locus-tag	class	description
HPS43_00040	ENOG4108S8N	class II Aldolase
HPS43_00070	ENOG4108YXQ	IS66 Orf2 family protein
HPS43_00135	ENOG4108P8G	outer membrane autotransporter barrel
HPS43_00200	ENOG4108UKI	Enoyl-CoA hydratase
HPS43_00215	ENOG4105CC0	LysR family Transcriptional regulator
HPS43_00230	ENOG4105BZU	Histidine kinase
HPS43_00245	ENOG41061WM	D-Alanyl-D-Alanine
HPS43_00255	ENOG4105EXC	Acyl-transferase
HPS43_00270	ENOG4105MI0	Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3- dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2- hydroxy-6-ketononatrienedioate, respectively (By similarity)
HPS43_00300	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HPS43_00315	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HPS43_00320	ENOG41069H7	transport system small permease component
HPS43_00325	ENOG4105CH5	extracellular solute-binding protein, family 7
HPS43_00340	ENOG4105ETE	Transcriptional regulator (LacI family
HPS43_00345	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HPS43_00350	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HPS43_00360	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
HPS43_00375	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
HPS43_00380	ENOG4105CSW	GntR family transcriptional regulator
HPS43_00385	ENOG4105CXN	decarboxylase
HPS43_00395	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
HPS43_00400	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HPS43_00415	ENOG4105CF7	AraC family transcriptional regulator
HPS43_00420	ENOG4107U9B	transcriptional regulator
HPS43_00435	ENOG4105JAB	phenazine biosynthesis protein, phzf family
HPS43_00490	ENOG4105D64	Mechanosensitive ion channel
HPS43_00500	ENOG4107QP8	phosphohexose isomerase
HPS43_00535	ENOG4105X23	Endonuclease Exonuclease phosphatase
HPS43_00540	ENOG4105DZQ	phospholipase D Transphosphatidylase
HPS43_00545	ENOG4107UXM	Membrane
HPS43_00550	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
HPS43_00555	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
HPS43_00560	ENOG4105CG3	alpha amylase, catalytic region
HPS43_00575	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
HPS43_00580	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
HPS43_00590	ENOG4105C85	amino acid
HPS43_00605	ENOG4105DQE	DNA ligase
HPS43_00610	ENOG4105FDF	Could be involved in DNA repair (By similarity)
HPS43_00615	ENOG4105CEV	competence damage-inducible protein
HPS43_00625	ENOG4105BZU	Histidine kinase
HPS43_00645	ENOG4107S4Y	M20 DapE family protein YgeY
HPS43_00665	ENOG4105CSH	Transporter
HPS43_00680	ENOG4105D05	Receptor
HPS43_00695	ENOG4108W0P	ABC transporter
HPS43_00700	ENOG4105EHG	Permease protein
HPS43_00720	ENOG4108UAJ	Transcriptional regulator
HPS43_00750	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
HPS43_00765	ENOG4105J4Q	Transcriptional regulator
HPS43_00770	ENOG4105ERH	Fumarylacetoacetate hydrolase
HPS43_00775	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
HPS43_00785	ENOG4105CTX	dehydratase
HPS43_00795	ENOG4105DRP	amino acid AbC transporter
HPS43_00805	ENOG4105EAB	amino acid AbC transporter
HPS43_00810	ENOG4105DIA	mandelate racemase muconate lactonizing
HPS43_00820	ENOG4105E2X	shikimate dehydrogenase
HPS43_00825	ENOG4108IUS	Transketolase
HPS43_00830	ENOG4108HHA	Transketolase
HPS43_00835	ENOG4108WYP	Transcriptional regulator
HPS43_00840	ENOG4105DCT	glycerol dehydrogenase
HPS43_00845	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
HPS43_00850	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
HPS43_00855	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HPS43_00865	ENOG4105C32	Amino acid ABC transporter (Permease)
HPS43_00870	ENOG4105C0Z	ABC transporter
HPS43_00875	ENOG4108IV0	ABC, transporter
HPS43_00885	ENOG4105CHR	reductase
HPS43_00900	ENOG4105JQN	Transcriptional regulator
HPS43_00915	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
HPS43_00920	ENOG4105HEI	LysR family (Transcriptional regulator
HPS43_00925	ENOG4107QM5	aconitate hydratase
HPS43_00930	ENOG4105UYK	outer membrane protein a
HPS43_00945	ENOG4105CW7	secretion protein, HlyD family
HPS43_00950	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HPS43_00960	ENOG4105W7K	Transcriptional regulator
HPS43_00965	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
HPS43_00980	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HPS43_00995	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HPS43_01065	ENOG4105BZU	Histidine kinase
HPS43_01085	ENOG4108JQ6	ABC transporter
HPS43_01090	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HPS43_01110	ENOG4105D7N	magnesium and cobalt transport protein CorA
HPS43_01130	ENOG4108JPW	Aminotransferase
HPS43_01135	ENOG4105C26	Dehydrogenase
HPS43_01140	ENOG4105ECY	inositol monophosphatase
HPS43_01145	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
HPS43_01150	ENOG4105D7W	serine acetyltransferase
HPS43_01155	ENOG4105CMR	udp-glucose 4-epimerase
HPS43_01160	ENOG4107QP8	phosphohexose isomerase
HPS43_01165	ENOG4107QKV	phosphomannomutase
HPS43_01180	ENOG4105D3Q	Sugar transferase
HPS43_01185	ENOG4105FGF	GDP-mannose mannosyl hydrolase
HPS43_01190	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
HPS43_01205	ENOG4105C30	Nad-dependent epimerase dehydratase
HPS43_01225	ENOG4107T8Q	Glycosyl transferase (Group 1
HPS43_01230	ENOG4106WTF	Glycosyl transferase, family 2
HPS43_01235	ENOG4108Z90	colanic acid biosynthesis acetyltransferase wcaF
HPS43_01240	ENOG4106CD9	glycosyl transferase group 1
HPS43_01245	ENOG4105WH1	Two component transcriptional regulator luxr family
HPS43_01250	ENOG4105WH1	Two component transcriptional regulator luxr family
HPS43_01260	ENOG4108XG4	DNA-binding transcriptional regulator
HPS43_01265	ENOG4107QPN	acyl-Coa dehydrogenase
HPS43_01275	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HPS43_01290	ENOG4105CHU	acetyl-coa acetyltransferase
HPS43_01305	ENOG4105CEY	Amp-dependent synthetase and ligase
HPS43_01325	ENOG4105BZ1	(ABC) transporter
HPS43_01330	ENOG4105CAX	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system (By similarity)
HPS43_01360	ENOG4105E39	Enoyl-CoA hydratase
HPS43_01370	ENOG4105J4Q	Transcriptional regulator
HPS43_01375	ENOG4108T2C	cysteine dioxygenase type I
HPS43_01380	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
HPS43_01400	ENOG4105HEI	LysR family (Transcriptional regulator
HPS43_01430	ENOG4108IJ6	ABC transporter
HPS43_01435	ENOG4108RZE	Tetr family transcriptional regulator
HPS43_01450	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
HPS43_01460	ENOG4105BZU	Histidine kinase
HPS43_01465	ENOG4105BZU	Histidine kinase
HPS43_01470	ENOG4105BZU	Histidine kinase
HPS43_01490	ENOG4105NQN	cytochrome C
HPS43_01505	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
HPS43_01525	ENOG4105C58	cytochrome c oxidase accessory protein ccog
HPS43_01540	ENOG4105CFH	Aspartokinase
HPS43_01545	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HPS43_01550	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
HPS43_01560	ENOG4105C8N	cysteinyl-tRNA synthetase
HPS43_01575	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
HPS43_01580	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
HPS43_01585	ENOG4105EE5	Membrane protein terC
HPS43_01595	ENOG4105HEE	Binding Domain protein
HPS43_01600	ENOG4105EQJ	Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide (By similarity)
HPS43_01610	ENOG4105CIG	ABC transporter
HPS43_01615	ENOG4108T0W	nitrous oxide maturation protein NosY
HPS43_01625	ENOG4105CJ2	(LipO)protein
HPS43_01630	ENOG4105DFS	Conserved Protein
HPS43_01635	ENOG4105ECY	inositol monophosphatase
HPS43_01655	ENOG4105D64	Mechanosensitive ion channel
HPS43_01695	ENOG4105GVF	(ABC) transporter
HPS43_01705	ENOG4108IY8	ABC, transporter
HPS43_01740	ENOG4105E1F	short-chain dehydrogenase reductase
HPS43_01750	ENOG4105WKW	Pfam:DUF1458
HPS43_01760	ENOG4105CC0	LysR family Transcriptional regulator
HPS43_01765	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
HPS43_01825	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
HPS43_01830	ENOG4105EZE	Cupin 4 family protein
HPS43_01840	ENOG4105GJM	(LipO)protein
HPS43_01845	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HPS43_01850	ENOG4108Z4T	Peptidase M50
HPS43_01855	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
HPS43_01860	ENOG4105CGZ	zinc metallopeptidase
HPS43_01920	ENOG4108Z7R	Chaperone CsaA
HPS43_01925	ENOG4105BZV	Phosphoadenosine phosphosulfate reductase
HPS43_01935	ENOG4105GTN	ParB Domain Protein Nuclease
HPS43_01940	ENOG4105DHQ	Histidine kinase
HPS43_01945	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HPS43_01970	ENOG4108TTM	chaperone
HPS43_01975	ENOG4105C8Q	Methyl-accepting chemotaxis
HPS43_02015	ENOG4105BZP	glycoside hydrolase 15-related
HPS43_02025	ENOG4105I03	Flagellin
HPS43_02030	ENOG4105C8Q	Methyl-accepting chemotaxis
HPS43_02040	ENOG4108NIW	Leucine export protein LeuE
HPS43_02055	ENOG4105DZQ	phospholipase D Transphosphatidylase
HPS43_02065	ENOG4106HBX	Transcriptional Regulator AraC Family
HPS43_02075	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HPS43_02090	ENOG4107XBN	GntR Family Transcriptional Regulator
HPS43_02100	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HPS43_02105	ENOG4105C0H	protease
HPS43_02135	ENOG4105E0F	Histidine kinase
HPS43_02140	ENOG4108ZHJ	Organic hydroperoxide resistance protein
HPS43_02155	ENOG4108KF1	Membrane
HPS43_02160	ENOG4107SQD	Transcriptional regulator, GntR family
HPS43_02165	ENOG4105RHY	Pfam:UPF0157
HPS43_02225	ENOG4105CJP	fad dependent oxidoreductase
HPS43_02230	ENOG4105DRP	amino acid AbC transporter
HPS43_02240	ENOG4105EAB	amino acid AbC transporter
HPS43_02250	ENOG4105C26	Dehydrogenase
HPS43_02270	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
HPS43_02300	ENOG4105C58	cytochrome c oxidase accessory protein ccog
HPS43_02320	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
HPS43_02335	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HPS43_02340	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HPS43_02350	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
HPS43_02355	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
HPS43_02375	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
HPS43_02380	ENOG4105CA0	peroxidase
HPS43_02385	ENOG4105EJC	lysr family transcriptional regulator
HPS43_02390	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HPS43_02400	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
HPS43_02415	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
HPS43_02420	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
HPS43_02425	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HPS43_02430	ENOG4105BZS	acriflavin resistance protein
HPS43_02435	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HPS43_02455	ENOG4105F4R	Transcriptional regulator mode
HPS43_02460	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HPS43_02465	ENOG4105E0C	molybdate abc transporter
HPS43_02470	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
HPS43_02475	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
HPS43_02510	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
HPS43_02520	ENOG4105C7J	ABC transporter, permease
HPS43_02530	ENOG4105CPC	Aldo Keto reductase
HPS43_02540	ENOG4105CEY	Amp-dependent synthetase and ligase
HPS43_02545	ENOG4105E39	Enoyl-CoA hydratase
HPS43_02555	ENOG4105DRR	Transcriptional regulator, GntR family
HPS43_02565	ENOG4105CHU	acetyl-coa acetyltransferase
HPS43_02570	ENOG4105D2B	acyl-CoA dehydrogenase
HPS43_02575	ENOG4105D2B	acyl-CoA dehydrogenase
HPS43_02580	ENOG4105DUM	transcriptional regulator, lysR family
HPS43_02600	ENOG4105TW1	Carbohydrate-selective porin OprB
HPS43_02605	ENOG4105DFW	ABC transporter
HPS43_02615	ENOG4108HWW	ABC transporter
HPS43_02620	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
HPS43_02625	ENOG4105E9Z	Nad-dependent epimerase dehydratase
HPS43_02630	ENOG4105ETE	Transcriptional regulator (LacI family
HPS43_02640	ENOG4108IJ7	Glycine betaine
HPS43_02645	ENOG4108HQS	Glycine betaine
HPS43_02655	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HPS43_02660	ENOG4105C2C	drug resistance transporter, Bcr CflA
HPS43_02665	ENOG4105KDC	50s ribosomal protein l28
HPS43_02670	ENOG4105W0E	50S ribosomal protein L33
HPS43_02685	ENOG4105C0Z	ABC transporter
HPS43_02705	ENOG4105DZ1	carboxypeptidase
HPS43_02715	ENOG4108VHT	MarR family transcriptional regulator
HPS43_02725	ENOG4105C8T	Leucyl-tRNA synthetase
HPS43_02740	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
HPS43_02770	ENOG4105C57	major facilitator superfamily
HPS43_02780	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
HPS43_02805	ENOG4105MP9	class II Aldolase
HPS43_02845	ENOG4105ETT	transcriptional Regulator, LysR family
HPS43_02850	ENOG4105CYC	Transferase
HPS43_02855	ENOG4105CMU	LysR family (Transcriptional regulator
HPS43_02860	ENOG4105EGS	Mechanosensitive ion channel
HPS43_02890	ENOG4107SDU	Methyl-accepting chemotaxis
HPS43_02910	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HPS43_02915	ENOG4105F38	ABC transporter, permease
HPS43_02920	ENOG4105D38	putrescine abc transporter
HPS43_02925	ENOG4105CTU	Proline racemase
HPS43_02940	ENOG41080XP	Cbs domain
HPS43_02960	ENOG4107QIJ	Aconitate hydratase 2
HPS43_02970	ENOG4105FQ6	thiopurine methyltransferase
HPS43_03000	ENOG4105CPC	Aldo Keto reductase
HPS43_03005	ENOG4105CF7	AraC family transcriptional regulator
HPS43_03010	ENOG4105HEI	LysR family (Transcriptional regulator
HPS43_03015	ENOG4105CHJ	isochorismatase hydrolase
HPS43_03025	ENOG4105Z2P	Protein of unknown function (DUF465)
HPS43_03040	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
HPS43_03045	ENOG4105CPK	Glycosyl transferase (Group 1
HPS43_03115	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HPS43_03140	ENOG4105D2S	major facilitator superfamily
HPS43_03145	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HPS43_03150	ENOG4105E2Z	phosphate ABC transporter (Permease
HPS43_03155	ENOG4105C8U	phosphate abc transporter
HPS43_03160	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
HPS43_03170	ENOG4105C9X	ppx gppa phosphatase
HPS43_03180	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
HPS43_03190	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HPS43_03195	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
HPS43_03200	ENOG4105HBR	Rna-binding protein
HPS43_03205	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HPS43_03210	ENOG4105C8Q	Methyl-accepting chemotaxis
HPS43_03215	ENOG4105C2W	permease
HPS43_03225	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
HPS43_03235	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HPS43_03250	ENOG4105EMU	Dehydrogenase
HPS43_03260	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HPS43_03265	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
HPS43_03280	ENOG4105BZU	Histidine kinase
HPS43_03285	ENOG4105ETX	regulatoR
HPS43_03300	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
HPS43_03310	ENOG4105D2X	ABC transporter substrate-binding protein
HPS43_03315	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HPS43_03330	ENOG4107QMP	dna polymerase iii subunits gamma and tau
HPS43_03340	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
HPS43_03360	ENOG4105EA8	2-Nitropropane dioxygenase
HPS43_03380	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HPS43_03395	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
HPS43_03400	ENOG4105CEY	Amp-dependent synthetase and ligase
HPS43_03415	ENOG41061WM	D-Alanyl-D-Alanine
HPS43_03430	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
HPS43_03435	ENOG4108Z66	YbaK ebsC protein
HPS43_03440	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HPS43_03445	ENOG4105ETT	transcriptional Regulator, LysR family
HPS43_03450	ENOG4105C7K	acetolactate synthase
HPS43_03455	ENOG4105C1G	acyl-Coa dehydrogenase
HPS43_03495	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HPS43_03520	ENOG4105C32	Amino acid ABC transporter (Permease)
HPS43_03530	ENOG4105C0Z	ABC transporter
HPS43_03535	ENOG4108IV0	ABC, transporter
HPS43_03545	ENOG4107QXX	ABC transporter
HPS43_03560	ENOG4107QNJ	CoA-transferase subunit B
HPS43_03565	ENOG4107HP6	Transcriptional regulator
HPS43_03570	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HPS43_03575	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HPS43_03580	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HPS43_03585	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
HPS43_03595	ENOG4105C8V	SAICAR synthetase
HPS43_03615	ENOG4105CK2	sodium dicarboxylate symporter
HPS43_03625	ENOG4105FD8	phosphonate metabolism protein PhnM
HPS43_03630	ENOG4105HRV	phosphonate c-p lyase system protein phnl
HPS43_03635	ENOG4105ENV	phosphonate C-P lyase system protein PhnK
HPS43_03640	ENOG4105FT8	Phosphonate metabolism
HPS43_03650	ENOG4105KZ6	phosphonate C-P lyase system protein PhnH
HPS43_03655	ENOG4105KQZ	Phosphonate C-P lyase system protein PhnG
HPS43_03660	ENOG4107RJJ	Transcriptional regulator
HPS43_03665	ENOG4105FD8	phosphonate metabolism protein PhnM
HPS43_03670	ENOG4105MFQ	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity)
HPS43_03675	ENOG4105MFQ	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity)
HPS43_03680	ENOG410811B	TRANSCRIPTIONal
HPS43_03685	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HPS43_03705	ENOG4105EHI	Phosphonate ABC transporter, periplasmic
HPS43_03710	ENOG4105D5T	phosphonate abc transporter
HPS43_03720	ENOG4105MHT	Transcriptional regulator, ARSR family
HPS43_03730	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
HPS43_03740	ENOG4105DR5	peptidase
HPS43_03750	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
HPS43_03760	ENOG4105CJ3	phosphate transporter
HPS43_03785	ENOG4105M4B	Catalyzes the transfer of an acetyl group from acetyl- CoA to the 6'-amino group of aminoglycoside molecules conferring resistance to antibiotics containing the purpurosamine ring (By similarity)
HPS43_03795	ENOG4108SHQ	Glutathione S-transferase
HPS43_03815	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HPS43_03820	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
HPS43_03835	ENOG4105BZA	Phosphoglycerate kinase
HPS43_03840	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HPS43_03845	ENOG4105CV1	Transketolase (EC 2.2.1.1)
HPS43_03855	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
HPS43_03870	ENOG4105C6K	Malic enzyme
HPS43_03905	ENOG4107VGR	Catalase
HPS43_03915	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
HPS43_03920	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
HPS43_03935	ENOG4105TNS	Conserved Protein
HPS43_03945	ENOG4105D7T	ABC transporter
HPS43_03955	ENOG4105I5W	Transporter
HPS43_03960	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HPS43_03965	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
HPS43_03970	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
HPS43_03995	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
HPS43_04000	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
HPS43_04015	ENOG4105VIE	preprotein translocase, subunit YajC
HPS43_04020	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HPS43_04025	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HPS43_04045	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HPS43_04055	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HPS43_04060	ENOG4105C9A	Phoh family
HPS43_04065	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
