DFR85_01290 7d8181f05071bf7b328a46fcfba208a9 134 Pfam PF01475 Ferric uptake regulator family 11 125 2.1E-23 T 31-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 DFR85_01290 7d8181f05071bf7b328a46fcfba208a9 134 SUPERFAMILY SSF46785 5 129 6.43E-29 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_01290 7d8181f05071bf7b328a46fcfba208a9 134 Gene3D G3DSA:1.10.10.10 1 81 3.5E-23 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_15710 86f8f3ff9600a9e16aa543a6d52400e5 214 Hamap MF_00401 Peroxiredoxin. 1 205 45.665 T 31-10-2018 IPR022915 Peroxiredoxin, TDXH subfamily GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 DFR85_15710 86f8f3ff9600a9e16aa543a6d52400e5 214 Pfam PF00578 AhpC/TSA family 5 133 1.5E-31 T 31-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 DFR85_15710 86f8f3ff9600a9e16aa543a6d52400e5 214 Gene3D G3DSA:3.30.1020.20 143 212 5.7E-13 T 31-10-2018 DFR85_15710 86f8f3ff9600a9e16aa543a6d52400e5 214 Gene3D G3DSA:3.40.30.10 1 142 3.0E-43 T 31-10-2018 DFR85_15710 86f8f3ff9600a9e16aa543a6d52400e5 214 SUPERFAMILY SSF52833 2 205 6.81E-61 T 31-10-2018 IPR036249 Thioredoxin-like superfamily DFR85_15710 86f8f3ff9600a9e16aa543a6d52400e5 214 PIRSF PIRSF000239 1 208 1.2E-68 T 31-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 DFR85_15710 86f8f3ff9600a9e16aa543a6d52400e5 214 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 160 190 3.7E-7 T 31-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 DFR85_02785 016c49b46d30ee4841de319fcde4cb95 434 Gene3D G3DSA:3.20.20.140 50 406 3.9E-115 T 31-10-2018 DFR85_02785 016c49b46d30ee4841de319fcde4cb95 434 Pfam PF01979 Amidohydrolase family 46 418 2.1E-16 T 31-10-2018 IPR006680 Amidohydrolase-related GO:0016787 DFR85_02785 016c49b46d30ee4841de319fcde4cb95 434 SUPERFAMILY SSF51338 2 423 1.94E-19 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR85_02785 016c49b46d30ee4841de319fcde4cb95 434 Gene3D G3DSA:2.30.40.10 2 429 3.9E-115 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR85_02785 016c49b46d30ee4841de319fcde4cb95 434 SUPERFAMILY SSF51556 51 370 4.96E-68 T 31-10-2018 IPR032466 Metal-dependent hydrolase DFR85_01755 1c11bb03254a642257352bb1814762a0 535 Gene3D G3DSA:3.40.50.300 120 300 8.5E-17 T 31-10-2018 DFR85_01755 1c11bb03254a642257352bb1814762a0 535 Gene3D G3DSA:3.40.50.300 325 518 3.4E-32 T 31-10-2018 DFR85_01755 1c11bb03254a642257352bb1814762a0 535 SUPERFAMILY SSF52540 131 516 1.64E-32 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_01755 1c11bb03254a642257352bb1814762a0 535 Pfam PF01935 Domain of unknown function DUF87 132 381 8.5E-37 T 31-10-2018 IPR002789 Helicase HerA, central domain DFR85_09880 f31b38b23d366c270ba7fa028dd43304 110 Gene3D G3DSA:2.20.25.10 56 110 1.9E-23 T 31-10-2018 DFR85_09880 f31b38b23d366c270ba7fa028dd43304 110 Pfam PF02150 RNA polymerases M/15 Kd subunit 1 35 1.2E-10 T 31-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 DFR85_09880 f31b38b23d366c270ba7fa028dd43304 110 PIRSF PIRSF005586 1 110 5.9E-37 T 31-10-2018 IPR012164 DNA-directed RNA polymerase subunit/transcription factor S GO:0006351 DFR85_09880 f31b38b23d366c270ba7fa028dd43304 110 SMART SM00661 2 53 1.5E-17 T 31-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 DFR85_09880 f31b38b23d366c270ba7fa028dd43304 110 SMART SM00440 69 108 6.5E-25 T 31-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 DFR85_09880 f31b38b23d366c270ba7fa028dd43304 110 SUPERFAMILY SSF57783 46 110 2.66E-22 T 31-10-2018 DFR85_09880 f31b38b23d366c270ba7fa028dd43304 110 Pfam PF01096 Transcription factor S-II (TFIIS) 70 107 9.8E-22 T 31-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 DFR85_09880 f31b38b23d366c270ba7fa028dd43304 110 ProSitePatterns PS01030 RNA polymerases M / 15 Kd subunits signature. 3 27 - T 31-10-2018 IPR019761 DNA-directed RNA polymerase M, 15kDa subunit, conserved site DFR85_09880 f31b38b23d366c270ba7fa028dd43304 110 ProSitePatterns PS00466 Zinc finger TFIIS-type signature. 71 106 - T 31-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 DFR85_09880 f31b38b23d366c270ba7fa028dd43304 110 SUPERFAMILY SSF57783 1 40 1.7E-5 T 31-10-2018 DFR85_09880 f31b38b23d366c270ba7fa028dd43304 110 TIGRFAM TIGR01384 TFS_arch: transcription factor S 2 110 6.8E-37 T 31-10-2018 IPR006288 Transcription factor S GO:0006355 DFR85_06800 1c46c49d22fa8657ac3739ec642bca2f 287 SMART SM00090 67 287 8.6E-27 T 31-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 DFR85_06800 1c46c49d22fa8657ac3739ec642bca2f 287 SUPERFAMILY SSF46785 6 89 3.71E-9 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_06800 1c46c49d22fa8657ac3739ec642bca2f 287 Pfam PF01163 RIO1 family 110 280 5.6E-35 T 31-10-2018 DFR85_06800 1c46c49d22fa8657ac3739ec642bca2f 287 SUPERFAMILY SSF56112 98 269 1.48E-26 T 31-10-2018 IPR011009 Protein kinase-like domain superfamily DFR85_06800 1c46c49d22fa8657ac3739ec642bca2f 287 Gene3D G3DSA:3.30.200.20 95 191 2.0E-24 T 31-10-2018 DFR85_06800 1c46c49d22fa8657ac3739ec642bca2f 287 Gene3D G3DSA:1.10.510.10 193 286 1.6E-21 T 31-10-2018 DFR85_06800 1c46c49d22fa8657ac3739ec642bca2f 287 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 223 235 - T 31-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 DFR85_13300 ab2b01a14351e524f72981b30ccc3ed6 897 SMART SM00487 27 222 2.3E-21 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain DFR85_13300 ab2b01a14351e524f72981b30ccc3ed6 897 Pfam PF00271 Helicase conserved C-terminal domain 382 495 8.8E-17 T 31-10-2018 IPR001650 Helicase, C-terminal DFR85_13300 ab2b01a14351e524f72981b30ccc3ed6 897 Pfam PF00176 SNF2 family N-terminal domain 51 202 4.9E-15 T 31-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 DFR85_13300 ab2b01a14351e524f72981b30ccc3ed6 897 SUPERFAMILY SSF52540 47 506 5.08E-40 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_13300 ab2b01a14351e524f72981b30ccc3ed6 897 Gene3D G3DSA:3.40.50.10810 29 286 3.6E-42 T 31-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily DFR85_13300 ab2b01a14351e524f72981b30ccc3ed6 897 SMART SM00490 414 496 8.2E-14 T 31-10-2018 IPR001650 Helicase, C-terminal DFR85_13300 ab2b01a14351e524f72981b30ccc3ed6 897 Gene3D G3DSA:3.40.50.300 313 525 1.0E-35 T 31-10-2018 DFR85_15140 657c9eec2d2c7cb69ff5210dda06af6a 130 SMART SM00670 4 120 0.0019 T 31-10-2018 IPR002716 PIN domain DFR85_15140 657c9eec2d2c7cb69ff5210dda06af6a 130 Pfam PF01850 PIN domain 6 122 1.1E-8 T 31-10-2018 IPR002716 PIN domain DFR85_15140 657c9eec2d2c7cb69ff5210dda06af6a 130 SUPERFAMILY SSF88723 5 123 7.85E-13 T 31-10-2018 IPR029060 PIN-like domain superfamily DFR85_15140 657c9eec2d2c7cb69ff5210dda06af6a 130 Gene3D G3DSA:3.40.50.1010 3 129 8.5E-8 T 31-10-2018 DFR85_00905 fb1027b1cd8ac6ea42b153ce348e0075 427 Gene3D G3DSA:3.10.20.70 1 107 8.2E-10 T 31-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DFR85_00905 fb1027b1cd8ac6ea42b153ce348e0075 427 Pfam PF00120 Glutamine synthetase, catalytic domain 107 422 6.1E-75 T 31-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DFR85_00905 fb1027b1cd8ac6ea42b153ce348e0075 427 Gene3D G3DSA:3.30.590.10 110 425 1.1E-80 T 31-10-2018 DFR85_00905 fb1027b1cd8ac6ea42b153ce348e0075 427 SUPERFAMILY SSF54368 3 101 6.8E-14 T 31-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DFR85_00905 fb1027b1cd8ac6ea42b153ce348e0075 427 SUPERFAMILY SSF55931 107 423 2.26E-75 T 31-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 DFR85_00905 fb1027b1cd8ac6ea42b153ce348e0075 427 SMART SM01230 106 351 2.3E-65 T 31-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DFR85_01255 67c97efbeb03f1fefb7abe545f0fc8d6 865 Gene3D G3DSA:3.40.50.300 1 262 4.9E-35 T 31-10-2018 DFR85_01255 67c97efbeb03f1fefb7abe545f0fc8d6 865 Gene3D G3DSA:3.40.50.300 624 858 4.7E-38 T 31-10-2018 DFR85_01255 67c97efbeb03f1fefb7abe545f0fc8d6 865 SUPERFAMILY SSF75712 376 474 7.45E-16 T 31-10-2018 DFR85_01255 67c97efbeb03f1fefb7abe545f0fc8d6 865 Pfam PF04423 Rad50 zinc hook motif 405 454 8.4E-9 T 31-10-2018 IPR013134 RAD50, zinc hook Reactome: R-HSA-2559586|Reactome: R-HSA-5685938|Reactome: R-HSA-5685939|Reactome: R-HSA-5685942|Reactome: R-HSA-5693548|Reactome: R-HSA-5693554|Reactome: R-HSA-5693565|Reactome: R-HSA-5693568|Reactome: R-HSA-5693571|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 DFR85_01255 67c97efbeb03f1fefb7abe545f0fc8d6 865 Hamap MF_00449 DNA double-strand break repair Rad50 ATPase [rad50]. 1 859 12.161 T 31-10-2018 IPR022982 DNA double-strand break repair Rad50 ATPase, archaeal type DFR85_01255 67c97efbeb03f1fefb7abe545f0fc8d6 865 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 593 840 1.4E-7 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 DFR85_01255 67c97efbeb03f1fefb7abe545f0fc8d6 865 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 114 2.1E-10 T 31-10-2018 IPR003395 RecF/RecN/SMC, N-terminal DFR85_01255 67c97efbeb03f1fefb7abe545f0fc8d6 865 Gene3D G3DSA:1.10.287.510 374 483 1.7E-16 T 31-10-2018 DFR85_01255 67c97efbeb03f1fefb7abe545f0fc8d6 865 SUPERFAMILY SSF52540 1 850 8.67E-33 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_01255 67c97efbeb03f1fefb7abe545f0fc8d6 865 SUPERFAMILY SSF52540 1 282 5.1E-20 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_02480 2ee845d8b323796c99f4815d6e61abe9 322 Pfam PF02615 Malate/L-lactate dehydrogenase 4 310 6.4E-76 T 31-10-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0016491|GO:0055114 DFR85_02480 2ee845d8b323796c99f4815d6e61abe9 322 SUPERFAMILY SSF89733 1 317 5.89E-74 T 31-10-2018 IPR036111 Malate/L-sulfolactate/L-lactate dehydrogenase-like superfamily GO:0016491|GO:0055114 DFR85_02480 2ee845d8b323796c99f4815d6e61abe9 322 Gene3D G3DSA:3.30.60.50 169 216 1.5E-70 T 31-10-2018 DFR85_02480 2ee845d8b323796c99f4815d6e61abe9 322 Gene3D G3DSA:1.10.1530.10 10 308 1.5E-70 T 31-10-2018 DFR85_02480 2ee845d8b323796c99f4815d6e61abe9 322 Gene3D G3DSA:3.30.1370.60 59 284 1.5E-70 T 31-10-2018 DFR85_12735 88580defef83dbe6f4772a4043ffec2e 266 Gene3D G3DSA:1.10.3720.10 2 253 1.4E-42 T 31-10-2018 IPR035906 MetI-like superfamily DFR85_12735 88580defef83dbe6f4772a4043ffec2e 266 SUPERFAMILY SSF161098 3 265 4.58E-52 T 31-10-2018 IPR035906 MetI-like superfamily DFR85_12735 88580defef83dbe6f4772a4043ffec2e 266 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 78 255 7.1E-17 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 DFR85_10490 5bffa485698732e1b4309eb18e2bd0ee 660 Gene3D G3DSA:3.40.50.140 3 150 3.5E-23 T 31-10-2018 DFR85_10490 5bffa485698732e1b4309eb18e2bd0ee 660 SMART SM00436 127 221 4.5E-24 T 31-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 DFR85_10490 5bffa485698732e1b4309eb18e2bd0ee 660 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 302 316 - T 31-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 DFR85_10490 5bffa485698732e1b4309eb18e2bd0ee 660 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 101 114 8.5E-21 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 DFR85_10490 5bffa485698732e1b4309eb18e2bd0ee 660 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 483 497 8.5E-21 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 DFR85_10490 5bffa485698732e1b4309eb18e2bd0ee 660 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 191 209 8.5E-21 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 DFR85_10490 5bffa485698732e1b4309eb18e2bd0ee 660 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 384 400 8.5E-21 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 DFR85_10490 5bffa485698732e1b4309eb18e2bd0ee 660 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 307 316 8.5E-21 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 DFR85_10490 5bffa485698732e1b4309eb18e2bd0ee 660 Gene3D G3DSA:1.10.460.10 160 568 5.1E-89 T 31-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 DFR85_10490 5bffa485698732e1b4309eb18e2bd0ee 660 Gene3D G3DSA:2.70.20.10 215 467 5.1E-89 T 31-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 DFR85_10490 5bffa485698732e1b4309eb18e2bd0ee 660 Pfam PF01131 DNA topoisomerase 151 557 1.7E-105 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 DFR85_10490 5bffa485698732e1b4309eb18e2bd0ee 660 Pfam PF01751 Toprim domain 6 135 2.3E-14 T 31-10-2018 IPR006171 TOPRIM domain DFR85_10490 5bffa485698732e1b4309eb18e2bd0ee 660 SUPERFAMILY SSF56712 6 598 2.35E-134 T 31-10-2018 IPR023405 DNA topoisomerase, type IA, core domain DFR85_10490 5bffa485698732e1b4309eb18e2bd0ee 660 TIGRFAM TIGR01057 topA_arch: DNA topoisomerase I 9 597 9.2E-175 T 31-10-2018 IPR005739 DNA topoisomerase I, archeal-type GO:0003677|GO:0003916|GO:0006265 DFR85_10490 5bffa485698732e1b4309eb18e2bd0ee 660 SMART SM00437 265 520 8.9E-56 T 31-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 DFR85_10490 5bffa485698732e1b4309eb18e2bd0ee 660 SMART SM00493 5 127 3.5E-12 T 31-10-2018 IPR006171 TOPRIM domain DFR85_10490 5bffa485698732e1b4309eb18e2bd0ee 660 Gene3D G3DSA:1.10.290.10 273 398 5.1E-89 T 31-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 DFR85_15425 dbd3bb7cd2fbcbfcaf291d606952a5b6 489 SUPERFAMILY SSF47203 262 481 1.78E-39 T 31-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 DFR85_15425 dbd3bb7cd2fbcbfcaf291d606952a5b6 489 PIRSF PIRSF000331 1 489 3.2E-152 T 31-10-2018 IPR004925 HpaB/PvcC/4-BUDH DFR85_15425 dbd3bb7cd2fbcbfcaf291d606952a5b6 489 Gene3D G3DSA:2.40.110.10 145 272 8.0E-38 T 31-10-2018 DFR85_15425 dbd3bb7cd2fbcbfcaf291d606952a5b6 489 Gene3D G3DSA:1.10.3140.10 1 143 1.4E-31 T 31-10-2018 DFR85_15425 dbd3bb7cd2fbcbfcaf291d606952a5b6 489 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 282 475 5.0E-50 T 31-10-2018 IPR024719 HpaB/PvcC/4-BUDH C-terminal DFR85_15425 dbd3bb7cd2fbcbfcaf291d606952a5b6 489 SUPERFAMILY SSF56645 1 272 2.99E-72 T 31-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 DFR85_15425 dbd3bb7cd2fbcbfcaf291d606952a5b6 489 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 5 270 2.1E-85 T 31-10-2018 IPR024674 HpaB/PvcC/4-BUDH N-terminal DFR85_15425 dbd3bb7cd2fbcbfcaf291d606952a5b6 489 Gene3D G3DSA:1.20.140.10 277 485 1.4E-50 T 31-10-2018 DFR85_07670 fc84e5ebd10a945cc4bae7ea827da7bc 312 Gene3D G3DSA:3.90.650.10 139 308 1.8E-20 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily DFR85_07670 fc84e5ebd10a945cc4bae7ea827da7bc 312 SUPERFAMILY SSF55326 2 130 4.88E-19 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily DFR85_07670 fc84e5ebd10a945cc4bae7ea827da7bc 312 Pfam PF00586 AIR synthase related protein, N-terminal domain 49 130 1.6E-9 T 31-10-2018 IPR016188 PurM-like, N-terminal domain DFR85_07670 fc84e5ebd10a945cc4bae7ea827da7bc 312 Gene3D G3DSA:3.30.1330.10 1 131 1.2E-19 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily DFR85_07670 fc84e5ebd10a945cc4bae7ea827da7bc 312 SUPERFAMILY SSF56042 140 296 1.02E-19 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily DFR85_04285 44818a4cfd55f0e1f2dd5aebc098abfb 404 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2 169 7.3E-49 T 31-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 DFR85_04285 44818a4cfd55f0e1f2dd5aebc098abfb 404 PIRSF PIRSF500134 1 404 2.0E-128 T 31-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 DFR85_04285 44818a4cfd55f0e1f2dd5aebc098abfb 404 PIRSF PIRSF000124 1 404 3.6E-121 T 31-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 DFR85_04285 44818a4cfd55f0e1f2dd5aebc098abfb 404 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 301 389 9.4E-25 T 31-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 DFR85_04285 44818a4cfd55f0e1f2dd5aebc098abfb 404 SUPERFAMILY SSF48179 185 283 1.63E-32 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 DFR85_04285 44818a4cfd55f0e1f2dd5aebc098abfb 404 Gene3D G3DSA:3.40.50.720 216 404 1.5E-61 T 31-10-2018 DFR85_04285 44818a4cfd55f0e1f2dd5aebc098abfb 404 Gene3D G3DSA:1.20.5.100 188 215 5.7E-18 T 31-10-2018 DFR85_04285 44818a4cfd55f0e1f2dd5aebc098abfb 404 SUPERFAMILY SSF51735 2 174 1.64E-42 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_04285 44818a4cfd55f0e1f2dd5aebc098abfb 404 SMART SM00984 300 389 1.8E-32 T 31-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 DFR85_04285 44818a4cfd55f0e1f2dd5aebc098abfb 404 Gene3D G3DSA:3.40.50.720 1 187 5.3E-60 T 31-10-2018 DFR85_04285 44818a4cfd55f0e1f2dd5aebc098abfb 404 SUPERFAMILY SSF52413 287 396 6.28E-28 T 31-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 DFR85_04285 44818a4cfd55f0e1f2dd5aebc098abfb 404 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 185 277 4.1E-38 T 31-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 DFR85_04285 44818a4cfd55f0e1f2dd5aebc098abfb 404 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 2 385 4.5E-127 T 31-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 DFR85_05795 1b95836e9565ccd0aa2c0b6e9789aadc 414 Hamap MF_01027 3-isopropylmalate dehydratase large subunit [leuC]. 2 413 46.799 T 31-10-2018 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 DFR85_05795 1b95836e9565ccd0aa2c0b6e9789aadc 414 TIGRFAM TIGR01343 hacA_fam: homoaconitate hydratase family protein 3 411 4.2E-149 T 31-10-2018 IPR006251 Homoaconitase/3-isopropylmalate dehydratase, large subunit GO:0008652|GO:0016836|GO:0051539 KEGG: 00290+4.2.1.33 DFR85_05795 1b95836e9565ccd0aa2c0b6e9789aadc 414 Gene3D G3DSA:3.30.499.20 3 266 1.5E-82 T 31-10-2018 DFR85_05795 1b95836e9565ccd0aa2c0b6e9789aadc 414 ProSitePatterns PS01244 Aconitase family signature 2. 346 359 - T 31-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 DFR85_05795 1b95836e9565ccd0aa2c0b6e9789aadc 414 TIGRFAM TIGR02086 IPMI_arch: 3-isopropylmalate dehydratase, large subunit 2 412 3.3E-177 T 31-10-2018 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 DFR85_05795 1b95836e9565ccd0aa2c0b6e9789aadc 414 SUPERFAMILY SSF53732 2 413 5.36E-123 T 31-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 DFR85_05795 1b95836e9565ccd0aa2c0b6e9789aadc 414 Gene3D G3DSA:3.30.499.10 269 413 5.2E-50 T 31-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 DFR85_05795 1b95836e9565ccd0aa2c0b6e9789aadc 414 Pfam PF00330 Aconitase family (aconitate hydratase) 281 405 1.4E-27 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 DFR85_05795 1b95836e9565ccd0aa2c0b6e9789aadc 414 Pfam PF00330 Aconitase family (aconitate hydratase) 25 278 5.6E-47 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 DFR85_05795 1b95836e9565ccd0aa2c0b6e9789aadc 414 PRINTS PR00415 Aconitase family signature 292 303 5.3E-12 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 DFR85_05795 1b95836e9565ccd0aa2c0b6e9789aadc 414 PRINTS PR00415 Aconitase family signature 110 123 5.3E-12 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 DFR85_05795 1b95836e9565ccd0aa2c0b6e9789aadc 414 PRINTS PR00415 Aconitase family signature 124 139 5.3E-12 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 DFR85_05795 1b95836e9565ccd0aa2c0b6e9789aadc 414 PRINTS PR00415 Aconitase family signature 346 359 5.3E-12 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 DFR85_06505 99fdcabbc2ca26be23aa59a4baf64f83 379 Pfam PF00005 ABC transporter 224 256 5.7E-7 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR85_06505 99fdcabbc2ca26be23aa59a4baf64f83 379 ProSitePatterns PS00211 ABC transporters family signature. 299 313 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DFR85_06505 99fdcabbc2ca26be23aa59a4baf64f83 379 SUPERFAMILY SSF52540 14 186 5.82E-26 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_06505 99fdcabbc2ca26be23aa59a4baf64f83 379 Gene3D G3DSA:3.40.50.300 260 377 1.9E-21 T 31-10-2018 DFR85_06505 99fdcabbc2ca26be23aa59a4baf64f83 379 Pfam PF00005 ABC transporter 13 139 4.4E-15 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR85_06505 99fdcabbc2ca26be23aa59a4baf64f83 379 SUPERFAMILY SSF52540 221 372 2.81E-34 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_06505 99fdcabbc2ca26be23aa59a4baf64f83 379 SMART SM00382 17 201 0.0044 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_06505 99fdcabbc2ca26be23aa59a4baf64f83 379 SMART SM00382 232 374 3.0E-10 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_06505 99fdcabbc2ca26be23aa59a4baf64f83 379 Pfam PF00005 ABC transporter 260 327 1.3E-7 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR85_06505 99fdcabbc2ca26be23aa59a4baf64f83 379 Gene3D G3DSA:3.40.50.300 217 259 1.5E-7 T 31-10-2018 DFR85_06505 99fdcabbc2ca26be23aa59a4baf64f83 379 Gene3D G3DSA:3.40.50.300 9 216 3.8E-26 T 31-10-2018 DFR85_07745 cf866c375df7bb66bd15720d3457b6f4 880 Gene3D G3DSA:2.20.25.410 828 880 5.1E-25 T 31-10-2018 DFR85_07745 cf866c375df7bb66bd15720d3457b6f4 880 SUPERFAMILY SSF64484 4 864 0.0 T 31-10-2018 DFR85_07745 cf866c375df7bb66bd15720d3457b6f4 880 Gene3D G3DSA:1.10.132.30 648 791 5.5E-46 T 31-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR85_07745 cf866c375df7bb66bd15720d3457b6f4 880 Gene3D G3DSA:3.30.1490.180 348 413 8.3E-83 T 31-10-2018 DFR85_07745 cf866c375df7bb66bd15720d3457b6f4 880 Pfam PF00623 RNA polymerase Rpb1, domain 2 315 482 2.9E-75 T 31-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR85_07745 cf866c375df7bb66bd15720d3457b6f4 880 Gene3D G3DSA:2.60.40.2940 555 601 3.8E-26 T 31-10-2018 DFR85_07745 cf866c375df7bb66bd15720d3457b6f4 880 TIGRFAM TIGR02390 RNA_pol_rpoA1: DNA-directed RNA polymerase subunit A' 4 872 0.0 T 31-10-2018 IPR012758 DNA-directed RNA polymerase subunit A' (Rpo1N) GO:0003677|GO:0003899|GO:0006351|GO:0008270 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR85_07745 cf866c375df7bb66bd15720d3457b6f4 880 Gene3D G3DSA:1.20.120.1280 229 278 2.4E-11 T 31-10-2018 DFR85_07745 cf866c375df7bb66bd15720d3457b6f4 880 Gene3D G3DSA:1.20.120.1280 1 118 7.0E-30 T 31-10-2018 DFR85_07745 cf866c375df7bb66bd15720d3457b6f4 880 Gene3D G3DSA:1.10.10.1950 483 536 1.2E-12 T 31-10-2018 DFR85_07745 cf866c375df7bb66bd15720d3457b6f4 880 Gene3D G3DSA:1.10.10.1950 602 647 4.9E-13 T 31-10-2018 DFR85_07745 cf866c375df7bb66bd15720d3457b6f4 880 Pfam PF04983 RNA polymerase Rpb1, domain 3 485 651 1.1E-35 T 31-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR85_07745 cf866c375df7bb66bd15720d3457b6f4 880 Pfam PF04998 RNA polymerase Rpb1, domain 5 789 854 1.8E-23 T 31-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR85_07745 cf866c375df7bb66bd15720d3457b6f4 880 Pfam PF05000 RNA polymerase Rpb1, domain 4 676 782 2.2E-32 T 31-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR85_07745 cf866c375df7bb66bd15720d3457b6f4 880 Gene3D G3DSA:2.40.40.20 305 477 8.3E-83 T 31-10-2018 DFR85_07745 cf866c375df7bb66bd15720d3457b6f4 880 Pfam PF04997 RNA polymerase Rpb1, domain 1 4 313 5.7E-98 T 31-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR85_07745 cf866c375df7bb66bd15720d3457b6f4 880 SMART SM00663 205 510 1.5E-206 T 31-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR85_01280 7931b1fb80544ae8a58be6a1355f3133 268 SUPERFAMILY SSF54631 4 121 1.12E-18 T 31-10-2018 DFR85_01280 7931b1fb80544ae8a58be6a1355f3133 268 Gene3D G3DSA:3.10.580.10 3 126 1.7E-18 T 31-10-2018 DFR85_01280 7931b1fb80544ae8a58be6a1355f3133 268 SMART SM00116 6 54 2.2 T 31-10-2018 IPR000644 CBS domain DFR85_01280 7931b1fb80544ae8a58be6a1355f3133 268 SMART SM00116 202 250 3.9E-8 T 31-10-2018 IPR000644 CBS domain DFR85_01280 7931b1fb80544ae8a58be6a1355f3133 268 SMART SM00116 138 184 9.3E-4 T 31-10-2018 IPR000644 CBS domain DFR85_01280 7931b1fb80544ae8a58be6a1355f3133 268 SMART SM00116 74 122 17.0 T 31-10-2018 IPR000644 CBS domain DFR85_01280 7931b1fb80544ae8a58be6a1355f3133 268 Gene3D G3DSA:3.10.580.10 127 266 1.4E-29 T 31-10-2018 DFR85_01280 7931b1fb80544ae8a58be6a1355f3133 268 SUPERFAMILY SSF54631 130 251 2.62E-29 T 31-10-2018 DFR85_01280 7931b1fb80544ae8a58be6a1355f3133 268 Pfam PF00571 CBS domain 68 117 2.6E-4 T 31-10-2018 IPR000644 CBS domain DFR85_01280 7931b1fb80544ae8a58be6a1355f3133 268 Pfam PF00571 CBS domain 195 250 6.7E-13 T 31-10-2018 IPR000644 CBS domain DFR85_01280 7931b1fb80544ae8a58be6a1355f3133 268 Pfam PF00571 CBS domain 131 180 1.2E-8 T 31-10-2018 IPR000644 CBS domain DFR85_01280 7931b1fb80544ae8a58be6a1355f3133 268 Pfam PF00571 CBS domain 6 54 0.0011 T 31-10-2018 IPR000644 CBS domain DFR85_08345 f9ea365de5410129c260e1a489d30b28 147 Pfam PF01967 MoaC family 5 143 1.1E-45 T 31-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 DFR85_08345 f9ea365de5410129c260e1a489d30b28 147 SUPERFAMILY SSF55040 3 144 3.27E-46 T 31-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 DFR85_08345 f9ea365de5410129c260e1a489d30b28 147 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 3 126 4.3E-49 T 31-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 DFR85_08345 f9ea365de5410129c260e1a489d30b28 147 Hamap MF_01224_A Cyclic pyranopterin monophosphate synthase [moaC]. 1 145 33.978 T 31-10-2018 IPR023047 Probable cyclic pyranopterin monophosphate synthase accessory protein, archaea KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823 DFR85_08345 f9ea365de5410129c260e1a489d30b28 147 Gene3D G3DSA:3.30.70.640 1 147 3.3E-58 T 31-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 DFR85_07410 53883547f10cbde0f602921d50efffca 422 Gene3D G3DSA:3.40.50.800 329 421 7.5E-17 T 31-10-2018 IPR036621 Anticodon-binding domain superfamily DFR85_07410 53883547f10cbde0f602921d50efffca 422 Gene3D G3DSA:3.30.930.10 2 328 2.8E-88 T 31-10-2018 DFR85_07410 53883547f10cbde0f602921d50efffca 422 SUPERFAMILY SSF52954 329 422 2.11E-18 T 31-10-2018 DFR85_07410 53883547f10cbde0f602921d50efffca 422 Pfam PF03129 Anticodon binding domain 331 419 7.2E-12 T 31-10-2018 IPR004154 Anticodon-binding DFR85_07410 53883547f10cbde0f602921d50efffca 422 PIRSF PIRSF001549 1 422 3.0E-110 T 31-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 DFR85_07410 53883547f10cbde0f602921d50efffca 422 Pfam PF13393 Histidyl-tRNA synthetase 9 317 2.3E-62 T 31-10-2018 DFR85_07410 53883547f10cbde0f602921d50efffca 422 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 2 420 27.235 T 31-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 DFR85_07410 53883547f10cbde0f602921d50efffca 422 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 6 409 4.9E-109 T 31-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 DFR85_07410 53883547f10cbde0f602921d50efffca 422 SUPERFAMILY SSF55681 5 321 5.57E-82 T 31-10-2018 DFR85_11605 e0e2a172add8396ce774e5102c99943e 760 TIGRFAM TIGR02401 trehalose_TreY: malto-oligosyltrehalose synthase 4 758 2.5E-240 T 31-10-2018 IPR012767 Maltooligosyl trehalose synthase KEGG: 00500+5.4.99.15|MetaCyc: PWY-2661 DFR85_11605 e0e2a172add8396ce774e5102c99943e 760 SMART SM00642 3 404 3.7E-8 T 31-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 DFR85_11605 e0e2a172add8396ce774e5102c99943e 760 Gene3D G3DSA:1.10.10.470 493 592 3.4E-176 T 31-10-2018 DFR85_11605 e0e2a172add8396ce774e5102c99943e 760 SUPERFAMILY SSF51445 6 675 5.29E-125 T 31-10-2018 IPR017853 Glycoside hydrolase superfamily DFR85_11605 e0e2a172add8396ce774e5102c99943e 760 Gene3D G3DSA:1.10.150.200 324 449 3.4E-176 T 31-10-2018 DFR85_11605 e0e2a172add8396ce774e5102c99943e 760 Pfam PF00128 Alpha amylase, catalytic domain 17 253 3.7E-27 T 31-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 DFR85_11605 e0e2a172add8396ce774e5102c99943e 760 Gene3D G3DSA:3.20.20.80 5 676 3.4E-176 T 31-10-2018 DFR85_11605 e0e2a172add8396ce774e5102c99943e 760 Gene3D G3DSA:3.30.1590.10 88 221 3.4E-176 T 31-10-2018 DFR85_11405 5e2773cd64ba9544946df5fc6368d60f 443 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 324 421 4.3E-14 T 31-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 DFR85_11405 5e2773cd64ba9544946df5fc6368d60f 443 PIRSF PIRSF000350 1 437 2.2E-62 T 31-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 DFR85_11405 5e2773cd64ba9544946df5fc6368d60f 443 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 36 51 2.3E-47 T 31-10-2018 DFR85_11405 5e2773cd64ba9544946df5fc6368d60f 443 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 320 341 2.3E-47 T 31-10-2018 DFR85_11405 5e2773cd64ba9544946df5fc6368d60f 443 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 2.3E-47 T 31-10-2018 DFR85_11405 5e2773cd64ba9544946df5fc6368d60f 443 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 243 257 2.3E-47 T 31-10-2018 DFR85_11405 5e2773cd64ba9544946df5fc6368d60f 443 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 130 139 2.3E-47 T 31-10-2018 DFR85_11405 5e2773cd64ba9544946df5fc6368d60f 443 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 164 189 2.3E-47 T 31-10-2018 DFR85_11405 5e2773cd64ba9544946df5fc6368d60f 443 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 399 419 2.3E-47 T 31-10-2018 DFR85_11405 5e2773cd64ba9544946df5fc6368d60f 443 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 284 291 2.3E-47 T 31-10-2018 DFR85_11405 5e2773cd64ba9544946df5fc6368d60f 443 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 37 47 - T 31-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 DFR85_11405 5e2773cd64ba9544946df5fc6368d60f 443 Gene3D G3DSA:3.50.50.60 139 249 1.7E-78 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_11405 5e2773cd64ba9544946df5fc6368d60f 443 SUPERFAMILY SSF55424 320 431 2.92E-20 T 31-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 DFR85_11405 5e2773cd64ba9544946df5fc6368d60f 443 SUPERFAMILY SSF51905 1 314 4.1E-48 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_11405 5e2773cd64ba9544946df5fc6368d60f 443 Gene3D G3DSA:3.50.50.60 6 309 1.7E-78 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_11405 5e2773cd64ba9544946df5fc6368d60f 443 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 305 2.8E-49 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR85_11405 5e2773cd64ba9544946df5fc6368d60f 443 Gene3D G3DSA:3.30.390.30 317 429 9.8E-21 T 31-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 DFR85_11405 5e2773cd64ba9544946df5fc6368d60f 443 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 242 258 5.4E-24 T 31-10-2018 DFR85_11405 5e2773cd64ba9544946df5fc6368d60f 443 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 269 291 5.4E-24 T 31-10-2018 DFR85_11405 5e2773cd64ba9544946df5fc6368d60f 443 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 164 182 5.4E-24 T 31-10-2018 DFR85_11405 5e2773cd64ba9544946df5fc6368d60f 443 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 127 145 5.4E-24 T 31-10-2018 DFR85_11405 5e2773cd64ba9544946df5fc6368d60f 443 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 5.4E-24 T 31-10-2018 DFR85_09860 2bd11c6c107ee8fd72f860e2a125c5c5 332 Gene3D G3DSA:3.40.50.11840 16 98 8.7E-86 T 31-10-2018 DFR85_09860 2bd11c6c107ee8fd72f860e2a125c5c5 332 TIGRFAM TIGR03682 arCOG04112: diphthamide biosynthesis enzyme Dph2 19 329 1.2E-97 T 31-10-2018 IPR022428 Diphthamide synthesis Dph2, archaea GO:0017183 MetaCyc: PWY-6482|MetaCyc: PWY-7546 DFR85_09860 2bd11c6c107ee8fd72f860e2a125c5c5 332 Gene3D G3DSA:3.40.50.11860 217 318 8.7E-86 T 31-10-2018 DFR85_09860 2bd11c6c107ee8fd72f860e2a125c5c5 332 PIRSF PIRSF004967 1 332 3.1E-90 T 31-10-2018 IPR035435 Diphthamide synthesis DHP1/DPH2, eukaryotes and archaea GO:0017183 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 DFR85_09860 2bd11c6c107ee8fd72f860e2a125c5c5 332 Pfam PF01866 Putative diphthamide synthesis protein 26 321 1.7E-78 T 31-10-2018 IPR016435 Diphthamide synthesis DPH1/DPH2 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 DFR85_09860 2bd11c6c107ee8fd72f860e2a125c5c5 332 TIGRFAM TIGR00322 diphth2_R: diphthamide biosynthesis enzyme Dph1/Dph2 domain 3 320 5.1E-96 T 31-10-2018 IPR016435 Diphthamide synthesis DPH1/DPH2 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 DFR85_09860 2bd11c6c107ee8fd72f860e2a125c5c5 332 Gene3D G3DSA:3.40.50.11850 101 216 8.7E-86 T 31-10-2018 DFR85_10575 78bd5580e4ea25ffba2fa405fde8a438 348 Pfam PF02885 Glycosyl transferase family, helical bundle domain 4 66 1.9E-14 T 31-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 DFR85_10575 78bd5580e4ea25ffba2fa405fde8a438 348 Gene3D G3DSA:3.40.1030.10 72 314 1.4E-112 T 31-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 DFR85_10575 78bd5580e4ea25ffba2fa405fde8a438 348 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 7 314 2.7E-99 T 31-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 DFR85_10575 78bd5580e4ea25ffba2fa405fde8a438 348 Pfam PF00591 Glycosyl transferase family, a/b domain 73 311 1.1E-68 T 31-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 DFR85_10575 78bd5580e4ea25ffba2fa405fde8a438 348 SUPERFAMILY SSF52418 72 331 5.89E-74 T 31-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 DFR85_10575 78bd5580e4ea25ffba2fa405fde8a438 348 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 5 342 32.494 T 31-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 DFR85_10575 78bd5580e4ea25ffba2fa405fde8a438 348 Gene3D G3DSA:1.20.970.10 7 181 1.4E-112 T 31-10-2018 DFR85_10575 78bd5580e4ea25ffba2fa405fde8a438 348 SUPERFAMILY SSF47648 1 68 5.36E-16 T 31-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 DFR85_00800 0b43227750de57f9eed9f8add0396f35 517 Gene3D G3DSA:3.50.50.60 1 114 8.6E-15 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_00800 0b43227750de57f9eed9f8add0396f35 517 Gene3D G3DSA:3.50.50.60 168 332 6.3E-20 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_00800 0b43227750de57f9eed9f8add0396f35 517 Pfam PF13450 NAD(P)-binding Rossmann-like domain 6 60 6.6E-12 T 31-10-2018 DFR85_00800 0b43227750de57f9eed9f8add0396f35 517 PRINTS PR00419 Adrenodoxin reductase family signature 26 39 4.5E-6 T 31-10-2018 DFR85_00800 0b43227750de57f9eed9f8add0396f35 517 PRINTS PR00419 Adrenodoxin reductase family signature 3 25 4.5E-6 T 31-10-2018 DFR85_00800 0b43227750de57f9eed9f8add0396f35 517 SUPERFAMILY SSF51905 1 300 4.81E-48 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_09325 1b2a0fa627070f236927f974e7dc6a72 101 Gene3D G3DSA:1.10.10.10 1 101 2.1E-14 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_09325 1b2a0fa627070f236927f974e7dc6a72 101 Pfam PF01022 Bacterial regulatory protein, arsR family 24 67 4.3E-10 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DFR85_09325 1b2a0fa627070f236927f974e7dc6a72 101 SUPERFAMILY SSF46785 19 87 1.28E-14 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_04610 f1a3a02d9a953e94bc5f212cdceb2ee1 241 Hamap MF_00722 Endonuclease NucS [nucS]. 27 237 33.115 T 31-10-2018 IPR002793 Endonuclease NucS GO:0004519 DFR85_04610 f1a3a02d9a953e94bc5f212cdceb2ee1 241 Gene3D G3DSA:2.70.180.20 4 121 3.2E-31 T 31-10-2018 DFR85_04610 f1a3a02d9a953e94bc5f212cdceb2ee1 241 Gene3D G3DSA:3.40.1350.10 122 230 6.2E-30 T 31-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 DFR85_04610 f1a3a02d9a953e94bc5f212cdceb2ee1 241 Pfam PF01939 Endonuclease NucS 26 227 2.3E-55 T 31-10-2018 IPR002793 Endonuclease NucS GO:0004519 DFR85_10840 b24b3553162d924666aa1a4675931939 94 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 92 1.9E-27 T 31-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 DFR85_10840 b24b3553162d924666aa1a4675931939 94 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 1 93 19.869 T 31-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 DFR85_10840 b24b3553162d924666aa1a4675931939 94 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 18 87 8.9E-18 T 31-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 DFR85_10840 b24b3553162d924666aa1a4675931939 94 Gene3D G3DSA:1.10.20.60 2 90 3.7E-22 T 31-10-2018 DFR85_10840 b24b3553162d924666aa1a4675931939 94 SUPERFAMILY SSF141000 4 89 8.63E-20 T 31-10-2018 IPR036113 Glu-tRNAGln amidotransferase superfamily, subunit C GO:0006450 DFR85_11515 834c95674a265ba7514ebfd9402cf251 208 Gene3D G3DSA:3.40.50.300 1 208 8.7E-46 T 31-10-2018 DFR85_11515 834c95674a265ba7514ebfd9402cf251 208 SMART SM00382 25 203 2.2E-7 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_11515 834c95674a265ba7514ebfd9402cf251 208 Pfam PF00005 ABC transporter 17 152 3.7E-20 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR85_11515 834c95674a265ba7514ebfd9402cf251 208 SUPERFAMILY SSF52540 1 204 2.11E-35 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_07760 25014084fe537bccf35482057547fbb5 143 SUPERFAMILY SSF54814 15 75 3.07E-11 T 31-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 DFR85_07760 25014084fe537bccf35482057547fbb5 143 Gene3D G3DSA:3.30.300.20 75 142 4.4E-26 T 31-10-2018 IPR015946 K homology domain-like, alpha/beta DFR85_07760 25014084fe537bccf35482057547fbb5 143 Pfam PF07650 KH domain 14 75 3.9E-12 T 31-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07760 25014084fe537bccf35482057547fbb5 143 Hamap MF_00945_A Transcription termination/antitermination protein NusA [nusA]. 2 143 31.644 T 31-10-2018 IPR010212 Probable transcription termination protein NusA, archaeal DFR85_07760 25014084fe537bccf35482057547fbb5 143 TIGRFAM TIGR01952 nusA_arch: NusA family KH domain protein, archaeal 3 143 6.8E-53 T 31-10-2018 IPR010212 Probable transcription termination protein NusA, archaeal DFR85_07760 25014084fe537bccf35482057547fbb5 143 SUPERFAMILY SSF54814 76 139 3.14E-11 T 31-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 DFR85_07760 25014084fe537bccf35482057547fbb5 143 Gene3D G3DSA:3.30.300.20 2 74 4.7E-29 T 31-10-2018 IPR015946 K homology domain-like, alpha/beta DFR85_06640 bf61ea2d6aebd7a85e3eec643e8d6114 540 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 15 181 7.2E-17 T 31-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 DFR85_06640 bf61ea2d6aebd7a85e3eec643e8d6114 540 SUPERFAMILY SSF52467 197 385 1.96E-40 T 31-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily DFR85_06640 bf61ea2d6aebd7a85e3eec643e8d6114 540 SUPERFAMILY SSF52518 8 194 6.96E-17 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR85_06640 bf61ea2d6aebd7a85e3eec643e8d6114 540 Gene3D G3DSA:3.40.50.1220 200 362 6.3E-41 T 31-10-2018 DFR85_06640 bf61ea2d6aebd7a85e3eec643e8d6114 540 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 203 338 5.4E-32 T 31-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 DFR85_06640 bf61ea2d6aebd7a85e3eec643e8d6114 540 Gene3D G3DSA:3.40.50.970 5 199 2.9E-16 T 31-10-2018 DFR85_05415 c4ad4eb41ba1af805e48104d5bc7c496 1021 SMART SM00245 804 994 1.5E-25 T 31-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 DFR85_05415 c4ad4eb41ba1af805e48104d5bc7c496 1021 Pfam PF03572 Peptidase family S41 838 993 1.9E-23 T 31-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 DFR85_05415 c4ad4eb41ba1af805e48104d5bc7c496 1021 PIRSF PIRSF036421 1 1021 0.0 T 31-10-2018 IPR012393 Tricorn protease GO:0008236 DFR85_05415 c4ad4eb41ba1af805e48104d5bc7c496 1021 Gene3D G3DSA:3.90.226.10 816 1021 1.3E-67 T 31-10-2018 DFR85_05415 c4ad4eb41ba1af805e48104d5bc7c496 1021 Gene3D G3DSA:3.30.750.44 642 711 1.4E-33 T 31-10-2018 DFR85_05415 c4ad4eb41ba1af805e48104d5bc7c496 1021 SUPERFAMILY SSF50156 722 803 8.63E-18 T 31-10-2018 IPR036034 PDZ superfamily GO:0005515 DFR85_05415 c4ad4eb41ba1af805e48104d5bc7c496 1021 Pfam PF14685 Tricorn protease PDZ domain 722 804 1.4E-26 T 31-10-2018 IPR029414 Tricorn protease, PDZ domain DFR85_05415 c4ad4eb41ba1af805e48104d5bc7c496 1021 Gene3D G3DSA:2.30.42.10 720 815 7.1E-14 T 31-10-2018 DFR85_05415 c4ad4eb41ba1af805e48104d5bc7c496 1021 Pfam PF14684 Tricorn protease C1 domain 643 710 1.4E-29 T 31-10-2018 IPR028204 Tricorn protease C1 domain DFR85_05415 c4ad4eb41ba1af805e48104d5bc7c496 1021 Pfam PF07676 WD40-like Beta Propeller Repeat 37 66 8.0E-5 T 31-10-2018 IPR011659 WD40-like Beta Propeller DFR85_05415 c4ad4eb41ba1af805e48104d5bc7c496 1021 Pfam PF07676 WD40-like Beta Propeller Repeat 446 481 8.9E-4 T 31-10-2018 IPR011659 WD40-like Beta Propeller DFR85_05415 c4ad4eb41ba1af805e48104d5bc7c496 1021 Gene3D G3DSA:2.120.10.60 1 267 2.5E-89 T 31-10-2018 DFR85_05415 c4ad4eb41ba1af805e48104d5bc7c496 1021 SUPERFAMILY SSF52096 640 1018 2.61E-71 T 31-10-2018 IPR029045 ClpP/crotonase-like domain superfamily DFR85_05415 c4ad4eb41ba1af805e48104d5bc7c496 1021 SUPERFAMILY SSF69304 10 264 5.62E-33 T 31-10-2018 DFR85_05415 c4ad4eb41ba1af805e48104d5bc7c496 1021 SUPERFAMILY SSF82171 173 473 5.1E-21 T 31-10-2018 DFR85_05415 c4ad4eb41ba1af805e48104d5bc7c496 1021 Gene3D G3DSA:2.130.10.10 285 622 3.1E-81 T 31-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 DFR85_03760 344bb226cececb232c9d3e4da3fe41d3 293 PIRSF PIRSF005355 1 293 1.1E-50 T 31-10-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 DFR85_03760 344bb226cececb232c9d3e4da3fe41d3 293 Pfam PF01040 UbiA prenyltransferase family 31 254 2.1E-32 T 31-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 DFR85_07380 1bb87eda7142e3630cc1726d7729cc70 177 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 97 168 3.8E-8 T 31-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 DFR85_07380 1bb87eda7142e3630cc1726d7729cc70 177 Pfam PF14810 Patch-forming domain C2 of tRNA-guanine transglycosylase 24 96 1.5E-16 T 31-10-2018 IPR029402 tRNA-guanine transglycosylase, patch-forming domain C2 MetaCyc: PWY-6711|MetaCyc: PWY-7923 DFR85_07380 1bb87eda7142e3630cc1726d7729cc70 177 SUPERFAMILY SSF88697 98 169 1.88E-17 T 31-10-2018 IPR015947 PUA-like superfamily DFR85_07380 1bb87eda7142e3630cc1726d7729cc70 177 Gene3D G3DSA:2.30.130.10 95 171 2.1E-26 T 31-10-2018 IPR036974 PUA domain superfamily GO:0003723 DFR85_07380 1bb87eda7142e3630cc1726d7729cc70 177 SUPERFAMILY SSF88802 16 93 6.15E-11 T 31-10-2018 DFR85_07380 1bb87eda7142e3630cc1726d7729cc70 177 SMART SM00359 98 172 4.5E-9 T 31-10-2018 IPR002478 PUA domain GO:0003723 DFR85_07380 1bb87eda7142e3630cc1726d7729cc70 177 Pfam PF01472 PUA domain 99 168 8.5E-12 T 31-10-2018 IPR002478 PUA domain GO:0003723 DFR85_07380 1bb87eda7142e3630cc1726d7729cc70 177 Gene3D G3DSA:3.10.450.90 17 93 1.1E-8 T 31-10-2018 IPR038250 TGT, patch-forming C2 domain superfamily MetaCyc: PWY-6711|MetaCyc: PWY-7923 DFR85_12665 5c6c998d545d406771539b0be51a76e2 478 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 277 288 - T 31-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 DFR85_12665 5c6c998d545d406771539b0be51a76e2 478 SUPERFAMILY SSF53720 4 476 1.14E-136 T 31-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 DFR85_12665 5c6c998d545d406771539b0be51a76e2 478 Pfam PF00171 Aldehyde dehydrogenase family 12 472 3.0E-146 T 31-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 DFR85_12665 5c6c998d545d406771539b0be51a76e2 478 Gene3D G3DSA:3.40.605.10 13 472 4.2E-147 T 31-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 DFR85_12665 5c6c998d545d406771539b0be51a76e2 478 Gene3D G3DSA:3.40.309.10 253 447 4.2E-147 T 31-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 DFR85_04055 698775a78606ff1a2ee1f8c38e51bfd0 260 PIRSF PIRSF000097 2 260 2.9E-46 T 31-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 DFR85_04055 698775a78606ff1a2ee1f8c38e51bfd0 260 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 128 145 - T 31-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 DFR85_04055 698775a78606ff1a2ee1f8c38e51bfd0 260 SUPERFAMILY SSF51430 5 259 6.81E-87 T 31-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily DFR85_04055 698775a78606ff1a2ee1f8c38e51bfd0 260 PRINTS PR00069 Aldo-keto reductase signature 97 115 6.4E-30 T 31-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 DFR85_04055 698775a78606ff1a2ee1f8c38e51bfd0 260 PRINTS PR00069 Aldo-keto reductase signature 199 223 6.4E-30 T 31-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 DFR85_04055 698775a78606ff1a2ee1f8c38e51bfd0 260 PRINTS PR00069 Aldo-keto reductase signature 40 64 6.4E-30 T 31-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 DFR85_04055 698775a78606ff1a2ee1f8c38e51bfd0 260 PRINTS PR00069 Aldo-keto reductase signature 162 191 6.4E-30 T 31-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 DFR85_04055 698775a78606ff1a2ee1f8c38e51bfd0 260 PRINTS PR00069 Aldo-keto reductase signature 128 145 6.4E-30 T 31-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 DFR85_04055 698775a78606ff1a2ee1f8c38e51bfd0 260 Gene3D G3DSA:3.20.20.100 2 260 5.4E-94 T 31-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily DFR85_04055 698775a78606ff1a2ee1f8c38e51bfd0 260 Pfam PF00248 Aldo/keto reductase family 10 259 1.4E-70 T 31-10-2018 IPR023210 NADP-dependent oxidoreductase domain DFR85_06310 a68fa0994243cb2089db6cf5aba700a0 765 Gene3D G3DSA:3.40.50.12320 224 397 2.5E-23 T 31-10-2018 DFR85_06310 a68fa0994243cb2089db6cf5aba700a0 765 Pfam PF08351 Domain of unknown function (DUF1726) 84 169 4.4E-25 T 31-10-2018 IPR013562 tRNA(Met) cytidine acetyltransferase TmcA, N-terminal Reactome: R-HSA-6790901 DFR85_06310 a68fa0994243cb2089db6cf5aba700a0 765 Pfam PF05127 Helicase 229 407 1.7E-45 T 31-10-2018 IPR007807 Helicase domain Reactome: R-HSA-6790901 DFR85_06310 a68fa0994243cb2089db6cf5aba700a0 765 SUPERFAMILY SSF52540 30 352 1.2E-9 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_06310 a68fa0994243cb2089db6cf5aba700a0 765 SUPERFAMILY SSF55729 446 591 7.75E-10 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase DFR85_06310 a68fa0994243cb2089db6cf5aba700a0 765 Pfam PF13718 GNAT acetyltransferase 2 440 556 1.2E-25 T 31-10-2018 IPR000182 GNAT domain DFR85_06310 a68fa0994243cb2089db6cf5aba700a0 765 Gene3D G3DSA:3.40.630.30 400 603 4.6E-50 T 31-10-2018 DFR85_06310 a68fa0994243cb2089db6cf5aba700a0 765 Hamap MF_01886 tRNA(Met) cytidine acetyltransferase TmcA [tmcA]. 22 745 40.819 T 31-10-2018 IPR024914 tRNA(Met) cytidine acetyltransferase TmcA GO:0000049|GO:0002101|GO:0051391|GO:0051392 DFR85_08305 e83f8b642d96ccb1e5a8fa450485c3db 163 Hamap MF_01117 CDP-archaeol synthase [carS]. 11 163 25.146 T 31-10-2018 IPR002726 CDP-archaeol synthase, archaea KEGG: 00564+2.7.7.67|MetaCyc: PWY-6349 DFR85_08305 e83f8b642d96ccb1e5a8fa450485c3db 163 Pfam PF01864 CDP-archaeol synthase 6 163 5.4E-37 T 31-10-2018 IPR032690 CDP-archaeol synthase KEGG: 00564+2.7.7.67|MetaCyc: PWY-6349 DFR85_00885 badd3344a4b7e237375221d3e342d9f7 279 Pfam PF01380 SIS domain 31 141 3.0E-7 T 31-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 DFR85_00885 badd3344a4b7e237375221d3e342d9f7 279 SUPERFAMILY SSF53697 13 224 1.64E-24 T 31-10-2018 DFR85_00885 badd3344a4b7e237375221d3e342d9f7 279 Gene3D G3DSA:3.40.50.10490 153 256 2.9E-7 T 31-10-2018 DFR85_00885 badd3344a4b7e237375221d3e342d9f7 279 Gene3D G3DSA:3.40.50.10490 3 152 5.3E-15 T 31-10-2018 DFR85_05520 afc6ca9f85cdbae9956b49e901911651 375 Pfam PF07690 Major Facilitator Superfamily 13 343 9.1E-32 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_05520 afc6ca9f85cdbae9956b49e901911651 375 SUPERFAMILY SSF103473 7 357 8.5E-47 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_05520 afc6ca9f85cdbae9956b49e901911651 375 Gene3D G3DSA:1.20.1250.20 187 375 4.5E-13 T 31-10-2018 DFR85_05520 afc6ca9f85cdbae9956b49e901911651 375 Gene3D G3DSA:1.20.1250.20 3 186 3.8E-33 T 31-10-2018 DFR85_06415 6f3e0c59631bc442f02a982ce6793088 338 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 24 121 4.0E-26 T 31-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DFR85_06415 6f3e0c59631bc442f02a982ce6793088 338 SUPERFAMILY SSF51735 133 305 7.38E-37 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_06415 6f3e0c59631bc442f02a982ce6793088 338 SMART SM00829 9 336 2.9E-4 T 31-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DFR85_06415 6f3e0c59631bc442f02a982ce6793088 338 Gene3D G3DSA:3.90.180.10 15 328 1.8E-91 T 31-10-2018 DFR85_06415 6f3e0c59631bc442f02a982ce6793088 338 Pfam PF00107 Zinc-binding dehydrogenase 170 300 8.8E-25 T 31-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DFR85_06415 6f3e0c59631bc442f02a982ce6793088 338 Gene3D G3DSA:3.40.50.720 148 284 1.8E-91 T 31-10-2018 DFR85_06415 6f3e0c59631bc442f02a982ce6793088 338 SUPERFAMILY SSF50129 1 336 5.33E-40 T 31-10-2018 IPR011032 GroES-like superfamily DFR85_00580 d95f64947666ec154d9c3ea6803e7722 60 ProDom PD010328 DNA-BINDING METHYLATION DIRECT SEQUENCING 3D-STRUCTURE A 7A 3.1.27.- P2 7D 9 60 3.0E-12 T 31-10-2018 IPR003212 DNA-binding 7kDa protein GO:0003677|GO:0004521 DFR85_00580 d95f64947666ec154d9c3ea6803e7722 60 SUPERFAMILY SSF54160 1 60 1.51E-32 T 31-10-2018 IPR016197 Chromo-like domain superfamily DFR85_00580 d95f64947666ec154d9c3ea6803e7722 60 Gene3D G3DSA:2.40.50.40 1 60 3.3E-35 T 31-10-2018 DFR85_00580 d95f64947666ec154d9c3ea6803e7722 60 Pfam PF02294 7kD DNA-binding domain 3 60 8.0E-39 T 31-10-2018 IPR003212 DNA-binding 7kDa protein GO:0003677|GO:0004521 DFR85_08720 07211cf7a1e60f4abd4f3b99c07cbb40 297 Gene3D G3DSA:3.90.230.10 11 288 4.3E-93 T 31-10-2018 DFR85_08720 07211cf7a1e60f4abd4f3b99c07cbb40 297 Hamap MF_01975 Methionine aminopeptidase [map]. 6 297 44.598 T 31-10-2018 IPR028595 Methionine aminopeptidase, archaeal GO:0004177|GO:0006508 MetaCyc: PWY-7799|MetaCyc: PWY-7800 DFR85_08720 07211cf7a1e60f4abd4f3b99c07cbb40 297 SUPERFAMILY SSF46785 197 273 4.08E-12 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_08720 07211cf7a1e60f4abd4f3b99c07cbb40 297 PRINTS PR00599 Methionine aminopeptidase-1 signature 147 159 8.4E-10 T 31-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 DFR85_08720 07211cf7a1e60f4abd4f3b99c07cbb40 297 PRINTS PR00599 Methionine aminopeptidase-1 signature 178 190 8.4E-10 T 31-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 DFR85_08720 07211cf7a1e60f4abd4f3b99c07cbb40 297 PRINTS PR00599 Methionine aminopeptidase-1 signature 55 68 8.4E-10 T 31-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 DFR85_08720 07211cf7a1e60f4abd4f3b99c07cbb40 297 PRINTS PR00599 Methionine aminopeptidase-1 signature 80 96 8.4E-10 T 31-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 DFR85_08720 07211cf7a1e60f4abd4f3b99c07cbb40 297 TIGRFAM TIGR00501 met_pdase_II: methionine aminopeptidase, type II 9 297 2.5E-98 T 31-10-2018 IPR002468 Peptidase M24A, methionine aminopeptidase, subfamily 2 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800|Reactome: R-HSA-2514859 DFR85_08720 07211cf7a1e60f4abd4f3b99c07cbb40 297 Gene3D G3DSA:1.10.10.10 197 274 4.3E-93 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_08720 07211cf7a1e60f4abd4f3b99c07cbb40 297 SUPERFAMILY SSF55920 2 297 2.75E-59 T 31-10-2018 IPR036005 Creatinase/aminopeptidase-like DFR85_08720 07211cf7a1e60f4abd4f3b99c07cbb40 297 Pfam PF00557 Metallopeptidase family M24 9 289 3.2E-36 T 31-10-2018 IPR000994 Peptidase M24 DFR85_08015 0157c378bfdd0e48b6c6a82b1510a402 324 SUPERFAMILY SSF51430 1 307 1.2E-58 T 31-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily DFR85_08015 0157c378bfdd0e48b6c6a82b1510a402 324 Pfam PF00248 Aldo/keto reductase family 15 304 1.5E-44 T 31-10-2018 IPR023210 NADP-dependent oxidoreductase domain DFR85_08015 0157c378bfdd0e48b6c6a82b1510a402 324 Gene3D G3DSA:3.20.20.100 1 307 1.4E-57 T 31-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily DFR85_08015 0157c378bfdd0e48b6c6a82b1510a402 324 PRINTS PR00069 Aldo-keto reductase signature 237 261 1.2E-5 T 31-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 DFR85_08015 0157c378bfdd0e48b6c6a82b1510a402 324 PRINTS PR00069 Aldo-keto reductase signature 140 157 1.2E-5 T 31-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 DFR85_08015 0157c378bfdd0e48b6c6a82b1510a402 324 PRINTS PR00069 Aldo-keto reductase signature 108 126 1.2E-5 T 31-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 DFR85_10505 031a0d1352bc6f158d58ae88005fbd56 321 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 118 293 4.2E-48 T 31-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 DFR85_10505 031a0d1352bc6f158d58ae88005fbd56 321 SUPERFAMILY SSF52283 15 142 6.05E-33 T 31-10-2018 DFR85_10505 031a0d1352bc6f158d58ae88005fbd56 321 SMART SM00997 127 286 0.0047 T 31-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 DFR85_10505 031a0d1352bc6f158d58ae88005fbd56 321 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 16 317 3.8E-36 T 31-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 DFR85_10505 031a0d1352bc6f158d58ae88005fbd56 321 Gene3D G3DSA:3.40.50.720 17 310 1.9E-109 T 31-10-2018 DFR85_10505 031a0d1352bc6f158d58ae88005fbd56 321 Gene3D G3DSA:3.40.50.720 105 295 1.9E-109 T 31-10-2018 DFR85_10505 031a0d1352bc6f158d58ae88005fbd56 321 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 153 180 - T 31-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 DFR85_10505 031a0d1352bc6f158d58ae88005fbd56 321 SUPERFAMILY SSF51735 110 294 4.13E-45 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_11835 3ca729e86715d1a54eee9e34130a273a 135 SUPERFAMILY SSF82784 2 133 1.83E-24 T 31-10-2018 IPR036102 OsmC/Ohr superfamily DFR85_11835 3ca729e86715d1a54eee9e34130a273a 135 Gene3D G3DSA:3.30.300.20 1 122 1.9E-21 T 31-10-2018 IPR015946 K homology domain-like, alpha/beta DFR85_11835 3ca729e86715d1a54eee9e34130a273a 135 Pfam PF02566 OsmC-like protein 31 130 4.0E-19 T 31-10-2018 IPR003718 OsmC/Ohr family DFR85_02510 65da9d386e5ef10e617cf10145a16159 218 Pfam PF00699 Urease beta subunit 120 199 1.5E-34 T 31-10-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 DFR85_02510 65da9d386e5ef10e617cf10145a16159 218 TIGRFAM TIGR00192 urease_beta: urease, beta subunit 112 202 3.7E-32 T 31-10-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 DFR85_02510 65da9d386e5ef10e617cf10145a16159 218 Gene3D G3DSA:2.10.150.10 111 218 7.8E-41 T 31-10-2018 IPR036461 Urease, beta subunit superfamily KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 DFR85_02510 65da9d386e5ef10e617cf10145a16159 218 Gene3D G3DSA:3.30.280.10 4 110 7.1E-40 T 31-10-2018 IPR036463 Urease, gamma subunit superfamily GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 DFR85_02510 65da9d386e5ef10e617cf10145a16159 218 PIRSF PIRSF001225 1 218 3.7E-89 T 31-10-2018 IPR008223 Urease, gamma-beta subunit GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 DFR85_02510 65da9d386e5ef10e617cf10145a16159 218 Pfam PF00547 Urease, gamma subunit 1 99 1.6E-38 T 31-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 DFR85_02510 65da9d386e5ef10e617cf10145a16159 218 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 9 99 7.0E-37 T 31-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 DFR85_02510 65da9d386e5ef10e617cf10145a16159 218 SUPERFAMILY SSF51278 115 217 2.49E-37 T 31-10-2018 IPR036461 Urease, beta subunit superfamily KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 DFR85_02510 65da9d386e5ef10e617cf10145a16159 218 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 1 101 2.7E-42 T 31-10-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 DFR85_02510 65da9d386e5ef10e617cf10145a16159 218 SUPERFAMILY SSF54111 1 103 1.44E-38 T 31-10-2018 IPR036463 Urease, gamma subunit superfamily GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 DFR85_06820 00ff95baa7b98ac1e88089dd8e5a7788 101 Gene3D G3DSA:1.10.10.10 1 89 6.4E-14 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_06820 00ff95baa7b98ac1e88089dd8e5a7788 101 SUPERFAMILY SSF46785 6 77 2.01E-17 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_06820 00ff95baa7b98ac1e88089dd8e5a7788 101 Pfam PF01022 Bacterial regulatory protein, arsR family 22 65 1.1E-12 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DFR85_06820 00ff95baa7b98ac1e88089dd8e5a7788 101 SMART SM00418 13 92 5.3E-4 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DFR85_03440 7b2dd4071878415d6655a5549265d5f6 315 PIRSF PIRSF037420 6 300 2.8E-34 T 31-10-2018 IPR017200 Coenzyme PQQ synthesis protein E DFR85_03440 7b2dd4071878415d6655a5549265d5f6 315 SUPERFAMILY SSF102114 10 280 4.97E-46 T 31-10-2018 DFR85_03440 7b2dd4071878415d6655a5549265d5f6 315 Pfam PF04055 Radical SAM superfamily 18 154 3.4E-19 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR85_03440 7b2dd4071878415d6655a5549265d5f6 315 Pfam PF13353 4Fe-4S single cluster domain 19 128 1.3E-6 T 31-10-2018 DFR85_03440 7b2dd4071878415d6655a5549265d5f6 315 Gene3D G3DSA:3.20.20.70 6 300 5.5E-42 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_13520 66f219d3efc5149e694022d019fe82e6 195 Pfam PF03787 RAMP superfamily 25 165 1.7E-9 T 31-10-2018 IPR005537 CRISPR type III-associated RAMP protein DFR85_01010 dc410ab4c9296b2b1289a848a180c9f4 154 Pfam PF09821 C-terminal AAA-associated domain 31 145 2.6E-28 T 31-10-2018 IPR018632 C-terminal AAA-associated domain DFR85_09055 a431518df402e5ae2b0dde01fe2a4108 383 Gene3D G3DSA:3.90.105.10 24 168 3.9E-68 T 31-10-2018 DFR85_09055 a431518df402e5ae2b0dde01fe2a4108 383 Pfam PF03453 MoeA N-terminal region (domain I and II) 3 158 2.0E-32 T 31-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 DFR85_09055 a431518df402e5ae2b0dde01fe2a4108 383 Pfam PF00994 Probable molybdopterin binding domain 173 299 9.6E-14 T 31-10-2018 IPR001453 MoaB/Mog domain DFR85_09055 a431518df402e5ae2b0dde01fe2a4108 383 SMART SM00852 173 306 4.0E-23 T 31-10-2018 IPR001453 MoaB/Mog domain DFR85_09055 a431518df402e5ae2b0dde01fe2a4108 383 SUPERFAMILY SSF53218 171 309 4.45E-22 T 31-10-2018 IPR036425 MoaB/Mog-like domain superfamily DFR85_09055 a431518df402e5ae2b0dde01fe2a4108 383 Gene3D G3DSA:2.170.190.11 46 135 3.9E-68 T 31-10-2018 DFR85_09055 a431518df402e5ae2b0dde01fe2a4108 383 SUPERFAMILY SSF63882 2 168 4.71E-39 T 31-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 DFR85_09055 a431518df402e5ae2b0dde01fe2a4108 383 Gene3D G3DSA:3.40.980.10 169 313 3.9E-68 T 31-10-2018 IPR036425 MoaB/Mog-like domain superfamily DFR85_09055 a431518df402e5ae2b0dde01fe2a4108 383 Gene3D G3DSA:2.40.340.10 314 375 3.9E-68 T 31-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 DFR85_00830 47b006656698b55cb27918ef08af953c 170 TIGRFAM TIGR00340 zpr1_rel: zinc finger protein ZPR1 homolog 13 162 2.0E-44 T 31-10-2018 IPR004470 Zinc finger, ZPR1-type, subgroup GO:0008270 DFR85_00830 47b006656698b55cb27918ef08af953c 170 Pfam PF03367 ZPR1 zinc-finger domain 12 154 8.2E-30 T 31-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 DFR85_00830 47b006656698b55cb27918ef08af953c 170 Gene3D G3DSA:2.60.120.1040 59 166 2.9E-18 T 31-10-2018 DFR85_00830 47b006656698b55cb27918ef08af953c 170 TIGRFAM TIGR00310 ZPR1_znf: ZPR1 zinc finger domain 12 160 6.4E-30 T 31-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 DFR85_00830 47b006656698b55cb27918ef08af953c 170 SMART SM00709 11 156 4.4E-33 T 31-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 DFR85_15730 c7f3b82dd9915829649886ea6339e9e1 772 SUPERFAMILY SSF56003 124 770 1.83E-137 T 31-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 DFR85_15730 c7f3b82dd9915829649886ea6339e9e1 772 Gene3D G3DSA:3.30.365.10 359 765 1.9E-84 T 31-10-2018 DFR85_15730 c7f3b82dd9915829649886ea6339e9e1 772 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 138 706 4.5E-126 T 31-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DFR85_15730 c7f3b82dd9915829649886ea6339e9e1 772 SMART SM01008 13 123 2.5E-15 T 31-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DFR85_15730 c7f3b82dd9915829649886ea6339e9e1 772 Gene3D G3DSA:3.90.1170.50 29 123 3.7E-73 T 31-10-2018 DFR85_15730 c7f3b82dd9915829649886ea6339e9e1 772 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 14 120 6.2E-10 T 31-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DFR85_15730 c7f3b82dd9915829649886ea6339e9e1 772 Gene3D G3DSA:3.30.365.10 440 623 1.9E-84 T 31-10-2018 DFR85_15730 c7f3b82dd9915829649886ea6339e9e1 772 Gene3D G3DSA:3.30.365.10 12 271 3.7E-73 T 31-10-2018 DFR85_15730 c7f3b82dd9915829649886ea6339e9e1 772 Gene3D G3DSA:3.30.365.10 124 348 3.7E-73 T 31-10-2018 DFR85_15730 c7f3b82dd9915829649886ea6339e9e1 772 SUPERFAMILY SSF54665 6 127 1.83E-24 T 31-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily DFR85_15680 a00d76b602bc5fbf39b2b462959c34d4 111 SUPERFAMILY SSF46785 5 82 1.99E-25 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_15680 a00d76b602bc5fbf39b2b462959c34d4 111 Pfam PF01022 Bacterial regulatory protein, arsR family 17 62 2.4E-19 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DFR85_15680 a00d76b602bc5fbf39b2b462959c34d4 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 12 27 6.3E-18 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DFR85_15680 a00d76b602bc5fbf39b2b462959c34d4 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 44 59 6.3E-18 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DFR85_15680 a00d76b602bc5fbf39b2b462959c34d4 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 74 6.3E-18 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DFR85_15680 a00d76b602bc5fbf39b2b462959c34d4 111 Gene3D G3DSA:1.10.10.10 1 96 2.5E-29 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_15680 a00d76b602bc5fbf39b2b462959c34d4 111 SMART SM00418 10 88 4.9E-30 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DFR85_10380 d18122dd9bb89e2f524a20a8ac4f26a4 244 SUPERFAMILY SSF52402 3 194 2.21E-35 T 31-10-2018 DFR85_10380 d18122dd9bb89e2f524a20a8ac4f26a4 244 Gene3D G3DSA:3.40.50.620 2 190 5.0E-34 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR85_10380 d18122dd9bb89e2f524a20a8ac4f26a4 244 Pfam PF06508 Queuosine biosynthesis protein QueC 5 65 1.3E-7 T 31-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 DFR85_10380 d18122dd9bb89e2f524a20a8ac4f26a4 244 Pfam PF06508 Queuosine biosynthesis protein QueC 94 183 1.5E-14 T 31-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 DFR85_07655 aa3cd482cd08693437b85fe0d1f2f5f2 332 Hamap MF_01163 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase [purP]. 1 332 49.632 T 31-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 DFR85_07655 aa3cd482cd08693437b85fe0d1f2f5f2 332 SUPERFAMILY SSF52440 3 101 1.53E-32 T 31-10-2018 IPR016185 Pre-ATP-grasp domain superfamily DFR85_07655 aa3cd482cd08693437b85fe0d1f2f5f2 332 Gene3D G3DSA:3.30.1490.20 117 178 2.8E-91 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 DFR85_07655 aa3cd482cd08693437b85fe0d1f2f5f2 332 Pfam PF06849 Protein of unknown function (DUF1246) 3 120 4.2E-43 T 31-10-2018 IPR010672 IMP biosynthesis enzyme PurP, N-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 DFR85_07655 aa3cd482cd08693437b85fe0d1f2f5f2 332 Gene3D G3DSA:3.30.470.20 89 329 2.8E-91 T 31-10-2018 DFR85_07655 aa3cd482cd08693437b85fe0d1f2f5f2 332 Pfam PF06973 Domain of unknown function (DUF1297) 152 332 8.8E-72 T 31-10-2018 IPR009720 IMP biosynthesis enzyme PurP, C-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 DFR85_07655 aa3cd482cd08693437b85fe0d1f2f5f2 332 SUPERFAMILY SSF56059 104 332 6.86E-78 T 31-10-2018 DFR85_07655 aa3cd482cd08693437b85fe0d1f2f5f2 332 Gene3D G3DSA:3.40.50.20 1 88 6.1E-28 T 31-10-2018 DFR85_07655 aa3cd482cd08693437b85fe0d1f2f5f2 332 PIRSF PIRSF004602 1 332 1.7E-132 T 31-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 DFR85_02420 d72555fe1840876b3668dc4e7e233e1e 98 Gene3D G3DSA:3.30.460.10 2 93 3.0E-14 T 31-10-2018 DFR85_02420 d72555fe1840876b3668dc4e7e233e1e 98 SUPERFAMILY SSF81301 4 92 2.77E-15 T 31-10-2018 DFR85_02420 d72555fe1840876b3668dc4e7e233e1e 98 Pfam PF01909 Nucleotidyltransferase domain 7 85 8.9E-10 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 DFR85_02405 68b1b51f3940a1925abd280e7a91515e 125 Gene3D G3DSA:1.20.120.330 1 123 4.1E-36 T 31-10-2018 DFR85_02405 68b1b51f3940a1925abd280e7a91515e 125 Pfam PF05942 Archaeal PaREP1/PaREP8 family 6 111 2.9E-26 T 31-10-2018 IPR010268 Archaeal PaREP1 DFR85_10215 2e9665c40e47f9d73d0beff02f42a2e4 361 Pfam PF00108 Thiolase, N-terminal domain 17 157 1.5E-7 T 31-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 DFR85_10215 2e9665c40e47f9d73d0beff02f42a2e4 361 SUPERFAMILY SSF53901 6 226 4.43E-22 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR85_10215 2e9665c40e47f9d73d0beff02f42a2e4 361 SUPERFAMILY SSF53901 245 339 4.03E-14 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR85_10215 2e9665c40e47f9d73d0beff02f42a2e4 361 Gene3D G3DSA:3.40.47.10 2 359 3.0E-61 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR85_10215 2e9665c40e47f9d73d0beff02f42a2e4 361 PIRSF PIRSF000429 9 347 7.3E-28 T 31-10-2018 IPR002155 Thiolase GO:0016747 DFR85_07080 ee4d79cb8d5adf4966386562af6949d1 156 SUPERFAMILY SSF54843 9 155 1.96E-50 T 31-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 DFR85_07080 ee4d79cb8d5adf4966386562af6949d1 156 Gene3D G3DSA:3.90.470.10 5 156 6.0E-55 T 31-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 DFR85_07080 ee4d79cb8d5adf4966386562af6949d1 156 Hamap MF_01331_A 50S ribosomal protein L22 [rplV]. 2 156 32.213 T 31-10-2018 IPR005721 Ribosomal protein L22/L17, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07080 ee4d79cb8d5adf4966386562af6949d1 156 Pfam PF00237 Ribosomal protein L22p/L17e 19 153 1.6E-34 T 31-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 DFR85_07080 ee4d79cb8d5adf4966386562af6949d1 156 ProSitePatterns PS00464 Ribosomal protein L22 signature. 