locus-tag	class	description
AX27061_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AX27061_0002	COG0592	DNA-directed DNA polymerase activity
AX27061_0004	COG2814	Major facilitator Superfamily
AX27061_0005	COG0583	DNA-binding transcription factor activity
AX27061_0006	COG0583	DNA-binding transcription factor activity
AX27061_0011	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AX27061_0013	COG0583	DNA-binding transcription factor activity
AX27061_0014	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AX27061_0015	COG0765	amino acid transport
AX27061_0016	COG0765	amino acid transport
AX27061_0017	COG1126	abc transporter atp-binding protein
AX27061_0020	COG1254	Belongs to the acylphosphatase family
AX27061_0022	COG1304	FMN binding
AX27061_0024	COG3842	ATPase activity
AX27061_0025	COG1176	ABC-type spermidine putrescine transport system, permease component I
AX27061_0026	COG1177	transmembrane transport
AX27061_0037	COG1609	Transcriptional regulator
AX27061_0039	COG3842	ATPase activity
AX27061_0040	COG1176	ABC-type spermidine putrescine transport system, permease component I
AX27061_0041	COG1177	transmembrane transport
AX27061_0046	COG0251	oxidation-reduction process
AX27061_0047	COG0402	S-adenosylhomocysteine deaminase activity
AX27061_0051	COG1744	ABC transporter substrate-binding protein PnrA-like
AX27061_0055	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AX27061_0058	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AX27061_0061	COG2814	Major facilitator Superfamily
AX27061_0062	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AX27061_0064	COG3781	membrane
AX27061_0065	COG1522	sequence-specific DNA binding
AX27061_0066	COG0028	Belongs to the TPP enzyme family
AX27061_0067	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_0068	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AX27061_0069	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AX27061_0073	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AX27061_0074	COG2922	Belongs to the Smg family
AX27061_0081	COG0765	amino acid transport
AX27061_0082	COG0765	amino acid transport
AX27061_0083	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AX27061_0085	COG3181	Tripartite tricarboxylate transporter family receptor
AX27061_0086	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AX27061_0090	COG2814	Major facilitator Superfamily
AX27061_0092	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
AX27061_0094	COG3339	Conserved Protein
AX27061_0100	COG2186	Transcriptional regulator
AX27061_0101	COG2814	Major facilitator Superfamily
AX27061_0104	COG1595	DNA-templated transcription, initiation
AX27061_0105	COG0318	PFAM AMP-dependent synthetase and ligase
AX27061_0108	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_0118	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AX27061_0119	COG0183	Belongs to the thiolase family
AX27061_0120	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AX27061_0121	COG1960	acyl-CoA dehydrogenase activity
AX27061_0122	COG1473	amidohydrolase
AX27061_0124	COG1742	UPF0060 membrane protein
AX27061_0127	COG1280	lysine exporter protein (LysE YggA)
AX27061_0132	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AX27061_0134	COG0018	arginyl-trna synthetase
AX27061_0138	COG0395	ABC-type sugar transport system, permease component
AX27061_0139	COG1175	transmembrane transport
AX27061_0140	COG1653	transport
AX27061_0142	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AX27061_0143	COG1609	Transcriptional regulator
AX27061_0145	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AX27061_0148	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AX27061_0151	COG0583	DNA-binding transcription factor activity
AX27061_0155	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AX27061_0156	COG1280	lysine exporter protein (LysE YggA)
AX27061_0158	COG0513	Belongs to the DEAD box helicase family
AX27061_0159	COG5339	Protein conserved in bacteria
AX27061_0160	COG5339	Protein conserved in bacteria
AX27061_0161	COG1228	amidohydrolase
AX27061_0163	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AX27061_0164	COG0601	transmembrane transport
AX27061_0165	COG0747	negative chemotaxis
AX27061_0166	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AX27061_0168	COG2207	Transcriptional regulator
AX27061_0168	COG3708	Transcriptional regulator
AX27061_0170	COG1104	cysteine desulfurase activity
AX27061_0172	COG0583	DNA-binding transcription factor activity
AX27061_0176	COG2969	positive regulation of protein catabolic process
AX27061_0177	COG0625	glutathione transferase activity
AX27061_0178	COG2857	Cytochrome c1
AX27061_0179	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AX27061_0180	COG0723	plastoquinol--plastocyanin reductase activity
AX27061_0181	COG1970	mechanosensitive ion channel activity
AX27061_0182	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AX27061_0183	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AX27061_0186	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AX27061_0187	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AX27061_0188	COG0537	adenosine 5'-monophosphoramidase activity
AX27061_0189	COG0140	phosphoribosyl-ATP diphosphatase activity
AX27061_0190	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AX27061_0191	COG0107	imidazoleglycerol-phosphate synthase activity
AX27061_0192	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AX27061_0193	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AX27061_0194	COG0131	Imidazoleglycerol-phosphate dehydratase
AX27061_0195	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AX27061_0196	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AX27061_0197	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AX27061_0198	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AX27061_0200	COG0842	Transport permease protein
AX27061_0201	COG1131	(ABC) transporter
AX27061_0203	COG2853	Lipoprotein
AX27061_0204	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AX27061_0205	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AX27061_0206	COG1127	ABC transporter
AX27061_0207	COG2070	2-Nitropropane dioxygenase
AX27061_0209	COG0477	Major facilitator Superfamily
AX27061_0212	COG0583	DNA-binding transcription factor activity
AX27061_0213	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AX27061_0214	COG0511	ligase activity, forming carbon-carbon bonds
AX27061_0217	COG1984	allophanate hydrolase subunit 2
AX27061_0220	COG0067	glutamate synthase
AX27061_0220	COG0069	glutamate synthase activity
AX27061_0220	COG0070	glutamate synthase
AX27061_0225	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AX27061_0229	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AX27061_0232	COG1845	cytochrome c oxidase, subunit III
AX27061_0236	COG1612	heme a metabolic process
AX27061_0237	COG0109	protoheme IX farnesyltransferase activity
AX27061_0238	COG1999	signal sequence binding
AX27061_0242	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AX27061_0243	COG2814	Major facilitator Superfamily
AX27061_0245	COG0438	transferase activity, transferring glycosyl groups
AX27061_0247	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AX27061_0249	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AX27061_0252	COG4774	siderophore transport
AX27061_0253	COG4592	Periplasmic binding protein
AX27061_0254	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AX27061_0255	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AX27061_0256	COG1120	ATPase activity
AX27061_0260	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AX27061_0265	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AX27061_0266	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AX27061_0267	COG2814	Major facilitator Superfamily
AX27061_0268	COG0583	DNA-binding transcription factor activity
AX27061_0270	COG2423	ornithine cyclodeaminase activity
AX27061_0271	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AX27061_0272	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AX27061_0274	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AX27061_0276	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AX27061_0277	COG0463	Glycosyl transferase, family 2
AX27061_0287	COG0737	Belongs to the 5'-nucleotidase family
AX27061_0290	COG2188	Transcriptional regulator
AX27061_0292	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AX27061_0293	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AX27061_0296	COG0840	transmembrane signaling receptor activity
AX27061_0297	COG2814	Major facilitator Superfamily
AX27061_0300	COG3188	usher protein
AX27061_0312	COG1802	Transcriptional regulator
AX27061_0315	COG3069	C4-dicarboxylate transmembrane transporter activity
AX27061_0321	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AX27061_0323	COG0747	negative chemotaxis
AX27061_0328	COG1464	Belongs to the NlpA lipoprotein family
AX27061_0329	COG0431	NADPH-dependent FMN reductase
AX27061_0330	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AX27061_0331	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AX27061_0332	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AX27061_0335	COG2011	ABC-type metal ion transport system permease component
AX27061_0336	COG1464	Belongs to the NlpA lipoprotein family
AX27061_0337	COG1116	anion transmembrane transporter activity
AX27061_0338	COG3585	molybdate ion transport
AX27061_0339	COG3064	Membrane
AX27061_0344	COG1607	acyl-coa hydrolase
AX27061_0347	COG0437	4 iron, 4 sulfur cluster binding
AX27061_0348	COG2864	formate dehydrogenase
AX27061_0351	COG3276	selenocysteine insertion sequence binding
AX27061_0352	COG1216	Glycosyl transferase, family 2
AX27061_0353	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AX27061_0354	COG1305	Transglutaminase-like
AX27061_0356	COG0709	Synthesizes selenophosphate from selenide and ATP
AX27061_0363	COG1012	belongs to the aldehyde dehydrogenase family
AX27061_0364	COG3284	Transcriptional regulator
AX27061_0365	COG0134	indole-3-glycerol-phosphate synthase activity
AX27061_0366	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AX27061_0367	COG0512	Glutamine amidotransferase of anthranilate synthase
AX27061_0370	COG0546	phosphoglycolate phosphatase activity
AX27061_0372	COG2967	ApaG domain
AX27061_0374	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AX27061_0375	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AX27061_0377	COG0037	tRNA processing
AX27061_0384	COG0559	Belongs to the binding-protein-dependent transport system permease family
AX27061_0385	COG0559	Belongs to the binding-protein-dependent transport system permease family
AX27061_0388	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AX27061_0393	COG3473	Maleate cis-trans isomerase
AX27061_0394	COG0583	DNA-binding transcription factor activity
AX27061_0397	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AX27061_0399	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AX27061_0400	COG1024	Enoyl-CoA hydratase
AX27061_0404	COG0356	it plays a direct role in the translocation of protons across the membrane
AX27061_0406	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AX27061_0407	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AX27061_0408	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AX27061_0409	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AX27061_0410	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AX27061_0411	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AX27061_0413	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AX27061_0414	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AX27061_0415	COG0210	DNA helicase
AX27061_0418	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AX27061_0421	COG2171	N-acyltransferase activity
AX27061_0423	COG2195	Cleaves the N-terminal amino acid of tripeptides
AX27061_0425	COG4608	Belongs to the ABC transporter superfamily
AX27061_0426	COG0444	Belongs to the ABC transporter superfamily
AX27061_0428	COG0601	transmembrane transport
AX27061_0429	COG0747	negative chemotaxis
AX27061_0430	COG2988	succinylglutamate desuccinylase activity
AX27061_0432	COG0583	DNA-binding transcription factor activity
AX27061_0433	COG0747	negative chemotaxis
AX27061_0435	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AX27061_0436	COG1024	Enoyl-CoA hydratase
AX27061_0437	COG1024	Enoyl-CoA hydratase
AX27061_0439	COG1309	transcriptional regulator
AX27061_0442	COG1250	3-hydroxyacyl-CoA dehydrogenase
AX27061_0444	COG2814	Major facilitator Superfamily
AX27061_0447	COG1764	response to oxidative stress
AX27061_0448	COG0583	DNA-binding transcription factor activity
AX27061_0450	COG1595	DNA-templated transcription, initiation
AX27061_0451	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AX27061_0452	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AX27061_0455	COG0179	Fumarylacetoacetate (FAA) hydrolase
AX27061_0457	COG0559	Belongs to the binding-protein-dependent transport system permease family
AX27061_0459	COG1129	ABC transporter
AX27061_0462	COG1802	Transcriptional regulator
AX27061_0464	COG0583	DNA-binding transcription factor activity
AX27061_0467	COG2988	succinylglutamate desuccinylase activity
AX27061_0469	COG2918	glutathione biosynthetic process
AX27061_0476	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AX27061_0477	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AX27061_0479	COG2721	sulfolactate sulfo-lyase activity
AX27061_0480	COG2721	sulfolactate sulfo-lyase activity
AX27061_0481	COG2188	Transcriptional regulator
AX27061_0482	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AX27061_0483	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AX27061_0483	COG2813	Specifically methylates the guanine in position
AX27061_0484	COG2223	nitrite transmembrane transporter activity
AX27061_0486	COG2860	membrane
AX27061_0487	COG1802	Transcriptional regulator
AX27061_0488	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AX27061_0489	COG1984	allophanate hydrolase subunit 2
AX27061_0490	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AX27061_0492	COG0583	DNA-binding transcription factor activity
AX27061_0494	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AX27061_0498	COG2132	Multicopper oxidase
AX27061_0503	COG0745	RESPONSE REGULATOR receiver
AX27061_0504	COG2226	methyltransferase
AX27061_0507	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AX27061_0509	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AX27061_0511	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AX27061_0512	COG0351	phosphomethylpyrimidine kinase
AX27061_0513	COG2022	thiamine diphosphate biosynthetic process
AX27061_0514	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AX27061_0515	COG4771	TonB-dependent receptor
AX27061_0518	COG2186	Transcriptional regulator
AX27061_0521	COG1063	alcohol dehydrogenase
AX27061_0523	COG0765	amino acid transport
AX27061_0524	COG1126	abc transporter atp-binding protein
AX27061_0525	COG4948	Mandelate Racemase Muconate Lactonizing
AX27061_0526	COG0246	Mannitol dehydrogenase
AX27061_0529	COG1194	a g-specific adenine glycosylase
AX27061_0533	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AX27061_0534	COG2177	Part of the ABC transporter FtsEX involved in
AX27061_0535	COG2884	Cell division ATP-binding protein ftsE
AX27061_0536	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AX27061_0537	COG4597	amino acid ABC transporter
AX27061_0538	COG0765	amino acid transport
AX27061_0539	COG1126	abc transporter atp-binding protein
AX27061_0543	COG0410	ABC transporter
AX27061_0544	COG1129	ABC transporter
AX27061_0545	COG4177	L-phenylalanine transmembrane transporter activity
AX27061_0546	COG0559	Belongs to the binding-protein-dependent transport system permease family
AX27061_0548	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AX27061_0549	COG2081	HI0933 family
AX27061_0551	COG1605	Chorismate mutase
AX27061_0551	COG0077	Prephenate dehydratase
AX27061_0557	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AX27061_0558	COG0477	Major facilitator Superfamily
AX27061_0560	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AX27061_0561	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AX27061_0565	COG0237	dephospho-CoA kinase activity
AX27061_0566	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AX27061_0570	COG1538	Outer membrane efflux protein
AX27061_0572	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AX27061_0573	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AX27061_0576	COG3833	ABC-type maltose transport systems, permease component
AX27061_0577	COG1175	transmembrane transport
AX27061_0578	COG3842	ATPase activity
AX27061_0582	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AX27061_0586	COG0559	Belongs to the binding-protein-dependent transport system permease family
AX27061_0589	COG0410	ABC transporter
AX27061_0593	COG3706	GGDEF domain
AX27061_0596	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_0597	COG1024	Enoyl-CoA hydratase
AX27061_0605	COG4638	Rieske (2fe-2S)
AX27061_0606	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AX27061_0607	COG1335	isochorismatase
AX27061_0608	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_0610	COG0741	lytic transglycosylase activity
AX27061_0611	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AX27061_0614	COG1773	rubredoxin
AX27061_0615	COG1678	Uncharacterized ACR, COG1678
AX27061_0616	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AX27061_0617	COG0540	Belongs to the ATCase OTCase family
AX27061_0622	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AX27061_0624	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AX27061_0626	COG0765	amino acid transport
AX27061_0627	COG1126	abc transporter atp-binding protein
AX27061_0628	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AX27061_0630	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AX27061_0631	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AX27061_0633	COG3842	ATPase activity
AX27061_0634	COG1175	transmembrane transport
AX27061_0636	COG0642	Histidine kinase
AX27061_0638	COG0557	exoribonuclease II activity
AX27061_0639	COG3150	esterase
AX27061_0640	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AX27061_0641	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AX27061_0642	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AX27061_0643	COG0511	ligase activity, forming carbon-carbon bonds
AX27061_0644	COG0439	Biotin carboxylase
AX27061_0645	COG2264	protein methyltransferase activity
AX27061_0647	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AX27061_0647	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AX27061_0652	COG1696	Membrane protein involved in D-alanine export
AX27061_0660	COG1522	sequence-specific DNA binding
AX27061_0661	COG3181	Tripartite tricarboxylate transporter family receptor
AX27061_0663	COG0583	DNA-binding transcription factor activity
AX27061_0666	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AX27061_0667	COG1042	CoA-binding domain protein
AX27061_0667	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AX27061_0667	COG0045	succinate-CoA ligase (ADP-forming) activity
AX27061_0668	COG1335	isochorismatase
AX27061_0669	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AX27061_0670	COG1116	anion transmembrane transporter activity
AX27061_0673	COG3028	Belongs to the UPF0307 family
AX27061_0674	COG0312	modulator of DNA gyrase
AX27061_0675	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AX27061_0678	COG4177	L-phenylalanine transmembrane transporter activity
