locus-tag	class	description
AL520_00010	COG1522	sequence-specific DNA binding
AL520_00015	COG4772	TonB-dependent receptor
AL520_00030	COG2354	Protein conserved in bacteria
AL520_00035	COG3813	Protein conserved in bacteria
AL520_00055	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_00060	COG2851	Citrate transporter
AL520_00070	COG0642	Histidine kinase
AL520_00080	COG4566	intracellular signal transduction
AL520_00085	COG4191	Histidine kinase
AL520_00115	COG3712	iron ion homeostasis
AL520_00120	COG1595	DNA-templated transcription, initiation
AL520_00170	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AL520_00175	COG0149	triose-phosphate isomerase activity
AL520_00195	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL520_00205	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL520_00230	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL520_00235	COG2819	hydrolase of the alpha beta superfamily
AL520_00245	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AL520_00255	COG1185	polyribonucleotide nucleotidyltransferase activity
AL520_00260	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AL520_00270	COG1183	phosphatidylcholine synthase activity
AL520_00275	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AL520_00280	COG0440	acetolactate synthase activity
AL520_00285	COG0028	Belongs to the TPP enzyme family
AL520_00290	COG1289	transmembrane transporter activity
AL520_00295	COG3022	response to hydroperoxide
AL520_00300	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_00320	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL520_00355	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AL520_00360	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AL520_00365	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL520_00380	COG0601	transmembrane transport
AL520_00400	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AL520_00400	COG0517	IMP dehydrogenase activity
AL520_00405	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AL520_00410	COG0251	oxidation-reduction process
AL520_00415	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AL520_00420	COG1674	ftsk spoiiie
AL520_00425	COG0492	ferredoxin-NADP+ reductase activity
AL520_00430	COG1193	negative regulation of DNA recombination
AL520_00440	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL520_00460	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AL520_00465	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AL520_00470	COG2205	protein histidine kinase activity
AL520_00475	COG0745	RESPONSE REGULATOR receiver
AL520_00490	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL520_00495	COG3307	-O-antigen
AL520_00525	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AL520_00550	COG0612	Peptidase, M16
AL520_00560	COG0484	heat shock protein binding
AL520_00565	COG0443	Heat shock 70 kDa protein
AL520_00575	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AL520_00585	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AL520_00590	COG1420	regulation of RNA biosynthetic process
AL520_00595	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AL520_00600	COG0497	DNA recombination
AL520_00605	COG0735	belongs to the Fur family
AL520_00610	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL520_00615	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AL520_00630	COG0582	viral genome integration into host DNA
AL520_00675	COG1309	transcriptional regulator
AL520_00680	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AL520_00700	COG4372	Transposase
AL520_00710	COG1309	transcriptional regulator
AL520_00715	COG4221	oxidoreductase activity
AL520_00720	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_00815	COG3246	L-lysine catabolic process to acetate
AL520_00935	COG2814	Major facilitator Superfamily
AL520_00945	COG0583	DNA-binding transcription factor activity
AL520_00950	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AL520_01000	COG1192	Involved in chromosome partitioning
AL520_01015	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_01020	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL520_01025	COG0583	DNA-binding transcription factor activity
AL520_01040	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AL520_01095	COG0583	DNA-binding transcription factor activity
AL520_01110	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AL520_01115	COG0167	dihydroorotate dehydrogenase activity
AL520_01130	COG1414	Transcriptional regulator
AL520_01135	COG1058	Belongs to the CinA family
AL520_01135	COG1546	Belongs to the CinA family
AL520_01150	COG0513	Belongs to the DEAD box helicase family
AL520_01165	COG2814	Major facilitator Superfamily
AL520_01195	COG4783	chaperone-mediated protein folding
AL520_01210	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL520_01215	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AL520_01230	COG0006	proline dipeptidase activity
AL520_01240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL520_01265	COG0632	four-way junction helicase activity
AL520_01270	COG1090	epimerase
AL520_01280	COG2255	four-way junction helicase activity
AL520_01290	COG0745	RESPONSE REGULATOR receiver
AL520_01300	COG0514	ATP-dependent DNA helicase (RecQ)
AL520_01305	COG1294	oxidase, subunit
AL520_01315	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL520_01325	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL520_01330	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL520_01335	COG1414	Transcriptional regulator
AL520_01340	COG0850	regulation of cytokinetic process
AL520_01345	COG2894	cell division
AL520_01350	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AL520_01365	COG0488	(ABC) transporter
AL520_01370	COG2746	aminoglycoside 3-N-acetyltransferase activity
AL520_01390	COG4608	Belongs to the ABC transporter superfamily
AL520_01395	COG0444	Belongs to the ABC transporter superfamily
AL520_01400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL520_01410	COG0747	negative chemotaxis
AL520_01435	COG4638	Rieske (2fe-2S)
AL520_01440	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AL520_01460	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AL520_01465	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_01480	COG0411	ABC transporter
AL520_01485	COG0410	ABC transporter
AL520_01490	COG0463	Glycosyl transferase, family 2
AL520_01490	COG1216	Glycosyl transferase, family 2
AL520_01505	COG0800	Aldolase
AL520_01515	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AL520_01550	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AL520_01555	COG1538	Outer membrane efflux protein
AL520_01560	COG0577	efflux transmembrane transporter activity
AL520_01560	COG1136	(ABC) transporter
AL520_01565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL520_01580	COG0259	pyridoxamine-phosphate oxidase activity
AL520_01590	COG0579	oxidoreductase
AL520_01600	COG0583	DNA-binding transcription factor activity
AL520_01605	COG1960	acyl-CoA dehydrogenase activity
AL520_01615	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL520_01620	COG0531	amino acid
AL520_01625	COG0405	Gamma-glutamyltransferase
AL520_01635	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_01645	COG0114	fumarate hydratase activity
AL520_01650	COG0860	N-Acetylmuramoyl-L-alanine amidase
AL520_01660	COG0586	Pfam SNARE associated Golgi protein
AL520_01665	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AL520_01670	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AL520_01680	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AL520_01695	COG0617	tRNA 3'-terminal CCA addition
AL520_01705	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL520_01710	COG2301	Belongs to the HpcH HpaI aldolase family
AL520_01720	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
AL520_01730	COG1024	Enoyl-CoA hydratase
AL520_01740	COG1960	acyl-CoA dehydrogenase activity
AL520_01750	COG0183	Belongs to the thiolase family
AL520_01755	COG0318	PFAM AMP-dependent synthetase and ligase
AL520_01765	COG2070	2-Nitropropane dioxygenase
AL520_01795	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_01800	COG2030	dehydratase
AL520_01805	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL520_01820	COG1024	Enoyl-CoA hydratase
AL520_01825	COG0752	glycyl-tRNA synthetase alpha subunit
AL520_01830	COG0751	glycine-tRNA ligase activity
AL520_01835	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AL520_01840	COG0204	Acyl-transferase
AL520_01860	COG0242	peptide deformylase activity
AL520_01870	COG0700	Nucleoside recognition
AL520_01875	COG0469	pyruvate kinase activity
AL520_01880	COG1929	Belongs to the glycerate kinase type-1 family
AL520_01885	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AL520_01890	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL520_01905	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AL520_01930	COG2154	pterin-4-alpha-carbinolamine dehydratase
AL520_01960	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_01970	COG2982	Protein involved in outer membrane biogenesis
AL520_01975	COG1368	sulfuric ester hydrolase activity
AL520_01980	COG2818	Glycosylase
AL520_02000	COG0735	belongs to the Fur family
AL520_02015	COG0840	transmembrane signaling receptor activity
AL520_02075	COG2011	ABC-type metal ion transport system permease component
AL520_02080	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AL520_02085	COG1501	Belongs to the glycosyl hydrolase 31 family
AL520_02090	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AL520_02090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL520_02095	COG0483	inositol monophosphate 1-phosphatase activity
AL520_02100	COG0318	PFAM AMP-dependent synthetase and ligase
AL520_02105	COG1473	amidohydrolase
AL520_02120	COG2855	membrane
AL520_02125	COG1607	acyl-coa hydrolase
AL520_02130	COG2239	Acts as a magnesium transporter
AL520_02145	COG1522	sequence-specific DNA binding
AL520_02150	COG0300	oxidoreductase activity
AL520_02160	COG0028	Belongs to the TPP enzyme family
AL520_02165	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_02180	COG0653	protein targeting
AL520_02185	COG0739	heme binding
AL520_02195	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AL520_02200	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AL520_02210	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AL520_02215	COG1181	Belongs to the D-alanine--D-alanine ligase family
AL520_02220	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AL520_02225	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AL520_02235	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AL520_02240	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL520_02245	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AL520_02255	COG3116	cell division
AL520_02260	COG0275	rRNA processing
AL520_02265	COG2001	Belongs to the MraZ family
AL520_02280	COG0418	dihydroorotase activity
AL520_02285	COG1473	amidohydrolase
AL520_02325	COG1522	sequence-specific DNA binding
AL520_02335	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL520_02340	COG4654	Cytochrome c, class I
AL520_02345	COG0129	dihydroxy-acid dehydratase activity
AL520_02385	COG0405	Gamma-glutamyltransferase
AL520_02390	COG2084	Dehydrogenase
AL520_02395	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AL520_02405	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL520_02435	COG0442	prolyl-tRNA aminoacylation
AL520_02440	COG0824	Thioesterase
AL520_02445	COG0811	peptide transport
AL520_02450	COG0848	biopolymer transport protein
AL520_02460	COG0823	Involved in the tonB-independent uptake of proteins
AL520_02475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL520_02480	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AL520_02495	COG1522	sequence-specific DNA binding
AL520_02505	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AL520_02520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL520_02525	COG0697	spore germination
AL520_02540	COG1380	Effector of murein hydrolase LrgA
AL520_02545	COG0583	DNA-binding transcription factor activity
AL520_02555	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL520_02575	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL520_02595	COG0583	DNA-binding transcription factor activity
AL520_02610	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AL520_02615	COG0463	Glycosyl transferase, family 2
AL520_02625	COG0786	glutamate:sodium symporter activity
AL520_02640	COG1671	Belongs to the UPF0178 family
AL520_02650	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AL520_02655	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL520_02665	COG0328	RNA-DNA hybrid ribonuclease activity
AL520_02670	COG2226	methyltransferase
AL520_02675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL520_02680	COG0741	lytic transglycosylase activity
AL520_02680	COG1388	LysM domain
AL520_02720	COG1366	Belongs to the anti-sigma-factor antagonist family
AL520_02725	COG2172	sigma factor antagonist activity
AL520_02730	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AL520_02740	COG2770	Histidine kinase
AL520_02740	COG2208	phosphoserine phosphatase activity
AL520_02775	COG4792	protein secretion
AL520_02780	COG4791	protein targeting
AL520_02785	COG4794	Type iii secretion
AL520_02790	COG4790	Type iii secretion
AL520_02795	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AL520_02825	COG4669	(LipO)protein
AL520_02900	COG4789	Type iii secretion
AL520_02955	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL520_02970	COG1942	4-Oxalocrotonate Tautomerase
AL520_02975	COG0583	DNA-binding transcription factor activity
AL520_02985	COG2719	SpoVR family
AL520_02990	COG2718	Belongs to the UPF0229 family
AL520_02995	COG2766	serine protein kinase
AL520_03010	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL520_03010	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL520_03025	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AL520_03030	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AL520_03035	COG1280	lysine exporter protein (LysE YggA)
AL520_03045	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AL520_03055	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AL520_03060	COG0316	Belongs to the HesB IscA family
AL520_03070	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AL520_03075	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AL520_03080	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AL520_03095	COG4177	L-phenylalanine transmembrane transporter activity
AL520_03100	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL520_03110	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AL520_03115	COG0312	modulator of DNA gyrase
AL520_03120	COG3028	Belongs to the UPF0307 family
AL520_03135	COG1116	anion transmembrane transporter activity
AL520_03140	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL520_03145	COG1335	isochorismatase
AL520_03150	COG0045	succinate-CoA ligase (ADP-forming) activity
AL520_03150	COG1042	CoA-binding domain protein
AL520_03150	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL520_03155	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL520_03170	COG0583	DNA-binding transcription factor activity
AL520_03180	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_03185	COG1522	sequence-specific DNA binding
AL520_03215	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AL520_03220	COG1696	Membrane protein involved in D-alanine export
AL520_03245	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AL520_03245	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AL520_03255	COG2264	protein methyltransferase activity
AL520_03260	COG0439	Biotin carboxylase
AL520_03270	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AL520_03275	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL520_03280	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AL520_03285	COG3150	esterase
AL520_03290	COG0557	exoribonuclease II activity
AL520_03300	COG0642	Histidine kinase
AL520_03310	COG1175	transmembrane transport
AL520_03325	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AL520_03330	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AL520_03340	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AL520_03345	COG1126	abc transporter atp-binding protein
AL520_03360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL520_03370	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AL520_03380	COG3328	transposase activity
AL520_03400	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AL520_03405	COG1678	Uncharacterized ACR, COG1678
AL520_03425	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AL520_03430	COG0741	lytic transglycosylase activity
AL520_03440	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_03445	COG1335	isochorismatase
AL520_03450	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AL520_03455	COG4638	Rieske (2fe-2S)
AL520_03495	COG1024	Enoyl-CoA hydratase
AL520_03500	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_03515	COG3706	GGDEF domain
AL520_03535	COG0410	ABC transporter
AL520_03550	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL520_03570	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AL520_03590	COG3842	ATPase activity
AL520_03600	COG3833	ABC-type maltose transport systems, permease component
AL520_03615	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AL520_03655	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AL520_03660	COG0237	dephospho-CoA kinase activity
AL520_03680	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AL520_03685	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AL520_03695	COG0477	Major facilitator Superfamily
AL520_03700	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AL520_03730	COG1605	Chorismate mutase
AL520_03730	COG0077	Prephenate dehydratase
AL520_03740	COG2081	HI0933 family
AL520_03745	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL520_03770	COG1126	abc transporter atp-binding protein
AL520_03775	COG0765	amino acid transport
AL520_03780	COG4597	amino acid ABC transporter
AL520_03785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL520_03790	COG2884	Cell division ATP-binding protein ftsE