HPS43_04070	ENOG4108JU5	Magnesium and cobalt efflux protein
HPS43_04075	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
HPS43_04080	ENOG4107SET	aldo keto reductase
HPS43_04115	ENOG4108UAJ	Transcriptional regulator
HPS43_04125	ENOG4108TZV	Membrane
HPS43_04145	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
HPS43_04155	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HPS43_04165	ENOG4108ZAF	Molybdopterin
HPS43_04170	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
HPS43_04175	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HPS43_04185	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HPS43_04200	ENOG4107QIZ	NADH dehydrogenase
HPS43_04205	ENOG4108IEG	Formate dehydrogenase Alpha subunit
HPS43_04210	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
HPS43_04245	ENOG4106NZI	LysR family Transcriptional regulator
HPS43_04250	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HPS43_04255	ENOG41068KF	Universal stress protein
HPS43_04270	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HPS43_04285	ENOG4105E3J	oxidoreductase
HPS43_04300	ENOG4105CHR	reductase
HPS43_04320	ENOG4105C7F	AcnD-accessory protein PrpF
HPS43_04325	ENOG4105F04	LysR family Transcriptional regulator
HPS43_04330	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
HPS43_04365	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
HPS43_04370	ENOG4105C32	Amino acid ABC transporter (Permease)
HPS43_04380	ENOG4105C0Z	ABC transporter
HPS43_04385	ENOG4108IV0	ABC, transporter
HPS43_04395	ENOG4105E0K	tonB-dependent siderophore receptor
HPS43_04415	ENOG4108XG2	Histidine kinase
HPS43_04420	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
HPS43_04425	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HPS43_04435	ENOG4108VPT	UPF0234 protein
HPS43_04440	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
HPS43_04445	ENOG4105EHG	Permease protein
HPS43_04450	ENOG4107R4I	Periplasmic binding protein
HPS43_04455	ENOG4106QJH	hemin transport protein
HPS43_04465	ENOG4108S3W	Anti-feci sigma factor, fecr
HPS43_04470	ENOG4108SF5	RNA Polymerase
HPS43_04485	ENOG4105D29	Helix-turn-helix type 11 domain protein
HPS43_04510	ENOG4105CBN	LysR family transcriptional regulator
HPS43_04515	ENOG4105C85	amino acid
HPS43_04525	ENOG4105F7P	transcriptional regulator AsnC family
HPS43_04530	ENOG4108UT2	hemolysin iii
HPS43_04535	ENOG4105KXX	peptidase s58 dmpa
HPS43_04540	ENOG4105EAB	amino acid AbC transporter
HPS43_04545	ENOG4105E5Q	amino acid AbC transporter
HPS43_04550	ENOG4105CDA	abc transporter atp-binding protein
HPS43_04555	ENOG4108K5P	(LipO)protein
HPS43_04590	ENOG4105TX3	Histidine kinase
HPS43_04595	ENOG4108UYB	regulatoR
HPS43_04600	ENOG4105E2S	oxidase) subunit II
HPS43_04605	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HPS43_04610	ENOG4105CCU	oxidase (Subunit III)
HPS43_04615	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
HPS43_04625	ENOG4105CHB	tonB-dependent Receptor
HPS43_04645	ENOG4105C6K	Malic enzyme
HPS43_04660	ENOG4108PCN	EamA-like transporter family
HPS43_04680	ENOG4105DUM	transcriptional regulator, lysR family
HPS43_04695	ENOG4105CHR	reductase
HPS43_04705	ENOG4107NQ8	LysR family Transcriptional regulator
HPS43_04725	ENOG4108JCI	Transcriptional regulator
HPS43_04730	ENOG4107RZC	phospholipase d
HPS43_04740	ENOG4105CF1	Alkylated DNA repair protein
HPS43_04755	ENOG4105E6M	Sulphatase-modifying factor protein
HPS43_04770	ENOG4105F1J	Homogentisate 1,2-dioxygenase
HPS43_04775	ENOG4108302	MgtC SapB transporter
HPS43_04780	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HPS43_04785	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
HPS43_04800	ENOG4107QM5	aconitate hydratase
HPS43_04815	ENOG4108S3W	Anti-feci sigma factor, fecr
HPS43_04820	ENOG4108SF5	RNA Polymerase
HPS43_04825	ENOG4108MP6	LysR family Transcriptional regulator
HPS43_04830	ENOG4107GJV	short-chain dehydrogenase reductase
HPS43_04835	ENOG4105CNM	Receptor
HPS43_04855	ENOG4105CK1	PTS System
HPS43_04860	ENOG4105EPW	hflc protein
HPS43_04875	ENOG4105D4Y	metalloprotease
HPS43_04885	ENOG4105DJ2	Major Facilitator Superfamily
HPS43_04890	ENOG4105R1U	AraC Family Transcriptional Regulator
HPS43_04895	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
HPS43_04905	ENOG4105DU1	integral membrane protein, terc
HPS43_04910	ENOG41063Z6	transcriptional regulator, lysR family
HPS43_04940	ENOG41067B5	Histone deacetylase superfamily protein
HPS43_04960	ENOG4105CSH	Transporter
HPS43_04965	ENOG4105E2S	oxidase) subunit II
HPS43_04970	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HPS43_04975	ENOG4105CCU	oxidase (Subunit III)
HPS43_04980	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
HPS43_04990	ENOG4108Z9W	Outer membrane porin
HPS43_04995	ENOG4108Z9W	Outer membrane porin
HPS43_05000	ENOG4108Z9W	Outer membrane porin
HPS43_05010	ENOG4105E5M	Multidrug resistance protein D
HPS43_05065	ENOG4105HSS	phospholipase C
HPS43_05090	ENOG4107QZF	nitrite reductase NADPH large subunit
HPS43_05095	ENOG4107QZF	nitrite reductase NADPH large subunit
HPS43_05100	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
HPS43_05110	ENOG4105CPC	Aldo Keto reductase
HPS43_05125	ENOG4105CV8	reductase
HPS43_05130	ENOG4105HEI	LysR family (Transcriptional regulator
HPS43_05150	ENOG4105EJC	lysr family transcriptional regulator
HPS43_05155	ENOG4105CMJ	mandelate racemase muconate lactonizing
HPS43_05170	ENOG4105C8Q	Methyl-accepting chemotaxis
HPS43_05175	ENOG410620I	Diguanylate cyclase
HPS43_05180	ENOG4105MHT	Transcriptional regulator, ARSR family
HPS43_05190	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HPS43_05195	ENOG4105C6X	Major Facilitator
HPS43_05225	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HPS43_05235	ENOG4108WC5	Alpha Beta Hydrolase Fold protein
HPS43_05240	ENOG4105K5X	acetyltransferase
HPS43_05245	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
HPS43_05260	ENOG4108M0I	Transcriptional regulator
HPS43_05270	ENOG4105MP9	class II Aldolase
HPS43_05315	ENOG4105PGM	cation diffusion facilitator family transporter
HPS43_05335	ENOG4105BZ1	(ABC) transporter
HPS43_05345	ENOG4107QRT	dEAD DEAH box helicase
HPS43_05350	ENOG4107T0X	DNA ligase
HPS43_05355	ENOG4107T0X	DNA ligase
HPS43_05385	ENOG4108KHN	disulfide isomerase, thiol-disulfide oxidase
HPS43_05390	ENOG4105C1G	acyl-Coa dehydrogenase
HPS43_05400	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HPS43_05405	ENOG4108PCN	EamA-like transporter family
HPS43_05410	ENOG4105CWC	Acetylornithine deacetylase
HPS43_05430	ENOG4105C5Q	Transcriptional regulator
HPS43_05435	ENOG410642W	LysR family Transcriptional regulator
HPS43_05465	ENOG4105F52	Transcriptional regulator
HPS43_05470	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HPS43_05480	ENOG4105CMJ	mandelate racemase muconate lactonizing
HPS43_05490	ENOG4108Z9W	Outer membrane porin
HPS43_05495	ENOG4105CEY	Amp-dependent synthetase and ligase
HPS43_05540	ENOG4108SF5	RNA Polymerase
HPS43_05570	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
HPS43_05575	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
HPS43_05585	ENOG4108U05	Transcriptional regulator
HPS43_05600	ENOG4105DUM	transcriptional regulator, lysR family
HPS43_05630	ENOG4108IUZ	ABC transporter
HPS43_05635	ENOG4108IV0	ABC, transporter
HPS43_05640	ENOG4105DEI	Mannitol dehydrogenase
HPS43_05645	ENOG41080IJ	Diacylglycerol kinase
HPS43_05650	ENOG4105CEP	NADH dehydrogenase
HPS43_05655	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
HPS43_05660	ENOG4107TH8	cina domain protein
HPS43_05670	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
HPS43_05675	ENOG4107YIM	Involved in the transcription termination process (By similarity)
HPS43_05680	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
HPS43_05685	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HPS43_05705	ENOG4105D5T	phosphonate abc transporter
HPS43_05735	ENOG4106H78	methyltransferase
HPS43_05740	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
HPS43_05745	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
HPS43_05750	ENOG4105DKK	Benzoate
HPS43_05785	ENOG4105CNM	Receptor
HPS43_05805	ENOG4105D8D	Type III
HPS43_05820	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HPS43_05840	ENOG4105DFP	Integrase
HPS43_05845	ENOG4105C3G	gtp-binding protein
HPS43_05855	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
HPS43_05875	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
HPS43_05880	ENOG4105C8Q	Methyl-accepting chemotaxis
HPS43_05890	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
HPS43_05895	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
HPS43_05920	ENOG4105F1J	Homogentisate 1,2-dioxygenase
HPS43_05930	ENOG4106HNH	Acyl-transferase
HPS43_05935	ENOG4105E0M	Sulfatase
HPS43_05940	ENOG4107YCY	Transcriptional regulator
HPS43_05945	ENOG4105E9Z	Nad-dependent epimerase dehydratase
HPS43_05955	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HPS43_05965	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HPS43_05975	ENOG4105BZU	Histidine kinase
HPS43_05980	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HPS43_05985	ENOG4105CQB	FAD linked oxidase domain protein
HPS43_06000	ENOG4107QP8	phosphohexose isomerase
HPS43_06005	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HPS43_06010	ENOG4105CGN	Glycosyl transferase (Group 1
HPS43_06015	ENOG4108KMV	Glycosyl transferase (Group 1
HPS43_06020	ENOG4107STW	synthase
HPS43_06030	ENOG4105CG5	Glycosyl transferase (Group 1
HPS43_06045	ENOG4107QQG	Dehydrogenase
HPS43_06050	ENOG4107UKG	Glycosyl transferase, family 4
HPS43_06070	ENOG4105BZU	Histidine kinase
HPS43_06080	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HPS43_06085	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HPS43_06090	ENOG4105C26	Dehydrogenase
HPS43_06115	ENOG4108JQ6	ABC transporter
HPS43_06120	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HPS43_06135	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HPS43_06140	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
HPS43_06145	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HPS43_06155	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HPS43_06160	ENOG4105CBX	hi0933 family
HPS43_06165	ENOG4105CXN	decarboxylase
HPS43_06180	ENOG4105BZU	Histidine kinase
HPS43_06190	ENOG4105DHP	deoxycytidine triphosphate deaminase
HPS43_06215	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HPS43_06220	ENOG4105C72	UPF0176 protein
HPS43_06235	ENOG4105EXC	Acyl-transferase
HPS43_06245	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HPS43_06250	ENOG4107SVH	Potassium channel protein
HPS43_06255	ENOG4108ZVF	(LipO)protein
HPS43_06275	ENOG4105CXC	rtn protein
HPS43_06285	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
HPS43_06290	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HPS43_06295	ENOG4105D0S	secretion protein (HlyD
HPS43_06300	ENOG4105CJ1	ABC, transporter
HPS43_06305	ENOG4105CMI	transporter
HPS43_06315	ENOG4105CHR	reductase
HPS43_06320	ENOG4105CC0	LysR family Transcriptional regulator
HPS43_06325	ENOG4108KTG	Membrane protein, drug metabolite transporter
HPS43_06335	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HPS43_06340	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HPS43_06350	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HPS43_06370	ENOG41079YP	Citrate utilization protein b
HPS43_06385	ENOG4105NQN	cytochrome C
HPS43_06395	ENOG4105CYM	Glutathione S-transferase
HPS43_06400	ENOG4105C84	Histidine ammonia-lyase
HPS43_06405	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
HPS43_06410	ENOG4105CSH	Transporter
HPS43_06415	ENOG4105CGP	Urocanate hydratase
HPS43_06430	ENOG4105CD3	dihydroorotase
HPS43_06455	ENOG4105YK5	50S ribosomal protein L36
HPS43_06465	ENOG4108I0Z	Aconitate hydratase
HPS43_06470	ENOG4105C7F	AcnD-accessory protein PrpF
HPS43_06475	ENOG4108SF5	RNA Polymerase
HPS43_06480	ENOG4108S3W	Anti-feci sigma factor, fecr
HPS43_06485	ENOG4105CNM	Receptor
HPS43_06490	ENOG4105CH7	arginosuccinase
HPS43_06495	ENOG4105JJR	Histidine kinase
HPS43_06505	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
HPS43_06535	ENOG4105CSH	Transporter
HPS43_06545	ENOG4105CHR	reductase
HPS43_06550	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
HPS43_06565	ENOG4105EVD	ribosomal RNA large subunit methyltransferase N
HPS43_06570	ENOG4105JSC	dimethylmenaquinone methyltransferase
HPS43_06575	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HPS43_06580	ENOG4105BZN	citrate synthase
HPS43_06585	ENOG4105CXK	mandelate racemase muconate lactonizing
HPS43_06620	ENOG4106NZI	LysR family Transcriptional regulator
HPS43_06625	ENOG4105C0H	protease
HPS43_06630	ENOG4105D0M	Protease HtpX homolog
HPS43_06675	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HPS43_06685	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HPS43_06690	ENOG4105VN1	Heat shock protein
HPS43_06700	ENOG4105EQR	Transposase IS116 IS110 IS902
HPS43_06710	ENOG4106NZI	LysR family Transcriptional regulator
HPS43_06725	ENOG4107QJE	Chromosome Partitioning Protein
HPS43_06765	ENOG4108IYH	Dna topoisomerase
HPS43_06900	ENOG4108ZXE	
HPS43_06965	ENOG4105W5Q	DNA repair protein (RadC
HPS43_07000	ENOG4108R8Z	these effects are overcome by concomitant expression of antitoxin SohA (PrlF). Massive overexpression is toxic. Unlike most other characterized TA systems degrades rRNA, and co-folding of the proteins is necessary in vitro for inhibition of the RNase activity. It is not known if it has any sequence-specificity. Acts as a transcription factor. The YhaV PrlF complex binds the prlF-yhaV operon, probably negatively regulating its expression
HPS43_07025	ENOG4105DFP	Integrase
HPS43_07040	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
HPS43_07045	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HPS43_07055	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
HPS43_07065	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
HPS43_07075	ENOG4109066	lysm domain bon superfamily protein
HPS43_07080	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HPS43_07085	ENOG4105CRE	cytochrome C
HPS43_07100	ENOG4108TGY	Glutathione S-transferase
HPS43_07135	ENOG4105C26	Dehydrogenase
HPS43_07145	ENOG4105DFG	type I secretion outer membrane protein
HPS43_07150	ENOG4107QZV	Type I secretion membrane fusion protein
HPS43_07155	ENOG4108JJ6	Type I secretion system ATPase
HPS43_07170	ENOG4105CAF	HipA N-terminal domain protein
HPS43_07190	ENOG4107HP6	Transcriptional regulator
HPS43_07200	ENOG4108RTU	Aldolase
HPS43_07205	ENOG4105CXK	mandelate racemase muconate lactonizing
HPS43_07210	ENOG4105DJB	Major Facilitator Superfamily
HPS43_07215	ENOG4105CJ1	ABC, transporter
HPS43_07235	ENOG4105F27	Major Facilitator
HPS43_07240	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
HPS43_07250	ENOG4105C2W	permease
HPS43_07335	ENOG4107QXX	ABC transporter
HPS43_07340	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
HPS43_07355	ENOG4105CHR	reductase
HPS43_07470	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HPS43_07475	ENOG4105I6B	RNA polymerase
HPS43_07495	ENOG4106NZI	LysR family Transcriptional regulator
HPS43_07505	ENOG4105NTW	Transcriptional regulator
HPS43_07525	ENOG4105II7	pyrroline-5-carboxylate reductase
HPS43_07535	ENOG4105CQB	FAD linked oxidase domain protein
HPS43_07545	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HPS43_07550	ENOG4105F38	ABC transporter, permease
HPS43_07555	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HPS43_07570	ENOG4105IPI	Membrane
HPS43_07575	ENOG4105CBN	LysR family transcriptional regulator
HPS43_07580	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
HPS43_07590	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HPS43_07600	ENOG4105GP2	5'(3')-deoxyribonucleotidase
HPS43_07610	ENOG4107YCY	Transcriptional regulator
HPS43_07620	ENOG4105E2X	shikimate dehydrogenase
HPS43_07630	ENOG4105C32	Amino acid ABC transporter (Permease)
HPS43_07640	ENOG4105C0Z	ABC transporter
HPS43_07645	ENOG4108IV0	ABC, transporter
HPS43_07655	ENOG4108JYK	Dehydrogenase
HPS43_07670	ENOG4107QN2	dihydrolipoyl dehydrogenase
HPS43_07675	ENOG4105HEI	LysR family (Transcriptional regulator
HPS43_07680	ENOG4105C01	Dihydroxy-acid dehydratase
HPS43_07690	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HPS43_07695	ENOG4105DUM	transcriptional regulator, lysR family
HPS43_07710	ENOG4105CXC	rtn protein
HPS43_07715	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
HPS43_07720	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
HPS43_07725	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HPS43_07730	ENOG4105CRW	Short chain fatty acid transporter
HPS43_07740	ENOG4107HP6	Transcriptional regulator
HPS43_07750	ENOG4107QNJ	CoA-transferase subunit B
HPS43_07765	ENOG4105F2Z	3-oxoadipate enol-lactonase
HPS43_07790	ENOG4108PVQ	transcriptional regulator
HPS43_07795	ENOG4105CHR	reductase
HPS43_07805	ENOG4105C32	Amino acid ABC transporter (Permease)
HPS43_07810	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
HPS43_07815	ENOG4105C0Z	ABC transporter
HPS43_07820	ENOG4108IV0	ABC, transporter
HPS43_07825	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
HPS43_07830	ENOG4105CHR	reductase
HPS43_07835	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
HPS43_07840	ENOG4108U78	Glutathione S-transferase
HPS43_07865	ENOG4107NQ8	LysR family Transcriptional regulator
HPS43_07870	ENOG4105C57	major facilitator superfamily
HPS43_07895	ENOG4105CEY	Amp-dependent synthetase and ligase
HPS43_07915	ENOG4105D01	(LipO)protein
HPS43_07925	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HPS43_07935	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HPS43_07940	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
HPS43_07955	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HPS43_07960	ENOG410829K	Lysine exporter protein (Lyse ygga)
HPS43_07985	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
HPS43_07990	ENOG4105UGU	tonB-dependent Receptor
HPS43_08000	ENOG4105CSH	Transporter
HPS43_08005	ENOG4105DDW	LysR family Transcriptional regulator
HPS43_08010	ENOG4107YCY	Transcriptional regulator
HPS43_08015	ENOG4105G63	Type III effector Hrp-dependent
HPS43_08020	ENOG4105ZXK	Dehydrogenase
HPS43_08025	ENOG4105EXW	epimerase dehydratase
HPS43_08030	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
HPS43_08035	ENOG4105FB2	class II Aldolase
HPS43_08105	ENOG4105EAH	synthase
HPS43_08110	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
HPS43_08115	ENOG4105K46	50S ribosomal protein l27
HPS43_08120	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HPS43_08125	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
HPS43_08140	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HPS43_08145	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
HPS43_08155	ENOG4108QBF	Transcriptional regulator
HPS43_08160	ENOG4105BZU	Histidine kinase
HPS43_08165	ENOG4105D06	uba thif-type nad fad binding protein
HPS43_08170	ENOG4105CN1	protease
HPS43_08175	ENOG41063SB	peptidase
HPS43_08180	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HPS43_08185	ENOG4105C72	UPF0176 protein
HPS43_08190	ENOG4105VW4	glutaredoxin 3
HPS43_08195	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
HPS43_08200	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
HPS43_08215	ENOG4105MJ2	Competence protein
HPS43_08220	ENOG4106T9E	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HPS43_08225	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