129 153 - T 31-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07080 ee4d79cb8d5adf4966386562af6949d1 156 TIGRFAM TIGR01038 uL22_arch_euk: ribosomal protein uL22 8 155 1.7E-56 T 31-10-2018 IPR005721 Ribosomal protein L22/L17, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_09955 04b8d2d263b1a87d1bc915057dee7d67 587 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 587 6.7E-193 T 31-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 DFR85_09955 04b8d2d263b1a87d1bc915057dee7d67 587 Gene3D G3DSA:3.40.50.10490 252 586 7.5E-105 T 31-10-2018 DFR85_09955 04b8d2d263b1a87d1bc915057dee7d67 587 Pfam PF13522 Glutamine amidotransferase domain 63 176 3.6E-19 T 31-10-2018 DFR85_09955 04b8d2d263b1a87d1bc915057dee7d67 587 Gene3D G3DSA:3.40.50.10490 430 572 7.5E-105 T 31-10-2018 DFR85_09955 04b8d2d263b1a87d1bc915057dee7d67 587 Gene3D G3DSA:3.60.20.10 2 237 1.8E-67 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR85_09955 04b8d2d263b1a87d1bc915057dee7d67 587 Pfam PF01380 SIS domain 444 568 5.9E-19 T 31-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 DFR85_09955 04b8d2d263b1a87d1bc915057dee7d67 587 Pfam PF01380 SIS domain 288 408 5.7E-26 T 31-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 DFR85_09955 04b8d2d263b1a87d1bc915057dee7d67 587 SUPERFAMILY SSF53697 256 586 1.86E-85 T 31-10-2018 DFR85_09955 04b8d2d263b1a87d1bc915057dee7d67 587 SUPERFAMILY SSF56235 2 227 2.83E-65 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR85_15285 5dac00c41a4e934af7c8f3a3bf9c1b89 601 PIRSF PIRSF006439 1 591 5.1E-197 T 31-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 DFR85_15285 5dac00c41a4e934af7c8f3a3bf9c1b89 601 TIGRFAM TIGR03336 IOR_alpha: indolepyruvate ferredoxin oxidoreductase, alpha subunit 3 585 1.6E-196 T 31-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 DFR85_15285 5dac00c41a4e934af7c8f3a3bf9c1b89 601 Gene3D G3DSA:3.40.50.970 367 508 1.7E-13 T 31-10-2018 DFR85_15285 5dac00c41a4e934af7c8f3a3bf9c1b89 601 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 378 509 2.8E-18 T 31-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 DFR85_15285 5dac00c41a4e934af7c8f3a3bf9c1b89 601 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 15 180 9.1E-12 T 31-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 DFR85_15285 5dac00c41a4e934af7c8f3a3bf9c1b89 601 SUPERFAMILY SSF52922 225 282 7.4E-5 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 DFR85_15285 5dac00c41a4e934af7c8f3a3bf9c1b89 601 SUPERFAMILY SSF52518 1 207 2.4E-53 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR85_15285 5dac00c41a4e934af7c8f3a3bf9c1b89 601 Pfam PF00037 4Fe-4S binding domain 564 586 3.3E-8 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR85_15285 5dac00c41a4e934af7c8f3a3bf9c1b89 601 Gene3D G3DSA:3.30.70.20 509 596 7.5E-11 T 31-10-2018 DFR85_15285 5dac00c41a4e934af7c8f3a3bf9c1b89 601 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 570 581 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR85_15285 5dac00c41a4e934af7c8f3a3bf9c1b89 601 SUPERFAMILY SSF54862 517 591 3.03E-17 T 31-10-2018 DFR85_15285 5dac00c41a4e934af7c8f3a3bf9c1b89 601 SUPERFAMILY SSF52518 343 514 6.79E-25 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR85_15285 5dac00c41a4e934af7c8f3a3bf9c1b89 601 Gene3D G3DSA:3.40.50.970 1 178 5.0E-48 T 31-10-2018 DFR85_15590 ce4a86b2dadc63da002dc53591ede6c4 128 Pfam PF01850 PIN domain 5 122 2.2E-13 T 31-10-2018 IPR002716 PIN domain DFR85_15590 ce4a86b2dadc63da002dc53591ede6c4 128 SUPERFAMILY SSF88723 5 122 7.29E-17 T 31-10-2018 IPR029060 PIN-like domain superfamily DFR85_15590 ce4a86b2dadc63da002dc53591ede6c4 128 Gene3D G3DSA:3.40.50.1010 5 128 1.5E-11 T 31-10-2018 DFR85_06120 21a6542bcb43380472e91bdcb3006221 537 Pfam PF03454 MoeA C-terminal region (domain IV) 330 396 2.2E-5 T 31-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 DFR85_06120 21a6542bcb43380472e91bdcb3006221 537 ProSitePatterns PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 252 285 - T 31-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 DFR85_06120 21a6542bcb43380472e91bdcb3006221 537 Gene3D G3DSA:2.40.340.10 326 389 3.3E-99 T 31-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 DFR85_06120 21a6542bcb43380472e91bdcb3006221 537 SUPERFAMILY SSF63867 327 396 9.48E-6 T 31-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 DFR85_06120 21a6542bcb43380472e91bdcb3006221 537 Pfam PF03453 MoeA N-terminal region (domain I and II) 14 169 2.2E-34 T 31-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 DFR85_06120 21a6542bcb43380472e91bdcb3006221 537 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 178 310 2.5E-28 T 31-10-2018 IPR001453 MoaB/Mog domain DFR85_06120 21a6542bcb43380472e91bdcb3006221 537 Pfam PF00994 Probable molybdopterin binding domain 182 314 5.1E-22 T 31-10-2018 IPR001453 MoaB/Mog domain DFR85_06120 21a6542bcb43380472e91bdcb3006221 537 Gene3D G3DSA:3.90.105.10 32 176 3.3E-99 T 31-10-2018 DFR85_06120 21a6542bcb43380472e91bdcb3006221 537 SUPERFAMILY SSF63882 13 177 2.09E-44 T 31-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 DFR85_06120 21a6542bcb43380472e91bdcb3006221 537 Gene3D G3DSA:3.40.980.10 177 325 3.3E-99 T 31-10-2018 IPR036425 MoaB/Mog-like domain superfamily DFR85_06120 21a6542bcb43380472e91bdcb3006221 537 SMART SM00852 181 317 1.0E-30 T 31-10-2018 IPR001453 MoaB/Mog domain DFR85_06120 21a6542bcb43380472e91bdcb3006221 537 Gene3D G3DSA:2.170.190.11 54 143 3.3E-99 T 31-10-2018 DFR85_06120 21a6542bcb43380472e91bdcb3006221 537 SUPERFAMILY SSF53218 178 318 4.06E-35 T 31-10-2018 IPR036425 MoaB/Mog-like domain superfamily DFR85_01565 0c9d4884c6798b32b5824065fc7a63dc 355 Gene3D G3DSA:3.30.360.10 150 332 3.1E-131 T 31-10-2018 DFR85_01565 0c9d4884c6798b32b5824065fc7a63dc 355 PIRSF PIRSF000148 4 354 3.9E-81 T 31-10-2018 DFR85_01565 0c9d4884c6798b32b5824065fc7a63dc 355 TIGRFAM TIGR00978 asd_EA: aspartate-semialdehyde dehydrogenase 5 349 2.9E-107 T 31-10-2018 IPR005676 Aspartate-semialdehyde dehydrogenase, peptidoglycan lacking GO:0050661|GO:0055114 DFR85_01565 0c9d4884c6798b32b5824065fc7a63dc 355 SUPERFAMILY SSF55347 148 336 6.25E-34 T 31-10-2018 DFR85_01565 0c9d4884c6798b32b5824065fc7a63dc 355 SMART SM00859 6 131 2.1E-32 T 31-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 DFR85_01565 0c9d4884c6798b32b5824065fc7a63dc 355 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 159 334 4.3E-20 T 31-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 DFR85_01565 0c9d4884c6798b32b5824065fc7a63dc 355 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 6 129 1.6E-30 T 31-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 DFR85_01565 0c9d4884c6798b32b5824065fc7a63dc 355 Gene3D G3DSA:3.40.50.720 6 352 3.1E-131 T 31-10-2018 DFR85_01565 0c9d4884c6798b32b5824065fc7a63dc 355 SUPERFAMILY SSF51735 5 177 1.42E-37 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_05770 fd65f92a4e69d92b59288c6afae8b01d 326 Pfam PF01497 Periplasmic binding protein 44 275 2.1E-19 T 31-10-2018 IPR002491 ABC transporter periplasmic binding domain DFR85_05770 fd65f92a4e69d92b59288c6afae8b01d 326 Gene3D G3DSA:3.40.50.1980 28 168 1.5E-16 T 31-10-2018 DFR85_05770 fd65f92a4e69d92b59288c6afae8b01d 326 Gene3D G3DSA:3.40.50.1980 170 303 9.0E-22 T 31-10-2018 DFR85_05770 fd65f92a4e69d92b59288c6afae8b01d 326 SUPERFAMILY SSF53807 36 292 9.42E-38 T 31-10-2018 DFR85_12910 10d1b10c2c22e84c0be91c85b09012cd 386 Gene3D G3DSA:3.60.21.10 217 377 9.1E-43 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like DFR85_12910 10d1b10c2c22e84c0be91c85b09012cd 386 Pfam PF00149 Calcineurin-like phosphoesterase 218 341 2.2E-6 T 31-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 DFR85_12910 10d1b10c2c22e84c0be91c85b09012cd 386 Gene3D G3DSA:3.90.1140.10 8 184 4.9E-6 T 31-10-2018 DFR85_12910 10d1b10c2c22e84c0be91c85b09012cd 386 SUPERFAMILY SSF56300 218 375 5.36E-16 T 31-10-2018 DFR85_12910 10d1b10c2c22e84c0be91c85b09012cd 386 Pfam PF13563 2'-5' RNA ligase superfamily 24 132 3.0E-9 T 31-10-2018 DFR85_13845 ffc51fe9a8bab8c874fa210ab0e77b3c 123 Gene3D G3DSA:2.40.50.140 57 123 4.0E-24 T 31-10-2018 DFR85_13845 ffc51fe9a8bab8c874fa210ab0e77b3c 123 Gene3D G3DSA:1.10.12.20 1 56 8.2E-19 T 31-10-2018 DFR85_13845 ffc51fe9a8bab8c874fa210ab0e77b3c 123 SUPERFAMILY SSF50249 3 112 5.48E-17 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR85_13845 ffc51fe9a8bab8c874fa210ab0e77b3c 123 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 18 49 3.0E-7 T 31-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal DFR85_07855 3e89898420856b1b2e455a1ab4a32fef 248 SUPERFAMILY SSF55979 128 248 6.28E-21 T 31-10-2018 DFR85_07855 3e89898420856b1b2e455a1ab4a32fef 248 SUPERFAMILY SSF55979 1 108 1.98E-22 T 31-10-2018 DFR85_07855 3e89898420856b1b2e455a1ab4a32fef 248 Hamap MF_00317 DNA polymerase sliding clamp [pcn]. 2 248 22.053 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 DFR85_07855 3e89898420856b1b2e455a1ab4a32fef 248 Pfam PF00705 Proliferating cell nuclear antigen, N-terminal domain 12 107 2.0E-6 T 31-10-2018 IPR022648 Proliferating cell nuclear antigen, PCNA, N-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 DFR85_07855 3e89898420856b1b2e455a1ab4a32fef 248 Gene3D G3DSA:3.70.10.10 1 243 2.8E-69 T 31-10-2018 DFR85_03720 a7f995fabf57d4a3bcd31c4d8eb6e011 142 Gene3D G3DSA:2.40.30.70 2 138 4.6E-35 T 31-10-2018 IPR036414 YaeB, N-terminal domain superfamily DFR85_03720 a7f995fabf57d4a3bcd31c4d8eb6e011 142 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 13 117 1.0E-35 T 31-10-2018 IPR023370 YaeB-like, N-terminal domain DFR85_03720 a7f995fabf57d4a3bcd31c4d8eb6e011 142 SUPERFAMILY SSF118196 2 135 6.41E-41 T 31-10-2018 IPR036413 YaeB-like superfamily DFR85_03720 a7f995fabf57d4a3bcd31c4d8eb6e011 142 Pfam PF01980 Uncharacterised protein family UPF0066 13 116 3.1E-33 T 31-10-2018 IPR023370 YaeB-like, N-terminal domain DFR85_12630 b9070fef8e2d98c1ce547d7ffd422376 215 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 57 7.4E-14 T 31-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DFR85_12630 b9070fef8e2d98c1ce547d7ffd422376 215 SMART SM00345 8 66 1.5E-9 T 31-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DFR85_12630 b9070fef8e2d98c1ce547d7ffd422376 215 Gene3D G3DSA:1.10.10.10 1 66 9.1E-19 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_12630 b9070fef8e2d98c1ce547d7ffd422376 215 Gene3D G3DSA:1.20.120.530 68 209 3.5E-29 T 31-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal DFR85_12630 b9070fef8e2d98c1ce547d7ffd422376 215 Pfam PF07729 FCD domain 76 198 1.4E-25 T 31-10-2018 IPR011711 GntR, C-terminal DFR85_12630 b9070fef8e2d98c1ce547d7ffd422376 215 SUPERFAMILY SSF48008 71 206 2.12E-25 T 31-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal DFR85_12630 b9070fef8e2d98c1ce547d7ffd422376 215 SUPERFAMILY SSF46785 4 70 2.26E-14 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_12630 b9070fef8e2d98c1ce547d7ffd422376 215 SMART SM00895 75 201 1.0E-20 T 31-10-2018 IPR011711 GntR, C-terminal DFR85_12630 b9070fef8e2d98c1ce547d7ffd422376 215 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 4.0E-5 T 31-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DFR85_12630 b9070fef8e2d98c1ce547d7ffd422376 215 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 4.0E-5 T 31-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 DFR85_01870 5433e8d28527d31df7d975c531792018 219 SUPERFAMILY SSF52540 1 201 2.66E-32 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_01870 5433e8d28527d31df7d975c531792018 219 Gene3D G3DSA:3.40.50.300 1 217 2.8E-37 T 31-10-2018 DFR85_01870 5433e8d28527d31df7d975c531792018 219 Pfam PF13614 AAA domain 2 148 2.1E-27 T 31-10-2018 IPR025669 AAA domain DFR85_13340 6b098967bf87b6fcd5773801ee437093 960 SUPERFAMILY SSF52540 167 610 1.99E-39 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_13340 6b098967bf87b6fcd5773801ee437093 960 Pfam PF00271 Helicase conserved C-terminal domain 537 608 1.6E-14 T 31-10-2018 IPR001650 Helicase, C-terminal DFR85_13340 6b098967bf87b6fcd5773801ee437093 960 SMART SM00490 527 609 7.9E-20 T 31-10-2018 IPR001650 Helicase, C-terminal DFR85_13340 6b098967bf87b6fcd5773801ee437093 960 Pfam PF00270 DEAD/DEAH box helicase 162 238 1.2E-7 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 DFR85_13340 6b098967bf87b6fcd5773801ee437093 960 Pfam PF00270 DEAD/DEAH box helicase 305 390 2.1E-6 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 DFR85_13340 6b098967bf87b6fcd5773801ee437093 960 SMART SM00487 155 419 2.3E-15 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain DFR85_09480 7189058f92427d27a33b0d66e738470c 319 Gene3D G3DSA:3.40.50.620 1 313 2.4E-62 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR85_09480 7189058f92427d27a33b0d66e738470c 319 SUPERFAMILY SSF52402 26 252 1.2E-33 T 31-10-2018 DFR85_09480 7189058f92427d27a33b0d66e738470c 319 TIGRFAM TIGR00269 TIGR00269: TIGR00269 family protein 201 307 3.1E-24 T 31-10-2018 IPR000541 Cytoplasmic tRNA 2-thiolation protein 1 GO:0000049|GO:0002098|GO:0034227 Reactome: R-HSA-6782315 DFR85_09480 7189058f92427d27a33b0d66e738470c 319 PIRSF PIRSF004976 1 315 1.5E-90 T 31-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 DFR85_09480 7189058f92427d27a33b0d66e738470c 319 Pfam PF01171 PP-loop family 49 186 5.1E-9 T 31-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 DFR85_06995 08c2922b24e29d52d39bf13f14b04e9e 143 Gene3D G3DSA:3.100.10.10 61 140 1.4E-14 T 31-10-2018 DFR85_06995 08c2922b24e29d52d39bf13f14b04e9e 143 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 30 139 2.2E-15 T 31-10-2018 IPR021131 Ribosomal protein L18e/L15P DFR85_06995 08c2922b24e29d52d39bf13f14b04e9e 143 Gene3D G3DSA:4.10.990.10 5 54 2.8E-5 T 31-10-2018 IPR027386 50S ribosomal protein L15, N-terminal DFR85_06995 08c2922b24e29d52d39bf13f14b04e9e 143 ProSitePatterns PS00475 Ribosomal protein L15 signature. 105 135 - T 31-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_06995 08c2922b24e29d52d39bf13f14b04e9e 143 SUPERFAMILY SSF52080 7 139 1.83E-28 T 31-10-2018 IPR036227 Ribosomal L18e/L15P superfamily DFR85_06995 08c2922b24e29d52d39bf13f14b04e9e 143 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 2 141 12.162 T 31-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 DFR85_07105 4e9ef13a919550abfccf889e8cd8398e 340 SUPERFAMILY SSF50447 4 340 1.06E-82 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily DFR85_07105 4e9ef13a919550abfccf889e8cd8398e 340 Gene3D G3DSA:4.10.960.10 9 260 6.3E-107 T 31-10-2018 DFR85_07105 4e9ef13a919550abfccf889e8cd8398e 340 Gene3D G3DSA:2.40.30.10 43 320 6.3E-107 T 31-10-2018 DFR85_07105 4e9ef13a919550abfccf889e8cd8398e 340 Hamap MF_01325_A 50S ribosomal protein L3 [rplC]. 1 339 44.364 T 31-10-2018 IPR019928 Ribosomal protein L3, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_07105 4e9ef13a919550abfccf889e8cd8398e 340 TIGRFAM TIGR03626 L3_arch: ribosomal protein uL3 8 338 3.2E-125 T 31-10-2018 IPR019928 Ribosomal protein L3, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_07105 4e9ef13a919550abfccf889e8cd8398e 340 Gene3D G3DSA:3.30.1430.10 82 193 6.3E-107 T 31-10-2018 DFR85_07105 4e9ef13a919550abfccf889e8cd8398e 340 ProSitePatterns PS00474 Ribosomal protein L3 signature. 198 221 - T 31-10-2018 IPR019926 Ribosomal protein L3, conserved site DFR85_07105 4e9ef13a919550abfccf889e8cd8398e 340 Pfam PF00297 Ribosomal protein L3 2 340 3.3E-67 T 31-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_01775 9f4ccf9353f2996ed6731bc10acdd1be 379 Gene3D G3DSA:3.40.50.150 93 361 2.0E-60 T 31-10-2018 DFR85_01775 9f4ccf9353f2996ed6731bc10acdd1be 379 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 155 169 8.5E-17 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase DFR85_01775 9f4ccf9353f2996ed6731bc10acdd1be 379 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 345 362 8.5E-17 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase DFR85_01775 9f4ccf9353f2996ed6731bc10acdd1be 379 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 184 194 8.5E-17 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase DFR85_01775 9f4ccf9353f2996ed6731bc10acdd1be 379 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 248 260 8.5E-17 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase DFR85_01775 9f4ccf9353f2996ed6731bc10acdd1be 379 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 295 311 8.5E-17 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase DFR85_01775 9f4ccf9353f2996ed6731bc10acdd1be 379 Pfam PF01189 16S rRNA methyltransferase RsmB/F 173 360 8.9E-36 T 31-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 DFR85_01775 9f4ccf9353f2996ed6731bc10acdd1be 379 SUPERFAMILY SSF53335 80 360 5.57E-50 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR85_12675 9a92fdb4e33eca3dad0cf31e960b52bc 328 SUPERFAMILY SSF51658 14 323 1.52E-54 T 31-10-2018 IPR036237 Xylose isomerase-like superfamily DFR85_12675 9a92fdb4e33eca3dad0cf31e960b52bc 328 Gene3D G3DSA:3.20.20.150 15 328 5.2E-91 T 31-10-2018 DFR85_12675 9a92fdb4e33eca3dad0cf31e960b52bc 328 PIRSF PIRSF016049 146 328 1.1E-65 T 31-10-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 DFR85_12675 9a92fdb4e33eca3dad0cf31e960b52bc 328 PIRSF PIRSF016049 3 151 4.8E-25 T 31-10-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 DFR85_12675 9a92fdb4e33eca3dad0cf31e960b52bc 328 Pfam PF03786 D-mannonate dehydratase (UxuA) 151 326 3.8E-62 T 31-10-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 DFR85_12675 9a92fdb4e33eca3dad0cf31e960b52bc 328 Pfam PF03786 D-mannonate dehydratase (UxuA) 1 146 7.4E-27 T 31-10-2018 IPR004628 Mannonate dehydratase GO:0006064|GO:0008927 KEGG: 00040+4.2.1.8|MetaCyc: PWY-7242 DFR85_05900 4c5882abc5140f15b1a2c2da19dc43bb 237 ProSitePatterns PS00211 ABC transporters family signature. 108 122 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DFR85_05900 4c5882abc5140f15b1a2c2da19dc43bb 237 SUPERFAMILY SSF52540 6 216 2.07E-56 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_05900 4c5882abc5140f15b1a2c2da19dc43bb 237 SMART SM00382 5 203 7.9E-16 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_05900 4c5882abc5140f15b1a2c2da19dc43bb 237 Gene3D G3DSA:3.40.50.300 2 232 1.5E-50 T 31-10-2018 DFR85_05900 4c5882abc5140f15b1a2c2da19dc43bb 237 Pfam PF00005 ABC transporter 5 135 3.1E-27 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR85_10350 38eeae607d9578c5616819df21fa5a25 243 Gene3D G3DSA:3.40.630.30 25 231 6.2E-21 T 31-10-2018 DFR85_10350 38eeae607d9578c5616819df21fa5a25 243 Pfam PF08445 FR47-like protein 148 234 3.7E-21 T 31-10-2018 IPR013653 FR47-like GO:0016747 DFR85_10350 38eeae607d9578c5616819df21fa5a25 243 SUPERFAMILY SSF55729 12 234 1.72E-24 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase DFR85_10925 2f51da406026187a117b6a046f7c5aa9 448 SUPERFAMILY SSF47364 3 87 8.77E-19 T 31-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 DFR85_10925 2f51da406026187a117b6a046f7c5aa9 448 Gene3D G3DSA:1.10.260.30 304 431 4.7E-43 T 31-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 DFR85_10925 2f51da406026187a117b6a046f7c5aa9 448 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 1 441 35.629 T 31-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 DFR85_10925 2f51da406026187a117b6a046f7c5aa9 448 SMART SM00963 1 82 4.3E-19 T 31-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 DFR85_10925 2f51da406026187a117b6a046f7c5aa9 448 SMART SM00382 95 298 7.9E-9 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_10925 2f51da406026187a117b6a046f7c5aa9 448 SMART SM00962 96 293 1.3E-95 T 31-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 DFR85_10925 2f51da406026187a117b6a046f7c5aa9 448 SUPERFAMILY SSF47446 295 430 4.19E-41 T 31-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 DFR85_10925 2f51da406026187a117b6a046f7c5aa9 448 Gene3D G3DSA:3.40.50.300 86 282 2.5E-108 T 31-10-2018 DFR85_10925 2f51da406026187a117b6a046f7c5aa9 448 Pfam PF02978 Signal peptide binding domain 327 426 9.7E-30 T 31-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 DFR85_10925 2f51da406026187a117b6a046f7c5aa9 448 Gene3D G3DSA:1.20.120.140 4 303 2.5E-108 T 31-10-2018 DFR85_10925 2f51da406026187a117b6a046f7c5aa9 448 Pfam PF02881 SRP54-type protein, helical bundle domain 3 78 4.2E-16 T 31-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 DFR85_10925 2f51da406026187a117b6a046f7c5aa9 448 SUPERFAMILY SSF52540 95 295 5.4E-50 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_10925 2f51da406026187a117b6a046f7c5aa9 448 Pfam PF00448 SRP54-type protein, GTPase domain 97 293 5.6E-70 T 31-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 DFR85_15205 26638403ac0a1a08caeb7d151d97fe4d 478 Pfam PF00324 Amino acid permease 17 463 1.0E-30 T 31-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 DFR85_15205 26638403ac0a1a08caeb7d151d97fe4d 478 Gene3D G3DSA:1.20.1740.10 5 469 2.8E-24 T 31-10-2018 DFR85_15205 26638403ac0a1a08caeb7d151d97fe4d 478 PIRSF PIRSF006060 1 477 6.8E-59 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_06185 66a8ba520b913176c462cdf9b75fde8a 376 Gene3D G3DSA:3.50.50.60 113 254 2.0E-91 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_06185 66a8ba520b913176c462cdf9b75fde8a 376 SUPERFAMILY SSF51905 118 245 6.11E-28 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_06185 66a8ba520b913176c462cdf9b75fde8a 376 Gene3D G3DSA:3.50.50.60 4 308 2.0E-91 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_06185 66a8ba520b913176c462cdf9b75fde8a 376 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 291 7.1E-14 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR85_06185 66a8ba520b913176c462cdf9b75fde8a 376 SUPERFAMILY SSF51905 2 314 1.34E-22 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_03410 2af28444320430fd7c79801d0f398114 178 Gene3D G3DSA:1.10.3480.10 5 176 5.0E-32 T 31-10-2018 DFR85_03410 2af28444320430fd7c79801d0f398114 178 SUPERFAMILY SSF89155 39 173 1.09E-29 T 31-10-2018 IPR036411 TorD-like superfamily DFR85_03410 2af28444320430fd7c79801d0f398114 178 Pfam PF02613 Nitrate reductase delta subunit 35 145 2.8E-22 T 31-10-2018 IPR020945 DMSO/Nitrate reductase chaperone DFR85_10240 3a13a6446406ef156f29611784a97ebc 339 Hamap MF_00559 Glyceraldehyde-3-phosphate dehydrogenase [gap]. 1 339 169.593 T 31-10-2018 IPR006436 Glyceraldehyde-3-phosphate dehydrogenase, type II GO:0005737|GO:0006096|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.59|KEGG: 00710+1.2.1.59 DFR85_10240 3a13a6446406ef156f29611784a97ebc 339 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 2 105 1.2E-11 T 31-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 DFR85_10240 3a13a6446406ef156f29611784a97ebc 339 TIGRFAM TIGR01546 GAPDH-II_archae: glyceraldehyde-3-phosphate dehydrogenase, type II 4 333 1.1E-153 T 31-10-2018 IPR006436 Glyceraldehyde-3-phosphate dehydrogenase, type II GO:0005737|GO:0006096|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.59|KEGG: 00710+1.2.1.59 DFR85_10240 3a13a6446406ef156f29611784a97ebc 339 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 137 144 - T 31-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR85_10240 3a13a6446406ef156f29611784a97ebc 339 Gene3D G3DSA:3.30.360.10 137 330 2.9E-138 T 31-10-2018 DFR85_10240 3a13a6446406ef156f29611784a97ebc 339 SMART SM00846 2 139 2.4E-13 T 31-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR85_10240 3a13a6446406ef156f29611784a97ebc 339 SUPERFAMILY SSF55347 139 300 3.43E-51 T 31-10-2018 DFR85_10240 3a13a6446406ef156f29611784a97ebc 339 PIRSF PIRSF000149 1 319 1.8E-76 T 31-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR85_10240 3a13a6446406ef156f29611784a97ebc 339 Gene3D G3DSA:3.40.50.720 4 326 2.9E-138 T 31-10-2018 DFR85_10240 3a13a6446406ef156f29611784a97ebc 339 SUPERFAMILY SSF51735 2 155 2.69E-43 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_10240 3a13a6446406ef156f29611784a97ebc 339 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 145 297 1.1E-20 T 31-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR85_01770 56b276e0ce13a60bf1af2b673db02ef8 354 Pfam PF09376 NurA domain 58 281 1.4E-12 T 31-10-2018 IPR018977 NurA domain DFR85_01770 56b276e0ce13a60bf1af2b673db02ef8 354 SMART SM00933 54 319 1.8E-12 T 31-10-2018 IPR018977 NurA domain DFR85_08710 a95f52e6a5070a45895676d532e30bdc 467 Pfam PF01409 tRNA synthetases class II core domain (F) 201 462 4.4E-83 T 31-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 DFR85_08710 a95f52e6a5070a45895676d532e30bdc 467 Hamap MF_00282 Phenylalanine--tRNA ligase alpha subunit [pheS]. 1 464 36.481 T 31-10-2018 IPR022917 Phenylalanine-tRNA ligase alpha subunit, bacterial/archaeal GO:0004826 KEGG: 00970+6.1.1.20 DFR85_08710 a95f52e6a5070a45895676d532e30bdc 467 Gene3D G3DSA:1.10.10.2310 14 199 3.7E-21 T 31-10-2018 DFR85_08710 a95f52e6a5070a45895676d532e30bdc 467 Gene3D G3DSA:1.10.10.2330 74 128 3.7E-21 T 31-10-2018 DFR85_08710 a95f52e6a5070a45895676d532e30bdc 467 SUPERFAMILY SSF46785 2 73 3.41E-7 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_08710 a95f52e6a5070a45895676d532e30bdc 467 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 153 464 4.6E-98 T 31-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 DFR85_08710 a95f52e6a5070a45895676d532e30bdc 467 Gene3D G3DSA:1.10.10.2320 61 158 3.7E-21 T 31-10-2018 DFR85_08710 a95f52e6a5070a45895676d532e30bdc 467 Gene3D G3DSA:3.30.930.10 216 466 6.3E-80 T 31-10-2018 DFR85_08710 a95f52e6a5070a45895676d532e30bdc 467 SUPERFAMILY SSF55681 201 463 8.0E-65 T 31-10-2018 DFR85_02290 e54636ba4a9790aa50f59a1e9ac41b56 348 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 145 347 6.9E-36 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 DFR85_02290 e54636ba4a9790aa50f59a1e9ac41b56 348 Gene3D G3DSA:1.10.3720.10 116 345 8.7E-16 T 31-10-2018 IPR035906 MetI-like superfamily DFR85_02290 e54636ba4a9790aa50f59a1e9ac41b56 348 SUPERFAMILY SSF161098 122 335 2.62E-11 T 31-10-2018 IPR035906 MetI-like superfamily DFR85_13205 e85a1d2b9447ee67b320ed4356750f76 533 SUPERFAMILY SSF160980 120 529 3.4E-57 T 31-10-2018 DFR85_13205 e85a1d2b9447ee67b320ed4356750f76 533 Pfam PF09455 CRISPR-associated (Cas) DxTHG family 122 504 4.5E-20 T 31-10-2018 IPR019016 CRISPR-associated DxTHG protein DFR85_13205 e85a1d2b9447ee67b320ed4356750f76 533 Gene3D G3DSA:3.40.50.10640 116 360 3.9E-41 T 31-10-2018 DFR85_13205 e85a1d2b9447ee67b320ed4356750f76 533 TIGRFAM TIGR01897 cas_MJ1666: CRISPR-associated protein, MJ1666 family 120 524 1.7E-47 T 31-10-2018 IPR010171 CRISPR-associated protein, MJ1666 DFR85_13205 e85a1d2b9447ee67b320ed4356750f76 533 Gene3D G3DSA:1.10.3740.10 396 533 2.2E-8 T 31-10-2018 IPR027419 CRISPR-associated protein Csx1, C-terminal DFR85_13205 e85a1d2b9447ee67b320ed4356750f76 533 TIGRFAM TIGR02549 CRISPR_DxTHG: CRISPR-associated DxTHG motif protein 249 269 2.4E-7 T 31-10-2018 IPR013383 CRISPR-associated protein DxTHG, conserved site DFR85_09450 ebb098df9cab56afc703e7d0caedc35b 228 Pfam PF00977 Histidine biosynthesis protein 3 222 2.0E-45 T 31-10-2018 IPR006062 Histidine biosynthesis GO:0000105 DFR85_09450 ebb098df9cab56afc703e7d0caedc35b 228 SUPERFAMILY SSF51366 1 220 1.08E-37 T 31-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 DFR85_09450 ebb098df9cab56afc703e7d0caedc35b 228 Gene3D G3DSA:3.20.20.70 1 224 9.1E-50 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_00615 f98eabb7011cd69081c3adb2a7fe60df 418 SMART SM00729 130 349 8.8E-51 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 DFR85_00615 f98eabb7011cd69081c3adb2a7fe60df 418 Gene3D G3DSA:3.80.30.20 129 363 1.6E-74 T 31-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe DFR85_00615 f98eabb7011cd69081c3adb2a7fe60df 418 SUPERFAMILY SSF102114 123 354 7.85E-47 T 31-10-2018 DFR85_00615 f98eabb7011cd69081c3adb2a7fe60df 418 TIGRFAM TIGR01578 MiaB-like-B: MiaB-like tRNA modifying enzyme, archaeal-type 2 418 3.6E-125 T 31-10-2018 IPR006466 MiaB-like tRNA modifying enzyme, archaeal-type Reactome: R-HSA-6782315 DFR85_00615 f98eabb7011cd69081c3adb2a7fe60df 418 Pfam PF00919 Uncharacterized protein family UPF0004 2 92 3.4E-20 T 31-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 DFR85_00615 f98eabb7011cd69081c3adb2a7fe60df 418 Pfam PF01938 TRAM domain 362 418 4.5E-7 T 31-10-2018 IPR002792 TRAM domain DFR85_00615 f98eabb7011cd69081c3adb2a7fe60df 418 Pfam PF04055 Radical SAM superfamily 134 308 1.9E-24 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR85_00615 f98eabb7011cd69081c3adb2a7fe60df 418 Gene3D G3DSA:3.40.50.12160 1 127 6.2E-22 T 31-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily DFR85_00615 f98eabb7011cd69081c3adb2a7fe60df 418 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 2 415 5.9E-126 T 31-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 DFR85_09485 b7b7f262e8377d246d0fc5e260ba0f58 93 Pfam PF02680 Uncharacterized ArCR, COG1888 3 89 1.2E-34 T 31-10-2018 IPR003831 Protein of unknown function DUF211 DFR85_09485 b7b7f262e8377d246d0fc5e260ba0f58 93 SUPERFAMILY SSF160363 2 91 4.97E-31 T 31-10-2018 IPR023129 MTH889-like domain superfamily DFR85_09485 b7b7f262e8377d246d0fc5e260ba0f58 93 Gene3D G3DSA:3.30.70.1340 1 86 4.3E-32 T 31-10-2018 IPR023129 MTH889-like domain superfamily DFR85_09485 b7b7f262e8377d246d0fc5e260ba0f58 93 ProDom PD012512 ARCHAEA PH1931 STS176 TA1183 MJ0319 PRECURSOR TVG0378908 UNCHARACTERIZED DUF211 AF1549 10 88 1.0E-26 T 31-10-2018 IPR003831 Protein of unknown function DUF211 DFR85_05345 846ff45d32727e1877ae658a11df3b53 346 Pfam PF00270 DEAD/DEAH box helicase 22 179 6.7E-39 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 DFR85_05345 846ff45d32727e1877ae658a11df3b53 346 SMART SM00487 17 201 6.1E-47 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain DFR85_05345 846ff45d32727e1877ae658a11df3b53 346 Pfam PF00271 Helicase conserved C-terminal domain 217 316 6.9E-30 T 31-10-2018 IPR001650 Helicase, C-terminal DFR85_05345 846ff45d32727e1877ae658a11df3b53 346 SUPERFAMILY SSF52540 60 336 4.2E-61 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_05345 846ff45d32727e1877ae658a11df3b53 346 Gene3D G3DSA:3.40.50.300 198 345 4.3E-50 T 31-10-2018 DFR85_05345 846ff45d32727e1877ae658a11df3b53 346 Gene3D G3DSA:3.40.50.300 2 193 1.5E-55 T 31-10-2018 DFR85_05345 846ff45d32727e1877ae658a11df3b53 346 SMART SM00490 236 316 1.7E-30 T 31-10-2018 IPR001650 Helicase, C-terminal DFR85_06690 6f2036dfabbba0ae5007c5c14cc01617 767 Gene3D G3DSA:1.10.8.60 358 451 1.4E-32 T 31-10-2018 DFR85_06690 6f2036dfabbba0ae5007c5c14cc01617 767 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 227 357 2.5E-48 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 DFR85_06690 6f2036dfabbba0ae5007c5c14cc01617 767 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 500 630 9.3E-46 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 DFR85_06690 6f2036dfabbba0ae5007c5c14cc01617 767 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 17 102 2.2E-33 T 31-10-2018 IPR003338 CDC48, N-terminal subdomain DFR85_06690 6f2036dfabbba0ae5007c5c14cc01617 767 TIGRFAM TIGR01243 CDC48: AAA family ATPase, CDC48 subfamily 17 751 0.0 T 31-10-2018 IPR005938 AAA ATPase, CDC48 family GO:0016787 Reactome: R-HSA-110320|Reactome: R-HSA-3371511|Reactome: R-HSA-382556|Reactome: R-HSA-532668|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5678895|Reactome: R-HSA-5689877|Reactome: R-HSA-5689896|Reactome: R-HSA-6798695|Reactome: R-HSA-8866654|Reactome: R-HSA-8876725 DFR85_06690 6f2036dfabbba0ae5007c5c14cc01617 767 SMART SM01072 118 181 5.2E-16 T 31-10-2018 IPR004201 CDC48, domain 2 DFR85_06690 6f2036dfabbba0ae5007c5c14cc01617 767 SUPERFAMILY SSF50692 12 100 1.17E-26 T 31-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily DFR85_06690 6f2036dfabbba0ae5007c5c14cc01617 767 Gene3D G3DSA:3.10.330.10 103 179 1.0E-6 T 31-10-2018 DFR85_06690 6f2036dfabbba0ae5007c5c14cc01617 767 Gene3D G3DSA:2.40.40.20 10 102 7.8E-33 T 31-10-2018 DFR85_06690 6f2036dfabbba0ae5007c5c14cc01617 767 ProSitePatterns PS00674 AAA-protein family signature. 327 345 - T 31-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 DFR85_06690 6f2036dfabbba0ae5007c5c14cc01617 767 SMART SM01073 16 102 4.1E-37 T 31-10-2018 IPR003338 CDC48, N-terminal subdomain DFR85_06690 6f2036dfabbba0ae5007c5c14cc01617 767 SUPERFAMILY SSF52540 458 750 1.13E-72 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_06690 6f2036dfabbba0ae5007c5c14cc01617 767 Gene3D G3DSA:3.40.50.300 180 357 6.8E-71 T 31-10-2018 DFR85_06690 6f2036dfabbba0ae5007c5c14cc01617 767 SMART SM00382 223 359 1.3E-23 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_06690 6f2036dfabbba0ae5007c5c14cc01617 767 SMART SM00382 496 633 7.8E-22 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_06690 6f2036dfabbba0ae5007c5c14cc01617 767 Gene3D G3DSA:1.10.8.60 632 733 5.6E-101 T 31-10-2018 DFR85_06690 6f2036dfabbba0ae5007c5c14cc01617 767 SUPERFAMILY SSF52540 184 450 1.9E-74 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_06690 6f2036dfabbba0ae5007c5c14cc01617 767 ProSitePatterns PS00674 AAA-protein family signature. 601 619 - T 31-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 DFR85_06690 6f2036dfabbba0ae5007c5c14cc01617 767 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 119 180 4.1E-15 T 31-10-2018 IPR004201 CDC48, domain 2 DFR85_06690 6f2036dfabbba0ae5007c5c14cc01617 767 Gene3D G3DSA:3.40.50.300 458 748 5.6E-101 T 31-10-2018 DFR85_06690 6f2036dfabbba0ae5007c5c14cc01617 767 SUPERFAMILY SSF54585 102 192 6.21E-19 T 31-10-2018 IPR029067 CDC48 domain 2-like superfamily DFR85_04685 867ab9b219e23017c4193dc144910ae2 398 Pfam PF01385 Probable transposase 178 284 6.8E-20 T 31-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 DFR85_04685 867ab9b219e23017c4193dc144910ae2 398 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 252 327 2.9E-15 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR85_04685 867ab9b219e23017c4193dc144910ae2 398 Pfam PF07282 Putative transposase DNA-binding domain 302 369 1.3E-23 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR85_09230 0ed98108eb4bf58f98d01e438d373aee 366 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 297 308 2.7E-26 T 31-10-2018 DFR85_09230 0ed98108eb4bf58f98d01e438d373aee 366 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 272 289 2.7E-26 T 31-10-2018 DFR85_09230 0ed98108eb4bf58f98d01e438d373aee 366 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 255 271 2.7E-26 T 31-10-2018 DFR85_09230 0ed98108eb4bf58f98d01e438d373aee 366 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 185 199 2.7E-26 T 31-10-2018 DFR85_09230 0ed98108eb4bf58f98d01e438d373aee 366 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 224 238 2.7E-26 T 31-10-2018 DFR85_09230 0ed98108eb4bf58f98d01e438d373aee 366 Gene3D G3DSA:3.40.50.880 160 366 6.1E-53 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like DFR85_09230 0ed98108eb4bf58f98d01e438d373aee 366 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 9 144 7.0E-48 T 31-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 DFR85_09230 0ed98108eb4bf58f98d01e438d373aee 366 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 10 365 3.5E-117 T 31-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 DFR85_09230 0ed98108eb4bf58f98d01e438d373aee 366 Pfam PF00117 Glutamine amidotransferase class-I 187 363 3.5E-40 T 31-10-2018 IPR017926 Glutamine amidotransferase DFR85_09230 0ed98108eb4bf58f98d01e438d373aee 366 SUPERFAMILY SSF52021 8 152 6.93E-49 T 31-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 DFR85_09230 0ed98108eb4bf58f98d01e438d373aee 366 SUPERFAMILY SSF52317 157 365 2.39E-52 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like DFR85_09230 0ed98108eb4bf58f98d01e438d373aee 366 Gene3D G3DSA:3.50.30.20 8 159 7.5E-54 T 31-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 DFR85_09230 0ed98108eb4bf58f98d01e438d373aee 366 PRINTS PR00096 Glutamine amidotransferase superfamily signature 255 266 4.2E-10 T 31-10-2018 DFR85_09230 0ed98108eb4bf58f98d01e438d373aee 366 PRINTS PR00096 Glutamine amidotransferase superfamily signature 340 353 4.2E-10 T 31-10-2018 DFR85_09230 0ed98108eb4bf58f98d01e438d373aee 366 PRINTS PR00096 Glutamine amidotransferase superfamily signature 227 236 4.2E-10 T 31-10-2018 DFR85_09230 0ed98108eb4bf58f98d01e438d373aee 366 PRINTS PR00097 Anthranilate synthase component II signature 227 236 5.7E-6 T 31-10-2018 DFR85_09230 0ed98108eb4bf58f98d01e438d373aee 366 PRINTS PR00097 Anthranilate synthase component II signature 340 353 5.7E-6 T 31-10-2018 DFR85_09230 0ed98108eb4bf58f98d01e438d373aee 366 PRINTS PR00097 Anthranilate synthase component II signature 255 266 5.7E-6 T 31-10-2018 DFR85_09230 0ed98108eb4bf58f98d01e438d373aee 366 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 8 365 40.288 T 31-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 DFR85_09230 0ed98108eb4bf58f98d01e438d373aee 366 SMART SM01097 8 145 2.8E-77 T 31-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 DFR85_02225 1d64f776e92b0f69c8f5407ab9b80a40 111 Gene3D G3DSA:1.10.10.10 11 107 1.7E-21 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_02225 1d64f776e92b0f69c8f5407ab9b80a40 111 SUPERFAMILY SSF46785 19 107 8.47E-16 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_02225 1d64f776e92b0f69c8f5407ab9b80a40 111 Pfam PF13601 Winged helix DNA-binding domain 26 104 2.3E-15 T 31-10-2018 IPR027395 Winged helix DNA-binding domain DFR85_14595 8423807f34e0316fabc779836359fb3b 393 Gene3D G3DSA:3.20.20.120 112 357 9.6E-111 T 31-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily DFR85_14595 8423807f34e0316fabc779836359fb3b 393 SUPERFAMILY SSF54826 1 123 9.96E-25 T 31-10-2018 DFR85_14595 8423807f34e0316fabc779836359fb3b 393 Pfam PF13378 Enolase C-terminal domain-like 143 364 1.0E-55 T 31-10-2018 IPR029065 Enolase C-terminal domain-like DFR85_14595 8423807f34e0316fabc779836359fb3b 393 SMART SM00922 139 244 9.0E-17 T 31-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal DFR85_14595 8423807f34e0316fabc779836359fb3b 393 Gene3D G3DSA:3.30.390.10 6 366 9.6E-111 T 31-10-2018 IPR029017 Enolase-like, N-terminal DFR85_14595 8423807f34e0316fabc779836359fb3b 393 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 23 118 3.2E-13 T 31-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain DFR85_14595 8423807f34e0316fabc779836359fb3b 393 SUPERFAMILY SSF51604 106 369 5.63E-74 T 31-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily DFR85_02665 a18264178d881a1db29b44d5103ff4b8 657 PIRSF PIRSF002741 50 651 9.4E-33 T 31-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 DFR85_02665 a18264178d881a1db29b44d5103ff4b8 657 Gene3D G3DSA:3.10.105.10 382 619 1.6E-21 T 31-10-2018 DFR85_02665 a18264178d881a1db29b44d5103ff4b8 657 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 100 567 1.9E-68 T 31-10-2018 IPR000914 Solute-binding protein family 5 domain DFR85_02665 a18264178d881a1db29b44d5103ff4b8 657 SUPERFAMILY SSF53850 60 648 1.99E-67 T 31-10-2018 DFR85_10405 24df87c63b71c8e9cd8cce422d9fc47a 479 SUPERFAMILY SSF101960 43 473 7.59E-124 T 31-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily DFR85_10405 24df87c63b71c8e9cd8cce422d9fc47a 479 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 32 468 1.2E-190 T 31-10-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 DFR85_10405 24df87c63b71c8e9cd8cce422d9fc47a 479 Pfam PF01458 Uncharacterized protein family (UPF0051) 222 448 2.7E-65 T 31-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 DFR85_07045 081897a2c9a9d7238d94921ec4cc9206 241 SUPERFAMILY SSF55174 52 94 3.27E-6 T 31-10-2018 DFR85_07045 081897a2c9a9d7238d94921ec4cc9206 241 Gene3D G3DSA:2.30.30.30 176 241 1.6E-12 T 31-10-2018 IPR014722 Ribosomal protein L2, domain 2 DFR85_07045 081897a2c9a9d7238d94921ec4cc9206 241 Hamap MF_00485 30S ribosomal protein S4e [rps4e]. 2 240 36.716 T 31-10-2018 IPR000876 Ribosomal protein S4e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07045 081897a2c9a9d7238d94921ec4cc9206 241 ProDom PD002667 RIBOSOMAL RIBONUCLEOPROTEIN RNA-BINDING 40S S4 S4 S4E 30S ISOFORM X 82 170 8.0E-24 T 31-10-2018 IPR013845 Ribosomal protein S4e, central region Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07045 081897a2c9a9d7238d94921ec4cc9206 241 Pfam PF08071 RS4NT (NUC023) domain 3 33 1.2E-4 T 31-10-2018 IPR013843 Ribosomal protein S4e, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07045 081897a2c9a9d7238d94921ec4cc9206 241 Pfam PF00900 Ribosomal family S4e 92 169 8.6E-18 T 31-10-2018 IPR013845 Ribosomal protein S4e, central region Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07045 081897a2c9a9d7238d94921ec4cc9206 241 SMART SM00363 37 102 1.7E-4 T 31-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07045 081897a2c9a9d7238d94921ec4cc9206 241 PIRSF PIRSF002116 1 241 5.5E-78 T 31-10-2018 IPR000876 Ribosomal protein S4e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07045 081897a2c9a9d7238d94921ec4cc9206 241 Gene3D G3DSA:2.40.50.740 119 172 9.0E-15 T 31-10-2018 IPR038237 Ribosomal protein S4e, central domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07045 081897a2c9a9d7238d94921ec4cc9206 241 Gene3D G3DSA:3.10.290.40 1 118 7.5E-33 T 31-10-2018 DFR85_07045 081897a2c9a9d7238d94921ec4cc9206 241 Pfam PF01479 S4 domain 49 85 1.7E-8 T 31-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_02800 fc421a721a45b384f325f85008927a33 453 Gene3D G3DSA:3.40.640.10 78 344 2.0E-133 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR85_02800 fc421a721a45b384f325f85008927a33 453 Pfam PF00202 Aminotransferase class-III 38 445 3.5E-101 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DFR85_02800 fc421a721a45b384f325f85008927a33 453 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 262 299 - T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DFR85_02800 fc421a721a45b384f325f85008927a33 453 Gene3D G3DSA:3.90.1150.10 34 442 2.0E-133 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 DFR85_02800 fc421a721a45b384f325f85008927a33 453 PIRSF PIRSF000521 143 450 8.1E-38 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DFR85_02800 fc421a721a45b384f325f85008927a33 453 PIRSF PIRSF000521 4 149 8.1E-9 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DFR85_02800 fc421a721a45b384f325f85008927a33 453 SUPERFAMILY SSF53383 34 449 9.18E-116 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase DFR85_09020 c9cdaa5a15cd94fa3a8347bf73ffdb36 165 Gene3D G3DSA:3.40.630.30 1 147 8.2E-10 T 31-10-2018 DFR85_09020 c9cdaa5a15cd94fa3a8347bf73ffdb36 165 SUPERFAMILY SSF55729 17 141 5.3E-11 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase DFR85_00820 993b5783902e9a6bf2a2aa18b139b7b1 139 Gene3D G3DSA:3.10.180.10 2 138 1.5E-38 T 31-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DFR85_00820 993b5783902e9a6bf2a2aa18b139b7b1 139 SUPERFAMILY SSF54593 5 139 4.43E-32 T 31-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DFR85_00820 993b5783902e9a6bf2a2aa18b139b7b1 139 ProSitePatterns PS00934 Glyoxalase I signature 1. 8 29 - T 31-10-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 DFR85_00820 993b5783902e9a6bf2a2aa18b139b7b1 139 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 122 3.2E-22 T 31-10-2018 DFR85_00820 993b5783902e9a6bf2a2aa18b139b7b1 139 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 6 137 8.4E-42 T 31-10-2018 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854|Reactome: R-HSA-71032 DFR85_08475 3a1d0c9929b2fadad9fd47017b0016d6 421 SUPERFAMILY SSF53223 10 188 3.2E-63 T 31-10-2018 DFR85_08475 3a1d0c9929b2fadad9fd47017b0016d6 421 SUPERFAMILY SSF51735 186 420 8.86E-69 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_08475 3a1d0c9929b2fadad9fd47017b0016d6 421 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 105 118 - T 31-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 DFR85_08475 3a1d0c9929b2fadad9fd47017b0016d6 421 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 97 111 1.0E-28 T 31-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 DFR85_08475 3a1d0c9929b2fadad9fd47017b0016d6 421 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 346 357 1.0E-28 T 31-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 DFR85_08475 3a1d0c9929b2fadad9fd47017b0016d6 421 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 219 239 1.0E-28 T 31-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 DFR85_08475 3a1d0c9929b2fadad9fd47017b0016d6 421 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 177 199 1.0E-28 T 31-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 DFR85_08475 3a1d0c9929b2fadad9fd47017b0016d6 421 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 40 167 2.3E-54 T 31-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 DFR85_08475 3a1d0c9929b2fadad9fd47017b0016d6 421 Gene3D G3DSA:3.40.50.720 186 421 1.7E-79 T 31-10-2018 DFR85_08475 3a1d0c9929b2fadad9fd47017b0016d6 421 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 186 419 1.5E-70 T 31-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 DFR85_08475 3a1d0c9929b2fadad9fd47017b0016d6 421 SMART SM00839 188 419 6.3E-82 T 31-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 DFR85_08475 3a1d0c9929b2fadad9fd47017b0016d6 421 Gene3D G3DSA:3.40.50.10860 42 185 8.4E-58 T 31-10-2018 DFR85_08475 3a1d0c9929b2fadad9fd47017b0016d6 421 PIRSF PIRSF000185 7 421 8.2E-157 T 31-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 DFR85_11435 7d171fb0fe568b1c1ca0a02312595b22 365 PRINTS PR00419 Adrenodoxin reductase family signature 5 27 4.7E-6 T 31-10-2018 DFR85_11435 7d171fb0fe568b1c1ca0a02312595b22 365 PRINTS PR00419 Adrenodoxin reductase family signature 28 41 4.7E-6 T 31-10-2018 DFR85_11435 7d171fb0fe568b1c1ca0a02312595b22 365 SUPERFAMILY SSF51905 5 345 5.83E-23 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_11435 7d171fb0fe568b1c1ca0a02312595b22 365 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 334 4.6E-17 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR85_11435 7d171fb0fe568b1c1ca0a02312595b22 365 Gene3D G3DSA:3.50.50.60 2 152 3.0E-15 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_11435 7d171fb0fe568b1c1ca0a02312595b22 365 Gene3D G3DSA:3.50.50.60 204 347 3.9E-6 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_01690 8f19093b443c9f6c7ab187a52a8feb9a 931 Hamap MF_00049_A Leucine--tRNA ligase [leuS]. 7 931 15.294 T 31-10-2018 IPR020791 Leucine-tRNA ligase, archaeal GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4 DFR85_01690 8f19093b443c9f6c7ab187a52a8feb9a 931 Gene3D G3DSA:3.90.740.10 199 432 8.2E-231 T 31-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 DFR85_01690 8f19093b443c9f6c7ab187a52a8feb9a 931 SUPERFAMILY SSF52374 9 662 2.62E-84 T 31-10-2018 DFR85_01690 8f19093b443c9f6c7ab187a52a8feb9a 931 TIGRFAM TIGR00395 leuS_arch: leucine--tRNA ligase 9 930 5.3E-238 T 31-10-2018 IPR004493 Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 DFR85_01690 8f19093b443c9f6c7ab187a52a8feb9a 931 Gene3D G3DSA:3.40.50.620 9 659 8.2E-231 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR85_01690 8f19093b443c9f6c7ab187a52a8feb9a 931 SUPERFAMILY SSF50677 208 424 6.59E-31 T 31-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 DFR85_01690 8f19093b443c9f6c7ab187a52a8feb9a 931 Gene3D G3DSA:1.10.730.10 664 773 1.4E-15 T 31-10-2018 DFR85_01690 8f19093b443c9f6c7ab187a52a8feb9a 931 SUPERFAMILY SSF47323 675 846 1.12E-20 T 31-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR85_01690 8f19093b443c9f6c7ab187a52a8feb9a 931 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 12 660 8.2E-58 T 31-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR85_01690 8f19093b443c9f6c7ab187a52a8feb9a 931 Pfam PF08264 Anticodon-binding domain of tRNA 695 820 2.2E-17 T 31-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 DFR85_06705 1ed2a625749fbacaa70b70350129b7c1 218 SUPERFAMILY SSF51735 4 114 6.08E-19 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_06705 1ed2a625749fbacaa70b70350129b7c1 218 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 7 210 1.6E-18 T 31-10-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 DFR85_06705 1ed2a625749fbacaa70b70350129b7c1 218 Pfam PF13241 Putative NAD(P)-binding 9 116 2.6E-19 T 31-10-2018 DFR85_06705 1ed2a625749fbacaa70b70350129b7c1 218 SUPERFAMILY SSF75615 116 197 3.14E-9 T 31-10-2018 DFR85_06705 1ed2a625749fbacaa70b70350129b7c1 218 Gene3D G3DSA:3.40.50.720 6 132 4.2E-27 T 31-10-2018 DFR85_07925 8fd63364c5d3437b11456a07ac9eb8ae 128 Gene3D G3DSA:3.40.50.1400 2 125 2.1E-27 T 31-10-2018 DFR85_07925 8fd63364c5d3437b11456a07ac9eb8ae 128 SUPERFAMILY SSF53800 1 121 6.02E-27 T 31-10-2018 DFR85_07925 8fd63364c5d3437b11456a07ac9eb8ae 128 Pfam PF01903 CbiX 9 117 2.2E-24 T 31-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 DFR85_07925 8fd63364c5d3437b11456a07ac9eb8ae 128 Hamap MF_00785 Sirohydrochlorin cobaltochelatase [cbiX]. 1 122 26.455 T 31-10-2018 IPR023652 Sirohydrochlorin cobaltochelatase GO:0016852|GO:0050897 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 DFR85_14835 05da213a672d693e989683a7c36ecfe3 367 SMART SM00729 7 230 0.003 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 DFR85_14835 05da213a672d693e989683a7c36ecfe3 367 Gene3D G3DSA:3.20.20.70 3 311 4.6E-30 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_14835 05da213a672d693e989683a7c36ecfe3 367 PIRSF PIRSF037420 2 362 3.3E-43 T 31-10-2018 IPR017200 Coenzyme PQQ synthesis protein E DFR85_14835 05da213a672d693e989683a7c36ecfe3 367 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 267 351 1.4E-10 T 31-10-2018 IPR023885 4Fe4S-binding SPASM domain DFR85_14835 05da213a672d693e989683a7c36ecfe3 367 Pfam PF04055 Radical SAM superfamily 13 189 3.3E-10 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR85_14835 05da213a672d693e989683a7c36ecfe3 367 Pfam PF13186 Iron-sulfur cluster-binding domain 262 324 4.0E-8 T 31-10-2018 IPR023885 4Fe4S-binding SPASM domain DFR85_14835 05da213a672d693e989683a7c36ecfe3 367 SUPERFAMILY SSF102114 5 332 3.14E-46 T 31-10-2018 DFR85_03125 b5ce9153b990a7bd2abd256c0eed352e 764 SUPERFAMILY SSF48371 518 733 1.66E-25 T 31-10-2018 IPR016024 Armadillo-type fold DFR85_03125 b5ce9153b990a7bd2abd256c0eed352e 764 Pfam PF13646 HEAT repeats 517 598 5.1E-11 T 31-10-2018 DFR85_03125 b5ce9153b990a7bd2abd256c0eed352e 764 Pfam PF13646 HEAT repeats 682 754 5.3E-9 T 31-10-2018 DFR85_03125 b5ce9153b990a7bd2abd256c0eed352e 764 SUPERFAMILY SSF55486 214 445 7.87E-62 T 31-10-2018 DFR85_03125 b5ce9153b990a7bd2abd256c0eed352e 764 Pfam PF01433 Peptidase family M1 domain 224 434 1.3E-44 T 31-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DFR85_03125 b5ce9153b990a7bd2abd256c0eed352e 764 Gene3D G3DSA:1.25.10.10 503 656 1.0E-19 T 31-10-2018 IPR011989 Armadillo-like helical DFR85_03125 b5ce9153b990a7bd2abd256c0eed352e 764 Gene3D G3DSA:1.25.10.10 657 764 4.7E-13 T 31-10-2018 IPR011989 Armadillo-like helical DFR85_03125 b5ce9153b990a7bd2abd256c0eed352e 764 SUPERFAMILY SSF63737 32 199 1.26E-20 T 31-10-2018 DFR85_03125 b5ce9153b990a7bd2abd256c0eed352e 764 SMART SM00567 E-Z type HEAT repeats 716 744 1000.0 T 31-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 DFR85_03125 b5ce9153b990a7bd2abd256c0eed352e 764 SMART SM00567 E-Z type HEAT repeats 621 650 110.0 T 31-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 DFR85_03125 b5ce9153b990a7bd2abd256c0eed352e 764 SMART SM00567 E-Z type HEAT repeats 686 714 6.4 T 31-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 DFR85_03125 b5ce9153b990a7bd2abd256c0eed352e 764 SMART SM00567 E-Z type HEAT repeats 588 618 680.0 T 31-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 DFR85_03125 b5ce9153b990a7bd2abd256c0eed352e 764 SMART SM00567 E-Z type HEAT repeats 558 587 0.016 T 31-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 DFR85_03125 b5ce9153b990a7bd2abd256c0eed352e 764 SMART SM00567 E-Z type HEAT repeats 527 556 370.0 T 31-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 DFR85_03125 b5ce9153b990a7bd2abd256c0eed352e 764 Gene3D G3DSA:1.10.390.60 203 439 3.8E-59 T 31-10-2018 DFR85_03125 b5ce9153b990a7bd2abd256c0eed352e 764 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 136 151 3.0E-8 T 31-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DFR85_03125 b5ce9153b990a7bd2abd256c0eed352e 764 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 290 305 3.0E-8 T 31-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DFR85_03125 b5ce9153b990a7bd2abd256c0eed352e 764 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 309 321 3.0E-8 T 31-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DFR85_03125 b5ce9153b990a7bd2abd256c0eed352e 764 Gene3D G3DSA:2.60.40.1730 32 199 4.1E-19 T 31-10-2018 DFR85_00510 9f82683559629611820e31e8e7bd5205 257 Gene3D G3DSA:3.40.50.300 2 239 2.1E-21 T 31-10-2018 DFR85_00510 9f82683559629611820e31e8e7bd5205 257 Pfam PF13614 AAA domain 3 127 6.3E-12 T 31-10-2018 IPR025669 AAA domain DFR85_00510 9f82683559629611820e31e8e7bd5205 257 SUPERFAMILY SSF52540 1 227 3.62E-21 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_01420 fd70931e032dafc40d266f0ee2efd77f 162 SUPERFAMILY SSF88723 4 115 2.99E-6 T 31-10-2018 IPR029060 PIN-like domain superfamily DFR85_01420 fd70931e032dafc40d266f0ee2efd77f 162 Gene3D G3DSA:3.40.50.1010 1 123 2.5E-29 T 31-10-2018 DFR85_01420 fd70931e032dafc40d266f0ee2efd77f 162 SMART SM00670 2 103 6.8E-6 T 31-10-2018 IPR002716 PIN domain DFR85_01420 fd70931e032dafc40d266f0ee2efd77f 162 Pfam PF17146 PIN domain of ribonuclease 4 89 2.0E-17 T 31-10-2018 IPR033411 Ribonuclease, PIN domain Reactome: R-HSA-6791226 DFR85_02570 7844333b323fe10abba7d29f2506a1b5 266 SUPERFAMILY SSF52540 2 227 5.78E-59 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_02570 7844333b323fe10abba7d29f2506a1b5 266 Gene3D G3DSA:3.40.50.300 1 229 5.4E-59 T 31-10-2018 DFR85_02570 7844333b323fe10abba7d29f2506a1b5 266 SMART SM00382 26 204 7.1E-12 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_02570 7844333b323fe10abba7d29f2506a1b5 266 ProSitePatterns PS00211 ABC transporters family signature. 127 141 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DFR85_02570 7844333b323fe10abba7d29f2506a1b5 266 Pfam PF00005 ABC transporter 18 154 5.2E-28 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR85_13965 88c84a6a6c5dcd05597217e1cd36ef1c 972 SUPERFAMILY SSF53706 190 804 2.09E-198 T 31-10-2018 DFR85_13965 88c84a6a6c5dcd05597217e1cd36ef1c 972 Gene3D G3DSA:2.20.25.90 253 308 5.0E-17 T 31-10-2018 DFR85_13965 88c84a6a6c5dcd05597217e1cd36ef1c 972 SUPERFAMILY SSF54862 74 207 5.44E-33 T 31-10-2018 DFR85_13965 88c84a6a6c5dcd05597217e1cd36ef1c 972 SUPERFAMILY SSF50692 789 929 1.43E-39 T 31-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily DFR85_13965 88c84a6a6c5dcd05597217e1cd36ef1c 972 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 82 120 3.5E-10 T 31-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_13965 88c84a6a6c5dcd05597217e1cd36ef1c 972 SUPERFAMILY SSF54292 4 73 1.62E-16 T 31-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 DFR85_13965 88c84a6a6c5dcd05597217e1cd36ef1c 972 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 4 75 3.7E-15 T 31-10-2018 DFR85_13965 88c84a6a6c5dcd05597217e1cd36ef1c 972 PIRSF PIRSF036643 1 961 0.0 T 31-10-2018 DFR85_13965 88c84a6a6c5dcd05597217e1cd36ef1c 972 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 258 926 9.4E-275 T 31-10-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.17.1.9|KEGG: 00680+1.17.1.9|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696|MetaCyc: PWY-7985 DFR85_13965 88c84a6a6c5dcd05597217e1cd36ef1c 972 Gene3D G3DSA:3.40.228.10 387 586 8.6E-176 T 31-10-2018 DFR85_13965 88c84a6a6c5dcd05597217e1cd36ef1c 972 Gene3D G3DSA:3.40.50.740 314 775 8.6E-176 T 31-10-2018 DFR85_13965 88c84a6a6c5dcd05597217e1cd36ef1c 972 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 186 197 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR85_13965 88c84a6a6c5dcd05597217e1cd36ef1c 972 Gene3D G3DSA:3.30.70.20 124 204 5.0E-22 T 31-10-2018 DFR85_13965 88c84a6a6c5dcd05597217e1cd36ef1c 972 SMART SM00926 253 307 2.8E-17 T 31-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_13965 88c84a6a6c5dcd05597217e1cd36ef1c 972 Pfam PF12838 4Fe-4S dicluster domain 142 200 2.5E-8 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR85_13965 88c84a6a6c5dcd05597217e1cd36ef1c 972 Pfam PF01568 Molydopterin dinucleotide binding domain 816 923 3.3E-22 T 31-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 DFR85_13965 88c84a6a6c5dcd05597217e1cd36ef1c 972 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 253 307 8.6E-18 T 31-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_13965 88c84a6a6c5dcd05597217e1cd36ef1c 972 Gene3D G3DSA:3.10.20.740 3 122 1.5E-34 T 31-10-2018 DFR85_13965 88c84a6a6c5dcd05597217e1cd36ef1c 972 Gene3D G3DSA:2.40.40.20 808 929 8.1E-33 T 31-10-2018 DFR85_13965 88c84a6a6c5dcd05597217e1cd36ef1c 972 Pfam PF00384 Molybdopterin oxidoreductase 309 732 4.6E-90 T 31-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_13965 88c84a6a6c5dcd05597217e1cd36ef1c 972 SMART SM00929 82 122 3.6E-9 T 31-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_11470 cfb32345d7a5825850b7bc659357a678 176 SUPERFAMILY SSF102405 2 165 1.39E-22 T 31-10-2018 DFR85_11470 cfb32345d7a5825850b7bc659357a678 176 Gene3D G3DSA:3.40.50.450 26 167 2.5E-19 T 31-10-2018 DFR85_08170 362e9bd00f730bf7dc7bc740b6f78653 298 Hamap MF_02040 Iron-sulfur cluster carrier protein. 37 288 35.962 T 31-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein DFR85_08170 362e9bd00f730bf7dc7bc740b6f78653 298 Gene3D G3DSA:3.40.50.300 29 283 1.7E-86 T 31-10-2018 DFR85_08170 362e9bd00f730bf7dc7bc740b6f78653 298 SUPERFAMILY SSF52540 44 292 2.0E-55 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_08170 362e9bd00f730bf7dc7bc740b6f78653 298 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 41 287 4.1E-99 T 31-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 DFR85_08170 362e9bd00f730bf7dc7bc740b6f78653 298 ProSitePatterns PS01215 Mrp family signature. 150 166 - T 31-10-2018 IPR000808 Mrp, conserved site GO:0005524 DFR85_14695 a8e49730518b0166c9332d32e479e739 159 Pfam PF11485 Protein of unknown function (DUF3211) 5 159 1.1E-33 T 31-10-2018 IPR021578 Protein of unknown function DUF3211 DFR85_14695 a8e49730518b0166c9332d32e479e739 159 Gene3D G3DSA:3.30.530.20 1 159 1.6E-11 T 31-10-2018 IPR023393 START-like domain superfamily DFR85_08540 55fae5d6bbf78d46aa1bac5ac45e9264 378 PIRSF PIRSF016578 5 371 5.2E-17 T 31-10-2018 DFR85_08540 55fae5d6bbf78d46aa1bac5ac45e9264 378 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 105 6.2E-17 T 31-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 DFR85_08540 55fae5d6bbf78d46aa1bac5ac45e9264 378 SUPERFAMILY SSF56645 4 236 1.15E-54 T 31-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 DFR85_08540 55fae5d6bbf78d46aa1bac5ac45e9264 378 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 373 4.6E-42 T 31-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DFR85_08540 55fae5d6bbf78d46aa1bac5ac45e9264 378 Gene3D G3DSA:1.10.540.10 2 116 2.3E-19 T 31-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 DFR85_08540 55fae5d6bbf78d46aa1bac5ac45e9264 378 SUPERFAMILY SSF47203 224 374 8.38E-44 T 31-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 DFR85_08540 55fae5d6bbf78d46aa1bac5ac45e9264 378 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 121 133 - T 31-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 DFR85_08540 55fae5d6bbf78d46aa1bac5ac45e9264 378 Gene3D G3DSA:2.40.110.10 118 231 3.5E-33 T 31-10-2018 DFR85_08540 55fae5d6bbf78d46aa1bac5ac45e9264 378 Gene3D G3DSA:1.20.140.10 232 378 5.8E-42 T 31-10-2018 DFR85_08540 55fae5d6bbf78d46aa1bac5ac45e9264 378 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 119 214 3.2E-22 T 31-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 DFR85_08640 e7d2ed53dbd557bf035f51027b96f2ea 226 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 201 217 - T 31-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 DFR85_08640 e7d2ed53dbd557bf035f51027b96f2ea 226 SUPERFAMILY SSF48150 26 222 4.4E-57 T 31-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 DFR85_08640 e7d2ed53dbd557bf035f51027b96f2ea 226 Gene3D G3DSA:1.10.340.30 27 147 7.9E-57 T 31-10-2018 DFR85_08640 e7d2ed53dbd557bf035f51027b96f2ea 226 SMART SM00478 44 199 1.6E-39 T 31-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 DFR85_08640 e7d2ed53dbd557bf035f51027b96f2ea 226 PIRSF PIRSF001435 7 225 4.0E-57 T 31-10-2018 DFR85_08640 e7d2ed53dbd557bf035f51027b96f2ea 226 SMART SM00525 200 220 0.0035 T 31-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 DFR85_08640 e7d2ed53dbd557bf035f51027b96f2ea 226 Gene3D G3DSA:1.10.1670.10 24 217 7.9E-57 T 31-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 DFR85_08640 e7d2ed53dbd557bf035f51027b96f2ea 226 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 40 179 2.4E-16 T 31-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 DFR85_05445 d25069a644b7dc34475d1662a1640c67 285 SMART SM00729 11 213 2.3E-9 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 DFR85_05445 d25069a644b7dc34475d1662a1640c67 285 SUPERFAMILY SSF102114 11 244 1.07E-26 T 31-10-2018 DFR85_05445 d25069a644b7dc34475d1662a1640c67 285 Gene3D G3DSA:3.20.20.70 7 244 5.3E-20 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_05445 d25069a644b7dc34475d1662a1640c67 285 Pfam PF04055 Radical SAM superfamily 17 173 2.6E-12 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR85_14520 879df850803a6a50b229cbf5dcbe44cb 290 Gene3D G3DSA:1.10.1040.10 162 289 4.8E-37 T 31-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 DFR85_14520 879df850803a6a50b229cbf5dcbe44cb 290 SUPERFAMILY SSF48179 162 286 1.7E-34 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 DFR85_14520 879df850803a6a50b229cbf5dcbe44cb 290 SUPERFAMILY SSF51735 1 162 1.02E-52 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_14520 879df850803a6a50b229cbf5dcbe44cb 290 Gene3D G3DSA:3.40.50.720 1 161 6.9E-59 T 31-10-2018 DFR85_14520 879df850803a6a50b229cbf5dcbe44cb 290 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 5 18 - T 31-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 DFR85_14520 879df850803a6a50b229cbf5dcbe44cb 290 PIRSF PIRSF000103 1 290 1.4E-88 T 31-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 DFR85_14520 879df850803a6a50b229cbf5dcbe44cb 290 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 164 284 8.5E-31 T 31-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 DFR85_14520 879df850803a6a50b229cbf5dcbe44cb 290 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 161 2.2E-54 T 31-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 DFR85_03020 f17e7b29c5a74e52093a87a8d5a7e7fe 391 Gene3D G3DSA:3.20.20.80 1 390 3.8E-92 T 31-10-2018 DFR85_03020 f17e7b29c5a74e52093a87a8d5a7e7fe 391 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 313 321 - T 31-10-2018 IPR018120 Glycoside hydrolase family 1, active site DFR85_03020 f17e7b29c5a74e52093a87a8d5a7e7fe 391 SUPERFAMILY SSF51445 2 387 6.95E-85 T 31-10-2018 IPR017853 Glycoside hydrolase superfamily DFR85_03020 f17e7b29c5a74e52093a87a8d5a7e7fe 391 PRINTS PR00131 Glycosyl hydrolase family 1 signature 313 321 1.6E-13 T 31-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 DFR85_03020 f17e7b29c5a74e52093a87a8d5a7e7fe 391 PRINTS PR00131 Glycosyl hydrolase family 1 signature 367 379 1.6E-13 T 31-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 DFR85_03020 f17e7b29c5a74e52093a87a8d5a7e7fe 391 PRINTS PR00131 Glycosyl hydrolase family 1 signature 343 360 1.6E-13 T 31-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 DFR85_03020 f17e7b29c5a74e52093a87a8d5a7e7fe 391 PRINTS PR00131 Glycosyl hydrolase family 1 signature 247 261 1.6E-13 T 31-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 DFR85_03020 f17e7b29c5a74e52093a87a8d5a7e7fe 391 Pfam PF00232 Glycosyl hydrolase family 1 243 387 1.4E-22 T 31-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 DFR85_03020 f17e7b29c5a74e52093a87a8d5a7e7fe 391 Pfam PF00232 Glycosyl hydrolase family 1 2 225 2.2E-27 T 31-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 DFR85_02305 cae28c7bde60dd94c0a104586acfd304 315 SUPERFAMILY SSF52540 1 247 5.03E-61 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_02305 cae28c7bde60dd94c0a104586acfd304 315 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 227 291 3.3E-16 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 DFR85_02305 cae28c7bde60dd94c0a104586acfd304 315 Gene3D G3DSA:3.40.50.300 1 315 1.7E-84 T 31-10-2018 DFR85_02305 cae28c7bde60dd94c0a104586acfd304 315 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DFR85_02305 cae28c7bde60dd94c0a104586acfd304 315 SMART SM00382 30 242 4.7E-9 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_02305 cae28c7bde60dd94c0a104586acfd304 315 Pfam PF00005 ABC transporter 22 175 6.2E-31 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR85_02305 cae28c7bde60dd94c0a104586acfd304 315 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 227 311 5.5E-21 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 DFR85_13410 a52340a9b4b040b92f45d32ee041ff3b 215 Gene3D G3DSA:2.40.50.580 5 75 1.3E-10 T 31-10-2018 DFR85_13410 a52340a9b4b040b92f45d32ee041ff3b 215 Hamap MF_00095 Sugar fermentation stimulation protein A [sfsA]. 4 212 41.145 T 31-10-2018 IPR005224 Sugar fermentation stimulation protein DFR85_13410 a52340a9b4b040b92f45d32ee041ff3b 215 Gene3D G3DSA:3.40.1350.60 76 211 6.0E-39 T 31-10-2018 DFR85_13410 a52340a9b4b040b92f45d32ee041ff3b 215 Pfam PF03749 Sugar fermentation stimulation protein 16 196 4.2E-55 T 31-10-2018 IPR005224 Sugar fermentation stimulation protein DFR85_13410 a52340a9b4b040b92f45d32ee041ff3b 215 TIGRFAM TIGR00230 sfsA: sugar fermentation stimulation protein 2 202 6.3E-46 T 31-10-2018 IPR005224 Sugar fermentation stimulation protein DFR85_03895 b45d68dfad0abac47922076a7d99bc0d 246 ProSitePatterns PS00211 ABC transporters family signature. 