_07255	COG1702	phosphate starvation-inducible protein PhoH
AL509_07260	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AL509_07265	COG4535	Mg2 and Co2 transporter CorC
AL509_07270	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AL509_07275	COG0667	Aldo Keto reductase
AL509_07315	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AL509_07320	COG0697	spore germination
AL509_07330	COG0678	peroxiredoxin activity
AL509_07340	COG0412	Dienelactone hydrolase
AL509_07350	COG0315	cyclic pyranopterin monophosphate synthase activity
AL509_07360	COG0314	molybdopterin synthase activity
AL509_07365	COG0521	Mo-molybdopterin cofactor biosynthetic process
AL509_07370	COG0303	'Molybdopterin
AL509_07400	COG3383	formate dehydrogenase (NAD+) activity
AL509_07405	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AL509_07440	COG0583	DNA-binding transcription factor activity
AL509_07445	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AL509_07460	COG2205	protein histidine kinase activity
AL509_07465	COG0745	RESPONSE REGULATOR receiver
AL509_07480	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL509_07495	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_07515	COG2828	Protein conserved in bacteria
AL509_07520	COG0583	DNA-binding transcription factor activity
AL509_07525	COG0456	acetyltransferase
AL509_07570	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL509_07580	COG0411	ABC transporter
AL509_07585	COG0410	ABC transporter
AL509_07595	COG4774	siderophore transport
AL509_07615	COG4585	Histidine kinase
AL509_07620	COG0671	phosphoesterase, PA-phosphatase related
AL509_07635	COG1666	GTP binding
AL509_07640	COG1120	ATPase activity
AL509_07645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL509_07650	COG4558	Periplasmic binding protein
AL509_07655	COG3720	iron ion transport
AL509_07665	COG3712	iron ion homeostasis
AL509_07670	COG1595	DNA-templated transcription, initiation
AL509_07685	COG2378	regulation of single-species biofilm formation
AL509_07715	COG1113	amino acid transport
AL509_07725	COG1522	sequence-specific DNA binding
AL509_07730	COG1272	protein, Hemolysin III
AL509_07735	COG3191	aminopeptidase activity
AL509_07740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL509_07745	COG0765	amino acid transport
AL509_07755	COG4942	peptidase
AL509_07780	COG1999	signal sequence binding
AL509_07800	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AL509_07810	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AL509_07815	COG1845	cytochrome c oxidase, subunit III
AL509_07820	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AL509_07845	COG4772	TonB-dependent receptor
AL509_07865	COG0281	malic enzyme
AL509_07865	COG0280	phosphate acetyltransferase
AL509_07885	COG0697	spore germination
AL509_07920	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_07925	COG0583	DNA-binding transcription factor activity
AL509_07945	COG1396	sequence-specific DNA binding
AL509_07950	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL509_07975	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AL509_07980	COG0346	lactoylglutathione lyase activity
AL509_07990	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AL509_07995	COG1285	pathogenesis
AL509_08000	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_08015	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AL509_08030	COG3712	iron ion homeostasis
AL509_08035	COG1595	DNA-templated transcription, initiation
AL509_08040	COG4773	Receptor
AL509_08060	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL509_08065	COG0330	HflC and HflK could
AL509_08090	COG2807	transmembrane transport
AL509_08095	COG2207	Transcriptional regulator
AL509_08100	COG4106	trans-aconitate 2-methyltransferase activity
AL509_08115	COG0583	DNA-binding transcription factor activity
AL509_08150	COG3712	iron ion homeostasis
AL509_08175	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL509_08180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL509_08185	COG0477	Major facilitator Superfamily
AL509_08190	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AL509_08195	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AL509_08200	COG1845	cytochrome c oxidase, subunit III
AL509_08205	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AL509_08215	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL509_08220	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL509_08225	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL509_08235	COG2814	Major facilitator Superfamily
AL509_08250	COG0625	glutathione transferase activity
AL509_08305	COG3707	response regulator
AL509_08310	COG2146	nitrite reductase [NAD(P)H] activity
AL509_08310	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL509_08315	COG2146	nitrite reductase [NAD(P)H] activity
AL509_08315	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL509_08335	COG0667	Aldo Keto reductase
AL509_08355	COG0583	DNA-binding transcription factor activity
AL509_08360	COG0023	Translation Initiation Factor
AL509_08370	COG0456	acetyltransferase
AL509_08370	COG0454	-acetyltransferase
AL509_08375	COG0583	DNA-binding transcription factor activity
AL509_08380	COG4948	Mandelate Racemase Muconate Lactonizing
AL509_08410	COG0840	transmembrane signaling receptor activity
AL509_08415	COG2199	diguanylate cyclase activity
AL509_08415	COG2203	Gaf domain
AL509_08420	COG0640	Transcriptional regulator
AL509_08430	COG0740	serine-type endopeptidase activity
AL509_08435	COG2814	Major facilitator Superfamily
AL509_08465	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL509_08475	COG0596	Alpha beta hydrolase
AL509_08485	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL509_08495	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL509_08500	COG0583	DNA-binding transcription factor activity
AL509_08535	COG0028	Belongs to the TPP enzyme family
AL509_08555	COG1230	cation diffusion facilitator family transporter
AL509_08575	COG1132	(ABC) transporter
AL509_08585	COG1201	RNA secondary structure unwinding
AL509_08590	COG1793	dna ligase
AL509_08595	COG1793	dna ligase
AL509_08595	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AL509_08635	COG1960	acyl-CoA dehydrogenase activity
AL509_08645	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL509_08650	COG0697	spore germination
AL509_08660	COG3181	Tripartite tricarboxylate transporter family receptor
AL509_08675	COG0583	DNA-binding transcription factor activity
AL509_08680	COG0583	DNA-binding transcription factor activity
AL509_08715	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_08745	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL509_08750	COG2223	nitrite transmembrane transporter activity
AL509_08760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL509_08775	COG3386	PFAM SMP-30 Gluconolaconase
AL509_08780	COG3246	L-lysine catabolic process to acetate
AL509_08785	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL509_08800	COG0583	DNA-binding transcription factor activity
AL509_08805	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL509_08810	COG3181	Tripartite tricarboxylate transporter family receptor
AL509_08815	COG4948	Mandelate Racemase Muconate Lactonizing
AL509_08830	COG0318	PFAM AMP-dependent synthetase and ligase
AL509_08875	COG1595	DNA-templated transcription, initiation
AL509_08905	COG4172	Belongs to the ABC transporter superfamily
AL509_08930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL509_08945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL509_08985	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AL509_08990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL509_09005	COG0459	protein refolding
AL509_09015	COG1846	Transcriptional regulator
AL509_09060	COG1137	ATPase activity
AL509_09065	COG0410	ABC transporter
AL509_09070	COG0246	Mannitol dehydrogenase
AL509_09075	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AL509_09080	COG1252	NADH dehydrogenase
AL509_09085	COG0284	orotidine-5'-phosphate decarboxylase activity
AL509_09090	COG1546	Belongs to the CinA family
AL509_09105	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AL509_09110	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AL509_09135	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AL509_09140	COG3639	organic phosphonate transmembrane transporter activity
AL509_09145	COG3639	organic phosphonate transmembrane transporter activity
AL509_09185	COG0742	ribosomal rna small subunit methyltransferase
AL509_09190	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AL509_09195	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL509_09200	COG3135	benzoate transporter
AL509_09215	COG2814	Major facilitator Superfamily
AL509_09240	COG0012	GTP binding
AL509_09250	COG0193	aminoacyl-tRNA hydrolase activity
AL509_09255	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AL509_09260	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AL509_09270	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AL509_09275	COG0840	transmembrane signaling receptor activity
AL509_09280	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AL509_09290	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AL509_09315	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AL509_09325	COG0204	Acyl-transferase
AL509_09330	COG1368	sulfuric ester hydrolase activity
AL509_09335	COG2186	Transcriptional regulator
AL509_09345	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL509_09355	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL509_09365	COG2205	protein histidine kinase activity
AL509_09370	COG0745	RESPONSE REGULATOR receiver
AL509_09375	COG0277	FAD linked oxidase domain protein
AL509_09390	COG0166	Belongs to the GPI family
AL509_09410	COG0438	transferase activity, transferring glycosyl groups
AL509_09420	COG0438	transferase activity, transferring glycosyl groups
AL509_09445	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AL509_09450	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL509_09455	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
AL509_09465	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AL509_09480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL509_09500	COG0747	negative chemotaxis
AL509_09505	COG0601	transmembrane transport
AL509_09510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL509_09515	COG4172	Belongs to the ABC transporter superfamily
AL509_09520	COG0154	amidase activity
AL509_09535	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AL509_09535	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AL509_09540	COG0509	glycine decarboxylation via glycine cleavage system
AL509_09545	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AL509_09560	COG2081	HI0933 family
AL509_09565	COG1982	Orn Lys Arg decarboxylase major
AL509_09580	COG3706	GGDEF domain
AL509_09590	COG0717	Belongs to the dCTP deaminase family
AL509_09605	COG0489	protein tyrosine kinase activity
AL509_09615	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL509_09615	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL509_09635	COG2755	lipolytic protein G-D-S-L family
AL509_09635	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AL509_09645	COG0745	RESPONSE REGULATOR receiver
AL509_09650	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AL509_09670	COG2200	EAL domain
AL509_09690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL509_09695	COG1129	ABC transporter
AL509_09695	COG0842	Transport permease protein
AL509_09700	COG0842	Transport permease protein
AL509_09710	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_09715	COG0583	DNA-binding transcription factor activity
AL509_09720	COG0697	spore germination
AL509_09730	COG1271	oxidase subunit
AL509_09735	COG1294	oxidase, subunit
AL509_09740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL509_09775	COG3258	Cytochrome c
AL509_09785	COG0625	glutathione transferase activity
AL509_09790	COG2986	histidine ammonia-lyase
AL509_09795	COG1234	tRNA 3'-trailer cleavage
AL509_09800	COG0477	Major facilitator Superfamily
AL509_09805	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AL509_09820	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AL509_09860	COG1595	DNA-templated transcription, initiation
AL509_09865	COG3712	iron ion homeostasis
AL509_09875	COG0165	Argininosuccinate lyase
AL509_09880	COG2205	protein histidine kinase activity
AL509_09890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL509_09920	COG0477	Major facilitator Superfamily
AL509_09930	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_09935	COG3246	L-lysine catabolic process to acetate
AL509_09955	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AL509_09965	COG0154	amidase activity
AL509_10025	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL509_10030	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL509_10035	COG0583	DNA-binding transcription factor activity
AL509_10040	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AL509_10060	COG1652	LysM domain
AL509_10065	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AL509_10070	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL509_10085	COG0625	glutathione transferase activity
AL509_10105	COG1012	belongs to the aldehyde dehydrogenase family
AL509_10150	COG3550	peptidyl-serine autophosphorylation
AL509_10170	COG1414	Transcriptional regulator
AL509_10180	COG0800	Aldolase
AL509_10185	COG4948	Mandelate Racemase Muconate Lactonizing
AL509_10190	COG2271	Major facilitator Superfamily
AL509_10195	COG1131	(ABC) transporter
AL509_10215	COG2814	Major facilitator Superfamily
AL509_10220	COG0326	Molecular chaperone. Has ATPase activity
AL509_10230	COG2233	PERMEase
AL509_10245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL509_10250	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL509_10255	COG3246	L-lysine catabolic process to acetate
AL509_10265	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_10405	COG0583	DNA-binding transcription factor activity
AL509_10415	COG1695	Transcriptional regulator
AL509_10435	COG0477	Major facilitator Superfamily
AL509_10450	COG0277	FAD linked oxidase domain protein
AL509_10460	COG3842	ATPase activity
AL509_10465	COG1176	ABC-type spermidine putrescine transport system, permease component I
