locus-tag	class	description
NQ562_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NQ562_00010	COG0592	DNA-directed DNA polymerase activity
NQ562_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NQ562_00030	COG0187	DNA topoisomerase II activity
NQ562_00040	COG0730	response to heat
NQ562_00045	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NQ562_00055	COG2801	Transposase and inactivated derivatives
NQ562_00100	COG0440	acetolactate synthase activity
NQ562_00105	COG0028	Belongs to the TPP enzyme family
NQ562_00110	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NQ562_00120	COG0385	Bile acid
NQ562_00125	COG0129	dihydroxy-acid dehydratase activity
NQ562_00140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NQ562_00150	COG0803	Belongs to the bacterial solute-binding protein 9 family
NQ562_00155	COG1121	(ABC) transporter
NQ562_00160	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NQ562_00175	COG0583	DNA-binding transcription factor activity
NQ562_00180	COG2851	Citrate transporter
NQ562_00250	COG1288	antiporter activity
NQ562_00260	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NQ562_00270	COG1691	(AIR) carboxylase
NQ562_00305	COG1971	Probably functions as a manganese efflux pump
NQ562_00310	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NQ562_00315	COG0482	sulfurtransferase activity
NQ562_00335	COG0360	Binds together with S18 to 16S ribosomal RNA
NQ562_00340	COG0629	single-stranded DNA binding
NQ562_00345	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NQ562_00365	COG1131	(ABC) transporter
NQ562_00370	COG0842	Transport permease protein
NQ562_00375	COG0842	Transport permease protein
NQ562_00385	COG0583	DNA-binding transcription factor activity
NQ562_00395	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NQ562_00405	COG2706	6-phosphogluconolactonase activity
NQ562_00410	COG5016	pyruvate
NQ562_00410	COG0511	ligase activity, forming carbon-carbon bonds
NQ562_00420	COG1122	ATPase activity
NQ562_00425	COG1122	ATPase activity
NQ562_00440	COG1269	ATP hydrolysis coupled proton transport
NQ562_00445	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NQ562_00460	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
NQ562_00465	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
NQ562_00470	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
NQ562_00475	COG1394	ATPase activity, coupled to movement of substances
NQ562_00485	COG0745	RESPONSE REGULATOR receiver
NQ562_00490	COG5002	protein histidine kinase activity
NQ562_00490	COG5000	phosphorelay sensor kinase activity
NQ562_00500	COG3885	ferrous iron binding
NQ562_00500	COG2078	PFAM AMMECR1 domain protein
NQ562_00505	COG1573	uracil-dna glycosylase
NQ562_00525	COG2878	Part of a membrane complex involved in electron transport
NQ562_00525	COG1148	4fe-4S ferredoxin, iron-sulfur binding domain protein
NQ562_00530	COG4657	Part of a membrane complex involved in electron transport
NQ562_00535	COG4660	Part of a membrane complex involved in electron transport
NQ562_00540	COG4659	FMN binding
NQ562_00545	COG4658	electron transport chain
NQ562_00550	COG4656	Part of a membrane complex involved in electron transport
NQ562_00560	COG0791	NLP P60 protein
NQ562_00565	COG2204	response regulator
NQ562_00570	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NQ562_00575	COG0772	Belongs to the SEDS family
NQ562_00580	COG0768	penicillin binding
NQ562_00585	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NQ562_00595	COG0318	PFAM AMP-dependent synthetase and ligase
NQ562_00620	COG1966	Carbon starvation protein
NQ562_00625	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NQ562_00630	COG3047	cAMP biosynthetic process
NQ562_00630	COG2885	chlorophyll binding
NQ562_00635	COG0277	FAD linked oxidase domain protein
NQ562_00640	COG0405	Gamma-glutamyltransferase
NQ562_00645	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NQ562_00650	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NQ562_00670	COG2084	Dehydrogenase
NQ562_00680	COG1176	ABC-type spermidine putrescine transport system, permease component I
NQ562_00685	COG3842	ATPase activity
NQ562_00690	COG0251	oxidation-reduction process
NQ562_00710	COG0010	Belongs to the arginase family
NQ562_00715	COG1414	Transcriptional regulator
NQ562_00735	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NQ562_00750	COG1704	LemA family
NQ562_00775	COG2801	Transposase and inactivated derivatives
NQ562_00795	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NQ562_00800	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NQ562_00805	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NQ562_00815	COG1136	(ABC) transporter
NQ562_00820	COG1136	(ABC) transporter
NQ562_00820	COG0577	efflux transmembrane transporter activity
NQ562_00830	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
NQ562_00835	COG1914	H( )-stimulated, divalent metal cation uptake system
NQ562_00840	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
NQ562_00845	COG1984	allophanate hydrolase subunit 2
NQ562_00855	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
NQ562_00865	COG1194	a g-specific adenine glycosylase
NQ562_00870	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NQ562_00880	COG2116	formate transmembrane transporter activity
NQ562_00910	COG2801	Transposase and inactivated derivatives
NQ562_00915	COG3829	transcription factor binding
NQ562_00920	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NQ562_00925	COG2986	histidine ammonia-lyase
NQ562_00930	COG2056	Na+-H+ antiporter family
NQ562_00940	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NQ562_00960	COG2172	sigma factor antagonist activity
NQ562_00970	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NQ562_00980	COG4770	biotin carboxylase activity
NQ562_00985	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
NQ562_01015	COG2003	Belongs to the UPF0758 family
NQ562_01020	COG1077	Cell shape determining protein MreB Mrl
NQ562_01040	COG0772	Belongs to the SEDS family
NQ562_01055	COG1530	ribonuclease E activity
NQ562_01060	COG0617	tRNA 3'-terminal CCA addition
NQ562_01065	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NQ562_01070	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NQ562_01075	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NQ562_01080	COG1924	4 iron, 4 sulfur cluster binding
NQ562_01085	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
NQ562_01090	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
NQ562_01095	COG1328	CTP reductase activity
NQ562_01105	COG2801	Transposase and inactivated derivatives
NQ562_01115	COG1473	amidohydrolase
NQ562_01130	COG1607	acyl-coa hydrolase
NQ562_01140	COG0733	neurotransmitter:sodium symporter activity
NQ562_01150	COG0561	phosphatase activity
NQ562_01155	COG2707	UPF0756 membrane protein
NQ562_01160	COG1376	ErfK ybiS ycfS ynhG family protein
NQ562_01170	COG0735	belongs to the Fur family
NQ562_01175	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NQ562_01185	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NQ562_01190	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NQ562_01200	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
NQ562_01205	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
NQ562_01210	COG2801	Transposase and inactivated derivatives
NQ562_01220	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NQ562_01225	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NQ562_01230	COG0242	peptide deformylase activity
NQ562_01235	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NQ562_01245	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NQ562_01245	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NQ562_01250	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NQ562_01255	COG0631	protein serine/threonine phosphatase activity
NQ562_01260	COG0515	serine threonine protein kinase
NQ562_01260	COG2815	serine threonine protein kinase