AX27061_0681	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AX27061_0682	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AX27061_0684	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AX27061_0686	COG0316	Belongs to the HesB IscA family
AX27061_0687	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AX27061_0690	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AX27061_0693	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AX27061_0694	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AX27061_0698	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AX27061_0698	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AX27061_0701	COG2766	serine protein kinase
AX27061_0702	COG2718	Belongs to the UPF0229 family
AX27061_0703	COG2719	SpoVR family
AX27061_0704	COG0583	DNA-binding transcription factor activity
AX27061_0705	COG1942	4-Oxalocrotonate Tautomerase
AX27061_0708	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AX27061_0710	COG3181	Tripartite tricarboxylate transporter family receptor
AX27061_0714	COG2208	phosphoserine phosphatase activity
AX27061_0714	COG2770	Histidine kinase
AX27061_0717	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AX27061_0718	COG2172	sigma factor antagonist activity
AX27061_0719	COG1366	Belongs to the anti-sigma-factor antagonist family
AX27061_0727	COG1388	LysM domain
AX27061_0727	COG0741	lytic transglycosylase activity
AX27061_0729	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AX27061_0730	COG2226	methyltransferase
AX27061_0731	COG0328	RNA-DNA hybrid ribonuclease activity
AX27061_0733	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AX27061_0734	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AX27061_0736	COG1671	Belongs to the UPF0178 family
AX27061_0739	COG0786	glutamate:sodium symporter activity
AX27061_0742	COG0463	Glycosyl transferase, family 2
AX27061_0743	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AX27061_0746	COG0583	DNA-binding transcription factor activity
AX27061_0750	COG0559	Belongs to the binding-protein-dependent transport system permease family
AX27061_0754	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AX27061_0756	COG0583	DNA-binding transcription factor activity
AX27061_0758	COG1346	cytolysis
AX27061_0760	COG0697	spore germination
AX27061_0761	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AX27061_0764	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AX27061_0766	COG1522	sequence-specific DNA binding
AX27061_0769	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AX27061_0770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AX27061_0773	COG0823	Involved in the tonB-independent uptake of proteins
AX27061_0775	COG0848	biopolymer transport protein
AX27061_0776	COG0811	peptide transport
AX27061_0777	COG0824	Thioesterase
AX27061_0778	COG0442	prolyl-tRNA aminoacylation
AX27061_0785	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AX27061_0787	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AX27061_0788	COG2084	Dehydrogenase
AX27061_0789	COG0405	Gamma-glutamyltransferase
AX27061_0796	COG0129	dihydroxy-acid dehydratase activity
AX27061_0797	COG4654	Cytochrome c, class I
AX27061_0798	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AX27061_0800	COG1522	sequence-specific DNA binding
AX27061_0803	COG0583	DNA-binding transcription factor activity
AX27061_0805	COG1473	amidohydrolase
AX27061_0806	COG0418	dihydroorotase activity
AX27061_0808	COG2001	Belongs to the MraZ family
AX27061_0809	COG0275	rRNA processing
AX27061_0810	COG3116	cell division
AX27061_0812	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AX27061_0813	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AX27061_0814	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AX27061_0816	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AX27061_0817	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AX27061_0818	COG1181	Belongs to the D-alanine--D-alanine ligase family
AX27061_0819	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AX27061_0821	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AX27061_0822	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AX27061_0824	COG0739	heme binding
AX27061_0825	COG0653	protein targeting
AX27061_0830	COG0028	Belongs to the TPP enzyme family
AX27061_0832	COG0300	oxidoreductase activity
AX27061_0833	COG1522	sequence-specific DNA binding
AX27061_0836	COG2239	Acts as a magnesium transporter
AX27061_0837	COG1607	acyl-coa hydrolase
AX27061_0838	COG2855	membrane
AX27061_0839	COG0583	DNA-binding transcription factor activity
AX27061_0840	COG1473	amidohydrolase
AX27061_0841	COG0318	PFAM AMP-dependent synthetase and ligase
AX27061_0842	COG0483	inositol monophosphate 1-phosphatase activity
AX27061_0843	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AX27061_0843	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AX27061_0845	COG1501	Belongs to the glycosyl hydrolase 31 family
AX27061_0846	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AX27061_0847	COG2011	ABC-type metal ion transport system permease component
AX27061_0849	COG1595	DNA-templated transcription, initiation
AX27061_0850	COG3712	iron ion homeostasis
AX27061_0854	COG0840	transmembrane signaling receptor activity
AX27061_0855	COG0583	DNA-binding transcription factor activity
AX27061_0857	COG0735	belongs to the Fur family
AX27061_0862	COG2818	Glycosylase
AX27061_0863	COG1368	sulfuric ester hydrolase activity
AX27061_0864	COG2982	Protein involved in outer membrane biogenesis
AX27061_0867	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_0873	COG2154	pterin-4-alpha-carbinolamine dehydratase
AX27061_0876	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AX27061_0879	COG3178	'Phosphotransferase
AX27061_0881	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AX27061_0882	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AX27061_0883	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AX27061_0884	COG1929	Belongs to the glycerate kinase type-1 family
AX27061_0885	COG0469	pyruvate kinase activity
AX27061_0886	COG0700	Nucleoside recognition
AX27061_0887	COG1960	acyl-CoA dehydrogenase activity
AX27061_0888	COG0242	peptide deformylase activity
AX27061_0892	COG0204	Acyl-transferase
AX27061_0893	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AX27061_0894	COG0751	glycine-tRNA ligase activity
AX27061_0895	COG0752	glycyl-tRNA synthetase alpha subunit
AX27061_0897	COG1024	Enoyl-CoA hydratase
AX27061_0901	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AX27061_0902	COG2030	dehydratase
AX27061_0903	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_0906	COG2070	2-Nitropropane dioxygenase
AX27061_0908	COG0318	PFAM AMP-dependent synthetase and ligase
AX27061_0909	COG0183	Belongs to the thiolase family
AX27061_0911	COG1960	acyl-CoA dehydrogenase activity
AX27061_0913	COG1024	Enoyl-CoA hydratase
AX27061_0915	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
AX27061_0917	COG2301	Belongs to the HpcH HpaI aldolase family
AX27061_0918	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AX27061_0920	COG0617	tRNA 3'-terminal CCA addition
AX27061_0923	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AX27061_0925	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AX27061_0926	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AX27061_0927	COG0586	Pfam SNARE associated Golgi protein
AX27061_0929	COG0860	N-Acetylmuramoyl-L-alanine amidase
AX27061_0931	COG0114	fumarate hydratase activity
AX27061_0933	COG3181	Tripartite tricarboxylate transporter family receptor
AX27061_0936	COG0531	amino acid
AX27061_0938	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AX27061_0940	COG1960	acyl-CoA dehydrogenase activity
AX27061_0941	COG0583	DNA-binding transcription factor activity
AX27061_0942	COG0179	Fumarylacetoacetate (FAA) hydrolase
AX27061_0944	COG1304	FMN binding
AX27061_0948	COG0583	DNA-binding transcription factor activity
AX27061_0950	COG0579	oxidoreductase
AX27061_0952	COG0259	pyridoxamine-phosphate oxidase activity
AX27061_0955	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AX27061_0956	COG0577	efflux transmembrane transporter activity
AX27061_0956	COG1136	(ABC) transporter
AX27061_0957	COG1538	Outer membrane efflux protein
AX27061_0958	COG0583	DNA-binding transcription factor activity
AX27061_0960	COG0577	efflux transmembrane transporter activity
AX27061_0960	COG1136	(ABC) transporter
AX27061_0962	COG1566	PFAM secretion protein HlyD family protein
AX27061_0963	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AX27061_0970	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AX27061_0973	COG0800	Aldolase
AX27061_0977	COG1216	Glycosyl transferase, family 2
AX27061_0977	COG0463	Glycosyl transferase, family 2
AX27061_0978	COG0410	ABC transporter
AX27061_0979	COG0411	ABC transporter
AX27061_0982	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_0983	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AX27061_0987	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AX27061_0988	COG4638	Rieske (2fe-2S)
AX27061_0993	COG0747	negative chemotaxis
AX27061_0995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AX27061_0996	COG0444	Belongs to the ABC transporter superfamily
AX27061_0997	COG4608	Belongs to the ABC transporter superfamily
AX27061_1001	COG2746	aminoglycoside 3-N-acetyltransferase activity
AX27061_1002	COG0488	(ABC) transporter
AX27061_1005	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AX27061_1006	COG2894	cell division
AX27061_1007	COG0850	regulation of cytokinetic process
AX27061_1008	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AX27061_1010	COG1294	oxidase, subunit
AX27061_1011	COG0514	ATP-dependent DNA helicase (RecQ)
AX27061_1013	COG0745	RESPONSE REGULATOR receiver
AX27061_1014	COG4191	Histidine kinase
AX27061_1015	COG2255	four-way junction helicase activity
AX27061_1017	COG1090	epimerase
AX27061_1018	COG0632	four-way junction helicase activity
AX27061_1023	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AX27061_1025	COG0006	proline dipeptidase activity
AX27061_1029	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AX27061_1030	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AX27061_1033	COG4783	chaperone-mediated protein folding
AX27061_1041	COG2814	Major facilitator Superfamily
AX27061_1042	COG4771	TonB-dependent receptor
AX27061_1045	COG0513	Belongs to the DEAD box helicase family
AX27061_1049	COG1414	Transcriptional regulator
AX27061_1052	COG0167	dihydroorotate dehydrogenase activity
AX27061_1053	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AX27061_1054	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AX27061_1064	COG1192	Involved in chromosome partitioning
AX27061_1071	COG0629	single-stranded DNA binding
AX27061_1072	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AX27061_1075	COG0789	Transcriptional regulator
AX27061_1077	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AX27061_1085	COG0789	Transcriptional regulator
AX27061_1099	COG3344	reverse transcriptase
AX27061_1104	COG3344	reverse transcriptase
AX27061_1121	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AX27061_1122	COG1569	PIN domain
AX27061_1123	COG3311	Transcriptional regulator
AX27061_1146	COG0024	Methionine aminopeptidase
AX27061_1151	COG2807	transmembrane transport
AX27061_1154	COG4771	TonB-dependent receptor
AX27061_1159	COG1131	(ABC) transporter
AX27061_1161	COG0019	diaminopimelate decarboxylase activity
AX27061_1164	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AX27061_1165	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AX27061_1166	COG4774	siderophore transport
AX27061_1177	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AX27061_1178	COG0640	Transcriptional regulator
AX27061_1183	COG4771	TonB-dependent receptor
AX27061_1186	COG2814	Major facilitator Superfamily
AX27061_1188	COG4106	trans-aconitate 2-methyltransferase activity
AX27061_1197	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AX27061_1197	COG2226	methyltransferase
AX27061_1197	COG3433	isochorismatase activity
AX27061_1200	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AX27061_1201	COG1021	2,3-dihydroxybenzoate-AMP ligase
AX27061_1202	COG0582	viral genome integration into host DNA
AX27061_1204	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AX27061_1205	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AX27061_1206	COG0735	belongs to the Fur family
AX27061_1207	COG0497	DNA recombination
AX27061_1208	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AX27061_1209	COG1420	regulation of RNA biosynthetic process
AX27061_1210	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AX27061_1212	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AX27061_1214	COG0443	Heat shock 70 kDa protein
AX27061_1215	COG0484	heat shock protein binding
AX27061_1217	COG0612	Peptidase, M16
AX27061_1222	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AX27061_1229	COG0840	transmembrane signaling receptor activity
AX27061_1230	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AX27061_1233	COG0745	RESPONSE REGULATOR receiver
AX27061_1234	COG2205	protein histidine kinase activity
AX27061_1235	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AX27061_1236	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AX27061_1239	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AX27061_1241	COG1193	negative regulation of DNA recombination
AX27061_1242	COG0492	ferredoxin-NADP+ reductase activity
AX27061_1244	COG1674	ftsk spoiiie
AX27061_1245	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AX27061_1246	COG0251	oxidation-reduction process
AX27061_1247	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AX27061_1248	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AX27061_1248	COG0517	IMP dehydrogenase activity
AX27061_1252	COG0601	transmembrane transport
AX27061_1255	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AX27061_1256	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AX27061_1257	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AX27061_1266	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AX27061_1268	COG4774	siderophore transport
AX27061_1270	COG4607	ABC-type enterochelin transport system periplasmic component
AX27061_1271	COG4604	ABC transporter, ATP-binding protein
AX27061_1272	COG4605	iron ion homeostasis
AX27061_1273	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AX27061_1279	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_1280	COG3022	response to hydroperoxide
AX27061_1281	COG1289	transmembrane transporter activity
AX27061_1282	COG0028	Belongs to the TPP enzyme family
AX27061_1283	COG0440	acetolactate synthase activity
AX27061_1284	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AX27061_1285	COG1183	phosphatidylcholine synthase activity
AX27061_1288	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AX27061_1289	COG1185	polyribonucleotide nucleotidyltransferase activity
AX27061_1291	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AX27061_1293	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AX27061_1299	COG0149	triose-phosphate isomerase activity
AX27061_1300	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AX27061_1302	COG2885	chlorophyll binding
AX27061_1302	COG3047	cAMP biosynthetic process
AX27061_1307	COG0840	transmembrane signaling receptor activity
AX27061_1311	COG1910	domain protein
AX27061_1318	COG1116	anion transmembrane transporter activity
AX27061_1321	COG1595	DNA-templated transcription, initiation
AX27061_1322	COG3712	iron ion homeostasis
AX27061_1326	COG0642	Histidine kinase
AX27061_1328	COG2851	Citrate transporter
AX27061_1329	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_1331	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AX27061_1332	COG3706	GGDEF domain
AX27061_1332	COG0745	RESPONSE REGULATOR receiver
AX27061_1333	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AX27061_1334	COG4191	Histidine kinase
AX27061_1334	COG0784	Response regulator, receiver
AX27061_1337	COG3604	Transcriptional regulator
AX27061_1338	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
AX27061_1339	COG3813	Protein conserved in bacteria
AX27061_1340	COG2354	Protein conserved in bacteria
AX27061_1341	COG4772	TonB-dependent receptor
AX27061_1342	COG1522	sequence-specific DNA binding
AX27061_1346	COG4172	Belongs to the ABC transporter superfamily
AX27061_1348	COG0747	negative chemotaxis
AX27061_1352	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AX27061_1353	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AX27061_1355	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AX27061_1356	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AX27061_1357	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AX27061_1361	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AX27061_1363	COG1309	transcriptional regulator
AX27061_1364	COG0583	DNA-binding transcription factor activity
AX27061_1368	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AX27061_1373	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AX27061_1374	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AX27061_1375	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AX27061_1376	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AX27061_1377	COG0649	NAD binding
AX27061_1378	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AX27061_1380	COG1034	ATP synthesis coupled electron transport
AX27061_1381	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AX27061_1382	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AX27061_1384	COG0713	ATP synthesis coupled electron transport
AX27061_1387	COG1007	ATP synthesis coupled electron transport
AX27061_1390	COG4774	siderophore transport
AX27061_1391	COG4774	siderophore transport
AX27061_1392	COG0560	Phosphoserine phosphatase
AX27061_1393	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AX27061_1394	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AX27061_1395	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AX27061_1397	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AX27061_1398	COG0450	alkyl hydroperoxide reductase
AX27061_1399	COG2205	protein histidine kinase activity
AX27061_1400	COG0745	RESPONSE REGULATOR receiver
AX27061_1401	COG1214	PFAM Peptidase M22, glycoprotease
AX27061_1402	COG1573	uracil-dna glycosylase
AX27061_1403	COG0477	Major facilitator Superfamily
AX27061_1405	COG1196	nuclear chromosome segregation
AX27061_1407	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AX27061_1408	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AX27061_1410	COG2917	probably involved in intracellular septation
AX27061_1411	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AX27061_1412	COG1122	ATPase activity
AX27061_1413	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AX27061_1414	COG1268	BioY protein
AX27061_1417	COG0411	ABC transporter
AX27061_1421	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AX27061_1427	COG0411	ABC transporter
AX27061_1428	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AX27061_1429	COG2878	Part of a membrane complex involved in electron transport
AX27061_1433	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AX27061_1434	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AX27061_1435	COG0251	oxidation-reduction process
AX27061_1437	COG3228	Belongs to the MtfA family
AX27061_1438	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AX27061_1440	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AX27061_1441	COG0133	tryptophan synthase activity
