locus-tag	class	description
Axylo_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Axylo_0002	COG0592	DNA-directed DNA polymerase activity
Axylo_0004	COG0583	DNA-binding transcription factor activity
Axylo_0009	COG1574	metal-dependent hydrolase with the TIM-barrel fold
Axylo_0011	COG0583	DNA-binding transcription factor activity
Axylo_0012	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Axylo_0013	COG0765	amino acid transport
Axylo_0014	COG0765	amino acid transport
Axylo_0015	COG1126	abc transporter atp-binding protein
Axylo_0018	COG1254	Belongs to the acylphosphatase family
Axylo_0020	COG1304	FMN binding
Axylo_0022	COG3842	ATPase activity
Axylo_0023	COG1176	ABC-type spermidine putrescine transport system, permease component I
Axylo_0024	COG1177	transmembrane transport
Axylo_0027	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Axylo_0035	COG1609	Transcriptional regulator
Axylo_0037	COG3842	ATPase activity
Axylo_0038	COG1176	ABC-type spermidine putrescine transport system, permease component I
Axylo_0039	COG1177	transmembrane transport
Axylo_0044	COG0251	oxidation-reduction process
Axylo_0046	COG3210	domain, Protein
Axylo_0049	COG0402	S-adenosylhomocysteine deaminase activity
Axylo_0053	COG1744	ABC transporter substrate-binding protein PnrA-like
Axylo_0055	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
Axylo_0058	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Axylo_0063	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Axylo_0065	COG3781	membrane
Axylo_0066	COG1522	sequence-specific DNA binding
Axylo_0067	COG0028	Belongs to the TPP enzyme family
Axylo_0068	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_0069	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Axylo_0070	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
Axylo_0074	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Axylo_0075	COG2922	Belongs to the Smg family
Axylo_0081	COG0765	amino acid transport
Axylo_0082	COG0765	amino acid transport
Axylo_0083	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Axylo_0084	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_0085	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Axylo_0089	COG4977	sequence-specific DNA binding
Axylo_0090	COG2814	Major facilitator Superfamily
Axylo_0093	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
Axylo_0095	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
Axylo_0099	COG3339	Conserved Protein
Axylo_0101	COG1280	lysine exporter protein (LysE YggA)
Axylo_0109	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Axylo_0110	COG0183	Belongs to the thiolase family
Axylo_0111	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
Axylo_0112	COG1960	acyl-CoA dehydrogenase activity
Axylo_0113	COG1473	amidohydrolase
Axylo_0115	COG1742	UPF0060 membrane protein
Axylo_0118	COG1280	lysine exporter protein (LysE YggA)
Axylo_0123	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Axylo_0125	COG0018	arginyl-trna synthetase
Axylo_0128	COG0395	ABC-type sugar transport system, permease component
Axylo_0129	COG1175	transmembrane transport
Axylo_0130	COG1653	transport
Axylo_0132	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
Axylo_0133	COG1609	Transcriptional regulator
Axylo_0135	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Axylo_0138	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
Axylo_0140	COG0583	DNA-binding transcription factor activity
Axylo_0144	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
Axylo_0145	COG1280	lysine exporter protein (LysE YggA)
Axylo_0146	COG0513	Belongs to the DEAD box helicase family
Axylo_0147	COG5339	Protein conserved in bacteria
Axylo_0148	COG5339	Protein conserved in bacteria
Axylo_0149	COG1228	amidohydrolase
Axylo_0151	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Axylo_0152	COG0601	transmembrane transport
Axylo_0153	COG0747	negative chemotaxis
Axylo_0156	COG2207	Transcriptional regulator
Axylo_0156	COG3708	Transcriptional regulator
Axylo_0158	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Axylo_0165	COG0463	Glycosyl transferase, family 2
Axylo_0167	COG3959	Transketolase, thiamine diphosphate binding domain
Axylo_0174	COG2969	positive regulation of protein catabolic process
Axylo_0175	COG0625	glutathione transferase activity
Axylo_0176	COG2857	Cytochrome c1
Axylo_0177	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Axylo_0178	COG0723	plastoquinol--plastocyanin reductase activity
Axylo_0179	COG1970	mechanosensitive ion channel activity
Axylo_0180	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Axylo_0184	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Axylo_0185	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Axylo_0186	COG0537	adenosine 5'-monophosphoramidase activity
Axylo_0187	COG0140	phosphoribosyl-ATP diphosphatase activity
Axylo_0188	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Axylo_0189	COG0107	imidazoleglycerol-phosphate synthase activity
Axylo_0190	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Axylo_0191	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Axylo_0192	COG0131	Imidazoleglycerol-phosphate dehydratase
Axylo_0193	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Axylo_0194	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Axylo_0195	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Axylo_0196	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Axylo_0198	COG0842	Transport permease protein
Axylo_0199	COG1131	(ABC) transporter
Axylo_0201	COG2853	Lipoprotein
Axylo_0202	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Axylo_0203	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Axylo_0204	COG1127	ABC transporter
Axylo_0207	COG0477	Major facilitator Superfamily
Axylo_0210	COG0583	DNA-binding transcription factor activity
Axylo_0211	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
Axylo_0212	COG0511	ligase activity, forming carbon-carbon bonds
Axylo_0215	COG1984	allophanate hydrolase subunit 2
Axylo_0220	COG0067	glutamate synthase
Axylo_0220	COG0069	glutamate synthase activity
Axylo_0220	COG0070	glutamate synthase
Axylo_0225	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
Axylo_0229	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Axylo_0232	COG1845	cytochrome c oxidase, subunit III
Axylo_0236	COG1612	heme a metabolic process
Axylo_0237	COG0109	protoheme IX farnesyltransferase activity
Axylo_0238	COG1999	signal sequence binding
Axylo_0242	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Axylo_0243	COG2814	Major facilitator Superfamily
Axylo_0247	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Axylo_0248	COG3328	transposase activity
Axylo_0250	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Axylo_0252	COG2801	Transposase and inactivated derivatives
Axylo_0256	COG0456	acetyltransferase
Axylo_0259	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Axylo_0264	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Axylo_0269	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Axylo_0270	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
Axylo_0271	COG2814	Major facilitator Superfamily
Axylo_0272	COG0583	DNA-binding transcription factor activity
Axylo_0273	COG2423	ornithine cyclodeaminase activity
Axylo_0274	COG5001	Diguanylate cyclase
Axylo_0275	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Axylo_0276	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Axylo_0278	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Axylo_0280	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Axylo_0281	COG0463	Glycosyl transferase, family 2
Axylo_0289	COG0737	Belongs to the 5'-nucleotidase family
Axylo_0294	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
Axylo_0295	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
Axylo_0299	COG0840	transmembrane signaling receptor activity
Axylo_0300	COG2814	Major facilitator Superfamily
Axylo_0303	COG3188	usher protein
Axylo_0315	COG1802	Transcriptional regulator
Axylo_0317	COG3069	C4-dicarboxylate transmembrane transporter activity
Axylo_0318	COG1012	belongs to the aldehyde dehydrogenase family
Axylo_0321	COG0589	response to stress
Axylo_0322	COG0431	NADPH-dependent FMN reductase
Axylo_0323	COG3585	molybdate ion transport
Axylo_0327	COG1607	acyl-coa hydrolase
Axylo_0329	COG0243	molybdopterin cofactor binding
Axylo_0329	COG3383	formate dehydrogenase (NAD+) activity
Axylo_0330	COG0243	molybdopterin cofactor binding
Axylo_0330	COG3383	formate dehydrogenase (NAD+) activity
Axylo_0331	COG0437	4 iron, 4 sulfur cluster binding
Axylo_0332	COG2864	formate dehydrogenase
Axylo_0335	COG3276	selenocysteine insertion sequence binding
Axylo_0337	COG1215	transferase activity, transferring glycosyl groups
Axylo_0338	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Axylo_0339	COG1305	Transglutaminase-like
Axylo_0340	COG0709	Synthesizes selenophosphate from selenide and ATP
Axylo_0346	COG1012	belongs to the aldehyde dehydrogenase family
Axylo_0347	COG3284	Transcriptional regulator
Axylo_0348	COG0134	indole-3-glycerol-phosphate synthase activity
Axylo_0349	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Axylo_0350	COG0512	Glutamine amidotransferase of anthranilate synthase
Axylo_0352	COG0546	phosphoglycolate phosphatase activity
Axylo_0354	COG2967	ApaG domain
Axylo_0356	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Axylo_0357	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Axylo_0358	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Axylo_0359	COG0037	tRNA processing
Axylo_0362	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Axylo_0363	COG0583	DNA-binding transcription factor activity
Axylo_0364	COG3473	Maleate cis-trans isomerase
Axylo_0365	COG0583	DNA-binding transcription factor activity
Axylo_0368	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
Axylo_0370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Axylo_0371	COG1024	Enoyl-CoA hydratase
Axylo_0373	COG0356	it plays a direct role in the translocation of protons across the membrane
Axylo_0375	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Axylo_0376	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Axylo_0377	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Axylo_0378	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Axylo_0379	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Axylo_0380	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Axylo_0382	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Axylo_0383	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Axylo_0384	COG0210	DNA helicase
Axylo_0387	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Axylo_0388	COG4221	oxidoreductase activity
Axylo_0390	COG2171	N-acyltransferase activity
Axylo_0392	COG2195	Cleaves the N-terminal amino acid of tripeptides
Axylo_0394	COG4608	Belongs to the ABC transporter superfamily
Axylo_0395	COG0444	Belongs to the ABC transporter superfamily
Axylo_0397	COG0601	transmembrane transport
Axylo_0398	COG0747	negative chemotaxis
Axylo_0399	COG2988	succinylglutamate desuccinylase activity
Axylo_0401	COG0583	DNA-binding transcription factor activity
Axylo_0402	COG0747	negative chemotaxis
Axylo_0404	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Axylo_0405	COG1024	Enoyl-CoA hydratase
Axylo_0406	COG1024	Enoyl-CoA hydratase
Axylo_0408	COG1309	transcriptional regulator
Axylo_0411	COG1250	3-hydroxyacyl-CoA dehydrogenase
Axylo_0416	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Axylo_0417	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Axylo_0420	COG0179	Fumarylacetoacetate (FAA) hydrolase
Axylo_0422	COG0559	Belongs to the binding-protein-dependent transport system permease family
Axylo_0424	COG1129	ABC transporter
Axylo_0427	COG1802	Transcriptional regulator
Axylo_0429	COG0583	DNA-binding transcription factor activity
Axylo_0431	COG2988	succinylglutamate desuccinylase activity
Axylo_0433	COG2918	glutathione biosynthetic process
Axylo_0439	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
Axylo_0440	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Axylo_0442	COG2721	sulfolactate sulfo-lyase activity
Axylo_0443	COG2721	sulfolactate sulfo-lyase activity
Axylo_0444	COG2188	Transcriptional regulator
Axylo_0445	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Axylo_0446	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Axylo_0446	COG2813	Specifically methylates the guanine in position
Axylo_0447	COG2223	nitrite transmembrane transporter activity
Axylo_0449	COG2860	membrane
Axylo_0450	COG1802	Transcriptional regulator
Axylo_0451	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
Axylo_0452	COG1984	allophanate hydrolase subunit 2
Axylo_0453	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
Axylo_0456	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Axylo_0459	COG2132	Multicopper oxidase
Axylo_0464	COG0745	RESPONSE REGULATOR receiver
Axylo_0465	COG2226	methyltransferase
Axylo_0468	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Axylo_0470	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
Axylo_0472	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Axylo_0473	COG0351	phosphomethylpyrimidine kinase
Axylo_0474	COG2022	thiamine diphosphate biosynthetic process
Axylo_0475	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Axylo_0476	COG4771	TonB-dependent receptor
Axylo_0478	COG2186	Transcriptional regulator
Axylo_0481	COG1063	alcohol dehydrogenase
Axylo_0483	COG0765	amino acid transport
Axylo_0484	COG1126	abc transporter atp-binding protein
Axylo_0485	COG4948	Mandelate Racemase Muconate Lactonizing
Axylo_0486	COG0246	Mannitol dehydrogenase
Axylo_0489	COG1194	a g-specific adenine glycosylase
Axylo_0491	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
Axylo_0492	COG2177	Part of the ABC transporter FtsEX involved in
Axylo_0493	COG2884	Cell division ATP-binding protein ftsE
Axylo_0494	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Axylo_0495	COG4597	amino acid ABC transporter
Axylo_0496	COG0765	amino acid transport
Axylo_0497	COG1126	abc transporter atp-binding protein
Axylo_0502	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Axylo_0503	COG2081	HI0933 family
Axylo_0505	COG1605	Chorismate mutase
Axylo_0505	COG0077	Prephenate dehydratase
Axylo_0511	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Axylo_0512	COG0477	Major facilitator Superfamily
Axylo_0514	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
Axylo_0515	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Axylo_0519	COG0237	dephospho-CoA kinase activity
Axylo_0520	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
Axylo_0524	COG1538	Outer membrane efflux protein
Axylo_0526	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Axylo_0527	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
Axylo_0530	COG3833	ABC-type maltose transport systems, permease component
Axylo_0532	COG3842	ATPase activity
Axylo_0536	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Axylo_0540	COG0559	Belongs to the binding-protein-dependent transport system permease family
Axylo_0543	COG0410	ABC transporter
Axylo_0547	COG3706	GGDEF domain
Axylo_0550	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_0551	COG1024	Enoyl-CoA hydratase
Axylo_0559	COG4638	Rieske (2fe-2S)
Axylo_0560	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
Axylo_0561	COG1335	isochorismatase
Axylo_0562	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_0564	COG0741	lytic transglycosylase activity
Axylo_0565	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Axylo_0569	COG1678	Uncharacterized ACR, COG1678
Axylo_0570	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Axylo_0574	COG1126	abc transporter atp-binding protein
Axylo_0575	COG0765	amino acid transport
Axylo_0577	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Axylo_0579	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Axylo_0581	COG3328	transposase activity
Axylo_0582	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Axylo_0584	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Axylo_0585	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Axylo_0588	COG1175	transmembrane transport
Axylo_0590	COG0642	Histidine kinase
Axylo_0593	COG0557	exoribonuclease II activity
Axylo_0594	COG3150	esterase
Axylo_0595	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Axylo_0596	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Axylo_0597	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Axylo_0598	COG0511	ligase activity, forming carbon-carbon bonds
Axylo_0599	COG0439	Biotin carboxylase
Axylo_0600	COG2264	protein methyltransferase activity
Axylo_0602	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
Axylo_0602	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
Axylo_0607	COG1696	Membrane protein involved in D-alanine export
Axylo_0608	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Axylo_0614	COG1522	sequence-specific DNA binding
Axylo_0615	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_0617	COG0583	DNA-binding transcription factor activity
Axylo_0620	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Axylo_0621	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Axylo_0621	COG1042	CoA-binding domain protein
Axylo_0621	COG0045	succinate-CoA ligase (ADP-forming) activity
