locus-tag	class	description
IUJ48_00015	COG1131	(ABC) transporter
IUJ48_00020	COG2271	Major facilitator Superfamily
IUJ48_00025	COG4948	Mandelate Racemase Muconate Lactonizing
IUJ48_00030	COG0800	Aldolase
IUJ48_00040	COG1414	Transcriptional regulator
IUJ48_00060	COG3550	peptidyl-serine autophosphorylation
IUJ48_00095	COG1012	belongs to the aldehyde dehydrogenase family
IUJ48_00130	COG0625	glutathione transferase activity
IUJ48_00145	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IUJ48_00150	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IUJ48_00155	COG1652	LysM domain
IUJ48_00175	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IUJ48_00180	COG0583	DNA-binding transcription factor activity
IUJ48_00185	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IUJ48_00190	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IUJ48_00235	COG4948	Mandelate Racemase Muconate Lactonizing
IUJ48_00240	COG0372	Belongs to the citrate synthase family
IUJ48_00245	COG0154	amidase activity
IUJ48_00250	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IUJ48_00255	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IUJ48_00270	COG3246	L-lysine catabolic process to acetate
IUJ48_00275	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_00285	COG0477	Major facilitator Superfamily
IUJ48_00315	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IUJ48_00325	COG2205	protein histidine kinase activity
IUJ48_00330	COG0165	Argininosuccinate lyase
IUJ48_00340	COG3712	iron ion homeostasis
IUJ48_00345	COG1595	DNA-templated transcription, initiation
IUJ48_00365	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IUJ48_00390	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IUJ48_00405	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IUJ48_00415	COG1234	tRNA 3'-trailer cleavage
IUJ48_00425	COG0625	glutathione transferase activity
IUJ48_00435	COG3258	Cytochrome c
IUJ48_00470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IUJ48_00480	COG1294	oxidase, subunit
IUJ48_00485	COG1271	oxidase subunit
IUJ48_00490	COG0697	spore germination
IUJ48_00495	COG0583	DNA-binding transcription factor activity
IUJ48_00500	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_00510	COG0842	Transport permease protein
IUJ48_00515	COG0842	Transport permease protein
IUJ48_00515	COG1129	ABC transporter
IUJ48_00520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IUJ48_00540	COG2200	EAL domain
IUJ48_00560	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IUJ48_00575	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IUJ48_00575	COG2755	lipolytic protein G-D-S-L family
IUJ48_00590	COG1054	Belongs to the UPF0176 family
IUJ48_00595	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IUJ48_00595	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IUJ48_00605	COG0489	protein tyrosine kinase activity
IUJ48_00620	COG0717	Belongs to the dCTP deaminase family
IUJ48_00630	COG3706	GGDEF domain
IUJ48_00650	COG2081	HI0933 family
IUJ48_00665	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IUJ48_00670	COG0509	glycine decarboxylation via glycine cleavage system
IUJ48_00675	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IUJ48_00675	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IUJ48_00715	COG0154	amidase activity
IUJ48_00720	COG4172	Belongs to the ABC transporter superfamily
IUJ48_00725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IUJ48_00730	COG0601	transmembrane transport
IUJ48_00735	COG0747	negative chemotaxis
IUJ48_00750	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IUJ48_00755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IUJ48_00785	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IUJ48_00790	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IUJ48_00815	COG0438	transferase activity, transferring glycosyl groups
IUJ48_00820	COG0438	transferase activity, transferring glycosyl groups
IUJ48_00825	COG0438	transferase activity, transferring glycosyl groups
IUJ48_00830	COG0405	Gamma-glutamyltransferase
IUJ48_00835	COG0166	Belongs to the GPI family
IUJ48_00850	COG0277	FAD linked oxidase domain protein
IUJ48_00855	COG0745	RESPONSE REGULATOR receiver
IUJ48_00870	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IUJ48_00870	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IUJ48_00880	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IUJ48_00890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IUJ48_00895	COG2186	Transcriptional regulator
IUJ48_00900	COG1368	sulfuric ester hydrolase activity
IUJ48_00905	COG0204	Acyl-transferase
IUJ48_00915	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
IUJ48_00940	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IUJ48_00955	COG0840	transmembrane signaling receptor activity
IUJ48_00960	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IUJ48_00980	COG0193	aminoacyl-tRNA hydrolase activity
IUJ48_00990	COG0012	GTP binding
IUJ48_01005	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
IUJ48_01010	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
IUJ48_01040	COG4804	nuclease activity
IUJ48_01045	COG4773	Receptor
IUJ48_01050	COG0488	(ABC) transporter
IUJ48_01065	COG2814	Major facilitator Superfamily
IUJ48_01080	COG3135	benzoate transporter
IUJ48_01085	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IUJ48_01090	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IUJ48_01095	COG0742	ribosomal rna small subunit methyltransferase
IUJ48_01115	COG3639	organic phosphonate transmembrane transporter activity
IUJ48_01120	COG3639	organic phosphonate transmembrane transporter activity
IUJ48_01125	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IUJ48_01150	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
IUJ48_01155	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IUJ48_01170	COG1546	Belongs to the CinA family
IUJ48_01175	COG0284	orotidine-5'-phosphate decarboxylase activity
IUJ48_01180	COG1252	NADH dehydrogenase
IUJ48_01185	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IUJ48_01190	COG0246	Mannitol dehydrogenase
IUJ48_01200	COG1137	ATPase activity
IUJ48_01225	COG1917	Cupin 2, conserved barrel domain protein
IUJ48_01245	COG1846	Transcriptional regulator
IUJ48_01255	COG0459	protein refolding
IUJ48_01260	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IUJ48_01290	COG1595	DNA-templated transcription, initiation
IUJ48_01335	COG0318	PFAM AMP-dependent synthetase and ligase
IUJ48_01350	COG4948	Mandelate Racemase Muconate Lactonizing
IUJ48_01355	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_01360	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IUJ48_01365	COG0583	DNA-binding transcription factor activity
IUJ48_01390	COG0583	DNA-binding transcription factor activity
IUJ48_01395	COG0583	DNA-binding transcription factor activity
IUJ48_01400	COG0436	Aminotransferase
IUJ48_01410	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_01420	COG0697	spore germination
IUJ48_01425	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IUJ48_01435	COG1960	acyl-CoA dehydrogenase activity
IUJ48_01475	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
IUJ48_01475	COG1793	dna ligase
IUJ48_01480	COG1793	dna ligase
IUJ48_01495	COG1132	(ABC) transporter
IUJ48_01515	COG1230	cation diffusion facilitator family transporter
IUJ48_01535	COG0028	Belongs to the TPP enzyme family
IUJ48_01570	COG0583	DNA-binding transcription factor activity
IUJ48_01575	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IUJ48_01585	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IUJ48_01595	COG0596	Alpha beta hydrolase
IUJ48_01605	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IUJ48_01635	COG2814	Major facilitator Superfamily
IUJ48_01640	COG0740	serine-type endopeptidase activity
IUJ48_01650	COG0640	Transcriptional regulator
IUJ48_01655	COG2203	Gaf domain
IUJ48_01655	COG2199	diguanylate cyclase activity
IUJ48_01660	COG0840	transmembrane signaling receptor activity
IUJ48_01675	COG4948	Mandelate Racemase Muconate Lactonizing
IUJ48_01680	COG0583	DNA-binding transcription factor activity
IUJ48_01685	COG0454	-acetyltransferase
IUJ48_01685	COG0456	acetyltransferase
IUJ48_01695	COG0023	Translation Initiation Factor
IUJ48_01700	COG0583	DNA-binding transcription factor activity
IUJ48_01705	COG0656	L-ascorbic acid biosynthetic process
IUJ48_01720	COG0667	Aldo Keto reductase
IUJ48_01730	COG0243	molybdopterin cofactor binding
IUJ48_01735	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IUJ48_01735	COG2146	nitrite reductase [NAD(P)H] activity
IUJ48_01740	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IUJ48_01740	COG2146	nitrite reductase [NAD(P)H] activity
IUJ48_01745	COG3707	response regulator
IUJ48_01800	COG0625	glutathione transferase activity
IUJ48_01815	COG2814	Major facilitator Superfamily
IUJ48_01825	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IUJ48_01830	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IUJ48_01835	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IUJ48_01845	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IUJ48_01850	COG1845	cytochrome c oxidase, subunit III
IUJ48_01855	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IUJ48_01860	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IUJ48_01865	COG0477	Major facilitator Superfamily
IUJ48_01870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ48_01875	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IUJ48_01900	COG3712	iron ion homeostasis
IUJ48_01930	COG0583	DNA-binding transcription factor activity
IUJ48_01945	COG4106	trans-aconitate 2-methyltransferase activity
IUJ48_01950	COG2207	Transcriptional regulator
IUJ48_01955	COG2807	transmembrane transport
IUJ48_01980	COG0330	HflC and HflK could
IUJ48_01985	COG5001	Diguanylate cyclase
IUJ48_02005	COG4773	Receptor
IUJ48_02010	COG4221	oxidoreductase activity
IUJ48_02020	COG1595	DNA-templated transcription, initiation
IUJ48_02025	COG3712	iron ion homeostasis
IUJ48_02040	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IUJ48_02055	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IUJ48_02060	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_02065	COG1285	pathogenesis
IUJ48_02070	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
IUJ48_02110	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IUJ48_02115	COG1396	sequence-specific DNA binding
IUJ48_02135	COG0583	DNA-binding transcription factor activity
IUJ48_02145	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_02180	COG0697	spore germination
IUJ48_02195	COG0280	phosphate acetyltransferase
IUJ48_02195	COG0281	malic enzyme
IUJ48_02215	COG4772	TonB-dependent receptor
IUJ48_02225	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IUJ48_02230	COG1845	cytochrome c oxidase, subunit III
IUJ48_02235	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IUJ48_02245	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
IUJ48_02265	COG1999	signal sequence binding
IUJ48_02285	COG4942	peptidase
IUJ48_02290	COG1126	abc transporter atp-binding protein
IUJ48_02295	COG0765	amino acid transport
IUJ48_02300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ48_02305	COG3191	aminopeptidase activity
IUJ48_02310	COG1272	protein, Hemolysin III
IUJ48_02315	COG1522	sequence-specific DNA binding
IUJ48_02325	COG1113	amino acid transport
IUJ48_02330	COG0583	DNA-binding transcription factor activity
IUJ48_02355	COG2378	regulation of single-species biofilm formation
IUJ48_02370	COG1595	DNA-templated transcription, initiation
IUJ48_02375	COG3712	iron ion homeostasis
IUJ48_02385	COG3720	iron ion transport
IUJ48_02390	COG4558	Periplasmic binding protein
IUJ48_02395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IUJ48_02400	COG1120	ATPase activity
IUJ48_02405	COG1666	GTP binding
IUJ48_02420	COG0671	phosphoesterase, PA-phosphatase related
IUJ48_02425	COG4585	Histidine kinase
IUJ48_02445	COG4774	siderophore transport
IUJ48_02470	COG0559	Belongs to the binding-protein-dependent transport system permease family
IUJ48_02510	COG0456	acetyltransferase
IUJ48_02515	COG0583	DNA-binding transcription factor activity
IUJ48_02520	COG2828	Protein conserved in bacteria
IUJ48_02540	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_02555	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IUJ48_02590	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IUJ48_02595	COG0583	DNA-binding transcription factor activity
IUJ48_02620	COG2223	nitrite transmembrane transporter activity
IUJ48_02630	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IUJ48_02635	COG3383	formate dehydrogenase (NAD+) activity
IUJ48_02655	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IUJ48_02665	COG0303	'Molybdopterin
IUJ48_02670	COG0521	Mo-molybdopterin cofactor biosynthetic process
IUJ48_02675	COG0314	molybdopterin synthase activity
IUJ48_02685	COG0315	cyclic pyranopterin monophosphate synthase activity
IUJ48_02695	COG0412	Dienelactone hydrolase
IUJ48_02705	COG0678	peroxiredoxin activity
IUJ48_02715	COG0697	spore germination
IUJ48_02760	COG0667	Aldo Keto reductase
IUJ48_02765	COG0815	Transfers the fatty acyl group on membrane lipoproteins
IUJ48_02770	COG4535	Mg2 and Co2 transporter CorC
IUJ48_02775	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IUJ48_02780	COG1702	phosphate starvation-inducible protein PhoH
IUJ48_02785	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IUJ48_02795	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IUJ48_02815	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IUJ48_02820	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IUJ48_02825	COG1862	Preprotein translocase
IUJ48_02830	COG3077	Addiction module antitoxin, RelB DinJ family
IUJ48_02840	COG0343	queuine tRNA-ribosyltransferase activity
IUJ48_02845	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IUJ48_02855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IUJ48_02870	COG2027	D-alanyl-D-alanine carboxypeptidase
IUJ48_02875	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IUJ48_02880	COG1648	precorrin-2 dehydrogenase activity
IUJ48_02880	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IUJ48_02885	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IUJ48_02890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IUJ48_02895	COG1116	anion transmembrane transporter activity
IUJ48_02905	COG4575	ribosome binding
IUJ48_02920	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IUJ48_02925	COG0741	lytic transglycosylase activity
IUJ48_02940	COG0436	Aminotransferase
IUJ48_02950	COG0281	malic enzyme
IUJ48_02950	COG0280	phosphate acetyltransferase
IUJ48_02960	COG2732	(Barnase) inhibitor
IUJ48_02965	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IUJ48_02975	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IUJ48_02980	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IUJ48_02985	COG0126	phosphoglycerate kinase activity
IUJ48_03000	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IUJ48_03005	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IUJ48_03025	COG0625	glutathione transferase activity
IUJ48_03060	COG0306	phosphate transporter
IUJ48_03070	COG0521	Mo-molybdopterin cofactor biosynthetic process
IUJ48_03080	COG0739	heme binding
IUJ48_03090	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IUJ48_03100	COG0640	Transcriptional regulator
IUJ48_03110	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IUJ48_03115	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
IUJ48_03120	COG3639	organic phosphonate transmembrane transporter activity
IUJ48_03135	COG0405	Gamma-glutamyltransferase
IUJ48_03140	COG0583	DNA-binding transcription factor activity
IUJ48_03145	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
IUJ48_03150	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
IUJ48_03155	COG3454	Phosphonate metabolism
IUJ48_03160	COG2188	Transcriptional regulator
IUJ48_03165	COG3624	Phosphonate C-P lyase system protein PhnG
IUJ48_03170	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
IUJ48_03175	COG3626	phosphonate metabolism
IUJ48_03180	COG3627	carbon phosphorus lyase activity
IUJ48_03185	COG4107	phosphonate C-P lyase system protein PhnK
IUJ48_03190	COG4778	phosphonate C-P lyase system protein PhnL
IUJ48_03195	COG3454	Phosphonate metabolism
IUJ48_03205	COG1301	dicarboxylic acid transport
IUJ48_03225	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
IUJ48_03235	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
IUJ48_03240	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IUJ48_03245	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IUJ48_03250	COG0009	L-threonylcarbamoyladenylate synthase
IUJ48_03255	COG1414	Transcriptional regulator
IUJ48_03260	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IUJ48_03275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ48_03280	COG0028	Belongs to the TPP enzyme family
IUJ48_03325	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IUJ48_03370	COG0028	Belongs to the TPP enzyme family
IUJ48_03375	COG0583	DNA-binding transcription factor activity
IUJ48_03380	COG4974	Belongs to the 'phage' integrase family
IUJ48_03385	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IUJ48_03390	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IUJ48_03405	COG1686	Belongs to the peptidase S11 family
IUJ48_03420	COG0318	PFAM AMP-dependent synthetase and ligase
IUJ48_03425	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IUJ48_03440	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IUJ48_03460	COG2070	2-Nitropropane dioxygenase
IUJ48_03480	COG1074	ATP-dependent DNA helicase activity
IUJ48_03490	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IUJ48_03505	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IUJ48_03510	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IUJ48_03520	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IUJ48_03535	COG0745	RESPONSE REGULATOR receiver
IUJ48_03555	COG0505	Belongs to the CarA family
IUJ48_03560	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IUJ48_03570	COG4221	oxidoreductase activity
IUJ48_03585	COG3842	ATPase activity
IUJ48_03605	COG2233	PERMEase
IUJ48_03610	COG0840	transmembrane signaling receptor activity
IUJ48_03615	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IUJ48_03620	COG1534	Rna-binding protein
IUJ48_03625	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
IUJ48_03630	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IUJ48_03640	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IUJ48_03650	COG0248	Ppx GppA phosphatase
IUJ48_03675	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IUJ48_03680	COG2814	Major facilitator Superfamily
IUJ48_03695	COG0583	DNA-binding transcription factor activity
IUJ48_03700	COG1960	acyl-CoA dehydrogenase activity
IUJ48_03710	COG0183	Belongs to the thiolase family
IUJ48_03730	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IUJ48_03735	COG1846	Transcriptional regulator
IUJ48_03745	COG0604	alcohol dehydrogenase
