locus-tag	class	description
Acfer_0001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
Acfer_0003	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
Acfer_0004	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
Acfer_0005	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
Acfer_0008	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Acfer_0010	ENOG4105EJ9	Membrane
Acfer_0011	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Acfer_0013	ENOG4105CMU	LysR family (Transcriptional regulator
Acfer_0014	ENOG4105C6K	Malic enzyme
Acfer_0016	ENOG4105C32	Amino acid ABC transporter (Permease)
Acfer_0017	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
Acfer_0018	ENOG4105C0Z	ABC transporter
Acfer_0019	ENOG4108IV0	ABC, transporter
Acfer_0020	ENOG4105W87	Cbs domain
Acfer_0024	ENOG41061AI	Protein of unknown function (DUF2905)
Acfer_0028	ENOG4105CFC	Transporter
Acfer_0030	ENOG4105CH2	amidohydrolase
Acfer_0034	ENOG4105DY9	regulatoR
Acfer_0036	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
Acfer_0038	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
Acfer_0039	ENOG4108UUM	single-stranded DNA-binding protein
Acfer_0040	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
Acfer_0042	ENOG4105BZR	domain protein
Acfer_0043	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
Acfer_0044	ENOG4105CDU	Replicative dna helicase
Acfer_0045	ENOG4105C83	adenylosuccinate lyase
Acfer_0046	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
Acfer_0047	ENOG4105D6U	Sodium Glutamate Symporter
Acfer_0051	ENOG4105DUM	transcriptional regulator, lysR family
Acfer_0052	ENOG4105TMB	Formate nitrite transporter
Acfer_0057	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
Acfer_0061	ENOG4108UI1	Probably functions as a manganese efflux pump (By similarity)
Acfer_0062	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
Acfer_0063	ENOG4108UZ3	Transporter
Acfer_0066	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
Acfer_0068	ENOG4108JQ1	Dehydrogenase
Acfer_0071	ENOG4105EQX	glucarate dehydratase
Acfer_0072	ENOG4105C6Z	Gluconate
Acfer_0075	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
Acfer_0076	ENOG4105DQU	oxidoreductase, subunit beta
Acfer_0078	ENOG4105C01	Dihydroxy-acid dehydratase
Acfer_0080	ENOG4105CYC	Transferase
Acfer_0082	ENOG4105CTX	dehydratase
Acfer_0083	ENOG4105DFD	Na H antiporter
Acfer_0084	ENOG41090R7	Ferric uptake
Acfer_0085	ENOG4105FAV	ABC, transporter
Acfer_0086	ENOG4105FDK	ABC transporter
Acfer_0087	ENOG4105DSE	periplasmic solute binding protein
Acfer_0089	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Acfer_0090	ENOG4105EB3	Histidine kinase
Acfer_0093	ENOG4105KVH	Transcriptional regulator
Acfer_0096	ENOG4107QM5	aconitate hydratase
Acfer_0097	ENOG4105D4T	Citrate transporter
Acfer_0098	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Acfer_0099	ENOG4105DHQ	Histidine kinase
Acfer_0103	ENOG4105NBF	ammecr1 domain protein
Acfer_0108	ENOG4107SVV	electron transport complex, RnfABCDGE type, B subunit
Acfer_0109	ENOG4105DGN	Electron transport complex
Acfer_0110	ENOG4105DZB	Electron transport complex
Acfer_0111	ENOG4108UQQ	Electron transport complex
Acfer_0112	ENOG4105D6A	Electron transport complex
Acfer_0113	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
Acfer_0116	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Acfer_0117	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
Acfer_0118	ENOG4105CNI	cell division protein FtsW
Acfer_0119	ENOG4105CJN	penicillin-binding protein
Acfer_0120	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
Acfer_0125	ENOG4105BZU	Histidine kinase
Acfer_0131	ENOG4105CQB	FAD linked oxidase domain protein
Acfer_0133	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
Acfer_0134	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
Acfer_0136	ENOG4105CE4	GlcNAc 6-P deacetylase
Acfer_0137	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
Acfer_0140	ENOG4105C3G	gtp-binding protein
Acfer_0141	ENOG4107RVV	histidinol phosphate phosphatase, hisj family
Acfer_0142	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
Acfer_0143	ENOG4108WF2	Metal Dependent Phosphohydrolase
Acfer_0144	ENOG4108KGH	TRANSCRIPTIONal
Acfer_0146	ENOG4105QNR	S1 RNA binding domain protein
Acfer_0150	ENOG410811B	TRANSCRIPTIONal
Acfer_0152	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Acfer_0153	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Acfer_0154	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
Acfer_0155	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Acfer_0156	ENOG4108ZP8	Acetolactate synthase small subunit
Acfer_0157	ENOG4105C7K	acetolactate synthase
Acfer_0158	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
Acfer_0159	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
Acfer_0160	ENOG4105EB3	Histidine kinase
Acfer_0161	ENOG4105C7K	acetolactate synthase
Acfer_0162	ENOG4108ZP8	Acetolactate synthase small subunit
Acfer_0166	ENOG4105EUR	Domain-Containing protein
Acfer_0168	ENOG4105CIZ	coA-substrate-specific enzyme activase
Acfer_0172	ENOG4105CIH	Imidazole acetol-phosphate transaminase
Acfer_0173	ENOG4108R4R	Iron-regulated virulence regulatory protein
Acfer_0174	ENOG4105DR5	peptidase
Acfer_0175	ENOG4105U3E	Transcriptional regulator
Acfer_0176	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
Acfer_0177	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
Acfer_0178	ENOG4105C26	Dehydrogenase
Acfer_0185	ENOG4105KXQ	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
Acfer_0186	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
Acfer_0187	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
Acfer_0188	ENOG4105M56	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
Acfer_0189	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
Acfer_0192	ENOG4105C3M	thioredoxin reductase
Acfer_0194	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
Acfer_0196	ENOG4105VEQ	Cold shock protein
Acfer_0197	ENOG4105CHR	reductase
Acfer_0198	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
Acfer_0203	ENOG4108IJ0	Aspartate ammonia-lyase
Acfer_0204	ENOG4105VAW	lrga family
Acfer_0205	ENOG41067MG	lrgb family
Acfer_0206	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
Acfer_0208	ENOG4105C09	Bile acid
Acfer_0210	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
Acfer_0212	ENOG4105D81	ABC transporter, permease
Acfer_0213	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Acfer_0214	ENOG4105KME	endoribonuclease L-psp
Acfer_0215	ENOG4107HP6	Transcriptional regulator
Acfer_0217	ENOG4105X71	Membrane
Acfer_0221	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
Acfer_0222	ENOG4105D6U	Sodium Glutamate Symporter
Acfer_0223	ENOG4108V0P	LemA family
Acfer_0227	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Acfer_0228	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
Acfer_0229	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
Acfer_0230	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
Acfer_0231	ENOG4105C19	ABC transporter
Acfer_0232	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Acfer_0235	ENOG4105CCS	Glutamate formiminotransferase
Acfer_0236	ENOG4105CKU	formyltetrahydrofolate synthetase
Acfer_0237	ENOG410908R	Methenyltetrahydrofolate cyclohydrolase
Acfer_0241	ENOG4105C84	Histidine ammonia-lyase
Acfer_0243	ENOG4105C84	Histidine ammonia-lyase
Acfer_0244	ENOG4105CQB	FAD linked oxidase domain protein
Acfer_0246	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