NQ562_01270	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NQ562_01290	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NQ562_01290	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NQ562_01300	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NQ562_01305	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NQ562_01315	COG1418	mRNA catabolic process
NQ562_01330	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
NQ562_01345	COG1151	hydroxylamine reductase activity
NQ562_01365	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NQ562_01370	COG0436	Aminotransferase
NQ562_01380	COG0489	protein tyrosine kinase activity
NQ562_01390	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
NQ562_01400	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NQ562_01405	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NQ562_01410	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NQ562_01415	COG0077	Prephenate dehydratase
NQ562_01415	COG1605	Chorismate mutase
NQ562_01425	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NQ562_01430	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NQ562_01440	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NQ562_01450	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
NQ562_01450	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
NQ562_01455	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
NQ562_01465	COG0583	DNA-binding transcription factor activity
NQ562_01470	COG0028	Belongs to the TPP enzyme family
NQ562_01490	COG0542	response to heat
NQ562_01500	COG0710	3-dehydroquinate dehydratase activity
NQ562_01505	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NQ562_01510	COG0668	transmembrane transport
NQ562_01515	COG2379	hydroxypyruvate reductase
NQ562_01555	COG2358	TRAP transporter, solute receptor (TAXI family
NQ562_01610	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NQ562_01640	COG3189	MarR family transcriptional regulator
NQ562_01650	COG1115	amino acid carrier protein
NQ562_01655	COG0544	peptidyl-prolyl cis-trans isomerase activity
NQ562_01660	COG0740	serine-type endopeptidase activity
NQ562_01665	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NQ562_01670	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NQ562_01680	COG0494	nUDIX hydrolase
NQ562_01685	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NQ562_01700	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NQ562_01705	COG2860	membrane
NQ562_01715	COG1666	GTP binding
NQ562_01725	COG0556	nucleotide-excision repair
NQ562_01735	COG0322	excinuclease ABC activity
NQ562_01740	COG1773	rubredoxin
NQ562_01745	COG0561	phosphatase activity
NQ562_01750	COG1660	Displays ATPase and GTPase activities
NQ562_01755	COG0391	Required for morphogenesis under gluconeogenic growth conditions
NQ562_01805	COG2610	gluconate transmembrane transporter activity
NQ562_01810	COG0396	ATPase activity
NQ562_01815	COG0719	Fe-S assembly protein
NQ562_01825	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NQ562_01830	COG0822	iron-sulfur transferase activity
NQ562_01835	COG1185	polyribonucleotide nucleotidyltransferase activity
NQ562_01840	COG1263	PTS System
NQ562_01840	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NQ562_01840	COG2190	(PTS) system
NQ562_01850	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NQ562_01855	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NQ562_01865	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NQ562_01875	COG0351	phosphomethylpyrimidine kinase
NQ562_01880	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NQ562_01885	COG0352	thiamine-phosphate diphosphorylase activity
NQ562_01895	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NQ562_01900	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NQ562_01905	COG0228	four-way junction DNA binding
NQ562_01920	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NQ562_01925	COG0336	Belongs to the RNA methyltransferase TrmD family
NQ562_01930	COG0335	large ribosomal subunit rRNA binding
NQ562_01940	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NQ562_01950	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NQ562_01955	COG0792	nuclease activity
NQ562_01985	COG0572	uridine kinase
NQ562_01990	COG0436	Aminotransferase
NQ562_02005	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NQ562_02015	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NQ562_02020	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NQ562_02045	COG1122	ATPase activity
NQ562_02055	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NQ562_02060	COG0101	tRNA pseudouridine synthase activity
NQ562_02065	COG4771	TonB-dependent receptor
NQ562_02075	COG1121	(ABC) transporter
NQ562_02080	COG0811	peptide transport
NQ562_02105	COG1268	BioY protein
NQ562_02110	COG0183	Belongs to the thiolase family
NQ562_02130	COG1720	tRNA m6t6A37 methyltransferase activity
NQ562_02150	COG2731	YhcH YjgK YiaL family protein
NQ562_02185	COG0583	DNA-binding transcription factor activity
NQ562_02190	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NQ562_02195	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NQ562_02205	COG0602	queuosine metabolic process
NQ562_02225	COG4948	Mandelate Racemase Muconate Lactonizing
NQ562_02245	COG3584	3D domain protein
NQ562_02245	COG1388	LysM domain
NQ562_02255	COG1960	acyl-CoA dehydrogenase activity
NQ562_02265	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NQ562_02275	COG1214	PFAM Peptidase M22, glycoprotease
NQ562_02290	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NQ562_02295	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NQ562_02305	COG1979	alcohol dehydrogenase
NQ562_02310	COG0426	domain, Protein
NQ562_02355	COG0024	Methionine aminopeptidase
NQ562_02370	COG2252	PERMEase
NQ562_02375	COG0037	tRNA processing
NQ562_02385	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NQ562_02400	COG1966	Carbon starvation protein
NQ562_02405	COG0039	L-malate dehydrogenase activity
NQ562_02410	COG0179	Fumarylacetoacetate (FAA) hydrolase
NQ562_02420	COG3875	lactate racemase activity
NQ562_02535	COG3843	relaxase mobilization nuclease domain protein
NQ562_02555	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NQ562_02590	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NQ562_02595	COG1702	phosphate starvation-inducible protein PhoH
NQ562_02600	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NQ562_02610	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NQ562_02615	COG1253	flavin adenine dinucleotide binding
NQ562_02630	COG0708	Exodeoxyribonuclease III
NQ562_02640	COG0494	nUDIX hydrolase
NQ562_02650	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NQ562_02660	COG0495	leucyl-tRNA aminoacylation
NQ562_02665	COG1555	photosystem II stabilization
NQ562_02665	COG1596	polysaccharide export
NQ562_02670	COG2333	competence protein COMEC
NQ562_02670	COG0658	competence protein
NQ562_02680	COG0786	glutamate:sodium symporter activity
NQ562_02690	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NQ562_02695	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NQ562_02700	COG1802	Transcriptional regulator
NQ562_02705	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NQ562_02710	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NQ562_02715	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NQ562_02730	COG1760	l-serine dehydratase
NQ562_02735	COG1760	l-serine dehydratase
NQ562_02740	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
NQ562_02750	COG0254	rRNA binding
NQ562_02755	COG3872	metal-dependent enzyme
NQ562_02760	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NQ562_02765	COG2890	protein-(glutamine-N5) methyltransferase activity
NQ562_02770	COG0009	L-threonylcarbamoyladenylate synthase
NQ562_02775	COG0698	ribose 5-phosphate isomerase
NQ562_02780	COG4475	Protein of unknown function (DUF436)