Axylo_0622	COG1335	isochorismatase
Axylo_0623	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Axylo_0624	COG1116	anion transmembrane transporter activity
Axylo_0627	COG3028	Belongs to the UPF0307 family
Axylo_0628	COG0312	modulator of DNA gyrase
Axylo_0629	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
Axylo_0631	COG0559	Belongs to the binding-protein-dependent transport system permease family
Axylo_0632	COG4177	L-phenylalanine transmembrane transporter activity
Axylo_0635	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Axylo_0636	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Axylo_0637	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Axylo_0639	COG0316	Belongs to the HesB IscA family
Axylo_0640	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
Axylo_0642	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Axylo_0644	COG1280	lysine exporter protein (LysE YggA)
Axylo_0645	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Axylo_0646	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Axylo_0649	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Axylo_0649	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Axylo_0652	COG2766	serine protein kinase
Axylo_0653	COG2718	Belongs to the UPF0229 family
Axylo_0654	COG2719	SpoVR family
Axylo_0657	COG1942	4-Oxalocrotonate Tautomerase
Axylo_0659	COG0456	acetyltransferase
Axylo_0661	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Axylo_0672	COG4789	Type iii secretion
Axylo_0687	COG4669	(LipO)protein
Axylo_0693	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Axylo_0694	COG4790	Type iii secretion
Axylo_0695	COG4794	Type iii secretion
Axylo_0696	COG4791	protein targeting
Axylo_0697	COG4792	protein secretion
Axylo_0703	COG2208	phosphoserine phosphatase activity
Axylo_0703	COG2770	Histidine kinase
Axylo_0705	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Axylo_0706	COG2172	sigma factor antagonist activity
Axylo_0707	COG1366	Belongs to the anti-sigma-factor antagonist family
Axylo_0715	COG0741	lytic transglycosylase activity
Axylo_0715	COG1388	LysM domain
Axylo_0716	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Axylo_0717	COG2226	methyltransferase
Axylo_0718	COG0328	RNA-DNA hybrid ribonuclease activity
Axylo_0720	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Axylo_0721	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Axylo_0724	COG1671	Belongs to the UPF0178 family
Axylo_0727	COG0786	glutamate:sodium symporter activity
Axylo_0729	COG0463	Glycosyl transferase, family 2
Axylo_0730	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Axylo_0733	COG0583	DNA-binding transcription factor activity
Axylo_0737	COG0559	Belongs to the binding-protein-dependent transport system permease family
Axylo_0741	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Axylo_0743	COG0583	DNA-binding transcription factor activity
Axylo_0744	COG1380	Effector of murein hydrolase LrgA
Axylo_0747	COG0697	spore germination
Axylo_0748	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Axylo_0751	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Axylo_0753	COG1522	sequence-specific DNA binding
Axylo_0756	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
Axylo_0757	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Axylo_0760	COG0823	Involved in the tonB-independent uptake of proteins
Axylo_0762	COG0848	biopolymer transport protein
Axylo_0763	COG0811	peptide transport
Axylo_0764	COG0824	Thioesterase
Axylo_0765	COG0442	prolyl-tRNA aminoacylation
Axylo_0771	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Axylo_0773	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
Axylo_0774	COG2084	Dehydrogenase
Axylo_0775	COG0405	Gamma-glutamyltransferase
Axylo_0782	COG0129	dihydroxy-acid dehydratase activity
Axylo_0783	COG4654	Cytochrome c, class I
Axylo_0784	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Axylo_0786	COG1522	sequence-specific DNA binding
Axylo_0795	COG1473	amidohydrolase
Axylo_0796	COG0418	dihydroorotase activity
Axylo_0798	COG2001	Belongs to the MraZ family
Axylo_0799	COG0275	rRNA processing
Axylo_0800	COG3116	cell division
Axylo_0802	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Axylo_0803	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Axylo_0804	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Axylo_0806	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Axylo_0807	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Axylo_0808	COG1181	Belongs to the D-alanine--D-alanine ligase family
Axylo_0809	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Axylo_0811	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Axylo_0812	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
Axylo_0814	COG0739	heme binding
Axylo_0815	COG0653	protein targeting
Axylo_0818	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_0819	COG0028	Belongs to the TPP enzyme family
Axylo_0821	COG0300	oxidoreductase activity
Axylo_0822	COG1522	sequence-specific DNA binding
Axylo_0825	COG2239	Acts as a magnesium transporter
Axylo_0826	COG1607	acyl-coa hydrolase
Axylo_0827	COG2855	membrane
Axylo_0828	COG0583	DNA-binding transcription factor activity
Axylo_0829	COG1473	amidohydrolase
Axylo_0830	COG0318	PFAM AMP-dependent synthetase and ligase
Axylo_0831	COG0483	inositol monophosphate 1-phosphatase activity
Axylo_0832	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Axylo_0832	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
Axylo_0833	COG1501	Belongs to the glycosyl hydrolase 31 family
Axylo_0834	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Axylo_0835	COG2011	ABC-type metal ion transport system permease component
Axylo_0846	COG0840	transmembrane signaling receptor activity
Axylo_0847	COG0583	DNA-binding transcription factor activity
Axylo_0849	COG0735	belongs to the Fur family
Axylo_0854	COG2818	Glycosylase
Axylo_0855	COG1368	sulfuric ester hydrolase activity
Axylo_0856	COG2982	Protein involved in outer membrane biogenesis
Axylo_0860	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_0866	COG2154	pterin-4-alpha-carbinolamine dehydratase
Axylo_0871	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Axylo_0873	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
Axylo_0874	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Axylo_0875	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Axylo_0876	COG1929	Belongs to the glycerate kinase type-1 family
Axylo_0877	COG0469	pyruvate kinase activity
Axylo_0878	COG0700	Nucleoside recognition
Axylo_0879	COG1960	acyl-CoA dehydrogenase activity
Axylo_0880	COG0242	peptide deformylase activity
Axylo_0882	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Axylo_0884	COG0204	Acyl-transferase
Axylo_0885	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
Axylo_0886	COG0751	glycine-tRNA ligase activity
Axylo_0887	COG0752	glycyl-tRNA synthetase alpha subunit
Axylo_0888	COG1024	Enoyl-CoA hydratase
Axylo_0891	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Axylo_0892	COG2030	dehydratase
Axylo_0893	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_0897	COG2070	2-Nitropropane dioxygenase
Axylo_0899	COG0318	PFAM AMP-dependent synthetase and ligase
Axylo_0900	COG0183	Belongs to the thiolase family
Axylo_0902	COG1960	acyl-CoA dehydrogenase activity
Axylo_0904	COG1024	Enoyl-CoA hydratase
Axylo_0906	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
Axylo_0908	COG2301	Belongs to the HpcH HpaI aldolase family
Axylo_0909	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Axylo_0911	COG0617	tRNA 3'-terminal CCA addition
Axylo_0914	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Axylo_0916	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Axylo_0917	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Axylo_0918	COG0586	Pfam SNARE associated Golgi protein
Axylo_0920	COG0860	N-Acetylmuramoyl-L-alanine amidase
Axylo_0921	COG0114	fumarate hydratase activity
Axylo_0923	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_0926	COG0531	amino acid
Axylo_0927	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Axylo_0929	COG1960	acyl-CoA dehydrogenase activity
Axylo_0930	COG0583	DNA-binding transcription factor activity
Axylo_0932	COG0579	oxidoreductase
Axylo_0934	COG0259	pyridoxamine-phosphate oxidase activity
Axylo_0937	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Axylo_0938	COG0577	efflux transmembrane transporter activity
Axylo_0938	COG1136	(ABC) transporter
Axylo_0939	COG1538	Outer membrane efflux protein
Axylo_0940	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Axylo_0947	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Axylo_0949	COG0800	Aldolase
Axylo_0953	COG0463	Glycosyl transferase, family 2
Axylo_0953	COG1216	Glycosyl transferase, family 2
Axylo_0954	COG0410	ABC transporter
Axylo_0955	COG0411	ABC transporter
Axylo_0958	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_0959	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
Axylo_0963	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
Axylo_0964	COG4638	Rieske (2fe-2S)
Axylo_0969	COG0747	negative chemotaxis
Axylo_0971	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Axylo_0972	COG0444	Belongs to the ABC transporter superfamily
Axylo_0973	COG4608	Belongs to the ABC transporter superfamily
Axylo_0977	COG2746	aminoglycoside 3-N-acetyltransferase activity
Axylo_0978	COG0488	(ABC) transporter
Axylo_0981	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
Axylo_0982	COG2894	cell division
Axylo_0983	COG0850	regulation of cytokinetic process
Axylo_0984	COG1414	Transcriptional regulator
Axylo_0985	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Axylo_0986	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Axylo_0988	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Axylo_0990	COG1294	oxidase, subunit
Axylo_0991	COG0514	ATP-dependent DNA helicase (RecQ)
Axylo_0993	COG0745	RESPONSE REGULATOR receiver
Axylo_0995	COG2255	four-way junction helicase activity
Axylo_0997	COG1090	epimerase
Axylo_0998	COG0632	four-way junction helicase activity
Axylo_1003	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Axylo_1005	COG0006	proline dipeptidase activity
Axylo_1008	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Axylo_1009	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Axylo_1012	COG4783	chaperone-mediated protein folding
Axylo_1020	COG2814	Major facilitator Superfamily
Axylo_1023	COG0513	Belongs to the DEAD box helicase family
Axylo_1026	COG1058	Belongs to the CinA family
Axylo_1026	COG1546	Belongs to the CinA family
Axylo_1027	COG1414	Transcriptional regulator
Axylo_1030	COG0167	dihydroorotate dehydrogenase activity
Axylo_1031	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
Axylo_1032	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
Axylo_1034	COG0583	DNA-binding transcription factor activity
Axylo_1045	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
Axylo_1049	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Axylo_1050	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Axylo_1051	COG0735	belongs to the Fur family
Axylo_1052	COG0497	DNA recombination
Axylo_1053	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Axylo_1054	COG1420	regulation of RNA biosynthetic process
Axylo_1055	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Axylo_1057	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Axylo_1059	COG0443	Heat shock 70 kDa protein
Axylo_1060	COG0484	heat shock protein binding
Axylo_1063	COG1595	DNA-templated transcription, initiation
Axylo_1065	COG0612	Peptidase, M16
Axylo_1070	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Axylo_1077	COG0840	transmembrane signaling receptor activity
Axylo_1078	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Axylo_1081	COG0745	RESPONSE REGULATOR receiver
Axylo_1082	COG2205	protein histidine kinase activity
Axylo_1083	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
Axylo_1084	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
Axylo_1088	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Axylo_1090	COG1193	negative regulation of DNA recombination
Axylo_1091	COG0492	ferredoxin-NADP+ reductase activity
Axylo_1092	COG1674	ftsk spoiiie
Axylo_1093	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
Axylo_1094	COG0251	oxidation-reduction process
Axylo_1095	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
Axylo_1096	COG0517	IMP dehydrogenase activity
Axylo_1096	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Axylo_1100	COG0601	transmembrane transport
Axylo_1103	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Axylo_1104	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Axylo_1105	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Axylo_1113	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Axylo_1117	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_1118	COG3022	response to hydroperoxide
Axylo_1119	COG1289	transmembrane transporter activity
Axylo_1120	COG0028	Belongs to the TPP enzyme family
Axylo_1121	COG0440	acetolactate synthase activity
Axylo_1122	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Axylo_1123	COG1183	phosphatidylcholine synthase activity
Axylo_1125	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Axylo_1126	COG1185	polyribonucleotide nucleotidyltransferase activity
Axylo_1128	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Axylo_1131	COG4774	siderophore transport
Axylo_1134	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Axylo_1140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Axylo_1142	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Axylo_1146	COG0149	triose-phosphate isomerase activity
Axylo_1147	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Axylo_1150	COG0582	viral genome integration into host DNA
Axylo_1169	COG1595	DNA-templated transcription, initiation
Axylo_1170	COG3712	iron ion homeostasis
Axylo_1175	COG1595	DNA-templated transcription, initiation
Axylo_1182	COG4191	Histidine kinase
Axylo_1183	COG4566	intracellular signal transduction
Axylo_1185	COG0642	Histidine kinase
Axylo_1188	COG2851	Citrate transporter
Axylo_1189	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_1193	COG1278	Cold shock
Axylo_1196	COG3813	Protein conserved in bacteria
Axylo_1197	COG2354	Protein conserved in bacteria
Axylo_1200	COG4772	TonB-dependent receptor
Axylo_1201	COG1522	sequence-specific DNA binding
Axylo_1207	COG0747	negative chemotaxis
Axylo_1211	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Axylo_1214	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Axylo_1215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Axylo_1216	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Axylo_1220	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Axylo_1221	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Axylo_1222	COG1309	transcriptional regulator
Axylo_1223	COG0583	DNA-binding transcription factor activity
Axylo_1227	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
Axylo_1232	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Axylo_1233	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Axylo_1234	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Axylo_1235	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Axylo_1236	COG0649	NAD binding
Axylo_1237	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
Axylo_1239	COG1034	ATP synthesis coupled electron transport
Axylo_1240	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Axylo_1241	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Axylo_1243	COG0713	ATP synthesis coupled electron transport
Axylo_1246	COG1007	ATP synthesis coupled electron transport
Axylo_1248	COG4774	siderophore transport
Axylo_1249	COG0560	Phosphoserine phosphatase
Axylo_1250	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Axylo_1251	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Axylo_1252	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Axylo_1254	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Axylo_1255	COG0450	alkyl hydroperoxide reductase
Axylo_1256	COG2205	protein histidine kinase activity
Axylo_1257	COG0745	RESPONSE REGULATOR receiver
Axylo_1258	COG1214	PFAM Peptidase M22, glycoprotease
Axylo_1259	COG1573	uracil-dna glycosylase
Axylo_1260	COG0477	Major facilitator Superfamily
Axylo_1261	COG1196	nuclear chromosome segregation
Axylo_1263	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Axylo_1264	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Axylo_1266	COG2917	probably involved in intracellular septation
Axylo_1267	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Axylo_1268	COG1122	ATPase activity
Axylo_1269	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
Axylo_1270	COG1268	BioY protein
Axylo_1273	COG0411	ABC transporter
Axylo_1277	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Axylo_1283	COG0411	ABC transporter
Axylo_1284	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Axylo_1285	COG2878	Part of a membrane complex involved in electron transport
Axylo_1288	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
Axylo_1289	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
Axylo_1290	COG0251	oxidation-reduction process
Axylo_1292	COG3228	Belongs to the MtfA family
