locus-tag	class	description
IAG39_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IAG39_00010	COG0592	DNA-directed DNA polymerase activity
IAG39_00025	COG0583	DNA-binding transcription factor activity
IAG39_00040	COG1741	Belongs to the pirin family
IAG39_00050	COG1574	metal-dependent hydrolase with the TIM-barrel fold
IAG39_00070	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IAG39_00075	COG0583	DNA-binding transcription factor activity
IAG39_00080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAG39_00085	COG0765	amino acid transport
IAG39_00090	COG0765	amino acid transport
IAG39_00095	COG1126	abc transporter atp-binding protein
IAG39_00120	COG1304	FMN binding
IAG39_00135	COG0402	S-adenosylhomocysteine deaminase activity
IAG39_00145	COG4603	Belongs to the binding-protein-dependent transport system permease family
IAG39_00150	COG3845	ABC transporter
IAG39_00155	COG1744	ABC transporter substrate-binding protein PnrA-like
IAG39_00160	COG0586	Pfam SNARE associated Golgi protein
IAG39_00165	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IAG39_00180	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IAG39_00195	COG2814	Major facilitator Superfamily
IAG39_00210	COG3781	membrane
IAG39_00215	COG1522	sequence-specific DNA binding
IAG39_00220	COG0028	Belongs to the TPP enzyme family
IAG39_00225	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_00230	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IAG39_00235	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IAG39_00245	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IAG39_00245	COG0551	DNA topoisomerase type I activity
IAG39_00255	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IAG39_00260	COG2922	Belongs to the Smg family
IAG39_00270	COG2358	TRAP transporter, solute receptor (TAXI family
IAG39_00305	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IAG39_00310	COG3422	double-strand break repair
IAG39_00330	COG2433	Pfam Transposase IS66
IAG39_00340	COG4581	dead DEAH box helicase
IAG39_00355	COG0110	maltose O-acetyltransferase activity
IAG39_00380	COG3339	Conserved Protein
IAG39_00415	COG2957	Belongs to the agmatine deiminase family
IAG39_00420	COG0583	DNA-binding transcription factor activity
IAG39_00465	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IAG39_00470	COG0183	Belongs to the thiolase family
IAG39_00475	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
IAG39_00480	COG1960	acyl-CoA dehydrogenase activity
IAG39_00485	COG1473	amidohydrolase
IAG39_00495	COG1742	UPF0060 membrane protein
IAG39_00505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IAG39_00510	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_00520	COG0778	Nitroreductase
IAG39_00540	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IAG39_00550	COG0018	arginyl-trna synthetase
IAG39_00565	COG0395	ABC-type sugar transport system, permease component
IAG39_00570	COG1175	transmembrane transport
IAG39_00575	COG1653	transport
IAG39_00580	COG3842	ATPase activity
IAG39_00585	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IAG39_00590	COG1609	Transcriptional regulator
IAG39_00595	COG0154	amidase activity
IAG39_00600	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IAG39_00610	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
IAG39_00620	COG0583	DNA-binding transcription factor activity
IAG39_00640	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IAG39_00645	COG1280	lysine exporter protein (LysE YggA)
IAG39_00650	COG0513	Belongs to the DEAD box helicase family
IAG39_00655	COG5339	Protein conserved in bacteria
IAG39_00665	COG4172	Belongs to the ABC transporter superfamily
IAG39_00670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAG39_00675	COG0601	transmembrane transport
IAG39_00680	COG0747	negative chemotaxis
IAG39_00685	COG1160	GTP binding
IAG39_00695	COG3708	Transcriptional regulator
IAG39_00695	COG2207	Transcriptional regulator
IAG39_00705	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IAG39_00715	COG0583	DNA-binding transcription factor activity
IAG39_00725	COG1414	Transcriptional regulator
IAG39_00730	COG0154	amidase activity
IAG39_00745	COG2969	positive regulation of protein catabolic process
IAG39_00750	COG0625	glutathione transferase activity
IAG39_00755	COG2857	Cytochrome c1
IAG39_00760	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IAG39_00765	COG0723	plastoquinol--plastocyanin reductase activity
IAG39_00770	COG1970	mechanosensitive ion channel activity
IAG39_00775	COG0235	Class ii aldolase
IAG39_00785	COG0477	Major facilitator Superfamily
IAG39_00795	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IAG39_00800	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IAG39_00815	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IAG39_00820	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IAG39_00825	COG0537	adenosine 5'-monophosphoramidase activity
IAG39_00830	COG0140	phosphoribosyl-ATP diphosphatase activity
IAG39_00840	COG0107	imidazoleglycerol-phosphate synthase activity
IAG39_00845	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IAG39_00850	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IAG39_00855	COG0131	Imidazoleglycerol-phosphate dehydratase
IAG39_00860	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IAG39_00865	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IAG39_00870	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IAG39_00875	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IAG39_00885	COG0842	Transport permease protein
IAG39_00890	COG1131	(ABC) transporter
IAG39_00900	COG2853	Lipoprotein
IAG39_00905	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IAG39_00910	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IAG39_00915	COG1127	ABC transporter
IAG39_00920	COG2070	2-Nitropropane dioxygenase
IAG39_00930	COG0477	Major facilitator Superfamily
IAG39_00935	COG0583	DNA-binding transcription factor activity
IAG39_00950	COG0070	glutamate synthase
IAG39_00950	COG0067	glutamate synthase
IAG39_00950	COG0069	glutamate synthase activity
IAG39_00975	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IAG39_00995	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IAG39_01025	COG1612	heme a metabolic process
IAG39_01035	COG1999	signal sequence binding
IAG39_01055	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IAG39_01060	COG2814	Major facilitator Superfamily
IAG39_01070	COG0438	transferase activity, transferring glycosyl groups
IAG39_01075	COG1522	sequence-specific DNA binding
IAG39_01090	COG0457	Tetratricopeptide repeat
IAG39_01095	COG0438	transferase activity, transferring glycosyl groups
IAG39_01120	COG4783	chaperone-mediated protein folding
IAG39_01120	COG1560	Kdo2-lipid A biosynthetic process
IAG39_01135	COG3550	peptidyl-serine autophosphorylation
IAG39_01145	COG2814	Major facilitator Superfamily
IAG39_01150	COG0642	Histidine kinase
IAG39_01185	COG1764	response to oxidative stress
IAG39_01200	COG3246	L-lysine catabolic process to acetate
IAG39_01210	COG0861	Integral membrane protein TerC family
IAG39_01220	COG0484	heat shock protein binding
IAG39_01225	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IAG39_01230	COG1960	acyl-CoA dehydrogenase activity
IAG39_01240	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_01260	COG2030	dehydratase
IAG39_01260	COG1012	belongs to the aldehyde dehydrogenase family
IAG39_01270	COG1414	Transcriptional regulator
IAG39_01295	COG0656	L-ascorbic acid biosynthetic process
IAG39_01300	COG0583	DNA-binding transcription factor activity
IAG39_01305	COG2423	ornithine cyclodeaminase activity
IAG39_01315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAG39_01320	COG0747	negative chemotaxis
IAG39_01325	COG0402	S-adenosylhomocysteine deaminase activity
IAG39_01330	COG4172	Belongs to the ABC transporter superfamily
IAG39_01340	COG0583	DNA-binding transcription factor activity
IAG39_01355	COG1522	sequence-specific DNA binding
IAG39_01360	COG2423	ornithine cyclodeaminase activity
IAG39_01370	COG0218	Necessary for normal cell division and for the maintenance of normal septation
IAG39_01375	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IAG39_01385	COG0438	transferase activity, transferring glycosyl groups
IAG39_01390	COG0737	Belongs to the 5'-nucleotidase family
IAG39_01420	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IAG39_01440	COG2814	Major facilitator Superfamily
IAG39_01450	COG0583	DNA-binding transcription factor activity
IAG39_01455	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_01460	COG1473	amidohydrolase
IAG39_01465	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IAG39_01515	COG1802	Transcriptional regulator
IAG39_01525	COG3069	C4-dicarboxylate transmembrane transporter activity
IAG39_01540	COG0543	2 iron, 2 sulfur cluster binding
IAG39_01540	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IAG39_01550	COG0431	NADPH-dependent FMN reductase
IAG39_01560	COG1116	anion transmembrane transporter activity
IAG39_01570	COG3064	Membrane
IAG39_01595	COG1607	acyl-coa hydrolase
IAG39_01610	COG0437	4 iron, 4 sulfur cluster binding
IAG39_01615	COG2864	formate dehydrogenase
IAG39_01625	COG1921	L-seryl-tRNASec selenium transferase activity
IAG39_01630	COG3276	selenocysteine insertion sequence binding
IAG39_01645	COG1305	Transglutaminase-like
IAG39_01650	COG0709	Synthesizes selenophosphate from selenide and ATP
IAG39_01685	COG1012	belongs to the aldehyde dehydrogenase family
IAG39_01690	COG3284	Transcriptional regulator
IAG39_01695	COG0134	indole-3-glycerol-phosphate synthase activity
IAG39_01705	COG0512	Glutamine amidotransferase of anthranilate synthase
IAG39_01715	COG0546	phosphoglycolate phosphatase activity
IAG39_01720	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IAG39_01725	COG2967	ApaG domain
IAG39_01730	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
IAG39_01735	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IAG39_01745	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IAG39_01750	COG0037	tRNA processing
IAG39_01765	COG0596	Alpha beta hydrolase
IAG39_01770	COG0583	DNA-binding transcription factor activity
IAG39_01775	COG0683	leucine binding
IAG39_01780	COG0559	Belongs to the binding-protein-dependent transport system permease family
IAG39_01800	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IAG39_01825	COG3473	Maleate cis-trans isomerase
IAG39_01835	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IAG39_01840	COG1024	Enoyl-CoA hydratase
IAG39_01855	COG0356	it plays a direct role in the translocation of protons across the membrane
IAG39_01870	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IAG39_01875	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IAG39_01880	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IAG39_01885	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IAG39_01890	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IAG39_01900	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IAG39_01905	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IAG39_01910	COG0210	DNA helicase
IAG39_01915	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IAG39_01920	COG2171	N-acyltransferase activity
IAG39_01930	COG2195	Cleaves the N-terminal amino acid of tripeptides
IAG39_01940	COG4608	Belongs to the ABC transporter superfamily
IAG39_01945	COG0444	Belongs to the ABC transporter superfamily
IAG39_01950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAG39_01955	COG0601	transmembrane transport
IAG39_01960	COG4166	transmembrane transport
IAG39_01965	COG2988	succinylglutamate desuccinylase activity
IAG39_01970	COG0583	DNA-binding transcription factor activity
IAG39_01975	COG0747	negative chemotaxis
IAG39_01985	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IAG39_01990	COG1024	Enoyl-CoA hydratase
IAG39_01995	COG1024	Enoyl-CoA hydratase
IAG39_02005	COG1309	transcriptional regulator
IAG39_02015	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IAG39_02020	COG1250	3-hydroxyacyl-CoA dehydrogenase
IAG39_02035	COG0523	cobalamin synthesis protein
IAG39_02045	COG0583	DNA-binding transcription factor activity
IAG39_02080	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
IAG39_02090	COG2188	Transcriptional regulator
IAG39_02095	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IAG39_02115	COG1172	Belongs to the binding-protein-dependent transport system permease family
IAG39_02120	COG0667	Aldo Keto reductase
IAG39_02130	COG0633	Ferredoxin
IAG39_02135	COG0784	Response regulator, receiver
IAG39_02135	COG2205	protein histidine kinase activity
IAG39_02185	COG1764	response to oxidative stress
IAG39_02190	COG0583	DNA-binding transcription factor activity
IAG39_02200	COG1595	DNA-templated transcription, initiation
IAG39_02230	COG0179	Fumarylacetoacetate (FAA) hydrolase
IAG39_02260	COG1802	Transcriptional regulator
IAG39_02270	COG0583	DNA-binding transcription factor activity
IAG39_02290	COG2918	glutathione biosynthetic process
IAG39_02305	COG2197	response regulator
IAG39_02315	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
IAG39_02320	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IAG39_02330	COG2721	sulfolactate sulfo-lyase activity
IAG39_02335	COG2721	sulfolactate sulfo-lyase activity
IAG39_02340	COG2188	Transcriptional regulator
IAG39_02350	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IAG39_02350	COG2813	Specifically methylates the guanine in position
IAG39_02355	COG2223	nitrite transmembrane transporter activity
IAG39_02365	COG2860	membrane
IAG39_02370	COG1802	Transcriptional regulator
IAG39_02380	COG1984	allophanate hydrolase subunit 2
IAG39_02385	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
IAG39_02395	COG0583	DNA-binding transcription factor activity
IAG39_02400	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IAG39_02410	COG0642	Histidine kinase
IAG39_02425	COG0745	RESPONSE REGULATOR receiver
IAG39_02430	COG2226	methyltransferase
IAG39_02445	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IAG39_02455	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
IAG39_02465	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IAG39_02470	COG0351	phosphomethylpyrimidine kinase
IAG39_02475	COG2022	thiamine diphosphate biosynthetic process
IAG39_02480	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IAG39_02485	COG4771	TonB-dependent receptor
IAG39_02500	COG0318	PFAM AMP-dependent synthetase and ligase
IAG39_02530	COG0583	DNA-binding transcription factor activity
IAG39_02545	COG0625	glutathione transferase activity
IAG39_02550	COG1053	succinate dehydrogenase
IAG39_02560	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_02590	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_02595	COG1802	Transcriptional regulator
IAG39_02600	COG0288	reversible hydration of carbon dioxide
IAG39_02620	COG2226	methyltransferase
IAG39_02630	COG1194	a g-specific adenine glycosylase
IAG39_02655	COG4638	Rieske (2fe-2S)
IAG39_02660	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IAG39_02665	COG1335	isochorismatase
IAG39_02670	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_02680	COG0741	lytic transglycosylase activity
IAG39_02685	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IAG39_02690	COG0352	thiamine-phosphate diphosphorylase activity
IAG39_02695	COG0352	thiamine-phosphate diphosphorylase activity
IAG39_02695	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IAG39_02695	COG0351	phosphomethylpyrimidine kinase
IAG39_02705	COG1678	Uncharacterized ACR, COG1678
IAG39_02710	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IAG39_02715	COG0540	Belongs to the ATCase OTCase family
IAG39_02730	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IAG39_02740	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IAG39_02745	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IAG39_02760	COG1175	transmembrane transport
IAG39_02785	COG0477	Major facilitator Superfamily
IAG39_02795	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IAG39_02800	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IAG39_02820	COG0237	dephospho-CoA kinase activity
IAG39_02825	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
IAG39_02855	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_02860	COG0583	DNA-binding transcription factor activity
IAG39_02865	COG0154	amidase activity
IAG39_02870	COG0683	leucine binding
IAG39_02875	COG0583	DNA-binding transcription factor activity
IAG39_02925	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IAG39_02985	COG2199	diguanylate cyclase activity
IAG39_02985	COG2202	Pas domain
IAG39_02985	COG2200	EAL domain
IAG39_03000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IAG39_03005	COG0583	DNA-binding transcription factor activity
IAG39_03010	COG0628	permease
IAG39_03025	COG3121	Chaperone
IAG39_03030	COG3188	usher protein
IAG39_03040	COG0477	Major facilitator Superfamily
IAG39_03050	COG0697	spore germination
IAG39_03055	COG1695	Transcriptional regulator
IAG39_03120	COG0583	DNA-binding transcription factor activity
IAG39_03125	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_03135	COG3246	L-lysine catabolic process to acetate
IAG39_03140	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IAG39_03145	COG1172	Belongs to the binding-protein-dependent transport system permease family
IAG39_03150	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IAG39_03160	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IAG39_03185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAG39_03200	COG0583	DNA-binding transcription factor activity
IAG39_03210	COG4221	oxidoreductase activity
IAG39_03250	COG2233	PERMEase
IAG39_03260	COG0326	Molecular chaperone. Has ATPase activity
IAG39_03265	COG1396	sequence-specific DNA binding
IAG39_03275	COG0604	alcohol dehydrogenase
IAG39_03285	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_03310	COG2814	Major facilitator Superfamily
IAG39_03320	COG2271	Major facilitator Superfamily
IAG39_03325	COG4948	Mandelate Racemase Muconate Lactonizing
IAG39_03330	COG0800	Aldolase
IAG39_03335	COG3734	2-keto-3-deoxy-galactonokinase
IAG39_03340	COG1414	Transcriptional regulator
IAG39_03345	COG0625	glutathione transferase activity
IAG39_03360	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IAG39_03365	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IAG39_03370	COG1652	LysM domain
IAG39_03390	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IAG39_03415	COG2207	Transcriptional regulator
IAG39_03420	COG0596	Alpha beta hydrolase
IAG39_03425	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_03435	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IAG39_03440	COG1960	acyl-CoA dehydrogenase activity
IAG39_03445	COG1960	acyl-CoA dehydrogenase activity
IAG39_03455	COG1473	amidohydrolase
IAG39_03460	COG1448	Aminotransferase
IAG39_03465	COG0179	Fumarylacetoacetate (FAA) hydrolase
IAG39_03480	COG0318	PFAM AMP-dependent synthetase and ligase
IAG39_03485	COG0318	PFAM AMP-dependent synthetase and ligase
IAG39_03490	COG1309	transcriptional regulator
IAG39_03520	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_03525	COG1960	acyl-CoA dehydrogenase activity
IAG39_03530	COG1024	Enoyl-CoA hydratase
IAG39_03555	COG3279	Response regulator of the LytR AlgR family
IAG39_03560	COG3275	phosphorelay sensor kinase activity
IAG39_03575	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IAG39_03585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IAG39_03590	COG0006	proline dipeptidase activity
IAG39_03615	COG0688	phosphatidylethanolamine metabolic process
IAG39_03650	COG0505	Belongs to the CarA family
IAG39_03660	COG0477	Major facilitator Superfamily