NQ562_02785	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NQ562_02790	COG2131	deaminase
NQ562_02805	COG0473	3-isopropylmalate dehydrogenase activity
NQ562_02825	COG0589	response to stress
NQ562_02830	COG0589	response to stress
NQ562_02835	COG0589	response to stress
NQ562_02840	COG0589	response to stress
NQ562_02845	COG0525	valine-tRNA ligase activity
NQ562_02850	COG0285	dihydrofolate synthase activity
NQ562_02870	COG3052	prosthetic group binding
NQ562_02875	COG0583	DNA-binding transcription factor activity
NQ562_02885	COG2851	Citrate transporter
NQ562_02905	COG2801	Transposase and inactivated derivatives
NQ562_02915	COG1177	transmembrane transport
NQ562_02920	COG1176	ABC-type spermidine putrescine transport system, permease component I
NQ562_02940	COG1733	regulation of RNA biosynthetic process
NQ562_02945	COG2195	Cleaves the N-terminal amino acid of tripeptides
NQ562_02965	COG1288	antiporter activity
NQ562_02970	COG2195	Cleaves the N-terminal amino acid of tripeptides
NQ562_02975	COG0583	DNA-binding transcription factor activity
NQ562_02985	COG2706	6-phosphogluconolactonase activity
NQ562_02995	COG0583	DNA-binding transcription factor activity
NQ562_03005	COG0778	Nitroreductase
NQ562_03020	COG0583	DNA-binding transcription factor activity
NQ562_03030	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NQ562_03035	COG1846	Transcriptional regulator
NQ562_03045	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NQ562_03060	COG2195	Cleaves the N-terminal amino acid of tripeptides
NQ562_03065	COG1304	FMN binding
NQ562_03075	COG3314	Sporulation integral membrane protein YlbJ
NQ562_03080	COG1414	Transcriptional regulator
NQ562_03085	COG3314	Sporulation integral membrane protein YlbJ
NQ562_03095	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NQ562_03095	COG0674	pyruvate-flavodoxin oxidoreductase activity
NQ562_03115	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NQ562_03120	COG1132	(ABC) transporter
NQ562_03125	COG1663	tetraacyldisaccharide 4'-kinase activity
NQ562_03130	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
NQ562_03135	COG2877	3-deoxy-8-phosphooctulonate synthase activity
NQ562_03145	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NQ562_03165	COG1137	ATPase activity
NQ562_03175	COG4443	Transcriptional Coactivator p15 (PC4)
NQ562_03180	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NQ562_03190	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NQ562_03190	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
NQ562_03195	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NQ562_03200	COG1490	D-aminoacyl-tRNA deacylase activity
NQ562_03210	COG0628	permease
NQ562_03215	COG0124	histidyl-tRNA synthetase
NQ562_03220	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NQ562_03230	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NQ562_03235	COG0564	pseudouridine synthase activity
NQ562_03240	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NQ562_03245	COG1196	nuclear chromosome segregation
NQ562_03250	COG0552	protein localization to endoplasmic reticulum
NQ562_03255	COG3118	belongs to the thioredoxin family
NQ562_03265	COG2968	Membrane
NQ562_03270	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NQ562_03280	COG3468	outer membrane autotransporter barrel domain protein
NQ562_03345	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NQ562_03350	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
NQ562_03360	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NQ562_03365	COG0640	Transcriptional regulator
NQ562_03385	COG2814	Major facilitator Superfamily
NQ562_03400	COG2226	methyltransferase
NQ562_03405	COG1191	sigma factor activity
NQ562_03435	COG1484	DNA-dependent DNA replication
NQ562_03450	COG2814	Major facilitator Superfamily
NQ562_03465	COG1846	Transcriptional regulator
NQ562_03470	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NQ562_03480	COG2848	UPF0210 protein
NQ562_03485	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NQ562_03500	COG2207	Transcriptional regulator
NQ562_03520	COG1115	amino acid carrier protein
NQ562_03525	COG1473	amidohydrolase
NQ562_03535	COG0183	Belongs to the thiolase family
NQ562_03545	COG1250	3-hydroxyacyl-CoA dehydrogenase
NQ562_03550	COG1024	Enoyl-CoA hydratase
NQ562_03555	COG1362	aminopeptidase activity
NQ562_03560	COG1012	belongs to the aldehyde dehydrogenase family
NQ562_03570	COG1739	Uncharacterized protein family UPF0029
NQ562_03585	COG2990	Protein conserved in bacteria
NQ562_03595	COG0497	DNA recombination
NQ562_03600	COG0497	DNA recombination
NQ562_03610	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
NQ562_03615	COG2964	Protein conserved in bacteria
NQ562_03630	COG0488	(ABC) transporter
NQ562_03670	COG1592	Rubrerythrin
NQ562_03685	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NQ562_03685	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NQ562_03700	COG0217	transcriptional regulatory protein
NQ562_03705	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NQ562_03710	COG0632	four-way junction helicase activity
NQ562_03715	COG2255	four-way junction helicase activity
NQ562_03720	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NQ562_03725	COG2385	sporulation resulting in formation of a cellular spore
NQ562_03730	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NQ562_03740	COG1862	Preprotein translocase
NQ562_03750	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NQ562_03755	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NQ562_03800	COG1253	flavin adenine dinucleotide binding
NQ562_03820	COG3326	Membrane
NQ562_03830	COG2086	electron transfer activity
NQ562_03875	COG2264	protein methyltransferase activity
NQ562_03880	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NQ562_03885	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NQ562_03890	COG0537	adenosine 5'-monophosphoramidase activity
NQ562_03900	COG1610	YqeY-like protein
NQ562_03935	COG0450	alkyl hydroperoxide reductase
NQ562_03955	COG0742	ribosomal rna small subunit methyltransferase
NQ562_03960	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NQ562_03975	COG1323	Belongs to the UPF0348 family
NQ562_03980	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NQ562_03990	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NQ562_03995	COG2030	dehydratase
NQ562_04000	COG0416	fatty acid biosynthetic process
NQ562_04005	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NQ562_04010	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NQ562_04015	COG1028	Short-chain dehydrogenase reductase Sdr
NQ562_04020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NQ562_04030	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NQ562_04035	COG0571	ribonuclease III activity
NQ562_04050	COG0052	Belongs to the universal ribosomal protein uS2 family
NQ562_04055	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NQ562_04060	COG0528	UMP kinase activity
NQ562_04065	COG0233	cytoplasmic translational termination
NQ562_04080	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NQ562_04085	COG0575	Belongs to the CDS family
NQ562_04090	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NQ562_04095	COG0750	zinc metalloprotease
NQ562_04100	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NQ562_04105	COG0442	prolyl-tRNA aminoacylation
NQ562_04110	COG1285	pathogenesis
NQ562_04125	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
NQ562_04130	COG1217	gtp-binding protein TYPA
NQ562_04145	COG0779	Required for maturation of 30S ribosomal subunits
NQ562_04150	COG0195	Participates in both transcription termination and antitermination
NQ562_04155	COG2740	Nucleic-acid-binding protein implicated in transcription termination
NQ562_04160	COG1358	cellular component organization or biogenesis