107 121 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DFR85_03895 b45d68dfad0abac47922076a7d99bc0d 246 SMART SM00382 6 189 3.5E-12 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_03895 b45d68dfad0abac47922076a7d99bc0d 246 Pfam PF00005 ABC transporter 3 134 9.9E-25 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR85_03895 b45d68dfad0abac47922076a7d99bc0d 246 Gene3D G3DSA:3.40.50.300 1 223 2.0E-51 T 31-10-2018 DFR85_03895 b45d68dfad0abac47922076a7d99bc0d 246 SUPERFAMILY SSF52540 2 181 8.73E-50 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_01140 730cd78df322859ac24a52981898f236 479 Gene3D G3DSA:1.20.140.10 272 477 6.1E-60 T 31-10-2018 DFR85_01140 730cd78df322859ac24a52981898f236 479 SUPERFAMILY SSF56645 1 268 1.69E-65 T 31-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 DFR85_01140 730cd78df322859ac24a52981898f236 479 Gene3D G3DSA:2.40.110.10 140 269 3.1E-46 T 31-10-2018 DFR85_01140 730cd78df322859ac24a52981898f236 479 Gene3D G3DSA:1.10.3140.10 1 139 6.9E-26 T 31-10-2018 DFR85_01140 730cd78df322859ac24a52981898f236 479 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 5 268 3.6E-86 T 31-10-2018 IPR024674 HpaB/PvcC/4-BUDH N-terminal DFR85_01140 730cd78df322859ac24a52981898f236 479 PIRSF PIRSF000331 1 479 6.0E-142 T 31-10-2018 IPR004925 HpaB/PvcC/4-BUDH DFR85_01140 730cd78df322859ac24a52981898f236 479 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 275 475 5.1E-54 T 31-10-2018 IPR024719 HpaB/PvcC/4-BUDH C-terminal DFR85_01140 730cd78df322859ac24a52981898f236 479 SUPERFAMILY SSF47203 259 475 1.26E-56 T 31-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 DFR85_15835 6a846cebd9bffad09fdc2a9e3eac4841 424 Pfam PF03972 MmgE/PrpD family 5 400 2.4E-97 T 31-10-2018 IPR005656 MmgE/PrpD GO:0016829 DFR85_15835 6a846cebd9bffad09fdc2a9e3eac4841 424 Gene3D G3DSA:3.30.1330.120 255 381 5.0E-93 T 31-10-2018 DFR85_15835 6a846cebd9bffad09fdc2a9e3eac4841 424 SUPERFAMILY SSF103378 1 418 4.58E-98 T 31-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 DFR85_15835 6a846cebd9bffad09fdc2a9e3eac4841 424 Gene3D G3DSA:1.10.4100.10 14 409 5.0E-93 T 31-10-2018 DFR85_02890 59a3c405f8783cbe24f8ed79f9c8d29b 408 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 234 318 7.8E-24 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR85_02890 59a3c405f8783cbe24f8ed79f9c8d29b 408 Pfam PF07282 Putative transposase DNA-binding domain 291 363 4.0E-15 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR85_03285 60763821d4a6ea63337ad5d8ae55369b 103 Gene3D G3DSA:3.30.2310.20 5 102 6.4E-7 T 31-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily DFR85_03285 60763821d4a6ea63337ad5d8ae55369b 103 SUPERFAMILY SSF143011 11 98 3.14E-9 T 31-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily DFR85_05890 babdd603b16af73d25bc339b33f72b9b 509 Gene3D G3DSA:3.30.470.130 1 455 3.5E-169 T 31-10-2018 DFR85_05890 babdd603b16af73d25bc339b33f72b9b 509 SUPERFAMILY SSF52440 2 114 4.53E-48 T 31-10-2018 IPR016185 Pre-ATP-grasp domain superfamily DFR85_05890 babdd603b16af73d25bc339b33f72b9b 509 SMART SM00878 341 447 9.0E-53 T 31-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 DFR85_05890 babdd603b16af73d25bc339b33f72b9b 509 SUPERFAMILY SSF56059 85 332 7.78E-57 T 31-10-2018 DFR85_05890 babdd603b16af73d25bc339b33f72b9b 509 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 117 325 3.2E-62 T 31-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 DFR85_05890 babdd603b16af73d25bc339b33f72b9b 509 SUPERFAMILY SSF51246 336 453 1.78E-38 T 31-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 DFR85_05890 babdd603b16af73d25bc339b33f72b9b 509 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 155 169 - T 31-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 DFR85_05890 babdd603b16af73d25bc339b33f72b9b 509 Pfam PF02785 Biotin carboxylase C-terminal domain 341 447 4.8E-36 T 31-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 DFR85_05890 babdd603b16af73d25bc339b33f72b9b 509 Pfam PF00289 Biotin carboxylase, N-terminal domain 4 112 1.4E-44 T 31-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 DFR85_07615 9148e15bef75038ea497bcf57bc3f16b 324 SUPERFAMILY SSF47794 6 70 1.73E-10 T 31-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 DFR85_07615 9148e15bef75038ea497bcf57bc3f16b 324 SUPERFAMILY SSF52540 86 321 1.33E-53 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_07615 9148e15bef75038ea497bcf57bc3f16b 324 Hamap MF_00348 DNA repair and recombination protein RadA [radA]. 11 321 68.139 T 31-10-2018 IPR011938 DNA recombination/repair protein RadA GO:0003684|GO:0005524|GO:0006281|GO:0006310|GO:0008094 DFR85_07615 9148e15bef75038ea497bcf57bc3f16b 324 TIGRFAM TIGR02236 recomb_radA: DNA repair and recombination protein RadA 14 321 1.3E-139 T 31-10-2018 IPR011938 DNA recombination/repair protein RadA GO:0003684|GO:0005524|GO:0006281|GO:0006310|GO:0008094 DFR85_07615 9148e15bef75038ea497bcf57bc3f16b 324 PIRSF PIRSF005856 4 324 2.3E-123 T 31-10-2018 IPR016467 DNA recombination and repair protein, RecA-like Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 DFR85_07615 9148e15bef75038ea497bcf57bc3f16b 324 Pfam PF08423 Rad51 73 322 1.8E-86 T 31-10-2018 IPR013632 DNA recombination and repair protein Rad51-like, C-terminal Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 DFR85_07615 9148e15bef75038ea497bcf57bc3f16b 324 Gene3D G3DSA:1.10.150.20 21 84 3.4E-21 T 31-10-2018 DFR85_07615 9148e15bef75038ea497bcf57bc3f16b 324 SMART SM00382 106 291 8.0E-8 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_07615 9148e15bef75038ea497bcf57bc3f16b 324 Pfam PF14520 Helix-hairpin-helix domain 16 67 2.8E-9 T 31-10-2018 DFR85_07615 9148e15bef75038ea497bcf57bc3f16b 324 Gene3D G3DSA:3.40.50.300 85 324 6.6E-76 T 31-10-2018 DFR85_02315 4973429cfa73f8e924f5689d89cdd678 139 Pfam PF13279 Thioesterase-like superfamily 11 131 6.3E-8 T 31-10-2018 DFR85_02315 4973429cfa73f8e924f5689d89cdd678 139 SUPERFAMILY SSF54637 4 132 8.8E-31 T 31-10-2018 IPR029069 HotDog domain superfamily DFR85_02315 4973429cfa73f8e924f5689d89cdd678 139 PIRSF PIRSF003230 4 137 3.6E-21 T 31-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 DFR85_02315 4973429cfa73f8e924f5689d89cdd678 139 Gene3D G3DSA:3.10.129.10 2 133 2.3E-30 T 31-10-2018 DFR85_12985 e25efa854e80857fd0bc0ec520fe52eb 421 Gene3D G3DSA:1.20.1250.20 12 417 3.9E-37 T 31-10-2018 DFR85_12985 e25efa854e80857fd0bc0ec520fe52eb 421 Pfam PF07690 Major Facilitator Superfamily 28 367 1.4E-17 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_12985 e25efa854e80857fd0bc0ec520fe52eb 421 SUPERFAMILY SSF103473 5 416 9.68E-41 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_07445 dc1852717f935f0efb694b335243920e 73 Hamap MF_00511 30S ribosomal protein S17e [rps17e]. 1 63 18.336 T 31-10-2018 IPR001210 Ribosomal protein S17e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07445 dc1852717f935f0efb694b335243920e 73 Gene3D G3DSA:1.10.60.20 1 62 1.5E-23 T 31-10-2018 IPR036401 Ribosomal protein S17e-like superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07445 dc1852717f935f0efb694b335243920e 73 SUPERFAMILY SSF116820 1 60 3.79E-20 T 31-10-2018 IPR036401 Ribosomal protein S17e-like superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07445 dc1852717f935f0efb694b335243920e 73 ProSitePatterns PS00712 Ribosomal protein S17e signature. 41 56 - T 31-10-2018 IPR018273 Ribosomal protein S17e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07445 dc1852717f935f0efb694b335243920e 73 Pfam PF00833 Ribosomal S17 1 62 2.4E-13 T 31-10-2018 IPR001210 Ribosomal protein S17e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_14940 81e0b5f202e2be2190eb1908b5992867 664 Pfam PF13193 AMP-binding enzyme C-terminal domain 542 620 3.4E-27 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain DFR85_14940 81e0b5f202e2be2190eb1908b5992867 664 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 28 80 5.9E-19 T 31-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 DFR85_14940 81e0b5f202e2be2190eb1908b5992867 664 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 24 652 1.7E-283 T 31-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 DFR85_14940 81e0b5f202e2be2190eb1908b5992867 664 Pfam PF00501 AMP-binding enzyme 92 534 3.4E-90 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 DFR85_14940 81e0b5f202e2be2190eb1908b5992867 664 SUPERFAMILY SSF56801 16 651 1.44E-171 T 31-10-2018 DFR85_14940 81e0b5f202e2be2190eb1908b5992867 664 ProSitePatterns PS00455 Putative AMP-binding domain signature. 270 281 - T 31-10-2018 IPR020845 AMP-binding, conserved site DFR85_14940 81e0b5f202e2be2190eb1908b5992867 664 Gene3D G3DSA:3.40.50.12780 54 527 2.5E-97 T 31-10-2018 DFR85_14940 81e0b5f202e2be2190eb1908b5992867 664 Gene3D G3DSA:3.30.300.30 529 660 3.4E-28 T 31-10-2018 DFR85_12140 f6b51ffbcf3b2499631d074ad043469f 305 Gene3D G3DSA:3.100.10.20 2 76 2.3E-15 T 31-10-2018 DFR85_12140 f6b51ffbcf3b2499631d074ad043469f 305 Gene3D G3DSA:1.20.120.920 82 305 1.7E-49 T 31-10-2018 DFR85_12140 f6b51ffbcf3b2499631d074ad043469f 305 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 4 299 5.6E-63 T 31-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 DFR85_12140 f6b51ffbcf3b2499631d074ad043469f 305 Pfam PF01867 CRISPR associated protein Cas1 6 258 4.5E-48 T 31-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 DFR85_12140 f6b51ffbcf3b2499631d074ad043469f 305 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 2 290 20.698 T 31-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 DFR85_01945 1bd6fc069ef8baeb32b128d576e47a9b 178 Gene3D G3DSA:3.40.980.10 1 177 3.2E-42 T 31-10-2018 IPR036425 MoaB/Mog-like domain superfamily DFR85_01945 1bd6fc069ef8baeb32b128d576e47a9b 178 PIRSF PIRSF006443 1 178 4.5E-57 T 31-10-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 DFR85_01945 1bd6fc069ef8baeb32b128d576e47a9b 178 SUPERFAMILY SSF53218 12 175 1.83E-37 T 31-10-2018 IPR036425 MoaB/Mog-like domain superfamily DFR85_01945 1bd6fc069ef8baeb32b128d576e47a9b 178 Pfam PF00994 Probable molybdopterin binding domain 19 170 2.1E-32 T 31-10-2018 IPR001453 MoaB/Mog domain DFR85_01945 1bd6fc069ef8baeb32b128d576e47a9b 178 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 17 166 1.5E-30 T 31-10-2018 IPR001453 MoaB/Mog domain DFR85_01945 1bd6fc069ef8baeb32b128d576e47a9b 178 SMART SM00852 18 171 4.1E-22 T 31-10-2018 IPR001453 MoaB/Mog domain DFR85_04365 624ee9cdece49058ba1087193afdad96 368 Pfam PF00534 Glycosyl transferases group 1 184 347 1.2E-21 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 DFR85_04365 624ee9cdece49058ba1087193afdad96 368 SUPERFAMILY SSF53756 25 364 7.85E-37 T 31-10-2018 DFR85_04365 624ee9cdece49058ba1087193afdad96 368 Gene3D G3DSA:3.40.50.2000 180 351 6.9E-29 T 31-10-2018 DFR85_03330 beb5589f1cda95704b878bc836ff3001 404 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 6.8E-5 T 31-10-2018 DFR85_03330 beb5589f1cda95704b878bc836ff3001 404 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 277 284 6.8E-5 T 31-10-2018 DFR85_03330 beb5589f1cda95704b878bc836ff3001 404 Gene3D G3DSA:3.30.9.10 72 362 4.9E-52 T 31-10-2018 DFR85_03330 beb5589f1cda95704b878bc836ff3001 404 Pfam PF12831 FAD dependent oxidoreductase 6 158 1.6E-12 T 31-10-2018 IPR039649 Digeranylgeranylglycerophospholipid reductase, N-terminal DFR85_03330 beb5589f1cda95704b878bc836ff3001 404 SUPERFAMILY SSF54373 174 262 9.02E-7 T 31-10-2018 DFR85_03330 beb5589f1cda95704b878bc836ff3001 404 SUPERFAMILY SSF51905 2 349 1.23E-32 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_03330 beb5589f1cda95704b878bc836ff3001 404 Gene3D G3DSA:3.50.50.60 6 346 4.9E-52 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_12080 5068a0a7b01b2e0d35fa2aef2e33eff2 358 Hamap MF_02127 Glucose 1-dehydrogenase [gdh]. 1 357 58.284 T 31-10-2018 IPR026583 Glucose 1-dehydrogenase GO:0005536|GO:0008270|GO:0047936 KEGG: 00030+1.1.1.47 DFR85_12080 5068a0a7b01b2e0d35fa2aef2e33eff2 358 SUPERFAMILY SSF51735 182 322 1.9E-10 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_12080 5068a0a7b01b2e0d35fa2aef2e33eff2 358 Gene3D G3DSA:3.90.180.10 4 340 1.6E-107 T 31-10-2018 DFR85_12080 5068a0a7b01b2e0d35fa2aef2e33eff2 358 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 138 1.8E-19 T 31-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DFR85_12080 5068a0a7b01b2e0d35fa2aef2e33eff2 358 Pfam PF16912 Glucose dehydrogenase C-terminus 144 355 3.6E-27 T 31-10-2018 IPR031640 Glucose dehydrogenase, C-terminal KEGG: 00030+1.1.1.47 DFR85_12080 5068a0a7b01b2e0d35fa2aef2e33eff2 358 SUPERFAMILY SSF50129 1 147 2.36E-29 T 31-10-2018 IPR011032 GroES-like superfamily DFR85_12080 5068a0a7b01b2e0d35fa2aef2e33eff2 358 Gene3D G3DSA:3.40.50.720 145 333 1.6E-107 T 31-10-2018 DFR85_03735 caeb34a91c499b4d94e79ddd0aa04f48 496 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 8 453 8.2E-75 T 31-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 DFR85_12855 62da7696ecfbbd8a965e9923ebacda74 341 SMART SM00933 51 305 2.6E-18 T 31-10-2018 IPR018977 NurA domain DFR85_12855 62da7696ecfbbd8a965e9923ebacda74 341 Pfam PF09376 NurA domain 57 302 2.8E-11 T 31-10-2018 IPR018977 NurA domain DFR85_11865 234bfe097939096955d3ef5d263fdbc5 238 SMART SM00882 4 202 2.3E-4 T 31-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 DFR85_11865 234bfe097939096955d3ef5d263fdbc5 238 Pfam PF01144 Coenzyme A transferase 6 200 1.3E-32 T 31-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 DFR85_11865 234bfe097939096955d3ef5d263fdbc5 238 SUPERFAMILY SSF100950 4 236 6.98E-45 T 31-10-2018 IPR037171 NagB/RpiA transferase-like DFR85_11865 234bfe097939096955d3ef5d263fdbc5 238 Gene3D G3DSA:3.40.1080.10 2 236 5.7E-39 T 31-10-2018 DFR85_01085 9327d853df215fe4d2bd5dbae2d4d58e 444 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 443 9.5E-127 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR85_01085 9327d853df215fe4d2bd5dbae2d4d58e 444 SUPERFAMILY SSF51621 1 318 1.18E-72 T 31-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 DFR85_01085 9327d853df215fe4d2bd5dbae2d4d58e 444 Pfam PF00224 Pyruvate kinase, barrel domain 1 320 3.1E-86 T 31-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR85_01085 9327d853df215fe4d2bd5dbae2d4d58e 444 Gene3D G3DSA:3.20.20.60 5 308 7.5E-102 T 31-10-2018 DFR85_01085 9327d853df215fe4d2bd5dbae2d4d58e 444 PRINTS PR01050 Pyruvate kinase family signature 196 222 5.5E-55 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR85_01085 9327d853df215fe4d2bd5dbae2d4d58e 444 PRINTS PR01050 Pyruvate kinase family signature 223 247 5.5E-55 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR85_01085 9327d853df215fe4d2bd5dbae2d4d58e 444 PRINTS PR01050 Pyruvate kinase family signature 273 291 5.5E-55 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR85_01085 9327d853df215fe4d2bd5dbae2d4d58e 444 PRINTS PR01050 Pyruvate kinase family signature 292 308 5.5E-55 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR85_01085 9327d853df215fe4d2bd5dbae2d4d58e 444 PRINTS PR01050 Pyruvate kinase family signature 169 183 5.5E-55 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR85_01085 9327d853df215fe4d2bd5dbae2d4d58e 444 PRINTS PR01050 Pyruvate kinase family signature 52 68 5.5E-55 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR85_01085 9327d853df215fe4d2bd5dbae2d4d58e 444 PRINTS PR01050 Pyruvate kinase family signature 248 272 5.5E-55 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR85_01085 9327d853df215fe4d2bd5dbae2d4d58e 444 ProSitePatterns PS00110 Pyruvate kinase active site signature. 194 206 - T 31-10-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR85_01085 9327d853df215fe4d2bd5dbae2d4d58e 444 Gene3D G3DSA:2.40.33.10 63 151 7.5E-102 T 31-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR85_01085 9327d853df215fe4d2bd5dbae2d4d58e 444 SUPERFAMILY SSF50800 63 149 6.28E-17 T 31-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily DFR85_01085 9327d853df215fe4d2bd5dbae2d4d58e 444 Gene3D G3DSA:3.40.1380.20 315 444 1.5E-30 T 31-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR85_01085 9327d853df215fe4d2bd5dbae2d4d58e 444 SUPERFAMILY SSF52935 302 443 6.02E-32 T 31-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR85_01085 9327d853df215fe4d2bd5dbae2d4d58e 444 Pfam PF02887 Pyruvate kinase, alpha/beta domain 331 442 3.7E-26 T 31-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR85_03780 f54c58942a545b398cd02c65d197ff15 453 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 36 47 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR85_03780 f54c58942a545b398cd02c65d197ff15 453 Pfam PF13183 4Fe-4S dicluster domain 33 119 3.3E-10 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR85_03780 f54c58942a545b398cd02c65d197ff15 453 Pfam PF02754 Cysteine-rich domain 313 365 0.0017 T 31-10-2018 IPR004017 Cysteine-rich domain DFR85_03780 f54c58942a545b398cd02c65d197ff15 453 Gene3D G3DSA:1.10.1060.10 14 142 1.8E-8 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 DFR85_03780 f54c58942a545b398cd02c65d197ff15 453 SUPERFAMILY SSF46548 26 135 3.84E-14 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 DFR85_03780 f54c58942a545b398cd02c65d197ff15 453 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 105 116 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR85_10685 ddddb587d3291af4714969c491a4ce3e 563 SUPERFAMILY SSF52029 219 385 1.07E-58 T 31-10-2018 IPR027409 GroEL-like apical domain superfamily DFR85_10685 ddddb587d3291af4714969c491a4ce3e 563 SUPERFAMILY SSF54849 154 410 1.19E-23 T 31-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily DFR85_10685 ddddb587d3291af4714969c491a4ce3e 563 SUPERFAMILY SSF48592 16 531 4.58E-87 T 31-10-2018 IPR027413 GroEL-like equatorial domain superfamily DFR85_10685 ddddb587d3291af4714969c491a4ce3e 563 Pfam PF00118 TCP-1/cpn60 chaperonin family 33 533 1.4E-173 T 31-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 DFR85_10685 ddddb587d3291af4714969c491a4ce3e 563 Gene3D G3DSA:3.30.260.10 145 412 6.7E-202 T 31-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily DFR85_10685 ddddb587d3291af4714969c491a4ce3e 563 Gene3D G3DSA:3.50.7.10 223 377 6.7E-202 T 31-10-2018 IPR027409 GroEL-like apical domain superfamily DFR85_10685 ddddb587d3291af4714969c491a4ce3e 563 ProSitePatterns PS00750 Chaperonins TCP-1 signature 1. 38 50 - T 31-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR85_10685 ddddb587d3291af4714969c491a4ce3e 563 ProSitePatterns PS00995 Chaperonins TCP-1 signature 3. 87 95 - T 31-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR85_10685 ddddb587d3291af4714969c491a4ce3e 563 ProSitePatterns PS00751 Chaperonins TCP-1 signature 2. 59 75 - T 31-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR85_10685 ddddb587d3291af4714969c491a4ce3e 563 Gene3D G3DSA:1.10.560.10 26 530 6.7E-202 T 31-10-2018 IPR027413 GroEL-like equatorial domain superfamily DFR85_10685 ddddb587d3291af4714969c491a4ce3e 563 TIGRFAM TIGR02339 thermosome_arch: thermosome, various subunits, archaeal 6 532 1.4E-241 T 31-10-2018 IPR012714 Thermosome, archaeal GO:0005524|GO:0006457|GO:0051082 DFR85_10685 ddddb587d3291af4714969c491a4ce3e 563 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 87 106 5.1E-33 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR85_10685 ddddb587d3291af4714969c491a4ce3e 563 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 380 402 5.1E-33 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR85_10685 ddddb587d3291af4714969c491a4ce3e 563 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 414 426 5.1E-33 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR85_10685 ddddb587d3291af4714969c491a4ce3e 563 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 57 75 5.1E-33 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR85_10685 ddddb587d3291af4714969c491a4ce3e 563 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 35 51 5.1E-33 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR85_11060 9df0b1ded2a29fe9674ff0e6793ef822 345 Pfam PF04454 Encapsulating protein for peroxidase 147 325 5.5E-13 T 31-10-2018 IPR007544 Encapsulating protein for peroxidase GO:0008233|GO:0042742 DFR85_11060 9df0b1ded2a29fe9674ff0e6793ef822 345 Gene3D G3DSA:3.30.2320.10 219 315 1.3E-12 T 31-10-2018 DFR85_11060 9df0b1ded2a29fe9674ff0e6793ef822 345 SUPERFAMILY SSF47240 7 84 4.19E-13 T 31-10-2018 IPR009078 Ferritin-like superfamily DFR85_02360 21bc5bf272391dca6cee413f8fe601a4 390 SUPERFAMILY SSF53187 5 389 1.92E-86 T 31-10-2018 DFR85_02360 21bc5bf272391dca6cee413f8fe601a4 390 Pfam PF01546 Peptidase family M20/M25/M40 76 385 8.6E-34 T 31-10-2018 IPR002933 Peptidase M20 GO:0016787 DFR85_02360 21bc5bf272391dca6cee413f8fe601a4 390 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 17 378 1.2E-129 T 31-10-2018 IPR017439 Amidohydrolase GO:0016787 DFR85_02360 21bc5bf272391dca6cee413f8fe601a4 390 SUPERFAMILY SSF55031 187 294 9.81E-30 T 31-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain DFR85_02360 21bc5bf272391dca6cee413f8fe601a4 390 PIRSF PIRSF005962 2 390 1.3E-124 T 31-10-2018 IPR017439 Amidohydrolase GO:0016787 DFR85_02360 21bc5bf272391dca6cee413f8fe601a4 390 Gene3D G3DSA:3.40.630.10 17 375 4.4E-139 T 31-10-2018 DFR85_02360 21bc5bf272391dca6cee413f8fe601a4 390 Pfam PF07687 Peptidase dimerisation domain 188 282 1.1E-12 T 31-10-2018 IPR011650 Peptidase M20, dimerisation domain DFR85_02360 21bc5bf272391dca6cee413f8fe601a4 390 Gene3D G3DSA:3.30.70.360 184 299 4.4E-139 T 31-10-2018 DFR85_08555 5eace79f0f97c496cee15809e9a4b84e 236 Gene3D G3DSA:1.20.120.1220 13 233 1.8E-12 T 31-10-2018 DFR85_08555 5eace79f0f97c496cee15809e9a4b84e 236 Pfam PF06847 Archaeal Peptidase A24 C-terminus Type II 142 233 1.5E-21 T 31-10-2018 IPR009655 Preflagellin peptidase, C-terminal DFR85_08555 5eace79f0f97c496cee15809e9a4b84e 236 Pfam PF01478 Type IV leader peptidase family 11 112 3.0E-8 T 31-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 DFR85_08555 5eace79f0f97c496cee15809e9a4b84e 236 Gene3D G3DSA:3.30.1360.160 122 217 1.8E-12 T 31-10-2018 DFR85_04135 0760d7794b4abfcf5319e9260cd1f8ed 333 SUPERFAMILY SSF161098 103 314 1.16E-12 T 31-10-2018 IPR035906 MetI-like superfamily DFR85_04135 0760d7794b4abfcf5319e9260cd1f8ed 333 Gene3D G3DSA:1.10.3720.10 96 326 7.5E-12 T 31-10-2018 IPR035906 MetI-like superfamily DFR85_04135 0760d7794b4abfcf5319e9260cd1f8ed 333 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 125 332 2.0E-35 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 DFR85_08590 017515379d9e7106e38b7c6d3fe3d3d5 291 Gene3D G3DSA:3.50.50.100 2 94 4.3E-8 T 31-10-2018 DFR85_08590 017515379d9e7106e38b7c6d3fe3d3d5 291 SUPERFAMILY SSF51905 3 223 2.32E-12 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_08590 017515379d9e7106e38b7c6d3fe3d3d5 291 Gene3D G3DSA:3.50.50.100 146 289 1.4E-5 T 31-10-2018 DFR85_00335 ad75c781b8103358062433e04324aac6 325 SUPERFAMILY SSF50129 2 168 1.02E-39 T 31-10-2018 IPR011032 GroES-like superfamily DFR85_00335 ad75c781b8103358062433e04324aac6 325 SUPERFAMILY SSF51735 142 297 1.97E-26 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_00335 ad75c781b8103358062433e04324aac6 325 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 131 2.7E-26 T 31-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DFR85_00335 ad75c781b8103358062433e04324aac6 325 Gene3D G3DSA:3.40.50.720 143 275 4.7E-71 T 31-10-2018 DFR85_00335 ad75c781b8103358062433e04324aac6 325 Gene3D G3DSA:3.90.180.10 16 310 4.7E-71 T 31-10-2018 DFR85_00335 ad75c781b8103358062433e04324aac6 325 SMART SM00829 10 323 5.8E-7 T 31-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DFR85_00335 ad75c781b8103358062433e04324aac6 325 Pfam PF00107 Zinc-binding dehydrogenase 174 285 4.6E-15 T 31-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DFR85_07010 7003406d7e8a774e88d16c4e6add74a2 198 Hamap MF_01337_A 50S ribosomal protein L18 [rplR]. 6 193 38.64 T 31-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07010 7003406d7e8a774e88d16c4e6add74a2 198 Gene3D G3DSA:3.30.420.100 3 197 2.9E-59 T 31-10-2018 DFR85_07010 7003406d7e8a774e88d16c4e6add74a2 198 SUPERFAMILY SSF53137 5 194 1.2E-55 T 31-10-2018 DFR85_07010 7003406d7e8a774e88d16c4e6add74a2 198 Pfam PF17144 Ribosomal large subunit proteins 60S L5, and 50S L18 7 95 3.5E-20 T 31-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07010 7003406d7e8a774e88d16c4e6add74a2 198 Pfam PF14204 Ribosomal L18 C-terminal region 141 194 5.0E-9 T 31-10-2018 IPR025607 Ribosomal protein L5 eukaryotic/L18 archaeal, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07945 9a8531b077eb1cda610ae90829360cc9 176 SUPERFAMILY SSF50249 81 173 7.09E-20 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR85_07945 9a8531b077eb1cda610ae90829360cc9 176 Gene3D G3DSA:3.30.1490.120 1 81 2.3E-28 T 31-10-2018 IPR036898 RNA polymerase Rpb7-like, N-terminal domain superfamily GO:0003899|GO:0006351 DFR85_07945 9a8531b077eb1cda610ae90829360cc9 176 SUPERFAMILY SSF88798 1 77 6.93E-20 T 31-10-2018 IPR036898 RNA polymerase Rpb7-like, N-terminal domain superfamily GO:0003899|GO:0006351 DFR85_07945 9a8531b077eb1cda610ae90829360cc9 176 TIGRFAM TIGR00448 rpoE: DNA-directed RNA polymerase 1 175 6.2E-53 T 31-10-2018 IPR004519 DNA-directed RNA polymerase, subunit E/RPC8 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-1834949|Reactome: R-HSA-73780|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071 DFR85_07945 9a8531b077eb1cda610ae90829360cc9 176 Gene3D G3DSA:2.40.50.140 82 176 2.1E-23 T 31-10-2018 DFR85_07945 9a8531b077eb1cda610ae90829360cc9 176 Pfam PF00575 S1 RNA binding domain 82 149 7.1E-15 T 31-10-2018 IPR003029 S1 domain GO:0003676 DFR85_07945 9a8531b077eb1cda610ae90829360cc9 176 Pfam PF03876 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 10 77 9.4E-15 T 31-10-2018 IPR005576 RNA polymerase Rpb7, N-terminal GO:0003899|GO:0006351 DFR85_07945 9a8531b077eb1cda610ae90829360cc9 176 SMART SM00316 80 165 1.1E-14 T 31-10-2018 IPR022967 RNA-binding domain, S1 DFR85_09210 2aa65c41701c9b43896af0a4bd4b2e86 315 Gene3D G3DSA:3.40.50.720 1 187 1.8E-56 T 31-10-2018 DFR85_09210 2aa65c41701c9b43896af0a4bd4b2e86 315 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 4 182 1.3E-54 T 31-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 DFR85_09210 2aa65c41701c9b43896af0a4bd4b2e86 315 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 187 271 3.3E-18 T 31-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 DFR85_09210 2aa65c41701c9b43896af0a4bd4b2e86 315 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 184 208 - T 31-10-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 DFR85_09210 2aa65c41701c9b43896af0a4bd4b2e86 315 PIRSF PIRSF000105 1 312 9.1E-75 T 31-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 DFR85_09210 2aa65c41701c9b43896af0a4bd4b2e86 315 SUPERFAMILY SSF51735 1 184 1.26E-51 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_09210 2aa65c41701c9b43896af0a4bd4b2e86 315 SUPERFAMILY SSF48179 187 261 6.38E-14 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 DFR85_09210 2aa65c41701c9b43896af0a4bd4b2e86 315 Gene3D G3DSA:1.10.1040.10 188 312 4.1E-35 T 31-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 DFR85_01205 edb8564954ab5b23debfb12260490223 333 SUPERFAMILY SSF51735 144 304 1.54E-34 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_01205 edb8564954ab5b23debfb12260490223 333 Pfam PF00107 Zinc-binding dehydrogenase 174 295 1.4E-23 T 31-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DFR85_01205 edb8564954ab5b23debfb12260490223 333 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 163 184 - T 31-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 DFR85_01205 edb8564954ab5b23debfb12260490223 333 Gene3D G3DSA:3.90.180.10 1 333 3.3E-97 T 31-10-2018 DFR85_01205 edb8564954ab5b23debfb12260490223 333 SUPERFAMILY SSF50129 1 170 1.28E-48 T 31-10-2018 IPR011032 GroES-like superfamily DFR85_01205 edb8564954ab5b23debfb12260490223 333 SMART SM00829 8 331 3.1E-12 T 31-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DFR85_01205 edb8564954ab5b23debfb12260490223 333 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 31-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 DFR85_01205 edb8564954ab5b23debfb12260490223 333 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 132 1.1E-27 T 31-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DFR85_13425 5586dbb099bd55c86f97426902761ec4 95 SMART SM00748 4 85 2.1E-4 T 31-10-2018 IPR007842 HEPN domain DFR85_13425 5586dbb099bd55c86f97426902761ec4 95 SUPERFAMILY SSF81593 3 89 1.96E-13 T 31-10-2018 DFR85_13425 5586dbb099bd55c86f97426902761ec4 95 Gene3D G3DSA:1.20.120.330 1 93 1.5E-14 T 31-10-2018 DFR85_13425 5586dbb099bd55c86f97426902761ec4 95 Pfam PF05168 HEPN domain 3 89 2.1E-16 T 31-10-2018 IPR007842 HEPN domain DFR85_02320 02f3387bb1798d98344982c3d1c50eba 134 SUPERFAMILY SSF52980 6 126 1.43E-31 T 31-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 DFR85_02320 02f3387bb1798d98344982c3d1c50eba 134 Pfam PF01870 Archaeal holliday junction resolvase (hjc) 9 102 8.4E-29 T 31-10-2018 IPR002732 Holliday junction resolvase Hjc DFR85_02320 02f3387bb1798d98344982c3d1c50eba 134 ProDom PD015874 RESOLVASE HOLLIDAY JUNCTION ARCHAEAL HOLLIDAY-JUNCTION TYPE MJ0497 ORF-C21_024 PF1503 NEQ424 10 133 8.0E-40 T 31-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal DFR85_02320 02f3387bb1798d98344982c3d1c50eba 134 Gene3D G3DSA:3.40.1350.10 1 134 2.1E-44 T 31-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 DFR85_02320 02f3387bb1798d98344982c3d1c50eba 134 PIRSF PIRSF004985 1 132 4.1E-35 T 31-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal DFR85_15405 6b6dca32a50d97bb08585298319791ed 138 Gene3D G3DSA:3.40.50.620 1 138 2.2E-32 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR85_15405 6b6dca32a50d97bb08585298319791ed 138 Pfam PF00582 Universal stress protein family 2 137 5.5E-30 T 31-10-2018 IPR006016 UspA DFR85_15405 6b6dca32a50d97bb08585298319791ed 138 SUPERFAMILY SSF52402 2 137 3.68E-31 T 31-10-2018 DFR85_15405 6b6dca32a50d97bb08585298319791ed 138 PRINTS PR01438 Universal stress protein signature 97 109 7.9E-18 T 31-10-2018 IPR006015 Universal stress protein A DFR85_15405 6b6dca32a50d97bb08585298319791ed 138 PRINTS PR01438 Universal stress protein signature 115 137 7.9E-18 T 31-10-2018 IPR006015 Universal stress protein A DFR85_15405 6b6dca32a50d97bb08585298319791ed 138 PRINTS PR01438 Universal stress protein signature 2 20 7.9E-18 T 31-10-2018 IPR006015 Universal stress protein A DFR85_09820 d4547e78901a8ab84b4a5716dc5e94ae 344 Gene3D G3DSA:3.40.50.720 93 255 5.5E-17 T 31-10-2018 DFR85_09820 d4547e78901a8ab84b4a5716dc5e94ae 344 SMART SM00830 8 88 4.6E-22 T 31-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 DFR85_09820 d4547e78901a8ab84b4a5716dc5e94ae 344 SUPERFAMILY SSF48600 3 87 2.75E-20 T 31-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 DFR85_09820 d4547e78901a8ab84b4a5716dc5e94ae 344 Gene3D G3DSA:1.20.59.10 1 92 5.6E-20 T 31-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 DFR85_09820 d4547e78901a8ab84b4a5716dc5e94ae 344 SUPERFAMILY SSF51735 93 270 5.18E-18 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_09820 d4547e78901a8ab84b4a5716dc5e94ae 344 TIGRFAM TIGR01791 CM_archaeal: chorismate mutase 4 84 8.3E-22 T 31-10-2018 IPR010950 Chorismate mutase, archaeal KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 DFR85_09820 d4547e78901a8ab84b4a5716dc5e94ae 344 Pfam PF01817 Chorismate mutase type II 8 85 9.0E-16 T 31-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 DFR85_09820 d4547e78901a8ab84b4a5716dc5e94ae 344 Pfam PF02153 Prephenate dehydrogenase 114 309 4.5E-18 T 31-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 DFR85_09820 d4547e78901a8ab84b4a5716dc5e94ae 344 SUPERFAMILY SSF48179 250 337 7.14E-6 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 DFR85_09455 cf9dc2464fcf816d66e1ac3f1c61ac3f 285 SUPERFAMILY SSF54913 213 284 5.67E-13 T 31-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta DFR85_09455 cf9dc2464fcf816d66e1ac3f1c61ac3f 285 Gene3D G3DSA:3.30.70.120 213 285 1.0E-14 T 31-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal DFR85_09455 cf9dc2464fcf816d66e1ac3f1c61ac3f 285 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 143 164 - T 31-10-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 DFR85_09455 cf9dc2464fcf816d66e1ac3f1c61ac3f 285 SUPERFAMILY SSF53850 1 210 7.09E-63 T 31-10-2018 DFR85_09455 cf9dc2464fcf816d66e1ac3f1c61ac3f 285 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 190 284 6.4E-23 T 31-10-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 DFR85_09455 cf9dc2464fcf816d66e1ac3f1c61ac3f 285 Pfam PF01634 ATP phosphoribosyltransferase 49 205 4.0E-47 T 31-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 DFR85_09455 cf9dc2464fcf816d66e1ac3f1c61ac3f 285 Pfam PF08029 HisG, C-terminal domain 210 282 1.3E-15 T 31-10-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 DFR85_09455 cf9dc2464fcf816d66e1ac3f1c61ac3f 285 Gene3D G3DSA:3.40.190.10 2 193 9.8E-65 T 31-10-2018 DFR85_09455 cf9dc2464fcf816d66e1ac3f1c61ac3f 285 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 1 285 30.812 T 31-10-2018 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 DFR85_09455 cf9dc2464fcf816d66e1ac3f1c61ac3f 285 Gene3D G3DSA:3.40.190.10 88 178 9.8E-65 T 31-10-2018 DFR85_09455 cf9dc2464fcf816d66e1ac3f1c61ac3f 285 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 1 183 6.8E-64 T 31-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 DFR85_01525 e3b60f25ce203c8c48a4f6125e2b22e2 280 SUPERFAMILY SSF52402 11 259 9.61E-73 T 31-10-2018 DFR85_01525 e3b60f25ce203c8c48a4f6125e2b22e2 280 TIGRFAM TIGR00552 nadE: NAD+ synthetase 18 262 8.9E-74 T 31-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 DFR85_01525 e3b60f25ce203c8c48a4f6125e2b22e2 280 Pfam PF02540 NAD synthase 21 259 6.2E-78 T 31-10-2018 IPR022310 NAD/GMP synthase DFR85_01525 e3b60f25ce203c8c48a4f6125e2b22e2 280 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 14 262 49.488 T 31-10-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 DFR85_01525 e3b60f25ce203c8c48a4f6125e2b22e2 280 Gene3D G3DSA:3.40.50.620 11 264 4.1E-79 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR85_10915 5cd9832ddbf4574cc2af9c4590174b12 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 100 111 1.3E-36 T 31-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 DFR85_10915 5cd9832ddbf4574cc2af9c4590174b12 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 129 146 1.3E-36 T 31-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 DFR85_10915 5cd9832ddbf4574cc2af9c4590174b12 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 202 219 1.3E-36 T 31-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 DFR85_10915 5cd9832ddbf4574cc2af9c4590174b12 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 147 162 1.3E-36 T 31-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 DFR85_10915 5cd9832ddbf4574cc2af9c4590174b12 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 226 247 1.3E-36 T 31-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 DFR85_10915 5cd9832ddbf4574cc2af9c4590174b12 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 258 274 1.3E-36 T 31-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 DFR85_10915 5cd9832ddbf4574cc2af9c4590174b12 386 Gene3D G3DSA:3.40.1360.10 156 386 4.2E-85 T 31-10-2018 DFR85_10915 5cd9832ddbf4574cc2af9c4590174b12 386 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 42 62 2.4E-45 T 31-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 DFR85_10915 5cd9832ddbf4574cc2af9c4590174b12 386 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 123 140 2.4E-45 T 31-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 DFR85_10915 5cd9832ddbf4574cc2af9c4590174b12 386 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 176 194 2.4E-45 T 31-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 DFR85_10915 5cd9832ddbf4574cc2af9c4590174b12 386 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 232 252 2.4E-45 T 31-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 DFR85_10915 5cd9832ddbf4574cc2af9c4590174b12 386 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 356 379 2.4E-45 T 31-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 DFR85_10915 5cd9832ddbf4574cc2af9c4590174b12 386 Gene3D G3DSA:1.10.10.10 1 155 1.5E-58 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_10915 5cd9832ddbf4574cc2af9c4590174b12 386 SUPERFAMILY SSF56726 75 385 1.26E-86 T 31-10-2018 IPR036078 Spo11/DNA topoisomerase VI subunit A superfamily GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 DFR85_10915 5cd9832ddbf4574cc2af9c4590174b12 386 Pfam PF04406 Type IIB DNA topoisomerase 76 152 1.2E-19 T 31-10-2018 IPR013049 Spo11/DNA topoisomerase VI, subunit A, N-terminal GO:0003677|GO:0003824|GO:0005524|GO:0005694|GO:0006259 Reactome: R-HSA-912446 DFR85_10915 5cd9832ddbf4574cc2af9c4590174b12 386 Hamap MF_00132 Type 2 DNA topoisomerase 6 subunit A [top6A]. 10 385 38.711 T 31-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 DFR85_10210 f414532a7763f3abe0ce16ef7371f219 349 TIGRFAM TIGR00748 HMG_CoA_syn_Arc: putative hydroxymethylglutaryl-CoA synthase 3 346 1.2E-133 T 31-10-2018 IPR004656 Putative condensing enzyme FabH-related DFR85_10210 f414532a7763f3abe0ce16ef7371f219 349 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 107 142 3.9E-5 T 31-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 DFR85_10210 f414532a7763f3abe0ce16ef7371f219 349 Gene3D G3DSA:3.40.47.10 2 349 2.6E-74 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR85_10210 f414532a7763f3abe0ce16ef7371f219 349 SUPERFAMILY SSF53901 4 166 1.56E-31 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR85_10210 f414532a7763f3abe0ce16ef7371f219 349 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 219 299 2.3E-10 T 31-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 DFR85_10210 f414532a7763f3abe0ce16ef7371f219 349 Hamap MF_01409 UPF0219 protein . 2 346 55.915 T 31-10-2018 IPR004656 Putative condensing enzyme FabH-related DFR85_10210 f414532a7763f3abe0ce16ef7371f219 349 SUPERFAMILY SSF53901 171 346 8.42E-43 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR85_09280 385fb5802158740b56172a1de239874b 222 PIRSF PIRSF001586 1 221 7.9E-75 T 31-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 DFR85_09280 385fb5802158740b56172a1de239874b 222 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 2 220 3.0E-92 T 31-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 DFR85_09280 385fb5802158740b56172a1de239874b 222 SUPERFAMILY SSF52317 2 218 4.16E-64 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like DFR85_09280 385fb5802158740b56172a1de239874b 222 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 204 1.2E-43 T 31-10-2018 DFR85_09280 385fb5802158740b56172a1de239874b 222 SMART SM01211 1 222 5.1E-94 T 31-10-2018 DFR85_09280 385fb5802158740b56172a1de239874b 222 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 1 222 38.271 T 31-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 DFR85_09280 385fb5802158740b56172a1de239874b 222 Gene3D G3DSA:3.40.50.880 1 220 3.5E-66 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like DFR85_09540 52d1466a00d977a1dc496f552f841f41 332 PIRSF PIRSF000116 199 330 1.2E-10 T 31-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 DFR85_09540 52d1466a00d977a1dc496f552f841f41 332 PIRSF PIRSF000116 4 207 6.4E-44 T 31-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 DFR85_09540 52d1466a00d977a1dc496f552f841f41 332 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 15 328 3.4E-124 T 31-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 DFR85_09540 52d1466a00d977a1dc496f552f841f41 332 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 184 325 3.4E-50 T 31-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 DFR85_09540 52d1466a00d977a1dc496f552f841f41 332 SUPERFAMILY SSF51735 3 183 3.02E-71 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_09540 52d1466a00d977a1dc496f552f841f41 332 Gene3D G3DSA:1.10.3730.40 183 331 1.5E-53 T 31-10-2018 DFR85_09540 52d1466a00d977a1dc496f552f841f41 332 Gene3D G3DSA:3.40.50.720 1 182 4.9E-74 T 31-10-2018 DFR85_09540 52d1466a00d977a1dc496f552f841f41 332 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 2 329 38.945 T 31-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 DFR85_09540 52d1466a00d977a1dc496f552f841f41 332 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 15 178 2.1E-74 T 31-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 DFR85_09540 52d1466a00d977a1dc496f552f841f41 332 SUPERFAMILY SSF48179 184 325 1.09E-54 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 DFR85_01585 da7d472266df066269edf40f6e8775e4 409 Gene3D G3DSA:3.40.718.10 1 408 3.4E-167 T 31-10-2018 DFR85_01585 da7d472266df066269edf40f6e8775e4 409 SUPERFAMILY SSF53659 3 404 6.53E-135 T 31-10-2018 DFR85_01585 da7d472266df066269edf40f6e8775e4 409 SMART SM01329 25 401 8.4E-166 T 31-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 DFR85_01585 da7d472266df066269edf40f6e8775e4 409 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 26 399 1.8E-106 T 31-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 DFR85_10955 aa9c8d7f28dc24b511109388f57f2302 226 SUPERFAMILY SSF53633 3 224 1.1E-38 T 31-10-2018 IPR036393 Acetylglutamate kinase-like superfamily DFR85_10955 aa9c8d7f28dc24b511109388f57f2302 226 Hamap MF_01220_A Uridylate kinase [pyrH]. 1 225 36.173 T 31-10-2018 IPR011818 Uridylate kinase, archaeal/spirochete, putative GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 DFR85_10955 aa9c8d7f28dc24b511109388f57f2302 226 Pfam PF00696 Amino acid kinase family 3 203 1.3E-25 T 31-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 DFR85_10955 aa9c8d7f28dc24b511109388f57f2302 226 Gene3D G3DSA:3.40.1160.10 1 226 1.6E-55 T 31-10-2018 IPR036393 Acetylglutamate kinase-like superfamily DFR85_10955 aa9c8d7f28dc24b511109388f57f2302 226 PIRSF PIRSF005650 1 226 8.8E-54 T 31-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 DFR85_10955 aa9c8d7f28dc24b511109388f57f2302 226 TIGRFAM TIGR02076 pyrH_arch: putative uridylate kinase 4 224 1.9E-83 T 31-10-2018 IPR011818 Uridylate kinase, archaeal/spirochete, putative GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 DFR85_09660 71cb07caca46a18889ae0b95c57a5af0 342 SUPERFAMILY SSF55347 178 284 7.46E-26 T 31-10-2018 DFR85_09660 71cb07caca46a18889ae0b95c57a5af0 342 Gene3D G3DSA:3.40.50.720 2 320 1.7E-74 T 31-10-2018 DFR85_09660 71cb07caca46a18889ae0b95c57a5af0 342 SUPERFAMILY SSF51735 2 322 1.0E-56 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_09660 71cb07caca46a18889ae0b95c57a5af0 342 Pfam PF01658 Myo-inositol-1-phosphate synthase 180 283 1.9E-20 T 31-10-2018 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 DFR85_09660 71cb07caca46a18889ae0b95c57a5af0 342 Gene3D G3DSA:3.30.360.10 179 284 1.7E-74 T 31-10-2018 DFR85_02485 3c01e37e8bfd0f1c1e6e6b8c7e268a70 59 Pfam PF06348 Protein of unknown function (DUF1059) 2 58 1.8E-19 T 31-10-2018 IPR009409 Protein of unknown function DUF1059 DFR85_11380 406b2dea30ca518167bfb82c8f364c79 337 SUPERFAMILY SSF52768 2 306 1.63E-72 T 31-10-2018 IPR023696 Ureohydrolase domain superfamily DFR85_11380 406b2dea30ca518167bfb82c8f364c79 337 Gene3D G3DSA:3.40.800.20 3 331 1.1E-67 T 31-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 DFR85_11380 406b2dea30ca518167bfb82c8f364c79 337 Pfam PF00850 Histone deacetylase domain 26 289 5.2E-55 T 31-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 DFR85_11380 406b2dea30ca518167bfb82c8f364c79 337 PRINTS PR01270 Histone deacetylase superfamily signature 151 166 5.6E-15 T 31-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 DFR85_11380 406b2dea30ca518167bfb82c8f364c79 337 PRINTS PR01270 Histone deacetylase superfamily signature 119 142 5.6E-15 T 31-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 DFR85_11380 406b2dea30ca518167bfb82c8f364c79 337 PRINTS PR01270 Histone deacetylase superfamily signature 234 244 5.6E-15 T 31-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 DFR85_09520 6ac607a29cbfbe419b0bedc5a0caaf48 265 Gene3D G3DSA:1.10.1580.10 164 247 2.6E-8 T 31-10-2018 IPR023179 GTP-binding protein, orthogonal bundle domain superfamily DFR85_09520 6ac607a29cbfbe419b0bedc5a0caaf48 265 SUPERFAMILY SSF52540 4 164 9.66E-36 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_09520 6ac607a29cbfbe419b0bedc5a0caaf48 265 Gene3D G3DSA:3.40.50.300 4 160 6.6E-41 T 31-10-2018 DFR85_09520 6ac607a29cbfbe419b0bedc5a0caaf48 265 Pfam PF01926 50S ribosome-binding GTPase 101 191 2.0E-12 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 DFR85_09520 6ac607a29cbfbe419b0bedc5a0caaf48 265 PIRSF PIRSF006230 1 258 2.6E-53 T 31-10-2018 IPR016478 GTPase, MTG1 DFR85_08835 80d78660f9215d014df82d005e634df2 343 SMART SM01194 1 123 1.4E-37 T 31-10-2018 IPR005140 eRF1 domain 1/Pelota-like DFR85_08835 80d78660f9215d014df82d005e634df2 343 Hamap MF_01853 Protein pelota homolog [pelA]. 2 342 32.519 T 31-10-2018 IPR023521 Translation release factor pelota, archaea GO:0070481|GO:0070966|GO:0071025 DFR85_08835 80d78660f9215d014df82d005e634df2 343 SUPERFAMILY SSF55315 234 343 1.53E-26 T 31-10-2018 IPR029064 50S ribosomal protein L30e-like DFR85_08835 80d78660f9215d014df82d005e634df2 343 TIGRFAM TIGR00111 pelota: mRNA surveillance protein pelota 1 342 3.0E-63 T 31-10-2018 IPR004405 Translation release factor pelota GO:0070481|GO:0070966|GO:0071025 DFR85_08835 80d78660f9215d014df82d005e634df2 343 SUPERFAMILY SSF53137 124 238 4.1E-9 T 31-10-2018 DFR85_08835 80d78660f9215d014df82d005e634df2 343 Pfam PF03465 eRF1 domain 3 244 342 1.8E-21 T 31-10-2018 IPR005142 eRF1 domain 3 DFR85_08835 80d78660f9215d014df82d005e634df2 343 Gene3D G3DSA:3.30.1330.30 241 343 2.3E-31 T 31-10-2018 IPR029064 50S ribosomal protein L30e-like DFR85_08835 80d78660f9215d014df82d005e634df2 343 SUPERFAMILY SSF159065 1 119 9.29E-32 T 31-10-2018 IPR038069 Pelota/DOM34, N-terminal domain DFR85_08835 80d78660f9215d014df82d005e634df2 343 Gene3D G3DSA:2.30.30.870 1 124 4.5E-39 T 31-10-2018 IPR038069 Pelota/DOM34, N-terminal domain DFR85_08835 80d78660f9215d014df82d005e634df2 343 Pfam PF03463 eRF1 domain 1 8 118 1.3E-22 T 31-10-2018 IPR005140 eRF1 domain 1/Pelota-like DFR85_08835 80d78660f9215d014df82d005e634df2 343 Gene3D G3DSA:3.30.420.60 125 240 2.1E-23 T 31-10-2018 DFR85_10920 b61c06b116b4881d6a22d230f4c2a5cc 131 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 8 39 1.6E-7 T 31-10-2018 IPR013185 Translation elongation factor, KOW-like DFR85_10920 b61c06b116b4881d6a22d230f4c2a5cc 131 SUPERFAMILY SSF50104 3 77 1.1E-21 T 31-10-2018 IPR008991 Translation protein SH3-like domain superfamily DFR85_10920 b61c06b116b4881d6a22d230f4c2a5cc 131 ProSitePatterns PS00302 Eukaryotic initiation factor 5A hypusine signature. 34 41 - T 31-10-2018 IPR019769 Translation elongation factor, IF5A, hypusine site GO:0003723|GO:0003746|GO:0043022|GO:0045901|GO:0045905 DFR85_10920 b61c06b116b4881d6a22d230f4c2a5cc 131 Gene3D G3DSA:2.30.30.30 1 68 5.6E-29 T 31-10-2018 IPR014722 Ribosomal protein L2, domain 2 DFR85_10920 b61c06b116b4881d6a22d230f4c2a5cc 131 PIRSF PIRSF003025 1 131 1.4E-46 T 31-10-2018 IPR001884 Translation elongation factor IF5A-like GO:0003723|GO:0003746|GO:0043022|GO:0045901 DFR85_10920 b61c06b116b4881d6a22d230f4c2a5cc 131 Pfam PF01287 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold 70 131 8.0E-7 T 31-10-2018 IPR020189 Translation elongation factor, IF5A C-terminal GO:0003723|GO:0003746|GO:0006452|GO:0043022|GO:0045901|GO:0045905 DFR85_10920 b61c06b116b4881d6a22d230f4c2a5cc 131 SMART SM01376 69 131 1.6E-20 T 31-10-2018 IPR020189 Translation elongation factor, IF5A C-terminal GO:0003723|GO:0003746|GO:0006452|GO:0043022|GO:0045901|GO:0045905 DFR85_10920 b61c06b116b4881d6a22d230f4c2a5cc 131 TIGRFAM TIGR00037 eIF_5A: translation elongation factor IF5A 7 131 1.6E-41 T 31-10-2018 IPR001884 Translation elongation factor IF5A-like GO:0003723|GO:0003746|GO:0043022|GO:0045901 DFR85_10920 b61c06b116b4881d6a22d230f4c2a5cc 131 SUPERFAMILY SSF50249 69 130 1.33E-12 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR85_10920 b61c06b116b4881d6a22d230f4c2a5cc 131 Hamap MF_00085 Translation initiation factor 5A [eif5a]. 2 130 33.21 T 31-10-2018 IPR022847 Translation elongation factor IF5A, archaeal DFR85_10920 b61c06b116b4881d6a22d230f4c2a5cc 131 Gene3D G3DSA:2.40.50.140 69 131 1.1E-25 T 31-10-2018 DFR85_03835 17931a6451b98e4498c3c746ea380c29 443 SMART SM00382 38 230 1.4E-4 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_03835 17931a6451b98e4498c3c746ea380c29 443 SUPERFAMILY SSF52540 32 258 2.37E-13 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_03835 17931a6451b98e4498c3c746ea380c29 443 Gene3D G3DSA:3.40.50.300 17 212 2.7E-7 T 31-10-2018 DFR85_15395 ecb1ccfc185205d072a059fd2669c155 127 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 23 56 6.2E-11 T 31-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal DFR85_15395 ecb1ccfc185205d072a059fd2669c155 127 SUPERFAMILY SSF50249 18 117 1.7E-22 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR85_15395 ecb1ccfc185205d072a059fd2669c155 127 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 61 116 1.2E-7 T 31-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal DFR85_15395 ecb1ccfc185205d072a059fd2669c155 127 Gene3D G3DSA:1.10.12.20 9 59 1.6E-11 T 31-10-2018 DFR85_07780 74f2226b56c1bb72b21c2ec1e7eeb8db 435 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 60 75 - T 31-10-2018 IPR031157 Tr-type G domain, conserved site DFR85_07780 74f2226b56c1bb72b21c2ec1e7eeb8db 435 SUPERFAMILY SSF52540 1 248 1.12E-69 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_07780 74f2226b56c1bb72b21c2ec1e7eeb8db 435 Gene3D G3DSA:2.40.30.10 228 321 1.2E-39 T 31-10-2018 DFR85_07780 74f2226b56c1bb72b21c2ec1e7eeb8db 435 SUPERFAMILY SSF50447 225 321 1.87E-29 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily DFR85_07780 74f2226b56c1bb72b21c2ec1e7eeb8db 435 SUPERFAMILY SSF50465 324 428 7.91E-40 T 31-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal DFR85_07780 74f2226b56c1bb72b21c2ec1e7eeb8db 435 Pfam PF03143 Elongation factor Tu C-terminal domain 321 427 1.3E-37 T 31-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal DFR85_07780 74f2226b56c1bb72b21c2ec1e7eeb8db 435 PRINTS PR00315 GTP-binding elongation factor signature 103 114 2.6E-21 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR85_07780 74f2226b56c1bb72b21c2ec1e7eeb8db 435 PRINTS PR00315 GTP-binding elongation factor signature 147 156 2.6E-21 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR85_07780 74f2226b56c1bb72b21c2ec1e7eeb8db 435 PRINTS PR00315 GTP-binding elongation factor signature 67 75 2.6E-21 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR85_07780 74f2226b56c1bb72b21c2ec1e7eeb8db 435 PRINTS PR00315 GTP-binding elongation factor signature 87 97 2.6E-21 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR85_07780 74f2226b56c1bb72b21c2ec1e7eeb8db 435 PRINTS PR00315 GTP-binding elongation factor signature 8 21 2.6E-21 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR85_07780 74f2226b56c1bb72b21c2ec1e7eeb8db 435 Gene3D G3DSA:2.40.30.10 322 428 5.5E-43 T 31-10-2018 DFR85_07780 74f2226b56c1bb72b21c2ec1e7eeb8db 435 Pfam PF03144 Elongation factor Tu domain 2 247 312 4.3E-18 T 31-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 DFR85_07780 74f2226b56c1bb72b21c2ec1e7eeb8db 435 Pfam PF00009 Elongation factor Tu GTP binding domain 4 213 1.6E-49 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR85_07780 74f2226b56c1bb72b21c2ec1e7eeb8db 435 Hamap MF_00118_A Elongation factor Tu [tuf]. 1 430 59.995 T 31-10-2018 IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 Reactome: R-HSA-156842 DFR85_07780 74f2226b56c1bb72b21c2ec1e7eeb8db 435 Gene3D G3DSA:3.40.50.300 1 225 1.8E-80 T 31-10-2018 DFR85_07780 74f2226b56c1bb72b21c2ec1e7eeb8db 435 TIGRFAM TIGR00483 EF-1_alpha: translation elongation factor EF-1, subunit alpha 3 431 6.5E-195 T 31-10-2018 IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 Reactome: R-HSA-156842 DFR85_06100 14d525e9cef078a4f4701fe421d34eee 452 SUPERFAMILY SSF53300 289 433 2.7E-17 T 31-10-2018 IPR036465 von Willebrand factor A-like domain superfamily DFR85_06100 14d525e9cef078a4f4701fe421d34eee 452 Gene3D G3DSA:3.40.50.410 290 452 4.6E-12 T 31-10-2018 IPR036465 von Willebrand factor A-like domain superfamily DFR85_06100 14d525e9cef078a4f4701fe421d34eee 452 SMART SM00327 287 451 7.4E-7 T 31-10-2018 IPR002035 von Willebrand factor, type A DFR85_06100 14d525e9cef078a4f4701fe421d34eee 452 Pfam PF00092 von Willebrand factor type A domain 290 441 1.5E-7 T 31-10-2018 IPR002035 von Willebrand factor, type A DFR85_06085 e1be6caf896783dce9742a4c80ad3476 315 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 57 65 - T 31-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 DFR85_06085 e1be6caf896783dce9742a4c80ad3476 315 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 10 115 8.6E-32 T 31-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 DFR85_06085 e1be6caf896783dce9742a4c80ad3476 315 SUPERFAMILY SSF46548 112 236 1.74E-30 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 DFR85_06085 e1be6caf896783dce9742a4c80ad3476 315 Gene3D G3DSA:3.10.20.30 1 110 2.9E-31 T 31-10-2018 IPR012675 Beta-grasp domain superfamily DFR85_06085 e1be6caf896783dce9742a4c80ad3476 315 Gene3D G3DSA:1.10.1060.10 111 245 1.7E-35 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 DFR85_06085 e1be6caf896783dce9742a4c80ad3476 315 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 12 232 2.0E-64 T 31-10-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 DFR85_06085 e1be6caf896783dce9742a4c80ad3476 315 Pfam PF13183 4Fe-4S dicluster domain 151 222 3.0E-10 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR85_06085 e1be6caf896783dce9742a4c80ad3476 315 SUPERFAMILY SSF54292 8 110 2.49E-25 T 31-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 DFR85_06085 e1be6caf896783dce9742a4c80ad3476 315 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 208 219 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR85_11640 e3d6932ce4e4c5023987e8436fcc7281 198 Pfam PF00175 Oxidoreductase NAD-binding domain 97 147 2.1E-5 T 31-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 DFR85_11640 e3d6932ce4e4c5023987e8436fcc7281 198 SUPERFAMILY SSF52343 75 190 9.56E-15 T 31-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain DFR85_11640 e3d6932ce4e4c5023987e8436fcc7281 198 SUPERFAMILY SSF63380 15 89 8.42E-9 T 31-10-2018 IPR017938 Riboflavin synthase-like beta-barrel DFR85_11640 e3d6932ce4e4c5023987e8436fcc7281 198 PRINTS PR00410 Phenol hydroxylase reductase family signature 25 37 4.2E-6 T 31-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 DFR85_11640 e3d6932ce4e4c5023987e8436fcc7281 198 PRINTS PR00410 Phenol hydroxylase reductase family signature 96 115 4.2E-6 T 31-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 DFR85_11640 e3d6932ce4e4c5023987e8436fcc7281 198 PRINTS PR00410 Phenol hydroxylase reductase family signature 40 47 4.2E-6 T 31-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 DFR85_11640 e3d6932ce4e4c5023987e8436fcc7281 198 Gene3D G3DSA:3.40.50.80 85 197 2.5E-11 T 31-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain DFR85_11640 e3d6932ce4e4c5023987e8436fcc7281 198 Gene3D G3DSA:2.40.30.10 1 81 1.2E-10 T 31-10-2018 DFR85_06850 8573b71eb9adca5e3f61362ef395c313 455 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 259 370 1.5E-16 T 31-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DFR85_06850 8573b71eb9adca5e3f61362ef395c313 455 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 91 100 - T 31-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DFR85_06850 8573b71eb9adca5e3f61362ef395c313 455 Gene3D G3DSA:3.40.120.10 255 363 1.9E-64 T 31-10-2018 DFR85_06850 8573b71eb9adca5e3f61362ef395c313 455 SUPERFAMILY SSF55957 361 453 6.28E-21 T 31-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DFR85_06850 8573b71eb9adca5e3f61362ef395c313 455 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 384 449 1.2E-11 T 31-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DFR85_06850 8573b71eb9adca5e3f61362ef395c313 455 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 154 254 1.4E-21 T 31-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DFR85_06850 8573b71eb9adca5e3f61362ef395c313 455 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 206 219 3.4E-14 T 31-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DFR85_06850 8573b71eb9adca5e3f61362ef395c313 455 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 172 191 3.4E-14 T 31-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DFR85_06850 8573b71eb9adca5e3f61362ef395c313 455 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 90 104 3.4E-14 T 31-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DFR85_06850 8573b71eb9adca5e3f61362ef395c313 455 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 234 249 3.4E-14 T 31-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DFR85_06850 8573b71eb9adca5e3f61362ef395c313 455 SUPERFAMILY SSF53738 242 372 3.02E-17 T 31-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DFR85_06850 8573b71eb9adca5e3f61362ef395c313 455 Gene3D G3DSA:3.40.120.10 1 150 7.3E-57 T 31-10-2018 DFR85_06850 8573b71eb9adca5e3f61362ef395c313 455 Gene3D G3DSA:3.30.310.50 371 453 5.8E-25 T 31-10-2018 DFR85_06850 8573b71eb9adca5e3f61362ef395c313 455 SUPERFAMILY SSF53738 3 178 2.24E-44 T 31-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DFR85_06850 8573b71eb9adca5e3f61362ef395c313 455 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 133 4.4E-45 T 31-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DFR85_06850 8573b71eb9adca5e3f61362ef395c313 455 Gene3D G3DSA:3.40.120.10 162 358 1.9E-64 T 31-10-2018 DFR85_06850 8573b71eb9adca5e3f61362ef395c313 455 TIGRFAM TIGR03990 Arch_GlmM: phosphoglucosamine mutase 3 451 5.3E-164 T 31-10-2018 IPR024086 Phosphoglucosamine mutase, archaeal type GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DFR85_06850 8573b71eb9adca5e3f61362ef395c313 455 SUPERFAMILY SSF53738 153 256 7.85E-25 T 31-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 DFR85_14350 345d8793447daa4a6fd18d7e92bd1cc9 132 Gene3D G3DSA:2.102.10.10 6 113 6.4E-24 T 31-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 DFR85_14350 345d8793447daa4a6fd18d7e92bd1cc9 132 Pfam PF00355 Rieske [2Fe-2S] domain 7 84 2.1E-11 T 31-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DFR85_14350 345d8793447daa4a6fd18d7e92bd1cc9 132 SUPERFAMILY SSF50022 7 108 1.83E-22 T 31-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 DFR85_13855 1ea0fc8700e4f9b1f9029eb08998712c 268 Gene3D G3DSA:3.20.20.60 1 268 1.8E-81 T 31-10-2018 DFR85_13855 1ea0fc8700e4f9b1f9029eb08998712c 268 PIRSF PIRSF015582 1 267 4.5E-79 T 31-10-2018 IPR011206 Citrate lyase beta subunit-like DFR85_13855 1ea0fc8700e4f9b1f9029eb08998712c 268 SUPERFAMILY SSF51621 2 219 3.42E-50 T 31-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 DFR85_13855 1ea0fc8700e4f9b1f9029eb08998712c 268 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 112 207 3.3E-12 T 31-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 DFR85_13855 1ea0fc8700e4f9b1f9029eb08998712c 268 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 4 95 1.5E-18 T 31-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 DFR85_06540 3886b24fda4c2df2b36ded7f4fa80b49 128 Pfam PF01201 Ribosomal protein S8e 4 125 2.1E-27 T 31-10-2018 IPR022309 Ribosomal protein S8e/ribosomal biogenesis NSA2 DFR85_06540 3886b24fda4c2df2b36ded7f4fa80b49 128 Hamap MF_00029 30S ribosomal protein S8e [rps8e]. 2 127 29.789 T 31-10-2018 IPR020919 Ribosomal protein S8e, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_06540 3886b24fda4c2df2b36ded7f4fa80b49 128 ProSitePatterns PS01193 Ribosomal protein S8e signature. 10 29 - T 31-10-2018 IPR018283 Ribosomal protein S8e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_06540 3886b24fda4c2df2b36ded7f4fa80b49 128 Gene3D G3DSA:2.40.10.310 58 128 2.6E-30 T 31-10-2018 DFR85_06540 3886b24fda4c2df2b36ded7f4fa80b49 128 TIGRFAM TIGR00307 eS8: ribosomal protein eS8 1 127 8.3E-36 T 31-10-2018 IPR001047 Ribosomal protein S8e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_00910 7568f409cdca349e147a603e306897b0 332 SMART SM00829 10 330 0.0046 T 31-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DFR85_00910 7568f409cdca349e147a603e306897b0 332 Gene3D G3DSA:3.90.180.10 14 324 4.4E-78 T 31-10-2018 DFR85_00910 7568f409cdca349e147a603e306897b0 332 Pfam PF00107 Zinc-binding dehydrogenase 170 295 5.5E-14 T 31-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DFR85_00910 7568f409cdca349e147a603e306897b0 332 SUPERFAMILY SSF50129 2 157 5.82E-40 T 31-10-2018 IPR011032 GroES-like superfamily DFR85_00910 7568f409cdca349e147a603e306897b0 332 Gene3D G3DSA:3.40.50.720 146 281 4.4E-78 T 31-10-2018 DFR85_00910 7568f409cdca349e147a603e306897b0 332 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 132 4.8E-28 T 31-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DFR85_00910 7568f409cdca349e147a603e306897b0 332 SUPERFAMILY SSF51735 138 301 4.54E-28 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_00910 7568f409cdca349e147a603e306897b0 332 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 31-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 DFR85_02455 00a4e27d0603d1318c60186e85488bcc 158 PIRSF PIRSF000709 3 87 4.5E-5 T 31-10-2018 DFR85_02455 00a4e27d0603d1318c60186e85488bcc 158 SMART SM00855 3 116 1.4E-4 T 31-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 DFR85_02455 00a4e27d0603d1318c60186e85488bcc 158 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 83 1.1E-10 T 31-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 DFR85_02455 00a4e27d0603d1318c60186e85488bcc 158 SUPERFAMILY SSF53254 1 139 3.05E-25 T 31-10-2018 IPR029033 Histidine phosphatase superfamily DFR85_02455 00a4e27d0603d1318c60186e85488bcc 158 TIGRFAM TIGR00249 sixA: phosphohistidine phosphatase SixA 4 126 1.3E-27 T 31-10-2018 IPR004449 Phosphohistidine phosphatase SixA GO:0005737|GO:0006464|GO:0101006 DFR85_02455 00a4e27d0603d1318c60186e85488bcc 158 Gene3D G3DSA:3.40.50.1240 2 158 1.3E-32 T 31-10-2018 IPR029033 Histidine phosphatase superfamily DFR85_05945 5609780eeda0b00e70f4a40b05835fcc 794 SUPERFAMILY SSF81665 1 789 1.01E-78 T 31-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 DFR85_05945 5609780eeda0b00e70f4a40b05835fcc 794 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 310 316 - T 31-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 DFR85_05945 5609780eeda0b00e70f4a40b05835fcc 794 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 82 494 1.2E-59 T 31-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 DFR85_05945 5609780eeda0b00e70f4a40b05835fcc 794 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 509 633 1.8E-29 T 31-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 DFR85_05945 5609780eeda0b00e70f4a40b05835fcc 794 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 548 567 6.1E-35 T 31-10-2018 DFR85_05945 5609780eeda0b00e70f4a40b05835fcc 794 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 571 583 6.1E-35 T 31-10-2018 DFR85_05945 5609780eeda0b00e70f4a40b05835fcc 794 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 308 322 6.1E-35 T 31-10-2018 DFR85_05945 5609780eeda0b00e70f4a40b05835fcc 794 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 159 173 6.1E-35 T 31-10-2018 DFR85_05945 5609780eeda0b00e70f4a40b05835fcc 794 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 470 480 6.1E-35 T 31-10-2018 DFR85_05945 5609780eeda0b00e70f4a40b05835fcc 794 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 448 459 6.1E-35 T 31-10-2018 DFR85_05945 5609780eeda0b00e70f4a40b05835fcc 794 SUPERFAMILY SSF56784 309 634 1.99E-39 T 31-10-2018 IPR036412 HAD-like superfamily DFR85_05945 5609780eeda0b00e70f4a40b05835fcc 794 Pfam PF00690 Cation transporter/ATPase, N-terminus 5 69 1.2E-16 T 31-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 DFR85_05945 5609780eeda0b00e70f4a40b05835fcc 794 Pfam PF00122 E1-E2 ATPase 113 288 1.6E-49 T 31-10-2018 DFR85_05945 5609780eeda0b00e70f4a40b05835fcc 794 SUPERFAMILY SSF81653 112 209 2.09E-30 T 31-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 DFR85_05945 5609780eeda0b00e70f4a40b05835fcc 794 Gene3D G3DSA:1.20.1110.10 190 323 3.2E-13 T 31-10-2018 DFR85_05945 5609780eeda0b00e70f4a40b05835fcc 794 Gene3D G3DSA:3.40.50.1000 449 517 5.8E-7 T 31-10-2018 IPR023214 HAD superfamily DFR85_05945 5609780eeda0b00e70f4a40b05835fcc 794 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 418 436 3.8E-26 T 31-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 DFR85_05945 5609780eeda0b00e70f4a40b05835fcc 794 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 548 564 3.8E-26 T 31-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 DFR85_05945 5609780eeda0b00e70f4a40b05835fcc 794 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 579 604 3.8E-26 T 31-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 DFR85_05945 5609780eeda0b00e70f4a40b05835fcc 794 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 520 536 3.8E-26 T 31-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 DFR85_05945 5609780eeda0b00e70f4a40b05835fcc 794 Pfam PF00702 haloacid dehalogenase-like hydrolase 305 561 9.7E-24 T 31-10-2018 DFR85_05945 5609780eeda0b00e70f4a40b05835fcc 794 Gene3D G3DSA:2.70.150.10 89 189 4.4E-26 T 31-10-2018 DFR85_05945 5609780eeda0b00e70f4a40b05835fcc 794 Gene3D G3DSA:3.40.1110.10 324 448 9.3E-29 T 31-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 DFR85_05945 5609780eeda0b00e70f4a40b05835fcc 794 TIGRFAM TIGR01647 ATPase-IIIA_H: plasma-membrane proton-efflux P-type ATPase 22 753 4.3E-243 T 31-10-2018 IPR006534 P-type ATPase, subfamily IIIA GO:0008553|GO:0016021|GO:0120029 KEGG: 00190+3.6.3.6 DFR85_05945 5609780eeda0b00e70f4a40b05835fcc 794 SMART SM00831 3 75 1.1E-20 T 31-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 DFR85_05945 5609780eeda0b00e70f4a40b05835fcc 794 Gene3D G3DSA:1.20.1110.10 518 789 2.7E-48 T 31-10-2018 DFR85_05945 5609780eeda0b00e70f4a40b05835fcc 794 SUPERFAMILY SSF81660 344 441 5.56E-9 T 31-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 DFR85_01695 87b323b883b2caf7ec432ae540a261d7 350 Pfam PF13353 4Fe-4S single cluster domain 6 118 4.2E-8 T 31-10-2018 DFR85_01695 87b323b883b2caf7ec432ae540a261d7 350 Pfam PF04055 Radical SAM superfamily 6 144 1.2E-11 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR85_01695 87b323b883b2caf7ec432ae540a261d7 350 SUPERFAMILY SSF102114 4 288 1.31E-36 T 31-10-2018 DFR85_01695 87b323b883b2caf7ec432ae540a261d7 350 TIGRFAM TIGR04084 rSAM_AF0577: putative peptide-modifying radical SAM enzyme, AF0577 family 6 350 1.6E-174 T 31-10-2018 IPR023819 Peptide-modifying radical SAM enzyme putative, AF0577 DFR85_01695 87b323b883b2caf7ec432ae540a261d7 350 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 229 295 3.7E-8 T 31-10-2018 IPR023885 4Fe4S-binding SPASM domain DFR85_01695 87b323b883b2caf7ec432ae540a261d7 350 Gene3D G3DSA:3.20.20.70 1 328 2.8E-43 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_05325 52e95192d4da45caa067467a6f678202 320 SUPERFAMILY SSF52402 24 237 1.9E-44 T 31-10-2018 DFR85_05325 52e95192d4da45caa067467a6f678202 320 Gene3D G3DSA:3.40.50.620 1 319 1.3E-73 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR85_05325 52e95192d4da45caa067467a6f678202 320 PIRSF PIRSF004976 1 316 9.3E-90 T 31-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 DFR85_05325 52e95192d4da45caa067467a6f678202 320 Pfam PF01171 PP-loop family 49 228 3.5E-16 T 31-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 DFR85_05325 52e95192d4da45caa067467a6f678202 320 ProSitePatterns PS01263 Uncharacterized protein family UPF0021 signature. 