IUJ48_03745	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_03745	COG3321	synthase
IUJ48_03750	COG2814	Major facilitator Superfamily
IUJ48_03755	COG1902	pentaerythritol trinitrate reductase activity
IUJ48_03755	COG0446	pyridine nucleotide-disulphide oxidoreductase
IUJ48_03765	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_03770	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IUJ48_03775	COG1024	Enoyl-CoA hydratase
IUJ48_03780	COG0697	spore germination
IUJ48_03785	COG1024	Enoyl-CoA hydratase
IUJ48_03790	COG1960	acyl-CoA dehydrogenase activity
IUJ48_03830	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IUJ48_03840	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IUJ48_03850	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_03860	COG1024	Enoyl-CoA hydratase
IUJ48_03865	COG1024	Enoyl-CoA hydratase
IUJ48_03880	COG1902	pentaerythritol trinitrate reductase activity
IUJ48_03890	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_03910	COG0559	Belongs to the binding-protein-dependent transport system permease family
IUJ48_03930	COG0583	DNA-binding transcription factor activity
IUJ48_03945	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IUJ48_03960	COG1024	Enoyl-CoA hydratase
IUJ48_03965	COG1104	cysteine desulfurase activity
IUJ48_03970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IUJ48_03990	COG0438	transferase activity, transferring glycosyl groups
IUJ48_03995	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IUJ48_04010	COG2841	Protein conserved in bacteria
IUJ48_04020	COG1335	isochorismatase
IUJ48_04025	COG0583	DNA-binding transcription factor activity
IUJ48_04030	COG2207	Transcriptional regulator
IUJ48_04035	COG0667	Aldo Keto reductase
IUJ48_04050	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
IUJ48_04065	COG0500	methyltransferase
IUJ48_04095	COG0517	IMP dehydrogenase activity
IUJ48_04110	COG3938	Belongs to the proline racemase family
IUJ48_04115	COG1177	transmembrane transport
IUJ48_04120	COG1176	ABC-type spermidine putrescine transport system, permease component I
IUJ48_04125	COG3842	ATPase activity
IUJ48_04175	COG1511	domain protein
IUJ48_04175	COG3264	Mechanosensitive ion channel
IUJ48_04180	COG0583	DNA-binding transcription factor activity
IUJ48_04185	COG0427	acetyl-CoA hydrolase
IUJ48_04190	COG0583	DNA-binding transcription factor activity
IUJ48_04240	COG0583	DNA-binding transcription factor activity
IUJ48_04255	COG1250	3-hydroxyacyl-CoA dehydrogenase
IUJ48_04265	COG0477	Major facilitator Superfamily
IUJ48_04275	COG0154	amidase activity
IUJ48_04295	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IUJ48_04310	COG0495	leucyl-tRNA aminoacylation
IUJ48_04315	COG2814	Major facilitator Superfamily
IUJ48_04320	COG1846	Transcriptional regulator
IUJ48_04335	COG1686	Belongs to the peptidase S11 family
IUJ48_04370	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IUJ48_04375	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IUJ48_04380	COG2814	Major facilitator Superfamily
IUJ48_04385	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IUJ48_04395	COG4176	ABC-type proline glycine betaine transport system permease component
IUJ48_04415	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IUJ48_04420	COG2706	6-phosphogluconolactonase activity
IUJ48_04425	COG4214	carbohydrate transport
IUJ48_04430	COG1129	ABC transporter
IUJ48_04435	COG4213	ABC transporter substrate-binding protein
IUJ48_04460	COG0583	DNA-binding transcription factor activity
IUJ48_04465	COG1960	acyl-CoA dehydrogenase activity
IUJ48_04470	COG1960	acyl-CoA dehydrogenase activity
IUJ48_04475	COG0183	Belongs to the thiolase family
IUJ48_04485	COG1802	Transcriptional regulator
IUJ48_04495	COG1024	Enoyl-CoA hydratase
IUJ48_04500	COG0318	PFAM AMP-dependent synthetase and ligase
IUJ48_04510	COG0667	Aldo Keto reductase
IUJ48_04520	COG4120	Belongs to the binding-protein-dependent transport system permease family
IUJ48_04530	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IUJ48_04540	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IUJ48_04565	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
IUJ48_04570	COG0725	ABC transporter, periplasmic molybdate-binding protein
IUJ48_04575	COG4149	molybdate abc transporter
IUJ48_04580	COG3842	ATPase activity
IUJ48_04605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IUJ48_04610	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IUJ48_04620	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IUJ48_04625	COG0736	holo-[acyl-carrier-protein] synthase activity
IUJ48_04640	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IUJ48_04650	COG0473	3-isopropylmalate dehydrogenase activity
IUJ48_04655	COG0583	DNA-binding transcription factor activity
IUJ48_04660	COG1858	cytochrome C peroxidase
IUJ48_04665	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IUJ48_04665	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IUJ48_04670	COG2224	Isocitrate lyase
IUJ48_04695	COG0156	8-amino-7-oxononanoate synthase activity
IUJ48_04700	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IUJ48_04715	COG3278	Belongs to the heme-copper respiratory oxidase family
IUJ48_04735	COG0348	domain, Protein
IUJ48_04780	COG1012	belongs to the aldehyde dehydrogenase family
IUJ48_04790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ48_04800	COG0765	amino acid transport
IUJ48_04805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IUJ48_04865	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IUJ48_04870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IUJ48_04875	COG0586	Pfam SNARE associated Golgi protein
IUJ48_04880	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IUJ48_04895	COG4608	Belongs to the ABC transporter superfamily
IUJ48_04900	COG0444	Belongs to the ABC transporter superfamily
IUJ48_04905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IUJ48_04910	COG0601	transmembrane transport
IUJ48_04915	COG0583	DNA-binding transcription factor activity
IUJ48_04920	COG1764	response to oxidative stress
IUJ48_04925	COG2205	protein histidine kinase activity
IUJ48_04955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IUJ48_04970	COG1802	Transcriptional regulator
IUJ48_04985	COG1595	DNA-templated transcription, initiation
IUJ48_05005	COG2084	Dehydrogenase
IUJ48_05025	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IUJ48_05035	COG0582	viral genome integration into host DNA
IUJ48_05080	COG3728	DNA packaging
IUJ48_05105	COG1280	lysine exporter protein (LysE YggA)
IUJ48_05110	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_05115	COG0840	transmembrane signaling receptor activity
IUJ48_05130	COG3387	PFAM Glycoside hydrolase 15-related
IUJ48_05175	COG3188	usher protein
IUJ48_05180	COG3121	Chaperone
IUJ48_05210	COG2197	response regulator
IUJ48_05220	COG5001	Diguanylate cyclase
IUJ48_05220	COG3300	MHYT domain
IUJ48_05235	COG3121	Chaperone
IUJ48_05240	COG3188	usher protein
IUJ48_05260	COG0642	Histidine kinase
IUJ48_05265	COG1475	DNA binding
IUJ48_05275	COG3969	phosphoadenosine phosphosulfate
IUJ48_05280	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IUJ48_05340	COG2321	neutral zinc metallopeptidase
IUJ48_05345	COG0009	L-threonylcarbamoyladenylate synthase
IUJ48_05350	COG1994	Peptidase M50
IUJ48_05355	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IUJ48_05360	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
IUJ48_05370	COG2850	peptidyl-arginine hydroxylation
IUJ48_05375	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IUJ48_05435	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_05440	COG0583	DNA-binding transcription factor activity
IUJ48_05450	COG3360	Dodecin
IUJ48_05485	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IUJ48_05490	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IUJ48_05495	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IUJ48_05535	COG0668	transmembrane transport
IUJ48_05555	COG0483	inositol monophosphate 1-phosphatase activity
IUJ48_05560	COG4804	nuclease activity
IUJ48_05565	COG1477	protein flavinylation
IUJ48_05575	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
IUJ48_05590	COG4263	nitrous-oxide reductase activity
IUJ48_05605	COG1253	flavin adenine dinucleotide binding
IUJ48_05610	COG1968	undecaprenyl-diphosphatase activity
IUJ48_05615	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IUJ48_05630	COG0215	cysteine-tRNA ligase activity
IUJ48_05640	COG0825	malonyl-CoA metabolic process
IUJ48_05645	COG0037	tRNA processing
IUJ48_05650	COG0527	aspartate kinase activity
IUJ48_05680	COG0348	domain, Protein
IUJ48_05700	COG3278	Belongs to the heme-copper respiratory oxidase family
IUJ48_05715	COG3258	Cytochrome c
IUJ48_05720	COG2863	cytochrome
IUJ48_05735	COG2205	protein histidine kinase activity
IUJ48_05735	COG0784	Response regulator, receiver
IUJ48_05745	COG0784	Response regulator, receiver
IUJ48_05745	COG2205	protein histidine kinase activity
IUJ48_05755	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
IUJ48_05760	COG1051	belongs to the nudix hydrolase family
IUJ48_05770	COG1309	transcriptional regulator
IUJ48_05775	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IUJ48_05805	COG0583	DNA-binding transcription factor activity
IUJ48_05825	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IUJ48_05835	COG1414	Transcriptional regulator
IUJ48_05850	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IUJ48_05855	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IUJ48_05865	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IUJ48_05870	COG3395	kinase activity
IUJ48_05880	COG1132	(ABC) transporter
IUJ48_05890	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_05900	COG0318	PFAM AMP-dependent synthetase and ligase
IUJ48_05915	COG0183	Belongs to the thiolase family
IUJ48_05920	COG1250	3-hydroxyacyl-CoA dehydrogenase
IUJ48_05920	COG1024	Enoyl-CoA hydratase
IUJ48_05930	COG1024	Enoyl-CoA hydratase
IUJ48_05930	COG1250	3-hydroxyacyl-CoA dehydrogenase
IUJ48_05940	COG1960	acyl-CoA dehydrogenase activity
IUJ48_05945	COG1309	transcriptional regulator
IUJ48_05955	COG2197	response regulator
IUJ48_05960	COG2197	response regulator
IUJ48_05965	COG0297	glycogen (starch) synthase activity
IUJ48_05970	COG0110	maltose O-acetyltransferase activity
IUJ48_05975	COG0463	Glycosyl transferase, family 2
IUJ48_06000	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IUJ48_06020	COG1051	belongs to the nudix hydrolase family
IUJ48_06030	COG1596	polysaccharide export
IUJ48_06035	COG0489	protein tyrosine kinase activity
IUJ48_06035	COG3206	protein involved in exopolysaccharide biosynthesis
IUJ48_06040	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IUJ48_06045	COG0166	Belongs to the GPI family
IUJ48_06050	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IUJ48_06055	COG1045	serine acetyltransferase
IUJ48_06060	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IUJ48_06075	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IUJ48_06095	COG0598	Magnesium transport protein CorA
IUJ48_06110	COG0601	transmembrane transport
IUJ48_06115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IUJ48_06120	COG4172	Belongs to the ABC transporter superfamily
IUJ48_06125	COG1846	Transcriptional regulator
IUJ48_06170	COG4964	Belongs to the GSP D family
IUJ48_06225	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IUJ48_06240	COG3384	dioxygenase
IUJ48_06255	COG2814	Major facilitator Superfamily
IUJ48_06280	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IUJ48_06290	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_06320	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_06325	COG3321	synthase
IUJ48_06325	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_06325	COG0604	alcohol dehydrogenase
IUJ48_06340	COG0559	Belongs to the binding-protein-dependent transport system permease family
IUJ48_06350	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_06355	COG1250	3-hydroxyacyl-CoA dehydrogenase
IUJ48_06360	COG3246	L-lysine catabolic process to acetate
IUJ48_06365	COG0371	Dehydrogenase
IUJ48_06370	COG1802	Transcriptional regulator
IUJ48_06375	COG3959	Transketolase, thiamine diphosphate binding domain
IUJ48_06380	COG3958	Transketolase
IUJ48_06385	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IUJ48_06395	COG4948	Mandelate Racemase Muconate Lactonizing
IUJ48_06400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ48_06410	COG0765	amino acid transport
IUJ48_06420	COG2721	sulfolactate sulfo-lyase activity
IUJ48_06430	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_06435	COG0179	Fumarylacetoacetate (FAA) hydrolase
IUJ48_06440	COG1414	Transcriptional regulator
IUJ48_06455	COG0596	Alpha beta hydrolase
IUJ48_06475	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IUJ48_06485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IUJ48_06490	COG1120	ATPase activity
IUJ48_06505	COG4771	TonB-dependent receptor
IUJ48_06520	COG0477	Major facilitator Superfamily
IUJ48_06530	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IUJ48_06540	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IUJ48_06565	COG3852	Histidine kinase
IUJ48_06575	COG1058	Belongs to the CinA family
IUJ48_06575	COG1546	Belongs to the CinA family
IUJ48_06590	COG1113	amino acid transport
IUJ48_06600	COG1640	4-alpha-glucanotransferase
IUJ48_06605	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IUJ48_06615	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IUJ48_06620	COG0366	Alpha amylase catalytic
IUJ48_06625	COG0366	Alpha amylase catalytic
IUJ48_06630	COG0297	glycogen (starch) synthase activity
IUJ48_06635	COG0392	lysyltransferase activity
IUJ48_06640	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IUJ48_06645	COG3568	Endonuclease Exonuclease Phosphatase
IUJ48_06650	COG0387	Pfam Sodium calcium exchanger
IUJ48_06680	COG0166	Belongs to the GPI family
IUJ48_06690	COG0668	transmembrane transport
IUJ48_06710	COG5265	(ABC) transporter
IUJ48_06720	COG0438	transferase activity, transferring glycosyl groups
IUJ48_06725	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_06730	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IUJ48_06740	COG2192	nodulation
IUJ48_06830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IUJ48_06835	COG2207	Transcriptional regulator
IUJ48_06850	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IUJ48_06855	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IUJ48_06855	COG3608	succinylglutamate desuccinylase aspartoacylase
IUJ48_06875	COG0505	Belongs to the CarA family
IUJ48_06890	COG1850	ribulose-bisphosphate carboxylase activity
IUJ48_06900	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IUJ48_06905	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IUJ48_06910	COG1609	Transcriptional regulator
IUJ48_06925	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IUJ48_06930	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IUJ48_06935	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IUJ48_06965	COG3384	dioxygenase
IUJ48_07020	COG0583	DNA-binding transcription factor activity
IUJ48_07035	COG1024	Enoyl-CoA hydratase
IUJ48_07075	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_07090	COG1396	sequence-specific DNA binding
IUJ48_07150	COG0811	peptide transport
IUJ48_07180	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IUJ48_07200	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
IUJ48_07205	COG1116	anion transmembrane transporter activity
IUJ48_07210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IUJ48_07215	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IUJ48_07215	COG1116	anion transmembrane transporter activity
IUJ48_07220	COG2197	response regulator
IUJ48_07230	COG1131	(ABC) transporter
IUJ48_07235	COG0842	Transport permease protein
IUJ48_07250	COG0183	Belongs to the thiolase family
IUJ48_07275	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IUJ48_07280	COG0318	PFAM AMP-dependent synthetase and ligase
IUJ48_07295	COG3321	synthase
IUJ48_07295	COG0604	alcohol dehydrogenase
IUJ48_07310	COG4638	Rieske (2fe-2S)
IUJ48_07340	COG1278	Cold shock
IUJ48_07350	COG1272	protein, Hemolysin III
IUJ48_07380	COG2169	Transcriptional regulator
IUJ48_07385	COG2814	Major facilitator Superfamily
IUJ48_07390	COG0583	DNA-binding transcription factor activity
IUJ48_07400	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IUJ48_07450	COG2837	iron assimilation
IUJ48_07490	COG1250	3-hydroxyacyl-CoA dehydrogenase
IUJ48_07495	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
IUJ48_07505	COG2814	Major facilitator Superfamily
IUJ48_07520	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IUJ48_07525	COG2011	ABC-type metal ion transport system permease component
IUJ48_07560	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_07565	COG3618	amidohydrolase
IUJ48_07580	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
IUJ48_07595	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_07600	COG1473	amidohydrolase
IUJ48_07615	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_07620	COG2272	Belongs to the type-B carboxylesterase lipase family
IUJ48_07630	COG0583	DNA-binding transcription factor activity
IUJ48_07640	COG2951	lytic endotransglycosylase activity
IUJ48_07645	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IUJ48_07650	COG0519	Catalyzes the synthesis of GMP from XMP
IUJ48_07670	COG1595	DNA-templated transcription, initiation
IUJ48_07685	COG0519	Catalyzes the synthesis of GMP from XMP
IUJ48_07695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IUJ48_07710	COG4172	Belongs to the ABC transporter superfamily
IUJ48_07720	COG1522	sequence-specific DNA binding
IUJ48_07780	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IUJ48_07790	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_07815	COG0625	glutathione transferase activity
IUJ48_07830	COG3530	Putative quorum-sensing-regulated virulence factor
IUJ48_07840	COG2814	Major facilitator Superfamily
IUJ48_07875	COG0443	Heat shock 70 kDa protein
IUJ48_07880	COG0583	DNA-binding transcription factor activity
IUJ48_07885	COG0494	nUDIX hydrolase
IUJ48_07905	COG0477	Major facilitator Superfamily
IUJ48_07915	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IUJ48_07925	COG0542	response to heat
IUJ48_07950	COG5441	Belongs to the UPF0261 family
IUJ48_07955	COG5564	TIM-barrel signal transduction protein
IUJ48_07970	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
IUJ48_07985	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IUJ48_07995	COG1562	ergosterol biosynthetic process
IUJ48_08000	COG1562	ergosterol biosynthetic process
IUJ48_08005	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IUJ48_08010	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_08020	COG3971	2-oxopent-4-enoate hydratase activity
IUJ48_08035	COG1012	belongs to the aldehyde dehydrogenase family
IUJ48_08040	COG3384	dioxygenase
IUJ48_08070	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IUJ48_08080	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_08090	COG2186	Transcriptional regulator