AX27061_1442	COG0159	tryptophan synthase activity
AX27061_1443	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AX27061_1444	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AX27061_1445	COG1530	ribonuclease E activity
AX27061_1446	COG0564	pseudouridine synthase activity
AX27061_1447	COG0546	phosphoglycolate phosphatase activity
AX27061_1448	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AX27061_1449	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AX27061_1452	COG0424	maF-like protein
AX27061_1453	COG1399	metal-binding, possibly nucleic acid-binding protein
AX27061_1454	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AX27061_1455	COG0416	fatty acid biosynthetic process
AX27061_1456	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AX27061_1457	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AX27061_1459	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AX27061_1460	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AX27061_1465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AX27061_1466	COG0481	GTPase activity
AX27061_1467	COG0681	Belongs to the peptidase S26 family
AX27061_1468	COG0571	ribonuclease III activity
AX27061_1469	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AX27061_1470	COG1381	Involved in DNA repair and RecF pathway recombination
AX27061_1480	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AX27061_1485	COG0583	DNA-binding transcription factor activity
AX27061_1487	COG0791	NLP P60 protein
AX27061_1490	COG3193	protein, possibly involved in utilization of glycolate and propanediol
AX27061_1494	COG0697	spore germination
AX27061_1495	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AX27061_1500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AX27061_1505	COG2153	protein acetylation
AX27061_1507	COG1446	asparaginase
AX27061_1508	COG4172	Belongs to the ABC transporter superfamily
AX27061_1509	COG0747	negative chemotaxis
AX27061_1516	COG0504	CTP synthase activity
AX27061_1518	COG0148	phosphopyruvate hydratase activity
AX27061_1521	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AX27061_1523	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AX27061_1534	COG0039	L-malate dehydrogenase activity
AX27061_1535	COG2188	Transcriptional regulator
AX27061_1536	COG2009	succinate dehydrogenase
AX27061_1537	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AX27061_1538	COG1053	succinate dehydrogenase
AX27061_1539	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AX27061_1540	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AX27061_1541	COG0372	Belongs to the citrate synthase family
AX27061_1544	COG0280	phosphate acetyltransferase
AX27061_1544	COG0281	malic enzyme
AX27061_1546	COG1297	OPT oligopeptide transporter protein
AX27061_1547	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AX27061_1550	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AX27061_1551	COG1522	sequence-specific DNA binding
AX27061_1552	COG0567	Dehydrogenase, E1 component
AX27061_1553	COG0508	dehydrogenase complex catalyzes the overall conversion of
AX27061_1554	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AX27061_1555	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AX27061_1556	COG1595	DNA-templated transcription, initiation
AX27061_1557	COG3712	iron ion homeostasis
AX27061_1558	COG4774	siderophore transport
AX27061_1563	COG0180	Tryptophanyl-tRNA synthetase
AX27061_1565	COG2183	response to ionizing radiation
AX27061_1566	COG1199	ATP-dependent helicase activity
AX27061_1568	COG0564	pseudouridine synthase activity
AX27061_1570	COG3243	poly(R)-hydroxyalkanoic acid synthase
AX27061_1571	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_1572	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
AX27061_1577	COG2831	hemolysin activation secretion protein
AX27061_1578	COG3210	domain, Protein
AX27061_1580	COG2823	Periplasmic or secreted lipoprotein
AX27061_1582	COG3237	CsbD-like
AX27061_1584	COG0189	ligase activity
AX27061_1584	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AX27061_1585	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AX27061_1585	COG0189	ligase activity
AX27061_1586	COG1132	(ABC) transporter
AX27061_1589	COG2833	Protein of unknown function (DUF455)
AX27061_1590	COG2258	MOSC domain
AX27061_1591	COG2951	lytic endotransglycosylase activity
AX27061_1594	COG1960	acyl-CoA dehydrogenase activity
AX27061_1596	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AX27061_1598	COG1696	Membrane protein involved in D-alanine export
AX27061_1602	COG1215	transferase activity, transferring glycosyl groups
AX27061_1604	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AX27061_1609	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AX27061_1612	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AX27061_1616	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AX27061_1617	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AX27061_1621	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AX27061_1622	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AX27061_1623	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AX27061_1629	COG2951	lytic endotransglycosylase activity
AX27061_1630	COG0123	including yeast histone deacetylase and acetoin utilization protein
AX27061_1635	COG2985	domain, Protein
AX27061_1636	COG1960	acyl-CoA dehydrogenase activity
AX27061_1637	COG0450	alkyl hydroperoxide reductase
AX27061_1639	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AX27061_1640	COG4208	sulfate ABC transporter
AX27061_1642	COG0175	sulfate reduction
AX27061_1648	COG0335	large ribosomal subunit rRNA binding
AX27061_1650	COG1162	GTPase activity
AX27061_1651	COG0501	Belongs to the peptidase M48B family
AX27061_1652	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AX27061_1653	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AX27061_1654	COG3327	negative regulation of DNA-templated transcription, initiation
AX27061_1655	COG3396	Phenylacetate-CoA oxygenase
AX27061_1656	COG3460	Phenylacetate-CoA oxygenase
AX27061_1657	COG3396	Phenylacetate-CoA oxygenase
AX27061_1658	COG2151	metal-sulfur cluster biosynthetic enzyme
AX27061_1659	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AX27061_1660	COG1012	belongs to the aldehyde dehydrogenase family
AX27061_1661	COG1024	Enoyl-CoA hydratase
AX27061_1662	COG2050	protein possibly involved in aromatic compounds catabolism
AX27061_1664	COG0534	Mate efflux family protein
AX27061_1666	COG0254	rRNA binding
AX27061_1667	COG3483	tryptophan 2,3-dioxygenase activity
AX27061_1669	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AX27061_1670	COG2003	Belongs to the UPF0758 family
AX27061_1673	COG0625	glutathione transferase activity
AX27061_1674	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AX27061_1675	COG0642	Histidine kinase
AX27061_1676	COG0745	RESPONSE REGULATOR receiver
AX27061_1677	COG0523	cobalamin synthesis protein
AX27061_1678	COG0523	cobalamin synthesis protein
AX27061_1679	COG0583	DNA-binding transcription factor activity
AX27061_1680	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AX27061_1681	COG1187	pseudouridine synthase activity
AX27061_1682	COG0779	Required for maturation of 30S ribosomal subunits
AX27061_1683	COG2251	uridine kinase activity
AX27061_1683	COG0195	Participates in both transcription termination and antitermination
AX27061_1684	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AX27061_1685	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AX27061_1686	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AX27061_1691	COG3181	Tripartite tricarboxylate transporter family receptor
AX27061_1692	COG1473	amidohydrolase
AX27061_1693	COG1611	Belongs to the LOG family
AX27061_1696	COG0412	Dienelactone hydrolase
AX27061_1697	COG1283	sodium-dependent phosphate transmembrane transporter activity
AX27061_1699	COG1760	l-serine dehydratase
AX27061_1700	COG0501	Belongs to the peptidase M48B family
AX27061_1704	COG0583	DNA-binding transcription factor activity
AX27061_1705	COG3842	ATPase activity
AX27061_1707	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AX27061_1708	COG1840	ABC-type Fe3 transport system, periplasmic component
AX27061_1712	COG3181	Tripartite tricarboxylate transporter family receptor
AX27061_1714	COG1722	exodeoxyribonuclease VII activity
AX27061_1715	COG0142	geranyltranstransferase activity
AX27061_1716	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AX27061_1717	COG1469	GTP cyclohydrolase I activity
AX27061_1718	COG3739	integral membrane protein
AX27061_1719	COG0360	Binds together with S18 to 16S ribosomal RNA
AX27061_1720	COG2965	DNA replication, synthesis of RNA primer
AX27061_1721	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AX27061_1722	COG0359	binds to the 23S rRNA
AX27061_1724	COG0305	Participates in initiation and elongation during chromosome replication
AX27061_1726	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AX27061_1733	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AX27061_1744	COG0540	Belongs to the ATCase OTCase family
AX27061_1749	COG0642	Histidine kinase
AX27061_1751	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AX27061_1752	COG2137	regulation of response to DNA damage stimulus
AX27061_1753	COG0583	DNA-binding transcription factor activity
AX27061_1754	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AX27061_1757	COG0045	succinate-CoA ligase (ADP-forming) activity
AX27061_1758	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AX27061_1759	COG0861	Integral membrane protein TerC family
AX27061_1760	COG0861	Integral membrane protein TerC family
AX27061_1762	COG0181	hydroxymethylbilane synthase activity
AX27061_1766	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AX27061_1768	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_1772	COG0411	ABC transporter
AX27061_1774	COG0559	Belongs to the binding-protein-dependent transport system permease family
AX27061_1778	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AX27061_1779	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AX27061_1781	COG0436	Aminotransferase
AX27061_1785	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AX27061_1786	COG0308	aminopeptidase N
AX27061_1789	COG0312	modulator of DNA gyrase
AX27061_1790	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AX27061_1791	COG0277	FAD linked oxidase domain protein
AX27061_1792	COG0277	FAD linked oxidase domain protein
AX27061_1793	COG0277	FAD linked oxidase domain protein
AX27061_1794	COG0247	lactate metabolic process
AX27061_1795	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AX27061_1796	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AX27061_1797	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AX27061_1800	COG0583	DNA-binding transcription factor activity
AX27061_1801	COG0482	sulfurtransferase activity
AX27061_1802	COG0730	response to heat
AX27061_1803	COG0625	glutathione transferase activity
AX27061_1806	COG3909	cytochrome
AX27061_1814	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AX27061_1835	COG0697	spore germination
AX27061_1841	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
AX27061_1843	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AX27061_1844	COG0069	glutamate synthase activity
AX27061_1845	COG2391	methyltransferase activity
AX27061_1846	COG0679	Auxin Efflux Carrier
AX27061_1848	COG2153	protein acetylation
AX27061_1850	COG0557	exoribonuclease II activity
AX27061_1851	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AX27061_1853	COG3128	pkhd-type hydroxylase
AX27061_1854	COG0776	regulation of translation
AX27061_1858	COG0745	RESPONSE REGULATOR receiver
AX27061_1859	COG0642	Histidine kinase
AX27061_1860	COG3158	transport of potassium into the cell
AX27061_1861	COG0137	argininosuccinate synthase activity
AX27061_1862	COG0583	DNA-binding transcription factor activity
AX27061_1863	COG3618	amidohydrolase
AX27061_1867	COG2945	thiolester hydrolase activity
AX27061_1867	COG0596	Alpha beta hydrolase
AX27061_1868	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AX27061_1869	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AX27061_1873	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AX27061_1874	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AX27061_1876	COG3642	lipopolysaccharide core region biosynthetic process
AX27061_1878	COG3842	ATPase activity
AX27061_1879	COG1176	ABC-type spermidine putrescine transport system, permease component I
AX27061_1880	COG1177	transmembrane transport
AX27061_1884	COG1322	Protein conserved in bacteria
AX27061_1886	COG1960	acyl-CoA dehydrogenase activity
AX27061_1888	COG0704	Plays a role in the regulation of phosphate uptake
AX27061_1890	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AX27061_1891	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AX27061_1891	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AX27061_1892	COG1643	Atp-dependent helicase
AX27061_1893	COG0395	ABC-type sugar transport system, permease component
AX27061_1894	COG1116	anion transmembrane transporter activity
AX27061_1897	COG0438	transferase activity, transferring glycosyl groups
AX27061_1898	COG0726	polysaccharide deacetylase
AX27061_1901	COG0726	polysaccharide deacetylase
AX27061_1906	COG1132	(ABC) transporter
AX27061_1907	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AX27061_1907	COG0475	glutathione-regulated potassium exporter activity
AX27061_1909	COG4251	negative regulation of phosphorylation
AX27061_1909	COG5001	Diguanylate cyclase
AX27061_1909	COG3706	GGDEF domain
AX27061_1909	COG2203	Gaf domain
AX27061_1911	COG1530	ribonuclease E activity
AX27061_1913	COG2204	response regulator
AX27061_1914	COG4191	Histidine kinase
AX27061_1916	COG1301	dicarboxylic acid transport
AX27061_1917	COG0424	maF-like protein
AX27061_1918	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AX27061_1919	COG0799	negative regulation of ribosome biogenesis
AX27061_1920	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AX27061_1921	COG0408	coproporphyrinogen oxidase activity
AX27061_1922	COG0151	Belongs to the GarS family
AX27061_1924	COG0217	transcriptional regulatory protein
AX27061_1925	COG0433	COG0433 Predicted ATPase
AX27061_1926	COG0473	3-isopropylmalate dehydrogenase activity
AX27061_1928	COG2814	Major facilitator Superfamily
AX27061_1929	COG1566	PFAM secretion protein HlyD family protein
AX27061_1931	COG1846	Transcriptional regulator
AX27061_1937	COG3391	amine dehydrogenase activity
AX27061_1939	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AX27061_1944	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AX27061_1945	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AX27061_1947	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AX27061_1950	COG0187	DNA topoisomerase II activity
AX27061_1953	COG1309	transcriptional regulator
AX27061_1954	COG2311	Membrane
AX27061_1955	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AX27061_1959	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AX27061_1960	COG0662	Cupin 2, conserved barrel domain protein
AX27061_1961	COG5285	phytanoyl-CoA dioxygenase
AX27061_1962	COG0633	Ferredoxin
AX27061_1962	COG3217	Mosc domain protein beta barrel domain protein
AX27061_1963	COG2076	Multidrug Resistance protein
AX27061_1964	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AX27061_1966	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AX27061_1969	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AX27061_1970	COG0425	Belongs to the sulfur carrier protein TusA family
AX27061_1972	COG0228	four-way junction DNA binding
AX27061_1973	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AX27061_1974	COG0336	Belongs to the RNA methyltransferase TrmD family
AX27061_1975	COG1396	sequence-specific DNA binding
AX27061_1976	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AX27061_1977	COG0765	amino acid transport
AX27061_1979	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AX27061_1980	COG0525	valine-tRNA ligase activity
AX27061_1981	COG0105	UTP biosynthetic process
AX27061_1984	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AX27061_1985	COG0124	histidyl-tRNA synthetase
AX27061_1986	COG2976	Protein conserved in bacteria
AX27061_1987	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AX27061_1988	COG1160	GTP binding
AX27061_1989	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AX27061_1990	COG1923	regulation of RNA biosynthetic process
AX27061_1991	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AX27061_1992	COG0330	HflC and HflK could
AX27061_1993	COG0330	HflC and HflK could
AX27061_1994	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AX27061_1995	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AX27061_1996	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AX27061_1997	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AX27061_2001	COG0438	transferase activity, transferring glycosyl groups
AX27061_2003	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AX27061_2003	COG2755	lipolytic protein G-D-S-L family
AX27061_2008	COG4964	Belongs to the GSP D family
AX27061_2014	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AX27061_2016	COG1295	ribonuclease BN
AX27061_2018	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AX27061_2023	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AX27061_2024	COG4783	chaperone-mediated protein folding
AX27061_2031	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AX27061_2034	COG1538	Outer membrane efflux protein
AX27061_2035	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AX27061_2036	COG0066	3-isopropylmalate dehydratase activity
AX27061_2037	COG0473	3-isopropylmalate dehydrogenase activity
AX27061_2038	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AX27061_2042	COG0101	tRNA pseudouridine synthase activity
AX27061_2043	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AX27061_2046	COG0596	Alpha beta hydrolase
AX27061_2053	COG0129	dihydroxy-acid dehydratase activity
AX27061_2054	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AX27061_2055	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AX27061_2056	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AX27061_2057	COG1609	Transcriptional regulator
AX27061_2061	COG4172	Belongs to the ABC transporter superfamily
AX27061_2062	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AX27061_2063	COG0601	transmembrane transport
AX27061_2065	COG1012	belongs to the aldehyde dehydrogenase family
AX27061_2072	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AX27061_2073	COG2197	response regulator
AX27061_2076	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AX27061_2077	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AX27061_2078	COG0189	ligase activity
AX27061_2080	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AX27061_2081	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AX27061_2082	COG0004	ammonium transporteR
AX27061_2083	COG0347	Belongs to the P(II) protein family
AX27061_2085	COG2960	long-chain fatty acid transporting porin activity
AX27061_2086	COG0606	chelatase, subunit chli
AX27061_2088	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AX27061_2089	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AX27061_2090	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AX27061_2091	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AX27061_2091	COG0072	phenylalanine-tRNA ligase activity
AX27061_2092	COG0776	regulation of translation
AX27061_2101	COG0384	phenazine biosynthesis protein PhzF