22 59 - T 31-10-2018 IPR020554 Uncharacterised protein family UPF0021, conserved site DFR85_13990 46d2193239117e2bf80015626dc1aed0 747 Gene3D G3DSA:3.30.365.10 148 359 5.7E-63 T 31-10-2018 DFR85_13990 46d2193239117e2bf80015626dc1aed0 747 SUPERFAMILY SSF54665 2 153 3.79E-39 T 31-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily DFR85_13990 46d2193239117e2bf80015626dc1aed0 747 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 150 686 3.5E-158 T 31-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DFR85_13990 46d2193239117e2bf80015626dc1aed0 747 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 18 135 2.5E-26 T 31-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DFR85_13990 46d2193239117e2bf80015626dc1aed0 747 Gene3D G3DSA:3.30.365.10 455 603 9.1E-111 T 31-10-2018 DFR85_13990 46d2193239117e2bf80015626dc1aed0 747 Gene3D G3DSA:3.30.365.10 190 284 5.7E-63 T 31-10-2018 DFR85_13990 46d2193239117e2bf80015626dc1aed0 747 SMART SM01008 18 135 3.7E-40 T 31-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DFR85_13990 46d2193239117e2bf80015626dc1aed0 747 SUPERFAMILY SSF56003 127 746 4.32E-178 T 31-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 DFR85_13990 46d2193239117e2bf80015626dc1aed0 747 Gene3D G3DSA:3.90.1170.50 1 135 1.2E-37 T 31-10-2018 DFR85_13990 46d2193239117e2bf80015626dc1aed0 747 Gene3D G3DSA:3.30.365.10 368 727 9.1E-111 T 31-10-2018 DFR85_09160 16f4795e7f85e0da42d1c32302984395 288 Gene3D G3DSA:1.10.357.140 19 176 8.9E-12 T 31-10-2018 DFR85_09160 16f4795e7f85e0da42d1c32302984395 288 Pfam PF01040 UbiA prenyltransferase family 28 265 3.2E-49 T 31-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 DFR85_09160 16f4795e7f85e0da42d1c32302984395 288 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 12 281 2.2E-82 T 31-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 DFR85_09160 16f4795e7f85e0da42d1c32302984395 288 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 8 284 16.893 T 31-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 DFR85_10300 872bed9bb7a7eda9b08def3cbd2d2f61 403 SUPERFAMILY SSF103473 6 398 3.92E-45 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_10300 872bed9bb7a7eda9b08def3cbd2d2f61 403 Gene3D G3DSA:1.20.1250.20 6 186 3.1E-31 T 31-10-2018 DFR85_10300 872bed9bb7a7eda9b08def3cbd2d2f61 403 Pfam PF07690 Major Facilitator Superfamily 236 395 4.1E-9 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_10300 872bed9bb7a7eda9b08def3cbd2d2f61 403 Pfam PF07690 Major Facilitator Superfamily 15 181 3.0E-29 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_10300 872bed9bb7a7eda9b08def3cbd2d2f61 403 Gene3D G3DSA:1.20.1250.20 229 402 3.0E-10 T 31-10-2018 DFR85_10300 872bed9bb7a7eda9b08def3cbd2d2f61 403 PRINTS PR01036 Tetracycline resistance protein TetB signature 131 155 1.6E-8 T 31-10-2018 DFR85_10300 872bed9bb7a7eda9b08def3cbd2d2f61 403 PRINTS PR01036 Tetracycline resistance protein TetB signature 10 34 1.6E-8 T 31-10-2018 DFR85_10300 872bed9bb7a7eda9b08def3cbd2d2f61 403 PRINTS PR01036 Tetracycline resistance protein TetB signature 210 228 1.6E-8 T 31-10-2018 DFR85_10300 872bed9bb7a7eda9b08def3cbd2d2f61 403 PRINTS PR01036 Tetracycline resistance protein TetB signature 371 390 1.6E-8 T 31-10-2018 DFR85_10300 872bed9bb7a7eda9b08def3cbd2d2f61 403 PRINTS PR01036 Tetracycline resistance protein TetB signature 70 92 1.6E-8 T 31-10-2018 DFR85_08610 ff1452fb0fda9f0d6d1e08f6cc88e645 383 Pfam PF01888 CbiD 28 284 4.7E-83 T 31-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 DFR85_08610 ff1452fb0fda9f0d6d1e08f6cc88e645 383 TIGRFAM TIGR00312 cbiD: cobalamin biosynthesis protein CbiD 34 376 1.3E-83 T 31-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 DFR85_08610 ff1452fb0fda9f0d6d1e08f6cc88e645 383 SUPERFAMILY SSF111342 21 302 4.58E-77 T 31-10-2018 IPR036074 CbiD superfamily GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 DFR85_08610 ff1452fb0fda9f0d6d1e08f6cc88e645 383 Gene3D G3DSA:3.30.2110.10 29 199 8.4E-46 T 31-10-2018 IPR036074 CbiD superfamily GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 DFR85_08610 ff1452fb0fda9f0d6d1e08f6cc88e645 383 Hamap MF_00787 Cobalt-precorrin-5B C(1)-methyltransferase [cbiD]. 27 375 27.934 T 31-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 DFR85_08610 ff1452fb0fda9f0d6d1e08f6cc88e645 383 PIRSF PIRSF026782 23 382 4.3E-116 T 31-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 DFR85_05185 f1c2cc4573f4a808c74f1991e0b65545 754 SUPERFAMILY SSF56784 473 752 1.22E-41 T 31-10-2018 IPR036412 HAD-like superfamily DFR85_05185 f1c2cc4573f4a808c74f1991e0b65545 754 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 250 740 5.8E-85 T 31-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 DFR85_05185 f1c2cc4573f4a808c74f1991e0b65545 754 Gene3D G3DSA:3.40.1110.10 485 584 3.9E-68 T 31-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 DFR85_05185 f1c2cc4573f4a808c74f1991e0b65545 754 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 217 752 3.4E-155 T 31-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 DFR85_05185 f1c2cc4573f4a808c74f1991e0b65545 754 SUPERFAMILY SSF81665 155 744 1.44E-17 T 31-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 DFR85_05185 f1c2cc4573f4a808c74f1991e0b65545 754 Gene3D G3DSA:3.40.50.1000 455 684 3.9E-68 T 31-10-2018 IPR023214 HAD superfamily DFR85_05185 f1c2cc4573f4a808c74f1991e0b65545 754 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 199 752 1.3E-155 T 31-10-2018 DFR85_05185 f1c2cc4573f4a808c74f1991e0b65545 754 Pfam PF00122 E1-E2 ATPase 275 455 6.2E-55 T 31-10-2018 DFR85_05185 f1c2cc4573f4a808c74f1991e0b65545 754 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 475 489 8.4E-19 T 31-10-2018 DFR85_05185 f1c2cc4573f4a808c74f1991e0b65545 754 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 673 685 8.4E-19 T 31-10-2018 DFR85_05185 f1c2cc4573f4a808c74f1991e0b65545 754 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 324 338 8.4E-19 T 31-10-2018 DFR85_05185 f1c2cc4573f4a808c74f1991e0b65545 754 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 650 669 8.4E-19 T 31-10-2018 DFR85_05185 f1c2cc4573f4a808c74f1991e0b65545 754 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 477 483 - T 31-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 DFR85_05185 f1c2cc4573f4a808c74f1991e0b65545 754 Gene3D G3DSA:2.70.150.20 269 379 5.4E-30 T 31-10-2018 DFR85_05185 f1c2cc4573f4a808c74f1991e0b65545 754 SUPERFAMILY SSF81653 278 373 4.18E-25 T 31-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 DFR85_05185 f1c2cc4573f4a808c74f1991e0b65545 754 SUPERFAMILY SSF55008 15 75 1.19E-16 T 31-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 DFR85_05185 f1c2cc4573f4a808c74f1991e0b65545 754 Pfam PF00403 Heavy-metal-associated domain 15 73 4.9E-16 T 31-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 DFR85_05185 f1c2cc4573f4a808c74f1991e0b65545 754 ProSitePatterns PS01047 Heavy-metal-associated domain. 17 46 - T 31-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 DFR85_05185 f1c2cc4573f4a808c74f1991e0b65545 754 Pfam PF00702 haloacid dehalogenase-like hydrolase 472 664 6.5E-36 T 31-10-2018 DFR85_05185 f1c2cc4573f4a808c74f1991e0b65545 754 PRINTS PR00943 Copper-transporting ATPase signature 119 139 7.9E-7 T 31-10-2018 DFR85_05185 f1c2cc4573f4a808c74f1991e0b65545 754 PRINTS PR00943 Copper-transporting ATPase signature 628 645 7.9E-7 T 31-10-2018 DFR85_05185 f1c2cc4573f4a808c74f1991e0b65545 754 PRINTS PR00943 Copper-transporting ATPase signature 397 411 7.9E-7 T 31-10-2018 DFR85_05185 f1c2cc4573f4a808c74f1991e0b65545 754 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 246 729 1.3E-115 T 31-10-2018 DFR85_05185 f1c2cc4573f4a808c74f1991e0b65545 754 Gene3D G3DSA:3.30.70.100 12 78 8.1E-18 T 31-10-2018 DFR85_10635 05735218bc46cfe77789ab474dd6a480 348 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 159 328 2.2E-26 T 31-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 DFR85_10635 05735218bc46cfe77789ab474dd6a480 348 Gene3D G3DSA:3.30.360.10 150 325 1.1E-126 T 31-10-2018 DFR85_10635 05735218bc46cfe77789ab474dd6a480 348 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 5 129 4.1E-32 T 31-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 DFR85_10635 05735218bc46cfe77789ab474dd6a480 348 TIGRFAM TIGR00978 asd_EA: aspartate-semialdehyde dehydrogenase 4 343 1.2E-140 T 31-10-2018 IPR005676 Aspartate-semialdehyde dehydrogenase, peptidoglycan lacking GO:0050661|GO:0055114 DFR85_10635 05735218bc46cfe77789ab474dd6a480 348 SUPERFAMILY SSF51735 4 177 4.01E-42 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_10635 05735218bc46cfe77789ab474dd6a480 348 Gene3D G3DSA:3.40.50.720 5 340 1.1E-126 T 31-10-2018 DFR85_10635 05735218bc46cfe77789ab474dd6a480 348 SUPERFAMILY SSF55347 148 330 4.17E-36 T 31-10-2018 DFR85_10635 05735218bc46cfe77789ab474dd6a480 348 SMART SM00859 5 131 6.9E-34 T 31-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 DFR85_10635 05735218bc46cfe77789ab474dd6a480 348 PIRSF PIRSF000148 3 348 4.9E-87 T 31-10-2018 DFR85_07630 0be70db80621ac9a3196dc6fc7df1644 269 Pfam PF00800 Prephenate dehydratase 13 183 6.3E-44 T 31-10-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 DFR85_07630 0be70db80621ac9a3196dc6fc7df1644 269 SUPERFAMILY SSF55021 185 266 1.37E-16 T 31-10-2018 DFR85_07630 0be70db80621ac9a3196dc6fc7df1644 269 SUPERFAMILY SSF53850 13 185 1.3E-40 T 31-10-2018 DFR85_07630 0be70db80621ac9a3196dc6fc7df1644 269 Gene3D G3DSA:3.30.70.260 183 268 6.1E-18 T 31-10-2018 DFR85_07630 0be70db80621ac9a3196dc6fc7df1644 269 Gene3D G3DSA:3.40.190.10 91 172 2.6E-40 T 31-10-2018 DFR85_07630 0be70db80621ac9a3196dc6fc7df1644 269 Gene3D G3DSA:3.40.190.10 15 181 2.6E-40 T 31-10-2018 DFR85_07225 1de4b6787c206a7c46fdc1e08dc274f8 216 Hamap MF_00359 30S ribosomal protein S3Ae [rps3ae]. 8 198 33.806 T 31-10-2018 IPR030838 30S ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 DFR85_07225 1de4b6787c206a7c46fdc1e08dc274f8 216 SMART SM01397 8 198 1.7E-89 T 31-10-2018 IPR001593 Ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07225 1de4b6787c206a7c46fdc1e08dc274f8 216 Pfam PF01015 Ribosomal S3Ae family 10 195 1.3E-62 T 31-10-2018 IPR001593 Ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_09275 31fadd17dbc47ddef63eeddc91fce607 702 SUPERFAMILY SSF56042 190 397 1.29E-37 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily DFR85_09275 31fadd17dbc47ddef63eeddc91fce607 702 Gene3D G3DSA:3.90.650.10 16 345 1.4E-113 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily DFR85_09275 31fadd17dbc47ddef63eeddc91fce607 702 Gene3D G3DSA:3.30.1330.10 30 181 1.4E-113 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily DFR85_09275 31fadd17dbc47ddef63eeddc91fce607 702 Gene3D G3DSA:3.30.1330.10 359 534 7.5E-39 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily DFR85_09275 31fadd17dbc47ddef63eeddc91fce607 702 SUPERFAMILY SSF55326 5 182 5.08E-46 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily DFR85_09275 31fadd17dbc47ddef63eeddc91fce607 702 Gene3D G3DSA:3.90.650.10 541 701 6.6E-12 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily DFR85_09275 31fadd17dbc47ddef63eeddc91fce607 702 SUPERFAMILY SSF55326 372 532 9.16E-35 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily DFR85_09275 31fadd17dbc47ddef63eeddc91fce607 702 Pfam PF02769 AIR synthase related protein, C-terminal domain 586 677 3.3E-7 T 31-10-2018 IPR010918 PurM-like, C-terminal domain DFR85_09275 31fadd17dbc47ddef63eeddc91fce607 702 Pfam PF02769 AIR synthase related protein, C-terminal domain 199 335 7.4E-27 T 31-10-2018 IPR010918 PurM-like, C-terminal domain DFR85_09275 31fadd17dbc47ddef63eeddc91fce607 702 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 702 191.827 T 31-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 DFR85_09275 31fadd17dbc47ddef63eeddc91fce607 702 Pfam PF00586 AIR synthase related protein, N-terminal domain 427 530 4.6E-12 T 31-10-2018 IPR016188 PurM-like, N-terminal domain DFR85_09275 31fadd17dbc47ddef63eeddc91fce607 702 Pfam PF00586 AIR synthase related protein, N-terminal domain 72 177 2.0E-21 T 31-10-2018 IPR016188 PurM-like, N-terminal domain DFR85_09275 31fadd17dbc47ddef63eeddc91fce607 702 SUPERFAMILY SSF56042 544 698 2.09E-16 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily DFR85_09275 31fadd17dbc47ddef63eeddc91fce607 702 PIRSF PIRSF001587 1 702 1.3E-209 T 31-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 DFR85_09275 31fadd17dbc47ddef63eeddc91fce607 702 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 4 697 4.0E-245 T 31-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 DFR85_00860 978d1b6c132a45ad21d31ef03337d019 277 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 5 166 2.4E-43 T 31-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 DFR85_00860 978d1b6c132a45ad21d31ef03337d019 277 SMART SM01092 174 274 2.4E-25 T 31-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal DFR85_00860 978d1b6c132a45ad21d31ef03337d019 277 SUPERFAMILY SSF55447 174 276 3.4E-26 T 31-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily DFR85_00860 978d1b6c132a45ad21d31ef03337d019 277 Gene3D G3DSA:3.30.390.50 173 277 3.7E-32 T 31-10-2018 DFR85_00860 978d1b6c132a45ad21d31ef03337d019 277 Gene3D G3DSA:3.30.43.10 1 53 5.1E-24 T 31-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 DFR85_00860 978d1b6c132a45ad21d31ef03337d019 277 SUPERFAMILY SSF56176 3 166 6.54E-45 T 31-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 DFR85_00860 978d1b6c132a45ad21d31ef03337d019 277 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 175 273 1.3E-22 T 31-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal DFR85_00860 978d1b6c132a45ad21d31ef03337d019 277 Gene3D G3DSA:3.30.465.10 59 166 8.0E-33 T 31-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 DFR85_13030 e83e365981d8d4be8a5000e890c61953 274 Pfam PF00005 ABC transporter 25 160 1.0E-21 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR85_13030 e83e365981d8d4be8a5000e890c61953 274 Gene3D G3DSA:3.40.50.300 1 256 1.5E-52 T 31-10-2018 DFR85_13030 e83e365981d8d4be8a5000e890c61953 274 SUPERFAMILY SSF52540 2 219 5.43E-50 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_13030 e83e365981d8d4be8a5000e890c61953 274 SMART SM00382 26 205 3.0E-9 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_13030 e83e365981d8d4be8a5000e890c61953 274 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DFR85_10150 853e6a45930a6de9113ddc19ec19c2cb 146 Hamap MF_00308 Prefoldin subunit alpha [pfdA]. 2 141 12.631 T 31-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 DFR85_10150 853e6a45930a6de9113ddc19ec19c2cb 146 SUPERFAMILY SSF46579 11 142 2.41E-14 T 31-10-2018 DFR85_10150 853e6a45930a6de9113ddc19ec19c2cb 146 TIGRFAM TIGR00293 TIGR00293: prefoldin, alpha subunit 12 141 1.1E-18 T 31-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 DFR85_10150 853e6a45930a6de9113ddc19ec19c2cb 146 Pfam PF02996 Prefoldin subunit 22 140 2.2E-15 T 31-10-2018 IPR004127 Prefoldin alpha-like DFR85_10150 853e6a45930a6de9113ddc19ec19c2cb 146 Gene3D G3DSA:1.10.287.370 4 146 8.0E-11 T 31-10-2018 IPR009053 Prefoldin DFR85_02355 ffd553d182b35cd26969e545699f0acd 1305 Pfam PF09286 Pro-kumamolisin, activation domain 40 157 1.4E-21 T 31-10-2018 IPR015366 Peptidase S53, activation domain GO:0008236 Reactome: R-HSA-381038 DFR85_02355 ffd553d182b35cd26969e545699f0acd 1305 SMART SM00944 37 177 2.3E-35 T 31-10-2018 IPR015366 Peptidase S53, activation domain GO:0008236 Reactome: R-HSA-381038 DFR85_02355 ffd553d182b35cd26969e545699f0acd 1305 SUPERFAMILY SSF54897 33 159 4.93E-18 T 31-10-2018 DFR85_02355 ffd553d182b35cd26969e545699f0acd 1305 Gene3D G3DSA:2.60.40.10 1142 1235 3.1E-8 T 31-10-2018 IPR013783 Immunoglobulin-like fold DFR85_02355 ffd553d182b35cd26969e545699f0acd 1305 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 486 496 - T 31-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site DFR85_02355 ffd553d182b35cd26969e545699f0acd 1305 SUPERFAMILY SSF52743 207 564 2.09E-61 T 31-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 DFR85_02355 ffd553d182b35cd26969e545699f0acd 1305 PIRSF PIRSF032623 3 1305 0.0 T 31-10-2018 IPR017001 Peptidase S53, physarolisin II, archaeal-type DFR85_02355 ffd553d182b35cd26969e545699f0acd 1305 Gene3D G3DSA:3.40.50.200 200 568 2.2E-74 T 31-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 DFR85_08850 c587cb0cf3453e0462c89b680e80aaad 404 Pfam PF13662 Toprim domain 167 234 8.7E-10 T 31-10-2018 IPR006171 TOPRIM domain DFR85_08850 c587cb0cf3453e0462c89b680e80aaad 404 SMART SM00493 165 237 8.3E-8 T 31-10-2018 IPR006171 TOPRIM domain DFR85_08850 c587cb0cf3453e0462c89b680e80aaad 404 Gene3D G3DSA:3.40.1360.10 160 258 7.8E-12 T 31-10-2018 DFR85_08850 c587cb0cf3453e0462c89b680e80aaad 404 SUPERFAMILY SSF110455 166 264 2.51E-10 T 31-10-2018 DFR85_08850 c587cb0cf3453e0462c89b680e80aaad 404 Hamap MF_00007 DNA primase DnaG [dnaG]. 1 399 31.565 T 31-10-2018 IPR020607 DNA primase DnaG, archaea GO:0000178|GO:0003896|GO:0008143 DFR85_07115 462ee3e43941c61e048db82bd8b8e729 1047 Gene3D G3DSA:3.40.50.620 14 622 6.2E-218 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR85_07115 462ee3e43941c61e048db82bd8b8e729 1047 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 50 60 - T 31-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR85_07115 462ee3e43941c61e048db82bd8b8e729 1047 SUPERFAMILY SSF50677 201 396 8.27E-51 T 31-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 DFR85_07115 462ee3e43941c61e048db82bd8b8e729 1047 Gene3D G3DSA:1.10.730.10 640 823 4.1E-35 T 31-10-2018 DFR85_07115 462ee3e43941c61e048db82bd8b8e729 1047 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 2 1042 12.611 T 31-10-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 DFR85_07115 462ee3e43941c61e048db82bd8b8e729 1047 Gene3D G3DSA:3.90.740.10 198 400 6.2E-218 T 31-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 DFR85_07115 462ee3e43941c61e048db82bd8b8e729 1047 Pfam PF08264 Anticodon-binding domain of tRNA 683 830 1.3E-26 T 31-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 DFR85_07115 462ee3e43941c61e048db82bd8b8e729 1047 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 555 564 4.3E-27 T 31-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 DFR85_07115 462ee3e43941c61e048db82bd8b8e729 1047 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 394 409 4.3E-27 T 31-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 DFR85_07115 462ee3e43941c61e048db82bd8b8e729 1047 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 41 52 4.3E-27 T 31-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 DFR85_07115 462ee3e43941c61e048db82bd8b8e729 1047 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 222 245 4.3E-27 T 31-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 DFR85_07115 462ee3e43941c61e048db82bd8b8e729 1047 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 517 530 4.3E-27 T 31-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 DFR85_07115 462ee3e43941c61e048db82bd8b8e729 1047 SUPERFAMILY SSF52374 4 640 7.41E-124 T 31-10-2018 DFR85_07115 462ee3e43941c61e048db82bd8b8e729 1047 SUPERFAMILY SSF47323 649 869 1.57E-44 T 31-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR85_07115 462ee3e43941c61e048db82bd8b8e729 1047 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 17 634 9.1E-178 T 31-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR85_07115 462ee3e43941c61e048db82bd8b8e729 1047 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 5 843 9.1E-275 T 31-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 DFR85_07150 4a15d8e94ee748c732d7ecafdd5e0530 128 TIGRFAM TIGR02338 gimC_beta: prefoldin, beta subunit 5 113 7.4E-36 T 31-10-2018 IPR012713 Prefoldin subunit beta GO:0006457|GO:0016272|GO:0051082 DFR85_07150 4a15d8e94ee748c732d7ecafdd5e0530 128 Pfam PF01920 Prefoldin subunit 10 114 1.6E-22 T 31-10-2018 IPR002777 Prefoldin beta-like GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 DFR85_07150 4a15d8e94ee748c732d7ecafdd5e0530 128 Hamap MF_00307 Prefoldin subunit beta [pfdB]. 1 127 44.529 T 31-10-2018 IPR012713 Prefoldin subunit beta GO:0006457|GO:0016272|GO:0051082 DFR85_07150 4a15d8e94ee748c732d7ecafdd5e0530 128 SUPERFAMILY SSF46579 8 113 9.16E-23 T 31-10-2018 DFR85_07150 4a15d8e94ee748c732d7ecafdd5e0530 128 Gene3D G3DSA:1.10.287.370 2 116 3.3E-31 T 31-10-2018 IPR009053 Prefoldin DFR85_15025 6d0d2f524831e208aac945e062fdc8f0 266 Gene3D G3DSA:3.40.50.300 1 216 5.1E-49 T 31-10-2018 DFR85_15025 6d0d2f524831e208aac945e062fdc8f0 266 SMART SM00382 26 189 1.8E-8 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_15025 6d0d2f524831e208aac945e062fdc8f0 266 ProSitePatterns PS00211 ABC transporters family signature. 114 128 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DFR85_15025 6d0d2f524831e208aac945e062fdc8f0 266 SUPERFAMILY SSF52540 4 200 2.24E-47 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_15025 6d0d2f524831e208aac945e062fdc8f0 266 Pfam PF00005 ABC transporter 17 141 1.2E-24 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR85_07535 a006de77c2b1eea42bdd65b4a6fcc5a1 252 SUPERFAMILY SSF51395 16 242 2.31E-39 T 31-10-2018 DFR85_07535 a006de77c2b1eea42bdd65b4a6fcc5a1 252 Gene3D G3DSA:3.20.20.390 2 250 3.1E-80 T 31-10-2018 IPR038597 GGGP/HepGP synthase superfamily DFR85_07535 a006de77c2b1eea42bdd65b4a6fcc5a1 252 Hamap MF_00112 Geranylgeranylglyceryl phosphate synthase [pcrB]. 16 248 32.765 T 31-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 DFR85_07535 a006de77c2b1eea42bdd65b4a6fcc5a1 252 TIGRFAM TIGR01768 GGGP-family: geranylgeranylglyceryl phosphate synthase family protein 21 243 7.2E-81 T 31-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 DFR85_07535 a006de77c2b1eea42bdd65b4a6fcc5a1 252 TIGRFAM TIGR01769 GGGP: phosphoglycerol geranylgeranyltransferase 22 228 2.7E-82 T 31-10-2018 IPR010946 Geranylgeranylglyceryl phosphate synthase GO:0000287|GO:0005737|GO:0006650|GO:0047294 KEGG: 00564+2.5.1.41|MetaCyc: PWY-6349 DFR85_07535 a006de77c2b1eea42bdd65b4a6fcc5a1 252 Pfam PF01884 PcrB family 18 242 5.7E-50 T 31-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 DFR85_02885 fec2dba2b70f9ec57b76c6db05770af8 213 ProSitePatterns PS00397 Site-specific recombinases active site. 62 70 - T 31-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 DFR85_02885 fec2dba2b70f9ec57b76c6db05770af8 213 SMART SM00857 59 182 5.3E-21 T 31-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 DFR85_02885 fec2dba2b70f9ec57b76c6db05770af8 213 Pfam PF12728 Helix-turn-helix domain 4 54 2.0E-14 T 31-10-2018 DFR85_02885 fec2dba2b70f9ec57b76c6db05770af8 213 SUPERFAMILY SSF53041 58 188 5.36E-24 T 31-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 DFR85_02885 fec2dba2b70f9ec57b76c6db05770af8 213 Gene3D G3DSA:3.40.50.1390 59 156 5.5E-25 T 31-10-2018 DFR85_02885 fec2dba2b70f9ec57b76c6db05770af8 213 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 5 53 3.7E-15 T 31-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 DFR85_02885 fec2dba2b70f9ec57b76c6db05770af8 213 Gene3D G3DSA:1.10.1660.10 5 58 7.3E-7 T 31-10-2018 DFR85_02885 fec2dba2b70f9ec57b76c6db05770af8 213 Pfam PF00239 Resolvase, N terminal domain 59 188 1.2E-20 T 31-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 DFR85_02885 fec2dba2b70f9ec57b76c6db05770af8 213 SUPERFAMILY SSF46955 3 54 1.52E-7 T 31-10-2018 IPR009061 Putative DNA-binding domain superfamily DFR85_12605 b2d25d80b1ef24983febd39cf1e66fb9 369 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 72 133 7.0E-9 T 31-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain DFR85_12605 b2d25d80b1ef24983febd39cf1e66fb9 369 Gene3D G3DSA:3.20.20.120 131 367 7.7E-69 T 31-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily DFR85_12605 b2d25d80b1ef24983febd39cf1e66fb9 369 Pfam PF13378 Enolase C-terminal domain-like 154 366 1.9E-46 T 31-10-2018 IPR029065 Enolase C-terminal domain-like DFR85_12605 b2d25d80b1ef24983febd39cf1e66fb9 369 Gene3D G3DSA:3.30.390.10 42 130 8.3E-16 T 31-10-2018 IPR029017 Enolase-like, N-terminal DFR85_12605 b2d25d80b1ef24983febd39cf1e66fb9 369 SMART SM00922 152 254 2.1E-17 T 31-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal DFR85_12605 b2d25d80b1ef24983febd39cf1e66fb9 369 SUPERFAMILY SSF51604 121 366 1.09E-57 T 31-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily DFR85_12605 b2d25d80b1ef24983febd39cf1e66fb9 369 SUPERFAMILY SSF54826 18 136 3.37E-17 T 31-10-2018 DFR85_15500 bd71c45d79000f6d48fc7175476b262e 273 Gene3D G3DSA:3.20.20.140 3 271 1.4E-31 T 31-10-2018 DFR85_15500 bd71c45d79000f6d48fc7175476b262e 273 SUPERFAMILY SSF51556 4 269 1.77E-30 T 31-10-2018 IPR032466 Metal-dependent hydrolase DFR85_15500 bd71c45d79000f6d48fc7175476b262e 273 Pfam PF04909 Amidohydrolase 81 239 9.8E-22 T 31-10-2018 IPR006680 Amidohydrolase-related GO:0016787 DFR85_00720 9f6c8c11d3e9c2b162cea534263cc31b 245 SMART SM00382 32 212 2.0E-11 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_00720 9f6c8c11d3e9c2b162cea534263cc31b 245 Pfam PF00005 ABC transporter 23 166 3.8E-27 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR85_00720 9f6c8c11d3e9c2b162cea534263cc31b 245 Gene3D G3DSA:3.40.50.300 1 245 2.6E-63 T 31-10-2018 DFR85_00720 9f6c8c11d3e9c2b162cea534263cc31b 245 SUPERFAMILY SSF52540 7 225 1.13E-58 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_07785 7388e6958e4381d79441ba8ac562f7a5 102 Gene3D G3DSA:3.30.70.600 2 101 1.0E-29 T 31-10-2018 IPR036838 Ribosomal protein S10 domain superfamily DFR85_07785 7388e6958e4381d79441ba8ac562f7a5 102 Pfam PF00338 Ribosomal protein S10p/S20e 6 99 5.5E-25 T 31-10-2018 IPR027486 Ribosomal protein S10 domain DFR85_07785 7388e6958e4381d79441ba8ac562f7a5 102 TIGRFAM TIGR01046 uS10_euk_arch: ribosomal protein uS10 4 101 4.0E-44 T 31-10-2018 IPR005729 Ribosomal protein S10, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07785 7388e6958e4381d79441ba8ac562f7a5 102 PRINTS PR00971 Ribosomal protein S10 family signature 4 17 3.0E-12 T 31-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07785 7388e6958e4381d79441ba8ac562f7a5 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 3.0E-12 T 31-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07785 7388e6958e4381d79441ba8ac562f7a5 102 PRINTS PR00971 Ribosomal protein S10 family signature 39 54 3.0E-12 T 31-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07785 7388e6958e4381d79441ba8ac562f7a5 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 28 43 - T 31-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07785 7388e6958e4381d79441ba8ac562f7a5 102 SUPERFAMILY SSF54999 4 101 2.09E-27 T 31-10-2018 IPR036838 Ribosomal protein S10 domain superfamily DFR85_07785 7388e6958e4381d79441ba8ac562f7a5 102 SMART SM01403 6 100 3.7E-34 T 31-10-2018 IPR027486 Ribosomal protein S10 domain DFR85_07785 7388e6958e4381d79441ba8ac562f7a5 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 2 101 23.198 T 31-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_02245 1abe91798c5002b764c8a32c2ada41d1 401 Pfam PF07282 Putative transposase DNA-binding domain 305 372 1.3E-23 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR85_02245 1abe91798c5002b764c8a32c2ada41d1 401 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 255 330 3.0E-15 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR85_02245 1abe91798c5002b764c8a32c2ada41d1 401 Pfam PF01385 Probable transposase 181 287 8.3E-20 T 31-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 DFR85_08600 212fb50ac982a90fd13668ff64fd65d8 185 SUPERFAMILY SSF63965 6 182 4.84E-36 T 31-10-2018 IPR036588 Precorrin-8X methylmutase CobH/CbiC superfamily GO:0009236|GO:0016993 DFR85_08600 212fb50ac982a90fd13668ff64fd65d8 185 Pfam PF02570 Precorrin-8X methylmutase 7 181 5.3E-31 T 31-10-2018 IPR003722 Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC GO:0009236|GO:0016993 DFR85_08600 212fb50ac982a90fd13668ff64fd65d8 185 Gene3D G3DSA:3.40.50.10230 2 82 9.2E-10 T 31-10-2018 IPR036588 Precorrin-8X methylmutase CobH/CbiC superfamily GO:0009236|GO:0016993 DFR85_08600 212fb50ac982a90fd13668ff64fd65d8 185 Gene3D G3DSA:3.40.50.10230 83 185 5.0E-23 T 31-10-2018 IPR036588 Precorrin-8X methylmutase CobH/CbiC superfamily GO:0009236|GO:0016993 DFR85_12730 3567398e61a71183c79c08f5179021f9 272 SUPERFAMILY SSF161098 43 263 1.15E-46 T 31-10-2018 IPR035906 MetI-like superfamily DFR85_12730 3567398e61a71183c79c08f5179021f9 272 Gene3D G3DSA:1.10.3720.10 2 266 4.2E-49 T 31-10-2018 IPR035906 MetI-like superfamily DFR85_12730 3567398e61a71183c79c08f5179021f9 272 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 73 262 1.5E-16 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 DFR85_02870 b01b02801a3977c27f9343165fb63e10 476 Pfam PF01979 Amidohydrolase family 63 452 1.2E-23 T 31-10-2018 IPR006680 Amidohydrolase-related GO:0016787 DFR85_02870 b01b02801a3977c27f9343165fb63e10 476 Gene3D G3DSA:3.20.20.140 67 439 6.2E-165 T 31-10-2018 DFR85_02870 b01b02801a3977c27f9343165fb63e10 476 Pfam PF00449 Urease alpha-subunit, N-terminal domain 13 48 8.0E-5 T 31-10-2018 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 DFR85_02870 b01b02801a3977c27f9343165fb63e10 476 Gene3D G3DSA:2.30.40.10 18 471 6.2E-165 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR85_02870 b01b02801a3977c27f9343165fb63e10 476 SUPERFAMILY SSF51556 67 398 1.08E-97 T 31-10-2018 IPR032466 Metal-dependent hydrolase DFR85_02870 b01b02801a3977c27f9343165fb63e10 476 SUPERFAMILY SSF51338 376 470 1.38E-34 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR85_02870 b01b02801a3977c27f9343165fb63e10 476 SUPERFAMILY SSF51338 17 80 2.49E-15 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR85_02870 b01b02801a3977c27f9343165fb63e10 476 TIGRFAM TIGR02033 D-hydantoinase: dihydropyrimidinase 18 468 1.2E-149 T 31-10-2018 IPR011778 Hydantoinase/dihydropyrimidinase GO:0005737 Reactome: R-HSA-399956 DFR85_00945 bf0582c5e30ba89a61572e068f1396c8 476 Gene3D G3DSA:1.20.58.100 375 476 2.1E-30 T 31-10-2018 DFR85_00945 bf0582c5e30ba89a61572e068f1396c8 476 Pfam PF00890 FAD binding domain 4 353 2.6E-74 T 31-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 DFR85_00945 bf0582c5e30ba89a61572e068f1396c8 476 Pfam PF02910 Fumarate reductase flavoprotein C-term 426 472 3.0E-8 T 31-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 DFR85_00945 bf0582c5e30ba89a61572e068f1396c8 476 Gene3D G3DSA:3.50.50.60 4 360 4.7E-142 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_00945 bf0582c5e30ba89a61572e068f1396c8 476 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 2 461 2.4E-137 T 31-10-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 DFR85_00945 bf0582c5e30ba89a61572e068f1396c8 476 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 2 21 5.0E-11 T 31-10-2018 DFR85_00945 bf0582c5e30ba89a61572e068f1396c8 476 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 164 182 5.0E-11 T 31-10-2018 DFR85_00945 bf0582c5e30ba89a61572e068f1396c8 476 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 316 338 5.0E-11 T 31-10-2018 DFR85_00945 bf0582c5e30ba89a61572e068f1396c8 476 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 165 173 3.2E-6 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR85_00945 bf0582c5e30ba89a61572e068f1396c8 476 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 326 344 3.2E-6 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR85_00945 bf0582c5e30ba89a61572e068f1396c8 476 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 60 82 3.2E-6 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR85_00945 bf0582c5e30ba89a61572e068f1396c8 476 SUPERFAMILY SSF46977 394 473 4.45E-20 T 31-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 DFR85_00945 bf0582c5e30ba89a61572e068f1396c8 476 SUPERFAMILY SSF56425 205 313 1.5E-27 T 31-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 DFR85_00945 bf0582c5e30ba89a61572e068f1396c8 476 SUPERFAMILY SSF51905 4 369 2.91E-59 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_00945 bf0582c5e30ba89a61572e068f1396c8 476 Gene3D G3DSA:3.90.700.10 213 308 4.7E-142 T 31-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 DFR85_00945 bf0582c5e30ba89a61572e068f1396c8 476 PIRSF PIRSF000171 1 432 2.8E-29 T 31-10-2018 DFR85_00945 bf0582c5e30ba89a61572e068f1396c8 476 PIRSF PIRSF000171 399 475 3.4E-4 T 31-10-2018 DFR85_12945 d6599105c6b9989ce21913b0237722f0 334 Gene3D G3DSA:3.40.720.10 29 334 4.9E-31 T 31-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 DFR85_12945 d6599105c6b9989ce21913b0237722f0 334 SUPERFAMILY SSF53649 38 333 2.99E-36 T 31-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 DFR85_12945 d6599105c6b9989ce21913b0237722f0 334 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 60 238 8.3E-18 T 31-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 DFR85_12710 96175f7f36b4fc67a6097a67df1dc61b 352 Pfam PF00005 ABC transporter 22 164 2.6E-30 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR85_12710 96175f7f36b4fc67a6097a67df1dc61b 352 Gene3D G3DSA:2.40.50.140 280 336 1.3E-17 T 31-10-2018 DFR85_12710 96175f7f36b4fc67a6097a67df1dc61b 352 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DFR85_12710 96175f7f36b4fc67a6097a67df1dc61b 352 Gene3D G3DSA:2.40.50.100 242 349 1.3E-17 T 31-10-2018 DFR85_12710 96175f7f36b4fc67a6097a67df1dc61b 352 SUPERFAMILY SSF52540 3 245 2.26E-78 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_12710 96175f7f36b4fc67a6097a67df1dc61b 352 Pfam PF08402 TOBE domain 278 343 4.0E-5 T 31-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 DFR85_12710 96175f7f36b4fc67a6097a67df1dc61b 352 SMART SM00382 31 222 6.4E-11 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_12710 96175f7f36b4fc67a6097a67df1dc61b 352 SUPERFAMILY SSF50331 240 351 8.02E-18 T 31-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal DFR85_12710 96175f7f36b4fc67a6097a67df1dc61b 352 Gene3D G3DSA:3.40.50.300 1 241 1.3E-69 T 31-10-2018 DFR85_10155 1cc3db4d5f66f1fbb5c1d03e807b2515 357 Pfam PF02881 SRP54-type protein, helical bundle domain 69 135 3.0E-11 T 31-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 DFR85_10155 1cc3db4d5f66f1fbb5c1d03e807b2515 357 SMART SM00382 161 337 1.3E-7 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_10155 1cc3db4d5f66f1fbb5c1d03e807b2515 357 Gene3D G3DSA:1.20.120.140 39 145 1.2E-22 T 31-10-2018 DFR85_10155 1cc3db4d5f66f1fbb5c1d03e807b2515 357 SMART SM00963 60 143 1.9E-11 T 31-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 DFR85_10155 1cc3db4d5f66f1fbb5c1d03e807b2515 357 Pfam PF00448 SRP54-type protein, GTPase domain 163 356 4.2E-72 T 31-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 DFR85_10155 1cc3db4d5f66f1fbb5c1d03e807b2515 357 SUPERFAMILY SSF47364 70 147 1.23E-13 T 31-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 DFR85_10155 1cc3db4d5f66f1fbb5c1d03e807b2515 357 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 84 356 6.3E-106 T 31-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 DFR85_10155 1cc3db4d5f66f1fbb5c1d03e807b2515 357 SUPERFAMILY SSF52540 158 356 3.03E-50 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_10155 1cc3db4d5f66f1fbb5c1d03e807b2515 357 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 330 343 - T 31-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 DFR85_10155 1cc3db4d5f66f1fbb5c1d03e807b2515 357 Gene3D G3DSA:3.40.50.300 150 357 1.2E-76 T 31-10-2018 DFR85_10155 1cc3db4d5f66f1fbb5c1d03e807b2515 357 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 82 357 57.702 T 31-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 DFR85_10155 1cc3db4d5f66f1fbb5c1d03e807b2515 357 SMART SM00962 162 357 1.6E-100 T 31-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 DFR85_07330 1db00798db4b50b642c0db0395b25f5b 416 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 1 416 48.259 T 31-10-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508|Reactome: R-HSA-5578997 DFR85_07330 1db00798db4b50b642c0db0395b25f5b 416 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 205 222 - T 31-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 DFR85_07330 1db00798db4b50b642c0db0395b25f5b 416 PIRSF PIRSF001109 1 416 8.8E-186 T 31-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 DFR85_07330 1db00798db4b50b642c0db0395b25f5b 416 Gene3D G3DSA:3.40.50.1480 5 405 1.1E-170 T 31-10-2018 DFR85_07330 1db00798db4b50b642c0db0395b25f5b 416 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 142 410 1.0E-25 T 31-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 DFR85_07330 1db00798db4b50b642c0db0395b25f5b 416 SMART SM00996 2 415 9.1E-151 T 31-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 DFR85_07330 1db00798db4b50b642c0db0395b25f5b 416 SUPERFAMILY SSF52283 2 416 5.67E-92 T 31-10-2018 DFR85_07330 1db00798db4b50b642c0db0395b25f5b 416 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 74 88 - T 31-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 DFR85_07330 1db00798db4b50b642c0db0395b25f5b 416 Gene3D G3DSA:3.40.50.720 185 344 1.1E-170 T 31-10-2018 DFR85_07330 1db00798db4b50b642c0db0395b25f5b 416 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 2 138 4.4E-41 T 31-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 DFR85_07330 1db00798db4b50b642c0db0395b25f5b 416 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 3 416 4.1E-192 T 31-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 DFR85_07330 1db00798db4b50b642c0db0395b25f5b 416 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 185 343 1.8E-56 T 31-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 DFR85_07330 1db00798db4b50b642c0db0395b25f5b 416 SUPERFAMILY SSF51735 183 345 3.06E-67 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_07330 1db00798db4b50b642c0db0395b25f5b 416 SMART SM00997 183 344 3.1E-106 T 31-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 DFR85_02500 106c9ac1de058e1982c386c5b3774fb1 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 9.0E-8 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR85_02500 106c9ac1de058e1982c386c5b3774fb1 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 9.0E-8 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR85_02500 106c9ac1de058e1982c386c5b3774fb1 160 SMART SM00344 3 111 1.3E-21 T 31-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 DFR85_02500 106c9ac1de058e1982c386c5b3774fb1 160 Pfam PF01037 Lrp/AsnC ligand binding domain 71 141 6.2E-11 T 31-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DFR85_02500 106c9ac1de058e1982c386c5b3774fb1 160 SUPERFAMILY SSF54909 69 148 1.47E-11 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel DFR85_02500 106c9ac1de058e1982c386c5b3774fb1 160 Pfam PF13412 Winged helix-turn-helix DNA-binding 3 50 9.8E-11 T 31-10-2018 DFR85_02500 106c9ac1de058e1982c386c5b3774fb1 160 SUPERFAMILY SSF46785 2 60 1.26E-13 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_02500 106c9ac1de058e1982c386c5b3774fb1 160 Gene3D G3DSA:3.30.70.920 55 152 1.4E-19 T 31-10-2018 DFR85_02500 106c9ac1de058e1982c386c5b3774fb1 160 Gene3D G3DSA:1.10.10.10 3 54 1.3E-18 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_07360 7f5c3a2841be67ec05cea17f89ecbdf0 170 ProDom PD016584 UPF0106 MK0803 MM0086 METAL MA3241 UNCHARACTERIZED DOMAIN TA0931 APE2006 ST0333 50 169 2.0E-40 T 31-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 DFR85_07360 7f5c3a2841be67ec05cea17f89ecbdf0 170 Hamap MF_00077 tRNA (cytidine(56)-2'-O)-methyltransferase. 1 170 38.095 T 31-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 DFR85_07360 7f5c3a2841be67ec05cea17f89ecbdf0 170 PIRSF PIRSF016123 1 170 4.1E-75 T 31-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 DFR85_07360 7f5c3a2841be67ec05cea17f89ecbdf0 170 SUPERFAMILY SSF75217 1 168 1.86E-65 T 31-10-2018 IPR029028 Alpha/beta knot methyltransferases DFR85_07360 7f5c3a2841be67ec05cea17f89ecbdf0 170 Pfam PF01994 tRNA ribose 2'-O-methyltransferase, aTrm56 50 168 2.8E-46 T 31-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 DFR85_07360 7f5c3a2841be67ec05cea17f89ecbdf0 170 Gene3D G3DSA:3.40.1280.10 1 170 4.6E-67 T 31-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal DFR85_01950 296267ab53acc42c23b1e833d1279eee 618 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 284 295 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR85_01950 296267ab53acc42c23b1e833d1279eee 618 SUPERFAMILY SSF54862 279 342 9.21E-12 T 31-10-2018 DFR85_01950 296267ab53acc42c23b1e833d1279eee 618 Gene3D G3DSA:3.30.70.20 269 340 3.9E-9 T 31-10-2018 DFR85_01950 296267ab53acc42c23b1e833d1279eee 618 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 325 336 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR85_08215 222c4c342f7ec40017072c3fc5e37c09 232 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 185 227 4.4E-11 T 31-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 DFR85_08215 222c4c342f7ec40017072c3fc5e37c09 232 SMART SM00863 184 227 6.6E-13 T 31-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 DFR85_08215 222c4c342f7ec40017072c3fc5e37c09 232 Gene3D G3DSA:2.40.30.130 1 85 9.0E-26 T 31-10-2018 DFR85_08215 222c4c342f7ec40017072c3fc5e37c09 232 SUPERFAMILY SSF55186 89 230 4.45E-37 T 31-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 DFR85_08215 222c4c342f7ec40017072c3fc5e37c09 232 Gene3D G3DSA:3.30.980.10 86 232 8.5E-33 T 31-10-2018 DFR85_08215 222c4c342f7ec40017072c3fc5e37c09 232 Pfam PF01411 tRNA synthetases class II (A) 13 89 4.3E-14 T 31-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 DFR85_08215 222c4c342f7ec40017072c3fc5e37c09 232 SUPERFAMILY SSF50447 2 84 1.52E-14 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily DFR85_02115 53014237f5dc8b3a158fdd5092504d95 440 Pfam PF00202 Aminotransferase class-III 24 432 3.4E-96 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DFR85_02115 53014237f5dc8b3a158fdd5092504d95 440 SUPERFAMILY SSF53383 17 434 1.58E-110 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase DFR85_02115 53014237f5dc8b3a158fdd5092504d95 440 PIRSF PIRSF000521 24 130 8.8E-11 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DFR85_02115 53014237f5dc8b3a158fdd5092504d95 440 PIRSF PIRSF000521 120 435 2.0E-27 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DFR85_02115 53014237f5dc8b3a158fdd5092504d95 440 Gene3D G3DSA:3.40.640.10 59 323 6.4E-149 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR85_02115 53014237f5dc8b3a158fdd5092504d95 440 Gene3D G3DSA:3.90.1150.10 11 430 6.4E-149 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 DFR85_08420 2db8206d73845c22d5b1588f4da8c32e 288 PRINTS PR00146 Dihydrodipicolinate synthase signature 68 86 8.0E-15 T 31-10-2018 IPR002220 DapA-like GO:0016829 DFR85_08420 2db8206d73845c22d5b1588f4da8c32e 288 PRINTS PR00146 Dihydrodipicolinate synthase signature 124 141 8.0E-15 T 31-10-2018 IPR002220 DapA-like GO:0016829 DFR85_08420 2db8206d73845c22d5b1588f4da8c32e 288 PRINTS PR00146 Dihydrodipicolinate synthase signature 100 116 8.0E-15 T 31-10-2018 IPR002220 DapA-like GO:0016829 DFR85_08420 2db8206d73845c22d5b1588f4da8c32e 288 PRINTS PR00146 Dihydrodipicolinate synthase signature 34 55 8.0E-15 T 31-10-2018 IPR002220 DapA-like GO:0016829 DFR85_08420 2db8206d73845c22d5b1588f4da8c32e 288 SMART SM01130 1 287 4.4E-65 T 31-10-2018 IPR002220 DapA-like GO:0016829 DFR85_08420 2db8206d73845c22d5b1588f4da8c32e 288 Pfam PF00701 Dihydrodipicolinate synthetase family 2 271 5.1E-59 T 31-10-2018 IPR002220 DapA-like GO:0016829 DFR85_08420 2db8206d73845c22d5b1588f4da8c32e 288 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 129 159 - T 31-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 DFR85_08420 2db8206d73845c22d5b1588f4da8c32e 288 Gene3D G3DSA:3.20.20.70 1 285 1.1E-70 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_08420 2db8206d73845c22d5b1588f4da8c32e 288 SUPERFAMILY SSF51569 2 271 3.98E-67 T 31-10-2018 DFR85_08420 2db8206d73845c22d5b1588f4da8c32e 288 PIRSF PIRSF001365 1 283 8.7E-63 T 31-10-2018 IPR002220 DapA-like GO:0016829 DFR85_07605 dbd81360534a58f99d1834e7d6216ebf 335 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 63 334 7.4E-89 T 31-10-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 DFR85_07605 dbd81360534a58f99d1834e7d6216ebf 335 SUPERFAMILY SSF53335 25 335 1.71E-68 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR85_07605 dbd81360534a58f99d1834e7d6216ebf 335 Pfam PF01189 16S rRNA methyltransferase RsmB/F 130 333 1.9E-55 T 31-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 DFR85_07605 dbd81360534a58f99d1834e7d6216ebf 335 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 37 126 1.0E-17 T 31-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 DFR85_07605 dbd81360534a58f99d1834e7d6216ebf 335 Gene3D G3DSA:3.30.70.3130 17 125 5.4E-32 T 31-10-2018 DFR85_07605 dbd81360534a58f99d1834e7d6216ebf 335 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 317 334 3.5E-27 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase DFR85_07605 dbd81360534a58f99d1834e7d6216ebf 335 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 257 273 3.5E-27 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase DFR85_07605 dbd81360534a58f99d1834e7d6216ebf 335 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 112 126 3.5E-27 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase DFR85_07605 dbd81360534a58f99d1834e7d6216ebf 335 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 207 219 3.5E-27 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase DFR85_07605 dbd81360534a58f99d1834e7d6216ebf 335 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 141 151 3.5E-27 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase DFR85_07605 dbd81360534a58f99d1834e7d6216ebf 335 Gene3D G3DSA:3.40.50.150 128 335 6.7E-67 T 31-10-2018 DFR85_09670 95e14d213d0826fa06a266327fd37c87 1139 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 562 603 8.5E-7 T 31-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_09670 95e14d213d0826fa06a266327fd37c87 1139 Pfam PF00361 Proton-conducting membrane transporter 120 411 6.8E-46 T 31-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_09670 95e14d213d0826fa06a266327fd37c87 1139 Pfam PF00361 Proton-conducting membrane transporter 617 929 5.4E-31 T 31-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_09670 95e14d213d0826fa06a266327fd37c87 1139 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 756 782 4.6E-18 T 31-10-2018 DFR85_09670 95e14d213d0826fa06a266327fd37c87 1139 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 734 755 4.6E-18 T 31-10-2018 DFR85_09670 95e14d213d0826fa06a266327fd37c87 1139 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 566 591 4.6E-18 T 31-10-2018 DFR85_04120 e3698257ab6b12838c26ac75272e1f89 651 Gene3D G3DSA:3.10.105.10 320 558 1.6E-29 T 31-10-2018 DFR85_04120 e3698257ab6b12838c26ac75272e1f89 651 SUPERFAMILY SSF53850 35 582 4.71E-49 T 31-10-2018 DFR85_04120 e3698257ab6b12838c26ac75272e1f89 651 Gene3D G3DSA:3.40.190.10 24 300 4.6E-20 T 31-10-2018 DFR85_04120 e3698257ab6b12838c26ac75272e1f89 651 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 94 495 1.7E-39 T 31-10-2018 IPR000914 Solute-binding protein family 5 domain DFR85_14300 b8159c0a001dd6b453e5ae8571aabc54 1154 Pfam PF00361 Proton-conducting membrane transporter 658 931 3.8E-28 T 31-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_14300 b8159c0a001dd6b453e5ae8571aabc54 1154 Pfam PF00361 Proton-conducting membrane transporter 116 404 5.8E-35 T 31-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_14300 b8159c0a001dd6b453e5ae8571aabc54 1154 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 556 581 3.4E-19 T 31-10-2018 DFR85_14300 b8159c0a001dd6b453e5ae8571aabc54 1154 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 725 746 3.4E-19 T 31-10-2018 DFR85_14300 b8159c0a001dd6b453e5ae8571aabc54 1154 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 747 773 3.4E-19 T 31-10-2018 DFR85_14300 b8159c0a001dd6b453e5ae8571aabc54 1154 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 934 953 3.4E-19 T 31-10-2018 DFR85_07370 36b012c9fd4aae9f4c478447fe9cf481 163 SMART SM00530 78 133 3.3E-7 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DFR85_07370 36b012c9fd4aae9f4c478447fe9cf481 163 SUPERFAMILY SSF47413 74 138 3.66E-12 T 31-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 DFR85_07370 36b012c9fd4aae9f4c478447fe9cf481 163 Pfam PF01381 Helix-turn-helix 79 129 2.7E-8 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DFR85_07370 36b012c9fd4aae9f4c478447fe9cf481 163 Gene3D G3DSA:1.10.260.40 66 163 2.8E-19 T 31-10-2018 DFR85_07370 36b012c9fd4aae9f4c478447fe9cf481 163 TIGRFAM TIGR00270 TIGR00270: TIGR00270 family protein 8 159 5.2E-31 T 31-10-2018 IPR004451 Conserved hypothetical protein CHP00270 DFR85_02440 4ea1eda206e6616f8370a5e66e9d0e60 385 SUPERFAMILY SSF52922 256 379 1.43E-29 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 DFR85_02440 4ea1eda206e6616f8370a5e66e9d0e60 385 Gene3D G3DSA:3.40.50.920 256 384 1.7E-37 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 DFR85_02440 4ea1eda206e6616f8370a5e66e9d0e60 385 SUPERFAMILY SSF52518 7 252 1.96E-65 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR85_02440 4ea1eda206e6616f8370a5e66e9d0e60 385 Gene3D G3DSA:3.40.50.970 5 254 1.4E-96 T 31-10-2018 DFR85_02440 4ea1eda206e6616f8370a5e66e9d0e60 385 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 265 366 5.2E-31 T 31-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II DFR85_02440 4ea1eda206e6616f8370a5e66e9d0e60 385 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 20 242 1.2E-72 T 31-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 DFR85_03805 c7cef6511f755b534639d95dec025b6d 103 Gene3D G3DSA:2.40.50.970 1 76 2.2E-17 T 31-10-2018 IPR037254 HupF/HypC superfamily DFR85_03805 c7cef6511f755b534639d95dec025b6d 103 Pfam PF01455 HupF/HypC family 1 64 8.0E-16 T 31-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC DFR85_03805 c7cef6511f755b534639d95dec025b6d 103 SUPERFAMILY SSF159127 1 75 5.89E-16 T 31-10-2018 IPR037254 HupF/HypC superfamily DFR85_10105 8701cb7349cd79ee1899af6860d0cbc5 329 Gene3D G3DSA:3.20.70.20 56 329 3.7E-40 T 31-10-2018 DFR85_10105 8701cb7349cd79ee1899af6860d0cbc5 329 Pfam PF05167 Uncharacterised ACR (DUF711) 150 313 4.7E-26 T 31-10-2018 IPR007841 Uncharacterised protein family UPF0210 DFR85_10105 8701cb7349cd79ee1899af6860d0cbc5 329 SUPERFAMILY SSF51998 1 328 3.57E-58 T 31-10-2018 DFR85_06045 1cb21733da7722534092903c4bb0f36c 270 Pfam PF01112 Asparaginase 6 121 8.2E-28 T 31-10-2018 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 DFR85_06045 1cb21733da7722534092903c4bb0f36c 270 Pfam PF01112 Asparaginase 129 261 1.4E-38 T 31-10-2018 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 DFR85_06045 1cb21733da7722534092903c4bb0f36c 270 SUPERFAMILY SSF56235 5 265 9.52E-68 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR85_06045 1cb21733da7722534092903c4bb0f36c 270 Gene3D G3DSA:3.60.20.30 136 269 2.0E-36 T 31-10-2018 DFR85_03500 0f6a5e5a6d66eb68a5bd49dcaacacb72 223 Gene3D G3DSA:3.40.50.150 15 223 3.6E-25 T 31-10-2018 DFR85_03500 0f6a5e5a6d66eb68a5bd49dcaacacb72 223 Pfam PF01209 ubiE/COQ5 methyltransferase family 4 223 8.9E-17 T 31-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 DFR85_03500 0f6a5e5a6d66eb68a5bd49dcaacacb72 223 SUPERFAMILY SSF53335 4 165 2.15E-21 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR85_05585 0bba3329609174bdfc69e89b7b58d90f 382 SUPERFAMILY SSF53383 2 358 1.26E-82 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase DFR85_05585 0bba3329609174bdfc69e89b7b58d90f 382 Pfam PF00266 Aminotransferase class-V 24 323 8.8E-34 T 31-10-2018 IPR000192 Aminotransferase class V domain DFR85_05585 0bba3329609174bdfc69e89b7b58d90f 382 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 173 193 - T 31-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site DFR85_05585 0bba3329609174bdfc69e89b7b58d90f 382 Gene3D G3DSA:3.90.1150.10 4 367 9.0E-103 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 DFR85_05585 0bba3329609174bdfc69e89b7b58d90f 382 PIRSF PIRSF000524 1 378 3.8E-85 T 31-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 DFR85_05585 0bba3329609174bdfc69e89b7b58d90f 382 Gene3D G3DSA:3.40.640.10 9 254 9.0E-103 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR85_12310 875a2b4715ff257225b126066e3ad6ca 358 Gene3D G3DSA:3.20.20.70 28 358 1.3E-52 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_12310 875a2b4715ff257225b126066e3ad6ca 358 Pfam PF13353 4Fe-4S single cluster domain 35 142 1.4E-8 T 31-10-2018 DFR85_12310 875a2b4715ff257225b126066e3ad6ca 358 PIRSF PIRSF037420 12 357 2.5E-97 T 31-10-2018 IPR017200 Coenzyme PQQ synthesis protein E DFR85_12310 875a2b4715ff257225b126066e3ad6ca 358 SUPERFAMILY SSF102114 23 332 1.83E-63 T 31-10-2018 DFR85_12310 875a2b4715ff257225b126066e3ad6ca 358 SMART SM00729 29 224 2.8E-4 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 DFR85_12310 875a2b4715ff257225b126066e3ad6ca 358 Pfam PF04055 Radical SAM superfamily 34 174 5.0E-26 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR85_13630 d47091adecaaec71ff2469dd2215429d 228 Gene3D G3DSA:3.60.21.10 1 221 1.1E-10 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like DFR85_13630 d47091adecaaec71ff2469dd2215429d 228 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 175 1.5E-9 T 31-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 DFR85_13630 d47091adecaaec71ff2469dd2215429d 228 SUPERFAMILY SSF56300 1 176 2.07E-22 T 31-10-2018 DFR85_13060 b3209d9e08aa0097c86c012681d92f93 401 Pfam PF07282 Putative transposase DNA-binding domain 303 372 3.2E-24 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR85_13060 b3209d9e08aa0097c86c012681d92f93 401 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 255 330 2.3E-16 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR85_13060 b3209d9e08aa0097c86c012681d92f93 401 Pfam PF01385 Probable transposase 181 286 1.1E-19 T 31-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 DFR85_05730 6abf1d93ddf295a234b8e3f6f2ba6680 179 Pfam PF01955 Adenosylcobinamide amidohydrolase 11 170 2.7E-20 T 31-10-2018 IPR002808 Adenosylcobinamide amidohydrolase, CbiZ DFR85_04245 8f9dbfe4bc8c1e0552dda39a872717ed 384 Gene3D G3DSA:2.60.120.200 153 338 3.0E-17 T 31-10-2018 DFR85_04245 8f9dbfe4bc8c1e0552dda39a872717ed 384 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 193 334 7.8E-12 T 31-10-2018 DFR85_04245 8f9dbfe4bc8c1e0552dda39a872717ed 384 SUPERFAMILY SSF49899 172 340 1.16E-18 T 31-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily DFR85_06900 ebb615da7255559e86fcfe5f716e1bcd 305 Gene3D G3DSA:1.10.4200.10 35 285 1.4E-36 T 31-10-2018 DFR85_06900 ebb615da7255559e86fcfe5f716e1bcd 305 Pfam PF01874 ATP:dephospho-CoA triphosphoribosyl transferase 19 278 4.5E-35 T 31-10-2018 IPR002736 Triphosphoribosyl-dephospho-CoA protein GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 DFR85_09565 9b91d436c11f5768817442d5ad8716fd 95 Pfam PF01283 Ribosomal protein S26e 1 91 7.3E-26 T 31-10-2018 IPR000892 Ribosomal protein S26e GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_09565 9b91d436c11f5768817442d5ad8716fd 95 Gene3D G3DSA:3.30.1740.20 1 93 1.7E-26 T 31-10-2018 IPR038551 Ribosomal protein S26e superfamily DFR85_12680 b7ee99a94a4a164410c1d16d99ca7eec 281 SUPERFAMILY SSF63829 11 278 3.27E-64 T 31-10-2018 DFR85_12680 b7ee99a94a4a164410c1d16d99ca7eec 281 Gene3D G3DSA:2.120.10.30 1 280 2.7E-94 T 31-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like DFR85_12680 b7ee99a94a4a164410c1d16d99ca7eec 281 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 13 252 3.6E-77 T 31-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region DFR85_12680 b7ee99a94a4a164410c1d16d99ca7eec 281 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 90 111 2.0E-46 T 31-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) DFR85_12680 b7ee99a94a4a164410c1d16d99ca7eec 281 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 192 209 2.0E-46 T 31-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) DFR85_12680 b7ee99a94a4a164410c1d16d99ca7eec 281 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 129 151 2.0E-46 T 31-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) DFR85_12680 b7ee99a94a4a164410c1d16d99ca7eec 281 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 152 172 2.0E-46 T 31-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) DFR85_12680 b7ee99a94a4a164410c1d16d99ca7eec 281 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 234 252 2.0E-46 T 31-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) DFR85_12680 b7ee99a94a4a164410c1d16d99ca7eec 281 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 14 31 2.0E-46 T 31-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) DFR85_04605 6a6522194591129311ede5621cc136ef 442 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 122 145 - T 31-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 DFR85_04605 6a6522194591129311ede5621cc136ef 442 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 221 233 - T 31-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 DFR85_04605 6a6522194591129311ede5621cc136ef 442 Pfam PF00069 Protein kinase domain 116 353 9.9E-47 T 31-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DFR85_04605 6a6522194591129311ede5621cc136ef 442 SMART SM00220 116 360 2.1E-49 T 31-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DFR85_04605 6a6522194591129311ede5621cc136ef 442 SUPERFAMILY SSF56112 110 353 5.13E-65 T 31-10-2018 IPR011009 Protein kinase-like domain superfamily DFR85_04605 6a6522194591129311ede5621cc136ef 442 Gene3D G3DSA:1.10.510.10 105 433 3.3E-65 T 31-10-2018 DFR85_04190 4d4b71d22b19e27765a627f07d242722 679 Pfam PF13802 Galactose mutarotase-like 59 124 1.3E-19 T 31-10-2018 IPR025887 Glycoside hydrolase family 31, N-terminal domain DFR85_04190 4d4b71d22b19e27765a627f07d242722 679 SUPERFAMILY SSF51011 523 596 3.96E-19 T 31-10-2018 DFR85_04190 4d4b71d22b19e27765a627f07d242722 679 SUPERFAMILY SSF74650 44 151 6.59E-24 T 31-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 DFR85_04190 4d4b71d22b19e27765a627f07d242722 679 Gene3D G3DSA:3.20.20.80 151 524 5.7E-147 T 31-10-2018 DFR85_04190 4d4b71d22b19e27765a627f07d242722 679 Gene3D G3DSA:2.60.40.1760 2 150 1.8E-33 T 31-10-2018 DFR85_04190 4d4b71d22b19e27765a627f07d242722 679 SUPERFAMILY SSF51445 154 521 5.09E-80 T 31-10-2018 IPR017853 Glycoside hydrolase superfamily DFR85_04190 4d4b71d22b19e27765a627f07d242722 679 ProSitePatterns PS00129 Glycosyl hydrolases family 31 active site. 313 320 - T 31-10-2018 IPR030458 Glycosyl hydrolases family 31, active site DFR85_04190 4d4b71d22b19e27765a627f07d242722 679 Gene3D G3DSA:2.60.40.1180 525 597 7.5E-28 T 31-10-2018 IPR013780 Glycosyl hydrolase, all-beta DFR85_04190 4d4b71d22b19e27765a627f07d242722 679 Pfam PF01055 Glycosyl hydrolases family 31 145 601 2.2E-134 T 31-10-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 DFR85_04190 4d4b71d22b19e27765a627f07d242722 679 Gene3D G3DSA:2.60.40.1180 598 677 2.1E-5 T 31-10-2018 IPR013780 Glycosyl hydrolase, all-beta DFR85_08090 c59f3dc84997309ab3504f6f1ff5739f 293 ProSitePatterns PS01053 Arginase family signature. 216 237 - T 31-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 DFR85_08090 c59f3dc84997309ab3504f6f1ff5739f 293 SUPERFAMILY SSF52768 24 285 1.22E-76 T 31-10-2018 IPR023696 Ureohydrolase domain superfamily DFR85_08090 c59f3dc84997309ab3504f6f1ff5739f 293 TIGRFAM TIGR01230 agmatinase: agmatinase 25 284 3.2E-70 T 31-10-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 DFR85_08090 c59f3dc84997309ab3504f6f1ff5739f 293 Pfam PF00491 Arginase family 25 283 2.1E-70 T 31-10-2018 IPR006035 Ureohydrolase GO:0046872 DFR85_08090 c59f3dc84997309ab3504f6f1ff5739f 293 PIRSF PIRSF036979 3 292 8.5E-91 T 31-10-2018 IPR006035 Ureohydrolase GO:0046872 DFR85_08090 c59f3dc84997309ab3504f6f1ff5739f 293 Gene3D G3DSA:3.40.800.10 11 291 7.4E-79 T 31-10-2018 DFR85_06675 e6e6fa0131d94d7a4ae8f9f26b6913ae 119 Gene3D G3DSA:3.40.1490.10 1 119 9.7E-47 T 31-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 DFR85_06675 e6e6fa0131d94d7a4ae8f9f26b6913ae 119 Pfam PF01981 Peptidyl-tRNA hydrolase PTH2 1 119 7.3E-41 T 31-10-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 DFR85_06675 e6e6fa0131d94d7a4ae8f9f26b6913ae 119 Hamap MF_00628 Peptidyl-tRNA hydrolase [pth]. 