IUJ48_08095	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
IUJ48_08100	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_08115	COG0583	DNA-binding transcription factor activity
IUJ48_08120	COG0268	Binds directly to 16S ribosomal RNA
IUJ48_08130	COG0728	peptidoglycan biosynthetic process
IUJ48_08140	COG0563	adenylate kinase activity
IUJ48_08145	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
IUJ48_08150	COG2835	tetraacyldisaccharide 4'-kinase activity
IUJ48_08160	COG1663	tetraacyldisaccharide 4'-kinase activity
IUJ48_08170	COG0811	peptide transport
IUJ48_08175	COG1570	exodeoxyribonuclease VII activity
IUJ48_08185	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IUJ48_08195	COG0038	chloride channel
IUJ48_08200	COG0183	Belongs to the thiolase family
IUJ48_08210	COG1278	Cold shock
IUJ48_08215	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IUJ48_08220	COG2373	Large extracellular alpha-helical protein
IUJ48_08225	COG4953	penicillin-binding protein 1C
IUJ48_08235	COG2995	paraquat-inducible protein a
IUJ48_08240	COG3008	intermembrane lipid transfer
IUJ48_08250	COG0506	proline dehydrogenase activity
IUJ48_08250	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IUJ48_08250	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IUJ48_08280	COG2271	Major facilitator Superfamily
IUJ48_08300	COG0625	glutathione transferase activity
IUJ48_08305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IUJ48_08315	COG1764	response to oxidative stress
IUJ48_08330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ48_08335	COG0765	amino acid transport
IUJ48_08340	COG0765	amino acid transport
IUJ48_08345	COG1126	abc transporter atp-binding protein
IUJ48_08350	COG1902	pentaerythritol trinitrate reductase activity
IUJ48_08400	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IUJ48_08405	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IUJ48_08410	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IUJ48_08415	COG0196	riboflavin kinase activity
IUJ48_08420	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IUJ48_08425	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IUJ48_08425	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IUJ48_08440	COG0210	DNA helicase
IUJ48_08450	COG1858	cytochrome C peroxidase
IUJ48_08460	COG4771	TonB-dependent receptor
IUJ48_08470	COG4771	TonB-dependent receptor
IUJ48_08475	COG4771	TonB-dependent receptor
IUJ48_08490	COG0488	(ABC) transporter
IUJ48_08495	COG2890	protein-(glutamine-N5) methyltransferase activity
IUJ48_08505	COG2171	N-acyltransferase activity
IUJ48_08585	COG1475	DNA binding
IUJ48_08600	COG3546	catalase activity
IUJ48_08605	COG3685	Protein conserved in bacteria
IUJ48_08630	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IUJ48_08730	COG0740	serine-type endopeptidase activity
IUJ48_08925	COG2814	Major facilitator Superfamily
IUJ48_08940	COG0277	FAD linked oxidase domain protein
IUJ48_08965	COG2877	3-deoxy-8-phosphooctulonate synthase activity
IUJ48_09000	COG0583	DNA-binding transcription factor activity
IUJ48_09010	COG0251	oxidation-reduction process
IUJ48_09035	COG1278	Cold shock
IUJ48_09045	COG1278	Cold shock
IUJ48_09055	COG0501	Belongs to the peptidase M48B family
IUJ48_09060	COG0544	peptidyl-prolyl cis-trans isomerase activity
IUJ48_09065	COG0740	serine-type endopeptidase activity
IUJ48_09070	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IUJ48_09075	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IUJ48_09080	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IUJ48_09090	COG0556	nucleotide-excision repair
IUJ48_09095	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IUJ48_09105	COG1104	cysteine desulfurase activity
IUJ48_09110	COG0822	iron-sulfur transferase activity
IUJ48_09115	COG0316	Belongs to the HesB IscA family
IUJ48_09120	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IUJ48_09125	COG0443	Heat shock 70 kDa protein
IUJ48_09130	COG0633	Ferredoxin
IUJ48_09135	COG2975	iron-sulfur cluster assembly
IUJ48_09140	COG1803	Methylglyoxal synthase
IUJ48_09150	COG1024	Enoyl-CoA hydratase
IUJ48_09180	COG1022	Amp-dependent synthetase and ligase
IUJ48_09185	COG0183	Belongs to the thiolase family
IUJ48_09190	COG1309	transcriptional regulator
IUJ48_09195	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IUJ48_09200	COG3135	benzoate transporter
IUJ48_09215	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IUJ48_09220	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_09230	COG2271	Major facilitator Superfamily
IUJ48_09250	COG1136	(ABC) transporter
IUJ48_09255	COG0084	hydrolase, TatD family'
IUJ48_09265	COG0745	RESPONSE REGULATOR receiver
IUJ48_09270	COG4771	TonB-dependent receptor
IUJ48_09275	COG4607	ABC-type enterochelin transport system periplasmic component
IUJ48_09280	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IUJ48_09285	COG4605	iron ion homeostasis
IUJ48_09290	COG4604	ABC transporter, ATP-binding protein
IUJ48_09305	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IUJ48_09330	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IUJ48_09335	COG4133	protoheme IX ABC transporter activity
IUJ48_09340	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_09345	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_09350	COG0633	Ferredoxin
IUJ48_09380	COG1280	lysine exporter protein (LysE YggA)
IUJ48_09390	COG3119	arylsulfatase activity
IUJ48_09405	COG2304	oxidoreductase activity
IUJ48_09425	COG0714	Associated with various cellular activities
IUJ48_09430	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IUJ48_09465	COG0459	protein refolding
IUJ48_09470	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IUJ48_09480	COG2249	NAD(P)H dehydrogenase (quinone) activity
IUJ48_09505	COG3093	addiction module antidote protein HigA
IUJ48_09515	COG2149	membrane
IUJ48_09550	COG3119	arylsulfatase activity
IUJ48_09560	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_09565	COG0277	FAD linked oxidase domain protein
IUJ48_09570	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IUJ48_09590	COG0159	tryptophan synthase activity
IUJ48_09600	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IUJ48_09605	COG0477	Major facilitator Superfamily
IUJ48_09610	COG0583	DNA-binding transcription factor activity
IUJ48_09620	COG0583	DNA-binding transcription factor activity
IUJ48_09630	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IUJ48_09645	COG0613	PHP domain protein
IUJ48_09655	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IUJ48_09660	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IUJ48_09660	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IUJ48_09670	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IUJ48_09670	COG0047	phosphoribosylformylglycinamidine synthase activity
IUJ48_09675	COG4774	siderophore transport
IUJ48_09680	COG3712	iron ion homeostasis
IUJ48_09685	COG1595	DNA-templated transcription, initiation
IUJ48_09710	COG0642	Histidine kinase
IUJ48_09725	COG0583	DNA-binding transcription factor activity
IUJ48_09735	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IUJ48_09745	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_09755	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IUJ48_09760	COG0583	DNA-binding transcription factor activity
IUJ48_09765	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_09790	COG2205	protein histidine kinase activity
IUJ48_09790	COG3292	Two component regulator propeller
IUJ48_09790	COG0745	RESPONSE REGULATOR receiver
IUJ48_09795	COG0784	Response regulator, receiver
IUJ48_09795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ48_09795	COG2198	Histidine kinase
IUJ48_09795	COG2205	protein histidine kinase activity
IUJ48_09800	COG0583	DNA-binding transcription factor activity
IUJ48_09835	COG1953	Uracil, thiamine, allantoin
IUJ48_09885	COG0583	DNA-binding transcription factor activity
IUJ48_09900	COG4774	siderophore transport
IUJ48_09905	COG4774	siderophore transport
IUJ48_09910	COG5001	Diguanylate cyclase
IUJ48_09965	COG0583	DNA-binding transcription factor activity
IUJ48_09990	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IUJ48_10040	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_10045	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
IUJ48_10050	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_10055	COG0583	DNA-binding transcription factor activity
IUJ48_10070	COG0747	negative chemotaxis
IUJ48_10075	COG4608	Belongs to the ABC transporter superfamily
IUJ48_10085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IUJ48_10090	COG0601	transmembrane transport
IUJ48_10095	COG2072	flavoprotein involved in K transport
IUJ48_10155	COG0419	ATPase involved in DNA repair
IUJ48_10160	COG2974	May be involved in recombination
IUJ48_10465	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_10470	COG0583	DNA-binding transcription factor activity
IUJ48_10500	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IUJ48_10510	COG0583	DNA-binding transcription factor activity
IUJ48_10540	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IUJ48_10540	COG0519	Catalyzes the synthesis of GMP from XMP
IUJ48_10565	COG4691	Plasmid stability protein
IUJ48_10600	COG0798	PFAM Bile acid sodium symporter
IUJ48_10650	COG0582	viral genome integration into host DNA
IUJ48_10725	COG3077	Addiction module antitoxin, RelB DinJ family
IUJ48_10735	COG1475	DNA binding
IUJ48_10745	COG5489	Protein of unknown function (DUF736)
IUJ48_10775	COG1192	Involved in chromosome partitioning
IUJ48_10800	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IUJ48_10810	COG2814	Major facilitator Superfamily
IUJ48_10835	COG0640	Transcriptional regulator
IUJ48_10840	COG1230	cation diffusion facilitator family transporter
IUJ48_10845	COG1937	Protein conserved in bacteria
IUJ48_10850	COG2814	Major facilitator Superfamily
IUJ48_10855	COG0640	Transcriptional regulator
IUJ48_10865	COG0789	Transcriptional regulator
IUJ48_10870	COG0633	Ferredoxin
IUJ48_10905	COG3621	Patatin-like phospholipase
IUJ48_10925	COG3328	transposase activity
IUJ48_10940	COG4264	IucA IucC family
IUJ48_10975	COG0431	NADPH-dependent FMN reductase
IUJ48_10980	COG0583	DNA-binding transcription factor activity
IUJ48_10985	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IUJ48_10995	COG0640	Transcriptional regulator
IUJ48_11000	COG0640	Transcriptional regulator
IUJ48_11030	COG2207	Transcriptional regulator
IUJ48_11035	COG4221	oxidoreductase activity
IUJ48_11045	COG2267	carboxylic ester hydrolase activity
IUJ48_11050	COG2207	Transcriptional regulator
IUJ48_11070	COG2205	protein histidine kinase activity
IUJ48_11085	COG0583	DNA-binding transcription factor activity
IUJ48_11100	COG0165	Argininosuccinate lyase
IUJ48_11120	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
IUJ48_11170	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_11185	COG0456	acetyltransferase
IUJ48_11215	COG0583	DNA-binding transcription factor activity
IUJ48_11230	COG0154	amidase activity
IUJ48_11235	COG0840	transmembrane signaling receptor activity
IUJ48_11260	COG2201	protein-glutamate methylesterase activity
IUJ48_11265	COG5001	Diguanylate cyclase
IUJ48_11265	COG2203	Gaf domain
IUJ48_11265	COG4251	negative regulation of phosphorylation
IUJ48_11265	COG3706	GGDEF domain
IUJ48_11270	COG4149	molybdate abc transporter
IUJ48_11275	COG1840	ABC-type Fe3 transport system, periplasmic component
IUJ48_11280	COG3842	ATPase activity
IUJ48_11285	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IUJ48_11290	COG1522	sequence-specific DNA binding
IUJ48_11300	COG2010	Cytochrome c
IUJ48_11300	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IUJ48_11305	COG1335	isochorismatase
IUJ48_11310	COG2309	aminopeptidase activity
IUJ48_11315	COG0596	Alpha beta hydrolase
IUJ48_11325	COG2080	2 iron, 2 sulfur cluster binding
IUJ48_11330	COG2010	Cytochrome c
IUJ48_11330	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IUJ48_11335	COG0477	Major facilitator Superfamily
IUJ48_11340	COG1846	Transcriptional regulator
IUJ48_11350	COG0583	DNA-binding transcription factor activity
IUJ48_11365	COG2515	1-aminocyclopropane-1-carboxylate deaminase
IUJ48_11375	COG0318	PFAM AMP-dependent synthetase and ligase
IUJ48_11380	COG1960	acyl-CoA dehydrogenase activity
IUJ48_11385	COG1960	acyl-CoA dehydrogenase activity
IUJ48_11390	COG0183	Belongs to the thiolase family
IUJ48_11395	COG1024	Enoyl-CoA hydratase
IUJ48_11395	COG1250	3-hydroxyacyl-CoA dehydrogenase
IUJ48_11400	COG0583	DNA-binding transcription factor activity
IUJ48_11425	COG0148	phosphopyruvate hydratase activity
IUJ48_11435	COG2733	membrane
IUJ48_11440	COG2032	superoxide dismutase activity
IUJ48_11445	COG0625	glutathione transferase activity
IUJ48_11625	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
IUJ48_11635	COG1360	Flagellar Motor Protein
IUJ48_11690	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IUJ48_11710	COG3541	Predicted nucleotidyltransferase
IUJ48_11715	COG1846	Transcriptional regulator
IUJ48_11745	COG0583	DNA-binding transcription factor activity
IUJ48_11755	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IUJ48_11765	COG0697	spore germination
IUJ48_11775	COG4941	Belongs to the sigma-70 factor family
IUJ48_11785	COG3795	YCII-related domain
IUJ48_11790	COG3795	YCII-related domain
IUJ48_11805	COG2885	chlorophyll binding
IUJ48_11805	COG3047	cAMP biosynthetic process
IUJ48_11825	COG2207	Transcriptional regulator
IUJ48_11835	COG1683	Conserved Protein
IUJ48_11855	COG1309	transcriptional regulator
IUJ48_11860	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_11870	COG0667	Aldo Keto reductase
IUJ48_11875	COG0477	Major facilitator Superfamily
IUJ48_11885	COG1414	Transcriptional regulator
IUJ48_11895	COG2345	Transcriptional regulator
IUJ48_11900	COG4774	siderophore transport
IUJ48_11920	COG2764	glyoxalase bleomycin resistance protein dioxygenase
IUJ48_12000	COG0840	transmembrane signaling receptor activity
IUJ48_12025	COG3038	cytochrome b561
IUJ48_12065	COG0583	DNA-binding transcription factor activity
IUJ48_12070	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_12080	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IUJ48_12090	COG0667	Aldo Keto reductase
IUJ48_12110	COG0587	DNA-directed DNA polymerase activity
IUJ48_12130	COG0833	amino acid
IUJ48_12135	COG0400	carboxylic ester hydrolase activity
IUJ48_12145	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_12155	COG0028	Belongs to the TPP enzyme family
IUJ48_12170	COG1566	PFAM secretion protein HlyD family protein
IUJ48_12180	COG1289	transmembrane transporter activity
IUJ48_12190	COG0720	synthase
IUJ48_12195	COG0602	queuosine metabolic process
IUJ48_12200	COG0513	Belongs to the DEAD box helicase family
IUJ48_12205	COG1414	Transcriptional regulator
IUJ48_12220	COG0747	negative chemotaxis
IUJ48_12225	COG0601	transmembrane transport
IUJ48_12230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IUJ48_12235	COG4172	Belongs to the ABC transporter superfamily
IUJ48_12240	COG1228	amidohydrolase
IUJ48_12245	COG0523	cobalamin synthesis protein
IUJ48_12255	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IUJ48_12260	COG0235	Class ii aldolase
IUJ48_12275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IUJ48_12280	COG1595	DNA-templated transcription, initiation
IUJ48_12285	COG3712	iron ion homeostasis
IUJ48_12300	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IUJ48_12305	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IUJ48_12310	COG4521	taurine ABC transporter
IUJ48_12315	COG0583	DNA-binding transcription factor activity
IUJ48_12340	COG1966	Carbon starvation protein
IUJ48_12345	COG2879	small protein
IUJ48_12350	COG0697	spore germination
IUJ48_12355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IUJ48_12385	COG0783	Belongs to the Dps family
IUJ48_12400	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IUJ48_12405	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IUJ48_12415	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IUJ48_12420	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
IUJ48_12425	COG0745	RESPONSE REGULATOR receiver
IUJ48_12430	COG5002	protein histidine kinase activity
IUJ48_12445	COG2070	2-Nitropropane dioxygenase
IUJ48_12465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IUJ48_12495	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_12505	COG0583	DNA-binding transcription factor activity
IUJ48_12550	COG2223	nitrite transmembrane transporter activity
IUJ48_12555	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IUJ48_12560	COG1140	nitrate reductase beta subunit
IUJ48_12565	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
IUJ48_12570	COG2181	nitrate reductase activity
IUJ48_12575	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IUJ48_12580	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IUJ48_12585	COG0288	reversible hydration of carbon dioxide
IUJ48_12590	COG1763	Mo-molybdopterin cofactor biosynthetic process
IUJ48_12595	COG3850	Histidine kinase
IUJ48_12600	COG2197	response regulator
IUJ48_12605	COG0826	peptidase U32
IUJ48_12610	COG0826	peptidase U32
IUJ48_12615	COG3154	lipid carrier protein
IUJ48_12620	COG4597	amino acid ABC transporter
IUJ48_12625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ48_12660	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IUJ48_12660	COG1116	anion transmembrane transporter activity
IUJ48_12665	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IUJ48_12670	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IUJ48_12695	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IUJ48_12710	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IUJ48_12715	COG1802	Transcriptional regulator
IUJ48_12725	COG4948	Mandelate Racemase Muconate Lactonizing
IUJ48_12765	COG0251	oxidation-reduction process
IUJ48_12790	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IUJ48_12815	COG0436	Aminotransferase
IUJ48_12820	COG0765	amino acid transport
IUJ48_12830	COG1126	abc transporter atp-binding protein
IUJ48_12850	COG0583	DNA-binding transcription factor activity
IUJ48_12880	COG4566	intracellular signal transduction
IUJ48_12885	COG4191	Histidine kinase
IUJ48_12895	COG1846	Transcriptional regulator
IUJ48_12905	COG0583	DNA-binding transcription factor activity
IUJ48_12910	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IUJ48_12935	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IUJ48_12945	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IUJ48_12950	COG2070	2-Nitropropane dioxygenase
IUJ48_12955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ48_12960	COG0765	amino acid transport
IUJ48_12965	COG1126	abc transporter atp-binding protein
IUJ48_12970	COG1120	ATPase activity
IUJ48_12975	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IUJ48_12980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IUJ48_13025	COG3486	L-lysine 6-monooxygenase (NADPH) activity
IUJ48_13035	COG0390	transport system, permease component