AX27061_2102	COG0456	acetyltransferase
AX27061_2109	COG1522	sequence-specific DNA binding
AX27061_2115	COG0583	DNA-binding transcription factor activity
AX27061_2116	COG3181	Tripartite tricarboxylate transporter family receptor
AX27061_2121	COG1116	anion transmembrane transporter activity
AX27061_2127	COG5265	(ABC) transporter
AX27061_2128	COG0656	L-ascorbic acid biosynthetic process
AX27061_2131	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AX27061_2133	COG4977	sequence-specific DNA binding
AX27061_2133	COG1917	Cupin 2, conserved barrel domain protein
AX27061_2134	COG2223	nitrite transmembrane transporter activity
AX27061_2136	COG1215	transferase activity, transferring glycosyl groups
AX27061_2137	COG0726	polysaccharide deacetylase
AX27061_2137	COG1649	PFAM Uncharacterised BCR, COG1649
AX27061_2138	COG0457	Tetratricopeptide repeat
AX27061_2139	COG3706	GGDEF domain
AX27061_2144	COG1610	YqeY-like protein
AX27061_2145	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AX27061_2146	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_2154	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AX27061_2156	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AX27061_2157	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AX27061_2161	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AX27061_2161	COG1017	nitric oxide dioxygenase activity
AX27061_2163	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AX27061_2164	COG0697	spore germination
AX27061_2165	COG0506	proline dehydrogenase activity
AX27061_2168	COG0583	DNA-binding transcription factor activity
AX27061_2169	COG0583	DNA-binding transcription factor activity
AX27061_2171	COG0625	glutathione transferase activity
AX27061_2174	COG2814	Major facilitator Superfamily
AX27061_2175	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AX27061_2178	COG1960	acyl-CoA dehydrogenase activity
AX27061_2179	COG0318	PFAM AMP-dependent synthetase and ligase
AX27061_2185	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AX27061_2187	COG3245	cytochrome
AX27061_2188	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AX27061_2191	COG1280	lysine exporter protein (LysE YggA)
AX27061_2194	COG0697	spore germination
AX27061_2195	COG0697	spore germination
AX27061_2198	COG0534	Mate efflux family protein
AX27061_2199	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AX27061_2200	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_2202	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AX27061_2203	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AX27061_2205	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_2212	COG2207	Transcriptional regulator
AX27061_2214	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_2215	COG3181	Tripartite tricarboxylate transporter family receptor
AX27061_2216	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AX27061_2217	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AX27061_2219	COG1304	FMN binding
AX27061_2223	COG3712	iron ion homeostasis
AX27061_2224	COG1595	DNA-templated transcription, initiation
AX27061_2228	COG3121	Chaperone
AX27061_2229	COG2205	protein histidine kinase activity
AX27061_2229	COG0784	Response regulator, receiver
AX27061_2229	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AX27061_2229	COG2198	Histidine kinase
AX27061_2230	COG2205	protein histidine kinase activity
AX27061_2230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AX27061_2231	COG5001	Diguanylate cyclase
AX27061_2231	COG1716	ATPase activity
AX27061_2235	COG3088	subunit of a heme lyase
AX27061_2236	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AX27061_2238	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AX27061_2242	COG4133	protoheme IX ABC transporter activity
AX27061_2245	COG3381	protein complex oligomerization
AX27061_2249	COG4235	cytochrome complex assembly
AX27061_2251	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AX27061_2253	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AX27061_2257	COG4133	protoheme IX ABC transporter activity
AX27061_2258	COG3005	denitrification pathway
AX27061_2259	COG3043	anaerobic respiration
AX27061_2263	COG3246	L-lysine catabolic process to acetate
AX27061_2264	COG1250	3-hydroxyacyl-CoA dehydrogenase
AX27061_2265	COG0583	DNA-binding transcription factor activity
AX27061_2267	COG0129	dihydroxy-acid dehydratase activity
AX27061_2268	COG3181	Tripartite tricarboxylate transporter family receptor
AX27061_2269	COG5001	Diguanylate cyclase
AX27061_2270	COG1024	Enoyl-CoA hydratase
AX27061_2279	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
AX27061_2280	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_2281	COG0583	DNA-binding transcription factor activity
AX27061_2282	COG2610	gluconate transmembrane transporter activity
AX27061_2290	COG0235	Class ii aldolase
AX27061_2291	COG0477	Major facilitator Superfamily
AX27061_2295	COG0318	PFAM AMP-dependent synthetase and ligase
AX27061_2304	COG1280	lysine exporter protein (LysE YggA)
AX27061_2305	COG5265	(ABC) transporter
AX27061_2308	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AX27061_2311	COG0318	PFAM AMP-dependent synthetase and ligase
AX27061_2312	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_2318	COG1132	(ABC) transporter
AX27061_2319	COG0583	DNA-binding transcription factor activity
AX27061_2322	COG0583	DNA-binding transcription factor activity
AX27061_2324	COG0583	DNA-binding transcription factor activity
AX27061_2329	COG2226	methyltransferase
AX27061_2331	COG2814	Major facilitator Superfamily
AX27061_2332	COG0154	amidase activity
AX27061_2341	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_2342	COG2186	Transcriptional regulator
AX27061_2344	COG1012	belongs to the aldehyde dehydrogenase family
AX27061_2345	COG0307	riboflavin synthase, alpha
AX27061_2347	COG2271	Major facilitator Superfamily
AX27061_2349	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AX27061_2352	COG0789	Transcriptional regulator
AX27061_2357	COG4774	siderophore transport
AX27061_2359	COG0022	dehydrogenase e1 component
AX27061_2363	COG0165	Argininosuccinate lyase
AX27061_2365	COG0668	transmembrane transport
AX27061_2385	COG0583	DNA-binding transcription factor activity
AX27061_2387	COG0747	negative chemotaxis
AX27061_2388	COG0601	transmembrane transport
AX27061_2390	COG4172	Belongs to the ABC transporter superfamily
AX27061_2391	COG4681	YaeQ
AX27061_2394	COG0477	Major facilitator Superfamily
AX27061_2396	COG3161	chorismate lyase activity
AX27061_2397	COG1187	pseudouridine synthase activity
AX27061_2402	COG1538	Outer membrane efflux protein
AX27061_2404	COG1999	signal sequence binding
AX27061_2406	COG0339	signal peptide processing
AX27061_2408	COG4566	intracellular signal transduction
AX27061_2410	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AX27061_2411	COG0508	dehydrogenase complex catalyzes the overall conversion of
AX27061_2412	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AX27061_2414	COG0583	DNA-binding transcription factor activity
AX27061_2418	COG4797	methyltransferase
AX27061_2418	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AX27061_2419	COG1191	sigma factor activity
AX27061_2423	COG1360	Flagellar Motor Protein
AX27061_2426	COG0835	chemotaxis
AX27061_2427	COG0840	transmembrane signaling receptor activity
AX27061_2428	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AX27061_2429	COG2201	protein-glutamate methylesterase activity
AX27061_2430	COG0745	RESPONSE REGULATOR receiver
AX27061_2431	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AX27061_2432	COG0840	transmembrane signaling receptor activity
AX27061_2437	COG2747	anti-sigma28 factor FlgM
AX27061_2439	COG1815	bacterial-type flagellum-dependent cell motility
AX27061_2440	COG1558	bacterial-type flagellum-dependent cell motility
AX27061_2441	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AX27061_2442	COG1749	Flagellar hook protein flgE
AX27061_2443	COG4787	bacterial-type flagellum-dependent cell motility
AX27061_2444	COG4786	Flagellar basal body rod
AX27061_2445	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AX27061_2446	COG1706	bacterial-type flagellum-dependent cell motility
AX27061_2448	COG1256	bacterial-type flagellum assembly
AX27061_2453	COG0840	transmembrane signaling receptor activity
AX27061_2454	COG0840	transmembrane signaling receptor activity
AX27061_2458	COG3190	flagellar
AX27061_2459	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AX27061_2461	COG1580	Controls the rotational direction of flagella during chemotaxis
AX27061_2467	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AX27061_2468	COG1766	The M ring may be actively involved in energy transduction
AX27061_2469	COG1677	Flagellar hook-basal body complex protein FliE
AX27061_2471	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AX27061_2475	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AX27061_2476	COG1334	flagellar protein FlaG
AX27061_2477	COG1414	Transcriptional regulator
AX27061_2479	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AX27061_2480	COG3181	Tripartite tricarboxylate transporter family receptor
AX27061_2482	COG0285	dihydrofolate synthase activity
AX27061_2486	COG1451	nucleotide metabolic process
AX27061_2487	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AX27061_2489	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AX27061_2490	COG0024	Methionine aminopeptidase
AX27061_2491	COG0052	Belongs to the universal ribosomal protein uS2 family
AX27061_2492	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AX27061_2493	COG0528	UMP kinase activity
AX27061_2494	COG0233	cytoplasmic translational termination
AX27061_2495	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AX27061_2497	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AX27061_2498	COG0750	zinc metalloprotease
AX27061_2499	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AX27061_2500	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AX27061_2501	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AX27061_2502	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AX27061_2504	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AX27061_2505	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AX27061_2506	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AX27061_2508	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AX27061_2510	COG2169	Transcriptional regulator
AX27061_2510	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AX27061_2511	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AX27061_2511	COG0519	Catalyzes the synthesis of GMP from XMP
AX27061_2514	COG3706	GGDEF domain
AX27061_2514	COG0745	RESPONSE REGULATOR receiver
AX27061_2515	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AX27061_2516	COG2867	negative regulation of translational initiation
AX27061_2519	COG1024	Enoyl-CoA hydratase
AX27061_2519	COG1250	3-hydroxyacyl-CoA dehydrogenase
AX27061_2524	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AX27061_2525	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AX27061_2526	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AX27061_2527	COG0084	hydrolase, TatD family'
AX27061_2530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AX27061_2532	COG1126	abc transporter atp-binding protein
AX27061_2533	COG0010	Belongs to the arginase family
AX27061_2535	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AX27061_2537	COG0095	Lipoate-protein ligase
AX27061_2540	COG0625	glutathione transferase activity
AX27061_2542	COG1522	sequence-specific DNA binding
AX27061_2543	COG0386	Belongs to the glutathione peroxidase family
AX27061_2544	COG2814	Major facilitator Superfamily
AX27061_2548	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AX27061_2550	COG0840	transmembrane signaling receptor activity
AX27061_2552	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AX27061_2559	COG1902	pentaerythritol trinitrate reductase activity
AX27061_2565	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AX27061_2568	COG0842	Transport permease protein
AX27061_2569	COG1131	(ABC) transporter
AX27061_2572	COG2130	NADP-dependent
AX27061_2577	COG3842	ATPase activity
AX27061_2578	COG3842	ATPase activity
AX27061_2580	COG0395	ABC-type sugar transport system, permease component
AX27061_2590	COG0346	lactoylglutathione lyase activity
AX27061_2591	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AX27061_2595	COG3634	alkyl hydroperoxide reductase activity
AX27061_2596	COG1959	2 iron, 2 sulfur cluster binding
AX27061_2597	COG1960	acyl-CoA dehydrogenase activity
AX27061_2604	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AX27061_2605	COG0420	3'-5' exonuclease activity
AX27061_2614	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AX27061_2614	COG2111	Na H antiporter
AX27061_2615	COG1006	Multisubunit Na H antiporter MnhC subunit
AX27061_2616	COG0651	ATP synthesis coupled electron transport
AX27061_2617	COG1863	multisubunit Na H antiporter MnhE subunit
AX27061_2618	COG2212	antiporter activity
AX27061_2619	COG1320	monovalent cation:proton antiporter activity
AX27061_2622	COG0590	tRNA wobble adenosine to inosine editing
AX27061_2623	COG1619	proteins homologs of microcin C7 resistance protein MccF
AX27061_2624	COG0488	(ABC) transporter
AX27061_2626	COG2814	Major facilitator Superfamily
AX27061_2632	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AX27061_2633	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AX27061_2636	COG2252	PERMEase
AX27061_2637	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AX27061_2638	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AX27061_2639	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AX27061_2640	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AX27061_2645	COG0583	DNA-binding transcription factor activity
AX27061_2646	COG2814	Major facilitator Superfamily
AX27061_2647	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AX27061_2648	COG0789	Transcriptional regulator
AX27061_2651	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AX27061_2651	COG0678	peroxiredoxin activity
AX27061_2653	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AX27061_2654	COG0584	glycerophosphoryl diester phosphodiesterase
AX27061_2656	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AX27061_2658	COG4181	ATPase activity
AX27061_2660	COG1178	ABC-type Fe3 transport system permease component
AX27061_2661	COG3842	ATPase activity
AX27061_2663	COG0583	DNA-binding transcription factor activity
AX27061_2664	COG0560	Phosphoserine phosphatase
AX27061_2667	COG0583	DNA-binding transcription factor activity
AX27061_2670	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AX27061_2673	COG0583	DNA-binding transcription factor activity
AX27061_2674	COG4336	lyase activity
AX27061_2676	COG0559	Belongs to the binding-protein-dependent transport system permease family
AX27061_2678	COG0411	ABC transporter
AX27061_2680	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AX27061_2684	COG2816	NAD+ diphosphatase activity
AX27061_2691	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AX27061_2692	COG0765	amino acid transport
AX27061_2693	COG1126	abc transporter atp-binding protein
AX27061_2694	COG1335	isochorismatase
AX27061_2696	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AX27061_2697	COG1758	RNA polymerase activity
AX27061_2698	COG0194	GDP metabolic process
AX27061_2699	COG3258	Cytochrome c
AX27061_2700	COG2863	cytochrome
AX27061_2701	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_2702	COG2831	hemolysin activation secretion protein
AX27061_2703	COG3210	domain, Protein
AX27061_2704	COG0791	NLP P60 protein
AX27061_2707	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AX27061_2709	COG0833	amino acid
AX27061_2710	COG1561	YicC-like family, N-terminal region
AX27061_2711	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AX27061_2713	COG1960	acyl-CoA dehydrogenase activity
AX27061_2716	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AX27061_2717	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AX27061_2719	COG3852	Histidine kinase
AX27061_2720	COG2204	response regulator
AX27061_2721	COG0583	DNA-binding transcription factor activity
AX27061_2722	COG1741	Belongs to the pirin family
AX27061_2723	COG1741	Belongs to the pirin family
AX27061_2724	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AX27061_2725	COG1690	Belongs to the RtcB family
AX27061_2726	COG3181	Tripartite tricarboxylate transporter family receptor
AX27061_2727	COG3842	ATPase activity
AX27061_2728	COG4149	molybdate abc transporter
AX27061_2729	COG1840	ABC-type Fe3 transport system, periplasmic component
AX27061_2731	COG3181	Tripartite tricarboxylate transporter family receptor
AX27061_2734	COG0583	DNA-binding transcription factor activity
AX27061_2736	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AX27061_2738	COG0783	Belongs to the Dps family
AX27061_2740	COG0457	Tetratricopeptide repeat
AX27061_2741	COG0438	transferase activity, transferring glycosyl groups
AX27061_2746	COG4783	chaperone-mediated protein folding
AX27061_2746	COG1560	Kdo2-lipid A biosynthetic process
AX27061_2747	COG3866	Pectate lyase
AX27061_2751	COG0745	RESPONSE REGULATOR receiver
AX27061_2752	COG2205	protein histidine kinase activity
AX27061_2755	COG3842	ATPase activity
AX27061_2756	COG0395	ABC-type sugar transport system, permease component
AX27061_2757	COG1175	transmembrane transport
AX27061_2758	COG1653	transport
AX27061_2760	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AX27061_2762	COG0559	Belongs to the binding-protein-dependent transport system permease family
AX27061_2765	COG0410	ABC transporter
AX27061_2767	COG1794	racemase activity, acting on amino acids and derivatives
AX27061_2768	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AX27061_2770	COG0583	DNA-binding transcription factor activity
AX27061_2771	COG0625	glutathione transferase activity
AX27061_2772	COG2133	pyrroloquinoline quinone binding
AX27061_2774	COG0697	spore germination
AX27061_2775	COG2363	Small membrane protein
AX27061_2779	COG0010	Belongs to the arginase family
AX27061_2780	COG1464	Belongs to the NlpA lipoprotein family
AX27061_2781	COG0745	RESPONSE REGULATOR receiver
AX27061_2781	COG3706	GGDEF domain
AX27061_2782	COG2814	Major facilitator Superfamily
AX27061_2784	COG1408	metallophosphoesterase
AX27061_2786	COG0688	phosphatidylethanolamine metabolic process
AX27061_2787	COG0488	(ABC) transporter
AX27061_2792	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AX27061_2793	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AX27061_2794	COG5001	Diguanylate cyclase
AX27061_2794	COG3300	MHYT domain
AX27061_2798	COG2814	Major facilitator Superfamily
AX27061_2802	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AX27061_2803	COG2204	response regulator
AX27061_2809	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_2813	COG0693	protein deglycase activity
AX27061_2817	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AX27061_2819	COG1289	transmembrane transporter activity
AX27061_2820	COG5001	Diguanylate cyclase
AX27061_2820	COG3300	MHYT domain
AX27061_2822	COG4774	siderophore transport
AX27061_2830	COG1253	flavin adenine dinucleotide binding
AX27061_2832	COG2205	protein histidine kinase activity
AX27061_2867	COG3706	GGDEF domain
AX27061_2868	COG0789	Transcriptional regulator
AX27061_2870	COG3706	GGDEF domain
AX27061_2876	COG1116	anion transmembrane transporter activity
AX27061_2877	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AX27061_2878	COG4521	taurine ABC transporter