IAG39_03670	COG1802	Transcriptional regulator
IAG39_03675	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_03685	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IAG39_03700	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IAG39_03715	COG3135	benzoate transporter
IAG39_03725	COG2072	flavoprotein involved in K transport
IAG39_03730	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_03735	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IAG39_03750	COG0583	DNA-binding transcription factor activity
IAG39_03760	COG2249	NAD(P)H dehydrogenase (quinone) activity
IAG39_03765	COG2130	NADP-dependent
IAG39_03770	COG0165	Argininosuccinate lyase
IAG39_03780	COG0785	Cytochrome C biogenesis protein
IAG39_03785	COG4235	cytochrome complex assembly
IAG39_03790	COG3088	subunit of a heme lyase
IAG39_03795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IAG39_03825	COG4133	protoheme IX ABC transporter activity
IAG39_03855	COG0438	transferase activity, transferring glycosyl groups
IAG39_03900	COG3284	Transcriptional regulator
IAG39_03905	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_03910	COG0596	Alpha beta hydrolase
IAG39_03920	COG0583	DNA-binding transcription factor activity
IAG39_04155	COG0625	glutathione transferase activity
IAG39_04165	COG3258	Cytochrome c
IAG39_04170	COG0583	DNA-binding transcription factor activity
IAG39_04175	COG1053	succinate dehydrogenase
IAG39_04175	COG3976	FMN-binding domain protein
IAG39_04205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IAG39_04215	COG1294	oxidase, subunit
IAG39_04220	COG1271	oxidase subunit
IAG39_04230	COG0697	spore germination
IAG39_04235	COG0778	Nitroreductase
IAG39_04255	COG0842	Transport permease protein
IAG39_04260	COG1129	ABC transporter
IAG39_04260	COG0842	Transport permease protein
IAG39_04265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IAG39_04280	COG2200	EAL domain
IAG39_04285	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IAG39_04290	COG0745	RESPONSE REGULATOR receiver
IAG39_04300	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IAG39_04315	COG1054	Belongs to the UPF0176 family
IAG39_04320	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IAG39_04320	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IAG39_04330	COG0489	protein tyrosine kinase activity
IAG39_04345	COG0717	Belongs to the dCTP deaminase family
IAG39_04355	COG2203	Gaf domain
IAG39_04355	COG3706	GGDEF domain
IAG39_04355	COG4251	negative regulation of phosphorylation
IAG39_04355	COG5001	Diguanylate cyclase
IAG39_04360	COG0456	acetyltransferase
IAG39_04375	COG2081	HI0933 family
IAG39_04390	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IAG39_04395	COG0509	glycine decarboxylation via glycine cleavage system
IAG39_04400	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IAG39_04400	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IAG39_04415	COG0154	amidase activity
IAG39_04420	COG4172	Belongs to the ABC transporter superfamily
IAG39_04425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAG39_04430	COG0601	transmembrane transport
IAG39_04450	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IAG39_04455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IAG39_04480	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
IAG39_04485	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IAG39_04490	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IAG39_04515	COG0438	transferase activity, transferring glycosyl groups
IAG39_04520	COG0438	transferase activity, transferring glycosyl groups
IAG39_04530	COG0166	Belongs to the GPI family
IAG39_04545	COG0277	FAD linked oxidase domain protein
IAG39_04550	COG0745	RESPONSE REGULATOR receiver
IAG39_04555	COG2205	protein histidine kinase activity
IAG39_04565	COG2186	Transcriptional regulator
IAG39_04570	COG1368	sulfuric ester hydrolase activity
IAG39_04575	COG0204	Acyl-transferase
IAG39_04610	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IAG39_04620	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IAG39_04625	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IAG39_04645	COG0193	aminoacyl-tRNA hydrolase activity
IAG39_04655	COG0012	GTP binding
IAG39_04675	COG2814	Major facilitator Superfamily
IAG39_04690	COG3135	benzoate transporter
IAG39_04695	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IAG39_04700	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IAG39_04705	COG0742	ribosomal rna small subunit methyltransferase
IAG39_04725	COG3639	organic phosphonate transmembrane transporter activity
IAG39_04730	COG3639	organic phosphonate transmembrane transporter activity
IAG39_04735	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IAG39_04760	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
IAG39_04765	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IAG39_04775	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IAG39_04780	COG1546	Belongs to the CinA family
IAG39_04780	COG1058	Belongs to the CinA family
IAG39_04785	COG0284	orotidine-5'-phosphate decarboxylase activity
IAG39_04790	COG1252	NADH dehydrogenase
IAG39_04795	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IAG39_04805	COG1063	alcohol dehydrogenase
IAG39_04810	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IAG39_04820	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IAG39_04825	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_04830	COG0179	Fumarylacetoacetate (FAA) hydrolase
IAG39_04835	COG2721	sulfolactate sulfo-lyase activity
IAG39_04840	COG4948	Mandelate Racemase Muconate Lactonizing
IAG39_04845	COG0246	Mannitol dehydrogenase
IAG39_04850	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
IAG39_04860	COG1917	Cupin 2, conserved barrel domain protein
IAG39_04880	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IAG39_04890	COG1846	Transcriptional regulator
IAG39_04900	COG0459	protein refolding
IAG39_04905	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IAG39_04925	COG2267	carboxylic ester hydrolase activity
IAG39_04930	COG0477	Major facilitator Superfamily
IAG39_04960	COG0697	spore germination
IAG39_04995	COG0010	Belongs to the arginase family
IAG39_05005	COG4774	siderophore transport
IAG39_05025	COG2382	esterase
IAG39_05030	COG1733	regulation of RNA biosynthetic process
IAG39_05040	COG0668	transmembrane transport
IAG39_05065	COG2249	NAD(P)H dehydrogenase (quinone) activity
IAG39_05070	COG1802	Transcriptional regulator
IAG39_05080	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_05095	COG1960	acyl-CoA dehydrogenase activity
IAG39_05115	COG1454	alcohol dehydrogenase
IAG39_05120	COG1012	belongs to the aldehyde dehydrogenase family
IAG39_05135	COG1012	belongs to the aldehyde dehydrogenase family
IAG39_05135	COG2030	dehydratase
IAG39_05155	COG0583	DNA-binding transcription factor activity
IAG39_05165	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
IAG39_05165	COG0028	Belongs to the TPP enzyme family
IAG39_05170	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
IAG39_05190	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAG39_05195	COG0625	glutathione transferase activity
IAG39_05205	COG0154	amidase activity
IAG39_05210	COG4608	Belongs to the ABC transporter superfamily
IAG39_05215	COG0444	Belongs to the ABC transporter superfamily
IAG39_05220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAG39_05225	COG0601	transmembrane transport
IAG39_05230	COG0747	negative chemotaxis
IAG39_05245	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
IAG39_05250	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
IAG39_05255	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
IAG39_05290	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IAG39_05355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IAG39_05360	COG1126	abc transporter atp-binding protein
IAG39_05365	COG0765	amino acid transport
IAG39_05370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAG39_05405	COG1280	lysine exporter protein (LysE YggA)
IAG39_05415	COG1960	acyl-CoA dehydrogenase activity
IAG39_05420	COG1960	acyl-CoA dehydrogenase activity
IAG39_05425	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IAG39_05435	COG2030	dehydratase
IAG39_05440	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_05455	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_05465	COG1024	Enoyl-CoA hydratase
IAG39_05470	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IAG39_05495	COG2188	Transcriptional regulator
IAG39_05515	COG2837	iron assimilation
IAG39_05525	COG0667	Aldo Keto reductase
IAG39_05530	COG3795	YCII-related domain
IAG39_05550	COG0519	Catalyzes the synthesis of GMP from XMP
IAG39_05580	COG0625	glutathione transferase activity
IAG39_05595	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IAG39_05605	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IAG39_05610	COG1845	cytochrome c oxidase, subunit III
IAG39_05615	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IAG39_05620	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IAG39_05625	COG0477	Major facilitator Superfamily
IAG39_05655	COG0583	DNA-binding transcription factor activity
IAG39_05660	COG0861	Integral membrane protein TerC family
IAG39_05665	COG4106	trans-aconitate 2-methyltransferase activity
IAG39_05690	COG2207	Transcriptional regulator
IAG39_05695	COG2807	transmembrane transport
IAG39_05715	COG0330	HflC and HflK could
IAG39_05750	COG3712	iron ion homeostasis
IAG39_05770	COG1309	transcriptional regulator
IAG39_05790	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IAG39_05795	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_05800	COG1285	pathogenesis
IAG39_05805	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_05810	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
IAG39_05820	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IAG39_05830	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IAG39_05840	COG0456	acetyltransferase
IAG39_05885	COG0697	spore germination
IAG39_05910	COG0280	phosphate acetyltransferase
IAG39_05910	COG0281	malic enzyme
IAG39_05930	COG4772	TonB-dependent receptor
IAG39_05945	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IAG39_05950	COG1845	cytochrome c oxidase, subunit III
IAG39_05955	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IAG39_05965	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
IAG39_05985	COG1999	signal sequence binding
IAG39_06000	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IAG39_06010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAG39_06015	COG1120	ATPase activity
IAG39_06030	COG4771	TonB-dependent receptor
IAG39_06040	COG1126	abc transporter atp-binding protein
IAG39_06045	COG0765	amino acid transport
IAG39_06050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAG39_06055	COG3191	aminopeptidase activity
IAG39_06060	COG1272	protein, Hemolysin III
IAG39_06065	COG1522	sequence-specific DNA binding
IAG39_06085	COG2378	regulation of single-species biofilm formation
IAG39_06115	COG1595	DNA-templated transcription, initiation
IAG39_06130	COG3720	iron ion transport
IAG39_06135	COG4558	Periplasmic binding protein
IAG39_06140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAG39_06145	COG1120	ATPase activity
IAG39_06150	COG1666	GTP binding
IAG39_06155	COG0583	DNA-binding transcription factor activity
IAG39_06160	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IAG39_06185	COG0671	phosphoesterase, PA-phosphatase related
IAG39_06225	COG0559	Belongs to the binding-protein-dependent transport system permease family
IAG39_06265	COG0456	acetyltransferase
IAG39_06280	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_06285	COG0251	oxidation-reduction process
IAG39_06325	COG0683	leucine binding
IAG39_06330	COG2188	Transcriptional regulator
IAG39_06340	COG0318	PFAM AMP-dependent synthetase and ligase
IAG39_06355	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_06365	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IAG39_06400	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IAG39_06405	COG0583	DNA-binding transcription factor activity
IAG39_06435	COG2223	nitrite transmembrane transporter activity
IAG39_06445	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IAG39_06450	COG3383	formate dehydrogenase (NAD+) activity
IAG39_06470	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IAG39_06475	COG0746	molybdenum cofactor guanylyltransferase activity
IAG39_06480	COG0303	'Molybdopterin
IAG39_06485	COG0521	Mo-molybdopterin cofactor biosynthetic process
IAG39_06500	COG0315	cyclic pyranopterin monophosphate synthase activity
IAG39_06510	COG0412	Dienelactone hydrolase
IAG39_06520	COG0678	peroxiredoxin activity
IAG39_06530	COG0697	spore germination
IAG39_06540	COG3920	Histidine kinase
IAG39_06580	COG0667	Aldo Keto reductase
IAG39_06585	COG0815	Transfers the fatty acyl group on membrane lipoproteins
IAG39_06590	COG4535	Mg2 and Co2 transporter CorC
IAG39_06595	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IAG39_06600	COG1702	phosphate starvation-inducible protein PhoH
IAG39_06605	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IAG39_06615	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IAG39_06625	COG0740	serine-type endopeptidase activity
IAG39_06635	COG0640	Transcriptional regulator
IAG39_06645	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IAG39_06650	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IAG39_06655	COG1862	Preprotein translocase
IAG39_06660	COG0343	queuine tRNA-ribosyltransferase activity
IAG39_06665	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IAG39_06680	COG2027	D-alanyl-D-alanine carboxypeptidase
IAG39_06685	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IAG39_06690	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IAG39_06690	COG1648	precorrin-2 dehydrogenase activity
IAG39_06700	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IAG39_06705	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IAG39_06710	COG1116	anion transmembrane transporter activity
IAG39_06715	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IAG39_06720	COG0243	molybdopterin cofactor binding
IAG39_06730	COG4575	ribosome binding
IAG39_06750	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IAG39_06755	COG0741	lytic transglycosylase activity
IAG39_06760	COG0436	Aminotransferase
IAG39_06770	COG0280	phosphate acetyltransferase
IAG39_06770	COG0281	malic enzyme
IAG39_06780	COG2732	(Barnase) inhibitor
IAG39_06785	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IAG39_06790	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IAG39_06795	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IAG39_06800	COG0126	phosphoglycerate kinase activity
IAG39_06810	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IAG39_06815	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IAG39_06835	COG0625	glutathione transferase activity
IAG39_06855	COG0789	Transcriptional regulator
IAG39_06880	COG0306	phosphate transporter
IAG39_06890	COG0521	Mo-molybdopterin cofactor biosynthetic process
IAG39_06900	COG0739	heme binding
IAG39_06910	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IAG39_06930	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IAG39_06935	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
IAG39_06940	COG3639	organic phosphonate transmembrane transporter activity
IAG39_06955	COG0405	Gamma-glutamyltransferase
IAG39_06960	COG0583	DNA-binding transcription factor activity
IAG39_06965	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
IAG39_06970	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
IAG39_06975	COG3454	Phosphonate metabolism
IAG39_06980	COG2188	Transcriptional regulator
IAG39_06985	COG3624	Phosphonate C-P lyase system protein PhnG
IAG39_06990	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
IAG39_06995	COG3626	phosphonate metabolism
IAG39_07000	COG3627	carbon phosphorus lyase activity
IAG39_07005	COG4107	phosphonate C-P lyase system protein PhnK
IAG39_07010	COG4778	phosphonate C-P lyase system protein PhnL
IAG39_07015	COG3454	Phosphonate metabolism
IAG39_07035	COG1301	dicarboxylic acid transport
IAG39_07055	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
IAG39_07065	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
IAG39_07070	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IAG39_07075	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IAG39_07080	COG0009	L-threonylcarbamoyladenylate synthase
IAG39_07085	COG1414	Transcriptional regulator
IAG39_07090	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IAG39_07105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAG39_07110	COG1414	Transcriptional regulator
IAG39_07115	COG0010	Belongs to the arginase family
IAG39_07120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAG39_07125	COG0765	amino acid transport
IAG39_07130	COG1126	abc transporter atp-binding protein
IAG39_07135	COG0028	Belongs to the TPP enzyme family
IAG39_07180	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IAG39_07200	COG2030	dehydratase
IAG39_07230	COG0028	Belongs to the TPP enzyme family
IAG39_07235	COG0583	DNA-binding transcription factor activity
IAG39_07240	COG4974	Belongs to the 'phage' integrase family
IAG39_07245	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IAG39_07250	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IAG39_07265	COG1686	Belongs to the peptidase S11 family
IAG39_07290	COG1074	ATP-dependent DNA helicase activity
IAG39_07300	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IAG39_07315	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IAG39_07320	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IAG39_07330	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IAG39_07340	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IAG39_07345	COG0505	Belongs to the CarA family
IAG39_07350	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IAG39_07360	COG0406	alpha-ribazole phosphatase activity
IAG39_07370	COG3842	ATPase activity
IAG39_07390	COG2233	PERMEase
IAG39_07395	COG0840	transmembrane signaling receptor activity
IAG39_07400	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IAG39_07405	COG1534	Rna-binding protein
IAG39_07410	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
IAG39_07415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IAG39_07425	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IAG39_07460	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IAG39_07485	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IAG39_07490	COG4654	Cytochrome c, class I
IAG39_07510	COG4191	Histidine kinase
IAG39_07535	COG0431	NADPH-dependent FMN reductase
IAG39_07565	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IAG39_07570	COG0573	inorganic phosphate transmembrane transporter activity
IAG39_07575	COG0581	inorganic phosphate transmembrane transporter activity
IAG39_07590	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IAG39_07605	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IAG39_07645	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IAG39_07655	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IAG39_07665	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_07670	COG1024	Enoyl-CoA hydratase
IAG39_07690	COG1902	pentaerythritol trinitrate reductase activity
IAG39_07700	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_07730	COG2084	Dehydrogenase
IAG39_07740	COG0583	DNA-binding transcription factor activity
IAG39_07755	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
IAG39_07770	COG2433	Pfam Transposase IS66
IAG39_07790	COG2003	Belongs to the UPF0758 family
IAG39_07820	COG4221	oxidoreductase activity
IAG39_07855	COG0653	protein targeting