Acfer_0248	ENOG4105CQ0	ABC transporter
Acfer_0249	ENOG4105BZG	amino acid carrier protein
Acfer_0250	ENOG4108ESE	uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center
Acfer_0251	ENOG4105C2N	RNA methyltransferase TrmH family group 3
Acfer_0252	ENOG4105QIV	RNA polymerase
Acfer_0257	ENOG4105WDJ	50S ribosomal protein L33
Acfer_0258	ENOG410683Z	Preprotein translocase SecE subunit
Acfer_0259	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
Acfer_0260	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
Acfer_0262	ENOG4108VZM	50s ribosomal protein L10
Acfer_0263	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
Acfer_0264	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
Acfer_0265	ENOG4108UMI	ABC transporter, permease
Acfer_0266	ENOG4105D01	(LipO)protein
Acfer_0267	ENOG4105CH2	amidohydrolase
Acfer_0268	ENOG4108VMM	UPF0756 membrane protein
Acfer_0269	ENOG4108Z29	Flavodoxin
Acfer_0271	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
Acfer_0272	ENOG4105D0S	secretion protein (HlyD
Acfer_0273	ENOG4105CJ1	ABC, transporter
Acfer_0274	ENOG4107QWP	ABC-2 type transporter
Acfer_0275	ENOG4107QWP	ABC-2 type transporter
Acfer_0281	ENOG4105CRQ	synthase (Component I)
Acfer_0282	ENOG4105DDQ	anthranilate synthase
Acfer_0284	ENOG4105DK0	Indole-3-glycerol phosphate synthase
Acfer_0285	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
Acfer_0286	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
Acfer_0287	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
Acfer_0288	ENOG4108KGH	TRANSCRIPTIONal
Acfer_0290	ENOG4105E2X	shikimate dehydrogenase
Acfer_0292	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
Acfer_0293	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
Acfer_0294	ENOG4105FF2	Type I DHQase
Acfer_0296	ENOG4105CIN	aminoacyl-histidine dipeptidase
Acfer_0298	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
Acfer_0300	ENOG4105DUM	transcriptional regulator, lysR family
Acfer_0302	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
Acfer_0304	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
Acfer_0305	ENOG4105KY8	Rubrerythrin
Acfer_0307	ENOG4105DUA	(citrate (pro-3S)-lyase ligase
Acfer_0308	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
Acfer_0309	ENOG4105C25	Primosomal protein n'
Acfer_0311	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
Acfer_0314	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
Acfer_0316	ENOG4105D9P	serine threonine protein kinase
Acfer_0317	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
Acfer_0321	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
Acfer_0323	ENOG4109015	Biopolymer transport protein exbD tolR
Acfer_0327	ENOG4105D6J	arsenicaL-resistance protein
Acfer_0330	ENOG4105KVH	Transcriptional regulator
Acfer_0332	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
Acfer_0333	ENOG4107QSS	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli (By similarity)
Acfer_0335	ENOG4107RUE	extracellular solute-binding protein family 1
Acfer_0336	ENOG4105D38	putrescine abc transporter
Acfer_0337	ENOG4105F38	ABC transporter, permease
Acfer_0339	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
Acfer_0341	ENOG4105K46	50S ribosomal protein l27
Acfer_0343	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Acfer_0344	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Acfer_0346	ENOG4105CFC	Transporter
Acfer_0347	ENOG4105CFC	Transporter
Acfer_0348	ENOG4108JJB	ABC transporter
Acfer_0349	ENOG4108JJB	ABC transporter
Acfer_0350	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
Acfer_0351	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
Acfer_0352	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
Acfer_0353	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
Acfer_0354	ENOG4108R6K	riboflavin synthase, subunit alpha
Acfer_0355	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
Acfer_0357	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
Acfer_0358	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
Acfer_0360	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
Acfer_0363	ENOG4108I5U	Uridine phosphorylase
Acfer_0364	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
Acfer_0367	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
Acfer_0369	ENOG4105K78	MarR family Transcriptional regulator
Acfer_0371	ENOG4105CK2	sodium dicarboxylate symporter
Acfer_0372	ENOG4105IGJ	Zn-dependent Hydrolase of the beta-lactamase fold protein
Acfer_0373	ENOG4107RSM	transcriptional regulator
Acfer_0374	ENOG4105VKD	bioY protein
Acfer_0375	ENOG4105CHU	acetyl-coa acetyltransferase
Acfer_0376	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
Acfer_0379	ENOG4108R96	Methyltransferase, YaeB family
Acfer_0384	ENOG4108R66	Conserved Protein
Acfer_0385	ENOG4105D05	Receptor
Acfer_0393	ENOG4108Z3G	3H domain protein
Acfer_0397	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
Acfer_0398	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
Acfer_0400	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
Acfer_0403	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
Acfer_0404	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
Acfer_0405	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
Acfer_0410	ENOG4105XGS	Covalent carrier of the coenzyme of citrate lyase (By similarity)
Acfer_0411	ENOG4106NZI	LysR family Transcriptional regulator
Acfer_0412	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
Acfer_0413	ENOG4105D63	family UPF0324
Acfer_0415	ENOG4105EJQ	L-serine dehydratase
Acfer_0417	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
Acfer_0418	ENOG4105DUM	transcriptional regulator, lysR family
Acfer_0419	ENOG41082DI	50s ribosomal protein l31
Acfer_0420	ENOG4105CBJ	Metal-dependent enzyme
Acfer_0421	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
Acfer_0422	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
Acfer_0423	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Acfer_0424	ENOG4108YZG	isomerase
Acfer_0425	ENOG4108UIC	UPF0340 protein
Acfer_0426	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
Acfer_0427	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
Acfer_0428	ENOG4108UK2	deaminase
Acfer_0435	ENOG4107YZX	Universal stress protein
Acfer_0436	ENOG4107YZX	Universal stress protein
Acfer_0437	ENOG4107YZX	Universal stress protein
Acfer_0438	ENOG4107YZX	Universal stress protein
Acfer_0439	ENOG41080TK	Universal stress protein
Acfer_0440	ENOG4107S6Z	Na H antiporter
Acfer_0441	ENOG4105BZG	amino acid carrier protein
Acfer_0442	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
Acfer_0444	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
Acfer_0445	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
Acfer_0448	ENOG4105C6Z	Gluconate
Acfer_0449	ENOG4105C3K	feS assembly ATPase SufC
Acfer_0450	ENOG4105DIW	FeS assembly protein SUFB
Acfer_0453	ENOG4107YH3	SUF system FeS assembly protein, NifU family
Acfer_0454	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
Acfer_0455	ENOG4105C5Y	PTS System
Acfer_0459	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Acfer_0463	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
Acfer_0467	ENOG4105K5M	30s ribosomal protein S16
Acfer_0471	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
Acfer_0472	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
Acfer_0475	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Acfer_0476	ENOG4105VFF	UPF0102 protein