NQ562_04165	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NQ562_04165	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NQ562_04170	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NQ562_04175	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NQ562_04180	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NQ562_04185	COG0196	riboflavin kinase activity
NQ562_04195	COG1473	amidohydrolase
NQ562_04205	COG1120	ATPase activity
NQ562_04210	COG0390	transport system, permease component
NQ562_04215	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NQ562_04225	COG0583	DNA-binding transcription factor activity
NQ562_04230	COG4948	Mandelate Racemase Muconate Lactonizing
NQ562_04235	COG2610	gluconate transmembrane transporter activity
NQ562_04240	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NQ562_04250	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NQ562_04250	COG0674	pyruvate-flavodoxin oxidoreductase activity
NQ562_04255	COG1013	pyruvate-flavodoxin oxidoreductase activity
NQ562_04265	COG0129	dihydroxy-acid dehydratase activity
NQ562_04280	COG0427	acetyl-CoA hydrolase
NQ562_04285	COG0655	NAD(P)H dehydrogenase (quinone) activity
NQ562_04295	COG0534	Mate efflux family protein
NQ562_04315	COG0622	Phosphoesterase
NQ562_04325	COG2079	MmgE PrpD family protein
NQ562_04330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NQ562_04335	COG0765	amino acid transport
NQ562_04340	COG0765	amino acid transport
NQ562_04345	COG1126	abc transporter atp-binding protein
NQ562_04350	COG0456	acetyltransferase
NQ562_04360	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NQ562_04375	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NQ562_04380	COG2721	sulfolactate sulfo-lyase activity
NQ562_04395	COG2001	Belongs to the MraZ family
NQ562_04400	COG0275	rRNA processing
NQ562_04405	COG4839	cell division protein FtsL
NQ562_04415	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NQ562_04420	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NQ562_04425	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NQ562_04430	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NQ562_04435	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NQ562_04440	COG1181	Belongs to the D-alanine--D-alanine ligase family
NQ562_04455	COG3856	small basic protein
NQ562_04460	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NQ562_04465	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NQ562_04480	COG2165	general secretion pathway protein
NQ562_04510	COG2801	Transposase and inactivated derivatives
NQ562_04530	COG1561	YicC-like family, N-terminal region
NQ562_04535	COG2052	Domain of unknown function (DUF370)
NQ562_04540	COG0194	GDP metabolic process
NQ562_04545	COG1758	RNA polymerase activity
NQ562_04550	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NQ562_04570	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NQ562_04600	COG0697	spore germination
NQ562_04630	COG0733	neurotransmitter:sodium symporter activity
NQ562_04640	COG1741	Belongs to the pirin family
NQ562_04645	COG1301	dicarboxylic acid transport
NQ562_04660	COG0149	triose-phosphate isomerase activity
NQ562_04660	COG0126	phosphoglycerate kinase activity
NQ562_04675	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NQ562_04690	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NQ562_04700	COG0346	lactoylglutathione lyase activity
NQ562_04705	COG0640	Transcriptional regulator
NQ562_04710	COG0583	DNA-binding transcription factor activity
NQ562_04745	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NQ562_04750	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NQ562_04760	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NQ562_04765	COG0720	synthase
NQ562_04780	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NQ562_04780	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NQ562_04810	COG0519	Catalyzes the synthesis of GMP from XMP
NQ562_04825	COG0667	Aldo Keto reductase
NQ562_04830	COG1131	(ABC) transporter
NQ562_04855	COG0667	Aldo Keto reductase
NQ562_04875	COG2814	Major facilitator Superfamily
NQ562_04895	COG1342	Belongs to the UPF0251 family
NQ562_04910	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NQ562_04925	COG1105	Belongs to the carbohydrate kinase PfkB family
NQ562_04930	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NQ562_04930	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NQ562_04930	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NQ562_04935	COG2801	Transposase and inactivated derivatives
NQ562_04975	COG1115	amino acid carrier protein
NQ562_04980	COG2040	homocysteine
NQ562_04985	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NQ562_05010	COG2217	Heavy metal translocating P-type atpase
NQ562_05015	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NQ562_05020	COG1773	rubredoxin
NQ562_05020	COG1592	Rubrerythrin
NQ562_05025	COG0745	RESPONSE REGULATOR receiver
NQ562_05030	COG5002	protein histidine kinase activity
NQ562_05030	COG3850	Histidine kinase
NQ562_05040	COG3679	Belongs to the UPF0342 family
NQ562_05045	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NQ562_05050	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
NQ562_05055	COG1074	ATP-dependent DNA helicase activity
NQ562_05060	COG0583	DNA-binding transcription factor activity
NQ562_05075	COG0583	DNA-binding transcription factor activity
NQ562_05085	COG1301	dicarboxylic acid transport
NQ562_05095	COG3344	reverse transcriptase
NQ562_05105	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NQ562_05115	COG0251	oxidation-reduction process
NQ562_05120	COG0604	alcohol dehydrogenase
NQ562_05130	COG1250	3-hydroxyacyl-CoA dehydrogenase
NQ562_05135	COG0385	Bile acid
NQ562_05140	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NQ562_05145	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NQ562_05210	COG5377	YqaJ viral recombinase family
NQ562_05215	COG3723	Recombinational DNA repair protein, rece pathway
NQ562_05235	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
NQ562_05270	COG1783	phage Terminase large subunit
NQ562_05440	COG0557	exoribonuclease II activity
NQ562_05445	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NQ562_05450	COG2033	superoxide reductase activity
NQ562_05455	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NQ562_05460	COG0583	DNA-binding transcription factor activity
NQ562_05475	COG0473	3-isopropylmalate dehydrogenase activity
NQ562_05480	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NQ562_05485	COG0436	Aminotransferase
NQ562_05510	COG3906	Belongs to the UPF0473 family
NQ562_05515	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NQ562_05520	COG0826	peptidase U32
NQ562_05525	COG0006	proline dipeptidase activity
NQ562_05530	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NQ562_05550	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NQ562_05560	COG1489	DNA binding
NQ562_05565	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NQ562_05570	COG0758	DNA mediated transformation
NQ562_05575	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NQ562_05580	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NQ562_05585	COG4974	Belongs to the 'phage' integrase family
NQ562_05595	COG1994	Peptidase M50
NQ562_05605	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NQ562_05610	COG1187	pseudouridine synthase activity
NQ562_05615	COG2081	HI0933 family
NQ562_05620	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NQ562_05630	COG0539	negative regulation of cytoplasmic translation
NQ562_05630	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NQ562_05640	COG1160	GTP binding
NQ562_05645	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
NQ562_05655	COG4492	Belongs to the UPF0735 family
NQ562_05660	COG0460	homoserine dehydrogenase
NQ562_05665	COG0083	homoserine kinase activity
NQ562_05675	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NQ562_05685	COG0688	phosphatidylethanolamine metabolic process