IUJ48_13040	COG0586	Pfam SNARE associated Golgi protein
IUJ48_13055	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IUJ48_13060	COG3842	ATPase activity
IUJ48_13065	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
IUJ48_13070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IUJ48_13080	COG0745	RESPONSE REGULATOR receiver
IUJ48_13100	COG2721	sulfolactate sulfo-lyase activity
IUJ48_13105	COG3386	PFAM SMP-30 Gluconolaconase
IUJ48_13110	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_13130	COG1276	copper resistance
IUJ48_13140	COG0519	Catalyzes the synthesis of GMP from XMP
IUJ48_13140	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IUJ48_13145	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IUJ48_13155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IUJ48_13160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IUJ48_13165	COG2358	TRAP transporter, solute receptor (TAXI family
IUJ48_13175	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IUJ48_13180	COG1335	isochorismatase
IUJ48_13185	COG0583	DNA-binding transcription factor activity
IUJ48_13195	COG0747	negative chemotaxis
IUJ48_13200	COG0601	transmembrane transport
IUJ48_13210	COG0444	Belongs to the ABC transporter superfamily
IUJ48_13230	COG0583	DNA-binding transcription factor activity
IUJ48_13235	COG0626	cystathionine gamma-synthase activity
IUJ48_13240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ48_13245	COG4597	amino acid ABC transporter
IUJ48_13250	COG0765	amino acid transport
IUJ48_13255	COG1126	abc transporter atp-binding protein
IUJ48_13275	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
IUJ48_13285	COG0640	Transcriptional regulator
IUJ48_13295	COG0798	PFAM Bile acid sodium symporter
IUJ48_13305	COG0431	NADPH-dependent FMN reductase
IUJ48_13320	COG0625	glutathione transferase activity
IUJ48_13335	COG0579	oxidoreductase
IUJ48_13345	COG0477	Major facilitator Superfamily
IUJ48_13360	COG0625	glutathione transferase activity
IUJ48_13390	COG3971	2-oxopent-4-enoate hydratase activity
IUJ48_13400	COG0446	pyridine nucleotide-disulphide oxidoreductase
IUJ48_13415	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IUJ48_13430	COG0179	Fumarylacetoacetate (FAA) hydrolase
IUJ48_13450	COG0251	oxidation-reduction process
IUJ48_13460	COG0747	negative chemotaxis
IUJ48_13465	COG0601	transmembrane transport
IUJ48_13475	COG0444	Belongs to the ABC transporter superfamily
IUJ48_13480	COG4608	Belongs to the ABC transporter superfamily
IUJ48_13485	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
IUJ48_13495	COG0531	amino acid
IUJ48_13510	COG1619	proteins homologs of microcin C7 resistance protein MccF
IUJ48_13520	COG0628	permease
IUJ48_13540	COG0793	Belongs to the peptidase S41A family
IUJ48_13565	COG4521	taurine ABC transporter
IUJ48_13570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IUJ48_13575	COG1116	anion transmembrane transporter activity
IUJ48_13605	COG3706	GGDEF domain
IUJ48_13615	COG0789	Transcriptional regulator
IUJ48_13790	COG2205	protein histidine kinase activity
IUJ48_13800	COG1253	flavin adenine dinucleotide binding
IUJ48_13835	COG4774	siderophore transport
IUJ48_13850	COG3300	MHYT domain
IUJ48_13850	COG5001	Diguanylate cyclase
IUJ48_13855	COG1289	transmembrane transporter activity
IUJ48_13865	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IUJ48_13885	COG0693	protein deglycase activity
IUJ48_13905	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_13940	COG2204	response regulator
IUJ48_13945	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
IUJ48_13970	COG2814	Major facilitator Superfamily
IUJ48_13985	COG5001	Diguanylate cyclase
IUJ48_13985	COG3300	MHYT domain
IUJ48_13990	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IUJ48_13995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IUJ48_14020	COG0488	(ABC) transporter
IUJ48_14025	COG0688	phosphatidylethanolamine metabolic process
IUJ48_14035	COG1408	metallophosphoesterase
IUJ48_14045	COG2814	Major facilitator Superfamily
IUJ48_14055	COG1464	Belongs to the NlpA lipoprotein family
IUJ48_14065	COG0010	Belongs to the arginase family
IUJ48_14085	COG2363	Small membrane protein
IUJ48_14090	COG0697	spore germination
IUJ48_14100	COG2133	pyrroloquinoline quinone binding
IUJ48_14105	COG0625	glutathione transferase activity
IUJ48_14110	COG0583	DNA-binding transcription factor activity
IUJ48_14120	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
IUJ48_14125	COG1794	racemase activity, acting on amino acids and derivatives
IUJ48_14150	COG0559	Belongs to the binding-protein-dependent transport system permease family
IUJ48_14165	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IUJ48_14175	COG1653	transport
IUJ48_14180	COG1175	transmembrane transport
IUJ48_14185	COG0395	ABC-type sugar transport system, permease component
IUJ48_14190	COG3842	ATPase activity
IUJ48_14205	COG2205	protein histidine kinase activity
IUJ48_14210	COG0745	RESPONSE REGULATOR receiver
IUJ48_14225	COG3866	Pectate lyase
IUJ48_14230	COG4783	chaperone-mediated protein folding
IUJ48_14230	COG1560	Kdo2-lipid A biosynthetic process
IUJ48_14255	COG0438	transferase activity, transferring glycosyl groups
IUJ48_14260	COG0457	Tetratricopeptide repeat
IUJ48_14270	COG0783	Belongs to the Dps family
IUJ48_14280	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IUJ48_14290	COG0583	DNA-binding transcription factor activity
IUJ48_14305	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_14315	COG1840	ABC-type Fe3 transport system, periplasmic component
IUJ48_14320	COG4149	molybdate abc transporter
IUJ48_14325	COG3842	ATPase activity
IUJ48_14330	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_14335	COG1690	Belongs to the RtcB family
IUJ48_14340	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IUJ48_14345	COG1741	Belongs to the pirin family
IUJ48_14350	COG1741	Belongs to the pirin family
IUJ48_14355	COG0583	DNA-binding transcription factor activity
IUJ48_14360	COG2204	response regulator
IUJ48_14370	COG0174	glutamine synthetase
IUJ48_14375	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IUJ48_14380	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IUJ48_14395	COG1960	acyl-CoA dehydrogenase activity
IUJ48_14405	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IUJ48_14410	COG1561	YicC-like family, N-terminal region
IUJ48_14415	COG0833	amino acid
IUJ48_14420	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IUJ48_14435	COG0791	NLP P60 protein
IUJ48_14440	COG3210	domain, Protein
IUJ48_14445	COG2831	hemolysin activation secretion protein
IUJ48_14455	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_14460	COG2863	cytochrome
IUJ48_14465	COG3258	Cytochrome c
IUJ48_14470	COG0194	GDP metabolic process
IUJ48_14475	COG1758	RNA polymerase activity
IUJ48_14480	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IUJ48_14490	COG1335	isochorismatase
IUJ48_14495	COG1126	abc transporter atp-binding protein
IUJ48_14500	COG0765	amino acid transport
IUJ48_14505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ48_14545	COG2816	NAD+ diphosphatase activity
IUJ48_14565	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IUJ48_14595	COG4336	lyase activity
IUJ48_14600	COG0583	DNA-binding transcription factor activity
IUJ48_14615	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IUJ48_14630	COG0583	DNA-binding transcription factor activity
IUJ48_14645	COG0560	Phosphoserine phosphatase
IUJ48_14650	COG0583	DNA-binding transcription factor activity
IUJ48_14655	COG3842	ATPase activity
IUJ48_14660	COG1178	ABC-type Fe3 transport system permease component
IUJ48_14670	COG4181	ATPase activity
IUJ48_14680	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IUJ48_14690	COG0584	glycerophosphoryl diester phosphodiesterase
IUJ48_14695	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IUJ48_14705	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IUJ48_14705	COG0678	peroxiredoxin activity
IUJ48_14720	COG0789	Transcriptional regulator
IUJ48_14725	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IUJ48_14730	COG2814	Major facilitator Superfamily
IUJ48_14735	COG0583	DNA-binding transcription factor activity
IUJ48_14770	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
IUJ48_14775	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IUJ48_14780	COG2252	PERMEase
IUJ48_14790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IUJ48_14795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IUJ48_14830	COG0488	(ABC) transporter
IUJ48_14835	COG1619	proteins homologs of microcin C7 resistance protein MccF
IUJ48_14855	COG1320	monovalent cation:proton antiporter activity
IUJ48_14860	COG2212	antiporter activity
IUJ48_14865	COG1863	multisubunit Na H antiporter MnhE subunit
IUJ48_14870	COG0651	ATP synthesis coupled electron transport
IUJ48_14875	COG1006	Multisubunit Na H antiporter MnhC subunit
IUJ48_14880	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IUJ48_14880	COG2111	Na H antiporter
IUJ48_14910	COG0420	3'-5' exonuclease activity
IUJ48_14915	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IUJ48_14950	COG1960	acyl-CoA dehydrogenase activity
IUJ48_14955	COG1959	2 iron, 2 sulfur cluster binding
IUJ48_14960	COG3634	alkyl hydroperoxide reductase activity
IUJ48_14980	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IUJ48_14985	COG0346	lactoylglutathione lyase activity
IUJ48_15030	COG0395	ABC-type sugar transport system, permease component
IUJ48_15040	COG3842	ATPase activity
IUJ48_15045	COG3842	ATPase activity
IUJ48_15070	COG2130	NADP-dependent
IUJ48_15085	COG1131	(ABC) transporter
IUJ48_15090	COG0842	Transport permease protein
IUJ48_15105	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IUJ48_15135	COG1902	pentaerythritol trinitrate reductase activity
IUJ48_15170	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IUJ48_15185	COG0840	transmembrane signaling receptor activity
IUJ48_15195	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IUJ48_15215	COG2814	Major facilitator Superfamily
IUJ48_15220	COG0386	Belongs to the glutathione peroxidase family
IUJ48_15225	COG1522	sequence-specific DNA binding
IUJ48_15235	COG0625	glutathione transferase activity
IUJ48_15250	COG0095	Lipoate-protein ligase
IUJ48_15260	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IUJ48_15270	COG0010	Belongs to the arginase family
IUJ48_15275	COG1126	abc transporter atp-binding protein
IUJ48_15280	COG0765	amino acid transport
IUJ48_15285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ48_15300	COG0084	hydrolase, TatD family'
IUJ48_15305	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IUJ48_15310	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IUJ48_15315	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IUJ48_15340	COG1250	3-hydroxyacyl-CoA dehydrogenase
IUJ48_15340	COG1024	Enoyl-CoA hydratase
IUJ48_15350	COG2914	Belongs to the UPF0125 (RnfH) family
IUJ48_15355	COG2867	negative regulation of translational initiation
IUJ48_15360	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IUJ48_15380	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IUJ48_15380	COG0519	Catalyzes the synthesis of GMP from XMP
IUJ48_15385	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IUJ48_15385	COG2169	Transcriptional regulator
IUJ48_15405	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IUJ48_15410	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IUJ48_15425	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IUJ48_15430	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IUJ48_15435	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
IUJ48_15440	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IUJ48_15445	COG0750	zinc metalloprotease
IUJ48_15450	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
IUJ48_15460	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IUJ48_15465	COG0233	cytoplasmic translational termination
IUJ48_15470	COG0528	UMP kinase activity
IUJ48_15475	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IUJ48_15480	COG0052	Belongs to the universal ribosomal protein uS2 family
IUJ48_15485	COG0024	Methionine aminopeptidase
IUJ48_15490	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
IUJ48_15500	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
IUJ48_15505	COG1451	nucleotide metabolic process
IUJ48_15525	COG0285	dihydrofolate synthase activity
IUJ48_15535	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_15540	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IUJ48_15550	COG1414	Transcriptional regulator
IUJ48_15555	COG1334	flagellar protein FlaG
IUJ48_15560	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IUJ48_15580	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IUJ48_15590	COG1677	Flagellar hook-basal body complex protein FliE
IUJ48_15595	COG1766	The M ring may be actively involved in energy transduction
IUJ48_15600	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IUJ48_15625	COG1580	Controls the rotational direction of flagella during chemotaxis
IUJ48_15635	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IUJ48_15660	COG0840	transmembrane signaling receptor activity
IUJ48_15665	COG0840	transmembrane signaling receptor activity
IUJ48_15675	COG0840	transmembrane signaling receptor activity
IUJ48_15680	COG0840	transmembrane signaling receptor activity
IUJ48_15715	COG4787	bacterial-type flagellum-dependent cell motility
IUJ48_15730	COG1558	bacterial-type flagellum-dependent cell motility
IUJ48_15735	COG1815	bacterial-type flagellum-dependent cell motility
IUJ48_15745	COG2747	anti-sigma28 factor FlgM
IUJ48_15770	COG0840	transmembrane signaling receptor activity
IUJ48_15775	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
IUJ48_15780	COG0745	RESPONSE REGULATOR receiver
IUJ48_15785	COG2201	protein-glutamate methylesterase activity
IUJ48_15790	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IUJ48_15795	COG0840	transmembrane signaling receptor activity
IUJ48_15800	COG0835	chemotaxis
IUJ48_15810	COG0745	RESPONSE REGULATOR receiver
IUJ48_15815	COG1360	Flagellar Motor Protein
IUJ48_15835	COG1191	sigma factor activity
IUJ48_15840	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IUJ48_15840	COG4797	methyltransferase
IUJ48_15860	COG0583	DNA-binding transcription factor activity
IUJ48_15870	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IUJ48_15875	COG0508	dehydrogenase complex catalyzes the overall conversion of
IUJ48_15880	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
IUJ48_15890	COG4566	intracellular signal transduction
IUJ48_15895	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IUJ48_15900	COG0339	signal peptide processing
IUJ48_15910	COG1999	signal sequence binding
IUJ48_15935	COG0583	DNA-binding transcription factor activity
IUJ48_15940	COG1187	pseudouridine synthase activity
IUJ48_15945	COG3161	chorismate lyase activity
IUJ48_15950	COG0477	Major facilitator Superfamily
IUJ48_15965	COG4681	YaeQ
IUJ48_15970	COG4172	Belongs to the ABC transporter superfamily
IUJ48_15975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IUJ48_15980	COG0601	transmembrane transport
IUJ48_15985	COG0747	negative chemotaxis
IUJ48_15995	COG0583	DNA-binding transcription factor activity
IUJ48_16025	COG2165	general secretion pathway protein
IUJ48_16095	COG0668	transmembrane transport
IUJ48_16100	COG0165	Argininosuccinate lyase
IUJ48_16120	COG0022	dehydrogenase e1 component
IUJ48_16130	COG4774	siderophore transport
IUJ48_16155	COG0789	Transcriptional regulator
IUJ48_16165	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IUJ48_16175	COG2271	Major facilitator Superfamily
IUJ48_16185	COG0307	riboflavin synthase, alpha
IUJ48_16190	COG1012	belongs to the aldehyde dehydrogenase family
IUJ48_16200	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_16220	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IUJ48_16255	COG0154	amidase activity
IUJ48_16260	COG2814	Major facilitator Superfamily
IUJ48_16270	COG2226	methyltransferase
IUJ48_16295	COG0583	DNA-binding transcription factor activity
IUJ48_16305	COG0583	DNA-binding transcription factor activity
IUJ48_16315	COG0583	DNA-binding transcription factor activity
IUJ48_16320	COG1132	(ABC) transporter
IUJ48_16350	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_16355	COG0318	PFAM AMP-dependent synthetase and ligase
IUJ48_16370	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IUJ48_16380	COG5265	(ABC) transporter
IUJ48_16385	COG1280	lysine exporter protein (LysE YggA)
IUJ48_16425	COG0318	PFAM AMP-dependent synthetase and ligase
IUJ48_16430	COG2188	Transcriptional regulator
IUJ48_16445	COG0477	Major facilitator Superfamily
IUJ48_16450	COG0235	Class ii aldolase
IUJ48_16490	COG2610	gluconate transmembrane transporter activity
IUJ48_16495	COG0583	DNA-binding transcription factor activity
IUJ48_16500	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_16505	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
IUJ48_16545	COG1024	Enoyl-CoA hydratase
IUJ48_16550	COG5001	Diguanylate cyclase
IUJ48_16555	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_16560	COG0129	dihydroxy-acid dehydratase activity
IUJ48_16570	COG0583	DNA-binding transcription factor activity
IUJ48_16575	COG1250	3-hydroxyacyl-CoA dehydrogenase
IUJ48_16580	COG3246	L-lysine catabolic process to acetate
IUJ48_16600	COG3043	anaerobic respiration
IUJ48_16605	COG3005	denitrification pathway
IUJ48_16610	COG4133	protoheme IX ABC transporter activity
IUJ48_16630	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
IUJ48_16640	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IUJ48_16650	COG4235	cytochrome complex assembly
IUJ48_16670	COG3381	protein complex oligomerization
IUJ48_16690	COG4133	protoheme IX ABC transporter activity
IUJ48_16710	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
IUJ48_16720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IUJ48_16725	COG3088	subunit of a heme lyase
IUJ48_16745	COG1716	ATPase activity
IUJ48_16745	COG5001	Diguanylate cyclase
IUJ48_16760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ48_16760	COG2205	protein histidine kinase activity
IUJ48_16765	COG0784	Response regulator, receiver
IUJ48_16765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ48_16765	COG2198	Histidine kinase
IUJ48_16765	COG2205	protein histidine kinase activity
IUJ48_16775	COG3121	Chaperone
IUJ48_16805	COG1595	DNA-templated transcription, initiation
IUJ48_16810	COG3712	iron ion homeostasis
IUJ48_16830	COG1304	FMN binding
IUJ48_16840	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IUJ48_16845	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IUJ48_16850	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_16855	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_16870	COG2207	Transcriptional regulator
IUJ48_16905	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_16915	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