1 119 28.912 T 31-10-2018 IPR034759 Peptidyl-tRNA hydrolase, archaea GO:0004045 MetaCyc: PWY-6308 DFR85_06675 e6e6fa0131d94d7a4ae8f9f26b6913ae 119 SUPERFAMILY SSF102462 1 119 3.31E-40 T 31-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 DFR85_06675 e6e6fa0131d94d7a4ae8f9f26b6913ae 119 TIGRFAM TIGR00283 arch_pth2: peptidyl-tRNA hydrolase 1 119 8.6E-41 T 31-10-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 DFR85_03810 84c9829f3e912b911d9543fe3ce86067 338 Gene3D G3DSA:3.30.1330.10 1 155 5.0E-41 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily DFR85_03810 84c9829f3e912b911d9543fe3ce86067 338 Gene3D G3DSA:3.90.650.10 160 338 1.3E-44 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily DFR85_03810 84c9829f3e912b911d9543fe3ce86067 338 TIGRFAM TIGR02124 hypE: hydrogenase expression/formation protein HypE 3 338 1.7E-108 T 31-10-2018 IPR011854 Carbamoyl dehydratase HypE DFR85_03810 84c9829f3e912b911d9543fe3ce86067 338 SUPERFAMILY SSF55326 4 158 1.26E-27 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily DFR85_03810 84c9829f3e912b911d9543fe3ce86067 338 Pfam PF02769 AIR synthase related protein, C-terminal domain 165 307 5.3E-25 T 31-10-2018 IPR010918 PurM-like, C-terminal domain DFR85_03810 84c9829f3e912b911d9543fe3ce86067 338 SUPERFAMILY SSF56042 161 332 1.17E-35 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily DFR85_03810 84c9829f3e912b911d9543fe3ce86067 338 PIRSF PIRSF005644 1 338 7.6E-102 T 31-10-2018 IPR011854 Carbamoyl dehydratase HypE DFR85_03810 84c9829f3e912b911d9543fe3ce86067 338 Pfam PF00586 AIR synthase related protein, N-terminal domain 44 154 5.6E-16 T 31-10-2018 IPR016188 PurM-like, N-terminal domain DFR85_11905 60fedb3db1ae32e8f7b23f75dcf2af20 51 Gene3D G3DSA:2.10.260.10 1 47 1.5E-18 T 31-10-2018 DFR85_11905 60fedb3db1ae32e8f7b23f75dcf2af20 51 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 7 50 1.2E-10 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR85_11905 60fedb3db1ae32e8f7b23f75dcf2af20 51 SUPERFAMILY SSF89447 5 41 2.96E-10 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily DFR85_11905 60fedb3db1ae32e8f7b23f75dcf2af20 51 SMART SM00966 7 51 3.1E-7 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR85_11905 60fedb3db1ae32e8f7b23f75dcf2af20 51 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 6 48 2.5E-13 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR85_03510 d60624068b36cd9f83beb8277f6248ae 267 Pfam PF13938 Putative heavy-metal chelation 20 98 7.3E-10 T 31-10-2018 IPR025251 Domain of unknown function DUF4213 DFR85_03510 d60624068b36cd9f83beb8277f6248ae 267 Gene3D G3DSA:3.40.50.11590 113 229 1.3E-16 T 31-10-2018 DFR85_03510 d60624068b36cd9f83beb8277f6248ae 267 SUPERFAMILY SSF159713 13 245 6.28E-38 T 31-10-2018 DFR85_03510 d60624068b36cd9f83beb8277f6248ae 267 Pfam PF04016 Putative heavy-metal chelation 123 244 1.1E-22 T 31-10-2018 IPR007161 Putative heavy-metal chelation domain DFR85_03845 2f0e03eb3d26ec585150f3edf0aaf965 163 SUPERFAMILY SSF81301 3 71 7.91E-5 T 31-10-2018 DFR85_14545 71baf1184fbb69c922f0061f58655776 369 PRINTS PR00385 P450 superfamily signature 310 319 5.1E-6 T 31-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 DFR85_14545 71baf1184fbb69c922f0061f58655776 369 PRINTS PR00385 P450 superfamily signature 209 226 5.1E-6 T 31-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 DFR85_14545 71baf1184fbb69c922f0061f58655776 369 PRINTS PR00385 P450 superfamily signature 244 255 5.1E-6 T 31-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 DFR85_14545 71baf1184fbb69c922f0061f58655776 369 PRINTS PR00385 P450 superfamily signature 319 330 5.1E-6 T 31-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 DFR85_14545 71baf1184fbb69c922f0061f58655776 369 Gene3D G3DSA:1.10.630.10 2 369 1.6E-116 T 31-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 DFR85_14545 71baf1184fbb69c922f0061f58655776 369 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 312 321 - T 31-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 DFR85_14545 71baf1184fbb69c922f0061f58655776 369 SUPERFAMILY SSF48264 7 368 5.5E-88 T 31-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 DFR85_14545 71baf1184fbb69c922f0061f58655776 369 Pfam PF00067 Cytochrome P450 156 355 3.8E-30 T 31-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 DFR85_14545 71baf1184fbb69c922f0061f58655776 369 PRINTS PR00359 B-class P450 signature 261 288 3.6E-54 T 31-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DFR85_14545 71baf1184fbb69c922f0061f58655776 369 PRINTS PR00359 B-class P450 signature 289 304 3.6E-54 T 31-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DFR85_14545 71baf1184fbb69c922f0061f58655776 369 PRINTS PR00359 B-class P450 signature 310 319 3.6E-54 T 31-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DFR85_14545 71baf1184fbb69c922f0061f58655776 369 PRINTS PR00359 B-class P450 signature 112 128 3.6E-54 T 31-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DFR85_14545 71baf1184fbb69c922f0061f58655776 369 PRINTS PR00359 B-class P450 signature 129 144 3.6E-54 T 31-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DFR85_14545 71baf1184fbb69c922f0061f58655776 369 PRINTS PR00359 B-class P450 signature 244 255 3.6E-54 T 31-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DFR85_14545 71baf1184fbb69c922f0061f58655776 369 PRINTS PR00359 B-class P450 signature 163 185 3.6E-54 T 31-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DFR85_14545 71baf1184fbb69c922f0061f58655776 369 PRINTS PR00359 B-class P450 signature 319 330 3.6E-54 T 31-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DFR85_14545 71baf1184fbb69c922f0061f58655776 369 PRINTS PR00359 B-class P450 signature 67 78 3.6E-54 T 31-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DFR85_11340 69f254642b90f2ed0aeac7697d763321 94 Pfam PF14947 Winged helix-turn-helix 4 79 5.2E-24 T 31-10-2018 IPR038723 ArnR1-like, winged helix-turn-helix domain DFR85_11340 69f254642b90f2ed0aeac7697d763321 94 SUPERFAMILY SSF46785 5 85 2.1E-11 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_11340 69f254642b90f2ed0aeac7697d763321 94 Gene3D G3DSA:1.10.10.10 3 94 4.7E-21 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_05960 46092d45645a026615ace729e8272b07 307 SUPERFAMILY SSF48452 31 146 1.77E-11 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 DFR85_05960 46092d45645a026615ace729e8272b07 307 Gene3D G3DSA:1.25.40.10 187 306 8.0E-11 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 DFR85_05960 46092d45645a026615ace729e8272b07 307 Gene3D G3DSA:1.25.40.10 1 186 1.6E-15 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 DFR85_05960 46092d45645a026615ace729e8272b07 307 SMART SM00028 76 109 13.0 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 DFR85_05960 46092d45645a026615ace729e8272b07 307 SMART SM00028 39 72 2.9E-4 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 DFR85_05960 46092d45645a026615ace729e8272b07 307 SMART SM00028 274 307 300.0 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 DFR85_05960 46092d45645a026615ace729e8272b07 307 Pfam PF13181 Tetratricopeptide repeat 41 72 3.7E-5 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 DFR85_15640 d9fa0754a15dffb36f1ed0baed382906 598 Gene3D G3DSA:3.40.50.1220 474 598 1.4E-51 T 31-10-2018 DFR85_15640 d9fa0754a15dffb36f1ed0baed382906 598 SMART SM00893 23 216 7.2E-55 T 31-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 DFR85_15640 d9fa0754a15dffb36f1ed0baed382906 598 SMART SM00893 285 465 9.9E-29 T 31-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 DFR85_15640 d9fa0754a15dffb36f1ed0baed382906 598 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 540 566 - T 31-10-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 DFR85_15640 d9fa0754a15dffb36f1ed0baed382906 598 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 478 558 5.4E-33 T 31-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 DFR85_15640 d9fa0754a15dffb36f1ed0baed382906 598 SUPERFAMILY SSF52467 478 596 9.45E-45 T 31-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily DFR85_15640 d9fa0754a15dffb36f1ed0baed382906 598 Gene3D G3DSA:3.40.50.620 283 473 2.9E-55 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR85_15640 d9fa0754a15dffb36f1ed0baed382906 598 Pfam PF01012 Electron transfer flavoprotein domain 286 459 5.0E-34 T 31-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 DFR85_15640 d9fa0754a15dffb36f1ed0baed382906 598 Pfam PF01012 Electron transfer flavoprotein domain 24 211 2.1E-46 T 31-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 DFR85_15640 d9fa0754a15dffb36f1ed0baed382906 598 Gene3D G3DSA:3.40.50.620 2 262 7.6E-88 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR85_15640 d9fa0754a15dffb36f1ed0baed382906 598 SUPERFAMILY SSF52402 285 472 1.19E-43 T 31-10-2018 DFR85_15640 d9fa0754a15dffb36f1ed0baed382906 598 SUPERFAMILY SSF52402 3 259 2.16E-71 T 31-10-2018 DFR85_13980 d985b090ceb8b24d91fe1ac995e8e347 277 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 5 170 1.2E-49 T 31-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 DFR85_13980 d985b090ceb8b24d91fe1ac995e8e347 277 Gene3D G3DSA:3.30.43.10 1 52 2.0E-20 T 31-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 DFR85_13980 d985b090ceb8b24d91fe1ac995e8e347 277 SMART SM01092 176 277 2.3E-28 T 31-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal DFR85_13980 d985b090ceb8b24d91fe1ac995e8e347 277 Gene3D G3DSA:3.30.390.50 175 276 2.3E-30 T 31-10-2018 DFR85_13980 d985b090ceb8b24d91fe1ac995e8e347 277 Gene3D G3DSA:3.30.465.10 58 169 1.6E-40 T 31-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 DFR85_13980 d985b090ceb8b24d91fe1ac995e8e347 277 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 177 275 1.8E-24 T 31-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal DFR85_13980 d985b090ceb8b24d91fe1ac995e8e347 277 SUPERFAMILY SSF56176 1 170 1.8E-53 T 31-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 DFR85_13980 d985b090ceb8b24d91fe1ac995e8e347 277 SUPERFAMILY SSF55447 174 275 9.42E-30 T 31-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily DFR85_08495 df9d02cbcff223740acd848eb0dbf52a 300 Pfam PF10432 Bacterial phospho-glucose isomerase C-terminal SIS domain 169 292 2.1E-19 T 31-10-2018 IPR019490 Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase, C-terminal GO:0004347|GO:0004476|GO:0005975 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00051+5.3.1.8|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.8+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 DFR85_08495 df9d02cbcff223740acd848eb0dbf52a 300 SUPERFAMILY SSF53697 35 288 1.7E-30 T 31-10-2018 DFR85_08495 df9d02cbcff223740acd848eb0dbf52a 300 TIGRFAM TIGR02128 G6PI_arch: bifunctional phosphoglucose/phosphomannose isomerase 14 294 6.2E-78 T 31-10-2018 IPR011857 Bifunctional phosphoglucose/phosphomannose isomerase GO:0004347|GO:0004476|GO:0005975 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00051+5.3.1.8|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.8+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 DFR85_08495 df9d02cbcff223740acd848eb0dbf52a 300 Gene3D G3DSA:3.40.50.10490 5 151 2.8E-27 T 31-10-2018 DFR85_08495 df9d02cbcff223740acd848eb0dbf52a 300 Gene3D G3DSA:3.40.50.10490 161 294 1.9E-17 T 31-10-2018 DFR85_13140 4b54edad5c47764608cd7613c032b62a 588 Pfam PF09484 CRISPR-associated protein TM1802 (cas_TM1802) 1 563 4.2E-61 T 31-10-2018 IPR013389 CRISPR-associated protein Cas8b DFR85_03695 39ab03fb8fc862378c8c80dfd8b5f544 179 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 7.4E-15 T 31-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DFR85_03695 39ab03fb8fc862378c8c80dfd8b5f544 179 Gene3D G3DSA:1.10.357.10 1 178 1.5E-22 T 31-10-2018 DFR85_03695 39ab03fb8fc862378c8c80dfd8b5f544 179 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 2.8E-10 T 31-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DFR85_03695 39ab03fb8fc862378c8c80dfd8b5f544 179 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 2.8E-10 T 31-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 DFR85_03695 39ab03fb8fc862378c8c80dfd8b5f544 179 SUPERFAMILY SSF46689 2 61 4.79E-17 T 31-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 DFR85_12155 1c7a68f997fd257f9d6600ffeaf18e42 217 Gene3D G3DSA:1.10.10.10 140 209 2.4E-17 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_12155 1c7a68f997fd257f9d6600ffeaf18e42 217 SUPERFAMILY SSF46785 145 207 3.39E-10 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_12155 1c7a68f997fd257f9d6600ffeaf18e42 217 TIGRFAM TIGR01884 cas_HTH: CRISPR locus-related DNA-binding protein 3 203 3.5E-34 T 31-10-2018 IPR010163 CRISPR locus-related putative DNA-binding protein Csa3 DFR85_12155 1c7a68f997fd257f9d6600ffeaf18e42 217 Gene3D G3DSA:3.40.50.11700 1 138 9.1E-39 T 31-10-2018 DFR85_12155 1c7a68f997fd257f9d6600ffeaf18e42 217 Pfam PF02082 Transcriptional regulator 150 203 1.7E-6 T 31-10-2018 IPR000944 Transcription regulator Rrf2-type DFR85_14995 20181068de438a7b77c103e23da65d22 489 Gene3D G3DSA:3.40.50.12780 2 387 1.7E-86 T 31-10-2018 DFR85_14995 20181068de438a7b77c103e23da65d22 489 SUPERFAMILY SSF56801 8 486 8.77E-129 T 31-10-2018 DFR85_14995 20181068de438a7b77c103e23da65d22 489 Pfam PF00501 AMP-binding enzyme 8 390 1.7E-83 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 DFR85_14995 20181068de438a7b77c103e23da65d22 489 Pfam PF13193 AMP-binding enzyme C-terminal domain 400 478 2.2E-22 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain DFR85_14995 20181068de438a7b77c103e23da65d22 489 ProSitePatterns PS00455 Putative AMP-binding domain signature. 156 167 - T 31-10-2018 IPR020845 AMP-binding, conserved site DFR85_14995 20181068de438a7b77c103e23da65d22 489 PRINTS PR00154 AMP-binding signature 163 171 9.5E-5 T 31-10-2018 IPR020459 AMP-binding DFR85_14995 20181068de438a7b77c103e23da65d22 489 PRINTS PR00154 AMP-binding signature 151 162 9.5E-5 T 31-10-2018 IPR020459 AMP-binding DFR85_14995 20181068de438a7b77c103e23da65d22 489 Gene3D G3DSA:3.30.300.310 388 489 8.9E-31 T 31-10-2018 DFR85_14115 7394110e248982218a58ea4a4ab5f294 321 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 12 172 6.3E-29 T 31-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_14115 7394110e248982218a58ea4a4ab5f294 321 Gene3D G3DSA:4.10.480.10 194 274 8.0E-18 T 31-10-2018 IPR037148 [NiFe]-hydrogenase, small subunit, C-terminal domain superfamily DFR85_14115 7394110e248982218a58ea4a4ab5f294 321 Pfam PF14720 NiFe/NiFeSe hydrogenase small subunit C-terminal 194 269 2.1E-21 T 31-10-2018 IPR027394 Cytochrome-c3 hydrogenase, C-terminal DFR85_14115 7394110e248982218a58ea4a4ab5f294 321 Gene3D G3DSA:3.40.50.700 1 193 2.0E-52 T 31-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily DFR85_14115 7394110e248982218a58ea4a4ab5f294 321 SUPERFAMILY SSF56770 3 272 2.35E-67 T 31-10-2018 DFR85_14115 7394110e248982218a58ea4a4ab5f294 321 PIRSF PIRSF000310 1 318 5.5E-82 T 31-10-2018 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 DFR85_14115 7394110e248982218a58ea4a4ab5f294 321 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 220 246 3.4E-6 T 31-10-2018 DFR85_14115 7394110e248982218a58ea4a4ab5f294 321 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 96 110 3.4E-6 T 31-10-2018 DFR85_14115 7394110e248982218a58ea4a4ab5f294 321 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 247 260 3.4E-6 T 31-10-2018 DFR85_07310 fd186b5120361d64b219ae019516084a 643 Gene3D G3DSA:3.40.50.10890 390 575 7.9E-146 T 31-10-2018 DFR85_07310 fd186b5120361d64b219ae019516084a 643 SMART SM01027 422 544 4.0E-49 T 31-10-2018 IPR022712 Beta-Casp domain DFR85_07310 fd186b5120361d64b219ae019516084a 643 Pfam PF10996 Beta-Casp domain 423 543 2.5E-22 T 31-10-2018 IPR022712 Beta-Casp domain DFR85_07310 fd186b5120361d64b219ae019516084a 643 SUPERFAMILY SSF56281 182 640 4.66E-129 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR85_07310 fd186b5120361d64b219ae019516084a 643 SMART SM00849 195 410 1.1E-26 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR85_07310 fd186b5120361d64b219ae019516084a 643 Pfam PF17214 KH domain 11 73 3.2E-21 T 31-10-2018 IPR033769 KH domain, archaeal DFR85_07310 fd186b5120361d64b219ae019516084a 643 Gene3D G3DSA:3.60.15.10 188 611 7.9E-146 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR85_07310 fd186b5120361d64b219ae019516084a 643 Pfam PF16661 Metallo-beta-lactamase superfamily domain 200 367 1.4E-13 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR85_07310 fd186b5120361d64b219ae019516084a 643 TIGRFAM TIGR03675 arCOG00543: arCOG00543 universal archaeal KH-domain/beta-lactamase-domain protein 12 642 3.8E-284 T 31-10-2018 IPR019975 KH-domain/beta-lactamase-domain protein, archaea DFR85_07310 fd186b5120361d64b219ae019516084a 643 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 563 619 8.0E-14 T 31-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain DFR85_07310 fd186b5120361d64b219ae019516084a 643 Gene3D G3DSA:3.30.300.20 69 139 4.7E-58 T 31-10-2018 IPR015946 K homology domain-like, alpha/beta DFR85_07310 fd186b5120361d64b219ae019516084a 643 Gene3D G3DSA:3.30.300.230 16 173 4.7E-58 T 31-10-2018 DFR85_15235 1ecf1804da2039c5b86d3ac268496f06 291 SMART SM01092 182 285 9.6E-16 T 31-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal DFR85_15235 1ecf1804da2039c5b86d3ac268496f06 291 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 5 175 5.4E-48 T 31-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 DFR85_15235 1ecf1804da2039c5b86d3ac268496f06 291 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 184 284 8.9E-20 T 31-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal DFR85_15235 1ecf1804da2039c5b86d3ac268496f06 291 Gene3D G3DSA:3.30.43.10 1 55 5.5E-21 T 31-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 DFR85_15235 1ecf1804da2039c5b86d3ac268496f06 291 Gene3D G3DSA:3.30.465.10 60 176 3.2E-37 T 31-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 DFR85_15235 1ecf1804da2039c5b86d3ac268496f06 291 Gene3D G3DSA:3.30.390.50 182 286 2.1E-24 T 31-10-2018 DFR85_15235 1ecf1804da2039c5b86d3ac268496f06 291 SUPERFAMILY SSF55447 183 287 1.96E-20 T 31-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily DFR85_15235 1ecf1804da2039c5b86d3ac268496f06 291 SUPERFAMILY SSF56176 1 175 4.0E-54 T 31-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 DFR85_10770 db8da08f76c8087d88b1849bdd048708 379 Gene3D G3DSA:3.30.56.70 320 378 2.7E-14 T 31-10-2018 DFR85_10770 db8da08f76c8087d88b1849bdd048708 379 TIGRFAM TIGR00308 TRM1: N2,N2-dimethylguanosine tRNA methyltransferase 6 375 4.4E-90 T 31-10-2018 IPR002905 tRNA methyltransferase, Trm1 GO:0003723|GO:0004809|GO:0008033 MetaCyc: PWY-6829 DFR85_10770 db8da08f76c8087d88b1849bdd048708 379 SUPERFAMILY SSF53335 5 371 1.37E-94 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR85_10770 db8da08f76c8087d88b1849bdd048708 379 Gene3D G3DSA:3.40.50.150 1 319 7.5E-91 T 31-10-2018 DFR85_10770 db8da08f76c8087d88b1849bdd048708 379 Hamap MF_00290 tRNA (guanine(26)-N(2))-dimethyltransferase [trm1]. 4 374 38.5 T 31-10-2018 IPR022923 tRNA (guanine(26)-N(2))-dimethyltransferase, archaeal and bacterial GO:0004809 MetaCyc: PWY-6829 DFR85_10770 db8da08f76c8087d88b1849bdd048708 379 Pfam PF02005 N2,N2-dimethylguanosine tRNA methyltransferase 29 369 3.5E-96 T 31-10-2018 IPR002905 tRNA methyltransferase, Trm1 GO:0003723|GO:0004809|GO:0008033 MetaCyc: PWY-6829 DFR85_05845 0bee648f0814e7268cc6d0d8d8f7f53e 371 ProSitePatterns PS00480 Citrate synthase signature. 250 262 - T 31-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 DFR85_05845 0bee648f0814e7268cc6d0d8d8f7f53e 371 Pfam PF00285 Citrate synthase, C-terminal domain 6 353 8.6E-130 T 31-10-2018 IPR002020 Citrate synthase GO:0046912 DFR85_05845 0bee648f0814e7268cc6d0d8d8f7f53e 371 PRINTS PR00143 Citrate synthase signature 303 319 8.8E-48 T 31-10-2018 IPR002020 Citrate synthase GO:0046912 DFR85_05845 0bee648f0814e7268cc6d0d8d8f7f53e 371 PRINTS PR00143 Citrate synthase signature 190 218 8.8E-48 T 31-10-2018 IPR002020 Citrate synthase GO:0046912 DFR85_05845 0bee648f0814e7268cc6d0d8d8f7f53e 371 PRINTS PR00143 Citrate synthase signature 119 132 8.8E-48 T 31-10-2018 IPR002020 Citrate synthase GO:0046912 DFR85_05845 0bee648f0814e7268cc6d0d8d8f7f53e 371 PRINTS PR00143 Citrate synthase signature 168 183 8.8E-48 T 31-10-2018 IPR002020 Citrate synthase GO:0046912 DFR85_05845 0bee648f0814e7268cc6d0d8d8f7f53e 371 PRINTS PR00143 Citrate synthase signature 243 263 8.8E-48 T 31-10-2018 IPR002020 Citrate synthase GO:0046912 DFR85_05845 0bee648f0814e7268cc6d0d8d8f7f53e 371 PRINTS PR00143 Citrate synthase signature 323 337 8.8E-48 T 31-10-2018 IPR002020 Citrate synthase GO:0046912 DFR85_05845 0bee648f0814e7268cc6d0d8d8f7f53e 371 Gene3D G3DSA:1.10.580.10 18 342 7.1E-135 T 31-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 DFR85_05845 0bee648f0814e7268cc6d0d8d8f7f53e 371 SUPERFAMILY SSF48256 4 370 6.28E-135 T 31-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 DFR85_05845 0bee648f0814e7268cc6d0d8d8f7f53e 371 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 5 370 2.0E-146 T 31-10-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 DFR85_05845 0bee648f0814e7268cc6d0d8d8f7f53e 371 PIRSF PIRSF001369 1 371 1.1E-144 T 31-10-2018 IPR024176 Citrate synthase, bacterial-type DFR85_05845 0bee648f0814e7268cc6d0d8d8f7f53e 371 Gene3D G3DSA:1.10.230.10 216 317 7.1E-135 T 31-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain DFR85_14375 06a4167f85103fc82ee34dcb35e2876a 410 Gene3D G3DSA:3.50.50.60 8 311 9.0E-96 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_14375 06a4167f85103fc82ee34dcb35e2876a 410 Gene3D G3DSA:3.30.390.30 323 410 1.9E-14 T 31-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 DFR85_14375 06a4167f85103fc82ee34dcb35e2876a 410 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 1.0E-12 T 31-10-2018 DFR85_14375 06a4167f85103fc82ee34dcb35e2876a 410 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 148 173 1.0E-12 T 31-10-2018 DFR85_14375 06a4167f85103fc82ee34dcb35e2876a 410 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 234 248 1.0E-12 T 31-10-2018 DFR85_14375 06a4167f85103fc82ee34dcb35e2876a 410 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 273 280 1.0E-12 T 31-10-2018 DFR85_14375 06a4167f85103fc82ee34dcb35e2876a 410 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 303 1.5E-62 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR85_14375 06a4167f85103fc82ee34dcb35e2876a 410 Gene3D G3DSA:3.50.50.60 116 240 9.0E-96 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_14375 06a4167f85103fc82ee34dcb35e2876a 410 Pfam PF14759 Reductase C-terminal 323 409 5.9E-15 T 31-10-2018 IPR028202 Reductase, C-terminal DFR85_14375 06a4167f85103fc82ee34dcb35e2876a 410 SUPERFAMILY SSF55424 315 409 7.83E-19 T 31-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 DFR85_14375 06a4167f85103fc82ee34dcb35e2876a 410 SUPERFAMILY SSF51905 3 338 2.56E-43 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_14375 06a4167f85103fc82ee34dcb35e2876a 410 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 233 249 1.9E-25 T 31-10-2018 DFR85_14375 06a4167f85103fc82ee34dcb35e2876a 410 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.9E-25 T 31-10-2018 DFR85_14375 06a4167f85103fc82ee34dcb35e2876a 410 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 103 121 1.9E-25 T 31-10-2018 DFR85_14375 06a4167f85103fc82ee34dcb35e2876a 410 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 280 1.9E-25 T 31-10-2018 DFR85_14375 06a4167f85103fc82ee34dcb35e2876a 410 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 1.9E-25 T 31-10-2018 DFR85_09680 497e3f3cbe4d18c7daa6fa8af8b886b3 165 Gene3D G3DSA:1.20.120.1200 10 163 1.4E-9 T 31-10-2018 DFR85_09680 497e3f3cbe4d18c7daa6fa8af8b886b3 165 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 23 161 2.5E-15 T 31-10-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_03215 f07d5ca795686973276cf3268990032c 400 Gene3D G3DSA:1.20.1250.20 2 382 1.9E-27 T 31-10-2018 DFR85_03215 f07d5ca795686973276cf3268990032c 400 SUPERFAMILY SSF103473 5 394 5.93E-35 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_03215 f07d5ca795686973276cf3268990032c 400 Pfam PF05977 Transmembrane secretion effector 11 391 4.1E-17 T 31-10-2018 IPR010290 Transmembrane secretion effector DFR85_03995 5ee29bf188cecbb2d4efb0ac705c4cb6 320 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 119 2.7E-15 T 31-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 DFR85_03995 5ee29bf188cecbb2d4efb0ac705c4cb6 320 SUPERFAMILY SSF51735 1 184 1.77E-33 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_03995 5ee29bf188cecbb2d4efb0ac705c4cb6 320 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 141 191 1.3E-4 T 31-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 DFR85_03995 5ee29bf188cecbb2d4efb0ac705c4cb6 320 Gene3D G3DSA:3.30.360.10 126 317 1.5E-58 T 31-10-2018 DFR85_03995 5ee29bf188cecbb2d4efb0ac705c4cb6 320 SUPERFAMILY SSF55347 126 292 2.35E-27 T 31-10-2018 DFR85_03995 5ee29bf188cecbb2d4efb0ac705c4cb6 320 Gene3D G3DSA:3.40.50.720 4 299 1.5E-58 T 31-10-2018 DFR85_05690 15f9baec5266bcec9c8c8f632db2cd17 263 Pfam PF00515 Tetratricopeptide repeat 190 223 7.3E-8 T 31-10-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 DFR85_05690 15f9baec5266bcec9c8c8f632db2cd17 263 Gene3D G3DSA:1.25.40.10 207 262 2.2E-14 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 DFR85_05690 15f9baec5266bcec9c8c8f632db2cd17 263 Pfam PF13181 Tetratricopeptide repeat 34 59 0.0021 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 DFR85_05690 15f9baec5266bcec9c8c8f632db2cd17 263 Pfam PF13181 Tetratricopeptide repeat 226 254 0.0039 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 DFR85_05690 15f9baec5266bcec9c8c8f632db2cd17 263 Gene3D G3DSA:1.25.40.10 116 206 2.1E-17 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 DFR85_05690 15f9baec5266bcec9c8c8f632db2cd17 263 SMART SM00028 156 189 6.5E-4 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 DFR85_05690 15f9baec5266bcec9c8c8f632db2cd17 263 SMART SM00028 33 66 220.0 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 DFR85_05690 15f9baec5266bcec9c8c8f632db2cd17 263 SMART SM00028 190 223 9.4E-7 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 DFR85_05690 15f9baec5266bcec9c8c8f632db2cd17 263 SMART SM00028 224 257 12.0 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 DFR85_05690 15f9baec5266bcec9c8c8f632db2cd17 263 SMART SM00028 122 155 12.0 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 DFR85_05690 15f9baec5266bcec9c8c8f632db2cd17 263 SMART SM00028 88 121 190.0 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 DFR85_05690 15f9baec5266bcec9c8c8f632db2cd17 263 SUPERFAMILY SSF48452 15 152 2.07E-11 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 DFR85_05690 15f9baec5266bcec9c8c8f632db2cd17 263 Pfam PF07719 Tetratricopeptide repeat 156 188 3.4E-5 T 31-10-2018 IPR013105 Tetratricopeptide repeat 2 DFR85_05690 15f9baec5266bcec9c8c8f632db2cd17 263 Gene3D G3DSA:1.25.40.10 1 115 1.2E-8 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 DFR85_05690 15f9baec5266bcec9c8c8f632db2cd17 263 SUPERFAMILY SSF48452 121 254 2.11E-32 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 DFR85_06390 965d4d14dc6b4676020779004b6cce8a 104 Pfam PF08279 HTH domain 6 51 5.1E-6 T 31-10-2018 IPR013196 Helix-turn-helix, type 11 DFR85_06390 965d4d14dc6b4676020779004b6cce8a 104 Gene3D G3DSA:1.10.10.10 1 101 7.4E-8 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_06390 965d4d14dc6b4676020779004b6cce8a 104 SUPERFAMILY SSF46785 1 90 4.02E-9 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_11135 6d8de7e33bcbf5119240cac4d2011b77 500 SUPERFAMILY SSF111352 58 453 1.26E-102 T 31-10-2018 DFR85_11135 6d8de7e33bcbf5119240cac4d2011b77 500 ProSitePatterns PS01219 Ammonium transporters signature. 226 251 - T 31-10-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 DFR85_11135 6d8de7e33bcbf5119240cac4d2011b77 500 PRINTS PR00342 Rhesus blood group protein signature 170 186 6.7E-5 T 31-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 DFR85_11135 6d8de7e33bcbf5119240cac4d2011b77 500 PRINTS PR00342 Rhesus blood group protein signature 384 400 6.7E-5 T 31-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 DFR85_11135 6d8de7e33bcbf5119240cac4d2011b77 500 PRINTS PR00342 Rhesus blood group protein signature 295 317 6.7E-5 T 31-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 DFR85_11135 6d8de7e33bcbf5119240cac4d2011b77 500 PRINTS PR00342 Rhesus blood group protein signature 264 282 6.7E-5 T 31-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 DFR85_11135 6d8de7e33bcbf5119240cac4d2011b77 500 Gene3D G3DSA:1.10.3430.10 39 491 1.3E-121 T 31-10-2018 IPR029020 Ammonium/urea transporter DFR85_11135 6d8de7e33bcbf5119240cac4d2011b77 500 TIGRFAM TIGR00836 amt: ammonium transporter 63 472 1.4E-109 T 31-10-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 DFR85_11135 6d8de7e33bcbf5119240cac4d2011b77 500 Pfam PF00909 Ammonium Transporter Family 65 472 2.9E-92 T 31-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 DFR85_02175 87e5cabff870d04d647fcf77f397f4db 306 Gene3D G3DSA:3.40.50.970 22 199 1.4E-24 T 31-10-2018 DFR85_02175 87e5cabff870d04d647fcf77f397f4db 306 Pfam PF12367 Pyruvate ferredoxin oxidoreductase beta subunit C terminal 199 271 1.3E-21 T 31-10-2018 IPR032686 Pyruvate ferredoxin oxidoreductase beta subunit, C-terminal DFR85_02175 87e5cabff870d04d647fcf77f397f4db 306 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 46 195 1.9E-29 T 31-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 DFR85_02175 87e5cabff870d04d647fcf77f397f4db 306 TIGRFAM TIGR02177 PorB_KorB: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family 12 302 1.3E-126 T 31-10-2018 IPR011896 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate DFR85_02175 87e5cabff870d04d647fcf77f397f4db 306 SUPERFAMILY SSF52518 12 270 6.88E-71 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR85_13430 a7c7ec461ee37f8fc93839523238210d 108 Pfam PF01909 Nucleotidyltransferase domain 18 59 5.2E-9 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 DFR85_13430 a7c7ec461ee37f8fc93839523238210d 108 SUPERFAMILY SSF81301 17 99 1.75E-16 T 31-10-2018 DFR85_13430 a7c7ec461ee37f8fc93839523238210d 108 Gene3D G3DSA:3.30.460.10 12 107 1.6E-23 T 31-10-2018 DFR85_07675 1ef688a9c784c1fec16871eb87419310 581 SUPERFAMILY SSF102114 125 398 1.16E-37 T 31-10-2018 DFR85_07675 1ef688a9c784c1fec16871eb87419310 581 Pfam PF04055 Radical SAM superfamily 141 305 1.8E-19 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR85_07675 1ef688a9c784c1fec16871eb87419310 581 Gene3D G3DSA:3.20.20.70 130 402 2.1E-29 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_07675 1ef688a9c784c1fec16871eb87419310 581 Pfam PF13394 4Fe-4S single cluster domain 142 230 5.3E-6 T 31-10-2018 DFR85_07455 28281aa52a12d942bb22ac1874bf7ea5 600 SMART SM00382 98 295 3.5E-5 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_07455 28281aa52a12d942bb22ac1874bf7ea5 600 SMART SM00382 367 522 2.1E-8 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_07455 28281aa52a12d942bb22ac1874bf7ea5 600 SUPERFAMILY SSF54862 4 118 1.36E-18 T 31-10-2018 DFR85_07455 28281aa52a12d942bb22ac1874bf7ea5 600 PRINTS PR01868 ABC transporter family E signature 152 178 3.0E-54 T 31-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 DFR85_07455 28281aa52a12d942bb22ac1874bf7ea5 600 PRINTS PR01868 ABC transporter family E signature 136 152 3.0E-54 T 31-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 DFR85_07455 28281aa52a12d942bb22ac1874bf7ea5 600 PRINTS PR01868 ABC transporter family E signature 75 95 3.0E-54 T 31-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 DFR85_07455 28281aa52a12d942bb22ac1874bf7ea5 600 PRINTS PR01868 ABC transporter family E signature 19 34 3.0E-54 T 31-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 DFR85_07455 28281aa52a12d942bb22ac1874bf7ea5 600 PRINTS PR01868 ABC transporter family E signature 48 72 3.0E-54 T 31-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 DFR85_07455 28281aa52a12d942bb22ac1874bf7ea5 600 PRINTS PR01868 ABC transporter family E signature 103 128 3.0E-54 T 31-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 DFR85_07455 28281aa52a12d942bb22ac1874bf7ea5 600 Pfam PF00005 ABC transporter 96 240 3.5E-15 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR85_07455 28281aa52a12d942bb22ac1874bf7ea5 600 SUPERFAMILY SSF52540 96 287 1.68E-28 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_07455 28281aa52a12d942bb22ac1874bf7ea5 600 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 51 62 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR85_07455 28281aa52a12d942bb22ac1874bf7ea5 600 ProSitePatterns PS00211 ABC transporters family signature. 213 227 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DFR85_07455 28281aa52a12d942bb22ac1874bf7ea5 600 Pfam PF00037 4Fe-4S binding domain 44 67 1.1E-7 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR85_07455 28281aa52a12d942bb22ac1874bf7ea5 600 Pfam PF04068 Possible Fer4-like domain in RNase L inhibitor, RLI 2 32 8.3E-13 T 31-10-2018 IPR007209 RNase L inhibitor RLI, possible metal-binding domain DFR85_07455 28281aa52a12d942bb22ac1874bf7ea5 600 Pfam PF00005 ABC transporter 365 487 2.3E-18 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR85_07455 28281aa52a12d942bb22ac1874bf7ea5 600 Gene3D G3DSA:3.40.50.300 328 595 2.2E-59 T 31-10-2018 DFR85_07455 28281aa52a12d942bb22ac1874bf7ea5 600 Gene3D G3DSA:3.40.50.300 1 327 8.1E-71 T 31-10-2018 DFR85_07455 28281aa52a12d942bb22ac1874bf7ea5 600 SUPERFAMILY SSF52540 364 534 4.32E-34 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_09320 9accfd17a2e50d8f86d6402b43bc2b89 450 Gene3D G3DSA:3.50.50.60 3 321 1.7E-97 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_09320 9accfd17a2e50d8f86d6402b43bc2b89 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 36 51 1.9E-57 T 31-10-2018 DFR85_09320 9accfd17a2e50d8f86d6402b43bc2b89 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 165 190 1.9E-57 T 31-10-2018 DFR85_09320 9accfd17a2e50d8f86d6402b43bc2b89 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 295 302 1.9E-57 T 31-10-2018 DFR85_09320 9accfd17a2e50d8f86d6402b43bc2b89 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 393 408 1.9E-57 T 31-10-2018 DFR85_09320 9accfd17a2e50d8f86d6402b43bc2b89 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 252 266 1.9E-57 T 31-10-2018 DFR85_09320 9accfd17a2e50d8f86d6402b43bc2b89 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 129 138 1.9E-57 T 31-10-2018 DFR85_09320 9accfd17a2e50d8f86d6402b43bc2b89 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.9E-57 T 31-10-2018 DFR85_09320 9accfd17a2e50d8f86d6402b43bc2b89 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 329 350 1.9E-57 T 31-10-2018 DFR85_09320 9accfd17a2e50d8f86d6402b43bc2b89 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 415 435 1.9E-57 T 31-10-2018 DFR85_09320 9accfd17a2e50d8f86d6402b43bc2b89 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 165 183 1.1E-30 T 31-10-2018 DFR85_09320 9accfd17a2e50d8f86d6402b43bc2b89 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 126 144 1.1E-30 T 31-10-2018 DFR85_09320 9accfd17a2e50d8f86d6402b43bc2b89 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 280 302 1.1E-30 T 31-10-2018 DFR85_09320 9accfd17a2e50d8f86d6402b43bc2b89 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.1E-30 T 31-10-2018 DFR85_09320 9accfd17a2e50d8f86d6402b43bc2b89 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 251 267 1.1E-30 T 31-10-2018 DFR85_09320 9accfd17a2e50d8f86d6402b43bc2b89 450 SUPERFAMILY SSF51905 1 324 8.48E-49 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_09320 9accfd17a2e50d8f86d6402b43bc2b89 450 SUPERFAMILY SSF55424 331 442 1.89E-33 T 31-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 DFR85_09320 9accfd17a2e50d8f86d6402b43bc2b89 450 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 3 444 1.0E-123 T 31-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 DFR85_09320 9accfd17a2e50d8f86d6402b43bc2b89 450 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 333 440 1.1E-28 T 31-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 DFR85_09320 9accfd17a2e50d8f86d6402b43bc2b89 450 PIRSF PIRSF000350 1 445 1.4E-84 T 31-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 DFR85_09320 9accfd17a2e50d8f86d6402b43bc2b89 450 Gene3D G3DSA:3.30.390.30 331 449 3.4E-32 T 31-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 DFR85_09320 9accfd17a2e50d8f86d6402b43bc2b89 450 Gene3D G3DSA:3.50.50.60 138 258 1.7E-97 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_09320 9accfd17a2e50d8f86d6402b43bc2b89 450 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 315 6.7E-65 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR85_01955 12999a8696000ee8edc54c13f0229da4 740 Pfam PF00271 Helicase conserved C-terminal domain 267 367 3.5E-16 T 31-10-2018 IPR001650 Helicase, C-terminal DFR85_01955 12999a8696000ee8edc54c13f0229da4 740 Gene3D G3DSA:3.40.50.300 33 232 4.5E-41 T 31-10-2018 DFR85_01955 12999a8696000ee8edc54c13f0229da4 740 SUPERFAMILY SSF52540 65 380 2.77E-49 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_01955 12999a8696000ee8edc54c13f0229da4 740 SMART SM00487 52 252 7.5E-32 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain DFR85_01955 12999a8696000ee8edc54c13f0229da4 740 Pfam PF09369 Domain of unknown function (DUF1998) 627 699 2.8E-11 T 31-10-2018 IPR018973 DEAD/DEAH-box helicase, putative DFR85_01955 12999a8696000ee8edc54c13f0229da4 740 SMART SM00490 287 368 3.1E-17 T 31-10-2018 IPR001650 Helicase, C-terminal DFR85_01955 12999a8696000ee8edc54c13f0229da4 740 Pfam PF00270 DEAD/DEAH box helicase 58 219 1.5E-25 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 DFR85_01955 12999a8696000ee8edc54c13f0229da4 740 Gene3D G3DSA:3.40.50.300 255 471 1.2E-25 T 31-10-2018 DFR85_03800 5036ef9703bcf0448406a57810b9cb6c 395 TIGRFAM TIGR00075 hypD: hydrogenase expression/formation protein HypD 20 384 1.6E-108 T 31-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 DFR85_03800 5036ef9703bcf0448406a57810b9cb6c 395 Gene3D G3DSA:3.40.50.11740 72 317 7.4E-94 T 31-10-2018 DFR85_03800 5036ef9703bcf0448406a57810b9cb6c 395 Pfam PF01924 Hydrogenase formation hypA family 26 381 3.0E-118 T 31-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 DFR85_03800 5036ef9703bcf0448406a57810b9cb6c 395 PIRSF PIRSF005622 9 387 4.8E-129 T 31-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 DFR85_03800 5036ef9703bcf0448406a57810b9cb6c 395 Gene3D G3DSA:1.10.10.2140 334 384 7.8E-21 T 31-10-2018 DFR85_03800 5036ef9703bcf0448406a57810b9cb6c 395 Gene3D G3DSA:3.40.50.11750 37 277 7.4E-94 T 31-10-2018 DFR85_11705 b585c128ca41e498ad3aeed10200080e 174 Pfam PF04250 Protein of unknown function (DUF429) 4 93 1.4E-4 T 31-10-2018 IPR007362 Protein of unknown function DUF429 DFR85_11705 b585c128ca41e498ad3aeed10200080e 174 PIRSF PIRSF024051 1 161 4.5E-46 T 31-10-2018 IPR018036 Protein of unknown function DUF429, subgroup DFR85_11205 6fe1d39930f43db814087989149177ff 151 SUPERFAMILY SSF55282 3 143 1.27E-42 T 31-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_11205 6fe1d39930f43db814087989149177ff 151 Hamap MF_01112 UPF0201 protein . 2 134 27.055 T 31-10-2018 IPR002739 Uncharacterised protein family UPF0201 DFR85_11205 6fe1d39930f43db814087989149177ff 151 Gene3D G3DSA:3.30.1440.10 1 136 5.4E-40 T 31-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_11205 6fe1d39930f43db814087989149177ff 151 Pfam PF01877 RNA binding 3 115 9.2E-14 T 31-10-2018 IPR002739 Uncharacterised protein family UPF0201 DFR85_04270 fc798087855226fad893e9fba86b2b4e 335 Pfam PF00535 Glycosyl transferase family 2 5 140 2.6E-18 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 DFR85_04270 fc798087855226fad893e9fba86b2b4e 335 Gene3D G3DSA:3.90.550.10 1 260 1.1E-29 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_04270 fc798087855226fad893e9fba86b2b4e 335 SUPERFAMILY SSF53448 2 219 3.7E-37 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_07085 8da8b10e4a11837ba558acdba8dccf48 140 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 38 128 23.131 T 31-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07085 8da8b10e4a11837ba558acdba8dccf48 140 ProSitePatterns PS00323 Ribosomal protein S19 signature. 92 116 - T 31-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07085 8da8b10e4a11837ba558acdba8dccf48 140 SUPERFAMILY SSF54570 40 123 2.75E-25 T 31-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07085 8da8b10e4a11837ba558acdba8dccf48 140 PRINTS PR00975 Ribosomal protein S19 family signature 92 104 6.2E-14 T 31-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07085 8da8b10e4a11837ba558acdba8dccf48 140 PRINTS PR00975 Ribosomal protein S19 family signature 72 91 6.2E-14 T 31-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07085 8da8b10e4a11837ba558acdba8dccf48 140 PRINTS PR00975 Ribosomal protein S19 family signature 104 119 6.2E-14 T 31-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07085 8da8b10e4a11837ba558acdba8dccf48 140 Pfam PF00203 Ribosomal protein S19 40 122 3.6E-31 T 31-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07085 8da8b10e4a11837ba558acdba8dccf48 140 TIGRFAM TIGR01025 uS19_arch: ribosomal protein uS19 10 139 4.0E-59 T 31-10-2018 IPR005713 Ribosomal protein S19A/S15e GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07085 8da8b10e4a11837ba558acdba8dccf48 140 Gene3D G3DSA:3.30.860.20 7 139 4.8E-50 T 31-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07085 8da8b10e4a11837ba558acdba8dccf48 140 PIRSF PIRSF002144 3 139 2.5E-36 T 31-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_09045 791acc1a99b2aafccf51536423fd3f9f 152 Gene3D G3DSA:3.40.50.150 1 152 7.7E-27 T 31-10-2018 DFR85_09045 791acc1a99b2aafccf51536423fd3f9f 152 Pfam PF08123 Histone methylation protein DOT1 10 68 1.2E-5 T 31-10-2018 IPR025789 Histone-lysine N-methyltransferase DOT1 domain GO:0018024 KEGG: 00310+2.1.1.43|Reactome: R-HSA-3214841 DFR85_09045 791acc1a99b2aafccf51536423fd3f9f 152 SUPERFAMILY SSF53335 4 147 2.07E-19 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR85_01335 737fb9b8fd86b748ed5116d4878d7b51 142 PRINTS PR00421 Thioredoxin family signature 58 66 2.2E-7 T 31-10-2018 DFR85_01335 737fb9b8fd86b748ed5116d4878d7b51 142 PRINTS PR00421 Thioredoxin family signature 66 75 2.2E-7 T 31-10-2018 DFR85_01335 737fb9b8fd86b748ed5116d4878d7b51 142 PRINTS PR00421 Thioredoxin family signature 105 116 2.2E-7 T 31-10-2018 DFR85_01335 737fb9b8fd86b748ed5116d4878d7b51 142 TIGRFAM TIGR01068 thioredoxin: thioredoxin 44 139 3.3E-34 T 31-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 DFR85_01335 737fb9b8fd86b748ed5116d4878d7b51 142 Gene3D G3DSA:3.40.30.10 7 142 2.5E-36 T 31-10-2018 DFR85_01335 737fb9b8fd86b748ed5116d4878d7b51 142 ProSitePatterns PS00194 Thioredoxin family active site. 59 77 - T 31-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 DFR85_01335 737fb9b8fd86b748ed5116d4878d7b51 142 SUPERFAMILY SSF52833 4 141 2.76E-39 T 31-10-2018 IPR036249 Thioredoxin-like superfamily DFR85_01335 737fb9b8fd86b748ed5116d4878d7b51 142 PIRSF PIRSF000077 37 141 2.3E-32 T 31-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 DFR85_01335 737fb9b8fd86b748ed5116d4878d7b51 142 Pfam PF00085 Thioredoxin 40 138 5.6E-28 T 31-10-2018 IPR013766 Thioredoxin domain GO:0045454 DFR85_02525 4497790cbfc6c47258046956d386ddc7 198 Gene3D G3DSA:1.10.4190.10 4 176 3.2E-27 T 31-10-2018 IPR038277 UreF domain superfamily DFR85_02525 4497790cbfc6c47258046956d386ddc7 198 PIRSF PIRSF009467 3 198 5.4E-32 T 31-10-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 DFR85_02525 4497790cbfc6c47258046956d386ddc7 198 Pfam PF01730 UreF 63 164 1.0E-15 T 31-10-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 DFR85_01710 542ae98c751e3aae44b7de0e4d4c6ed1 429 Pfam PF01385 Probable transposase 194 299 5.7E-13 T 31-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 DFR85_01710 542ae98c751e3aae44b7de0e4d4c6ed1 429 Pfam PF07282 Putative transposase DNA-binding domain 315 380 5.8E-23 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR85_01710 542ae98c751e3aae44b7de0e4d4c6ed1 429 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 264 342 1.2E-17 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR85_04760 0ac51c3e785b957eb945d6e9839b1337 161 Gene3D G3DSA:3.40.50.1010 1 156 9.8E-29 T 31-10-2018 DFR85_04760 0ac51c3e785b957eb945d6e9839b1337 161 SUPERFAMILY SSF88723 1 138 1.12E-16 T 31-10-2018 IPR029060 PIN-like domain superfamily DFR85_04760 0ac51c3e785b957eb945d6e9839b1337 161 Pfam PF01850 PIN domain 2 136 1.8E-5 T 31-10-2018 IPR002716 PIN domain DFR85_07600 b97e25dd1438143ea5a94fae72f5c87f 186 Gene3D G3DSA:2.40.320.10 4 182 4.6E-43 T 31-10-2018 DFR85_07600 b97e25dd1438143ea5a94fae72f5c87f 186 SUPERFAMILY SSF55154 5 174 1.36E-38 T 31-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 DFR85_07600 b97e25dd1438143ea5a94fae72f5c87f 186 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 4 142 1.0E-28 T 31-10-2018 DFR85_07600 b97e25dd1438143ea5a94fae72f5c87f 186 Pfam PF01928 CYTH domain 5 160 2.5E-32 T 31-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 DFR85_07600 b97e25dd1438143ea5a94fae72f5c87f 186 SMART SM01118 4 176 4.9E-12 T 31-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 DFR85_07600 b97e25dd1438143ea5a94fae72f5c87f 186 TIGRFAM TIGR00318 cyaB: putative adenylyl cyclase CyaB 5 174 4.2E-41 T 31-10-2018 IPR008173 Adenylyl cyclase CyaB KEGG: 00230+4.6.1.1 DFR85_05820 73fe6bef55cd3087b0f142196fe2dfb6 199 Gene3D G3DSA:3.40.50.850 7 197 1.2E-56 T 31-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 DFR85_05820 73fe6bef55cd3087b0f142196fe2dfb6 199 SUPERFAMILY SSF52499 8 195 1.1E-59 T 31-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 DFR85_05820 73fe6bef55cd3087b0f142196fe2dfb6 199 Pfam PF00857 Isochorismatase family 21 180 4.9E-40 T 31-10-2018 IPR000868 Isochorismatase-like GO:0003824 DFR85_07840 abf716509459bf3c3f21762430e1f711 904 Pfam PF08494 DEAD/H associated 581 748 1.8E-16 T 31-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 DFR85_07840 abf716509459bf3c3f21762430e1f711 904 SMART SM00382 32 207 0.0087 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_07840 abf716509459bf3c3f21762430e1f711 904 Gene3D G3DSA:3.40.50.300 6 209 7.3E-49 T 31-10-2018 DFR85_07840 abf716509459bf3c3f21762430e1f711 904 Pfam PF00271 Helicase conserved C-terminal domain 241 344 2.0E-21 T 31-10-2018 IPR001650 Helicase, C-terminal DFR85_07840 abf716509459bf3c3f21762430e1f711 904 SMART SM00487 15 212 7.5E-43 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain DFR85_07840 abf716509459bf3c3f21762430e1f711 904 SMART SM00490 265 344 2.5E-19 T 31-10-2018 IPR001650 Helicase, C-terminal DFR85_07840 abf716509459bf3c3f21762430e1f711 904 Pfam PF00270 DEAD/DEAH box helicase 20 187 1.8E-32 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 DFR85_07840 abf716509459bf3c3f21762430e1f711 904 Gene3D G3DSA:3.40.50.300 235 371 1.4E-29 T 31-10-2018 DFR85_07840 abf716509459bf3c3f21762430e1f711 904 PIRSF PIRSF037307 2 904 1.4E-284 T 31-10-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 DFR85_07840 abf716509459bf3c3f21762430e1f711 904 SUPERFAMILY SSF52540 27 354 7.95E-52 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_14140 bc7a380769b9942413555b57f26c3313 235 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 20 195 5.9E-42 T 31-10-2018 IPR001303 Class II aldolase/adducin N-terminal DFR85_14140 bc7a380769b9942413555b57f26c3313 235 Gene3D G3DSA:3.40.225.10 10 224 1.4E-57 T 31-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily DFR85_14140 bc7a380769b9942413555b57f26c3313 235 SUPERFAMILY SSF53639 12 219 1.35E-48 T 31-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily DFR85_14140 bc7a380769b9942413555b57f26c3313 235 SMART SM01007 19 199 1.5E-49 T 31-10-2018 IPR001303 Class II aldolase/adducin N-terminal DFR85_10050 42e9b4ee6740ceeb187c69643058ed2f 201 SMART SM00382 21 197 1.1E-5 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_10050 42e9b4ee6740ceeb187c69643058ed2f 201 Pfam PF00005 ABC transporter 17 149 1.3E-24 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR85_10050 42e9b4ee6740ceeb187c69643058ed2f 201 SUPERFAMILY SSF52540 16 197 4.46E-33 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_10050 42e9b4ee6740ceeb187c69643058ed2f 201 Gene3D G3DSA:3.40.50.300 4 200 1.2E-37 T 31-10-2018 DFR85_14080 3ab2d5f641d9a409cd847c50e1fa744a 152 SUPERFAMILY SSF75169 6 137 1.79E-8 T 31-10-2018 IPR027396 DsrEFH-like DFR85_14080 3ab2d5f641d9a409cd847c50e1fa744a 152 Gene3D G3DSA:3.40.1260.10 1 152 4.7E-19 T 31-10-2018 IPR027396 DsrEFH-like DFR85_05510 32106510b6c4216e981b8c8df42d01e6 288 SUPERFAMILY SSF117892 94 212 1.2E-9 T 31-10-2018 IPR036013 Band 7/SPFH domain superfamily DFR85_05510 32106510b6c4216e981b8c8df42d01e6 288 Pfam PF01145 SPFH domain / Band 7 family 42 218 2.4E-22 T 31-10-2018 IPR001107 Band 7 domain DFR85_05510 32106510b6c4216e981b8c8df42d01e6 288 Gene3D G3DSA:3.30.479.30 97 208 1.4E-5 T 31-10-2018 DFR85_15410 f87427e0a6784e3edc59fbbc9f2118b0 342 SUPERFAMILY SSF47240 3 267 1.03E-31 T 31-10-2018 IPR009078 Ferritin-like superfamily DFR85_15410 f87427e0a6784e3edc59fbbc9f2118b0 342 Gene3D G3DSA:1.10.620.20 3 252 8.7E-14 T 31-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 DFR85_13905 93a3ea63bb83e3988d96f57fe8c93ce7 282 SUPERFAMILY SSF52540 2 225 2.52E-51 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_13905 93a3ea63bb83e3988d96f57fe8c93ce7 282 Gene3D G3DSA:3.40.50.300 1 232 1.8E-52 T 31-10-2018 DFR85_13905 93a3ea63bb83e3988d96f57fe8c93ce7 282 Pfam PF00005 ABC transporter 17 153 1.8E-25 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR85_13905 93a3ea63bb83e3988d96f57fe8c93ce7 282 SMART SM00382 26 203 2.2E-9 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_03650 73cbc22f1255f51bf0e2401367545125 399 Gene3D G3DSA:1.20.1250.20 7 197 7.0E-8 T 31-10-2018 DFR85_03650 73cbc22f1255f51bf0e2401367545125 399 Gene3D G3DSA:1.20.1250.20 218 393 3.7E-10 T 31-10-2018 DFR85_03650 73cbc22f1255f51bf0e2401367545125 399 SUPERFAMILY SSF103473 1 392 1.12E-26 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_03650 73cbc22f1255f51bf0e2401367545125 399 Pfam PF07690 Major Facilitator Superfamily 15 315 5.7E-10 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_14340 6b10e975e2156a52e52b8f2018daf261 375 SUPERFAMILY SSF47240 38 374 1.89E-66 T 31-10-2018 IPR009078 Ferritin-like superfamily DFR85_14340 6b10e975e2156a52e52b8f2018daf261 375 Pfam PF02332 Methane/Phenol/Toluene Hydroxylase 95 321 7.5E-52 T 31-10-2018 IPR003430 Methane/phenol/toluene hydroxylase GO:0006725|GO:0055114 DFR85_14340 6b10e975e2156a52e52b8f2018daf261 375 Gene3D G3DSA:1.10.620.20 38 373 9.0E-91 T 31-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 DFR85_14340 6b10e975e2156a52e52b8f2018daf261 375 PIRSF PIRSF000040 5 375 2.6E-95 T 31-10-2018 IPR012078 Methane/phenol monooxygenase, hydroxylase component GO:0016709|GO:0055114 DFR85_10880 2855705b8ebf0bc3c654d7eee3c9e4b1 1150 SMART SM00436 726 812 4.1E-30 T 31-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 DFR85_10880 2855705b8ebf0bc3c654d7eee3c9e4b1 1150 Gene3D G3DSA:2.60.510.20 807 1038 1.2E-130 T 31-10-2018 DFR85_10880 2855705b8ebf0bc3c654d7eee3c9e4b1 1150 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1054 1068 6.5E-26 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 DFR85_10880 2855705b8ebf0bc3c654d7eee3c9e4b1 1150 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 699 712 6.5E-26 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 DFR85_10880 2855705b8ebf0bc3c654d7eee3c9e4b1 1150 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 885 894 6.5E-26 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 DFR85_10880 2855705b8ebf0bc3c654d7eee3c9e4b1 1150 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 785 803 6.5E-26 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 DFR85_10880 2855705b8ebf0bc3c654d7eee3c9e4b1 1150 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 965 981 6.5E-26 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 DFR85_10880 2855705b8ebf0bc3c654d7eee3c9e4b1 1150 Gene3D G3DSA:3.40.50.300 70 285 6.6E-47 T 31-10-2018 DFR85_10880 2855705b8ebf0bc3c654d7eee3c9e4b1 1150 SMART SM00493 573 725 1.3E-27 T 31-10-2018 IPR006171 TOPRIM domain DFR85_10880 2855705b8ebf0bc3c654d7eee3c9e4b1 1150 Gene3D G3DSA:1.10.290.10 853 976 1.2E-130 T 31-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 DFR85_10880 2855705b8ebf0bc3c654d7eee3c9e4b1 1150 TIGRFAM TIGR01054 rgy: reverse gyrase 1 1139 2.2E-300 T 31-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 DFR85_10880 2855705b8ebf0bc3c654d7eee3c9e4b1 1150 Gene3D G3DSA:3.40.50.140 573 755 6.0E-26 T 31-10-2018 DFR85_10880 2855705b8ebf0bc3c654d7eee3c9e4b1 1150 SUPERFAMILY SSF56712 572 1140 1.31E-123 T 31-10-2018 IPR023405 DNA topoisomerase, type IA, core domain DFR85_10880 2855705b8ebf0bc3c654d7eee3c9e4b1 1150 SUPERFAMILY SSF52540 300 564 5.03E-25 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_10880 2855705b8ebf0bc3c654d7eee3c9e4b1 1150 SUPERFAMILY SSF52540 43 272 1.22E-17 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_10880 2855705b8ebf0bc3c654d7eee3c9e4b1 1150 Pfam PF01751 Toprim domain 575 735 1.1E-20 T 31-10-2018 IPR006171 TOPRIM domain DFR85_10880 2855705b8ebf0bc3c654d7eee3c9e4b1 1150 Hamap MF_01125 Reverse gyrase [rgy]. 1 1141 56.848 T 31-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 DFR85_10880 2855705b8ebf0bc3c654d7eee3c9e4b1 1150 Pfam PF00270 DEAD/DEAH box helicase 99 269 1.6E-5 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 DFR85_10880 2855705b8ebf0bc3c654d7eee3c9e4b1 1150 Pfam PF01131 DNA topoisomerase 750 1128 6.2E-69 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 DFR85_10880 2855705b8ebf0bc3c654d7eee3c9e4b1 1150 SMART SM00437 843 1093 2.0E-81 T 31-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 DFR85_10880 2855705b8ebf0bc3c654d7eee3c9e4b1 1150 Gene3D G3DSA:1.10.460.10 756 1133 1.2E-130 T 31-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 DFR85_10880 2855705b8ebf0bc3c654d7eee3c9e4b1 1150 SMART SM00487 85 245 5.9E-13 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain DFR85_11100 554e68ba0ba415ee0ccc73a7b3379725 440 SUPERFAMILY SSF53756 39 433 7.18E-57 T 31-10-2018 DFR85_11100 554e68ba0ba415ee0ccc73a7b3379725 440 Gene3D G3DSA:3.40.50.2000 234 416 1.2E-42 T 31-10-2018 DFR85_11100 554e68ba0ba415ee0ccc73a7b3379725 440 Pfam PF00534 Glycosyl transferases group 1 240 405 3.5E-35 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 DFR85_11100 554e68ba0ba415ee0ccc73a7b3379725 440 Gene3D G3DSA:3.40.50.2000 31 233 4.6E-7 T 31-10-2018 DFR85_08895 bcf735cb18ea3d684f173d1b6c4158fc 117 ProSitePatterns PS01106 Ribosomal protein L18e signature. 31 48 - T 31-10-2018 IPR021132 Ribosomal protein L18e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_08895 bcf735cb18ea3d684f173d1b6c4158fc 117 Hamap MF_00329 50S ribosomal protein L18e [rpl18e]. 4 117 25.383 T 31-10-2018 IPR022947 Ribosomal protein L18e, archaea DFR85_08895 bcf735cb18ea3d684f173d1b6c4158fc 117 Gene3D G3DSA:3.100.10.10 5 116 4.0E-30 T 31-10-2018 DFR85_08895 bcf735cb18ea3d684f173d1b6c4158fc 117 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 54 96 3.7E-7 T 31-10-2018 IPR021131 Ribosomal protein L18e/L15P DFR85_08895 bcf735cb18ea3d684f173d1b6c4158fc 117 ProSitePatterns PS00475 Ribosomal protein L15 signature. 63 93 - T 31-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_08895 bcf735cb18ea3d684f173d1b6c4158fc 117 SUPERFAMILY SSF52080 6 116 8.5E-23 T 31-10-2018 IPR036227 Ribosomal L18e/L15P superfamily DFR85_10630 dd0d5dfca704e484235387c2c8fd8f0c 444 SUPERFAMILY SSF55021 295 386 6.11E-11 T 31-10-2018 DFR85_10630 dd0d5dfca704e484235387c2c8fd8f0c 444 PIRSF PIRSF000726 1 444 8.5E-70 T 31-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 DFR85_10630 dd0d5dfca704e484235387c2c8fd8f0c 444 Gene3D G3DSA:3.30.2130.10 293 441 1.7E-16 T 31-10-2018 DFR85_10630 dd0d5dfca704e484235387c2c8fd8f0c 444 Gene3D G3DSA:3.40.1160.10 1 290 2.4E-71 T 31-10-2018 IPR036393 Acetylglutamate kinase-like superfamily DFR85_10630 dd0d5dfca704e484235387c2c8fd8f0c 444 SUPERFAMILY SSF53633 1 283 3.14E-58 T 31-10-2018 IPR036393 Acetylglutamate kinase-like superfamily DFR85_10630 dd0d5dfca704e484235387c2c8fd8f0c 444 Pfam PF00696 Amino acid kinase family 2 276 1.3E-42 T 31-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 DFR85_10630 dd0d5dfca704e484235387c2c8fd8f0c 444 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 2 439 2.1E-84 T 31-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 DFR85_06225 7db46fab12161e0e032dc04e358c9960 643 ProSitePatterns PS00455 Putative AMP-binding domain signature. 248 259 - T 31-10-2018 IPR020845 AMP-binding, conserved site DFR85_06225 7db46fab12161e0e032dc04e358c9960 643 Gene3D G3DSA:3.30.300.30 507 638 6.3E-29 T 31-10-2018 DFR85_06225 7db46fab12161e0e032dc04e358c9960 643 Pfam PF13193 AMP-binding enzyme C-terminal domain 520 598 1.2E-24 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain DFR85_06225 7db46fab12161e0e032dc04e358c9960 643 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 18 630 6.6E-268 T 31-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 DFR85_06225 7db46fab12161e0e032dc04e358c9960 643 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 18 72 5.6E-22 T 31-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 DFR85_06225 7db46fab12161e0e032dc04e358c9960 643 Gene3D G3DSA:3.40.50.12780 46 505 2.3E-107 T 31-10-2018 DFR85_06225 7db46fab12161e0e032dc04e358c9960 643 SUPERFAMILY SSF56801 17 628 2.62E-170 T 31-10-2018 DFR85_06225 7db46fab12161e0e032dc04e358c9960 643 Pfam PF00501 AMP-binding enzyme 74 511 2.6E-92 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 DFR85_13745 ccfae41b5ba3e547bbd8a4e05fa0848d 525 Gene3D G3DSA:3.80.30.20 208 418 1.6E-20 T 31-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe DFR85_13745 ccfae41b5ba3e547bbd8a4e05fa0848d 525 SUPERFAMILY SSF102114 212 435 1.44E-14 T 31-10-2018 DFR85_13745 ccfae41b5ba3e547bbd8a4e05fa0848d 525 Pfam PF04055 Radical SAM superfamily 213 395 1.1E-12 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR85_13745 ccfae41b5ba3e547bbd8a4e05fa0848d 525 SMART SM00729 208 440 3.6E-17 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 DFR85_03945 e40085868433421843dd685a7aa74e71 128 SMART SM00748 7 119 6.3E-41 T 31-10-2018 IPR007842 HEPN domain DFR85_03945 e40085868433421843dd685a7aa74e71 128 Gene3D G3DSA:1.20.120.330 1 128 2.0E-35 T 31-10-2018 DFR85_03945 e40085868433421843dd685a7aa74e71 128 Pfam PF05168 HEPN domain 3 125 6.3E-34 T 31-10-2018 IPR007842 HEPN domain DFR85_03945 e40085868433421843dd685a7aa74e71 128 SUPERFAMILY SSF81593 3 126 2.47E-37 T 31-10-2018 DFR85_06760 4188d9e021cafffc8c4080fda25243e8 598 SUPERFAMILY SSF56091 231 435 4.8E-49 T 31-10-2018 DFR85_06760 4188d9e021cafffc8c4080fda25243e8 598 Gene3D G3DSA:3.30.470.30 232 437 1.2E-76 T 31-10-2018 DFR85_06760 4188d9e021cafffc8c4080fda25243e8 598 Pfam PF01068 ATP dependent DNA ligase domain 235 435 5.4E-64 T 31-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 DFR85_06760 4188d9e021cafffc8c4080fda25243e8 598 Pfam PF04675 DNA ligase N terminus 2 184 1.0E-38 T 31-10-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 DFR85_06760 4188d9e021cafffc8c4080fda25243e8 598 SUPERFAMILY SSF50249 444 586 7.8E-46 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR85_06760 4188d9e021cafffc8c4080fda25243e8 598 TIGRFAM TIGR00574 dnl1: DNA ligase I, ATP-dependent (dnl1) 59 583 6.3E-184 T 31-10-2018 IPR000977 DNA ligase, ATP-dependent GO:0003910|GO:0005524|GO:0006281|GO:0006310|GO:0071897 DFR85_06760 4188d9e021cafffc8c4080fda25243e8 598 ProSitePatterns PS00333 ATP-dependent DNA ligase signature 2. 409 435 - T 31-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 DFR85_06760 4188d9e021cafffc8c4080fda25243e8 598 Pfam PF04679 ATP dependent DNA ligase C terminal region 461 568 1.1E-25 T 31-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 DFR85_06760 4188d9e021cafffc8c4080fda25243e8 598 Gene3D G3DSA:1.10.3260.10 1 231 1.4E-77 T 31-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 DFR85_06760 4188d9e021cafffc8c4080fda25243e8 598 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 258 266 - T 31-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 DFR85_06760 4188d9e021cafffc8c4080fda25243e8 598 Gene3D G3DSA:2.40.50.140 438 597 5.5E-61 T 31-10-2018 DFR85_06760 4188d9e021cafffc8c4080fda25243e8 598 SUPERFAMILY SSF117018 2 239 1.57E-65 T 31-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 DFR85_06760 4188d9e021cafffc8c4080fda25243e8 598 Hamap MF_00407 DNA ligase [lig]. 1 584 31.378 T 31-10-2018 IPR022865 DNA ligase, ATP-dependent, bacterial/archaeal GO:0003910 DFR85_01975 3e09731ce576933ba881035bafd98edf 572 Pfam PF00384 Molybdopterin oxidoreductase 314 379 5.6E-8 T 31-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_01975 3e09731ce576933ba881035bafd98edf 572 Gene3D G3DSA:3.40.228.10 111 298 4.5E-63 T 31-10-2018 DFR85_01975 3e09731ce576933ba881035bafd98edf 572 Gene3D G3DSA:3.30.2070.10 370 449 4.5E-63 T 31-10-2018 DFR85_01975 3e09731ce576933ba881035bafd98edf 572 Gene3D G3DSA:3.40.50.740 54 413 4.5E-63 T 31-10-2018 DFR85_01975 3e09731ce576933ba881035bafd98edf 572 SUPERFAMILY SSF53706 5 457 2.49E-66 T 31-10-2018 DFR85_06125 cfa15a07741faf01c7520f5d68a924df 309 PRINTS PR00958 Homoserine kinase signature 93 108 3.6E-25 T 31-10-2018 DFR85_06125 cfa15a07741faf01c7520f5d68a924df 309 PRINTS PR00958 Homoserine kinase signature 133 146 3.6E-25 T 31-10-2018 DFR85_06125 cfa15a07741faf01c7520f5d68a924df 309 PRINTS PR00958 Homoserine kinase signature 173 190 3.6E-25 T 31-10-2018 DFR85_06125 cfa15a07741faf01c7520f5d68a924df 309 PRINTS PR00958 Homoserine kinase signature 252 267 3.6E-25 T 31-10-2018 DFR85_06125 cfa15a07741faf01c7520f5d68a924df 309 PRINTS PR00958 Homoserine kinase signature 10 25 3.6E-25 T 31-10-2018 DFR85_06125 cfa15a07741faf01c7520f5d68a924df 309 Pfam PF00288 GHMP kinases N terminal domain 80 146 1.0E-13 T 31-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 DFR85_06125 cfa15a07741faf01c7520f5d68a924df 309 SUPERFAMILY SSF54211 1 156 5.69E-30 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold DFR85_06125 cfa15a07741faf01c7520f5d68a924df 309 Hamap MF_00384 Homoserine kinase [thrB]. 