AL520_03795	COG2177	Part of the ABC transporter FtsEX involved in
AL520_03800	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AL520_03820	COG1194	a g-specific adenine glycosylase
AL520_03835	COG0246	Mannitol dehydrogenase
AL520_03840	COG4948	Mandelate Racemase Muconate Lactonizing
AL520_03845	COG1126	abc transporter atp-binding protein
AL520_03850	COG0765	amino acid transport
AL520_03860	COG1063	alcohol dehydrogenase
AL520_03875	COG2186	Transcriptional regulator
AL520_03885	COG4771	TonB-dependent receptor
AL520_03890	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL520_03895	COG2022	thiamine diphosphate biosynthetic process
AL520_03900	COG0351	phosphomethylpyrimidine kinase
AL520_03905	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AL520_03915	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AL520_03925	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AL520_03940	COG2226	methyltransferase
AL520_03945	COG0745	RESPONSE REGULATOR receiver
AL520_03970	COG2132	Multicopper oxidase
AL520_03985	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL520_04000	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AL520_04005	COG1984	allophanate hydrolase subunit 2
AL520_04010	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AL520_04015	COG1802	Transcriptional regulator
AL520_04020	COG2860	membrane
AL520_04030	COG2223	nitrite transmembrane transporter activity
AL520_04035	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AL520_04035	COG2813	Specifically methylates the guanine in position
AL520_04040	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AL520_04045	COG2188	Transcriptional regulator
AL520_04050	COG2721	sulfolactate sulfo-lyase activity
AL520_04055	COG2721	sulfolactate sulfo-lyase activity
AL520_04065	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL520_04070	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AL520_04120	COG2918	glutathione biosynthetic process
AL520_04130	COG2988	succinylglutamate desuccinylase activity
AL520_04140	COG0583	DNA-binding transcription factor activity
AL520_04150	COG1802	Transcriptional regulator
AL520_04165	COG1129	ABC transporter
AL520_04175	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL520_04185	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL520_04200	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL520_04205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL520_04210	COG1595	DNA-templated transcription, initiation
AL520_04220	COG0583	DNA-binding transcription factor activity
AL520_04225	COG1764	response to oxidative stress
AL520_04265	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL520_04280	COG1309	transcriptional regulator
AL520_04290	COG1024	Enoyl-CoA hydratase
AL520_04295	COG1024	Enoyl-CoA hydratase
AL520_04300	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AL520_04310	COG0747	negative chemotaxis
AL520_04315	COG0583	DNA-binding transcription factor activity
AL520_04325	COG2988	succinylglutamate desuccinylase activity
AL520_04330	COG0747	negative chemotaxis
AL520_04335	COG0601	transmembrane transport
AL520_04345	COG0444	Belongs to the ABC transporter superfamily
AL520_04350	COG4608	Belongs to the ABC transporter superfamily
AL520_04360	COG2195	Cleaves the N-terminal amino acid of tripeptides
AL520_04370	COG2171	N-acyltransferase activity
AL520_04380	COG4221	oxidoreductase activity
AL520_04385	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AL520_04400	COG0210	DNA helicase
AL520_04405	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AL520_04410	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AL520_04420	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AL520_04425	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AL520_04430	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AL520_04435	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AL520_04440	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AL520_04445	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AL520_04455	COG0356	it plays a direct role in the translocation of protons across the membrane
AL520_04470	COG1024	Enoyl-CoA hydratase
AL520_04475	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL520_04485	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AL520_04500	COG0583	DNA-binding transcription factor activity
AL520_04505	COG3473	Maleate cis-trans isomerase
AL520_04510	COG0583	DNA-binding transcription factor activity
AL520_04515	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AL520_04530	COG0037	tRNA processing
AL520_04535	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL520_04540	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL520_04545	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL520_04555	COG2967	ApaG domain
AL520_04565	COG0546	phosphoglycolate phosphatase activity
AL520_04575	COG0512	Glutamine amidotransferase of anthranilate synthase
AL520_04580	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AL520_04585	COG0134	indole-3-glycerol-phosphate synthase activity
AL520_04590	COG3284	Transcriptional regulator
AL520_04595	COG1012	belongs to the aldehyde dehydrogenase family
AL520_04625	COG0709	Synthesizes selenophosphate from selenide and ATP
AL520_04630	COG1305	Transglutaminase-like
AL520_04635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL520_04640	COG1215	transferase activity, transferring glycosyl groups
AL520_04650	COG3276	selenocysteine insertion sequence binding
AL520_04665	COG2864	formate dehydrogenase
AL520_04670	COG0437	4 iron, 4 sulfur cluster binding
AL520_04675	COG3383	formate dehydrogenase (NAD+) activity
AL520_04675	COG0243	molybdopterin cofactor binding
AL520_04680	COG3383	formate dehydrogenase (NAD+) activity
AL520_04680	COG0243	molybdopterin cofactor binding
AL520_04690	COG1607	acyl-coa hydrolase
AL520_04695	COG3415	Transposase
AL520_04695	COG2801	Transposase and inactivated derivatives
AL520_04715	COG3585	molybdate ion transport
AL520_04720	COG1116	anion transmembrane transporter activity
AL520_04725	COG1464	Belongs to the NlpA lipoprotein family
AL520_04730	COG2011	ABC-type metal ion transport system permease component
AL520_04745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL520_04750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL520_04755	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL520_04760	COG0431	NADPH-dependent FMN reductase
AL520_04765	COG1464	Belongs to the NlpA lipoprotein family
AL520_04770	COG3328	transposase activity
AL520_04795	COG0747	negative chemotaxis
AL520_04805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL520_04810	COG4172	Belongs to the ABC transporter superfamily
AL520_04815	COG0589	response to stress
AL520_04830	COG1012	belongs to the aldehyde dehydrogenase family
AL520_04835	COG3069	C4-dicarboxylate transmembrane transporter activity
AL520_04845	COG1802	Transcriptional regulator
AL520_04900	COG3188	usher protein
AL520_04915	COG2814	Major facilitator Superfamily
AL520_04920	COG0840	transmembrane signaling receptor activity
AL520_04940	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AL520_04945	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AL520_04970	COG0737	Belongs to the 5'-nucleotidase family
AL520_05015	COG0463	Glycosyl transferase, family 2
AL520_05020	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AL520_05040	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AL520_05045	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AL520_05050	COG5001	Diguanylate cyclase
AL520_05055	COG2423	ornithine cyclodeaminase activity
AL520_05060	COG0583	DNA-binding transcription factor activity
AL520_05065	COG2814	Major facilitator Superfamily
AL520_05070	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AL520_05075	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AL520_05085	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AL520_05115	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AL520_05130	COG0456	acetyltransferase
AL520_05140	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AL520_05160	COG2814	Major facilitator Superfamily
AL520_05165	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AL520_05185	COG1999	signal sequence binding
AL520_05190	COG0109	protoheme IX farnesyltransferase activity
AL520_05195	COG1612	heme a metabolic process
AL520_05225	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AL520_05240	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AL520_05265	COG0070	glutamate synthase
AL520_05265	COG0069	glutamate synthase activity
AL520_05265	COG0067	glutamate synthase
AL520_05290	COG1984	allophanate hydrolase subunit 2
AL520_05305	COG0511	ligase activity, forming carbon-carbon bonds
AL520_05310	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AL520_05315	COG0583	DNA-binding transcription factor activity
AL520_05330	COG0477	Major facilitator Superfamily
AL520_05345	COG1127	ABC transporter
AL520_05350	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AL520_05355	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AL520_05360	COG2853	Lipoprotein
AL520_05370	COG1131	(ABC) transporter
AL520_05375	COG0842	Transport permease protein
AL520_05385	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AL520_05390	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AL520_05395	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AL520_05400	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AL520_05405	COG0131	Imidazoleglycerol-phosphate dehydratase
AL520_05410	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AL520_05415	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AL520_05420	COG0107	imidazoleglycerol-phosphate synthase activity
AL520_05425	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AL520_05430	COG0140	phosphoribosyl-ATP diphosphatase activity
AL520_05435	COG0537	adenosine 5'-monophosphoramidase activity
AL520_05440	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AL520_05445	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AL520_05465	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AL520_05470	COG1970	mechanosensitive ion channel activity
AL520_05475	COG0723	plastoquinol--plastocyanin reductase activity
AL520_05480	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AL520_05485	COG2857	Cytochrome c1
AL520_05490	COG0625	glutathione transferase activity
AL520_05495	COG2969	positive regulation of protein catabolic process
AL520_05530	COG0583	DNA-binding transcription factor activity
AL520_05540	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AL520_05550	COG3708	Transcriptional regulator
AL520_05550	COG2207	Transcriptional regulator
AL520_05560	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AL520_05565	COG0747	negative chemotaxis
AL520_05570	COG0601	transmembrane transport
AL520_05575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL520_05585	COG1228	amidohydrolase
AL520_05590	COG5339	Protein conserved in bacteria
AL520_05595	COG5339	Protein conserved in bacteria
AL520_05600	COG0513	Belongs to the DEAD box helicase family
AL520_05605	COG1280	lysine exporter protein (LysE YggA)
AL520_05610	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AL520_05630	COG0583	DNA-binding transcription factor activity
AL520_05640	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AL520_05655	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL520_05665	COG1609	Transcriptional regulator
AL520_05670	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AL520_05675	COG3842	ATPase activity
AL520_05680	COG1653	transport
AL520_05685	COG1175	transmembrane transport
AL520_05690	COG0395	ABC-type sugar transport system, permease component
AL520_05705	COG0018	arginyl-trna synthetase
AL520_05715	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL520_05740	COG1280	lysine exporter protein (LysE YggA)
AL520_05755	COG1742	UPF0060 membrane protein
AL520_05765	COG1473	amidohydrolase
AL520_05770	COG1960	acyl-CoA dehydrogenase activity
AL520_05775	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AL520_05780	COG0183	Belongs to the thiolase family
AL520_05785	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AL520_05810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL520_05835	COG1280	lysine exporter protein (LysE YggA)
AL520_05845	COG3339	Conserved Protein
AL520_05855	COG3328	transposase activity
AL520_05870	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
AL520_05890	COG4977	sequence-specific DNA binding
AL520_05905	COG1595	DNA-templated transcription, initiation
AL520_05910	COG3712	iron ion homeostasis
AL520_05920	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AL520_05925	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_05930	COG1309	transcriptional regulator
AL520_05935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL520_05940	COG0765	amino acid transport
AL520_05945	COG0765	amino acid transport
AL520_05980	COG2922	Belongs to the Smg family
AL520_05985	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL520_06005	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AL520_06010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL520_06015	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_06020	COG0028	Belongs to the TPP enzyme family
AL520_06025	COG1522	sequence-specific DNA binding
AL520_06030	COG3781	membrane
AL520_06040	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AL520_06045	COG2814	Major facilitator Superfamily
AL520_06060	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL520_06075	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AL520_06085	COG1744	ABC transporter substrate-binding protein PnrA-like
AL520_06105	COG0402	S-adenosylhomocysteine deaminase activity
AL520_06115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL520_06120	COG0583	DNA-binding transcription factor activity
AL520_06125	COG0251	oxidation-reduction process
AL520_06150	COG1177	transmembrane transport
AL520_06155	COG1176	ABC-type spermidine putrescine transport system, permease component I
AL520_06160	COG3842	ATPase activity
AL520_06170	COG1609	Transcriptional regulator
AL520_06205	COG3328	transposase activity
AL520_06215	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL520_06230	COG1177	transmembrane transport
AL520_06235	COG1176	ABC-type spermidine putrescine transport system, permease component I
AL520_06240	COG3842	ATPase activity
AL520_06250	COG1304	FMN binding
AL520_06260	COG1254	Belongs to the acylphosphatase family
AL520_06275	COG1126	abc transporter atp-binding protein
AL520_06280	COG0765	amino acid transport
AL520_06285	COG0765	amino acid transport
AL520_06290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL520_06295	COG0583	DNA-binding transcription factor activity
AL520_06305	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AL520_06330	COG0583	DNA-binding transcription factor activity
AL520_06340	COG0592	DNA-directed DNA polymerase activity
AL520_06345	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AL520_06350	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AL520_06355	COG0594	ribonuclease P activity
AL520_06365	COG0753	catalase activity
AL520_06385	COG1473	amidohydrolase
AL520_06390	COG4608	Belongs to the ABC transporter superfamily
AL520_06395	COG0444	Belongs to the ABC transporter superfamily
AL520_06400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL520_06405	COG0601	transmembrane transport
AL520_06415	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AL520_06425	COG0038	chloride channel
AL520_06455	COG0436	Aminotransferase
AL520_06460	COG3180	Ammonia monooxygenase
AL520_06465	COG1278	Cold shock
AL520_06470	COG0445	tRNA wobble uridine modification
AL520_06475	COG0357	Ribosomal RNA small subunit methyltransferase G
AL520_06480	COG1192	Involved in chromosome partitioning
AL520_06490	COG1475	DNA binding
AL520_06495	COG0252	asparaginase activity
AL520_06500	COG0583	DNA-binding transcription factor activity
AL520_06525	COG1349	DNA-binding transcription factor activity
AL520_06535	COG3842	ATPase activity
AL520_06540	COG1840	ABC-type Fe3 transport system, periplasmic component
AL520_06580	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AL520_06590	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AL520_06600	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AL520_06605	COG0081	regulation of translation
AL520_06610	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AL520_06615	COG0222	ribosome binding
AL520_06620	COG0085	RNA polymerase activity
AL520_06625	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AL520_06640	COG5002	protein histidine kinase activity
AL520_06655	COG0745	RESPONSE REGULATOR receiver
AL520_06660	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AL520_06665	COG0049	tRNA binding
AL520_06670	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AL520_06675	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AL520_06680	COG0051	transcription antitermination factor activity, RNA binding
AL520_06685	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AL520_06690	COG0088	Forms part of the polypeptide exit tunnel
AL520_06695	COG0089	rRNA binding
AL520_06700	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AL520_06705	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AL520_06710	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AL520_06715	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AL520_06720	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AL520_06725	COG0255	Belongs to the universal ribosomal protein uL29 family
AL520_06730	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AL520_06745	COG4177	L-phenylalanine transmembrane transporter activity
AL520_06750	COG0410	ABC transporter
AL520_06755	COG0411	ABC transporter
AL520_06765	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AL520_06770	COG2207	Transcriptional regulator