IAG39_07860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IAG39_07865	COG4774	siderophore transport
IAG39_07870	COG3712	iron ion homeostasis
IAG39_07875	COG1595	DNA-templated transcription, initiation
IAG39_07880	COG1418	mRNA catabolic process
IAG39_07890	COG1984	allophanate hydrolase subunit 2
IAG39_07905	COG0511	ligase activity, forming carbon-carbon bonds
IAG39_07910	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
IAG39_07915	COG0583	DNA-binding transcription factor activity
IAG39_07935	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IAG39_07945	COG0318	PFAM AMP-dependent synthetase and ligase
IAG39_07960	COG1802	Transcriptional regulator
IAG39_07975	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IAG39_07985	COG0747	negative chemotaxis
IAG39_07990	COG4608	Belongs to the ABC transporter superfamily
IAG39_08000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAG39_08005	COG0601	transmembrane transport
IAG39_08010	COG0583	DNA-binding transcription factor activity
IAG39_08025	COG1335	isochorismatase
IAG39_08030	COG1335	isochorismatase
IAG39_08035	COG0583	DNA-binding transcription factor activity
IAG39_08045	COG1609	Transcriptional regulator
IAG39_08055	COG0251	oxidation-reduction process
IAG39_08075	COG0765	amino acid transport
IAG39_08085	COG2207	Transcriptional regulator
IAG39_08090	COG0667	Aldo Keto reductase
IAG39_08100	COG0500	methyltransferase
IAG39_08105	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_08110	COG0604	alcohol dehydrogenase
IAG39_08110	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_08110	COG3321	synthase
IAG39_08125	COG0559	Belongs to the binding-protein-dependent transport system permease family
IAG39_08135	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_08140	COG1250	3-hydroxyacyl-CoA dehydrogenase
IAG39_08145	COG3246	L-lysine catabolic process to acetate
IAG39_08150	COG0371	Dehydrogenase
IAG39_08155	COG1802	Transcriptional regulator
IAG39_08160	COG3959	Transketolase, thiamine diphosphate binding domain
IAG39_08165	COG3958	Transketolase
IAG39_08170	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IAG39_08175	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
IAG39_08180	COG3938	Belongs to the proline racemase family
IAG39_08185	COG1177	transmembrane transport
IAG39_08190	COG1176	ABC-type spermidine putrescine transport system, permease component I
IAG39_08195	COG3842	ATPase activity
IAG39_08250	COG3264	Mechanosensitive ion channel
IAG39_08250	COG1511	domain protein
IAG39_08255	COG0583	DNA-binding transcription factor activity
IAG39_08260	COG0427	acetyl-CoA hydrolase
IAG39_08265	COG0583	DNA-binding transcription factor activity
IAG39_08305	COG1250	3-hydroxyacyl-CoA dehydrogenase
IAG39_08315	COG0477	Major facilitator Superfamily
IAG39_08325	COG0154	amidase activity
IAG39_08340	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IAG39_08355	COG0495	leucyl-tRNA aminoacylation
IAG39_08360	COG2814	Major facilitator Superfamily
IAG39_08365	COG1846	Transcriptional regulator
IAG39_08375	COG1686	Belongs to the peptidase S11 family
IAG39_08410	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IAG39_08415	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IAG39_08420	COG2814	Major facilitator Superfamily
IAG39_08425	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IAG39_08435	COG4176	ABC-type proline glycine betaine transport system permease component
IAG39_08440	COG3448	diguanylate cyclase activity
IAG39_08440	COG4175	Glycine betaine
IAG39_08445	COG1942	4-Oxalocrotonate Tautomerase
IAG39_08465	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IAG39_08470	COG0583	DNA-binding transcription factor activity
IAG39_08480	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IAG39_08490	COG0318	PFAM AMP-dependent synthetase and ligase
IAG39_08500	COG2030	dehydratase
IAG39_08515	COG1960	acyl-CoA dehydrogenase activity
IAG39_08520	COG0318	PFAM AMP-dependent synthetase and ligase
IAG39_08525	COG0330	HflC and HflK could
IAG39_08535	COG0583	DNA-binding transcription factor activity
IAG39_08540	COG0243	molybdopterin cofactor binding
IAG39_08545	COG3781	membrane
IAG39_08565	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
IAG39_08580	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IAG39_08610	COG2186	Transcriptional regulator
IAG39_08615	COG0583	DNA-binding transcription factor activity
IAG39_08650	COG0589	response to stress
IAG39_08685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IAG39_08690	COG2197	response regulator
IAG39_08705	COG0617	tRNA 3'-terminal CCA addition
IAG39_08705	COG0517	IMP dehydrogenase activity
IAG39_08705	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
IAG39_08715	COG0589	response to stress
IAG39_08735	COG0071	Belongs to the small heat shock protein (HSP20) family
IAG39_08750	COG1063	alcohol dehydrogenase
IAG39_08805	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IAG39_08820	COG0277	FAD linked oxidase domain protein
IAG39_08845	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_08860	COG1396	sequence-specific DNA binding
IAG39_08880	COG1012	belongs to the aldehyde dehydrogenase family
IAG39_08900	COG0765	amino acid transport
IAG39_08905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IAG39_08960	COG1278	Cold shock
IAG39_08975	COG4191	Histidine kinase
IAG39_08975	COG0784	Response regulator, receiver
IAG39_09070	COG1278	Cold shock
IAG39_09110	COG0740	serine-type endopeptidase activity
IAG39_09155	COG1196	nuclear chromosome segregation
IAG39_09230	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IAG39_09240	COG0247	lactate metabolic process
IAG39_09250	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_09255	COG3608	succinylglutamate desuccinylase aspartoacylase
IAG39_09255	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IAG39_09280	COG0438	transferase activity, transferring glycosyl groups
IAG39_09300	COG0166	Belongs to the GPI family
IAG39_09345	COG0028	Belongs to the TPP enzyme family
IAG39_09365	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_09405	COG0463	Glycosyl transferase, family 2
IAG39_09410	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IAG39_09415	COG3468	outer membrane autotransporter barrel domain protein
IAG39_09430	COG1802	Transcriptional regulator
IAG39_09460	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IAG39_09530	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IAG39_09680	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_09685	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IAG39_09695	COG0583	DNA-binding transcription factor activity
IAG39_09725	COG2808	Putative FMN-binding domain
IAG39_09735	COG0640	Transcriptional regulator
IAG39_09755	COG2321	neutral zinc metallopeptidase
IAG39_09760	COG0009	L-threonylcarbamoyladenylate synthase
IAG39_09765	COG1994	Peptidase M50
IAG39_09770	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IAG39_09775	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
IAG39_09785	COG2850	peptidyl-arginine hydroxylation
IAG39_09790	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IAG39_10050	COG1705	Flagellar rod assembly protein muramidase FlgJ
IAG39_10050	COG3951	Flagellar rod assembly protein muramidase FlgJ
IAG39_10065	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IAG39_10065	COG2755	lipolytic protein G-D-S-L family
IAG39_10095	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_10100	COG0583	DNA-binding transcription factor activity
IAG39_10125	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_10130	COG0583	DNA-binding transcription factor activity
IAG39_10140	COG3360	Dodecin
IAG39_10160	COG1802	Transcriptional regulator
IAG39_10180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IAG39_10185	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IAG39_10205	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IAG39_10215	COG0235	Class ii aldolase
IAG39_10245	COG0668	transmembrane transport
IAG39_10265	COG0483	inositol monophosphate 1-phosphatase activity
IAG39_10280	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
IAG39_10295	COG4263	nitrous-oxide reductase activity
IAG39_10310	COG1253	flavin adenine dinucleotide binding
IAG39_10315	COG1968	undecaprenyl-diphosphatase activity
IAG39_10320	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IAG39_10335	COG0215	cysteine-tRNA ligase activity
IAG39_10345	COG0825	malonyl-CoA metabolic process
IAG39_10355	COG0527	aspartate kinase activity
IAG39_10365	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
IAG39_10415	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IAG39_10425	COG1414	Transcriptional regulator
IAG39_10435	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_10445	COG1024	Enoyl-CoA hydratase
IAG39_10450	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IAG39_10455	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IAG39_10460	COG0318	PFAM AMP-dependent synthetase and ligase
IAG39_10470	COG0179	Fumarylacetoacetate (FAA) hydrolase
IAG39_10475	COG2186	Transcriptional regulator
IAG39_10485	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IAG39_10490	COG3395	kinase activity
IAG39_10500	COG4774	siderophore transport
IAG39_10510	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_10520	COG0318	PFAM AMP-dependent synthetase and ligase
IAG39_10535	COG0183	Belongs to the thiolase family
IAG39_10540	COG1250	3-hydroxyacyl-CoA dehydrogenase
IAG39_10540	COG1024	Enoyl-CoA hydratase
IAG39_10550	COG1250	3-hydroxyacyl-CoA dehydrogenase
IAG39_10550	COG1024	Enoyl-CoA hydratase
IAG39_10555	COG0183	Belongs to the thiolase family
IAG39_10560	COG1960	acyl-CoA dehydrogenase activity
IAG39_10565	COG1309	transcriptional regulator
IAG39_10575	COG2197	response regulator
IAG39_10580	COG2197	response regulator
IAG39_10585	COG0297	glycogen (starch) synthase activity
IAG39_10590	COG0110	maltose O-acetyltransferase activity
IAG39_10595	COG0463	Glycosyl transferase, family 2
IAG39_10600	COG0438	transferase activity, transferring glycosyl groups
IAG39_10620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IAG39_10665	COG0166	Belongs to the GPI family
IAG39_10670	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IAG39_10675	COG1045	serine acetyltransferase
IAG39_10680	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IAG39_10695	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IAG39_10715	COG0598	Magnesium transport protein CorA
IAG39_10730	COG0601	transmembrane transport
IAG39_10735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAG39_10740	COG4172	Belongs to the ABC transporter superfamily
IAG39_10745	COG1846	Transcriptional regulator
IAG39_10790	COG4964	Belongs to the GSP D family
IAG39_10830	COG3604	Transcriptional regulator
IAG39_10845	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IAG39_10860	COG3384	dioxygenase
IAG39_10865	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IAG39_10870	COG0583	DNA-binding transcription factor activity
IAG39_10875	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_10880	COG0318	PFAM AMP-dependent synthetase and ligase
IAG39_10890	COG1802	Transcriptional regulator
IAG39_10960	COG0517	IMP dehydrogenase activity
IAG39_10965	COG0583	DNA-binding transcription factor activity
IAG39_10970	COG0183	Belongs to the thiolase family
IAG39_10980	COG1024	Enoyl-CoA hydratase
IAG39_10995	COG1960	acyl-CoA dehydrogenase activity
IAG39_11010	COG1802	Transcriptional regulator
IAG39_11020	COG1024	Enoyl-CoA hydratase
IAG39_11025	COG0318	PFAM AMP-dependent synthetase and ligase
IAG39_11035	COG0667	Aldo Keto reductase
IAG39_11045	COG4120	Belongs to the binding-protein-dependent transport system permease family
IAG39_11050	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IAG39_11055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IAG39_11065	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IAG39_11090	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
IAG39_11095	COG0725	ABC transporter, periplasmic molybdate-binding protein
IAG39_11100	COG4149	molybdate abc transporter
IAG39_11105	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IAG39_11130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IAG39_11135	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IAG39_11145	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IAG39_11150	COG0736	holo-[acyl-carrier-protein] synthase activity
IAG39_11165	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IAG39_11175	COG1858	cytochrome C peroxidase
IAG39_11180	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IAG39_11180	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IAG39_11185	COG2224	Isocitrate lyase
IAG39_11195	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IAG39_11195	COG0546	phosphoglycolate phosphatase activity
IAG39_11220	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IAG39_11220	COG4106	trans-aconitate 2-methyltransferase activity
IAG39_11230	COG0156	8-amino-7-oxononanoate synthase activity
IAG39_11250	COG3278	Belongs to the heme-copper respiratory oxidase family
IAG39_11270	COG0348	domain, Protein
IAG39_11285	COG2824	Alkylphosphonate utilization operon protein PhnA
IAG39_11305	COG4948	Mandelate Racemase Muconate Lactonizing
IAG39_11315	COG1131	(ABC) transporter
IAG39_11320	COG0842	Transport permease protein
IAG39_11335	COG0789	Transcriptional regulator
IAG39_11360	COG1272	protein, Hemolysin III
IAG39_11385	COG2169	Transcriptional regulator
IAG39_11420	COG0251	oxidation-reduction process
IAG39_11430	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
IAG39_11475	COG1566	PFAM secretion protein HlyD family protein
IAG39_11500	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
IAG39_11515	COG1228	amidohydrolase
IAG39_11535	COG1250	3-hydroxyacyl-CoA dehydrogenase
IAG39_11545	COG2207	Transcriptional regulator
IAG39_11545	COG3708	Transcriptional regulator
IAG39_11550	COG2814	Major facilitator Superfamily
IAG39_11565	COG1464	Belongs to the NlpA lipoprotein family
IAG39_11570	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IAG39_11575	COG2011	ABC-type metal ion transport system permease component
IAG39_11590	COG2326	polyphosphate kinase activity
IAG39_11600	COG0023	Translation Initiation Factor
IAG39_11605	COG2909	trisaccharide binding
IAG39_11615	COG1063	alcohol dehydrogenase
IAG39_11635	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
IAG39_11650	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_11655	COG1473	amidohydrolase
IAG39_11660	COG0477	Major facilitator Superfamily
IAG39_11670	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_11685	COG0583	DNA-binding transcription factor activity
IAG39_11700	COG2951	lytic endotransglycosylase activity
IAG39_11720	COG0519	Catalyzes the synthesis of GMP from XMP
IAG39_11730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAG39_11735	COG0601	transmembrane transport
IAG39_11795	COG0443	Heat shock 70 kDa protein
IAG39_11820	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IAG39_11825	COG1522	sequence-specific DNA binding
IAG39_11870	COG0625	glutathione transferase activity
IAG39_11875	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IAG39_11880	COG1595	DNA-templated transcription, initiation
IAG39_11895	COG3530	Putative quorum-sensing-regulated virulence factor
IAG39_11925	COG0443	Heat shock 70 kDa protein
IAG39_11930	COG0583	DNA-binding transcription factor activity
IAG39_11940	COG0494	nUDIX hydrolase
IAG39_11970	COG0477	Major facilitator Superfamily
IAG39_11980	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IAG39_11990	COG0542	response to heat
IAG39_12010	COG3485	protocatechuate 3,4-dioxygenase
IAG39_12015	COG1012	belongs to the aldehyde dehydrogenase family
IAG39_12055	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IAG39_12060	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IAG39_12065	COG1802	Transcriptional regulator
IAG39_12075	COG5441	Belongs to the UPF0261 family
IAG39_12080	COG5564	TIM-barrel signal transduction protein
IAG39_12095	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
IAG39_12110	COG1477	protein flavinylation
IAG39_12135	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IAG39_12145	COG1562	ergosterol biosynthetic process
IAG39_12150	COG1562	ergosterol biosynthetic process
IAG39_12155	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IAG39_12160	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_12170	COG1942	4-Oxalocrotonate Tautomerase
IAG39_12180	COG1234	tRNA 3'-trailer cleavage
IAG39_12200	COG3971	2-oxopent-4-enoate hydratase activity
IAG39_12215	COG1012	belongs to the aldehyde dehydrogenase family
IAG39_12220	COG3384	dioxygenase
IAG39_12250	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IAG39_12260	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_12270	COG2186	Transcriptional regulator
IAG39_12300	COG0583	DNA-binding transcription factor activity
IAG39_12310	COG1012	belongs to the aldehyde dehydrogenase family
IAG39_12320	COG0583	DNA-binding transcription factor activity
IAG39_12325	COG0268	Binds directly to 16S ribosomal RNA
IAG39_12335	COG0728	peptidoglycan biosynthetic process
IAG39_12345	COG0563	adenylate kinase activity
IAG39_12350	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
IAG39_12355	COG2835	tetraacyldisaccharide 4'-kinase activity
IAG39_12360	COG1663	tetraacyldisaccharide 4'-kinase activity
IAG39_12370	COG0811	peptide transport
IAG39_12375	COG1570	exodeoxyribonuclease VII activity
IAG39_12380	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IAG39_12395	COG0183	Belongs to the thiolase family
IAG39_12405	COG1278	Cold shock
IAG39_12410	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IAG39_12415	COG2373	Large extracellular alpha-helical protein
IAG39_12420	COG4953	penicillin-binding protein 1C
IAG39_12430	COG2995	paraquat-inducible protein a
IAG39_12435	COG3008	intermembrane lipid transfer
IAG39_12445	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IAG39_12445	COG0506	proline dehydrogenase activity
IAG39_12445	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IAG39_12475	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IAG39_12490	COG1802	Transcriptional regulator
IAG39_12495	COG2271	Major facilitator Superfamily
IAG39_12510	COG1914	H( )-stimulated, divalent metal cation uptake system
IAG39_12515	COG1764	response to oxidative stress
IAG39_12525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAG39_12530	COG0765	amino acid transport
IAG39_12535	COG0765	amino acid transport
IAG39_12540	COG1126	abc transporter atp-binding protein
IAG39_12545	COG1902	pentaerythritol trinitrate reductase activity
IAG39_12560	COG0583	DNA-binding transcription factor activity
IAG39_12600	COG0154	amidase activity
IAG39_12645	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IAG39_12650	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IAG39_12655	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IAG39_12660	COG0196	riboflavin kinase activity
IAG39_12665	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IAG39_12670	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IAG39_12670	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IAG39_12685	COG0210	DNA helicase
IAG39_12695	COG1858	cytochrome C peroxidase
IAG39_12700	COG4771	TonB-dependent receptor
IAG39_12715	COG0488	(ABC) transporter
IAG39_12720	COG2890	protein-(glutamine-N5) methyltransferase activity
IAG39_12730	COG2171	N-acyltransferase activity
IAG39_12765	COG1285	pathogenesis
IAG39_12770	COG3038	cytochrome b561
IAG39_12775	COG2877	3-deoxy-8-phosphooctulonate synthase activity
IAG39_12790	COG3008	intermembrane lipid transfer
IAG39_12810	COG1309	transcriptional regulator
IAG39_12835	COG0251	oxidation-reduction process