Acfer_0477	ENOG4105C0P	Mg chelatase subunit ChlI
Acfer_0480	ENOG4105CGF	Aromatic amino acid aminotransferase
Acfer_0481	ENOG4107S03	uridine kinase
Acfer_0482	ENOG4105CHM	Aminotransferase
Acfer_0483	ENOG4105C1J	atp-dependent rna helicase
Acfer_0484	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
Acfer_0486	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
Acfer_0487	ENOG4108UJD	30S ribosomal protein S9
Acfer_0488	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
Acfer_0490	ENOG4105EAM	Na Pi-cotransporter
Acfer_0492	ENOG4106WTF	Glycosyl transferase, family 2
Acfer_0493	ENOG4105X1N	Glycosyl transferase family 8
Acfer_0495	ENOG4105K64	Glycosyl transferase, family 2
Acfer_0497	ENOG4105CB5	ATP-dependent DNA helicase recG
Acfer_0499	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
Acfer_0502	ENOG4105BZG	amino acid carrier protein
Acfer_0503	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
Acfer_0504	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
Acfer_0505	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
Acfer_0506	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
Acfer_0507	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
Acfer_0509	ENOG4105E4G	Type IV pilus
Acfer_0511	ENOG4107QHF	type ii secretion system protein e
Acfer_0512	ENOG4105EN6	Membrane
Acfer_0513	ENOG4108VPT	UPF0234 protein
Acfer_0515	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
Acfer_0517	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
Acfer_0518	ENOG4105VCQ	rubredoxin
Acfer_0520	ENOG4105ENX	hydrolase
Acfer_0521	ENOG4107QW4	alcohol dehydrogenase
Acfer_0523	ENOG4105DUM	transcriptional regulator, lysR family
Acfer_0524	ENOG4105CV8	reductase
Acfer_0532	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
Acfer_0533	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
Acfer_0537	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
Acfer_0539	ENOG4105EMY	transcriptional regulator
Acfer_0542	ENOG4108KP7	hydrolase
Acfer_0543	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
Acfer_0544	ENOG4105CHW	UPF0052 protein
Acfer_0549	ENOG4105E39	Enoyl-CoA hydratase
Acfer_0551	ENOG4105CY0	Metallo-Beta-Lactamase
Acfer_0552	ENOG4105CI3	gtp-binding protein typa
Acfer_0554	ENOG4105C0B	DNA polymerase III (alpha subunit)
Acfer_0555	ENOG4105BZJ	Electron transfer flavoprotein
Acfer_0556	ENOG4105C10	Electron transfer flavoprotein
Acfer_0557	ENOG4105CA9	Pyruvate kinase
Acfer_0560	ENOG4105C1A	potassium transporter peripheral membrane
Acfer_0561	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
Acfer_0562	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
Acfer_0565	ENOG4107YJ4	chain length determinant protein
Acfer_0570	ENOG4108KMV	Glycosyl transferase (Group 1
Acfer_0578	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
Acfer_0579	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
Acfer_0580	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
Acfer_0593	ENOG4107QYV	phosphohexose isomerase
Acfer_0594	ENOG4108JQC	penicillin-binding protein 1A
Acfer_0595	ENOG4105CAS	nag kinase
Acfer_0596	ENOG4105C8Y	Acetylornithine aminotransferase
Acfer_0597	ENOG4105DBV	ornithine carbamoyltransferase
Acfer_0599	ENOG4105CH7	arginosuccinase
Acfer_0601	ENOG4105C8B	TIGR00159 family
Acfer_0603	ENOG4105DZ0	fad dependent oxidoreductase
Acfer_0604	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
Acfer_0612	ENOG4105CEM	UPF0597 protein
Acfer_0613	ENOG4105C7N	Xanthine uracil vitamin C permease
Acfer_0615	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
Acfer_0616	ENOG4105D22	carbon starvation protein
Acfer_0618	ENOG4105ERH	Fumarylacetoacetate hydrolase
Acfer_0619	ENOG4105C9A	Phoh family
Acfer_0620	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
Acfer_0622	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
Acfer_0623	ENOG4105C37	(CBS) domain
Acfer_0624	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
Acfer_0626	ENOG4105CGK	Exodeoxyribonuclease III
Acfer_0628	ENOG4105C5Q	Transcriptional regulator
Acfer_0631	ENOG4107QM5	aconitate hydratase
Acfer_0634	ENOG4105C8T	Leucyl-tRNA synthetase
Acfer_0635	ENOG4105CXN	decarboxylase
Acfer_0636	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
Acfer_0637	ENOG4107QRG	dna polymerase iii
Acfer_0638	ENOG4105MA4	psp1 domain protein
Acfer_0639	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
Acfer_0640	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
Acfer_0641	ENOG4105DUM	transcriptional regulator, lysR family
Acfer_0645	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Acfer_0648	ENOG4107R0W	ABC transporter
Acfer_0649	ENOG4107R0W	ABC transporter
Acfer_0650	ENOG4105E5Q	amino acid AbC transporter
Acfer_0651	ENOG4105CDA	abc transporter atp-binding protein
Acfer_0652	ENOG4105MS2	ribosomal subunit Interface protein
Acfer_0653	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
Acfer_0654	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
Acfer_0657	ENOG4105CAK	Cell division ATP-binding protein ftsE
Acfer_0658	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
Acfer_0660	ENOG4105CN1	protease
Acfer_0661	ENOG4105BZU	Histidine kinase
Acfer_0662	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
Acfer_0664	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
Acfer_0665	ENOG41084A0	50s ribosomal protein L35
Acfer_0666	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
Acfer_0668	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
Acfer_0670	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Acfer_0677	ENOG4107QJQ	Mate efflux family protein
Acfer_0681	ENOG4105WCJ	ec 1.1.1.193
Acfer_0682	ENOG4105IH7	synthase
Acfer_0683	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
Acfer_0684	ENOG4105FJH	Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity)
Acfer_0686	ENOG4105BZU	Histidine kinase
Acfer_0687	ENOG4108Z40	Transcriptional regulator
Acfer_0691	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
Acfer_0693	ENOG4105C6K	Malic enzyme
Acfer_0694	ENOG4105D01	(LipO)protein
Acfer_0699	ENOG4107QPK	)-transporter
Acfer_0700	ENOG4105DAP	Nicotinate phosphoribosyltransferase
Acfer_0701	ENOG4105CSA	Coproporphyrinogen iii oxidase
Acfer_0702	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
Acfer_0703	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Acfer_0705	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Acfer_0709	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
Acfer_0710	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
Acfer_0711	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Acfer_0712	ENOG4107YU2	histidine triad (hIT) protein
Acfer_0714	ENOG4105KTH	gatB Yqey
Acfer_0715	ENOG4105CHM	Aminotransferase
Acfer_0718	ENOG4105CTP	PilT protein domain protein
Acfer_0719	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
Acfer_0720	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
Acfer_0721	ENOG4105C8N	cysteinyl-tRNA synthetase
Acfer_0722	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
Acfer_0726	ENOG4105D3Q	Sugar transferase
Acfer_0731	ENOG4105D5D	udp-galactopyranose mutase
Acfer_0738	ENOG4106TCE	
Acfer_0743	ENOG4105KPE	licD family
Acfer_0745	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
Acfer_0747	ENOG4105K64	Glycosyl transferase, family 2
Acfer_0757	ENOG4105FB9	CRISPR-associated protein
Acfer_0761	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
Acfer_0762	ENOG4105KCF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