5 307 26.421 T 31-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 DFR85_06125 cfa15a07741faf01c7520f5d68a924df 309 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 86 97 - T 31-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 DFR85_06125 cfa15a07741faf01c7520f5d68a924df 309 Gene3D G3DSA:3.30.230.10 1 165 1.2E-39 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup DFR85_06125 cfa15a07741faf01c7520f5d68a924df 309 PIRSF PIRSF000676 1 308 9.6E-79 T 31-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 DFR85_06125 cfa15a07741faf01c7520f5d68a924df 309 TIGRFAM TIGR00191 thrB: homoserine kinase 7 297 4.6E-57 T 31-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 DFR85_06125 cfa15a07741faf01c7520f5d68a924df 309 Gene3D G3DSA:3.30.70.890 166 297 3.3E-28 T 31-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily DFR85_06125 cfa15a07741faf01c7520f5d68a924df 309 SUPERFAMILY SSF55060 166 287 9.71E-24 T 31-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily DFR85_06125 cfa15a07741faf01c7520f5d68a924df 309 Pfam PF08544 GHMP kinases C terminal 212 279 4.4E-6 T 31-10-2018 IPR013750 GHMP kinase, C-terminal domain DFR85_06050 7efc6e15c6118f4ff27317603d6c9bdc 178 SUPERFAMILY SSF56300 1 171 1.11E-13 T 31-10-2018 DFR85_06050 7efc6e15c6118f4ff27317603d6c9bdc 178 Gene3D G3DSA:3.60.21.10 1 177 4.5E-9 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like DFR85_15335 36f32da517e18266051cd7c5ed3b625a 373 SUPERFAMILY SSF53901 2 214 4.06E-25 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR85_15335 36f32da517e18266051cd7c5ed3b625a 373 PIRSF PIRSF000429 1 370 2.8E-35 T 31-10-2018 IPR002155 Thiolase GO:0016747 DFR85_15335 36f32da517e18266051cd7c5ed3b625a 373 Gene3D G3DSA:3.40.47.10 1 373 2.2E-111 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR85_15335 36f32da517e18266051cd7c5ed3b625a 373 SUPERFAMILY SSF53901 235 359 2.07E-21 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR85_15335 36f32da517e18266051cd7c5ed3b625a 373 Pfam PF00108 Thiolase, N-terminal domain 33 211 5.2E-19 T 31-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 DFR85_07730 65f67e1a22d398d959a22d313e024859 406 Gene3D G3DSA:3.40.50.10380 1 138 2.3E-63 T 31-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 DFR85_07730 65f67e1a22d398d959a22d313e024859 406 SMART SM01274 1 129 1.0E-64 T 31-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 DFR85_07730 65f67e1a22d398d959a22d313e024859 406 Pfam PF03949 Malic enzyme, NAD binding domain 142 368 7.3E-21 T 31-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 DFR85_07730 65f67e1a22d398d959a22d313e024859 406 SUPERFAMILY SSF51735 141 400 4.86E-69 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_07730 65f67e1a22d398d959a22d313e024859 406 PIRSF PIRSF000106 15 405 2.7E-79 T 31-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 DFR85_07730 65f67e1a22d398d959a22d313e024859 406 Pfam PF00390 Malic enzyme, N-terminal domain 11 129 2.0E-22 T 31-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 DFR85_07730 65f67e1a22d398d959a22d313e024859 406 SMART SM00919 141 373 4.3E-105 T 31-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 DFR85_07730 65f67e1a22d398d959a22d313e024859 406 Gene3D G3DSA:3.40.50.720 139 406 9.3E-86 T 31-10-2018 DFR85_07730 65f67e1a22d398d959a22d313e024859 406 SUPERFAMILY SSF53223 2 139 9.35E-51 T 31-10-2018 DFR85_06425 6df9c12b570aeb95f37c25349f67fb3a 249 Pfam PF02654 Cobalamin-5-phosphate synthase 11 232 3.1E-31 T 31-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 DFR85_06425 6df9c12b570aeb95f37c25349f67fb3a 249 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 4 233 5.9E-33 T 31-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 DFR85_03430 aeaa5f22b4075d0bb016960c5df68b72 1035 Gene3D G3DSA:3.40.50.740 50 939 1.3E-111 T 31-10-2018 DFR85_03430 aeaa5f22b4075d0bb016960c5df68b72 1035 Pfam PF00384 Molybdopterin oxidoreductase 119 635 2.5E-31 T 31-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_03430 aeaa5f22b4075d0bb016960c5df68b72 1035 SMART SM00926 58 116 5.6E-12 T 31-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_03430 aeaa5f22b4075d0bb016960c5df68b72 1035 SUPERFAMILY SSF53706 55 656 7.37E-108 T 31-10-2018 DFR85_03430 aeaa5f22b4075d0bb016960c5df68b72 1035 SUPERFAMILY SSF50692 852 998 2.71E-12 T 31-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily DFR85_03430 aeaa5f22b4075d0bb016960c5df68b72 1035 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 60 116 1.6E-11 T 31-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_03430 aeaa5f22b4075d0bb016960c5df68b72 1035 Pfam PF01568 Molydopterin dinucleotide binding domain 878 965 2.2E-7 T 31-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 DFR85_03430 aeaa5f22b4075d0bb016960c5df68b72 1035 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 11 30 7.5E-4 T 31-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal DFR85_03430 aeaa5f22b4075d0bb016960c5df68b72 1035 Pfam PF10518 TAT (twin-arginine translocation) pathway signal sequence 11 32 3.9E-5 T 31-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal DFR85_06265 0f4cac82b02215befe8f340374a20a00 313 Gene3D G3DSA:3.40.50.720 2 308 2.0E-123 T 31-10-2018 DFR85_06265 0f4cac82b02215befe8f340374a20a00 313 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 3 312 1.7E-32 T 31-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 DFR85_06265 0f4cac82b02215befe8f340374a20a00 313 Gene3D G3DSA:3.40.50.720 96 281 2.0E-123 T 31-10-2018 DFR85_06265 0f4cac82b02215befe8f340374a20a00 313 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 220 236 - T 31-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site DFR85_06265 0f4cac82b02215befe8f340374a20a00 313 SUPERFAMILY SSF51735 101 282 7.14E-59 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_06265 0f4cac82b02215befe8f340374a20a00 313 SUPERFAMILY SSF52283 1 130 6.24E-38 T 31-10-2018 DFR85_06265 0f4cac82b02215befe8f340374a20a00 313 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 107 281 1.6E-62 T 31-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 DFR85_15540 ea971ea2a1747e661d75b8b1fb154996 414 Pfam PF04143 Sulphur transport 34 406 2.2E-62 T 31-10-2018 IPR007272 Sulphur transport domain DFR85_01645 dc581e52380639753a6650a5c438f752 733 Gene3D G3DSA:3.30.365.10 353 717 4.2E-111 T 31-10-2018 DFR85_01645 dc581e52380639753a6650a5c438f752 733 SUPERFAMILY SSF56003 114 728 3.53E-173 T 31-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 DFR85_01645 dc581e52380639753a6650a5c438f752 733 Gene3D G3DSA:3.90.1170.50 1 121 1.0E-34 T 31-10-2018 DFR85_01645 dc581e52380639753a6650a5c438f752 733 SUPERFAMILY SSF54665 2 136 1.7E-37 T 31-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily DFR85_01645 dc581e52380639753a6650a5c438f752 733 SMART SM01008 21 122 2.8E-39 T 31-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DFR85_01645 dc581e52380639753a6650a5c438f752 733 Gene3D G3DSA:3.30.365.10 141 344 9.3E-64 T 31-10-2018 DFR85_01645 dc581e52380639753a6650a5c438f752 733 Gene3D G3DSA:3.30.365.10 436 593 4.2E-111 T 31-10-2018 DFR85_01645 dc581e52380639753a6650a5c438f752 733 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 21 121 5.1E-25 T 31-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DFR85_01645 dc581e52380639753a6650a5c438f752 733 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 142 675 1.3E-154 T 31-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DFR85_01645 dc581e52380639753a6650a5c438f752 733 Gene3D G3DSA:3.30.365.10 176 270 9.3E-64 T 31-10-2018 DFR85_00915 0fdba7d174ceac93c892e8b487355879 334 TIGRFAM TIGR03399 RNA_3prim_cycl: RNA 3'-phosphate cyclase 2 318 4.1E-111 T 31-10-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 DFR85_00915 0fdba7d174ceac93c892e8b487355879 334 SUPERFAMILY SSF55205 1 225 6.47E-52 T 31-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 DFR85_00915 0fdba7d174ceac93c892e8b487355879 334 Gene3D G3DSA:3.30.360.20 180 272 3.0E-101 T 31-10-2018 IPR036553 RNA 3'-terminal phosphate cyclase, insert domain superfamily DFR85_00915 0fdba7d174ceac93c892e8b487355879 334 ProSitePatterns PS01287 RNA 3'-terminal phosphate cyclase signature. 153 163 - T 31-10-2018 IPR020719 RNA 3'-terminal phosphate cyclase-like, conserved site DFR85_00915 0fdba7d174ceac93c892e8b487355879 334 Gene3D G3DSA:3.65.10.20 3 316 3.0E-101 T 31-10-2018 IPR037136 RNA 3'-terminal phosphate cyclase domain superfamily DFR85_00915 0fdba7d174ceac93c892e8b487355879 334 Hamap MF_00200 RNA 3'-terminal phosphate cyclase [rtcA]. 1 332 35.528 T 31-10-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 DFR85_00915 0fdba7d174ceac93c892e8b487355879 334 Pfam PF01137 RNA 3'-terminal phosphate cyclase 9 317 1.2E-65 T 31-10-2018 IPR023797 RNA 3'-terminal phosphate cyclase domain DFR85_00915 0fdba7d174ceac93c892e8b487355879 334 Pfam PF05189 RNA 3'-terminal phosphate cyclase (RTC), insert domain 178 271 7.9E-19 T 31-10-2018 IPR013791 RNA 3'-terminal phosphate cyclase, insert domain DFR85_00915 0fdba7d174ceac93c892e8b487355879 334 PIRSF PIRSF005378 1 328 1.9E-103 T 31-10-2018 IPR000228 RNA 3'-terminal phosphate cyclase GO:0006396 DFR85_00255 371f0a250e5f0f5d209d9793e1a83a2f 496 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 223 277 - T 31-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_00255 371f0a250e5f0f5d209d9793e1a83a2f 496 Gene3D G3DSA:1.20.210.10 6 485 2.6E-70 T 31-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_00255 371f0a250e5f0f5d209d9793e1a83a2f 496 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 11 450 4.3E-65 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_00255 371f0a250e5f0f5d209d9793e1a83a2f 496 PRINTS PR01165 Cytochrome c oxidase subunit I signature 267 282 1.2E-19 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_00255 371f0a250e5f0f5d209d9793e1a83a2f 496 PRINTS PR01165 Cytochrome c oxidase subunit I signature 291 312 1.2E-19 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_00255 371f0a250e5f0f5d209d9793e1a83a2f 496 PRINTS PR01165 Cytochrome c oxidase subunit I signature 328 346 1.2E-19 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_00255 371f0a250e5f0f5d209d9793e1a83a2f 496 PRINTS PR01165 Cytochrome c oxidase subunit I signature 221 242 1.2E-19 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_00255 371f0a250e5f0f5d209d9793e1a83a2f 496 PRINTS PR01165 Cytochrome c oxidase subunit I signature 356 375 1.2E-19 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_00255 371f0a250e5f0f5d209d9793e1a83a2f 496 PRINTS PR01165 Cytochrome c oxidase subunit I signature 52 75 1.2E-19 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_00255 371f0a250e5f0f5d209d9793e1a83a2f 496 SUPERFAMILY SSF81442 7 476 4.97E-72 T 31-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_07030 fa655ba148e0a2e93923c44d9849552c 133 ProSitePatterns PS00053 Ribosomal protein S8 signature. 103 120 - T 31-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07030 fa655ba148e0a2e93923c44d9849552c 133 SUPERFAMILY SSF56047 3 133 7.98E-37 T 31-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07030 fa655ba148e0a2e93923c44d9849552c 133 Hamap MF_01302_A 30S ribosomal protein S8 [rpsH]. 2 133 34.921 T 31-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07030 fa655ba148e0a2e93923c44d9849552c 133 Gene3D G3DSA:3.30.1490.10 70 131 9.1E-23 T 31-10-2018 DFR85_07030 fa655ba148e0a2e93923c44d9849552c 133 Pfam PF00410 Ribosomal protein S8 6 133 3.3E-24 T 31-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07030 fa655ba148e0a2e93923c44d9849552c 133 Gene3D G3DSA:3.30.1370.30 1 69 2.2E-32 T 31-10-2018 DFR85_08105 68ebe6415135af21861b27703ec836df 308 Pfam PF08271 TFIIB zinc-binding 14 51 8.8E-11 T 31-10-2018 IPR013137 Zinc finger, TFIIB-type DFR85_08105 68ebe6415135af21861b27703ec836df 308 Hamap MF_00383 Transcription initiation factor IIB [tfb]. 5 305 43.851 T 31-10-2018 IPR023484 Transcription initiation factor TFIIB, archaea DFR85_08105 68ebe6415135af21861b27703ec836df 308 SUPERFAMILY SSF47954 215 306 6.19E-29 T 31-10-2018 IPR036915 Cyclin-like superfamily DFR85_08105 68ebe6415135af21861b27703ec836df 308 SUPERFAMILY SSF47954 121 212 1.7E-25 T 31-10-2018 IPR036915 Cyclin-like superfamily DFR85_08105 68ebe6415135af21861b27703ec836df 308 Gene3D G3DSA:1.10.472.10 216 307 3.0E-25 T 31-10-2018 DFR85_08105 68ebe6415135af21861b27703ec836df 308 SUPERFAMILY SSF57783 13 54 6.21E-11 T 31-10-2018 DFR85_08105 68ebe6415135af21861b27703ec836df 308 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 158 173 - T 31-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 DFR85_08105 68ebe6415135af21861b27703ec836df 308 SMART SM00385 218 299 1.7E-11 T 31-10-2018 IPR013763 Cyclin-like DFR85_08105 68ebe6415135af21861b27703ec836df 308 SMART SM00385 124 205 5.5E-11 T 31-10-2018 IPR013763 Cyclin-like DFR85_08105 68ebe6415135af21861b27703ec836df 308 Gene3D G3DSA:1.10.472.170 12 207 2.2E-61 T 31-10-2018 DFR85_08105 68ebe6415135af21861b27703ec836df 308 PRINTS PR00685 Transcription initiation factor IIB signature 58 79 7.2E-56 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 DFR85_08105 68ebe6415135af21861b27703ec836df 308 PRINTS PR00685 Transcription initiation factor IIB signature 219 237 7.2E-56 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 DFR85_08105 68ebe6415135af21861b27703ec836df 308 PRINTS PR00685 Transcription initiation factor IIB signature 166 185 7.2E-56 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 DFR85_08105 68ebe6415135af21861b27703ec836df 308 PRINTS PR00685 Transcription initiation factor IIB signature 253 269 7.2E-56 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 DFR85_08105 68ebe6415135af21861b27703ec836df 308 PRINTS PR00685 Transcription initiation factor IIB signature 45 58 7.2E-56 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 DFR85_08105 68ebe6415135af21861b27703ec836df 308 PRINTS PR00685 Transcription initiation factor IIB signature 285 299 7.2E-56 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 DFR85_08105 68ebe6415135af21861b27703ec836df 308 PRINTS PR00685 Transcription initiation factor IIB signature 192 207 7.2E-56 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 DFR85_08105 68ebe6415135af21861b27703ec836df 308 PRINTS PR00685 Transcription initiation factor IIB signature 23 43 7.2E-56 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 DFR85_08105 68ebe6415135af21861b27703ec836df 308 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 252 267 - T 31-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 DFR85_08105 68ebe6415135af21861b27703ec836df 308 Pfam PF00382 Transcription factor TFIIB repeat 128 195 7.3E-16 T 31-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 DFR85_08105 68ebe6415135af21861b27703ec836df 308 Pfam PF00382 Transcription factor TFIIB repeat 221 290 6.6E-16 T 31-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 DFR85_03415 cbf36ae832fbe82f5fe02cd2b6996d47 476 Gene3D G3DSA:3.30.70.20 325 378 4.5E-11 T 31-10-2018 DFR85_03415 cbf36ae832fbe82f5fe02cd2b6996d47 476 SUPERFAMILY SSF54862 132 213 3.59E-18 T 31-10-2018 DFR85_03415 cbf36ae832fbe82f5fe02cd2b6996d47 476 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 177 188 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR85_03415 cbf36ae832fbe82f5fe02cd2b6996d47 476 SUPERFAMILY SSF54862 323 376 1.45E-15 T 31-10-2018 DFR85_03415 cbf36ae832fbe82f5fe02cd2b6996d47 476 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 363 374 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR85_03415 cbf36ae832fbe82f5fe02cd2b6996d47 476 Gene3D G3DSA:3.30.70.20 136 212 1.2E-13 T 31-10-2018 DFR85_03415 cbf36ae832fbe82f5fe02cd2b6996d47 476 Pfam PF12838 4Fe-4S dicluster domain 330 376 6.4E-8 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR85_03415 cbf36ae832fbe82f5fe02cd2b6996d47 476 Pfam PF00037 4Fe-4S binding domain 171 193 9.8E-9 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR85_14405 610cddfa2b7292e5b45ef4c788829444 562 Gene3D G3DSA:3.40.50.970 358 533 5.8E-86 T 31-10-2018 DFR85_14405 610cddfa2b7292e5b45ef4c788829444 562 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 391 533 7.8E-31 T 31-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 DFR85_14405 610cddfa2b7292e5b45ef4c788829444 562 SUPERFAMILY SSF52467 153 357 5.01E-40 T 31-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily DFR85_14405 610cddfa2b7292e5b45ef4c788829444 562 Gene3D G3DSA:3.40.50.1220 200 357 5.8E-86 T 31-10-2018 DFR85_14405 610cddfa2b7292e5b45ef4c788829444 562 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 170 1.7E-45 T 31-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 DFR85_14405 610cddfa2b7292e5b45ef4c788829444 562 Gene3D G3DSA:3.40.50.970 1 176 6.8E-45 T 31-10-2018 DFR85_14405 610cddfa2b7292e5b45ef4c788829444 562 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 193 327 2.4E-34 T 31-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 DFR85_14405 610cddfa2b7292e5b45ef4c788829444 562 SUPERFAMILY SSF52518 362 547 9.32E-41 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR85_14405 610cddfa2b7292e5b45ef4c788829444 562 SUPERFAMILY SSF52518 1 172 3.17E-39 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR85_15520 1f802d4d6a4ef191b8f0ada0bb11d55d 476 ProSitePatterns PS00216 Sugar transport proteins signature 1. 86 102 - T 31-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DFR85_15520 1f802d4d6a4ef191b8f0ada0bb11d55d 476 Gene3D G3DSA:1.20.1250.20 21 475 9.0E-69 T 31-10-2018 DFR85_15520 1f802d4d6a4ef191b8f0ada0bb11d55d 476 Pfam PF00083 Sugar (and other) transporter 34 475 8.4E-44 T 31-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 DFR85_15520 1f802d4d6a4ef191b8f0ada0bb11d55d 476 SUPERFAMILY SSF103473 15 474 3.66E-70 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_15520 1f802d4d6a4ef191b8f0ada0bb11d55d 476 ProSitePatterns PS00217 Sugar transport proteins signature 2. 128 153 - T 31-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DFR85_09905 35f8bb9e93186274094d56b26aa89c06 446 SUPERFAMILY SSF58100 310 423 3.92E-6 T 31-10-2018 DFR85_09905 35f8bb9e93186274094d56b26aa89c06 446 SUPERFAMILY SSF49464 128 204 2.35E-7 T 31-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily DFR85_09905 35f8bb9e93186274094d56b26aa89c06 446 Gene3D G3DSA:1.20.5.340 315 420 3.7E-6 T 31-10-2018 DFR85_09905 35f8bb9e93186274094d56b26aa89c06 446 Gene3D G3DSA:2.60.40.1120 127 197 1.3E-5 T 31-10-2018 DFR85_06655 6f77ee3c0e79c7ed8167bf4d9c05e18d 56 Gene3D G3DSA:2.20.28.70 1 56 1.5E-28 T 31-10-2018 IPR038587 Ribosomal protein L40e superfamily Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 DFR85_06655 6f77ee3c0e79c7ed8167bf4d9c05e18d 56 SMART SM01377 3 51 1.4E-20 T 31-10-2018 IPR001975 Ribosomal protein L40e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 DFR85_06655 6f77ee3c0e79c7ed8167bf4d9c05e18d 56 Pfam PF01020 Ribosomal L40e family 9 49 4.4E-8 T 31-10-2018 IPR001975 Ribosomal protein L40e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 DFR85_06655 6f77ee3c0e79c7ed8167bf4d9c05e18d 56 Hamap MF_00788 50S ribosomal protein L40e [rpl40e]. 7 52 16.373 T 31-10-2018 IPR023657 Ribosomal protein L40e, archaeal GO:0003735|GO:0005840|GO:0006412 DFR85_06655 6f77ee3c0e79c7ed8167bf4d9c05e18d 56 SUPERFAMILY SSF57829 1 55 1.56E-18 T 31-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 DFR85_03475 4a430e0d0d26f35b38dce635f71bbcc0 313 SUPERFAMILY SSF102114 13 278 1.19E-45 T 31-10-2018 DFR85_03475 4a430e0d0d26f35b38dce635f71bbcc0 313 PIRSF PIRSF037420 1 241 4.4E-42 T 31-10-2018 IPR017200 Coenzyme PQQ synthesis protein E DFR85_03475 4a430e0d0d26f35b38dce635f71bbcc0 313 PIRSF PIRSF037420 246 300 0.066 T 31-10-2018 IPR017200 Coenzyme PQQ synthesis protein E DFR85_03475 4a430e0d0d26f35b38dce635f71bbcc0 313 Pfam PF13353 4Fe-4S single cluster domain 14 120 1.5E-7 T 31-10-2018 DFR85_03475 4a430e0d0d26f35b38dce635f71bbcc0 313 Gene3D G3DSA:3.20.20.70 11 302 2.9E-42 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_03475 4a430e0d0d26f35b38dce635f71bbcc0 313 Pfam PF04055 Radical SAM superfamily 17 171 3.6E-16 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR85_07025 3734b90fb9ca59a32be374f18e8b6dd5 184 TIGRFAM TIGR03653 uL6_arch: ribosomal protein uL6 8 177 1.1E-61 T 31-10-2018 IPR019907 Ribosomal protein L6P, archaea GO:0003735|GO:0005840|GO:0006412|GO:0019843 DFR85_07025 3734b90fb9ca59a32be374f18e8b6dd5 184 SUPERFAMILY SSF56053 5 85 7.81E-14 T 31-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07025 3734b90fb9ca59a32be374f18e8b6dd5 184 PIRSF PIRSF002162 1 179 1.2E-29 T 31-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07025 3734b90fb9ca59a32be374f18e8b6dd5 184 Gene3D G3DSA:3.90.930.12 86 182 4.9E-32 T 31-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07025 3734b90fb9ca59a32be374f18e8b6dd5 184 Hamap MF_01365_A 50S ribosomal protein L6 [rplF]. 1 178 32.743 T 31-10-2018 IPR019907 Ribosomal protein L6P, archaea GO:0003735|GO:0005840|GO:0006412|GO:0019843 DFR85_07025 3734b90fb9ca59a32be374f18e8b6dd5 184 Pfam PF00347 Ribosomal protein L6 12 85 6.1E-10 T 31-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07025 3734b90fb9ca59a32be374f18e8b6dd5 184 Pfam PF00347 Ribosomal protein L6 97 171 1.1E-11 T 31-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07025 3734b90fb9ca59a32be374f18e8b6dd5 184 SUPERFAMILY SSF56053 86 177 2.88E-26 T 31-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07025 3734b90fb9ca59a32be374f18e8b6dd5 184 ProSitePatterns PS00700 Ribosomal protein L6 signature 2. 156 177 - T 31-10-2018 IPR002359 Ribosomal protein L6, conserved site-2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07025 3734b90fb9ca59a32be374f18e8b6dd5 184 Gene3D G3DSA:3.90.930.12 5 85 4.3E-18 T 31-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_09125 5949f9c4d6b61449e25cd69255b2f802 407 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 35 45 - T 31-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 DFR85_09125 5949f9c4d6b61449e25cd69255b2f802 407 Gene3D G3DSA:3.50.50.60 4 290 1.5E-63 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_09125 5949f9c4d6b61449e25cd69255b2f802 407 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 34 49 2.0E-30 T 31-10-2018 DFR85_09125 5949f9c4d6b61449e25cd69255b2f802 407 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 268 275 2.0E-30 T 31-10-2018 DFR85_09125 5949f9c4d6b61449e25cd69255b2f802 407 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 152 177 2.0E-30 T 31-10-2018 DFR85_09125 5949f9c4d6b61449e25cd69255b2f802 407 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 2.0E-30 T 31-10-2018 DFR85_09125 5949f9c4d6b61449e25cd69255b2f802 407 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 302 323 2.0E-30 T 31-10-2018 DFR85_09125 5949f9c4d6b61449e25cd69255b2f802 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 275 4.1E-27 T 31-10-2018 DFR85_09125 5949f9c4d6b61449e25cd69255b2f802 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 152 170 4.1E-27 T 31-10-2018 DFR85_09125 5949f9c4d6b61449e25cd69255b2f802 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 230 246 4.1E-27 T 31-10-2018 DFR85_09125 5949f9c4d6b61449e25cd69255b2f802 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 120 138 4.1E-27 T 31-10-2018 DFR85_09125 5949f9c4d6b61449e25cd69255b2f802 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 4.1E-27 T 31-10-2018 DFR85_09125 5949f9c4d6b61449e25cd69255b2f802 407 SUPERFAMILY SSF51905 3 296 1.13E-38 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_09125 5949f9c4d6b61449e25cd69255b2f802 407 Gene3D G3DSA:3.30.390.30 306 407 1.5E-18 T 31-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 DFR85_09125 5949f9c4d6b61449e25cd69255b2f802 407 SUPERFAMILY SSF55424 305 404 1.65E-18 T 31-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 DFR85_09125 5949f9c4d6b61449e25cd69255b2f802 407 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 306 401 5.8E-12 T 31-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 DFR85_09125 5949f9c4d6b61449e25cd69255b2f802 407 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 287 4.9E-44 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR85_09125 5949f9c4d6b61449e25cd69255b2f802 407 Gene3D G3DSA:3.50.50.60 132 237 1.5E-63 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_15760 e973b68fcec09e2ffc570ea7aa58f6ae 699 SMART SM00382 203 339 3.0E-23 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_15760 e973b68fcec09e2ffc570ea7aa58f6ae 699 SMART SM00382 463 600 4.1E-22 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_15760 e973b68fcec09e2ffc570ea7aa58f6ae 699 Gene3D G3DSA:1.10.8.60 599 674 2.0E-95 T 31-10-2018 DFR85_15760 e973b68fcec09e2ffc570ea7aa58f6ae 699 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 467 597 1.5E-46 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 DFR85_15760 e973b68fcec09e2ffc570ea7aa58f6ae 699 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 207 336 4.9E-48 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 DFR85_15760 e973b68fcec09e2ffc570ea7aa58f6ae 699 ProSitePatterns PS00674 AAA-protein family signature. 307 325 - T 31-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 DFR85_15760 e973b68fcec09e2ffc570ea7aa58f6ae 699 Gene3D G3DSA:3.40.50.300 427 688 2.0E-95 T 31-10-2018 DFR85_15760 e973b68fcec09e2ffc570ea7aa58f6ae 699 Gene3D G3DSA:3.40.50.300 155 337 1.6E-65 T 31-10-2018 DFR85_15760 e973b68fcec09e2ffc570ea7aa58f6ae 699 ProSitePatterns PS00674 AAA-protein family signature. 568 586 - T 31-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 DFR85_15760 e973b68fcec09e2ffc570ea7aa58f6ae 699 SUPERFAMILY SSF52540 425 690 3.81E-66 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_15760 e973b68fcec09e2ffc570ea7aa58f6ae 699 Gene3D G3DSA:1.10.8.60 338 426 8.8E-26 T 31-10-2018 DFR85_15760 e973b68fcec09e2ffc570ea7aa58f6ae 699 SUPERFAMILY SSF52540 165 416 7.58E-69 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_15760 e973b68fcec09e2ffc570ea7aa58f6ae 699 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 649 667 5.7E-5 T 31-10-2018 DFR85_15760 e973b68fcec09e2ffc570ea7aa58f6ae 699 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 211 230 5.7E-5 T 31-10-2018 DFR85_07725 8cc057bf1490567d37411a88cdbd3719 598 PRINTS PR00315 GTP-binding elongation factor signature 78 88 6.6E-10 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR85_07725 8cc057bf1490567d37411a88cdbd3719 598 PRINTS PR00315 GTP-binding elongation factor signature 12 25 6.6E-10 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR85_07725 8cc057bf1490567d37411a88cdbd3719 598 PRINTS PR00315 GTP-binding elongation factor signature 130 139 6.6E-10 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR85_07725 8cc057bf1490567d37411a88cdbd3719 598 PRINTS PR00315 GTP-binding elongation factor signature 94 105 6.6E-10 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR85_07725 8cc057bf1490567d37411a88cdbd3719 598 Hamap MF_00100_A Translation initiation factor IF-2 [infB]. 6 594 41.958 T 31-10-2018 IPR004544 Translation initiation factor aIF-2, archaea GO:0003743|GO:0005525|GO:0005622|GO:0006413 DFR85_07725 8cc057bf1490567d37411a88cdbd3719 598 Pfam PF00009 Elongation factor Tu GTP binding domain 12 219 9.3E-32 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR85_07725 8cc057bf1490567d37411a88cdbd3719 598 SUPERFAMILY SSF52156 337 458 2.75E-28 T 31-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily DFR85_07725 8cc057bf1490567d37411a88cdbd3719 598 Gene3D G3DSA:3.40.50.300 2 232 3.4E-63 T 31-10-2018 DFR85_07725 8cc057bf1490567d37411a88cdbd3719 598 Pfam PF03144 Elongation factor Tu domain 2 250 329 2.1E-9 T 31-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 DFR85_07725 8cc057bf1490567d37411a88cdbd3719 598 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 12 141 3.1E-18 T 31-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 DFR85_07725 8cc057bf1490567d37411a88cdbd3719 598 Pfam PF14578 Elongation factor Tu domain 4 466 551 4.1E-37 T 31-10-2018 IPR029459 Elongation factor Tu-type domain DFR85_07725 8cc057bf1490567d37411a88cdbd3719 598 Gene3D G3DSA:2.40.30.10 465 554 2.7E-32 T 31-10-2018 DFR85_07725 8cc057bf1490567d37411a88cdbd3719 598 TIGRFAM TIGR00491 aIF-2: translation initiation factor aIF-2 8 591 6.5E-243 T 31-10-2018 IPR004544 Translation initiation factor aIF-2, archaea GO:0003743|GO:0005525|GO:0005622|GO:0006413 DFR85_07725 8cc057bf1490567d37411a88cdbd3719 598 Pfam PF11987 Translation-initiation factor 2 346 445 1.3E-15 T 31-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 DFR85_07725 8cc057bf1490567d37411a88cdbd3719 598 SUPERFAMILY SSF52540 9 293 9.4E-50 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_07725 8cc057bf1490567d37411a88cdbd3719 598 SUPERFAMILY SSF50447 464 590 3.77E-27 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily DFR85_07725 8cc057bf1490567d37411a88cdbd3719 598 Gene3D G3DSA:3.40.50.10050 353 456 6.1E-26 T 31-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily DFR85_07725 8cc057bf1490567d37411a88cdbd3719 598 Gene3D G3DSA:2.40.30.10 235 352 1.5E-37 T 31-10-2018 DFR85_02135 0e62db275ed52c056f76aaa64a0ba127 413 Pfam PF00083 Sugar (and other) transporter 251 412 9.9E-8 T 31-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 DFR85_02135 0e62db275ed52c056f76aaa64a0ba127 413 Pfam PF00083 Sugar (and other) transporter 10 206 2.3E-17 T 31-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 DFR85_02135 0e62db275ed52c056f76aaa64a0ba127 413 Gene3D G3DSA:1.20.1250.20 4 413 9.3E-56 T 31-10-2018 DFR85_02135 0e62db275ed52c056f76aaa64a0ba127 413 ProSitePatterns PS00216 Sugar transport proteins signature 1. 284 300 - T 31-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DFR85_02135 0e62db275ed52c056f76aaa64a0ba127 413 SUPERFAMILY SSF103473 4 411 1.07E-50 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_09470 84e84ae658992743010f31defe74724f 946 Hamap MF_00049_A Leucine--tRNA ligase [leuS]. 9 946 16.432 T 31-10-2018 IPR020791 Leucine-tRNA ligase, archaeal GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4 DFR85_09470 84e84ae658992743010f31defe74724f 946 Pfam PF08264 Anticodon-binding domain of tRNA 698 831 1.9E-21 T 31-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 DFR85_09470 84e84ae658992743010f31defe74724f 946 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 15 666 7.4E-56 T 31-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR85_09470 84e84ae658992743010f31defe74724f 946 Gene3D G3DSA:3.40.50.620 13 664 6.1E-265 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR85_09470 84e84ae658992743010f31defe74724f 946 TIGRFAM TIGR00395 leuS_arch: leucine--tRNA ligase 12 946 1.2E-282 T 31-10-2018 IPR004493 Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 DFR85_09470 84e84ae658992743010f31defe74724f 946 SUPERFAMILY SSF52374 8 673 2.17E-96 T 31-10-2018 DFR85_09470 84e84ae658992743010f31defe74724f 946 SUPERFAMILY SSF47323 688 861 9.72E-29 T 31-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR85_09470 84e84ae658992743010f31defe74724f 946 SUPERFAMILY SSF50677 206 428 1.47E-33 T 31-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 DFR85_09470 84e84ae658992743010f31defe74724f 946 Gene3D G3DSA:3.30.2320.20 808 945 1.9E-15 T 31-10-2018 DFR85_09470 84e84ae658992743010f31defe74724f 946 Gene3D G3DSA:3.90.740.10 203 435 6.1E-265 T 31-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 DFR85_09470 84e84ae658992743010f31defe74724f 946 Gene3D G3DSA:1.10.10.720 837 894 1.9E-15 T 31-10-2018 DFR85_09470 84e84ae658992743010f31defe74724f 946 Gene3D G3DSA:1.10.730.10 672 782 5.2E-17 T 31-10-2018 DFR85_14490 d0b297987fb790ef709561dc84a030c3 293 PIRSF PIRSF006648 1 292 6.8E-88 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 DFR85_14490 d0b297987fb790ef709561dc84a030c3 293 Pfam PF01061 ABC-2 type transporter 18 258 4.3E-36 T 31-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 DFR85_14490 d0b297987fb790ef709561dc84a030c3 293 PRINTS PR00164 ABC-2 type transport system membrane protein signature 94 116 1.1E-8 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 DFR85_14490 d0b297987fb790ef709561dc84a030c3 293 PRINTS PR00164 ABC-2 type transport system membrane protein signature 216 235 1.1E-8 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 DFR85_14490 d0b297987fb790ef709561dc84a030c3 293 PRINTS PR00164 ABC-2 type transport system membrane protein signature 236 255 1.1E-8 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 DFR85_14490 d0b297987fb790ef709561dc84a030c3 293 PRINTS PR00164 ABC-2 type transport system membrane protein signature 141 166 1.1E-8 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 DFR85_00835 a09ba13370ea63766de4b052fd8a4604 521 SUPERFAMILY SSF52540 111 336 1.06E-30 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_00835 a09ba13370ea63766de4b052fd8a4604 521 Pfam PF03143 Elongation factor Tu C-terminal domain 434 519 2.8E-6 T 31-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal DFR85_00835 a09ba13370ea63766de4b052fd8a4604 521 SUPERFAMILY SSF50465 433 520 1.3E-18 T 31-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal DFR85_00835 a09ba13370ea63766de4b052fd8a4604 521 Pfam PF00009 Elongation factor Tu GTP binding domain 112 329 1.6E-21 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR85_00835 a09ba13370ea63766de4b052fd8a4604 521 Gene3D G3DSA:2.40.30.10 342 433 3.5E-18 T 31-10-2018 DFR85_00835 a09ba13370ea63766de4b052fd8a4604 521 Gene3D G3DSA:3.40.50.300 105 335 6.6E-34 T 31-10-2018 DFR85_00835 a09ba13370ea63766de4b052fd8a4604 521 Gene3D G3DSA:2.40.30.10 434 521 8.1E-8 T 31-10-2018 DFR85_00835 a09ba13370ea63766de4b052fd8a4604 521 SUPERFAMILY SSF50447 344 432 2.91E-15 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily DFR85_10430 70faa6943fe72ce27262d22795c7abb9 135 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 55 84 - T 31-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 DFR85_10430 70faa6943fe72ce27262d22795c7abb9 135 SUPERFAMILY SSF51230 11 133 1.57E-41 T 31-10-2018 IPR011053 Single hybrid motif DFR85_10430 70faa6943fe72ce27262d22795c7abb9 135 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 12 133 37.311 T 31-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 DFR85_10430 70faa6943fe72ce27262d22795c7abb9 135 Gene3D G3DSA:2.40.50.100 1 132 3.9E-50 T 31-10-2018 DFR85_10430 70faa6943fe72ce27262d22795c7abb9 135 Pfam PF01597 Glycine cleavage H-protein 15 132 1.4E-45 T 31-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate DFR85_10430 70faa6943fe72ce27262d22795c7abb9 135 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 14 132 3.1E-44 T 31-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 DFR85_10290 026c367dc67e6e2630ce6d012d56500e 199 Pfam PF00239 Resolvase, N terminal domain 59 183 1.0E-22 T 31-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 DFR85_10290 026c367dc67e6e2630ce6d012d56500e 199 ProSitePatterns PS00397 Site-specific recombinases active site. 62 70 - T 31-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 DFR85_10290 026c367dc67e6e2630ce6d012d56500e 199 SMART SM00857 59 185 2.2E-18 T 31-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 DFR85_10290 026c367dc67e6e2630ce6d012d56500e 199 Gene3D G3DSA:1.10.1660.10 2 55 9.8E-7 T 31-10-2018 DFR85_10290 026c367dc67e6e2630ce6d012d56500e 199 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 4 50 2.1E-9 T 31-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 DFR85_10290 026c367dc67e6e2630ce6d012d56500e 199 Pfam PF12728 Helix-turn-helix domain 4 51 3.7E-15 T 31-10-2018 DFR85_10290 026c367dc67e6e2630ce6d012d56500e 199 SUPERFAMILY SSF46955 3 50 4.21E-8 T 31-10-2018 IPR009061 Putative DNA-binding domain superfamily DFR85_10290 026c367dc67e6e2630ce6d012d56500e 199 Gene3D G3DSA:3.40.50.1390 56 155 3.8E-23 T 31-10-2018 DFR85_10290 026c367dc67e6e2630ce6d012d56500e 199 SUPERFAMILY SSF53041 58 183 9.42E-21 T 31-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 DFR85_10910 d3659713a43f0e1f74079baf6ac269b1 529 SMART SM00387 27 150 2.1E-5 T 31-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase DFR85_10910 d3659713a43f0e1f74079baf6ac269b1 529 SUPERFAMILY SSF55874 14 227 2.23E-38 T 31-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily DFR85_10910 d3659713a43f0e1f74079baf6ac269b1 529 Gene3D G3DSA:3.30.565.10 1 229 1.4E-68 T 31-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily DFR85_10910 d3659713a43f0e1f74079baf6ac269b1 529 SUPERFAMILY SSF54211 308 468 3.87E-63 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold DFR85_10910 d3659713a43f0e1f74079baf6ac269b1 529 SUPERFAMILY SSF46946 230 303 3.4E-16 T 31-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 DFR85_10910 d3659713a43f0e1f74079baf6ac269b1 529 Hamap MF_00322 Type 2 DNA topoisomerase 6 subunit B [top6B]. 4 509 29.121 T 31-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 DFR85_10910 d3659713a43f0e1f74079baf6ac269b1 529 Gene3D G3DSA:1.10.8.50 230 307 2.2E-30 T 31-10-2018 DFR85_10910 d3659713a43f0e1f74079baf6ac269b1 529 Pfam PF09239 Topoisomerase VI B subunit, transducer 309 467 1.4E-65 T 31-10-2018 IPR015320 DNA topoisomerase VI, subunit B, transducer GO:0003677|GO:0003918|GO:0006265 DFR85_10910 d3659713a43f0e1f74079baf6ac269b1 529 Gene3D G3DSA:3.30.230.10 308 529 1.0E-83 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup DFR85_10910 d3659713a43f0e1f74079baf6ac269b1 529 ProDom PD013790 TOPOISOMERASE ISOMERASE SUBUNIT DNA B VI TYPE II NUCLEOTIDE-BINDING ATP-BINDING 307 509 3.0E-72 T 31-10-2018 IPR015320 DNA topoisomerase VI, subunit B, transducer GO:0003677|GO:0003918|GO:0006265 DFR85_10910 d3659713a43f0e1f74079baf6ac269b1 529 TIGRFAM TIGR01052 top6b: DNA topoisomerase VI, B subunit 4 486 1.7E-168 T 31-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 DFR85_10910 d3659713a43f0e1f74079baf6ac269b1 529 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 33 151 4.7E-11 T 31-10-2018 DFR85_10910 d3659713a43f0e1f74079baf6ac269b1 529 PIRSF PIRSF006553 1 528 1.7E-198 T 31-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 DFR85_09570 9b0d9de65c0b905fb74446f24a443f19 480 Pfam PF09180 Prolyl-tRNA synthetase, C-terminal 415 480 1.6E-15 T 31-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 DFR85_09570 9b0d9de65c0b905fb74446f24a443f19 480 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 100 271 7.4E-25 T 31-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR85_09570 9b0d9de65c0b905fb74446f24a443f19 480 SUPERFAMILY SSF55681 10 277 1.15E-80 T 31-10-2018 DFR85_09570 9b0d9de65c0b905fb74446f24a443f19 480 SUPERFAMILY SSF52954 281 405 8.76E-29 T 31-10-2018 DFR85_09570 9b0d9de65c0b905fb74446f24a443f19 480 Hamap MF_01571 Proline--tRNA ligase [proS]. 5 480 39.66 T 31-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 DFR85_09570 9b0d9de65c0b905fb74446f24a443f19 480 SMART SM00946 414 480 1.6E-23 T 31-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 DFR85_09570 9b0d9de65c0b905fb74446f24a443f19 480 Gene3D G3DSA:3.30.930.10 3 282 1.9E-82 T 31-10-2018 DFR85_09570 9b0d9de65c0b905fb74446f24a443f19 480 TIGRFAM TIGR00408 proS_fam_I: proline--tRNA ligase 9 480 2.8E-174 T 31-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 DFR85_09570 9b0d9de65c0b905fb74446f24a443f19 480 PRINTS PR01046 Prolyl-tRNA synthetase signature 106 117 6.7E-11 T 31-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 DFR85_09570 9b0d9de65c0b905fb74446f24a443f19 480 PRINTS PR01046 Prolyl-tRNA synthetase signature 146 157 6.7E-11 T 31-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 DFR85_09570 9b0d9de65c0b905fb74446f24a443f19 480 PRINTS PR01046 Prolyl-tRNA synthetase signature 136 144 6.7E-11 T 31-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 DFR85_09570 9b0d9de65c0b905fb74446f24a443f19 480 PRINTS PR01046 Prolyl-tRNA synthetase signature 65 83 6.7E-11 T 31-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 DFR85_09570 9b0d9de65c0b905fb74446f24a443f19 480 Gene3D G3DSA:3.40.50.800 284 405 1.2E-35 T 31-10-2018 IPR036621 Anticodon-binding domain superfamily DFR85_09570 9b0d9de65c0b905fb74446f24a443f19 480 Pfam PF03129 Anticodon binding domain 290 387 3.9E-21 T 31-10-2018 IPR004154 Anticodon-binding DFR85_09570 9b0d9de65c0b905fb74446f24a443f19 480 Gene3D G3DSA:3.30.110.30 408 479 1.2E-16 T 31-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 DFR85_09570 9b0d9de65c0b905fb74446f24a443f19 480 SUPERFAMILY SSF64586 408 480 3.34E-18 T 31-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 DFR85_11945 442a8956134568a1516089ccb084530b 243 SUPERFAMILY SSF81301 16 49 3.48E-5 T 31-10-2018 DFR85_13320 b9952583cb9f211bd9fe3b8d5440ee10 595 Pfam PF09848 Uncharacterized conserved protein (DUF2075) 226 583 1.1E-65 T 31-10-2018 IPR018647 Domain of unknown function DUF2075 DFR85_13320 b9952583cb9f211bd9fe3b8d5440ee10 595 Gene3D G3DSA:3.40.50.300 173 391 7.1E-11 T 31-10-2018 DFR85_13320 b9952583cb9f211bd9fe3b8d5440ee10 595 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 228 241 - T 31-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 DFR85_13320 b9952583cb9f211bd9fe3b8d5440ee10 595 SUPERFAMILY SSF52540 202 583 9.8E-13 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_13320 b9952583cb9f211bd9fe3b8d5440ee10 595 SUPERFAMILY SSF52540 107 328 1.17E-16 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_05565 f54774566109dd201ae60e6efb34c9a6 203 Gene3D G3DSA:1.20.144.10 111 199 4.2E-19 T 31-10-2018 DFR85_05565 f54774566109dd201ae60e6efb34c9a6 203 SUPERFAMILY SSF48317 39 198 1.83E-42 T 31-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily DFR85_05565 f54774566109dd201ae60e6efb34c9a6 203 SMART SM00014 75 185 4.6E-17 T 31-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase DFR85_05565 f54774566109dd201ae60e6efb34c9a6 203 Pfam PF01569 PAP2 superfamily 78 189 1.2E-20 T 31-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase DFR85_01850 a000d1c198472f9a3296846ffa5ce014 183 Gene3D G3DSA:3.40.225.10 3 182 1.2E-56 T 31-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily DFR85_01850 a000d1c198472f9a3296846ffa5ce014 183 Pfam PF10120 Thiamine-phosphate synthase 14 176 2.0E-54 T 31-10-2018 IPR019293 Thiamine-phosphate synthase ThiN GO:0004789 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 DFR85_01850 a000d1c198472f9a3296846ffa5ce014 183 SUPERFAMILY SSF53639 6 179 2.43E-54 T 31-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily DFR85_06910 360e56348fad9613800ee3e2d749a8e4 175 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 21 163 2.7E-29 T 31-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 DFR85_06910 360e56348fad9613800ee3e2d749a8e4 175 Gene3D G3DSA:3.40.630.30 2 172 6.6E-52 T 31-10-2018 DFR85_06910 360e56348fad9613800ee3e2d749a8e4 175 SUPERFAMILY SSF55729 12 167 6.8E-33 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase DFR85_06910 360e56348fad9613800ee3e2d749a8e4 175 Pfam PF00583 Acetyltransferase (GNAT) family 44 144 6.2E-19 T 31-10-2018 IPR000182 GNAT domain DFR85_06410 91aa551499ddf11e1575949c1b1abe52 185 Gene3D G3DSA:3.30.2010.10 24 103 2.6E-8 T 31-10-2018 DFR85_06410 91aa551499ddf11e1575949c1b1abe52 185 Pfam PF01435 Peptidase family M48 48 185 9.9E-22 T 31-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 DFR85_09220 d6b22f7fefd549931b9aded54a655c10 280 Gene3D G3DSA:3.30.1490.20 102 170 8.9E-27 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 DFR85_09220 d6b22f7fefd549931b9aded54a655c10 280 SUPERFAMILY SSF52440 2 86 2.62E-21 T 31-10-2018 IPR016185 Pre-ATP-grasp domain superfamily DFR85_09220 d6b22f7fefd549931b9aded54a655c10 280 TIGRFAM TIGR02144 LysX_arch: lysine biosynthesis enzyme LysX 3 277 5.1E-107 T 31-10-2018 IPR011870 Lysine biosynthesis enzyme LysX GO:0003824|GO:0005524|GO:0009085 DFR85_09220 d6b22f7fefd549931b9aded54a655c10 280 SUPERFAMILY SSF56059 85 276 8.49E-39 T 31-10-2018 DFR85_09220 d6b22f7fefd549931b9aded54a655c10 280 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 3 275 1.5E-91 T 31-10-2018 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 Reactome: R-HSA-70614 DFR85_09220 d6b22f7fefd549931b9aded54a655c10 280 Pfam PF08443 RimK-like ATP-grasp domain 84 276 3.3E-30 T 31-10-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 DFR85_09220 d6b22f7fefd549931b9aded54a655c10 280 Gene3D G3DSA:3.30.470.20 171 280 1.4E-28 T 31-10-2018 DFR85_09220 d6b22f7fefd549931b9aded54a655c10 280 Gene3D G3DSA:3.40.50.20 1 101 8.2E-28 T 31-10-2018 DFR85_06400 334aa81344147bc96bc03486c008b6ee 155 PIRSF PIRSF005067 1 155 1.5E-33 T 31-10-2018 IPR016437 MCT-1/Tma20 DFR85_06400 334aa81344147bc96bc03486c008b6ee 155 SUPERFAMILY SSF88697 69 150 9.39E-16 T 31-10-2018 IPR015947 PUA-like superfamily DFR85_06400 334aa81344147bc96bc03486c008b6ee 155 SUPERFAMILY SSF88802 2 65 6.41E-19 T 31-10-2018 DFR85_06400 334aa81344147bc96bc03486c008b6ee 155 Pfam PF09183 Domain of unknown function (DUF1947) 2 63 3.0E-22 T 31-10-2018 IPR015266 Domain of unknown function DUF1947 DFR85_06400 334aa81344147bc96bc03486c008b6ee 155 Gene3D G3DSA:2.30.130.10 69 151 1.5E-19 T 31-10-2018 IPR036974 PUA domain superfamily GO:0003723 DFR85_06400 334aa81344147bc96bc03486c008b6ee 155 Pfam PF01472 PUA domain 70 140 5.3E-11 T 31-10-2018 IPR002478 PUA domain GO:0003723 DFR85_06400 334aa81344147bc96bc03486c008b6ee 155 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 51 145 4.3E-11 T 31-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 DFR85_06400 334aa81344147bc96bc03486c008b6ee 155 TIGRFAM TIGR03684 arCOG00985: arCOG04150 universal archaeal PUA-domain protein 3 150 5.8E-41 T 31-10-2018 IPR022430 Conserved hypothetical protein CHP03684 DFR85_06400 334aa81344147bc96bc03486c008b6ee 155 Gene3D G3DSA:3.10.450.120 1 65 6.8E-11 T 31-10-2018 DFR85_11595 1907f9061862078a8bbbda3f3ffd10ed 161 SUPERFAMILY SSF52540 1 124 6.96E-7 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_13355 cd89b1af2097ecdf202471277242b517 555 Pfam PF00069 Protein kinase domain 281 532 8.2E-32 T 31-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DFR85_13355 cd89b1af2097ecdf202471277242b517 555 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 287 308 - T 31-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 DFR85_13355 cd89b1af2097ecdf202471277242b517 555 SUPERFAMILY SSF56112 278 504 1.08E-42 T 31-10-2018 IPR011009 Protein kinase-like domain superfamily DFR85_13355 cd89b1af2097ecdf202471277242b517 555 SMART SM00220 281 548 1.7E-19 T 31-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DFR85_13355 cd89b1af2097ecdf202471277242b517 555 Gene3D G3DSA:1.10.510.10 265 550 1.2E-40 T 31-10-2018 DFR85_13355 cd89b1af2097ecdf202471277242b517 555 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 418 430 - T 31-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 DFR85_14875 d66e02c79a9f88cbb33763c49e78b3f1 459 SUPERFAMILY SSF55103 208 441 9.48E-60 T 31-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 DFR85_14875 d66e02c79a9f88cbb33763c49e78b3f1 459 Pfam PF02913 FAD linked oxidases, C-terminal domain 203 438 1.8E-53 T 31-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 DFR85_14875 d66e02c79a9f88cbb33763c49e78b3f1 459 Pfam PF01565 FAD binding domain 36 169 2.3E-28 T 31-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 DFR85_14875 d66e02c79a9f88cbb33763c49e78b3f1 459 SUPERFAMILY SSF56176 4 204 1.54E-48 T 31-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 DFR85_14875 d66e02c79a9f88cbb33763c49e78b3f1 459 Gene3D G3DSA:3.30.70.2740 318 399 3.1E-7 T 31-10-2018 DFR85_14875 d66e02c79a9f88cbb33763c49e78b3f1 459 Gene3D G3DSA:3.30.465.40 2 224 1.9E-39 T 31-10-2018 DFR85_14875 d66e02c79a9f88cbb33763c49e78b3f1 459 Gene3D G3DSA:1.10.45.10 400 440 3.9E-9 T 31-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 DFR85_11320 74179988473a6a6ae40f2b7e0121b896 411 Pfam PF01966 HD domain 50 160 8.2E-15 T 31-10-2018 IPR006674 HD domain DFR85_11320 74179988473a6a6ae40f2b7e0121b896 411 SMART SM00471 46 198 3.7E-12 T 31-10-2018 IPR003607 HD/PDEase domain DFR85_11320 74179988473a6a6ae40f2b7e0121b896 411 SUPERFAMILY SSF109604 1 385 2.16E-80 T 31-10-2018 DFR85_11320 74179988473a6a6ae40f2b7e0121b896 411 Gene3D G3DSA:1.10.3210.10 1 302 4.6E-82 T 31-10-2018 DFR85_02425 5d5abd6d1b93e529ccff2d35f7832fcc 124 SMART SM00748 7 114 2.4E-37 T 31-10-2018 IPR007842 HEPN domain DFR85_02425 5d5abd6d1b93e529ccff2d35f7832fcc 124 Pfam PF05168 HEPN domain 4 120 2.3E-31 T 31-10-2018 IPR007842 HEPN domain DFR85_02425 5d5abd6d1b93e529ccff2d35f7832fcc 124 SUPERFAMILY SSF81593 4 121 3.69E-33 T 31-10-2018 DFR85_02425 5d5abd6d1b93e529ccff2d35f7832fcc 124 Gene3D G3DSA:1.20.120.330 2 122 9.2E-33 T 31-10-2018 DFR85_06700 5a07d8ac6b7bcb6ddd781b30b754e21c 351 SMART SM00279 225 259 8.5E-13 T 31-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 DFR85_06700 5a07d8ac6b7bcb6ddd781b30b754e21c 351 SUPERFAMILY SSF88723 4 238 8.18E-65 T 31-10-2018 IPR029060 PIN-like domain superfamily DFR85_06700 5a07d8ac6b7bcb6ddd781b30b754e21c 351 SUPERFAMILY SSF47807 223 351 1.79E-28 T 31-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily DFR85_06700 5a07d8ac6b7bcb6ddd781b30b754e21c 351 SMART SM00484 142 223 3.0E-27 T 31-10-2018 IPR006086 XPG-I domain GO:0004518 DFR85_06700 5a07d8ac6b7bcb6ddd781b30b754e21c 351 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 23 37 1.1E-31 T 31-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 DFR85_06700 5a07d8ac6b7bcb6ddd781b30b754e21c 351 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 141 158 1.1E-31 T 31-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 DFR85_06700 5a07d8ac6b7bcb6ddd781b30b754e21c 351 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 228 243 1.1E-31 T 31-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 DFR85_06700 5a07d8ac6b7bcb6ddd781b30b754e21c 351 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 77 96 1.1E-31 T 31-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 DFR85_06700 5a07d8ac6b7bcb6ddd781b30b754e21c 351 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 162 182 1.1E-31 T 31-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 DFR85_06700 5a07d8ac6b7bcb6ddd781b30b754e21c 351 SMART SM00485 1 103 1.2E-46 T 31-10-2018 IPR006085 XPG N-terminal GO:0004518|GO:0006281 DFR85_06700 5a07d8ac6b7bcb6ddd781b30b754e21c 351 Pfam PF00867 XPG I-region 142 238 1.7E-24 T 31-10-2018 IPR006086 XPG-I domain GO:0004518 DFR85_06700 5a07d8ac6b7bcb6ddd781b30b754e21c 351 ProSitePatterns PS00841 XPG protein signature 1. 75 89 - T 31-10-2018 IPR019974 XPG conserved site GO:0016788 DFR85_06700 5a07d8ac6b7bcb6ddd781b30b754e21c 351 Pfam PF00752 XPG N-terminal domain 5 103 5.6E-22 T 31-10-2018 IPR006085 XPG N-terminal GO:0004518|GO:0006281 DFR85_06700 5a07d8ac6b7bcb6ddd781b30b754e21c 351 TIGRFAM TIGR03674 fen_arch: flap structure-specific endonuclease 1 351 1.9E-138 T 31-10-2018 IPR019973 Flap structure-specific endonuclease, archaea GO:0016788 DFR85_06700 5a07d8ac6b7bcb6ddd781b30b754e21c 351 SMART SM00475 24 310 2.8E-4 T 31-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 DFR85_06700 5a07d8ac6b7bcb6ddd781b30b754e21c 351 Hamap MF_00614 Flap endonuclease 1 [fen]. 1 351 135.785 T 31-10-2018 IPR023426 Flap endonuclease 1 GO:0016788 Reactome: R-HSA-110362|Reactome: R-HSA-162594|Reactome: R-HSA-174437|Reactome: R-HSA-5651801|Reactome: R-HSA-5685939|Reactome: R-HSA-69166 DFR85_12175 d35d038669dcc7a4f3130b52da0b0ee9 265 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 151 252 1.0E-30 T 31-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 DFR85_12175 d35d038669dcc7a4f3130b52da0b0ee9 265 SUPERFAMILY SSF48179 150 258 3.23E-30 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 DFR85_12175 d35d038669dcc7a4f3130b52da0b0ee9 265 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 92 1.5E-18 T 31-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal DFR85_12175 d35d038669dcc7a4f3130b52da0b0ee9 265 PIRSF PIRSF000193 1 258 4.6E-70 T 31-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 DFR85_12175 d35d038669dcc7a4f3130b52da0b0ee9 265 Gene3D G3DSA:1.10.3730.10 154 257 2.3E-30 T 31-10-2018 DFR85_12175 d35d038669dcc7a4f3130b52da0b0ee9 265 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 4 253 4.5E-78 T 31-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 DFR85_12175 d35d038669dcc7a4f3130b52da0b0ee9 265 Gene3D G3DSA:3.40.50.720 1 153 3.3E-41 T 31-10-2018 DFR85_12175 d35d038669dcc7a4f3130b52da0b0ee9 265 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 211 233 - T 31-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 DFR85_12175 d35d038669dcc7a4f3130b52da0b0ee9 265 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 2 255 24.301 T 31-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 DFR85_12175 d35d038669dcc7a4f3130b52da0b0ee9 265 SUPERFAMILY SSF51735 3 149 1.07E-24 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_13840 5bb9bac1fd1a98a1a3d9cafe864bfe6a 163 SUPERFAMILY SSF50249 10 152 9.59E-29 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR85_13840 5bb9bac1fd1a98a1a3d9cafe864bfe6a 163 Gene3D G3DSA:1.10.12.20 6 76 5.4E-27 T 31-10-2018 DFR85_13840 5bb9bac1fd1a98a1a3d9cafe864bfe6a 163 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 37 70 1.4E-10 T 31-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal DFR85_06375 94a6531cb38beacf8742dfdd4c6a8423 350 Pfam PF01321 Creatinase/Prolidase N-terminal domain 2 126 1.0E-14 T 31-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 DFR85_06375 94a6531cb38beacf8742dfdd4c6a8423 350 Gene3D G3DSA:3.90.230.10 127 350 3.5E-71 T 31-10-2018 DFR85_06375 94a6531cb38beacf8742dfdd4c6a8423 350 SUPERFAMILY SSF53092 2 124 7.85E-16 T 31-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal DFR85_06375 94a6531cb38beacf8742dfdd4c6a8423 350 Gene3D G3DSA:3.40.350.10 1 126 1.1E-22 T 31-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal DFR85_06375 94a6531cb38beacf8742dfdd4c6a8423 350 Pfam PF00557 Metallopeptidase family M24 133 334 7.6E-58 T 31-10-2018 IPR000994 Peptidase M24 DFR85_06375 94a6531cb38beacf8742dfdd4c6a8423 350 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 281 293 - T 31-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site DFR85_06375 94a6531cb38beacf8742dfdd4c6a8423 350 SUPERFAMILY SSF55920 125 349 3.66E-64 T 31-10-2018 IPR036005 Creatinase/aminopeptidase-like DFR85_09290 892d0795a093b7356e70fd9ff433fde8 235 Gene3D G3DSA:3.30.200.20 6 229 1.0E-77 T 31-10-2018 DFR85_09290 892d0795a093b7356e70fd9ff433fde8 235 Pfam PF01259 SAICAR synthetase 6 213 1.1E-52 T 31-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 DFR85_09290 892d0795a093b7356e70fd9ff433fde8 235 Gene3D G3DSA:3.30.470.20 83 219 1.0E-77 T 31-10-2018 DFR85_09290 892d0795a093b7356e70fd9ff433fde8 235 ProSitePatterns PS01057 SAICAR synthetase signature 1. 84 98 - T 31-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 DFR85_09290 892d0795a093b7356e70fd9ff433fde8 235 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 3 233 27.149 T 31-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 DFR85_09290 892d0795a093b7356e70fd9ff433fde8 235 SUPERFAMILY SSF56104 4 231 6.54E-68 T 31-10-2018 DFR85_01450 fc407f6ecadc415a80017d27cf34ef0b 258 Pfam PF04321 RmlD substrate binding domain 58 187 1.7E-18 T 31-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 DFR85_01450 fc407f6ecadc415a80017d27cf34ef0b 258 Gene3D G3DSA:3.90.25.10 139 208 2.2E-33 T 31-10-2018 DFR85_01450 fc407f6ecadc415a80017d27cf34ef0b 258 SUPERFAMILY SSF51735 32 234 2.78E-31 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_01450 fc407f6ecadc415a80017d27cf34ef0b 258 Gene3D G3DSA:3.40.50.720 33 191 2.2E-33 T 31-10-2018 DFR85_02980 b50f4d9872e21ce2d729438269052c1d 650 SUPERFAMILY SSF53850 56 642 6.33E-66 T 31-10-2018 DFR85_02980 b50f4d9872e21ce2d729438269052c1d 650 PIRSF PIRSF002741 11 647 2.2E-35 T 31-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 DFR85_02980 b50f4d9872e21ce2d729438269052c1d 650 Gene3D G3DSA:3.10.105.10 380 619 5.4E-42 T 31-10-2018 DFR85_02980 b50f4d9872e21ce2d729438269052c1d 650 Gene3D G3DSA:3.40.190.10 282 631 5.4E-42 T 31-10-2018 DFR85_02980 b50f4d9872e21ce2d729438269052c1d 650 Gene3D G3DSA:3.40.190.10 46 166 4.2E-11 T 31-10-2018 DFR85_02980 b50f4d9872e21ce2d729438269052c1d 650 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 96 556 1.0E-64 T 31-10-2018 IPR000914 Solute-binding protein family 5 domain DFR85_02980 b50f4d9872e21ce2d729438269052c1d 650 Gene3D G3DSA:3.90.76.10 218 281 5.4E-42 T 31-10-2018 DFR85_10435 3f1bf2051591bee0ae29a2a45466f925 348 Gene3D G3DSA:4.10.1250.10 224 260 4.5E-10 T 31-10-2018 DFR85_10435 3f1bf2051591bee0ae29a2a45466f925 348 Gene3D G3DSA:3.30.70.1400 51 134 1.4E-58 T 31-10-2018 DFR85_10435 3f1bf2051591bee0ae29a2a45466f925 348 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 249 340 2.4E-16 T 31-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 DFR85_10435 3f1bf2051591bee0ae29a2a45466f925 348 SUPERFAMILY SSF101790 258 347 5.07E-16 T 31-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal DFR85_10435 3f1bf2051591bee0ae29a2a45466f925 348 Pfam PF01571 Aminomethyltransferase folate-binding domain 8 242 3.6E-66 T 31-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain DFR85_10435 3f1bf2051591bee0ae29a2a45466f925 348 Gene3D G3DSA:3.30.1360.120 5 221 1.4E-58 T 31-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 DFR85_10435 3f1bf2051591bee0ae29a2a45466f925 348 PIRSF PIRSF006487 1 348 9.4E-70 T 31-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 DFR85_10435 3f1bf2051591bee0ae29a2a45466f925 348 SUPERFAMILY SSF103025 3 265 1.57E-62 T 31-10-2018 DFR85_10435 3f1bf2051591bee0ae29a2a45466f925 348 Gene3D G3DSA:2.40.30.110 264 347 8.9E-15 T 31-10-2018 DFR85_10435 3f1bf2051591bee0ae29a2a45466f925 348 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 3 347 5.8E-76 T 31-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 DFR85_01415 feb71ba9e76ddee161688dffaf45db5f 249 Pfam PF01513 ATP-NAD kinase 29 232 1.7E-18 T 31-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 DFR85_01415 feb71ba9e76ddee161688dffaf45db5f 249 SUPERFAMILY SSF111331 16 233 7.19E-38 T 31-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily DFR85_01415 feb71ba9e76ddee161688dffaf45db5f 249 Hamap MF_00361 NAD kinase [nadK]. 1 249 19.428 T 31-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 DFR85_01415 feb71ba9e76ddee161688dffaf45db5f 249 Gene3D G3DSA:2.60.200.30 96 225 7.0E-35 T 31-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 DFR85_01415 feb71ba9e76ddee161688dffaf45db5f 249 Gene3D G3DSA:3.40.50.10330 32 235 7.0E-35 T 31-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 DFR85_14615 a01336f89bb8da23e7c8b882e6ff3fc3 402 SUPERFAMILY SSF56645 9 252 1.83E-74 T 31-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 DFR85_14615 a01336f89bb8da23e7c8b882e6ff3fc3 402 SUPERFAMILY SSF47203 240 394 3.7E-49 T 31-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 DFR85_14615 a01336f89bb8da23e7c8b882e6ff3fc3 402 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 15 128 5.3E-29 T 31-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 DFR85_14615 a01336f89bb8da23e7c8b882e6ff3fc3 402 Gene3D G3DSA:1.20.140.10 247 398 9.4E-48 T 31-10-2018 DFR85_14615 a01336f89bb8da23e7c8b882e6ff3fc3 402 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 242 389 5.8E-41 T 31-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DFR85_14615 a01336f89bb8da23e7c8b882e6ff3fc3 402 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 134 229 1.5E-22 T 31-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 DFR85_14615 a01336f89bb8da23e7c8b882e6ff3fc3 402 Gene3D G3DSA:2.40.110.10 131 246 5.1E-39 T 31-10-2018 DFR85_14615 a01336f89bb8da23e7c8b882e6ff3fc3 402 PIRSF PIRSF016578 11 380 2.4E-23 T 31-10-2018 DFR85_14615 a01336f89bb8da23e7c8b882e6ff3fc3 402 Gene3D G3DSA:1.10.540.10 5 130 7.9E-34 T 31-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 DFR85_07140 08a3c9d85a36ee2f811dcc501ee4966c 736 Pfam PF00009 Elongation factor Tu GTP binding domain 19 259 1.9E-61 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR85_07140 08a3c9d85a36ee2f811dcc501ee4966c 736 Gene3D G3DSA:3.30.70.240 472 724 6.1E-86 T 31-10-2018 DFR85_07140 08a3c9d85a36ee2f811dcc501ee4966c 736 Gene3D G3DSA:3.30.230.10 478 727 6.1E-86 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup DFR85_07140 08a3c9d85a36ee2f811dcc501ee4966c 736 Gene3D G3DSA:3.30.70.870 394 471 4.9E-24 T 31-10-2018 DFR85_07140 08a3c9d85a36ee2f811dcc501ee4966c 736 Gene3D G3DSA:3.40.50.300 5 222 6.9E-72 T 31-10-2018 DFR85_07140 08a3c9d85a36ee2f811dcc501ee4966c 736 SUPERFAMILY SSF54980 393 469 6.12E-22 T 31-10-2018 IPR035647 EF-G domain III/V-like DFR85_07140 08a3c9d85a36ee2f811dcc501ee4966c 736 SUPERFAMILY SSF52540 7 264 1.8E-70 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_07140 08a3c9d85a36ee2f811dcc501ee4966c 736 Pfam PF14492 Elongation Factor G, domain II 392 465 3.1E-23 T 31-10-2018 DFR85_07140 08a3c9d85a36ee2f811dcc501ee4966c 736 SMART SM00838 627 714 8.5E-42 T 31-10-2018 IPR000640 Elongation factor EFG, domain V-like DFR85_07140 08a3c9d85a36ee2f811dcc501ee4966c 736 Pfam PF00679 Elongation factor G C-terminus 628 710 2.5E-21 T 31-10-2018 IPR000640 Elongation factor EFG, domain V-like DFR85_07140 08a3c9d85a36ee2f811dcc501ee4966c 736 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 21 153 1.1E-21 T 31-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 DFR85_07140 08a3c9d85a36ee2f811dcc501ee4966c 736 Gene3D G3DSA:2.40.30.10 261 379 1.6E-23 T 31-10-2018 DFR85_07140 08a3c9d85a36ee2f811dcc501ee4966c 736 SUPERFAMILY SSF54211 469 629 2.33E-52 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold DFR85_07140 08a3c9d85a36ee2f811dcc501ee4966c 736 Hamap MF_00054_A Elongation factor G [fusA]. 1 731 42.35 T 31-10-2018 IPR004543 Translation elongation factor EFG/EF2, archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 DFR85_07140 08a3c9d85a36ee2f811dcc501ee4966c 736 SUPERFAMILY SSF54980 630 720 7.67E-22 T 31-10-2018 IPR035647 EF-G domain III/V-like DFR85_07140 08a3c9d85a36ee2f811dcc501ee4966c 736 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 59 74 - T 31-10-2018 IPR031157 Tr-type G domain, conserved site DFR85_07140 08a3c9d85a36ee2f811dcc501ee4966c 736 SMART SM00889 511 625 8.7E-24 T 31-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 DFR85_07140 08a3c9d85a36ee2f811dcc501ee4966c 736 Pfam PF03764 Elongation factor G, domain IV 517 625 5.8E-31 T 31-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 DFR85_07140 08a3c9d85a36ee2f811dcc501ee4966c 736 PRINTS PR00315 GTP-binding elongation factor signature 22 35 2.4E-16 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR85_07140 08a3c9d85a36ee2f811dcc501ee4966c 736 PRINTS PR00315 GTP-binding elongation factor signature 106 117 2.4E-16 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR85_07140 08a3c9d85a36ee2f811dcc501ee4966c 736 PRINTS PR00315 GTP-binding elongation factor signature 142 151 2.4E-16 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR85_07140 08a3c9d85a36ee2f811dcc501ee4966c 736 PRINTS PR00315 GTP-binding elongation factor signature 90 100 2.4E-16 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR85_07140 08a3c9d85a36ee2f811dcc501ee4966c 736 PRINTS PR00315 GTP-binding elongation factor signature 66 74 2.4E-16 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR85_07140 08a3c9d85a36ee2f811dcc501ee4966c 736 TIGRFAM TIGR00490 aEF-2: translation elongation factor aEF-2 3 726 2.1E-278 T 31-10-2018 IPR004543 Translation elongation factor EFG/EF2, archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 DFR85_07140 08a3c9d85a36ee2f811dcc501ee4966c 736 Pfam PF03144 Elongation factor Tu domain 2 308 374 1.2E-12 T 31-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 DFR85_07140 08a3c9d85a36ee2f811dcc501ee4966c 736 SUPERFAMILY SSF50447 261 379 2.75E-30 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily DFR85_03715 6c37b1009d7f07652663337e44b41b82 279 Pfam PF00753 Metallo-beta-lactamase superfamily 30 81 6.3E-8 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR85_03715 6c37b1009d7f07652663337e44b41b82 279 SUPERFAMILY SSF56281 20 256 2.27E-23 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR85_03715 6c37b1009d7f07652663337e44b41b82 279 Gene3D G3DSA:3.60.15.10 1 279 1.8E-72 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR85_10825 e8e5fb5772e1103b6bc734f329b55e59 217 Pfam PF13412 Winged helix-turn-helix DNA-binding 14 50 2.1E-7 T 31-10-2018 DFR85_10825 e8e5fb5772e1103b6bc734f329b55e59 217 Gene3D G3DSA:2.40.30.30 84 217 5.5E-42 T 31-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 DFR85_10825 e8e5fb5772e1103b6bc734f329b55e59 217 SUPERFAMILY SSF46785 11 79 6.16E-12 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_10825 e8e5fb5772e1103b6bc734f329b55e59 217 Hamap MF_01285 Riboflavin kinase [ribK]. 87 215 28.165 T 31-10-2018 IPR023470 Riboflavin kinase, archaeal GO:0008531|GO:0009231 KEGG: 00740+2.7.1.161|MetaCyc: PWY-6167 DFR85_10825 e8e5fb5772e1103b6bc734f329b55e59 217 SUPERFAMILY SSF82114 86 214 3.14E-41 T 31-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 DFR85_10825 e8e5fb5772e1103b6bc734f329b55e59 217 Pfam PF01982 Domain of unknown function DUF120 93 214 5.0E-40 T 31-10-2018 IPR023602 Riboflavin kinase domain, CTP-dependent GO:0016773 KEGG: 00740+2.7.1.161|MetaCyc: PWY-6167 DFR85_10825 e8e5fb5772e1103b6bc734f329b55e59 217 Gene3D G3DSA:1.10.10.10 5 81 4.2E-16 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_03685 c324562ae388e7e03361d2968d446489 205 Gene3D G3DSA:1.10.3320.10 13 145 1.4E-52 T 31-10-2018 IPR023288 Pa2218-like domain superfamily DFR85_03685 c324562ae388e7e03361d2968d446489 205 SUPERFAMILY SSF143555 6 159 8.63E-38 T 31-10-2018 DFR85_03685 c324562ae388e7e03361d2968d446489 205 Pfam PF02663 FmdE, Molybdenum formylmethanofuran dehydrogenase operon 16 151 1.7E-28 T 31-10-2018 IPR003814 Formylmethanofuran dehydrogenase, subunit E domain DFR85_03685 c324562ae388e7e03361d2968d446489 205 Gene3D G3DSA:3.30.1330.20 23 154 1.4E-52 T 31-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 DFR85_08360 4ff206eb2d8f5b1f82bf18e594ec3960 148 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 16 142 5.1E-40 T 31-10-2018 IPR005247 YbhB/YbcL DFR85_08360 4ff206eb2d8f5b1f82bf18e594ec3960 148 Gene3D G3DSA:3.90.280.10 1 148 1.9E-50 T 31-10-2018 IPR036610 PEBP-like superfamily DFR85_08360 4ff206eb2d8f5b1f82bf18e594ec3960 148 Pfam PF01161 Phosphatidylethanolamine-binding protein 13 145 1.3E-34 T 31-10-2018 IPR008914 Phosphatidylethanolamine-binding protein DFR85_08360 4ff206eb2d8f5b1f82bf18e594ec3960 148 SUPERFAMILY SSF49777 5 147 1.83E-43 T 31-10-2018 IPR036610 PEBP-like superfamily DFR85_12980 346290d2af146865ca54d031e10b1569 139 Pfam PF05168 HEPN domain 9 131 1.2E-18 T 31-10-2018 IPR007842 HEPN domain DFR85_12980 346290d2af146865ca54d031e10b1569 139 SUPERFAMILY SSF81593 9 132 1.02E-18 T 31-10-2018 DFR85_12980 346290d2af146865ca54d031e10b1569 139 SMART SM00748 10 125 3.0E-15 T 31-10-2018 IPR007842 HEPN domain DFR85_12980 346290d2af146865ca54d031e10b1569 139 Gene3D G3DSA:1.20.120.330 5 134 5.4E-16 T 31-10-2018 DFR85_11450 5b600a9ffccdc98b2641d48b4573eeef 302 Pfam PF02754 Cysteine-rich domain 153 243 1.3E-10 T 31-10-2018 IPR004017 Cysteine-rich domain DFR85_11450 5b600a9ffccdc98b2641d48b4573eeef 302 Pfam PF02754 Cysteine-rich domain 7 89 1.9E-16 T 31-10-2018 IPR004017 Cysteine-rich domain DFR85_06600 2a13690f5c5ea4eaec2917adfbbfebb5 195 Pfam PF01380 SIS domain 37 134 3.7E-16 T 31-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 DFR85_06600 2a13690f5c5ea4eaec2917adfbbfebb5 195 TIGRFAM TIGR03127 RuMP_HxlB: 6-phospho 3-hexuloisomerase 2 194 3.3E-67 T 31-10-2018 IPR017552 3-hexulose-6-phosphate isomerase GO:0016853 DFR85_06600 2a13690f5c5ea4eaec2917adfbbfebb5 195 Gene3D G3DSA:3.40.50.10490 1 194 4.2E-51 T 31-10-2018 DFR85_06600 2a13690f5c5ea4eaec2917adfbbfebb5 195 SUPERFAMILY SSF53697 3 193 5.56E-36 T 31-10-2018 DFR85_03935 d58293eec6f02447dbc3325a46b5f578 390 SUPERFAMILY SSF51338 2 380 2.3E-5 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR85_03935 d58293eec6f02447dbc3325a46b5f578 390 SUPERFAMILY SSF51556 43 340 2.95E-70 T 31-10-2018 IPR032466 Metal-dependent hydrolase DFR85_03935 d58293eec6f02447dbc3325a46b5f578 390 Pfam PF01979 Amidohydrolase family 39 379 1.8E-42 T 31-10-2018 IPR006680 Amidohydrolase-related GO:0016787 DFR85_03935 d58293eec6f02447dbc3325a46b5f578 390 Gene3D G3DSA:2.30.40.10 5 378 1.5E-87 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR85_03935 d58293eec6f02447dbc3325a46b5f578 390 Gene3D G3DSA:3.20.20.140 44 340 1.5E-87 T 31-10-2018 DFR85_01625 4be259653e086d734d674ea48e368971 263 PRINTS PR00721 Stomatin signature 30 52 1.2E-55 T 31-10-2018 IPR001972 Stomatin family GO:0016020 DFR85_01625 4be259653e086d734d674ea48e368971 263 PRINTS PR00721 Stomatin signature 175 196 1.2E-55 T 31-10-2018 IPR001972 Stomatin family GO:0016020 DFR85_01625 4be259653e086d734d674ea48e368971 263 PRINTS PR00721 Stomatin signature 112 129 1.2E-55 T 31-10-2018 IPR001972 Stomatin family GO:0016020 DFR85_01625 4be259653e086d734d674ea48e368971 263 PRINTS PR00721 Stomatin signature 200 223 1.2E-55 T 31-10-2018 IPR001972 Stomatin family GO:0016020 DFR85_01625 4be259653e086d734d674ea48e368971 263 PRINTS PR00721 Stomatin signature 156 174 1.2E-55 T 31-10-2018 IPR001972 Stomatin family GO:0016020 DFR85_01625 4be259653e086d734d674ea48e368971 263 PRINTS PR00721 Stomatin signature 77 98 1.2E-55 T 31-10-2018 IPR001972 Stomatin family GO:0016020 DFR85_01625 4be259653e086d734d674ea48e368971 263 PRINTS PR00721 Stomatin signature 132 155 1.2E-55 T 31-10-2018 IPR001972 Stomatin family GO:0016020 DFR85_01625 4be259653e086d734d674ea48e368971 263 SMART SM00244 23 180 2.1E-61 T 31-10-2018 IPR001107 Band 7 domain DFR85_01625 4be259653e086d734d674ea48e368971 263 Pfam PF01145 SPFH domain / Band 7 family 27 196 1.0E-38 T 31-10-2018 IPR001107 Band 7 domain DFR85_01625 4be259653e086d734d674ea48e368971 263 Gene3D G3DSA:3.30.479.30 51 182 9.3E-49 T 31-10-2018 DFR85_01625 4be259653e086d734d674ea48e368971 263 SUPERFAMILY SSF117892 54 186 1.16E-41 T 31-10-2018 IPR036013 Band 7/SPFH domain superfamily DFR85_01500 3871058fdc4efb87a9a08c3888fc55bb 170 Pfam PF00293 NUDIX domain 32 141 4.0E-16 T 31-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 DFR85_01500 3871058fdc4efb87a9a08c3888fc55bb 170 Gene3D G3DSA:3.90.79.10 1 167 5.5E-50 T 31-10-2018 DFR85_01500 3871058fdc4efb87a9a08c3888fc55bb 170 SUPERFAMILY SSF55811 3 166 7.04E-47 T 31-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 DFR85_01500 3871058fdc4efb87a9a08c3888fc55bb 170 ProSitePatterns PS00893 Nudix box signature. 