IAG39_12860	COG1278	Cold shock
IAG39_12870	COG1278	Cold shock
IAG39_12880	COG0501	Belongs to the peptidase M48B family
IAG39_12885	COG0544	peptidyl-prolyl cis-trans isomerase activity
IAG39_12890	COG0740	serine-type endopeptidase activity
IAG39_12895	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IAG39_12900	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IAG39_12905	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IAG39_12910	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_12915	COG0318	PFAM AMP-dependent synthetase and ligase
IAG39_12935	COG0556	nucleotide-excision repair
IAG39_12940	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IAG39_12950	COG1104	cysteine desulfurase activity
IAG39_12955	COG0822	iron-sulfur transferase activity
IAG39_12965	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IAG39_12970	COG0443	Heat shock 70 kDa protein
IAG39_12975	COG0633	Ferredoxin
IAG39_12980	COG2975	iron-sulfur cluster assembly
IAG39_12985	COG1803	Methylglyoxal synthase
IAG39_12990	COG0583	DNA-binding transcription factor activity
IAG39_13000	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IAG39_13040	COG1022	Amp-dependent synthetase and ligase
IAG39_13045	COG0183	Belongs to the thiolase family
IAG39_13050	COG1309	transcriptional regulator
IAG39_13060	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IAG39_13065	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_13075	COG2271	Major facilitator Superfamily
IAG39_13080	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IAG39_13095	COG1136	(ABC) transporter
IAG39_13100	COG0084	hydrolase, TatD family'
IAG39_13110	COG0745	RESPONSE REGULATOR receiver
IAG39_13115	COG4771	TonB-dependent receptor
IAG39_13120	COG4607	ABC-type enterochelin transport system periplasmic component
IAG39_13125	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAG39_13130	COG4605	iron ion homeostasis
IAG39_13135	COG4604	ABC transporter, ATP-binding protein
IAG39_13145	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IAG39_13155	COG0179	Fumarylacetoacetate (FAA) hydrolase
IAG39_13200	COG1116	anion transmembrane transporter activity
IAG39_13205	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IAG39_13210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IAG39_13245	COG0473	3-isopropylmalate dehydrogenase activity
IAG39_13260	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
IAG39_13280	COG1850	ribulose-bisphosphate carboxylase activity
IAG39_13290	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IAG39_13295	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IAG39_13315	COG0765	amino acid transport
IAG39_13320	COG0765	amino acid transport
IAG39_13325	COG1126	abc transporter atp-binding protein
IAG39_13330	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IAG39_13345	COG2146	nitrite reductase [NAD(P)H] activity
IAG39_13345	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IAG39_13350	COG2146	nitrite reductase [NAD(P)H] activity
IAG39_13350	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IAG39_13355	COG0583	DNA-binding transcription factor activity
IAG39_13365	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IAG39_13375	COG0613	PHP domain protein
IAG39_13385	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IAG39_13390	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IAG39_13390	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IAG39_13400	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IAG39_13400	COG0047	phosphoribosylformylglycinamidine synthase activity
IAG39_13405	COG4774	siderophore transport
IAG39_13410	COG3712	iron ion homeostasis
IAG39_13415	COG1595	DNA-templated transcription, initiation
IAG39_13425	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IAG39_13435	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_13450	COG1917	Cupin 2, conserved barrel domain protein
IAG39_13575	COG0346	lactoylglutathione lyase activity
IAG39_13585	COG5001	Diguanylate cyclase
IAG39_13610	COG0543	2 iron, 2 sulfur cluster binding
IAG39_13610	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IAG39_13615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IAG39_13620	COG0346	lactoylglutathione lyase activity
IAG39_13700	COG4977	sequence-specific DNA binding
IAG39_13705	COG1335	isochorismatase
IAG39_13715	COG4692	amylo-alpha-1,6-glucosidase activity
IAG39_13805	COG0747	negative chemotaxis
IAG39_13810	COG4608	Belongs to the ABC transporter superfamily
IAG39_13815	COG0444	Belongs to the ABC transporter superfamily
IAG39_13820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAG39_13825	COG0601	transmembrane transport
IAG39_13830	COG2072	flavoprotein involved in K transport
IAG39_13855	COG2885	chlorophyll binding
IAG39_13855	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IAG39_13905	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IAG39_13905	COG0519	Catalyzes the synthesis of GMP from XMP
IAG39_13910	COG2814	Major facilitator Superfamily
IAG39_13940	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
IAG39_13945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IAG39_13980	COG1942	4-Oxalocrotonate Tautomerase
IAG39_13990	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
IAG39_14000	COG4221	oxidoreductase activity
IAG39_14005	COG0183	Belongs to the thiolase family
IAG39_14025	COG0583	DNA-binding transcription factor activity
IAG39_14075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IAG39_14125	COG0154	amidase activity
IAG39_14155	COG2201	protein-glutamate methylesterase activity
IAG39_14160	COG2203	Gaf domain
IAG39_14160	COG3706	GGDEF domain
IAG39_14160	COG4251	negative regulation of phosphorylation
IAG39_14160	COG5001	Diguanylate cyclase
IAG39_14175	COG0583	DNA-binding transcription factor activity
IAG39_14190	COG2814	Major facilitator Superfamily
IAG39_14210	COG0583	DNA-binding transcription factor activity
IAG39_14215	COG0583	DNA-binding transcription factor activity
IAG39_14230	COG1116	anion transmembrane transporter activity
IAG39_14240	COG0318	PFAM AMP-dependent synthetase and ligase
IAG39_14245	COG1960	acyl-CoA dehydrogenase activity
IAG39_14250	COG1960	acyl-CoA dehydrogenase activity
IAG39_14255	COG0183	Belongs to the thiolase family
IAG39_14260	COG1024	Enoyl-CoA hydratase
IAG39_14260	COG1250	3-hydroxyacyl-CoA dehydrogenase
IAG39_14265	COG0583	DNA-binding transcription factor activity
IAG39_14275	COG2733	membrane
IAG39_14285	COG0625	glutathione transferase activity
IAG39_14310	COG2885	chlorophyll binding
IAG39_14325	COG0583	DNA-binding transcription factor activity
IAG39_14340	COG0642	Histidine kinase
IAG39_14360	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IAG39_14370	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IAG39_14380	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IAG39_14385	COG1846	Transcriptional regulator
IAG39_14395	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_14415	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IAG39_14420	COG0697	spore germination
IAG39_14430	COG4941	Belongs to the sigma-70 factor family
IAG39_14445	COG3795	YCII-related domain
IAG39_14455	COG3795	YCII-related domain
IAG39_14480	COG1360	Flagellar Motor Protein
IAG39_14500	COG2207	Transcriptional regulator
IAG39_14510	COG1683	Conserved Protein
IAG39_14535	COG1309	transcriptional regulator
IAG39_14555	COG4608	Belongs to the ABC transporter superfamily
IAG39_14560	COG0444	Belongs to the ABC transporter superfamily
IAG39_14565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAG39_14570	COG0601	transmembrane transport
IAG39_14580	COG1802	Transcriptional regulator
IAG39_14585	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IAG39_14595	COG0667	Aldo Keto reductase
IAG39_14610	COG1414	Transcriptional regulator
IAG39_14615	COG1802	Transcriptional regulator
IAG39_14625	COG1473	amidohydrolase
IAG39_14635	COG2764	glyoxalase bleomycin resistance protein dioxygenase
IAG39_14675	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IAG39_14680	COG3706	GGDEF domain
IAG39_14710	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IAG39_14715	COG0436	Aminotransferase
IAG39_14720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAG39_14725	COG0765	amino acid transport
IAG39_14730	COG0765	amino acid transport
IAG39_14770	COG2271	Major facilitator Superfamily
IAG39_14775	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IAG39_14790	COG0587	DNA-directed DNA polymerase activity
IAG39_14805	COG0833	amino acid
IAG39_14810	COG0400	carboxylic ester hydrolase activity
IAG39_14820	COG1566	PFAM secretion protein HlyD family protein
IAG39_14840	COG0720	synthase
IAG39_14845	COG0602	queuosine metabolic process
IAG39_14860	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_14865	COG0154	amidase activity
IAG39_14875	COG1902	pentaerythritol trinitrate reductase activity
IAG39_14910	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IAG39_14925	COG0842	Transport permease protein
IAG39_14930	COG1131	(ABC) transporter
IAG39_14940	COG1309	transcriptional regulator
IAG39_14945	COG2130	NADP-dependent
IAG39_14970	COG3842	ATPase activity
IAG39_14975	COG3842	ATPase activity
IAG39_14985	COG0395	ABC-type sugar transport system, permease component
IAG39_15000	COG2203	Gaf domain
IAG39_15000	COG2199	diguanylate cyclase activity
IAG39_15010	COG3387	PFAM Glycoside hydrolase 15-related
IAG39_15015	COG1960	acyl-CoA dehydrogenase activity
IAG39_15045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IAG39_15050	COG0583	DNA-binding transcription factor activity
IAG39_15060	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IAG39_15065	COG1960	acyl-CoA dehydrogenase activity
IAG39_15070	COG0420	3'-5' exonuclease activity
IAG39_15085	COG1960	acyl-CoA dehydrogenase activity
IAG39_15090	COG1309	transcriptional regulator
IAG39_15100	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IAG39_15120	COG2111	Na H antiporter
IAG39_15120	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IAG39_15125	COG1006	Multisubunit Na H antiporter MnhC subunit
IAG39_15130	COG0651	ATP synthesis coupled electron transport
IAG39_15135	COG1863	multisubunit Na H antiporter MnhE subunit
IAG39_15140	COG2212	antiporter activity
IAG39_15165	COG1619	proteins homologs of microcin C7 resistance protein MccF
IAG39_15185	COG0488	(ABC) transporter
IAG39_15190	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_15195	COG0183	Belongs to the thiolase family
IAG39_15205	COG1024	Enoyl-CoA hydratase
IAG39_15215	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_15220	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IAG39_15250	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IAG39_15255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAG39_15260	COG2252	PERMEase
IAG39_15265	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IAG39_15270	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
IAG39_15280	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IAG39_15305	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IAG39_15310	COG0789	Transcriptional regulator
IAG39_15320	COG0678	peroxiredoxin activity
IAG39_15320	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IAG39_15330	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IAG39_15335	COG0584	glycerophosphoryl diester phosphodiesterase
IAG39_15345	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IAG39_15355	COG4181	ATPase activity
IAG39_15365	COG4208	sulfate ABC transporter
IAG39_15370	COG3842	ATPase activity
IAG39_15375	COG0583	DNA-binding transcription factor activity
IAG39_15380	COG0560	Phosphoserine phosphatase
IAG39_15385	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IAG39_15395	COG0583	DNA-binding transcription factor activity
IAG39_15425	COG0583	DNA-binding transcription factor activity
IAG39_15430	COG4336	lyase activity
IAG39_15460	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IAG39_15500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAG39_15505	COG0765	amino acid transport
IAG39_15510	COG1126	abc transporter atp-binding protein
IAG39_15515	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IAG39_15520	COG1758	RNA polymerase activity
IAG39_15525	COG0194	GDP metabolic process
IAG39_15530	COG3258	Cytochrome c
IAG39_15535	COG2863	cytochrome
IAG39_15540	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_15545	COG0791	NLP P60 protein
IAG39_15550	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IAG39_15555	COG0833	amino acid
IAG39_15560	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IAG39_15565	COG1561	YicC-like family, N-terminal region
IAG39_15570	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IAG39_15580	COG1960	acyl-CoA dehydrogenase activity
IAG39_15595	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IAG39_15600	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IAG39_15605	COG0174	glutamine synthetase
IAG39_15615	COG2204	response regulator
IAG39_15620	COG0583	DNA-binding transcription factor activity
IAG39_15625	COG1741	Belongs to the pirin family
IAG39_15630	COG1741	Belongs to the pirin family
IAG39_15635	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_15640	COG3842	ATPase activity
IAG39_15650	COG1840	ABC-type Fe3 transport system, periplasmic component
IAG39_15660	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_15680	COG0583	DNA-binding transcription factor activity
IAG39_15695	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IAG39_15700	COG0583	DNA-binding transcription factor activity
IAG39_15705	COG0783	Belongs to the Dps family
IAG39_15720	COG0745	RESPONSE REGULATOR receiver
IAG39_15725	COG2205	protein histidine kinase activity
IAG39_15740	COG3842	ATPase activity
IAG39_15745	COG0395	ABC-type sugar transport system, permease component
IAG39_15750	COG1175	transmembrane transport
IAG39_15755	COG1653	transport
IAG39_15765	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IAG39_15775	COG0559	Belongs to the binding-protein-dependent transport system permease family
IAG39_15795	COG1794	racemase activity, acting on amino acids and derivatives
IAG39_15800	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
IAG39_15810	COG0583	DNA-binding transcription factor activity
IAG39_15815	COG0625	glutathione transferase activity
IAG39_15820	COG2133	pyrroloquinoline quinone binding
IAG39_15830	COG0697	spore germination
IAG39_15835	COG2363	Small membrane protein
IAG39_15865	COG0010	Belongs to the arginase family
IAG39_15870	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IAG39_15875	COG1464	Belongs to the NlpA lipoprotein family
IAG39_15880	COG2199	diguanylate cyclase activity
IAG39_15895	COG1408	metallophosphoesterase
IAG39_15905	COG0688	phosphatidylethanolamine metabolic process
IAG39_15920	COG0583	DNA-binding transcription factor activity
IAG39_15935	COG0488	(ABC) transporter
IAG39_15965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IAG39_15970	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IAG39_15975	COG2199	diguanylate cyclase activity
IAG39_15975	COG2200	EAL domain
IAG39_15975	COG2203	Gaf domain
IAG39_15980	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IAG39_15995	COG2814	Major facilitator Superfamily
IAG39_16005	COG0784	Response regulator, receiver
IAG39_16005	COG4191	Histidine kinase
IAG39_16010	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
IAG39_16015	COG2204	response regulator
IAG39_16020	COG2204	response regulator
IAG39_16035	COG2155	Conserved Protein
IAG39_16050	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_16085	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IAG39_16100	COG3300	MHYT domain
IAG39_16100	COG5001	Diguanylate cyclase
IAG39_16115	COG1640	4-alpha-glucanotransferase
IAG39_16120	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IAG39_16130	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IAG39_16140	COG0366	Alpha amylase catalytic
IAG39_16145	COG0297	glycogen (starch) synthase activity
IAG39_16150	COG0028	Belongs to the TPP enzyme family
IAG39_16170	COG0392	lysyltransferase activity
IAG39_16175	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IAG39_16180	COG3568	Endonuclease Exonuclease Phosphatase
IAG39_16195	COG1253	flavin adenine dinucleotide binding
IAG39_16210	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IAG39_16215	COG0714	Associated with various cellular activities
IAG39_16250	COG3119	arylsulfatase activity
IAG39_16285	COG2205	protein histidine kinase activity
IAG39_16295	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IAG39_16330	COG3706	GGDEF domain
IAG39_16345	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
IAG39_16350	COG0628	permease
IAG39_16365	COG1619	proteins homologs of microcin C7 resistance protein MccF
IAG39_16385	COG0531	amino acid
IAG39_16405	COG0625	glutathione transferase activity
IAG39_16430	COG1024	Enoyl-CoA hydratase
IAG39_16435	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IAG39_16450	COG2186	Transcriptional regulator
IAG39_16455	COG2271	Major facilitator Superfamily
IAG39_16470	COG0431	NADPH-dependent FMN reductase
IAG39_16480	COG0798	PFAM Bile acid sodium symporter
IAG39_16490	COG0346	lactoylglutathione lyase activity
IAG39_16525	COG0596	Alpha beta hydrolase
IAG39_16530	COG0045	succinate-CoA ligase (ADP-forming) activity
IAG39_16530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IAG39_16530	COG1042	CoA-binding domain protein
IAG39_16560	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IAG39_16610	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_16615	COG0477	Major facilitator Superfamily
IAG39_16625	COG0583	DNA-binding transcription factor activity
IAG39_16630	COG1335	isochorismatase
IAG39_16635	COG0583	DNA-binding transcription factor activity
IAG39_16655	COG2199	diguanylate cyclase activity
IAG39_16655	COG2200	EAL domain
IAG39_16655	COG2202	Pas domain
IAG39_16660	COG0784	Response regulator, receiver
IAG39_16660	COG2205	protein histidine kinase activity
IAG39_16665	COG2197	response regulator
IAG39_16695	COG0747	negative chemotaxis
IAG39_16705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAG39_16710	COG0444	Belongs to the ABC transporter superfamily
IAG39_16715	COG4608	Belongs to the ABC transporter superfamily
IAG39_16725	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IAG39_16735	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IAG39_16735	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IAG39_16745	COG0028	Belongs to the TPP enzyme family
IAG39_16755	COG1012	belongs to the aldehyde dehydrogenase family
IAG39_16765	COG0235	Class ii aldolase
IAG39_16770	COG0028	Belongs to the TPP enzyme family
IAG39_16775	COG0583	DNA-binding transcription factor activity
IAG39_16790	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_16805	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IAG39_16815	COG0586	Pfam SNARE associated Golgi protein
IAG39_16820	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IAG39_16825	COG0390	transport system, permease component
IAG39_16830	COG0517	IMP dehydrogenase activity
IAG39_16830	COG1125	glycine betaine transport
IAG39_16840	COG1126	abc transporter atp-binding protein
IAG39_16845	COG0765	amino acid transport
IAG39_16850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAG39_16865	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IAG39_16870	COG2267	carboxylic ester hydrolase activity
IAG39_16880	COG0346	lactoylglutathione lyase activity
IAG39_16895	COG0028	Belongs to the TPP enzyme family
IAG39_16905	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IAG39_16915	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IAG39_16935	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IAG39_16965	COG4566	intracellular signal transduction