AL509_10485	COG0628	permease
AL509_10490	COG0583	DNA-binding transcription factor activity
AL509_10495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL509_10515	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
AL509_10525	COG2186	Transcriptional regulator
AL509_10535	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AL509_10545	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL509_10555	COG0411	ABC transporter
AL509_10560	COG0410	ABC transporter
AL509_10565	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_10570	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AL509_10585	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL509_10590	COG0583	DNA-binding transcription factor activity
AL509_10595	COG0129	dihydroxy-acid dehydratase activity
AL509_10605	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL509_10610	COG0583	DNA-binding transcription factor activity
AL509_10625	COG2200	EAL domain
AL509_10630	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AL509_10635	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AL509_10640	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL509_10645	COG2031	fatty acid transporter
AL509_10650	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_10655	COG1414	Transcriptional regulator
AL509_10665	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AL509_10680	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AL509_10700	COG0288	reversible hydration of carbon dioxide
AL509_10705	COG1802	Transcriptional regulator
AL509_10710	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_10720	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL509_10740	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_10755	COG0625	glutathione transferase activity
AL509_10770	COG0583	DNA-binding transcription factor activity
AL509_10780	COG0583	DNA-binding transcription factor activity
AL509_10785	COG0477	Major facilitator Superfamily
AL509_10830	COG1464	Belongs to the NlpA lipoprotein family
AL509_10845	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AL509_10850	COG2890	protein-(glutamine-N5) methyltransferase activity
AL509_10855	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AL509_10860	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AL509_10870	COG1280	lysine exporter protein (LysE YggA)
AL509_10875	COG1522	sequence-specific DNA binding
AL509_10895	COG3622	Belongs to the hyi family
AL509_10910	COG0477	Major facilitator Superfamily
AL509_10920	COG2186	Transcriptional regulator
AL509_10925	COG3395	kinase activity
AL509_10930	COG2084	Dehydrogenase
AL509_10935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL509_10940	COG3622	Belongs to the hyi family
AL509_10945	COG0235	Class ii aldolase
AL509_10995	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL509_11015	COG0142	geranyltranstransferase activity
AL509_11020	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AL509_11025	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AL509_11030	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AL509_11035	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AL509_11045	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL509_11050	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AL509_11060	COG2186	Transcriptional regulator
AL509_11065	COG3447	MASE1 domain protein
AL509_11065	COG5001	Diguanylate cyclase
AL509_11065	COG5002	protein histidine kinase activity
AL509_11070	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AL509_11075	COG0793	Belongs to the peptidase S41A family
AL509_11080	COG4942	peptidase
AL509_11085	COG0588	phosphoglycerate mutase activity
AL509_11095	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AL509_11100	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AL509_11105	COG3181	Tripartite tricarboxylate transporter family receptor
AL509_11120	COG2226	methyltransferase
AL509_11125	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AL509_11130	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AL509_11135	COG0569	domain protein
AL509_11140	COG2204	response regulator
AL509_11145	COG5000	phosphorelay sensor kinase activity
AL509_11155	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AL509_11155	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AL509_11160	COG1280	lysine exporter protein (LysE YggA)
AL509_11170	COG2076	Multidrug Resistance protein
AL509_11175	COG1733	regulation of RNA biosynthetic process
AL509_11195	COG0546	phosphoglycolate phosphatase activity
AL509_11205	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AL509_11210	COG0242	peptide deformylase activity
AL509_11215	COG0758	DNA mediated transformation
AL509_11230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL509_11235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL509_11240	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AL509_11245	COG3181	Tripartite tricarboxylate transporter family receptor
AL509_11260	COG1238	metal cluster binding
AL509_11265	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AL509_11270	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL509_11285	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AL509_11290	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AL509_11295	COG4988	ABC transporter
AL509_11305	COG1294	oxidase, subunit
AL509_11320	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AL509_11330	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AL509_11340	COG1137	ATPase activity
AL509_11345	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AL509_11355	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AL509_11360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL509_11375	COG1660	Displays ATPase and GTPase activities
AL509_11385	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AL509_11395	COG0792	nuclease activity
AL509_11400	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AL509_11410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL509_11420	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AL509_11430	COG1309	transcriptional regulator
AL509_11435	COG0471	metal ion transport
AL509_11440	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AL509_11445	COG0772	Belongs to the SEDS family
AL509_11450	COG0768	penicillin binding
AL509_11460	COG1792	Involved in formation and maintenance of cell shape
AL509_11465	COG1077	Cell shape determining protein MreB Mrl
AL509_11470	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AL509_11475	COG0154	amidase activity
AL509_11480	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AL509_11495	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AL509_11500	COG0708	Exodeoxyribonuclease III
AL509_11505	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AL509_11515	COG0583	DNA-binding transcription factor activity
AL509_11525	COG0583	DNA-binding transcription factor activity
AL509_11540	COG0411	ABC transporter
AL509_11550	COG1764	response to oxidative stress
AL509_11555	COG1846	Transcriptional regulator
AL509_11610	COG0640	Transcriptional regulator
AL509_11635	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AL509_11640	COG3189	MarR family transcriptional regulator
AL509_11660	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_11665	COG0352	thiamine-phosphate diphosphorylase activity
AL509_11665	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AL509_11665	COG0351	phosphomethylpyrimidine kinase
AL509_11680	COG0443	Heat shock 70 kDa protein
AL509_11700	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AL509_11705	COG0513	Belongs to the DEAD box helicase family
AL509_11715	COG0617	tRNA 3'-terminal CCA addition
AL509_11725	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AL509_11730	COG2308	Evidence 4 Homologs of previously reported genes of
AL509_11740	COG1305	Transglutaminase-like
AL509_11765	COG1950	PFAM Membrane protein of
AL509_11770	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AL509_11775	COG0438	transferase activity, transferring glycosyl groups
AL509_11790	COG0066	3-isopropylmalate dehydratase activity
AL509_11805	COG0583	DNA-binding transcription factor activity
AL509_11815	COG0477	Major facilitator Superfamily
AL509_11820	COG0154	amidase activity
AL509_11825	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AL509_11840	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AL509_11850	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AL509_11855	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AL509_11865	COG0803	Belongs to the bacterial solute-binding protein 9 family
AL509_11880	COG0735	belongs to the Fur family
AL509_11885	COG0523	cobalamin synthesis protein
AL509_11890	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AL509_11895	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AL509_11900	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AL509_11910	COG2096	Adenosyltransferase
AL509_11920	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AL509_11935	COG0321	lipoyl(octanoyl) transferase activity
AL509_11940	COG2921	Belongs to the UPF0250 family
AL509_11950	COG1686	Belongs to the peptidase S11 family
AL509_11975	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AL509_11985	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AL509_11995	COG0859	PFAM glycosyl transferase family 9
AL509_12090	COG0463	Glycosyl transferase, family 2
AL509_12100	COG2814	Major facilitator Superfamily
AL509_12105	COG0697	spore germination
AL509_12130	COG3568	Endonuclease Exonuclease Phosphatase
AL509_12135	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AL509_12160	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL509_12175	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL509_12180	COG1956	GAF domain-containing protein
AL509_12185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL509_12210	COG2186	Transcriptional regulator
AL509_12215	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AL509_12245	COG4106	trans-aconitate 2-methyltransferase activity
AL509_12250	COG0629	single-stranded DNA binding
AL509_12255	COG2814	Major facilitator Superfamily
AL509_12265	COG0625	glutathione transferase activity
AL509_12270	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AL509_12275	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AL509_12280	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AL509_12290	COG1965	Belongs to the frataxin family
AL509_12295	COG0019	diaminopimelate decarboxylase activity
AL509_12305	COG1333	cytochrome c biogenesis protein
AL509_12315	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AL509_12330	COG4232	protein-disulfide reductase activity
AL509_12335	COG1324	tolerance protein
AL509_12345	COG0203	ribosomal protein L17
AL509_12350	COG0202	RNA polymerase activity
AL509_12355	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AL509_12360	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AL509_12365	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AL509_12370	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AL509_12375	COG0201	protein transport
AL509_12380	COG0200	Binds to the 23S rRNA
AL509_12385	COG1841	ribosomal large subunit assembly
AL509_12390	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AL509_12395	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AL509_12400	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AL509_12405	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AL509_12410	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AL509_12415	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AL509_12420	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AL509_12425	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AL509_12440	COG2207	Transcriptional regulator
AL509_12455	COG0411	ABC transporter
AL509_12460	COG0410	ABC transporter
AL509_12465	COG4177	L-phenylalanine transmembrane transporter activity
AL509_12480	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AL509_12485	COG0255	Belongs to the universal ribosomal protein uL29 family
AL509_12490	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AL509_12495	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AL509_12500	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AL509_12505	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AL509_12510	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AL509_12515	COG0089	rRNA binding
AL509_12520	COG0088	Forms part of the polypeptide exit tunnel
AL509_12525	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AL509_12530	COG0051	transcription antitermination factor activity, RNA binding
AL509_12535	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AL509_12540	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AL509_12545	COG0049	tRNA binding
AL509_12550	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AL509_12555	COG0745	RESPONSE REGULATOR receiver
AL509_12570	COG5002	protein histidine kinase activity
AL509_12585	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AL509_12590	COG0085	RNA polymerase activity
AL509_12595	COG0222	ribosome binding
AL509_12600	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AL509_12605	COG0081	regulation of translation
AL509_12610	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AL509_12620	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AL509_12630	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AL509_12670	COG1840	ABC-type Fe3 transport system, periplasmic component
AL509_12675	COG3842	ATPase activity
AL509_12685	COG1349	DNA-binding transcription factor activity
AL509_12710	COG0583	DNA-binding transcription factor activity
AL509_12715	COG0252	asparaginase activity
AL509_12720	COG1475	DNA binding
AL509_12730	COG1192	Involved in chromosome partitioning
AL509_12735	COG0357	Ribosomal RNA small subunit methyltransferase G
AL509_12740	COG0445	tRNA wobble uridine modification
AL509_12745	COG1278	Cold shock
AL509_12750	COG3180	Ammonia monooxygenase
AL509_12755	COG0436	Aminotransferase
AL509_12785	COG0038	chloride channel
AL509_12795	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AL509_12805	COG0601	transmembrane transport
AL509_12810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL509_12815	COG0444	Belongs to the ABC transporter superfamily