NQ562_05710	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NQ562_05720	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NQ562_05725	COG0402	S-adenosylhomocysteine deaminase activity
NQ562_05735	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NQ562_05745	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
NQ562_05750	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NQ562_05755	COG0513	Belongs to the DEAD box helicase family
NQ562_05760	COG1058	Belongs to the CinA family
NQ562_05760	COG1546	Belongs to the CinA family
NQ562_05765	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NQ562_05770	COG1426	Protein conserved in bacteria
NQ562_05775	COG1674	ftsk spoiiie
NQ562_05780	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NQ562_05790	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NQ562_05800	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NQ562_05810	COG0613	PHP domain protein
NQ562_05815	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NQ562_05820	COG0527	aspartate kinase activity
NQ562_05825	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NQ562_05830	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NQ562_05840	COG0756	dUTP diphosphatase activity
NQ562_05850	COG0564	pseudouridine synthase activity
NQ562_05855	COG0191	fructose-bisphosphate aldolase activity
NQ562_05885	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NQ562_05890	COG1116	anion transmembrane transporter activity
NQ562_05905	COG2359	stage V sporulation protein S
NQ562_05910	COG0494	nUDIX hydrolase
NQ562_05915	COG0497	DNA recombination
NQ562_05925	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NQ562_05930	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
NQ562_05935	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NQ562_05945	COG1722	exodeoxyribonuclease VII activity
NQ562_05950	COG1570	exodeoxyribonuclease VII activity
NQ562_05955	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NQ562_05960	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NQ562_05980	COG0786	glutamate:sodium symporter activity
NQ562_05990	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NQ562_05995	COG3426	butyrate kinase activity
NQ562_06005	COG0280	phosphate acetyltransferase
NQ562_06010	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NQ562_06020	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NQ562_06020	COG1013	pyruvate-flavodoxin oxidoreductase activity
NQ562_06020	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NQ562_06020	COG0674	pyruvate-flavodoxin oxidoreductase activity
NQ562_06035	COG0511	ligase activity, forming carbon-carbon bonds
NQ562_06035	COG5016	pyruvate
NQ562_06065	COG2357	RelA SpoT domain protein
NQ562_06080	COG0517	IMP dehydrogenase activity
NQ562_06080	COG0516	GMP reductase activity
NQ562_06085	COG0151	Belongs to the GarS family
NQ562_06090	COG0138	bifunctional purine biosynthesis protein purh
NQ562_06095	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NQ562_06100	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NQ562_06105	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NQ562_06110	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NQ562_06115	COG0534	Mate efflux family protein
NQ562_06125	COG2852	Protein conserved in bacteria
NQ562_06130	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
NQ562_06135	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
NQ562_06140	COG1687	branched-chain amino acid
NQ562_06145	COG0704	Plays a role in the regulation of phosphate uptake
NQ562_06150	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NQ562_06155	COG0581	inorganic phosphate transmembrane transporter activity
NQ562_06160	COG0573	inorganic phosphate transmembrane transporter activity
NQ562_06165	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NQ562_06175	COG0656	L-ascorbic acid biosynthetic process
NQ562_06190	COG4175	Glycine betaine
NQ562_06190	COG0517	IMP dehydrogenase activity
NQ562_06195	COG4176	ABC-type proline glycine betaine transport system permease component
NQ562_06205	COG1228	amidohydrolase
NQ562_06215	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
NQ562_06230	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NQ562_06235	COG0459	protein refolding
NQ562_06240	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NQ562_06250	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NQ562_06260	COG3584	3D domain protein
NQ562_06260	COG1388	LysM domain
NQ562_06265	COG0084	hydrolase, TatD family'
NQ562_06270	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NQ562_06270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NQ562_06275	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NQ562_06280	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NQ562_06285	COG1774	PSP1 C-terminal conserved region
NQ562_06295	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NQ562_06300	COG1982	Orn Lys Arg decarboxylase major
NQ562_06310	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NQ562_06315	COG0284	orotidine-5'-phosphate decarboxylase activity
NQ562_06320	COG0167	dihydroorotate dehydrogenase activity
NQ562_06325	COG0543	2 iron, 2 sulfur cluster binding
NQ562_06330	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NQ562_06335	COG0505	Belongs to the CarA family
NQ562_06340	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NQ562_06345	COG0540	Belongs to the ATCase OTCase family
NQ562_06350	COG2852	Protein conserved in bacteria
NQ562_06355	COG2852	Protein conserved in bacteria
NQ562_06375	COG2801	Transposase and inactivated derivatives
NQ562_06380	COG1309	transcriptional regulator
NQ562_06400	COG1216	Glycosyl transferase, family 2
NQ562_06415	COG1088	dTDP-glucose 4,6-dehydratase activity
NQ562_06420	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
NQ562_06425	COG1216	Glycosyl transferase, family 2
NQ562_06440	COG1088	dTDP-glucose 4,6-dehydratase activity
NQ562_06475	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NQ562_06480	COG3475	LICD family
NQ562_06490	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NQ562_06495	COG3475	LICD family
NQ562_06510	COG0562	UDP-galactopyranose mutase
NQ562_06515	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NQ562_06525	COG0072	phenylalanine-tRNA ligase activity
NQ562_06525	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NQ562_06530	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NQ562_06575	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NQ562_06580	COG1518	maintenance of DNA repeat elements
NQ562_06585	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NQ562_06600	COG1917	Cupin 2, conserved barrel domain protein
NQ562_06600	COG4977	sequence-specific DNA binding
NQ562_06615	COG0463	Glycosyl transferase, family 2
NQ562_06620	COG0492	ferredoxin-NADP+ reductase activity
NQ562_06620	COG3118	belongs to the thioredoxin family
NQ562_06635	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NQ562_06645	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NQ562_06660	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NQ562_06665	COG0215	cysteine-tRNA ligase activity
NQ562_06670	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NQ562_06670	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
NQ562_06675	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NQ562_06675	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NQ562_06680	COG4956	integral membrane protein (PIN domain superfamily)
NQ562_06695	COG3481	metal-dependent phosphohydrolase, HD sub domain
NQ562_06700	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NQ562_06710	COG0515	serine threonine protein kinase
NQ562_06720	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NQ562_06735	COG0501	Belongs to the peptidase M48B family
NQ562_06745	COG4974	Belongs to the 'phage' integrase family
NQ562_06750	COG1923	regulation of RNA biosynthetic process