IAG39_16980	COG0346	lactoylglutathione lyase activity
IAG39_16990	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
IAG39_17010	COG1960	acyl-CoA dehydrogenase activity
IAG39_17025	COG0583	DNA-binding transcription factor activity
IAG39_17040	COG1802	Transcriptional regulator
IAG39_17045	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IAG39_17050	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_17060	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IAG39_17100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAG39_17105	COG4597	amino acid ABC transporter
IAG39_17115	COG3154	lipid carrier protein
IAG39_17120	COG0826	peptidase U32
IAG39_17125	COG0826	peptidase U32
IAG39_17130	COG2197	response regulator
IAG39_17135	COG3850	Histidine kinase
IAG39_17140	COG1763	Mo-molybdopterin cofactor biosynthetic process
IAG39_17145	COG0288	reversible hydration of carbon dioxide
IAG39_17155	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IAG39_17160	COG2181	nitrate reductase activity
IAG39_17165	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
IAG39_17170	COG1140	nitrate reductase beta subunit
IAG39_17175	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IAG39_17180	COG2223	nitrite transmembrane transporter activity
IAG39_17220	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IAG39_17225	COG0583	DNA-binding transcription factor activity
IAG39_17235	COG0784	Response regulator, receiver
IAG39_17235	COG2205	protein histidine kinase activity
IAG39_17240	COG2200	EAL domain
IAG39_17240	COG2199	diguanylate cyclase activity
IAG39_17250	COG2197	response regulator
IAG39_17255	COG3468	outer membrane autotransporter barrel domain protein
IAG39_17330	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IAG39_17350	COG1414	Transcriptional regulator
IAG39_17365	COG1309	transcriptional regulator
IAG39_17380	COG1021	2,3-dihydroxybenzoate-AMP ligase
IAG39_17395	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_17400	COG0583	DNA-binding transcription factor activity
IAG39_17440	COG1328	CTP reductase activity
IAG39_17455	COG2070	2-Nitropropane dioxygenase
IAG39_17465	COG3848	Pyruvate phosphate dikinase
IAG39_17465	COG0574	Belongs to the PEP-utilizing enzyme family
IAG39_17470	COG5002	protein histidine kinase activity
IAG39_17475	COG0745	RESPONSE REGULATOR receiver
IAG39_17480	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
IAG39_17485	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IAG39_17500	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IAG39_17520	COG0783	Belongs to the Dps family
IAG39_17530	COG2879	small protein
IAG39_17535	COG1966	Carbon starvation protein
IAG39_17555	COG4521	taurine ABC transporter
IAG39_17560	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IAG39_17565	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IAG39_17575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IAG39_17585	COG0523	cobalamin synthesis protein
IAG39_17590	COG1228	amidohydrolase
IAG39_17605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAG39_17610	COG0601	transmembrane transport
IAG39_17630	COG1414	Transcriptional regulator
IAG39_17635	COG0513	Belongs to the DEAD box helicase family
IAG39_17660	COG2373	Large extracellular alpha-helical protein
IAG39_17660	COG4932	domain protein
IAG39_17660	COG1388	LysM domain
IAG39_17665	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IAG39_17675	COG0840	transmembrane signaling receptor activity
IAG39_17695	COG2814	Major facilitator Superfamily
IAG39_17700	COG0386	Belongs to the glutathione peroxidase family
IAG39_17705	COG1522	sequence-specific DNA binding
IAG39_17715	COG0625	glutathione transferase activity
IAG39_17740	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IAG39_17745	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IAG39_17750	COG0010	Belongs to the arginase family
IAG39_17755	COG1126	abc transporter atp-binding protein
IAG39_17760	COG0765	amino acid transport
IAG39_17765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAG39_17775	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_17785	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IAG39_17795	COG0154	amidase activity
IAG39_17800	COG0410	ABC transporter
IAG39_17805	COG1137	ATPase activity
IAG39_17825	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IAG39_17830	COG1024	Enoyl-CoA hydratase
IAG39_17840	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IAG39_17855	COG0084	hydrolase, TatD family'
IAG39_17860	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IAG39_17865	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IAG39_17870	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IAG39_17875	COG0354	folic acid binding
IAG39_17895	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IAG39_17900	COG1960	acyl-CoA dehydrogenase activity
IAG39_17905	COG2914	Belongs to the UPF0125 (RnfH) family
IAG39_17910	COG2867	negative regulation of translational initiation
IAG39_17915	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IAG39_17935	COG0519	Catalyzes the synthesis of GMP from XMP
IAG39_17935	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IAG39_17940	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IAG39_17940	COG2169	Transcriptional regulator
IAG39_17965	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IAG39_17970	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IAG39_17985	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IAG39_17990	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IAG39_17995	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
IAG39_18000	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IAG39_18005	COG0750	zinc metalloprotease
IAG39_18010	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
IAG39_18015	COG0575	Belongs to the CDS family
IAG39_18020	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IAG39_18025	COG0233	cytoplasmic translational termination
IAG39_18030	COG0528	UMP kinase activity
IAG39_18035	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IAG39_18040	COG0052	Belongs to the universal ribosomal protein uS2 family
IAG39_18050	COG0024	Methionine aminopeptidase
IAG39_18055	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
IAG39_18065	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
IAG39_18070	COG1451	nucleotide metabolic process
IAG39_18090	COG0285	dihydrofolate synthase activity
IAG39_18100	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_18105	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IAG39_18120	COG1334	flagellar protein FlaG
IAG39_18125	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IAG39_18145	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IAG39_18155	COG1677	Flagellar hook-basal body complex protein FliE
IAG39_18160	COG1766	The M ring may be actively involved in energy transduction
IAG39_18165	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IAG39_18170	COG1317	bacterial-type flagellum organization
IAG39_18175	COG1157	protein secretion by the type III secretion system
IAG39_18190	COG1580	Controls the rotational direction of flagella during chemotaxis
IAG39_18215	COG1987	bacterial-type flagellum assembly
IAG39_18225	COG0840	transmembrane signaling receptor activity
IAG39_18240	COG0840	transmembrane signaling receptor activity
IAG39_18245	COG0840	transmembrane signaling receptor activity
IAG39_18255	COG1256	bacterial-type flagellum assembly
IAG39_18280	COG4787	bacterial-type flagellum-dependent cell motility
IAG39_18295	COG1558	bacterial-type flagellum-dependent cell motility
IAG39_18300	COG1815	bacterial-type flagellum-dependent cell motility
IAG39_18310	COG2747	anti-sigma28 factor FlgM
IAG39_18325	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IAG39_18330	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IAG39_18335	COG0840	transmembrane signaling receptor activity
IAG39_18340	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
IAG39_18345	COG0745	RESPONSE REGULATOR receiver
IAG39_18350	COG2201	protein-glutamate methylesterase activity
IAG39_18355	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IAG39_18360	COG0840	transmembrane signaling receptor activity
IAG39_18365	COG0835	chemotaxis
IAG39_18375	COG0745	RESPONSE REGULATOR receiver
IAG39_18380	COG1360	Flagellar Motor Protein
IAG39_18400	COG1191	sigma factor activity
IAG39_18405	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IAG39_18405	COG4797	methyltransferase
IAG39_18425	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IAG39_18430	COG0508	dehydrogenase complex catalyzes the overall conversion of
IAG39_18445	COG4566	intracellular signal transduction
IAG39_18450	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IAG39_18455	COG0339	signal peptide processing
IAG39_18465	COG1999	signal sequence binding
IAG39_18490	COG0583	DNA-binding transcription factor activity
IAG39_18495	COG1187	pseudouridine synthase activity
IAG39_18540	COG3161	chorismate lyase activity
IAG39_18570	COG0066	3-isopropylmalate dehydratase activity
IAG39_18575	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IAG39_18605	COG2188	Transcriptional regulator
IAG39_18625	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IAG39_18640	COG4681	YaeQ
IAG39_18645	COG1280	lysine exporter protein (LysE YggA)
IAG39_18650	COG4172	Belongs to the ABC transporter superfamily
IAG39_18655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAG39_18660	COG0601	transmembrane transport
IAG39_18665	COG0747	negative chemotaxis
IAG39_18675	COG0583	DNA-binding transcription factor activity
IAG39_18710	COG2165	general secretion pathway protein
IAG39_18775	COG0668	transmembrane transport
IAG39_18780	COG0165	Argininosuccinate lyase
IAG39_18785	COG0583	DNA-binding transcription factor activity
IAG39_18790	COG2814	Major facilitator Superfamily
IAG39_18800	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IAG39_18830	COG0477	Major facilitator Superfamily
IAG39_18865	COG0022	dehydrogenase e1 component
IAG39_18900	COG1024	Enoyl-CoA hydratase
IAG39_18905	COG2186	Transcriptional regulator
IAG39_18910	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IAG39_18915	COG0789	Transcriptional regulator
IAG39_18925	COG0430	RNA-3'-phosphate cyclase activity
IAG39_18930	COG3541	Predicted nucleotidyltransferase
IAG39_18935	COG1690	Belongs to the RtcB family
IAG39_18945	COG4650	regulator
IAG39_18950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IAG39_18960	COG2271	Major facilitator Superfamily
IAG39_18975	COG0307	riboflavin synthase, alpha
IAG39_18985	COG2186	Transcriptional regulator
IAG39_18990	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_19020	COG1595	DNA-templated transcription, initiation
IAG39_19040	COG0583	DNA-binding transcription factor activity
IAG39_19055	COG0318	PFAM AMP-dependent synthetase and ligase
IAG39_19065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IAG39_19095	COG2814	Major facilitator Superfamily
IAG39_19120	COG0559	Belongs to the binding-protein-dependent transport system permease family
IAG39_19135	COG0183	Belongs to the thiolase family
IAG39_19140	COG0318	PFAM AMP-dependent synthetase and ligase
IAG39_19145	COG2186	Transcriptional regulator
IAG39_19170	COG0477	Major facilitator Superfamily
IAG39_19180	COG0583	DNA-binding transcription factor activity
IAG39_19185	COG0251	oxidation-reduction process
IAG39_19195	COG1595	DNA-templated transcription, initiation
IAG39_19200	COG3712	iron ion homeostasis
IAG39_19210	COG0583	DNA-binding transcription factor activity
IAG39_19225	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IAG39_19230	COG1595	DNA-templated transcription, initiation
IAG39_19235	COG3712	iron ion homeostasis
IAG39_19240	COG4774	siderophore transport
IAG39_19250	COG0640	Transcriptional regulator
IAG39_19270	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_19280	COG0411	ABC transporter
IAG39_19315	COG1802	Transcriptional regulator
IAG39_19320	COG5265	(ABC) transporter
IAG39_19340	COG4977	sequence-specific DNA binding
IAG39_19360	COG0318	PFAM AMP-dependent synthetase and ligase
IAG39_19365	COG2188	Transcriptional regulator
IAG39_19380	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IAG39_19400	COG0477	Major facilitator Superfamily
IAG39_19405	COG0235	Class ii aldolase
IAG39_19415	COG1051	belongs to the nudix hydrolase family
IAG39_19420	COG0583	DNA-binding transcription factor activity
IAG39_19430	COG2223	nitrite transmembrane transporter activity
IAG39_19440	COG2610	gluconate transmembrane transporter activity
IAG39_19445	COG0583	DNA-binding transcription factor activity
IAG39_19450	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_19455	COG1024	Enoyl-CoA hydratase
IAG39_19460	COG5001	Diguanylate cyclase
IAG39_19465	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_19470	COG0129	dihydroxy-acid dehydratase activity
IAG39_19495	COG2226	methyltransferase
IAG39_19510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IAG39_19515	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IAG39_19540	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IAG39_19560	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IAG39_19565	COG1335	isochorismatase
IAG39_19570	COG2309	aminopeptidase activity
IAG39_19575	COG0596	Alpha beta hydrolase
IAG39_19600	COG0583	DNA-binding transcription factor activity
IAG39_19605	COG1250	3-hydroxyacyl-CoA dehydrogenase
IAG39_19610	COG3246	L-lysine catabolic process to acetate
IAG39_19625	COG0583	DNA-binding transcription factor activity
IAG39_19645	COG3043	anaerobic respiration
IAG39_19650	COG3005	denitrification pathway
IAG39_19655	COG4133	protoheme IX ABC transporter activity
IAG39_19675	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
IAG39_19685	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IAG39_19765	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IAG39_19775	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_19785	COG2084	Dehydrogenase
IAG39_19790	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_19800	COG2186	Transcriptional regulator
IAG39_19805	COG0154	amidase activity
IAG39_19830	COG1129	ABC transporter
IAG39_19835	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
IAG39_19845	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
IAG39_19850	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IAG39_19860	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_19865	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IAG39_19870	COG0583	DNA-binding transcription factor activity
IAG39_19890	COG0697	spore germination
IAG39_19895	COG0697	spore germination
IAG39_19915	COG0183	Belongs to the thiolase family
IAG39_19920	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_19925	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IAG39_19935	COG0583	DNA-binding transcription factor activity
IAG39_19945	COG1280	lysine exporter protein (LysE YggA)
IAG39_19960	COG1280	lysine exporter protein (LysE YggA)
IAG39_19965	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
IAG39_19970	COG3245	cytochrome
IAG39_19980	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IAG39_20010	COG0318	PFAM AMP-dependent synthetase and ligase
IAG39_20015	COG1960	acyl-CoA dehydrogenase activity
IAG39_20020	COG2814	Major facilitator Superfamily
IAG39_20035	COG0625	glutathione transferase activity
IAG39_20040	COG0583	DNA-binding transcription factor activity
IAG39_20045	COG0583	DNA-binding transcription factor activity
IAG39_20060	COG0506	proline dehydrogenase activity
IAG39_20065	COG0697	spore germination
IAG39_20070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IAG39_20100	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IAG39_20105	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IAG39_20155	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IAG39_20165	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_20170	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IAG39_20180	COG1610	YqeY-like protein
IAG39_20225	COG0457	Tetratricopeptide repeat
IAG39_20230	COG0726	polysaccharide deacetylase
IAG39_20230	COG1649	PFAM Uncharacterised BCR, COG1649
IAG39_20235	COG1215	transferase activity, transferring glycosyl groups
IAG39_20245	COG2223	nitrite transmembrane transporter activity
IAG39_20250	COG4977	sequence-specific DNA binding
IAG39_20250	COG1917	Cupin 2, conserved barrel domain protein
IAG39_20260	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IAG39_20275	COG0656	L-ascorbic acid biosynthetic process
IAG39_20280	COG5265	(ABC) transporter
IAG39_20295	COG0583	DNA-binding transcription factor activity
IAG39_20310	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_20350	COG1522	sequence-specific DNA binding
IAG39_20375	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_20385	COG0456	acetyltransferase
IAG39_20390	COG0384	phenazine biosynthesis protein PhzF
IAG39_20405	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IAG39_20410	COG0583	DNA-binding transcription factor activity
IAG39_20415	COG0129	dihydroxy-acid dehydratase activity
IAG39_20420	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_20425	COG1250	3-hydroxyacyl-CoA dehydrogenase
IAG39_20475	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IAG39_20475	COG0072	phenylalanine-tRNA ligase activity
IAG39_20480	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IAG39_20485	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IAG39_20490	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IAG39_20495	COG0606	chelatase, subunit chli
IAG39_20500	COG2960	long-chain fatty acid transporting porin activity
IAG39_20510	COG0347	Belongs to the P(II) protein family
IAG39_20515	COG0004	ammonium transporteR
IAG39_20520	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IAG39_20525	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IAG39_20540	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IAG39_20545	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IAG39_20555	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IAG39_20580	COG0601	transmembrane transport
IAG39_20585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAG39_20590	COG4172	Belongs to the ABC transporter superfamily
IAG39_20610	COG1609	Transcriptional regulator
IAG39_20615	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IAG39_20620	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IAG39_20625	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IAG39_20630	COG0129	dihydroxy-acid dehydratase activity
IAG39_20655	COG0135	phosphoribosylanthranilate isomerase activity
IAG39_20660	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IAG39_20675	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IAG39_20695	COG1538	Outer membrane efflux protein
IAG39_20710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IAG39_20785	COG4783	chaperone-mediated protein folding
IAG39_20790	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IAG39_20805	COG5002	protein histidine kinase activity
IAG39_20825	COG1295	ribonuclease BN
IAG39_20835	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IAG39_20865	COG4964	Belongs to the GSP D family
IAG39_20895	COG2030	dehydratase
IAG39_20900	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_20915	COG0439	Biotin carboxylase
IAG39_20920	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IAG39_20925	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IAG39_20975	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IAG39_20985	COG0828	Belongs to the bacterial ribosomal protein bS21 family
IAG39_20990	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