AX27061_2884	COG0793	Belongs to the peptidase S41A family
AX27061_2888	COG0628	permease
AX27061_2890	COG1619	proteins homologs of microcin C7 resistance protein MccF
AX27061_2893	COG0531	amino acid
AX27061_2896	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AX27061_2897	COG4608	Belongs to the ABC transporter superfamily
AX27061_2898	COG0444	Belongs to the ABC transporter superfamily
AX27061_2900	COG0601	transmembrane transport
AX27061_2901	COG0747	negative chemotaxis
AX27061_2903	COG0251	oxidation-reduction process
AX27061_2907	COG0179	Fumarylacetoacetate (FAA) hydrolase
AX27061_2910	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AX27061_2913	COG0446	pyridine nucleotide-disulphide oxidoreductase
AX27061_2915	COG3971	2-oxopent-4-enoate hydratase activity
AX27061_2921	COG0625	glutathione transferase activity
AX27061_2924	COG0477	Major facilitator Superfamily
AX27061_2926	COG0579	oxidoreductase
AX27061_2929	COG0625	glutathione transferase activity
AX27061_2932	COG0431	NADPH-dependent FMN reductase
AX27061_2934	COG0798	PFAM Bile acid sodium symporter
AX27061_2936	COG0640	Transcriptional regulator
AX27061_2939	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AX27061_2943	COG1126	abc transporter atp-binding protein
AX27061_2944	COG0765	amino acid transport
AX27061_2945	COG4597	amino acid ABC transporter
AX27061_2946	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AX27061_2947	COG0626	cystathionine gamma-synthase activity
AX27061_2948	COG0583	DNA-binding transcription factor activity
AX27061_2952	COG0444	Belongs to the ABC transporter superfamily
AX27061_2954	COG0601	transmembrane transport
AX27061_2955	COG0747	negative chemotaxis
AX27061_2957	COG0583	DNA-binding transcription factor activity
AX27061_2958	COG1335	isochorismatase
AX27061_2959	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AX27061_2962	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AX27061_2963	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AX27061_2966	COG0519	Catalyzes the synthesis of GMP from XMP
AX27061_2966	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AX27061_2968	COG1276	copper resistance
AX27061_2972	COG3181	Tripartite tricarboxylate transporter family receptor
AX27061_2973	COG3386	PFAM SMP-30 Gluconolaconase
AX27061_2974	COG2721	sulfolactate sulfo-lyase activity
AX27061_2978	COG0745	RESPONSE REGULATOR receiver
AX27061_2980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AX27061_2981	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
AX27061_2982	COG3842	ATPase activity
AX27061_2983	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AX27061_2986	COG0586	Pfam SNARE associated Golgi protein
AX27061_2987	COG0390	transport system, permease component
AX27061_2989	COG3486	L-lysine 6-monooxygenase (NADPH) activity
AX27061_2998	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AX27061_2999	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AX27061_3000	COG1120	ATPase activity
AX27061_3001	COG1126	abc transporter atp-binding protein
AX27061_3002	COG0765	amino acid transport
AX27061_3004	COG2070	2-Nitropropane dioxygenase
AX27061_3005	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AX27061_3007	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AX27061_3012	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AX27061_3013	COG0583	DNA-binding transcription factor activity
AX27061_3015	COG1846	Transcriptional regulator
AX27061_3017	COG4191	Histidine kinase
AX27061_3018	COG4566	intracellular signal transduction
AX27061_3022	COG0583	DNA-binding transcription factor activity
AX27061_3028	COG0765	amino acid transport
AX27061_3034	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AX27061_3039	COG0251	oxidation-reduction process
AX27061_3047	COG4948	Mandelate Racemase Muconate Lactonizing
AX27061_3049	COG1802	Transcriptional regulator
AX27061_3050	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AX27061_3053	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AX27061_3058	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AX27061_3059	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AX27061_3060	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AX27061_3060	COG1116	anion transmembrane transporter activity
AX27061_3067	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AX27061_3068	COG4597	amino acid ABC transporter
AX27061_3072	COG2197	response regulator
AX27061_3073	COG3850	Histidine kinase
AX27061_3075	COG1763	Mo-molybdopterin cofactor biosynthetic process
AX27061_3076	COG0288	reversible hydration of carbon dioxide
AX27061_3077	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AX27061_3078	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AX27061_3079	COG2181	nitrate reductase activity
AX27061_3080	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AX27061_3081	COG1140	nitrate reductase beta subunit
AX27061_3082	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AX27061_3084	COG2223	nitrite transmembrane transporter activity
AX27061_3088	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AX27061_3093	COG0583	DNA-binding transcription factor activity
AX27061_3095	COG3181	Tripartite tricarboxylate transporter family receptor
AX27061_3102	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AX27061_3106	COG2070	2-Nitropropane dioxygenase
AX27061_3108	COG3848	Pyruvate phosphate dikinase
AX27061_3108	COG0574	Belongs to the PEP-utilizing enzyme family
AX27061_3110	COG0745	RESPONSE REGULATOR receiver
AX27061_3111	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
AX27061_3112	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AX27061_3114	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AX27061_3115	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AX27061_3120	COG0783	Belongs to the Dps family
AX27061_3126	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AX27061_3127	COG0697	spore germination
AX27061_3128	COG2879	small protein
AX27061_3129	COG1966	Carbon starvation protein
AX27061_3134	COG0583	DNA-binding transcription factor activity
AX27061_3135	COG4521	taurine ABC transporter
AX27061_3136	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AX27061_3137	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AX27061_3139	COG3712	iron ion homeostasis
AX27061_3140	COG1595	DNA-templated transcription, initiation
AX27061_3141	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AX27061_3144	COG0235	Class ii aldolase
AX27061_3145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AX27061_3147	COG0523	cobalamin synthesis protein
AX27061_3148	COG1228	amidohydrolase
AX27061_3149	COG4172	Belongs to the ABC transporter superfamily
AX27061_3150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AX27061_3151	COG0601	transmembrane transport
AX27061_3152	COG0747	negative chemotaxis
AX27061_3156	COG1414	Transcriptional regulator
AX27061_3157	COG0513	Belongs to the DEAD box helicase family
AX27061_3158	COG0602	queuosine metabolic process
AX27061_3159	COG0720	synthase
AX27061_3161	COG1289	transmembrane transporter activity
AX27061_3163	COG1566	PFAM secretion protein HlyD family protein
AX27061_3166	COG0028	Belongs to the TPP enzyme family
AX27061_3168	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_3170	COG0400	carboxylic ester hydrolase activity
AX27061_3172	COG0833	amino acid
AX27061_3177	COG0587	DNA-directed DNA polymerase activity
AX27061_3179	COG0789	Transcriptional regulator
AX27061_3181	COG0667	Aldo Keto reductase
AX27061_3183	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AX27061_3185	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_3186	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AX27061_3190	COG3038	cytochrome b561
AX27061_3193	COG0840	transmembrane signaling receptor activity
AX27061_3207	COG2764	glyoxalase bleomycin resistance protein dioxygenase
AX27061_3211	COG4774	siderophore transport
AX27061_3212	COG2345	Transcriptional regulator
AX27061_3214	COG1414	Transcriptional regulator
AX27061_3216	COG0477	Major facilitator Superfamily
AX27061_3217	COG0667	Aldo Keto reductase
AX27061_3219	COG3181	Tripartite tricarboxylate transporter family receptor
AX27061_3220	COG1309	transcriptional regulator
AX27061_3224	COG1683	Conserved Protein
AX27061_3226	COG2207	Transcriptional regulator
AX27061_3230	COG2885	chlorophyll binding
AX27061_3230	COG3047	cAMP biosynthetic process
AX27061_3233	COG3795	YCII-related domain
AX27061_3234	COG3795	YCII-related domain
AX27061_3236	COG4941	Belongs to the sigma-70 factor family
AX27061_3238	COG0697	spore germination
AX27061_3240	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AX27061_3242	COG0583	DNA-binding transcription factor activity
AX27061_3248	COG1846	Transcriptional regulator
AX27061_3249	COG3541	Predicted nucleotidyltransferase
AX27061_3253	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AX27061_3261	COG1360	Flagellar Motor Protein
AX27061_3263	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
AX27061_3269	COG3501	Rhs element vgr protein
AX27061_3281	COG3501	Rhs element vgr protein
AX27061_3297	COG0024	Methionine aminopeptidase
AX27061_3299	COG0625	glutathione transferase activity
AX27061_3300	COG2032	superoxide dismutase activity
AX27061_3301	COG2733	membrane
AX27061_3303	COG0148	phosphopyruvate hydratase activity
AX27061_3308	COG0583	DNA-binding transcription factor activity
AX27061_3310	COG1024	Enoyl-CoA hydratase
AX27061_3310	COG1250	3-hydroxyacyl-CoA dehydrogenase
AX27061_3311	COG0183	Belongs to the thiolase family
AX27061_3312	COG1960	acyl-CoA dehydrogenase activity
AX27061_3313	COG1960	acyl-CoA dehydrogenase activity
AX27061_3314	COG0318	PFAM AMP-dependent synthetase and ligase
AX27061_3316	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AX27061_3319	COG0583	DNA-binding transcription factor activity
AX27061_3321	COG1846	Transcriptional regulator
AX27061_3322	COG0477	Major facilitator Superfamily
AX27061_3324	COG2080	2 iron, 2 sulfur cluster binding
AX27061_3326	COG0596	Alpha beta hydrolase
AX27061_3327	COG2309	aminopeptidase activity
AX27061_3328	COG1335	isochorismatase
AX27061_3329	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AX27061_3329	COG2010	Cytochrome c
AX27061_3331	COG1522	sequence-specific DNA binding
AX27061_3332	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AX27061_3333	COG3842	ATPase activity
AX27061_3334	COG1840	ABC-type Fe3 transport system, periplasmic component
AX27061_3335	COG4149	molybdate abc transporter
AX27061_3336	COG3706	GGDEF domain
AX27061_3336	COG5001	Diguanylate cyclase
AX27061_3336	COG4251	negative regulation of phosphorylation
AX27061_3336	COG2203	Gaf domain
AX27061_3337	COG2201	protein-glutamate methylesterase activity
AX27061_3341	COG0840	transmembrane signaling receptor activity
AX27061_3342	COG0154	amidase activity
AX27061_3345	COG0583	DNA-binding transcription factor activity
AX27061_3351	COG0456	acetyltransferase
AX27061_3354	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_3368	COG0165	Argininosuccinate lyase
AX27061_3371	COG0583	DNA-binding transcription factor activity
AX27061_3374	COG2205	protein histidine kinase activity
AX27061_3378	COG2207	Transcriptional regulator
AX27061_3379	COG2267	carboxylic ester hydrolase activity
AX27061_3381	COG4221	oxidoreductase activity
AX27061_3382	COG2207	Transcriptional regulator
AX27061_3388	COG0640	Transcriptional regulator
AX27061_3389	COG0640	Transcriptional regulator
AX27061_3391	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AX27061_3392	COG0583	DNA-binding transcription factor activity
AX27061_3393	COG0431	NADPH-dependent FMN reductase
AX27061_3395	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AX27061_3398	COG4264	IucA IucC family
AX27061_3401	COG3328	transposase activity
AX27061_3405	COG0633	Ferredoxin
AX27061_3406	COG0789	Transcriptional regulator
AX27061_3408	COG0640	Transcriptional regulator
AX27061_3409	COG2814	Major facilitator Superfamily
AX27061_3410	COG1937	Protein conserved in bacteria
AX27061_3411	COG1230	cation diffusion facilitator family transporter
AX27061_3412	COG0640	Transcriptional regulator
AX27061_3415	COG1538	Outer membrane efflux protein
AX27061_3417	COG2814	Major facilitator Superfamily
AX27061_3420	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AX27061_3425	COG1192	Involved in chromosome partitioning
AX27061_3431	COG5489	Protein of unknown function (DUF736)
AX27061_3433	COG1475	DNA binding
AX27061_3443	COG0582	viral genome integration into host DNA
AX27061_3445	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AX27061_3452	COG0798	PFAM Bile acid sodium symporter
AX27061_3459	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AX27061_3459	COG0519	Catalyzes the synthesis of GMP from XMP
AX27061_3465	COG0583	DNA-binding transcription factor activity
AX27061_3467	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AX27061_3472	COG0583	DNA-binding transcription factor activity
AX27061_3473	COG3181	Tripartite tricarboxylate transporter family receptor
AX27061_3525	COG2974	May be involved in recombination
AX27061_3526	COG0419	ATPase involved in DNA repair
AX27061_3537	COG2072	flavoprotein involved in K transport
AX27061_3538	COG0601	transmembrane transport
AX27061_3539	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AX27061_3541	COG4608	Belongs to the ABC transporter superfamily
AX27061_3542	COG0747	negative chemotaxis
AX27061_3545	COG0583	DNA-binding transcription factor activity
AX27061_3546	COG3181	Tripartite tricarboxylate transporter family receptor
AX27061_3547	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AX27061_3548	COG3181	Tripartite tricarboxylate transporter family receptor
AX27061_3555	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AX27061_3560	COG0583	DNA-binding transcription factor activity
AX27061_3569	COG5001	Diguanylate cyclase
AX27061_3570	COG4774	siderophore transport
AX27061_3571	COG4774	siderophore transport
AX27061_3574	COG0583	DNA-binding transcription factor activity
AX27061_3584	COG1953	Uracil, thiamine, allantoin
AX27061_3591	COG0583	DNA-binding transcription factor activity
AX27061_3592	COG0784	Response regulator, receiver
AX27061_3592	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AX27061_3592	COG2198	Histidine kinase
AX27061_3592	COG2205	protein histidine kinase activity
AX27061_3599	COG3181	Tripartite tricarboxylate transporter family receptor
AX27061_3600	COG0583	DNA-binding transcription factor activity
AX27061_3601	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AX27061_3603	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_3605	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AX27061_3607	COG0583	DNA-binding transcription factor activity
AX27061_3610	COG0642	Histidine kinase
AX27061_3611	COG0745	RESPONSE REGULATOR receiver
AX27061_3615	COG1595	DNA-templated transcription, initiation
AX27061_3616	COG3712	iron ion homeostasis
AX27061_3617	COG4774	siderophore transport
AX27061_3618	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AX27061_3618	COG0047	phosphoribosylformylglycinamidine synthase activity
AX27061_3621	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AX27061_3623	COG0613	PHP domain protein
AX27061_3626	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AX27061_3628	COG0583	DNA-binding transcription factor activity
AX27061_3630	COG0583	DNA-binding transcription factor activity
AX27061_3631	COG0477	Major facilitator Superfamily
AX27061_3632	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AX27061_3634	COG0159	tryptophan synthase activity
AX27061_3638	COG0277	FAD linked oxidase domain protein
AX27061_3639	COG3181	Tripartite tricarboxylate transporter family receptor
AX27061_3648	COG2149	membrane
AX27061_3650	COG3093	addiction module antidote protein HigA
AX27061_3655	COG2249	NAD(P)H dehydrogenase (quinone) activity
AX27061_3657	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AX27061_3658	COG0459	protein refolding
AX27061_3665	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AX27061_3666	COG0714	Associated with various cellular activities
AX27061_3670	COG2304	oxidoreductase activity
AX27061_3673	COG3119	arylsulfatase activity
AX27061_3675	COG1280	lysine exporter protein (LysE YggA)
AX27061_3681	COG0633	Ferredoxin
AX27061_3682	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_3683	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_3684	COG4133	protoheme IX ABC transporter activity
AX27061_3685	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AX27061_3690	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AX27061_3693	COG4604	ABC transporter, ATP-binding protein
AX27061_3694	COG4605	iron ion homeostasis
AX27061_3695	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AX27061_3696	COG4607	ABC-type enterochelin transport system periplasmic component
AX27061_3697	COG4771	TonB-dependent receptor
AX27061_3698	COG0745	RESPONSE REGULATOR receiver
AX27061_3700	COG0084	hydrolase, TatD family'
AX27061_3701	COG1136	(ABC) transporter
AX27061_3705	COG2271	Major facilitator Superfamily
AX27061_3707	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AX27061_3708	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_3709	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AX27061_3713	COG3135	benzoate transporter
AX27061_3714	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AX27061_3715	COG1309	transcriptional regulator
AX27061_3716	COG0183	Belongs to the thiolase family
AX27061_3717	COG1022	Amp-dependent synthetase and ligase
AX27061_3718	COG0410	ABC transporter
AX27061_3723	COG1024	Enoyl-CoA hydratase
AX27061_3725	COG1803	Methylglyoxal synthase
AX27061_3726	COG2975	iron-sulfur cluster assembly
AX27061_3727	COG0633	Ferredoxin
AX27061_3728	COG0443	Heat shock 70 kDa protein
AX27061_3729	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AX27061_3730	COG0316	Belongs to the HesB IscA family
AX27061_3731	COG0822	iron-sulfur transferase activity
AX27061_3732	COG1104	cysteine desulfurase activity
AX27061_3734	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AX27061_3735	COG0556	nucleotide-excision repair
AX27061_3738	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AX27061_3739	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AX27061_3740	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AX27061_3741	COG0740	serine-type endopeptidase activity
AX27061_3742	COG0544	peptidyl-prolyl cis-trans isomerase activity
AX27061_3743	COG0501	Belongs to the peptidase M48B family
AX27061_3745	COG1278	Cold shock
AX27061_3747	COG1278	Cold shock
AX27061_3752	COG0251	oxidation-reduction process
AX27061_3754	COG0583	DNA-binding transcription factor activity
AX27061_3761	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AX27061_3764	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AX27061_3766	COG0277	FAD linked oxidase domain protein
AX27061_3768	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AX27061_3769	COG2814	Major facilitator Superfamily
AX27061_3798	COG0740	serine-type endopeptidase activity
AX27061_3815	COG3685	Protein conserved in bacteria
AX27061_3816	COG3546	catalase activity
AX27061_3820	COG1475	DNA binding
AX27061_3830	COG2171	N-acyltransferase activity
AX27061_3832	COG2890	protein-(glutamine-N5) methyltransferase activity
AX27061_3833	COG0488	(ABC) transporter
AX27061_3836	COG4771	TonB-dependent receptor
AX27061_3837	COG4771	TonB-dependent receptor
AX27061_3840	COG4771	TonB-dependent receptor
AX27061_3842	COG1858	cytochrome C peroxidase
AX27061_3844	COG0210	DNA helicase