HPS43_08230	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
HPS43_08235	ENOG4105C1A	potassium transporter peripheral membrane
HPS43_08240	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HPS43_08245	ENOG4105ES5	Histidine kinase
HPS43_08255	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HPS43_08260	ENOG410829K	Lysine exporter protein (Lyse ygga)
HPS43_08265	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
HPS43_08275	ENOG4105KVH	Transcriptional regulator
HPS43_08285	ENOG4108URH	decarboxylase
HPS43_08295	ENOG4108YZS	Had-superfamily hydrolase, subfamily ia, variant 1
HPS43_08305	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
HPS43_08310	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HPS43_08315	ENOG4105C79	DNA protecting protein DprA
HPS43_08320	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
HPS43_08330	ENOG4107QXX	ABC transporter
HPS43_08335	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HPS43_08340	ENOG4105DFA	alanine racemase domain protein
HPS43_08360	ENOG4105W39	Membrane
HPS43_08365	ENOG4105C7B	Threonine dehydratase
HPS43_08370	ENOG4108Z9W	Outer membrane porin
HPS43_08385	ENOG4105EXG	Transcriptional regulator
HPS43_08390	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
HPS43_08395	ENOG4108JJ8	(ABC) transporter
HPS43_08400	ENOG4108JJ9	ABC, transporter
HPS43_08410	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HPS43_08415	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HPS43_08425	ENOG4108EF9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
HPS43_08430	ENOG4105C2X	Arabinose 5-phosphate isomerase
HPS43_08435	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
HPS43_08450	ENOG4108IUZ	ABC transporter
HPS43_08455	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
HPS43_08460	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
HPS43_08465	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
HPS43_08470	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HPS43_08485	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
HPS43_08495	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HPS43_08500	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HPS43_08505	ENOG41082RQ	UPF0102 protein
HPS43_08510	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
HPS43_08515	ENOG4105W4M	Transport-associated protein
HPS43_08520	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HPS43_08525	ENOG4105D01	(LipO)protein
HPS43_08530	ENOG4105CAS	nag kinase
HPS43_08540	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
HPS43_08545	ENOG4107QPK	)-transporter
HPS43_08550	ENOG4105DG4	malate L-lactate dehydrogenase
HPS43_08555	ENOG4105CNI	cell division protein FtsW
HPS43_08560	ENOG4105CJN	penicillin-binding protein
HPS43_08570	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
HPS43_08580	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HPS43_08585	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HPS43_08590	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HPS43_08605	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
HPS43_08610	ENOG4105CGK	Exodeoxyribonuclease III
HPS43_08615	ENOG4105D82	Glutamate dehydrogenase
HPS43_08625	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
HPS43_08635	ENOG410810E	transcriptional regulator, lysR family
HPS43_08640	ENOG4105CP9	extracellular ligand-binding receptor
HPS43_08650	ENOG4105C0Z	ABC transporter
HPS43_08655	ENOG4108IV0	ABC, transporter
HPS43_08660	ENOG4108ZHJ	Organic hydroperoxide resistance protein
HPS43_08665	ENOG4105K56	Transcriptional regulator
HPS43_08680	ENOG4105C0Z	ABC transporter
HPS43_08685	ENOG4105C32	Amino acid ABC transporter (Permease)
HPS43_08700	ENOG4108IV0	ABC, transporter
HPS43_08705	ENOG4105DZS	Phenylacetate-CoA ligase
HPS43_08725	ENOG41080HT	Transcriptional regulator, arsr family
HPS43_08735	ENOG4105CSR	polyphosphate kinase 2
HPS43_08755	ENOG4105K78	MarR family Transcriptional regulator
HPS43_08770	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
HPS43_08780	ENOG4105DWF	phosphomethylpyrimidine kinase
HPS43_08840	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
HPS43_08845	ENOG4105C1J	atp-dependent rna helicase
HPS43_08855	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HPS43_08860	ENOG4107SC1	transglycosylase
HPS43_08865	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
HPS43_08895	ENOG4105SYT	Methylenetetrahydrofolate reductase
HPS43_08900	ENOG41086DT	Membrane protein of unknown function
HPS43_08905	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
HPS43_08910	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HPS43_08925	ENOG4108TFY	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HPS43_08940	ENOG4105EJC	lysr family transcriptional regulator
HPS43_08950	ENOG4105CSH	Transporter
HPS43_08955	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HPS43_08960	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HPS43_08975	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
HPS43_08985	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HPS43_08990	ENOG4105D7X	high-affinity nickel-transporter
HPS43_09000	ENOG4105DSE	periplasmic solute binding protein
HPS43_09005	ENOG4105CC5	ABC transporter
HPS43_09010	ENOG4105DIK	(ABC) transporter
HPS43_09015	ENOG4105MYN	Zinc uptake regulation protein
HPS43_09020	ENOG4105CKI	cobalamin synthesis protein
HPS43_09030	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
HPS43_09035	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
HPS43_09045	ENOG4108WBT	adenosyltransferase
HPS43_09055	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HPS43_09065	ENOG4105CKK	Glycosyl transferase, family 2
HPS43_09080	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HPS43_09100	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
HPS43_09115	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
HPS43_09120	ENOG4108Z43	UPF0250 protein
HPS43_09130	ENOG4105DZ1	carboxypeptidase
HPS43_09155	ENOG4105CY3	ABC transporter, permease
HPS43_09165	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
HPS43_09180	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
HPS43_09185	ENOG4105D16	lipopolysaccharide heptosyltransferase i
HPS43_09195	ENOG4105ESV	Glycosyl transferase, family 4
HPS43_09215	ENOG4105EQK	-acetyltransferase
HPS43_09235	ENOG4105D2T	synthase
HPS43_09245	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
HPS43_09250	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
HPS43_09255	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
HPS43_09275	ENOG4105C5E	polysaccharide biosynthesis protein
HPS43_09280	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HPS43_09285	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HPS43_09295	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HPS43_09305	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
HPS43_09310	ENOG4105DZQ	phospholipase D Transphosphatidylase
HPS43_09315	ENOG4105X23	Endonuclease Exonuclease phosphatase
HPS43_09320	ENOG4105C9M	aspartyl-trna synthetase
HPS43_09345	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HPS43_09360	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HPS43_09365	ENOG4108ZGC	gaf domain protein
HPS43_09370	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HPS43_09395	ENOG4108KWP	DNA-binding transcriptional regulator GlcC
HPS43_09430	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
HPS43_09440	ENOG4107RDB	Major Facilitator
HPS43_09445	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HPS43_09450	ENOG4108RXX	maleylacetoacetate isomerase
HPS43_09455	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
HPS43_09460	ENOG4105D49	3-dehydroquinate synthase
HPS43_09465	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HPS43_09470	ENOG4108JQC	penicillin-binding protein 1A
HPS43_09475	ENOG4105XQ6	frataxin-like protein
HPS43_09485	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
HPS43_09495	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
HPS43_09505	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
HPS43_09510	ENOG4105D52	delta-aminolevulinic acid dehydratase
HPS43_09520	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
HPS43_09525	ENOG4105VF7	tolerance protein
HPS43_09535	ENOG4108ZT0	50S ribosomal protein l17
HPS43_09540	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HPS43_09545	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
HPS43_09550	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
HPS43_09555	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HPS43_09565	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
HPS43_09570	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HPS43_09575	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
HPS43_09580	ENOG4105VPB	50S ribosomal protein L30
HPS43_09585	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
HPS43_09590	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
HPS43_09595	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
HPS43_09600	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
HPS43_09605	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HPS43_09610	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HPS43_09615	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
HPS43_09620	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
HPS43_09635	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HPS43_09660	ENOG4105C0Z	ABC transporter
HPS43_09665	ENOG4108IV0	ABC, transporter
HPS43_09685	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
HPS43_09690	ENOG41084PQ	50s ribosomal protein l29
HPS43_09695	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
HPS43_09700	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
HPS43_09705	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
HPS43_09710	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
HPS43_09715	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HPS43_09720	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
HPS43_09730	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
HPS43_09735	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
HPS43_09740	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HPS43_09745	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HPS43_09750	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
HPS43_09755	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
HPS43_09760	ENOG4107EXC	regulatoR
HPS43_09775	ENOG4105BZU	Histidine kinase
HPS43_09790	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HPS43_09795	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HPS43_09800	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
HPS43_09805	ENOG4108VZM	50s ribosomal protein L10
HPS43_09810	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
HPS43_09815	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
HPS43_09825	ENOG410683Z	Preprotein translocase SecE subunit
HPS43_09835	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HPS43_09875	ENOG4107QKW	extracellular solute-binding protein family 1
HPS43_09880	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HPS43_09915	ENOG4107NQ8	LysR family Transcriptional regulator
HPS43_09920	ENOG4105HDK	L-asparaginase
HPS43_09925	ENOG4105FA0	parb-like partition protein
HPS43_09935	ENOG4107QJE	Chromosome Partitioning Protein
HPS43_09940	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
HPS43_09945	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
HPS43_09950	ENOG4105VEQ	Cold shock protein
HPS43_09955	ENOG4108KK1	membrane protein AbrB duplication
HPS43_09960	ENOG4105CHM	Aminotransferase
HPS43_10000	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
HPS43_10015	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HPS43_10020	ENOG4105C3U	ABC transporter
HPS43_10025	ENOG4108JQ7	(ABC) transporter
HPS43_10030	ENOG4105CH2	amidohydrolase
HPS43_10050	ENOG4105C6T	cysteine synthase
HPS43_10055	ENOG4105CH6	catalase
HPS43_10065	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
HPS43_10075	ENOG4105VG0	50S ribosomal protein l34
HPS43_10080	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
HPS43_10085	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HPS43_10090	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HPS43_10095	ENOG4105CC0	LysR family Transcriptional regulator
HPS43_10110	ENOG4105C2I	pirin domain protein
HPS43_10120	ENOG4105EFZ	amidohydrolase
HPS43_10135	ENOG4105RQF	LysR family Transcriptional regulator
HPS43_10140	ENOG4107RP9	extracellular solute-binding protein, family 3
HPS43_10145	ENOG4105EAD	ABC transporter
HPS43_10150	ENOG4105DRP	amino acid AbC transporter
HPS43_10155	ENOG4105CDA	abc transporter atp-binding protein
HPS43_10165	ENOG4108594	Permease of the drug metabolite transporter
HPS43_10195	ENOG4105F38	ABC transporter, permease
HPS43_10200	ENOG4105D38	putrescine abc transporter
HPS43_10225	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
HPS43_10255	ENOG4105CMD	Transcriptional regulator, GntR family
HPS43_10265	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HPS43_10270	ENOG4105F38	ABC transporter, permease
HPS43_10275	ENOG4105D38	putrescine abc transporter
HPS43_10300	ENOG4105M4H	endoribonuclease L-psp
HPS43_10305	ENOG4105DZC	cytosine deaminase
HPS43_10315	ENOG4105UIB	(ABC) transporter
HPS43_10320	ENOG4108JQ9	ABC transporter
HPS43_10325	ENOG4107TFB	basic membrane
HPS43_10335	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
HPS43_10350	ENOG4108MEJ	flavin reductase domain protein
HPS43_10365	ENOG4105F9N	Major Facilitator Superfamily
HPS43_10380	ENOG4105FFC	UPF0187 protein
HPS43_10385	ENOG4108YXU	transcriptional regulator AsnC family
HPS43_10390	ENOG4105C7K	acetolactate synthase
HPS43_10395	ENOG4105CHR	reductase
HPS43_10400	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
HPS43_10415	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HPS43_10425	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
HPS43_10430	ENOG4108RPN	Protein smg homolog
HPS43_10440	ENOG4105H1G	trap transporter solute receptor taxi family
HPS43_10460	ENOG4105E5Q	amino acid AbC transporter
HPS43_10465	ENOG4105E5Q	amino acid AbC transporter
HPS43_10470	ENOG4106TNF	Periplasmic binding protein
HPS43_10475	ENOG4105KWI	UPF0339 protein
HPS43_10485	ENOG4105C8Y	Acetylornithine aminotransferase
HPS43_10495	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HPS43_10545	ENOG4105ECQ	AraC Family Transcriptional Regulator
HPS43_10550	ENOG4105VCH	membrane
HPS43_10560	ENOG4105W2W	Cytotoxic translational repressor of toxin-antitoxin stability system
HPS43_10580	ENOG4108NIW	Leucine export protein LeuE
HPS43_10600	ENOG4105JXH	GntR family transcriptional regulator
HPS43_10605	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HPS43_10615	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
HPS43_10660	ENOG4108SF5	RNA Polymerase
HPS43_10665	ENOG4105CEY	Amp-dependent synthetase and ligase
HPS43_10680	ENOG4105CHR	reductase
HPS43_10710	ENOG4105E8G	Major facilitator Superfamily
HPS43_10725	ENOG4108WFR	AraC Family Transcriptional Regulator
HPS43_10745	ENOG4107QX3	carboxylase
HPS43_10750	ENOG4105CHU	acetyl-coa acetyltransferase
HPS43_10755	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
HPS43_10760	ENOG4105C1G	acyl-Coa dehydrogenase
HPS43_10765	ENOG4105CH2	amidohydrolase
HPS43_10775	ENOG4105KK4	UPF0060 membrane protein
HPS43_10780	ENOG4108Z6Z	Transcriptional regulator
HPS43_10790	ENOG410829K	Lysine exporter protein (Lyse ygga)
HPS43_10805	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
HPS43_10815	ENOG4108Z33	Thiol disulfide Interchange Protein
HPS43_10825	ENOG4105C75	arginyL-tRNA synthetase
HPS43_10840	ENOG4105DRS	transport system, permease
HPS43_10845	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
HPS43_10850	ENOG4105BZ7	extracellular solute-binding protein family 1
HPS43_10855	ENOG4108IJ9	(ABC) transporter
HPS43_10860	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
HPS43_10865	ENOG4105ETE	Transcriptional regulator (LacI family
HPS43_10875	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HPS43_10890	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HPS43_10910	ENOG4108UQY	Iron-storage protein
HPS43_10920	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
HPS43_10925	ENOG410829K	Lysine exporter protein (Lyse ygga)
HPS43_10930	ENOG4105C1J	atp-dependent rna helicase
HPS43_10935	ENOG4106J39	exported protein
HPS43_10940	ENOG4106J39	exported protein
HPS43_10945	ENOG4105CI2	imidazolone-5-propionate hydrolase
HPS43_10955	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HPS43_10960	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HPS43_10965	ENOG4105DEF	Extracellular solute-binding protein, family 5
HPS43_10970	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
HPS43_10975	ENOG4105KD1	integral membrane protein
HPS43_10980	ENOG4105UEI	Transcriptional Regulator AraC Family
HPS43_10990	ENOG4105C3J	Cysteine desulfurase
HPS43_11000	ENOG4105ETT	transcriptional Regulator, LysR family
HPS43_11015	ENOG4105C6Z	Gluconate
HPS43_11035	ENOG4105KB2	stringent starvation protein b
HPS43_11040	ENOG4107MKT	Stringent starvation protein a
HPS43_11045	ENOG4105EIX	cytochrome c1
HPS43_11050	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HPS43_11055	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HPS43_11060	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
HPS43_11065	ENOG4107QNR	UPF0135 protein
HPS43_11070	ENOG4105C0H	protease
HPS43_11085	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
HPS43_11090	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HPS43_11095	ENOG4107YU2	histidine triad (hIT) protein
HPS43_11100	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
HPS43_11110	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
HPS43_11115	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
HPS43_11120	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
HPS43_11125	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
HPS43_11130	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HPS43_11135	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
HPS43_11140	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
HPS43_11145	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HPS43_11155	ENOG4105E3A	(ABC) transporter
HPS43_11160	ENOG4105DA5	(ABC) transporter
HPS43_11170	ENOG410903C	(LipO)protein
HPS43_11175	ENOG4107PE3	Mammalian cell entry related domain protein
HPS43_11180	ENOG4105CY3	ABC transporter, permease
HPS43_11185	ENOG4105DHJ	ABC, transporter
HPS43_11190	ENOG4105EA8	2-Nitropropane dioxygenase
HPS43_11200	ENOG4105CBP	Major Facilitator
HPS43_11205	ENOG4105EGI	Transcriptional regulator
HPS43_11210	ENOG4105EIF	outer membrane protein W
HPS43_11215	ENOG4105DND	Transcriptional regulator
HPS43_11220	ENOG4105E7W	lamb ycsf family protein
HPS43_11225	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
HPS43_11230	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HPS43_11275	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HPS43_11280	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
HPS43_11295	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
HPS43_11300	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HPS43_11310	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
HPS43_11330	ENOG4107SGF	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