IAG39_20995	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IAG39_21000	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IAG39_21005	COG0330	HflC and HflK could
IAG39_21010	COG0330	HflC and HflK could
IAG39_21015	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IAG39_21020	COG1923	regulation of RNA biosynthetic process
IAG39_21025	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IAG39_21030	COG1160	GTP binding
IAG39_21035	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IAG39_21040	COG2976	Protein conserved in bacteria
IAG39_21060	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IAG39_21065	COG0105	UTP biosynthetic process
IAG39_21070	COG0525	valine-tRNA ligase activity
IAG39_21075	COG0336	Belongs to the RNA methyltransferase TrmD family
IAG39_21085	COG0228	four-way junction DNA binding
IAG39_21095	COG0425	Belongs to the sulfur carrier protein TusA family
IAG39_21100	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IAG39_21150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IAG39_21160	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
IAG39_21165	COG2076	Multidrug Resistance protein
IAG39_21170	COG3217	Mosc domain protein beta barrel domain protein
IAG39_21170	COG0633	Ferredoxin
IAG39_21175	COG5285	phytanoyl-CoA dioxygenase
IAG39_21180	COG0662	Cupin 2, conserved barrel domain protein
IAG39_21205	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IAG39_21210	COG2358	TRAP transporter, solute receptor (TAXI family
IAG39_21220	COG2311	Membrane
IAG39_21250	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IAG39_21260	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IAG39_21265	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IAG39_21285	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IAG39_21295	COG3391	amine dehydrogenase activity
IAG39_21325	COG1846	Transcriptional regulator
IAG39_21335	COG1566	PFAM secretion protein HlyD family protein
IAG39_21340	COG2814	Major facilitator Superfamily
IAG39_21350	COG0473	3-isopropylmalate dehydrogenase activity
IAG39_21355	COG0433	COG0433 Predicted ATPase
IAG39_21360	COG0217	transcriptional regulatory protein
IAG39_21365	COG0151	Belongs to the GarS family
IAG39_21375	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IAG39_21380	COG0799	negative regulation of ribosome biogenesis
IAG39_21385	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IAG39_21395	COG1301	dicarboxylic acid transport
IAG39_21400	COG4191	Histidine kinase
IAG39_21405	COG2204	response regulator
IAG39_21435	COG1530	ribonuclease E activity
IAG39_21440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IAG39_21445	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IAG39_21450	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IAG39_21450	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IAG39_21470	COG2203	Gaf domain
IAG39_21470	COG3706	GGDEF domain
IAG39_21470	COG4251	negative regulation of phosphorylation
IAG39_21470	COG5001	Diguanylate cyclase
IAG39_21480	COG0475	glutathione-regulated potassium exporter activity
IAG39_21480	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IAG39_21485	COG1132	(ABC) transporter
IAG39_21490	COG0859	PFAM glycosyl transferase family 9
IAG39_21510	COG0726	polysaccharide deacetylase
IAG39_21525	COG0726	polysaccharide deacetylase
IAG39_21530	COG0438	transferase activity, transferring glycosyl groups
IAG39_21545	COG1116	anion transmembrane transporter activity
IAG39_21555	COG1643	Atp-dependent helicase
IAG39_21560	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IAG39_21560	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IAG39_21565	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
IAG39_21575	COG0704	Plays a role in the regulation of phosphate uptake
IAG39_21580	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IAG39_21585	COG1960	acyl-CoA dehydrogenase activity
IAG39_21595	COG1322	Protein conserved in bacteria
IAG39_21615	COG1177	transmembrane transport
IAG39_21620	COG1176	ABC-type spermidine putrescine transport system, permease component I
IAG39_21625	COG3842	ATPase activity
IAG39_21635	COG3642	lipopolysaccharide core region biosynthetic process
IAG39_21645	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
IAG39_21650	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IAG39_21660	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IAG39_21660	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IAG39_21685	COG1136	(ABC) transporter
IAG39_21690	COG0577	efflux transmembrane transporter activity
IAG39_21690	COG1136	(ABC) transporter
IAG39_21695	COG4608	Belongs to the ABC transporter superfamily
IAG39_21700	COG0444	Belongs to the ABC transporter superfamily
IAG39_21715	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAG39_21720	COG0601	transmembrane transport
IAG39_21725	COG0747	negative chemotaxis
IAG39_21745	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IAG39_21750	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IAG39_21775	COG0583	DNA-binding transcription factor activity
IAG39_21780	COG0137	argininosuccinate synthase activity
IAG39_21785	COG3158	transport of potassium into the cell
IAG39_21790	COG0642	Histidine kinase
IAG39_21820	COG0776	regulation of translation
IAG39_21825	COG3128	pkhd-type hydroxylase
IAG39_21830	COG0626	cystathionine gamma-synthase activity
IAG39_21835	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IAG39_21840	COG0557	exoribonuclease II activity
IAG39_21875	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IAG39_21880	COG2391	methyltransferase activity
IAG39_21885	COG0069	glutamate synthase activity
IAG39_21890	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IAG39_21915	COG2226	methyltransferase
IAG39_21940	COG0697	spore germination
IAG39_21960	COG0628	permease
IAG39_21995	COG3909	cytochrome
IAG39_22005	COG0625	glutathione transferase activity
IAG39_22010	COG0730	response to heat
IAG39_22015	COG0482	sulfurtransferase activity
IAG39_22020	COG0583	DNA-binding transcription factor activity
IAG39_22050	COG0247	lactate metabolic process
IAG39_22055	COG0277	FAD linked oxidase domain protein
IAG39_22060	COG0277	FAD linked oxidase domain protein
IAG39_22065	COG0277	FAD linked oxidase domain protein
IAG39_22070	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IAG39_22075	COG0312	modulator of DNA gyrase
IAG39_22090	COG0308	aminopeptidase N
IAG39_22095	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
IAG39_22115	COG0436	Aminotransferase
IAG39_22125	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IAG39_22130	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
IAG39_22160	COG0559	Belongs to the binding-protein-dependent transport system permease family
IAG39_22190	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_22200	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IAG39_22220	COG0181	hydroxymethylbilane synthase activity
IAG39_22225	COG0861	Integral membrane protein TerC family
IAG39_22230	COG0861	Integral membrane protein TerC family
IAG39_22235	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IAG39_22240	COG0045	succinate-CoA ligase (ADP-forming) activity
IAG39_22255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAG39_22260	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IAG39_22275	COG2137	regulation of response to DNA damage stimulus
IAG39_22280	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IAG39_22315	COG0540	Belongs to the ATCase OTCase family
IAG39_22365	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IAG39_22400	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IAG39_22410	COG0305	Participates in initiation and elongation during chromosome replication
IAG39_22420	COG0359	binds to the 23S rRNA
IAG39_22425	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IAG39_22430	COG2965	DNA replication, synthesis of RNA primer
IAG39_22435	COG0360	Binds together with S18 to 16S ribosomal RNA
IAG39_22440	COG3739	integral membrane protein
IAG39_22445	COG1469	GTP cyclohydrolase I activity
IAG39_22455	COG0142	geranyltranstransferase activity
IAG39_22460	COG1722	exodeoxyribonuclease VII activity
IAG39_22470	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_22490	COG1840	ABC-type Fe3 transport system, periplasmic component
IAG39_22495	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IAG39_22505	COG3842	ATPase activity
IAG39_22525	COG0583	DNA-binding transcription factor activity
IAG39_22540	COG0501	Belongs to the peptidase M48B family
IAG39_22545	COG2706	6-phosphogluconolactonase activity
IAG39_22550	COG1760	l-serine dehydratase
IAG39_22555	COG1283	sodium-dependent phosphate transmembrane transporter activity
IAG39_22560	COG0412	Dienelactone hydrolase
IAG39_22565	COG0428	transporter
IAG39_22580	COG1473	amidohydrolase
IAG39_22585	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_22600	COG2271	Major facilitator Superfamily
IAG39_22615	COG0583	DNA-binding transcription factor activity
IAG39_22625	COG1217	gtp-binding protein TYPA
IAG39_22630	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IAG39_22635	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IAG39_22640	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IAG39_22645	COG2251	uridine kinase activity
IAG39_22645	COG0195	Participates in both transcription termination and antitermination
IAG39_22650	COG0779	Required for maturation of 30S ribosomal subunits
IAG39_22655	COG1187	pseudouridine synthase activity
IAG39_22660	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IAG39_22670	COG0583	DNA-binding transcription factor activity
IAG39_22675	COG0523	cobalamin synthesis protein
IAG39_22695	COG0642	Histidine kinase
IAG39_22700	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IAG39_22705	COG0625	glutathione transferase activity
IAG39_22710	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IAG39_22720	COG2003	Belongs to the UPF0758 family
IAG39_22725	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
IAG39_22730	COG3483	tryptophan 2,3-dioxygenase activity
IAG39_22755	COG2050	protein possibly involved in aromatic compounds catabolism
IAG39_22760	COG1024	Enoyl-CoA hydratase
IAG39_22765	COG1012	belongs to the aldehyde dehydrogenase family
IAG39_22770	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IAG39_22775	COG2151	metal-sulfur cluster biosynthetic enzyme
IAG39_22780	COG3396	Phenylacetate-CoA oxygenase
IAG39_22785	COG3460	Phenylacetate-CoA oxygenase
IAG39_22790	COG3396	Phenylacetate-CoA oxygenase
IAG39_22795	COG3327	negative regulation of DNA-templated transcription, initiation
IAG39_22800	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IAG39_22825	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IAG39_22830	COG0501	Belongs to the peptidase M48B family
IAG39_22835	COG1162	GTPase activity
IAG39_22845	COG0335	large ribosomal subunit rRNA binding
IAG39_22875	COG0175	sulfate reduction
IAG39_22880	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IAG39_22885	COG4208	sulfate ABC transporter
IAG39_22890	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IAG39_22895	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IAG39_22900	COG0450	alkyl hydroperoxide reductase
IAG39_22905	COG1960	acyl-CoA dehydrogenase activity
IAG39_22910	COG2985	domain, Protein
IAG39_22935	COG0123	including yeast histone deacetylase and acetoin utilization protein
IAG39_22940	COG2951	lytic endotransglycosylase activity
IAG39_22970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IAG39_22975	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
IAG39_22980	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
IAG39_23000	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IAG39_23005	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IAG39_23015	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IAG39_23020	COG0077	Prephenate dehydratase
IAG39_23020	COG1605	Chorismate mutase
IAG39_23025	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IAG39_23040	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IAG39_23065	COG1073	alpha beta
IAG39_23080	COG1960	acyl-CoA dehydrogenase activity
IAG39_23090	COG2030	dehydratase
IAG39_23095	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_23105	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_23110	COG2030	dehydratase
IAG39_23110	COG1012	belongs to the aldehyde dehydrogenase family
IAG39_23115	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IAG39_23115	COG1042	CoA-binding domain protein
IAG39_23115	COG0045	succinate-CoA ligase (ADP-forming) activity
IAG39_23120	COG1960	acyl-CoA dehydrogenase activity
IAG39_23130	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IAG39_23135	COG1024	Enoyl-CoA hydratase
IAG39_23140	COG0583	DNA-binding transcription factor activity
IAG39_23155	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_23160	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IAG39_23170	COG1215	transferase activity, transferring glycosyl groups
IAG39_23195	COG2951	lytic endotransglycosylase activity
IAG39_23200	COG2833	Protein of unknown function (DUF455)
IAG39_23215	COG1132	(ABC) transporter
IAG39_23220	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IAG39_23220	COG0189	ligase activity
IAG39_23230	COG3237	CsbD-like
IAG39_23240	COG2823	Periplasmic or secreted lipoprotein
IAG39_23255	COG0672	)-iron permease
IAG39_23275	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
IAG39_23280	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_23285	COG3243	poly(R)-hydroxyalkanoic acid synthase
IAG39_23290	COG1496	oxidoreductase activity
IAG39_23295	COG0564	pseudouridine synthase activity
IAG39_23315	COG1199	ATP-dependent helicase activity
IAG39_23320	COG2183	response to ionizing radiation
IAG39_23355	COG4774	siderophore transport
IAG39_23360	COG3712	iron ion homeostasis
IAG39_23365	COG1595	DNA-templated transcription, initiation
IAG39_23370	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IAG39_23375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IAG39_23380	COG0508	dehydrogenase complex catalyzes the overall conversion of
IAG39_23385	COG0567	Dehydrogenase, E1 component
IAG39_23390	COG1522	sequence-specific DNA binding
IAG39_23395	COG2515	1-aminocyclopropane-1-carboxylate deaminase
IAG39_23410	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IAG39_23415	COG1297	OPT oligopeptide transporter protein
IAG39_23425	COG0281	malic enzyme
IAG39_23425	COG0280	phosphate acetyltransferase
IAG39_23440	COG0372	Belongs to the citrate synthase family
IAG39_23445	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IAG39_23450	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IAG39_23455	COG1053	succinate dehydrogenase
IAG39_23460	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IAG39_23465	COG2009	succinate dehydrogenase
IAG39_23470	COG2188	Transcriptional regulator
IAG39_23475	COG0039	L-malate dehydrogenase activity
IAG39_23495	COG1981	membrane
IAG39_23525	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IAG39_23535	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IAG39_23550	COG0148	phosphopyruvate hydratase activity
IAG39_23560	COG0504	CTP synthase activity
IAG39_23585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAG39_23595	COG0747	negative chemotaxis
IAG39_23600	COG4172	Belongs to the ABC transporter superfamily
IAG39_23605	COG1446	asparaginase
IAG39_23615	COG2153	protein acetylation
IAG39_23640	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IAG39_23670	COG0747	negative chemotaxis
IAG39_23685	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IAG39_23690	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
IAG39_23695	COG0697	spore germination
IAG39_23700	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IAG39_23710	COG3193	protein, possibly involved in utilization of glycolate and propanediol
IAG39_23720	COG0791	NLP P60 protein
IAG39_23730	COG0583	DNA-binding transcription factor activity
IAG39_23755	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IAG39_23775	COG0667	Aldo Keto reductase
IAG39_23785	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_23805	COG1381	Involved in DNA repair and RecF pathway recombination
IAG39_23810	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IAG39_23815	COG0571	ribonuclease III activity
IAG39_23820	COG0681	Belongs to the peptidase S26 family
IAG39_23830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IAG39_23855	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IAG39_23860	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IAG39_23865	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_23870	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IAG39_23875	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IAG39_23880	COG0416	fatty acid biosynthetic process
IAG39_23885	COG0333	Belongs to the bacterial ribosomal protein bL32 family
IAG39_23890	COG1399	metal-binding, possibly nucleic acid-binding protein
IAG39_23895	COG0424	maF-like protein
IAG39_23905	COG3023	N-Acetylmuramoyl-L-alanine amidase
IAG39_23910	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
IAG39_23915	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IAG39_23930	COG1530	ribonuclease E activity
IAG39_23945	COG2721	sulfolactate sulfo-lyase activity
IAG39_23950	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_23955	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IAG39_23960	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IAG39_23965	COG0159	tryptophan synthase activity
IAG39_23975	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IAG39_23985	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IAG39_23990	COG3228	Belongs to the MtfA family
IAG39_24000	COG0251	oxidation-reduction process
IAG39_24010	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IAG39_24025	COG2878	Part of a membrane complex involved in electron transport
IAG39_24030	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IAG39_24065	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IAG39_24085	COG1012	belongs to the aldehyde dehydrogenase family
IAG39_24090	COG2084	Dehydrogenase
IAG39_24095	COG1414	Transcriptional regulator
IAG39_24130	COG1268	BioY protein
IAG39_24135	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IAG39_24140	COG1122	ATPase activity
IAG39_24145	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IAG39_24150	COG2917	probably involved in intracellular septation
IAG39_24155	COG0271	Belongs to the BolA IbaG family
IAG39_24160	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IAG39_24165	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IAG39_24170	COG2175	clavaminate synthase activity
IAG39_24185	COG1414	Transcriptional regulator
IAG39_24190	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IAG39_24200	COG1196	nuclear chromosome segregation
IAG39_24205	COG0477	Major facilitator Superfamily
IAG39_24210	COG1573	uracil-dna glycosylase
IAG39_24215	COG1214	PFAM Peptidase M22, glycoprotease
IAG39_24230	COG0450	alkyl hydroperoxide reductase
IAG39_24235	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IAG39_24245	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
IAG39_24250	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IAG39_24255	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IAG39_24260	COG0560	Phosphoserine phosphatase
IAG39_24265	COG4774	siderophore transport
IAG39_24275	COG1007	ATP synthesis coupled electron transport
IAG39_24290	COG0713	ATP synthesis coupled electron transport
IAG39_24300	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IAG39_24305	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IAG39_24310	COG1034	ATP synthesis coupled electron transport
IAG39_24320	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
IAG39_24325	COG0649	NAD binding