66 87 - T 31-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 DFR85_05605 21d27f3c86f6686a690aaaf9018844e6 188 Pfam PF00117 Glutamine amidotransferase class-I 5 183 5.5E-38 T 31-10-2018 IPR017926 Glutamine amidotransferase DFR85_05605 21d27f3c86f6686a690aaaf9018844e6 188 SUPERFAMILY SSF52317 2 187 5.66E-52 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like DFR85_05605 21d27f3c86f6686a690aaaf9018844e6 188 Gene3D G3DSA:3.40.50.880 1 188 4.8E-56 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like DFR85_05605 21d27f3c86f6686a690aaaf9018844e6 188 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 3 187 1.4E-59 T 31-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 DFR85_05605 21d27f3c86f6686a690aaaf9018844e6 188 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 1.3E-5 T 31-10-2018 DFR85_05605 21d27f3c86f6686a690aaaf9018844e6 188 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 42 56 1.3E-5 T 31-10-2018 DFR85_05605 21d27f3c86f6686a690aaaf9018844e6 188 Hamap MF_01510 GMP synthase [glutamine-hydrolyzing] subunit A [guaAA]. 2 188 38.966 T 31-10-2018 IPR023686 GMP synthase (glutamine-hydrolyzing) subunit A GO:0003922 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 DFR85_05605 21d27f3c86f6686a690aaaf9018844e6 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 5.1E-9 T 31-10-2018 DFR85_05605 21d27f3c86f6686a690aaaf9018844e6 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 162 175 5.1E-9 T 31-10-2018 DFR85_05605 21d27f3c86f6686a690aaaf9018844e6 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 45 54 5.1E-9 T 31-10-2018 DFR85_05605 21d27f3c86f6686a690aaaf9018844e6 188 PRINTS PR00097 Anthranilate synthase component II signature 45 54 1.1E-7 T 31-10-2018 DFR85_05605 21d27f3c86f6686a690aaaf9018844e6 188 PRINTS PR00097 Anthranilate synthase component II signature 162 175 1.1E-7 T 31-10-2018 DFR85_05605 21d27f3c86f6686a690aaaf9018844e6 188 PRINTS PR00097 Anthranilate synthase component II signature 74 85 1.1E-7 T 31-10-2018 DFR85_05685 272485924b97315fa8091de820f626b3 807 SMART SM00220 490 806 1.5E-16 T 31-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DFR85_05685 272485924b97315fa8091de820f626b3 807 SUPERFAMILY SSF56112 489 805 1.5E-38 T 31-10-2018 IPR011009 Protein kinase-like domain superfamily DFR85_05685 272485924b97315fa8091de820f626b3 807 Pfam PF00069 Protein kinase domain 490 803 1.0E-29 T 31-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DFR85_05685 272485924b97315fa8091de820f626b3 807 Gene3D G3DSA:3.30.200.20 484 575 2.8E-7 T 31-10-2018 DFR85_05685 272485924b97315fa8091de820f626b3 807 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 496 519 - T 31-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 DFR85_05685 272485924b97315fa8091de820f626b3 807 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 638 650 - T 31-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 DFR85_05685 272485924b97315fa8091de820f626b3 807 Gene3D G3DSA:1.10.510.10 581 806 2.8E-27 T 31-10-2018 DFR85_06780 216074bded8fb1b150f5b0b8f24e131a 219 Gene3D G3DSA:3.30.700.20 9 201 4.6E-80 T 31-10-2018 IPR027485 AMMECR1, N-terminal DFR85_06780 216074bded8fb1b150f5b0b8f24e131a 219 TIGRFAM TIGR00296 TIGR00296: uncharacterized protein, PH0010 family 8 203 1.0E-57 T 31-10-2018 IPR023473 AMMECR1 DFR85_06780 216074bded8fb1b150f5b0b8f24e131a 219 Gene3D G3DSA:3.30.1490.150 115 189 4.6E-80 T 31-10-2018 DFR85_06780 216074bded8fb1b150f5b0b8f24e131a 219 SUPERFAMILY SSF143447 5 203 8.37E-61 T 31-10-2018 IPR036071 AMMECR1 domain superfamily DFR85_06780 216074bded8fb1b150f5b0b8f24e131a 219 TIGRFAM TIGR04335 AmmeMemoSam_A: AmmeMemoRadiSam system protein A 16 193 2.5E-52 T 31-10-2018 IPR027623 AmmeMemoRadiSam system protein A DFR85_06780 216074bded8fb1b150f5b0b8f24e131a 219 Pfam PF01871 AMMECR1 18 192 2.9E-46 T 31-10-2018 IPR002733 AMMECR1 domain DFR85_06780 216074bded8fb1b150f5b0b8f24e131a 219 Hamap MF_00645 Protein . 10 191 34.196 T 31-10-2018 IPR023472 Uncharacterised protein family MJ0810 DFR85_14005 70b96d6df4e6efb9df52a7295f3d21fe 401 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 255 330 7.2E-15 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR85_14005 70b96d6df4e6efb9df52a7295f3d21fe 401 Pfam PF01385 Probable transposase 181 287 5.9E-20 T 31-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 DFR85_14005 70b96d6df4e6efb9df52a7295f3d21fe 401 Pfam PF07282 Putative transposase DNA-binding domain 305 372 4.5E-23 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR85_05905 e8b3277e9de5fdae39621cfafe8fa569 124 SUPERFAMILY SSF54637 6 120 6.45E-40 T 31-10-2018 IPR029069 HotDog domain superfamily DFR85_05905 e8b3277e9de5fdae39621cfafe8fa569 124 PIRSF PIRSF014972 3 124 7.7E-40 T 31-10-2018 IPR025540 Fluoroacetyl-CoA thioesterase DFR85_05905 e8b3277e9de5fdae39621cfafe8fa569 124 Pfam PF03061 Thioesterase superfamily 29 95 1.2E-4 T 31-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 DFR85_05905 e8b3277e9de5fdae39621cfafe8fa569 124 Gene3D G3DSA:3.10.129.10 2 124 8.9E-41 T 31-10-2018 DFR85_02805 1efa5c6addcd08673ec2b6f1478443d2 346 Gene3D G3DSA:3.40.50.1970 2 158 2.3E-30 T 31-10-2018 DFR85_02805 1efa5c6addcd08673ec2b6f1478443d2 346 Gene3D G3DSA:1.20.1090.10 161 346 9.9E-43 T 31-10-2018 DFR85_02805 1efa5c6addcd08673ec2b6f1478443d2 346 SUPERFAMILY SSF56796 4 326 2.62E-49 T 31-10-2018 DFR85_02805 1efa5c6addcd08673ec2b6f1478443d2 346 Pfam PF13685 Iron-containing alcohol dehydrogenase 13 270 3.2E-42 T 31-10-2018 IPR032837 Glycerol-1-phosphate dehydrogenase KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 DFR85_01515 c3dd101af93be32dd0043d2f388e677b 221 SMART SM00987 48 211 2.2E-25 T 31-10-2018 DFR85_01515 c3dd101af93be32dd0043d2f388e677b 221 Pfam PF03167 Uracil DNA glycosylase superfamily 48 204 1.1E-31 T 31-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 DFR85_01515 c3dd101af93be32dd0043d2f388e677b 221 SMART SM00986 48 211 2.2E-25 T 31-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 DFR85_01515 c3dd101af93be32dd0043d2f388e677b 221 SUPERFAMILY SSF52141 16 216 3.05E-45 T 31-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 DFR85_01515 c3dd101af93be32dd0043d2f388e677b 221 Gene3D G3DSA:3.40.470.10 4 219 2.5E-62 T 31-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 DFR85_00055 61464bce6eadf77f282a7676312fc0a5 549 SUPERFAMILY SSF52518 349 540 6.1E-55 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR85_00055 61464bce6eadf77f282a7676312fc0a5 549 Gene3D G3DSA:3.40.50.970 1 173 4.3E-55 T 31-10-2018 DFR85_00055 61464bce6eadf77f282a7676312fc0a5 549 Gene3D G3DSA:3.40.50.970 339 549 1.9E-59 T 31-10-2018 DFR85_00055 61464bce6eadf77f282a7676312fc0a5 549 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 185 311 5.8E-30 T 31-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 DFR85_00055 61464bce6eadf77f282a7676312fc0a5 549 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 371 515 3.7E-39 T 31-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 DFR85_00055 61464bce6eadf77f282a7676312fc0a5 549 SUPERFAMILY SSF52467 185 355 3.45E-37 T 31-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily DFR85_00055 61464bce6eadf77f282a7676312fc0a5 549 Gene3D G3DSA:3.40.50.1220 177 327 5.8E-38 T 31-10-2018 DFR85_00055 61464bce6eadf77f282a7676312fc0a5 549 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 167 4.0E-44 T 31-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 DFR85_00055 61464bce6eadf77f282a7676312fc0a5 549 SUPERFAMILY SSF52518 3 170 2.36E-45 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR85_04675 5ff83238cfaa9dcba752150eb6ca020c 332 Gene3D G3DSA:1.10.10.10 262 328 3.0E-9 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_04675 5ff83238cfaa9dcba752150eb6ca020c 332 SUPERFAMILY SSF52540 7 258 1.78E-29 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_04675 5ff83238cfaa9dcba752150eb6ca020c 332 SUPERFAMILY SSF46785 264 328 1.14E-7 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_04675 5ff83238cfaa9dcba752150eb6ca020c 332 Gene3D G3DSA:3.40.50.300 5 184 7.2E-23 T 31-10-2018 DFR85_04675 5ff83238cfaa9dcba752150eb6ca020c 332 Pfam PF01637 ATPase domain predominantly from Archaea 18 219 2.1E-8 T 31-10-2018 IPR011579 ATPase domain GO:0005524 DFR85_04675 5ff83238cfaa9dcba752150eb6ca020c 332 Gene3D G3DSA:1.10.8.60 185 261 3.3E-16 T 31-10-2018 DFR85_10710 4b3de69491cf8b2d49260791ac6bd0bc 620 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 5 620 1.3E-108 T 31-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 DFR85_10710 4b3de69491cf8b2d49260791ac6bd0bc 620 SUPERFAMILY SSF52374 100 496 2.63E-71 T 31-10-2018 DFR85_10710 4b3de69491cf8b2d49260791ac6bd0bc 620 Pfam PF05746 DALR anticodon binding domain 504 620 2.1E-29 T 31-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 DFR85_10710 4b3de69491cf8b2d49260791ac6bd0bc 620 SUPERFAMILY SSF47323 498 620 3.86E-28 T 31-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR85_10710 4b3de69491cf8b2d49260791ac6bd0bc 620 Hamap MF_00123 Arginine--tRNA ligase [argS]. 2 620 22.363 T 31-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 DFR85_10710 4b3de69491cf8b2d49260791ac6bd0bc 620 SMART SM00836 504 620 1.5E-31 T 31-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 DFR85_10710 4b3de69491cf8b2d49260791ac6bd0bc 620 SUPERFAMILY SSF55190 2 95 3.01E-11 T 31-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 DFR85_10710 4b3de69491cf8b2d49260791ac6bd0bc 620 Gene3D G3DSA:1.10.730.10 504 620 1.4E-29 T 31-10-2018 DFR85_10710 4b3de69491cf8b2d49260791ac6bd0bc 620 PRINTS PR01038 Arginyl-tRNA synthetase signature 119 135 1.7E-13 T 31-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 DFR85_10710 4b3de69491cf8b2d49260791ac6bd0bc 620 PRINTS PR01038 Arginyl-tRNA synthetase signature 143 156 1.7E-13 T 31-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 DFR85_10710 4b3de69491cf8b2d49260791ac6bd0bc 620 PRINTS PR01038 Arginyl-tRNA synthetase signature 104 119 1.7E-13 T 31-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 DFR85_10710 4b3de69491cf8b2d49260791ac6bd0bc 620 Gene3D G3DSA:3.30.1360.70 1 95 2.1E-9 T 31-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 DFR85_10710 4b3de69491cf8b2d49260791ac6bd0bc 620 Gene3D G3DSA:3.40.50.620 102 503 2.4E-88 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR85_10710 4b3de69491cf8b2d49260791ac6bd0bc 620 Pfam PF00750 tRNA synthetases class I (R) 221 476 1.4E-17 T 31-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 DFR85_10710 4b3de69491cf8b2d49260791ac6bd0bc 620 Pfam PF00750 tRNA synthetases class I (R) 93 166 1.1E-14 T 31-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 DFR85_07450 f54076fdd3f814b42692c83c53fd0675 383 ProDom PD014260 DIHYDROOROTATE DEHYDROGENASE THERMOPHILE-SPECIFIC TA1428 ST0318 BLL2851 16-BISPHOSPHATASE APE1109 PF0613 MJ0299 1 363 0.0 T 31-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 DFR85_07450 f54076fdd3f814b42692c83c53fd0675 383 Pfam PF01950 Fructose-1,6-bisphosphatase 2 362 3.1E-181 T 31-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 DFR85_07450 f54076fdd3f814b42692c83c53fd0675 383 Hamap MF_02067 Fructose-1,6-bisphosphate aldolase/phosphatase [fbp]. 1 362 59.943 T 31-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 DFR85_07450 f54076fdd3f814b42692c83c53fd0675 383 SUPERFAMILY SSF111249 2 362 3.79E-172 T 31-10-2018 IPR036076 Fructose-1,6-bisphosphatase, class V superfamily KEGG: 00010+3.1.3.11+4.1.2.13|KEGG: 00030+3.1.3.11+4.1.2.13|KEGG: 00051+3.1.3.11+4.1.2.13|KEGG: 00680+3.1.3.11+4.1.2.13|KEGG: 00710+3.1.3.11+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 DFR85_07450 f54076fdd3f814b42692c83c53fd0675 383 PIRSF PIRSF015647 1 373 1.9E-185 T 31-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 DFR85_09435 72c508f07a003d1e493a97ef5d99b0f4 394 Gene3D G3DSA:3.40.50.1980 216 316 4.4E-97 T 31-10-2018 DFR85_09435 72c508f07a003d1e493a97ef5d99b0f4 394 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 21 392 5.9E-129 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 DFR85_09435 72c508f07a003d1e493a97ef5d99b0f4 394 Pfam PF00815 Histidinol dehydrogenase 16 392 1.6E-129 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 DFR85_09435 72c508f07a003d1e493a97ef5d99b0f4 394 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 212 244 - T 31-10-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 DFR85_09435 72c508f07a003d1e493a97ef5d99b0f4 394 PRINTS PR00083 Histidinol dehydrogenase signature 234 253 2.2E-83 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 DFR85_09435 72c508f07a003d1e493a97ef5d99b0f4 394 PRINTS PR00083 Histidinol dehydrogenase signature 328 346 2.2E-83 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 DFR85_09435 72c508f07a003d1e493a97ef5d99b0f4 394 PRINTS PR00083 Histidinol dehydrogenase signature 288 313 2.2E-83 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 DFR85_09435 72c508f07a003d1e493a97ef5d99b0f4 394 PRINTS PR00083 Histidinol dehydrogenase signature 212 233 2.2E-83 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 DFR85_09435 72c508f07a003d1e493a97ef5d99b0f4 394 PRINTS PR00083 Histidinol dehydrogenase signature 121 147 2.2E-83 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 DFR85_09435 72c508f07a003d1e493a97ef5d99b0f4 394 PRINTS PR00083 Histidinol dehydrogenase signature 153 179 2.2E-83 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 DFR85_09435 72c508f07a003d1e493a97ef5d99b0f4 394 PRINTS PR00083 Histidinol dehydrogenase signature 183 208 2.2E-83 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 DFR85_09435 72c508f07a003d1e493a97ef5d99b0f4 394 PRINTS PR00083 Histidinol dehydrogenase signature 21 45 2.2E-83 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 DFR85_09435 72c508f07a003d1e493a97ef5d99b0f4 394 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 2 393 36.113 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 DFR85_09435 72c508f07a003d1e493a97ef5d99b0f4 394 PIRSF PIRSF000099 4 394 2.1E-132 T 31-10-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 DFR85_09435 72c508f07a003d1e493a97ef5d99b0f4 394 Gene3D G3DSA:3.40.50.1980 19 215 4.4E-97 T 31-10-2018 DFR85_09435 72c508f07a003d1e493a97ef5d99b0f4 394 SUPERFAMILY SSF53720 17 360 1.33E-56 T 31-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 DFR85_11880 31872317de90d6f909f8220098795739 357 Gene3D G3DSA:3.40.50.410 38 204 1.5E-20 T 31-10-2018 IPR036465 von Willebrand factor A-like domain superfamily DFR85_11880 31872317de90d6f909f8220098795739 357 Pfam PF00092 von Willebrand factor type A domain 42 197 1.2E-11 T 31-10-2018 IPR002035 von Willebrand factor, type A DFR85_11880 31872317de90d6f909f8220098795739 357 SMART SM00327 38 200 8.8E-12 T 31-10-2018 IPR002035 von Willebrand factor, type A DFR85_11880 31872317de90d6f909f8220098795739 357 SUPERFAMILY SSF53300 40 198 2.64E-21 T 31-10-2018 IPR036465 von Willebrand factor A-like domain superfamily DFR85_15380 973f6b7edd39b23c72ff1d0374492a18 247 Gene3D G3DSA:1.10.12.10 190 247 5.3E-17 T 31-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal DFR85_15380 973f6b7edd39b23c72ff1d0374492a18 247 SUPERFAMILY SSF52096 2 246 9.7E-60 T 31-10-2018 IPR029045 ClpP/crotonase-like domain superfamily DFR85_15380 973f6b7edd39b23c72ff1d0374492a18 247 Gene3D G3DSA:3.90.226.10 1 187 2.3E-44 T 31-10-2018 DFR85_15380 973f6b7edd39b23c72ff1d0374492a18 247 Pfam PF00378 Enoyl-CoA hydratase/isomerase 7 246 8.7E-46 T 31-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 DFR85_04185 d10c3445a0d97eb46a7dc28a2d1f8a9a 685 Gene3D G3DSA:1.50.10.10 364 673 1.6E-27 T 31-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 DFR85_04185 d10c3445a0d97eb46a7dc28a2d1f8a9a 685 SUPERFAMILY SSF48208 358 670 1.81E-33 T 31-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 DFR85_04185 d10c3445a0d97eb46a7dc28a2d1f8a9a 685 Pfam PF12215 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term 13 290 2.3E-21 T 31-10-2018 IPR024462 Glycosyl-hydrolase family 116, N-terminal KEGG: 00511+3.2.1.45|KEGG: 00600+3.2.1.45|Reactome: R-HSA-1660662 DFR85_04185 d10c3445a0d97eb46a7dc28a2d1f8a9a 685 Pfam PF04685 Glycosyl-hydrolase family 116, catalytic region 333 651 7.4E-64 T 31-10-2018 IPR006775 Glycosyl-hydrolase family 116, catalytic region GO:0004553 KEGG: 00511+3.2.1.45|KEGG: 00600+3.2.1.45|Reactome: R-HSA-1660662 DFR85_05680 e367e66133144147caac58a5aaedff8e 386 Pfam PF07690 Major Facilitator Superfamily 17 342 5.1E-19 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_05680 e367e66133144147caac58a5aaedff8e 386 SUPERFAMILY SSF103473 3 384 1.01E-35 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_05680 e367e66133144147caac58a5aaedff8e 386 Gene3D G3DSA:1.20.1250.20 206 386 7.9E-9 T 31-10-2018 DFR85_05680 e367e66133144147caac58a5aaedff8e 386 Gene3D G3DSA:1.20.1250.20 1 194 5.3E-17 T 31-10-2018 DFR85_07130 b5a3d644c25b6e052bce62a6ebcf0754 474 Pfam PF04389 Peptidase family M28 185 335 5.3E-9 T 31-10-2018 IPR007484 Peptidase M28 DFR85_07130 b5a3d644c25b6e052bce62a6ebcf0754 474 Gene3D G3DSA:3.40.630.10 150 357 4.8E-19 T 31-10-2018 DFR85_07130 b5a3d644c25b6e052bce62a6ebcf0754 474 SUPERFAMILY SSF53187 5 336 1.92E-22 T 31-10-2018 DFR85_08335 55f5154fccc8d92250b5bbcf9987b2fb 412 SUPERFAMILY SSF52540 18 291 4.33E-35 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_08335 55f5154fccc8d92250b5bbcf9987b2fb 412 Gene3D G3DSA:1.10.10.10 302 412 7.4E-24 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_08335 55f5154fccc8d92250b5bbcf9987b2fb 412 SUPERFAMILY SSF46785 302 407 1.06E-25 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_08335 55f5154fccc8d92250b5bbcf9987b2fb 412 SMART SM01074 315 399 5.4E-24 T 31-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 DFR85_08335 55f5154fccc8d92250b5bbcf9987b2fb 412 TIGRFAM TIGR02928 TIGR02928: orc1/cdc6 family replication initiation protein 17 387 2.2E-102 T 31-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea DFR85_08335 55f5154fccc8d92250b5bbcf9987b2fb 412 Pfam PF09079 CDC6, C terminal winged helix domain 320 390 3.0E-17 T 31-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 DFR85_08335 55f5154fccc8d92250b5bbcf9987b2fb 412 Hamap MF_01407 ORC1-type DNA replication protein. 10 398 25.966 T 31-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea DFR85_08335 55f5154fccc8d92250b5bbcf9987b2fb 412 Gene3D G3DSA:1.10.8.60 17 295 2.1E-70 T 31-10-2018 DFR85_08335 55f5154fccc8d92250b5bbcf9987b2fb 412 Pfam PF13401 AAA domain 62 179 7.2E-11 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_08335 55f5154fccc8d92250b5bbcf9987b2fb 412 Gene3D G3DSA:3.40.50.300 33 214 2.1E-70 T 31-10-2018 DFR85_06825 4850f462d3664abc5a5f22ea8cbce927 531 Gene3D G3DSA:3.40.50.880 287 531 1.8E-103 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like DFR85_06825 4850f462d3664abc5a5f22ea8cbce927 531 Pfam PF06418 CTP synthase N-terminus 3 267 2.4E-121 T 31-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 DFR85_06825 4850f462d3664abc5a5f22ea8cbce927 531 Hamap MF_01227 CTP synthase [pyrG]. 2 531 49.782 T 31-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 DFR85_06825 4850f462d3664abc5a5f22ea8cbce927 531 SUPERFAMILY SSF52317 289 529 3.06E-74 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like DFR85_06825 4850f462d3664abc5a5f22ea8cbce927 531 Gene3D G3DSA:3.40.50.300 1 286 2.9E-131 T 31-10-2018 DFR85_06825 4850f462d3664abc5a5f22ea8cbce927 531 SUPERFAMILY SSF52540 1 269 1.2E-116 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_06825 4850f462d3664abc5a5f22ea8cbce927 531 TIGRFAM TIGR00337 PyrG: CTP synthase 2 527 2.2E-234 T 31-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 DFR85_06825 4850f462d3664abc5a5f22ea8cbce927 531 Pfam PF00117 Glutamine amidotransferase class-I 302 526 4.5E-53 T 31-10-2018 IPR017926 Glutamine amidotransferase DFR85_08175 f9319ea4742d933edcbb276a666c2ad3 75 Gene3D G3DSA:1.10.10.10 1 74 3.0E-6 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_08175 f9319ea4742d933edcbb276a666c2ad3 75 SUPERFAMILY SSF46785 4 67 2.41E-5 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_11645 f3a85970324ceb950b2e6835ddb6ff14 360 Gene3D G3DSA:3.90.180.10 16 357 5.9E-114 T 31-10-2018 DFR85_11645 f3a85970324ceb950b2e6835ddb6ff14 360 Hamap MF_02127 Glucose 1-dehydrogenase [gdh]. 1 360 61.587 T 31-10-2018 IPR026583 Glucose 1-dehydrogenase GO:0005536|GO:0008270|GO:0047936 KEGG: 00030+1.1.1.47 DFR85_11645 f3a85970324ceb950b2e6835ddb6ff14 360 SUPERFAMILY SSF50129 1 161 2.43E-37 T 31-10-2018 IPR011032 GroES-like superfamily DFR85_11645 f3a85970324ceb950b2e6835ddb6ff14 360 Pfam PF16912 Glucose dehydrogenase C-terminus 147 358 4.2E-32 T 31-10-2018 IPR031640 Glucose dehydrogenase, C-terminal KEGG: 00030+1.1.1.47 DFR85_11645 f3a85970324ceb950b2e6835ddb6ff14 360 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 65 79 - T 31-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 DFR85_11645 f3a85970324ceb950b2e6835ddb6ff14 360 Gene3D G3DSA:3.40.50.720 149 332 5.9E-114 T 31-10-2018 DFR85_11645 f3a85970324ceb950b2e6835ddb6ff14 360 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 139 5.1E-25 T 31-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DFR85_11645 f3a85970324ceb950b2e6835ddb6ff14 360 SUPERFAMILY SSF51735 183 316 5.81E-12 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_11815 c98bd5de7ba803be79495f3a88845020 147 Pfam PF01597 Glycine cleavage H-protein 14 135 8.6E-42 T 31-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate DFR85_11815 c98bd5de7ba803be79495f3a88845020 147 Gene3D G3DSA:2.40.50.100 7 136 1.9E-38 T 31-10-2018 DFR85_11815 c98bd5de7ba803be79495f3a88845020 147 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 56 85 - T 31-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 DFR85_11815 c98bd5de7ba803be79495f3a88845020 147 SUPERFAMILY SSF51230 19 135 1.12E-34 T 31-10-2018 IPR011053 Single hybrid motif DFR85_11815 c98bd5de7ba803be79495f3a88845020 147 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 10 138 34.919 T 31-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 DFR85_06555 a964fc6e53e5ecf0a521fa77de8f4fdd 387 PIRSF PIRSF000521 156 380 2.4E-34 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DFR85_06555 a964fc6e53e5ecf0a521fa77de8f4fdd 387 PIRSF PIRSF000521 11 116 1.2E-7 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DFR85_06555 a964fc6e53e5ecf0a521fa77de8f4fdd 387 PIRSF PIRSF000521 109 141 0.0044 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DFR85_06555 a964fc6e53e5ecf0a521fa77de8f4fdd 387 SUPERFAMILY SSF53383 6 378 8.11E-114 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase DFR85_06555 a964fc6e53e5ecf0a521fa77de8f4fdd 387 Hamap MF_02084 [LysW]-aminoadipate semialdehyde/glutamate semialdehyde transaminase [lysJ]. 4 378 48.785 T 31-10-2018 IPR037537 [LysW]-aminoadipate semialdehyde/glutamate semialdehyde transaminase GO:0008483 DFR85_06555 a964fc6e53e5ecf0a521fa77de8f4fdd 387 Pfam PF00202 Aminotransferase class-III 12 373 5.8E-105 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DFR85_06555 a964fc6e53e5ecf0a521fa77de8f4fdd 387 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 204 241 - T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DFR85_06555 a964fc6e53e5ecf0a521fa77de8f4fdd 387 Gene3D G3DSA:3.90.1150.10 13 371 8.7E-129 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 DFR85_06555 a964fc6e53e5ecf0a521fa77de8f4fdd 387 Gene3D G3DSA:3.40.640.10 46 286 8.7E-129 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR85_06555 a964fc6e53e5ecf0a521fa77de8f4fdd 387 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 4 375 1.8E-126 T 31-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 DFR85_03705 6442d96db56f4df8b67754ad97363018 87 Pfam PF03824 High-affinity nickel-transport protein 1 73 1.3E-14 T 31-10-2018 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 DFR85_15230 f0e840d2cc5a7375198baf67aabbfa77 159 Gene3D G3DSA:3.10.20.30 1 77 6.6E-29 T 31-10-2018 IPR012675 Beta-grasp domain superfamily DFR85_15230 f0e840d2cc5a7375198baf67aabbfa77 159 SUPERFAMILY SSF54292 4 81 7.21E-24 T 31-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 DFR85_15230 f0e840d2cc5a7375198baf67aabbfa77 159 Pfam PF01799 [2Fe-2S] binding domain 76 149 1.5E-32 T 31-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 DFR85_15230 f0e840d2cc5a7375198baf67aabbfa77 159 SUPERFAMILY SSF47741 87 157 4.97E-34 T 31-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily DFR85_15230 f0e840d2cc5a7375198baf67aabbfa77 159 Gene3D G3DSA:1.10.150.120 78 159 1.2E-35 T 31-10-2018 DFR85_15230 f0e840d2cc5a7375198baf67aabbfa77 159 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 8 64 1.6E-4 T 31-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 DFR85_12160 f7dfea44b24fd08d67a74e42b6e4ab72 252 SUPERFAMILY SSF52540 1 196 4.37E-23 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_12160 f7dfea44b24fd08d67a74e42b6e4ab72 252 Gene3D G3DSA:3.40.50.300 1 249 3.4E-23 T 31-10-2018 DFR85_12160 f7dfea44b24fd08d67a74e42b6e4ab72 252 Pfam PF13614 AAA domain 3 126 2.1E-10 T 31-10-2018 IPR025669 AAA domain DFR85_12545 f2172b5292d5eb1296236f3103eab18f 627 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 3 611 1.2E-183 T 31-10-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 DFR85_12545 f2172b5292d5eb1296236f3103eab18f 627 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 241 488 2.5E-61 T 31-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 DFR85_12545 f2172b5292d5eb1296236f3103eab18f 627 Gene3D G3DSA:3.40.920.10 1 218 1.7E-11 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 DFR85_12545 f2172b5292d5eb1296236f3103eab18f 627 SUPERFAMILY SSF52922 511 621 7.07E-20 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 DFR85_12545 f2172b5292d5eb1296236f3103eab18f 627 Gene3D G3DSA:3.40.50.970 219 426 5.3E-71 T 31-10-2018 DFR85_12545 f2172b5292d5eb1296236f3103eab18f 627 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 12 208 1.1E-32 T 31-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 DFR85_12545 f2172b5292d5eb1296236f3103eab18f 627 SUPERFAMILY SSF52518 227 495 5.2E-62 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR85_12545 f2172b5292d5eb1296236f3103eab18f 627 Gene3D G3DSA:3.40.50.920 503 615 9.0E-28 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 DFR85_12545 f2172b5292d5eb1296236f3103eab18f 627 SUPERFAMILY SSF53323 2 249 9.68E-15 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 DFR85_12545 f2172b5292d5eb1296236f3103eab18f 627 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 514 605 8.8E-10 T 31-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II DFR85_08915 0869b6ae249bb3bf923beb9075c9e305 227 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 138 162 - T 31-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 DFR85_08915 0869b6ae249bb3bf923beb9075c9e305 227 Gene3D G3DSA:3.40.50.10490 34 227 2.8E-65 T 31-10-2018 DFR85_08915 0869b6ae249bb3bf923beb9075c9e305 227 Hamap MF_00291_A 30S ribosomal protein S2 [rpsB]. 27 225 48.475 T 31-10-2018 IPR023454 Ribosomal protein S2, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_08915 0869b6ae249bb3bf923beb9075c9e305 227 PRINTS PR00395 Ribosomal protein S2 signature 113 130 1.7E-24 T 31-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_08915 0869b6ae249bb3bf923beb9075c9e305 227 PRINTS PR00395 Ribosomal protein S2 signature 35 53 1.7E-24 T 31-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_08915 0869b6ae249bb3bf923beb9075c9e305 227 PRINTS PR00395 Ribosomal protein S2 signature 65 74 1.7E-24 T 31-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_08915 0869b6ae249bb3bf923beb9075c9e305 227 PRINTS PR00395 Ribosomal protein S2 signature 138 155 1.7E-24 T 31-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_08915 0869b6ae249bb3bf923beb9075c9e305 227 PRINTS PR00395 Ribosomal protein S2 signature 155 166 1.7E-24 T 31-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_08915 0869b6ae249bb3bf923beb9075c9e305 227 PRINTS PR00395 Ribosomal protein S2 signature 176 190 1.7E-24 T 31-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_08915 0869b6ae249bb3bf923beb9075c9e305 227 Pfam PF00318 Ribosomal protein S2 39 129 1.1E-10 T 31-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_08915 0869b6ae249bb3bf923beb9075c9e305 227 Pfam PF00318 Ribosomal protein S2 137 202 8.0E-15 T 31-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_08915 0869b6ae249bb3bf923beb9075c9e305 227 TIGRFAM TIGR01012 uS2_euk_arch: ribosomal protein uS2 31 224 5.2E-87 T 31-10-2018 IPR005707 Ribosomal protein S2, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_08915 0869b6ae249bb3bf923beb9075c9e305 227 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 35 46 - T 31-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 DFR85_08915 0869b6ae249bb3bf923beb9075c9e305 227 SUPERFAMILY SSF52313 31 219 2.49E-59 T 31-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily DFR85_10605 41d211708647734c84ffb1059a88ddd3 778 Gene3D G3DSA:3.50.30.10 345 451 3.9E-44 T 31-10-2018 DFR85_10605 41d211708647734c84ffb1059a88ddd3 778 SUPERFAMILY SSF56059 9 372 2.94E-98 T 31-10-2018 DFR85_10605 41d211708647734c84ffb1059a88ddd3 778 SUPERFAMILY SSF52009 341 448 2.09E-36 T 31-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 DFR85_10605 41d211708647734c84ffb1059a88ddd3 778 Gene3D G3DSA:3.30.470.20 189 344 9.0E-47 T 31-10-2018 DFR85_10605 41d211708647734c84ffb1059a88ddd3 778 Gene3D G3DSA:3.20.20.60 476 770 1.3E-92 T 31-10-2018 DFR85_10605 41d211708647734c84ffb1059a88ddd3 778 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 672 690 - T 31-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 DFR85_10605 41d211708647734c84ffb1059a88ddd3 778 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 467 769 1.4E-79 T 31-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 DFR85_10605 41d211708647734c84ffb1059a88ddd3 778 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 11 770 0.0 T 31-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 DFR85_10605 41d211708647734c84ffb1059a88ddd3 778 Gene3D G3DSA:3.30.1490.20 7 188 3.9E-63 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 DFR85_10605 41d211708647734c84ffb1059a88ddd3 778 PIRSF PIRSF000854 6 774 4.3E-254 T 31-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 DFR85_10605 41d211708647734c84ffb1059a88ddd3 778 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 402 413 - T 31-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 DFR85_10605 41d211708647734c84ffb1059a88ddd3 778 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 23 338 3.4E-113 T 31-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 DFR85_10605 41d211708647734c84ffb1059a88ddd3 778 Pfam PF00391 PEP-utilising enzyme, mobile domain 372 443 2.9E-27 T 31-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 DFR85_10605 41d211708647734c84ffb1059a88ddd3 778 SUPERFAMILY SSF51621 468 773 1.83E-93 T 31-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 DFR85_07985 07aa56ac4f06dcdbbaa1e24daa843ce5 241 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 19 83 3.6E-20 T 31-10-2018 IPR002831 Transcription regulator TrmB, N-terminal DFR85_07985 07aa56ac4f06dcdbbaa1e24daa843ce5 241 SUPERFAMILY SSF46785 5 105 4.91E-16 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_07985 07aa56ac4f06dcdbbaa1e24daa843ce5 241 Gene3D G3DSA:1.10.10.10 12 107 8.4E-23 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_07985 07aa56ac4f06dcdbbaa1e24daa843ce5 241 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 38 3.1E-5 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR85_07985 07aa56ac4f06dcdbbaa1e24daa843ce5 241 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 49 68 3.1E-5 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR85_07985 07aa56ac4f06dcdbbaa1e24daa843ce5 241 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 38 49 3.1E-5 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR85_10170 133e5dd3056b256b116814493b38f176 169 Gene3D G3DSA:2.10.260.30 3 69 8.8E-25 T 31-10-2018 DFR85_10170 133e5dd3056b256b116814493b38f176 169 SUPERFAMILY SSF54747 3 82 1.05E-21 T 31-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily DFR85_10170 133e5dd3056b256b116814493b38f176 169 SUPERFAMILY SSF46906 66 138 1.3E-18 T 31-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily DFR85_10170 133e5dd3056b256b116814493b38f176 169 Pfam PF03946 Ribosomal protein L11, N-terminal domain 6 61 6.6E-19 T 31-10-2018 IPR020784 Ribosomal protein L11, N-terminal DFR85_10170 133e5dd3056b256b116814493b38f176 169 Pfam PF00298 Ribosomal protein L11, RNA binding domain 71 137 1.4E-19 T 31-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 DFR85_10170 133e5dd3056b256b116814493b38f176 169 Gene3D G3DSA:1.10.10.250 73 163 6.4E-31 T 31-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily DFR85_10170 133e5dd3056b256b116814493b38f176 169 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 2 139 24.45 T 31-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 DFR85_10170 133e5dd3056b256b116814493b38f176 169 ProSitePatterns PS00359 Ribosomal protein L11 signature. 124 139 - T 31-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_10170 133e5dd3056b256b116814493b38f176 169 SMART SM00649 6 138 1.6E-53 T 31-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 DFR85_02825 00eb4b1d9b01136e27f64e96eb85c1cf 466 SUPERFAMILY SSF50022 29 173 2.1E-40 T 31-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 DFR85_02825 00eb4b1d9b01136e27f64e96eb85c1cf 466 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 178 260 5.6E-6 T 31-10-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0044237|GO:0051537|GO:0055114 DFR85_02825 00eb4b1d9b01136e27f64e96eb85c1cf 466 SUPERFAMILY SSF55961 174 405 1.18E-33 T 31-10-2018 DFR85_02825 00eb4b1d9b01136e27f64e96eb85c1cf 466 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 102 125 - T 31-10-2018 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0051537|GO:0055114 DFR85_02825 00eb4b1d9b01136e27f64e96eb85c1cf 466 Pfam PF00355 Rieske [2Fe-2S] domain 59 141 9.3E-16 T 31-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DFR85_02825 00eb4b1d9b01136e27f64e96eb85c1cf 466 Gene3D G3DSA:2.102.10.10 58 182 4.2E-104 T 31-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 DFR85_02825 00eb4b1d9b01136e27f64e96eb85c1cf 466 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 43 68 8.7E-30 T 31-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 DFR85_02825 00eb4b1d9b01136e27f64e96eb85c1cf 466 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 198 220 8.7E-30 T 31-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 DFR85_02825 00eb4b1d9b01136e27f64e96eb85c1cf 466 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 116 136 8.7E-30 T 31-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 DFR85_02825 00eb4b1d9b01136e27f64e96eb85c1cf 466 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 158 184 8.7E-30 T 31-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 DFR85_02825 00eb4b1d9b01136e27f64e96eb85c1cf 466 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 95 115 8.7E-30 T 31-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 DFR85_02825 00eb4b1d9b01136e27f64e96eb85c1cf 466 Gene3D G3DSA:3.90.380.10 42 460 4.2E-104 T 31-10-2018 DFR85_05910 34059f7f6fca8e8711d2e2149fc74960 649 SUPERFAMILY SSF52540 11 334 6.47E-52 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_05910 34059f7f6fca8e8711d2e2149fc74960 649 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 104 113 - T 31-10-2018 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site DFR85_05910 34059f7f6fca8e8711d2e2149fc74960 649 SMART SM00490 227 322 4.5E-20 T 31-10-2018 IPR001650 Helicase, C-terminal DFR85_05910 34059f7f6fca8e8711d2e2149fc74960 649 SMART SM00487 2 168 8.7E-12 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain DFR85_05910 34059f7f6fca8e8711d2e2149fc74960 649 Pfam PF00270 DEAD/DEAH box helicase 12 147 3.5E-16 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 DFR85_05910 34059f7f6fca8e8711d2e2149fc74960 649 Gene3D G3DSA:3.40.50.300 3 163 2.2E-38 T 31-10-2018 DFR85_05910 34059f7f6fca8e8711d2e2149fc74960 649 Gene3D G3DSA:3.40.50.300 195 346 1.6E-28 T 31-10-2018 DFR85_05910 34059f7f6fca8e8711d2e2149fc74960 649 Pfam PF00271 Helicase conserved C-terminal domain 202 320 4.1E-16 T 31-10-2018 IPR001650 Helicase, C-terminal DFR85_13080 15ca55936796908fcb40dbb8342f1b0b 413 SUPERFAMILY SSF109604 2 372 7.54E-68 T 31-10-2018 DFR85_13080 15ca55936796908fcb40dbb8342f1b0b 413 Gene3D G3DSA:1.10.3210.10 1 301 2.6E-66 T 31-10-2018 DFR85_13080 15ca55936796908fcb40dbb8342f1b0b 413 Pfam PF01966 HD domain 48 184 1.2E-10 T 31-10-2018 IPR006674 HD domain DFR85_13080 15ca55936796908fcb40dbb8342f1b0b 413 SMART SM00471 44 191 4.9E-8 T 31-10-2018 IPR003607 HD/PDEase domain DFR85_10755 22eb24743c463c1f9a3cc67941cee9c2 233 Gene3D G3DSA:3.30.200.20 1 55 1.4E-26 T 31-10-2018 DFR85_10755 22eb24743c463c1f9a3cc67941cee9c2 233 SMART SM01206 8 233 3.7E-142 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 DFR85_10755 22eb24743c463c1f9a3cc67941cee9c2 233 PIRSF PIRSF006540 1 233 1.4E-98 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 DFR85_10755 22eb24743c463c1f9a3cc67941cee9c2 233 Hamap MF_00351 Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase [flpA]. 21 232 43.408 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 DFR85_10755 22eb24743c463c1f9a3cc67941cee9c2 233 Pfam PF01269 Fibrillarin 10 232 1.5E-100 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 DFR85_10755 22eb24743c463c1f9a3cc67941cee9c2 233 PRINTS PR00052 Fibrillarin signature 78 99 2.4E-70 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 DFR85_10755 22eb24743c463c1f9a3cc67941cee9c2 233 PRINTS PR00052 Fibrillarin signature 28 47 2.4E-70 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 DFR85_10755 22eb24743c463c1f9a3cc67941cee9c2 233 PRINTS PR00052 Fibrillarin signature 103 120 2.4E-70 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 DFR85_10755 22eb24743c463c1f9a3cc67941cee9c2 233 PRINTS PR00052 Fibrillarin signature 128 157 2.4E-70 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 DFR85_10755 22eb24743c463c1f9a3cc67941cee9c2 233 PRINTS PR00052 Fibrillarin signature 158 187 2.4E-70 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 DFR85_10755 22eb24743c463c1f9a3cc67941cee9c2 233 PRINTS PR00052 Fibrillarin signature 51 70 2.4E-70 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 DFR85_10755 22eb24743c463c1f9a3cc67941cee9c2 233 PRINTS PR00052 Fibrillarin signature 210 231 2.4E-70 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 DFR85_10755 22eb24743c463c1f9a3cc67941cee9c2 233 Gene3D G3DSA:3.40.50.150 56 233 3.1E-71 T 31-10-2018 DFR85_10755 22eb24743c463c1f9a3cc67941cee9c2 233 ProSitePatterns PS00566 Fibrillarin signature. 103 117 - T 31-10-2018 IPR020813 Fibrillarin, conserved site GO:0003723|GO:0006364|GO:0008168 DFR85_10755 22eb24743c463c1f9a3cc67941cee9c2 233 SUPERFAMILY SSF53335 11 230 1.63E-49 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR85_14975 461761e04350449dd9bcb5307175bc3c 561 SUPERFAMILY SSF56801 28 555 1.7E-144 T 31-10-2018 DFR85_14975 461761e04350449dd9bcb5307175bc3c 561 Pfam PF00501 AMP-binding enzyme 51 453 1.6E-82 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 DFR85_14975 461761e04350449dd9bcb5307175bc3c 561 Gene3D G3DSA:3.40.50.12780 16 446 2.6E-102 T 31-10-2018 DFR85_14975 461761e04350449dd9bcb5307175bc3c 561 Pfam PF13193 AMP-binding enzyme C-terminal domain 461 539 9.7E-24 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain DFR85_14975 461761e04350449dd9bcb5307175bc3c 561 ProSitePatterns PS00455 Putative AMP-binding domain signature. 206 217 - T 31-10-2018 IPR020845 AMP-binding, conserved site DFR85_14975 461761e04350449dd9bcb5307175bc3c 561 Gene3D G3DSA:3.30.300.30 448 561 8.1E-33 T 31-10-2018 DFR85_08545 7710e9203df773166226715b3b3e986f 615 Pfam PF13519 von Willebrand factor type A domain 444 548 2.0E-15 T 31-10-2018 IPR002035 von Willebrand factor, type A DFR85_08545 7710e9203df773166226715b3b3e986f 615 SMART SM00382 30 212 1.9E-7 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_08545 7710e9203df773166226715b3b3e986f 615 SUPERFAMILY SSF53300 442 600 1.51E-17 T 31-10-2018 IPR036465 von Willebrand factor A-like domain superfamily DFR85_08545 7710e9203df773166226715b3b3e986f 615 Gene3D G3DSA:3.40.50.410 436 609 1.2E-15 T 31-10-2018 IPR036465 von Willebrand factor A-like domain superfamily DFR85_08545 7710e9203df773166226715b3b3e986f 615 SUPERFAMILY SSF52540 8 325 1.43E-55 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_08545 7710e9203df773166226715b3b3e986f 615 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 251 312 2.5E-6 T 31-10-2018 IPR025158 Mg chelatase-related protein, C-terminal domain DFR85_08545 7710e9203df773166226715b3b3e986f 615 Gene3D G3DSA:1.10.8.80 254 341 2.6E-15 T 31-10-2018 DFR85_08545 7710e9203df773166226715b3b3e986f 615 Pfam PF01078 Magnesium chelatase, subunit ChlI 123 190 2.8E-7 T 31-10-2018 IPR000523 Magnesium chelatase ChlI domain DFR85_08545 7710e9203df773166226715b3b3e986f 615 SMART SM00327 441 612 3.7E-11 T 31-10-2018 IPR002035 von Willebrand factor, type A DFR85_08545 7710e9203df773166226715b3b3e986f 615 Gene3D G3DSA:3.40.50.300 4 208 1.1E-62 T 31-10-2018 DFR85_15300 ebebe1caea1f3a02178262d6e1b1432f 278 Pfam PF00753 Metallo-beta-lactamase superfamily 30 114 1.1E-9 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR85_15300 ebebe1caea1f3a02178262d6e1b1432f 278 SUPERFAMILY SSF56281 21 258 8.39E-27 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR85_15300 ebebe1caea1f3a02178262d6e1b1432f 278 SMART SM00849 28 250 0.0046 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR85_15300 ebebe1caea1f3a02178262d6e1b1432f 278 Gene3D G3DSA:3.60.15.10 1 277 5.9E-71 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR85_15200 5efadb5902108b8411034fe7bee4ceea 442 PIRSF PIRSF000521 142 437 7.4E-36 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DFR85_15200 5efadb5902108b8411034fe7bee4ceea 442 PIRSF PIRSF000521 2 147 1.2E-11 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DFR85_15200 5efadb5902108b8411034fe7bee4ceea 442 Gene3D G3DSA:3.40.640.10 81 333 2.6E-123 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR85_15200 5efadb5902108b8411034fe7bee4ceea 442 Pfam PF00202 Aminotransferase class-III 42 434 3.1E-101 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DFR85_15200 5efadb5902108b8411034fe7bee4ceea 442 SUPERFAMILY SSF53383 35 434 3.25E-111 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase DFR85_15200 5efadb5902108b8411034fe7bee4ceea 442 Gene3D G3DSA:3.90.1150.10 37 428 2.6E-123 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 DFR85_02445 f4c1e1c78eb4f65542893006fac5cf6c 85 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 63 74 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR85_02445 f4c1e1c78eb4f65542893006fac5cf6c 85 SUPERFAMILY SSF54862 10 83 1.03E-21 T 31-10-2018 DFR85_02445 f4c1e1c78eb4f65542893006fac5cf6c 85 Gene3D G3DSA:3.30.70.20 8 85 9.1E-14 T 31-10-2018 DFR85_02445 f4c1e1c78eb4f65542893006fac5cf6c 85 Pfam PF14697 4Fe-4S dicluster domain 27 80 1.1E-9 T 31-10-2018 DFR85_02445 f4c1e1c78eb4f65542893006fac5cf6c 85 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 9 83 2.9E-33 T 31-10-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 DFR85_02330 73a9b93c61207c3e00c39847bd26d459 81 Gene3D G3DSA:1.10.10.10 2 81 3.9E-11 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_02330 73a9b93c61207c3e00c39847bd26d459 81 SUPERFAMILY SSF46785 8 73 2.66E-11 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_02790 20196dc6395380ad417518f9bb5d7533 395 Gene3D G3DSA:3.20.20.140 38 335 8.2E-91 T 31-10-2018 DFR85_02790 20196dc6395380ad417518f9bb5d7533 395 SUPERFAMILY SSF51556 38 330 2.96E-61 T 31-10-2018 IPR032466 Metal-dependent hydrolase DFR85_02790 20196dc6395380ad417518f9bb5d7533 395 Pfam PF01979 Amidohydrolase family 33 302 2.4E-5 T 31-10-2018 IPR006680 Amidohydrolase-related GO:0016787 DFR85_02790 20196dc6395380ad417518f9bb5d7533 395 Gene3D G3DSA:2.30.40.10 21 375 8.2E-91 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR85_02790 20196dc6395380ad417518f9bb5d7533 395 SUPERFAMILY SSF51338 18 46 6.78E-5 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR85_07650 4af8c1093c2e7dcae70895007edbc65f 347 Pfam PF06973 Domain of unknown function (DUF1297) 159 347 4.3E-80 T 31-10-2018 IPR009720 IMP biosynthesis enzyme PurP, C-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 DFR85_07650 4af8c1093c2e7dcae70895007edbc65f 347 Pfam PF06849 Protein of unknown function (DUF1246) 3 127 1.1E-45 T 31-10-2018 IPR010672 IMP biosynthesis enzyme PurP, N-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 DFR85_07650 4af8c1093c2e7dcae70895007edbc65f 347 Gene3D G3DSA:3.30.470.20 95 345 3.0E-91 T 31-10-2018 DFR85_07650 4af8c1093c2e7dcae70895007edbc65f 347 Gene3D G3DSA:3.40.50.20 1 92 3.8E-30 T 31-10-2018 DFR85_07650 4af8c1093c2e7dcae70895007edbc65f 347 Gene3D G3DSA:3.30.1490.20 124 188 3.0E-91 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 DFR85_07650 4af8c1093c2e7dcae70895007edbc65f 347 PIRSF PIRSF004602 1 347 2.3E-141 T 31-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 DFR85_07650 4af8c1093c2e7dcae70895007edbc65f 347 SUPERFAMILY SSF52440 1 105 6.43E-37 T 31-10-2018 IPR016185 Pre-ATP-grasp domain superfamily DFR85_07650 4af8c1093c2e7dcae70895007edbc65f 347 SUPERFAMILY SSF56059 110 347 1.06E-74 T 31-10-2018 DFR85_05645 58ed0cc643e63a9e5393165190625148 247 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 246 1.5E-85 T 31-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 DFR85_05645 58ed0cc643e63a9e5393165190625148 247 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 239 5.7E-23 T 31-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase DFR85_05645 58ed0cc643e63a9e5393165190625148 247 SUPERFAMILY SSF56219 2 246 1.28E-74 T 31-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily DFR85_05645 58ed0cc643e63a9e5393165190625148 247 Gene3D G3DSA:3.60.10.10 1 247 1.5E-85 T 31-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily DFR85_05645 58ed0cc643e63a9e5393165190625148 247 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 2 246 1.9E-83 T 31-10-2018 DFR85_05645 58ed0cc643e63a9e5393165190625148 247 ProSitePatterns PS00728 AP endonucleases family 1 signature 3. 207 218 - T 31-10-2018 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 Reactome: R-HSA-110357|Reactome: R-HSA-110362|Reactome: R-HSA-110373|Reactome: R-HSA-5651801|Reactome: R-HSA-73930|Reactome: R-HSA-73933 DFR85_09720 cb6ee9ae8539acd733df71d4969adc3b 383 SUPERFAMILY SSF48208 209 315 1.62E-9 T 31-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 DFR85_09720 cb6ee9ae8539acd733df71d4969adc3b 383 Gene3D G3DSA:3.40.30.10 2 109 1.0E-6 T 31-10-2018 DFR85_06830 7ca9c4c7c75cea8f63f056b0cb563382 226 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 13 217 2.9E-18 T 31-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 DFR85_06830 7ca9c4c7c75cea8f63f056b0cb563382 226 SMART SM00934 14 217 2.0E-30 T 31-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 DFR85_06830 7ca9c4c7c75cea8f63f056b0cb563382 226 SUPERFAMILY SSF51366 14 222 1.44E-29 T 31-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 DFR85_06830 7ca9c4c7c75cea8f63f056b0cb563382 226 Gene3D G3DSA:3.20.20.70 13 225 5.5E-58 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_09270 ef521e90170448ddfc3ff934a2d84b8d 446 Pfam PF13537 Glutamine amidotransferase domain 81 190 2.2E-12 T 31-10-2018 IPR017932 Glutamine amidotransferase type 2 domain DFR85_09270 ef521e90170448ddfc3ff934a2d84b8d 446 SUPERFAMILY SSF56235 6 232 9.44E-50 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR85_09270 ef521e90170448ddfc3ff934a2d84b8d 446 SUPERFAMILY SSF53271 226 432 1.7E-58 T 31-10-2018 IPR029057 Phosphoribosyltransferase-like DFR85_09270 ef521e90170448ddfc3ff934a2d84b8d 446 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 6 430 1.6E-122 T 31-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 DFR85_09270 ef521e90170448ddfc3ff934a2d84b8d 446 PIRSF PIRSF000485 2 442 4.4E-155 T 31-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 DFR85_09270 ef521e90170448ddfc3ff934a2d84b8d 446 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 5 429 42.285 T 31-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 DFR85_09270 ef521e90170448ddfc3ff934a2d84b8d 446 Gene3D G3DSA:3.60.20.10 6 430 3.1E-134 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR85_09270 ef521e90170448ddfc3ff934a2d84b8d 446 Pfam PF00156 Phosphoribosyl transferase domain 256 361 5.7E-9 T 31-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 DFR85_09270 ef521e90170448ddfc3ff934a2d84b8d 446 Gene3D G3DSA:3.40.50.2020 250 414 3.1E-134 T 31-10-2018 DFR85_05875 5c8f2b236daadbdbf3e4953b7d0d0249 706 Gene3D G3DSA:1.10.150.20 646 701 1.3E-25 T 31-10-2018 DFR85_05875 5c8f2b236daadbdbf3e4953b7d0d0249 706 Gene3D G3DSA:1.10.3380.30 426 644 4.2E-64 T 31-10-2018 DFR85_05875 5c8f2b236daadbdbf3e4953b7d0d0249 706 SMART SM00487 23 211 1.9E-32 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain DFR85_05875 5c8f2b236daadbdbf3e4953b7d0d0249 706 SUPERFAMILY SSF52540 38 399 4.61E-53 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_05875 5c8f2b236daadbdbf3e4953b7d0d0249 706 SUPERFAMILY SSF158702 502 698 5.49E-60 T 31-10-2018 DFR85_05875 5c8f2b236daadbdbf3e4953b7d0d0249 706 Hamap MF_00442 ATP-dependent DNA helicase Hel308 [hel308]. 12 700 28.398 T 31-10-2018 IPR022965 ATP-dependent DNA helicase Hel308 GO:0004386 DFR85_05875 5c8f2b236daadbdbf3e4953b7d0d0249 706 Pfam PF00270 DEAD/DEAH box helicase 29 183 1.7E-26 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 DFR85_05875 5c8f2b236daadbdbf3e4953b7d0d0249 706 Pfam PF00271 Helicase conserved C-terminal domain 241 388 9.1E-10 T 31-10-2018 IPR001650 Helicase, C-terminal DFR85_05875 5c8f2b236daadbdbf3e4953b7d0d0249 706 Gene3D G3DSA:3.40.50.300 206 414 1.0E-56 T 31-10-2018 DFR85_05875 5c8f2b236daadbdbf3e4953b7d0d0249 706 Gene3D G3DSA:3.40.50.300 12 202 5.1E-73 T 31-10-2018 DFR85_05875 5c8f2b236daadbdbf3e4953b7d0d0249 706 SMART SM00490 299 388 4.4E-18 T 31-10-2018 IPR001650 Helicase, C-terminal DFR85_05875 5c8f2b236daadbdbf3e4953b7d0d0249 706 SUPERFAMILY SSF46785 419 501 8.34E-11 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_14485 cb3b7527c3abf558d98b329421fd4a3b 330 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DFR85_14485 cb3b7527c3abf558d98b329421fd4a3b 330 SMART SM00382 28 220 4.0E-9 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_14485 cb3b7527c3abf558d98b329421fd4a3b 330 Pfam PF13732 Domain of unknown function (DUF4162) 217 304 3.3E-14 T 31-10-2018 IPR025302 Domain of unknown function DUF4162 DFR85_14485 cb3b7527c3abf558d98b329421fd4a3b 330 Gene3D G3DSA:3.40.50.300 1 242 3.7E-69 T 31-10-2018 DFR85_14485 cb3b7527c3abf558d98b329421fd4a3b 330 SUPERFAMILY SSF52540 4 227 4.99E-67 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_14485 cb3b7527c3abf558d98b329421fd4a3b 330 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 11 305 4.7E-127 T 31-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 DFR85_14485 cb3b7527c3abf558d98b329421fd4a3b 330 Pfam PF00005 ABC transporter 20 162 3.5E-32 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR85_06260 e6c3b5652e7cfe52ff52585cb76413e5 730 SUPERFAMILY SSF52540 146 338 1.36E-11 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_06260 e6c3b5652e7cfe52ff52585cb76413e5 730 Gene3D G3DSA:3.40.630.30 382 581 2.7E-46 T 31-10-2018 DFR85_06260 e6c3b5652e7cfe52ff52585cb76413e5 730 SUPERFAMILY SSF55729 492 563 7.88E-9 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase DFR85_06260 e6c3b5652e7cfe52ff52585cb76413e5 730 Gene3D G3DSA:3.40.50.12320 212 381 6.4E-26 T 31-10-2018 DFR85_06260 e6c3b5652e7cfe52ff52585cb76413e5 730 Pfam PF05127 Helicase 217 391 8.4E-44 T 31-10-2018 IPR007807 Helicase domain Reactome: R-HSA-6790901 DFR85_06260 e6c3b5652e7cfe52ff52585cb76413e5 730 Pfam PF13718 GNAT acetyltransferase 2 421 530 2.8E-20 T 31-10-2018 IPR000182 GNAT domain DFR85_06260 e6c3b5652e7cfe52ff52585cb76413e5 730 Pfam PF13718 GNAT acetyltransferase 2 536 582 2.2E-7 T 31-10-2018 IPR000182 GNAT domain DFR85_06260 e6c3b5652e7cfe52ff52585cb76413e5 730 Hamap MF_01886 tRNA(Met) cytidine acetyltransferase TmcA [tmcA]. 14 721 38.574 T 31-10-2018 IPR024914 tRNA(Met) cytidine acetyltransferase TmcA GO:0000049|GO:0002101|GO:0051391|GO:0051392 DFR85_06260 e6c3b5652e7cfe52ff52585cb76413e5 730 Pfam PF08351 Domain of unknown function (DUF1726) 75 158 2.2E-20 T 31-10-2018 IPR013562 tRNA(Met) cytidine acetyltransferase TmcA, N-terminal Reactome: R-HSA-6790901 DFR85_10890 b5d1c57f2e87176a2e3fc50304639deb 929 Pfam PF00271 Helicase conserved C-terminal domain 240 335 3.9E-14 T 31-10-2018 IPR001650 Helicase, C-terminal DFR85_10890 b5d1c57f2e87176a2e3fc50304639deb 929 Gene3D G3DSA:3.40.50.300 211 366 1.4E-22 T 31-10-2018 DFR85_10890 b5d1c57f2e87176a2e3fc50304639deb 929 PIRSF PIRSF037307 1 929 3.3E-216 T 31-10-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 DFR85_10890 b5d1c57f2e87176a2e3fc50304639deb 929 SMART SM00490 256 335 7.5E-16 T 31-10-2018 IPR001650 Helicase, C-terminal DFR85_10890 b5d1c57f2e87176a2e3fc50304639deb 929 SMART SM00487 16 222 2.4E-34 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain DFR85_10890 b5d1c57f2e87176a2e3fc50304639deb 929 Gene3D G3DSA:3.40.50.300 2 206 8.9E-45 T 31-10-2018 DFR85_10890 b5d1c57f2e87176a2e3fc50304639deb 929 Pfam PF00270 DEAD/DEAH box helicase 21 192 1.1E-28 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 DFR85_10890 b5d1c57f2e87176a2e3fc50304639deb 929 SUPERFAMILY SSF52540 30 353 2.53E-46 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_10030 5a0223ab9a4e4f97fd742eaa79e5b977 344 Gene3D G3DSA:2.30.130.10 79 154 4.5E-6 T 31-10-2018 IPR036974 PUA domain superfamily GO:0003723 DFR85_10030 5a0223ab9a4e4f97fd742eaa79e5b977 344 Pfam PF01189 16S rRNA methyltransferase RsmB/F 172 315 4.2E-34 T 31-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 DFR85_10030 5a0223ab9a4e4f97fd742eaa79e5b977 344 Gene3D G3DSA:3.40.50.150 162 344 3.2E-45 T 31-10-2018 DFR85_10030 5a0223ab9a4e4f97fd742eaa79e5b977 344 SUPERFAMILY SSF88697 82 133 2.42E-6 T 31-10-2018 IPR015947 PUA-like superfamily DFR85_10030 5a0223ab9a4e4f97fd742eaa79e5b977 344 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 247 259 6.4E-21 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase DFR85_10030 5a0223ab9a4e4f97fd742eaa79e5b977 344 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 182 192 6.4E-21 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase DFR85_10030 5a0223ab9a4e4f97fd742eaa79e5b977 344 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 326 343 6.4E-21 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase DFR85_10030 5a0223ab9a4e4f97fd742eaa79e5b977 344 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 294 310 6.4E-21 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase DFR85_10030 5a0223ab9a4e4f97fd742eaa79e5b977 344 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 153 167 6.4E-21 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase DFR85_10030 5a0223ab9a4e4f97fd742eaa79e5b977 344 SUPERFAMILY SSF53335 4 344 6.39E-47 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR85_09360 c6179fd1b018776e8667133af0e057e9 155 Gene3D G3DSA:3.30.70.140 1 98 1.3E-37 T 31-10-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily DFR85_09360 c6179fd1b018776e8667133af0e057e9 155 Gene3D G3DSA:2.30.30.20 99 155 7.4E-22 T 31-10-2018 DFR85_09360 c6179fd1b018776e8667133af0e057e9 155 ProDom PD006194 REGULATORY ASPARTATE CARBAMOYLTRANSFERASE CHAIN METAL-BINDING ZINC PYRIMIDINE BIOSYNTHESIS SUBUNIT TRANSFERASE 7 96 2.0E-22 T 31-10-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal DFR85_09360 c6179fd1b018776e8667133af0e057e9 155 SUPERFAMILY SSF57825 101 153 1.23E-15 T 31-10-2018 IPR036792 Aspartate carbamoyltransferase regulatory subunit, C-terminal domain superfamily DFR85_09360 c6179fd1b018776e8667133af0e057e9 155 Hamap MF_00002 Aspartate carbamoyltransferase regulatory chain [pyrI]. 2 151 32.759 T 31-10-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 DFR85_09360 c6179fd1b018776e8667133af0e057e9 155 Pfam PF01948 Aspartate carbamoyltransferase regulatory chain, allosteric domain 6 96 1.1E-32 T 31-10-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal DFR85_09360 c6179fd1b018776e8667133af0e057e9 155 SUPERFAMILY SSF54893 2 99 5.1E-33 T 31-10-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily DFR85_09360 c6179fd1b018776e8667133af0e057e9 155 TIGRFAM TIGR00240 ATCase_reg: aspartate carbamoyltransferase, regulatory subunit 4 150 2.1E-52 T 31-10-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 DFR85_09360 c6179fd1b018776e8667133af0e057e9 155 Pfam PF02748 Aspartate carbamoyltransferase regulatory chain, metal binding domain 101 149 3.7E-16 T 31-10-2018 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal DFR85_07565 504beec211a3d7c9198e444af5bdc327 436 Gene3D G3DSA:3.90.600.20 156 250 4.9E-31 T 31-10-2018 DFR85_07565 504beec211a3d7c9198e444af5bdc327 436 Hamap MF_01892 tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS [tiaS]. 3 420 31.028 T 31-10-2018 IPR024913 tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS GO:0002101|GO:0016879 DFR85_07565 504beec211a3d7c9198e444af5bdc327 436 Gene3D G3DSA:3.30.70.2200 3 154 1.7E-42 T 31-10-2018 DFR85_07565 504beec211a3d7c9198e444af5bdc327 436 Pfam PF08489 Domain of unknown function (DUF1743) 142 253 1.4E-32 T 31-10-2018 IPR013696 Domain of unknown function DUF1743 DFR85_07565 504beec211a3d7c9198e444af5bdc327 436 Gene3D G3DSA:2.40.50.1010 251 396 2.3E-28 T 31-10-2018 DFR85_06755 b3f929ac7751c56c6968aab2daf5deb4 327 Gene3D G3DSA:3.60.15.10 7 165 1.4E-22 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR85_06755 b3f929ac7751c56c6968aab2daf5deb4 327 SUPERFAMILY SSF56281 26 322 2.03E-29 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR85_03725 9f988b47c56b9d1fd2a82c08c30a2721 321 SUPERFAMILY SSF54631 2 58 2.93E-8 T 31-10-2018 DFR85_03725 9f988b47c56b9d1fd2a82c08c30a2721 321 SUPERFAMILY SSF54631 182 249 1.61E-7 T 31-10-2018 DFR85_03725 9f988b47c56b9d1fd2a82c08c30a2721 321 SUPERFAMILY SSF54631 60 176 1.14E-20 T 31-10-2018 DFR85_03725 9f988b47c56b9d1fd2a82c08c30a2721 321 Pfam PF00571 CBS domain 128 174 3.9E-9 T 31-10-2018 IPR000644 CBS domain DFR85_03725 9f988b47c56b9d1fd2a82c08c30a2721 321 Pfam PF00571 CBS domain 67 115 5.0E-5 T 31-10-2018 IPR000644 CBS domain DFR85_03725 9f988b47c56b9d1fd2a82c08c30a2721 321 Pfam PF00571 CBS domain 4 54 3.0E-8 T 31-10-2018 IPR000644 CBS domain DFR85_03725 9f988b47c56b9d1fd2a82c08c30a2721 321 Pfam PF00571 CBS domain 184 240 7.6E-6 T 31-10-2018 IPR000644 CBS domain DFR85_03725 9f988b47c56b9d1fd2a82c08c30a2721 321 Gene3D G3DSA:3.10.580.10 1 122 4.4E-22 T 31-10-2018 DFR85_03725 9f988b47c56b9d1fd2a82c08c30a2721 321 Gene3D G3DSA:3.10.580.10 123 247 8.6E-20 T 31-10-2018 DFR85_03725 9f988b47c56b9d1fd2a82c08c30a2721 321 SUPERFAMILY SSF54909 246 319 2.55E-13 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel DFR85_03725 9f988b47c56b9d1fd2a82c08c30a2721 321 Pfam PF01037 Lrp/AsnC ligand binding domain 249 316 7.2E-12 T 31-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DFR85_03725 9f988b47c56b9d1fd2a82c08c30a2721 321 SMART SM00116 190 242 5.3 T 31-10-2018 IPR000644 CBS domain DFR85_03725 9f988b47c56b9d1fd2a82c08c30a2721 321 SMART SM00116 72 115 0.005 T 31-10-2018 IPR000644 CBS domain DFR85_03725 9f988b47c56b9d1fd2a82c08c30a2721 321 SMART SM00116 128 175 1.6E-6 T 31-10-2018 IPR000644 CBS domain DFR85_03725 9f988b47c56b9d1fd2a82c08c30a2721 321 SMART SM00116 9 56 3.0E-5 T 31-10-2018 IPR000644 CBS domain DFR85_03725 9f988b47c56b9d1fd2a82c08c30a2721 321 Gene3D G3DSA:3.30.70.920 248 316 1.1E-16 T 31-10-2018 DFR85_02325 d0bf28f1260ddb8b05dd2380ed36f46e 395 Pfam PF07690 Major Facilitator Superfamily 12 345 1.4E-29 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_02325 d0bf28f1260ddb8b05dd2380ed36f46e 395 SUPERFAMILY SSF103473 8 382 2.22E-55 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_02325 d0bf28f1260ddb8b05dd2380ed36f46e 395 Gene3D G3DSA:1.20.1250.20 4 386 1.0E-52 T 31-10-2018 DFR85_02325 d0bf28f1260ddb8b05dd2380ed36f46e 395 ProSitePatterns PS00217 Sugar transport proteins signature 2. 103 128 - T 31-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DFR85_10075 df19c4deb7fc1b69ff446d3bebb22341 316 Pfam PF04055 Radical SAM superfamily 14 171 1.1E-24 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR85_10075 df19c4deb7fc1b69ff446d3bebb22341 316 SMART SM00729 10 209 2.1E-5 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 DFR85_10075 df19c4deb7fc1b69ff446d3bebb22341 316 TIGRFAM TIGR02668 moaA_archaeal: probable molybdenum cofactor biosynthesis protein A 1 306 2.4E-117 T 31-10-2018 IPR013485 Molybdenum cofactor biosynthesis protein A, archaea GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823 DFR85_10075 df19c4deb7fc1b69ff446d3bebb22341 316 Hamap MF_01225_A GTP 3',8-cyclase [moaA]. 