Axylo_1293	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Axylo_1295	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Axylo_1296	COG0133	tryptophan synthase activity
Axylo_1297	COG0159	tryptophan synthase activity
Axylo_1298	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Axylo_1299	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
Axylo_1300	COG1530	ribonuclease E activity
Axylo_1301	COG0564	pseudouridine synthase activity
Axylo_1302	COG0546	phosphoglycolate phosphatase activity
Axylo_1303	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Axylo_1304	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
Axylo_1307	COG0424	maF-like protein
Axylo_1308	COG1399	metal-binding, possibly nucleic acid-binding protein
Axylo_1309	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Axylo_1310	COG0416	fatty acid biosynthetic process
Axylo_1311	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Axylo_1312	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Axylo_1314	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Axylo_1315	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Axylo_1320	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Axylo_1321	COG0481	GTPase activity
Axylo_1322	COG0681	Belongs to the peptidase S26 family
Axylo_1323	COG0571	ribonuclease III activity
Axylo_1324	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Axylo_1325	COG1381	Involved in DNA repair and RecF pathway recombination
Axylo_1327	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Axylo_1329	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_1331	COG0667	Aldo Keto reductase
Axylo_1335	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Axylo_1340	COG0583	DNA-binding transcription factor activity
Axylo_1342	COG0791	NLP P60 protein
Axylo_1343	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Axylo_1344	COG3193	protein, possibly involved in utilization of glycolate and propanediol
Axylo_1347	COG0697	spore germination
Axylo_1348	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
Axylo_1356	COG2153	protein acetylation
Axylo_1358	COG1446	asparaginase
Axylo_1359	COG4172	Belongs to the ABC transporter superfamily
Axylo_1360	COG0747	negative chemotaxis
Axylo_1362	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Axylo_1367	COG0504	CTP synthase activity
Axylo_1369	COG0148	phosphopyruvate hydratase activity
Axylo_1372	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
Axylo_1374	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Axylo_1385	COG0039	L-malate dehydrogenase activity
Axylo_1386	COG2188	Transcriptional regulator
Axylo_1387	COG2009	succinate dehydrogenase
Axylo_1388	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
Axylo_1389	COG1053	succinate dehydrogenase
Axylo_1390	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
Axylo_1391	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
Axylo_1392	COG0372	Belongs to the citrate synthase family
Axylo_1395	COG0281	malic enzyme
Axylo_1395	COG0280	phosphate acetyltransferase
Axylo_1397	COG1297	OPT oligopeptide transporter protein
Axylo_1398	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Axylo_1401	COG2515	1-aminocyclopropane-1-carboxylate deaminase
Axylo_1402	COG1522	sequence-specific DNA binding
Axylo_1403	COG0567	Dehydrogenase, E1 component
Axylo_1404	COG0508	dehydrogenase complex catalyzes the overall conversion of
Axylo_1405	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Axylo_1406	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
Axylo_1407	COG1595	DNA-templated transcription, initiation
Axylo_1408	COG3712	iron ion homeostasis
Axylo_1409	COG4774	siderophore transport
Axylo_1414	COG0180	Tryptophanyl-tRNA synthetase
Axylo_1416	COG2183	response to ionizing radiation
Axylo_1417	COG1199	ATP-dependent helicase activity
Axylo_1419	COG0564	pseudouridine synthase activity
Axylo_1421	COG3243	poly(R)-hydroxyalkanoic acid synthase
Axylo_1422	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_1423	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
Axylo_1428	COG2831	hemolysin activation secretion protein
Axylo_1431	COG3328	transposase activity
Axylo_1433	COG2823	Periplasmic or secreted lipoprotein
Axylo_1435	COG3237	CsbD-like
Axylo_1437	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Axylo_1437	COG0189	ligase activity
Axylo_1438	COG0189	ligase activity
Axylo_1438	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Axylo_1439	COG1132	(ABC) transporter
Axylo_1442	COG2833	Protein of unknown function (DUF455)
Axylo_1443	COG2258	MOSC domain
Axylo_1444	COG2951	lytic endotransglycosylase activity
Axylo_1447	COG1960	acyl-CoA dehydrogenase activity
Axylo_1449	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Axylo_1451	COG1696	Membrane protein involved in D-alanine export
Axylo_1455	COG1215	transferase activity, transferring glycosyl groups
Axylo_1457	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
Axylo_1459	COG0582	viral genome integration into host DNA
Axylo_1470	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Axylo_1470	COG2755	lipolytic protein G-D-S-L family
Axylo_1479	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Axylo_1482	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
Axylo_1486	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Axylo_1487	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Axylo_1491	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
Axylo_1492	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
Axylo_1493	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Axylo_1499	COG2951	lytic endotransglycosylase activity
Axylo_1500	COG0123	including yeast histone deacetylase and acetoin utilization protein
Axylo_1505	COG2985	domain, Protein
Axylo_1506	COG1960	acyl-CoA dehydrogenase activity
Axylo_1507	COG0450	alkyl hydroperoxide reductase
Axylo_1509	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
Axylo_1510	COG4208	sulfate ABC transporter
Axylo_1512	COG0175	sulfate reduction
Axylo_1518	COG0335	large ribosomal subunit rRNA binding
Axylo_1520	COG1162	GTPase activity
Axylo_1521	COG0501	Belongs to the peptidase M48B family
Axylo_1522	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
Axylo_1523	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Axylo_1524	COG3327	negative regulation of DNA-templated transcription, initiation
Axylo_1525	COG3396	Phenylacetate-CoA oxygenase
Axylo_1526	COG3460	Phenylacetate-CoA oxygenase
Axylo_1527	COG3396	Phenylacetate-CoA oxygenase
Axylo_1528	COG2151	metal-sulfur cluster biosynthetic enzyme
Axylo_1529	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Axylo_1530	COG1012	belongs to the aldehyde dehydrogenase family
Axylo_1531	COG1024	Enoyl-CoA hydratase
Axylo_1532	COG2050	protein possibly involved in aromatic compounds catabolism
Axylo_1534	COG0534	Mate efflux family protein
Axylo_1536	COG0254	rRNA binding
Axylo_1537	COG3483	tryptophan 2,3-dioxygenase activity
Axylo_1539	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
Axylo_1540	COG2003	Belongs to the UPF0758 family
Axylo_1543	COG0625	glutathione transferase activity
Axylo_1544	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Axylo_1546	COG0745	RESPONSE REGULATOR receiver
Axylo_1549	COG0523	cobalamin synthesis protein
Axylo_1550	COG0523	cobalamin synthesis protein
Axylo_1551	COG0583	DNA-binding transcription factor activity
Axylo_1553	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Axylo_1554	COG1187	pseudouridine synthase activity
Axylo_1555	COG0779	Required for maturation of 30S ribosomal subunits
Axylo_1556	COG2251	uridine kinase activity
Axylo_1556	COG0195	Participates in both transcription termination and antitermination
Axylo_1557	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Axylo_1558	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Axylo_1559	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Axylo_1562	COG0583	DNA-binding transcription factor activity
Axylo_1564	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_1565	COG1473	amidohydrolase
Axylo_1566	COG1611	Belongs to the LOG family
Axylo_1567	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Axylo_1567	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Axylo_1569	COG0412	Dienelactone hydrolase
Axylo_1570	COG1283	sodium-dependent phosphate transmembrane transporter activity
Axylo_1571	COG1760	l-serine dehydratase
Axylo_1572	COG0501	Belongs to the peptidase M48B family
Axylo_1576	COG0583	DNA-binding transcription factor activity
Axylo_1577	COG3842	ATPase activity
Axylo_1579	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Axylo_1580	COG1840	ABC-type Fe3 transport system, periplasmic component
Axylo_1584	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_1586	COG1722	exodeoxyribonuclease VII activity
Axylo_1587	COG0142	geranyltranstransferase activity
Axylo_1588	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Axylo_1589	COG1469	GTP cyclohydrolase I activity
Axylo_1590	COG3739	integral membrane protein
Axylo_1591	COG0360	Binds together with S18 to 16S ribosomal RNA
Axylo_1592	COG2965	DNA replication, synthesis of RNA primer
Axylo_1593	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Axylo_1594	COG0359	binds to the 23S rRNA
Axylo_1596	COG0305	Participates in initiation and elongation during chromosome replication
Axylo_1598	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Axylo_1605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Axylo_1609	COG0493	'glutamate synthase
Axylo_1615	COG0540	Belongs to the ATCase OTCase family
Axylo_1620	COG0642	Histidine kinase
Axylo_1622	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Axylo_1623	COG2137	regulation of response to DNA damage stimulus
Axylo_1624	COG0583	DNA-binding transcription factor activity
Axylo_1625	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Axylo_1626	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Axylo_1628	COG0045	succinate-CoA ligase (ADP-forming) activity
Axylo_1629	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
Axylo_1630	COG0861	Integral membrane protein TerC family
Axylo_1631	COG0861	Integral membrane protein TerC family
Axylo_1633	COG0181	hydroxymethylbilane synthase activity
Axylo_1637	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
Axylo_1639	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_1642	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_1643	COG0411	ABC transporter
Axylo_1645	COG0559	Belongs to the binding-protein-dependent transport system permease family
Axylo_1649	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
Axylo_1650	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Axylo_1652	COG0436	Aminotransferase
Axylo_1656	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Axylo_1657	COG0308	aminopeptidase N
Axylo_1660	COG0312	modulator of DNA gyrase
Axylo_1661	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Axylo_1662	COG0277	FAD linked oxidase domain protein
Axylo_1663	COG0308	aminopeptidase N
Axylo_1666	COG0312	modulator of DNA gyrase
Axylo_1667	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Axylo_1668	COG0277	FAD linked oxidase domain protein
Axylo_1669	COG0308	aminopeptidase N
Axylo_1672	COG0312	modulator of DNA gyrase
Axylo_1673	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Axylo_1674	COG0277	FAD linked oxidase domain protein
Axylo_1675	COG0277	FAD linked oxidase domain protein
Axylo_1676	COG0277	FAD linked oxidase domain protein
Axylo_1677	COG0247	lactate metabolic process
Axylo_1678	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
Axylo_1679	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
Axylo_1680	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
Axylo_1683	COG0583	DNA-binding transcription factor activity
Axylo_1684	COG0482	sulfurtransferase activity
Axylo_1685	COG0730	response to heat
Axylo_1686	COG0625	glutathione transferase activity
Axylo_1688	COG3909	cytochrome
Axylo_1689	COG2801	Transposase and inactivated derivatives
Axylo_1698	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
Axylo_1702	COG2801	Transposase and inactivated derivatives
Axylo_1725	COG0697	spore germination
Axylo_1732	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
Axylo_1734	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Axylo_1735	COG0069	glutamate synthase activity
Axylo_1736	COG2391	methyltransferase activity
Axylo_1737	COG0679	Auxin Efflux Carrier
Axylo_1739	COG2153	protein acetylation
Axylo_1743	COG0557	exoribonuclease II activity
Axylo_1744	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Axylo_1746	COG3128	pkhd-type hydroxylase
Axylo_1747	COG0776	regulation of translation
Axylo_1752	COG0745	RESPONSE REGULATOR receiver
Axylo_1753	COG0642	Histidine kinase
Axylo_1754	COG3158	transport of potassium into the cell
Axylo_1755	COG0137	argininosuccinate synthase activity
Axylo_1756	COG1538	Outer membrane efflux protein
Axylo_1758	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Axylo_1760	COG5002	protein histidine kinase activity
Axylo_1761	COG0583	DNA-binding transcription factor activity
Axylo_1762	COG3618	amidohydrolase
Axylo_1766	COG0596	Alpha beta hydrolase
Axylo_1766	COG2945	thiolester hydrolase activity
Axylo_1767	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Axylo_1768	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Axylo_1772	COG0747	negative chemotaxis
Axylo_1774	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Axylo_1776	COG0402	S-adenosylhomocysteine deaminase activity
Axylo_1778	COG4608	Belongs to the ABC transporter superfamily
Axylo_1781	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Axylo_1782	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
Axylo_1784	COG3642	lipopolysaccharide core region biosynthetic process
Axylo_1786	COG3842	ATPase activity
Axylo_1787	COG1176	ABC-type spermidine putrescine transport system, permease component I
Axylo_1788	COG1177	transmembrane transport
Axylo_1794	COG1960	acyl-CoA dehydrogenase activity
Axylo_1796	COG0704	Plays a role in the regulation of phosphate uptake
Axylo_1798	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
Axylo_1799	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Axylo_1799	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
Axylo_1800	COG1643	Atp-dependent helicase
Axylo_1801	COG0395	ABC-type sugar transport system, permease component
Axylo_1802	COG1116	anion transmembrane transporter activity
Axylo_1805	COG0438	transferase activity, transferring glycosyl groups
Axylo_1806	COG0726	polysaccharide deacetylase
Axylo_1809	COG0726	polysaccharide deacetylase
Axylo_1814	COG1132	(ABC) transporter
Axylo_1815	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Axylo_1815	COG0475	glutathione-regulated potassium exporter activity
Axylo_1818	COG4251	negative regulation of phosphorylation
Axylo_1818	COG5001	Diguanylate cyclase
Axylo_1818	COG2203	Gaf domain
Axylo_1818	COG3706	GGDEF domain
Axylo_1827	COG1530	ribonuclease E activity
Axylo_1836	COG0583	DNA-binding transcription factor activity
Axylo_1839	COG1250	3-hydroxyacyl-CoA dehydrogenase
Axylo_1841	COG0477	Major facilitator Superfamily
Axylo_1843	COG0154	amidase activity
Axylo_1847	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Axylo_1850	COG0495	leucyl-tRNA aminoacylation
Axylo_1851	COG2814	Major facilitator Superfamily
Axylo_1852	COG1846	Transcriptional regulator
Axylo_1854	COG1686	Belongs to the peptidase S11 family
Axylo_1861	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Axylo_1862	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Axylo_1863	COG2814	Major facilitator Superfamily
Axylo_1864	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Axylo_1866	COG4176	ABC-type proline glycine betaine transport system permease component
Axylo_1867	COG3448	diguanylate cyclase activity
Axylo_1867	COG4175	Glycine betaine
Axylo_1870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Axylo_1871	COG2706	6-phosphogluconolactonase activity
Axylo_1872	COG4214	carbohydrate transport
Axylo_1873	COG1129	ABC transporter
Axylo_1874	COG4213	ABC transporter substrate-binding protein
Axylo_1878	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Axylo_1879	COG0583	DNA-binding transcription factor activity
Axylo_1880	COG1960	acyl-CoA dehydrogenase activity
Axylo_1881	COG1960	acyl-CoA dehydrogenase activity
Axylo_1882	COG0183	Belongs to the thiolase family
Axylo_1884	COG1802	Transcriptional regulator
Axylo_1886	COG1024	Enoyl-CoA hydratase
Axylo_1887	COG0318	PFAM AMP-dependent synthetase and ligase
Axylo_1889	COG0667	Aldo Keto reductase
Axylo_1892	COG4120	Belongs to the binding-protein-dependent transport system permease family
Axylo_1895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Axylo_1897	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Axylo_1902	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
Axylo_1903	COG0725	ABC transporter, periplasmic molybdate-binding protein
Axylo_1904	COG4149	molybdate abc transporter
Axylo_1905	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
Axylo_1910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Axylo_1911	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Axylo_1912	COG1538	Outer membrane efflux protein
Axylo_1913	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