NQ562_06755	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NQ562_06765	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NQ562_06770	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NQ562_06775	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NQ562_06790	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NQ562_06800	COG0138	bifunctional purine biosynthesis protein purh
NQ562_06805	COG0484	heat shock protein binding
NQ562_06810	COG0443	Heat shock 70 kDa protein
NQ562_06815	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NQ562_06825	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NQ562_06840	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
NQ562_06845	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
NQ562_06850	COG3273	potassium ion transport
NQ562_06850	COG0471	metal ion transport
NQ562_06860	COG0481	GTPase activity
NQ562_06865	COG0268	Binds directly to 16S ribosomal RNA
NQ562_06870	COG1193	negative regulation of DNA recombination
NQ562_06875	COG0826	peptidase U32
NQ562_06880	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NQ562_06885	COG0494	nUDIX hydrolase
NQ562_06890	COG0427	acetyl-CoA hydrolase
NQ562_06895	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NQ562_06900	COG1970	mechanosensitive ion channel activity
NQ562_06905	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NQ562_06910	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NQ562_06915	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NQ562_06920	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NQ562_06935	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NQ562_06940	COG0140	phosphoribosyl-ATP diphosphatase activity
NQ562_06940	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NQ562_06945	COG0107	imidazoleglycerol-phosphate synthase activity
NQ562_06955	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NQ562_06960	COG0131	Imidazoleglycerol-phosphate dehydratase
NQ562_06965	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NQ562_06980	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NQ562_06985	COG4496	protein, YerC YecD
NQ562_06990	COG2011	ABC-type metal ion transport system permease component
NQ562_06995	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NQ562_07005	COG1785	Belongs to the alkaline phosphatase family
NQ562_07015	COG1136	(ABC) transporter
NQ562_07030	COG1823	symporter activity
NQ562_07035	COG0786	glutamate:sodium symporter activity
NQ562_07040	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NQ562_07040	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NQ562_07050	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NQ562_07090	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NQ562_07095	COG1362	aminopeptidase activity
NQ562_07100	COG0531	amino acid
NQ562_07105	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NQ562_07110	COG1464	Belongs to the NlpA lipoprotein family
NQ562_07140	COG1196	nuclear chromosome segregation
NQ562_07155	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NQ562_07160	COG1799	cell septum assembly
NQ562_07165	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NQ562_07170	COG1496	oxidoreductase activity
NQ562_07185	COG4372	Transposase
NQ562_07190	COG4443	Transcriptional Coactivator p15 (PC4)
NQ562_07200	COG0859	PFAM glycosyl transferase family 9
NQ562_07205	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NQ562_07210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NQ562_07215	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NQ562_07215	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NQ562_07220	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
NQ562_07245	COG1937	Protein conserved in bacteria
NQ562_07250	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NQ562_07255	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NQ562_07260	COG0569	domain protein
NQ562_07265	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NQ562_07270	COG1304	FMN binding
NQ562_07275	COG1733	regulation of RNA biosynthetic process
NQ562_07280	COG3384	dioxygenase
NQ562_07305	COG0726	polysaccharide deacetylase
NQ562_07320	COG2203	Gaf domain
NQ562_07320	COG3706	GGDEF domain
NQ562_07320	COG4251	negative regulation of phosphorylation
NQ562_07320	COG5001	Diguanylate cyclase
NQ562_07350	COG4771	TonB-dependent receptor
NQ562_07375	COG0811	peptide transport
NQ562_07380	COG1132	(ABC) transporter
NQ562_07385	COG1120	ATPase activity
NQ562_07390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NQ562_07395	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NQ562_07400	COG4771	TonB-dependent receptor
NQ562_07425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NQ562_07435	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
NQ562_07435	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
NQ562_07440	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NQ562_07450	COG0037	tRNA processing
NQ562_07455	COG1098	S1 RNA binding domain
NQ562_07465	COG0776	regulation of translation
NQ562_07470	COG3956	TIGRFAM MazG family protein
NQ562_07475	COG2244	polysaccharide biosynthetic process
NQ562_07480	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NQ562_07485	COG1494	fructose-1,6-bisphosphatase
NQ562_07490	COG0504	CTP synthase activity
NQ562_07495	COG0018	arginyl-trna synthetase
NQ562_07505	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NQ562_07520	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NQ562_07520	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NQ562_07525	COG0736	holo-[acyl-carrier-protein] synthase activity
NQ562_07530	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NQ562_07555	COG4120	Belongs to the binding-protein-dependent transport system permease family
NQ562_07570	COG0501	Belongs to the peptidase M48B family
NQ562_07585	COG0419	ATPase involved in DNA repair
NQ562_07600	COG2205	protein histidine kinase activity
NQ562_07605	COG0745	RESPONSE REGULATOR receiver
NQ562_07620	COG2239	Acts as a magnesium transporter
NQ562_07630	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NQ562_07635	COG0534	Mate efflux family protein
NQ562_07645	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NQ562_07650	COG1464	Belongs to the NlpA lipoprotein family
NQ562_07655	COG0281	malic enzyme
NQ562_07665	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NQ562_07680	COG0824	Thioesterase
NQ562_07690	COG3859	Proton-coupled thiamine transporter YuaJ
NQ562_07695	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NQ562_07700	COG0784	Response regulator, receiver
NQ562_07700	COG2198	Histidine kinase
NQ562_07700	COG2205	protein histidine kinase activity
NQ562_07705	COG0793	Belongs to the peptidase S41A family
NQ562_07705	COG3409	Peptidoglycan-binding domain 1 protein
NQ562_07715	COG2177	Part of the ABC transporter FtsEX involved in
NQ562_07720	COG2884	Cell division ATP-binding protein ftsE
NQ562_07735	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NQ562_07740	COG0653	protein targeting
NQ562_07745	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NQ562_07755	COG0765	amino acid transport
NQ562_07760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NQ562_07765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NQ562_07770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NQ562_07775	COG0784	Response regulator, receiver
NQ562_07775	COG3437	response regulator, receiver
NQ562_07785	COG0519	Catalyzes the synthesis of GMP from XMP
NQ562_07815	COG0583	DNA-binding transcription factor activity
NQ562_07830	COG0583	DNA-binding transcription factor activity
NQ562_07840	COG0300	oxidoreductase activity
NQ562_07845	COG1028	Short-chain dehydrogenase reductase Sdr
NQ562_07850	COG1073	alpha beta
NQ562_07855	COG2272	Belongs to the type-B carboxylesterase lipase family
NQ562_07860	COG1979	alcohol dehydrogenase
NQ562_07905	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NQ562_07910	COG1827	regulation of RNA biosynthetic process