IUJ48_16920	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IUJ48_16930	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_16935	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IUJ48_16940	COG0534	Mate efflux family protein
IUJ48_16955	COG0697	spore germination
IUJ48_16960	COG0697	spore germination
IUJ48_16975	COG1280	lysine exporter protein (LysE YggA)
IUJ48_16990	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
IUJ48_16995	COG3245	cytochrome
IUJ48_17035	COG0318	PFAM AMP-dependent synthetase and ligase
IUJ48_17040	COG1960	acyl-CoA dehydrogenase activity
IUJ48_17055	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IUJ48_17060	COG2814	Major facilitator Superfamily
IUJ48_17075	COG0625	glutathione transferase activity
IUJ48_17080	COG0583	DNA-binding transcription factor activity
IUJ48_17085	COG0583	DNA-binding transcription factor activity
IUJ48_17105	COG0506	proline dehydrogenase activity
IUJ48_17110	COG0697	spore germination
IUJ48_17115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IUJ48_17145	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IUJ48_17150	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IUJ48_17160	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IUJ48_17200	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_17205	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IUJ48_17210	COG1610	YqeY-like protein
IUJ48_17240	COG0457	Tetratricopeptide repeat
IUJ48_17245	COG0726	polysaccharide deacetylase
IUJ48_17245	COG1649	PFAM Uncharacterised BCR, COG1649
IUJ48_17250	COG1215	transferase activity, transferring glycosyl groups
IUJ48_17260	COG2223	nitrite transmembrane transporter activity
IUJ48_17265	COG1917	Cupin 2, conserved barrel domain protein
IUJ48_17265	COG4977	sequence-specific DNA binding
IUJ48_17275	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IUJ48_17290	COG0656	L-ascorbic acid biosynthetic process
IUJ48_17295	COG5265	(ABC) transporter
IUJ48_17325	COG1116	anion transmembrane transporter activity
IUJ48_17350	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_17355	COG0583	DNA-binding transcription factor activity
IUJ48_17385	COG1522	sequence-specific DNA binding
IUJ48_17420	COG0456	acetyltransferase
IUJ48_17425	COG0384	phenazine biosynthesis protein PhzF
IUJ48_17450	COG2814	Major facilitator Superfamily
IUJ48_17480	COG0072	phenylalanine-tRNA ligase activity
IUJ48_17480	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IUJ48_17485	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IUJ48_17490	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IUJ48_17495	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IUJ48_17505	COG2960	long-chain fatty acid transporting porin activity
IUJ48_17515	COG0347	Belongs to the P(II) protein family
IUJ48_17520	COG0004	ammonium transporteR
IUJ48_17525	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IUJ48_17530	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IUJ48_17545	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IUJ48_17550	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IUJ48_17560	COG2197	response regulator
IUJ48_17565	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IUJ48_17595	COG1012	belongs to the aldehyde dehydrogenase family
IUJ48_17605	COG0601	transmembrane transport
IUJ48_17610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IUJ48_17615	COG4172	Belongs to the ABC transporter superfamily
IUJ48_17635	COG1609	Transcriptional regulator
IUJ48_17640	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IUJ48_17645	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IUJ48_17650	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IUJ48_17655	COG0129	dihydroxy-acid dehydratase activity
IUJ48_17690	COG0596	Alpha beta hydrolase
IUJ48_17710	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IUJ48_17715	COG0101	tRNA pseudouridine synthase activity
IUJ48_17725	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IUJ48_17745	COG1538	Outer membrane efflux protein
IUJ48_17760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IUJ48_17790	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IUJ48_17815	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IUJ48_17825	COG1295	ribonuclease BN
IUJ48_17835	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IUJ48_17865	COG4964	Belongs to the GSP D family
IUJ48_17895	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IUJ48_17895	COG2755	lipolytic protein G-D-S-L family
IUJ48_17905	COG0438	transferase activity, transferring glycosyl groups
IUJ48_17925	COG0828	Belongs to the bacterial ribosomal protein bS21 family
IUJ48_17930	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
IUJ48_17935	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IUJ48_17940	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IUJ48_17945	COG0330	HflC and HflK could
IUJ48_17950	COG0330	HflC and HflK could
IUJ48_17955	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IUJ48_17960	COG1923	regulation of RNA biosynthetic process
IUJ48_17965	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IUJ48_17970	COG1160	GTP binding
IUJ48_17975	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IUJ48_17980	COG2976	Protein conserved in bacteria
IUJ48_18005	COG0105	UTP biosynthetic process
IUJ48_18010	COG0525	valine-tRNA ligase activity
IUJ48_18015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IUJ48_18020	COG1126	abc transporter atp-binding protein
IUJ48_18025	COG0765	amino acid transport
IUJ48_18030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ48_18035	COG1396	sequence-specific DNA binding
IUJ48_18040	COG0336	Belongs to the RNA methyltransferase TrmD family
IUJ48_18050	COG0228	four-way junction DNA binding
IUJ48_18060	COG0425	Belongs to the sulfur carrier protein TusA family
IUJ48_18065	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IUJ48_18080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IUJ48_18095	COG2076	Multidrug Resistance protein
IUJ48_18100	COG0633	Ferredoxin
IUJ48_18100	COG3217	Mosc domain protein beta barrel domain protein
IUJ48_18105	COG5285	phytanoyl-CoA dioxygenase
IUJ48_18110	COG0662	Cupin 2, conserved barrel domain protein
IUJ48_18135	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IUJ48_18140	COG2311	Membrane
IUJ48_18145	COG1309	transcriptional regulator
IUJ48_18170	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IUJ48_18180	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IUJ48_18185	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IUJ48_18205	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IUJ48_18215	COG3391	amine dehydrogenase activity
IUJ48_18245	COG1846	Transcriptional regulator
IUJ48_18255	COG1566	PFAM secretion protein HlyD family protein
IUJ48_18260	COG2814	Major facilitator Superfamily
IUJ48_18270	COG0473	3-isopropylmalate dehydrogenase activity
IUJ48_18275	COG0433	COG0433 Predicted ATPase
IUJ48_18280	COG0217	transcriptional regulatory protein
IUJ48_18285	COG0151	Belongs to the GarS family
IUJ48_18295	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IUJ48_18300	COG0799	negative regulation of ribosome biogenesis
IUJ48_18305	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IUJ48_18315	COG1301	dicarboxylic acid transport
IUJ48_18320	COG4191	Histidine kinase
IUJ48_18325	COG2204	response regulator
IUJ48_18355	COG1530	ribonuclease E activity
IUJ48_18365	COG5001	Diguanylate cyclase
IUJ48_18365	COG4251	negative regulation of phosphorylation
IUJ48_18365	COG2203	Gaf domain
IUJ48_18365	COG3706	GGDEF domain
IUJ48_18375	COG0475	glutathione-regulated potassium exporter activity
IUJ48_18375	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IUJ48_18380	COG1132	(ABC) transporter
IUJ48_18405	COG0726	polysaccharide deacetylase
IUJ48_18420	COG0726	polysaccharide deacetylase
IUJ48_18425	COG0438	transferase activity, transferring glycosyl groups
IUJ48_18440	COG1116	anion transmembrane transporter activity
IUJ48_18445	COG0395	ABC-type sugar transport system, permease component
IUJ48_18450	COG1643	Atp-dependent helicase
IUJ48_18455	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IUJ48_18455	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IUJ48_18460	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
IUJ48_18470	COG0704	Plays a role in the regulation of phosphate uptake
IUJ48_18480	COG1960	acyl-CoA dehydrogenase activity
IUJ48_18490	COG1322	Protein conserved in bacteria
IUJ48_18510	COG1177	transmembrane transport
IUJ48_18515	COG1176	ABC-type spermidine putrescine transport system, permease component I
IUJ48_18520	COG3842	ATPase activity
IUJ48_18530	COG3642	lipopolysaccharide core region biosynthetic process
IUJ48_18540	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
IUJ48_18545	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IUJ48_18555	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IUJ48_18555	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IUJ48_18565	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IUJ48_18570	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IUJ48_18575	COG2945	thiolester hydrolase activity
IUJ48_18575	COG0596	Alpha beta hydrolase
IUJ48_18595	COG3618	amidohydrolase
IUJ48_18600	COG0583	DNA-binding transcription factor activity
IUJ48_18605	COG0137	argininosuccinate synthase activity
IUJ48_18610	COG3158	transport of potassium into the cell
IUJ48_18615	COG0642	Histidine kinase
IUJ48_18645	COG0776	regulation of translation
IUJ48_18650	COG3128	pkhd-type hydroxylase
IUJ48_18660	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IUJ48_18665	COG0557	exoribonuclease II activity
IUJ48_18695	COG0679	Auxin Efflux Carrier
IUJ48_18700	COG2391	methyltransferase activity
IUJ48_18705	COG0069	glutamate synthase activity
IUJ48_18710	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IUJ48_18720	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
IUJ48_18755	COG0697	spore germination
IUJ48_18870	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
IUJ48_18880	COG0628	permease
IUJ48_18910	COG3909	cytochrome
IUJ48_18920	COG0625	glutathione transferase activity
IUJ48_18925	COG0730	response to heat
IUJ48_18930	COG0482	sulfurtransferase activity
IUJ48_18935	COG0583	DNA-binding transcription factor activity
IUJ48_18965	COG0247	lactate metabolic process
IUJ48_18970	COG0277	FAD linked oxidase domain protein
IUJ48_18975	COG0277	FAD linked oxidase domain protein
IUJ48_18980	COG0277	FAD linked oxidase domain protein
IUJ48_18985	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IUJ48_18990	COG0312	modulator of DNA gyrase
IUJ48_19005	COG0308	aminopeptidase N
IUJ48_19010	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
IUJ48_19030	COG0436	Aminotransferase
IUJ48_19040	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IUJ48_19045	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
IUJ48_19065	COG0559	Belongs to the binding-protein-dependent transport system permease family
IUJ48_19095	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_19105	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IUJ48_19125	COG0181	hydroxymethylbilane synthase activity
IUJ48_19130	COG0861	Integral membrane protein TerC family
IUJ48_19135	COG0861	Integral membrane protein TerC family
IUJ48_19140	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IUJ48_19145	COG0045	succinate-CoA ligase (ADP-forming) activity
IUJ48_19170	COG2137	regulation of response to DNA damage stimulus
IUJ48_19175	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IUJ48_19210	COG0540	Belongs to the ATCase OTCase family
IUJ48_19260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IUJ48_19295	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IUJ48_19305	COG0305	Participates in initiation and elongation during chromosome replication
IUJ48_19315	COG0359	binds to the 23S rRNA
IUJ48_19320	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IUJ48_19325	COG2965	DNA replication, synthesis of RNA primer
IUJ48_19330	COG0360	Binds together with S18 to 16S ribosomal RNA
IUJ48_19335	COG3739	integral membrane protein
IUJ48_19340	COG1469	GTP cyclohydrolase I activity
IUJ48_19350	COG0142	geranyltranstransferase activity
IUJ48_19355	COG1722	exodeoxyribonuclease VII activity
IUJ48_19365	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_19385	COG1840	ABC-type Fe3 transport system, periplasmic component
IUJ48_19390	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IUJ48_19400	COG3842	ATPase activity
IUJ48_19405	COG0583	DNA-binding transcription factor activity
IUJ48_19425	COG0501	Belongs to the peptidase M48B family
IUJ48_19430	COG1760	l-serine dehydratase
IUJ48_19440	COG0412	Dienelactone hydrolase
IUJ48_19455	COG1611	Belongs to the LOG family
IUJ48_19460	COG1473	amidohydrolase
IUJ48_19465	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_19485	COG1217	gtp-binding protein TYPA
IUJ48_19490	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IUJ48_19495	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IUJ48_19500	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IUJ48_19505	COG2251	uridine kinase activity
IUJ48_19505	COG0195	Participates in both transcription termination and antitermination
IUJ48_19510	COG0779	Required for maturation of 30S ribosomal subunits
IUJ48_19515	COG1187	pseudouridine synthase activity
IUJ48_19520	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IUJ48_19535	COG0583	DNA-binding transcription factor activity
IUJ48_19540	COG0523	cobalamin synthesis protein
IUJ48_19545	COG0523	cobalamin synthesis protein
IUJ48_19565	COG0642	Histidine kinase
IUJ48_19570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IUJ48_19575	COG0625	glutathione transferase activity
IUJ48_19580	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IUJ48_19590	COG2003	Belongs to the UPF0758 family
IUJ48_19595	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
IUJ48_19600	COG3483	tryptophan 2,3-dioxygenase activity
IUJ48_19615	COG0534	Mate efflux family protein
IUJ48_19625	COG2050	protein possibly involved in aromatic compounds catabolism
IUJ48_19630	COG1024	Enoyl-CoA hydratase
IUJ48_19635	COG1012	belongs to the aldehyde dehydrogenase family
IUJ48_19640	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IUJ48_19645	COG2151	metal-sulfur cluster biosynthetic enzyme
IUJ48_19650	COG3396	Phenylacetate-CoA oxygenase
IUJ48_19655	COG3460	Phenylacetate-CoA oxygenase
IUJ48_19660	COG3396	Phenylacetate-CoA oxygenase
IUJ48_19665	COG3327	negative regulation of DNA-templated transcription, initiation
IUJ48_19670	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IUJ48_19675	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IUJ48_19680	COG0501	Belongs to the peptidase M48B family
IUJ48_19685	COG1162	GTPase activity
IUJ48_19690	COG0494	nUDIX hydrolase
IUJ48_19695	COG0335	large ribosomal subunit rRNA binding
IUJ48_19730	COG4208	sulfate ABC transporter
IUJ48_19735	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IUJ48_19745	COG0450	alkyl hydroperoxide reductase
IUJ48_19750	COG1960	acyl-CoA dehydrogenase activity
IUJ48_19755	COG2985	domain, Protein
IUJ48_19780	COG0123	including yeast histone deacetylase and acetoin utilization protein
IUJ48_19785	COG2951	lytic endotransglycosylase activity
IUJ48_19815	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IUJ48_19820	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
IUJ48_19825	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
IUJ48_19845	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IUJ48_19850	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IUJ48_19860	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IUJ48_19870	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IUJ48_19885	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IUJ48_19910	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IUJ48_19920	COG1215	transferase activity, transferring glycosyl groups
IUJ48_19940	COG1696	Membrane protein involved in D-alanine export
IUJ48_19950	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IUJ48_19960	COG1960	acyl-CoA dehydrogenase activity
IUJ48_19975	COG2951	lytic endotransglycosylase activity
IUJ48_19980	COG2258	MOSC domain
IUJ48_19985	COG2833	Protein of unknown function (DUF455)
IUJ48_20000	COG1132	(ABC) transporter
IUJ48_20005	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IUJ48_20005	COG0189	ligase activity
IUJ48_20010	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IUJ48_20010	COG0189	ligase activity
IUJ48_20015	COG3237	CsbD-like
IUJ48_20025	COG2823	Periplasmic or secreted lipoprotein
IUJ48_20045	COG3210	domain, Protein
IUJ48_20050	COG2831	hemolysin activation secretion protein
IUJ48_20075	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
IUJ48_20080	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_20085	COG3243	poly(R)-hydroxyalkanoic acid synthase
IUJ48_20090	COG1496	oxidoreductase activity
IUJ48_20095	COG0564	pseudouridine synthase activity
IUJ48_20105	COG1199	ATP-dependent helicase activity
IUJ48_20110	COG2183	response to ionizing radiation
IUJ48_20145	COG4774	siderophore transport
IUJ48_20150	COG3712	iron ion homeostasis
IUJ48_20155	COG1595	DNA-templated transcription, initiation
IUJ48_20160	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IUJ48_20165	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IUJ48_20170	COG0508	dehydrogenase complex catalyzes the overall conversion of
IUJ48_20175	COG0567	Dehydrogenase, E1 component
IUJ48_20180	COG1522	sequence-specific DNA binding
IUJ48_20185	COG2515	1-aminocyclopropane-1-carboxylate deaminase
IUJ48_20200	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IUJ48_20205	COG1297	OPT oligopeptide transporter protein
IUJ48_20215	COG0281	malic enzyme
IUJ48_20215	COG0280	phosphate acetyltransferase
IUJ48_20230	COG0372	Belongs to the citrate synthase family
IUJ48_20235	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IUJ48_20240	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IUJ48_20245	COG1053	succinate dehydrogenase
IUJ48_20250	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IUJ48_20255	COG2009	succinate dehydrogenase
IUJ48_20260	COG2188	Transcriptional regulator
IUJ48_20265	COG0039	L-malate dehydrogenase activity
IUJ48_20285	COG1981	membrane
IUJ48_20320	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IUJ48_20330	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IUJ48_20345	COG0148	phosphopyruvate hydratase activity
IUJ48_20355	COG0504	CTP synthase activity
IUJ48_20390	COG0747	negative chemotaxis
IUJ48_20395	COG4172	Belongs to the ABC transporter superfamily
IUJ48_20400	COG1446	asparaginase
IUJ48_20410	COG2153	protein acetylation
IUJ48_20435	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IUJ48_20455	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IUJ48_20460	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
IUJ48_20465	COG0697	spore germination
IUJ48_20470	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IUJ48_20480	COG3193	protein, possibly involved in utilization of glycolate and propanediol