IAG39_24330	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IAG39_24335	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IAG39_24340	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IAG39_24345	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IAG39_24365	COG0671	phosphoesterase, PA-phosphatase related
IAG39_24370	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IAG39_24390	COG0583	DNA-binding transcription factor activity
IAG39_24395	COG1309	transcriptional regulator
IAG39_24405	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IAG39_24420	COG1538	Outer membrane efflux protein
IAG39_24425	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IAG39_24430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IAG39_24435	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IAG39_24445	COG1309	transcriptional regulator
IAG39_24455	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IAG39_24500	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
IAG39_24510	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_24515	COG0747	negative chemotaxis
IAG39_24545	COG2354	Protein conserved in bacteria
IAG39_24550	COG3813	Protein conserved in bacteria
IAG39_24555	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
IAG39_24560	COG3604	Transcriptional regulator
IAG39_24565	COG0508	dehydrogenase complex catalyzes the overall conversion of
IAG39_24575	COG0022	dehydrogenase e1 component
IAG39_24575	COG0508	dehydrogenase complex catalyzes the overall conversion of
IAG39_24590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IAG39_24595	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IAG39_24605	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_24610	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IAG39_24620	COG1609	Transcriptional regulator
IAG39_24630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IAG39_24635	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IAG39_24640	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_24655	COG3119	arylsulfatase activity
IAG39_24675	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_24680	COG2851	Citrate transporter
IAG39_24720	COG0318	PFAM AMP-dependent synthetase and ligase
IAG39_24730	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IAG39_24775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IAG39_24780	COG0697	spore germination
IAG39_24790	COG2203	Gaf domain
IAG39_24790	COG4251	negative regulation of phosphorylation
IAG39_24790	COG5001	Diguanylate cyclase
IAG39_24790	COG3706	GGDEF domain
IAG39_24805	COG0698	ribose 5-phosphate isomerase
IAG39_24835	COG3048	D-serine ammonia-lyase activity
IAG39_24840	COG0583	DNA-binding transcription factor activity
IAG39_24845	COG1971	Probably functions as a manganese efflux pump
IAG39_24870	COG1595	DNA-templated transcription, initiation
IAG39_24895	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IAG39_24895	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IAG39_24905	COG0251	oxidation-reduction process
IAG39_24915	COG0747	negative chemotaxis
IAG39_24920	COG0601	transmembrane transport
IAG39_24925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAG39_24930	COG0444	Belongs to the ABC transporter superfamily
IAG39_24935	COG4608	Belongs to the ABC transporter superfamily
IAG39_24940	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
IAG39_24960	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IAG39_24985	COG0251	oxidation-reduction process
IAG39_25010	COG1126	abc transporter atp-binding protein
IAG39_25020	COG1176	ABC-type spermidine putrescine transport system, permease component I
IAG39_25025	COG1177	transmembrane transport
IAG39_25030	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IAG39_25035	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
IAG39_25045	COG4221	oxidoreductase activity
IAG39_25045	COG3321	synthase
IAG39_25045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAG39_25045	COG0604	alcohol dehydrogenase
IAG39_25050	COG3842	ATPase activity
IAG39_25055	COG2072	flavoprotein involved in K transport
IAG39_25075	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_25085	COG0371	Dehydrogenase
IAG39_25100	COG1960	acyl-CoA dehydrogenase activity
IAG39_25110	COG0583	DNA-binding transcription factor activity
IAG39_25190	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IAG39_25225	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_25235	COG5383	Protein conserved in bacteria
IAG39_25240	COG0583	DNA-binding transcription factor activity
IAG39_25265	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IAG39_25275	COG0647	UMP catabolic process
IAG39_25280	COG1737	Transcriptional regulator
IAG39_25285	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IAG39_25290	COG0149	triose-phosphate isomerase activity
IAG39_25295	COG3321	synthase
IAG39_25295	COG0604	alcohol dehydrogenase
IAG39_25305	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IAG39_25310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IAG39_25315	COG2010	Cytochrome c
IAG39_25325	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IAG39_25325	COG1648	precorrin-2 dehydrogenase activity
IAG39_25335	COG0535	radical SAM domain protein
IAG39_25350	COG1522	sequence-specific DNA binding
IAG39_25360	COG2010	Cytochrome c
IAG39_25365	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IAG39_25365	COG1648	precorrin-2 dehydrogenase activity
IAG39_25375	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IAG39_25385	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IAG39_25425	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IAG39_25435	COG1185	polyribonucleotide nucleotidyltransferase activity
IAG39_25440	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IAG39_25450	COG1183	phosphatidylcholine synthase activity
IAG39_25455	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IAG39_25460	COG0440	acetolactate synthase activity
IAG39_25465	COG0028	Belongs to the TPP enzyme family
IAG39_25470	COG1289	transmembrane transporter activity
IAG39_25475	COG3022	response to hydroperoxide
IAG39_25480	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_25495	COG0840	transmembrane signaling receptor activity
IAG39_25500	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IAG39_25505	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IAG39_25510	COG0477	Major facilitator Superfamily
IAG39_25520	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IAG39_25530	COG4948	Mandelate Racemase Muconate Lactonizing
IAG39_25565	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IAG39_25570	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IAG39_25575	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IAG39_25590	COG0601	transmembrane transport
IAG39_25610	COG1737	Transcriptional regulator
IAG39_25615	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
IAG39_25625	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IAG39_25630	COG1674	ftsk spoiiie
IAG39_25635	COG0492	ferredoxin-NADP+ reductase activity
IAG39_25640	COG1193	negative regulation of DNA recombination
IAG39_25660	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IAG39_25675	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IAG39_25680	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IAG39_25685	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
IAG39_25690	COG2205	protein histidine kinase activity
IAG39_25695	COG0745	RESPONSE REGULATOR receiver
IAG39_25710	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IAG39_25715	COG0840	transmembrane signaling receptor activity
IAG39_25740	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IAG39_25760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IAG39_25765	COG0612	Peptidase, M16
IAG39_25775	COG0484	heat shock protein binding
IAG39_25780	COG0443	Heat shock 70 kDa protein
IAG39_25790	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IAG39_25800	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
IAG39_25805	COG1420	regulation of RNA biosynthetic process
IAG39_25815	COG0497	DNA recombination
IAG39_25820	COG0735	belongs to the Fur family
IAG39_25825	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IAG39_25835	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IAG39_25855	COG0753	catalase activity
IAG39_25865	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_25870	COG0583	DNA-binding transcription factor activity
IAG39_25895	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IAG39_25900	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IAG39_25910	COG1053	succinate dehydrogenase
IAG39_25945	COG0784	Response regulator, receiver
IAG39_25945	COG2205	protein histidine kinase activity
IAG39_25950	COG2202	Pas domain
IAG39_25950	COG2200	EAL domain
IAG39_25950	COG2199	diguanylate cyclase activity
IAG39_25955	COG0784	Response regulator, receiver
IAG39_25955	COG2205	protein histidine kinase activity
IAG39_26020	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IAG39_26045	COG0583	DNA-binding transcription factor activity
IAG39_26055	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IAG39_26060	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
IAG39_26065	COG0167	dihydroorotate dehydrogenase activity
IAG39_26080	COG1414	Transcriptional regulator
IAG39_26085	COG1546	Belongs to the CinA family
IAG39_26085	COG1058	Belongs to the CinA family
IAG39_26100	COG0513	Belongs to the DEAD box helicase family
IAG39_26130	COG0429	hydrolase of the alpha beta-hydrolase fold
IAG39_26135	COG4783	chaperone-mediated protein folding
IAG39_26145	COG1113	amino acid transport
IAG39_26150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IAG39_26150	COG2022	thiamine diphosphate biosynthetic process
IAG39_26165	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IAG39_26170	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IAG39_26190	COG0006	proline dipeptidase activity
IAG39_26200	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IAG39_26220	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
IAG39_26225	COG0632	four-way junction helicase activity
IAG39_26230	COG1090	epimerase
IAG39_26240	COG2255	four-way junction helicase activity
IAG39_26260	COG0514	ATP-dependent DNA helicase (RecQ)
IAG39_26270	COG1271	oxidase subunit
IAG39_26275	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IAG39_26280	COG0850	regulation of cytokinetic process
IAG39_26285	COG2894	cell division
IAG39_26290	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
IAG39_26305	COG0488	(ABC) transporter
IAG39_26325	COG4608	Belongs to the ABC transporter superfamily
IAG39_26330	COG0444	Belongs to the ABC transporter superfamily
IAG39_26335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAG39_26340	COG0601	transmembrane transport
IAG39_26345	COG0747	negative chemotaxis
IAG39_26370	COG4638	Rieske (2fe-2S)
IAG39_26395	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
IAG39_26400	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_26425	COG1216	Glycosyl transferase, family 2
IAG39_26425	COG0463	Glycosyl transferase, family 2
IAG39_26450	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IAG39_26485	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IAG39_26490	COG1538	Outer membrane efflux protein
IAG39_26495	COG0577	efflux transmembrane transporter activity
IAG39_26495	COG1136	(ABC) transporter
IAG39_26500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IAG39_26515	COG0259	pyridoxamine-phosphate oxidase activity
IAG39_26520	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IAG39_26525	COG0579	oxidoreductase
IAG39_26535	COG0659	secondary active sulfate transmembrane transporter activity
IAG39_26540	COG0583	DNA-binding transcription factor activity
IAG39_26545	COG1960	acyl-CoA dehydrogenase activity
IAG39_26550	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_26555	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IAG39_26560	COG0405	Gamma-glutamyltransferase
IAG39_26570	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_26580	COG0114	fumarate hydratase activity
IAG39_26585	COG0802	atpase or kinase
IAG39_26590	COG0860	N-Acetylmuramoyl-L-alanine amidase
IAG39_26595	COG0586	Pfam SNARE associated Golgi protein
IAG39_26600	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IAG39_26605	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IAG39_26610	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IAG39_26625	COG0617	tRNA 3'-terminal CCA addition
IAG39_26635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IAG39_26640	COG2301	Belongs to the HpcH HpaI aldolase family
IAG39_26645	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IAG39_26650	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
IAG39_26660	COG1024	Enoyl-CoA hydratase
IAG39_26665	COG1960	acyl-CoA dehydrogenase activity
IAG39_26670	COG1960	acyl-CoA dehydrogenase activity
IAG39_26685	COG0318	PFAM AMP-dependent synthetase and ligase
IAG39_26705	COG0583	DNA-binding transcription factor activity
IAG39_26710	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_26715	COG2030	dehydratase
IAG39_26720	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IAG39_26730	COG1024	Enoyl-CoA hydratase
IAG39_26735	COG0752	glycyl-tRNA synthetase alpha subunit
IAG39_26740	COG0751	glycine-tRNA ligase activity
IAG39_26745	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IAG39_26750	COG0204	Acyl-transferase
IAG39_26770	COG0242	peptide deformylase activity
IAG39_26775	COG1960	acyl-CoA dehydrogenase activity
IAG39_26780	COG0700	Nucleoside recognition
IAG39_26785	COG0469	pyruvate kinase activity
IAG39_26790	COG1929	Belongs to the glycerate kinase type-1 family
IAG39_26795	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IAG39_26800	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IAG39_26815	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IAG39_26825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IAG39_26840	COG2154	pterin-4-alpha-carbinolamine dehydratase
IAG39_26860	COG0436	Aminotransferase
IAG39_26870	COG1522	sequence-specific DNA binding
IAG39_26880	COG0583	DNA-binding transcription factor activity
IAG39_26885	COG1126	abc transporter atp-binding protein
IAG39_26890	COG0765	amino acid transport
IAG39_26895	COG0765	amino acid transport
IAG39_26900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAG39_26920	COG0583	DNA-binding transcription factor activity
IAG39_26935	COG0626	cystathionine gamma-synthase activity
IAG39_26960	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_26975	COG2982	Protein involved in outer membrane biogenesis
IAG39_26980	COG1368	sulfuric ester hydrolase activity
IAG39_26985	COG2818	Glycosylase
IAG39_27005	COG0735	belongs to the Fur family
IAG39_27030	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_27090	COG3706	GGDEF domain
IAG39_27095	COG0840	transmembrane signaling receptor activity
IAG39_27110	COG2011	ABC-type metal ion transport system permease component
IAG39_27115	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IAG39_27120	COG1501	Belongs to the glycosyl hydrolase 31 family
IAG39_27125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IAG39_27125	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
IAG39_27135	COG0318	PFAM AMP-dependent synthetase and ligase
IAG39_27140	COG1473	amidohydrolase
IAG39_27150	COG2855	membrane
IAG39_27160	COG2239	Acts as a magnesium transporter
IAG39_27175	COG1522	sequence-specific DNA binding
IAG39_27180	COG0300	oxidoreductase activity
IAG39_27190	COG0028	Belongs to the TPP enzyme family
IAG39_27195	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_27210	COG0653	protein targeting
IAG39_27215	COG0739	heme binding
IAG39_27225	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
IAG39_27230	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IAG39_27240	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IAG39_27245	COG1181	Belongs to the D-alanine--D-alanine ligase family
IAG39_27250	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IAG39_27255	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IAG39_27265	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IAG39_27270	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IAG39_27275	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IAG39_27285	COG3116	cell division
IAG39_27290	COG0275	rRNA processing
IAG39_27295	COG2001	Belongs to the MraZ family
IAG39_27305	COG0488	(ABC) transporter
IAG39_27310	COG0418	dihydroorotase activity
IAG39_27315	COG1473	amidohydrolase
IAG39_27375	COG1522	sequence-specific DNA binding
IAG39_27385	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IAG39_27390	COG4654	Cytochrome c, class I
IAG39_27395	COG0129	dihydroxy-acid dehydratase activity
IAG39_27435	COG0405	Gamma-glutamyltransferase
IAG39_27440	COG2084	Dehydrogenase
IAG39_27445	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IAG39_27455	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IAG39_27490	COG0824	Thioesterase
IAG39_27495	COG0811	peptide transport
IAG39_27500	COG0848	biopolymer transport protein
IAG39_27510	COG0823	Involved in the tonB-independent uptake of proteins
IAG39_27525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IAG39_27530	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
IAG39_27540	COG0596	Alpha beta hydrolase
IAG39_27540	COG0508	dehydrogenase complex catalyzes the overall conversion of
IAG39_27545	COG1522	sequence-specific DNA binding
IAG39_27555	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IAG39_27570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IAG39_27575	COG0697	spore germination
IAG39_27585	COG1346	cytolysis
IAG39_27590	COG1380	Effector of murein hydrolase LrgA
IAG39_27595	COG0583	DNA-binding transcription factor activity
IAG39_27605	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IAG39_27610	COG1129	ABC transporter
IAG39_27645	COG0583	DNA-binding transcription factor activity
IAG39_27660	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IAG39_27665	COG0463	Glycosyl transferase, family 2
IAG39_27675	COG0786	glutamate:sodium symporter activity
IAG39_27690	COG1671	Belongs to the UPF0178 family
IAG39_27710	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IAG39_27715	COG1566	PFAM secretion protein HlyD family protein
IAG39_27720	COG0328	RNA-DNA hybrid ribonuclease activity
IAG39_27725	COG2226	methyltransferase
IAG39_27730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IAG39_27735	COG1388	LysM domain
IAG39_27735	COG0741	lytic transglycosylase activity
IAG39_27740	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IAG39_27745	COG3608	succinylglutamate desuccinylase aspartoacylase
IAG39_27770	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_27805	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_27825	COG2719	SpoVR family
IAG39_27830	COG2718	Belongs to the UPF0229 family
IAG39_27835	COG2766	serine protein kinase
IAG39_27850	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IAG39_27850	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IAG39_27860	COG2207	Transcriptional regulator
IAG39_27865	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IAG39_27870	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IAG39_27880	COG1881	PFAM PEBP family protein
IAG39_27885	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IAG39_27900	COG0316	Belongs to the HesB IscA family
IAG39_27910	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IAG39_27915	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IAG39_27920	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IAG39_27935	COG4177	L-phenylalanine transmembrane transporter activity
IAG39_27940	COG0559	Belongs to the binding-protein-dependent transport system permease family