Acfer_0767	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
Acfer_0769	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
Acfer_0775	ENOG4105C09	Bile acid
Acfer_0776	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
Acfer_0777	ENOG4105CDA	abc transporter atp-binding protein
Acfer_0778	ENOG4107RP9	extracellular solute-binding protein, family 3
Acfer_0779	ENOG4105EAD	ABC transporter
Acfer_0780	ENOG4105DRP	amino acid AbC transporter
Acfer_0783	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
Acfer_0785	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
Acfer_0786	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
Acfer_0788	ENOG4105F1A	Pyruvate formate-lyase
Acfer_0790	ENOG4105D01	(LipO)protein
Acfer_0791	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
Acfer_0792	ENOG4108YBP	pseudouridine synthase
Acfer_0799	ENOG4105BZU	Histidine kinase
Acfer_0805	ENOG4105CFC	Transporter
Acfer_0806	ENOG4105CD3	dihydroorotase
Acfer_0808	ENOG4105DZW	Dipeptidase
Acfer_0809	ENOG41080HT	Transcriptional regulator, arsr family
Acfer_0810	ENOG4105KZ7	phosphocarrier protein hpr
Acfer_0811	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
Acfer_0812	ENOG4105XTM	Inherit from NOG: Mn2 dependent serine threonine protein kinase
Acfer_0814	ENOG4105EGD	dinuclear metal center protein, YbgI family
Acfer_0815	ENOG4105EQI	Metal Dependent Phosphohydrolase
Acfer_0816	ENOG4105K63	Thioredoxin
Acfer_0817	ENOG4105CKK	Glycosyl transferase, family 2
Acfer_0820	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Acfer_0821	ENOG4105BZU	Histidine kinase
Acfer_0823	ENOG41084CE	UPF0342 protein
Acfer_0825	ENOG4108TVT	permease
Acfer_0827	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
Acfer_0828	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
Acfer_0829	ENOG4105CEY	Amp-dependent synthetase and ligase
Acfer_0831	ENOG4105BZU	Histidine kinase
Acfer_0832	ENOG4105WH1	Two component transcriptional regulator luxr family
Acfer_0834	ENOG4105CGH	5'-nucleotidase
Acfer_0843	ENOG4108ZSR	alkaline shock protein
Acfer_0846	ENOG4105M7K	Involved in the transcription termination process (By similarity)
Acfer_0847	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Acfer_0848	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
Acfer_0849	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
Acfer_0851	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
Acfer_0852	ENOG4105DX0	Hemolysin A
Acfer_0853	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
Acfer_0855	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
Acfer_0856	ENOG4108YZ4	nudix hydrolase
Acfer_0857	ENOG4105MCT	stage V sporulation protein S
Acfer_0859	ENOG4105E2Y	ABC, transporter
Acfer_0860	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
Acfer_0865	ENOG4105DCT	glycerol dehydrogenase
Acfer_0866	ENOG4107QJQ	Mate efflux family protein
Acfer_0868	ENOG4105BZU	Histidine kinase
Acfer_0876	ENOG4105C59	p-type ATPase
Acfer_0882	ENOG4105BZ1	(ABC) transporter
Acfer_0883	ENOG4105BZ1	(ABC) transporter
Acfer_0885	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
Acfer_0886	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
Acfer_0889	ENOG4107QRP	cobalamin biosynthesis protein CobW
Acfer_0893	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
Acfer_0894	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
Acfer_0896	ENOG4105VBH	UPF0297 protein
Acfer_0897	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
Acfer_0898	ENOG41068XD	UPF0473 protein
Acfer_0899	ENOG4105HHA	aminodeoxychorismate lyase
Acfer_0900	ENOG4105CFP	Peptidase U32
Acfer_0901	ENOG4105DC7	peptidase M24
Acfer_0902	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
Acfer_0903	ENOG4108TGR	phosphatase
Acfer_0906	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
Acfer_0911	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
Acfer_0912	ENOG4107RSM	transcriptional regulator
Acfer_0914	ENOG4105KGF	protein, YerC YecD
Acfer_0915	ENOG4108IQ6	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
Acfer_0918	ENOG4105CIH	Imidazole acetol-phosphate transaminase
Acfer_0919	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
Acfer_0920	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
Acfer_0921	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
Acfer_0922	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
Acfer_0923	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
Acfer_0924	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
Acfer_0925	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
Acfer_0926	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
Acfer_0927	ENOG4108IYU	L-aspartate oxidase
Acfer_0928	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
Acfer_0931	ENOG4105BZA	Phosphoglycerate kinase
Acfer_0933	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
Acfer_0934	ENOG4105DHT	Metal Dependent Phosphohydrolase
Acfer_0936	ENOG4105ETX	regulatoR
Acfer_0937	ENOG4105US7	Histidine kinase
Acfer_0938	ENOG4105D9R	oxidoreductase
Acfer_0942	ENOG4105ENX	hydrolase
Acfer_0944	ENOG4107SHS	Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites (By similarity)
Acfer_0950	ENOG4105ES4	Nitrilase
Acfer_0952	ENOG4107V2S	Transcriptional regulator
Acfer_0959	ENOG4107YDN	peptide deformylase
Acfer_0960	ENOG4105Y7M	Transcriptional regulator, TetR family
Acfer_0961	ENOG4107ZXU	DSBA oxidoreductase
Acfer_0962	ENOG4105C5X	domain protein
Acfer_0966	ENOG4107RSM	transcriptional regulator
Acfer_0974	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
Acfer_0976	ENOG4105C5I	Dehydrogenase
Acfer_0977	ENOG4105CSR	polyphosphate kinase 2
Acfer_0978	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
Acfer_0979	ENOG4105DFA	alanine racemase domain protein
Acfer_0980	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
Acfer_0985	ENOG4105BZJ	Electron transfer flavoprotein
Acfer_0986	ENOG4105C10	Electron transfer flavoprotein
Acfer_0987	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
Acfer_0994	ENOG4105KY8	Rubrerythrin
Acfer_0998	ENOG4105D2N	Aldolase
Acfer_0999	ENOG4105EMS	pseudouridine synthase
Acfer_1000	ENOG4105WMR	Protein CrcB homolog
Acfer_1003	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
Acfer_1004	ENOG4105C8M	UPF0272 protein
Acfer_1005	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
Acfer_1007	ENOG4108JJB	ABC transporter
Acfer_1009	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Acfer_1010	ENOG4107QIV	Cytochrome c biogenesis protein
Acfer_1012	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
Acfer_1013	ENOG4105CXI	aluminum resistance protein
Acfer_1014	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
Acfer_1015	ENOG4105C1J	atp-dependent rna helicase
Acfer_1016	ENOG4105CEV	competence damage-inducible protein
Acfer_1017	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
Acfer_1019	ENOG4105CNU	cell division protein FtsK
Acfer_1020	ENOG4105CN5	Metallo-Beta-Lactamase
Acfer_1024	ENOG4107FSS	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Acfer_1026	ENOG4105DB7	PHP domain protein
Acfer_1029	ENOG4105CZM	Major Facilitator
Acfer_1033	ENOG4105DM4	PTS System
Acfer_1034	ENOG4105DE4	1-phosphofructokinase
Acfer_1035	ENOG410901P	UPF0249 protein
Acfer_1036	ENOG4108SAX	Membrane
Acfer_1037	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
Acfer_1038	ENOG4105DFM	M18 family aminopeptidase
Acfer_1039	ENOG4105E5D	amino acid
Acfer_1040	ENOG4105CTZ	aminopeptidase c
Acfer_1044	ENOG4105BZ1	(ABC) transporter