IUJ48_20490	COG0791	NLP P60 protein
IUJ48_20500	COG0583	DNA-binding transcription factor activity
IUJ48_20525	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IUJ48_20575	COG1381	Involved in DNA repair and RecF pathway recombination
IUJ48_20580	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IUJ48_20585	COG0571	ribonuclease III activity
IUJ48_20590	COG0681	Belongs to the peptidase S26 family
IUJ48_20595	COG0481	GTPase activity
IUJ48_20600	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IUJ48_20625	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IUJ48_20630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IUJ48_20640	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IUJ48_20645	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IUJ48_20655	COG0333	Belongs to the bacterial ribosomal protein bL32 family
IUJ48_20665	COG0424	maF-like protein
IUJ48_20680	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
IUJ48_20685	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IUJ48_20690	COG0546	phosphoglycolate phosphatase activity
IUJ48_20695	COG0564	pseudouridine synthase activity
IUJ48_20700	COG1530	ribonuclease E activity
IUJ48_20705	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IUJ48_20710	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IUJ48_20715	COG0159	tryptophan synthase activity
IUJ48_20725	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IUJ48_20735	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IUJ48_20740	COG3228	Belongs to the MtfA family
IUJ48_20750	COG0251	oxidation-reduction process
IUJ48_20755	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IUJ48_20760	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IUJ48_20775	COG2878	Part of a membrane complex involved in electron transport
IUJ48_20780	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IUJ48_20815	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IUJ48_20850	COG1268	BioY protein
IUJ48_20855	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IUJ48_20860	COG1122	ATPase activity
IUJ48_20865	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IUJ48_20870	COG2917	probably involved in intracellular septation
IUJ48_20880	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IUJ48_20885	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IUJ48_20895	COG1196	nuclear chromosome segregation
IUJ48_20900	COG0477	Major facilitator Superfamily
IUJ48_20905	COG1573	uracil-dna glycosylase
IUJ48_20910	COG1214	PFAM Peptidase M22, glycoprotease
IUJ48_20925	COG0450	alkyl hydroperoxide reductase
IUJ48_20930	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IUJ48_20940	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
IUJ48_20945	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IUJ48_20950	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IUJ48_20955	COG0560	Phosphoserine phosphatase
IUJ48_20960	COG4774	siderophore transport
IUJ48_20965	COG4774	siderophore transport
IUJ48_20975	COG1007	ATP synthesis coupled electron transport
IUJ48_20990	COG0713	ATP synthesis coupled electron transport
IUJ48_21000	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IUJ48_21005	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IUJ48_21010	COG1034	ATP synthesis coupled electron transport
IUJ48_21020	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
IUJ48_21025	COG0649	NAD binding
IUJ48_21030	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IUJ48_21035	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IUJ48_21040	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IUJ48_21045	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IUJ48_21070	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IUJ48_21090	COG0583	DNA-binding transcription factor activity
IUJ48_21095	COG1309	transcriptional regulator
IUJ48_21105	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IUJ48_21125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IUJ48_21130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IUJ48_21135	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IUJ48_21145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IUJ48_21150	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IUJ48_21170	COG0747	negative chemotaxis
IUJ48_21180	COG4172	Belongs to the ABC transporter superfamily
IUJ48_21200	COG1522	sequence-specific DNA binding
IUJ48_21205	COG4772	TonB-dependent receptor
IUJ48_21210	COG2354	Protein conserved in bacteria
IUJ48_21215	COG3813	Protein conserved in bacteria
IUJ48_21220	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
IUJ48_21225	COG3604	Transcriptional regulator
IUJ48_21240	COG4191	Histidine kinase
IUJ48_21240	COG0784	Response regulator, receiver
IUJ48_21245	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IUJ48_21265	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_21270	COG2851	Citrate transporter
IUJ48_21280	COG0642	Histidine kinase
IUJ48_21300	COG3712	iron ion homeostasis
IUJ48_21305	COG1595	DNA-templated transcription, initiation
IUJ48_21320	COG1116	anion transmembrane transporter activity
IUJ48_21355	COG1910	domain protein
IUJ48_21375	COG0840	transmembrane signaling receptor activity
IUJ48_21400	COG2885	chlorophyll binding
IUJ48_21400	COG3047	cAMP biosynthetic process
IUJ48_21415	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IUJ48_21420	COG0149	triose-phosphate isomerase activity
IUJ48_21445	COG2207	Transcriptional regulator
IUJ48_21465	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IUJ48_21475	COG1185	polyribonucleotide nucleotidyltransferase activity
IUJ48_21480	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IUJ48_21490	COG1183	phosphatidylcholine synthase activity
IUJ48_21495	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IUJ48_21500	COG0440	acetolactate synthase activity
IUJ48_21505	COG0028	Belongs to the TPP enzyme family
IUJ48_21510	COG1289	transmembrane transporter activity
IUJ48_21515	COG3022	response to hydroperoxide
IUJ48_21520	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_21540	COG1132	(ABC) transporter
IUJ48_21540	COG2375	cellular response to nickel ion
IUJ48_21545	COG1132	(ABC) transporter
IUJ48_21550	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IUJ48_21555	COG4605	iron ion homeostasis
IUJ48_21560	COG4604	ABC transporter, ATP-binding protein
IUJ48_21565	COG4607	ABC-type enterochelin transport system periplasmic component
IUJ48_21570	COG4774	siderophore transport
IUJ48_21580	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IUJ48_21620	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IUJ48_21625	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IUJ48_21630	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IUJ48_21645	COG0601	transmembrane transport
IUJ48_21665	COG0517	IMP dehydrogenase activity
IUJ48_21665	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IUJ48_21670	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
IUJ48_21675	COG0251	oxidation-reduction process
IUJ48_21680	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IUJ48_21685	COG1674	ftsk spoiiie
IUJ48_21690	COG0492	ferredoxin-NADP+ reductase activity
IUJ48_21695	COG1193	negative regulation of DNA recombination
IUJ48_21705	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IUJ48_21720	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IUJ48_21725	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IUJ48_21730	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
IUJ48_21735	COG2205	protein histidine kinase activity
IUJ48_21740	COG0745	RESPONSE REGULATOR receiver
IUJ48_21755	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IUJ48_21760	COG0840	transmembrane signaling receptor activity
IUJ48_21795	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IUJ48_21820	COG0612	Peptidase, M16
IUJ48_21830	COG0484	heat shock protein binding
IUJ48_21835	COG0443	Heat shock 70 kDa protein
IUJ48_21845	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IUJ48_21855	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
IUJ48_21860	COG1420	regulation of RNA biosynthetic process
IUJ48_21870	COG0497	DNA recombination
IUJ48_21875	COG0735	belongs to the Fur family
IUJ48_21880	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IUJ48_21905	COG0582	viral genome integration into host DNA
IUJ48_21910	COG0583	DNA-binding transcription factor activity
IUJ48_21920	COG1021	2,3-dihydroxybenzoate-AMP ligase
IUJ48_21940	COG3433	isochorismatase activity
IUJ48_21940	COG2226	methyltransferase
IUJ48_21940	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IUJ48_21980	COG4106	trans-aconitate 2-methyltransferase activity
IUJ48_21990	COG2814	Major facilitator Superfamily
IUJ48_21995	COG2375	cellular response to nickel ion
IUJ48_21995	COG1132	(ABC) transporter
IUJ48_22005	COG4771	TonB-dependent receptor
IUJ48_22035	COG0640	Transcriptional regulator
IUJ48_22040	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IUJ48_22100	COG4774	siderophore transport
IUJ48_22110	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IUJ48_22115	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IUJ48_22130	COG0019	diaminopimelate decarboxylase activity
IUJ48_22140	COG1131	(ABC) transporter
IUJ48_22170	COG4771	TonB-dependent receptor
IUJ48_22185	COG2807	transmembrane transport
IUJ48_22205	COG0024	Methionine aminopeptidase
IUJ48_22220	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IUJ48_22335	COG3311	Transcriptional regulator
IUJ48_22340	COG1569	PIN domain
IUJ48_22345	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IUJ48_22440	COG3344	reverse transcriptase
IUJ48_22465	COG3344	reverse transcriptase
IUJ48_22535	COG0789	Transcriptional regulator
IUJ48_22580	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IUJ48_22590	COG0789	Transcriptional regulator
IUJ48_22605	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IUJ48_22610	COG0629	single-stranded DNA binding
IUJ48_22700	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IUJ48_22705	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
IUJ48_22710	COG0167	dihydroorotate dehydrogenase activity
IUJ48_22725	COG1414	Transcriptional regulator
IUJ48_22730	COG1546	Belongs to the CinA family
IUJ48_22730	COG1058	Belongs to the CinA family
IUJ48_22745	COG0513	Belongs to the DEAD box helicase family
IUJ48_22755	COG4771	TonB-dependent receptor
IUJ48_22760	COG2814	Major facilitator Superfamily
IUJ48_22800	COG4783	chaperone-mediated protein folding
IUJ48_22815	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IUJ48_22820	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IUJ48_22835	COG0006	proline dipeptidase activity
IUJ48_22845	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IUJ48_22870	COG0632	four-way junction helicase activity
IUJ48_22875	COG1090	epimerase
IUJ48_22885	COG2255	four-way junction helicase activity
IUJ48_22890	COG4191	Histidine kinase
IUJ48_22905	COG0514	ATP-dependent DNA helicase (RecQ)
IUJ48_22910	COG1294	oxidase, subunit
IUJ48_22920	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IUJ48_22925	COG0850	regulation of cytokinetic process
IUJ48_22930	COG2894	cell division
IUJ48_22935	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
IUJ48_22960	COG0488	(ABC) transporter
IUJ48_22965	COG2746	aminoglycoside 3-N-acetyltransferase activity
IUJ48_22985	COG4608	Belongs to the ABC transporter superfamily
IUJ48_22990	COG0444	Belongs to the ABC transporter superfamily
IUJ48_22995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IUJ48_23000	COG0601	transmembrane transport
IUJ48_23005	COG0747	negative chemotaxis
IUJ48_23030	COG4638	Rieske (2fe-2S)
IUJ48_23035	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IUJ48_23055	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
IUJ48_23060	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_23085	COG0463	Glycosyl transferase, family 2
IUJ48_23085	COG1216	Glycosyl transferase, family 2
IUJ48_23100	COG0800	Aldolase
IUJ48_23110	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IUJ48_23150	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IUJ48_23155	COG1566	PFAM secretion protein HlyD family protein
IUJ48_23165	COG0577	efflux transmembrane transporter activity
IUJ48_23165	COG1136	(ABC) transporter
IUJ48_23195	COG1136	(ABC) transporter
IUJ48_23195	COG0577	efflux transmembrane transporter activity
IUJ48_23215	COG0583	DNA-binding transcription factor activity
IUJ48_23220	COG1538	Outer membrane efflux protein
IUJ48_23225	COG1136	(ABC) transporter
IUJ48_23225	COG0577	efflux transmembrane transporter activity
IUJ48_23230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IUJ48_23245	COG0259	pyridoxamine-phosphate oxidase activity
IUJ48_23255	COG0579	oxidoreductase
IUJ48_23265	COG0583	DNA-binding transcription factor activity
IUJ48_23275	COG2175	clavaminate synthase activity
IUJ48_23285	COG1304	FMN binding
IUJ48_23295	COG0179	Fumarylacetoacetate (FAA) hydrolase
IUJ48_23300	COG0583	DNA-binding transcription factor activity
IUJ48_23305	COG1960	acyl-CoA dehydrogenase activity
IUJ48_23315	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IUJ48_23320	COG0531	amino acid
IUJ48_23335	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_23345	COG0114	fumarate hydratase activity
IUJ48_23350	COG0802	atpase or kinase
IUJ48_23355	COG0860	N-Acetylmuramoyl-L-alanine amidase
IUJ48_23365	COG0586	Pfam SNARE associated Golgi protein
IUJ48_23370	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IUJ48_23375	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IUJ48_23385	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IUJ48_23400	COG0617	tRNA 3'-terminal CCA addition
IUJ48_23410	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IUJ48_23415	COG2301	Belongs to the HpcH HpaI aldolase family
IUJ48_23425	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
IUJ48_23435	COG1024	Enoyl-CoA hydratase
IUJ48_23445	COG1960	acyl-CoA dehydrogenase activity
IUJ48_23455	COG0183	Belongs to the thiolase family
IUJ48_23460	COG0318	PFAM AMP-dependent synthetase and ligase
IUJ48_23470	COG2070	2-Nitropropane dioxygenase
IUJ48_23485	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_23490	COG2030	dehydratase
IUJ48_23495	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IUJ48_23515	COG1024	Enoyl-CoA hydratase
IUJ48_23520	COG0752	glycyl-tRNA synthetase alpha subunit
IUJ48_23525	COG0751	glycine-tRNA ligase activity
IUJ48_23530	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IUJ48_23535	COG0204	Acyl-transferase
IUJ48_23555	COG0242	peptide deformylase activity
IUJ48_23560	COG1960	acyl-CoA dehydrogenase activity
IUJ48_23565	COG0700	Nucleoside recognition
IUJ48_23570	COG0469	pyruvate kinase activity
IUJ48_23575	COG1929	Belongs to the glycerate kinase type-1 family
IUJ48_23580	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IUJ48_23585	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IUJ48_23595	COG3178	'Phosphotransferase
IUJ48_23610	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IUJ48_23625	COG2154	pterin-4-alpha-carbinolamine dehydratase
IUJ48_23660	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_23675	COG2982	Protein involved in outer membrane biogenesis
IUJ48_23680	COG1368	sulfuric ester hydrolase activity
IUJ48_23685	COG2818	Glycosylase
IUJ48_23710	COG0735	belongs to the Fur family
IUJ48_23720	COG0583	DNA-binding transcription factor activity
IUJ48_23725	COG0840	transmembrane signaling receptor activity
IUJ48_23745	COG3712	iron ion homeostasis
IUJ48_23750	COG1595	DNA-templated transcription, initiation
IUJ48_23765	COG2011	ABC-type metal ion transport system permease component
IUJ48_23770	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IUJ48_23775	COG1501	Belongs to the glycosyl hydrolase 31 family
IUJ48_23780	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
IUJ48_23780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IUJ48_23785	COG0483	inositol monophosphate 1-phosphatase activity
IUJ48_23790	COG0318	PFAM AMP-dependent synthetase and ligase
IUJ48_23795	COG1473	amidohydrolase
IUJ48_23800	COG0583	DNA-binding transcription factor activity
IUJ48_23805	COG2855	membrane
IUJ48_23815	COG2239	Acts as a magnesium transporter
IUJ48_23830	COG1522	sequence-specific DNA binding
IUJ48_23835	COG0300	oxidoreductase activity
IUJ48_23845	COG0028	Belongs to the TPP enzyme family
IUJ48_23865	COG0653	protein targeting
IUJ48_23870	COG0739	heme binding
IUJ48_23880	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
IUJ48_23885	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IUJ48_23895	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IUJ48_23900	COG1181	Belongs to the D-alanine--D-alanine ligase family
IUJ48_23905	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IUJ48_23910	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IUJ48_23920	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IUJ48_23925	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IUJ48_23930	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IUJ48_23940	COG3116	cell division
IUJ48_23945	COG0275	rRNA processing
IUJ48_23950	COG2001	Belongs to the MraZ family
IUJ48_23960	COG0488	(ABC) transporter
IUJ48_23965	COG0418	dihydroorotase activity
IUJ48_23970	COG1473	amidohydrolase
IUJ48_23980	COG0583	DNA-binding transcription factor activity
IUJ48_24020	COG1522	sequence-specific DNA binding
IUJ48_24030	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IUJ48_24035	COG4654	Cytochrome c, class I
IUJ48_24040	COG0129	dihydroxy-acid dehydratase activity
IUJ48_24080	COG0405	Gamma-glutamyltransferase
IUJ48_24085	COG2084	Dehydrogenase
IUJ48_24100	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IUJ48_24130	COG0442	prolyl-tRNA aminoacylation
IUJ48_24135	COG0824	Thioesterase
IUJ48_24140	COG0811	peptide transport
IUJ48_24145	COG0848	biopolymer transport protein
IUJ48_24155	COG0823	Involved in the tonB-independent uptake of proteins
IUJ48_24170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IUJ48_24175	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
IUJ48_24190	COG1522	sequence-specific DNA binding
IUJ48_24200	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IUJ48_24215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IUJ48_24220	COG0697	spore germination
IUJ48_24230	COG1346	cytolysis
IUJ48_24240	COG0583	DNA-binding transcription factor activity
IUJ48_24250	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IUJ48_24270	COG0559	Belongs to the binding-protein-dependent transport system permease family
IUJ48_24290	COG0583	DNA-binding transcription factor activity
IUJ48_24305	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IUJ48_24310	COG0463	Glycosyl transferase, family 2
IUJ48_24320	COG0786	glutamate:sodium symporter activity
IUJ48_24335	COG1671	Belongs to the UPF0178 family
IUJ48_24350	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IUJ48_24355	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IUJ48_24365	COG0328	RNA-DNA hybrid ribonuclease activity