AL520_06800	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AL520_06805	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AL520_06810	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AL520_06815	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AL520_06820	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AL520_06825	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AL520_06830	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AL520_06835	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AL520_06840	COG1841	ribosomal large subunit assembly
AL520_06845	COG0200	Binds to the 23S rRNA
AL520_06850	COG0201	protein transport
AL520_06855	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AL520_06860	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AL520_06865	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AL520_06870	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AL520_06875	COG0202	RNA polymerase activity
AL520_06880	COG0203	ribosomal protein L17
AL520_06890	COG1324	tolerance protein
AL520_06895	COG4232	protein-disulfide reductase activity
AL520_06910	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AL520_06920	COG1333	cytochrome c biogenesis protein
AL520_06930	COG0019	diaminopimelate decarboxylase activity
AL520_06940	COG1965	Belongs to the frataxin family
AL520_06950	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AL520_06955	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AL520_06960	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AL520_06965	COG0625	glutathione transferase activity
AL520_06975	COG2814	Major facilitator Superfamily
AL520_06980	COG0629	single-stranded DNA binding
AL520_06985	COG2226	methyltransferase
AL520_07015	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AL520_07020	COG2186	Transcriptional regulator
AL520_07035	COG1422	Protein of unknown function (DUF1090)
AL520_07045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL520_07050	COG1956	GAF domain-containing protein
AL520_07055	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL520_07070	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL520_07095	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AL520_07100	COG3568	Endonuclease Exonuclease Phosphatase
AL520_07130	COG2814	Major facilitator Superfamily
AL520_07140	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL520_07195	COG0859	PFAM glycosyl transferase family 9
AL520_07205	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AL520_07215	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AL520_07240	COG1686	Belongs to the peptidase S11 family
AL520_07250	COG2921	Belongs to the UPF0250 family
AL520_07255	COG0321	lipoyl(octanoyl) transferase activity
AL520_07265	COG1609	Transcriptional regulator
AL520_07270	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AL520_07275	COG2096	Adenosyltransferase
AL520_07285	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AL520_07290	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AL520_07295	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AL520_07300	COG0523	cobalamin synthesis protein
AL520_07305	COG0735	belongs to the Fur family
AL520_07320	COG0803	Belongs to the bacterial solute-binding protein 9 family
AL520_07330	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AL520_07335	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AL520_07345	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AL520_07350	COG1560	Kdo2-lipid A biosynthetic process
AL520_07360	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AL520_07365	COG0154	amidase activity
AL520_07405	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL520_07410	COG0583	DNA-binding transcription factor activity
AL520_07415	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_07425	COG0066	3-isopropylmalate dehydratase activity
AL520_07440	COG0438	transferase activity, transferring glycosyl groups
AL520_07445	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AL520_07450	COG1950	PFAM Membrane protein of
AL520_07470	COG1305	Transglutaminase-like
AL520_07480	COG2308	Evidence 4 Homologs of previously reported genes of
AL520_07485	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AL520_07495	COG0617	tRNA 3'-terminal CCA addition
AL520_07505	COG0513	Belongs to the DEAD box helicase family
AL520_07510	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AL520_07540	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AL520_07540	COG0351	phosphomethylpyrimidine kinase
AL520_07540	COG0352	thiamine-phosphate diphosphorylase activity
AL520_07545	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_07565	COG3189	MarR family transcriptional regulator
AL520_07570	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AL520_07580	COG0297	glycogen (starch) synthase activity
AL520_07605	COG0640	Transcriptional regulator
AL520_07665	COG1846	Transcriptional regulator
AL520_07670	COG1764	response to oxidative stress
AL520_07680	COG0411	ABC transporter
AL520_07695	COG0583	DNA-binding transcription factor activity
AL520_07710	COG0583	DNA-binding transcription factor activity
AL520_07730	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AL520_07735	COG0708	Exodeoxyribonuclease III
AL520_07740	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AL520_07750	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AL520_07755	COG0154	amidase activity
AL520_07760	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AL520_07765	COG1077	Cell shape determining protein MreB Mrl
AL520_07770	COG1792	Involved in formation and maintenance of cell shape
AL520_07780	COG0768	penicillin binding
AL520_07785	COG0772	Belongs to the SEDS family
AL520_07790	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AL520_07795	COG0471	metal ion transport
AL520_07800	COG1309	transcriptional regulator
AL520_07810	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AL520_07820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL520_07830	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AL520_07845	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AL520_07855	COG1660	Displays ATPase and GTPase activities
AL520_07870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL520_07875	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AL520_07885	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AL520_07890	COG1137	ATPase activity
AL520_07905	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AL520_07915	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AL520_07930	COG1294	oxidase, subunit
AL520_07935	COG4988	ABC transporter
AL520_07940	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AL520_07945	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AL520_07960	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL520_07965	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AL520_07970	COG1238	metal cluster binding
AL520_07985	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_07990	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AL520_07995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL520_08000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL520_08015	COG0758	DNA mediated transformation
AL520_08020	COG0242	peptide deformylase activity
AL520_08025	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AL520_08035	COG0546	phosphoglycolate phosphatase activity
AL520_08055	COG1733	regulation of RNA biosynthetic process
AL520_08060	COG2076	Multidrug Resistance protein
AL520_08070	COG1280	lysine exporter protein (LysE YggA)
AL520_08075	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AL520_08075	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AL520_08085	COG5000	phosphorelay sensor kinase activity
AL520_08090	COG2204	response regulator
AL520_08095	COG0569	domain protein
AL520_08100	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AL520_08105	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AL520_08110	COG2226	methyltransferase
AL520_08115	COG1040	competence protein
AL520_08130	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AL520_08135	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AL520_08140	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AL520_08150	COG0588	phosphoglycerate mutase activity
AL520_08155	COG4942	peptidase
AL520_08160	COG0793	Belongs to the peptidase S41A family
AL520_08165	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AL520_08170	COG5002	protein histidine kinase activity
AL520_08170	COG5001	Diguanylate cyclase
AL520_08170	COG3447	MASE1 domain protein
AL520_08175	COG2186	Transcriptional regulator
AL520_08185	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AL520_08190	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL520_08190	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL520_08205	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AL520_08210	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AL520_08215	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AL520_08220	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AL520_08225	COG0142	geranyltranstransferase activity
AL520_08245	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL520_08280	COG0235	Class ii aldolase
AL520_08285	COG3622	Belongs to the hyi family
AL520_08290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL520_08295	COG2084	Dehydrogenase
AL520_08300	COG3395	kinase activity
AL520_08305	COG2186	Transcriptional regulator
AL520_08330	COG3622	Belongs to the hyi family
AL520_08350	COG1522	sequence-specific DNA binding
AL520_08355	COG1280	lysine exporter protein (LysE YggA)
AL520_08365	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AL520_08370	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AL520_08375	COG2890	protein-(glutamine-N5) methyltransferase activity
AL520_08380	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AL520_08395	COG1464	Belongs to the NlpA lipoprotein family
AL520_08415	COG0318	PFAM AMP-dependent synthetase and ligase
AL520_08440	COG0477	Major facilitator Superfamily
AL520_08445	COG0583	DNA-binding transcription factor activity
AL520_08455	COG0583	DNA-binding transcription factor activity
AL520_08470	COG0625	glutathione transferase activity
AL520_08505	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL520_08515	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_08520	COG1802	Transcriptional regulator
AL520_08525	COG0288	reversible hydration of carbon dioxide
AL520_08545	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AL520_08560	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AL520_08570	COG1414	Transcriptional regulator
AL520_08575	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_08580	COG2031	fatty acid transporter
AL520_08585	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL520_08590	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AL520_08595	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AL520_08600	COG3300	MHYT domain
AL520_08600	COG5001	Diguanylate cyclase
AL520_08610	COG0583	DNA-binding transcription factor activity
AL520_08615	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL520_08625	COG0129	dihydroxy-acid dehydratase activity
AL520_08630	COG0583	DNA-binding transcription factor activity
AL520_08635	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL520_08650	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AL520_08655	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_08660	COG0410	ABC transporter
AL520_08665	COG0411	ABC transporter
AL520_08675	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL520_08685	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AL520_08695	COG2186	Transcriptional regulator
AL520_08705	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
AL520_08725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL520_08730	COG0583	DNA-binding transcription factor activity
AL520_08735	COG0628	permease
AL520_08755	COG1176	ABC-type spermidine putrescine transport system, permease component I
AL520_08760	COG3842	ATPase activity
AL520_08770	COG0277	FAD linked oxidase domain protein
AL520_08785	COG0477	Major facilitator Superfamily
AL520_08805	COG1695	Transcriptional regulator
AL520_08815	COG0583	DNA-binding transcription factor activity
AL520_08835	COG0745	RESPONSE REGULATOR receiver
AL520_08840	COG0784	Response regulator, receiver
AL520_08840	COG2198	Histidine kinase
AL520_08840	COG5002	protein histidine kinase activity
AL520_08945	COG0583	DNA-binding transcription factor activity
AL520_08950	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_08960	COG3246	L-lysine catabolic process to acetate
AL520_08965	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AL520_08970	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL520_08985	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL520_08990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL520_09055	COG0582	viral genome integration into host DNA
AL520_09095	COG0629	single-stranded DNA binding
AL520_09225	COG3566	protein conserved in bacteria
AL520_09420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL520_09425	COG0501	Belongs to the peptidase M48B family
AL520_09455	COG0542	response to heat
AL520_09480	COG0071	Belongs to the small heat shock protein (HSP20) family
AL520_09505	COG0556	nucleotide-excision repair
AL520_09520	COG2233	PERMEase
AL520_09530	COG0326	Molecular chaperone. Has ATPase activity
AL520_09535	COG1396	sequence-specific DNA binding
AL520_09540	COG3550	peptidyl-serine autophosphorylation
AL520_09550	COG4774	siderophore transport
AL520_09565	COG1131	(ABC) transporter
AL520_09570	COG2271	Major facilitator Superfamily
AL520_09575	COG4948	Mandelate Racemase Muconate Lactonizing
AL520_09580	COG0800	Aldolase
AL520_09590	COG1414	Transcriptional regulator
AL520_09635	COG1012	belongs to the aldehyde dehydrogenase family
AL520_09660	COG0625	glutathione transferase activity
AL520_09680	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AL520_09685	COG1652	LysM domain
AL520_09700	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AL520_09705	COG0583	DNA-binding transcription factor activity
AL520_09710	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL520_09715	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL520_09730	COG0582	viral genome integration into host DNA
AL520_09805	COG2003	Belongs to the UPF0758 family
AL520_09865	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AL520_09870	COG0464	growth
AL520_09885	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AL520_09970	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AL520_09975	COG0443	Heat shock 70 kDa protein
AL520_09995	COG3344	reverse transcriptase
AL520_10055	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AL520_10100	COG1192	Involved in chromosome partitioning
AL520_10115	COG0583	DNA-binding transcription factor activity
AL520_10120	COG0583	DNA-binding transcription factor activity
AL520_10145	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AL520_10165	COG3246	L-lysine catabolic process to acetate
AL520_10170	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_10175	COG2205	protein histidine kinase activity
AL520_10180	COG0165	Argininosuccinate lyase
AL520_10190	COG2828	Protein conserved in bacteria
AL520_10205	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AL520_10245	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AL520_10260	COG0477	Major facilitator Superfamily
AL520_10265	COG0625	glutathione transferase activity
AL520_10275	COG3258	Cytochrome c
AL520_10280	COG0583	DNA-binding transcription factor activity
AL520_10310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL520_10315	COG1294	oxidase, subunit
AL520_10320	COG1271	oxidase subunit
AL520_10325	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_10335	COG0842	Transport permease protein
AL520_10345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL520_10355	COG3243	poly(R)-hydroxyalkanoic acid synthase
AL520_10365	COG2200	EAL domain
AL520_10390	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AL520_10395	COG0745	RESPONSE REGULATOR receiver
AL520_10425	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL520_10425	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL520_10435	COG0489	protein tyrosine kinase activity
AL520_10450	COG0717	Belongs to the dCTP deaminase family
AL520_10460	COG3706	GGDEF domain
AL520_10475	COG1982	Orn Lys Arg decarboxylase major
AL520_10480	COG2081	HI0933 family
AL520_10495	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AL520_10500	COG0509	glycine decarboxylation via glycine cleavage system
AL520_10505	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AL520_10505	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AL520_10520	COG0154	amidase activity
AL520_10525	COG4172	Belongs to the ABC transporter superfamily
AL520_10530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL520_10535	COG0601	transmembrane transport
AL520_10540	COG0747	negative chemotaxis
AL520_10560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL520_10575	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AL520_10585	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
AL520_10590	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL520_10595	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AL520_10610	COG0438	transferase activity, transferring glycosyl groups
AL520_10620	COG0438	transferase activity, transferring glycosyl groups
AL520_10625	COG0438	transferase activity, transferring glycosyl groups
AL520_10635	COG0405	Gamma-glutamyltransferase
AL520_10640	COG0166	Belongs to the GPI family
AL520_10655	COG0277	FAD linked oxidase domain protein
AL520_10660	COG0745	RESPONSE REGULATOR receiver
AL520_10665	COG2205	protein histidine kinase activity
AL520_10675	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL520_10685	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL520_10695	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL520_10700	COG2186	Transcriptional regulator
AL520_10705	COG1368	sulfuric ester hydrolase activity
AL520_10710	COG0204	Acyl-transferase
AL520_10720	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AL520_10745	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AL520_10755	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AL520_10760	COG0840	transmembrane signaling receptor activity