Acfer_1045	ENOG4105BZ1	(ABC) transporter
Acfer_1046	ENOG4106NZI	LysR family Transcriptional regulator
Acfer_1047	ENOG4107ZCW	Low molecular weight phosphotyrosine protein phosphatase
Acfer_1053	ENOG4108PZQ	Inner membrane protein YeeR
Acfer_1060	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Acfer_1067	ENOG4105CBX	hi0933 family
Acfer_1068	ENOG4105DUM	transcriptional regulator, lysR family
Acfer_1070	ENOG4105D4T	Citrate transporter
Acfer_1073	ENOG4105MRD	Phage derived protein Gp49-like (DUF891)
Acfer_1080	ENOG4108ES9	ParB domain protein nuclease
Acfer_1104	ENOG4107YCY	Transcriptional regulator
Acfer_1109	ENOG4105M6F	mutator MutT protein
Acfer_1125	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
Acfer_1150	ENOG4107RDT	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
Acfer_1161	ENOG4105MRD	Phage derived protein Gp49-like (DUF891)
Acfer_1166	ENOG4105D7V	transposase
Acfer_1168	ENOG4105WAB	arsR family transcriptional regulator
Acfer_1173	ENOG4105DZR	Type I site-specific deoxyribonuclease
Acfer_1175	ENOG41082EK	Restriction modification system DNA (Specificity
Acfer_1178	ENOG4105IGJ	Zn-dependent Hydrolase of the beta-lactamase fold protein
Acfer_1179	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
Acfer_1180	ENOG4108UMI	ABC transporter, permease
Acfer_1188	ENOG4105D1F	ATP-binding protein
Acfer_1193	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
Acfer_1195	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
Acfer_1196	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
Acfer_1198	ENOG4107Z0P	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
Acfer_1200	ENOG4108UB3	Thiamine monophosphate
Acfer_1201	ENOG4105MAX	Superoxide reductase
Acfer_1203	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
Acfer_1205	ENOG4105D6U	Sodium Glutamate Symporter
Acfer_1207	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Acfer_1208	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
Acfer_1209	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
Acfer_1211	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
Acfer_1212	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
Acfer_1213	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Acfer_1215	ENOG4107QMH	DNA methylase
Acfer_1224	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Acfer_1225	ENOG4105EEI	dihydropteroate synthase
Acfer_1226	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
Acfer_1227	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
Acfer_1228	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
Acfer_1230	ENOG4107RUZ	Sss sodium solute transporter superfamily
Acfer_1231	ENOG4107WCI	zn-dependent hydrolase of the beta-lactamase fold-like protein
Acfer_1232	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
Acfer_1233	ENOG4105D6E	homoserine dehydrogenase
Acfer_1234	ENOG41090I5	UPF0735 ACT domain-containing protein
Acfer_1235	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
Acfer_1236	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
Acfer_1238	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
Acfer_1239	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
Acfer_1241	ENOG4105CAT	Cytidine monophosphate kinase
Acfer_1242	ENOG4105CBX	hi0933 family
Acfer_1243	ENOG4105FE9	pseudouridine synthase
Acfer_1244	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
Acfer_1245	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
Acfer_1246	ENOG4108Z4T	Peptidase M50
Acfer_1247	ENOG4105EUM	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor (By similarity)
Acfer_1248	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Acfer_1249	ENOG4108FW6	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
Acfer_1250	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
Acfer_1251	ENOG4105C79	DNA protecting protein DprA
Acfer_1252	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
Acfer_1255	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
Acfer_1260	ENOG4105C0D	helicase
Acfer_1262	ENOG4105ER2	Ompa motb domain protein
Acfer_1269	ENOG4108FUT	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
Acfer_1270	ENOG4105C09	Bile acid
Acfer_1271	ENOG4105CJW	magnesium transporter
Acfer_1273	ENOG4105DR4	Methyltransferase
Acfer_1275	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
Acfer_1276	ENOG4105C12	Phosphoribosylglycinamide synthetase
Acfer_1277	ENOG4105DC1	bifunctional purine biosynthesis protein purh
Acfer_1278	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
Acfer_1279	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
Acfer_1281	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
Acfer_1283	ENOG4105C98	muts2 protein
Acfer_1284	ENOG4105CFP	Peptidase U32
Acfer_1293	ENOG4108VAU	general secretion pathway protein G
Acfer_1295	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
Acfer_1296	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
Acfer_1297	ENOG4105K67	small basic protein
Acfer_1300	ENOG4105CPF	Cell wall formation (By similarity)
Acfer_1301	ENOG4105DFU	Cell wall formation (By similarity)
Acfer_1302	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
Acfer_1304	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
Acfer_1305	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
Acfer_1306	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
Acfer_1308	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
Acfer_1309	ENOG4108V6E	Cell division protein mraZ
Acfer_1311	ENOG4107XPQ	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
Acfer_1312	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
Acfer_1313	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
Acfer_1314	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
Acfer_1315	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
Acfer_1316	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
Acfer_1317	ENOG4105CD3	dihydroorotase
Acfer_1318	ENOG4105CXT	aspartate transcarbamylase
Acfer_1320	ENOG4105CFI	type iii restriction protein res subunit
Acfer_1327	ENOG4105BZ8	glutamate synthase
Acfer_1328	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
Acfer_1329	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
Acfer_1330	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
Acfer_1332	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
Acfer_1333	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
Acfer_1336	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
Acfer_1338	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
Acfer_1341	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
Acfer_1346	ENOG4107GFK	fumarate
Acfer_1347	ENOG4106DSS	Tartrate dehydratase subunit alpha
Acfer_1348	ENOG4105C8P	)-transporter
Acfer_1349	ENOG4108WYP	Transcriptional regulator
Acfer_1350	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
Acfer_1351	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
Acfer_1352	ENOG4105DTN	riboflavin biosynthesis protein ribF
Acfer_1353	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
Acfer_1354	ENOG4105SFS	phosphoesterase RecJ domain protein
Acfer_1355	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
Acfer_1356	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
Acfer_1356	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
Acfer_1358	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
Acfer_1359	ENOG4105CHV	Transcription elongation factor NusA
Acfer_1360	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