Axylo_1914	COG0736	holo-[acyl-carrier-protein] synthase activity
Axylo_1915	COG1472	Belongs to the glycosyl hydrolase 3 family
Axylo_1916	COG0322	excinuclease ABC activity
Axylo_1917	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Axylo_1919	COG0473	3-isopropylmalate dehydrogenase activity
Axylo_1920	COG0583	DNA-binding transcription factor activity
Axylo_1921	COG1858	cytochrome C peroxidase
Axylo_1922	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Axylo_1922	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Axylo_1923	COG2224	Isocitrate lyase
Axylo_1924	COG0583	DNA-binding transcription factor activity
Axylo_1927	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Axylo_1930	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
Axylo_1930	COG4106	trans-aconitate 2-methyltransferase activity
Axylo_1931	COG4106	trans-aconitate 2-methyltransferase activity
Axylo_1931	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
Axylo_1933	COG0156	8-amino-7-oxononanoate synthase activity
Axylo_1937	COG3278	Belongs to the heme-copper respiratory oxidase family
Axylo_1941	COG0348	domain, Protein
Axylo_1945	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_1950	COG1012	belongs to the aldehyde dehydrogenase family
Axylo_1952	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Axylo_1954	COG0765	amino acid transport
Axylo_1955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Axylo_1956	COG1396	sequence-specific DNA binding
Axylo_1959	COG3546	catalase activity
Axylo_1965	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
Axylo_1967	COG0438	transferase activity, transferring glycosyl groups
Axylo_1971	COG1566	PFAM secretion protein HlyD family protein
Axylo_1974	COG0583	DNA-binding transcription factor activity
Axylo_1975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Axylo_1976	COG0586	Pfam SNARE associated Golgi protein
Axylo_1979	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Axylo_1982	COG4608	Belongs to the ABC transporter superfamily
Axylo_1983	COG0444	Belongs to the ABC transporter superfamily
Axylo_1984	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Axylo_1985	COG0601	transmembrane transport
Axylo_1986	COG0583	DNA-binding transcription factor activity
Axylo_1987	COG1764	response to oxidative stress
Axylo_1988	COG2205	protein histidine kinase activity
Axylo_1989	COG0745	RESPONSE REGULATOR receiver
Axylo_1997	COG1802	Transcriptional regulator
Axylo_2000	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Axylo_2003	COG0583	DNA-binding transcription factor activity
Axylo_2005	COG2084	Dehydrogenase
Axylo_2007	COG1917	Cupin 2, conserved barrel domain protein
Axylo_2007	COG2207	Transcriptional regulator
Axylo_2010	COG2267	carboxylic ester hydrolase activity
Axylo_2015	COG1280	lysine exporter protein (LysE YggA)
Axylo_2016	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_2017	COG0840	transmembrane signaling receptor activity
Axylo_2024	COG3188	usher protein
Axylo_2025	COG3121	Chaperone
Axylo_2031	COG2197	response regulator
Axylo_2033	COG3300	MHYT domain
Axylo_2033	COG5001	Diguanylate cyclase
Axylo_2035	COG3539	Fimbrial protein
Axylo_2037	COG3188	usher protein
Axylo_2040	COG0745	RESPONSE REGULATOR receiver
Axylo_2041	COG0642	Histidine kinase
Axylo_2042	COG1475	DNA binding
Axylo_2044	COG3969	phosphoadenosine phosphosulfate
Axylo_2045	COG1971	Probably functions as a manganese efflux pump
Axylo_2046	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Axylo_2058	COG2321	neutral zinc metallopeptidase
Axylo_2059	COG0009	L-threonylcarbamoyladenylate synthase
Axylo_2060	COG1994	Peptidase M50
Axylo_2061	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Axylo_2062	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
Axylo_2064	COG2850	peptidyl-arginine hydroxylation
Axylo_2065	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Axylo_2069	COG0583	DNA-binding transcription factor activity
Axylo_2076	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_2077	COG0583	DNA-binding transcription factor activity
Axylo_2079	COG3360	Dodecin
Axylo_2087	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Axylo_2088	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Axylo_2096	COG0668	transmembrane transport
Axylo_2101	COG1253	flavin adenine dinucleotide binding
Axylo_2102	COG1968	undecaprenyl-diphosphatase activity
Axylo_2103	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Axylo_2104	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Axylo_2106	COG0215	cysteine-tRNA ligase activity
Axylo_2108	COG0825	malonyl-CoA metabolic process
Axylo_2109	COG0037	tRNA processing
Axylo_2110	COG0527	aspartate kinase activity
Axylo_2114	COG0784	Response regulator, receiver
Axylo_2114	COG2205	protein histidine kinase activity
Axylo_2116	COG0784	Response regulator, receiver
Axylo_2116	COG2205	protein histidine kinase activity
Axylo_2118	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
Axylo_2120	COG1309	transcriptional regulator
Axylo_2126	COG0456	acetyltransferase
Axylo_2128	COG0583	DNA-binding transcription factor activity
Axylo_2132	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Axylo_2134	COG1414	Transcriptional regulator
Axylo_2136	COG1024	Enoyl-CoA hydratase
Axylo_2137	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
Axylo_2138	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
Axylo_2140	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Axylo_2141	COG3395	kinase activity
Axylo_2143	COG1132	(ABC) transporter
Axylo_2145	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_2147	COG0318	PFAM AMP-dependent synthetase and ligase
Axylo_2150	COG0183	Belongs to the thiolase family
Axylo_2151	COG1250	3-hydroxyacyl-CoA dehydrogenase
Axylo_2151	COG1024	Enoyl-CoA hydratase
Axylo_2153	COG1024	Enoyl-CoA hydratase
Axylo_2153	COG1250	3-hydroxyacyl-CoA dehydrogenase
Axylo_2155	COG1960	acyl-CoA dehydrogenase activity
Axylo_2156	COG1309	transcriptional regulator
Axylo_2158	COG2197	response regulator
Axylo_2159	COG2197	response regulator
Axylo_2160	COG0297	glycogen (starch) synthase activity
Axylo_2161	COG0110	maltose O-acetyltransferase activity
Axylo_2162	COG0463	Glycosyl transferase, family 2
Axylo_2167	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Axylo_2171	COG1051	belongs to the nudix hydrolase family
Axylo_2172	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Axylo_2176	COG0166	Belongs to the GPI family
Axylo_2177	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Axylo_2178	COG1045	serine acetyltransferase
Axylo_2179	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Axylo_2180	COG0483	inositol monophosphate 1-phosphatase activity
Axylo_2182	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Axylo_2186	COG0598	Magnesium transport protein CorA
Axylo_2190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Axylo_2191	COG4172	Belongs to the ABC transporter superfamily
Axylo_2192	COG1846	Transcriptional regulator
Axylo_2201	COG4964	Belongs to the GSP D family
Axylo_2212	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Axylo_2215	COG3384	dioxygenase
Axylo_2216	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
Axylo_2216	COG2885	chlorophyll binding
Axylo_2217	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Axylo_2219	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_2220	COG0318	PFAM AMP-dependent synthetase and ligase
Axylo_2226	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_2227	COG3321	synthase
Axylo_2227	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_2227	COG0604	alcohol dehydrogenase
Axylo_2228	COG0410	ABC transporter
Axylo_2230	COG0559	Belongs to the binding-protein-dependent transport system permease family
Axylo_2232	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_2234	COG3246	L-lysine catabolic process to acetate
Axylo_2235	COG0371	Dehydrogenase
Axylo_2236	COG1802	Transcriptional regulator
Axylo_2237	COG3959	Transketolase, thiamine diphosphate binding domain
Axylo_2238	COG3958	Transketolase
Axylo_2239	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Axylo_2241	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_2242	COG0179	Fumarylacetoacetate (FAA) hydrolase
Axylo_2243	COG1414	Transcriptional regulator
Axylo_2249	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_2255	COG0625	glutathione transferase activity
Axylo_2258	COG3530	Putative quorum-sensing-regulated virulence factor
Axylo_2260	COG2814	Major facilitator Superfamily
Axylo_2267	COG0443	Heat shock 70 kDa protein
Axylo_2268	COG0494	nUDIX hydrolase
Axylo_2270	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Axylo_2271	COG0477	Major facilitator Superfamily
Axylo_2273	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Axylo_2275	COG0542	response to heat
Axylo_2280	COG5441	Belongs to the UPF0261 family
Axylo_2281	COG5564	TIM-barrel signal transduction protein
Axylo_2284	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
Axylo_2287	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Axylo_2289	COG1562	ergosterol biosynthetic process
Axylo_2291	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Axylo_2292	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_2294	COG3971	2-oxopent-4-enoate hydratase activity
Axylo_2297	COG1012	belongs to the aldehyde dehydrogenase family
Axylo_2298	COG3384	dioxygenase
Axylo_2304	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Axylo_2306	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_2308	COG2186	Transcriptional regulator
Axylo_2309	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
Axylo_2310	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_2312	COG0019	diaminopimelate decarboxylase activity
Axylo_2313	COG0583	DNA-binding transcription factor activity
Axylo_2314	COG0268	Binds directly to 16S ribosomal RNA
Axylo_2316	COG0728	peptidoglycan biosynthetic process
Axylo_2318	COG0563	adenylate kinase activity
Axylo_2319	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
Axylo_2320	COG2835	tetraacyldisaccharide 4'-kinase activity
Axylo_2322	COG1663	tetraacyldisaccharide 4'-kinase activity
Axylo_2324	COG0811	peptide transport
Axylo_2325	COG1570	exodeoxyribonuclease VII activity
Axylo_2327	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Axylo_2329	COG0038	chloride channel
Axylo_2330	COG0183	Belongs to the thiolase family
Axylo_2332	COG1278	Cold shock
Axylo_2333	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Axylo_2334	COG2373	Large extracellular alpha-helical protein
Axylo_2335	COG4953	penicillin-binding protein 1C
Axylo_2336	COG0542	response to heat
Axylo_2337	COG2995	paraquat-inducible protein a
Axylo_2338	COG3008	intermembrane lipid transfer
Axylo_2340	COG0506	proline dehydrogenase activity
Axylo_2340	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
Axylo_2340	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
Axylo_2342	COG0559	Belongs to the binding-protein-dependent transport system permease family
Axylo_2344	COG0411	ABC transporter
Axylo_2347	COG2271	Major facilitator Superfamily
Axylo_2355	COG1914	H( )-stimulated, divalent metal cation uptake system
Axylo_2356	COG1764	response to oxidative stress
Axylo_2359	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Axylo_2360	COG0765	amino acid transport
Axylo_2361	COG0765	amino acid transport
Axylo_2362	COG1126	abc transporter atp-binding protein
Axylo_2363	COG1902	pentaerythritol trinitrate reductase activity
Axylo_2373	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Axylo_2374	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Axylo_2375	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Axylo_2376	COG0196	riboflavin kinase activity
Axylo_2377	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Axylo_2378	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Axylo_2378	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Axylo_2381	COG0210	DNA helicase
Axylo_2383	COG1858	cytochrome C peroxidase
Axylo_2384	COG4771	TonB-dependent receptor
Axylo_2385	COG4771	TonB-dependent receptor
Axylo_2388	COG0488	(ABC) transporter
Axylo_2389	COG2890	protein-(glutamine-N5) methyltransferase activity
Axylo_2391	COG2171	N-acyltransferase activity
Axylo_2399	COG2271	Major facilitator Superfamily
Axylo_2400	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Axylo_2402	COG0277	FAD linked oxidase domain protein
Axylo_2404	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Axylo_2407	COG2877	3-deoxy-8-phosphooctulonate synthase activity
Axylo_2415	COG0583	DNA-binding transcription factor activity
Axylo_2417	COG0251	oxidation-reduction process
Axylo_2422	COG1278	Cold shock
Axylo_2424	COG1278	Cold shock
Axylo_2426	COG0501	Belongs to the peptidase M48B family
Axylo_2427	COG0544	peptidyl-prolyl cis-trans isomerase activity
Axylo_2428	COG0740	serine-type endopeptidase activity
Axylo_2429	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Axylo_2430	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Axylo_2431	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Axylo_2433	COG0556	nucleotide-excision repair
Axylo_2434	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Axylo_2436	COG1104	cysteine desulfurase activity
Axylo_2437	COG0822	iron-sulfur transferase activity
Axylo_2438	COG0316	Belongs to the HesB IscA family
Axylo_2439	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
Axylo_2440	COG0443	Heat shock 70 kDa protein
Axylo_2441	COG0633	Ferredoxin
Axylo_2442	COG2975	iron-sulfur cluster assembly
Axylo_2443	COG1803	Methylglyoxal synthase
Axylo_2446	COG1024	Enoyl-CoA hydratase
Axylo_2451	COG0410	ABC transporter
Axylo_2452	COG1022	Amp-dependent synthetase and ligase
Axylo_2453	COG0183	Belongs to the thiolase family
Axylo_2454	COG1309	transcriptional regulator
Axylo_2455	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Axylo_2456	COG3135	benzoate transporter
Axylo_2459	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Axylo_2460	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_2461	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Axylo_2462	COG2271	Major facilitator Superfamily
Axylo_2467	COG1136	(ABC) transporter
Axylo_2468	COG0084	hydrolase, TatD family'
Axylo_2470	COG0745	RESPONSE REGULATOR receiver
Axylo_2471	COG4771	TonB-dependent receptor
Axylo_2472	COG4607	ABC-type enterochelin transport system periplasmic component
Axylo_2473	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Axylo_2474	COG4605	iron ion homeostasis
Axylo_2475	COG4604	ABC transporter, ATP-binding protein
Axylo_2478	COG1595	DNA-templated transcription, initiation
Axylo_2484	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
Axylo_2485	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_2491	COG0459	protein refolding
Axylo_2492	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Axylo_2494	COG2249	NAD(P)H dehydrogenase (quinone) activity
Axylo_2498	COG3093	addiction module antidote protein HigA
Axylo_2502	COG0159	tryptophan synthase activity
Axylo_2504	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Axylo_2505	COG0477	Major facilitator Superfamily
Axylo_2506	COG0583	DNA-binding transcription factor activity
Axylo_2508	COG0583	DNA-binding transcription factor activity
Axylo_2510	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Axylo_2514	COG0613	PHP domain protein
Axylo_2516	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Axylo_2517	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Axylo_2519	COG0047	phosphoribosylformylglycinamidine synthase activity
Axylo_2519	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Axylo_2523	COG0745	RESPONSE REGULATOR receiver
Axylo_2524	COG0642	Histidine kinase
Axylo_2528	COG0583	DNA-binding transcription factor activity
Axylo_2531	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Axylo_2533	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_2539	COG2205	protein histidine kinase activity
Axylo_2539	COG0784	Response regulator, receiver
Axylo_2539	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Axylo_2539	COG2198	Histidine kinase
Axylo_2545	COG1953	Uracil, thiamine, allantoin
Axylo_2547	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Axylo_2556	COG4774	siderophore transport
Axylo_2557	COG5001	Diguanylate cyclase
Axylo_2562	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Axylo_2565	COG3618	amidohydrolase
Axylo_2566	COG0583	DNA-binding transcription factor activity
Axylo_2568	COG1960	acyl-CoA dehydrogenase activity
Axylo_2570	COG1024	Enoyl-CoA hydratase
Axylo_2576	COG0583	DNA-binding transcription factor activity
Axylo_2581	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Axylo_2585	COG4774	siderophore transport
Axylo_2592	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_2593	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
Axylo_2594	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_2595	COG0583	DNA-binding transcription factor activity
Axylo_2598	COG0747	negative chemotaxis
Axylo_2599	COG4608	Belongs to the ABC transporter superfamily
Axylo_2601	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Axylo_2602	COG0601	transmembrane transport
Axylo_2603	COG2072	flavoprotein involved in K transport
Axylo_2609	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_2610	COG3048	D-serine ammonia-lyase activity
Axylo_2611	COG0583	DNA-binding transcription factor activity