NQ562_07930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NQ562_07945	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NQ562_07955	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
NQ562_07960	COG1560	Kdo2-lipid A biosynthetic process
NQ562_07990	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NQ562_08010	COG1127	ABC transporter
NQ562_08015	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NQ562_08035	COG1077	Cell shape determining protein MreB Mrl
NQ562_08040	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NQ562_08065	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NQ562_08070	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NQ562_08075	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NQ562_08075	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NQ562_08080	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NQ562_08085	COG0356	it plays a direct role in the translocation of protons across the membrane
NQ562_08095	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
NQ562_08100	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NQ562_08120	COG0534	Mate efflux family protein
NQ562_08130	COG1597	lipid kinase activity
NQ562_08145	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NQ562_08150	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NQ562_08155	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NQ562_08170	COG0277	FAD linked oxidase domain protein
NQ562_08175	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NQ562_08180	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
NQ562_08185	COG0590	tRNA wobble adenosine to inosine editing
NQ562_08195	COG0583	DNA-binding transcription factor activity
NQ562_08200	COG2059	Chromate
NQ562_08235	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NQ562_08240	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NQ562_08245	COG1028	Short-chain dehydrogenase reductase Sdr
NQ562_08250	COG0456	acetyltransferase
NQ562_08250	COG1846	Transcriptional regulator
NQ562_08260	COG0456	acetyltransferase
NQ562_08310	COG2367	Beta-lactamase
NQ562_08340	COG0860	N-Acetylmuramoyl-L-alanine amidase
NQ562_08375	COG5301	cellulose 1,4-beta-cellobiosidase activity
NQ562_08385	COG3299	homolog of phage Mu protein gp47
NQ562_08465	COG0740	serine-type endopeptidase activity
NQ562_08480	COG4695	Portal protein
NQ562_08580	COG3645	SOS response
NQ562_08580	COG3646	Phage regulatory protein
NQ562_08645	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NQ562_08650	COG1733	regulation of RNA biosynthetic process
NQ562_08655	COG2910	NAD(P)H-binding
NQ562_08690	COG1979	alcohol dehydrogenase
NQ562_08695	COG3829	transcription factor binding
NQ562_08705	COG2207	Transcriptional regulator
NQ562_08715	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NQ562_08720	COG1882	Formate acetyltransferase
NQ562_08740	COG1115	amino acid carrier protein
NQ562_08750	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NQ562_08750	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NQ562_08750	COG0674	pyruvate-flavodoxin oxidoreductase activity
NQ562_08750	COG1013	pyruvate-flavodoxin oxidoreductase activity
NQ562_08765	COG0493	'glutamate synthase
NQ562_08765	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
NQ562_08785	COG5002	protein histidine kinase activity
NQ562_08790	COG0745	RESPONSE REGULATOR receiver
NQ562_08795	COG0280	phosphate acetyltransferase
NQ562_08825	COG1301	dicarboxylic acid transport
NQ562_08830	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NQ562_08835	COG0251	oxidation-reduction process
NQ562_08905	COG1061	Type III restriction enzyme res subunit
NQ562_08910	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NQ562_08915	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NQ562_08920	COG3858	chitin binding
NQ562_08925	COG1227	inorganic diphosphatase activity
NQ562_08930	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
NQ562_08940	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NQ562_08945	COG1473	amidohydrolase
NQ562_08955	COG0165	Argininosuccinate lyase
NQ562_08965	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NQ562_08970	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NQ562_08975	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NQ562_08980	COG4499	WXG100 protein secretion system (Wss), protein YukC
NQ562_08980	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NQ562_08985	COG0166	Belongs to the GPI family
NQ562_08995	COG2801	Transposase and inactivated derivatives
NQ562_09030	COG0741	lytic transglycosylase activity
NQ562_09035	COG0237	dephospho-CoA kinase activity
NQ562_09040	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NQ562_09050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NQ562_09060	COG1115	amino acid carrier protein
NQ562_09065	COG1757	Na H antiporter
NQ562_09070	COG0798	PFAM Bile acid sodium symporter
NQ562_09095	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NQ562_09100	COG2022	thiamine diphosphate biosynthetic process
NQ562_09110	COG0352	thiamine-phosphate diphosphorylase activity
NQ562_09120	COG0583	DNA-binding transcription factor activity
NQ562_09150	COG0583	DNA-binding transcription factor activity
NQ562_09155	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
NQ562_09160	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
NQ562_09160	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
NQ562_09165	COG3964	amidohydrolase
NQ562_09190	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NQ562_09195	COG0490	domain, Protein
NQ562_09195	COG0471	metal ion transport
NQ562_09210	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
NQ562_09220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NQ562_09230	COG4771	TonB-dependent receptor
NQ562_09270	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
NQ562_09275	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
NQ562_09280	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
NQ562_09290	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NQ562_09295	COG0085	RNA polymerase activity
NQ562_09320	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NQ562_09325	COG0697	spore germination
NQ562_09330	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NQ562_09335	COG0154	amidase activity
NQ562_09340	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NQ562_09345	COG0626	cystathionine gamma-synthase activity
NQ562_09355	COG0751	glycine-tRNA ligase activity
NQ562_09360	COG0752	glycyl-tRNA synthetase alpha subunit
NQ562_09365	COG0531	amino acid
NQ562_09370	COG0463	Glycosyl transferase, family 2
NQ562_09385	COG1288	antiporter activity
NQ562_09390	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NQ562_09410	COG0358	DNA primase activity
NQ562_09420	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
NQ562_09425	COG0517	IMP dehydrogenase activity
NQ562_09430	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NQ562_09430	COG0574	Belongs to the PEP-utilizing enzyme family
NQ562_09435	COG3314	Sporulation integral membrane protein YlbJ
NQ562_09450	COG4139	cobalamin transport
NQ562_09460	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NQ562_09485	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NQ562_09500	COG1297	OPT oligopeptide transporter protein
NQ562_09505	COG0159	tryptophan synthase activity
NQ562_09510	COG0133	tryptophan synthase activity
NQ562_09515	COG0135	phosphoribosylanthranilate isomerase activity
NQ562_09555	COG2011	ABC-type metal ion transport system permease component
NQ562_09560	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NQ562_09580	COG0490	domain, Protein
NQ562_09580	COG2985	domain, Protein
NQ562_09595	COG2801	Transposase and inactivated derivatives
NQ562_09600	COG1473	amidohydrolase
NQ562_09605	COG3681	Belongs to the UPF0597 family
NQ562_09620	COG0222	ribosome binding
NQ562_09625	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NQ562_09630	COG0081	regulation of translation