HPS43_11360	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HPS43_11365	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HPS43_11370	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HPS43_11375	ENOG4105CG5	Glycosyl transferase (Group 1
HPS43_11420	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
HPS43_11435	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
HPS43_11455	ENOG4105E0K	tonB-dependent siderophore receptor
HPS43_11460	ENOG4105PEC	Iron-enterobactin transporter periplasmic binding protein
HPS43_11465	ENOG4105DQ5	transport system permease protein
HPS43_11470	ENOG4105TVJ	transport system, permease
HPS43_11475	ENOG4105E0A	ABC, transporter
HPS43_11495	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
HPS43_11505	ENOG4106B0W	Curli production assembly transport component CsgG
HPS43_11515	ENOG4107Y60	(LipO)protein
HPS43_11520	ENOG4108IYU	L-aspartate oxidase
HPS43_11525	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
HPS43_11530	ENOG4105EQ0	Major Facilitator superfamily
HPS43_11535	ENOG4105CR8	Transcriptional regulator
HPS43_11545	ENOG4107QWB	Ornithine cyclodeaminase
HPS43_11550	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
HPS43_11555	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
HPS43_11560	ENOG4105EVZ	LysR family transcriptional regulator
HPS43_11565	ENOG4105CK7	Sodium proline symporter
HPS43_11570	ENOG4105CYW	agmatinase
HPS43_11575	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
HPS43_11630	ENOG4105CGH	5'-nucleotidase
HPS43_11645	ENOG4105CZE	histidine utilization repressor
HPS43_11650	ENOG41090B9	response to stress
HPS43_11655	ENOG4105CGP	Urocanate hydratase
HPS43_11660	ENOG4105ETS	cytosine purines uracil thiamine allantoin
HPS43_11675	ENOG4105C8Q	Methyl-accepting chemotaxis
HPS43_11680	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HPS43_11755	ENOG4105DRR	Transcriptional regulator, GntR family
HPS43_11770	ENOG4105C26	Dehydrogenase
HPS43_11795	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HPS43_11805	ENOG4105DEF	Extracellular solute-binding protein, family 5
HPS43_11815	ENOG4107T8P	acyl-Coa dehydrogenase
HPS43_11820	ENOG4107T8P	acyl-Coa dehydrogenase
HPS43_11830	ENOG4105D01	(LipO)protein
HPS43_11835	ENOG4108UZX	fmn reductase
HPS43_11840	ENOG4105GVF	(ABC) transporter
HPS43_11845	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
HPS43_11850	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
HPS43_11855	ENOG4107T8P	acyl-Coa dehydrogenase
HPS43_11865	ENOG4108UMI	ABC transporter, permease
HPS43_11870	ENOG4105D01	(LipO)protein
HPS43_11875	ENOG4105E2Y	ABC, transporter
HPS43_11880	ENOG4105X1Q	TOBE domain protein
HPS43_11885	ENOG4108NST	exported protein
HPS43_11910	ENOG4108S4H	thioesterase Superfamily protein
HPS43_11925	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
HPS43_11930	ENOG4108MG3	formate dehydrogenase
HPS43_11935	ENOG4105F46	Necessary for formate dehydrogenase activity (By similarity)
HPS43_11945	ENOG4105EM7	Selenocysteine-specific translation elongation factor
HPS43_11960	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HPS43_11965	ENOG4108KS2	transglutaminase domain protein
HPS43_11970	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
HPS43_11980	ENOG4105ETT	transcriptional Regulator, LysR family
HPS43_12005	ENOG4105C26	Dehydrogenase
HPS43_12010	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
HPS43_12015	ENOG4105DK0	Indole-3-glycerol phosphate synthase
HPS43_12020	ENOG4108I0Q	anthranilate phosphoribosyltransferase
HPS43_12025	ENOG4105DDQ	anthranilate synthase
HPS43_12035	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HPS43_12045	ENOG4105NWN	ApaG protein
HPS43_12055	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
HPS43_12060	ENOG4105T95	Thiol disulfide interChange protein
HPS43_12070	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
HPS43_12080	ENOG4105C3M	thioredoxin reductase
HPS43_12085	ENOG4105F2Z	3-oxoadipate enol-lactonase
HPS43_12090	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
HPS43_12100	ENOG4105C32	Amino acid ABC transporter (Permease)
HPS43_12105	ENOG4105C32	Amino acid ABC transporter (Permease)
HPS43_12110	ENOG4105C0Z	ABC transporter
HPS43_12115	ENOG4108IV0	ABC, transporter
HPS43_12120	ENOG4105DCY	Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity)
HPS43_12135	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
HPS43_12145	ENOG4105RE0	Asp Glu hydantoin racemase
HPS43_12150	ENOG4106NZI	LysR family Transcriptional regulator
HPS43_12165	ENOG4107QNJ	CoA-transferase subunit B
HPS43_12180	ENOG4105E39	Enoyl-CoA hydratase
HPS43_12195	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
HPS43_12200	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HPS43_12210	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HPS43_12215	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
HPS43_12220	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
HPS43_12230	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
HPS43_12240	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
HPS43_12245	ENOG4105C25	Primosomal protein n'
HPS43_12250	ENOG4105C4R	Atp-dependent dna helicase
HPS43_12255	ENOG4105E7U	AraC family transcriptional regulator
HPS43_12265	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HPS43_12275	ENOG4105ECQ	AraC Family Transcriptional Regulator
HPS43_12280	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
HPS43_12285	ENOG4105CSR	polyphosphate kinase 2
HPS43_12290	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
HPS43_12300	ENOG4108JQ7	(ABC) transporter
HPS43_12305	ENOG4105C3U	ABC transporter
HPS43_12320	ENOG4105DEF	Extracellular solute-binding protein, family 5
HPS43_12325	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
HPS43_12335	ENOG4105EMY	transcriptional regulator
HPS43_12340	ENOG4105DEF	Extracellular solute-binding protein, family 5
HPS43_12350	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HPS43_12355	ENOG41060WC	Enoyl-CoA hydratase
HPS43_12360	ENOG4105E39	Enoyl-CoA hydratase
HPS43_12370	ENOG4105KBX	Transcriptional regulator, TetR family
HPS43_12385	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HPS43_12400	ENOG4107XZQ	multidrug resistance protein
HPS43_12415	ENOG4108ZHJ	Organic hydroperoxide resistance protein
HPS43_12420	ENOG4105EJC	lysr family transcriptional regulator
HPS43_12430	ENOG4108KPJ	rna polymerase sigma factor
HPS43_12435	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HPS43_12440	ENOG4108Z9W	Outer membrane porin
HPS43_12455	ENOG4105ERH	Fumarylacetoacetate hydrolase
HPS43_12465	ENOG4105C32	Amino acid ABC transporter (Permease)
HPS43_12470	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
HPS43_12475	ENOG4105C2J	ABC transporter
HPS43_12480	ENOG4108IV0	ABC, transporter
HPS43_12490	ENOG4107XBN	GntR Family Transcriptional Regulator
HPS43_12500	ENOG4105DND	Transcriptional regulator
HPS43_12510	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
HPS43_12520	ENOG4105D9M	gamma-glutamylcysteine synthetase
HPS43_12550	ENOG4105DG4	malate L-lactate dehydrogenase
HPS43_12555	ENOG4108JQ1	Dehydrogenase
HPS43_12565	ENOG4105CTX	dehydratase
HPS43_12570	ENOG4105VP7	SAF domain protein
HPS43_12575	ENOG4105FDP	GntR family transcriptional regulator
HPS43_12580	ENOG4105DWV	Homoserine O-trans-acetylase
HPS43_12585	ENOG4105DWV	Homoserine O-trans-acetylase
HPS43_12590	ENOG4105EYM	Major Facilitator superfamily
HPS43_12600	ENOG4105EN6	Membrane
HPS43_12605	ENOG4105DRR	Transcriptional regulator, GntR family
HPS43_12620	ENOG4105P4J	Allophanate hydrolase, subunit 1
HPS43_12630	ENOG4107RSM	transcriptional regulator
HPS43_12640	ENOG4108JQ1	Dehydrogenase
HPS43_12655	ENOG4105E3B	Multicopper oxidase
HPS43_12675	ENOG4105BZU	Histidine kinase
HPS43_12680	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HPS43_12685	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HPS43_12700	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
HPS43_12710	ENOG4107Z67	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
HPS43_12715	ENOG4105DFG	type I secretion outer membrane protein
HPS43_12720	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
HPS43_12725	ENOG4105DWF	phosphomethylpyrimidine kinase
HPS43_12730	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
HPS43_12735	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
HPS43_12740	ENOG4105D05	Receptor
HPS43_12745	ENOG4105C3R	Methionine synthase
HPS43_12750	ENOG4107YCY	Transcriptional regulator
HPS43_12765	ENOG4105CPQ	Dehydrogenase
HPS43_12770	ENOG4105E5Q	amino acid AbC transporter
HPS43_12775	ENOG4105EAD	ABC transporter
HPS43_12780	ENOG4105CDA	abc transporter atp-binding protein
HPS43_12785	ENOG4105CXK	mandelate racemase muconate lactonizing
HPS43_12790	ENOG4105DEI	Mannitol dehydrogenase
HPS43_12805	ENOG4105CEN	a g-specific adenine glycosylase
HPS43_12820	ENOG4105ECQ	AraC Family Transcriptional Regulator
HPS43_12830	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
HPS43_12835	ENOG4105CAK	Cell division ATP-binding protein ftsE
HPS43_12840	ENOG4107QXX	ABC transporter
HPS43_12845	ENOG4105EZ7	amino acid ABC transporter
HPS43_12850	ENOG4105DRP	amino acid AbC transporter
HPS43_12855	ENOG4105CDA	abc transporter atp-binding protein
HPS43_12875	ENOG4108IV0	ABC, transporter
HPS43_12880	ENOG4105C2J	ABC transporter
HPS43_12885	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
HPS43_12890	ENOG4105C32	Amino acid ABC transporter (Permease)
HPS43_12900	ENOG4105MSY	salicylate hydroxylase
HPS43_12905	ENOG4105CBX	hi0933 family
HPS43_12910	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
HPS43_12915	ENOG4105CQC	Prephenate dehydratase
HPS43_12950	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HPS43_12960	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
HPS43_12965	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
HPS43_12970	ENOG4108Q9V	regulatoR
HPS43_12985	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
HPS43_12990	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
HPS43_12995	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
HPS43_13020	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
HPS43_13040	ENOG4105EG2	ABC transporter, permease
HPS43_13045	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
HPS43_13050	ENOG4108IJ9	(ABC) transporter
HPS43_13070	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
HPS43_13090	ENOG4105C32	Amino acid ABC transporter (Permease)
HPS43_13095	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
HPS43_13100	ENOG4105C0Z	ABC transporter
HPS43_13105	ENOG4108IV0	ABC, transporter
HPS43_13125	ENOG4105BZU	Histidine kinase
HPS43_13130	ENOG4105BZU	Histidine kinase
HPS43_13145	ENOG4108UKI	Enoyl-CoA hydratase
HPS43_13170	ENOG4105ECQ	AraC Family Transcriptional Regulator
HPS43_13185	ENOG4105FUY	alpha subunit
HPS43_13190	ENOG4108SBK	dioxygenase, subunit beta
HPS43_13195	ENOG4105D3W	isochorismatase
HPS43_13200	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
HPS43_13210	ENOG4105E4C	Lytic transglycosylase catalytic
HPS43_13215	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
HPS43_13220	ENOG4107RZ7	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
HPS43_13230	ENOG4105VCQ	rubredoxin
HPS43_13235	ENOG4108UJU	UPF0301 protein
HPS43_13240	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
HPS43_13250	ENOG4105CD3	dihydroorotase
HPS43_13255	ENOG4108Z20	Acyl-transferase
HPS43_13270	ENOG4105JSC	dimethylmenaquinone methyltransferase
HPS43_13280	ENOG4106PMH	Extracellular solute-binding protein family 3
HPS43_13285	ENOG4105E5Q	amino acid AbC transporter
HPS43_13295	ENOG4105CDA	abc transporter atp-binding protein
HPS43_13300	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
HPS43_13310	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
HPS43_13315	ENOG4105E2X	shikimate dehydrogenase
HPS43_13325	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HPS43_13330	ENOG4107Z33	ABC transporter, permease
HPS43_13340	ENOG4105DHQ	Histidine kinase
HPS43_13355	ENOG4105IPS	esterase
HPS43_13360	ENOG4105DFU	Cell wall formation (By similarity)
HPS43_13365	ENOG4107QX9	Thiol disulfide interChange protein
HPS43_13370	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
HPS43_13375	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
HPS43_13380	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HPS43_13385	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HPS43_13395	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
HPS43_13420	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
HPS43_13425	ENOG4108IQD	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity)
HPS43_13440	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HPS43_13445	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HPS43_13455	ENOG4108YXU	transcriptional regulator AsnC family
HPS43_13470	ENOG4105DND	Transcriptional regulator
HPS43_13485	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HPS43_13490	ENOG4105CD5	CoA-binding domain protein
HPS43_13495	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
HPS43_13500	ENOG4105EFP	binding-protein-dependent transport systems inner membrane Component
HPS43_13520	ENOG4105N42	UPF0307 protein
HPS43_13525	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
HPS43_13530	ENOG4105CH5	extracellular solute-binding protein, family 7
HPS43_13540	ENOG4105C32	Amino acid ABC transporter (Permease)
HPS43_13545	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
HPS43_13550	ENOG4105C0Z	ABC transporter
HPS43_13555	ENOG4108IV0	ABC, transporter
HPS43_13560	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
HPS43_13565	ENOG4108UJD	30S ribosomal protein S9
HPS43_13570	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
HPS43_13580	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
HPS43_13595	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
HPS43_13605	ENOG4105N14	lysine exporter protein LysE YggA
HPS43_13610	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HPS43_13615	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
HPS43_13630	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HPS43_13645	ENOG4105CYN	Serine protein kinase
HPS43_13650	ENOG4106AKX	UPF0229 protein
HPS43_13655	ENOG4105ED1	spovr family
HPS43_13665	ENOG4105ETT	transcriptional Regulator, LysR family
HPS43_13670	ENOG4105MDS	4-oxalocrotonate tautomerase
HPS43_13680	ENOG4108Z33	Thiol disulfide Interchange Protein
HPS43_13870	ENOG4105EMN	RNA polymerase sigma factor
HPS43_13895	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HPS43_13900	ENOG4105JGF	anti-sigma regulatory factor serine threonine protein kinase
HPS43_13905	ENOG41083UI	stage II sporulation protein
HPS43_13920	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
HPS43_13940	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
HPS43_13945	ENOG4105E9H	Lytic Murein transglycosylase
HPS43_13950	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HPS43_13955	ENOG4105D1A	Methyltransferase
HPS43_13960	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HPS43_13970	ENOG4105BZS	acriflavin resistance protein
HPS43_13975	ENOG4107RZZ	dna polymerase iii epsilon subunit
HPS43_13990	ENOG4108UPT	UPF0178 protein
HPS43_14005	ENOG4105D6U	Sodium Glutamate Symporter
HPS43_14020	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
HPS43_14035	ENOG4105CR8	Transcriptional regulator
HPS43_14055	ENOG4105C32	Amino acid ABC transporter (Permease)
HPS43_14065	ENOG4108IV0	ABC, transporter
HPS43_14070	ENOG4105C0Z	ABC transporter
HPS43_14075	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HPS43_14085	ENOG4105CMU	LysR family (Transcriptional regulator
HPS43_14090	ENOG4105VAW	lrga family
HPS43_14095	ENOG41067MG	lrgb family
HPS43_14105	ENOG4105T38	integral membrane protein
HPS43_14110	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HPS43_14125	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HPS43_14135	ENOG4108YXU	transcriptional regulator AsnC family
HPS43_14150	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
HPS43_14155	ENOG4105EHG	Permease protein
HPS43_14165	ENOG4105KCK	Peptidoglycan-associated lipoprotein
HPS43_14170	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
HPS43_14185	ENOG4105E02	MotA TolQ exbB proton channel
HPS43_14190	ENOG4107YD3	Thioesterase
HPS43_14195	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
HPS43_14225	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
HPS43_14230	ENOG4105EXG	Transcriptional regulator
HPS43_14240	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HPS43_14245	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HPS43_14285	ENOG4105C01	Dihydroxy-acid dehydratase
HPS43_14290	ENOG4105W2Z	cytochrome C, class I
HPS43_14295	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HPS43_14305	ENOG4105EW9	transcriptional regulator AsnC family
HPS43_14345	ENOG4105ETT	transcriptional Regulator, LysR family
HPS43_14355	ENOG4105CH2	amidohydrolase
HPS43_14360	ENOG4105EKE	dihydroorotase
HPS43_14365	ENOG4105C5H	ABC transporter
HPS43_14375	ENOG4108V6E	Cell division protein mraZ
HPS43_14380	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
HPS43_14385	ENOG4105N8N	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
HPS43_14390	ENOG4105CJN	penicillin-binding protein
HPS43_14395	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HPS43_14400	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
HPS43_14405	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
HPS43_14415	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HPS43_14420	ENOG4105DFU	Cell wall formation (By similarity)
HPS43_14425	ENOG4105CPF	Cell wall formation (By similarity)
HPS43_14430	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
HPS43_14435	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HPS43_14440	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
HPS43_14445	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HPS43_14455	ENOG4105DR5	peptidase
HPS43_14460	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HPS43_14480	ENOG4105C7K	acetolactate synthase
HPS43_14495	ENOG4108XM1	transcriptional regulator AsnC family
HPS43_14510	ENOG4105CJW	magnesium transporter
HPS43_14515	ENOG4105NAU	thioesterase Superfamily protein
HPS43_14520	ENOG4105HMI	Membrane
HPS43_14530	ENOG4105CH2	amidohydrolase
HPS43_14535	ENOG4105CEY	Amp-dependent synthetase and ligase
HPS43_14540	ENOG4105ECY	inositol monophosphatase
HPS43_14545	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
HPS43_14550	ENOG4105CJQ	hydrolase, family 31
HPS43_14555	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HPS43_14560	ENOG4108UMI	ABC transporter, permease
HPS43_14565	ENOG4105D01	(LipO)protein
HPS43_14575	ENOG4108SF5	RNA Polymerase
HPS43_14580	ENOG4108S3W	Anti-feci sigma factor, fecr
HPS43_14600	ENOG4105C8Q	Methyl-accepting chemotaxis
HPS43_14605	ENOG4106P55	Transcriptional regulator
HPS43_14615	ENOG41090R7	Ferric uptake
HPS43_14640	ENOG4108R3E	Dna-3-methyladenine glycosylase i
HPS43_14645	ENOG4105E0M	Sulfatase
HPS43_14650	ENOG41066T0	asmA family
HPS43_14665	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
HPS43_14680	ENOG4106A3M	Cytochrome p-450
HPS43_14730	ENOG4105KZX	Pterin carbinolamine dehydratase
HPS43_14745	ENOG4105E2Q	3-(3-hydroxy-phenyl)propionate hydroxylase
HPS43_14755	ENOG4108S0S	Nucleotidyl transferase
HPS43_14760	ENOG4105EHM	Aminoglycoside phosphotransferase
HPS43_14770	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
HPS43_14775	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HPS43_14780	ENOG4105BZW	Glycerate kinase