AX27061_3847	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AX27061_3847	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AX27061_3848	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AX27061_3849	COG0196	riboflavin kinase activity
AX27061_3850	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AX27061_3851	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AX27061_3852	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AX27061_3862	COG1902	pentaerythritol trinitrate reductase activity
AX27061_3863	COG1126	abc transporter atp-binding protein
AX27061_3864	COG0765	amino acid transport
AX27061_3865	COG0765	amino acid transport
AX27061_3866	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AX27061_3869	COG1764	response to oxidative stress
AX27061_3872	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AX27061_3873	COG0625	glutathione transferase activity
AX27061_3877	COG2271	Major facilitator Superfamily
AX27061_3879	COG0411	ABC transporter
AX27061_3881	COG0559	Belongs to the binding-protein-dependent transport system permease family
AX27061_3884	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AX27061_3884	COG0506	proline dehydrogenase activity
AX27061_3884	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AX27061_3886	COG3008	intermembrane lipid transfer
AX27061_3887	COG2995	paraquat-inducible protein a
AX27061_3889	COG4953	penicillin-binding protein 1C
AX27061_3890	COG2373	Large extracellular alpha-helical protein
AX27061_3891	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AX27061_3892	COG1278	Cold shock
AX27061_3894	COG0183	Belongs to the thiolase family
AX27061_3896	COG0038	chloride channel
AX27061_3899	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AX27061_3902	COG1570	exodeoxyribonuclease VII activity
AX27061_3904	COG0811	peptide transport
AX27061_3906	COG1663	tetraacyldisaccharide 4'-kinase activity
AX27061_3908	COG2835	tetraacyldisaccharide 4'-kinase activity
AX27061_3909	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AX27061_3910	COG0563	adenylate kinase activity
AX27061_3912	COG0728	peptidoglycan biosynthetic process
AX27061_3914	COG0268	Binds directly to 16S ribosomal RNA
AX27061_3915	COG0583	DNA-binding transcription factor activity
AX27061_3916	COG0019	diaminopimelate decarboxylase activity
AX27061_3918	COG3181	Tripartite tricarboxylate transporter family receptor
AX27061_3919	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AX27061_3920	COG2186	Transcriptional regulator
AX27061_3922	COG3181	Tripartite tricarboxylate transporter family receptor
AX27061_3924	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AX27061_3931	COG3384	dioxygenase
AX27061_3932	COG1012	belongs to the aldehyde dehydrogenase family
AX27061_3935	COG3971	2-oxopent-4-enoate hydratase activity
AX27061_3937	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_3938	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AX27061_3939	COG1562	ergosterol biosynthetic process
AX27061_3940	COG1562	ergosterol biosynthetic process
AX27061_3942	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AX27061_3945	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AX27061_3949	COG5564	TIM-barrel signal transduction protein
AX27061_3950	COG5441	Belongs to the UPF0261 family
AX27061_3955	COG0542	response to heat
AX27061_3957	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AX27061_3959	COG0477	Major facilitator Superfamily
AX27061_3963	COG0494	nUDIX hydrolase
AX27061_3965	COG0583	DNA-binding transcription factor activity
AX27061_3966	COG0443	Heat shock 70 kDa protein
AX27061_3973	COG2814	Major facilitator Superfamily
AX27061_3975	COG3530	Putative quorum-sensing-regulated virulence factor
AX27061_3978	COG0625	glutathione transferase activity
AX27061_3983	COG3181	Tripartite tricarboxylate transporter family receptor
AX27061_3985	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AX27061_3997	COG1522	sequence-specific DNA binding
AX27061_3999	COG4172	Belongs to the ABC transporter superfamily
AX27061_4004	COG0519	Catalyzes the synthesis of GMP from XMP
AX27061_4007	COG1595	DNA-templated transcription, initiation
AX27061_4011	COG0519	Catalyzes the synthesis of GMP from XMP
AX27061_4013	COG2951	lytic endotransglycosylase activity
AX27061_4015	COG0583	DNA-binding transcription factor activity
AX27061_4016	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AX27061_4017	COG2272	Belongs to the type-B carboxylesterase lipase family
AX27061_4018	COG3181	Tripartite tricarboxylate transporter family receptor
AX27061_4019	COG1309	transcriptional regulator
AX27061_4022	COG1473	amidohydrolase
AX27061_4023	COG3181	Tripartite tricarboxylate transporter family receptor
AX27061_4026	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
AX27061_4029	COG3618	amidohydrolase
AX27061_4030	COG3181	Tripartite tricarboxylate transporter family receptor
AX27061_4037	COG2011	ABC-type metal ion transport system permease component
AX27061_4038	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AX27061_4041	COG2814	Major facilitator Superfamily
AX27061_4043	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AX27061_4044	COG1250	3-hydroxyacyl-CoA dehydrogenase
AX27061_4052	COG2837	iron assimilation
AX27061_4063	COG0583	DNA-binding transcription factor activity
AX27061_4064	COG2814	Major facilitator Superfamily
AX27061_4065	COG2169	Transcriptional regulator
AX27061_4072	COG1272	protein, Hemolysin III
AX27061_4074	COG1278	Cold shock
AX27061_4080	COG4638	Rieske (2fe-2S)
AX27061_4083	COG0604	alcohol dehydrogenase
AX27061_4083	COG3321	synthase
AX27061_4085	COG0318	PFAM AMP-dependent synthetase and ligase
AX27061_4086	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AX27061_4091	COG0183	Belongs to the thiolase family
AX27061_4094	COG0842	Transport permease protein
AX27061_4095	COG1131	(ABC) transporter
AX27061_4098	COG2197	response regulator
AX27061_4099	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AX27061_4099	COG1116	anion transmembrane transporter activity
AX27061_4100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AX27061_4101	COG1116	anion transmembrane transporter activity
AX27061_4102	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AX27061_4103	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AX27061_4106	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AX27061_4112	COG0811	peptide transport
AX27061_4126	COG1396	sequence-specific DNA binding
AX27061_4127	COG0235	Class ii aldolase
AX27061_4129	COG3181	Tripartite tricarboxylate transporter family receptor
AX27061_4135	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AX27061_4135	COG1042	CoA-binding domain protein
AX27061_4135	COG0045	succinate-CoA ligase (ADP-forming) activity
AX27061_4136	COG1024	Enoyl-CoA hydratase
AX27061_4139	COG0583	DNA-binding transcription factor activity
AX27061_4150	COG3384	dioxygenase
AX27061_4154	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AX27061_4155	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AX27061_4156	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AX27061_4158	COG1609	Transcriptional regulator
AX27061_4159	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AX27061_4160	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AX27061_4162	COG1850	ribulose-bisphosphate carboxylase activity
AX27061_4165	COG0505	Belongs to the CarA family
AX27061_4169	COG3608	succinylglutamate desuccinylase aspartoacylase
AX27061_4169	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AX27061_4170	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AX27061_4173	COG2207	Transcriptional regulator
AX27061_4174	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AX27061_4192	COG2192	nodulation
AX27061_4194	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AX27061_4195	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_4196	COG0438	transferase activity, transferring glycosyl groups
AX27061_4198	COG5265	(ABC) transporter
AX27061_4201	COG0668	transmembrane transport
AX27061_4203	COG0166	Belongs to the GPI family
AX27061_4205	COG3685	Protein conserved in bacteria
AX27061_4209	COG0387	Pfam Sodium calcium exchanger
AX27061_4210	COG3568	Endonuclease Exonuclease Phosphatase
AX27061_4211	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AX27061_4212	COG0392	lysyltransferase activity
AX27061_4213	COG0297	glycogen (starch) synthase activity
AX27061_4214	COG0366	Alpha amylase catalytic
AX27061_4215	COG0366	Alpha amylase catalytic
AX27061_4216	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AX27061_4218	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AX27061_4219	COG1640	4-alpha-glucanotransferase
AX27061_4221	COG1113	amino acid transport
AX27061_4224	COG1546	Belongs to the CinA family
AX27061_4224	COG1058	Belongs to the CinA family
AX27061_4226	COG3852	Histidine kinase
AX27061_4231	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AX27061_4233	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AX27061_4235	COG0477	Major facilitator Superfamily
AX27061_4238	COG4771	TonB-dependent receptor
AX27061_4244	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AX27061_4251	COG1414	Transcriptional regulator
AX27061_4252	COG0179	Fumarylacetoacetate (FAA) hydrolase
AX27061_4253	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_4255	COG2721	sulfolactate sulfo-lyase activity
AX27061_4257	COG0765	amino acid transport
AX27061_4260	COG4948	Mandelate Racemase Muconate Lactonizing
AX27061_4262	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AX27061_4263	COG3958	Transketolase
AX27061_4264	COG3959	Transketolase, thiamine diphosphate binding domain
AX27061_4265	COG1802	Transcriptional regulator
AX27061_4266	COG0371	Dehydrogenase
AX27061_4267	COG3246	L-lysine catabolic process to acetate
AX27061_4268	COG1250	3-hydroxyacyl-CoA dehydrogenase
AX27061_4269	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_4271	COG0559	Belongs to the binding-protein-dependent transport system permease family
AX27061_4273	COG0410	ABC transporter
AX27061_4274	COG3321	synthase
AX27061_4274	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_4274	COG0604	alcohol dehydrogenase
AX27061_4275	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_4281	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_4284	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AX27061_4285	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AX27061_4285	COG2885	chlorophyll binding
AX27061_4289	COG2814	Major facilitator Superfamily
AX27061_4292	COG3384	dioxygenase
AX27061_4295	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AX27061_4306	COG4964	Belongs to the GSP D family
AX27061_4316	COG1846	Transcriptional regulator
AX27061_4317	COG4172	Belongs to the ABC transporter superfamily
AX27061_4318	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AX27061_4319	COG0601	transmembrane transport
AX27061_4322	COG0598	Magnesium transport protein CorA
AX27061_4326	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AX27061_4329	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AX27061_4330	COG1045	serine acetyltransferase
AX27061_4331	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AX27061_4332	COG0166	Belongs to the GPI family
AX27061_4333	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AX27061_4334	COG0489	protein tyrosine kinase activity
AX27061_4334	COG3206	protein involved in exopolysaccharide biosynthesis
AX27061_4337	COG1051	belongs to the nudix hydrolase family
AX27061_4341	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AX27061_4346	COG0463	Glycosyl transferase, family 2
AX27061_4347	COG0110	maltose O-acetyltransferase activity
AX27061_4348	COG0297	glycogen (starch) synthase activity
AX27061_4349	COG2197	response regulator
AX27061_4350	COG2197	response regulator
AX27061_4352	COG1309	transcriptional regulator
AX27061_4353	COG1960	acyl-CoA dehydrogenase activity
AX27061_4355	COG1250	3-hydroxyacyl-CoA dehydrogenase
AX27061_4355	COG1024	Enoyl-CoA hydratase
AX27061_4357	COG1024	Enoyl-CoA hydratase
AX27061_4357	COG1250	3-hydroxyacyl-CoA dehydrogenase
AX27061_4358	COG0183	Belongs to the thiolase family
AX27061_4361	COG0318	PFAM AMP-dependent synthetase and ligase
AX27061_4364	COG3181	Tripartite tricarboxylate transporter family receptor
AX27061_4366	COG1132	(ABC) transporter
AX27061_4369	COG3395	kinase activity
AX27061_4370	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AX27061_4372	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AX27061_4373	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AX27061_4376	COG1414	Transcriptional regulator
AX27061_4378	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AX27061_4382	COG0583	DNA-binding transcription factor activity
AX27061_4384	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AX27061_4385	COG1309	transcriptional regulator
AX27061_4387	COG1051	belongs to the nudix hydrolase family
AX27061_4388	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AX27061_4390	COG0784	Response regulator, receiver
AX27061_4390	COG2205	protein histidine kinase activity
AX27061_4392	COG2205	protein histidine kinase activity
AX27061_4392	COG0784	Response regulator, receiver
AX27061_4395	COG2863	cytochrome
AX27061_4396	COG3258	Cytochrome c
AX27061_4397	COG3278	Belongs to the heme-copper respiratory oxidase family
AX27061_4403	COG4695	Portal protein
AX27061_4404	COG0527	aspartate kinase activity
AX27061_4406	COG0037	tRNA processing
AX27061_4407	COG0825	malonyl-CoA metabolic process
AX27061_4409	COG0215	cysteine-tRNA ligase activity
AX27061_4412	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AX27061_4413	COG1968	undecaprenyl-diphosphatase activity
AX27061_4414	COG1253	flavin adenine dinucleotide binding
AX27061_4417	COG4263	nitrous-oxide reductase activity
AX27061_4420	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AX27061_4422	COG1477	protein flavinylation
AX27061_4423	COG4804	nuclease activity
AX27061_4428	COG0668	transmembrane transport
AX27061_4436	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AX27061_4437	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AX27061_4438	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AX27061_4445	COG3360	Dodecin
AX27061_4447	COG0583	DNA-binding transcription factor activity
AX27061_4448	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_4460	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AX27061_4461	COG2850	peptidyl-arginine hydroxylation
AX27061_4463	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AX27061_4464	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AX27061_4465	COG1994	Peptidase M50
AX27061_4466	COG0009	L-threonylcarbamoyladenylate synthase
AX27061_4467	COG2321	neutral zinc metallopeptidase
AX27061_4479	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AX27061_4480	COG3969	phosphoadenosine phosphosulfate
AX27061_4482	COG0642	Histidine kinase
AX27061_4483	COG0745	RESPONSE REGULATOR receiver
AX27061_4486	COG3188	usher protein
AX27061_4487	COG3121	Chaperone
AX27061_4490	COG3300	MHYT domain
AX27061_4490	COG5001	Diguanylate cyclase
AX27061_4492	COG2197	response regulator
AX27061_4498	COG3121	Chaperone
AX27061_4508	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_4509	COG3387	PFAM Glycoside hydrolase 15-related
AX27061_4512	COG0840	transmembrane signaling receptor activity
AX27061_4513	COG3181	Tripartite tricarboxylate transporter family receptor
AX27061_4514	COG1280	lysine exporter protein (LysE YggA)
AX27061_4519	COG3728	DNA packaging
AX27061_4524	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AX27061_4526	COG1917	Cupin 2, conserved barrel domain protein
AX27061_4526	COG2207	Transcriptional regulator
AX27061_4528	COG2084	Dehydrogenase
AX27061_4533	COG1595	DNA-templated transcription, initiation
AX27061_4536	COG1802	Transcriptional regulator
AX27061_4539	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AX27061_4544	COG0745	RESPONSE REGULATOR receiver
AX27061_4545	COG2205	protein histidine kinase activity
AX27061_4546	COG1764	response to oxidative stress
AX27061_4547	COG0583	DNA-binding transcription factor activity
AX27061_4548	COG0601	transmembrane transport
AX27061_4549	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AX27061_4550	COG0444	Belongs to the ABC transporter superfamily
AX27061_4551	COG4608	Belongs to the ABC transporter superfamily
AX27061_4554	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AX27061_4555	COG0586	Pfam SNARE associated Golgi protein
AX27061_4556	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AX27061_4557	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AX27061_4567	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AX27061_4568	COG0765	amino acid transport
AX27061_4570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AX27061_4572	COG1012	belongs to the aldehyde dehydrogenase family
AX27061_4577	COG3181	Tripartite tricarboxylate transporter family receptor
AX27061_4581	COG0348	domain, Protein
AX27061_4588	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AX27061_4589	COG0156	8-amino-7-oxononanoate synthase activity
AX27061_4591	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AX27061_4591	COG4106	trans-aconitate 2-methyltransferase activity
AX27061_4592	COG4106	trans-aconitate 2-methyltransferase activity
AX27061_4592	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AX27061_4595	COG2224	Isocitrate lyase
AX27061_4596	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AX27061_4596	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AX27061_4597	COG1858	cytochrome C peroxidase
AX27061_4598	COG0583	DNA-binding transcription factor activity
AX27061_4599	COG0473	3-isopropylmalate dehydrogenase activity
AX27061_4601	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AX27061_4602	COG0322	excinuclease ABC activity
AX27061_4603	COG1472	Belongs to the glycosyl hydrolase 3 family
AX27061_4604	COG0736	holo-[acyl-carrier-protein] synthase activity
AX27061_4605	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AX27061_4606	COG1538	Outer membrane efflux protein
AX27061_4607	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AX27061_4608	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AX27061_4613	COG3842	ATPase activity
AX27061_4614	COG4149	molybdate abc transporter
AX27061_4615	COG0725	ABC transporter, periplasmic molybdate-binding protein
AX27061_4616	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AX27061_4621	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AX27061_4623	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AX27061_4625	COG4120	Belongs to the binding-protein-dependent transport system permease family
AX27061_4627	COG0667	Aldo Keto reductase
AX27061_4629	COG0318	PFAM AMP-dependent synthetase and ligase
AX27061_4630	COG1024	Enoyl-CoA hydratase
AX27061_4632	COG1802	Transcriptional regulator
AX27061_4634	COG0183	Belongs to the thiolase family
AX27061_4635	COG1960	acyl-CoA dehydrogenase activity
AX27061_4636	COG1960	acyl-CoA dehydrogenase activity
AX27061_4637	COG0583	DNA-binding transcription factor activity
AX27061_4642	COG4213	ABC transporter substrate-binding protein
AX27061_4643	COG1129	ABC transporter
AX27061_4644	COG4214	carbohydrate transport
AX27061_4645	COG2706	6-phosphogluconolactonase activity
AX27061_4646	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AX27061_4649	COG4175	Glycine betaine
AX27061_4649	COG3448	diguanylate cyclase activity
AX27061_4650	COG4176	ABC-type proline glycine betaine transport system permease component
AX27061_4653	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AX27061_4654	COG2814	Major facilitator Superfamily