AL509_12820	COG4608	Belongs to the ABC transporter superfamily
AL509_12825	COG1473	amidohydrolase
AL509_12840	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AL509_12845	COG0753	catalase activity
AL509_12860	COG0594	ribonuclease P activity
AL509_12865	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AL509_12875	COG0592	DNA-directed DNA polymerase activity
AL509_12885	COG2814	Major facilitator Superfamily
AL509_12890	COG0583	DNA-binding transcription factor activity
AL509_12895	COG0583	DNA-binding transcription factor activity
AL509_12920	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AL509_12930	COG0583	DNA-binding transcription factor activity
AL509_12935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL509_12940	COG0765	amino acid transport
AL509_12945	COG0765	amino acid transport
AL509_12950	COG1126	abc transporter atp-binding protein
AL509_12965	COG1254	Belongs to the acylphosphatase family
AL509_12975	COG1304	FMN binding
AL509_12990	COG1176	ABC-type spermidine putrescine transport system, permease component I
AL509_12995	COG1177	transmembrane transport
AL509_13050	COG1609	Transcriptional regulator
AL509_13060	COG3842	ATPase activity
AL509_13065	COG1176	ABC-type spermidine putrescine transport system, permease component I
AL509_13070	COG1177	transmembrane transport
AL509_13095	COG0251	oxidation-reduction process
AL509_13100	COG0402	S-adenosylhomocysteine deaminase activity
AL509_13120	COG1744	ABC transporter substrate-binding protein PnrA-like
AL509_13130	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AL509_13145	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL509_13160	COG2814	Major facilitator Superfamily
AL509_13165	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AL509_13175	COG3781	membrane
AL509_13180	COG1522	sequence-specific DNA binding
AL509_13185	COG0028	Belongs to the TPP enzyme family
AL509_13190	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_13195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL509_13200	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AL509_13220	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL509_13225	COG2922	Belongs to the Smg family
AL509_13255	COG0765	amino acid transport
AL509_13260	COG0765	amino acid transport
AL509_13265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL509_13275	COG3181	Tripartite tricarboxylate transporter family receptor
AL509_13280	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AL509_13350	COG4977	sequence-specific DNA binding
AL509_13360	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
AL509_13400	COG2186	Transcriptional regulator
AL509_13405	COG2814	Major facilitator Superfamily
AL509_13415	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AL509_13460	COG1595	DNA-templated transcription, initiation
AL509_13465	COG0318	PFAM AMP-dependent synthetase and ligase
AL509_13480	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_13490	COG3181	Tripartite tricarboxylate transporter family receptor
AL509_13530	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AL509_13535	COG0183	Belongs to the thiolase family
AL509_13540	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AL509_13545	COG1960	acyl-CoA dehydrogenase activity
AL509_13550	COG1473	amidohydrolase
AL509_13560	COG1742	UPF0060 membrane protein
AL509_13575	COG1280	lysine exporter protein (LysE YggA)
AL509_13600	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL509_13610	COG0018	arginyl-trna synthetase
AL509_13625	COG0395	ABC-type sugar transport system, permease component
AL509_13630	COG1175	transmembrane transport
AL509_13635	COG1653	transport
AL509_13640	COG3842	ATPase activity
AL509_13645	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AL509_13650	COG1609	Transcriptional regulator
AL509_13660	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL509_13675	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AL509_13685	COG0583	DNA-binding transcription factor activity
AL509_13705	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AL509_13710	COG1280	lysine exporter protein (LysE YggA)
AL509_13715	COG0513	Belongs to the DEAD box helicase family
AL509_13720	COG5339	Protein conserved in bacteria
AL509_13725	COG5339	Protein conserved in bacteria
AL509_13730	COG1228	amidohydrolase
AL509_13740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL509_13745	COG0601	transmembrane transport
AL509_13750	COG0747	negative chemotaxis
AL509_13755	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AL509_13765	COG3708	Transcriptional regulator
AL509_13765	COG2207	Transcriptional regulator
AL509_13785	COG0583	DNA-binding transcription factor activity
AL509_13825	COG2969	positive regulation of protein catabolic process
AL509_13830	COG0625	glutathione transferase activity
AL509_13835	COG2857	Cytochrome c1
AL509_13840	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AL509_13845	COG0723	plastoquinol--plastocyanin reductase activity
AL509_13850	COG1970	mechanosensitive ion channel activity
AL509_13860	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AL509_13865	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL509_13880	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AL509_13885	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AL509_13890	COG0537	adenosine 5'-monophosphoramidase activity
AL509_13895	COG0140	phosphoribosyl-ATP diphosphatase activity
AL509_13900	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AL509_13905	COG0107	imidazoleglycerol-phosphate synthase activity
AL509_13910	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AL509_13915	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AL509_13920	COG0131	Imidazoleglycerol-phosphate dehydratase
AL509_13925	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AL509_13930	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AL509_13935	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AL509_13940	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AL509_13950	COG0842	Transport permease protein
AL509_13955	COG1131	(ABC) transporter
AL509_13965	COG2853	Lipoprotein
AL509_13970	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AL509_13975	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AL509_13980	COG1127	ABC transporter
AL509_13985	COG2070	2-Nitropropane dioxygenase
AL509_13995	COG0477	Major facilitator Superfamily
AL509_14010	COG0583	DNA-binding transcription factor activity
AL509_14015	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AL509_14020	COG0511	ligase activity, forming carbon-carbon bonds
AL509_14050	COG0067	glutamate synthase
AL509_14050	COG0070	glutamate synthase
AL509_14050	COG0069	glutamate synthase activity
AL509_14075	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AL509_14095	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AL509_14125	COG1612	heme a metabolic process
AL509_14130	COG0109	protoheme IX farnesyltransferase activity
AL509_14135	COG1999	signal sequence binding
AL509_14155	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AL509_14160	COG2814	Major facilitator Superfamily
AL509_14170	COG0438	transferase activity, transferring glycosyl groups
AL509_14180	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AL509_14190	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AL509_14210	COG4774	siderophore transport
AL509_14215	COG4592	Periplasmic binding protein
AL509_14220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL509_14225	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL509_14230	COG1120	ATPase activity
AL509_14250	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AL509_14275	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AL509_14280	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AL509_14285	COG2814	Major facilitator Superfamily
AL509_14290	COG0583	DNA-binding transcription factor activity
AL509_14300	COG2423	ornithine cyclodeaminase activity
AL509_14305	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AL509_14310	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AL509_14320	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL509_14330	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AL509_14335	COG0463	Glycosyl transferase, family 2
AL509_14385	COG0737	Belongs to the 5'-nucleotidase family
AL509_14400	COG2188	Transcriptional regulator
AL509_14410	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AL509_14415	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AL509_14430	COG0840	transmembrane signaling receptor activity
AL509_14435	COG2814	Major facilitator Superfamily
AL509_14450	COG3188	usher protein
AL509_14510	COG1802	Transcriptional regulator
AL509_14520	COG3069	C4-dicarboxylate transmembrane transporter activity
AL509_14525	COG1012	belongs to the aldehyde dehydrogenase family
AL509_14550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL509_14560	COG0747	negative chemotaxis
AL509_14585	COG1464	Belongs to the NlpA lipoprotein family
AL509_14590	COG0431	NADPH-dependent FMN reductase
AL509_14595	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL509_14600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL509_14605	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL509_14620	COG2011	ABC-type metal ion transport system permease component
AL509_14625	COG1464	Belongs to the NlpA lipoprotein family
AL509_14630	COG1116	anion transmembrane transporter activity
AL509_14635	COG3585	molybdate ion transport
AL509_14640	COG3064	Membrane
AL509_14665	COG1607	acyl-coa hydrolase
AL509_14675	COG0243	molybdopterin cofactor binding
AL509_14675	COG3383	formate dehydrogenase (NAD+) activity
AL509_14680	COG0243	molybdopterin cofactor binding
AL509_14680	COG3383	formate dehydrogenase (NAD+) activity
AL509_14685	COG0437	4 iron, 4 sulfur cluster binding
AL509_14690	COG2864	formate dehydrogenase
AL509_14705	COG3276	selenocysteine insertion sequence binding
AL509_14715	COG1215	transferase activity, transferring glycosyl groups
AL509_14720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL509_14725	COG1305	Transglutaminase-like
AL509_14730	COG0709	Synthesizes selenophosphate from selenide and ATP
AL509_14760	COG1012	belongs to the aldehyde dehydrogenase family
AL509_14765	COG3284	Transcriptional regulator
AL509_14770	COG0134	indole-3-glycerol-phosphate synthase activity
AL509_14775	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AL509_14780	COG0512	Glutamine amidotransferase of anthranilate synthase
AL509_14790	COG0546	phosphoglycolate phosphatase activity
AL509_14800	COG2967	ApaG domain
AL509_14810	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL509_14815	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL509_14825	COG0037	tRNA processing
AL509_14835	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AL509_14850	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL509_14855	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL509_14870	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL509_14895	COG3473	Maleate cis-trans isomerase
AL509_14900	COG0583	DNA-binding transcription factor activity
AL509_14915	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AL509_14930	COG1024	Enoyl-CoA hydratase
AL509_14945	COG0356	it plays a direct role in the translocation of protons across the membrane
AL509_14955	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AL509_14960	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AL509_14965	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AL509_14970	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AL509_14975	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AL509_14980	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AL509_14990	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AL509_14995	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AL509_15000	COG0210	DNA helicase
AL509_15015	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AL509_15030	COG2171	N-acyltransferase activity
AL509_15035	COG2195	Cleaves the N-terminal amino acid of tripeptides
AL509_15045	COG4608	Belongs to the ABC transporter superfamily
AL509_15050	COG0444	Belongs to the ABC transporter superfamily
AL509_15060	COG0601	transmembrane transport
AL509_15065	COG0747	negative chemotaxis
AL509_15070	COG2988	succinylglutamate desuccinylase activity
AL509_15080	COG0583	DNA-binding transcription factor activity
AL509_15085	COG0747	negative chemotaxis
AL509_15095	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AL509_15100	COG1024	Enoyl-CoA hydratase
AL509_15105	COG1024	Enoyl-CoA hydratase
AL509_15115	COG1309	transcriptional regulator
AL509_15130	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL509_15145	COG2814	Major facilitator Superfamily
AL509_15160	COG1764	response to oxidative stress
AL509_15165	COG0583	DNA-binding transcription factor activity
AL509_15175	COG1595	DNA-templated transcription, initiation
AL509_15180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL509_15185	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL509_15200	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL509_15210	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL509_15220	COG1129	ABC transporter
AL509_15235	COG1802	Transcriptional regulator
AL509_15245	COG0583	DNA-binding transcription factor activity
AL509_15255	COG2988	succinylglutamate desuccinylase activity
AL509_15265	COG2918	glutathione biosynthetic process
AL509_15295	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AL509_15300	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL509_15310	COG2721	sulfolactate sulfo-lyase activity
AL509_15315	COG2721	sulfolactate sulfo-lyase activity
AL509_15320	COG2188	Transcriptional regulator
AL509_15325	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AL509_15330	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AL509_15330	COG2813	Specifically methylates the guanine in position
AL509_15335	COG2223	nitrite transmembrane transporter activity
AL509_15345	COG2860	membrane
AL509_15350	COG1802	Transcriptional regulator
AL509_15355	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AL509_15360	COG1984	allophanate hydrolase subunit 2
AL509_15365	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AL509_15375	COG0583	DNA-binding transcription factor activity