HPS43_14785	ENOG4105CA9	Pyruvate kinase
HPS43_14795	ENOG4107QPN	acyl-Coa dehydrogenase
HPS43_14800	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HPS43_14820	ENOG4105E9Q	Acyl-transferase
HPS43_14825	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
HPS43_14830	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
HPS43_14835	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
HPS43_14850	ENOG4107SDU	Methyl-accepting chemotaxis
HPS43_14860	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HPS43_14870	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
HPS43_14885	ENOG4105EA8	2-Nitropropane dioxygenase
HPS43_14895	ENOG4105CEY	Amp-dependent synthetase and ligase
HPS43_14900	ENOG4105CHU	acetyl-coa acetyltransferase
HPS43_14910	ENOG4105CC9	acyl-Coa dehydrogenase
HPS43_14915	ENOG4105C1G	acyl-Coa dehydrogenase
HPS43_14920	ENOG4108UKI	Enoyl-CoA hydratase
HPS43_14930	ENOG4108M9J	MaoC like domain protein
HPS43_14940	ENOG4105CI0	Citrate lyase
HPS43_14945	ENOG4108MGF	sugar kinase
HPS43_14950	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HPS43_14955	ENOG4105DJ0	Poly(A) Polymerase
HPS43_14965	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
HPS43_14970	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
HPS43_14980	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HPS43_14985	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
HPS43_14990	ENOG4105DQR	SNARE associated Golgi
HPS43_15000	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HPS43_15005	ENOG4105K8N	protein family UPF0079, ATPase
HPS43_15030	ENOG4105DUM	transcriptional regulator, lysR family
HPS43_15035	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HPS43_15040	ENOG4105CUB	amino acid
HPS43_15045	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HPS43_15055	ENOG4105CSU	acyl-Coa dehydrogenase
HPS43_15060	ENOG4107RSM	transcriptional regulator
HPS43_15065	ENOG4105ERH	Fumarylacetoacetate hydrolase
HPS43_15100	ENOG4105CR8	Transcriptional regulator
HPS43_15110	ENOG4105D5U	fad dependent oxidoreductase
HPS43_15120	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
HPS43_15135	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
HPS43_15140	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HPS43_15145	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HPS43_15150	ENOG4106NZI	LysR family Transcriptional regulator
HPS43_15170	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HPS43_15200	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HPS43_15205	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HPS43_15215	ENOG4105CW7	secretion protein, HlyD family
HPS43_15220	ENOG4105CUZ	uba thif-type nad fad binding protein
HPS43_15255	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HPS43_15265	ENOG4108UHU	Aldolase
HPS43_15280	ENOG4105K64	Glycosyl transferase, family 2
HPS43_15285	ENOG4108IV0	ABC, transporter
HPS43_15290	ENOG4105C0Z	ABC transporter
HPS43_15305	ENOG4105CHR	reductase
HPS43_15310	ENOG4106IPI	cyclase, family
HPS43_15325	ENOG4105CEY	Amp-dependent synthetase and ligase
HPS43_15330	ENOG4108UKV	benzoate 1,2-dioxygenase
HPS43_15335	ENOG4105FUY	alpha subunit
HPS43_15360	ENOG4105DEF	Extracellular solute-binding protein, family 5
HPS43_15365	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HPS43_15370	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HPS43_15375	ENOG4105C3U	ABC transporter
HPS43_15380	ENOG4108JQ7	(ABC) transporter
HPS43_15400	ENOG4108AQF	aminoglycoside N(3)-acetyltransferase
HPS43_15405	ENOG4105C5H	ABC transporter
HPS43_15430	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
HPS43_15435	ENOG4107QMS	site-determining protein
HPS43_15440	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
HPS43_15445	ENOG4105CX6	glutaminyL-tRNA synthetase
HPS43_15455	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HPS43_15460	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HPS43_15480	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
HPS43_15490	ENOG4105ECP	epimerase
HPS43_15495	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
HPS43_15515	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HPS43_15520	ENOG4105D0A	hydroxylase
HPS43_15530	ENOG4107RAQ	aminopeptidase
HPS43_15545	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
HPS43_15550	ENOG4108Z9W	Outer membrane porin
HPS43_15565	ENOG4105ERG	peptidase m48, ste24p
HPS43_15585	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HPS43_15605	ENOG4105EYM	Major Facilitator superfamily
HPS43_15610	ENOG4107ZSV	Receptor
HPS43_15620	ENOG4105C1J	atp-dependent rna helicase
HPS43_15635	ENOG4107TH8	cina domain protein
HPS43_15640	ENOG41069M3	Transcriptional regulator
HPS43_15655	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
HPS43_15660	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
HPS43_15665	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
HPS43_15785	ENOG4107YH6	single-stranded DNA-binding protein
HPS43_15790	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HPS43_15805	ENOG4105W1Y	Transcriptional regulator
HPS43_15815	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HPS43_15900	ENOG4105CAU	Arsenical resistance protein, ArsH
HPS43_15905	ENOG4105K89	arsenate reductase
HPS43_15910	ENOG4105D6J	arsenicaL-resistance protein
HPS43_15920	ENOG41085FC	arsR family transcriptional regulator
HPS43_15985	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
HPS43_15995	ENOG4105VT3	DNA binding domain protein, excisionase family
HPS43_16050	ENOG4105W5Q	DNA repair protein (RadC
HPS43_16115	ENOG4108Z4X	TRANSCRIPTIONal
HPS43_16150	ENOG4105CSR	polyphosphate kinase 2
HPS43_16155	ENOG4105C59	p-type ATPase
HPS43_16170	ENOG4105HA9	of methanol dehydrogenase type
HPS43_16180	ENOG4105CY0	Metallo-Beta-Lactamase
HPS43_16185	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
HPS43_16190	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HPS43_16205	ENOG4105C5I	Dehydrogenase
HPS43_16225	ENOG4108IXY	short-chain dehydrogenase reductase
HPS43_16235	ENOG4107QRI	Phosphoketolase
HPS43_16240	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HPS43_16245	ENOG4105W1Y	Transcriptional regulator
HPS43_16250	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HPS43_16270	ENOG4105GR3	Histidine kinase
HPS43_16275	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HPS43_16280	ENOG4105E3B	Multicopper oxidase
HPS43_16320	ENOG4107RSM	transcriptional regulator
HPS43_16350	ENOG4108IJF	Heavy metal efflux pump, CzcA
HPS43_16385	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HPS43_16390	ENOG41090R7	Ferric uptake
HPS43_16395	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HPS43_16405	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
HPS43_16410	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
HPS43_16420	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HPS43_16430	ENOG4105CFG	Acts as a chaperone (By similarity)
HPS43_16435	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HPS43_16450	ENOG4108YYQ	gCN5-related N-acetyltransferase
HPS43_16470	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HPS43_16505	ENOG4105C8Q	Methyl-accepting chemotaxis
HPS43_16510	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HPS43_16525	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
HPS43_16530	ENOG4105C08	Histidine kinase
HPS43_16535	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
HPS43_16540	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
HPS43_16545	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
HPS43_16560	ENOG4107QN1	sodium solute
HPS43_16570	ENOG4105C98	muts2 protein
HPS43_16575	ENOG4105C3M	thioredoxin reductase
HPS43_16580	ENOG4105CNU	cell division protein FtsK
HPS43_16585	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
HPS43_16590	ENOG4105KME	endoribonuclease L-psp
HPS43_16600	ENOG4105C2X	Arabinose 5-phosphate isomerase
HPS43_16640	ENOG4105D1H	recombination factor protein RarA
HPS43_16645	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
HPS43_16685	ENOG4105DIA	mandelate racemase muconate lactonizing
HPS43_16690	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HPS43_16710	ENOG4108IPW	abc transporter atp-binding protein
HPS43_16750	ENOG4105DTD	Dehydrogenase
HPS43_16755	ENOG4105D1Q	UPF0246 protein
HPS43_16765	ENOG4105C7K	acetolactate synthase
HPS43_16770	ENOG4108ZP8	Acetolactate synthase small subunit
HPS43_16775	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
HPS43_16780	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
HPS43_16790	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
HPS43_16795	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HPS43_16810	ENOG4105C7B	Threonine dehydratase
HPS43_16820	ENOG4105ES4	Nitrilase
HPS43_16830	ENOG4105E7U	AraC family transcriptional regulator
HPS43_16855	ENOG4105CP7	Triose-phosphate isomerase
HPS43_16860	ENOG4105NTZ	Preprotein translocase subunit SecG
HPS43_16890	ENOG4108SUT	Major Facilitator Superfamily
HPS43_16905	ENOG4105C8Q	Methyl-accepting chemotaxis
HPS43_16925	ENOG4105HD0	Transcriptional regulator of molybdate metabolism, LysR family
HPS43_16960	ENOG4108NFJ	ABC transporter
HPS43_16990	ENOG4108SF5	RNA Polymerase
HPS43_17000	ENOG4105CNM	Receptor
HPS43_17005	ENOG4108SF5	RNA Polymerase
HPS43_17010	ENOG4108S3W	Anti-feci sigma factor, fecr
HPS43_17035	ENOG4105ECM	Sensor protein basS pmrB
HPS43_17045	ENOG4105D4T	Citrate transporter
HPS43_17050	ENOG4105CHR	reductase
HPS43_17070	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HPS43_17075	ENOG4105CQZ	Histidine kinase
HPS43_17095	ENOG4105FJH	Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity)
HPS43_17100	ENOG4105XDF	Protein of unknown function (DUF1272)
HPS43_17105	ENOG4105CKW	Inner membrane protein yedI
HPS43_17110	ENOG4105ETT	transcriptional Regulator, LysR family
HPS43_17120	ENOG4105GAV	receptor
HPS43_17145	ENOG4108JQ6	ABC transporter
HPS43_17155	ENOG4106R87	Extracellular solute-binding protein, family 5
HPS43_17175	ENOG4105BZS	acriflavin resistance protein
HPS43_17190	ENOG4105C94	Transporter
HPS43_17195	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
HPS43_17200	ENOG4105BZS	acriflavin resistance protein
HPS43_17215	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HPS43_17220	ENOG4105BZS	acriflavin resistance protein
HPS43_17225	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HPS43_17230	ENOG4108IG5	Transcriptional regulator
HPS43_17235	ENOG4108R4R	Iron-regulated virulence regulatory protein
HPS43_17255	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
HPS43_17280	ENOG4108Z9W	Outer membrane porin
HPS43_17285	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HPS43_17290	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HPS43_17295	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HPS43_17300	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HPS43_17315	ENOG4108IEH	NADH dehydrogenase subunit g
HPS43_17320	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
HPS43_17325	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HPS43_17330	ENOG4105DF2	NADH dehydrogenase subunit j
HPS43_17335	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HPS43_17345	ENOG4105C8S	subunit m
HPS43_17350	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HPS43_17360	ENOG4108ESX	Receptor
HPS43_17365	ENOG4105EAC	phosphoserine phosphatase
HPS43_17370	ENOG4108JA2	transcriptioN-repair coupling factor
HPS43_17375	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
HPS43_17380	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
HPS43_17390	ENOG4108X7C	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
HPS43_17395	ENOG4105D3R	alkyl hydroperoxide reductase
HPS43_17400	ENOG4105E0F	Histidine kinase
HPS43_17410	ENOG41072GX	Peptidase M22 Glycoprotease
HPS43_17415	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
HPS43_17420	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
HPS43_17425	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
HPS43_17435	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HPS43_17440	ENOG4107TF3	peptidylprolyl cis-trans isomerase
HPS43_17450	ENOG4107835	probably involved in intracellular septation (By similarity)
HPS43_17455	ENOG4105E0X	reductase
HPS43_17460	ENOG4108JJB	ABC transporter
HPS43_17465	ENOG4107QCX	Transporter
HPS43_17470	ENOG4107ZYJ	bioY protein
HPS43_17485	ENOG4105C0Z	ABC transporter
HPS43_17490	ENOG4108IV0	ABC, transporter
HPS43_17500	ENOG4105HSS	phospholipase C
HPS43_17520	ENOG4105C32	Amino acid ABC transporter (Permease)
HPS43_17530	ENOG4108IV0	ABC, transporter
HPS43_17535	ENOG4105C0Z	ABC transporter
HPS43_17540	ENOG4105CSM	endonuclease III
HPS43_17545	ENOG4108R3D	Electron transport complex
HPS43_17555	ENOG4105DP0	ferredoxin-NADP reductase
HPS43_17560	ENOG4108Z4U	Ferredoxin
HPS43_17565	ENOG4107RH7	Nicotinate phosphoribosyltransferase
HPS43_17570	ENOG4105M4H	endoribonuclease L-psp
HPS43_17580	ENOG4105EXZ	Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity)
HPS43_17585	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HPS43_17590	ENOG4105CSH	Transporter
HPS43_17595	ENOG4105CWC	Acetylornithine deacetylase
HPS43_17605	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
HPS43_17610	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
HPS43_17615	ENOG41061N2	exported protein
HPS43_17620	ENOG4107QQB	Ribonuclease E
HPS43_17625	ENOG4105EI2	Pseudouridine synthase
HPS43_17630	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HPS43_17635	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
HPS43_17640	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
HPS43_17650	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HPS43_17655	ENOG4108UHJ	MAF-like protein
HPS43_17660	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
HPS43_17665	ENOG4105VGS	50s ribosomal protein l32
HPS43_17675	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HPS43_17680	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HPS43_17685	ENOG4105CHR	reductase
HPS43_17690	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HPS43_17695	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HPS43_17705	ENOG4105EMN	RNA polymerase sigma factor
HPS43_17720	ENOG4105C0H	protease
HPS43_17725	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
HPS43_17730	ENOG4105C3F	Signal peptidase i
HPS43_17735	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
HPS43_17740	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
HPS43_17745	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
HPS43_17795	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HPS43_17805	ENOG4108MP6	LysR family Transcriptional regulator
HPS43_17815	ENOG4105C26	Dehydrogenase
HPS43_17820	ENOG4107R11	Transcriptional regulator
HPS43_17830	ENOG4105K4H	Nlp p60 protein
HPS43_17835	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HPS43_17840	ENOG4108ZJF	Glcg protein
HPS43_17855	ENOG4108Q5Y	Membrane
HPS43_17860	ENOG4105C5W	Aldolase
HPS43_17865	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HPS43_17885	ENOG4107SRH	Nad-dependent epimerase dehydratase
HPS43_17890	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
HPS43_17910	ENOG4107YB6	acetyltransferase, (GNAT) family
HPS43_17920	ENOG4105D44	asparaginase
HPS43_17925	ENOG4108JQ6	ABC transporter
HPS43_17930	ENOG4105DEF	Extracellular solute-binding protein, family 5
HPS43_17965	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HPS43_17975	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HPS43_17990	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
HPS43_18000	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HPS43_18030	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
HPS43_18035	ENOG4108YXA	Membrane
HPS43_18040	ENOG4105DXD	2-methylcitrate dehydratase
HPS43_18045	ENOG4105BZN	citrate synthase
HPS43_18050	ENOG4105CR4	methylisocitrate lyase
HPS43_18055	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
HPS43_18060	ENOG4105FDP	GntR family transcriptional regulator
HPS43_18065	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
HPS43_18070	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
HPS43_18080	ENOG4105E33	succinate dehydrogenase
HPS43_18085	ENOG41060IS	Flavinator of succinate dehydrogenase
HPS43_18090	ENOG4105BZN	citrate synthase
HPS43_18105	ENOG4105C6K	Malic enzyme
HPS43_18110	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
HPS43_18115	ENOG4105EPD	Oligopeptide transporter, Opt family
HPS43_18120	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HPS43_18135	ENOG4105K6H	D-cysteine desulfhydrase
HPS43_18140	ENOG4108XM1	transcriptional regulator AsnC family
HPS43_18145	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
HPS43_18150	ENOG4105C7S	Dehydrogenase
HPS43_18155	ENOG4107QN2	dihydrolipoyl dehydrogenase
HPS43_18160	ENOG4105D6Z	AFG1 family ATPase
HPS43_18165	ENOG4108SF5	RNA Polymerase
HPS43_18170	ENOG4108S3W	Anti-feci sigma factor, fecr
HPS43_18175	ENOG4105E0K	tonB-dependent siderophore receptor
HPS43_18210	ENOG4105BZM	domain protein
HPS43_18215	ENOG4105DVT	helicase
HPS43_18220	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HPS43_18225	ENOG4105C34	Pseudouridine synthase
HPS43_18230	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
HPS43_18235	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
HPS43_18240	ENOG4105CHR	reductase
HPS43_18245	ENOG4108NVM	synthesis repressor PhaR
HPS43_18270	ENOG4105D5K	Hemolysin activator protein
HPS43_18290	ENOG4105JAB	phenazine biosynthesis protein, phzf family
HPS43_18295	ENOG4105K3G	Periplasmic Protein
HPS43_18305	ENOG4105VDW	Csbd family
HPS43_18320	ENOG4105BZ1	(ABC) transporter
HPS43_18335	ENOG4105ED9	Protein of unknown function (DUF455)
HPS43_18340	ENOG4108RPX	mosc domain containing protein
HPS43_18345	ENOG4105CVE	Lytic murein transglycosylase
HPS43_18360	ENOG4105C1G	acyl-Coa dehydrogenase
HPS43_18370	ENOG4108IQD	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity)
HPS43_18380	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
HPS43_18390	ENOG4108XTA	Together with AlgI and AlgF, forms an inner membrane complex which probably interacts with the alginate polymerization- transport complex and adds acetyl groups at the O-2 and O-3 positions of polymannuronic acid. Acetylation of alginate
HPS43_18400	ENOG410802X	bacteriophage n4 adsorption protein b
HPS43_18425	ENOG4105F27	Major Facilitator
HPS43_18430	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HPS43_18435	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
HPS43_18440	ENOG4105UYK	outer membrane protein a
HPS43_18445	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HPS43_18450	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
HPS43_18455	ENOG4105CQC	Prephenate dehydratase
HPS43_18470	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
HPS43_18475	ENOG4105CAT	Cytidine monophosphate kinase
HPS43_18480	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HPS43_18495	ENOG4105CFV	Tetratricopeptide repeat protein
HPS43_18500	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
HPS43_18505	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
HPS43_18515	ENOG4105C6T	cysteine synthase
HPS43_18535	ENOG4105CVE	Lytic murein transglycosylase
HPS43_18545	ENOG4105BZJ	Electron transfer flavoprotein
HPS43_18550	ENOG4105C10	Electron transfer flavoprotein
HPS43_18570	ENOG4105CSU	acyl-Coa dehydrogenase
HPS43_18575	ENOG4105D3R	alkyl hydroperoxide reductase