Axylo_2616	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Axylo_2618	COG0583	DNA-binding transcription factor activity
Axylo_2624	COG0519	Catalyzes the synthesis of GMP from XMP
Axylo_2624	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Axylo_2626	COG1002	Type II restriction enzyme, methylase subunits
Axylo_2628	COG0640	Transcriptional regulator
Axylo_2629	COG0583	DNA-binding transcription factor activity
Axylo_2630	COG1335	isochorismatase
Axylo_2636	COG2207	Transcriptional regulator
Axylo_2640	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_2646	COG0583	DNA-binding transcription factor activity
Axylo_2651	COG0477	Major facilitator Superfamily
Axylo_2658	COG0456	acetyltransferase
Axylo_2661	COG1199	ATP-dependent helicase activity
Axylo_2664	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Axylo_2666	COG0667	Aldo Keto reductase
Axylo_2668	COG0789	Transcriptional regulator
Axylo_2670	COG0587	DNA-directed DNA polymerase activity
Axylo_2674	COG0833	amino acid
Axylo_2675	COG0400	carboxylic ester hydrolase activity
Axylo_2677	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_2679	COG0028	Belongs to the TPP enzyme family
Axylo_2682	COG1566	PFAM secretion protein HlyD family protein
Axylo_2684	COG1289	transmembrane transporter activity
Axylo_2686	COG0720	synthase
Axylo_2687	COG0602	queuosine metabolic process
Axylo_2690	COG1902	pentaerythritol trinitrate reductase activity
Axylo_2696	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Axylo_2699	COG0842	Transport permease protein
Axylo_2700	COG1131	(ABC) transporter
Axylo_2703	COG2130	NADP-dependent
Axylo_2708	COG3842	ATPase activity
Axylo_2709	COG3842	ATPase activity
Axylo_2711	COG0395	ABC-type sugar transport system, permease component
Axylo_2718	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Axylo_2723	COG3634	alkyl hydroperoxide reductase activity
Axylo_2724	COG1959	2 iron, 2 sulfur cluster binding
Axylo_2725	COG1960	acyl-CoA dehydrogenase activity
Axylo_2733	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Axylo_2734	COG0420	3'-5' exonuclease activity
Axylo_2739	COG2111	Na H antiporter
Axylo_2739	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Axylo_2740	COG1006	Multisubunit Na H antiporter MnhC subunit
Axylo_2741	COG0651	ATP synthesis coupled electron transport
Axylo_2742	COG1863	multisubunit Na H antiporter MnhE subunit
Axylo_2743	COG2212	antiporter activity
Axylo_2744	COG1320	monovalent cation:proton antiporter activity
Axylo_2747	COG0590	tRNA wobble adenosine to inosine editing
Axylo_2748	COG1619	proteins homologs of microcin C7 resistance protein MccF
Axylo_2752	COG0488	(ABC) transporter
Axylo_2753	COG2814	Major facilitator Superfamily
Axylo_2754	COG1116	anion transmembrane transporter activity
Axylo_2759	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Axylo_2760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Axylo_2762	COG2252	PERMEase
Axylo_2763	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Axylo_2764	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Axylo_2765	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Axylo_2766	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Axylo_2771	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Axylo_2772	COG0789	Transcriptional regulator
Axylo_2775	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Axylo_2775	COG0678	peroxiredoxin activity
Axylo_2777	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
Axylo_2778	COG0584	glycerophosphoryl diester phosphodiesterase
Axylo_2780	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Axylo_2782	COG4181	ATPase activity
Axylo_2784	COG1178	ABC-type Fe3 transport system permease component
Axylo_2785	COG3842	ATPase activity
Axylo_2786	COG0583	DNA-binding transcription factor activity
Axylo_2787	COG0560	Phosphoserine phosphatase
Axylo_2790	COG0583	DNA-binding transcription factor activity
Axylo_2793	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Axylo_2796	COG0583	DNA-binding transcription factor activity
Axylo_2797	COG4336	lyase activity
Axylo_2799	COG0559	Belongs to the binding-protein-dependent transport system permease family
Axylo_2801	COG0411	ABC transporter
Axylo_2802	COG0410	ABC transporter
Axylo_2803	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Axylo_2807	COG2816	NAD+ diphosphatase activity
Axylo_2812	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Axylo_2813	COG0765	amino acid transport
Axylo_2814	COG1126	abc transporter atp-binding protein
Axylo_2816	COG1758	RNA polymerase activity
Axylo_2817	COG0194	GDP metabolic process
Axylo_2818	COG3258	Cytochrome c
Axylo_2819	COG2863	cytochrome
Axylo_2820	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_2821	COG2831	hemolysin activation secretion protein
Axylo_2822	COG3210	domain, Protein
Axylo_2824	COG0791	NLP P60 protein
Axylo_2827	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
Axylo_2828	COG0833	amino acid
Axylo_2829	COG1561	YicC-like family, N-terminal region
Axylo_2830	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Axylo_2832	COG1960	acyl-CoA dehydrogenase activity
Axylo_2833	COG0840	transmembrane signaling receptor activity
Axylo_2835	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Axylo_2836	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Axylo_2838	COG3852	Histidine kinase
Axylo_2839	COG2204	response regulator
Axylo_2840	COG0583	DNA-binding transcription factor activity
Axylo_2841	COG1741	Belongs to the pirin family
Axylo_2842	COG1741	Belongs to the pirin family
Axylo_2843	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Axylo_2844	COG1690	Belongs to the RtcB family
Axylo_2845	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_2847	COG4149	molybdate abc transporter
Axylo_2848	COG1840	ABC-type Fe3 transport system, periplasmic component
Axylo_2850	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_2853	COG0583	DNA-binding transcription factor activity
Axylo_2857	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Axylo_2859	COG0783	Belongs to the Dps family
Axylo_2861	COG0457	Tetratricopeptide repeat
Axylo_2862	COG0438	transferase activity, transferring glycosyl groups
Axylo_2867	COG1560	Kdo2-lipid A biosynthetic process
Axylo_2867	COG4783	chaperone-mediated protein folding
Axylo_2868	COG3866	Pectate lyase
Axylo_2871	COG0745	RESPONSE REGULATOR receiver
Axylo_2872	COG2205	protein histidine kinase activity
Axylo_2875	COG3842	ATPase activity
Axylo_2876	COG0395	ABC-type sugar transport system, permease component
Axylo_2877	COG1175	transmembrane transport
Axylo_2878	COG1653	transport
Axylo_2880	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
Axylo_2882	COG0559	Belongs to the binding-protein-dependent transport system permease family
Axylo_2885	COG0410	ABC transporter
Axylo_2888	COG1794	racemase activity, acting on amino acids and derivatives
Axylo_2889	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
Axylo_2891	COG0583	DNA-binding transcription factor activity
Axylo_2892	COG0625	glutathione transferase activity
Axylo_2893	COG2133	pyrroloquinoline quinone binding
Axylo_2895	COG0697	spore germination
Axylo_2896	COG2363	Small membrane protein
Axylo_2900	COG0010	Belongs to the arginase family
Axylo_2901	COG1464	Belongs to the NlpA lipoprotein family
Axylo_2902	COG3706	GGDEF domain
Axylo_2903	COG2814	Major facilitator Superfamily
Axylo_2905	COG1408	metallophosphoesterase
Axylo_2911	COG0688	phosphatidylethanolamine metabolic process
Axylo_2913	COG0488	(ABC) transporter
Axylo_2918	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Axylo_2919	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Axylo_2920	COG5001	Diguanylate cyclase
Axylo_2920	COG3300	MHYT domain
Axylo_2923	COG2814	Major facilitator Superfamily
Axylo_2929	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
Axylo_2930	COG2204	response regulator
Axylo_2937	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_2941	COG0693	protein deglycase activity
Axylo_2945	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Axylo_2947	COG1289	transmembrane transporter activity
Axylo_2948	COG5001	Diguanylate cyclase
Axylo_2948	COG3300	MHYT domain
Axylo_2960	COG1253	flavin adenine dinucleotide binding
Axylo_2962	COG2205	protein histidine kinase activity
Axylo_2974	COG3706	GGDEF domain
Axylo_2975	COG0789	Transcriptional regulator
Axylo_2977	COG3706	GGDEF domain
Axylo_2986	COG0628	permease
Axylo_2991	COG0531	amino acid
Axylo_2993	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
Axylo_2994	COG4608	Belongs to the ABC transporter superfamily
Axylo_2995	COG0444	Belongs to the ABC transporter superfamily
Axylo_2997	COG0601	transmembrane transport
Axylo_2998	COG0747	negative chemotaxis
Axylo_3000	COG0251	oxidation-reduction process
Axylo_3005	COG0179	Fumarylacetoacetate (FAA) hydrolase
Axylo_3008	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
Axylo_3013	COG3971	2-oxopent-4-enoate hydratase activity
Axylo_3019	COG0625	glutathione transferase activity
Axylo_3022	COG0477	Major facilitator Superfamily
Axylo_3024	COG0579	oxidoreductase
Axylo_3027	COG1280	lysine exporter protein (LysE YggA)
Axylo_3032	COG0071	Belongs to the small heat shock protein (HSP20) family
Axylo_3039	COG1914	H( )-stimulated, divalent metal cation uptake system
Axylo_3040	COG0589	response to stress
Axylo_3043	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Axylo_3047	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
Axylo_3048	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Axylo_3049	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
Axylo_3051	COG0589	response to stress
Axylo_3053	COG0589	response to stress
Axylo_3058	COG1210	Utp--glucose-1-phosphate uridylyltransferase
Axylo_3069	COG2192	nodulation
Axylo_3071	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
Axylo_3072	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_3073	COG0438	transferase activity, transferring glycosyl groups
Axylo_3075	COG5265	(ABC) transporter
Axylo_3077	COG1215	transferase activity, transferring glycosyl groups
Axylo_3079	COG0668	transmembrane transport
Axylo_3081	COG0166	Belongs to the GPI family
Axylo_3083	COG3685	Protein conserved in bacteria
Axylo_3087	COG0387	Pfam Sodium calcium exchanger
Axylo_3088	COG3568	Endonuclease Exonuclease Phosphatase
Axylo_3089	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Axylo_3090	COG0392	lysyltransferase activity
Axylo_3091	COG0297	glycogen (starch) synthase activity
Axylo_3092	COG0366	Alpha amylase catalytic
Axylo_3093	COG0366	Alpha amylase catalytic
Axylo_3094	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Axylo_3096	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Axylo_3097	COG1640	4-alpha-glucanotransferase
Axylo_3099	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
Axylo_3103	COG1126	abc transporter atp-binding protein
Axylo_3104	COG0765	amino acid transport
Axylo_3105	COG4597	amino acid ABC transporter
Axylo_3106	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Axylo_3107	COG0626	cystathionine gamma-synthase activity
Axylo_3108	COG0583	DNA-binding transcription factor activity
Axylo_3109	COG4771	TonB-dependent receptor
Axylo_3111	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
Axylo_3114	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Axylo_3115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Axylo_3118	COG0519	Catalyzes the synthesis of GMP from XMP
Axylo_3118	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Axylo_3120	COG1276	copper resistance
Axylo_3121	COG2372	response to copper ion
Axylo_3124	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_3125	COG2721	sulfolactate sulfo-lyase activity
Axylo_3129	COG2188	Transcriptional regulator
Axylo_3130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Axylo_3132	COG4597	amino acid ABC transporter
Axylo_3133	COG0765	amino acid transport
Axylo_3134	COG1126	abc transporter atp-binding protein
Axylo_3137	COG0745	RESPONSE REGULATOR receiver
Axylo_3139	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Axylo_3140	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
Axylo_3141	COG1120	ATPase activity
Axylo_3142	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Axylo_3145	COG0586	Pfam SNARE associated Golgi protein
Axylo_3146	COG0390	transport system, permease component
Axylo_3147	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
Axylo_3148	COG3486	L-lysine 6-monooxygenase (NADPH) activity
Axylo_3156	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Axylo_3157	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Axylo_3158	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Axylo_3161	COG0765	amino acid transport
Axylo_3163	COG2070	2-Nitropropane dioxygenase
Axylo_3164	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Axylo_3166	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Axylo_3172	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Axylo_3173	COG0583	DNA-binding transcription factor activity
Axylo_3176	COG4191	Histidine kinase
Axylo_3177	COG4566	intracellular signal transduction
Axylo_3182	COG4774	siderophore transport
Axylo_3188	COG0583	DNA-binding transcription factor activity
Axylo_3194	COG0765	amino acid transport
Axylo_3196	COG0277	FAD linked oxidase domain protein
Axylo_3201	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
Axylo_3207	COG0251	oxidation-reduction process
Axylo_3214	COG4948	Mandelate Racemase Muconate Lactonizing
Axylo_3216	COG1802	Transcriptional regulator
Axylo_3217	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Axylo_3220	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Axylo_3225	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Axylo_3226	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Axylo_3227	COG1116	anion transmembrane transporter activity
Axylo_3234	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Axylo_3235	COG4597	amino acid ABC transporter
Axylo_3239	COG2197	response regulator
Axylo_3240	COG3850	Histidine kinase
Axylo_3241	COG1763	Mo-molybdopterin cofactor biosynthetic process
Axylo_3242	COG0288	reversible hydration of carbon dioxide
Axylo_3243	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Axylo_3244	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Axylo_3245	COG2181	nitrate reductase activity
Axylo_3246	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
Axylo_3247	COG1140	nitrate reductase beta subunit
Axylo_3248	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
Axylo_3249	COG2223	nitrite transmembrane transporter activity
Axylo_3254	COG0583	DNA-binding transcription factor activity
Axylo_3256	COG0583	DNA-binding transcription factor activity
Axylo_3258	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_3264	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Axylo_3268	COG2070	2-Nitropropane dioxygenase
Axylo_3269	COG5002	protein histidine kinase activity
Axylo_3270	COG0745	RESPONSE REGULATOR receiver
Axylo_3271	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
Axylo_3272	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Axylo_3274	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Axylo_3275	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Axylo_3278	COG0783	Belongs to the Dps family
Axylo_3282	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Axylo_3283	COG0697	spore germination
Axylo_3284	COG2879	small protein
Axylo_3285	COG1966	Carbon starvation protein
Axylo_3289	COG0697	spore germination
Axylo_3290	COG0583	DNA-binding transcription factor activity
Axylo_3291	COG4521	taurine ABC transporter
Axylo_3292	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
Axylo_3293	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Axylo_3299	COG0523	cobalamin synthesis protein
Axylo_3300	COG1228	amidohydrolase
Axylo_3301	COG4172	Belongs to the ABC transporter superfamily
Axylo_3302	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Axylo_3303	COG0601	transmembrane transport
Axylo_3304	COG0747	negative chemotaxis
Axylo_3307	COG1414	Transcriptional regulator
Axylo_3308	COG0513	Belongs to the DEAD box helicase family
Axylo_3313	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Axylo_3315	COG0840	transmembrane signaling receptor activity
Axylo_3317	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Axylo_3323	COG2814	Major facilitator Superfamily
Axylo_3324	COG0386	Belongs to the glutathione peroxidase family
Axylo_3325	COG1522	sequence-specific DNA binding
Axylo_3327	COG0625	glutathione transferase activity
Axylo_3330	COG0095	Lipoate-protein ligase
Axylo_3334	COG0583	DNA-binding transcription factor activity
Axylo_3337	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Axylo_3339	COG0010	Belongs to the arginase family
Axylo_3340	COG1126	abc transporter atp-binding protein
Axylo_3342	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Axylo_3345	COG0084	hydrolase, TatD family'
Axylo_3346	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Axylo_3347	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Axylo_3348	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Axylo_3353	COG1250	3-hydroxyacyl-CoA dehydrogenase
Axylo_3353	COG1024	Enoyl-CoA hydratase
Axylo_3355	COG2914	Belongs to the UPF0125 (RnfH) family
Axylo_3356	COG2867	negative regulation of translational initiation