IAG39_27950	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IAG39_27955	COG0312	modulator of DNA gyrase
IAG39_27960	COG3028	Belongs to the UPF0307 family
IAG39_27975	COG1116	anion transmembrane transporter activity
IAG39_27980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IAG39_27985	COG1335	isochorismatase
IAG39_27990	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IAG39_27990	COG0045	succinate-CoA ligase (ADP-forming) activity
IAG39_27990	COG1042	CoA-binding domain protein
IAG39_27995	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IAG39_28010	COG0583	DNA-binding transcription factor activity
IAG39_28020	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_28025	COG1522	sequence-specific DNA binding
IAG39_28050	COG0762	integral membrane protein
IAG39_28055	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IAG39_28060	COG1696	Membrane protein involved in D-alanine export
IAG39_28085	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
IAG39_28085	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
IAG39_28095	COG2264	protein methyltransferase activity
IAG39_28100	COG0439	Biotin carboxylase
IAG39_28105	COG0511	ligase activity, forming carbon-carbon bonds
IAG39_28110	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
IAG39_28115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IAG39_28120	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IAG39_28125	COG3150	esterase
IAG39_28130	COG0557	exoribonuclease II activity
IAG39_28155	COG0625	glutathione transferase activity
IAG39_28160	COG0077	Prephenate dehydratase
IAG39_28160	COG1605	Chorismate mutase
IAG39_28170	COG2081	HI0933 family
IAG39_28175	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IAG39_28185	COG0559	Belongs to the binding-protein-dependent transport system permease family
IAG39_28195	COG1129	ABC transporter
IAG39_28215	COG1126	abc transporter atp-binding protein
IAG39_28220	COG0765	amino acid transport
IAG39_28225	COG4597	amino acid ABC transporter
IAG39_28230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAG39_28235	COG2884	Cell division ATP-binding protein ftsE
IAG39_28240	COG2177	Part of the ABC transporter FtsEX involved in
IAG39_28255	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
IAG39_28265	COG2186	Transcriptional regulator
IAG39_28275	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IAG39_28305	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_28310	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IAG39_28320	COG0508	dehydrogenase complex catalyzes the overall conversion of
IAG39_28325	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IAG39_28330	COG0583	DNA-binding transcription factor activity
IAG39_28355	COG1024	Enoyl-CoA hydratase
IAG39_28360	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_28370	COG0129	dihydroxy-acid dehydratase activity
IAG39_28395	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IAG39_28400	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IAG39_28405	COG1250	3-hydroxyacyl-CoA dehydrogenase
IAG39_28410	COG2031	fatty acid transporter
IAG39_28415	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_28420	COG1414	Transcriptional regulator
IAG39_28430	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IAG39_28435	COG4829	muconolactone delta-isomerase
IAG39_28445	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IAG39_28460	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IAG39_28465	COG2890	protein-(glutamine-N5) methyltransferase activity
IAG39_28470	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IAG39_28495	COG3264	Mechanosensitive ion channel
IAG39_28495	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
IAG39_28505	COG1132	(ABC) transporter
IAG39_28520	COG2217	Heavy metal translocating P-type atpase
IAG39_28525	COG1595	DNA-templated transcription, initiation
IAG39_28540	COG1522	sequence-specific DNA binding
IAG39_28560	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_28565	COG3622	Belongs to the hyi family
IAG39_28570	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IAG39_28575	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IAG39_28600	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
IAG39_28605	COG1012	belongs to the aldehyde dehydrogenase family
IAG39_28610	COG0583	DNA-binding transcription factor activity
IAG39_28620	COG2186	Transcriptional regulator
IAG39_28625	COG3395	kinase activity
IAG39_28630	COG2084	Dehydrogenase
IAG39_28635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IAG39_28640	COG3622	Belongs to the hyi family
IAG39_28645	COG0235	Class ii aldolase
IAG39_28655	COG2084	Dehydrogenase
IAG39_28660	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IAG39_28665	COG0683	leucine binding
IAG39_28690	COG2188	Transcriptional regulator
IAG39_28705	COG0523	cobalamin synthesis protein
IAG39_28710	COG1335	isochorismatase
IAG39_28715	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IAG39_28720	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IAG39_28725	COG1802	Transcriptional regulator
IAG39_28730	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IAG39_28740	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_28750	COG4774	siderophore transport
IAG39_28770	COG4585	Histidine kinase
IAG39_28790	COG2197	response regulator
IAG39_28795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAG39_28795	COG2205	protein histidine kinase activity
IAG39_28800	COG2198	Histidine kinase
IAG39_28800	COG2205	protein histidine kinase activity
IAG39_28800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAG39_28800	COG0784	Response regulator, receiver
IAG39_28805	COG3539	Fimbrial protein
IAG39_28835	COG3121	Chaperone
IAG39_28840	COG3188	usher protein
IAG39_28845	COG3121	Chaperone
IAG39_28870	COG0784	Response regulator, receiver
IAG39_28870	COG2205	protein histidine kinase activity
IAG39_28875	COG3119	arylsulfatase activity
IAG39_28890	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IAG39_28950	COG3451	type IV secretory pathway VirB4
IAG39_28985	COG2948	multi-organism process
IAG39_29010	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IAG39_29055	COG3133	Outer membrane lipoprotein
IAG39_29115	COG3593	DNA synthesis involved in DNA repair
IAG39_29145	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IAG39_29155	COG0583	DNA-binding transcription factor activity
IAG39_29200	COG1695	Transcriptional regulator
IAG39_29215	COG0659	secondary active sulfate transmembrane transporter activity
IAG39_29230	COG0551	DNA topoisomerase type I activity
IAG39_29230	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IAG39_29285	COG0489	protein tyrosine kinase activity
IAG39_29295	COG0142	geranyltranstransferase activity
IAG39_29305	COG1414	Transcriptional regulator
IAG39_29310	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IAG39_29315	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IAG39_29320	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IAG39_29325	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IAG39_29350	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IAG39_29365	COG2186	Transcriptional regulator
IAG39_29375	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IAG39_29380	COG0793	Belongs to the peptidase S41A family
IAG39_29385	COG4942	peptidase
IAG39_29390	COG0588	phosphoglycerate mutase activity
IAG39_29395	COG1054	Belongs to the UPF0176 family
IAG39_29400	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IAG39_29405	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
IAG39_29410	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
IAG39_29420	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IAG39_29425	COG1040	competence protein
IAG39_29430	COG2226	methyltransferase
IAG39_29435	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
IAG39_29440	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IAG39_29445	COG0569	domain protein
IAG39_29450	COG2204	response regulator
IAG39_29455	COG5000	phosphorelay sensor kinase activity
IAG39_29465	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IAG39_29465	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IAG39_29470	COG1280	lysine exporter protein (LysE YggA)
IAG39_29480	COG1024	Enoyl-CoA hydratase
IAG39_29485	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IAG39_29485	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IAG39_29490	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IAG39_29490	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
IAG39_29495	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IAG39_29505	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_29525	COG1012	belongs to the aldehyde dehydrogenase family
IAG39_29535	COG2096	Adenosyltransferase
IAG39_29545	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IAG39_29555	COG1733	regulation of RNA biosynthetic process
IAG39_29575	COG0546	phosphoglycolate phosphatase activity
IAG39_29585	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IAG39_29590	COG0242	peptide deformylase activity
IAG39_29595	COG0758	DNA mediated transformation
IAG39_29610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IAG39_29615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IAG39_29620	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IAG39_29625	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_29635	COG1238	metal cluster binding
IAG39_29640	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IAG39_29645	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IAG39_29660	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IAG39_29665	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IAG39_29670	COG4988	ABC transporter
IAG39_29680	COG1294	oxidase, subunit
IAG39_29685	COG1271	oxidase subunit
IAG39_29695	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IAG39_29705	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IAG39_29720	COG1137	ATPase activity
IAG39_29725	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IAG39_29735	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IAG39_29740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IAG39_29755	COG1660	Displays ATPase and GTPase activities
IAG39_29765	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IAG39_29780	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
IAG39_29785	COG2823	Periplasmic or secreted lipoprotein
IAG39_29790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IAG39_29800	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IAG39_29810	COG1309	transcriptional regulator
IAG39_29815	COG0471	metal ion transport
IAG39_29820	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
IAG39_29825	COG0772	Belongs to the SEDS family
IAG39_29830	COG0768	penicillin binding
IAG39_29840	COG1792	Involved in formation and maintenance of cell shape
IAG39_29845	COG1077	Cell shape determining protein MreB Mrl
IAG39_29850	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IAG39_29855	COG0154	amidase activity
IAG39_29860	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IAG39_29875	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IAG39_29880	COG0708	Exodeoxyribonuclease III
IAG39_29890	COG1280	lysine exporter protein (LysE YggA)
IAG39_29895	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IAG39_29905	COG0583	DNA-binding transcription factor activity
IAG39_29920	COG0583	DNA-binding transcription factor activity
IAG39_29945	COG1764	response to oxidative stress
IAG39_29950	COG1846	Transcriptional regulator
IAG39_29995	COG0730	response to heat
IAG39_30015	COG0640	Transcriptional regulator
IAG39_30030	COG0456	acetyltransferase
IAG39_30040	COG0297	glycogen (starch) synthase activity
IAG39_30055	COG3189	MarR family transcriptional regulator
IAG39_30060	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IAG39_30065	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IAG39_30070	COG0513	Belongs to the DEAD box helicase family
IAG39_30090	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IAG39_30095	COG2308	Evidence 4 Homologs of previously reported genes of
IAG39_30105	COG1305	Transglutaminase-like
IAG39_30125	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IAG39_30130	COG1950	PFAM Membrane protein of
IAG39_30135	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IAG39_30140	COG0438	transferase activity, transferring glycosyl groups
IAG39_30150	COG0596	Alpha beta hydrolase
IAG39_30155	COG0066	3-isopropylmalate dehydratase activity
IAG39_30165	COG3181	Tripartite tricarboxylate transporter family receptor
IAG39_30170	COG0583	DNA-binding transcription factor activity
IAG39_30180	COG0477	Major facilitator Superfamily
IAG39_30185	COG0154	amidase activity
IAG39_30190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IAG39_30205	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IAG39_30215	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IAG39_30220	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
IAG39_30245	COG0735	belongs to the Fur family
IAG39_30250	COG0523	cobalamin synthesis protein
IAG39_30260	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IAG39_30265	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IAG39_30275	COG2096	Adenosyltransferase
IAG39_30300	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IAG39_30305	COG1609	Transcriptional regulator
IAG39_30315	COG0321	lipoyl(octanoyl) transferase activity
IAG39_30330	COG1686	Belongs to the peptidase S11 family
IAG39_30355	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IAG39_30365	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IAG39_30380	COG0859	PFAM glycosyl transferase family 9
IAG39_30385	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IAG39_30390	COG1216	Glycosyl transferase, family 2
IAG39_30395	COG1216	Glycosyl transferase, family 2
IAG39_30395	COG0438	transferase activity, transferring glycosyl groups
IAG39_30400	COG0438	transferase activity, transferring glycosyl groups
IAG39_30405	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IAG39_30465	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IAG39_30480	COG2814	Major facilitator Superfamily
IAG39_30485	COG0697	spore germination
IAG39_30495	COG3568	Endonuclease Exonuclease Phosphatase
IAG39_30500	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IAG39_30530	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IAG39_30545	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IAG39_30560	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IAG39_30565	COG1956	GAF domain-containing protein
IAG39_30570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IAG39_30595	COG2186	Transcriptional regulator
IAG39_30640	COG2814	Major facilitator Superfamily
IAG39_30650	COG0625	glutathione transferase activity
IAG39_30655	COG0583	DNA-binding transcription factor activity
IAG39_30665	COG1473	amidohydrolase
IAG39_30670	COG0232	Belongs to the dGTPase family. Type 2 subfamily
IAG39_30675	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IAG39_30680	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IAG39_30690	COG1965	Belongs to the frataxin family
IAG39_30700	COG0019	diaminopimelate decarboxylase activity
IAG39_30820	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IAG39_30825	COG1333	cytochrome c biogenesis protein
IAG39_30835	COG0218	Necessary for normal cell division and for the maintenance of normal septation
IAG39_30870	COG1028	Short-chain dehydrogenase reductase Sdr
IAG39_30875	COG1053	succinate dehydrogenase
IAG39_30885	COG4232	protein-disulfide reductase activity
IAG39_30890	COG1324	tolerance protein
IAG39_30895	COG0537	adenosine 5'-monophosphoramidase activity
IAG39_30900	COG0203	ribosomal protein L17
IAG39_30905	COG0202	RNA polymerase activity
IAG39_30910	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IAG39_30915	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IAG39_30920	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IAG39_30925	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IAG39_30930	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IAG39_30935	COG0201	protein transport
IAG39_30940	COG0200	Binds to the 23S rRNA
IAG39_30945	COG1841	ribosomal large subunit assembly
IAG39_30950	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IAG39_30955	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IAG39_30960	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IAG39_30965	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IAG39_30970	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IAG39_30975	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IAG39_30980	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IAG39_30985	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IAG39_31000	COG2207	Transcriptional regulator
IAG39_31020	COG1126	abc transporter atp-binding protein
IAG39_31025	COG4177	L-phenylalanine transmembrane transporter activity
IAG39_31045	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IAG39_31050	COG0255	Belongs to the universal ribosomal protein uL29 family
IAG39_31055	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IAG39_31060	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IAG39_31065	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IAG39_31070	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IAG39_31075	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IAG39_31080	COG0089	rRNA binding
IAG39_31090	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IAG39_31095	COG0051	transcription antitermination factor activity, RNA binding
IAG39_31100	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IAG39_31105	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IAG39_31110	COG0049	tRNA binding
IAG39_31115	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IAG39_31135	COG5002	protein histidine kinase activity
IAG39_31150	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IAG39_31155	COG0085	RNA polymerase activity
IAG39_31160	COG0222	ribosome binding
IAG39_31165	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IAG39_31170	COG0081	regulation of translation
IAG39_31175	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IAG39_31185	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IAG39_31195	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IAG39_31235	COG1840	ABC-type Fe3 transport system, periplasmic component
IAG39_31240	COG3842	ATPase activity
IAG39_31250	COG1349	DNA-binding transcription factor activity
IAG39_31275	COG0583	DNA-binding transcription factor activity
IAG39_31280	COG0252	asparaginase activity
IAG39_31285	COG1475	DNA binding
IAG39_31295	COG1192	Involved in chromosome partitioning
IAG39_31300	COG0357	Ribosomal RNA small subunit methyltransferase G
IAG39_31305	COG0445	tRNA wobble uridine modification
IAG39_31315	COG1278	Cold shock
IAG39_31320	COG3180	Ammonia monooxygenase
IAG39_31325	COG0436	Aminotransferase
IAG39_31345	COG0642	Histidine kinase
IAG39_31355	COG0038	chloride channel
IAG39_31380	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IAG39_31390	COG0601	transmembrane transport
IAG39_31395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IAG39_31400	COG0444	Belongs to the ABC transporter superfamily
IAG39_31405	COG4608	Belongs to the ABC transporter superfamily
IAG39_31410	COG1473	amidohydrolase
IAG39_31415	COG2175	clavaminate synthase activity
IAG39_31425	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IAG39_31435	COG0753	catalase activity
IAG39_31440	COG0706	membrane insertase activity
IAG39_31445	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
IAG39_31450	COG0594	ribonuclease P activity
IAG39_31455	COG0230	Belongs to the bacterial ribosomal protein bL34 family