HPS43_18580	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
HPS43_18585	ENOG4108I5D	sulfate abc transporter
HPS43_18610	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
HPS43_18630	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
HPS43_18635	ENOG4105P8F	nudix hydrolase
HPS43_18640	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
HPS43_18645	ENOG4105D0M	Protease HtpX homolog
HPS43_18650	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
HPS43_18660	ENOG4105V9J	phenylacetic acid degradation operon negative regulatory protein
HPS43_18665	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
HPS43_18670	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
HPS43_18675	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
HPS43_18680	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
HPS43_18685	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
HPS43_18690	ENOG4105C26	Dehydrogenase
HPS43_18695	ENOG4108UKI	Enoyl-CoA hydratase
HPS43_18700	ENOG4108ZJI	phenylacetic acid degradation protein
HPS43_18710	ENOG4107QI1	Mate efflux family protein
HPS43_18725	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
HPS43_18730	ENOG4107VWA	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity)
HPS43_18735	ENOG4105W5Q	DNA repair protein (RadC
HPS43_18745	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
HPS43_18750	ENOG4108RXX	maleylacetoacetate isomerase
HPS43_18755	ENOG4105C0H	protease
HPS43_18760	ENOG4105DHQ	Histidine kinase
HPS43_18765	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HPS43_18780	ENOG4105CKI	cobalamin synthesis protein
HPS43_18785	ENOG4105CKI	cobalamin synthesis protein
HPS43_18790	ENOG4105EJC	lysr family transcriptional regulator
HPS43_18805	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
HPS43_18810	ENOG4105FE9	pseudouridine synthase
HPS43_18815	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
HPS43_18820	ENOG4105CHV	Transcription elongation factor NusA
HPS43_18825	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
HPS43_18830	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
HPS43_18835	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HPS43_18840	ENOG4105CI3	gtp-binding protein typa
HPS43_18865	ENOG4107RT5	aminobenzoyl-glutamate utilization protein B
HPS43_18870	ENOG4108URH	decarboxylase
HPS43_18875	ENOG4105C2M	dna polymerase I
HPS43_18885	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
HPS43_18890	ENOG4105EAM	Na Pi-cotransporter
HPS43_18895	ENOG4105EJQ	L-serine dehydratase
HPS43_18900	ENOG4105D0M	Protease HtpX homolog
HPS43_18910	ENOG4105KHC	sulfurtransferase
HPS43_18920	ENOG4105DUM	transcriptional regulator, lysR family
HPS43_18925	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HPS43_18935	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
HPS43_18970	ENOG41082UU	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HPS43_18975	ENOG4105CTB	Polyprenyl synthetase
HPS43_18985	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
HPS43_18990	ENOG4105NX3	Membrane
HPS43_18995	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
HPS43_19005	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
HPS43_19010	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
HPS43_19020	ENOG4105CDU	Replicative dna helicase
HPS43_19030	ENOG4105DHU	Bile acid
HPS43_19035	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
HPS43_19045	ENOG4105EW9	transcriptional regulator AsnC family
HPS43_19070	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HPS43_19120	ENOG4105CXT	aspartate transcarbamylase
HPS43_19140	ENOG4105CSH	Transporter
HPS43_19145	ENOG4105DHQ	Histidine kinase
HPS43_19155	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
HPS43_19160	ENOG4108004	Modulates RecA activity (By similarity)
HPS43_19165	ENOG4105DZ2	Transcriptional regulator
HPS43_19185	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
HPS43_19190	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
HPS43_19195	ENOG4108ZCF	integral membrane protein
HPS43_19200	ENOG4108ZCF	integral membrane protein
HPS43_19205	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
HPS43_19225	ENOG4105F0N	pyrophosphate phospho-hydrolase
HPS43_19250	ENOG4105CHR	reductase
HPS43_19255	ENOG4105C0Z	ABC transporter
HPS43_19260	ENOG4108IV0	ABC, transporter
HPS43_19265	ENOG4105C32	Amino acid ABC transporter (Permease)
HPS43_19285	ENOG4108IAB	Phoh family
HPS43_19290	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HPS43_19300	ENOG4105CHM	Aminotransferase
HPS43_19305	ENOG4105D6E	homoserine dehydrogenase
HPS43_19320	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
HPS43_19325	ENOG4105CD8	aminopeptidase N
HPS43_19335	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
HPS43_19340	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
HPS43_19345	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HPS43_19350	ENOG4105CQB	FAD linked oxidase domain protein
HPS43_19355	ENOG4105CQB	FAD linked oxidase domain protein
HPS43_19360	ENOG4105EU8	FAD linked oxidase domain protein
HPS43_19365	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
HPS43_19370	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HPS43_19375	ENOG4105W8H	transhydrogenase (subunit alpha
HPS43_19380	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HPS43_19395	ENOG4105ETT	transcriptional Regulator, LysR family
HPS43_19400	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HPS43_19405	ENOG4105HF0	Membrane
HPS43_19410	ENOG4108U78	Glutathione S-transferase
HPS43_19415	ENOG4107QTF	adenylosuccinate lyase
HPS43_19420	ENOG4105T86	cytochrome C
HPS43_19450	ENOG4108REF	Sporulation integral membrane protein ytvi
HPS43_19460	ENOG4108MAJ	Membrane
HPS43_19565	ENOG4105BZU	Histidine kinase
HPS43_19575	ENOG4105RPH	Inner membrane protein YddG
HPS43_19610	ENOG41067HS	methyltransferase
HPS43_19620	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HPS43_19625	ENOG4105CBC	glutamate synthase
HPS43_19630	ENOG41066VF	YeeE YedE family protein
HPS43_19635	ENOG4105RK9	auxin efflux carrier
HPS43_19645	ENOG4108HPG	-acetyltransferase
HPS43_19665	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HPS43_19670	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HPS43_19675	ENOG4105C28	cystathionine
HPS43_19680	ENOG4107E2E	PKHD-type hydroxylase
HPS43_19685	ENOG4105K70	DNA-binding protein
HPS43_19710	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HPS43_19715	ENOG4105DHQ	Histidine kinase
HPS43_19720	ENOG4105DFH	Transport of potassium into the cell (By similarity)
HPS43_19725	ENOG4105CDH	Citrulline--aspartate ligase
HPS43_19730	ENOG4105C5Q	Transcriptional regulator
HPS43_19735	ENOG4105GAK	amidohydrolase 2
HPS43_19755	ENOG4108XEP	Alpha Beta Hydrolase Fold protein
HPS43_19760	ENOG4105DBV	ornithine carbamoyltransferase
HPS43_19765	ENOG4105C8Y	Acetylornithine aminotransferase
HPS43_19775	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HPS43_19785	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HPS43_19790	ENOG4105CV6	ABC transporter, permease
HPS43_19800	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
HPS43_19810	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HPS43_19815	ENOG4105F38	ABC transporter, permease
HPS43_19820	ENOG4105D38	putrescine abc transporter
HPS43_19830	ENOG4108RB4	3-methyladenine DNA glycosylase
HPS43_19840	ENOG4107QSV	RmuC domain protein
HPS43_19850	ENOG4105CSU	acyl-Coa dehydrogenase
HPS43_19860	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
HPS43_19865	ENOG4105HSS	phospholipase C
HPS43_19870	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
HPS43_19875	ENOG4108EKC	n-acetylglutamate synthase
HPS43_19880	ENOG4105CQ7	ATP-dependent helicase
HPS43_19885	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
HPS43_19900	ENOG4105C0B	DNA polymerase III (alpha subunit)
HPS43_19905	ENOG4105CPK	Glycosyl transferase (Group 1
HPS43_19910	ENOG4107BJW	polysaccharide deacetylase
HPS43_19915	ENOG4106WTF	Glycosyl transferase, family 2
HPS43_19920	ENOG4107T8Q	Glycosyl transferase (Group 1
HPS43_19925	ENOG4107BJW	polysaccharide deacetylase
HPS43_19935	ENOG4105KRS	Proteinase inhibitor
HPS43_19950	ENOG4105BZ1	(ABC) transporter
HPS43_19955	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
HPS43_19970	ENOG4106JH6	(LipO)protein
HPS43_19975	ENOG4105C03	ribonuclease
HPS43_20005	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HPS43_20015	ENOG4105CK2	sodium dicarboxylate symporter
HPS43_20025	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
HPS43_20030	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
HPS43_20035	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
HPS43_20045	ENOG4105C12	Phosphoribosylglycinamide synthetase
HPS43_20050	ENOG4105CDY	transcriptional regulatory protein
HPS43_20055	ENOG4105D7A	ATP-binding protein
HPS43_20060	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HPS43_20070	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HPS43_20075	ENOG4105CW7	secretion protein, HlyD family
HPS43_20080	ENOG4105ETP	RND efflux system, outer membrane lipoprotein
HPS43_20085	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
HPS43_20100	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
HPS43_20145	ENOG4105WPN	DNA integration recombination invertion protein
HPS43_20150	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
HPS43_20160	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
HPS43_20165	ENOG4105K63	Thioredoxin
HPS43_20170	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HPS43_20180	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HPS43_20185	ENOG4107Z3H	Transcriptional regulator, TetR family
HPS43_20195	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HPS43_20220	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
HPS43_20225	ENOG4105EV8	ectoine hydroxylase
HPS43_20230	ENOG4105QVC	MOSC domain-containing protein
HPS43_20235	ENOG4105KPY	Small multidrug resistance protein
HPS43_20250	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
HPS43_20265	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HPS43_20270	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
HPS43_20280	ENOG4105K5M	30s ribosomal protein S16
HPS43_20290	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
HPS43_20295	ENOG4105WBV	Transcriptional regulator
HPS43_20300	ENOG4106TNF	Periplasmic binding protein
HPS43_20305	ENOG4105E5Q	amino acid AbC transporter
HPS43_20310	ENOG4105CDA	abc transporter atp-binding protein
HPS43_20315	ENOG4105CJP	fad dependent oxidoreductase
HPS43_20320	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
HPS43_20325	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
HPS43_20330	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HPS43_20350	ENOG4105N21	Membrane
HPS43_20355	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HPS43_20360	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HPS43_20365	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HPS43_20370	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
HPS43_20375	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HPS43_20380	ENOG4107QJR	hflk protein
HPS43_20385	ENOG4105EPW	hflc protein
HPS43_20390	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
HPS43_20395	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
HPS43_20400	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
HPS43_20405	ENOG4105VCC	30S ribosomal protein S21
HPS43_20415	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HPS43_20425	ENOG4105CPK	Glycosyl transferase (Group 1
HPS43_20435	ENOG4105EXC	Acyl-transferase
HPS43_20495	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HPS43_20505	ENOG4107S2Z	UPF0761 membrane protein
HPS43_20515	ENOG4105CNG	UPF0061 protein
HPS43_20535	ENOG4105BZU	Histidine kinase
HPS43_20540	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
HPS43_20545	ENOG4105ERG	peptidase m48, ste24p
HPS43_20605	ENOG4108JJA	ABC, transporter
HPS43_20615	ENOG4105DFG	type I secretion outer membrane protein
HPS43_20635	ENOG4107QJH	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HPS43_20645	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
HPS43_20650	ENOG4105CH5	extracellular solute-binding protein, family 7
HPS43_20670	ENOG4105CPT	Alpha beta hydrolase
HPS43_20710	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HPS43_20715	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HPS43_20720	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
HPS43_20725	ENOG4105DIQ	Transcriptional regulator
HPS43_20730	ENOG4105FR1	rard protein
HPS43_20740	ENOG4105K8K	Cupin 2, conserved barrel
HPS43_20745	ENOG4108JQ6	ABC transporter
HPS43_20750	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HPS43_20755	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HPS43_20765	ENOG4105C26	Dehydrogenase
HPS43_20770	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
HPS43_20795	ENOG4105D4P	Coproporphyrinogen iii oxidase
HPS43_20800	ENOG41068CG	regulatoR
HPS43_20805	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
HPS43_20810	ENOG4105C22	threonyL-tRNA synthetase
HPS43_20815	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
HPS43_20830	ENOG41080Z8	PHOSPHOCARRIER protein
HPS43_20835	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
HPS43_20840	ENOG4105BZU	Histidine kinase
HPS43_20845	ENOG4108YZA	Nitrogen regulatory protein pii
HPS43_20855	ENOG4105W0Z	cytoplasmic protein
HPS43_20860	ENOG4105C0P	Mg chelatase subunit ChlI
HPS43_20865	ENOG4105VJV	50s ribosomal protein L35
HPS43_20870	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
HPS43_20875	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
HPS43_20880	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
HPS43_20940	ENOG4108R6G	acetyltransferase
HPS43_20975	ENOG4108YXU	transcriptional regulator AsnC family
HPS43_21035	ENOG4105E2Y	ABC, transporter
HPS43_21050	ENOG4105C5Q	Transcriptional regulator
HPS43_21055	ENOG4105DHU	Bile acid
HPS43_21065	ENOG4108JJ7	ABC transporter
HPS43_21070	ENOG4105CV8	reductase
HPS43_21085	ENOG4108R1E	Serine threonine protein phosphatase 1
HPS43_21090	ENOG4108JQC	penicillin-binding protein 1A
HPS43_21095	ENOG4105ID8	Transcriptional regulator, ARAC family
HPS43_21100	ENOG4105EU0	Major facilitator Superfamily
HPS43_21110	ENOG4105CND	Glycosyl transferase, family 2
HPS43_21115	ENOG4107BJW	polysaccharide deacetylase
HPS43_21120	ENOG4108TUY	outer membrane protein PgaA
HPS43_21125	ENOG4105BZU	Histidine kinase
HPS43_21145	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HPS43_21150	ENOG4105KTH	gatB Yqey
HPS43_21155	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HPS43_21160	ENOG4105C2D	reductase
HPS43_21200	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HPS43_21215	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HPS43_21240	ENOG4105KPV	Transcriptional regulator
HPS43_21245	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
HPS43_21250	ENOG4105SX7	Transporter
HPS43_21280	ENOG4105EXG	Transcriptional regulator
HPS43_21305	ENOG4108IY8	ABC, transporter
HPS43_21320	ENOG4105CSU	acyl-Coa dehydrogenase
HPS43_21325	ENOG4105CEY	Amp-dependent synthetase and ligase
HPS43_21345	ENOG4105DSQ	Nitric oxide reductase
HPS43_21365	ENOG4105MPD	Cytochrome
HPS43_21370	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
HPS43_21375	ENOG4105DC8	reductase
HPS43_21385	ENOG4105N14	lysine exporter protein LysE YggA
HPS43_21400	ENOG4108Q5Y	Membrane
HPS43_21420	ENOG4107QI1	Mate efflux family protein
HPS43_21425	ENOG4108IPT	Naphthoate synthase
HPS43_21430	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
HPS43_21440	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HPS43_21445	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
HPS43_21455	ENOG4105CHR	reductase
HPS43_21490	ENOG4108K3Z	AraC family transcriptional regulator
HPS43_21505	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
HPS43_21515	ENOG4108JQ1	Dehydrogenase
HPS43_21520	ENOG4105JSC	dimethylmenaquinone methyltransferase
HPS43_21530	ENOG4105DMF	Dehydrogenase
HPS43_21545	ENOG4105CNM	Receptor
HPS43_21550	ENOG4108S3W	Anti-feci sigma factor, fecr
HPS43_21555	ENOG4108SF5	RNA Polymerase
HPS43_21580	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
HPS43_21595	ENOG4105EUB	pirin domain protein
HPS43_21610	ENOG4105KWW	Biogenesis protein
HPS43_21615	ENOG4107QX9	Thiol disulfide interChange protein
HPS43_21620	ENOG4105DA4	cytochrome c-type biogenesis protein
HPS43_21625	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
HPS43_21635	ENOG41060IM	Heme exporter protein
HPS43_21640	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
HPS43_21645	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
HPS43_21665	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
HPS43_21670	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
HPS43_21675	ENOG4106WHD	Tetrathionate reductase
HPS43_21680	ENOG4105DB1	molybdopterin oxidoreductase
HPS43_21685	ENOG4108M1T	Cytochrome c-type biogenesis protein
HPS43_21690	ENOG4105KWW	Biogenesis protein
HPS43_21695	ENOG4107QX9	Thiol disulfide interChange protein
HPS43_21700	ENOG4105DA4	cytochrome c-type biogenesis protein
HPS43_21715	ENOG41060IM	Heme exporter protein
HPS43_21720	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
HPS43_21725	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
HPS43_21760	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HPS43_21765	ENOG4107RSM	transcriptional regulator
HPS43_21775	ENOG4105C01	Dihydroxy-acid dehydratase
HPS43_21785	ENOG4105BZU	Histidine kinase
HPS43_21790	ENOG4105E39	Enoyl-CoA hydratase
HPS43_21820	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HPS43_21830	ENOG4107S01	Repressor protein MetJ
HPS43_21840	ENOG4105CBN	LysR family transcriptional regulator
HPS43_21845	ENOG4105CY2	Citrate transporter
HPS43_21865	ENOG4105E09	nadh pyrophosphatase
HPS43_21885	ENOG4108S8N	class II Aldolase
HPS43_21890	ENOG4105CSH	Transporter
HPS43_21910	ENOG4105CEY	Amp-dependent synthetase and ligase
HPS43_21925	ENOG4105CHR	reductase
HPS43_21945	ENOG4105EW9	transcriptional regulator AsnC family
HPS43_21950	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
HPS43_21955	ENOG4108JJ7	ABC transporter
HPS43_21960	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HPS43_21965	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HPS43_21980	ENOG4105CEY	Amp-dependent synthetase and ligase
HPS43_21985	ENOG4105CHR	reductase
HPS43_22020	ENOG4105ETT	transcriptional Regulator, LysR family
HPS43_22030	ENOG4105F04	LysR family Transcriptional regulator
HPS43_22040	ENOG4105EJC	lysr family transcriptional regulator
HPS43_22055	ENOG4108IG5	Transcriptional regulator
HPS43_22065	ENOG4108I0C	methyltransferase
HPS43_22070	ENOG4105ETE	Transcriptional regulator (LacI family
HPS43_22075	ENOG4108SC4	)-transporter
HPS43_22080	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HPS43_22115	ENOG4105MEW	serine threonine protein phosphatase
HPS43_22135	ENOG4105CHR	reductase
HPS43_22145	ENOG4105C26	Dehydrogenase
HPS43_22150	ENOG4108R6K	riboflavin synthase, subunit alpha
HPS43_22160	ENOG4105CSP	Major Facilitator Superfamily
HPS43_22170	ENOG4108MK9	spermidine N(1)-acetyltransferase
HPS43_22180	ENOG4105W1Y	Transcriptional regulator
HPS43_22205	ENOG4105E0K	tonB-dependent siderophore receptor
HPS43_22210	ENOG4107R0V	Pyruvate dehydrogenase
HPS43_22215	ENOG4105CPP	Dehydrogenase, E1 component
HPS43_22220	ENOG4107QSN	dihydrolipoamide acetyltransferase
HPS43_22225	ENOG4107QN2	dihydrolipoyl dehydrogenase