Axylo_3357	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Axylo_3358	COG3706	GGDEF domain
Axylo_3358	COG0745	RESPONSE REGULATOR receiver
Axylo_3361	COG0519	Catalyzes the synthesis of GMP from XMP
Axylo_3361	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Axylo_3362	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Axylo_3362	COG2169	Transcriptional regulator
Axylo_3364	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
Axylo_3370	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Axylo_3371	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Axylo_3372	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Axylo_3374	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Axylo_3375	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Axylo_3377	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Axylo_3378	COG0750	zinc metalloprotease
Axylo_3379	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Axylo_3381	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Axylo_3382	COG0233	cytoplasmic translational termination
Axylo_3383	COG0528	UMP kinase activity
Axylo_3384	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Axylo_3385	COG0052	Belongs to the universal ribosomal protein uS2 family
Axylo_3386	COG0024	Methionine aminopeptidase
Axylo_3387	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
Axylo_3389	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
Axylo_3391	COG1451	nucleotide metabolic process
Axylo_3393	COG1286	toxin biosynthetic process
Axylo_3395	COG0285	dihydrofolate synthase activity
Axylo_3397	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_3398	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Axylo_3400	COG1414	Transcriptional regulator
Axylo_3402	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
Axylo_3406	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Axylo_3408	COG1677	Flagellar hook-basal body complex protein FliE
Axylo_3409	COG1766	The M ring may be actively involved in energy transduction
Axylo_3410	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Axylo_3415	COG1580	Controls the rotational direction of flagella during chemotaxis
Axylo_3417	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Axylo_3422	COG0840	transmembrane signaling receptor activity
Axylo_3423	COG0840	transmembrane signaling receptor activity
Axylo_3425	COG0840	transmembrane signaling receptor activity
Axylo_3426	COG0840	transmembrane signaling receptor activity
Axylo_3428	COG1256	bacterial-type flagellum assembly
Axylo_3430	COG1706	bacterial-type flagellum-dependent cell motility
Axylo_3431	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
Axylo_3432	COG4786	Flagellar basal body rod
Axylo_3433	COG4787	bacterial-type flagellum-dependent cell motility
Axylo_3434	COG1749	Flagellar hook protein flgE
Axylo_3435	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
Axylo_3436	COG1558	bacterial-type flagellum-dependent cell motility
Axylo_3439	COG2747	anti-sigma28 factor FlgM
Axylo_3444	COG0840	transmembrane signaling receptor activity
Axylo_3445	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
Axylo_3446	COG0745	RESPONSE REGULATOR receiver
Axylo_3447	COG2201	protein-glutamate methylesterase activity
Axylo_3448	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Axylo_3449	COG0840	transmembrane signaling receptor activity
Axylo_3450	COG0835	chemotaxis
Axylo_3457	COG1191	sigma factor activity
Axylo_3458	COG4797	methyltransferase
Axylo_3458	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Axylo_3464	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Axylo_3465	COG0508	dehydrogenase complex catalyzes the overall conversion of
Axylo_3466	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
Axylo_3468	COG4566	intracellular signal transduction
Axylo_3470	COG0339	signal peptide processing
Axylo_3472	COG1999	signal sequence binding
Axylo_3473	COG2261	transglycosylase associated protein
Axylo_3474	COG1538	Outer membrane efflux protein
Axylo_3477	COG0583	DNA-binding transcription factor activity
Axylo_3478	COG1187	pseudouridine synthase activity
Axylo_3479	COG3161	chorismate lyase activity
Axylo_3480	COG0477	Major facilitator Superfamily
Axylo_3484	COG4681	YaeQ
Axylo_3485	COG4172	Belongs to the ABC transporter superfamily
Axylo_3487	COG0601	transmembrane transport
Axylo_3488	COG0747	negative chemotaxis
Axylo_3490	COG0583	DNA-binding transcription factor activity
Axylo_3497	COG2165	general secretion pathway protein
Axylo_3511	COG0668	transmembrane transport
Axylo_3512	COG0165	Argininosuccinate lyase
Axylo_3516	COG0022	dehydrogenase e1 component
Axylo_3518	COG4774	siderophore transport
Axylo_3523	COG0789	Transcriptional regulator
Axylo_3525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Axylo_3527	COG2271	Major facilitator Superfamily
Axylo_3529	COG0307	riboflavin synthase, alpha
Axylo_3531	COG2186	Transcriptional regulator
Axylo_3532	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_3538	COG2070	2-Nitropropane dioxygenase
Axylo_3548	COG0154	amidase activity
Axylo_3549	COG2814	Major facilitator Superfamily
Axylo_3556	COG2814	Major facilitator Superfamily
Axylo_3559	COG0583	DNA-binding transcription factor activity
Axylo_3562	COG0583	DNA-binding transcription factor activity
Axylo_3567	COG2059	Chromate
Axylo_3570	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_3574	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Axylo_3576	COG5265	(ABC) transporter
Axylo_3590	COG0477	Major facilitator Superfamily
Axylo_3599	COG2610	gluconate transmembrane transporter activity
Axylo_3600	COG0583	DNA-binding transcription factor activity
Axylo_3601	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_3602	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
Axylo_3610	COG1024	Enoyl-CoA hydratase
Axylo_3611	COG5001	Diguanylate cyclase
Axylo_3612	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_3613	COG0129	dihydroxy-acid dehydratase activity
Axylo_3615	COG0583	DNA-binding transcription factor activity
Axylo_3616	COG1250	3-hydroxyacyl-CoA dehydrogenase
Axylo_3617	COG3246	L-lysine catabolic process to acetate
Axylo_3621	COG3381	protein complex oligomerization
Axylo_3623	COG3005	denitrification pathway
Axylo_3624	COG4133	protoheme IX ABC transporter activity
Axylo_3625	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Axylo_3627	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Axylo_3628	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
Axylo_3630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Axylo_3631	COG3088	subunit of a heme lyase
Axylo_3635	COG5001	Diguanylate cyclase
Axylo_3635	COG5002	protein histidine kinase activity
Axylo_3635	COG3447	MASE1 domain protein
Axylo_3636	COG0583	DNA-binding transcription factor activity
Axylo_3641	COG4172	Belongs to the ABC transporter superfamily
Axylo_3643	COG0583	DNA-binding transcription factor activity
Axylo_3644	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_3645	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_3648	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Axylo_3650	COG1063	alcohol dehydrogenase
Axylo_3654	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Axylo_3655	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Axylo_3656	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_3657	COG2207	Transcriptional regulator
Axylo_3664	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_3665	COG3328	transposase activity
Axylo_3668	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
Axylo_3669	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Axylo_3671	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_3672	COG1024	Enoyl-CoA hydratase
Axylo_3673	COG0534	Mate efflux family protein
Axylo_3676	COG0697	spore germination
Axylo_3677	COG0697	spore germination
Axylo_3680	COG1280	lysine exporter protein (LysE YggA)
Axylo_3683	COG1280	lysine exporter protein (LysE YggA)
Axylo_3684	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
Axylo_3690	COG1960	acyl-CoA dehydrogenase activity
Axylo_3694	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
Axylo_3695	COG2814	Major facilitator Superfamily
Axylo_3698	COG0625	glutathione transferase activity
Axylo_3699	COG0583	DNA-binding transcription factor activity
Axylo_3700	COG0583	DNA-binding transcription factor activity
Axylo_3701	COG2814	Major facilitator Superfamily
Axylo_3702	COG0583	DNA-binding transcription factor activity
Axylo_3706	COG0506	proline dehydrogenase activity
Axylo_3707	COG0697	spore germination
Axylo_3708	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Axylo_3709	COG1959	2 iron, 2 sulfur cluster binding
Axylo_3710	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Axylo_3710	COG1017	nitric oxide dioxygenase activity
Axylo_3714	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Axylo_3715	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Axylo_3717	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Axylo_3725	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Axylo_3727	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_3728	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Axylo_3730	COG1610	YqeY-like protein
Axylo_3733	COG3468	outer membrane autotransporter barrel domain protein
Axylo_3733	COG3210	domain, Protein
Axylo_3738	COG0457	Tetratricopeptide repeat
Axylo_3739	COG0726	polysaccharide deacetylase
Axylo_3739	COG1649	PFAM Uncharacterised BCR, COG1649
Axylo_3740	COG1215	transferase activity, transferring glycosyl groups
Axylo_3742	COG2223	nitrite transmembrane transporter activity
Axylo_3743	COG1917	Cupin 2, conserved barrel domain protein
Axylo_3743	COG4977	sequence-specific DNA binding
Axylo_3745	COG1595	DNA-templated transcription, initiation
Axylo_3746	COG3712	iron ion homeostasis
Axylo_3747	COG4774	siderophore transport
Axylo_3748	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Axylo_3751	COG0656	L-ascorbic acid biosynthetic process
Axylo_3752	COG5265	(ABC) transporter
Axylo_3758	COG1116	anion transmembrane transporter activity
Axylo_3763	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_3764	COG0583	DNA-binding transcription factor activity
Axylo_3770	COG1522	sequence-specific DNA binding
Axylo_3780	COG0384	phenazine biosynthesis protein PhzF
Axylo_3787	COG0776	regulation of translation
Axylo_3788	COG0072	phenylalanine-tRNA ligase activity
Axylo_3788	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Axylo_3789	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Axylo_3790	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Axylo_3791	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Axylo_3793	COG2960	long-chain fatty acid transporting porin activity
Axylo_3795	COG0347	Belongs to the P(II) protein family
Axylo_3796	COG0004	ammonium transporteR
Axylo_3797	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Axylo_3798	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Axylo_3800	COG0189	ligase activity
Axylo_3801	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Axylo_3802	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Axylo_3804	COG2197	response regulator
Axylo_3805	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Axylo_3811	COG1012	belongs to the aldehyde dehydrogenase family
Axylo_3813	COG0601	transmembrane transport
Axylo_3814	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Axylo_3819	COG1609	Transcriptional regulator
Axylo_3820	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
Axylo_3821	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Axylo_3822	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Axylo_3823	COG0129	dihydroxy-acid dehydratase activity
Axylo_3824	COG0657	acetylesterase activity
Axylo_3824	COG2755	lipolytic protein G-D-S-L family
Axylo_3832	COG0135	phosphoribosylanthranilate isomerase activity
Axylo_3833	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
Axylo_3834	COG0101	tRNA pseudouridine synthase activity
Axylo_3836	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Axylo_3837	COG0473	3-isopropylmalate dehydrogenase activity
Axylo_3838	COG0066	3-isopropylmalate dehydratase activity
Axylo_3839	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Axylo_3840	COG1538	Outer membrane efflux protein
Axylo_3842	COG2274	protein secretion by the type I secretion system
Axylo_3843	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Axylo_3848	COG4783	chaperone-mediated protein folding
Axylo_3849	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Axylo_3854	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
Axylo_3856	COG1295	ribonuclease BN
Axylo_3858	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Axylo_3864	COG4964	Belongs to the GSP D family
Axylo_3870	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Axylo_3870	COG2755	lipolytic protein G-D-S-L family
Axylo_3873	COG0438	transferase activity, transferring glycosyl groups
Axylo_3879	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Axylo_3880	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
Axylo_3881	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Axylo_3882	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
Axylo_3883	COG0330	HflC and HflK could
Axylo_3884	COG0330	HflC and HflK could
Axylo_3885	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Axylo_3886	COG1923	regulation of RNA biosynthetic process
Axylo_3887	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Axylo_3888	COG1160	GTP binding
Axylo_3889	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Axylo_3890	COG2976	Protein conserved in bacteria
Axylo_3891	COG0124	histidyl-tRNA synthetase
Axylo_3892	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Axylo_3894	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Axylo_3895	COG0105	UTP biosynthetic process
Axylo_3896	COG0525	valine-tRNA ligase activity
Axylo_3897	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Axylo_3899	COG0765	amino acid transport
Axylo_3900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Axylo_3901	COG1396	sequence-specific DNA binding
Axylo_3902	COG0336	Belongs to the RNA methyltransferase TrmD family
Axylo_3903	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Axylo_3904	COG0228	four-way junction DNA binding
Axylo_3906	COG0425	Belongs to the sulfur carrier protein TusA family
Axylo_3907	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Axylo_3910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Axylo_3912	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Axylo_3913	COG2076	Multidrug Resistance protein
Axylo_3914	COG3217	Mosc domain protein beta barrel domain protein
Axylo_3914	COG0633	Ferredoxin
Axylo_3915	COG5285	phytanoyl-CoA dioxygenase
Axylo_3916	COG0662	Cupin 2, conserved barrel domain protein
Axylo_3917	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Axylo_3921	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Axylo_3922	COG2311	Membrane
Axylo_3923	COG1309	transcriptional regulator
Axylo_3926	COG0187	DNA topoisomerase II activity
Axylo_3928	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Axylo_3931	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
Axylo_3932	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Axylo_3936	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Axylo_3938	COG3391	amine dehydrogenase activity
Axylo_3944	COG1846	Transcriptional regulator
Axylo_3946	COG1566	PFAM secretion protein HlyD family protein
Axylo_3947	COG2814	Major facilitator Superfamily
Axylo_3949	COG0473	3-isopropylmalate dehydrogenase activity
Axylo_3950	COG0433	COG0433 Predicted ATPase
Axylo_3951	COG0217	transcriptional regulatory protein
Axylo_3952	COG0151	Belongs to the GarS family
Axylo_3953	COG0408	coproporphyrinogen oxidase activity
Axylo_3954	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Axylo_3955	COG0799	negative regulation of ribosome biogenesis
Axylo_3956	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Axylo_3957	COG0424	maF-like protein
Axylo_3958	COG1301	dicarboxylic acid transport
Axylo_3959	COG4191	Histidine kinase
Axylo_3960	COG2204	response regulator
Axylo_3967	COG0583	DNA-binding transcription factor activity
Axylo_3968	COG0427	acetyl-CoA hydrolase
Axylo_3969	COG0583	DNA-binding transcription factor activity
Axylo_3970	COG3264	Mechanosensitive ion channel
Axylo_3970	COG1511	domain protein
Axylo_3983	COG3842	ATPase activity
Axylo_3984	COG1176	ABC-type spermidine putrescine transport system, permease component I
Axylo_3985	COG1177	transmembrane transport
Axylo_3986	COG3938	Belongs to the proline racemase family
Axylo_3988	COG0517	IMP dehydrogenase activity
Axylo_3994	COG0500	methyltransferase
Axylo_3995	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
Axylo_4000	COG0667	Aldo Keto reductase
Axylo_4001	COG2207	Transcriptional regulator
Axylo_4003	COG1595	DNA-templated transcription, initiation
Axylo_4006	COG2841	Protein conserved in bacteria
Axylo_4009	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Axylo_4010	COG0477	Major facilitator Superfamily
Axylo_4012	COG2814	Major facilitator Superfamily
Axylo_4013	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Axylo_4021	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Axylo_4023	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Axylo_4024	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