Acfer_1361	ENOG4108JQC	penicillin-binding protein 1A
Acfer_1362	ENOG4107QSA	Oxaloacetate decarboxylase
Acfer_1363	ENOG4107RT5	aminobenzoyl-glutamate utilization protein B
Acfer_1365	ENOG4108J5H	Homocysteine s-methyltransferase
Acfer_1371	ENOG4105KT7	mgtC SapB transporter
Acfer_1372	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
Acfer_1373	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
Acfer_1374	ENOG4105DZP	Membrane-associated zinc metalloprotease
Acfer_1375	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
Acfer_1377	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
Acfer_1379	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
Acfer_1380	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
Acfer_1381	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
Acfer_1382	ENOG4105CE9	30S ribosomal protein S2
Acfer_1383	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
Acfer_1385	ENOG4105CM2	brancheD-chain amino acid aminotransferase
Acfer_1386	ENOG4105BZU	Histidine kinase
Acfer_1387	ENOG410620I	Diguanylate cyclase
Acfer_1388	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
Acfer_1389	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
Acfer_1391	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
Acfer_1392	ENOG4105CHR	reductase
Acfer_1393	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
Acfer_1394	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
Acfer_1395	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
Acfer_1396	ENOG4108VVV	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism (By similarity)
Acfer_1397	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
Acfer_1398	ENOG41067VY	50S ribosomal protein L32
Acfer_1400	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
Acfer_1403	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
Acfer_1404	ENOG4106H78	methyltransferase
Acfer_1411	ENOG4107RT5	aminobenzoyl-glutamate utilization protein B
Acfer_1415	ENOG4107QW8	radical SAM domain protein
Acfer_1418	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
Acfer_1419	ENOG41084KE	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
Acfer_1420	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
Acfer_1421	ENOG4105KC4	UPF0296 protein
Acfer_1422	ENOG4105DSJ	YicC domain protein
Acfer_1424	ENOG4105F23	Fibronectin-binding protein
Acfer_1425	ENOG4105C01	Dihydroxy-acid dehydratase
Acfer_1427	ENOG4105CRK	lysyL-tRNA synthetase
Acfer_1429	ENOG4105F4P	)-transporter
Acfer_1430	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
Acfer_1431	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
Acfer_1432	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
Acfer_1434	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
Acfer_1436	ENOG41069ER	domain protein
Acfer_1437	ENOG4105F8V	Hydrolase, tatD family
Acfer_1438	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
Acfer_1441	ENOG4105BZU	Histidine kinase
Acfer_1443	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
Acfer_1444	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
Acfer_1445	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
Acfer_1446	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
Acfer_1447	ENOG4105C7B	Threonine dehydratase
Acfer_1448	ENOG4105DFT	pur operon repressor
Acfer_1449	ENOG4105DRR	Transcriptional regulator, GntR family
Acfer_1450	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
Acfer_1451	ENOG4108JYZ	YitT family
Acfer_1452	ENOG4105D6U	Sodium Glutamate Symporter
Acfer_1455	ENOG4105KQC	Competence protein
Acfer_1457	ENOG4107R0W	ABC transporter
Acfer_1458	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Acfer_1460	ENOG4108UQV	Membrane
Acfer_1461	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
Acfer_1464	ENOG4105BZ1	(ABC) transporter
Acfer_1465	ENOG4105BZ1	(ABC) transporter
Acfer_1467	ENOG4105C7H	Helicase, RecD TraA family
Acfer_1471	ENOG4108IJ2	phosphate acetyltransferase
Acfer_1473	ENOG4105DFM	M18 family aminopeptidase
Acfer_1475	ENOG4105E39	Enoyl-CoA hydratase
Acfer_1476	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
Acfer_1477	ENOG4105C1G	acyl-Coa dehydrogenase
Acfer_1478	ENOG4105CHU	acetyl-coa acetyltransferase
Acfer_1482	ENOG4105CAG	UPF0210 protein
Acfer_1483	ENOG4105VUC	UPF0237 protein
Acfer_1485	ENOG4105C8V	SAICAR synthetase
Acfer_1486	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
Acfer_1489	ENOG4105C3M	thioredoxin reductase
Acfer_1494	ENOG4105VPX	protein, conserved in bacteria
Acfer_1495	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
Acfer_1496	ENOG4108RWN	rrna methyltransferase
Acfer_1497	ENOG4107ZYR	domain protein
Acfer_1498	ENOG4105CZN	Potassium uptake protein
Acfer_1500	ENOG4105D9Q	decarboxylase (Beta subunit)
Acfer_1505	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
Acfer_1506	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
Acfer_1507	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
Acfer_1508	ENOG4105C34	Pseudouridine synthase
Acfer_1509	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
Acfer_1510	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
Acfer_1512	ENOG4105C9M	aspartyl-trna synthetase
Acfer_1513	ENOG4105CUT	histidyl-tRNA synthetase
Acfer_1514	ENOG4105C02	permease
Acfer_1515	ENOG4105C5X	domain protein
Acfer_1516	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
Acfer_1517	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
Acfer_1518	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
Acfer_1521	ENOG4107SBW	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
Acfer_1522	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
Acfer_1526	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
Acfer_1527	ENOG4105JFG	SpoIID LytB domain protein
Acfer_1528	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
Acfer_1529	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
Acfer_1530	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
Acfer_1531	ENOG4105CDY	transcriptional regulatory protein
Acfer_1533	ENOG4105D98	threonine synthase
Acfer_1534	ENOG4105C4K	Nad synthetase
Acfer_1537	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
Acfer_1538	ENOG4108RAC	Rubrerythrin
Acfer_1541	ENOG4105D01	(LipO)protein
Acfer_1550	ENOG4108UXE	Protein tyrosine phosphatase
Acfer_1551	ENOG4105D6J	arsenicaL-resistance protein
Acfer_1554	ENOG4105DY9	regulatoR
Acfer_1557	ENOG4108VKG	metal-dependent hydrolase
Acfer_1558	ENOG4108JU6	CBS domain protein
Acfer_1561	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
Acfer_1570	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
Acfer_1574	ENOG4106P55	Transcriptional regulator
Acfer_1575	ENOG4105C1G	acyl-Coa dehydrogenase
Acfer_1576	ENOG4105CNW	domain protein
Acfer_1580	ENOG41072GX	Peptidase M22 Glycoprotease
Acfer_1581	ENOG4105K8N	protein family UPF0079, ATPase
Acfer_1582	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
Acfer_1583	ENOG4105C1G	acyl-Coa dehydrogenase
Acfer_1585	ENOG41069ER	domain protein
Acfer_1586	ENOG4105C5F	glutamine synthetase
Acfer_1589	ENOG4105DTQ	mandelate racemase muconate lactonizing
Acfer_1590	ENOG4107QSE	Dipeptidase
Acfer_1592	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
Acfer_1593	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
Acfer_1594	ENOG4105VKD	bioY protein
Acfer_1596	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Acfer_1597	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
Acfer_1598	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