AL520_10765	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AL520_10775	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AL520_10780	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AL520_10785	COG0193	aminoacyl-tRNA hydrolase activity
AL520_10795	COG0012	GTP binding
AL520_10800	COG0582	viral genome integration into host DNA
AL520_10820	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AL520_10855	COG2814	Major facilitator Superfamily
AL520_10870	COG3135	benzoate transporter
AL520_10875	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL520_10880	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AL520_10885	COG0742	ribosomal rna small subunit methyltransferase
AL520_10905	COG3639	organic phosphonate transmembrane transporter activity
AL520_10910	COG3639	organic phosphonate transmembrane transporter activity
AL520_10915	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AL520_10940	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AL520_10945	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AL520_10950	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AL520_10955	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AL520_10960	COG1546	Belongs to the CinA family
AL520_10965	COG0284	orotidine-5'-phosphate decarboxylase activity
AL520_10970	COG1252	NADH dehydrogenase
AL520_10975	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AL520_10980	COG0246	Mannitol dehydrogenase
AL520_10985	COG0410	ABC transporter
AL520_10990	COG1137	ATPase activity
AL520_11030	COG1846	Transcriptional regulator
AL520_11040	COG0459	protein refolding
AL520_11085	COG1686	Belongs to the peptidase S11 family
AL520_11105	COG4191	Histidine kinase
AL520_11130	COG2200	EAL domain
AL520_11175	COG0793	Belongs to the peptidase S41A family
AL520_11205	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AL520_11215	COG0745	RESPONSE REGULATOR receiver
AL520_11250	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL520_11285	COG0697	spore germination
AL520_11305	COG0431	NADPH-dependent FMN reductase
AL520_11310	COG1393	Belongs to the ArsC family
AL520_11315	COG0798	PFAM Bile acid sodium symporter
AL520_11330	COG1793	dna ligase
AL520_11335	COG1201	RNA secondary structure unwinding
AL520_11365	COG1230	cation diffusion facilitator family transporter
AL520_11385	COG0028	Belongs to the TPP enzyme family
AL520_11430	COG0596	Alpha beta hydrolase
AL520_11440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL520_11465	COG0740	serine-type endopeptidase activity
AL520_11475	COG0640	Transcriptional regulator
AL520_11480	COG2199	diguanylate cyclase activity
AL520_11480	COG2203	Gaf domain
AL520_11485	COG0840	transmembrane signaling receptor activity
AL520_11515	COG0454	-acetyltransferase
AL520_11515	COG0456	acetyltransferase
AL520_11525	COG0023	Translation Initiation Factor
AL520_11530	COG0583	DNA-binding transcription factor activity
AL520_11535	COG0656	L-ascorbic acid biosynthetic process
AL520_11540	COG0667	Aldo Keto reductase
AL520_11550	COG2146	nitrite reductase [NAD(P)H] activity
AL520_11550	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL520_11555	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL520_11555	COG2146	nitrite reductase [NAD(P)H] activity
AL520_11560	COG3707	response regulator
AL520_11580	COG2197	response regulator
AL520_11615	COG2814	Major facilitator Superfamily
AL520_11625	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL520_11630	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL520_11640	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AL520_11645	COG1845	cytochrome c oxidase, subunit III
AL520_11650	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AL520_11655	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AL520_11660	COG0477	Major facilitator Superfamily
AL520_11695	COG0583	DNA-binding transcription factor activity
AL520_11710	COG4106	trans-aconitate 2-methyltransferase activity
AL520_11715	COG2207	Transcriptional regulator
AL520_11720	COG2807	transmembrane transport
AL520_11745	COG0330	HflC and HflK could
AL520_11750	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL520_11765	COG3712	iron ion homeostasis
AL520_11780	COG3712	iron ion homeostasis
AL520_11795	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AL520_11805	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AL520_11810	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL520_11815	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_11820	COG1285	pathogenesis
AL520_11825	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AL520_11840	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AL520_11845	COG3145	DNA-N1-methyladenine dioxygenase activity
AL520_11855	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL520_11865	COG0456	acetyltransferase
AL520_11880	COG0583	DNA-binding transcription factor activity
AL520_11890	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_11925	COG0697	spore germination
AL520_11940	COG0281	malic enzyme
AL520_11940	COG0280	phosphate acetyltransferase
AL520_11980	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AL520_11985	COG1845	cytochrome c oxidase, subunit III
AL520_11990	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AL520_12000	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AL520_12020	COG1999	signal sequence binding
AL520_12050	COG0765	amino acid transport
AL520_12055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL520_12060	COG3191	aminopeptidase activity
AL520_12065	COG1272	protein, Hemolysin III
AL520_12070	COG1522	sequence-specific DNA binding
AL520_12080	COG1113	amino acid transport
AL520_12110	COG2378	regulation of single-species biofilm formation
AL520_12140	COG1595	DNA-templated transcription, initiation
AL520_12145	COG3712	iron ion homeostasis
AL520_12155	COG3720	iron ion transport
AL520_12160	COG4558	Periplasmic binding protein
AL520_12165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL520_12170	COG1120	ATPase activity
AL520_12175	COG1666	GTP binding
AL520_12195	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AL520_12200	COG0671	phosphoesterase, PA-phosphatase related
AL520_12215	COG4774	siderophore transport
AL520_12225	COG0410	ABC transporter
AL520_12230	COG0411	ABC transporter
AL520_12240	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL520_12280	COG0456	acetyltransferase
AL520_12285	COG0583	DNA-binding transcription factor activity
AL520_12290	COG2828	Protein conserved in bacteria
AL520_12310	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_12340	COG0745	RESPONSE REGULATOR receiver
AL520_12345	COG2205	protein histidine kinase activity
AL520_12360	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AL520_12365	COG0583	DNA-binding transcription factor activity
AL520_12400	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AL520_12405	COG3383	formate dehydrogenase (NAD+) activity
AL520_12425	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AL520_12435	COG0303	'Molybdopterin
AL520_12440	COG0521	Mo-molybdopterin cofactor biosynthetic process
AL520_12445	COG0314	molybdopterin synthase activity
AL520_12455	COG0315	cyclic pyranopterin monophosphate synthase activity
AL520_12465	COG0412	Dienelactone hydrolase
AL520_12475	COG0678	peroxiredoxin activity
AL520_12485	COG0697	spore germination
AL520_12490	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AL520_12530	COG0667	Aldo Keto reductase
AL520_12535	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AL520_12540	COG4535	Mg2 and Co2 transporter CorC
AL520_12545	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AL520_12550	COG1702	phosphate starvation-inducible protein PhoH
AL520_12555	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AL520_12565	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AL520_12575	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL520_12580	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL520_12585	COG1862	Preprotein translocase
AL520_12590	COG3077	Addiction module antitoxin, RelB DinJ family
AL520_12600	COG0343	queuine tRNA-ribosyltransferase activity
AL520_12605	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AL520_12615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL520_12630	COG2027	D-alanyl-D-alanine carboxypeptidase
AL520_12635	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AL520_12640	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AL520_12640	COG1648	precorrin-2 dehydrogenase activity
AL520_12645	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL520_12650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL520_12655	COG1116	anion transmembrane transporter activity
AL520_12665	COG4575	ribosome binding
AL520_12680	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AL520_12685	COG0741	lytic transglycosylase activity
AL520_12695	COG0436	Aminotransferase
AL520_12705	COG0281	malic enzyme
AL520_12705	COG0280	phosphate acetyltransferase
AL520_12715	COG2732	(Barnase) inhibitor
AL520_12720	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AL520_12730	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AL520_12735	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AL520_12740	COG0126	phosphoglycerate kinase activity
AL520_12755	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AL520_12760	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AL520_12780	COG0625	glutathione transferase activity
AL520_12815	COG0306	phosphate transporter
AL520_12825	COG0521	Mo-molybdopterin cofactor biosynthetic process
AL520_12835	COG0739	heme binding
AL520_12845	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AL520_12855	COG0640	Transcriptional regulator
AL520_12865	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AL520_12870	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AL520_12875	COG3639	organic phosphonate transmembrane transporter activity
AL520_12895	COG0583	DNA-binding transcription factor activity
AL520_12900	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AL520_12910	COG3454	Phosphonate metabolism
AL520_12915	COG2188	Transcriptional regulator
AL520_12920	COG3624	Phosphonate C-P lyase system protein PhnG
AL520_12925	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AL520_12930	COG3626	phosphonate metabolism
AL520_12935	COG3627	carbon phosphorus lyase activity
AL520_12940	COG4107	phosphonate C-P lyase system protein PhnK
AL520_12945	COG4778	phosphonate C-P lyase system protein PhnL
AL520_12950	COG3454	Phosphonate metabolism
AL520_12970	COG1301	dicarboxylic acid transport
AL520_12990	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AL520_12995	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AL520_13000	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AL520_13005	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AL520_13010	COG0009	L-threonylcarbamoyladenylate synthase
AL520_13015	COG1414	Transcriptional regulator
AL520_13020	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AL520_13035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL520_13040	COG1414	Transcriptional regulator
AL520_13045	COG0010	Belongs to the arginase family
AL520_13055	COG0765	amino acid transport
AL520_13060	COG1126	abc transporter atp-binding protein
AL520_13065	COG0028	Belongs to the TPP enzyme family
AL520_13075	COG0411	ABC transporter
AL520_13110	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AL520_13130	COG2030	dehydratase
AL520_13165	COG0028	Belongs to the TPP enzyme family
AL520_13170	COG0583	DNA-binding transcription factor activity
AL520_13175	COG4974	Belongs to the 'phage' integrase family
AL520_13180	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AL520_13370	COG4695	Portal protein
AL520_13385	COG0318	PFAM AMP-dependent synthetase and ligase
AL520_13390	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL520_13400	COG1024	Enoyl-CoA hydratase
AL520_13405	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL520_13425	COG2070	2-Nitropropane dioxygenase
AL520_13450	COG2801	Transposase and inactivated derivatives
AL520_13450	COG3415	Transposase
AL520_13470	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AL520_13475	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL520_13480	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL520_13490	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL520_13505	COG0745	RESPONSE REGULATOR receiver
AL520_13520	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AL520_13525	COG0505	Belongs to the CarA family
AL520_13530	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AL520_13540	COG4221	oxidoreductase activity
AL520_13545	COG0406	alpha-ribazole phosphatase activity
AL520_13565	COG1840	ABC-type Fe3 transport system, periplasmic component
AL520_13575	COG2233	PERMEase
AL520_13580	COG0840	transmembrane signaling receptor activity
AL520_13585	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL520_13590	COG1534	Rna-binding protein
AL520_13595	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AL520_13600	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AL520_13610	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AL520_13645	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AL520_13660	COG0477	Major facilitator Superfamily
AL520_13665	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL520_13680	COG2841	Protein conserved in bacteria
AL520_13695	COG1595	DNA-templated transcription, initiation
AL520_13705	COG2207	Transcriptional regulator
AL520_13710	COG0667	Aldo Keto reductase
AL520_13730	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AL520_13735	COG0500	methyltransferase
AL520_13765	COG0517	IMP dehydrogenase activity
AL520_13775	COG3938	Belongs to the proline racemase family
AL520_13780	COG1177	transmembrane transport
AL520_13785	COG1176	ABC-type spermidine putrescine transport system, permease component I
AL520_13790	COG3842	ATPase activity
AL520_13845	COG3264	Mechanosensitive ion channel
AL520_13845	COG1511	domain protein
AL520_13850	COG0583	DNA-binding transcription factor activity
AL520_13855	COG0427	acetyl-CoA hydrolase
AL520_13860	COG0583	DNA-binding transcription factor activity
AL520_13895	COG2204	response regulator
AL520_13900	COG4191	Histidine kinase
AL520_13905	COG1301	dicarboxylic acid transport
AL520_13910	COG0424	maF-like protein
AL520_13915	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AL520_13920	COG0799	negative regulation of ribosome biogenesis
AL520_13925	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AL520_13930	COG0408	coproporphyrinogen oxidase activity
AL520_13935	COG0151	Belongs to the GarS family
AL520_13940	COG0217	transcriptional regulatory protein
AL520_13945	COG0433	COG0433 Predicted ATPase
AL520_13950	COG0473	3-isopropylmalate dehydrogenase activity
AL520_13960	COG2814	Major facilitator Superfamily
AL520_13965	COG1566	PFAM secretion protein HlyD family protein
AL520_13975	COG1846	Transcriptional regulator
AL520_14005	COG3391	amine dehydrogenase activity
AL520_14015	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AL520_14035	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AL520_14040	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AL520_14055	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AL520_14065	COG0187	DNA topoisomerase II activity
AL520_14080	COG1309	transcriptional regulator
AL520_14085	COG2311	Membrane
AL520_14090	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AL520_14110	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL520_14115	COG0662	Cupin 2, conserved barrel domain protein
AL520_14120	COG5285	phytanoyl-CoA dioxygenase
AL520_14125	COG0633	Ferredoxin
AL520_14125	COG3217	Mosc domain protein beta barrel domain protein
AL520_14130	COG2076	Multidrug Resistance protein
AL520_14135	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AL520_14145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL520_14160	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AL520_14165	COG0425	Belongs to the sulfur carrier protein TusA family
AL520_14175	COG0228	four-way junction DNA binding
AL520_14180	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AL520_14185	COG0336	Belongs to the RNA methyltransferase TrmD family
AL520_14195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL520_14200	COG0765	amino acid transport
AL520_14210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL520_14215	COG0525	valine-tRNA ligase activity
AL520_14220	COG0105	UTP biosynthetic process
AL520_14225	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AL520_14235	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AL520_14240	COG0124	histidyl-tRNA synthetase
AL520_14245	COG2976	Protein conserved in bacteria
AL520_14250	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL520_14255	COG1160	GTP binding
AL520_14260	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AL520_14265	COG1923	regulation of RNA biosynthetic process
AL520_14270	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AL520_14275	COG0330	HflC and HflK could
AL520_14280	COG0330	HflC and HflK could
AL520_14285	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AL520_14290	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AL520_14295	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AL520_14300	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AL520_14320	COG0582	viral genome integration into host DNA
AL520_14360	COG0419	ATPase involved in DNA repair
AL520_14410	COG1396	sequence-specific DNA binding
AL520_14475	COG5410	chromosome segregation
AL520_14645	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
AL520_14655	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL520_14665	COG2391	methyltransferase activity
AL520_14670	COG0679	Auxin Efflux Carrier
AL520_14680	COG2153	protein acetylation
AL520_14700	COG0557	exoribonuclease II activity
AL520_14705	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL520_14710	COG2873	o-acetylhomoserine
AL520_14715	COG3128	pkhd-type hydroxylase
AL520_14720	COG0776	regulation of translation
AL520_14740	COG0745	RESPONSE REGULATOR receiver
AL520_14745	COG0642	Histidine kinase
AL520_14750	COG3158	transport of potassium into the cell
AL520_14760	COG0137	argininosuccinate synthase activity