IUJ48_24370	COG2226	methyltransferase
IUJ48_24375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IUJ48_24380	COG0741	lytic transglycosylase activity
IUJ48_24380	COG1388	LysM domain
IUJ48_24420	COG1366	Belongs to the anti-sigma-factor antagonist family
IUJ48_24425	COG2172	sigma factor antagonist activity
IUJ48_24430	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IUJ48_24440	COG2208	phosphoserine phosphatase activity
IUJ48_24440	COG2770	Histidine kinase
IUJ48_24460	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_24470	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IUJ48_24480	COG1942	4-Oxalocrotonate Tautomerase
IUJ48_24485	COG0583	DNA-binding transcription factor activity
IUJ48_24495	COG2719	SpoVR family
IUJ48_24500	COG2718	Belongs to the UPF0229 family
IUJ48_24505	COG2766	serine protein kinase
IUJ48_24520	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IUJ48_24520	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IUJ48_24535	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IUJ48_24540	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IUJ48_24555	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IUJ48_24570	COG0316	Belongs to the HesB IscA family
IUJ48_24580	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IUJ48_24585	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IUJ48_24590	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IUJ48_24605	COG4177	L-phenylalanine transmembrane transporter activity
IUJ48_24620	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IUJ48_24625	COG0312	modulator of DNA gyrase
IUJ48_24630	COG3028	Belongs to the UPF0307 family
IUJ48_24645	COG1116	anion transmembrane transporter activity
IUJ48_24650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IUJ48_24655	COG1335	isochorismatase
IUJ48_24660	COG0045	succinate-CoA ligase (ADP-forming) activity
IUJ48_24660	COG1042	CoA-binding domain protein
IUJ48_24660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IUJ48_24665	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IUJ48_24680	COG0583	DNA-binding transcription factor activity
IUJ48_24690	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_24695	COG1522	sequence-specific DNA binding
IUJ48_24730	COG1696	Membrane protein involved in D-alanine export
IUJ48_24755	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
IUJ48_24755	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
IUJ48_24765	COG2264	protein methyltransferase activity
IUJ48_24770	COG0439	Biotin carboxylase
IUJ48_24775	COG0511	ligase activity, forming carbon-carbon bonds
IUJ48_24780	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
IUJ48_24785	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IUJ48_24790	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IUJ48_24795	COG3150	esterase
IUJ48_24800	COG0557	exoribonuclease II activity
IUJ48_24820	COG1175	transmembrane transport
IUJ48_24825	COG3842	ATPase activity
IUJ48_24835	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IUJ48_24840	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IUJ48_24850	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IUJ48_24855	COG1126	abc transporter atp-binding protein
IUJ48_24865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ48_24870	COG0436	Aminotransferase
IUJ48_24875	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IUJ48_24900	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IUJ48_24905	COG1678	Uncharacterized ACR, COG1678
IUJ48_24920	COG0352	thiamine-phosphate diphosphorylase activity
IUJ48_24925	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IUJ48_24930	COG0741	lytic transglycosylase activity
IUJ48_24940	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_24945	COG1335	isochorismatase
IUJ48_24950	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IUJ48_24955	COG4638	Rieske (2fe-2S)
IUJ48_24995	COG1024	Enoyl-CoA hydratase
IUJ48_25000	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_25035	COG0410	ABC transporter
IUJ48_25070	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IUJ48_25090	COG3842	ATPase activity
IUJ48_25095	COG1175	transmembrane transport
IUJ48_25100	COG3833	ABC-type maltose transport systems, permease component
IUJ48_25115	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
IUJ48_25120	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IUJ48_25150	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
IUJ48_25155	COG0237	dephospho-CoA kinase activity
IUJ48_25175	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IUJ48_25180	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IUJ48_25190	COG0477	Major facilitator Superfamily
IUJ48_25225	COG1605	Chorismate mutase
IUJ48_25225	COG0077	Prephenate dehydratase
IUJ48_25235	COG2081	HI0933 family
IUJ48_25240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IUJ48_25255	COG4177	L-phenylalanine transmembrane transporter activity
IUJ48_25260	COG1129	ABC transporter
IUJ48_25285	COG1126	abc transporter atp-binding protein
IUJ48_25290	COG0765	amino acid transport
IUJ48_25295	COG4597	amino acid ABC transporter
IUJ48_25300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ48_25305	COG2884	Cell division ATP-binding protein ftsE
IUJ48_25310	COG2177	Part of the ABC transporter FtsEX involved in
IUJ48_25335	COG1194	a g-specific adenine glycosylase
IUJ48_25350	COG0246	Mannitol dehydrogenase
IUJ48_25355	COG4948	Mandelate Racemase Muconate Lactonizing
IUJ48_25360	COG1126	abc transporter atp-binding protein
IUJ48_25365	COG0765	amino acid transport
IUJ48_25375	COG1063	alcohol dehydrogenase
IUJ48_25390	COG2186	Transcriptional regulator
IUJ48_25400	COG4771	TonB-dependent receptor
IUJ48_25405	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IUJ48_25410	COG2022	thiamine diphosphate biosynthetic process
IUJ48_25415	COG0351	phosphomethylpyrimidine kinase
IUJ48_25420	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IUJ48_25430	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
IUJ48_25440	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IUJ48_25455	COG2226	methyltransferase
IUJ48_25460	COG0745	RESPONSE REGULATOR receiver
IUJ48_25485	COG2132	Multicopper oxidase
IUJ48_25500	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IUJ48_25510	COG0583	DNA-binding transcription factor activity
IUJ48_25520	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
IUJ48_25525	COG1984	allophanate hydrolase subunit 2
IUJ48_25535	COG1802	Transcriptional regulator
IUJ48_25540	COG2860	membrane
IUJ48_25550	COG2223	nitrite transmembrane transporter activity
IUJ48_25555	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IUJ48_25555	COG2813	Specifically methylates the guanine in position
IUJ48_25560	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IUJ48_25565	COG2188	Transcriptional regulator
IUJ48_25570	COG2721	sulfolactate sulfo-lyase activity
IUJ48_25575	COG2721	sulfolactate sulfo-lyase activity
IUJ48_25585	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IUJ48_25590	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
IUJ48_25620	COG2918	glutathione biosynthetic process
IUJ48_25630	COG2988	succinylglutamate desuccinylase activity
IUJ48_25640	COG0583	DNA-binding transcription factor activity
IUJ48_25650	COG1802	Transcriptional regulator
IUJ48_25665	COG1129	ABC transporter
IUJ48_25685	COG0179	Fumarylacetoacetate (FAA) hydrolase
IUJ48_25700	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IUJ48_25705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IUJ48_25710	COG1595	DNA-templated transcription, initiation
IUJ48_25720	COG0583	DNA-binding transcription factor activity
IUJ48_25725	COG1764	response to oxidative stress
IUJ48_25740	COG2814	Major facilitator Superfamily
IUJ48_25755	COG1250	3-hydroxyacyl-CoA dehydrogenase
IUJ48_25770	COG1309	transcriptional regulator
IUJ48_25780	COG1024	Enoyl-CoA hydratase
IUJ48_25785	COG1024	Enoyl-CoA hydratase
IUJ48_25790	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IUJ48_25800	COG0747	negative chemotaxis
IUJ48_25805	COG0583	DNA-binding transcription factor activity
IUJ48_25815	COG2988	succinylglutamate desuccinylase activity
IUJ48_25820	COG0747	negative chemotaxis
IUJ48_25825	COG0601	transmembrane transport
IUJ48_25835	COG0444	Belongs to the ABC transporter superfamily
IUJ48_25840	COG4608	Belongs to the ABC transporter superfamily
IUJ48_25850	COG2195	Cleaves the N-terminal amino acid of tripeptides
IUJ48_25860	COG2171	N-acyltransferase activity
IUJ48_25870	COG4221	oxidoreductase activity
IUJ48_25875	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IUJ48_25890	COG0210	DNA helicase
IUJ48_25895	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IUJ48_25900	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IUJ48_25910	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IUJ48_25920	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IUJ48_25925	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IUJ48_25930	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IUJ48_25945	COG0356	it plays a direct role in the translocation of protons across the membrane
IUJ48_25960	COG1024	Enoyl-CoA hydratase
IUJ48_25965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IUJ48_25975	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IUJ48_25990	COG0583	DNA-binding transcription factor activity
IUJ48_25995	COG3473	Maleate cis-trans isomerase
IUJ48_26020	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IUJ48_26035	COG0559	Belongs to the binding-protein-dependent transport system permease family
IUJ48_26040	COG0559	Belongs to the binding-protein-dependent transport system permease family
IUJ48_26070	COG0037	tRNA processing
IUJ48_26080	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IUJ48_26085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IUJ48_26095	COG2967	ApaG domain
IUJ48_26100	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IUJ48_26105	COG0546	phosphoglycolate phosphatase activity
IUJ48_26115	COG0512	Glutamine amidotransferase of anthranilate synthase
IUJ48_26120	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IUJ48_26125	COG0134	indole-3-glycerol-phosphate synthase activity
IUJ48_26130	COG3284	Transcriptional regulator
IUJ48_26135	COG1012	belongs to the aldehyde dehydrogenase family
IUJ48_26170	COG0709	Synthesizes selenophosphate from selenide and ATP
IUJ48_26175	COG1305	Transglutaminase-like
IUJ48_26180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IUJ48_26185	COG1216	Glycosyl transferase, family 2
IUJ48_26195	COG3276	selenocysteine insertion sequence binding
IUJ48_26210	COG2864	formate dehydrogenase
IUJ48_26215	COG0437	4 iron, 4 sulfur cluster binding
IUJ48_26230	COG1607	acyl-coa hydrolase
IUJ48_26255	COG3064	Membrane
IUJ48_26260	COG3585	molybdate ion transport
IUJ48_26265	COG1116	anion transmembrane transporter activity
IUJ48_26270	COG1464	Belongs to the NlpA lipoprotein family
IUJ48_26275	COG2011	ABC-type metal ion transport system permease component
IUJ48_26290	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IUJ48_26295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IUJ48_26300	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IUJ48_26305	COG0431	NADPH-dependent FMN reductase
IUJ48_26310	COG1464	Belongs to the NlpA lipoprotein family
IUJ48_26335	COG0747	negative chemotaxis
IUJ48_26345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IUJ48_26375	COG3069	C4-dicarboxylate transmembrane transporter activity
IUJ48_26385	COG1802	Transcriptional regulator
IUJ48_26445	COG3188	usher protein
IUJ48_26460	COG2814	Major facilitator Superfamily
IUJ48_26465	COG0840	transmembrane signaling receptor activity
IUJ48_26480	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IUJ48_26485	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IUJ48_26495	COG2188	Transcriptional regulator
IUJ48_26510	COG0737	Belongs to the 5'-nucleotidase family
IUJ48_26560	COG0463	Glycosyl transferase, family 2
IUJ48_26565	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IUJ48_26575	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IUJ48_26585	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IUJ48_26590	COG0218	Necessary for normal cell division and for the maintenance of normal septation
IUJ48_26595	COG2423	ornithine cyclodeaminase activity
IUJ48_26605	COG0583	DNA-binding transcription factor activity
IUJ48_26610	COG2814	Major facilitator Superfamily
IUJ48_26615	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IUJ48_26620	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
IUJ48_26645	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IUJ48_26660	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IUJ48_26665	COG1120	ATPase activity
IUJ48_26670	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IUJ48_26675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IUJ48_26680	COG4592	Periplasmic binding protein
IUJ48_26685	COG4774	siderophore transport
IUJ48_26700	COG2814	Major facilitator Superfamily
IUJ48_26710	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IUJ48_26730	COG0438	transferase activity, transferring glycosyl groups
IUJ48_26740	COG2814	Major facilitator Superfamily
IUJ48_26745	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IUJ48_26765	COG1999	signal sequence binding
IUJ48_26775	COG1612	heme a metabolic process
IUJ48_26795	COG1845	cytochrome c oxidase, subunit III
IUJ48_26805	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IUJ48_26825	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IUJ48_26850	COG0070	glutamate synthase
IUJ48_26850	COG0069	glutamate synthase activity
IUJ48_26850	COG0067	glutamate synthase
IUJ48_26865	COG1984	allophanate hydrolase subunit 2
IUJ48_26880	COG0511	ligase activity, forming carbon-carbon bonds
IUJ48_26885	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
IUJ48_26890	COG0583	DNA-binding transcription factor activity
IUJ48_26905	COG0477	Major facilitator Superfamily
IUJ48_26915	COG2070	2-Nitropropane dioxygenase
IUJ48_26920	COG1127	ABC transporter
IUJ48_26925	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IUJ48_26930	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IUJ48_26935	COG2853	Lipoprotein
IUJ48_26945	COG1131	(ABC) transporter
IUJ48_26950	COG0842	Transport permease protein
IUJ48_26960	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IUJ48_26965	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IUJ48_26970	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IUJ48_26975	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IUJ48_26980	COG0131	Imidazoleglycerol-phosphate dehydratase
IUJ48_26985	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IUJ48_26990	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IUJ48_26995	COG0107	imidazoleglycerol-phosphate synthase activity
IUJ48_27000	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IUJ48_27005	COG0140	phosphoribosyl-ATP diphosphatase activity
IUJ48_27010	COG0537	adenosine 5'-monophosphoramidase activity
IUJ48_27015	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IUJ48_27035	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IUJ48_27040	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IUJ48_27045	COG1970	mechanosensitive ion channel activity
IUJ48_27050	COG0723	plastoquinol--plastocyanin reductase activity
IUJ48_27055	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IUJ48_27060	COG2857	Cytochrome c1
IUJ48_27065	COG0625	glutathione transferase activity
IUJ48_27070	COG2969	positive regulation of protein catabolic process
IUJ48_27100	COG0583	DNA-binding transcription factor activity
IUJ48_27110	COG1104	cysteine desulfurase activity
IUJ48_27120	COG2207	Transcriptional regulator
IUJ48_27120	COG3708	Transcriptional regulator
IUJ48_27130	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IUJ48_27135	COG0747	negative chemotaxis
IUJ48_27140	COG0601	transmembrane transport
IUJ48_27145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IUJ48_27155	COG1228	amidohydrolase
IUJ48_27160	COG5339	Protein conserved in bacteria
IUJ48_27165	COG5339	Protein conserved in bacteria
IUJ48_27170	COG0513	Belongs to the DEAD box helicase family
IUJ48_27175	COG1280	lysine exporter protein (LysE YggA)
IUJ48_27180	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IUJ48_27200	COG0583	DNA-binding transcription factor activity
IUJ48_27220	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
IUJ48_27235	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IUJ48_27245	COG1609	Transcriptional regulator
IUJ48_27250	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IUJ48_27260	COG1653	transport
IUJ48_27265	COG1175	transmembrane transport
IUJ48_27270	COG0395	ABC-type sugar transport system, permease component
IUJ48_27285	COG0018	arginyl-trna synthetase
IUJ48_27295	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IUJ48_27320	COG1280	lysine exporter protein (LysE YggA)
IUJ48_27335	COG1742	UPF0060 membrane protein
IUJ48_27345	COG1473	amidohydrolase
IUJ48_27350	COG1960	acyl-CoA dehydrogenase activity
IUJ48_27355	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
IUJ48_27360	COG0183	Belongs to the thiolase family
IUJ48_27365	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IUJ48_27415	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_27430	COG0318	PFAM AMP-dependent synthetase and ligase
IUJ48_27435	COG1595	DNA-templated transcription, initiation
IUJ48_27450	COG2814	Major facilitator Superfamily
IUJ48_27455	COG2186	Transcriptional regulator
IUJ48_27485	COG3339	Conserved Protein
IUJ48_27495	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
IUJ48_27505	COG2814	Major facilitator Superfamily
IUJ48_27530	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IUJ48_27535	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_27540	COG3422	double-strand break repair
IUJ48_27545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ48_27550	COG0765	amino acid transport
IUJ48_27555	COG0765	amino acid transport
IUJ48_27575	COG2358	TRAP transporter, solute receptor (TAXI family
IUJ48_27585	COG2922	Belongs to the Smg family
IUJ48_27590	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IUJ48_27615	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IUJ48_27620	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_27625	COG0028	Belongs to the TPP enzyme family
IUJ48_27630	COG1522	sequence-specific DNA binding
IUJ48_27635	COG3781	membrane
IUJ48_27650	COG2814	Major facilitator Superfamily
IUJ48_27665	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IUJ48_27680	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IUJ48_27690	COG1744	ABC transporter substrate-binding protein PnrA-like
IUJ48_27695	COG3845	ABC transporter
IUJ48_27700	COG4603	Belongs to the binding-protein-dependent transport system permease family
IUJ48_27710	COG0402	S-adenosylhomocysteine deaminase activity
IUJ48_27715	COG0251	oxidation-reduction process
IUJ48_27740	COG1177	transmembrane transport