Axylo_4025	COG1534	Rna-binding protein
Axylo_4026	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Axylo_4027	COG0840	transmembrane signaling receptor activity
Axylo_4028	COG2233	PERMEase
Axylo_4030	COG1840	ABC-type Fe3 transport system, periplasmic component
Axylo_4034	COG0406	alpha-ribazole phosphatase activity
Axylo_4035	COG4221	oxidoreductase activity
Axylo_4037	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Axylo_4038	COG0505	Belongs to the CarA family
Axylo_4039	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Axylo_4042	COG0745	RESPONSE REGULATOR receiver
Axylo_4045	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Axylo_4047	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Axylo_4048	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Axylo_4049	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Axylo_4051	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Axylo_4052	COG1074	ATP-dependent DNA helicase activity
Axylo_4056	COG2070	2-Nitropropane dioxygenase
Axylo_4060	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Axylo_4061	COG1024	Enoyl-CoA hydratase
Axylo_4063	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Axylo_4064	COG0318	PFAM AMP-dependent synthetase and ligase
Axylo_4067	COG1686	Belongs to the peptidase S11 family
Axylo_4071	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Axylo_4072	COG4974	Belongs to the 'phage' integrase family
Axylo_4073	COG0583	DNA-binding transcription factor activity
Axylo_4074	COG0028	Belongs to the TPP enzyme family
Axylo_4079	COG3328	transposase activity
Axylo_4085	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Axylo_4091	COG0559	Belongs to the binding-protein-dependent transport system permease family
Axylo_4092	COG0411	ABC transporter
Axylo_4094	COG0028	Belongs to the TPP enzyme family
Axylo_4095	COG1126	abc transporter atp-binding protein
Axylo_4096	COG0765	amino acid transport
Axylo_4098	COG0010	Belongs to the arginase family
Axylo_4099	COG1414	Transcriptional regulator
Axylo_4100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Axylo_4103	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
Axylo_4104	COG1414	Transcriptional regulator
Axylo_4105	COG0009	L-threonylcarbamoyladenylate synthase
Axylo_4106	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Axylo_4107	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Axylo_4108	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
Axylo_4110	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Axylo_4114	COG1301	dicarboxylic acid transport
Axylo_4118	COG3454	Phosphonate metabolism
Axylo_4119	COG4778	phosphonate C-P lyase system protein PhnL
Axylo_4120	COG4107	phosphonate C-P lyase system protein PhnK
Axylo_4121	COG3627	carbon phosphorus lyase activity
Axylo_4122	COG3626	phosphonate metabolism
Axylo_4123	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
Axylo_4124	COG3624	Phosphonate C-P lyase system protein PhnG
Axylo_4125	COG2188	Transcriptional regulator
Axylo_4126	COG3454	Phosphonate metabolism
Axylo_4128	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
Axylo_4129	COG0583	DNA-binding transcription factor activity
Axylo_4133	COG3639	organic phosphonate transmembrane transporter activity
Axylo_4135	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
Axylo_4137	COG0640	Transcriptional regulator
Axylo_4139	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Axylo_4141	COG0739	heme binding
Axylo_4143	COG0521	Mo-molybdopterin cofactor biosynthetic process
Axylo_4146	COG0306	phosphate transporter
Axylo_4153	COG0625	glutathione transferase activity
Axylo_4157	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
Axylo_4158	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Axylo_4161	COG0126	phosphoglycerate kinase activity
Axylo_4162	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Axylo_4163	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
Axylo_4165	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Axylo_4166	COG2732	(Barnase) inhibitor
Axylo_4168	COG0281	malic enzyme
Axylo_4168	COG0280	phosphate acetyltransferase
Axylo_4170	COG0436	Aminotransferase
Axylo_4172	COG0741	lytic transglycosylase activity
Axylo_4173	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Axylo_4176	COG4575	ribosome binding
Axylo_4178	COG1116	anion transmembrane transporter activity
Axylo_4179	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Axylo_4180	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Axylo_4181	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Axylo_4181	COG1648	precorrin-2 dehydrogenase activity
Axylo_4182	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Axylo_4183	COG2027	D-alanyl-D-alanine carboxypeptidase
Axylo_4186	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Axylo_4188	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Axylo_4189	COG0343	queuine tRNA-ribosyltransferase activity
Axylo_4191	COG3077	Addiction module antitoxin, RelB DinJ family
Axylo_4192	COG1862	Preprotein translocase
Axylo_4193	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Axylo_4194	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Axylo_4196	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Axylo_4198	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Axylo_4199	COG1702	phosphate starvation-inducible protein PhoH
Axylo_4200	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Axylo_4201	COG4535	Mg2 and Co2 transporter CorC
Axylo_4202	COG0815	Transfers the fatty acyl group on membrane lipoproteins
Axylo_4203	COG0667	Aldo Keto reductase
Axylo_4211	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Axylo_4212	COG0697	spore germination
Axylo_4214	COG0678	peroxiredoxin activity
Axylo_4216	COG0412	Dienelactone hydrolase
Axylo_4218	COG0315	cyclic pyranopterin monophosphate synthase activity
Axylo_4220	COG0314	molybdopterin synthase activity
Axylo_4221	COG0521	Mo-molybdopterin cofactor biosynthetic process
Axylo_4222	COG0303	'Molybdopterin
Axylo_4224	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Axylo_4228	COG3383	formate dehydrogenase (NAD+) activity
Axylo_4229	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Axylo_4236	COG0583	DNA-binding transcription factor activity
Axylo_4237	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
Axylo_4240	COG2205	protein histidine kinase activity
Axylo_4241	COG0745	RESPONSE REGULATOR receiver
Axylo_4244	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Axylo_4247	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_4251	COG2828	Protein conserved in bacteria
Axylo_4252	COG0583	DNA-binding transcription factor activity
Axylo_4253	COG0456	acetyltransferase
Axylo_4255	COG1595	DNA-templated transcription, initiation
Axylo_4262	COG0559	Belongs to the binding-protein-dependent transport system permease family
Axylo_4264	COG0411	ABC transporter
Axylo_4265	COG0410	ABC transporter
Axylo_4267	COG4774	siderophore transport
Axylo_4270	COG0671	phosphoesterase, PA-phosphatase related
Axylo_4271	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Axylo_4273	COG1666	GTP binding
Axylo_4274	COG1120	ATPase activity
Axylo_4275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Axylo_4276	COG4558	Periplasmic binding protein
Axylo_4277	COG3720	iron ion transport
Axylo_4279	COG3712	iron ion homeostasis
Axylo_4280	COG1595	DNA-templated transcription, initiation
Axylo_4286	COG2378	regulation of single-species biofilm formation
Axylo_4292	COG1113	amino acid transport
Axylo_4294	COG1522	sequence-specific DNA binding
Axylo_4295	COG1272	protein, Hemolysin III
Axylo_4296	COG3191	aminopeptidase activity
Axylo_4297	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Axylo_4298	COG0765	amino acid transport
Axylo_4305	COG1999	signal sequence binding
Axylo_4309	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
Axylo_4311	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Axylo_4312	COG1845	cytochrome c oxidase, subunit III
Axylo_4313	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
Axylo_4318	COG4772	TonB-dependent receptor
Axylo_4322	COG0280	phosphate acetyltransferase
Axylo_4322	COG0281	malic enzyme
Axylo_4325	COG0697	spore germination
Axylo_4332	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_4334	COG0583	DNA-binding transcription factor activity
Axylo_4337	COG0456	acetyltransferase
Axylo_4339	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Axylo_4341	COG3145	DNA-N1-methyladenine dioxygenase activity
Axylo_4342	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Axylo_4345	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
Axylo_4346	COG1285	pathogenesis
Axylo_4347	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_4348	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Axylo_4349	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
Axylo_4351	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Axylo_4354	COG3712	iron ion homeostasis
Axylo_4357	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
Axylo_4358	COG0330	HflC and HflK could
Axylo_4364	COG2807	transmembrane transport
Axylo_4365	COG2207	Transcriptional regulator
Axylo_4366	COG4106	trans-aconitate 2-methyltransferase activity
Axylo_4370	COG0583	DNA-binding transcription factor activity
Axylo_4378	COG0477	Major facilitator Superfamily
Axylo_4379	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Axylo_4380	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Axylo_4381	COG1845	cytochrome c oxidase, subunit III
Axylo_4382	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
Axylo_4384	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Axylo_4385	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Axylo_4387	COG2814	Major facilitator Superfamily
Axylo_4389	COG0625	glutathione transferase activity
Axylo_4394	COG2197	response regulator
Axylo_4399	COG3707	response regulator
Axylo_4400	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Axylo_4400	COG2146	nitrite reductase [NAD(P)H] activity
Axylo_4401	COG2146	nitrite reductase [NAD(P)H] activity
Axylo_4401	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Axylo_4402	COG0243	molybdopterin cofactor binding
Axylo_4403	COG0667	Aldo Keto reductase
Axylo_4404	COG0656	L-ascorbic acid biosynthetic process
Axylo_4405	COG0583	DNA-binding transcription factor activity
Axylo_4406	COG0023	Translation Initiation Factor
Axylo_4408	COG0456	acetyltransferase
Axylo_4408	COG0454	-acetyltransferase
Axylo_4413	COG0840	transmembrane signaling receptor activity
Axylo_4414	COG2199	diguanylate cyclase activity
Axylo_4414	COG2203	Gaf domain
Axylo_4415	COG0640	Transcriptional regulator
Axylo_4417	COG0740	serine-type endopeptidase activity
Axylo_4422	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Axylo_4424	COG0596	Alpha beta hydrolase
Axylo_4433	COG0028	Belongs to the TPP enzyme family
Axylo_4440	COG4771	TonB-dependent receptor
Axylo_4445	COG1201	RNA secondary structure unwinding
Axylo_4446	COG1793	dna ligase
Axylo_4449	COG0798	PFAM Bile acid sodium symporter
Axylo_4450	COG1393	Belongs to the ArsC family
Axylo_4451	COG0431	NADPH-dependent FMN reductase
Axylo_4455	COG0697	spore germination
Axylo_4461	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Axylo_4469	COG0745	RESPONSE REGULATOR receiver
Axylo_4471	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Axylo_4476	COG0793	Belongs to the peptidase S41A family
Axylo_4485	COG2200	EAL domain
Axylo_4490	COG4191	Histidine kinase
Axylo_4493	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_4496	COG1686	Belongs to the peptidase S11 family
Axylo_4504	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Axylo_4505	COG0459	protein refolding
Axylo_4506	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Axylo_4507	COG0583	DNA-binding transcription factor activity
Axylo_4511	COG1176	ABC-type spermidine putrescine transport system, permease component I
Axylo_4513	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Axylo_4517	COG3842	ATPase activity
Axylo_4518	COG2072	flavoprotein involved in K transport
Axylo_4520	COG1846	Transcriptional regulator
Axylo_4524	COG1917	Cupin 2, conserved barrel domain protein
Axylo_4529	COG1137	ATPase activity
Axylo_4530	COG0410	ABC transporter
Axylo_4531	COG0246	Mannitol dehydrogenase
Axylo_4532	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
Axylo_4533	COG1252	NADH dehydrogenase
Axylo_4534	COG0284	orotidine-5'-phosphate decarboxylase activity
Axylo_4535	COG1546	Belongs to the CinA family
Axylo_4536	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
Axylo_4537	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
Axylo_4538	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Axylo_4539	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Axylo_4544	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
Axylo_4545	COG3639	organic phosphonate transmembrane transporter activity
Axylo_4546	COG3639	organic phosphonate transmembrane transporter activity
Axylo_4549	COG0742	ribosomal rna small subunit methyltransferase
Axylo_4550	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Axylo_4551	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Axylo_4552	COG3135	benzoate transporter
Axylo_4555	COG2814	Major facilitator Superfamily
Axylo_4560	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
Axylo_4561	COG4804	nuclease activity
Axylo_4564	COG0012	GTP binding
Axylo_4566	COG0193	aminoacyl-tRNA hydrolase activity
Axylo_4567	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Axylo_4568	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Axylo_4570	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Axylo_4571	COG0840	transmembrane signaling receptor activity
Axylo_4574	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Axylo_4579	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
Axylo_4581	COG0204	Acyl-transferase
Axylo_4582	COG1368	sulfuric ester hydrolase activity
Axylo_4583	COG2186	Transcriptional regulator
Axylo_4584	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Axylo_4586	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
Axylo_4588	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Axylo_4590	COG2205	protein histidine kinase activity
Axylo_4591	COG0745	RESPONSE REGULATOR receiver
Axylo_4592	COG0277	FAD linked oxidase domain protein
Axylo_4595	COG0166	Belongs to the GPI family
Axylo_4596	COG0405	Gamma-glutamyltransferase
Axylo_4598	COG0438	transferase activity, transferring glycosyl groups
Axylo_4599	COG0438	transferase activity, transferring glycosyl groups
Axylo_4601	COG0438	transferase activity, transferring glycosyl groups
Axylo_4604	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
Axylo_4605	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Axylo_4606	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
Axylo_4608	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
Axylo_4611	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Axylo_4615	COG0747	negative chemotaxis
Axylo_4616	COG0601	transmembrane transport
Axylo_4617	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Axylo_4618	COG4172	Belongs to the ABC transporter superfamily
Axylo_4619	COG0154	amidase activity
Axylo_4622	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Axylo_4622	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Axylo_4623	COG0509	glycine decarboxylation via glycine cleavage system
Axylo_4624	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Axylo_4627	COG2081	HI0933 family
Axylo_4628	COG1982	Orn Lys Arg decarboxylase major
Axylo_4631	COG3706	GGDEF domain
Axylo_4633	COG0717	Belongs to the dCTP deaminase family
Axylo_4636	COG0489	protein tyrosine kinase activity
Axylo_4638	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Axylo_4638	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Axylo_4644	COG0745	RESPONSE REGULATOR receiver
Axylo_4645	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Axylo_4650	COG2200	EAL domain
Axylo_4654	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Axylo_4655	COG0842	Transport permease protein
Axylo_4655	COG1129	ABC transporter
Axylo_4656	COG0842	Transport permease protein
Axylo_4658	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_4659	COG1271	oxidase subunit
Axylo_4660	COG1294	oxidase, subunit
Axylo_4662	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Axylo_4668	COG0583	DNA-binding transcription factor activity
Axylo_4669	COG3258	Cytochrome c
Axylo_4671	COG0625	glutathione transferase activity
Axylo_4672	COG0477	Major facilitator Superfamily
Axylo_4675	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Axylo_4683	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Axylo_4686	COG2828	Protein conserved in bacteria
Axylo_4688	COG0165	Argininosuccinate lyase
Axylo_4689	COG2205	protein histidine kinase activity
Axylo_4690	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_4691	COG3246	L-lysine catabolic process to acetate
Axylo_4695	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Axylo_4700	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Axylo_4701	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Axylo_4702	COG0583	DNA-binding transcription factor activity
Axylo_4703	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Axylo_4706	COG1652	LysM domain