Acfer_1599	ENOG41060GV	RNA binding s1 domain protein
Acfer_1604	ENOG4105D1Z	hydroxypyruvate reductase
Acfer_1605	ENOG4105D64	Mechanosensitive ion channel
Acfer_1606	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
Acfer_1607	ENOG4105E2X	shikimate dehydrogenase
Acfer_1609	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
Acfer_1611	ENOG4105D49	3-dehydroquinate synthase
Acfer_1613	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
Acfer_1615	ENOG4105D1F	ATP-binding protein
Acfer_1617	ENOG4105K70	DNA-binding protein
Acfer_1618	ENOG4105DXN	mazG family
Acfer_1619	ENOG4105CKP	Polysaccharide Biosynthesis Protein
Acfer_1620	ENOG4108JA2	transcriptioN-repair coupling factor
Acfer_1621	ENOG4105CBT	Fructose-1,6-bisphosphatase
Acfer_1622	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
Acfer_1623	ENOG4105C75	arginyL-tRNA synthetase
Acfer_1625	ENOG4105CK7	Sodium proline symporter
Acfer_1627	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
Acfer_1628	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
Acfer_1629	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
Acfer_1630	ENOG4105D1H	recombination factor protein RarA
Acfer_1633	ENOG4105D5T	phosphonate abc transporter
Acfer_1634	ENOG4105C7J	ABC transporter, permease
Acfer_1638	ENOG4108K0D	peptidase, M48
Acfer_1639	ENOG4107RFY	SbcCD D subunit
Acfer_1640	ENOG4105EYH	Exonuclease
Acfer_1641	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
Acfer_1643	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
Acfer_1644	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
Acfer_1646	ENOG4105CFC	Transporter
Acfer_1648	ENOG4105DI5	UPF0365 protein
Acfer_1651	ENOG4105XA0	heptosyltransferase ii
Acfer_1652	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
Acfer_1653	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
Acfer_1654	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
Acfer_1655	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
Acfer_1658	ENOG4108MJ5	VirK protein
Acfer_1662	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
Acfer_1666	ENOG4105ZU5	s-layer protein
Acfer_1668	ENOG4105ZU5	s-layer protein
Acfer_1669	ENOG4105ZU5	s-layer protein
Acfer_1670	ENOG4105ZU5	s-layer protein
Acfer_1672	ENOG4108R0D	protein with myosin-like
Acfer_1676	ENOG4108IUZ	ABC transporter
Acfer_1680	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
Acfer_1681	ENOG4105C2X	Arabinose 5-phosphate isomerase
Acfer_1682	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
Acfer_1683	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
Acfer_1684	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
Acfer_1685	ENOG4105BZ1	(ABC) transporter
Acfer_1686	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Acfer_1687	ENOG4105GYT	Protein of unknown function (DUF1009)
Acfer_1688	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Acfer_1689	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Acfer_1692	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Acfer_1696	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Acfer_1700	ENOG4105DHJ	ABC, transporter
Acfer_1702	ENOG4105S1Z	Stage IV sporulation protein B
Acfer_1704	ENOG4108HQ0	Exopolysaccharide biosynthesis protein
Acfer_1705	ENOG4105DFF	Rod shape-determining protein mreb
Acfer_1706	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
Acfer_1711	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
Acfer_1712	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
Acfer_1713	ENOG4108Q71	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
Acfer_1715	ENOG4107SM1	it plays a direct role in the translocation of protons across the membrane (By similarity)
Acfer_1717	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
Acfer_1718	ENOG4105ESV	Glycosyl transferase, family 4
Acfer_1721	ENOG4107QMU	Mate efflux family protein
Acfer_1722	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
Acfer_1726	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
Acfer_1727	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
Acfer_1728	ENOG4105C6E	dna polymerase iii
Acfer_1729	ENOG4105CQB	FAD linked oxidase domain protein
Acfer_1730	ENOG4108Z6B	deaminase
Acfer_1731	ENOG4105CVG	Homoserine O-transsuccinylase
Acfer_1734	ENOG4105DIN	metallophosphoesterase
Acfer_1735	ENOG4105WMR	Protein CrcB homolog
Acfer_1736	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
Acfer_1740	ENOG4105E1F	short-chain dehydrogenase reductase
Acfer_1741	ENOG4107TCE	N-acetyltransferase
Acfer_1745	ENOG4105CK2	sodium dicarboxylate symporter
Acfer_1746	ENOG4105CTX	dehydratase
Acfer_1747	ENOG4105CTX	dehydratase
Acfer_1748	ENOG4105DUM	transcriptional regulator, lysR family
Acfer_1749	ENOG4105CIN	aminoacyl-histidine dipeptidase
Acfer_1754	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
Acfer_1756	ENOG4105D82	Glutamate dehydrogenase
Acfer_1758	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
Acfer_1760	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Acfer_1761	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
Acfer_1762	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Acfer_1763	ENOG4105C28	cystathionine
Acfer_1764	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
Acfer_1770	ENOG4105CKT	filamentous hemagglutinin
Acfer_1773	ENOG4105CKT	filamentous hemagglutinin
Acfer_1776	ENOG4105CKT	filamentous hemagglutinin
Acfer_1777	ENOG4105CKT	filamentous hemagglutinin
Acfer_1779	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
Acfer_1780	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
Acfer_1781	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Acfer_1782	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
Acfer_1783	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
Acfer_1787	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
Acfer_1791	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
Acfer_1793	ENOG4105Q2H	domain protein
Acfer_1796	ENOG4105D7W	serine acetyltransferase
Acfer_1797	ENOG4105C6T	cysteine synthase
Acfer_1801	ENOG4105C8J	)-transporter
Acfer_1802	ENOG4105C8J	)-transporter
Acfer_1806	ENOG4105CH2	amidohydrolase
Acfer_1807	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
Acfer_1808	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
Acfer_1811	ENOG4107RSM	transcriptional regulator
Acfer_1812	ENOG4105CYC	Transferase
Acfer_1814	ENOG4105DCU	2-hydroxyglutaryl-CoA dehydratase
Acfer_1815	ENOG4105CMH	dehydratase
Acfer_1816	ENOG4105CIZ	coA-substrate-specific enzyme activase
Acfer_1817	ENOG4107QX3	carboxylase
Acfer_1818	ENOG4107UHT	Glutaconate CoA-transferase
Acfer_1819	ENOG4105DMN	coenzyme A transferase
Acfer_1820	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
Acfer_1821	ENOG4105C03	ribonuclease
Acfer_1824	ENOG4105CNI	cell division protein FtsW
Acfer_1828	ENOG4105DFF	Rod shape-determining protein mreb
Acfer_1829	ENOG4105W5Q	DNA repair protein (RadC
Acfer_1830	ENOG4108Z03	MAF-like protein
Acfer_1834	ENOG4105D9Q	decarboxylase (Beta subunit)
Acfer_1835	ENOG4105PV1	biotin lipoyl attachment domaiN-containing protein
Acfer_1837	ENOG4107QX3	carboxylase
Acfer_1838	ENOG4105CYC	Transferase
Acfer_1840	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
Acfer_1844	ENOG4105CI2	imidazolone-5-propionate hydrolase
Acfer_1845	ENOG4105CGP	Urocanate hydratase
Acfer_1846	ENOG4107QW8	radical SAM domain protein
Acfer_1848	ENOG4105CUB	amino acid
Acfer_1849	ENOG4108Z86	Glutamine amidotransferase
Acfer_1850	ENOG4105C3R	Methionine synthase