AX27061_4655	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AX27061_4656	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AX27061_4663	COG1686	Belongs to the peptidase S11 family
AX27061_4665	COG1846	Transcriptional regulator
AX27061_4666	COG2814	Major facilitator Superfamily
AX27061_4667	COG0495	leucyl-tRNA aminoacylation
AX27061_4670	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AX27061_4674	COG0154	amidase activity
AX27061_4676	COG0477	Major facilitator Superfamily
AX27061_4678	COG1250	3-hydroxyacyl-CoA dehydrogenase
AX27061_4681	COG0583	DNA-binding transcription factor activity
AX27061_4684	COG0583	DNA-binding transcription factor activity
AX27061_4685	COG0427	acetyl-CoA hydrolase
AX27061_4686	COG0583	DNA-binding transcription factor activity
AX27061_4687	COG3264	Mechanosensitive ion channel
AX27061_4687	COG1511	domain protein
AX27061_4697	COG3842	ATPase activity
AX27061_4698	COG1176	ABC-type spermidine putrescine transport system, permease component I
AX27061_4699	COG1177	transmembrane transport
AX27061_4700	COG3938	Belongs to the proline racemase family
AX27061_4703	COG0517	IMP dehydrogenase activity
AX27061_4708	COG0500	methyltransferase
AX27061_4711	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AX27061_4715	COG0667	Aldo Keto reductase
AX27061_4716	COG2207	Transcriptional regulator
AX27061_4717	COG0583	DNA-binding transcription factor activity
AX27061_4718	COG1335	isochorismatase
AX27061_4720	COG2841	Protein conserved in bacteria
AX27061_4723	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AX27061_4724	COG0438	transferase activity, transferring glycosyl groups
AX27061_4727	COG1104	cysteine desulfurase activity
AX27061_4732	COG0583	DNA-binding transcription factor activity
AX27061_4736	COG0559	Belongs to the binding-protein-dependent transport system permease family
AX27061_4738	COG0411	ABC transporter
AX27061_4740	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_4742	COG1902	pentaerythritol trinitrate reductase activity
AX27061_4746	COG1024	Enoyl-CoA hydratase
AX27061_4748	COG3181	Tripartite tricarboxylate transporter family receptor
AX27061_4750	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AX27061_4752	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AX27061_4755	COG3451	type IV secretory pathway VirB4
AX27061_4759	COG1960	acyl-CoA dehydrogenase activity
AX27061_4760	COG1024	Enoyl-CoA hydratase
AX27061_4761	COG0697	spore germination
AX27061_4762	COG1024	Enoyl-CoA hydratase
AX27061_4763	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AX27061_4764	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_4766	COG0446	pyridine nucleotide-disulphide oxidoreductase
AX27061_4766	COG1902	pentaerythritol trinitrate reductase activity
AX27061_4768	COG2814	Major facilitator Superfamily
AX27061_4770	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AX27061_4775	COG0183	Belongs to the thiolase family
AX27061_4776	COG1250	3-hydroxyacyl-CoA dehydrogenase
AX27061_4776	COG1024	Enoyl-CoA hydratase
AX27061_4777	COG1024	Enoyl-CoA hydratase
AX27061_4778	COG1960	acyl-CoA dehydrogenase activity
AX27061_4779	COG0583	DNA-binding transcription factor activity
AX27061_4781	COG2814	Major facilitator Superfamily
AX27061_4782	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AX27061_4789	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AX27061_4791	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AX27061_4792	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AX27061_4794	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AX27061_4795	COG0840	transmembrane signaling receptor activity
AX27061_4796	COG2233	PERMEase
AX27061_4798	COG1840	ABC-type Fe3 transport system, periplasmic component
AX27061_4803	COG4221	oxidoreductase activity
AX27061_4805	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AX27061_4806	COG0505	Belongs to the CarA family
AX27061_4807	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AX27061_4810	COG0745	RESPONSE REGULATOR receiver
AX27061_4813	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AX27061_4815	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AX27061_4816	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AX27061_4817	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AX27061_4819	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AX27061_4821	COG1074	ATP-dependent DNA helicase activity
AX27061_4825	COG2070	2-Nitropropane dioxygenase
AX27061_4829	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AX27061_4832	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AX27061_4833	COG0318	PFAM AMP-dependent synthetase and ligase
AX27061_4835	COG1686	Belongs to the peptidase S11 family
AX27061_4838	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AX27061_4839	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AX27061_4840	COG4974	Belongs to the 'phage' integrase family
AX27061_4841	COG0583	DNA-binding transcription factor activity
AX27061_4843	COG0028	Belongs to the TPP enzyme family
AX27061_4852	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AX27061_4859	COG0411	ABC transporter
AX27061_4861	COG0028	Belongs to the TPP enzyme family
AX27061_4862	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AX27061_4865	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AX27061_4866	COG1414	Transcriptional regulator
AX27061_4867	COG0009	L-threonylcarbamoyladenylate synthase
AX27061_4868	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AX27061_4869	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AX27061_4870	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AX27061_4872	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AX27061_4876	COG1301	dicarboxylic acid transport
AX27061_4878	COG3454	Phosphonate metabolism
AX27061_4879	COG4778	phosphonate C-P lyase system protein PhnL
AX27061_4880	COG4107	phosphonate C-P lyase system protein PhnK
AX27061_4881	COG3627	carbon phosphorus lyase activity
AX27061_4882	COG3626	phosphonate metabolism
AX27061_4883	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
AX27061_4884	COG3624	Phosphonate C-P lyase system protein PhnG
AX27061_4885	COG2188	Transcriptional regulator
AX27061_4886	COG3454	Phosphonate metabolism
AX27061_4887	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AX27061_4888	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
AX27061_4889	COG0583	DNA-binding transcription factor activity
AX27061_4890	COG0405	Gamma-glutamyltransferase
AX27061_4893	COG3639	organic phosphonate transmembrane transporter activity
AX27061_4894	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AX27061_4895	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AX27061_4897	COG0640	Transcriptional regulator
AX27061_4899	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AX27061_4901	COG0739	heme binding
AX27061_4903	COG0521	Mo-molybdopterin cofactor biosynthetic process
AX27061_4906	COG0306	phosphate transporter
AX27061_4913	COG0625	glutathione transferase activity
AX27061_4917	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AX27061_4918	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AX27061_4922	COG0126	phosphoglycerate kinase activity
AX27061_4923	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AX27061_4924	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AX27061_4927	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AX27061_4928	COG2732	(Barnase) inhibitor
AX27061_4930	COG0280	phosphate acetyltransferase
AX27061_4930	COG0281	malic enzyme
AX27061_4932	COG0436	Aminotransferase
AX27061_4936	COG0741	lytic transglycosylase activity
AX27061_4937	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AX27061_4940	COG4575	ribosome binding
AX27061_4942	COG1116	anion transmembrane transporter activity
AX27061_4943	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AX27061_4944	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AX27061_4946	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AX27061_4946	COG1648	precorrin-2 dehydrogenase activity
AX27061_4947	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AX27061_4948	COG2027	D-alanyl-D-alanine carboxypeptidase
AX27061_4951	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AX27061_4953	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AX27061_4954	COG0343	queuine tRNA-ribosyltransferase activity
AX27061_4956	COG3077	Addiction module antitoxin, RelB DinJ family
AX27061_4957	COG1862	Preprotein translocase
AX27061_4958	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AX27061_4959	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AX27061_4963	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AX27061_4966	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AX27061_4967	COG1702	phosphate starvation-inducible protein PhoH
AX27061_4968	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AX27061_4969	COG4535	Mg2 and Co2 transporter CorC
AX27061_4970	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AX27061_4971	COG0667	Aldo Keto reductase
AX27061_4974	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AX27061_4975	COG0697	spore germination
AX27061_4977	COG0678	peroxiredoxin activity
AX27061_4979	COG0412	Dienelactone hydrolase
AX27061_4981	COG0315	cyclic pyranopterin monophosphate synthase activity
AX27061_4983	COG0314	molybdopterin synthase activity
AX27061_4984	COG0521	Mo-molybdopterin cofactor biosynthetic process
AX27061_4985	COG0303	'Molybdopterin
AX27061_4987	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AX27061_4991	COG3383	formate dehydrogenase (NAD+) activity
AX27061_4992	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AX27061_4999	COG0583	DNA-binding transcription factor activity
AX27061_5000	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AX27061_5003	COG2205	protein histidine kinase activity
AX27061_5004	COG0745	RESPONSE REGULATOR receiver
AX27061_5007	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AX27061_5010	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_5014	COG2828	Protein conserved in bacteria
AX27061_5015	COG0583	DNA-binding transcription factor activity
AX27061_5016	COG0456	acetyltransferase
AX27061_5025	COG0559	Belongs to the binding-protein-dependent transport system permease family
AX27061_5027	COG0411	ABC transporter
AX27061_5028	COG0410	ABC transporter
AX27061_5030	COG4774	siderophore transport
AX27061_5034	COG4585	Histidine kinase
AX27061_5036	COG0671	phosphoesterase, PA-phosphatase related
AX27061_5037	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AX27061_5039	COG1666	GTP binding
AX27061_5040	COG1120	ATPase activity
AX27061_5041	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AX27061_5042	COG4558	Periplasmic binding protein
AX27061_5043	COG3720	iron ion transport
AX27061_5045	COG3712	iron ion homeostasis
AX27061_5046	COG1595	DNA-templated transcription, initiation
AX27061_5049	COG2378	regulation of single-species biofilm formation
AX27061_5054	COG0583	DNA-binding transcription factor activity
AX27061_5055	COG1113	amino acid transport
AX27061_5057	COG1522	sequence-specific DNA binding
AX27061_5058	COG1272	protein, Hemolysin III
AX27061_5059	COG3191	aminopeptidase activity
AX27061_5060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AX27061_5061	COG0765	amino acid transport
AX27061_5063	COG4942	peptidase
AX27061_5067	COG1999	signal sequence binding
AX27061_5071	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AX27061_5073	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AX27061_5074	COG1845	cytochrome c oxidase, subunit III
AX27061_5075	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AX27061_5077	COG4772	TonB-dependent receptor
AX27061_5082	COG0280	phosphate acetyltransferase
AX27061_5082	COG0281	malic enzyme
AX27061_5085	COG0697	spore germination
AX27061_5092	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_5094	COG0583	DNA-binding transcription factor activity
AX27061_5098	COG1396	sequence-specific DNA binding
AX27061_5099	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AX27061_5107	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AX27061_5108	COG1285	pathogenesis
AX27061_5109	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_5110	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AX27061_5113	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AX27061_5116	COG3712	iron ion homeostasis
AX27061_5117	COG1595	DNA-templated transcription, initiation
AX27061_5119	COG4221	oxidoreductase activity
AX27061_5120	COG4773	Receptor
AX27061_5124	COG5001	Diguanylate cyclase
AX27061_5125	COG0330	HflC and HflK could
AX27061_5131	COG2807	transmembrane transport
AX27061_5132	COG2207	Transcriptional regulator
AX27061_5133	COG4106	trans-aconitate 2-methyltransferase activity
AX27061_5136	COG0583	DNA-binding transcription factor activity
AX27061_5142	COG3712	iron ion homeostasis
AX27061_5147	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AX27061_5148	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AX27061_5149	COG0477	Major facilitator Superfamily
AX27061_5150	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AX27061_5151	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AX27061_5152	COG1845	cytochrome c oxidase, subunit III
AX27061_5153	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AX27061_5155	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AX27061_5156	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AX27061_5157	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AX27061_5159	COG2814	Major facilitator Superfamily
AX27061_5162	COG0625	glutathione transferase activity
AX27061_5173	COG3707	response regulator
AX27061_5174	COG2146	nitrite reductase [NAD(P)H] activity
AX27061_5174	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AX27061_5175	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AX27061_5175	COG2146	nitrite reductase [NAD(P)H] activity
AX27061_5176	COG0243	molybdopterin cofactor binding
AX27061_5178	COG0667	Aldo Keto reductase
AX27061_5181	COG0656	L-ascorbic acid biosynthetic process
AX27061_5182	COG0583	DNA-binding transcription factor activity
AX27061_5183	COG0023	Translation Initiation Factor
AX27061_5185	COG0456	acetyltransferase
AX27061_5185	COG0454	-acetyltransferase
AX27061_5186	COG0583	DNA-binding transcription factor activity
AX27061_5187	COG4948	Mandelate Racemase Muconate Lactonizing
AX27061_5190	COG0840	transmembrane signaling receptor activity
AX27061_5191	COG2199	diguanylate cyclase activity
AX27061_5191	COG2203	Gaf domain
AX27061_5192	COG0640	Transcriptional regulator
AX27061_5194	COG0740	serine-type endopeptidase activity
AX27061_5195	COG2814	Major facilitator Superfamily
AX27061_5201	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AX27061_5203	COG0596	Alpha beta hydrolase
AX27061_5205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AX27061_5207	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AX27061_5208	COG0583	DNA-binding transcription factor activity
AX27061_5215	COG0028	Belongs to the TPP enzyme family
AX27061_5219	COG1230	cation diffusion facilitator family transporter
AX27061_5223	COG1132	(ABC) transporter
AX27061_5225	COG1201	RNA secondary structure unwinding
AX27061_5227	COG1793	dna ligase
AX27061_5228	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AX27061_5228	COG1793	dna ligase
AX27061_5238	COG1960	acyl-CoA dehydrogenase activity
AX27061_5240	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AX27061_5242	COG0697	spore germination
AX27061_5244	COG3181	Tripartite tricarboxylate transporter family receptor
AX27061_5247	COG0583	DNA-binding transcription factor activity
AX27061_5248	COG0583	DNA-binding transcription factor activity
AX27061_5253	COG0583	DNA-binding transcription factor activity
AX27061_5254	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AX27061_5255	COG3181	Tripartite tricarboxylate transporter family receptor
AX27061_5256	COG4948	Mandelate Racemase Muconate Lactonizing
AX27061_5259	COG0318	PFAM AMP-dependent synthetase and ligase
AX27061_5270	COG1595	DNA-templated transcription, initiation
AX27061_5275	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AX27061_5276	COG0459	protein refolding
AX27061_5278	COG1846	Transcriptional regulator
AX27061_5282	COG1917	Cupin 2, conserved barrel domain protein
AX27061_5287	COG1137	ATPase activity
AX27061_5288	COG0410	ABC transporter
AX27061_5289	COG0246	Mannitol dehydrogenase
AX27061_5290	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AX27061_5291	COG1252	NADH dehydrogenase
AX27061_5292	COG0284	orotidine-5'-phosphate decarboxylase activity
AX27061_5293	COG1546	Belongs to the CinA family
AX27061_5296	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AX27061_5297	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AX27061_5302	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AX27061_5303	COG3639	organic phosphonate transmembrane transporter activity
AX27061_5304	COG3639	organic phosphonate transmembrane transporter activity
AX27061_5309	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AX27061_5310	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AX27061_5311	COG3135	benzoate transporter
AX27061_5314	COG2814	Major facilitator Superfamily
AX27061_5318	COG4773	Receptor
AX27061_5319	COG4804	nuclease activity
AX27061_5324	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AX27061_5325	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
AX27061_5327	COG0582	viral genome integration into host DNA
AX27061_5329	COG0012	GTP binding
AX27061_5331	COG0193	aminoacyl-tRNA hydrolase activity
AX27061_5332	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AX27061_5333	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AX27061_5334	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AX27061_5335	COG0840	transmembrane signaling receptor activity
AX27061_5336	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AX27061_5339	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AX27061_5344	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AX27061_5346	COG0204	Acyl-transferase
AX27061_5347	COG1368	sulfuric ester hydrolase activity
AX27061_5348	COG2186	Transcriptional regulator
AX27061_5349	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AX27061_5351	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AX27061_5353	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AX27061_5356	COG0745	RESPONSE REGULATOR receiver
AX27061_5357	COG0277	FAD linked oxidase domain protein
AX27061_5361	COG0166	Belongs to the GPI family
AX27061_5362	COG0405	Gamma-glutamyltransferase
AX27061_5363	COG0438	transferase activity, transferring glycosyl groups
AX27061_5364	COG0438	transferase activity, transferring glycosyl groups
AX27061_5365	COG0438	transferase activity, transferring glycosyl groups
AX27061_5370	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AX27061_5371	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AX27061_5372	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
AX27061_5374	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AX27061_5377	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AX27061_5382	COG0747	negative chemotaxis
AX27061_5383	COG0601	transmembrane transport
AX27061_5384	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AX27061_5385	COG4172	Belongs to the ABC transporter superfamily
AX27061_5386	COG0154	amidase activity
AX27061_5390	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AX27061_5390	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AX27061_5391	COG0509	glycine decarboxylation via glycine cleavage system