NQ562_09635	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NQ562_09640	COG0250	Participates in transcription elongation, termination and antitermination
NQ562_09650	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NQ562_09655	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NQ562_09705	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NQ562_09710	COG0426	domain, Protein
NQ562_09715	COG1115	amino acid carrier protein
NQ562_09720	COG4178	(ABC) transporter
NQ562_09730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NQ562_09740	COG0277	FAD linked oxidase domain protein
NQ562_09745	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NQ562_09750	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NQ562_09755	COG0531	amino acid
NQ562_09760	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NQ562_09785	COG1335	isochorismatase
NQ562_09790	COG2195	Cleaves the N-terminal amino acid of tripeptides
NQ562_09805	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NQ562_09815	COG0248	Ppx GppA phosphatase
NQ562_09825	COG1346	cytolysis
NQ562_09835	COG1288	antiporter activity
NQ562_09840	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NQ562_09845	COG5599	Phosphatase
NQ562_09855	COG1959	2 iron, 2 sulfur cluster binding
NQ562_09865	COG0129	dihydroxy-acid dehydratase activity
NQ562_09910	COG1683	Conserved Protein
NQ562_09915	COG0534	Mate efflux family protein
NQ562_09965	COG1473	amidohydrolase
NQ562_09970	COG1288	antiporter activity
NQ562_09980	COG0583	DNA-binding transcription factor activity
NQ562_09990	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NQ562_10000	COG1196	nuclear chromosome segregation
NQ562_10010	COG2176	DNA-directed DNA polymerase activity
NQ562_10020	COG2996	Protein conserved in bacteria
NQ562_10025	COG0799	negative regulation of ribosome biogenesis
NQ562_10030	COG1316	TRANSCRIPTIONal
NQ562_10035	COG1713	HD superfamily hydrolase involved in NAD metabolism
NQ562_10045	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NQ562_10050	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NQ562_10055	COG0012	GTP binding
NQ562_10060	COG2239	Acts as a magnesium transporter
NQ562_10070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NQ562_10070	COG1263	PTS System
NQ562_10075	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NQ562_10080	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NQ562_10095	COG0203	ribosomal protein L17
NQ562_10100	COG0202	RNA polymerase activity
NQ562_10105	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NQ562_10115	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NQ562_10120	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NQ562_10130	COG0563	adenylate kinase activity
NQ562_10135	COG0201	protein transport
NQ562_10145	COG1841	ribosomal large subunit assembly
NQ562_10150	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NQ562_10155	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NQ562_10160	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NQ562_10165	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NQ562_10170	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NQ562_10175	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NQ562_10180	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NQ562_10190	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NQ562_10195	COG0255	Belongs to the universal ribosomal protein uL29 family
NQ562_10200	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NQ562_10205	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NQ562_10210	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NQ562_10215	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NQ562_10220	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NQ562_10225	COG0089	rRNA binding
NQ562_10230	COG0088	Forms part of the polypeptide exit tunnel
NQ562_10235	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NQ562_10240	COG0051	transcription antitermination factor activity, RNA binding
NQ562_10245	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NQ562_10255	COG0049	tRNA binding
NQ562_10260	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NQ562_10265	COG1358	cellular component organization or biogenesis
NQ562_10290	COG0488	(ABC) transporter
NQ562_10295	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NQ562_10315	COG0542	response to heat
NQ562_10345	COG1979	alcohol dehydrogenase
NQ562_10350	COG1012	belongs to the aldehyde dehydrogenase family
NQ562_10355	COG0640	Transcriptional regulator
NQ562_10365	COG1114	Component of the transport system for branched-chain amino acids
NQ562_10370	COG1028	Short-chain dehydrogenase reductase Sdr
NQ562_10375	COG1278	Cold shock
NQ562_10380	COG2827	Endonuclease containing a URI domain
NQ562_10385	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NQ562_10395	COG0492	ferredoxin-NADP+ reductase activity
NQ562_10400	COG0741	lytic transglycosylase activity
NQ562_10400	COG1196	nuclear chromosome segregation
NQ562_10400	COG0739	heme binding
NQ562_10405	COG0583	DNA-binding transcription factor activity
NQ562_10430	COG2244	polysaccharide biosynthetic process
NQ562_10435	COG1924	4 iron, 4 sulfur cluster binding
NQ562_10440	COG0071	Belongs to the small heat shock protein (HSP20) family
NQ562_10450	COG2873	o-acetylhomoserine
NQ562_10460	COG0519	Catalyzes the synthesis of GMP from XMP
NQ562_10475	COG1115	amino acid carrier protein
NQ562_10485	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NQ562_10505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NQ562_10515	COG2801	Transposase and inactivated derivatives
NQ562_10525	COG0534	Mate efflux family protein
NQ562_10535	COG0114	fumarate hydratase activity
NQ562_10545	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NQ562_10550	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NQ562_10555	COG0066	3-isopropylmalate dehydratase activity
NQ562_10580	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NQ562_10585	COG0305	Participates in initiation and elongation during chromosome replication
NQ562_10590	COG0359	binds to the 23S rRNA
NQ562_10595	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
NQ562_10610	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NQ562_10615	COG0039	L-malate dehydrogenase activity
NQ562_10620	COG2610	gluconate transmembrane transporter activity
NQ562_10630	COG1473	amidohydrolase
NQ562_10635	COG1160	GTP binding
NQ562_10640	COG1160	GTP binding
NQ562_10650	COG0252	asparaginase activity
NQ562_10655	COG0156	8-amino-7-oxononanoate synthase activity
NQ562_10680	COG0745	RESPONSE REGULATOR receiver
NQ562_10690	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NQ562_10695	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NQ562_10700	COG0497	DNA recombination
NQ562_10720	COG1475	DNA binding
NQ562_10725	COG1192	Involved in chromosome partitioning
NQ562_10730	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NQ562_10735	COG1464	Belongs to the NlpA lipoprotein family
NQ562_10755	COG0357	Ribosomal RNA small subunit methyltransferase G
NQ562_10760	COG0445	tRNA wobble uridine modification
NQ562_10765	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NQ562_10770	COG1847	R3H domain protein
NQ562_10775	COG0706	membrane insertase activity
NQ562_10780	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NQ562_10785	COG0594	ribonuclease P activity
NQ562_10790	COG0230	Belongs to the bacterial ribosomal protein bL34 family
NQ562_10795	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NQ562_10800	COG2194	sulfuric ester hydrolase activity
NQ562_10810	COG1115	amino acid carrier protein
NQ562_10815	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NQ562_10835	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NQ562_10840	COG0823	Involved in the tonB-independent uptake of proteins
NQ562_10840	COG1506	peptidase
NQ562_10840	COG4946	Tricorn protease homolog