HPS43_22235	ENOG4105CH7	arginosuccinase
HPS43_22240	ENOG4105CUY	Mechanosensitive ion channel
HPS43_22250	ENOG4108YZA	Nitrogen regulatory protein pii
HPS43_22255	ENOG4105D7Q	type ii secretion system
HPS43_22260	ENOG4105GVR	general secretion pathway protein D
HPS43_22265	ENOG4107QHF	type ii secretion system protein e
HPS43_22295	ENOG4108RTD	type II secretion system protein K
HPS43_22300	ENOG4108WWZ	General secretion pathway protein J
HPS43_22305	ENOG4105X5Z	General secretion pathway protein I
HPS43_22310	ENOG41069X0	general secretion pathway protein h
HPS43_22315	ENOG4108VAU	general secretion pathway protein G
HPS43_22335	ENOG4105HSS	phospholipase C
HPS43_22340	ENOG4105DUM	transcriptional regulator, lysR family
HPS43_22345	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HPS43_22350	ENOG4105DEF	Extracellular solute-binding protein, family 5
HPS43_22355	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HPS43_22360	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HPS43_22365	ENOG4108JQ6	ABC transporter
HPS43_22370	ENOG4108VWS	Yaeq family
HPS43_22385	ENOG4105C57	major facilitator superfamily
HPS43_22390	ENOG4105RUM	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
HPS43_22395	ENOG4105FE9	pseudouridine synthase
HPS43_22400	ENOG4105CR8	Transcriptional regulator
HPS43_22405	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HPS43_22410	ENOG4105BZS	acriflavin resistance protein
HPS43_22415	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HPS43_22435	ENOG4105DGW	oligopeptidase A
HPS43_22440	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
HPS43_22445	ENOG4108ZXC	Two component transcriptional regulator, luxr family
HPS43_22450	ENOG4105BZU	Histidine kinase
HPS43_22455	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
HPS43_22460	ENOG4107QSN	dihydrolipoamide acetyltransferase
HPS43_22465	ENOG4107QN2	dihydrolipoyl dehydrogenase
HPS43_22475	ENOG4105CBN	LysR family transcriptional regulator
HPS43_22490	ENOG4105I03	Flagellin
HPS43_22495	ENOG4106R49	Methyltransferase
HPS43_22500	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HPS43_22505	ENOG4105GEH	Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity)
HPS43_22510	ENOG4106CIA	Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region
HPS43_22515	ENOG4107RD7	Flagellar Motor Protein, MotA
HPS43_22520	ENOG4105ER2	Ompa motb domain protein
HPS43_22525	ENOG4108VYJ	response regulator receiver protein
HPS43_22535	ENOG4108V3W	Chemotaxis protein, CheW
HPS43_22540	ENOG4105C8Q	Methyl-accepting chemotaxis
HPS43_22545	ENOG4105BZU	Histidine kinase
HPS43_22550	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HPS43_22555	ENOG4108VYJ	response regulator receiver protein
HPS43_22560	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
HPS43_22565	ENOG4105C8Q	Methyl-accepting chemotaxis
HPS43_22570	ENOG4105D00	flagellar biosynthetic protein flhB
HPS43_22575	ENOG4105D7B	Flagellar biosynthesis protein flha
HPS43_22580	ENOG4105FZW	flagellar biosynthesis regulator FlhF
HPS43_22590	ENOG4105M9M	anti-sigma28 factor FlgM
HPS43_22600	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
HPS43_22605	ENOG4108ZC9	flagellar basal-body rod protein flgc
HPS43_22610	ENOG4105W00	Flagellar hook capping protein
HPS43_22615	ENOG4105BZE	flagellar hook protein, FlgE
HPS43_22620	ENOG4108KPB	Flagellar basal-body rod protein FlgF
HPS43_22625	ENOG4105CGA	flagellar basal-body rod protein FlgG
HPS43_22640	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
HPS43_22645	ENOG4105E1Q	flagellar hook-associated protein
HPS43_22650	ENOG4105DTJ	flagellar hook-associated protein
HPS43_22655	ENOG4105C8Q	Methyl-accepting chemotaxis
HPS43_22670	ENOG4105C8Q	Methyl-accepting chemotaxis
HPS43_22675	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
HPS43_22680	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
HPS43_22685	ENOG4105VS8	Flagellar biosynthetic protein fliq
HPS43_22690	ENOG4105CN7	Flagellar biosynthetic protein FliP
HPS43_22695	ENOG4105K0P	flagellar biosynthesis protein
HPS43_22700	ENOG4105DD5	Flagellar motor switch protein
HPS43_22705	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HPS43_22710	ENOG4107ZI8	flagellar basal body-associated protein flil
HPS43_22725	ENOG4108JIR	Flagellum-specific ATP synthase
HPS43_22735	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HPS43_22740	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
HPS43_22745	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
HPS43_22755	ENOG4105D00	flagellar biosynthetic protein flhB
HPS43_22770	ENOG4105MQ3	flagellar protein FliS
HPS43_22775	ENOG4105DTS	flagellar hook-associated
HPS43_22780	ENOG41063QE	flagellar protein FlaG
HPS43_22785	ENOG4106P37	HTH-type transcriptional regulator YjhI
HPS43_22795	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HPS43_22810	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HPS43_22825	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
HPS43_22830	ENOG4108VKG	metal-dependent hydrolase
HPS43_22835	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
HPS43_22845	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
HPS43_22850	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HPS43_22855	ENOG4105CE9	30S ribosomal protein S2
HPS43_22860	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
HPS43_22865	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
HPS43_22870	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
HPS43_22875	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HPS43_22880	ENOG4105KNE	Phosphatidate cytidylyltransferase
HPS43_22885	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
HPS43_22890	ENOG4105DZP	Membrane-associated zinc metalloprotease
HPS43_22895	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HPS43_22900	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
HPS43_22905	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HPS43_22910	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HPS43_22925	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HPS43_22945	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
HPS43_22950	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HPS43_22955	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HPS43_22975	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
HPS43_22980	ENOG4108Z1B	Cyclase dehydrase
HPS43_22995	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HPS43_23000	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HPS43_23015	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
HPS43_23020	ENOG4105HHA	aminodeoxychorismate lyase
HPS43_23025	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
HPS43_23030	ENOG4105C6E	dna polymerase iii
HPS43_23035	ENOG4105F8V	Hydrolase, tatD family
HPS43_23050	ENOG4106TNF	Periplasmic binding protein
HPS43_23055	ENOG4105E5Q	amino acid AbC transporter
HPS43_23060	ENOG4105CDA	abc transporter atp-binding protein
HPS43_23065	ENOG41088SP	formiminoglutamate hydrolase
HPS43_23075	ENOG4105D82	Glutamate dehydrogenase
HPS43_23085	ENOG4105DF9	Lipoate-protein, ligase
HPS43_23100	ENOG4105CYM	Glutathione S-transferase
HPS43_23110	ENOG4108YXU	transcriptional regulator AsnC family
HPS43_23115	ENOG4108V06	Glutathione peroxidase
HPS43_23120	ENOG4105F27	Major Facilitator
HPS43_23125	ENOG4105WAP	TPR repeat-containing protein
HPS43_23135	ENOG4107S2N	Type III effector Hrp-dependent
HPS43_23140	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
HPS43_23150	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
HPS43_23155	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
HPS43_23165	ENOG410846T	CoA-transferase family III
HPS43_23190	ENOG4108YZN	class I peptide chain release factor
HPS43_23200	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HPS43_23230	ENOG4108KXH	Ybak prolyl-tRNA synthetase associated
HPS43_23245	ENOG4107QWP	ABC-2 type transporter
HPS43_23250	ENOG4105CJ1	ABC, transporter
HPS43_23260	ENOG410630P	Transcriptional regulator
HPS43_23265	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
HPS43_23275	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HPS43_23285	ENOG4105E98	transcriptional regulator DeoR family
HPS43_23290	ENOG4108IJ9	(ABC) transporter
HPS43_23295	ENOG4108IJ9	(ABC) transporter
HPS43_23345	ENOG41090KQ	Glyoxalase Bleomycin resistance protein (Dioxygenase
HPS43_23350	ENOG4108Z9W	Outer membrane porin
HPS43_23370	ENOG4108JU3	Alkyl hydroperoxide reductase
HPS43_23375	ENOG4108Z40	Transcriptional regulator
HPS43_23380	ENOG4105C1G	acyl-Coa dehydrogenase
HPS43_23410	ENOG4105EW9	transcriptional regulator AsnC family
HPS43_23415	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
HPS43_23420	ENOG4107RH8	nuclease SbcCD subunit D
HPS43_23455	ENOG4108ZE9	Monovalent cation H antiporter subunit C
HPS43_23460	ENOG4107R4Z	monovalent cation h antiporter subunit d
HPS43_23465	ENOG4105SC1	monovalent cation H antiporter subunit E
HPS43_23470	ENOG4105W4C	monovalent cation H antiporter subunit F
HPS43_23475	ENOG4105KJM	monovalent cation h antiporter subunit g
HPS43_23485	ENOG4106TCE	
HPS43_23490	ENOG4108Z6B	deaminase
HPS43_23495	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
HPS43_23500	ENOG4105C5H	ABC transporter
HPS43_23535	ENOG41080RH	Thioredoxin
HPS43_23540	ENOG4105DEN	Luciferase family
HPS43_23550	ENOG4105C7N	Xanthine uracil vitamin C permease
HPS43_23555	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HPS43_23560	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
HPS43_23570	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
HPS43_23575	ENOG4108K5P	(LipO)protein
HPS43_23595	ENOG4106NZI	LysR family Transcriptional regulator
HPS43_23600	ENOG4105F27	Major Facilitator
HPS43_23605	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
HPS43_23625	ENOG4105EHV	domain protein
HPS43_23635	ENOG4105D6S	protein involved in catabolism of external DNA
HPS43_23640	ENOG4107T6V	glycerophosphoryl diester phosphodiesterase
HPS43_23650	ENOG4105EIN	peptidylprolyl cis-trans isomerase
HPS43_23655	ENOG4108UJV	acyl-CoA thioesterase i
HPS43_23660	ENOG4108I0Y	(ABC) transporter
HPS43_23670	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
HPS43_23675	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HPS43_23680	ENOG4105ETT	transcriptional Regulator, LysR family
HPS43_23685	ENOG4105EAC	phosphoserine phosphatase
HPS43_23700	ENOG4105DND	Transcriptional regulator
HPS43_23715	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HPS43_23730	ENOG4105DND	Transcriptional regulator
HPS43_23735	ENOG4105CFM	UPF0317 protein
HPS43_23745	ENOG4105C32	Amino acid ABC transporter (Permease)
HPS43_23755	ENOG4105C0Z	ABC transporter
HPS43_23760	ENOG4108IV0	ABC, transporter
HPS43_23765	ENOG4108Z9W	Outer membrane porin
HPS43_23770	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HPS43_23785	ENOG4105E09	nadh pyrophosphatase
HPS43_23825	ENOG4107R0W	ABC transporter
HPS43_23830	ENOG4105E5Q	amino acid AbC transporter
HPS43_23835	ENOG4105CDA	abc transporter atp-binding protein
HPS43_23840	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HPS43_23845	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
HPS43_23850	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
HPS43_23865	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HPS43_23875	ENOG4105D5K	Hemolysin activator protein
HPS43_23880	ENOG4105CKT	filamentous hemagglutinin
HPS43_23890	ENOG4105K4H	Nlp p60 protein
HPS43_23895	ENOG4105UGU	tonB-dependent Receptor
HPS43_23905	ENOG4105FYV	Amp nucleosidase
HPS43_23910	ENOG4108IQI	permease
HPS43_23915	ENOG4105DSJ	YicC domain protein
HPS43_23920	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
HPS43_23930	ENOG4105C1G	acyl-Coa dehydrogenase
HPS43_23940	ENOG4105BZU	Histidine kinase
HPS43_23945	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HPS43_23950	ENOG4105CSA	Coproporphyrinogen iii oxidase
HPS43_23960	ENOG4105CUX	Signal transduction histidine kinase
HPS43_23965	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HPS43_23970	ENOG4105EQ1	Transcriptional regulator
HPS43_23980	ENOG4105EUB	pirin domain protein
HPS43_23990	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HPS43_23995	ENOG4105E0C	molybdate abc transporter
HPS43_24005	ENOG4105DP0	ferredoxin-NADP reductase
HPS43_24025	ENOG4105DND	Transcriptional regulator
HPS43_24030	ENOG4105KME	endoribonuclease L-psp
HPS43_24035	ENOG4105CB5	ATP-dependent DNA helicase recG
HPS43_24055	ENOG4106EYY	
HPS43_24060	ENOG4107TAE	Glycosyl transferase (Group 1
HPS43_24085	ENOG4106PQC	
HPS43_24090	ENOG4105DBA	pectate lyase
HPS43_24100	ENOG4105CP9	extracellular ligand-binding receptor
HPS43_24105	ENOG4107EXC	regulatoR
HPS43_24110	ENOG4105JJR	Histidine kinase
HPS43_24125	ENOG4108IJ9	(ABC) transporter
HPS43_24135	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
HPS43_24140	ENOG4105BZ7	extracellular solute-binding protein family 1
HPS43_24145	ENOG4105II7	pyrroline-5-carboxylate reductase
HPS43_24150	ENOG4105EX9	Membrane
HPS43_24160	ENOG4105CP9	extracellular ligand-binding receptor
HPS43_24165	ENOG4105C32	Amino acid ABC transporter (Permease)
HPS43_24170	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
HPS43_24175	ENOG4105C0Z	ABC transporter
HPS43_24180	ENOG4108IV0	ABC, transporter
HPS43_24205	ENOG4105RQF	LysR family Transcriptional regulator
HPS43_24210	ENOG4108K3A	Glutathione S-transferase
HPS43_24215	ENOG4105D8V	Glucose sorbosone dehydrogenase
HPS43_24225	ENOG4105DJP	Membrane
HPS43_24250	ENOG4105CYW	agmatinase
HPS43_24260	ENOG4105D01	(LipO)protein
HPS43_24270	ENOG4107SHS	Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites (By similarity)
HPS43_24280	ENOG4107RN3	metallophosphoesterase
HPS43_24290	ENOG4105DJ4	phosphatidylserine decarboxylase
HPS43_24295	ENOG4105C5H	ABC transporter
HPS43_24320	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
HPS43_24325	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HPS43_24330	ENOG4105BZU	Histidine kinase
HPS43_24345	ENOG4105D94	Major Facilitator Superfamily
HPS43_24350	ENOG4105GEH	Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity)
HPS43_24360	ENOG4105EYM	Major Facilitator superfamily
HPS43_24385	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HPS43_24390	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HPS43_24395	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HPS43_24445	ENOG4107R7Y	intracellular protease Pfpi family
HPS43_24465	ENOG4105C5I	Dehydrogenase
HPS43_24480	ENOG4105BZU	Histidine kinase
HPS43_24515	ENOG4106RE7	Cytochrome
HPS43_24530	ENOG4105EE5	Membrane protein terC
HPS43_24545	ENOG4105JJR	Histidine kinase
HPS43_24580	ENOG4108VAU	general secretion pathway protein G
HPS43_24605	ENOG4107QHF	type ii secretion system protein e
HPS43_24610	ENOG4105D7Q	type ii secretion system
HPS43_24615	ENOG4108UPW	ABC transporter
HPS43_24665	ENOG4105X5Z	General secretion pathway protein I
HPS43_24705	ENOG4105BZU	Histidine kinase
HPS43_24710	ENOG4108Z4X	TRANSCRIPTIONal
HPS43_24720	ENOG4105BZU	Histidine kinase
HPS43_24750	ENOG4108IY8	ABC, transporter
HPS43_24755	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
HPS43_24760	ENOG4106FTQ	Taurine ABC transporter, periplasmic
HPS43_24785	ENOG4105CN1	protease
HPS43_24805	ENOG4105IPI	Membrane
HPS43_24815	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
HPS43_24875	ENOG4105KME	endoribonuclease L-psp
HPS43_24880	ENOG4105FC8	fad dependent oxidoreductase
HPS43_24895	ENOG4105ERH	Fumarylacetoacetate hydrolase
HPS43_24925	ENOG4108DNI	pyridine nucleotide-disulfide oxidoreductase
HPS43_24965	ENOG4108K3A	Glutathione S-transferase
HPS43_24970	ENOG4105DUM	transcriptional regulator, lysR family
HPS43_24980	ENOG4105CSH	Transporter
HPS43_24990	ENOG4105DWT	malate dehydrogenase (quinone)
HPS43_25030	ENOG4105D6J	arsenicaL-resistance protein
HPS43_25040	ENOG41085FC	arsR family transcriptional regulator
HPS43_25050	ENOG4105D8X	mechanosensitive ion channel
HPS43_25065	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HPS43_25070	ENOG4105BZS	acriflavin resistance protein
HPS43_25075	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HPS43_25095	ENOG4107RSM	transcriptional regulator
HPS43_25100	ENOG4105DZ0	fad dependent oxidoreductase
HPS43_25120	ENOG4105CDA	abc transporter atp-binding protein
HPS43_25125	ENOG4105DRP	amino acid AbC transporter
HPS43_25130	ENOG4105EZ7	amino acid ABC transporter
HPS43_25135	ENOG4107QXX	ABC transporter
HPS43_25140	ENOG4105C28	cystathionine
HPS43_25145	ENOG4105RQF	LysR family Transcriptional regulator
HPS43_25165	ENOG4105C3U	ABC transporter
HPS43_25170	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HPS43_25175	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HPS43_25180	ENOG4105DEF	Extracellular solute-binding protein, family 5
HPS43_25190	ENOG4105RQF	LysR family Transcriptional regulator
HPS43_25195	ENOG4105CHJ	isochorismatase hydrolase
HPS43_25200	ENOG41088CQ	domain protein
HPS43_25210	ENOG4105H1G	trap transporter solute receptor taxi family
HPS43_25215	ENOG4105DG7	nitrate ABC transporter
HPS43_25220	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
HPS43_25225	ENOG4105D7T	ABC transporter
HPS43_25235	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HPS43_25245	ENOG4108PG2	copper resistance
HPS43_25275	ENOG4105CTX	dehydratase
HPS43_25295	ENOG4105ETX	regulatoR
HPS43_25305	ENOG4105EHG	Permease protein
HPS43_25310	ENOG41090JD	Blue (Type 1) copper domain protein
HPS43_25315	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HPS43_25320	ENOG4105C7B	Threonine dehydratase
HPS43_25325	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
HPS43_25330	ENOG4105E9K	Isocitrate dehydrogenase
HPS43_25335	ENOG4105DQR	SNARE associated Golgi
HPS43_25345	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HPS43_25350	ENOG4105F1Y	L-lysine 6-monooxygenase (NADPH)
HPS43_25385	ENOG4105CNM	Receptor
HPS43_25395	ENOG4105DQ5	transport system permease protein
HPS43_25400	ENOG4105TVJ	transport system, permease
HPS43_25405	ENOG4105E0A	ABC, transporter
HPS43_25410	ENOG4105CDA	abc transporter atp-binding protein
HPS43_25415	ENOG4105E5Q	amino acid AbC transporter
HPS43_25420	ENOG4105EAB	amino acid AbC transporter
HPS43_25425	ENOG4105EA8	2-Nitropropane dioxygenase
HPS43_25430	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HPS43_25440	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HPS43_25450	ENOG4105CEY	Amp-dependent synthetase and ligase
HPS43_25465	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
HPS43_25470	ENOG4108KXM	LysR family Transcriptional regulator
HPS43_25475	ENOG4105CMQ	Chloride channel
HPS43_25480	ENOG41067TZ	transcriptional regulator, MarR family
HPS43_25490	ENOG4105BZU	Histidine kinase
HPS43_25495	ENOG4108ZXC	Two component transcriptional regulator, luxr family
HPS43_25530	ENOG4107R11	Transcriptional regulator
HPS43_25550	ENOG4105CDA	abc transporter atp-binding protein
HPS43_25560	ENOG4105E5Q	amino acid AbC transporter
HPS43_25615	ENOG4108UQ8	endoribonuclease L-psp
HPS43_25650	ENOG4108KB2	LysR family Transcriptional regulator
HPS43_25655	ENOG4105DTQ	mandelate racemase muconate lactonizing
HPS43_25665	ENOG4105DRR	Transcriptional regulator, GntR family
HPS43_25670	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HPS43_25685	ENOG4105JSC	dimethylmenaquinone methyltransferase
HPS43_25710	ENOG4105DG7	nitrate ABC transporter
HPS43_25715	ENOG4105I5W	Transporter
HPS43_25720	ENOG4105D7T	ABC transporter
HPS43_25735	ENOG41063TF	transcriptional regulator (AraC