AL509_15385	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL509_15400	COG2132	Multicopper oxidase
AL509_15425	COG0745	RESPONSE REGULATOR receiver
AL509_15430	COG2226	methyltransferase
AL509_15445	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AL509_15455	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AL509_15465	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AL509_15470	COG0351	phosphomethylpyrimidine kinase
AL509_15475	COG2022	thiamine diphosphate biosynthetic process
AL509_15480	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL509_15485	COG4771	TonB-dependent receptor
AL509_15495	COG2186	Transcriptional regulator
AL509_15510	COG1063	alcohol dehydrogenase
AL509_15520	COG0765	amino acid transport
AL509_15525	COG1126	abc transporter atp-binding protein
AL509_15530	COG4948	Mandelate Racemase Muconate Lactonizing
AL509_15535	COG0246	Mannitol dehydrogenase
AL509_15550	COG1194	a g-specific adenine glycosylase
AL509_15570	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AL509_15575	COG2177	Part of the ABC transporter FtsEX involved in
AL509_15585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL509_15590	COG4597	amino acid ABC transporter
AL509_15595	COG0765	amino acid transport
AL509_15600	COG1126	abc transporter atp-binding protein
AL509_15620	COG0410	ABC transporter
AL509_15625	COG1129	ABC transporter
AL509_15630	COG4177	L-phenylalanine transmembrane transporter activity
AL509_15635	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL509_15645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL509_15650	COG2081	HI0933 family
AL509_15660	COG0077	Prephenate dehydratase
AL509_15660	COG1605	Chorismate mutase
AL509_15690	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AL509_15695	COG0477	Major facilitator Superfamily
AL509_15705	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AL509_15710	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AL509_15730	COG0237	dephospho-CoA kinase activity
AL509_15735	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AL509_15760	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL509_15765	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AL509_15780	COG3833	ABC-type maltose transport systems, permease component
AL509_15785	COG1175	transmembrane transport
AL509_15790	COG3842	ATPase activity
AL509_15810	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AL509_15830	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL509_15845	COG0410	ABC transporter
AL509_15865	COG3706	GGDEF domain
AL509_15880	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_15885	COG1024	Enoyl-CoA hydratase
AL509_15925	COG4638	Rieske (2fe-2S)
AL509_15930	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AL509_15935	COG1335	isochorismatase
AL509_15940	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_15950	COG0741	lytic transglycosylase activity
AL509_15955	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AL509_15975	COG1678	Uncharacterized ACR, COG1678
AL509_15980	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AL509_15990	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AL509_16005	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AL509_16015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL509_16025	COG0765	amino acid transport
AL509_16030	COG1126	abc transporter atp-binding protein
AL509_16035	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AL509_16045	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AL509_16050	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AL509_16060	COG3842	ATPase activity
AL509_16065	COG1175	transmembrane transport
AL509_16075	COG0642	Histidine kinase
AL509_16085	COG0557	exoribonuclease II activity
AL509_16090	COG3150	esterase
AL509_16095	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AL509_16100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL509_16105	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AL509_16110	COG0511	ligase activity, forming carbon-carbon bonds
AL509_16115	COG0439	Biotin carboxylase
AL509_16120	COG2264	protein methyltransferase activity
AL509_16130	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AL509_16130	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AL509_16155	COG1696	Membrane protein involved in D-alanine export
AL509_16190	COG1522	sequence-specific DNA binding
AL509_16195	COG3181	Tripartite tricarboxylate transporter family receptor
AL509_16205	COG0583	DNA-binding transcription factor activity
AL509_16220	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL509_16225	COG1042	CoA-binding domain protein
AL509_16225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL509_16225	COG0045	succinate-CoA ligase (ADP-forming) activity
AL509_16230	COG1335	isochorismatase
AL509_16235	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL509_16240	COG1116	anion transmembrane transporter activity
AL509_16255	COG3028	Belongs to the UPF0307 family
AL509_16260	COG0312	modulator of DNA gyrase
AL509_16265	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AL509_16275	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL509_16280	COG4177	L-phenylalanine transmembrane transporter activity
AL509_16295	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AL509_16300	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AL509_16305	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AL509_16315	COG0316	Belongs to the HesB IscA family
AL509_16320	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AL509_16330	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AL509_16340	COG1280	lysine exporter protein (LysE YggA)
AL509_16345	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AL509_16350	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AL509_16365	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL509_16365	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL509_16380	COG2766	serine protein kinase
AL509_16385	COG2718	Belongs to the UPF0229 family
AL509_16390	COG2719	SpoVR family
AL509_16400	COG0583	DNA-binding transcription factor activity
AL509_16405	COG1942	4-Oxalocrotonate Tautomerase
AL509_16415	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL509_16425	COG3181	Tripartite tricarboxylate transporter family receptor
AL509_16470	COG4789	Type iii secretion
AL509_16530	COG4669	(LipO)protein
AL509_16560	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AL509_16565	COG4790	Type iii secretion
AL509_16570	COG4794	Type iii secretion
AL509_16575	COG4791	protein targeting
AL509_16580	COG4792	protein secretion
AL509_16615	COG2770	Histidine kinase
AL509_16615	COG2208	phosphoserine phosphatase activity
AL509_16625	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AL509_16630	COG2172	sigma factor antagonist activity
AL509_16635	COG1366	Belongs to the anti-sigma-factor antagonist family
AL509_16670	COG1388	LysM domain
AL509_16670	COG0741	lytic transglycosylase activity
AL509_16675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL509_16680	COG2226	methyltransferase
AL509_16685	COG0328	RNA-DNA hybrid ribonuclease activity
AL509_16695	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL509_16700	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AL509_16710	COG1671	Belongs to the UPF0178 family
AL509_16725	COG0786	glutamate:sodium symporter activity
AL509_16735	COG0463	Glycosyl transferase, family 2
AL509_16740	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AL509_16755	COG0583	DNA-binding transcription factor activity
AL509_16775	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL509_16795	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL509_16805	COG0583	DNA-binding transcription factor activity
AL509_16815	COG1346	cytolysis
AL509_16825	COG0697	spore germination
AL509_16830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL509_16845	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AL509_16855	COG1522	sequence-specific DNA binding
AL509_16870	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AL509_16875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL509_16890	COG0823	Involved in the tonB-independent uptake of proteins
AL509_16900	COG0848	biopolymer transport protein
AL509_16905	COG0811	peptide transport
AL509_16910	COG0824	Thioesterase
AL509_16915	COG0442	prolyl-tRNA aminoacylation
AL509_16945	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL509_16955	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AL509_16960	COG2084	Dehydrogenase
AL509_16965	COG0405	Gamma-glutamyltransferase
AL509_17005	COG0129	dihydroxy-acid dehydratase activity
AL509_17010	COG4654	Cytochrome c, class I
AL509_17015	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL509_17025	COG1522	sequence-specific DNA binding
AL509_17065	COG0583	DNA-binding transcription factor activity
AL509_17075	COG1473	amidohydrolase
AL509_17080	COG0418	dihydroorotase activity
AL509_17095	COG2001	Belongs to the MraZ family
AL509_17115	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AL509_17120	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL509_17125	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AL509_17135	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AL509_17140	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AL509_17145	COG1181	Belongs to the D-alanine--D-alanine ligase family
AL509_17150	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AL509_17160	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AL509_17165	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AL509_17175	COG0739	heme binding
AL509_17180	COG0653	protein targeting
AL509_17195	COG3181	Tripartite tricarboxylate transporter family receptor
AL509_17200	COG0028	Belongs to the TPP enzyme family
AL509_17210	COG0300	oxidoreductase activity
AL509_17215	COG1522	sequence-specific DNA binding
AL509_17230	COG2239	Acts as a magnesium transporter
AL509_17235	COG1607	acyl-coa hydrolase
AL509_17240	COG2855	membrane
AL509_17245	COG0583	DNA-binding transcription factor activity
AL509_17250	COG1473	amidohydrolase
AL509_17255	COG0318	PFAM AMP-dependent synthetase and ligase
AL509_17260	COG0483	inositol monophosphate 1-phosphatase activity
AL509_17270	COG1501	Belongs to the glycosyl hydrolase 31 family
AL509_17275	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AL509_17280	COG2011	ABC-type metal ion transport system permease component
AL509_17295	COG1595	DNA-templated transcription, initiation
AL509_17320	COG0840	transmembrane signaling receptor activity
AL509_17325	COG0583	DNA-binding transcription factor activity
AL509_17335	COG0735	belongs to the Fur family
AL509_17355	COG2818	Glycosylase
AL509_17360	COG1368	sulfuric ester hydrolase activity
AL509_17365	COG2982	Protein involved in outer membrane biogenesis
AL509_17380	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_17410	COG2154	pterin-4-alpha-carbinolamine dehydratase
AL509_17440	COG3178	'Phosphotransferase
AL509_17445	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AL509_17450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL509_17455	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AL509_17460	COG1929	Belongs to the glycerate kinase type-1 family
AL509_17465	COG0469	pyruvate kinase activity
AL509_17470	COG0700	Nucleoside recognition
AL509_17475	COG1960	acyl-CoA dehydrogenase activity
AL509_17480	COG0242	peptide deformylase activity
AL509_17500	COG0204	Acyl-transferase
AL509_17505	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AL509_17510	COG0751	glycine-tRNA ligase activity
AL509_17515	COG0752	glycyl-tRNA synthetase alpha subunit
AL509_17520	COG1024	Enoyl-CoA hydratase
AL509_17545	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL509_17550	COG2030	dehydratase
AL509_17555	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_17570	COG2070	2-Nitropropane dioxygenase
AL509_17580	COG0318	PFAM AMP-dependent synthetase and ligase
AL509_17585	COG0183	Belongs to the thiolase family
AL509_17595	COG1960	acyl-CoA dehydrogenase activity
AL509_17605	COG1024	Enoyl-CoA hydratase
AL509_17615	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
AL509_17625	COG2301	Belongs to the HpcH HpaI aldolase family
AL509_17630	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL509_17640	COG0617	tRNA 3'-terminal CCA addition
AL509_17655	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AL509_17665	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AL509_17670	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AL509_17675	COG0586	Pfam SNARE associated Golgi protein
AL509_17685	COG0860	N-Acetylmuramoyl-L-alanine amidase
AL509_17690	COG0114	fumarate hydratase activity
AL509_17700	COG3181	Tripartite tricarboxylate transporter family receptor
AL509_17715	COG0531	amino acid
AL509_17720	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL509_17725	COG1960	acyl-CoA dehydrogenase activity
AL509_17730	COG0583	DNA-binding transcription factor activity
AL509_17735	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL509_17765	COG0583	DNA-binding transcription factor activity
AL509_17775	COG0579	oxidoreductase
AL509_17785	COG0259	pyridoxamine-phosphate oxidase activity
AL509_17800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL509_17805	COG0577	efflux transmembrane transporter activity
AL509_17805	COG1136	(ABC) transporter
AL509_17810	COG1538	Outer membrane efflux protein
AL509_17815	COG0583	DNA-binding transcription factor activity
AL509_17830	COG0577	efflux transmembrane transporter activity
AL509_17830	COG1136	(ABC) transporter
AL509_17850	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AL509_17885	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AL509_17895	COG0800	Aldolase
AL509_17910	COG1216	Glycosyl transferase, family 2
AL509_17910	COG0463	Glycosyl transferase, family 2
AL509_17915	COG0410	ABC transporter
AL509_17920	COG0411	ABC transporter
AL509_17935	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_17940	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AL509_17960	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AL509_17965	COG4638	Rieske (2fe-2S)
AL509_17990	COG0747	negative chemotaxis
AL509_18000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL509_18005	COG0444	Belongs to the ABC transporter superfamily