AL520_14765	COG1538	Outer membrane efflux protein
AL520_14770	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL520_14780	COG5002	protein histidine kinase activity
AL520_14785	COG0583	DNA-binding transcription factor activity
AL520_14790	COG3618	amidohydrolase
AL520_14810	COG0596	Alpha beta hydrolase
AL520_14810	COG2945	thiolester hydrolase activity
AL520_14815	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AL520_14820	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AL520_14840	COG0747	negative chemotaxis
AL520_14850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL520_14870	COG4608	Belongs to the ABC transporter superfamily
AL520_14890	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL520_14895	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AL520_14905	COG3642	lipopolysaccharide core region biosynthetic process
AL520_14915	COG3842	ATPase activity
AL520_14920	COG1176	ABC-type spermidine putrescine transport system, permease component I
AL520_14925	COG1177	transmembrane transport
AL520_14955	COG1960	acyl-CoA dehydrogenase activity
AL520_14965	COG0704	Plays a role in the regulation of phosphate uptake
AL520_14975	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AL520_14980	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AL520_14980	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AL520_14985	COG1643	Atp-dependent helicase
AL520_14990	COG0395	ABC-type sugar transport system, permease component
AL520_14995	COG1116	anion transmembrane transporter activity
AL520_15010	COG0438	transferase activity, transferring glycosyl groups
AL520_15015	COG0726	polysaccharide deacetylase
AL520_15030	COG0726	polysaccharide deacetylase
AL520_15055	COG1132	(ABC) transporter
AL520_15060	COG0475	glutathione-regulated potassium exporter activity
AL520_15060	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AL520_15075	COG2203	Gaf domain
AL520_15075	COG3706	GGDEF domain
AL520_15075	COG4251	negative regulation of phosphorylation
AL520_15075	COG5001	Diguanylate cyclase
AL520_15085	COG1530	ribonuclease E activity
AL520_15125	COG0583	DNA-binding transcription factor activity
AL520_15140	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL520_15150	COG0477	Major facilitator Superfamily
AL520_15160	COG0154	amidase activity
AL520_15180	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AL520_15195	COG0495	leucyl-tRNA aminoacylation
AL520_15200	COG1846	Transcriptional regulator
AL520_15210	COG1686	Belongs to the peptidase S11 family
AL520_15245	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AL520_15250	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AL520_15255	COG2814	Major facilitator Superfamily
AL520_15260	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL520_15270	COG4176	ABC-type proline glycine betaine transport system permease component
AL520_15275	COG4175	Glycine betaine
AL520_15275	COG3448	diguanylate cyclase activity
AL520_15290	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL520_15295	COG2706	6-phosphogluconolactonase activity
AL520_15300	COG4214	carbohydrate transport
AL520_15305	COG1129	ABC transporter
AL520_15310	COG4213	ABC transporter substrate-binding protein
AL520_15335	COG0583	DNA-binding transcription factor activity
AL520_15340	COG1960	acyl-CoA dehydrogenase activity
AL520_15345	COG1960	acyl-CoA dehydrogenase activity
AL520_15350	COG0183	Belongs to the thiolase family
AL520_15360	COG1802	Transcriptional regulator
AL520_15370	COG1024	Enoyl-CoA hydratase
AL520_15375	COG0318	PFAM AMP-dependent synthetase and ligase
AL520_15385	COG0667	Aldo Keto reductase
AL520_15395	COG4120	Belongs to the binding-protein-dependent transport system permease family
AL520_15410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL520_15420	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AL520_15440	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AL520_15445	COG0725	ABC transporter, periplasmic molybdate-binding protein
AL520_15450	COG4149	molybdate abc transporter
AL520_15455	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AL520_15480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL520_15485	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL520_15490	COG1538	Outer membrane efflux protein
AL520_15495	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AL520_15500	COG0736	holo-[acyl-carrier-protein] synthase activity
AL520_15505	COG1472	Belongs to the glycosyl hydrolase 3 family
AL520_15510	COG0322	excinuclease ABC activity
AL520_15515	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AL520_15525	COG0473	3-isopropylmalate dehydrogenase activity
AL520_15530	COG0583	DNA-binding transcription factor activity
AL520_15535	COG1858	cytochrome C peroxidase
AL520_15540	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AL520_15540	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AL520_15545	COG2224	Isocitrate lyase
AL520_15550	COG0583	DNA-binding transcription factor activity
AL520_15565	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AL520_15595	COG0156	8-amino-7-oxononanoate synthase activity
AL520_15600	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AL520_15615	COG3278	Belongs to the heme-copper respiratory oxidase family
AL520_15635	COG0348	domain, Protein
AL520_15680	COG1012	belongs to the aldehyde dehydrogenase family
AL520_15690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL520_15700	COG0765	amino acid transport
AL520_15705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL520_15710	COG1396	sequence-specific DNA binding
AL520_15735	COG3546	catalase activity
AL520_15755	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AL520_15760	COG0438	transferase activity, transferring glycosyl groups
AL520_15780	COG1566	PFAM secretion protein HlyD family protein
AL520_15795	COG0583	DNA-binding transcription factor activity
AL520_15800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL520_15805	COG0586	Pfam SNARE associated Golgi protein
AL520_15810	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL520_15825	COG4608	Belongs to the ABC transporter superfamily
AL520_15830	COG0444	Belongs to the ABC transporter superfamily
AL520_15835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL520_15840	COG0601	transmembrane transport
AL520_15845	COG0583	DNA-binding transcription factor activity
AL520_15850	COG1764	response to oxidative stress
AL520_15855	COG2205	protein histidine kinase activity
AL520_15860	COG0745	RESPONSE REGULATOR receiver
AL520_15895	COG1802	Transcriptional regulator
AL520_15915	COG2084	Dehydrogenase
AL520_15925	COG1917	Cupin 2, conserved barrel domain protein
AL520_15925	COG2207	Transcriptional regulator
AL520_15960	COG1280	lysine exporter protein (LysE YggA)
AL520_15965	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_15970	COG0840	transmembrane signaling receptor activity
AL520_16005	COG3121	Chaperone
AL520_16010	COG3188	usher protein
AL520_16025	COG0745	RESPONSE REGULATOR receiver
AL520_16035	COG1475	DNA binding
AL520_16040	COG3969	phosphoadenosine phosphosulfate
AL520_16045	COG1971	Probably functions as a manganese efflux pump
AL520_16050	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL520_16105	COG2321	neutral zinc metallopeptidase
AL520_16110	COG0009	L-threonylcarbamoyladenylate synthase
AL520_16115	COG1994	Peptidase M50
AL520_16120	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL520_16125	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AL520_16135	COG2850	peptidyl-arginine hydroxylation
AL520_16140	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AL520_16200	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_16205	COG0583	DNA-binding transcription factor activity
AL520_16215	COG3360	Dodecin
AL520_16255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL520_16260	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL520_16300	COG0668	transmembrane transport
AL520_16335	COG1253	flavin adenine dinucleotide binding
AL520_16340	COG1968	undecaprenyl-diphosphatase activity
AL520_16345	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL520_16350	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AL520_16360	COG0215	cysteine-tRNA ligase activity
AL520_16370	COG0825	malonyl-CoA metabolic process
AL520_16375	COG0037	tRNA processing
AL520_16380	COG0527	aspartate kinase activity
AL520_16395	COG0348	domain, Protein
AL520_16410	COG3278	Belongs to the heme-copper respiratory oxidase family
AL520_16420	COG2217	Heavy metal translocating P-type atpase
AL520_16425	COG3258	Cytochrome c
AL520_16430	COG2863	cytochrome
AL520_16445	COG0784	Response regulator, receiver
AL520_16445	COG2205	protein histidine kinase activity
AL520_16455	COG2205	protein histidine kinase activity
AL520_16455	COG0784	Response regulator, receiver
AL520_16465	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AL520_16475	COG1309	transcriptional regulator
AL520_16505	COG0456	acetyltransferase
AL520_16515	COG0583	DNA-binding transcription factor activity
AL520_16540	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AL520_16550	COG1414	Transcriptional regulator
AL520_16560	COG1024	Enoyl-CoA hydratase
AL520_16565	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AL520_16570	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AL520_16580	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AL520_16585	COG3395	kinase activity
AL520_16595	COG1132	(ABC) transporter
AL520_16605	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_16615	COG0318	PFAM AMP-dependent synthetase and ligase
AL520_16630	COG0183	Belongs to the thiolase family
AL520_16635	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL520_16635	COG1024	Enoyl-CoA hydratase
AL520_16645	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL520_16645	COG1024	Enoyl-CoA hydratase
AL520_16660	COG1309	transcriptional regulator
AL520_16670	COG2197	response regulator
AL520_16675	COG2197	response regulator
AL520_16680	COG0297	glycogen (starch) synthase activity
AL520_16685	COG0110	maltose O-acetyltransferase activity
AL520_16690	COG0463	Glycosyl transferase, family 2
AL520_16715	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL520_16735	COG1051	belongs to the nudix hydrolase family
AL520_16740	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AL520_16760	COG0166	Belongs to the GPI family
AL520_16765	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AL520_16770	COG1045	serine acetyltransferase
AL520_16775	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AL520_16780	COG0483	inositol monophosphate 1-phosphatase activity
AL520_16790	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL520_16810	COG0598	Magnesium transport protein CorA
AL520_16830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL520_16835	COG4172	Belongs to the ABC transporter superfamily
AL520_16840	COG1846	Transcriptional regulator
AL520_16885	COG4964	Belongs to the GSP D family
AL520_16940	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AL520_16955	COG3384	dioxygenase
AL520_16960	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AL520_16960	COG2885	chlorophyll binding
AL520_16965	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AL520_16975	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_17005	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_17010	COG0604	alcohol dehydrogenase
AL520_17010	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_17010	COG3321	synthase
AL520_17015	COG0410	ABC transporter
AL520_17025	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL520_17035	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_17045	COG3246	L-lysine catabolic process to acetate
AL520_17050	COG0371	Dehydrogenase
AL520_17055	COG1802	Transcriptional regulator
AL520_17060	COG3959	Transketolase, thiamine diphosphate binding domain
AL520_17065	COG3958	Transketolase
AL520_17070	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AL520_17080	COG4948	Mandelate Racemase Muconate Lactonizing
AL520_17095	COG0765	amino acid transport
AL520_17105	COG2721	sulfolactate sulfo-lyase activity
AL520_17115	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_17120	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL520_17125	COG1414	Transcriptional regulator
AL520_17160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL520_17190	COG4206	TonB-dependent receptor
AL520_17195	COG4206	TonB-dependent receptor
AL520_17200	COG4774	siderophore transport
AL520_17210	COG1595	DNA-templated transcription, initiation
AL520_17215	COG0477	Major facilitator Superfamily
AL520_17225	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL520_17235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL520_17260	COG3852	Histidine kinase
AL520_17270	COG1546	Belongs to the CinA family
AL520_17270	COG1058	Belongs to the CinA family
AL520_17300	COG2207	Transcriptional regulator
AL520_17305	COG1064	alcohol dehydrogenase
AL520_17320	COG3608	succinylglutamate desuccinylase aspartoacylase
AL520_17320	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AL520_17330	COG1850	ribulose-bisphosphate carboxylase activity
AL520_17340	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL520_17345	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL520_17350	COG1609	Transcriptional regulator
AL520_17365	COG0500	methyltransferase
AL520_17395	COG2814	Major facilitator Superfamily
AL520_17400	COG0583	DNA-binding transcription factor activity
AL520_17420	COG1737	Transcriptional regulator
AL520_17420	COG0837	glucose binding
AL520_17430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL520_17460	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_17470	COG0235	Class ii aldolase
AL520_17475	COG1396	sequence-specific DNA binding
AL520_17535	COG0811	peptide transport
AL520_17565	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL520_17580	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AL520_17585	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AL520_17590	COG1116	anion transmembrane transporter activity
AL520_17595	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL520_17600	COG1116	anion transmembrane transporter activity
AL520_17600	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL520_17605	COG2197	response regulator
AL520_17615	COG1131	(ABC) transporter
AL520_17620	COG0842	Transport permease protein
AL520_17635	COG0183	Belongs to the thiolase family
AL520_17665	COG0318	PFAM AMP-dependent synthetase and ligase
AL520_17675	COG0604	alcohol dehydrogenase
AL520_17675	COG3321	synthase
AL520_17720	COG1272	protein, Hemolysin III
AL520_17750	COG2169	Transcriptional regulator
AL520_17770	COG2837	iron assimilation
AL520_17825	COG1464	Belongs to the NlpA lipoprotein family
AL520_17830	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AL520_17835	COG2011	ABC-type metal ion transport system permease component
AL520_17870	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_17875	COG3618	amidohydrolase
AL520_17890	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
AL520_17895	COG3153	acetyltransferase
AL520_17905	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_17910	COG1473	amidohydrolase
AL520_17920	COG1309	transcriptional regulator
AL520_17925	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_17935	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AL520_17940	COG0583	DNA-binding transcription factor activity
AL520_17960	COG0519	Catalyzes the synthesis of GMP from XMP
AL520_17975	COG0519	Catalyzes the synthesis of GMP from XMP
AL520_18010	COG1522	sequence-specific DNA binding
AL520_18055	COG3386	PFAM SMP-30 Gluconolaconase
AL520_18080	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL520_18090	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_18120	COG0625	glutathione transferase activity
AL520_18135	COG3530	Putative quorum-sensing-regulated virulence factor
AL520_18145	COG2814	Major facilitator Superfamily
AL520_18180	COG0443	Heat shock 70 kDa protein
AL520_18185	COG0494	nUDIX hydrolase
AL520_18195	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL520_18200	COG0477	Major facilitator Superfamily
AL520_18210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL520_18220	COG0542	response to heat
AL520_18245	COG5441	Belongs to the UPF0261 family
AL520_18250	COG5564	TIM-barrel signal transduction protein
AL520_18265	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AL520_18280	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AL520_18290	COG1562	ergosterol biosynthetic process
AL520_18300	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AL520_18305	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_18315	COG3971	2-oxopent-4-enoate hydratase activity
AL520_18330	COG1012	belongs to the aldehyde dehydrogenase family
AL520_18335	COG3384	dioxygenase
AL520_18365	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL520_18375	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_18385	COG2186	Transcriptional regulator
AL520_18390	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AL520_18395	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_18405	COG0019	diaminopimelate decarboxylase activity
AL520_18410	COG0583	DNA-binding transcription factor activity
AL520_18415	COG0268	Binds directly to 16S ribosomal RNA
AL520_18425	COG0728	peptidoglycan biosynthetic process
AL520_18435	COG0563	adenylate kinase activity
AL520_18440	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AL520_18445	COG2835	tetraacyldisaccharide 4'-kinase activity
AL520_18455	COG1663	tetraacyldisaccharide 4'-kinase activity
AL520_18465	COG0811	peptide transport
AL520_18470	COG1570	exodeoxyribonuclease VII activity
AL520_18480	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AL520_18490	COG0038	chloride channel
AL520_18495	COG0183	Belongs to the thiolase family
AL520_18505	COG1278	Cold shock
AL520_18510	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AL520_18515	COG2373	Large extracellular alpha-helical protein
AL520_18530	COG2995	paraquat-inducible protein a
AL520_18535	COG3008	intermembrane lipid transfer
AL520_18545	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AL520_18545	COG0506	proline dehydrogenase activity