IUJ48_27745	COG1176	ABC-type spermidine putrescine transport system, permease component I
IUJ48_27750	COG3842	ATPase activity
IUJ48_27760	COG1609	Transcriptional regulator
IUJ48_27815	COG1177	transmembrane transport
IUJ48_27820	COG1176	ABC-type spermidine putrescine transport system, permease component I
IUJ48_27825	COG3842	ATPase activity
IUJ48_27860	COG1126	abc transporter atp-binding protein
IUJ48_27865	COG0765	amino acid transport
IUJ48_27870	COG0765	amino acid transport
IUJ48_27875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ48_27880	COG0583	DNA-binding transcription factor activity
IUJ48_27890	COG1574	metal-dependent hydrolase with the TIM-barrel fold
IUJ48_27915	COG0583	DNA-binding transcription factor activity
IUJ48_27920	COG0583	DNA-binding transcription factor activity
IUJ48_27925	COG2814	Major facilitator Superfamily
IUJ48_27935	COG0592	DNA-directed DNA polymerase activity
IUJ48_27940	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IUJ48_27945	COG0230	Belongs to the bacterial ribosomal protein bL34 family
IUJ48_27950	COG0594	ribonuclease P activity
IUJ48_27955	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
IUJ48_27965	COG0753	catalase activity
IUJ48_27970	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IUJ48_27980	COG2175	clavaminate synthase activity
IUJ48_27985	COG1473	amidohydrolase
IUJ48_27990	COG4608	Belongs to the ABC transporter superfamily
IUJ48_27995	COG0444	Belongs to the ABC transporter superfamily
IUJ48_28000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IUJ48_28005	COG0601	transmembrane transport
IUJ48_28015	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IUJ48_28030	COG0038	chloride channel
IUJ48_28060	COG0436	Aminotransferase
IUJ48_28065	COG3180	Ammonia monooxygenase
IUJ48_28070	COG1278	Cold shock
IUJ48_28075	COG0445	tRNA wobble uridine modification
IUJ48_28080	COG0357	Ribosomal RNA small subunit methyltransferase G
IUJ48_28085	COG1192	Involved in chromosome partitioning
IUJ48_28095	COG1475	DNA binding
IUJ48_28100	COG0252	asparaginase activity
IUJ48_28105	COG0583	DNA-binding transcription factor activity
IUJ48_28130	COG1349	DNA-binding transcription factor activity
IUJ48_28140	COG3842	ATPase activity
IUJ48_28145	COG1840	ABC-type Fe3 transport system, periplasmic component
IUJ48_28185	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IUJ48_28195	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IUJ48_28205	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IUJ48_28210	COG0081	regulation of translation
IUJ48_28215	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IUJ48_28220	COG0222	ribosome binding
IUJ48_28225	COG0085	RNA polymerase activity
IUJ48_28230	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IUJ48_28245	COG5002	protein histidine kinase activity
IUJ48_28260	COG0745	RESPONSE REGULATOR receiver
IUJ48_28265	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IUJ48_28270	COG0049	tRNA binding
IUJ48_28275	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IUJ48_28280	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IUJ48_28285	COG0051	transcription antitermination factor activity, RNA binding
IUJ48_28290	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IUJ48_28300	COG0089	rRNA binding
IUJ48_28305	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IUJ48_28310	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IUJ48_28315	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IUJ48_28320	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IUJ48_28325	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IUJ48_28330	COG0255	Belongs to the universal ribosomal protein uL29 family
IUJ48_28335	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IUJ48_28375	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IUJ48_28390	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IUJ48_28390	COG2169	Transcriptional regulator
IUJ48_28405	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IUJ48_28410	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IUJ48_28415	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IUJ48_28420	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IUJ48_28425	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IUJ48_28430	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IUJ48_28435	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IUJ48_28440	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IUJ48_28445	COG1841	ribosomal large subunit assembly
IUJ48_28450	COG0200	Binds to the 23S rRNA
IUJ48_28455	COG0201	protein transport
IUJ48_28460	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IUJ48_28465	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IUJ48_28470	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IUJ48_28475	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IUJ48_28480	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IUJ48_28485	COG0202	RNA polymerase activity
IUJ48_28490	COG0203	ribosomal protein L17
IUJ48_28500	COG1324	tolerance protein
IUJ48_28505	COG4232	protein-disulfide reductase activity
IUJ48_28520	COG0218	Necessary for normal cell division and for the maintenance of normal septation
IUJ48_28530	COG1333	cytochrome c biogenesis protein
IUJ48_28535	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IUJ48_28540	COG0019	diaminopimelate decarboxylase activity
IUJ48_28550	COG1965	Belongs to the frataxin family
IUJ48_28560	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IUJ48_28565	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IUJ48_28570	COG0232	Belongs to the dGTPase family. Type 2 subfamily
IUJ48_28575	COG0625	glutathione transferase activity
IUJ48_28585	COG2814	Major facilitator Superfamily
IUJ48_28595	COG4106	trans-aconitate 2-methyltransferase activity
IUJ48_28635	COG2186	Transcriptional regulator
IUJ48_28650	COG1422	Protein of unknown function (DUF1090)
IUJ48_28660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IUJ48_28665	COG1956	GAF domain-containing protein
IUJ48_28670	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IUJ48_28685	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IUJ48_28710	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IUJ48_28715	COG3568	Endonuclease Exonuclease Phosphatase
IUJ48_28740	COG0697	spore germination
IUJ48_28745	COG2814	Major facilitator Superfamily
IUJ48_28760	COG0367	asparagine synthase
IUJ48_28775	COG2226	methyltransferase
IUJ48_28805	COG0175	sulfate reduction
IUJ48_28820	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IUJ48_28830	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IUJ48_28840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IUJ48_28855	COG0367	asparagine synthase
IUJ48_28890	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IUJ48_28915	COG0859	PFAM glycosyl transferase family 9
IUJ48_28930	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IUJ48_28940	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IUJ48_28965	COG1686	Belongs to the peptidase S11 family
IUJ48_28975	COG2921	Belongs to the UPF0250 family
IUJ48_28980	COG0321	lipoyl(octanoyl) transferase activity
IUJ48_28995	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IUJ48_29000	COG2096	Adenosyltransferase
IUJ48_29010	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IUJ48_29015	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IUJ48_29025	COG0523	cobalamin synthesis protein
IUJ48_29030	COG0735	belongs to the Fur family
IUJ48_29045	COG0803	Belongs to the bacterial solute-binding protein 9 family
IUJ48_29055	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
IUJ48_29060	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IUJ48_29070	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IUJ48_29085	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IUJ48_29090	COG0154	amidase activity
IUJ48_29095	COG0477	Major facilitator Superfamily
IUJ48_29105	COG0583	DNA-binding transcription factor activity
IUJ48_29120	COG0066	3-isopropylmalate dehydratase activity
IUJ48_29135	COG0438	transferase activity, transferring glycosyl groups
IUJ48_29140	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IUJ48_29145	COG1950	PFAM Membrane protein of
IUJ48_29165	COG1305	Transglutaminase-like
IUJ48_29175	COG2308	Evidence 4 Homologs of previously reported genes of
IUJ48_29180	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IUJ48_29190	COG0617	tRNA 3'-terminal CCA addition
IUJ48_29200	COG0513	Belongs to the DEAD box helicase family
IUJ48_29205	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IUJ48_29275	COG0443	Heat shock 70 kDa protein
IUJ48_29285	COG0352	thiamine-phosphate diphosphorylase activity
IUJ48_29285	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IUJ48_29285	COG0351	phosphomethylpyrimidine kinase
IUJ48_29290	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_29310	COG3189	MarR family transcriptional regulator
IUJ48_29340	COG0640	Transcriptional regulator
IUJ48_29400	COG1846	Transcriptional regulator
IUJ48_29405	COG1764	response to oxidative stress
IUJ48_29430	COG0583	DNA-binding transcription factor activity
IUJ48_29440	COG0583	DNA-binding transcription factor activity
IUJ48_29450	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IUJ48_29455	COG0708	Exodeoxyribonuclease III
IUJ48_29460	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IUJ48_29475	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IUJ48_29480	COG0154	amidase activity
IUJ48_29485	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IUJ48_29490	COG1077	Cell shape determining protein MreB Mrl
IUJ48_29495	COG1792	Involved in formation and maintenance of cell shape
IUJ48_29505	COG0768	penicillin binding
IUJ48_29510	COG0772	Belongs to the SEDS family
IUJ48_29515	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
IUJ48_29520	COG0471	metal ion transport
IUJ48_29525	COG1309	transcriptional regulator
IUJ48_29535	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IUJ48_29540	COG1464	Belongs to the NlpA lipoprotein family
IUJ48_29545	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IUJ48_29555	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
IUJ48_29560	COG0792	nuclease activity
IUJ48_29570	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IUJ48_29580	COG1660	Displays ATPase and GTPase activities
IUJ48_29595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IUJ48_29600	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IUJ48_29610	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IUJ48_29615	COG1137	ATPase activity
IUJ48_29630	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IUJ48_29640	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IUJ48_29655	COG1294	oxidase, subunit
IUJ48_29665	COG4988	ABC transporter
IUJ48_29670	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IUJ48_29675	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IUJ48_29690	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IUJ48_29695	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IUJ48_29700	COG1238	metal cluster binding
IUJ48_29715	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_29720	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IUJ48_29725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IUJ48_29730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ48_29745	COG0758	DNA mediated transformation
IUJ48_29750	COG0242	peptide deformylase activity
IUJ48_29755	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IUJ48_29765	COG0546	phosphoglycolate phosphatase activity
IUJ48_29785	COG1733	regulation of RNA biosynthetic process
IUJ48_29795	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IUJ48_29800	COG1280	lysine exporter protein (LysE YggA)
IUJ48_29805	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IUJ48_29805	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IUJ48_29815	COG5000	phosphorelay sensor kinase activity
IUJ48_29820	COG2204	response regulator
IUJ48_29825	COG0569	domain protein
IUJ48_29830	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IUJ48_29835	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
IUJ48_29840	COG2226	methyltransferase
IUJ48_29845	COG1040	competence protein
IUJ48_29855	COG3181	Tripartite tricarboxylate transporter family receptor
IUJ48_29860	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
IUJ48_29865	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
IUJ48_29870	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IUJ48_29880	COG0588	phosphoglycerate mutase activity
IUJ48_29885	COG4942	peptidase
IUJ48_29890	COG0793	Belongs to the peptidase S41A family
IUJ48_29895	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IUJ48_29900	COG5001	Diguanylate cyclase
IUJ48_29900	COG5002	protein histidine kinase activity
IUJ48_29900	COG3447	MASE1 domain protein
IUJ48_29905	COG2186	Transcriptional regulator
IUJ48_29915	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IUJ48_29920	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IUJ48_29935	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IUJ48_29940	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IUJ48_29945	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IUJ48_29950	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IUJ48_29955	COG0142	geranyltranstransferase activity
IUJ48_29965	COG0489	protein tyrosine kinase activity
IUJ48_30020	COG0551	DNA topoisomerase type I activity
IUJ48_30020	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IUJ48_30070	COG2433	Pfam Transposase IS66
IUJ48_30095	COG0659	secondary active sulfate transmembrane transporter activity
IUJ48_30100	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IUJ48_30115	COG0459	protein refolding
IUJ48_30125	COG1185	polyribonucleotide nucleotidyltransferase activity
IUJ48_30140	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IUJ48_30145	COG0659	secondary active sulfate transmembrane transporter activity
IUJ48_30150	COG0589	response to stress
IUJ48_30165	COG0438	transferase activity, transferring glycosyl groups
IUJ48_30175	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IUJ48_30180	COG0785	Cytochrome C biogenesis protein
IUJ48_30215	COG3220	belongs to the UPF0276 family
IUJ48_30240	COG0789	Transcriptional regulator
IUJ48_30250	COG2608	mercury ion transmembrane transporter activity
IUJ48_30255	COG2608	mercury ion transmembrane transporter activity
IUJ48_30260	COG0789	Transcriptional regulator
IUJ48_30275	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IUJ48_30280	COG4654	Cytochrome c, class I
IUJ48_30300	COG4191	Histidine kinase
IUJ48_30325	COG0431	NADPH-dependent FMN reductase
IUJ48_30355	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IUJ48_30360	COG0573	inorganic phosphate transmembrane transporter activity
IUJ48_30365	COG0581	inorganic phosphate transmembrane transporter activity
IUJ48_30380	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IUJ48_30395	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IUJ48_30400	COG3593	DNA synthesis involved in DNA repair
IUJ48_30460	COG3133	Outer membrane lipoprotein
IUJ48_30500	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IUJ48_30525	COG2948	multi-organism process
IUJ48_30560	COG3451	type IV secretory pathway VirB4
IUJ48_30680	COG0235	Class ii aldolase
IUJ48_30685	COG3622	Belongs to the hyi family
IUJ48_30690	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IUJ48_30695	COG2084	Dehydrogenase
IUJ48_30700	COG3395	kinase activity
IUJ48_30705	COG2186	Transcriptional regulator
IUJ48_30710	COG0583	DNA-binding transcription factor activity
IUJ48_30730	COG3622	Belongs to the hyi family
IUJ48_30750	COG1522	sequence-specific DNA binding
IUJ48_30755	COG1280	lysine exporter protein (LysE YggA)
IUJ48_30770	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IUJ48_30775	COG2890	protein-(glutamine-N5) methyltransferase activity
IUJ48_30780	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IUJ48_30795	COG1464	Belongs to the NlpA lipoprotein family
IUJ48_30815	COG0318	PFAM AMP-dependent synthetase and ligase
IUJ48_30840	COG0477	Major facilitator Superfamily
IUJ48_30845	COG0583	DNA-binding transcription factor activity
IUJ48_30855	COG0583	DNA-binding transcription factor activity
IUJ48_30870	COG0625	glutathione transferase activity
IUJ48_30875	COG1053	succinate dehydrogenase
IUJ48_30885	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_30905	COG0559	Belongs to the binding-protein-dependent transport system permease family
IUJ48_30915	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_30920	COG1802	Transcriptional regulator
IUJ48_30925	COG0288	reversible hydration of carbon dioxide
IUJ48_30945	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IUJ48_30955	COG4829	muconolactone delta-isomerase
IUJ48_30960	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IUJ48_30970	COG1414	Transcriptional regulator
IUJ48_30975	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_30980	COG2031	fatty acid transporter
IUJ48_30985	COG1250	3-hydroxyacyl-CoA dehydrogenase
IUJ48_30990	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IUJ48_30995	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IUJ48_31000	COG2200	EAL domain
IUJ48_31015	COG0583	DNA-binding transcription factor activity
IUJ48_31020	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IUJ48_31030	COG0129	dihydroxy-acid dehydratase activity
IUJ48_31035	COG0583	DNA-binding transcription factor activity
IUJ48_31040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IUJ48_31045	COG0508	dehydrogenase complex catalyzes the overall conversion of
IUJ48_31055	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IUJ48_31060	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_31065	COG0410	ABC transporter
IUJ48_31090	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IUJ48_31100	COG2186	Transcriptional regulator
IUJ48_31110	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
IUJ48_31130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IUJ48_31135	COG0583	DNA-binding transcription factor activity
IUJ48_31140	COG0628	permease
IUJ48_31160	COG1176	ABC-type spermidine putrescine transport system, permease component I
IUJ48_31165	COG3842	ATPase activity
IUJ48_31175	COG0277	FAD linked oxidase domain protein
IUJ48_31190	COG0477	Major facilitator Superfamily
IUJ48_31205	COG1695	Transcriptional regulator
IUJ48_31215	COG0583	DNA-binding transcription factor activity
IUJ48_31235	COG0784	Response regulator, receiver
IUJ48_31235	COG2198	Histidine kinase
IUJ48_31235	COG5002	protein histidine kinase activity
IUJ48_31345	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ48_31355	COG3246	L-lysine catabolic process to acetate
IUJ48_31360	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IUJ48_31365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ48_31380	COG2233	PERMEase
IUJ48_31390	COG0326	Molecular chaperone. Has ATPase activity
IUJ48_31395	COG2814	Major facilitator Superfamily
IUJ48_31400	COG4774	siderophore transport