AL509_18010	COG4608	Belongs to the ABC transporter superfamily
AL509_18030	COG2746	aminoglycoside 3-N-acetyltransferase activity
AL509_18035	COG0488	(ABC) transporter
AL509_18055	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AL509_18060	COG2894	cell division
AL509_18065	COG0850	regulation of cytokinetic process
AL509_18070	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL509_18080	COG1294	oxidase, subunit
AL509_18085	COG0514	ATP-dependent DNA helicase (RecQ)
AL509_18095	COG0745	RESPONSE REGULATOR receiver
AL509_18100	COG4191	Histidine kinase
AL509_18105	COG2255	four-way junction helicase activity
AL509_18115	COG1090	epimerase
AL509_18120	COG0632	four-way junction helicase activity
AL509_18145	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL509_18155	COG0006	proline dipeptidase activity
AL509_18170	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AL509_18175	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL509_18190	COG4783	chaperone-mediated protein folding
AL509_18230	COG2814	Major facilitator Superfamily
AL509_18235	COG4771	TonB-dependent receptor
AL509_18245	COG0513	Belongs to the DEAD box helicase family
AL509_18260	COG1546	Belongs to the CinA family
AL509_18260	COG1058	Belongs to the CinA family
AL509_18265	COG1414	Transcriptional regulator
AL509_18280	COG0167	dihydroorotate dehydrogenase activity
AL509_18285	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AL509_18290	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AL509_18370	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AL509_18375	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL509_18380	COG0735	belongs to the Fur family
AL509_18385	COG0497	DNA recombination
AL509_18390	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AL509_18395	COG1420	regulation of RNA biosynthetic process
AL509_18400	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AL509_18410	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AL509_18420	COG0443	Heat shock 70 kDa protein
AL509_18425	COG0484	heat shock protein binding
AL509_18435	COG0612	Peptidase, M16
AL509_18460	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AL509_18500	COG0840	transmembrane signaling receptor activity
AL509_18505	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL509_18520	COG0745	RESPONSE REGULATOR receiver
AL509_18525	COG2205	protein histidine kinase activity
AL509_18530	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AL509_18535	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AL509_18555	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL509_18565	COG1193	negative regulation of DNA recombination
AL509_18570	COG0492	ferredoxin-NADP+ reductase activity
AL509_18575	COG1674	ftsk spoiiie
AL509_18580	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AL509_18585	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AL509_18590	COG0517	IMP dehydrogenase activity
AL509_18590	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AL509_18610	COG0601	transmembrane transport
AL509_18625	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL509_18630	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AL509_18635	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AL509_18665	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL509_18675	COG4774	siderophore transport
AL509_18680	COG4607	ABC-type enterochelin transport system periplasmic component
AL509_18685	COG4604	ABC transporter, ATP-binding protein
AL509_18690	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL509_18720	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_18725	COG3022	response to hydroperoxide
AL509_18735	COG1289	transmembrane transporter activity
AL509_18740	COG0028	Belongs to the TPP enzyme family
AL509_18745	COG0440	acetolactate synthase activity
AL509_18750	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AL509_18755	COG1183	phosphatidylcholine synthase activity
AL509_18765	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AL509_18770	COG1185	polyribonucleotide nucleotidyltransferase activity
AL509_18780	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AL509_18790	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL509_18800	COG2207	Transcriptional regulator
AL509_18805	COG2814	Major facilitator Superfamily
AL509_18830	COG0149	triose-phosphate isomerase activity
AL509_18835	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AL509_18850	COG3047	cAMP biosynthetic process
AL509_18850	COG2885	chlorophyll binding
AL509_18905	COG1910	domain protein
AL509_18940	COG1116	anion transmembrane transporter activity
AL509_18955	COG1595	DNA-templated transcription, initiation
AL509_18960	COG3712	iron ion homeostasis
AL509_18985	COG0642	Histidine kinase
AL509_18995	COG2851	Citrate transporter
AL509_19000	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_19010	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AL509_19015	COG3706	GGDEF domain
AL509_19015	COG0745	RESPONSE REGULATOR receiver
AL509_19020	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AL509_19025	COG4191	Histidine kinase
AL509_19025	COG0784	Response regulator, receiver
AL509_19035	COG3604	Transcriptional regulator
AL509_19040	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
AL509_19045	COG3813	Protein conserved in bacteria
AL509_19050	COG2354	Protein conserved in bacteria
AL509_19055	COG4772	TonB-dependent receptor
AL509_19060	COG1522	sequence-specific DNA binding
AL509_19090	COG0747	negative chemotaxis
AL509_19130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL509_19135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL509_19145	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL509_19150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL509_19155	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL509_19175	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL509_19185	COG1309	transcriptional regulator
AL509_19190	COG0583	DNA-binding transcription factor activity
AL509_19210	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AL509_19235	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL509_19240	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL509_19245	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL509_19250	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL509_19255	COG0649	NAD binding
AL509_19260	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AL509_19270	COG1034	ATP synthesis coupled electron transport
AL509_19275	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AL509_19280	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL509_19290	COG0713	ATP synthesis coupled electron transport
AL509_19305	COG1007	ATP synthesis coupled electron transport
AL509_19315	COG4774	siderophore transport
AL509_19320	COG4774	siderophore transport
AL509_19325	COG0560	Phosphoserine phosphatase
AL509_19330	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AL509_19335	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AL509_19340	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AL509_19350	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL509_19355	COG0450	alkyl hydroperoxide reductase
AL509_19360	COG2205	protein histidine kinase activity
AL509_19365	COG0745	RESPONSE REGULATOR receiver
AL509_19370	COG1214	PFAM Peptidase M22, glycoprotease
AL509_19375	COG1573	uracil-dna glycosylase
AL509_19380	COG0477	Major facilitator Superfamily
AL509_19385	COG1196	nuclear chromosome segregation
AL509_19395	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AL509_19400	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL509_19410	COG2917	probably involved in intracellular septation
AL509_19415	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL509_19420	COG1122	ATPase activity
AL509_19425	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AL509_19430	COG1268	BioY protein
AL509_19470	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AL509_19500	COG0411	ABC transporter
AL509_19505	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AL509_19525	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AL509_19530	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AL509_19535	COG0251	oxidation-reduction process
AL509_19545	COG3228	Belongs to the MtfA family
AL509_19550	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL509_19560	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL509_19565	COG0133	tryptophan synthase activity
AL509_19570	COG0159	tryptophan synthase activity
AL509_19575	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AL509_19580	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AL509_19585	COG1530	ribonuclease E activity
AL509_19595	COG0546	phosphoglycolate phosphatase activity
AL509_19600	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AL509_19605	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AL509_19620	COG0424	maF-like protein
AL509_19625	COG1399	metal-binding, possibly nucleic acid-binding protein
AL509_19630	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AL509_19635	COG0416	fatty acid biosynthetic process
AL509_19640	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL509_19645	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AL509_19655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL509_19660	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL509_19685	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL509_19690	COG0481	GTPase activity
AL509_19695	COG0681	Belongs to the peptidase S26 family
AL509_19700	COG0571	ribonuclease III activity
AL509_19705	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AL509_19710	COG1381	Involved in DNA repair and RecF pathway recombination
AL509_19755	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AL509_19780	COG0583	DNA-binding transcription factor activity
AL509_19790	COG0791	NLP P60 protein
AL509_19800	COG3193	protein, possibly involved in utilization of glycolate and propanediol
AL509_19815	COG0697	spore germination
AL509_19820	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AL509_19845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL509_19870	COG2153	protein acetylation
AL509_19880	COG1446	asparaginase
AL509_19885	COG4172	Belongs to the ABC transporter superfamily
AL509_19890	COG0747	negative chemotaxis
AL509_19925	COG0504	CTP synthase activity
AL509_19935	COG0148	phosphopyruvate hydratase activity
AL509_19945	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AL509_19955	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL509_20010	COG0039	L-malate dehydrogenase activity
AL509_20015	COG2188	Transcriptional regulator
AL509_20020	COG2009	succinate dehydrogenase
AL509_20025	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AL509_20030	COG1053	succinate dehydrogenase
AL509_20035	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AL509_20040	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AL509_20045	COG0372	Belongs to the citrate synthase family
AL509_20060	COG0280	phosphate acetyltransferase
AL509_20060	COG0281	malic enzyme
AL509_20070	COG1297	OPT oligopeptide transporter protein
AL509_20075	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL509_20090	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AL509_20095	COG1522	sequence-specific DNA binding
AL509_20100	COG0567	Dehydrogenase, E1 component
AL509_20110	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL509_20115	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AL509_20120	COG1595	DNA-templated transcription, initiation
AL509_20125	COG3712	iron ion homeostasis
AL509_20130	COG4774	siderophore transport
AL509_20155	COG0180	Tryptophanyl-tRNA synthetase
AL509_20165	COG2183	response to ionizing radiation
AL509_20170	COG1199	ATP-dependent helicase activity
AL509_20180	COG0564	pseudouridine synthase activity
AL509_20190	COG3243	poly(R)-hydroxyalkanoic acid synthase
AL509_20195	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_20200	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
AL509_20225	COG2831	hemolysin activation secretion protein
AL509_20265	COG2823	Periplasmic or secreted lipoprotein
AL509_20270	COG3237	CsbD-like
AL509_20275	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AL509_20275	COG0189	ligase activity
AL509_20280	COG0189	ligase activity
AL509_20280	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AL509_20285	COG1132	(ABC) transporter
AL509_20300	COG2833	Protein of unknown function (DUF455)
AL509_20305	COG2258	MOSC domain
AL509_20310	COG2951	lytic endotransglycosylase activity
AL509_20325	COG1960	acyl-CoA dehydrogenase activity
AL509_20335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AL509_20345	COG1696	Membrane protein involved in D-alanine export
AL509_20365	COG1215	transferase activity, transferring glycosyl groups
AL509_20375	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AL509_20400	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL509_20415	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AL509_20425	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AL509_20435	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AL509_20440	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AL509_20460	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AL509_20465	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AL509_20475	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL509_20500	COG2951	lytic endotransglycosylase activity
AL509_20505	COG0123	including yeast histone deacetylase and acetoin utilization protein
AL509_20530	COG2985	domain, Protein
AL509_20535	COG1960	acyl-CoA dehydrogenase activity
AL509_20540	COG0450	alkyl hydroperoxide reductase
AL509_20550	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AL509_20555	COG4208	sulfate ABC transporter
AL509_20560	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AL509_20565	COG0175	sulfate reduction
AL509_20595	COG0335	large ribosomal subunit rRNA binding
AL509_20605	COG1162	GTPase activity
AL509_20610	COG0501	Belongs to the peptidase M48B family
AL509_20615	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AL509_20620	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AL509_20625	COG3327	negative regulation of DNA-templated transcription, initiation