AL520_18545	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AL520_18555	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL520_18565	COG0411	ABC transporter
AL520_18575	COG2271	Major facilitator Superfamily
AL520_18595	COG1764	response to oxidative stress
AL520_18600	COG2423	ornithine cyclodeaminase activity
AL520_18610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL520_18615	COG0765	amino acid transport
AL520_18620	COG0765	amino acid transport
AL520_18625	COG1126	abc transporter atp-binding protein
AL520_18630	COG1902	pentaerythritol trinitrate reductase activity
AL520_18680	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AL520_18685	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AL520_18690	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AL520_18695	COG0196	riboflavin kinase activity
AL520_18700	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AL520_18705	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AL520_18705	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AL520_18720	COG0210	DNA helicase
AL520_18730	COG1858	cytochrome C peroxidase
AL520_18740	COG4771	TonB-dependent receptor
AL520_18745	COG4771	TonB-dependent receptor
AL520_18760	COG0488	(ABC) transporter
AL520_18765	COG2890	protein-(glutamine-N5) methyltransferase activity
AL520_18775	COG2171	N-acyltransferase activity
AL520_18810	COG2271	Major facilitator Superfamily
AL520_18820	COG0277	FAD linked oxidase domain protein
AL520_18830	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AL520_18845	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AL520_18885	COG0583	DNA-binding transcription factor activity
AL520_18895	COG0251	oxidation-reduction process
AL520_18920	COG1278	Cold shock
AL520_18930	COG1278	Cold shock
AL520_18940	COG0501	Belongs to the peptidase M48B family
AL520_18945	COG0544	peptidyl-prolyl cis-trans isomerase activity
AL520_18950	COG0740	serine-type endopeptidase activity
AL520_18955	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AL520_18960	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AL520_18965	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AL520_18975	COG0556	nucleotide-excision repair
AL520_18980	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AL520_18990	COG1104	cysteine desulfurase activity
AL520_18995	COG0822	iron-sulfur transferase activity
AL520_19000	COG0316	Belongs to the HesB IscA family
AL520_19005	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AL520_19010	COG0443	Heat shock 70 kDa protein
AL520_19015	COG0633	Ferredoxin
AL520_19020	COG2975	iron-sulfur cluster assembly
AL520_19025	COG1803	Methylglyoxal synthase
AL520_19035	COG1024	Enoyl-CoA hydratase
AL520_19060	COG0410	ABC transporter
AL520_19070	COG0183	Belongs to the thiolase family
AL520_19075	COG1309	transcriptional regulator
AL520_19080	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AL520_19085	COG3135	benzoate transporter
AL520_19100	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AL520_19105	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_19115	COG2271	Major facilitator Superfamily
AL520_19150	COG1136	(ABC) transporter
AL520_19155	COG0084	hydrolase, TatD family'
AL520_19165	COG0745	RESPONSE REGULATOR receiver
AL520_19170	COG4771	TonB-dependent receptor
AL520_19175	COG4607	ABC-type enterochelin transport system periplasmic component
AL520_19180	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL520_19185	COG4605	iron ion homeostasis
AL520_19190	COG4604	ABC transporter, ATP-binding protein
AL520_19205	COG1595	DNA-templated transcription, initiation
AL520_19235	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
AL520_19240	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_19280	COG0459	protein refolding
AL520_19285	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AL520_19295	COG2249	NAD(P)H dehydrogenase (quinone) activity
AL520_19320	COG3093	addiction module antidote protein HigA
AL520_19345	COG0159	tryptophan synthase activity
AL520_19360	COG0583	DNA-binding transcription factor activity
AL520_19370	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL520_19390	COG0613	PHP domain protein
AL520_19400	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL520_19405	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL520_19415	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AL520_19415	COG0047	phosphoribosylformylglycinamidine synthase activity
AL520_19435	COG0745	RESPONSE REGULATOR receiver
AL520_19465	COG0583	DNA-binding transcription factor activity
AL520_19485	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_19515	COG2198	Histidine kinase
AL520_19515	COG0784	Response regulator, receiver
AL520_19515	COG2205	protein histidine kinase activity
AL520_19515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL520_19540	COG1953	Uracil, thiamine, allantoin
AL520_19550	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AL520_19595	COG4774	siderophore transport
AL520_19600	COG5001	Diguanylate cyclase
AL520_19625	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL520_19640	COG3618	amidohydrolase
AL520_19655	COG1960	acyl-CoA dehydrogenase activity
AL520_19665	COG1024	Enoyl-CoA hydratase
AL520_19715	COG4774	siderophore transport
AL520_19755	COG0747	negative chemotaxis
AL520_19760	COG4608	Belongs to the ABC transporter superfamily
AL520_19770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL520_19775	COG0601	transmembrane transport
AL520_19780	COG2072	flavoprotein involved in K transport
AL520_19810	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_19815	COG3048	D-serine ammonia-lyase activity
AL520_19820	COG0583	DNA-binding transcription factor activity
AL520_19840	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL520_19850	COG0583	DNA-binding transcription factor activity
AL520_19880	COG0519	Catalyzes the synthesis of GMP from XMP
AL520_19880	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AL520_19895	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AL520_19930	COG2207	Transcriptional regulator
AL520_19950	COG0640	Transcriptional regulator
AL520_19970	COG1846	Transcriptional regulator
AL520_19990	COG2207	Transcriptional regulator
AL520_20010	COG2267	carboxylic ester hydrolase activity
AL520_20045	COG0583	DNA-binding transcription factor activity
AL520_20070	COG0477	Major facilitator Superfamily
AL520_20105	COG0456	acetyltransferase
AL520_20120	COG1199	ATP-dependent helicase activity
AL520_20135	COG0583	DNA-binding transcription factor activity
AL520_20145	COG0154	amidase activity
AL520_20150	COG0840	transmembrane signaling receptor activity
AL520_20180	COG5001	Diguanylate cyclase
AL520_20180	COG4251	negative regulation of phosphorylation
AL520_20180	COG2203	Gaf domain
AL520_20180	COG3706	GGDEF domain
AL520_20185	COG4149	molybdate abc transporter
AL520_20190	COG1840	ABC-type Fe3 transport system, periplasmic component
AL520_20195	COG3842	ATPase activity
AL520_20200	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL520_20205	COG1522	sequence-specific DNA binding
AL520_20220	COG2010	Cytochrome c
AL520_20220	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AL520_20225	COG1335	isochorismatase
AL520_20230	COG2309	aminopeptidase activity
AL520_20235	COG0596	Alpha beta hydrolase
AL520_20245	COG2010	Cytochrome c
AL520_20245	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AL520_20250	COG0477	Major facilitator Superfamily
AL520_20255	COG1846	Transcriptional regulator
AL520_20260	COG2814	Major facilitator Superfamily
AL520_20265	COG4771	TonB-dependent receptor
AL520_20280	COG0583	DNA-binding transcription factor activity
AL520_20295	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AL520_20305	COG0318	PFAM AMP-dependent synthetase and ligase
AL520_20310	COG1960	acyl-CoA dehydrogenase activity
AL520_20315	COG1960	acyl-CoA dehydrogenase activity
AL520_20320	COG0183	Belongs to the thiolase family
AL520_20325	COG1024	Enoyl-CoA hydratase
AL520_20325	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL520_20330	COG0583	DNA-binding transcription factor activity
AL520_20355	COG0148	phosphopyruvate hydratase activity
AL520_20365	COG2733	membrane
AL520_20370	COG2032	superoxide dismutase activity
AL520_20375	COG0625	glutathione transferase activity
AL520_20385	COG0024	Methionine aminopeptidase
AL520_20575	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
AL520_20585	COG2885	chlorophyll binding
AL520_20610	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL520_20630	COG3971	2-oxopent-4-enoate hydratase activity
AL520_20635	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL520_20655	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL520_20660	COG1414	Transcriptional regulator
AL520_20670	COG3541	Predicted nucleotidyltransferase
AL520_20675	COG1846	Transcriptional regulator
AL520_20695	COG0456	acetyltransferase
AL520_20705	COG0583	DNA-binding transcription factor activity
AL520_20715	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL520_20725	COG0697	spore germination
AL520_20735	COG4941	Belongs to the sigma-70 factor family
AL520_20745	COG3795	YCII-related domain
AL520_20750	COG2885	chlorophyll binding
AL520_20750	COG3047	cAMP biosynthetic process
AL520_20780	COG1683	Conserved Protein
AL520_20800	COG1309	transcriptional regulator
AL520_20805	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_20815	COG0667	Aldo Keto reductase
AL520_20820	COG0477	Major facilitator Superfamily
AL520_20830	COG1414	Transcriptional regulator
AL520_20840	COG2345	Transcriptional regulator
AL520_20845	COG4774	siderophore transport
AL520_20865	COG2764	glyoxalase bleomycin resistance protein dioxygenase
AL520_20925	COG3328	transposase activity
AL520_20940	COG0840	transmembrane signaling receptor activity
AL520_20950	COG3038	cytochrome b561
AL520_20955	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL520_20960	COG1309	transcriptional regulator
AL520_20975	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AL520_20985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL520_20990	COG0765	amino acid transport
AL520_20995	COG0765	amino acid transport
AL520_21025	COG0667	Aldo Keto reductase
AL520_21035	COG0789	Transcriptional regulator
AL520_21045	COG0587	DNA-directed DNA polymerase activity
AL520_21065	COG0833	amino acid
AL520_21070	COG0400	carboxylic ester hydrolase activity
AL520_21080	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_21090	COG0028	Belongs to the TPP enzyme family
AL520_21105	COG1566	PFAM secretion protein HlyD family protein
AL520_21115	COG1289	transmembrane transporter activity
AL520_21125	COG0720	synthase
AL520_21130	COG0602	queuosine metabolic process
AL520_21145	COG1902	pentaerythritol trinitrate reductase activity
AL520_21175	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AL520_21190	COG0842	Transport permease protein
AL520_21195	COG1131	(ABC) transporter
AL520_21210	COG2130	NADP-dependent
AL520_21235	COG3842	ATPase activity
AL520_21240	COG3842	ATPase activity
AL520_21250	COG0395	ABC-type sugar transport system, permease component
AL520_21285	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL520_21310	COG3634	alkyl hydroperoxide reductase activity
AL520_21315	COG1959	2 iron, 2 sulfur cluster binding
AL520_21325	COG0583	DNA-binding transcription factor activity
AL520_21330	COG1960	acyl-CoA dehydrogenase activity
AL520_21365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL520_21370	COG0420	3'-5' exonuclease activity
AL520_21395	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AL520_21395	COG2111	Na H antiporter
AL520_21400	COG1006	Multisubunit Na H antiporter MnhC subunit
AL520_21405	COG0651	ATP synthesis coupled electron transport
AL520_21410	COG1863	multisubunit Na H antiporter MnhE subunit
AL520_21415	COG2212	antiporter activity
AL520_21420	COG1320	monovalent cation:proton antiporter activity
AL520_21435	COG0590	tRNA wobble adenosine to inosine editing
AL520_21440	COG1619	proteins homologs of microcin C7 resistance protein MccF
AL520_21445	COG0488	(ABC) transporter
AL520_21450	COG2814	Major facilitator Superfamily
AL520_21455	COG1116	anion transmembrane transporter activity
AL520_21480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL520_21485	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL520_21495	COG2252	PERMEase
AL520_21500	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AL520_21505	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AL520_21510	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AL520_21515	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AL520_21540	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AL520_21545	COG0789	Transcriptional regulator
AL520_21560	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AL520_21560	COG0678	peroxiredoxin activity
AL520_21570	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AL520_21575	COG0584	glycerophosphoryl diester phosphodiesterase
AL520_21585	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL520_21595	COG4181	ATPase activity
AL520_21605	COG1178	ABC-type Fe3 transport system permease component
AL520_21610	COG3842	ATPase activity
AL520_21615	COG0583	DNA-binding transcription factor activity
AL520_21620	COG0560	Phosphoserine phosphatase
AL520_21635	COG0583	DNA-binding transcription factor activity
AL520_21650	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL520_21665	COG0583	DNA-binding transcription factor activity
AL520_21670	COG4336	lyase activity
AL520_21680	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL520_21690	COG0411	ABC transporter
AL520_21695	COG0410	ABC transporter
AL520_21700	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL520_21720	COG2816	NAD+ diphosphatase activity
AL520_21740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL520_21745	COG0765	amino acid transport
AL520_21750	COG1126	abc transporter atp-binding protein
AL520_21755	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL520_21760	COG1758	RNA polymerase activity
AL520_21765	COG0194	GDP metabolic process
AL520_21770	COG3258	Cytochrome c
AL520_21775	COG2863	cytochrome
AL520_21780	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_21785	COG2831	hemolysin activation secretion protein
AL520_21815	COG0791	NLP P60 protein
AL520_21830	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AL520_21835	COG0833	amino acid
AL520_21840	COG1561	YicC-like family, N-terminal region
AL520_21845	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AL520_21855	COG1960	acyl-CoA dehydrogenase activity
AL520_21865	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AL520_21870	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AL520_21880	COG3852	Histidine kinase
AL520_21885	COG2204	response regulator
AL520_21890	COG0583	DNA-binding transcription factor activity
AL520_21895	COG1741	Belongs to the pirin family
AL520_21900	COG1741	Belongs to the pirin family
AL520_21905	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AL520_21910	COG1690	Belongs to the RtcB family
AL520_21920	COG3842	ATPase activity
AL520_21925	COG4149	molybdate abc transporter
AL520_21930	COG1840	ABC-type Fe3 transport system, periplasmic component
AL520_21940	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_21955	COG0583	DNA-binding transcription factor activity
AL520_21975	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AL520_21985	COG0783	Belongs to the Dps family
AL520_21995	COG0457	Tetratricopeptide repeat
AL520_22000	COG0438	transferase activity, transferring glycosyl groups
AL520_22025	COG4783	chaperone-mediated protein folding
AL520_22025	COG1560	Kdo2-lipid A biosynthetic process
AL520_22030	COG3866	Pectate lyase
AL520_22045	COG0745	RESPONSE REGULATOR receiver
AL520_22050	COG2205	protein histidine kinase activity
AL520_22065	COG3842	ATPase activity
AL520_22070	COG0395	ABC-type sugar transport system, permease component
AL520_22075	COG1175	transmembrane transport
AL520_22080	COG1653	transport
AL520_22090	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AL520_22100	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL520_22115	COG0410	ABC transporter
AL520_22130	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AL520_22140	COG0583	DNA-binding transcription factor activity
AL520_22145	COG0625	glutathione transferase activity
AL520_22150	COG2133	pyrroloquinoline quinone binding
AL520_22160	COG0697	spore germination
AL520_22165	COG2363	Small membrane protein
AL520_22185	COG0010	Belongs to the arginase family
AL520_22190	COG1464	Belongs to the NlpA lipoprotein family
AL520_22195	COG3706	GGDEF domain
AL520_22200	COG2814	Major facilitator Superfamily
AL520_22210	COG1408	metallophosphoesterase
AL520_22245	COG0688	phosphatidylethanolamine metabolic process
AL520_22255	COG0488	(ABC) transporter
AL520_22280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL520_22285	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL520_22290	COG5001	Diguanylate cyclase
AL520_22290	COG3300	MHYT domain
AL520_22305	COG2814	Major facilitator Superfamily
AL520_22325	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AL520_22330	COG2204	response regulator
AL520_22365	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_22380	COG0693	protein deglycase activity
AL520_22390	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL520_22400	COG1289	transmembrane transporter activity
AL520_22405	COG5001	Diguanylate cyclase
AL520_22405	COG3300	MHYT domain
AL520_22435	COG3415	Transposase
AL520_22435	COG2801	Transposase and inactivated derivatives
AL520_22455	COG1253	flavin adenine dinucleotide binding
AL520_22470	COG2205	protein histidine kinase activity
AL520_22525	COG3706	GGDEF domain
AL520_22530	COG0789	Transcriptional regulator
AL520_22540	COG3706	GGDEF domain
AL520_22600	COG0628	permease
AL520_22625	COG0531	amino acid
AL520_22635	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AL520_22640	COG4608	Belongs to the ABC transporter superfamily
AL520_22645	COG0444	Belongs to the ABC transporter superfamily
AL520_22650	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL520_22655	COG0601	transmembrane transport
AL520_22660	COG0747	negative chemotaxis