Axylo_4707	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Axylo_4708	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Axylo_4711	COG0625	glutathione transferase activity
Axylo_4714	COG1012	belongs to the aldehyde dehydrogenase family
Axylo_4722	COG3550	peptidyl-serine autophosphorylation
Axylo_4726	COG1414	Transcriptional regulator
Axylo_4727	COG3734	2-keto-3-deoxy-galactonokinase
Axylo_4728	COG0800	Aldolase
Axylo_4729	COG4948	Mandelate Racemase Muconate Lactonizing
Axylo_4730	COG2271	Major facilitator Superfamily
Axylo_4731	COG1131	(ABC) transporter
Axylo_4736	COG2814	Major facilitator Superfamily
Axylo_4738	COG1396	sequence-specific DNA binding
Axylo_4739	COG0326	Molecular chaperone. Has ATPase activity
Axylo_4741	COG2233	PERMEase
Axylo_4748	COG4372	Transposase
Axylo_4750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Axylo_4751	COG0501	Belongs to the peptidase M48B family
Axylo_4760	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Axylo_4764	COG0071	Belongs to the small heat shock protein (HSP20) family
Axylo_4770	COG4638	Rieske (2fe-2S)
Axylo_4781	COG3657	addiction module killer protein
Axylo_4784	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Axylo_4785	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Axylo_4788	COG1172	Belongs to the binding-protein-dependent transport system permease family
Axylo_4789	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Axylo_4790	COG3246	L-lysine catabolic process to acetate
Axylo_4793	COG0583	DNA-binding transcription factor activity
Axylo_4815	COG5002	protein histidine kinase activity
Axylo_4815	COG2198	Histidine kinase
Axylo_4815	COG0784	Response regulator, receiver
Axylo_4816	COG0745	RESPONSE REGULATOR receiver
Axylo_4821	COG0583	DNA-binding transcription factor activity
Axylo_4823	COG1695	Transcriptional regulator
Axylo_4826	COG0477	Major facilitator Superfamily
Axylo_4829	COG0277	FAD linked oxidase domain protein
Axylo_4831	COG3842	ATPase activity
Axylo_4832	COG1176	ABC-type spermidine putrescine transport system, permease component I
Axylo_4836	COG0628	permease
Axylo_4837	COG0583	DNA-binding transcription factor activity
Axylo_4838	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Axylo_4848	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
Axylo_4850	COG2186	Transcriptional regulator
Axylo_4852	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Axylo_4854	COG0559	Belongs to the binding-protein-dependent transport system permease family
Axylo_4856	COG0411	ABC transporter
Axylo_4857	COG0410	ABC transporter
Axylo_4858	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_4859	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Axylo_4861	COG0508	dehydrogenase complex catalyzes the overall conversion of
Axylo_4862	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Axylo_4863	COG0583	DNA-binding transcription factor activity
Axylo_4864	COG0129	dihydroxy-acid dehydratase activity
Axylo_4866	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Axylo_4867	COG0583	DNA-binding transcription factor activity
Axylo_4870	COG2200	EAL domain
Axylo_4871	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Axylo_4872	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
Axylo_4873	COG1250	3-hydroxyacyl-CoA dehydrogenase
Axylo_4874	COG2031	fatty acid transporter
Axylo_4875	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_4876	COG1414	Transcriptional regulator
Axylo_4878	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
Axylo_4881	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Axylo_4885	COG0288	reversible hydration of carbon dioxide
Axylo_4887	COG2801	Transposase and inactivated derivatives
Axylo_4888	COG1802	Transcriptional regulator
Axylo_4889	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_4891	COG0559	Belongs to the binding-protein-dependent transport system permease family
Axylo_4895	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_4898	COG0625	glutathione transferase activity
Axylo_4902	COG0583	DNA-binding transcription factor activity
Axylo_4904	COG0583	DNA-binding transcription factor activity
Axylo_4905	COG0477	Major facilitator Superfamily
Axylo_4910	COG0318	PFAM AMP-dependent synthetase and ligase
Axylo_4914	COG1464	Belongs to the NlpA lipoprotein family
Axylo_4917	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
Axylo_4918	COG2890	protein-(glutamine-N5) methyltransferase activity
Axylo_4919	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Axylo_4920	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Axylo_4922	COG1280	lysine exporter protein (LysE YggA)
Axylo_4923	COG1522	sequence-specific DNA binding
Axylo_4927	COG3622	Belongs to the hyi family
Axylo_4930	COG0477	Major facilitator Superfamily
Axylo_4932	COG2186	Transcriptional regulator
Axylo_4933	COG3395	kinase activity
Axylo_4934	COG2084	Dehydrogenase
Axylo_4935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Axylo_4936	COG3622	Belongs to the hyi family
Axylo_4937	COG0235	Class ii aldolase
Axylo_4944	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Axylo_4948	COG0142	geranyltranstransferase activity
Axylo_4949	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Axylo_4950	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Axylo_4951	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Axylo_4952	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Axylo_4955	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Axylo_4955	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Axylo_4956	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Axylo_4958	COG2186	Transcriptional regulator
Axylo_4959	COG5002	protein histidine kinase activity
Axylo_4959	COG5001	Diguanylate cyclase
Axylo_4959	COG3447	MASE1 domain protein
Axylo_4960	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Axylo_4961	COG0793	Belongs to the peptidase S41A family
Axylo_4962	COG4942	peptidase
Axylo_4963	COG0588	phosphoglycerate mutase activity
Axylo_4965	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Axylo_4966	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
Axylo_4967	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Axylo_4971	COG2226	methyltransferase
Axylo_4972	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
Axylo_4973	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Axylo_4974	COG0569	domain protein
Axylo_4975	COG2204	response regulator
Axylo_4976	COG5000	phosphorelay sensor kinase activity
Axylo_4978	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Axylo_4978	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Axylo_4979	COG1280	lysine exporter protein (LysE YggA)
Axylo_4981	COG2076	Multidrug Resistance protein
Axylo_4982	COG1733	regulation of RNA biosynthetic process
Axylo_4986	COG0546	phosphoglycolate phosphatase activity
Axylo_4988	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Axylo_4989	COG0242	peptide deformylase activity
Axylo_4990	COG0758	DNA mediated transformation
Axylo_4993	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Axylo_4994	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Axylo_4995	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Axylo_4996	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_4999	COG1238	metal cluster binding
Axylo_5000	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Axylo_5001	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
Axylo_5004	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Axylo_5005	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
Axylo_5006	COG4988	ABC transporter
Axylo_5008	COG1294	oxidase, subunit
Axylo_5011	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
Axylo_5013	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
Axylo_5016	COG1137	ATPase activity
Axylo_5017	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Axylo_5019	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
Axylo_5020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Axylo_5023	COG1660	Displays ATPase and GTPase activities
Axylo_5025	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Axylo_5027	COG0792	nuclease activity
Axylo_5028	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
Axylo_5030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Axylo_5032	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Axylo_5034	COG1309	transcriptional regulator
Axylo_5035	COG0471	metal ion transport
Axylo_5036	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
Axylo_5037	COG0772	Belongs to the SEDS family
Axylo_5038	COG0768	penicillin binding
Axylo_5040	COG1792	Involved in formation and maintenance of cell shape
Axylo_5041	COG1077	Cell shape determining protein MreB Mrl
Axylo_5042	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Axylo_5043	COG0154	amidase activity
Axylo_5044	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Axylo_5047	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Axylo_5048	COG0708	Exodeoxyribonuclease III
Axylo_5049	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Axylo_5051	COG0583	DNA-binding transcription factor activity
Axylo_5054	COG0583	DNA-binding transcription factor activity
Axylo_5057	COG0411	ABC transporter
Axylo_5060	COG1764	response to oxidative stress
Axylo_5061	COG1846	Transcriptional regulator
Axylo_5073	COG0640	Transcriptional regulator
Axylo_5078	COG0297	glycogen (starch) synthase activity
Axylo_5079	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Axylo_5080	COG3189	MarR family transcriptional regulator
Axylo_5084	COG1028	Short-chain dehydrogenase reductase Sdr
Axylo_5085	COG0351	phosphomethylpyrimidine kinase
Axylo_5085	COG0352	thiamine-phosphate diphosphorylase activity
Axylo_5085	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
Axylo_5088	COG3063	Type IV pilus biogenesis stability protein PilW
Axylo_5094	COG3210	domain, Protein
Axylo_5096	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
Axylo_5097	COG0513	Belongs to the DEAD box helicase family
Axylo_5099	COG0617	tRNA 3'-terminal CCA addition
Axylo_5101	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Axylo_5102	COG2308	Evidence 4 Homologs of previously reported genes of
Axylo_5104	COG1305	Transglutaminase-like
Axylo_5108	COG1950	PFAM Membrane protein of
Axylo_5109	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Axylo_5110	COG0438	transferase activity, transferring glycosyl groups
Axylo_5113	COG0066	3-isopropylmalate dehydratase activity
Axylo_5115	COG3181	Tripartite tricarboxylate transporter family receptor
Axylo_5116	COG0583	DNA-binding transcription factor activity
Axylo_5117	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Axylo_5124	COG0477	Major facilitator Superfamily
Axylo_5125	COG0154	amidase activity
Axylo_5126	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Axylo_5128	COG1560	Kdo2-lipid A biosynthetic process
Axylo_5129	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Axylo_5131	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
Axylo_5132	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
Axylo_5137	COG0735	belongs to the Fur family
Axylo_5138	COG0523	cobalamin synthesis protein
Axylo_5139	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Axylo_5140	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
Axylo_5141	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
Axylo_5143	COG2096	Adenosyltransferase
Axylo_5146	COG1091	dTDP-4-dehydrorhamnose reductase activity
Axylo_5147	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
Axylo_5149	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Axylo_5152	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Axylo_5154	COG0438	transferase activity, transferring glycosyl groups
Axylo_5158	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Axylo_5159	COG1609	Transcriptional regulator
Axylo_5161	COG0321	lipoyl(octanoyl) transferase activity
Axylo_5162	COG2921	Belongs to the UPF0250 family
Axylo_5164	COG1686	Belongs to the peptidase S11 family
Axylo_5169	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Axylo_5171	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
Axylo_5173	COG0859	PFAM glycosyl transferase family 9
Axylo_5174	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Axylo_5176	COG2814	Major facilitator Superfamily
Axylo_5179	COG3568	Endonuclease Exonuclease Phosphatase
Axylo_5180	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Axylo_5185	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Axylo_5188	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Axylo_5189	COG1956	GAF domain-containing protein
Axylo_5190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Axylo_5195	COG2186	Transcriptional regulator
Axylo_5196	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
Axylo_5202	COG2226	methyltransferase
Axylo_5203	COG0629	single-stranded DNA binding
Axylo_5204	COG2814	Major facilitator Superfamily
Axylo_5206	COG0625	glutathione transferase activity
Axylo_5207	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Axylo_5208	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Axylo_5209	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Axylo_5211	COG1965	Belongs to the frataxin family
Axylo_5213	COG0019	diaminopimelate decarboxylase activity
Axylo_5215	COG1333	cytochrome c biogenesis protein
Axylo_5217	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Axylo_5220	COG4232	protein-disulfide reductase activity
Axylo_5221	COG1324	tolerance protein
Axylo_5223	COG0203	ribosomal protein L17
Axylo_5224	COG0202	RNA polymerase activity
Axylo_5225	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Axylo_5226	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Axylo_5227	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Axylo_5228	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Axylo_5229	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Axylo_5230	COG0201	protein transport
Axylo_5231	COG0200	Binds to the 23S rRNA
Axylo_5232	COG1841	ribosomal large subunit assembly
Axylo_5233	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Axylo_5234	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Axylo_5235	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Axylo_5236	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Axylo_5237	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Axylo_5238	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Axylo_5239	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Axylo_5240	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Axylo_5244	COG2207	Transcriptional regulator
Axylo_5245	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Axylo_5247	COG0411	ABC transporter
Axylo_5248	COG0410	ABC transporter
Axylo_5252	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Axylo_5253	COG0255	Belongs to the universal ribosomal protein uL29 family
Axylo_5254	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Axylo_5255	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Axylo_5256	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Axylo_5257	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Axylo_5258	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Axylo_5259	COG0089	rRNA binding
Axylo_5260	COG0088	Forms part of the polypeptide exit tunnel
Axylo_5261	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Axylo_5262	COG0051	transcription antitermination factor activity, RNA binding
Axylo_5263	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Axylo_5264	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Axylo_5265	COG0049	tRNA binding
Axylo_5266	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Axylo_5267	COG0745	RESPONSE REGULATOR receiver
Axylo_5270	COG5002	protein histidine kinase activity
Axylo_5273	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Axylo_5274	COG0085	RNA polymerase activity
Axylo_5275	COG0222	ribosome binding
Axylo_5276	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Axylo_5277	COG0081	regulation of translation
Axylo_5278	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Axylo_5280	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Axylo_5282	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Axylo_5290	COG1840	ABC-type Fe3 transport system, periplasmic component
Axylo_5291	COG3842	ATPase activity
Axylo_5293	COG1349	DNA-binding transcription factor activity
Axylo_5298	COG0583	DNA-binding transcription factor activity
Axylo_5299	COG0252	asparaginase activity
Axylo_5300	COG1475	DNA binding
Axylo_5302	COG1192	Involved in chromosome partitioning
Axylo_5303	COG0357	Ribosomal RNA small subunit methyltransferase G
Axylo_5304	COG0445	tRNA wobble uridine modification
Axylo_5305	COG1278	Cold shock
Axylo_5306	COG3180	Ammonia monooxygenase
Axylo_5307	COG0436	Aminotransferase
Axylo_5313	COG0038	chloride channel
Axylo_5315	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Axylo_5317	COG0601	transmembrane transport
Axylo_5318	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Axylo_5319	COG0444	Belongs to the ABC transporter superfamily
Axylo_5320	COG4608	Belongs to the ABC transporter superfamily
Axylo_5321	COG1473	amidohydrolase
Axylo_5325	COG0753	catalase activity
Axylo_5327	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Axylo_5328	COG0594	ribonuclease P activity
Axylo_5329	COG0230	Belongs to the bacterial ribosomal protein bL34 family