AL509_20630	COG3396	Phenylacetate-CoA oxygenase
AL509_20635	COG3460	Phenylacetate-CoA oxygenase
AL509_20640	COG2151	metal-sulfur cluster biosynthetic enzyme
AL509_20645	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL509_20650	COG1012	belongs to the aldehyde dehydrogenase family
AL509_20655	COG1024	Enoyl-CoA hydratase
AL509_20665	COG0534	Mate efflux family protein
AL509_20690	COG0254	rRNA binding
AL509_20695	COG3483	tryptophan 2,3-dioxygenase activity
AL509_20700	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AL509_20705	COG2003	Belongs to the UPF0758 family
AL509_20720	COG0625	glutathione transferase activity
AL509_20725	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL509_20730	COG0642	Histidine kinase
AL509_20735	COG0745	RESPONSE REGULATOR receiver
AL509_20750	COG0523	cobalamin synthesis protein
AL509_20755	COG0523	cobalamin synthesis protein
AL509_20760	COG0583	DNA-binding transcription factor activity
AL509_20770	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AL509_20775	COG1187	pseudouridine synthase activity
AL509_20780	COG0779	Required for maturation of 30S ribosomal subunits
AL509_20785	COG2251	uridine kinase activity
AL509_20785	COG0195	Participates in both transcription termination and antitermination
AL509_20790	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AL509_20795	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AL509_20800	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AL509_20825	COG3181	Tripartite tricarboxylate transporter family receptor
AL509_20830	COG1473	amidohydrolase
AL509_20835	COG1611	Belongs to the LOG family
AL509_20850	COG0412	Dienelactone hydrolase
AL509_20855	COG1283	sodium-dependent phosphate transmembrane transporter activity
AL509_20860	COG1760	l-serine dehydratase
AL509_20865	COG0501	Belongs to the peptidase M48B family
AL509_20885	COG0583	DNA-binding transcription factor activity
AL509_20890	COG3842	ATPase activity
AL509_20900	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL509_20905	COG1840	ABC-type Fe3 transport system, periplasmic component
AL509_20925	COG3181	Tripartite tricarboxylate transporter family receptor
AL509_20935	COG0142	geranyltranstransferase activity
AL509_20940	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AL509_20945	COG1469	GTP cyclohydrolase I activity
AL509_20950	COG3739	integral membrane protein
AL509_20955	COG0360	Binds together with S18 to 16S ribosomal RNA
AL509_20960	COG2965	DNA replication, synthesis of RNA primer
AL509_20965	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AL509_20970	COG0359	binds to the 23S rRNA
AL509_20980	COG0305	Participates in initiation and elongation during chromosome replication
AL509_20990	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AL509_21025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL509_21070	COG0540	Belongs to the ATCase OTCase family
AL509_21095	COG0642	Histidine kinase
AL509_21105	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AL509_21110	COG2137	regulation of response to DNA damage stimulus
AL509_21115	COG0583	DNA-binding transcription factor activity
AL509_21120	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AL509_21135	COG0045	succinate-CoA ligase (ADP-forming) activity
AL509_21140	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AL509_21145	COG0861	Integral membrane protein TerC family
AL509_21150	COG0861	Integral membrane protein TerC family
AL509_21155	COG0181	hydroxymethylbilane synthase activity
AL509_21175	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AL509_21185	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_21200	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_21205	COG0411	ABC transporter
AL509_21215	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL509_21235	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AL509_21240	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AL509_21250	COG0436	Aminotransferase
AL509_21270	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AL509_21275	COG0308	aminopeptidase N
AL509_21285	COG0312	modulator of DNA gyrase
AL509_21290	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL509_21295	COG0277	FAD linked oxidase domain protein
AL509_21300	COG0277	FAD linked oxidase domain protein
AL509_21305	COG0277	FAD linked oxidase domain protein
AL509_21310	COG0247	lactate metabolic process
AL509_21315	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AL509_21320	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AL509_21325	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AL509_21340	COG0583	DNA-binding transcription factor activity
AL509_21345	COG0482	sulfurtransferase activity
AL509_21350	COG0730	response to heat
AL509_21355	COG0625	glutathione transferase activity
AL509_21365	COG3909	cytochrome
AL509_21405	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AL509_21530	COG0697	spore germination
AL509_21585	COG0419	ATPase involved in DNA repair
AL509_21590	COG2974	May be involved in recombination
AL509_21895	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
AL509_21905	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL509_21910	COG0069	glutamate synthase activity
AL509_21915	COG2391	methyltransferase activity
AL509_21920	COG0679	Auxin Efflux Carrier
AL509_21930	COG2153	protein acetylation
AL509_21950	COG0557	exoribonuclease II activity
AL509_21955	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL509_21965	COG3128	pkhd-type hydroxylase
AL509_21970	COG0776	regulation of translation
AL509_21995	COG0745	RESPONSE REGULATOR receiver
AL509_22000	COG0642	Histidine kinase
AL509_22005	COG3158	transport of potassium into the cell
AL509_22015	COG0137	argininosuccinate synthase activity
AL509_22020	COG0583	DNA-binding transcription factor activity
AL509_22025	COG3618	amidohydrolase
AL509_22050	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AL509_22055	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AL509_22075	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL509_22080	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AL509_22090	COG3642	lipopolysaccharide core region biosynthetic process
AL509_22100	COG3842	ATPase activity
AL509_22105	COG1176	ABC-type spermidine putrescine transport system, permease component I
AL509_22110	COG1177	transmembrane transport
AL509_22130	COG1322	Protein conserved in bacteria
AL509_22140	COG1960	acyl-CoA dehydrogenase activity
AL509_22150	COG0704	Plays a role in the regulation of phosphate uptake
AL509_22160	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AL509_22165	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AL509_22165	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AL509_22170	COG1643	Atp-dependent helicase
AL509_22175	COG0395	ABC-type sugar transport system, permease component
AL509_22180	COG1116	anion transmembrane transporter activity
AL509_22195	COG0438	transferase activity, transferring glycosyl groups
AL509_22200	COG0726	polysaccharide deacetylase
AL509_22215	COG0726	polysaccharide deacetylase
AL509_22240	COG1132	(ABC) transporter
AL509_22245	COG0475	glutathione-regulated potassium exporter activity
AL509_22245	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AL509_22250	COG5001	Diguanylate cyclase
AL509_22250	COG4251	negative regulation of phosphorylation
AL509_22250	COG3706	GGDEF domain
AL509_22250	COG2203	Gaf domain
AL509_22260	COG1530	ribonuclease E activity
AL509_22290	COG2204	response regulator
AL509_22295	COG4191	Histidine kinase
AL509_22300	COG1301	dicarboxylic acid transport
AL509_22305	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AL509_22310	COG0799	negative regulation of ribosome biogenesis
AL509_22315	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AL509_22320	COG0408	coproporphyrinogen oxidase activity
AL509_22325	COG0151	Belongs to the GarS family
AL509_22330	COG0217	transcriptional regulatory protein
AL509_22335	COG0433	COG0433 Predicted ATPase
AL509_22340	COG0473	3-isopropylmalate dehydrogenase activity
AL509_22350	COG2814	Major facilitator Superfamily
AL509_22355	COG1566	PFAM secretion protein HlyD family protein
AL509_22365	COG1846	Transcriptional regulator
AL509_22395	COG3391	amine dehydrogenase activity
AL509_22405	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AL509_22425	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AL509_22430	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AL509_22440	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AL509_22450	COG0187	DNA topoisomerase II activity
AL509_22470	COG2311	Membrane
AL509_22475	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AL509_22495	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL509_22500	COG0662	Cupin 2, conserved barrel domain protein
AL509_22505	COG5285	phytanoyl-CoA dioxygenase
AL509_22510	COG0633	Ferredoxin
AL509_22510	COG3217	Mosc domain protein beta barrel domain protein
AL509_22515	COG2076	Multidrug Resistance protein
AL509_22520	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AL509_22530	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL509_22545	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AL509_22550	COG0425	Belongs to the sulfur carrier protein TusA family
AL509_22560	COG0228	four-way junction DNA binding
AL509_22565	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AL509_22570	COG0336	Belongs to the RNA methyltransferase TrmD family
AL509_22575	COG1396	sequence-specific DNA binding
AL509_22580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL509_22585	COG0765	amino acid transport
AL509_22595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL509_22600	COG0525	valine-tRNA ligase activity
AL509_22605	COG0105	UTP biosynthetic process
AL509_22610	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AL509_22620	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AL509_22625	COG0124	histidyl-tRNA synthetase
AL509_22630	COG2976	Protein conserved in bacteria
AL509_22635	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL509_22640	COG1160	GTP binding
AL509_22645	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AL509_22650	COG1923	regulation of RNA biosynthetic process
AL509_22655	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AL509_22660	COG0330	HflC and HflK could
AL509_22665	COG0330	HflC and HflK could
AL509_22670	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AL509_22675	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AL509_22680	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AL509_22685	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AL509_22705	COG0438	transferase activity, transferring glycosyl groups
AL509_22745	COG4964	Belongs to the GSP D family
AL509_22775	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AL509_22785	COG1295	ribonuclease BN
AL509_22795	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AL509_22820	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AL509_22825	COG4783	chaperone-mediated protein folding
AL509_22860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL509_22865	COG2274	protein secretion by the type I secretion system
AL509_22875	COG1538	Outer membrane efflux protein
AL509_22880	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AL509_22885	COG0066	3-isopropylmalate dehydratase activity
AL509_22890	COG0473	3-isopropylmalate dehydrogenase activity
AL509_22895	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AL509_22905	COG0101	tRNA pseudouridine synthase activity
AL509_22910	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AL509_22925	COG0596	Alpha beta hydrolase
AL509_22960	COG0129	dihydroxy-acid dehydratase activity
AL509_22965	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL509_22970	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL509_22975	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AL509_22980	COG1609	Transcriptional regulator
AL509_23000	COG4172	Belongs to the ABC transporter superfamily
AL509_23005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL509_23010	COG0601	transmembrane transport
AL509_23020	COG1012	belongs to the aldehyde dehydrogenase family
AL509_23050	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AL509_23055	COG2197	response regulator
AL509_23065	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AL509_23070	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AL509_23075	COG0189	ligase activity
AL509_23085	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL509_23090	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AL509_23095	COG0004	ammonium transporteR
AL509_23100	COG0347	Belongs to the P(II) protein family
AL509_23110	COG2960	long-chain fatty acid transporting porin activity
AL509_23120	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AL509_23125	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AL509_23130	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AL509_23135	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL509_23135	COG0072	phenylalanine-tRNA ligase activity
AL509_23185	COG0384	phenazine biosynthesis protein PhzF
AL509_23190	COG0456	acetyltransferase
AL509_23225	COG1522	sequence-specific DNA binding
AL509_23255	COG0583	DNA-binding transcription factor activity
AL509_23260	COG3181	Tripartite tricarboxylate transporter family receptor
AL509_23285	COG1116	anion transmembrane transporter activity
AL509_23315	COG5265	(ABC) transporter
AL509_23320	COG0656	L-ascorbic acid biosynthetic process
AL509_23335	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AL509_23345	COG1917	Cupin 2, conserved barrel domain protein
AL509_23345	COG4977	sequence-specific DNA binding
AL509_23350	COG2223	nitrite transmembrane transporter activity
AL509_23360	COG1215	transferase activity, transferring glycosyl groups
AL509_23365	COG0726	polysaccharide deacetylase
AL509_23365	COG1649	PFAM Uncharacterised BCR, COG1649
AL509_23370	COG0457	Tetratricopeptide repeat
AL509_23375	COG3706	GGDEF domain
AL509_23400	COG1610	YqeY-like protein
AL509_23405	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL509_23410	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_23450	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AL509_23460	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL509_23465	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL509_23485	COG1017	nitric oxide dioxygenase activity