AX27061_5392	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AX27061_5395	COG2081	HI0933 family
AX27061_5396	COG1982	Orn Lys Arg decarboxylase major
AX27061_5400	COG3706	GGDEF domain
AX27061_5402	COG0717	Belongs to the dCTP deaminase family
AX27061_5405	COG0489	protein tyrosine kinase activity
AX27061_5408	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AX27061_5408	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AX27061_5412	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AX27061_5412	COG2755	lipolytic protein G-D-S-L family
AX27061_5414	COG0745	RESPONSE REGULATOR receiver
AX27061_5416	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AX27061_5420	COG2200	EAL domain
AX27061_5424	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AX27061_5425	COG0842	Transport permease protein
AX27061_5425	COG1129	ABC transporter
AX27061_5426	COG0842	Transport permease protein
AX27061_5428	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_5429	COG0583	DNA-binding transcription factor activity
AX27061_5430	COG0697	spore germination
AX27061_5431	COG1271	oxidase subunit
AX27061_5432	COG1294	oxidase, subunit
AX27061_5434	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AX27061_5441	COG3258	Cytochrome c
AX27061_5443	COG0625	glutathione transferase activity
AX27061_5445	COG1234	tRNA 3'-trailer cleavage
AX27061_5446	COG0477	Major facilitator Superfamily
AX27061_5447	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AX27061_5450	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AX27061_5455	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AX27061_5459	COG1595	DNA-templated transcription, initiation
AX27061_5460	COG3712	iron ion homeostasis
AX27061_5462	COG0165	Argininosuccinate lyase
AX27061_5464	COG2205	protein histidine kinase activity
AX27061_5466	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AX27061_5472	COG0477	Major facilitator Superfamily
AX27061_5474	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_5475	COG3246	L-lysine catabolic process to acetate
AX27061_5478	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AX27061_5479	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AX27061_5480	COG0154	amidase activity
AX27061_5481	COG0372	Belongs to the citrate synthase family
AX27061_5482	COG4948	Mandelate Racemase Muconate Lactonizing
AX27061_5490	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AX27061_5491	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AX27061_5492	COG0583	DNA-binding transcription factor activity
AX27061_5493	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AX27061_5498	COG1652	LysM domain
AX27061_5499	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AX27061_5500	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AX27061_5503	COG0625	glutathione transferase activity
AX27061_5509	COG1012	belongs to the aldehyde dehydrogenase family
AX27061_5517	COG3550	peptidyl-serine autophosphorylation
AX27061_5521	COG1414	Transcriptional regulator
AX27061_5523	COG0800	Aldolase
AX27061_5524	COG4948	Mandelate Racemase Muconate Lactonizing
AX27061_5525	COG2271	Major facilitator Superfamily
AX27061_5526	COG1131	(ABC) transporter
AX27061_5529	COG4774	siderophore transport
AX27061_5530	COG2814	Major facilitator Superfamily
AX27061_5531	COG0326	Molecular chaperone. Has ATPase activity
AX27061_5533	COG2233	PERMEase
AX27061_5535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AX27061_5536	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AX27061_5538	COG3246	L-lysine catabolic process to acetate
AX27061_5540	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_5565	COG5002	protein histidine kinase activity
AX27061_5565	COG0784	Response regulator, receiver
AX27061_5565	COG2198	Histidine kinase
AX27061_5569	COG0583	DNA-binding transcription factor activity
AX27061_5571	COG1695	Transcriptional regulator
AX27061_5574	COG0477	Major facilitator Superfamily
AX27061_5577	COG0277	FAD linked oxidase domain protein
AX27061_5579	COG3842	ATPase activity
AX27061_5580	COG1176	ABC-type spermidine putrescine transport system, permease component I
AX27061_5584	COG0628	permease
AX27061_5585	COG0583	DNA-binding transcription factor activity
AX27061_5586	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AX27061_5590	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
AX27061_5592	COG2186	Transcriptional regulator
AX27061_5594	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AX27061_5596	COG0559	Belongs to the binding-protein-dependent transport system permease family
AX27061_5598	COG0411	ABC transporter
AX27061_5599	COG0410	ABC transporter
AX27061_5600	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_5601	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AX27061_5603	COG0508	dehydrogenase complex catalyzes the overall conversion of
AX27061_5604	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AX27061_5605	COG0583	DNA-binding transcription factor activity
AX27061_5606	COG0129	dihydroxy-acid dehydratase activity
AX27061_5608	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AX27061_5612	COG2200	EAL domain
AX27061_5613	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AX27061_5614	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AX27061_5615	COG1250	3-hydroxyacyl-CoA dehydrogenase
AX27061_5616	COG2031	fatty acid transporter
AX27061_5617	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_5618	COG1414	Transcriptional regulator
AX27061_5621	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AX27061_5624	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AX27061_5628	COG0288	reversible hydration of carbon dioxide
AX27061_5629	COG1802	Transcriptional regulator
AX27061_5630	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_5632	COG0559	Belongs to the binding-protein-dependent transport system permease family
AX27061_5636	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_5639	COG0625	glutathione transferase activity
AX27061_5642	COG0583	DNA-binding transcription factor activity
AX27061_5644	COG0583	DNA-binding transcription factor activity
AX27061_5645	COG0477	Major facilitator Superfamily
AX27061_5650	COG0318	PFAM AMP-dependent synthetase and ligase
AX27061_5654	COG1464	Belongs to the NlpA lipoprotein family
AX27061_5657	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AX27061_5658	COG2890	protein-(glutamine-N5) methyltransferase activity
AX27061_5659	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AX27061_5660	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AX27061_5661	COG1280	lysine exporter protein (LysE YggA)
AX27061_5662	COG1522	sequence-specific DNA binding
AX27061_5666	COG3622	Belongs to the hyi family
AX27061_5669	COG0477	Major facilitator Superfamily
AX27061_5671	COG2186	Transcriptional regulator
AX27061_5672	COG3395	kinase activity
AX27061_5673	COG2084	Dehydrogenase
AX27061_5674	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AX27061_5675	COG3622	Belongs to the hyi family
AX27061_5676	COG0235	Class ii aldolase
AX27061_5686	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AX27061_5689	COG0142	geranyltranstransferase activity
AX27061_5690	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AX27061_5691	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AX27061_5692	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AX27061_5693	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AX27061_5696	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AX27061_5698	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AX27061_5700	COG2186	Transcriptional regulator
AX27061_5701	COG5002	protein histidine kinase activity
AX27061_5701	COG3447	MASE1 domain protein
AX27061_5701	COG5001	Diguanylate cyclase
AX27061_5702	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AX27061_5703	COG0793	Belongs to the peptidase S41A family
AX27061_5704	COG4942	peptidase
AX27061_5705	COG0588	phosphoglycerate mutase activity
AX27061_5707	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AX27061_5708	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AX27061_5709	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AX27061_5710	COG3181	Tripartite tricarboxylate transporter family receptor
AX27061_5712	COG1040	competence protein
AX27061_5713	COG2226	methyltransferase
AX27061_5714	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AX27061_5715	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AX27061_5716	COG0569	domain protein
AX27061_5717	COG2204	response regulator
AX27061_5718	COG5000	phosphorelay sensor kinase activity
AX27061_5720	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AX27061_5720	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AX27061_5721	COG1280	lysine exporter protein (LysE YggA)
AX27061_5723	COG2076	Multidrug Resistance protein
AX27061_5724	COG1733	regulation of RNA biosynthetic process
AX27061_5728	COG0546	phosphoglycolate phosphatase activity
AX27061_5730	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AX27061_5731	COG0242	peptide deformylase activity
AX27061_5732	COG0758	DNA mediated transformation
AX27061_5735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AX27061_5736	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AX27061_5737	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AX27061_5738	COG3181	Tripartite tricarboxylate transporter family receptor
AX27061_5742	COG1238	metal cluster binding
AX27061_5743	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AX27061_5744	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AX27061_5747	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AX27061_5748	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AX27061_5749	COG4988	ABC transporter
AX27061_5751	COG1294	oxidase, subunit
AX27061_5754	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AX27061_5756	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AX27061_5759	COG1137	ATPase activity
AX27061_5760	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AX27061_5762	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AX27061_5763	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AX27061_5768	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AX27061_5770	COG0792	nuclease activity
AX27061_5771	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AX27061_5773	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AX27061_5775	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AX27061_5777	COG1309	transcriptional regulator
AX27061_5778	COG0471	metal ion transport
AX27061_5779	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
AX27061_5780	COG0772	Belongs to the SEDS family
AX27061_5781	COG0768	penicillin binding
AX27061_5783	COG1792	Involved in formation and maintenance of cell shape
AX27061_5784	COG1077	Cell shape determining protein MreB Mrl
AX27061_5785	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AX27061_5786	COG0154	amidase activity
AX27061_5787	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AX27061_5789	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AX27061_5790	COG0708	Exodeoxyribonuclease III
AX27061_5791	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AX27061_5793	COG0583	DNA-binding transcription factor activity
AX27061_5795	COG0583	DNA-binding transcription factor activity
AX27061_5798	COG0411	ABC transporter
AX27061_5801	COG1764	response to oxidative stress
AX27061_5802	COG1846	Transcriptional regulator
AX27061_5815	COG0640	Transcriptional regulator
AX27061_5820	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AX27061_5821	COG3189	MarR family transcriptional regulator
AX27061_5825	COG1028	Short-chain dehydrogenase reductase Sdr
AX27061_5826	COG0352	thiamine-phosphate diphosphorylase activity
AX27061_5826	COG0351	phosphomethylpyrimidine kinase
AX27061_5826	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AX27061_5828	COG0443	Heat shock 70 kDa protein
AX27061_5833	COG3210	domain, Protein
AX27061_5835	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AX27061_5836	COG0513	Belongs to the DEAD box helicase family
AX27061_5838	COG0617	tRNA 3'-terminal CCA addition
AX27061_5840	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AX27061_5841	COG2308	Evidence 4 Homologs of previously reported genes of
AX27061_5843	COG1305	Transglutaminase-like
AX27061_5847	COG1950	PFAM Membrane protein of
AX27061_5848	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AX27061_5849	COG0438	transferase activity, transferring glycosyl groups
AX27061_5852	COG0066	3-isopropylmalate dehydratase activity
AX27061_5855	COG0583	DNA-binding transcription factor activity
AX27061_5857	COG0477	Major facilitator Superfamily
AX27061_5858	COG0154	amidase activity
AX27061_5859	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AX27061_5862	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AX27061_5864	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AX27061_5865	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
AX27061_5867	COG0803	Belongs to the bacterial solute-binding protein 9 family
AX27061_5871	COG0735	belongs to the Fur family
AX27061_5872	COG0523	cobalamin synthesis protein
AX27061_5873	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AX27061_5875	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AX27061_5876	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AX27061_5878	COG2096	Adenosyltransferase
AX27061_5879	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AX27061_5882	COG0321	lipoyl(octanoyl) transferase activity
AX27061_5883	COG2921	Belongs to the UPF0250 family
AX27061_5885	COG1686	Belongs to the peptidase S11 family
AX27061_5890	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AX27061_5892	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AX27061_5895	COG0859	PFAM glycosyl transferase family 9
AX27061_5900	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AX27061_5911	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AX27061_5913	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AX27061_5916	COG0175	sulfate reduction
AX27061_5923	COG0367	asparagine synthase
AX27061_5926	COG2814	Major facilitator Superfamily
AX27061_5927	COG0697	spore germination
AX27061_5932	COG3568	Endonuclease Exonuclease Phosphatase
AX27061_5933	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AX27061_5938	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AX27061_5941	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AX27061_5942	COG1956	GAF domain-containing protein
AX27061_5943	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AX27061_5945	COG1422	Protein of unknown function (DUF1090)
AX27061_5948	COG2186	Transcriptional regulator
AX27061_5949	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AX27061_5957	COG4106	trans-aconitate 2-methyltransferase activity
AX27061_5958	COG0629	single-stranded DNA binding
AX27061_5959	COG2814	Major facilitator Superfamily
AX27061_5961	COG0625	glutathione transferase activity
AX27061_5962	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AX27061_5963	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AX27061_5964	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AX27061_5966	COG1965	Belongs to the frataxin family
AX27061_5967	COG0019	diaminopimelate decarboxylase activity
AX27061_5969	COG1333	cytochrome c biogenesis protein
AX27061_5971	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AX27061_5974	COG4232	protein-disulfide reductase activity
AX27061_5975	COG1324	tolerance protein
AX27061_5977	COG0203	ribosomal protein L17
AX27061_5978	COG0202	RNA polymerase activity
AX27061_5979	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AX27061_5980	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AX27061_5981	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AX27061_5982	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AX27061_5983	COG0201	protein transport
AX27061_5984	COG0200	Binds to the 23S rRNA
AX27061_5985	COG1841	ribosomal large subunit assembly
AX27061_5986	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AX27061_5987	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AX27061_5988	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AX27061_5989	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AX27061_5990	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AX27061_5991	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AX27061_5992	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AX27061_5993	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AX27061_5996	COG2169	Transcriptional regulator
AX27061_5996	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AX27061_5999	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AX27061_6001	COG0411	ABC transporter
AX27061_6002	COG0410	ABC transporter
AX27061_6003	COG4177	L-phenylalanine transmembrane transporter activity
AX27061_6006	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AX27061_6007	COG0255	Belongs to the universal ribosomal protein uL29 family
AX27061_6008	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AX27061_6009	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AX27061_6010	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AX27061_6011	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AX27061_6012	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AX27061_6013	COG0089	rRNA binding
AX27061_6014	COG0088	Forms part of the polypeptide exit tunnel
AX27061_6015	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AX27061_6016	COG0051	transcription antitermination factor activity, RNA binding
AX27061_6017	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AX27061_6018	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AX27061_6019	COG0049	tRNA binding
AX27061_6021	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AX27061_6022	COG0745	RESPONSE REGULATOR receiver
AX27061_6025	COG5002	protein histidine kinase activity
AX27061_6028	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AX27061_6029	COG0085	RNA polymerase activity
AX27061_6030	COG0222	ribosome binding
AX27061_6031	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AX27061_6032	COG0081	regulation of translation
AX27061_6033	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AX27061_6035	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AX27061_6036	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AX27061_6041	COG1840	ABC-type Fe3 transport system, periplasmic component
AX27061_6042	COG3842	ATPase activity
AX27061_6044	COG1349	DNA-binding transcription factor activity
AX27061_6049	COG0583	DNA-binding transcription factor activity
AX27061_6050	COG0252	asparaginase activity
AX27061_6051	COG1475	DNA binding
AX27061_6053	COG1192	Involved in chromosome partitioning
AX27061_6054	COG0357	Ribosomal RNA small subunit methyltransferase G
AX27061_6055	COG0445	tRNA wobble uridine modification
AX27061_6056	COG1278	Cold shock
AX27061_6057	COG3180	Ammonia monooxygenase
AX27061_6058	COG0436	Aminotransferase
AX27061_6064	COG0038	chloride channel
AX27061_6067	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AX27061_6069	COG0601	transmembrane transport
AX27061_6070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AX27061_6071	COG0444	Belongs to the ABC transporter superfamily
AX27061_6072	COG4608	Belongs to the ABC transporter superfamily
AX27061_6073	COG1473	amidohydrolase
AX27061_6076	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AX27061_6077	COG0753	catalase activity
AX27061_6080	COG0594	ribonuclease P activity
AX27061_6081	COG0230	Belongs to the bacterial ribosomal protein bL34 family