AL520_22690	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL520_22705	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AL520_22715	COG2146	nitrite reductase [NAD(P)H] activity
AL520_22730	COG3971	2-oxopent-4-enoate hydratase activity
AL520_22760	COG0625	glutathione transferase activity
AL520_22775	COG0477	Major facilitator Superfamily
AL520_22785	COG0579	oxidoreductase
AL520_22810	COG1280	lysine exporter protein (LysE YggA)
AL520_22840	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL520_22845	COG0589	response to stress
AL520_22855	COG0589	response to stress
AL520_22865	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AL520_22890	COG0668	transmembrane transport
AL520_22900	COG0166	Belongs to the GPI family
AL520_22915	COG3685	Protein conserved in bacteria
AL520_22930	COG0387	Pfam Sodium calcium exchanger
AL520_22935	COG3568	Endonuclease Exonuclease Phosphatase
AL520_22940	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL520_22945	COG0392	lysyltransferase activity
AL520_22950	COG0297	glycogen (starch) synthase activity
AL520_22955	COG0366	Alpha amylase catalytic
AL520_22960	COG0366	Alpha amylase catalytic
AL520_22965	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AL520_22975	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AL520_22980	COG1640	4-alpha-glucanotransferase
AL520_22990	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AL520_23020	COG4771	TonB-dependent receptor
AL520_23030	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AL520_23035	COG1595	DNA-templated transcription, initiation
AL520_23045	COG4774	siderophore transport
AL520_23065	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL520_23070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL520_23085	COG0519	Catalyzes the synthesis of GMP from XMP
AL520_23085	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AL520_23095	COG1276	copper resistance
AL520_23110	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_23115	COG2721	sulfolactate sulfo-lyase activity
AL520_23140	COG0745	RESPONSE REGULATOR receiver
AL520_23150	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL520_23155	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
AL520_23160	COG1120	ATPase activity
AL520_23165	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AL520_23180	COG0586	Pfam SNARE associated Golgi protein
AL520_23185	COG0390	transport system, permease component
AL520_23190	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AL520_23235	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL520_23240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL520_23245	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL520_23250	COG1120	ATPase activity
AL520_23260	COG0765	amino acid transport
AL520_23270	COG2070	2-Nitropropane dioxygenase
AL520_23275	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL520_23285	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL520_23315	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AL520_23320	COG0583	DNA-binding transcription factor activity
AL520_23340	COG4566	intracellular signal transduction
AL520_23365	COG4774	siderophore transport
AL520_23405	COG0583	DNA-binding transcription factor activity
AL520_23435	COG0765	amino acid transport
AL520_23445	COG0277	FAD linked oxidase domain protein
AL520_23470	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AL520_23495	COG0251	oxidation-reduction process
AL520_23530	COG4948	Mandelate Racemase Muconate Lactonizing
AL520_23540	COG1802	Transcriptional regulator
AL520_23545	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL520_23560	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AL520_23590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL520_23595	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL520_23600	COG1116	anion transmembrane transporter activity
AL520_23635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL520_23640	COG4597	amino acid ABC transporter
AL520_23660	COG2197	response regulator
AL520_23665	COG3850	Histidine kinase
AL520_23670	COG1763	Mo-molybdopterin cofactor biosynthetic process
AL520_23675	COG0288	reversible hydration of carbon dioxide
AL520_23680	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AL520_23685	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL520_23690	COG2181	nitrate reductase activity
AL520_23695	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AL520_23700	COG1140	nitrate reductase beta subunit
AL520_23705	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AL520_23710	COG2223	nitrite transmembrane transporter activity
AL520_23730	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL520_23735	COG0583	DNA-binding transcription factor activity
AL520_23745	COG0583	DNA-binding transcription factor activity
AL520_23755	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_23785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL520_23805	COG2070	2-Nitropropane dioxygenase
AL520_23810	COG5002	protein histidine kinase activity
AL520_23815	COG0745	RESPONSE REGULATOR receiver
AL520_23820	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
AL520_23825	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AL520_23835	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL520_23840	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL520_23855	COG0783	Belongs to the Dps family
AL520_23885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL520_23890	COG0697	spore germination
AL520_23895	COG2879	small protein
AL520_23900	COG1966	Carbon starvation protein
AL520_23920	COG0697	spore germination
AL520_23925	COG0583	DNA-binding transcription factor activity
AL520_23930	COG3415	Transposase
AL520_23930	COG2801	Transposase and inactivated derivatives
AL520_23935	COG4521	taurine ABC transporter
AL520_23940	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AL520_23945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL520_23965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL520_23975	COG0523	cobalamin synthesis protein
AL520_23980	COG1228	amidohydrolase
AL520_23985	COG4172	Belongs to the ABC transporter superfamily
AL520_23990	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL520_23995	COG0601	transmembrane transport
AL520_24000	COG0747	negative chemotaxis
AL520_24015	COG1414	Transcriptional regulator
AL520_24020	COG0513	Belongs to the DEAD box helicase family
AL520_24040	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL520_24050	COG0840	transmembrane signaling receptor activity
AL520_24060	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AL520_24090	COG2814	Major facilitator Superfamily
AL520_24095	COG0386	Belongs to the glutathione peroxidase family
AL520_24100	COG1522	sequence-specific DNA binding
AL520_24110	COG0625	glutathione transferase activity
AL520_24125	COG0095	Lipoate-protein ligase
AL520_24135	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AL520_24145	COG0010	Belongs to the arginase family
AL520_24150	COG1126	abc transporter atp-binding protein
AL520_24160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL520_24175	COG0084	hydrolase, TatD family'
AL520_24180	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AL520_24185	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AL520_24215	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL520_24215	COG1024	Enoyl-CoA hydratase
AL520_24225	COG2914	Belongs to the UPF0125 (RnfH) family
AL520_24230	COG2867	negative regulation of translational initiation
AL520_24235	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AL520_24240	COG0745	RESPONSE REGULATOR receiver
AL520_24240	COG3706	GGDEF domain
AL520_24255	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AL520_24255	COG0519	Catalyzes the synthesis of GMP from XMP
AL520_24260	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AL520_24260	COG2169	Transcriptional regulator
AL520_24270	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AL520_24300	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL520_24305	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AL520_24310	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL520_24320	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AL520_24325	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL520_24330	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AL520_24335	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL520_24340	COG0750	zinc metalloprotease
AL520_24345	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AL520_24355	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AL520_24360	COG0233	cytoplasmic translational termination
AL520_24365	COG0528	UMP kinase activity
AL520_24370	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AL520_24375	COG0052	Belongs to the universal ribosomal protein uS2 family
AL520_24380	COG0024	Methionine aminopeptidase
AL520_24385	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AL520_24395	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AL520_24410	COG1451	nucleotide metabolic process
AL520_24420	COG1286	toxin biosynthetic process
AL520_24430	COG0285	dihydrofolate synthase activity
AL520_24440	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_24445	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL520_24455	COG1414	Transcriptional regulator
AL520_24465	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AL520_24485	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AL520_24495	COG1677	Flagellar hook-basal body complex protein FliE
AL520_24500	COG1766	The M ring may be actively involved in energy transduction
AL520_24505	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AL520_24530	COG1580	Controls the rotational direction of flagella during chemotaxis
AL520_24540	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AL520_24565	COG0840	transmembrane signaling receptor activity
AL520_24570	COG0840	transmembrane signaling receptor activity
AL520_24580	COG0840	transmembrane signaling receptor activity
AL520_24585	COG0840	transmembrane signaling receptor activity
AL520_24595	COG1256	bacterial-type flagellum assembly
AL520_24605	COG1706	bacterial-type flagellum-dependent cell motility
AL520_24610	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AL520_24615	COG4786	Flagellar basal body rod
AL520_24620	COG4787	bacterial-type flagellum-dependent cell motility
AL520_24625	COG1749	Flagellar hook protein flgE
AL520_24630	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AL520_24635	COG1558	bacterial-type flagellum-dependent cell motility
AL520_24650	COG2747	anti-sigma28 factor FlgM
AL520_24680	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AL520_24685	COG0745	RESPONSE REGULATOR receiver
AL520_24690	COG2201	protein-glutamate methylesterase activity
AL520_24695	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AL520_24700	COG0840	transmembrane signaling receptor activity
AL520_24705	COG0835	chemotaxis
AL520_24740	COG1191	sigma factor activity
AL520_24745	COG4797	methyltransferase
AL520_24745	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL520_24775	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL520_24780	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL520_24785	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AL520_24795	COG4566	intracellular signal transduction
AL520_24805	COG0339	signal peptide processing
AL520_24815	COG1999	signal sequence binding
AL520_24820	COG2261	transglycosylase associated protein
AL520_24825	COG1538	Outer membrane efflux protein
AL520_24840	COG0583	DNA-binding transcription factor activity
AL520_24845	COG1187	pseudouridine synthase activity
AL520_24850	COG3161	chorismate lyase activity
AL520_24855	COG0477	Major facilitator Superfamily
AL520_24875	COG4681	YaeQ
AL520_24880	COG4172	Belongs to the ABC transporter superfamily
AL520_24890	COG0601	transmembrane transport
AL520_24895	COG0747	negative chemotaxis
AL520_24905	COG0583	DNA-binding transcription factor activity
AL520_24940	COG2165	general secretion pathway protein
AL520_25020	COG0668	transmembrane transport
AL520_25025	COG0165	Argininosuccinate lyase
AL520_25045	COG0022	dehydrogenase e1 component
AL520_25055	COG4774	siderophore transport
AL520_25080	COG0789	Transcriptional regulator
AL520_25090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL520_25100	COG2271	Major facilitator Superfamily
AL520_25110	COG0307	riboflavin synthase, alpha
AL520_25120	COG2186	Transcriptional regulator
AL520_25125	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_25205	COG2070	2-Nitropropane dioxygenase
AL520_25265	COG0154	amidase activity
AL520_25270	COG2814	Major facilitator Superfamily
AL520_25295	COG2814	Major facilitator Superfamily
AL520_25310	COG0583	DNA-binding transcription factor activity
AL520_25325	COG0583	DNA-binding transcription factor activity
AL520_25350	COG2059	Chromate
AL520_25405	COG5265	(ABC) transporter
AL520_25450	COG0318	PFAM AMP-dependent synthetase and ligase
AL520_25470	COG0477	Major facilitator Superfamily
AL520_25475	COG0235	Class ii aldolase
AL520_25520	COG2610	gluconate transmembrane transporter activity
AL520_25525	COG0583	DNA-binding transcription factor activity
AL520_25530	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_25535	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
AL520_25550	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL520_25575	COG1024	Enoyl-CoA hydratase
AL520_25580	COG5001	Diguanylate cyclase
AL520_25585	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_25590	COG0129	dihydroxy-acid dehydratase activity
AL520_25600	COG0583	DNA-binding transcription factor activity
AL520_25605	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL520_25610	COG3246	L-lysine catabolic process to acetate
AL520_25630	COG3381	protein complex oligomerization
AL520_25650	COG4133	protoheme IX ABC transporter activity
AL520_25655	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL520_25670	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AL520_25680	COG3088	subunit of a heme lyase
AL520_25700	COG5002	protein histidine kinase activity
AL520_25700	COG5001	Diguanylate cyclase
AL520_25700	COG3447	MASE1 domain protein
AL520_25705	COG0583	DNA-binding transcription factor activity
AL520_25730	COG4172	Belongs to the ABC transporter superfamily
AL520_25740	COG0583	DNA-binding transcription factor activity
AL520_25745	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_25750	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_25765	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL520_25775	COG1063	alcohol dehydrogenase
AL520_25800	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AL520_25805	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL520_25810	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_25815	COG2207	Transcriptional regulator
AL520_25850	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_25860	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AL520_25865	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL520_25875	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_25880	COG1024	Enoyl-CoA hydratase
AL520_25885	COG0534	Mate efflux family protein
AL520_25900	COG0697	spore germination
AL520_25905	COG0697	spore germination
AL520_25920	COG1280	lysine exporter protein (LysE YggA)
AL520_25935	COG1280	lysine exporter protein (LysE YggA)
AL520_25940	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AL520_25960	COG0318	PFAM AMP-dependent synthetase and ligase
AL520_25965	COG1960	acyl-CoA dehydrogenase activity
AL520_25985	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AL520_25990	COG2814	Major facilitator Superfamily
AL520_26005	COG0625	glutathione transferase activity
AL520_26020	COG2814	Major facilitator Superfamily
AL520_26025	COG0583	DNA-binding transcription factor activity
AL520_26045	COG0506	proline dehydrogenase activity
AL520_26050	COG0697	spore germination
AL520_26060	COG1959	2 iron, 2 sulfur cluster binding
AL520_26065	COG1017	nitric oxide dioxygenase activity
AL520_26065	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL520_26085	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL520_26090	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL520_26100	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AL520_26135	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL520_26145	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_26150	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL520_26160	COG1610	YqeY-like protein
AL520_26200	COG0457	Tetratricopeptide repeat
AL520_26205	COG0726	polysaccharide deacetylase
AL520_26205	COG1649	PFAM Uncharacterised BCR, COG1649
AL520_26210	COG1215	transferase activity, transferring glycosyl groups
AL520_26220	COG2223	nitrite transmembrane transporter activity
AL520_26225	COG4977	sequence-specific DNA binding
AL520_26225	COG1917	Cupin 2, conserved barrel domain protein
AL520_26235	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AL520_26250	COG0656	L-ascorbic acid biosynthetic process
AL520_26255	COG5265	(ABC) transporter
AL520_26285	COG1116	anion transmembrane transporter activity
AL520_26310	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_26315	COG0583	DNA-binding transcription factor activity
AL520_26345	COG1522	sequence-specific DNA binding
AL520_26395	COG0384	phenazine biosynthesis protein PhzF
AL520_26430	COG0776	regulation of translation
AL520_26435	COG0072	phenylalanine-tRNA ligase activity
AL520_26435	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL520_26440	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AL520_26445	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AL520_26450	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AL520_26460	COG2960	long-chain fatty acid transporting porin activity
AL520_26470	COG0347	Belongs to the P(II) protein family
AL520_26475	COG0004	ammonium transporteR
AL520_26480	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AL520_26485	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL520_26495	COG0189	ligase activity
AL520_26505	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AL520_26515	COG2197	response regulator