AL509_23485	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL509_23490	COG1959	2 iron, 2 sulfur cluster binding
AL509_23495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL509_23500	COG0697	spore germination
AL509_23505	COG0506	proline dehydrogenase activity
AL509_23525	COG0583	DNA-binding transcription factor activity
AL509_23535	COG0625	glutathione transferase activity
AL509_23550	COG2814	Major facilitator Superfamily
AL509_23570	COG1960	acyl-CoA dehydrogenase activity
AL509_23575	COG0318	PFAM AMP-dependent synthetase and ligase
AL509_23615	COG3245	cytochrome
AL509_23620	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AL509_23635	COG1280	lysine exporter protein (LysE YggA)
AL509_23650	COG0697	spore germination
AL509_23655	COG0697	spore germination
AL509_23670	COG0534	Mate efflux family protein
AL509_23675	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AL509_23680	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_23690	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL509_23695	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AL509_23710	COG3119	arylsulfatase activity
AL509_23720	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_23745	COG0583	DNA-binding transcription factor activity
AL509_23750	COG0243	molybdopterin cofactor binding
AL509_23755	COG3781	membrane
AL509_23760	COG2207	Transcriptional regulator
AL509_23765	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_23770	COG3181	Tripartite tricarboxylate transporter family receptor
AL509_23775	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL509_23780	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AL509_23790	COG1304	FMN binding
AL509_23825	COG3088	subunit of a heme lyase
AL509_23835	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AL509_23855	COG4133	protoheme IX ABC transporter activity
AL509_23870	COG3381	protein complex oligomerization
AL509_23890	COG4235	cytochrome complex assembly
AL509_23900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL509_23910	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AL509_23930	COG3005	denitrification pathway
AL509_23935	COG3043	anaerobic respiration
AL509_23950	COG3246	L-lysine catabolic process to acetate
AL509_23955	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL509_23960	COG0583	DNA-binding transcription factor activity
AL509_23970	COG0129	dihydroxy-acid dehydratase activity
AL509_23975	COG3181	Tripartite tricarboxylate transporter family receptor
AL509_23980	COG5001	Diguanylate cyclase
AL509_23985	COG1024	Enoyl-CoA hydratase
AL509_24010	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL509_24020	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
AL509_24025	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_24030	COG0583	DNA-binding transcription factor activity
AL509_24035	COG2610	gluconate transmembrane transporter activity
AL509_24075	COG0235	Class ii aldolase
AL509_24080	COG0477	Major facilitator Superfamily
AL509_24100	COG0318	PFAM AMP-dependent synthetase and ligase
AL509_24140	COG1280	lysine exporter protein (LysE YggA)
AL509_24145	COG5265	(ABC) transporter
AL509_24155	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL509_24170	COG0318	PFAM AMP-dependent synthetase and ligase
AL509_24175	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_24210	COG0583	DNA-binding transcription factor activity
AL509_24220	COG0583	DNA-binding transcription factor activity
AL509_24230	COG0583	DNA-binding transcription factor activity
AL509_24260	COG2226	methyltransferase
AL509_24270	COG2814	Major facilitator Superfamily
AL509_24340	COG2070	2-Nitropropane dioxygenase
AL509_24380	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_24385	COG2186	Transcriptional regulator
AL509_24390	COG1012	belongs to the aldehyde dehydrogenase family
AL509_24395	COG0307	riboflavin synthase, alpha
AL509_24405	COG2271	Major facilitator Superfamily
AL509_24415	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL509_24425	COG0789	Transcriptional regulator
AL509_24450	COG4774	siderophore transport
AL509_24460	COG0022	dehydrogenase e1 component
AL509_24480	COG1598	PFAM Uncharacterised protein family UPF0150
AL509_24485	COG0165	Argininosuccinate lyase
AL509_24490	COG0668	transmembrane transport
AL509_24560	COG2165	general secretion pathway protein
AL509_24595	COG0583	DNA-binding transcription factor activity
AL509_24605	COG0747	negative chemotaxis
AL509_24610	COG0601	transmembrane transport
AL509_24620	COG4172	Belongs to the ABC transporter superfamily
AL509_24625	COG4681	YaeQ
AL509_24640	COG0477	Major facilitator Superfamily
AL509_24645	COG3161	chorismate lyase activity
AL509_24650	COG1187	pseudouridine synthase activity
AL509_24655	COG0583	DNA-binding transcription factor activity
AL509_24670	COG1538	Outer membrane efflux protein
AL509_24680	COG1999	signal sequence binding
AL509_24690	COG0339	signal peptide processing
AL509_24700	COG4566	intracellular signal transduction
AL509_24710	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AL509_24720	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL509_24730	COG0583	DNA-binding transcription factor activity
AL509_24750	COG4797	methyltransferase
AL509_24750	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL509_24755	COG1191	sigma factor activity
AL509_24775	COG1360	Flagellar Motor Protein
AL509_24790	COG0835	chemotaxis
AL509_24795	COG0840	transmembrane signaling receptor activity
AL509_24800	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AL509_24805	COG2201	protein-glutamate methylesterase activity
AL509_24810	COG0745	RESPONSE REGULATOR receiver
AL509_24815	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AL509_24820	COG0840	transmembrane signaling receptor activity
AL509_24845	COG2747	anti-sigma28 factor FlgM
AL509_24855	COG1815	bacterial-type flagellum-dependent cell motility
AL509_24860	COG1558	bacterial-type flagellum-dependent cell motility
AL509_24865	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AL509_24870	COG1749	Flagellar hook protein flgE
AL509_24875	COG4787	bacterial-type flagellum-dependent cell motility
AL509_24880	COG4786	Flagellar basal body rod
AL509_24885	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AL509_24890	COG1706	bacterial-type flagellum-dependent cell motility
AL509_24900	COG1256	bacterial-type flagellum assembly
AL509_24910	COG0840	transmembrane signaling receptor activity
AL509_24925	COG0840	transmembrane signaling receptor activity
AL509_24930	COG0840	transmembrane signaling receptor activity
AL509_24950	COG3190	flagellar
AL509_24965	COG1580	Controls the rotational direction of flagella during chemotaxis
AL509_24990	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AL509_24995	COG1766	The M ring may be actively involved in energy transduction
AL509_25000	COG1677	Flagellar hook-basal body complex protein FliE
AL509_25010	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AL509_25035	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AL509_25040	COG1334	flagellar protein FlaG
AL509_25045	COG1414	Transcriptional regulator
AL509_25055	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL509_25060	COG3181	Tripartite tricarboxylate transporter family receptor
AL509_25070	COG0285	dihydrofolate synthase activity
AL509_25090	COG1451	nucleotide metabolic process
AL509_25095	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AL509_25105	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AL509_25110	COG0024	Methionine aminopeptidase
AL509_25115	COG0052	Belongs to the universal ribosomal protein uS2 family
AL509_25120	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AL509_25125	COG0528	UMP kinase activity
AL509_25130	COG0233	cytoplasmic translational termination
AL509_25135	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AL509_25145	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AL509_25150	COG0750	zinc metalloprotease
AL509_25155	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL509_25160	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AL509_25165	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL509_25170	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AL509_25180	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL509_25185	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AL509_25190	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL509_25200	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AL509_25220	COG0519	Catalyzes the synthesis of GMP from XMP
AL509_25220	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AL509_25235	COG3706	GGDEF domain
AL509_25235	COG0745	RESPONSE REGULATOR receiver
AL509_25240	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AL509_25245	COG2867	negative regulation of translational initiation
AL509_25265	COG1024	Enoyl-CoA hydratase
AL509_25265	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL509_25290	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AL509_25295	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AL509_25300	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AL509_25305	COG0084	hydrolase, TatD family'
AL509_25320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL509_25330	COG1126	abc transporter atp-binding protein
AL509_25345	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AL509_25355	COG0095	Lipoate-protein ligase
AL509_25370	COG0625	glutathione transferase activity
AL509_25380	COG1522	sequence-specific DNA binding
AL509_25385	COG0386	Belongs to the glutathione peroxidase family
AL509_25390	COG2814	Major facilitator Superfamily
AL509_25415	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AL509_25425	COG0840	transmembrane signaling receptor activity
AL509_25435	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL509_25465	COG1902	pentaerythritol trinitrate reductase activity
AL509_25495	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AL509_25510	COG0842	Transport permease protein
AL509_25515	COG1131	(ABC) transporter
AL509_25530	COG2130	NADP-dependent
AL509_25555	COG3842	ATPase activity
AL509_25560	COG3842	ATPase activity
AL509_25570	COG0395	ABC-type sugar transport system, permease component
AL509_25620	COG0346	lactoylglutathione lyase activity
AL509_25625	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL509_25645	COG3634	alkyl hydroperoxide reductase activity
AL509_25650	COG1959	2 iron, 2 sulfur cluster binding
AL509_25655	COG1960	acyl-CoA dehydrogenase activity
AL509_25695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL509_25700	COG0420	3'-5' exonuclease activity
AL509_25730	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AL509_25730	COG2111	Na H antiporter
AL509_25735	COG1006	Multisubunit Na H antiporter MnhC subunit
AL509_25740	COG0651	ATP synthesis coupled electron transport
AL509_25745	COG1863	multisubunit Na H antiporter MnhE subunit
AL509_25750	COG2212	antiporter activity
AL509_25755	COG1320	monovalent cation:proton antiporter activity
AL509_25765	COG0590	tRNA wobble adenosine to inosine editing
AL509_25770	COG1619	proteins homologs of microcin C7 resistance protein MccF
AL509_25775	COG0488	(ABC) transporter
AL509_25780	COG2814	Major facilitator Superfamily
AL509_25810	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL509_25815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL509_25825	COG2252	PERMEase
AL509_25830	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AL509_25835	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AL509_25840	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AL509_25845	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AL509_25870	COG0583	DNA-binding transcription factor activity
AL509_25875	COG2814	Major facilitator Superfamily
AL509_25880	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AL509_25885	COG0789	Transcriptional regulator
AL509_25900	COG0678	peroxiredoxin activity
AL509_25900	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AL509_25915	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AL509_25920	COG0584	glycerophosphoryl diester phosphodiesterase
AL509_25930	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL509_25940	COG4181	ATPase activity
AL509_25950	COG1178	ABC-type Fe3 transport system permease component
AL509_25955	COG3842	ATPase activity
AL509_25960	COG0583	DNA-binding transcription factor activity
AL509_25965	COG0560	Phosphoserine phosphatase
AL509_25980	COG0583	DNA-binding transcription factor activity
AL509_25995	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL509_26010	COG0583	DNA-binding transcription factor activity
AL509_26015	COG4336	lyase activity
AL509_26025	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL509_26040	COG0411	ABC transporter
AL509_26050	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL509_26070	COG2816	NAD+ diphosphatase activity
AL509_26090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL509_26095	COG0765	amino acid transport
AL509_26100	COG1126	abc transporter atp-binding protein
AL509_26105	COG1335	isochorismatase
AL509_26115	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL509_26120	COG1758	RNA polymerase activity
AL509_26125	COG0194	GDP metabolic process
AL509_26130	COG3258	Cytochrome c
AL509_26135	COG2863	cytochrome
AL509_26140	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_26145	COG0791	NLP P60 protein
AL509_26160	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AL509_26165	COG0833	amino acid
AL509_26170	COG1561	YicC-like family, N-terminal region
AL509_26175	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AL509_26185	COG1960	acyl-CoA dehydrogenase activity
AL509_26195	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AL509_26200	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AL509_26210	COG3852	Histidine kinase
AL509_26215	COG2204	response regulator
AL509_26220	COG0583	DNA-binding transcription factor activity
AL509_26225	COG1741	Belongs to the pirin family
AL509_26230	COG1741	Belongs to the pirin family
AL509_26235	COG1690	Belongs to the RtcB family
AL509_26240	COG3181	Tripartite tricarboxylate transporter family receptor
AL509_26245	COG3842	ATPase activity
AL509_26250	COG4149	molybdate abc transporter