Acfer_1852	ENOG4105SYT	Methylenetetrahydrofolate reductase
Acfer_1853	ENOG4107U9B	transcriptional regulator
Acfer_1854	ENOG4108UMN	azlc family
Acfer_1855	ENOG4105KMT	branched-chain amino acid
Acfer_1856	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
Acfer_1858	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
Acfer_1860	ENOG4105C9X	ppx gppa phosphatase
Acfer_1862	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Acfer_1863	ENOG4105CFC	Transporter
Acfer_1864	ENOG4105CEN	a g-specific adenine glycosylase
Acfer_1865	ENOG4105E09	nadh pyrophosphatase
Acfer_1866	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
Acfer_1868	ENOG4105P4J	Allophanate hydrolase, subunit 1
Acfer_1869	ENOG4105C5A	transporter
Acfer_1870	ENOG4105E7W	lamb ycsf family protein
Acfer_1871	ENOG4105C5A	transporter
Acfer_1872	ENOG4105QZY	s-layer domain protein
Acfer_1873	ENOG4108Z3G	3H domain protein
Acfer_1878	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
Acfer_1880	ENOG4105G6Z	alkaline phosphatase
Acfer_1882	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
Acfer_1883	ENOG4105E2Z	phosphate ABC transporter (Permease
Acfer_1885	ENOG4105CVA	phosphate
Acfer_1888	ENOG4105CYW	agmatinase
Acfer_1889	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
Acfer_1890	ENOG4105CXN	decarboxylase
Acfer_1894	ENOG4105C5H	ABC transporter
Acfer_1895	ENOG4105D5B	Sulfite reductase, subunit A
Acfer_1896	ENOG4107SHJ	sulfite reductase subunit b
Acfer_1897	ENOG410810Y	Sulfite reductase
Acfer_1898	ENOG4108RE9	Phosphodiesterase
Acfer_1901	ENOG4108ZT0	50S ribosomal protein l17
Acfer_1902	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Acfer_1903	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
Acfer_1905	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Acfer_1906	ENOG41067V7	50S ribosomal protein L36
Acfer_1908	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
Acfer_1909	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
Acfer_1911	ENOG4105VPB	50S ribosomal protein L30
Acfer_1912	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
Acfer_1913	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
Acfer_1914	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
Acfer_1915	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
Acfer_1916	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
Acfer_1917	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Acfer_1918	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
Acfer_1919	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
Acfer_1920	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
Acfer_1922	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
Acfer_1923	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
Acfer_1924	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
Acfer_1925	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
Acfer_1926	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Acfer_1927	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
Acfer_1928	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
Acfer_1929	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
Acfer_1933	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
Acfer_1934	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
Acfer_1935	ENOG4105XPM	ribosomal protein
Acfer_1940	ENOG4105C5H	ABC transporter
Acfer_1941	ENOG4105CMR	udp-glucose 4-epimerase
Acfer_1954	ENOG4105BZ8	glutamate synthase
Acfer_1955	ENOG4107QHI	-hydrogenase
Acfer_1956	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
Acfer_1957	ENOG4105PNM	synthesis protein
Acfer_1958	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Acfer_1958	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Acfer_1961	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Acfer_1963	ENOG4105G5W	regulator Fur family
Acfer_1966	ENOG4108KB2	LysR family Transcriptional regulator
Acfer_1967	ENOG4107RSM	transcriptional regulator
Acfer_1968	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
Acfer_1970	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
Acfer_1971	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Acfer_1972	ENOG4105C5Q	Transcriptional regulator
Acfer_1973	ENOG4107QM5	aconitate hydratase
Acfer_1974	ENOG4105C7F	AcnD-accessory protein PrpF
Acfer_1976	ENOG4105GAK	amidohydrolase 2
Acfer_1980	ENOG4105CD3	dihydroorotase
Acfer_1981	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
Acfer_1982	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
Acfer_1983	ENOG4107RSM	transcriptional regulator
Acfer_1986	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
Acfer_1987	ENOG4105C8P	)-transporter
Acfer_1988	ENOG4108MCI	Transcriptional regulator, ARAC family
Acfer_1990	ENOG4105KME	endoribonuclease L-psp
Acfer_1992	ENOG4105CK7	Sodium proline symporter
Acfer_1994	ENOG4107RCH	Diaminopropionate ammonia-lyase
Acfer_1995	ENOG4108JUB	Transcriptional regulator
Acfer_1997	ENOG4107YUH	hydrolase
Acfer_1999	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Acfer_2000	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
Acfer_2001	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Acfer_2005	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
Acfer_2006	ENOG4107HP6	Transcriptional regulator
Acfer_2008	ENOG4105CH2	amidohydrolase
Acfer_2011	ENOG4105F04	LysR family Transcriptional regulator
Acfer_2013	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
Acfer_2015	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
Acfer_2016	ENOG4105CXK	mandelate racemase muconate lactonizing
Acfer_2023	ENOG4108M0I	Transcriptional regulator
Acfer_2024	ENOG4105K3M	)-transporter
Acfer_2028	ENOG4107QWE	)-transporter
Acfer_2031	ENOG4105JSC	dimethylmenaquinone methyltransferase
Acfer_2032	ENOG4107RSM	transcriptional regulator
Acfer_2034	ENOG4108JQ1	Dehydrogenase
Acfer_2035	ENOG4107QSV	RmuC domain protein
Acfer_2036	ENOG41064MX	Tetr family transcriptional regulator
Acfer_2039	ENOG4105EUR	Domain-Containing protein
Acfer_2041	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
Acfer_2043	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
Acfer_2046	ENOG4108JJB	ABC transporter
Acfer_2047	ENOG4108JJB	ABC transporter
Acfer_2050	ENOG4107Y70	Heat shock protein
Acfer_2053	ENOG4105C9Q	fumarate hydratase class II
Acfer_2054	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
Acfer_2057	ENOG4105BZ8	glutamate synthase
Acfer_2062	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Acfer_2063	ENOG4105C87	Aminotransferase class I and II
Acfer_2065	ENOG4105ETE	Transcriptional regulator (LacI family
Acfer_2067	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
Acfer_2071	ENOG4105FA0	parb-like partition protein
Acfer_2072	ENOG4107QJE	Chromosome Partitioning Protein
Acfer_2073	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
Acfer_2075	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
Acfer_2076	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
Acfer_2077	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
Acfer_2080	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
Acfer_2081	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
Acfer_2084	ENOG4107RT5	aminobenzoyl-glutamate utilization protein B
Acfer_2085	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
Acfer_2086	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
Acfer_2087	ENOG4105HDK	L-asparaginase
Acfer_2090	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
Acfer_2091	ENOG4105BZU	Histidine kinase