AL520_26520	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AL520_26550	COG1012	belongs to the aldehyde dehydrogenase family
AL520_26560	COG0601	transmembrane transport
AL520_26565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL520_26590	COG1609	Transcriptional regulator
AL520_26595	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AL520_26600	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL520_26605	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL520_26610	COG0129	dihydroxy-acid dehydratase activity
AL520_26615	COG2755	lipolytic protein G-D-S-L family
AL520_26615	COG0657	acetylesterase activity
AL520_26660	COG0135	phosphoribosylanthranilate isomerase activity
AL520_26665	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AL520_26670	COG0101	tRNA pseudouridine synthase activity
AL520_26680	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AL520_26685	COG0473	3-isopropylmalate dehydrogenase activity
AL520_26690	COG0066	3-isopropylmalate dehydratase activity
AL520_26695	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AL520_26710	COG2274	protein secretion by the type I secretion system
AL520_26715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL520_26750	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AL520_26760	COG3706	GGDEF domain
AL520_26775	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AL520_26785	COG1295	ribonuclease BN
AL520_26795	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AL520_26825	COG4964	Belongs to the GSP D family
AL520_26855	COG2755	lipolytic protein G-D-S-L family
AL520_26855	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AL520_26870	COG0438	transferase activity, transferring glycosyl groups
AL520_27040	COG5410	chromosome segregation
AL520_27055	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AL520_27060	COG1121	(ABC) transporter
AL520_27075	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
AL520_27160	COG0419	ATPase involved in DNA repair
AL520_27200	COG0697	spore germination
AL520_27315	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AL520_27355	COG3909	cytochrome
AL520_27365	COG0625	glutathione transferase activity
AL520_27370	COG0730	response to heat
AL520_27375	COG0482	sulfurtransferase activity
AL520_27380	COG0583	DNA-binding transcription factor activity
AL520_27395	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AL520_27400	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AL520_27405	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AL520_27410	COG0247	lactate metabolic process
AL520_27415	COG0277	FAD linked oxidase domain protein
AL520_27420	COG0277	FAD linked oxidase domain protein
AL520_27425	COG0277	FAD linked oxidase domain protein
AL520_27430	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL520_27435	COG0312	modulator of DNA gyrase
AL520_27450	COG0308	aminopeptidase N
AL520_27455	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AL520_27475	COG0436	Aminotransferase
AL520_27485	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AL520_27490	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AL520_27505	COG0559	Belongs to the binding-protein-dependent transport system permease family
AL520_27515	COG0411	ABC transporter
AL520_27520	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_27535	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_27545	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AL520_27565	COG0181	hydroxymethylbilane synthase activity
AL520_27570	COG0861	Integral membrane protein TerC family
AL520_27575	COG0861	Integral membrane protein TerC family
AL520_27580	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AL520_27585	COG0045	succinate-CoA ligase (ADP-forming) activity
AL520_27600	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AL520_27605	COG0583	DNA-binding transcription factor activity
AL520_27610	COG2137	regulation of response to DNA damage stimulus
AL520_27615	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AL520_27625	COG0642	Histidine kinase
AL520_27650	COG0540	Belongs to the ATCase OTCase family
AL520_27680	COG0493	'glutamate synthase
AL520_27700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL520_27735	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AL520_27755	COG0305	Participates in initiation and elongation during chromosome replication
AL520_27765	COG0359	binds to the 23S rRNA
AL520_27770	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AL520_27775	COG2965	DNA replication, synthesis of RNA primer
AL520_27780	COG0360	Binds together with S18 to 16S ribosomal RNA
AL520_27785	COG3739	integral membrane protein
AL520_27790	COG1469	GTP cyclohydrolase I activity
AL520_27795	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AL520_27800	COG0142	geranyltranstransferase activity
AL520_27805	COG1722	exodeoxyribonuclease VII activity
AL520_27815	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_27835	COG1840	ABC-type Fe3 transport system, periplasmic component
AL520_27840	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL520_27850	COG3842	ATPase activity
AL520_27855	COG0583	DNA-binding transcription factor activity
AL520_27875	COG0501	Belongs to the peptidase M48B family
AL520_27880	COG1760	l-serine dehydratase
AL520_27885	COG1283	sodium-dependent phosphate transmembrane transporter activity
AL520_27890	COG3415	Transposase
AL520_27890	COG2801	Transposase and inactivated derivatives
AL520_27895	COG3328	transposase activity
AL520_27900	COG0412	Dienelactone hydrolase
AL520_27910	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AL520_27910	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AL520_27915	COG1611	Belongs to the LOG family
AL520_27920	COG1473	amidohydrolase
AL520_27925	COG3181	Tripartite tricarboxylate transporter family receptor
AL520_27950	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AL520_27955	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AL520_27960	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AL520_27965	COG2251	uridine kinase activity
AL520_27965	COG0195	Participates in both transcription termination and antitermination
AL520_27970	COG0779	Required for maturation of 30S ribosomal subunits
AL520_27975	COG1187	pseudouridine synthase activity
AL520_27980	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AL520_27990	COG0583	DNA-binding transcription factor activity
AL520_27995	COG0523	cobalamin synthesis protein
AL520_28000	COG0523	cobalamin synthesis protein
AL520_28015	COG0745	RESPONSE REGULATOR receiver
AL520_28025	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL520_28030	COG0625	glutathione transferase activity
AL520_28045	COG2003	Belongs to the UPF0758 family
AL520_28050	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AL520_28055	COG3483	tryptophan 2,3-dioxygenase activity
AL520_28060	COG0254	rRNA binding
AL520_28070	COG0534	Mate efflux family protein
AL520_28080	COG2050	protein possibly involved in aromatic compounds catabolism
AL520_28085	COG1024	Enoyl-CoA hydratase
AL520_28090	COG1012	belongs to the aldehyde dehydrogenase family
AL520_28095	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL520_28100	COG2151	metal-sulfur cluster biosynthetic enzyme
AL520_28105	COG3396	Phenylacetate-CoA oxygenase
AL520_28110	COG3460	Phenylacetate-CoA oxygenase
AL520_28115	COG3396	Phenylacetate-CoA oxygenase
AL520_28120	COG3327	negative regulation of DNA-templated transcription, initiation
AL520_28125	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AL520_28130	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AL520_28135	COG0501	Belongs to the peptidase M48B family
AL520_28140	COG1162	GTPase activity
AL520_28150	COG0335	large ribosomal subunit rRNA binding
AL520_28180	COG0175	sulfate reduction
AL520_28190	COG4208	sulfate ABC transporter
AL520_28195	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AL520_28205	COG0450	alkyl hydroperoxide reductase
AL520_28210	COG1960	acyl-CoA dehydrogenase activity
AL520_28215	COG2985	domain, Protein
AL520_28240	COG0123	including yeast histone deacetylase and acetoin utilization protein
AL520_28245	COG2951	lytic endotransglycosylase activity
AL520_28270	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL520_28275	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AL520_28280	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AL520_28300	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AL520_28305	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AL520_28325	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AL520_28340	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL520_28350	COG2814	Major facilitator Superfamily
AL520_28365	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AL520_28375	COG1215	transferase activity, transferring glycosyl groups
AL520_28395	COG1696	Membrane protein involved in D-alanine export
AL520_28405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AL520_28415	COG1960	acyl-CoA dehydrogenase activity
AL520_28430	COG2951	lytic endotransglycosylase activity
AL520_28435	COG2258	MOSC domain
AL520_28440	COG2833	Protein of unknown function (DUF455)
AL520_28455	COG1132	(ABC) transporter
AL520_28460	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AL520_28460	COG0189	ligase activity
AL520_28465	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AL520_28465	COG0189	ligase activity
AL520_28470	COG3237	CsbD-like
AL520_28475	COG2823	Periplasmic or secreted lipoprotein
AL520_28495	COG2831	hemolysin activation secretion protein
AL520_28520	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
AL520_28525	COG1028	Short-chain dehydrogenase reductase Sdr
AL520_28530	COG3243	poly(R)-hydroxyalkanoic acid synthase
AL520_28540	COG0564	pseudouridine synthase activity
AL520_28550	COG1199	ATP-dependent helicase activity
AL520_28555	COG2183	response to ionizing radiation
AL520_28565	COG0180	Tryptophanyl-tRNA synthetase
AL520_28590	COG4774	siderophore transport
AL520_28595	COG3712	iron ion homeostasis
AL520_28600	COG1595	DNA-templated transcription, initiation
AL520_28605	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AL520_28610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL520_28615	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL520_28620	COG0567	Dehydrogenase, E1 component
AL520_28625	COG1522	sequence-specific DNA binding
AL520_28630	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AL520_28645	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL520_28650	COG1297	OPT oligopeptide transporter protein
AL520_28660	COG0281	malic enzyme
AL520_28660	COG0280	phosphate acetyltransferase
AL520_28675	COG0372	Belongs to the citrate synthase family
AL520_28680	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AL520_28685	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AL520_28690	COG1053	succinate dehydrogenase
AL520_28695	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AL520_28700	COG2009	succinate dehydrogenase
AL520_28705	COG2188	Transcriptional regulator
AL520_28710	COG0039	L-malate dehydrogenase activity
AL520_28770	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL520_28780	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AL520_28790	COG0148	phosphopyruvate hydratase activity
AL520_28800	COG0504	CTP synthase activity
AL520_28825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL520_28835	COG0747	negative chemotaxis
AL520_28840	COG4172	Belongs to the ABC transporter superfamily
AL520_28845	COG1446	asparaginase
AL520_28855	COG2153	protein acetylation
AL520_28895	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AL520_28900	COG0697	spore germination
AL520_28915	COG3193	protein, possibly involved in utilization of glycolate and propanediol
AL520_28920	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL520_28925	COG0791	NLP P60 protein
AL520_28935	COG0583	DNA-binding transcription factor activity
AL520_28960	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AL520_28980	COG0667	Aldo Keto reductase
AL520_29000	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AL520_29010	COG1381	Involved in DNA repair and RecF pathway recombination
AL520_29015	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AL520_29020	COG0571	ribonuclease III activity
AL520_29025	COG0681	Belongs to the peptidase S26 family
AL520_29030	COG0481	GTPase activity
AL520_29035	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL520_29060	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL520_29065	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL520_29075	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AL520_29080	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL520_29085	COG0416	fatty acid biosynthetic process
AL520_29090	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AL520_29095	COG1399	metal-binding, possibly nucleic acid-binding protein
AL520_29100	COG0424	maF-like protein
AL520_29110	COG3023	N-Acetylmuramoyl-L-alanine amidase
AL520_29115	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AL520_29120	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AL520_29125	COG0546	phosphoglycolate phosphatase activity
AL520_29130	COG0564	pseudouridine synthase activity
AL520_29135	COG1530	ribonuclease E activity
AL520_29140	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AL520_29145	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AL520_29150	COG0159	tryptophan synthase activity
AL520_29155	COG0133	tryptophan synthase activity
AL520_29160	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL520_29170	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL520_29175	COG3228	Belongs to the MtfA family
AL520_29185	COG0251	oxidation-reduction process
AL520_29190	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AL520_29195	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AL520_29210	COG2878	Part of a membrane complex involved in electron transport
AL520_29215	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AL520_29220	COG0411	ABC transporter
AL520_29270	COG0411	ABC transporter
AL520_29285	COG1268	BioY protein
AL520_29290	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AL520_29295	COG1122	ATPase activity
AL520_29300	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL520_29305	COG2917	probably involved in intracellular septation
AL520_29315	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL520_29320	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AL520_29330	COG1196	nuclear chromosome segregation
AL520_29335	COG0477	Major facilitator Superfamily
AL520_29340	COG1573	uracil-dna glycosylase
AL520_29345	COG1214	PFAM Peptidase M22, glycoprotease
AL520_29350	COG0745	RESPONSE REGULATOR receiver
AL520_29355	COG2205	protein histidine kinase activity
AL520_29360	COG0450	alkyl hydroperoxide reductase
AL520_29365	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL520_29375	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AL520_29380	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AL520_29385	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AL520_29390	COG0560	Phosphoserine phosphatase
AL520_29405	COG4774	siderophore transport
AL520_29415	COG1007	ATP synthesis coupled electron transport
AL520_29430	COG0713	ATP synthesis coupled electron transport
AL520_29440	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL520_29445	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AL520_29450	COG1034	ATP synthesis coupled electron transport
AL520_29460	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AL520_29465	COG0649	NAD binding
AL520_29470	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL520_29475	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL520_29480	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL520_29485	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL520_29510	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AL520_29530	COG0583	DNA-binding transcription factor activity
AL520_29540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL520_29545	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL520_29565	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL520_29570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL520_29575	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL520_29590	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL520_29630	COG0747	negative chemotaxis
AL520_29775	COG0300	oxidoreductase activity
AL520_29780	COG0583	DNA-binding transcription factor activity
AL520_29790	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL520_29875	COG0802	atpase or kinase
AL520_29900	COG0583	DNA-binding transcription factor activity
AL520_29930	COG0456	acetyltransferase
AL520_29945	COG0765	amino acid transport
AL520_30015	COG0698	ribose 5-phosphate isomerase
AL520_30020	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AL520_30025	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AL520_30030	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL520_30090	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AL520_30090	COG2755	lipolytic protein G-D-S-L family
AL520_30230	COG1917	Cupin 2, conserved barrel domain protein
AL520_30235	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AL520_30270	COG1686	Belongs to the peptidase S11 family
AL520_30295	COG1074	ATP-dependent DNA helicase activity
AL520_30300	COG2814	Major facilitator Superfamily
AL520_30360	COG2814	Major facilitator Superfamily
AL520_30385	COG0642	Histidine kinase
AL520_30420	COG3706	GGDEF domain
AL520_30500	COG0583	DNA-binding transcription factor activity
AL520_30520	COG1204	response to ionizing radiation
AL520_30555	COG2080	2 iron, 2 sulfur cluster binding
AL520_30580	COG3501	Rhs element vgr protein
AL520_30595	COG3795	YCII-related domain
AL520_30600	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AL520_30610	COG3210	domain, Protein
AL520_30675	COG4774	siderophore transport
AL520_30720	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL520_30735	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL520_30755	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AL520_30930	COG3316	Transposase and inactivated derivatives