HPS43_25760	ENOG4105EZ7	amino acid ABC transporter
HPS43_25780	ENOG4105WH1	Two component transcriptional regulator luxr family
HPS43_25785	ENOG4105BZU	Histidine kinase
HPS43_25790	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
HPS43_25795	ENOG4107B2H	carbonic anhydrase
HPS43_25800	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HPS43_25805	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
HPS43_25810	ENOG41076YT	nitrate reductase, gamma subunit
HPS43_25815	ENOG4105R3A	Nitrate reductase
HPS43_25820	ENOG4108IUE	nitrate reductase beta subunit
HPS43_25830	ENOG4105DQQ	Major facilitator superfamily MFS_1
HPS43_25855	ENOG4105HEI	LysR family (Transcriptional regulator
HPS43_25865	ENOG4105BZS	acriflavin resistance protein
HPS43_25870	ENOG4105BZS	acriflavin resistance protein
HPS43_25875	ENOG4105EMY	transcriptional regulator
HPS43_25915	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HPS43_25935	ENOG4105EA8	2-Nitropropane dioxygenase
HPS43_25950	ENOG4105BZU	Histidine kinase
HPS43_25955	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HPS43_25960	ENOG4108S1C	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
HPS43_25965	ENOG4105EQW	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
HPS43_25975	ENOG4105E0X	reductase
HPS43_25980	ENOG4107U7B	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HPS43_26025	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HPS43_26030	ENOG4105T38	integral membrane protein
HPS43_26035	ENOG4105VCD	cytoplasmic protein
HPS43_26040	ENOG4105D22	carbon starvation protein
HPS43_26055	ENOG4105EUJ	GTP cyclohydrolase i
HPS43_26065	ENOG4107NQ8	LysR family Transcriptional regulator
HPS43_26070	ENOG4106FTQ	Taurine ABC transporter, periplasmic
HPS43_26080	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
HPS43_26085	ENOG4105DFG	type I secretion outer membrane protein
HPS43_26095	ENOG4108JJA	ABC, transporter
HPS43_26115	ENOG4108S3W	Anti-feci sigma factor, fecr
HPS43_26120	ENOG4108SF5	RNA Polymerase
HPS43_26125	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HPS43_26135	ENOG4108S8N	class II Aldolase
HPS43_26140	ENOG4105CJP	fad dependent oxidoreductase
HPS43_26150	ENOG4105CKI	cobalamin synthesis protein
HPS43_26155	ENOG4105CI2	imidazolone-5-propionate hydrolase
HPS43_26160	ENOG4108JQ6	ABC transporter
HPS43_26165	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HPS43_26170	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HPS43_26175	ENOG4108HIY	periplasmic
HPS43_26190	ENOG4108FUF	Transcriptional regulator, IclR family
HPS43_26195	ENOG4105C1J	atp-dependent rna helicase
HPS43_26200	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
HPS43_26215	ENOG4105DSW	Fusaric acid resistance protein
HPS43_26220	ENOG4105ZQC	membrane protein AaeX
HPS43_26225	ENOG4105Y49	secretion protein, HlyD family
HPS43_26240	ENOG4105C7K	acetolactate synthase
HPS43_26250	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
HPS43_26260	ENOG4106KED	esterase YpfH
HPS43_26265	ENOG4108IQI	permease
HPS43_26270	ENOG4105C8Q	Methyl-accepting chemotaxis
HPS43_26285	ENOG4105C0B	DNA polymerase III (alpha subunit)
HPS43_26300	ENOG4105EQ2	LysR family Transcriptional regulator
HPS43_26305	ENOG4107S5I	aldo keto reductase
HPS43_26315	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HPS43_26380	ENOG4108VKM	cytochrome b561
HPS43_26405	ENOG4105C8Q	Methyl-accepting chemotaxis
HPS43_26440	ENOG4108X7C	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
HPS43_26455	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
HPS43_26460	ENOG4108IUZ	ABC transporter
HPS43_26465	ENOG4105C0Z	ABC transporter
HPS43_26470	ENOG4105C32	Amino acid ABC transporter (Permease)
HPS43_26485	ENOG4108SQ4	Glyoxalase Bleomycin resistance protein (Dioxygenase
HPS43_26505	ENOG4105E0K	tonB-dependent siderophore receptor
HPS43_26520	ENOG4108FUF	Transcriptional regulator, IclR family
HPS43_26535	ENOG4105CPC	Aldo Keto reductase
HPS43_26550	ENOG4105PF9	Transcriptional regulator
HPS43_26570	ENOG4105EWC	Purine nucleoside phosphorylase
HPS43_26580	ENOG4105R1U	AraC Family Transcriptional Regulator
HPS43_26595	ENOG4107R0U	MotA TolQ exbB proton channel
HPS43_26615	ENOG4105GRZ	Ycii-related protein
HPS43_26620	ENOG4105GRZ	Ycii-related protein
HPS43_26630	ENOG4105CHP	RNA polymerase
HPS43_26640	ENOG4105DXC	membrane
HPS43_26650	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
HPS43_26660	ENOG4105DUM	transcriptional regulator, lysR family
HPS43_26680	ENOG4108K3A	Glutathione S-transferase
HPS43_26690	ENOG41082F9	transcriptional regulator
HPS43_26695	ENOG410756H	nucleotidyltransferase
HPS43_26715	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HPS43_26765	ENOG4105ER2	Ompa motb domain protein
HPS43_26825	ENOG4105CS6	Rhs element vgr protein
HPS43_26830	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HPS43_26885	ENOG4105CS6	Rhs element vgr protein
HPS43_26970	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HPS43_26980	ENOG4108TGY	Glutathione S-transferase
HPS43_26985	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HPS43_26990	ENOG4106BRA	Membrane
HPS43_27000	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HPS43_27025	ENOG4105CBN	LysR family transcriptional regulator
HPS43_27030	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HPS43_27035	ENOG4105CHU	acetyl-coa acetyltransferase
HPS43_27040	ENOG4105CC9	acyl-Coa dehydrogenase
HPS43_27045	ENOG4105C1G	acyl-Coa dehydrogenase
HPS43_27050	ENOG4105CEY	Amp-dependent synthetase and ligase
HPS43_27055	ENOG4105JN3	extra-cytoplasmic solute receptor family protein
HPS43_27060	ENOG4105K6H	D-cysteine desulfhydrase
HPS43_27075	ENOG4105F04	LysR family Transcriptional regulator
HPS43_27085	ENOG4108VHT	MarR family transcriptional regulator
HPS43_27090	ENOG41079KZ	Major Facilitator Superfamily
HPS43_27095	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
HPS43_27100	ENOG4108XHQ	(2Fe-2S)-binding domain protein
HPS43_27120	ENOG4108UAU	isochorismatase
HPS43_27125	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
HPS43_27135	ENOG4105F7P	transcriptional regulator AsnC family
HPS43_27140	ENOG4108Z9W	Outer membrane porin
HPS43_27145	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HPS43_27150	ENOG4105C4Y	ABC transporter
HPS43_27155	ENOG4105E0C	molybdate abc transporter
HPS43_27165	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HPS43_27170	ENOG4105CBS	Chea signal transduction histidine kinase
HPS43_27180	ENOG4108KTQ	Methyltransferase
HPS43_27190	ENOG4105C8Q	Methyl-accepting chemotaxis
HPS43_27195	ENOG4105DV0	amidase (EC 3.5.1.4
HPS43_27210	ENOG4105CC0	LysR family Transcriptional regulator
HPS43_27230	ENOG4105F2V	VRR-NUC domain-containing protein
HPS43_27240	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
HPS43_27255	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
HPS43_27325	ENOG4106IQC	argininosuccinate lyase
HPS43_27340	ENOG4105EJC	lysr family transcriptional regulator
HPS43_27345	ENOG4108Z6Z	Transcriptional regulator
HPS43_27355	ENOG4105JJR	Histidine kinase
HPS43_27365	ENOG4105D74	hydrolase
HPS43_27375	ENOG4105EMU	Dehydrogenase
HPS43_27380	ENOG4105CF7	AraC family transcriptional regulator
HPS43_27410	ENOG4105MHT	Transcriptional regulator, ARSR family
HPS43_27415	ENOG4105WAB	arsR family transcriptional regulator
HPS43_27425	ENOG4105DAE	Methylenetetrahydrofolate reductase
HPS43_27430	ENOG4105DZ2	Transcriptional regulator
HPS43_27435	ENOG4108UZX	fmn reductase
HPS43_27490	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HPS43_27495	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HPS43_27515	ENOG4107RSM	transcriptional regulator
HPS43_27525	ENOG4105C5I	Dehydrogenase
HPS43_27550	ENOG4105EMY	transcriptional regulator
HPS43_27560	ENOG4105DV0	amidase (EC 3.5.1.4
HPS43_27575	ENOG4107X2D	transcriptional regulator, merr family
HPS43_27585	ENOG4105E1J	oxidoreductase
HPS43_27590	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HPS43_27595	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HPS43_27600	ENOG4105C3U	ABC transporter
HPS43_27605	ENOG4108JQ7	(ABC) transporter
HPS43_27610	ENOG4105DEF	Extracellular solute-binding protein, family 5
HPS43_27655	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
HPS43_27675	ENOG4105CI0	Citrate lyase
HPS43_27680	ENOG4105DND	Transcriptional regulator
HPS43_27700	ENOG4105CNM	Receptor
HPS43_27735	ENOG4108K0B	C-di-gmp phosphodiesterase
HPS43_27740	ENOG4105E0K	tonB-dependent siderophore receptor
HPS43_27755	ENOG4105CBN	LysR family transcriptional regulator
HPS43_27780	ENOG4105ZRN	
HPS43_27795	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HPS43_27805	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
HPS43_27825	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
HPS43_27840	ENOG4105CC0	LysR family Transcriptional regulator
HPS43_27845	ENOG4105BZU	Histidine kinase
HPS43_27880	ENOG4107YNJ	LysR family Transcriptional regulator
HPS43_27885	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HPS43_27895	ENOG4105DTD	Dehydrogenase
HPS43_27905	ENOG41082CG	Protein CrcB homolog
HPS43_27920	ENOG4107YNJ	LysR family Transcriptional regulator
HPS43_27945	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HPS43_27960	ENOG4105C8Q	Methyl-accepting chemotaxis
HPS43_27965	ENOG4108SF5	RNA Polymerase
HPS43_27970	ENOG4108S3W	Anti-feci sigma factor, fecr
HPS43_27975	ENOG4105E0K	tonB-dependent siderophore receptor
HPS43_27980	ENOG4108ETH	Formylglycinamide ribotide synthetase
HPS43_27990	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HPS43_27995	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HPS43_28030	ENOG4108RRZ	Transcription elongation factor GreB
HPS43_28035	ENOG4105DB7	PHP domain protein
HPS43_28050	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HPS43_28060	ENOG4105DND	Transcriptional regulator
HPS43_28070	ENOG4105DUM	transcriptional regulator, lysR family
HPS43_28075	ENOG4105CSH	Transporter
HPS43_28080	ENOG4107S4Y	M20 DapE family protein YgeY
HPS43_28085	ENOG4108EC8	DNA internalization-related competence protein ComEC
HPS43_28090	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
HPS43_28100	ENOG4108MGI	Transcriptional regulator
HPS43_28115	ENOG4105CXG	d-lactate dehydrogenase
HPS43_28165	ENOG4105VG5	Membrane
HPS43_28170	ENOG4105JP4	Inner membrane protein yidG
HPS43_28175	ENOG41082AG	Plasmid maintenance system antidote protein
HPS43_28200	ENOG4108X0B	nad(p)h dehydrogenase (quinone)
HPS43_28210	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
HPS43_28215	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
HPS43_28250	ENOG4105E6M	Sulphatase-modifying factor protein
HPS43_28255	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HPS43_28290	ENOG4105ENH	Sulfatase
HPS43_28300	ENOG4105N14	lysine exporter protein LysE YggA
HPS43_28330	ENOG4108ZIT	Ferredoxin, 2FE-2S
HPS43_28335	ENOG4105DTD	Dehydrogenase
HPS43_28340	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HPS43_28350	ENOG4107XC4	flavin reductase domain protein, FMN-binding
HPS43_28380	ENOG4105E0K	tonB-dependent siderophore receptor
HPS43_28385	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
HPS43_28390	ENOG4108IPW	abc transporter atp-binding protein
HPS43_28395	ENOG4105CM4	permease protein
HPS43_28400	ENOG4105DHS	permease protein
HPS43_28410	ENOG4105D05	Receptor
HPS43_28415	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HPS43_28420	ENOG410804D	Sensor Signal Transduction Histidine Kinase
HPS43_28425	ENOG4105F8V	Hydrolase, tatD family
HPS43_28430	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HPS43_28445	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HPS43_28450	ENOG4105CSP	Major Facilitator Superfamily
HPS43_28460	ENOG410904N	short-chain dehydrogenase reductase
HPS43_28465	ENOG4105CRK	lysyL-tRNA synthetase
HPS43_28480	ENOG4105DKK	Benzoate
HPS43_28485	ENOG4105DFA	alanine racemase domain protein
HPS43_28490	ENOG4108RZE	Tetr family transcriptional regulator
HPS43_28495	ENOG4105CHU	acetyl-coa acetyltransferase
HPS43_28500	ENOG4108IQE	Amp-dependent synthetase and ligase
HPS43_28505	ENOG4108IV0	ABC, transporter
HPS43_28525	ENOG4105C0Z	ABC transporter
HPS43_28530	ENOG4105CGU	Enoyl-CoA hydratase
HPS43_28540	ENOG4108Z5K	methylglyoxal synthase
HPS43_28545	ENOG4105WVQ	Fe-S assembly protein IscX
HPS43_28550	ENOG4108ZIT	Ferredoxin, 2FE-2S
HPS43_28555	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
HPS43_28560	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
HPS43_28565	ENOG4108Z4V	iron-sulfur cluster assembly
HPS43_28570	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
HPS43_28575	ENOG4105C3J	Cysteine desulfurase
HPS43_28590	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HPS43_28595	ENOG4105CGF	Aromatic amino acid aminotransferase
HPS43_28600	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HPS43_28605	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HPS43_28610	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HPS43_28615	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HPS43_28620	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
HPS43_28625	ENOG4108K0D	peptidase, M48
HPS43_28630	ENOG4108TEB	UPF0114 protein
HPS43_28635	ENOG4105VEQ	Cold shock protein
HPS43_28645	ENOG4105VEQ	Cold shock protein
HPS43_28670	ENOG4105KME	endoribonuclease L-psp
HPS43_28680	ENOG4105EJC	lysr family transcriptional regulator
HPS43_28695	ENOG4108IG5	Transcriptional regulator
HPS43_28715	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
HPS43_28905	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HPS43_28920	ENOG4105UZW	Tail fiber assembly protein
HPS43_29070	ENOG4105FA0	parb-like partition protein
HPS43_29135	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
HPS43_29145	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
HPS43_29150	ENOG4105C5H	ABC transporter
HPS43_29165	ENOG4105PE1	Receptor
HPS43_29170	ENOG4105PE1	Receptor
HPS43_29175	ENOG4105PE1	Receptor
HPS43_29195	ENOG4105C4R	Atp-dependent dna helicase
HPS43_29215	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HPS43_29220	ENOG4105DTN	riboflavin biosynthesis protein ribF
HPS43_29225	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HPS43_29230	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HPS43_29235	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
HPS43_29255	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
HPS43_29285	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HPS43_29315	ENOG4105CIF	Ornithine Cyclodeaminase
HPS43_29320	ENOG4108Z9K	Osmotically inducible protein
HPS43_29325	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
HPS43_29330	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
HPS43_29335	ENOG4105CYM	Glutathione S-transferase
HPS43_29345	ENOG4105CQ0	ABC transporter
HPS43_29355	ENOG4107ENK	receptor
HPS43_29370	ENOG4105DCM	major facilitator superfamily
HPS43_29375	ENOG4108IV0	ABC, transporter
HPS43_29380	ENOG4105C0Z	ABC transporter
HPS43_29385	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
HPS43_29390	ENOG4105C32	Amino acid ABC transporter (Permease)
HPS43_29400	ENOG4105C26	Dehydrogenase
HPS43_29410	ENOG4105DY2	Paraquat-inducible protein b
HPS43_29415	ENOG4105F1S	paraquat-inducible protein a
HPS43_29425	ENOG4108JQB	penicillin-binding protein 1C
HPS43_29430	ENOG4105DN3	alpha-2-macroglobulin domain protein
HPS43_29435	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
HPS43_29440	ENOG4105VEQ	Cold shock protein
HPS43_29450	ENOG4105CHU	acetyl-coa acetyltransferase
HPS43_29455	ENOG4105CMQ	Chloride channel
HPS43_29460	ENOG4105C8Q	Methyl-accepting chemotaxis
HPS43_29465	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HPS43_29475	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HPS43_29490	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
HPS43_29500	ENOG4105W49	UPF0434 protein
HPS43_29505	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
HPS43_29520	ENOG4105CJR	Integral membrane protein (MviN
HPS43_29530	ENOG41082GY	Binds directly to 16S ribosomal RNA (By similarity)
HPS43_29535	ENOG4105RQF	LysR family Transcriptional regulator
HPS43_29545	ENOG4105CNV	Aldolase
HPS43_29555	ENOG4105DG4	malate L-lactate dehydrogenase
HPS43_29560	ENOG4107YCY	Transcriptional regulator
HPS43_29580	ENOG4105C5I	Dehydrogenase
HPS43_29595	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
HPS43_29610	ENOG4107THI	3,4-dihydroxyphenylacetate 2,3-dioxygenase
HPS43_29615	ENOG4105C26	Dehydrogenase
HPS43_29640	ENOG4105CHR	reductase
HPS43_29645	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HPS43_29665	ENOG4108ARY	Protein CrcB homolog
HPS43_29690	ENOG4105CJ2	(LipO)protein
HPS43_29725	ENOG4105EQN	UPF0261 protein
HPS43_29750	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HPS43_29760	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
HPS43_29770	ENOG4105CSH	Transporter
HPS43_29790	ENOG4108YZ4	nudix hydrolase
HPS43_29795	ENOG4105CR8	Transcriptional regulator
HPS43_29800	ENOG4105R8A	Heat shock protein
HPS43_29815	ENOG4105CNM	Receptor
HPS43_29820	ENOG4105CNM	Receptor
HPS43_29825	ENOG4105WPR	Transcriptional regulator, ARAC family
HPS43_29835	ENOG4105DXI	Major Facilitator superfamily
HPS43_29845	ENOG4105VRT	cytoplasmic protein
HPS43_29860	ENOG4108TGY	Glutathione S-transferase
HPS43_29880	ENOG4105GAK	amidohydrolase 2
HPS43_29895	ENOG4108JQ1	Dehydrogenase
HPS43_29955	ENOG4108XM1	transcriptional regulator AsnC family
HPS43_29980	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HPS43_29990	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HPS43_30010	ENOG4108SF5	RNA Polymerase
HPS43_30030	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HPS43_30040	ENOG4105CVE	Lytic murein transglycosylase
HPS43_30050	ENOG4105DDW	LysR family Transcriptional regulator
HPS43_30060	ENOG4105EBR	Carboxylesterase
HPS43_30080	ENOG4105CH2	amidohydrolase
HPS43_30090	ENOG4108Q27	Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate (By similarity)
HPS43_30105	ENOG4105GAK	amidohydrolase 2
HPS43_30115	ENOG4105BZU	Histidine kinase
HPS43_30120	ENOG4105VEJ	Heat shock protein
HPS43_30125	ENOG4105CSR	polyphosphate kinase 2
HPS43_30145	ENOG4108UMI	ABC transporter, permease
HPS43_30150	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HPS43_30155	ENOG4105D01	(LipO)protein
HPS43_30165	ENOG4105DNH	Major Facilitator
HPS43_30175	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
HPS43_30180	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HPS43_30200	ENOG4105JAB	phenazine biosynthesis protein, phzf family
HPS43_30210	ENOG4108EX3	reductase
HPS43_30220	ENOG4105EZR	dyp-type peroxidase family protein
HPS43_30230	ENOG4105CBN	LysR family transcriptional regulator
HPS43_30235	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HPS43_30270	ENOG4108UT2	hemolysin iii
HPS43_30280	ENOG4105VEQ	Cold shock protein
HPS43_30310	ENOG4105DVW	rieske (2Fe-2S)
HPS43_30325	ENOG4108JA1	polyketide synthase
HPS43_30335	ENOG4105CEY	Amp-dependent synthetase and ligase
HPS43_30340	ENOG4108NDG	TRAP dicarboxylate
HPS43_30350	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HPS43_30355	ENOG4108ZXC	Two component transcriptional regulator, luxr family
HPS43_30365	ENOG4105CHU	acetyl-coa acetyltransferase
HPS43_30380	ENOG4105E3A	(ABC) transporter
HPS43_30385	ENOG4105DA5	(ABC) transporter
HPS43_30405	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
HPS43_30430	ENOG4105SG9	biopolymer transport protein, ExbD
HPS43_30435	ENOG4105E02	MotA TolQ exbB proton channel