AL509_26255	COG1840	ABC-type Fe3 transport system, periplasmic component
AL509_26265	COG3181	Tripartite tricarboxylate transporter family receptor
AL509_26280	COG0583	DNA-binding transcription factor activity
AL509_26290	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AL509_26300	COG0783	Belongs to the Dps family
AL509_26310	COG0457	Tetratricopeptide repeat
AL509_26315	COG0438	transferase activity, transferring glycosyl groups
AL509_26340	COG1560	Kdo2-lipid A biosynthetic process
AL509_26340	COG4783	chaperone-mediated protein folding
AL509_26345	COG3866	Pectate lyase
AL509_26360	COG0745	RESPONSE REGULATOR receiver
AL509_26365	COG2205	protein histidine kinase activity
AL509_26380	COG3842	ATPase activity
AL509_26385	COG0395	ABC-type sugar transport system, permease component
AL509_26390	COG1175	transmembrane transport
AL509_26395	COG1653	transport
AL509_26405	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AL509_26415	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL509_26430	COG0410	ABC transporter
AL509_26440	COG1794	racemase activity, acting on amino acids and derivatives
AL509_26445	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AL509_26465	COG0625	glutathione transferase activity
AL509_26470	COG2133	pyrroloquinoline quinone binding
AL509_26480	COG0697	spore germination
AL509_26485	COG2363	Small membrane protein
AL509_26505	COG0010	Belongs to the arginase family
AL509_26510	COG1464	Belongs to the NlpA lipoprotein family
AL509_26515	COG0745	RESPONSE REGULATOR receiver
AL509_26515	COG3706	GGDEF domain
AL509_26520	COG2814	Major facilitator Superfamily
AL509_26530	COG1408	metallophosphoesterase
AL509_26540	COG0688	phosphatidylethanolamine metabolic process
AL509_26545	COG0488	(ABC) transporter
AL509_26570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL509_26575	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL509_26580	COG3300	MHYT domain
AL509_26580	COG5001	Diguanylate cyclase
AL509_26595	COG2814	Major facilitator Superfamily
AL509_26620	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AL509_26625	COG2204	response regulator
AL509_26655	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_26675	COG0693	protein deglycase activity
AL509_26725	COG3706	GGDEF domain
AL509_26730	COG0789	Transcriptional regulator
AL509_26740	COG3706	GGDEF domain
AL509_26765	COG1116	anion transmembrane transporter activity
AL509_26770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL509_26775	COG4521	taurine ABC transporter
AL509_26815	COG0628	permease
AL509_26825	COG1619	proteins homologs of microcin C7 resistance protein MccF
AL509_26840	COG0531	amino acid
AL509_26850	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AL509_26855	COG4608	Belongs to the ABC transporter superfamily
AL509_26860	COG0444	Belongs to the ABC transporter superfamily
AL509_26870	COG0601	transmembrane transport
AL509_26875	COG0747	negative chemotaxis
AL509_26885	COG0251	oxidation-reduction process
AL509_26905	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL509_26920	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AL509_26935	COG0446	pyridine nucleotide-disulphide oxidoreductase
AL509_26945	COG3971	2-oxopent-4-enoate hydratase activity
AL509_26975	COG0625	glutathione transferase activity
AL509_26990	COG0477	Major facilitator Superfamily
AL509_27015	COG0625	glutathione transferase activity
AL509_27030	COG0431	NADPH-dependent FMN reductase
AL509_27040	COG0798	PFAM Bile acid sodium symporter
AL509_27050	COG0640	Transcriptional regulator
AL509_27085	COG0583	DNA-binding transcription factor activity
AL509_27090	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AL509_27100	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL509_27105	COG1045	serine acetyltransferase
AL509_27115	COG2957	Belongs to the agmatine deiminase family
AL509_27120	COG0583	DNA-binding transcription factor activity
AL509_27140	COG1126	abc transporter atp-binding protein
AL509_27145	COG0765	amino acid transport
AL509_27150	COG4597	amino acid ABC transporter
AL509_27155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL509_27160	COG0626	cystathionine gamma-synthase activity
AL509_27165	COG0583	DNA-binding transcription factor activity
AL509_27180	COG0444	Belongs to the ABC transporter superfamily
AL509_27190	COG0601	transmembrane transport
AL509_27195	COG0747	negative chemotaxis
AL509_27205	COG0583	DNA-binding transcription factor activity
AL509_27210	COG1335	isochorismatase
AL509_27215	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AL509_27235	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL509_27250	COG0519	Catalyzes the synthesis of GMP from XMP
AL509_27250	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AL509_27260	COG1276	copper resistance
AL509_27275	COG3181	Tripartite tricarboxylate transporter family receptor
AL509_27280	COG3386	PFAM SMP-30 Gluconolaconase
AL509_27285	COG2721	sulfolactate sulfo-lyase activity
AL509_27305	COG0745	RESPONSE REGULATOR receiver
AL509_27315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL509_27320	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
AL509_27325	COG1120	ATPase activity
AL509_27330	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AL509_27345	COG0586	Pfam SNARE associated Golgi protein
AL509_27350	COG0390	transport system, permease component
AL509_27360	COG3486	L-lysine 6-monooxygenase (NADPH) activity
AL509_27410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL509_27415	COG1120	ATPase activity
AL509_27420	COG1126	abc transporter atp-binding protein
AL509_27425	COG0765	amino acid transport
AL509_27435	COG2070	2-Nitropropane dioxygenase
AL509_27450	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL509_27475	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AL509_27480	COG0583	DNA-binding transcription factor activity
AL509_27490	COG1846	Transcriptional regulator
AL509_27500	COG4191	Histidine kinase
AL509_27505	COG4566	intracellular signal transduction
AL509_27545	COG0583	DNA-binding transcription factor activity
AL509_27575	COG0765	amino acid transport
AL509_27605	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AL509_27630	COG0251	oxidation-reduction process
AL509_27645	COG4106	trans-aconitate 2-methyltransferase activity
AL509_27670	COG4948	Mandelate Racemase Muconate Lactonizing
AL509_27680	COG1802	Transcriptional regulator
AL509_27685	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL509_27700	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AL509_27720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL509_27725	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL509_27730	COG1116	anion transmembrane transporter activity
AL509_27765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL509_27790	COG2197	response regulator
AL509_27795	COG3850	Histidine kinase
AL509_27800	COG1763	Mo-molybdopterin cofactor biosynthetic process
AL509_27805	COG0288	reversible hydration of carbon dioxide
AL509_27810	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AL509_27815	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL509_27820	COG2181	nitrate reductase activity
AL509_27825	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AL509_27830	COG1140	nitrate reductase beta subunit
AL509_27835	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AL509_27840	COG2223	nitrite transmembrane transporter activity
AL509_27870	COG0583	DNA-binding transcription factor activity
AL509_27890	COG0583	DNA-binding transcription factor activity
AL509_27900	COG3181	Tripartite tricarboxylate transporter family receptor
AL509_27925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL509_27945	COG2070	2-Nitropropane dioxygenase
AL509_27960	COG5002	protein histidine kinase activity
AL509_27965	COG0745	RESPONSE REGULATOR receiver
AL509_27970	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
AL509_27975	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AL509_27985	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL509_27990	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL509_28005	COG0783	Belongs to the Dps family
AL509_28035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL509_28040	COG0697	spore germination
AL509_28045	COG2879	small protein
AL509_28050	COG1966	Carbon starvation protein
AL509_28070	COG0697	spore germination
AL509_28075	COG0583	DNA-binding transcription factor activity
AL509_28080	COG4521	taurine ABC transporter
AL509_28085	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AL509_28090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL509_28120	COG1595	DNA-templated transcription, initiation
AL509_28125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL509_28150	COG0235	Class ii aldolase
AL509_28155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL509_28165	COG0523	cobalamin synthesis protein
AL509_28170	COG1228	amidohydrolase
AL509_28175	COG4172	Belongs to the ABC transporter superfamily
AL509_28180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL509_28185	COG0601	transmembrane transport
AL509_28190	COG0747	negative chemotaxis
AL509_28205	COG1414	Transcriptional regulator
AL509_28210	COG0513	Belongs to the DEAD box helicase family
AL509_28220	COG0720	synthase
AL509_28230	COG1289	transmembrane transporter activity
AL509_28240	COG1566	PFAM secretion protein HlyD family protein
AL509_28255	COG0028	Belongs to the TPP enzyme family
AL509_28265	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_28275	COG0400	carboxylic ester hydrolase activity
AL509_28280	COG0833	amino acid
AL509_28300	COG0587	DNA-directed DNA polymerase activity
AL509_28310	COG0789	Transcriptional regulator
AL509_28320	COG0667	Aldo Keto reductase
AL509_28330	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AL509_28370	COG0765	amino acid transport
AL509_28375	COG0765	amino acid transport
AL509_28380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL509_28390	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AL509_28435	COG0840	transmembrane signaling receptor activity
AL509_28515	COG2764	glyoxalase bleomycin resistance protein dioxygenase
AL509_28565	COG3501	Rhs element vgr protein
AL509_28585	COG2080	2 iron, 2 sulfur cluster binding
AL509_28595	COG2814	Major facilitator Superfamily
AL509_28620	COG0583	DNA-binding transcription factor activity
AL509_28625	COG1028	Short-chain dehydrogenase reductase Sdr
AL509_28640	COG4774	siderophore transport
AL509_28665	COG0745	RESPONSE REGULATOR receiver
AL509_28695	COG1278	Cold shock
AL509_28705	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL509_28705	COG3320	Male sterility
AL509_28710	COG0604	alcohol dehydrogenase
AL509_28710	COG3321	synthase
AL509_28750	COG3384	dioxygenase
AL509_28820	COG1538	Outer membrane efflux protein
AL509_28830	COG3384	dioxygenase
AL509_28835	COG0601	transmembrane transport
AL509_28875	COG4221	oxidoreductase activity
AL509_28880	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AL509_28905	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL509_28910	COG1534	Rna-binding protein
AL509_28945	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AL509_28965	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL509_28975	COG0243	molybdopterin cofactor binding
AL509_28995	COG0583	DNA-binding transcription factor activity
AL509_29010	COG0583	DNA-binding transcription factor activity
AL509_29050	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AL509_29055	COG1917	Cupin 2, conserved barrel domain protein
AL509_29070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL509_29080	COG0405	Gamma-glutamyltransferase
AL509_29105	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AL509_29110	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AL509_29115	COG0372	Belongs to the citrate synthase family
AL509_29120	COG4948	Mandelate Racemase Muconate Lactonizing
AL509_29160	COG0318	PFAM AMP-dependent synthetase and ligase
AL509_29170	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AL509_29200	COG0037	tRNA processing
AL509_29210	COG1090	epimerase
AL509_29215	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL509_29240	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AL509_29255	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AL509_29275	COG2814	Major facilitator Superfamily
AL509_29305	COG2814	Major facilitator Superfamily
AL509_29320	COG2884	Cell division ATP-binding protein ftsE
AL509_29370	COG0802	atpase or kinase
AL509_29375	COG3181	Tripartite tricarboxylate transporter family receptor
AL509_29380	COG0577	efflux transmembrane transporter activity
AL509_29380	COG1136	(ABC) transporter
AL509_29390	COG1566	PFAM secretion protein HlyD family protein
AL509_29410	COG0251	oxidation-reduction process
AL509_29425	COG4605	iron ion homeostasis
AL509_29435	COG0840	transmembrane signaling receptor activity
AL509_29455	COG0411	ABC transporter
AL509_29460	COG2878	Part of a membrane complex involved in electron transport
AL509_29485	COG3210	domain, Protein
AL509_29520	COG3396	Phenylacetate-CoA oxygenase
AL509_29525	COG2050	protein possibly involved in aromatic compounds catabolism
AL509_29535	COG1722	exodeoxyribonuclease VII activity
AL509_29660	COG2945	thiolester hydrolase activity
AL509_29660	COG0596	Alpha beta hydrolase
AL509_29675	COG0424	maF-like protein
AL509_29680	COG1309	transcriptional regulator
AL509_29685	COG2755	lipolytic protein G-D-S-L family
AL509_29685	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AL509_29735	COG0776	regulation of translation
AL509_29745	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AL509_29755	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL509_29785	COG0154	amidase activity
AL509_29805	COG1724	mRNA binding
AL509_29820	COG2169	Transcriptional regulator
AL509_29820	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AL509_29840	COG0840	transmembrane signaling receptor activity
AL509_29845	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AL509_29850	COG0583	DNA-binding transcription factor activity
AL509_29875	COG2801	Transposase and inactivated derivatives
AL509_29910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL509_29930	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL509_29965	COG3712	iron ion homeostasis
AL509_29975	COG0602	queuosine metabolic process