1 306 42.517 T 31-10-2018 IPR013485 Molybdenum cofactor biosynthesis protein A, archaea GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823 DFR85_10075 df19c4deb7fc1b69ff446d3bebb22341 316 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 16 27 - T 31-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 DFR85_10075 df19c4deb7fc1b69ff446d3bebb22341 316 SUPERFAMILY SSF102114 2 298 3.92E-67 T 31-10-2018 DFR85_10075 df19c4deb7fc1b69ff446d3bebb22341 316 Pfam PF06463 Molybdenum Cofactor Synthesis C 179 306 1.1E-24 T 31-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 DFR85_10075 df19c4deb7fc1b69ff446d3bebb22341 316 Pfam PF13353 4Fe-4S single cluster domain 17 115 1.4E-6 T 31-10-2018 DFR85_10075 df19c4deb7fc1b69ff446d3bebb22341 316 Gene3D G3DSA:3.20.20.70 1 307 2.0E-75 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_07830 76e1bc6df35e8908c1048b092ce4d27e 84 SMART SM01136 16 64 4.7E-23 T 31-10-2018 IPR012960 Dyskerin-like Reactome: R-HSA-171319|Reactome: R-HSA-6790901 DFR85_07830 76e1bc6df35e8908c1048b092ce4d27e 84 SUPERFAMILY SSF55120 10 84 4.6E-18 T 31-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 DFR85_07830 76e1bc6df35e8908c1048b092ce4d27e 84 Gene3D G3DSA:2.30.130.70 25 40 2.2E-24 T 31-10-2018 DFR85_07830 76e1bc6df35e8908c1048b092ce4d27e 84 Pfam PF08068 DKCLD (NUC011) domain 20 63 1.9E-15 T 31-10-2018 IPR012960 Dyskerin-like Reactome: R-HSA-171319|Reactome: R-HSA-6790901 DFR85_07830 76e1bc6df35e8908c1048b092ce4d27e 84 Gene3D G3DSA:3.30.2350.10 41 84 2.2E-24 T 31-10-2018 DFR85_09760 49d7a8f2f613fdb444cca77419b3c4b1 260 SUPERFAMILY SSF52833 1 75 3.77E-11 T 31-10-2018 IPR036249 Thioredoxin-like superfamily DFR85_09760 49d7a8f2f613fdb444cca77419b3c4b1 260 Pfam PF13192 Thioredoxin domain 1 74 9.8E-9 T 31-10-2018 IPR012336 Thioredoxin-like fold DFR85_09760 49d7a8f2f613fdb444cca77419b3c4b1 260 Gene3D G3DSA:3.40.30.10 1 75 8.9E-8 T 31-10-2018 DFR85_08195 ed0acd350a575f443e29d8b1b92096d1 150 Gene3D G3DSA:1.10.10.60 94 139 7.1E-15 T 31-10-2018 DFR85_08195 ed0acd350a575f443e29d8b1b92096d1 150 Gene3D G3DSA:1.10.10.60 2 45 4.4E-9 T 31-10-2018 DFR85_08195 ed0acd350a575f443e29d8b1b92096d1 150 Pfam PF13384 Homeodomain-like domain 13 40 5.5E-6 T 31-10-2018 DFR85_08195 ed0acd350a575f443e29d8b1b92096d1 150 Pfam PF13936 Helix-turn-helix domain 95 134 9.6E-7 T 31-10-2018 IPR025246 Transposase IS30-like HTH domain DFR85_08195 ed0acd350a575f443e29d8b1b92096d1 150 Gene3D G3DSA:1.10.10.60 46 89 3.5E-7 T 31-10-2018 DFR85_11370 eefb102e288ef4722df0627b270de7e2 85 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 4 28 - T 31-10-2018 IPR001455 TusA-like domain DFR85_11370 eefb102e288ef4722df0627b270de7e2 85 Pfam PF01206 Sulfurtransferase TusA 3 70 4.0E-13 T 31-10-2018 IPR001455 TusA-like domain DFR85_11370 eefb102e288ef4722df0627b270de7e2 85 Gene3D G3DSA:3.30.110.40 1 70 1.8E-9 T 31-10-2018 IPR036868 TusA-like domain superfamily DFR85_11370 eefb102e288ef4722df0627b270de7e2 85 SUPERFAMILY SSF64307 1 70 4.71E-15 T 31-10-2018 IPR036868 TusA-like domain superfamily DFR85_09375 8577036f7405b8981715f4c381049db9 290 Gene3D G3DSA:3.20.20.70 2 289 1.3E-60 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_09375 8577036f7405b8981715f4c381049db9 290 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 3 287 6.1E-63 T 31-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 DFR85_09375 8577036f7405b8981715f4c381049db9 290 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 225 245 - T 31-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 DFR85_09375 8577036f7405b8981715f4c381049db9 290 PIRSF PIRSF000164 2 289 7.1E-65 T 31-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 DFR85_09375 8577036f7405b8981715f4c381049db9 290 Pfam PF01180 Dihydroorotate dehydrogenase 6 270 6.2E-42 T 31-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 DFR85_09375 8577036f7405b8981715f4c381049db9 290 SUPERFAMILY SSF51395 4 286 5.66E-55 T 31-10-2018 DFR85_10045 2ee33c4e825c6a1fe4d99fc0223e2898 132 SUPERFAMILY SSF52833 24 131 7.72E-34 T 31-10-2018 IPR036249 Thioredoxin-like superfamily DFR85_10045 2ee33c4e825c6a1fe4d99fc0223e2898 132 TIGRFAM TIGR01068 thioredoxin: thioredoxin 34 130 2.0E-31 T 31-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 DFR85_10045 2ee33c4e825c6a1fe4d99fc0223e2898 132 Gene3D G3DSA:3.40.30.10 26 132 3.5E-33 T 31-10-2018 DFR85_10045 2ee33c4e825c6a1fe4d99fc0223e2898 132 PIRSF PIRSF000077 27 132 1.5E-32 T 31-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 DFR85_10045 2ee33c4e825c6a1fe4d99fc0223e2898 132 Pfam PF00085 Thioredoxin 31 130 1.1E-25 T 31-10-2018 IPR013766 Thioredoxin domain GO:0045454 DFR85_08290 393eec41f1091c7b7055ba99c6abe657 352 Pfam PF16575 mRNA cleavage and polyadenylation factor CLP1 P-loop 85 246 4.7E-24 T 31-10-2018 IPR032319 Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain DFR85_08290 393eec41f1091c7b7055ba99c6abe657 352 SUPERFAMILY SSF52540 81 252 1.22E-7 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_08290 393eec41f1091c7b7055ba99c6abe657 352 Gene3D G3DSA:3.40.50.300 72 251 4.0E-17 T 31-10-2018 DFR85_11860 4e616478b68b341d7f3558127656f9db 249 SUPERFAMILY SSF100950 3 243 7.67E-64 T 31-10-2018 IPR037171 NagB/RpiA transferase-like DFR85_11860 4e616478b68b341d7f3558127656f9db 249 Pfam PF01144 Coenzyme A transferase 4 221 1.8E-28 T 31-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 DFR85_11860 4e616478b68b341d7f3558127656f9db 249 Gene3D G3DSA:3.30.30.40 113 152 2.7E-61 T 31-10-2018 DFR85_11860 4e616478b68b341d7f3558127656f9db 249 SMART SM00882 2 222 3.9E-28 T 31-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 DFR85_11860 4e616478b68b341d7f3558127656f9db 249 Gene3D G3DSA:3.40.1080.10 3 241 2.7E-61 T 31-10-2018 DFR85_09350 67e9465a7ee1b5546bec919d98d39749 192 Gene3D G3DSA:3.40.50.2020 2 191 5.7E-51 T 31-10-2018 DFR85_09350 67e9465a7ee1b5546bec919d98d39749 192 Pfam PF00156 Phosphoribosyl transferase domain 57 152 7.3E-19 T 31-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 DFR85_09350 67e9465a7ee1b5546bec919d98d39749 192 SUPERFAMILY SSF53271 9 167 5.9E-42 T 31-10-2018 IPR029057 Phosphoribosyltransferase-like DFR85_09350 67e9465a7ee1b5546bec919d98d39749 192 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 7 165 4.1E-40 T 31-10-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 DFR85_09350 67e9465a7ee1b5546bec919d98d39749 192 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 192 22.593 T 31-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 DFR85_07740 d7149d5e61c32f3f44e4fa1d32571da3 1124 Pfam PF04566 RNA polymerase Rpb2, domain 4 517 580 2.3E-19 T 31-10-2018 IPR007646 RNA polymerase Rpb2, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR85_07740 d7149d5e61c32f3f44e4fa1d32571da3 1124 Gene3D G3DSA:2.40.50.150 679 868 1.0E-146 T 31-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR85_07740 d7149d5e61c32f3f44e4fa1d32571da3 1124 Gene3D G3DSA:3.90.1800.10 1006 1114 6.5E-43 T 31-10-2018 DFR85_07740 d7149d5e61c32f3f44e4fa1d32571da3 1124 Gene3D G3DSA:3.90.1100.10 329 493 5.9E-45 T 31-10-2018 DFR85_07740 d7149d5e61c32f3f44e4fa1d32571da3 1124 Pfam PF04560 RNA polymerase Rpb2, domain 7 1021 1111 4.7E-31 T 31-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR85_07740 d7149d5e61c32f3f44e4fa1d32571da3 1124 Pfam PF04567 RNA polymerase Rpb2, domain 5 601 636 8.5E-9 T 31-10-2018 IPR007647 RNA polymerase Rpb2, domain 5 GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR85_07740 d7149d5e61c32f3f44e4fa1d32571da3 1124 Pfam PF04561 RNA polymerase Rpb2, domain 2 166 341 4.1E-39 T 31-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR85_07740 d7149d5e61c32f3f44e4fa1d32571da3 1124 TIGRFAM TIGR03670 rpoB_arch: DNA-directed RNA polymerase subunit B 517 1116 0.0 T 31-10-2018 IPR019969 DNA-directed RNA polymerase subunit B (Rpo2) GO:0003677|GO:0003899|GO:0006351|GO:0008270 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR85_07740 d7149d5e61c32f3f44e4fa1d32571da3 1124 Gene3D G3DSA:3.90.1100.10 12 165 3.3E-10 T 31-10-2018 DFR85_07740 d7149d5e61c32f3f44e4fa1d32571da3 1124 Pfam PF04565 RNA polymerase Rpb2, domain 3 409 473 4.8E-25 T 31-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR85_07740 d7149d5e61c32f3f44e4fa1d32571da3 1124 SUPERFAMILY SSF64484 4 1114 0.0 T 31-10-2018 DFR85_07740 d7149d5e61c32f3f44e4fa1d32571da3 1124 Pfam PF04563 RNA polymerase beta subunit 19 388 3.0E-56 T 31-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR85_07740 d7149d5e61c32f3f44e4fa1d32571da3 1124 Gene3D G3DSA:2.40.270.10 649 1005 1.0E-146 T 31-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR85_07740 d7149d5e61c32f3f44e4fa1d32571da3 1124 Pfam PF00562 RNA polymerase Rpb2, domain 6 649 1019 1.4E-127 T 31-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR85_07740 d7149d5e61c32f3f44e4fa1d32571da3 1124 Gene3D G3DSA:3.90.1110.10 167 328 4.5E-61 T 31-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR85_07740 d7149d5e61c32f3f44e4fa1d32571da3 1124 ProSitePatterns PS01166 RNA polymerases beta chain signature. 872 884 - T 31-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR85_01935 41cb2a0f9077c5a8606036822136f3f3 328 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 169 3.3E-6 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR85_01935 41cb2a0f9077c5a8606036822136f3f3 328 Gene3D G3DSA:3.50.50.60 135 302 1.5E-11 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_01935 41cb2a0f9077c5a8606036822136f3f3 328 Gene3D G3DSA:3.30.9.10 173 260 1.5E-11 T 31-10-2018 DFR85_01935 41cb2a0f9077c5a8606036822136f3f3 328 SUPERFAMILY SSF51971 2 305 4.47E-14 T 31-10-2018 DFR85_09235 45ecd75adc65e113b6c6131ddc461c05 448 SUPERFAMILY SSF48557 5 377 1.08E-85 T 31-10-2018 IPR008948 L-Aspartase-like GO:0003824 DFR85_09235 45ecd75adc65e113b6c6131ddc461c05 448 Hamap MF_00006 Argininosuccinate lyase [argH]. 1 413 29.986 T 31-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 DFR85_09235 45ecd75adc65e113b6c6131ddc461c05 448 Pfam PF00206 Lyase 66 289 2.4E-43 T 31-10-2018 IPR022761 Fumarate lyase, N-terminal DFR85_09235 45ecd75adc65e113b6c6131ddc461c05 448 Gene3D G3DSA:1.10.275.10 33 218 1.3E-98 T 31-10-2018 IPR024083 Fumarase/histidase, N-terminal DFR85_09235 45ecd75adc65e113b6c6131ddc461c05 448 Gene3D G3DSA:1.10.40.30 345 387 1.3E-98 T 31-10-2018 DFR85_09235 45ecd75adc65e113b6c6131ddc461c05 448 PRINTS PR00145 Argininosuccinate lyase family signature 182 198 3.5E-29 T 31-10-2018 DFR85_09235 45ecd75adc65e113b6c6131ddc461c05 448 PRINTS PR00145 Argininosuccinate lyase family signature 264 280 3.5E-29 T 31-10-2018 DFR85_09235 45ecd75adc65e113b6c6131ddc461c05 448 PRINTS PR00145 Argininosuccinate lyase family signature 90 112 3.5E-29 T 31-10-2018 DFR85_09235 45ecd75adc65e113b6c6131ddc461c05 448 PRINTS PR00145 Argininosuccinate lyase family signature 131 151 3.5E-29 T 31-10-2018 DFR85_09235 45ecd75adc65e113b6c6131ddc461c05 448 PRINTS PR00145 Argininosuccinate lyase family signature 220 244 3.5E-29 T 31-10-2018 DFR85_09235 45ecd75adc65e113b6c6131ddc461c05 448 PRINTS PR00145 Argininosuccinate lyase family signature 299 318 3.5E-29 T 31-10-2018 DFR85_09235 45ecd75adc65e113b6c6131ddc461c05 448 Gene3D G3DSA:1.20.200.10 108 344 1.3E-98 T 31-10-2018 DFR85_09235 45ecd75adc65e113b6c6131ddc461c05 448 TIGRFAM TIGR00838 argH: argininosuccinate lyase 8 377 8.5E-94 T 31-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 DFR85_09235 45ecd75adc65e113b6c6131ddc461c05 448 PRINTS PR00149 Fumarate lyase superfamily signature 220 247 1.7E-16 T 31-10-2018 IPR000362 Fumarate lyase family DFR85_09235 45ecd75adc65e113b6c6131ddc461c05 448 PRINTS PR00149 Fumarate lyase superfamily signature 136 154 1.7E-16 T 31-10-2018 IPR000362 Fumarate lyase family DFR85_09235 45ecd75adc65e113b6c6131ddc461c05 448 PRINTS PR00149 Fumarate lyase superfamily signature 91 109 1.7E-16 T 31-10-2018 IPR000362 Fumarate lyase family DFR85_09235 45ecd75adc65e113b6c6131ddc461c05 448 PRINTS PR00149 Fumarate lyase superfamily signature 264 280 1.7E-16 T 31-10-2018 IPR000362 Fumarate lyase family DFR85_05130 ae9951ebf4bfc71b7b78944225931372 126 Gene3D G3DSA:3.40.50.1010 1 126 1.8E-32 T 31-10-2018 DFR85_05130 ae9951ebf4bfc71b7b78944225931372 126 SUPERFAMILY SSF88723 1 118 8.41E-23 T 31-10-2018 IPR029060 PIN-like domain superfamily DFR85_05130 ae9951ebf4bfc71b7b78944225931372 126 Pfam PF01850 PIN domain 2 117 2.7E-16 T 31-10-2018 IPR002716 PIN domain DFR85_05130 ae9951ebf4bfc71b7b78944225931372 126 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 125 9.564 T 31-10-2018 IPR022907 VapC family GO:0004540 DFR85_08670 707e75a500b678bbd38c8a435d01d256 232 Pfam PF09958 Uncharacterized protein conserved in archaea (DUF2192) 3 226 1.3E-77 T 31-10-2018 IPR018693 Protein of unknown function DUF2192 DFR85_07720 6b3e2ffc9bf3399a1810fd6ad67499ed 146 SMART SM00562 3 140 2.6E-83 T 31-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DFR85_07720 6b3e2ffc9bf3399a1810fd6ad67499ed 146 Gene3D G3DSA:3.30.70.141 1 145 1.0E-62 T 31-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DFR85_07720 6b3e2ffc9bf3399a1810fd6ad67499ed 146 Pfam PF00334 Nucleoside diphosphate kinase 4 138 3.2E-58 T 31-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DFR85_07720 6b3e2ffc9bf3399a1810fd6ad67499ed 146 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 6.0E-42 T 31-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DFR85_07720 6b3e2ffc9bf3399a1810fd6ad67499ed 146 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 6.0E-42 T 31-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DFR85_07720 6b3e2ffc9bf3399a1810fd6ad67499ed 146 PRINTS PR01243 Nucleoside diphosphate kinase signature 6 28 6.0E-42 T 31-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DFR85_07720 6b3e2ffc9bf3399a1810fd6ad67499ed 146 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 6.0E-42 T 31-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DFR85_07720 6b3e2ffc9bf3399a1810fd6ad67499ed 146 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 6.0E-42 T 31-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DFR85_07720 6b3e2ffc9bf3399a1810fd6ad67499ed 146 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 3 138 35.437 T 31-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DFR85_07720 6b3e2ffc9bf3399a1810fd6ad67499ed 146 SUPERFAMILY SSF54919 1 140 1.96E-58 T 31-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DFR85_07720 6b3e2ffc9bf3399a1810fd6ad67499ed 146 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 114 122 - T 31-10-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 DFR85_07920 e350401895edc4bb0266c7241e6c9ce0 147 SUPERFAMILY SSF53098 5 128 5.18E-22 T 31-10-2018 IPR012337 Ribonuclease H-like superfamily DFR85_07920 e350401895edc4bb0266c7241e6c9ce0 147 Gene3D G3DSA:3.30.420.10 1 147 3.4E-39 T 31-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 DFR85_07920 e350401895edc4bb0266c7241e6c9ce0 147 Pfam PF13456 Reverse transcriptase-like 36 130 4.6E-20 T 31-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 DFR85_04480 c99f4671b4689c4a8727c550a4ebd46c 679 Pfam PF04471 Restriction endonuclease 8 123 4.6E-26 T 31-10-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 DFR85_04480 c99f4671b4689c4a8727c550a4ebd46c 679 Gene3D G3DSA:3.40.1350.10 12 128 1.1E-9 T 31-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 DFR85_04480 c99f4671b4689c4a8727c550a4ebd46c 679 SUPERFAMILY SSF52980 12 126 4.4E-19 T 31-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 DFR85_05180 d1fa3e9e2df964111c984b4d63440059 64 SUPERFAMILY SSF47598 20 60 2.3E-8 T 31-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 DFR85_05180 d1fa3e9e2df964111c984b4d63440059 64 Pfam PF01402 Ribbon-helix-helix protein, copG family 22 59 8.3E-9 T 31-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 DFR85_05180 d1fa3e9e2df964111c984b4d63440059 64 Gene3D G3DSA:1.10.1220.10 26 60 3.8E-7 T 31-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 DFR85_07555 c8b01b0d46e8b9605891decd8981ab57 165 Pfam PF04034 Ribosome biogenesis protein, C-terminal 36 161 1.0E-41 T 31-10-2018 IPR007177 Ribosome biogenesis protein, C-terminal Reactome: R-HSA-6790901 DFR85_07555 c8b01b0d46e8b9605891decd8981ab57 165 Pfam PF04068 Possible Fer4-like domain in RNase L inhibitor, RLI 3 31 1.1E-11 T 31-10-2018 IPR007209 RNase L inhibitor RLI, possible metal-binding domain DFR85_07555 c8b01b0d46e8b9605891decd8981ab57 165 Hamap MF_01116 Probable ribosome biogenesis protein . 1 162 32.576 T 31-10-2018 IPR022968 Ribosome biogenesis protein Reactome: R-HSA-6790901 DFR85_07555 c8b01b0d46e8b9605891decd8981ab57 165 ProDom PD016638 UPF0293 SIMILAR RNASE YOR006C RNA COMPONENT SACCHAROMYCES P RIKEN CERVISIAE 26 159 2.0E-30 T 31-10-2018 IPR007177 Ribosome biogenesis protein, C-terminal Reactome: R-HSA-6790901 DFR85_07395 94110be187ece7371e34b509a65f6e91 145 Gene3D G3DSA:3.30.310.60 77 137 3.3E-21 T 31-10-2018 IPR037156 Like-Sm ribonucleoprotein, C-terminal domain superfamily DFR85_07395 94110be187ece7371e34b509a65f6e91 145 Gene3D G3DSA:2.30.30.100 7 73 3.3E-11 T 31-10-2018 DFR85_07395 94110be187ece7371e34b509a65f6e91 145 SUPERFAMILY SSF50182 9 137 3.27E-16 T 31-10-2018 IPR010920 LSM domain superfamily DFR85_07395 94110be187ece7371e34b509a65f6e91 145 Pfam PF14894 Lsm C-terminal 80 141 5.6E-29 T 31-10-2018 IPR028277 Lsm, C-terminal DFR85_03465 a1f77df76757a914b422982200e9abe5 323 Pfam PF04055 Radical SAM superfamily 22 176 1.6E-19 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR85_03465 a1f77df76757a914b422982200e9abe5 323 Gene3D G3DSA:3.20.20.70 13 313 6.1E-41 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_03465 a1f77df76757a914b422982200e9abe5 323 Pfam PF13353 4Fe-4S single cluster domain 23 132 2.6E-7 T 31-10-2018 DFR85_03465 a1f77df76757a914b422982200e9abe5 323 PIRSF PIRSF037420 254 309 0.45 T 31-10-2018 IPR017200 Coenzyme PQQ synthesis protein E DFR85_03465 a1f77df76757a914b422982200e9abe5 323 PIRSF PIRSF037420 3 238 3.4E-37 T 31-10-2018 IPR017200 Coenzyme PQQ synthesis protein E DFR85_03465 a1f77df76757a914b422982200e9abe5 323 SUPERFAMILY SSF102114 15 284 1.7E-47 T 31-10-2018 DFR85_03465 a1f77df76757a914b422982200e9abe5 323 SMART SM00729 16 217 0.0016 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 DFR85_15215 ad2b6a3151cb8c69666b3ada7669cefb 335 Pfam PF05762 VWA domain containing CoxE-like protein 123 327 4.0E-27 T 31-10-2018 IPR008912 Uncharacterised protein family CoxE-like DFR85_15215 ad2b6a3151cb8c69666b3ada7669cefb 335 SUPERFAMILY SSF53300 170 296 4.13E-10 T 31-10-2018 IPR036465 von Willebrand factor A-like domain superfamily DFR85_15215 ad2b6a3151cb8c69666b3ada7669cefb 335 Gene3D G3DSA:3.40.50.410 160 295 9.3E-6 T 31-10-2018 IPR036465 von Willebrand factor A-like domain superfamily DFR85_14930 33b8fedd8f1890067c72f4f4767d5496 194 Gene3D G3DSA:1.10.1660.10 1 55 1.1E-9 T 31-10-2018 DFR85_14930 33b8fedd8f1890067c72f4f4767d5496 194 Pfam PF12728 Helix-turn-helix domain 1 48 5.3E-11 T 31-10-2018 DFR85_14930 33b8fedd8f1890067c72f4f4767d5496 194 ProSitePatterns PS00397 Site-specific recombinases active site. 59 67 - T 31-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 DFR85_14930 33b8fedd8f1890067c72f4f4767d5496 194 SUPERFAMILY SSF53041 54 180 4.58E-21 T 31-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 DFR85_14930 33b8fedd8f1890067c72f4f4767d5496 194 Pfam PF00239 Resolvase, N terminal domain 56 187 2.3E-18 T 31-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 DFR85_14930 33b8fedd8f1890067c72f4f4767d5496 194 SMART SM00857 56 192 9.4E-19 T 31-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 DFR85_14930 33b8fedd8f1890067c72f4f4767d5496 194 Gene3D G3DSA:3.40.50.1390 56 150 4.0E-27 T 31-10-2018 DFR85_14930 33b8fedd8f1890067c72f4f4767d5496 194 SUPERFAMILY SSF46955 1 54 6.41E-11 T 31-10-2018 IPR009061 Putative DNA-binding domain superfamily DFR85_11180 bc3d6c9c148a9ab2157c8763297d58e2 244 SUPERFAMILY SSF55979 2 116 1.16E-24 T 31-10-2018 DFR85_11180 bc3d6c9c148a9ab2157c8763297d58e2 244 SUPERFAMILY SSF55979 124 244 1.44E-24 T 31-10-2018 DFR85_11180 bc3d6c9c148a9ab2157c8763297d58e2 244 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 33 51 3.1E-9 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 DFR85_11180 bc3d6c9c148a9ab2157c8763297d58e2 244 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 191 205 3.1E-9 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 DFR85_11180 bc3d6c9c148a9ab2157c8763297d58e2 244 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 9 28 3.1E-9 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 DFR85_11180 bc3d6c9c148a9ab2157c8763297d58e2 244 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 229 244 3.1E-9 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 DFR85_11180 bc3d6c9c148a9ab2157c8763297d58e2 244 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 55 79 3.1E-9 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 DFR85_11180 bc3d6c9c148a9ab2157c8763297d58e2 244 Hamap MF_00317 DNA polymerase sliding clamp [pcn]. 1 243 25.255 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 DFR85_11180 bc3d6c9c148a9ab2157c8763297d58e2 244 Pfam PF02747 Proliferating cell nuclear antigen, C-terminal domain 131 241 8.7E-10 T 31-10-2018 IPR022649 Proliferating cell nuclear antigen, PCNA, C-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 DFR85_11180 bc3d6c9c148a9ab2157c8763297d58e2 244 Pfam PF00705 Proliferating cell nuclear antigen, N-terminal domain 4 95 4.8E-10 T 31-10-2018 IPR022648 Proliferating cell nuclear antigen, PCNA, N-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 DFR85_11180 bc3d6c9c148a9ab2157c8763297d58e2 244 ProSitePatterns PS01251 Proliferating cell nuclear antigen signature 1. 33 56 - T 31-10-2018 IPR022659 Proliferating cell nuclear antigen, PCNA, conserved site Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 DFR85_11180 bc3d6c9c148a9ab2157c8763297d58e2 244 Gene3D G3DSA:3.70.10.10 2 243 8.2E-55 T 31-10-2018 DFR85_07075 5e2ce7bba95fbf7027302ffaa5dadd00 229 Pfam PF07650 KH domain 18 90 4.5E-15 T 31-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07075 5e2ce7bba95fbf7027302ffaa5dadd00 229 SUPERFAMILY SSF54814 8 96 5.23E-23 T 31-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 DFR85_07075 5e2ce7bba95fbf7027302ffaa5dadd00 229 SMART SM00322 39 105 1.1E-4 T 31-10-2018 IPR004087 K Homology domain GO:0003676 DFR85_07075 5e2ce7bba95fbf7027302ffaa5dadd00 229 Hamap MF_01309_A 30S ribosomal protein S3 [rpsC]. 3 197 39.303 T 31-10-2018 IPR027488 Ribosomal protein S3, archaeal GO:0003735|GO:0006412|GO:0015935 DFR85_07075 5e2ce7bba95fbf7027302ffaa5dadd00 229 TIGRFAM TIGR01008 uS3_euk_arch: ribosomal protein uS3 4 194 2.4E-70 T 31-10-2018 IPR005703 Ribosomal protein S3, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07075 5e2ce7bba95fbf7027302ffaa5dadd00 229 Gene3D G3DSA:3.30.300.20 1 87 2.5E-23 T 31-10-2018 IPR015946 K homology domain-like, alpha/beta DFR85_07075 5e2ce7bba95fbf7027302ffaa5dadd00 229 Gene3D G3DSA:3.30.1140.32 88 221 6.1E-32 T 31-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07075 5e2ce7bba95fbf7027302ffaa5dadd00 229 ProSitePatterns PS00548 Ribosomal protein S3 signature. 142 178 - T 31-10-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07075 5e2ce7bba95fbf7027302ffaa5dadd00 229 SUPERFAMILY SSF54821 87 186 2.22E-25 T 31-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07075 5e2ce7bba95fbf7027302ffaa5dadd00 229 Pfam PF00189 Ribosomal protein S3, C-terminal domain 101 183 4.8E-22 T 31-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_09310 aa9e7caebe0e6d779d86ac453fab6143 214 Pfam PF02676 Methyltransferase TYW3 8 188 1.3E-29 T 31-10-2018 IPR003827 tRNA wybutosine-synthesizing protein MetaCyc: PWY-7286|Reactome: R-HSA-6782861 DFR85_09310 aa9e7caebe0e6d779d86ac453fab6143 214 Gene3D G3DSA:3.30.1960.10 1 189 1.7E-56 T 31-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 DFR85_09310 aa9e7caebe0e6d779d86ac453fab6143 214 SUPERFAMILY SSF111278 3 189 2.48E-49 T 31-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 DFR85_09310 aa9e7caebe0e6d779d86ac453fab6143 214 Hamap MF_00266 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase [taw3]. 5 191 29.373 T 31-10-2018 IPR022908 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase GO:0008175|GO:0030488|GO:0031591 MetaCyc: PWY-7286 DFR85_14570 662768ea6f2e6255ede7841ad02d14b7 396 Gene3D G3DSA:3.40.50.300 6 227 2.3E-37 T 31-10-2018 DFR85_14570 662768ea6f2e6255ede7841ad02d14b7 396 Pfam PF01637 ATPase domain predominantly from Archaea 20 269 5.9E-20 T 31-10-2018 IPR011579 ATPase domain GO:0005524 DFR85_14570 662768ea6f2e6255ede7841ad02d14b7 396 Gene3D G3DSA:1.10.8.60 229 307 9.6E-21 T 31-10-2018 DFR85_14570 662768ea6f2e6255ede7841ad02d14b7 396 SUPERFAMILY SSF52540 9 293 7.78E-40 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_14570 662768ea6f2e6255ede7841ad02d14b7 396 Gene3D G3DSA:1.10.10.10 310 381 1.7E-5 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_15745 1709043542a8b0a6f672fc981c3b96f6 335 SUPERFAMILY SSF54862 6 82 2.51E-15 T 31-10-2018 DFR85_15745 1709043542a8b0a6f672fc981c3b96f6 335 SUPERFAMILY SSF54631 221 323 3.66E-10 T 31-10-2018 DFR85_15745 1709043542a8b0a6f672fc981c3b96f6 335 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 53 64 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR85_15745 1709043542a8b0a6f672fc981c3b96f6 335 Gene3D G3DSA:3.10.580.10 82 220 6.0E-22 T 31-10-2018 DFR85_15745 1709043542a8b0a6f672fc981c3b96f6 335 SMART SM00116 94 142 0.035 T 31-10-2018 IPR000644 CBS domain DFR85_15745 1709043542a8b0a6f672fc981c3b96f6 335 SMART SM00116 147 194 1.6E-4 T 31-10-2018 IPR000644 CBS domain DFR85_15745 1709043542a8b0a6f672fc981c3b96f6 335 SMART SM00116 221 267 3.8 T 31-10-2018 IPR000644 CBS domain DFR85_15745 1709043542a8b0a6f672fc981c3b96f6 335 Gene3D G3DSA:3.10.580.10 221 327 2.1E-8 T 31-10-2018 DFR85_15745 1709043542a8b0a6f672fc981c3b96f6 335 Pfam PF00571 CBS domain 224 266 0.0022 T 31-10-2018 IPR000644 CBS domain DFR85_15745 1709043542a8b0a6f672fc981c3b96f6 335 Pfam PF00571 CBS domain 147 192 2.1E-7 T 31-10-2018 IPR000644 CBS domain DFR85_15745 1709043542a8b0a6f672fc981c3b96f6 335 Pfam PF00571 CBS domain 87 133 2.6E-5 T 31-10-2018 IPR000644 CBS domain DFR85_15745 1709043542a8b0a6f672fc981c3b96f6 335 Gene3D G3DSA:3.30.70.20 12 81 1.6E-8 T 31-10-2018 DFR85_15745 1709043542a8b0a6f672fc981c3b96f6 335 Pfam PF00037 4Fe-4S binding domain 47 69 1.6E-6 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR85_15745 1709043542a8b0a6f672fc981c3b96f6 335 SUPERFAMILY SSF54631 86 193 7.19E-20 T 31-10-2018 DFR85_00870 5e1e22ab75e3f8e605915a8fb7fa3ef2 241 SUPERFAMILY SSF53790 2 238 9.03E-68 T 31-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 DFR85_00870 5e1e22ab75e3f8e605915a8fb7fa3ef2 241 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 8 22 - T 31-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 DFR85_00870 5e1e22ab75e3f8e605915a8fb7fa3ef2 241 Gene3D G3DSA:3.30.950.10 118 241 1.0E-33 T 31-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 DFR85_00870 5e1e22ab75e3f8e605915a8fb7fa3ef2 241 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 210 1.1E-47 T 31-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 DFR85_00870 5e1e22ab75e3f8e605915a8fb7fa3ef2 241 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 82 115 - T 31-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 DFR85_00870 5e1e22ab75e3f8e605915a8fb7fa3ef2 241 Gene3D G3DSA:3.40.1010.10 1 117 8.8E-42 T 31-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 DFR85_00870 5e1e22ab75e3f8e605915a8fb7fa3ef2 241 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 3 234 8.9E-88 T 31-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 DFR85_06535 d57f3cc2342890ca7e1984a3aab0099d 95 SUPERFAMILY SSF69695 9 88 4.32E-12 T 31-10-2018 IPR036521 Signal recognition particle, subunit SRP19-like superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 DFR85_06535 d57f3cc2342890ca7e1984a3aab0099d 95 Gene3D G3DSA:3.30.56.30 1 94 2.9E-24 T 31-10-2018 IPR036521 Signal recognition particle, subunit SRP19-like superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 DFR85_11290 4ba13e46590128d698b3a1ff24470fbb 317 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 168 254 9.2E-8 T 31-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 DFR85_11290 4ba13e46590128d698b3a1ff24470fbb 317 Gene3D G3DSA:3.40.50.2000 165 258 1.6E-7 T 31-10-2018 DFR85_11290 4ba13e46590128d698b3a1ff24470fbb 317 SUPERFAMILY SSF53756 4 250 8.27E-12 T 31-10-2018 DFR85_11290 4ba13e46590128d698b3a1ff24470fbb 317 Gene3D G3DSA:3.40.50.2000 2 164 1.9E-9 T 31-10-2018 DFR85_07865 522a2df32064954ab8d00f0447fdc8e4 245 ProDom PD313320 GTP III HYDROLASE CYCLOHYDROLASE RIBOFLAVIN BIOSYNTHESIS 3.5.4.- FAMILY MAGNESIUM GGDN 10 239 8.0E-50 T 31-10-2018 IPR007839 GTP cyclohydrolase III GO:0003933|GO:0009058 KEGG: 00740+3.5.4.29|MetaCyc: PWY-6167 DFR85_07865 522a2df32064954ab8d00f0447fdc8e4 245 Gene3D G3DSA:3.30.70.1230 9 126 6.8E-25 T 31-10-2018 IPR029787 Nucleotide cyclase DFR85_07865 522a2df32064954ab8d00f0447fdc8e4 245 Hamap MF_00608 GTP cyclohydrolase III [gch3]. 12 241 30.189 T 31-10-2018 IPR007839 GTP cyclohydrolase III GO:0003933|GO:0009058 KEGG: 00740+3.5.4.29|MetaCyc: PWY-6167 DFR85_07865 522a2df32064954ab8d00f0447fdc8e4 245 Pfam PF05165 GTP cyclohydrolase III 14 234 1.8E-34 T 31-10-2018 IPR007839 GTP cyclohydrolase III GO:0003933|GO:0009058 KEGG: 00740+3.5.4.29|MetaCyc: PWY-6167 DFR85_07865 522a2df32064954ab8d00f0447fdc8e4 245 Gene3D G3DSA:3.30.70.270 128 241 1.1E-28 T 31-10-2018 DFR85_07865 522a2df32064954ab8d00f0447fdc8e4 245 PIRSF PIRSF009265 9 243 7.7E-60 T 31-10-2018 IPR007839 GTP cyclohydrolase III GO:0003933|GO:0009058 KEGG: 00740+3.5.4.29|MetaCyc: PWY-6167 DFR85_03165 62681a937b09214d770506180553611b 318 SUPERFAMILY SSF50331 238 308 2.96E-8 T 31-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal DFR85_03165 62681a937b09214d770506180553611b 318 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DFR85_03165 62681a937b09214d770506180553611b 318 SMART SM00382 27 207 2.0E-15 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_03165 62681a937b09214d770506180553611b 318 Gene3D G3DSA:3.40.50.300 3 217 4.7E-66 T 31-10-2018 DFR85_03165 62681a937b09214d770506180553611b 318 Pfam PF00005 ABC transporter 18 157 2.1E-34 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR85_03165 62681a937b09214d770506180553611b 318 SUPERFAMILY SSF52540 3 237 2.46E-82 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_03165 62681a937b09214d770506180553611b 318 Gene3D G3DSA:2.40.50.940 218 263 1.0E-8 T 31-10-2018 DFR85_09960 a417a24a950d4c0d2aa0af4a8dc8c513 353 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 228 265 4.1E-6 T 31-10-2018 IPR001451 Hexapeptide repeat DFR85_09960 a417a24a950d4c0d2aa0af4a8dc8c513 353 Pfam PF00483 Nucleotidyl transferase 2 151 1.8E-14 T 31-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 DFR85_09960 a417a24a950d4c0d2aa0af4a8dc8c513 353 Gene3D G3DSA:3.90.550.10 1 210 5.5E-33 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_09960 a417a24a950d4c0d2aa0af4a8dc8c513 353 Gene3D G3DSA:2.160.10.10 211 350 4.6E-23 T 31-10-2018 DFR85_09960 a417a24a950d4c0d2aa0af4a8dc8c513 353 SUPERFAMILY SSF53448 1 286 1.66E-36 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_09960 a417a24a950d4c0d2aa0af4a8dc8c513 353 SUPERFAMILY SSF51161 215 325 1.0E-18 T 31-10-2018 IPR011004 Trimeric LpxA-like superfamily DFR85_02815 53d9ce24235b248e85bd50aa53039e19 438 Pfam PF00120 Glutamine synthetase, catalytic domain 110 435 5.0E-92 T 31-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DFR85_02815 53d9ce24235b248e85bd50aa53039e19 438 Gene3D G3DSA:3.30.590.10 110 437 9.8E-100 T 31-10-2018 DFR85_02815 53d9ce24235b248e85bd50aa53039e19 438 SUPERFAMILY SSF54368 4 105 1.15E-9 T 31-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DFR85_02815 53d9ce24235b248e85bd50aa53039e19 438 SUPERFAMILY SSF55931 106 435 5.59E-92 T 31-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 DFR85_02815 53d9ce24235b248e85bd50aa53039e19 438 Gene3D G3DSA:3.10.20.70 1 108 5.4E-9 T 31-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DFR85_02815 53d9ce24235b248e85bd50aa53039e19 438 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 230 245 - T 31-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 DFR85_02815 53d9ce24235b248e85bd50aa53039e19 438 SMART SM01230 106 356 3.5E-76 T 31-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DFR85_09145 de0c0bc36735ae2ae415deb517e8f18b 131 Pfam PF10929 Protein of unknown function (DUF2811) 8 50 2.0E-4 T 31-10-2018 IPR021231 Protein of unknown function DUF2811 DFR85_09145 de0c0bc36735ae2ae415deb517e8f18b 131 SUPERFAMILY SSF55021 52 126 3.66E-15 T 31-10-2018 DFR85_09145 de0c0bc36735ae2ae415deb517e8f18b 131 SUPERFAMILY SSF47598 2 46 3.71E-7 T 31-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 DFR85_09145 de0c0bc36735ae2ae415deb517e8f18b 131 Hamap MF_00476 Nickel-responsive regulator [nikR]. 3 129 19.564 T 31-10-2018 IPR022988 Nickel-responsive transcriptional regulator NikR GO:0003677|GO:0006355|GO:0010045|GO:0016151 DFR85_09145 de0c0bc36735ae2ae415deb517e8f18b 131 Gene3D G3DSA:3.30.70.1150 29 127 5.1E-23 T 31-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal DFR85_09145 de0c0bc36735ae2ae415deb517e8f18b 131 Pfam PF08753 NikR C terminal nickel binding domain 53 125 1.7E-19 T 31-10-2018 IPR014864 Transcription factor, NikR, nickel binding C-terminal DFR85_00610 c481abca9bcd941a3b37a9a3aeb41234 396 PIRSF PIRSF000429 1 393 1.6E-118 T 31-10-2018 IPR002155 Thiolase GO:0016747 DFR85_00610 c481abca9bcd941a3b37a9a3aeb41234 396 SUPERFAMILY SSF53901 270 391 2.06E-35 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR85_00610 c481abca9bcd941a3b37a9a3aeb41234 396 SUPERFAMILY SSF53901 3 269 5.26E-77 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR85_00610 c481abca9bcd941a3b37a9a3aeb41234 396 Pfam PF00108 Thiolase, N-terminal domain 4 262 3.2E-86 T 31-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 DFR85_00610 c481abca9bcd941a3b37a9a3aeb41234 396 Pfam PF02803 Thiolase, C-terminal domain 270 390 1.0E-36 T 31-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 DFR85_00610 c481abca9bcd941a3b37a9a3aeb41234 396 ProSitePatterns PS00737 Thiolases signature 2. 338 354 - T 31-10-2018 IPR020613 Thiolase, conserved site GO:0016747 DFR85_00610 c481abca9bcd941a3b37a9a3aeb41234 396 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 390 3.2E-136 T 31-10-2018 IPR002155 Thiolase GO:0016747 DFR85_00610 c481abca9bcd941a3b37a9a3aeb41234 396 Gene3D G3DSA:3.40.47.10 5 275 1.9E-137 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR85_00610 c481abca9bcd941a3b37a9a3aeb41234 396 Gene3D G3DSA:3.40.47.10 126 389 1.9E-137 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR85_08565 efdea2c5a933c875004bb46a391b2d77 211 Gene3D G3DSA:3.40.1010.10 1 99 1.2E-22 T 31-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 DFR85_08565 efdea2c5a933c875004bb46a391b2d77 211 SUPERFAMILY SSF53790 1 209 3.79E-39 T 31-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 DFR85_08565 efdea2c5a933c875004bb46a391b2d77 211 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 1 195 4.4E-29 T 31-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 DFR85_08565 efdea2c5a933c875004bb46a391b2d77 211 Gene3D G3DSA:3.30.950.10 100 210 1.7E-12 T 31-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 DFR85_00650 dd6fbd9385fdff9801f7d22d15290ce7 573 Pfam PF00437 Type II/IV secretion system protein 224 429 2.1E-43 T 31-10-2018 IPR001482 Type II/IV secretion system protein DFR85_00650 dd6fbd9385fdff9801f7d22d15290ce7 573 Gene3D G3DSA:3.40.50.300 281 565 9.1E-76 T 31-10-2018 DFR85_00650 dd6fbd9385fdff9801f7d22d15290ce7 573 SUPERFAMILY SSF52540 158 470 2.83E-43 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_00650 dd6fbd9385fdff9801f7d22d15290ce7 573 Gene3D G3DSA:3.30.450.380 55 279 7.2E-51 T 31-10-2018 DFR85_01605 53b27381928267627679ce0cbe581630 269 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 151 236 5.2E-8 T 31-10-2018 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like DFR85_01605 53b27381928267627679ce0cbe581630 269 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 3 121 1.5E-18 T 31-10-2018 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like DFR85_01605 53b27381928267627679ce0cbe581630 269 Gene3D G3DSA:3.10.490.10 127 265 1.6E-22 T 31-10-2018 DFR85_01605 53b27381928267627679ce0cbe581630 269 SUPERFAMILY SSF110857 130 256 1.44E-17 T 31-10-2018 IPR036568 Gamma-glutamyl cyclotransferase-like superfamily DFR85_01605 53b27381928267627679ce0cbe581630 269 SUPERFAMILY SSF110857 1 123 1.7E-27 T 31-10-2018 IPR036568 Gamma-glutamyl cyclotransferase-like superfamily DFR85_01605 53b27381928267627679ce0cbe581630 269 Gene3D G3DSA:3.10.490.10 1 126 3.3E-27 T 31-10-2018 DFR85_05590 edfba10e7f2e0465caf44cf2739a9f92 213 TIGRFAM TIGR04306 salvage_TenA: thiaminase II 11 205 3.0E-43 T 31-10-2018 IPR027574 Thiaminase II GO:0006772|GO:0050334 KEGG: 00730+3.5.99.2|MetaCyc: PWY-6899|MetaCyc: PWY-7356 DFR85_05590 edfba10e7f2e0465caf44cf2739a9f92 213 Gene3D G3DSA:1.20.910.10 1 207 5.6E-60 T 31-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 DFR85_05590 edfba10e7f2e0465caf44cf2739a9f92 213 Pfam PF03070 TENA/THI-4/PQQC family 7 205 5.8E-39 T 31-10-2018 IPR004305 Thiaminase-2/PQQC DFR85_05590 edfba10e7f2e0465caf44cf2739a9f92 213 SUPERFAMILY SSF48613 1 204 1.04E-62 T 31-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 DFR85_09865 f88774cc1e002e4d1656092f5c487fca 189 Hamap MF_00975 Exosome complex component Csl4 [csl4]. 7 185 24.412 T 31-10-2018 IPR030850 Exosome complex component Csl4, archaea GO:0000178|GO:0006396 DFR85_09865 f88774cc1e002e4d1656092f5c487fca 189 SUPERFAMILY SSF110324 6 57 2.25E-11 T 31-10-2018 DFR85_09865 f88774cc1e002e4d1656092f5c487fca 189 Gene3D G3DSA:2.20.70.10 147 180 3.6E-11 T 31-10-2018 DFR85_09865 f88774cc1e002e4d1656092f5c487fca 189 SMART SM00316 64 140 2.1E-4 T 31-10-2018 IPR022967 RNA-binding domain, S1 DFR85_09865 f88774cc1e002e4d1656092f5c487fca 189 Gene3D G3DSA:2.40.50.100 6 56 5.9E-12 T 31-10-2018 DFR85_09865 f88774cc1e002e4d1656092f5c487fca 189 SUPERFAMILY SSF50249 68 178 9.43E-21 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR85_09865 f88774cc1e002e4d1656092f5c487fca 189 Pfam PF14382 Exosome complex exonuclease RRP4 N-terminal region 7 42 6.7E-8 T 31-10-2018 IPR025721 Exosome complex component, N-terminal domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 DFR85_09865 f88774cc1e002e4d1656092f5c487fca 189 Gene3D G3DSA:2.40.50.140 62 146 1.6E-18 T 31-10-2018 DFR85_15700 759cfe87c2fa48ce6ed49dee0b7dccb9 331 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 132 1.2E-24 T 31-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DFR85_15700 759cfe87c2fa48ce6ed49dee0b7dccb9 331 Gene3D G3DSA:3.90.180.10 1 330 3.7E-85 T 31-10-2018 DFR85_15700 759cfe87c2fa48ce6ed49dee0b7dccb9 331 Pfam PF00107 Zinc-binding dehydrogenase 176 287 1.1E-22 T 31-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DFR85_15700 759cfe87c2fa48ce6ed49dee0b7dccb9 331 SUPERFAMILY SSF50129 1 170 3.35E-44 T 31-10-2018 IPR011032 GroES-like superfamily DFR85_15700 759cfe87c2fa48ce6ed49dee0b7dccb9 331 SMART SM00829 9 328 8.3E-11 T 31-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DFR85_15700 759cfe87c2fa48ce6ed49dee0b7dccb9 331 SUPERFAMILY SSF51735 141 303 6.1E-39 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_11040 6fc53e82c247ffff0d4621b98cbd2be9 175 Pfam PF01565 FAD binding domain 19 63 3.0E-6 T 31-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 DFR85_11040 6fc53e82c247ffff0d4621b98cbd2be9 175 Gene3D G3DSA:3.30.465.40 15 116 3.7E-12 T 31-10-2018 DFR85_11040 6fc53e82c247ffff0d4621b98cbd2be9 175 SUPERFAMILY SSF56176 18 94 6.54E-12 T 31-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 DFR85_04130 42428b53ceaeaedf0b0e27369c581067 657 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 96 502 5.2E-38 T 31-10-2018 IPR000914 Solute-binding protein family 5 domain DFR85_04130 42428b53ceaeaedf0b0e27369c581067 657 SUPERFAMILY SSF53850 45 590 5.76E-54 T 31-10-2018 DFR85_04130 42428b53ceaeaedf0b0e27369c581067 657 Gene3D G3DSA:3.40.190.10 35 315 2.3E-22 T 31-10-2018 DFR85_04130 42428b53ceaeaedf0b0e27369c581067 657 Gene3D G3DSA:3.10.105.10 331 567 6.6E-29 T 31-10-2018 DFR85_10655 708ea083212a5c3c9bf96dbd3a583f84 207 SUPERFAMILY SSF55261 94 201 8.5E-16 T 31-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 DFR85_10655 708ea083212a5c3c9bf96dbd3a583f84 207 SUPERFAMILY SSF46785 26 89 5.38E-11 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_10655 708ea083212a5c3c9bf96dbd3a583f84 207 Gene3D G3DSA:1.10.10.10 28 92 2.9E-22 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_10655 708ea083212a5c3c9bf96dbd3a583f84 207 Gene3D G3DSA:3.30.1360.30 93 195 2.9E-22 T 31-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 DFR85_14395 b430c40c0e4e6a25d765f071496f0b55 225 Pfam PF04967 HTH DNA binding domain 155 204 1.5E-14 T 31-10-2018 IPR007050 Bacterioopsin activator-type, HTH domain DFR85_06270 75725ac63dcce9e3159294134b7d5018 395 SUPERFAMILY SSF103473 9 384 2.88E-57 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_06270 75725ac63dcce9e3159294134b7d5018 395 Pfam PF07690 Major Facilitator Superfamily 20 344 2.4E-33 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_06270 75725ac63dcce9e3159294134b7d5018 395 Gene3D G3DSA:1.20.1250.20 3 194 1.3E-31 T 31-10-2018 DFR85_06270 75725ac63dcce9e3159294134b7d5018 395 ProSitePatterns PS00217 Sugar transport proteins signature 2. 103 128 - T 31-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DFR85_06270 75725ac63dcce9e3159294134b7d5018 395 Gene3D G3DSA:1.20.1250.20 200 389 1.4E-18 T 31-10-2018 DFR85_07065 bd0cf6b4f29ccd3a33a8d9cb6165d6b0 93 SMART SM00538 7 92 4.1E-4 T 31-10-2018 IPR002730 Ribonuclease P/MRP, subunit p29 GO:0003723|GO:0004540|GO:0006396|GO:0030677 Reactome: R-HSA-6784531 DFR85_07065 bd0cf6b4f29ccd3a33a8d9cb6165d6b0 93 Gene3D G3DSA:2.30.30.210 5 93 4.1E-19 T 31-10-2018 IPR036980 Ribonuclease P/MRP, subunit p29 superfamily GO:0003723|GO:0004540|GO:0008033|GO:0030677 Reactome: R-HSA-6784531 DFR85_07065 bd0cf6b4f29ccd3a33a8d9cb6165d6b0 93 Hamap MF_00754 Ribonuclease P protein component 1 [rnp1]. 12 88 14.354 T 31-10-2018 IPR023538 Ribonuclease P protein component 1 GO:0001682|GO:0004526 DFR85_07065 bd0cf6b4f29ccd3a33a8d9cb6165d6b0 93 SUPERFAMILY SSF101744 13 91 3.49E-21 T 31-10-2018 IPR023534 Rof/RNase P-like Reactome: R-HSA-6784531 DFR85_07065 bd0cf6b4f29ccd3a33a8d9cb6165d6b0 93 Pfam PF01868 Domain of unknown function UPF0086 13 89 1.3E-15 T 31-10-2018 IPR002730 Ribonuclease P/MRP, subunit p29 GO:0003723|GO:0004540|GO:0006396|GO:0030677 Reactome: R-HSA-6784531 DFR85_14990 e6f83213f2c569b4df99499345d8dfb6 370 Gene3D G3DSA:3.30.390.10 3 362 4.6E-100 T 31-10-2018 IPR029017 Enolase-like, N-terminal DFR85_14990 e6f83213f2c569b4df99499345d8dfb6 370 Pfam PF13378 Enolase C-terminal domain-like 151 361 5.1E-56 T 31-10-2018 IPR029065 Enolase C-terminal domain-like DFR85_14990 e6f83213f2c569b4df99499345d8dfb6 370 SUPERFAMILY SSF51604 115 369 5.9E-67 T 31-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily DFR85_14990 e6f83213f2c569b4df99499345d8dfb6 370 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 30 127 6.6E-14 T 31-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain DFR85_14990 e6f83213f2c569b4df99499345d8dfb6 370 Gene3D G3DSA:3.20.20.120 120 359 4.6E-100 T 31-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily DFR85_14990 e6f83213f2c569b4df99499345d8dfb6 370 SMART SM00922 148 244 3.4E-19 T 31-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal DFR85_14990 e6f83213f2c569b4df99499345d8dfb6 370 SUPERFAMILY SSF54826 1 129 3.21E-24 T 31-10-2018 DFR85_03115 e3e6556c02bdabe536c9ae71501f7144 270 Pfam PF06053 Domain of unknown function (DUF929) 11 235 2.2E-37 T 31-10-2018 IPR009272 Protein of unknown function DUF929 DFR85_13155 d2dd1ef23bc84aad1823746d02c5023c 244 Gene3D G3DSA:3.30.70.1890 1 118 1.9E-14 T 31-10-2018 DFR85_13155 d2dd1ef23bc84aad1823746d02c5023c 244 Gene3D G3DSA:3.30.70.1900 123 234 2.6E-24 T 31-10-2018 DFR85_13155 d2dd1ef23bc84aad1823746d02c5023c 244 Pfam PF01881 CRISPR associated protein Cas6 94 232 1.3E-29 T 31-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 DFR85_13155 d2dd1ef23bc84aad1823746d02c5023c 244 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 47 232 8.0E-34 T 31-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 DFR85_13155 d2dd1ef23bc84aad1823746d02c5023c 244 PIRSF PIRSF005054 1 237 4.0E-52 T 31-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 DFR85_07580 26ddb58170db42c9610806c8a0c7e688 172 Hamap MF_00582 UPF0215 protein . 1 167 20.894 T 31-10-2018 IPR002802 Protein of unknown function DUF99 DFR85_07580 26ddb58170db42c9610806c8a0c7e688 172 ProDom PD016744 UPF0215 ST0304 TK2033 MA4269 PAE0952 SSO0256 NEQ431 MK0057 PTO0905 TV0037 54 162 3.0E-24 T 31-10-2018 IPR002802 Protein of unknown function DUF99 DFR85_07580 26ddb58170db42c9610806c8a0c7e688 172 PIRSF PIRSF006380 1 172 4.7E-37 T 31-10-2018 IPR002802 Protein of unknown function DUF99 DFR85_07580 26ddb58170db42c9610806c8a0c7e688 172 Gene3D G3DSA:3.30.2170.10 2 171 1.7E-14 T 31-10-2018 DFR85_07580 26ddb58170db42c9610806c8a0c7e688 172 Pfam PF01949 Protein of unknown function DUF99 3 165 1.5E-15 T 31-10-2018 IPR002802 Protein of unknown function DUF99 DFR85_08845 ee88680c7aea0f443ba6ef608edd7510 780 Gene3D G3DSA:1.10.132.60 621 779 1.7E-42 T 31-10-2018 DFR85_08845 ee88680c7aea0f443ba6ef608edd7510 780 SUPERFAMILY SSF53098 4 397 8.18E-73 T 31-10-2018 IPR012337 Ribonuclease H-like superfamily DFR85_08845 ee88680c7aea0f443ba6ef608edd7510 780 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 558 566 5.4E-11 T 31-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DFR85_08845 ee88680c7aea0f443ba6ef608edd7510 780 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 423 436 5.4E-11 T 31-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DFR85_08845 ee88680c7aea0f443ba6ef608edd7510 780 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 506 518 5.4E-11 T 31-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DFR85_08845 ee88680c7aea0f443ba6ef608edd7510 780 TIGRFAM TIGR00592 pol2: DNA polymerase (pol2) 407 758 2.6E-74 T 31-10-2018 DFR85_08845 ee88680c7aea0f443ba6ef608edd7510 780 SUPERFAMILY SSF56672 377 768 7.23E-118 T 31-10-2018 DFR85_08845 ee88680c7aea0f443ba6ef608edd7510 780 Gene3D G3DSA:3.30.342.10 8 393 3.8E-75 T 31-10-2018 DFR85_08845 ee88680c7aea0f443ba6ef608edd7510 780 Gene3D G3DSA:1.10.287.690 471 522 3.4E-19 T 31-10-2018 DFR85_08845 ee88680c7aea0f443ba6ef608edd7510 780 SMART SM00486 168 572 3.4E-111 T 31-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DFR85_08845 ee88680c7aea0f443ba6ef608edd7510 780 Pfam PF03104 DNA polymerase family B, exonuclease domain 27 291 6.3E-46 T 31-10-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DFR85_08845 ee88680c7aea0f443ba6ef608edd7510 780 Gene3D G3DSA:3.30.420.10 142 375 3.8E-75 T 31-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 DFR85_08845 ee88680c7aea0f443ba6ef608edd7510 780 ProSitePatterns PS00116 DNA polymerase family B signature. 560 568 - T 31-10-2018 IPR017964 DNA-directed DNA polymerase, family B, conserved site GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DFR85_08845 ee88680c7aea0f443ba6ef608edd7510 780 Pfam PF00136 DNA polymerase family B 362 758 1.5E-71 T 31-10-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DFR85_06275 b7563113b3a8a1bcc2e2cb5bdfc2717d 130 Gene3D G3DSA:3.40.50.620 1 130 2.0E-31 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR85_06275 b7563113b3a8a1bcc2e2cb5bdfc2717d 130 SUPERFAMILY SSF52402 1 130 4.94E-30 T 31-10-2018 DFR85_06275 b7563113b3a8a1bcc2e2cb5bdfc2717d 130 Pfam PF00582 Universal stress protein family 2 130 1.4E-28 T 31-10-2018 IPR006016 UspA DFR85_06275 b7563113b3a8a1bcc2e2cb5bdfc2717d 130 PRINTS PR01438 Universal stress protein signature 90 102 1.7E-10 T 31-10-2018 IPR006015 Universal stress protein A DFR85_06275 b7563113b3a8a1bcc2e2cb5bdfc2717d 130 PRINTS PR01438 Universal stress protein signature 108 130 1.7E-10 T 31-10-2018 IPR006015 Universal stress protein A DFR85_07620 5cd1a5f179b097e8f594c73f581221c2 170 Gene3D G3DSA:3.30.428.10 1 169 6.1E-56 T 31-10-2018 IPR036265 HIT-like superfamily DFR85_07620 5cd1a5f179b097e8f594c73f581221c2 170 SUPERFAMILY SSF54197 1 161 4.18E-43 T 31-10-2018 IPR036265 HIT-like superfamily DFR85_07620 5cd1a5f179b097e8f594c73f581221c2 170 Pfam PF01230 HIT domain 38 128 2.2E-15 T 31-10-2018 IPR001310 Histidine triad (HIT) protein DFR85_02385 73a6bb1cccd59709c4721e0168e835cd 607 Pfam PF00723 Glycosyl hydrolases family 15 255 555 2.4E-16 T 31-10-2018 IPR011613 GH15-like domain Reactome: R-HSA-70221 DFR85_02385 73a6bb1cccd59709c4721e0168e835cd 607 Gene3D G3DSA:1.50.10.10 237 607 4.4E-86 T 31-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 DFR85_02385 73a6bb1cccd59709c4721e0168e835cd 607 SUPERFAMILY SSF48208 228 606 1.52E-92 T 31-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 DFR85_12100 2e31f7cf928a66c8dcf40707800bac4e 507 SMART SM00487 23 236 1.0E-10 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain DFR85_12100 2e31f7cf928a66c8dcf40707800bac4e 507 Gene3D G3DSA:3.40.50.300 235 390 2.6E-16 T 31-10-2018 DFR85_12100 2e31f7cf928a66c8dcf40707800bac4e 507 Pfam PF00271 Helicase conserved C-terminal domain 259 349 4.3E-10 T 31-10-2018 IPR001650 Helicase, C-terminal DFR85_12100 2e31f7cf928a66c8dcf40707800bac4e 507 Pfam PF00270 DEAD/DEAH box helicase 33 210 2.0E-11 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 DFR85_12100 2e31f7cf928a66c8dcf40707800bac4e 507 Gene3D G3DSA:3.40.50.300 19 218 2.8E-17 T 31-10-2018 DFR85_12100 2e31f7cf928a66c8dcf40707800bac4e 507 SMART SM00490 273 349 2.1E-6 T 31-10-2018 IPR001650 Helicase, C-terminal DFR85_12100 2e31f7cf928a66c8dcf40707800bac4e 507 SUPERFAMILY SSF52540 36 361 6.1E-34 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_12100 2e31f7cf928a66c8dcf40707800bac4e 507 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 44 377 4.7E-60 T 31-10-2018 IPR006474 Helicase Cas3, CRISPR-associated, core DFR85_08855 b7935f9d6fb1ab0c82b711ef4470c9da 357 Gene3D G3DSA:3.40.50.620 1 209 1.7E-62 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR85_08855 b7935f9d6fb1ab0c82b711ef4470c9da 357 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 4 353 2.8E-42 T 31-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 DFR85_08855 b7935f9d6fb1ab0c82b711ef4470c9da 357 Hamap MF_02009 Tyrosine--tRNA ligase [tyrS]. 3 340 46.916 T 31-10-2018 IPR023678 Tyrosine-tRNA ligase, type 4 GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 DFR85_08855 b7935f9d6fb1ab0c82b711ef4470c9da 357 SUPERFAMILY SSF52374 4 342 3.9E-68 T 31-10-2018 DFR85_08855 b7935f9d6fb1ab0c82b711ef4470c9da 357 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 169 191 2.0E-12 T 31-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 DFR85_08855 b7935f9d6fb1ab0c82b711ef4470c9da 357 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 42 64 2.0E-12 T 31-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 DFR85_08855 b7935f9d6fb1ab0c82b711ef4470c9da 357 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 152 167 2.0E-12 T 31-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 DFR85_08855 b7935f9d6fb1ab0c82b711ef4470c9da 357 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 202 214 2.0E-12 T 31-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 DFR85_08855 b7935f9d6fb1ab0c82b711ef4470c9da 357 Pfam PF00579 tRNA synthetases class I (W and Y) 28 333 2.2E-46 T 31-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR85_08855 b7935f9d6fb1ab0c82b711ef4470c9da 357 Gene3D G3DSA:1.10.240.10 210 357 1.7E-45 T 31-10-2018 DFR85_08855 b7935f9d6fb1ab0c82b711ef4470c9da 357 PIRSF PIRSF006588 1 357 1.8E-126 T 31-10-2018 IPR023617 Tyrosine-tRNA ligase, archaeal/eukaryotic-type GO:0004831 KEGG: 00970+6.1.1.1 DFR85_10740 8b45036c6d8a0d28106c76c5f14671cc 441 TIGRFAM TIGR02153 gatD_arch: glutamyl-tRNA(Gln) amidotransferase, subunit D 34 431 6.7E-178 T 31-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 DFR85_10740 8b45036c6d8a0d28106c76c5f14671cc 441 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 168 178 - T 31-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 DFR85_10740 8b45036c6d8a0d28106c76c5f14671cc 441 Gene3D G3DSA:3.40.50.40 299 437 6.6E-49 T 31-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 DFR85_10740 8b45036c6d8a0d28106c76c5f14671cc 441 TIGRFAM TIGR00519 asnASE_I: L-asparaginase, type I 89 427 6.8E-123 T 31-10-2018 IPR006033 L-asparaginase, type I GO:0004067|GO:0006520 Reactome: R-HSA-70614 DFR85_10740 8b45036c6d8a0d28106c76c5f14671cc 441 PRINTS PR00139 Asparaginase/glutaminase family signature 91 102 8.0E-15 T 31-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 DFR85_10740 8b45036c6d8a0d28106c76c5f14671cc 441 PRINTS PR00139 Asparaginase/glutaminase family signature 167 185 8.0E-15 T 31-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 DFR85_10740 8b45036c6d8a0d28106c76c5f14671cc 441 PRINTS PR00139 Asparaginase/glutaminase family signature 352 370 8.0E-15 T 31-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 DFR85_10740 8b45036c6d8a0d28106c76c5f14671cc 441 Hamap MF_00586 Glutamyl-tRNA(Gln) amidotransferase subunit D [gatD]. 25 431 46.204 T 31-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 DFR85_10740 8b45036c6d8a0d28106c76c5f14671cc 441 SUPERFAMILY SSF141300 5 72 1.31E-18 T 31-10-2018 IPR037222 GatD, N-terminal DFR85_10740 8b45036c6d8a0d28106c76c5f14671cc 441 Pfam PF00710 Asparaginase, N-terminal 91 281 1.5E-60 T 31-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 DFR85_10740 8b45036c6d8a0d28106c76c5f14671cc 441 Gene3D G3DSA:3.40.50.1170 84 298 7.9E-72 T 31-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 DFR85_10740 8b45036c6d8a0d28106c76c5f14671cc 441 SMART SM00870 90 415 3.8E-135 T 31-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 DFR85_10740 8b45036c6d8a0d28106c76c5f14671cc 441 Gene3D G3DSA:2.30.30.520 4 83 5.1E-22 T 31-10-2018 IPR037222 GatD, N-terminal DFR85_10740 8b45036c6d8a0d28106c76c5f14671cc 441 PIRSF PIRSF500175 19 435 7.3E-178 T 31-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 DFR85_10740 8b45036c6d8a0d28106c76c5f14671cc 441 SUPERFAMILY SSF53774 80 434 2.09E-107 T 31-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 DFR85_10740 8b45036c6d8a0d28106c76c5f14671cc 441 PIRSF PIRSF001220 85 426 1.5E-121 T 31-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 DFR85_08025 4bdc8c6ef2a6e5ecb004277df9c4c942 217 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 119 131 - T 31-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 DFR85_08025 4bdc8c6ef2a6e5ecb004277df9c4c942 217 Gene3D G3DSA:3.30.200.20 12 84 3.0E-22 T 31-10-2018 DFR85_08025 4bdc8c6ef2a6e5ecb004277df9c4c942 217 Gene3D G3DSA:1.10.510.10 90 209 1.3E-27 T 31-10-2018 DFR85_08025 4bdc8c6ef2a6e5ecb004277df9c4c942 217 SUPERFAMILY SSF56112 2 170 5.8E-23 T 31-10-2018 IPR011009 Protein kinase-like domain superfamily DFR85_08025 4bdc8c6ef2a6e5ecb004277df9c4c942 217 TIGRFAM TIGR03724 arch_bud32: Kae1-associated kinase Bud32 7 208 6.9E-73 T 31-10-2018 IPR022495 Serine/threonine-protein kinase Bud32 GO:0004674 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6782315|Reactome: R-HSA-6804756 DFR85_08025 4bdc8c6ef2a6e5ecb004277df9c4c942 217 Pfam PF00069 Protein kinase domain 28 151 1.6E-9 T 31-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DFR85_14200 d383ca05675acda6aa5f8bf21c18c16d 416 SUPERFAMILY SSF52833 5 94 8.36E-15 T 31-10-2018 IPR036249 Thioredoxin-like superfamily DFR85_14200 d383ca05675acda6aa5f8bf21c18c16d 416 SUPERFAMILY SSF48208 137 300 1.36E-12 T 31-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 DFR85_14200 d383ca05675acda6aa5f8bf21c18c16d 416 Gene3D G3DSA:3.40.30.10 2 97 8.6E-12 T 31-10-2018 DFR85_14200 d383ca05675acda6aa5f8bf21c18c16d 416 ProSitePatterns PS00194 Thioredoxin family active site. 18 36 - T 31-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 DFR85_14200 d383ca05675acda6aa5f8bf21c18c16d 416 Pfam PF00085 Thioredoxin 4 95 2.0E-7 T 31-10-2018 IPR013766 Thioredoxin domain GO:0045454 DFR85_14710 48fed24997afc65fae1080c8f8cda50b 384 Gene3D G3DSA:3.50.50.60 118 262 6.0E-88 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_14710 48fed24997afc65fae1080c8f8cda50b 384 SUPERFAMILY SSF51905 122 253 1.48E-31 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_14710 48fed24997afc65fae1080c8f8cda50b 384 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 314 2.5E-9 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR85_14710 48fed24997afc65fae1080c8f8cda50b 384 Gene3D G3DSA:3.50.50.60 4 318 6.0E-88 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_14710 48fed24997afc65fae1080c8f8cda50b 384 SUPERFAMILY SSF51905 1 154 1.69E-18 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_12490 882c4392b8b6d62071c38862b61fe398 376 Pfam PF01546 Peptidase family M20/M25/M40 68 371 5.4E-30 T 31-10-2018 IPR002933 Peptidase M20 GO:0016787 DFR85_12490 882c4392b8b6d62071c38862b61fe398 376 Gene3D G3DSA:3.40.630.10 7 361 2.5E-84 T 31-10-2018 DFR85_12490 882c4392b8b6d62071c38862b61fe398 376 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 6 361 3.0E-92 T 31-10-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase DFR85_12490 882c4392b8b6d62071c38862b61fe398 376 SUPERFAMILY SSF53187 6 371 1.56E-50 T 31-10-2018 DFR85_12490 882c4392b8b6d62071c38862b61fe398 376 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 103 139 - T 31-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 DFR85_12490 882c4392b8b6d62071c38862b61fe398 376 SUPERFAMILY SSF55031 171 289 4.34E-17 T 31-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain DFR85_12490 882c4392b8b6d62071c38862b61fe398 376 Gene3D G3DSA:3.30.70.360 172 299 2.5E-84 T 31-10-2018 DFR85_12490 882c4392b8b6d62071c38862b61fe398 376 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 67 76 - T 31-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 DFR85_12490 882c4392b8b6d62071c38862b61fe398 376 Pfam PF07687 Peptidase dimerisation domain 168 288 2.8E-20 T 31-10-2018 IPR011650 Peptidase M20, dimerisation domain DFR85_08095 02af980a0b041628f89cd531a21d1814 49 SMART SM00659 4 49 1.0E-12 T 31-10-2018 IPR006591 RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 DFR85_08095 02af980a0b041628f89cd531a21d1814 49 SUPERFAMILY SSF63393 4 48 1.78E-11 T 31-10-2018 IPR029040 RNA polymerase subunit RPABC4/transcription elongation factor Spt4 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 DFR85_08095 02af980a0b041628f89cd531a21d1814 49 Hamap MF_00615 DNA-directed RNA polymerase subunit P [rpoP]. 5 49 14.321 T 31-10-2018 IPR023464 DNA-directed RNA polymerase subunit P (Rpo12) GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR85_08095 02af980a0b041628f89cd531a21d1814 49 Gene3D G3DSA:2.20.28.30 3 49 1.4E-18 T 31-10-2018 DFR85_10485 3be65d7eae4a2fa958ed111ae6dc7505 368 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 134 269 2.5E-38 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 DFR85_10485 3be65d7eae4a2fa958ed111ae6dc7505 368 SUPERFAMILY SSF116846 8 83 8.89E-15 T 31-10-2018 IPR036181 MIT domain superfamily DFR85_10485 3be65d7eae4a2fa958ed111ae6dc7505 368 Pfam PF04212 MIT (microtubule interacting and transport) domain 11 72 3.5E-11 T 31-10-2018 IPR007330 MIT DFR85_10485 3be65d7eae4a2fa958ed111ae6dc7505 368 Gene3D G3DSA:1.20.58.280 1 82 1.9E-29 T 31-10-2018 DFR85_10485 3be65d7eae4a2fa958ed111ae6dc7505 368 SMART SM00745 4 82 7.3E-16 T 31-10-2018 IPR007330 MIT DFR85_10485 3be65d7eae4a2fa958ed111ae6dc7505 368 SMART SM00382 130 271 6.7E-16 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_10485 3be65d7eae4a2fa958ed111ae6dc7505 368 Gene3D G3DSA:1.10.8.60 270 368 1.4E-19 T 31-10-2018 DFR85_10485 3be65d7eae4a2fa958ed111ae6dc7505 368 SUPERFAMILY SSF52540 95 365 4.25E-60 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_10485 3be65d7eae4a2fa958ed111ae6dc7505 368 Gene3D G3DSA:3.40.50.300 88 269 2.1E-65 T 31-10-2018 DFR85_10135 e2d065a8ee5c9002605793eaa60bd559 87 SUPERFAMILY SSF54575 4 82 5.49E-16 T 31-10-2018 IPR023621 Ribosomal protein L31e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_10135 e2d065a8ee5c9002605793eaa60bd559 87 SMART SM01380 2 78 5.5E-10 T 31-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_10135 e2d065a8ee5c9002605793eaa60bd559 87 Gene3D G3DSA:3.10.440.10 1 85 1.8E-10 T 31-10-2018 IPR023621 Ribosomal protein L31e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_10135 e2d065a8ee5c9002605793eaa60bd559 87 ProDom PD006030 RIBOSOMAL 60S L31 RIBONUCLEOPROTEIN L31E 50S L31 SUBUNIT STRAIN PHOSPHORYLATION 10 51 0.005 T 31-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_10070 71b3d8698eb2855f35f5dc581ba1c06c 349 Gene3D G3DSA:3.40.350.10 1 126 2.3E-10 T 31-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal DFR85_10070 71b3d8698eb2855f35f5dc581ba1c06c 349 Pfam PF00557 Metallopeptidase family M24 134 335 1.5E-68 T 31-10-2018 IPR000994 Peptidase M24 DFR85_10070 71b3d8698eb2855f35f5dc581ba1c06c 349 Pfam PF01321 Creatinase/Prolidase N-terminal domain 17 126 5.4E-7 T 31-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 DFR85_10070 71b3d8698eb2855f35f5dc581ba1c06c 349 SUPERFAMILY SSF53092 17 126 2.27E-9 T 31-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal DFR85_10070 71b3d8698eb2855f35f5dc581ba1c06c 349 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 282 294 - T 31-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site DFR85_10070 71b3d8698eb2855f35f5dc581ba1c06c 349 SUPERFAMILY SSF55920 126 342 1.44E-73 T 31-10-2018 IPR036005 Creatinase/aminopeptidase-like DFR85_10070 71b3d8698eb2855f35f5dc581ba1c06c 349 Gene3D G3DSA:3.90.230.10 127 349 9.4E-81 T 31-10-2018 DFR85_11415 baeeb980b7bbd959cd0cea5f2a9e0b29 139 SUPERFAMILY SSF75169 5 135 9.42E-22 T 31-10-2018 IPR027396 DsrEFH-like DFR85_11415 baeeb980b7bbd959cd0cea5f2a9e0b29 139 Pfam PF13686 DsrE/DsrF/DrsH-like family 4 135 1.5E-27 T 31-10-2018 IPR032836 DsrE2-like family DFR85_11415 baeeb980b7bbd959cd0cea5f2a9e0b29 139 Gene3D G3DSA:3.40.1260.10 1 139 5.4E-53 T 31-10-2018 IPR027396 DsrEFH-like DFR85_13930 e32219c0fecf1c951338020cec47fbf3 464 Gene3D G3DSA:3.90.650.10 226 457 1.9E-19 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily DFR85_13930 e32219c0fecf1c951338020cec47fbf3 464 SUPERFAMILY SSF56042 260 442 7.85E-11 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily DFR85_13930 e32219c0fecf1c951338020cec47fbf3 464 Pfam PF02769 AIR synthase related protein, C-terminal domain 339 444 2.0E-8 T 31-10-2018 IPR010918 PurM-like, C-terminal domain DFR85_09690 cc45a8b63d40d2ead4b024a37824616c 352 Pfam PF00146 NADH dehydrogenase 26 342 6.6E-78 T 31-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_09690 cc45a8b63d40d2ead4b024a37824616c 352 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 15 350 18.051 T 31-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_02605 e0b05309b0fab89f5f9a3affc7ca1d73 399 Pfam PF07690 Major Facilitator Superfamily 21 346 3.3E-24 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_02605 e0b05309b0fab89f5f9a3affc7ca1d73 399 Gene3D G3DSA:1.20.1250.20 3 197 3.3E-27 T 31-10-2018 DFR85_02605 e0b05309b0fab89f5f9a3affc7ca1d73 399 SUPERFAMILY SSF103473 10 387 1.44E-47 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_02605 e0b05309b0fab89f5f9a3affc7ca1d73 399 Gene3D G3DSA:1.20.1250.20 203 393 1.2E-10 T 31-10-2018 DFR85_13880 9c1f1754eed97a51b0899776062df918 401 Gene3D G3DSA:3.40.50.970 2 246 1.4E-93 T 31-10-2018 DFR85_13880 9c1f1754eed97a51b0899776062df918 401 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 262 360 5.4E-25 T 31-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II DFR85_13880 9c1f1754eed97a51b0899776062df918 401 SUPERFAMILY SSF52922 257 375 1.22E-28 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 DFR85_13880 9c1f1754eed97a51b0899776062df918 401 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 16 237 5.4E-67 T 31-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 DFR85_13880 9c1f1754eed97a51b0899776062df918 401 Gene3D G3DSA:3.40.50.920 255 385 1.5E-31 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 DFR85_13880 9c1f1754eed97a51b0899776062df918 401 SUPERFAMILY SSF52518 1 244 1.36E-64 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR85_01035 aa772b95c440d124b4d9f51cf07e1100 443 Gene3D G3DSA:3.40.50.300 233 430 1.1E-47 T 31-10-2018 DFR85_01035 aa772b95c440d124b4d9f51cf07e1100 443 SMART SM00490 335 414 1.0E-15 T 31-10-2018 IPR001650 Helicase, C-terminal DFR85_01035 aa772b95c440d124b4d9f51cf07e1100 443 Gene3D G3DSA:3.40.50.300 57 232 1.2E-45 T 31-10-2018 DFR85_01035 aa772b95c440d124b4d9f51cf07e1100 443 Pfam PF16203 ERCC3/RAD25/XPB C-terminal helicase 320 439 1.4E-19 T 31-10-2018 IPR032438 ERCC3/RAD25/XPB helicase, C-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 DFR85_01035 aa772b95c440d124b4d9f51cf07e1100 443 SUPERFAMILY SSF52540 47 309 6.38E-5 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_01035 aa772b95c440d124b4d9f51cf07e1100 443 SUPERFAMILY SSF52540 109 434 1.39E-44 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_01035 aa772b95c440d124b4d9f51cf07e1100 443 SMART SM00487 65 237 2.8E-28 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain DFR85_01035 aa772b95c440d124b4d9f51cf07e1100 443 Pfam PF04851 Type III restriction enzyme, res subunit 67 205 1.5E-24 T 31-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 DFR85_04965 f58fea9f02ae903d046c44bc78daad23 298 Pfam PF00535 Glycosyl transferase family 2 5 170 3.7E-34 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 DFR85_04965 f58fea9f02ae903d046c44bc78daad23 298 Gene3D G3DSA:3.90.550.10 1 221 4.4E-48 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_04965 f58fea9f02ae903d046c44bc78daad23 298 SUPERFAMILY SSF53448 1 270 1.99E-50 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_02140 f6c266eea26da791b738702e4bca5af6 653 Pfam PF01968 Hydantoinase/oxoprolinase 193 482 1.7E-93 T 31-10-2018 IPR002821 Hydantoinase A/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 DFR85_02140 f6c266eea26da791b738702e4bca5af6 653 SUPERFAMILY SSF53067 3 337 4.6E-7 T 31-10-2018 DFR85_02140 f6c266eea26da791b738702e4bca5af6 653 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 3 174 8.4E-49 T 31-10-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 DFR85_00995 5d86d124abd5e1848b02968e05a4483e 432 Gene3D G3DSA:1.20.1740.10 27 432 1.5E-10 T 31-10-2018 DFR85_00995 5d86d124abd5e1848b02968e05a4483e 432 PIRSF PIRSF006060 2 323 1.5E-18 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_00995 5d86d124abd5e1848b02968e05a4483e 432 PIRSF PIRSF006060 316 432 0.67 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_02020 4f22a9ab8181fcc1e0809fa595a1a94f 191 SUPERFAMILY SSF53474 3 188 5.63E-20 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold DFR85_02020 4f22a9ab8181fcc1e0809fa595a1a94f 191 Pfam PF00326 Prolyl oligopeptidase family 52 166 6.4E-9 T 31-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 DFR85_02020 4f22a9ab8181fcc1e0809fa595a1a94f 191 Gene3D G3DSA:3.40.50.1820 3 190 1.9E-19 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold DFR85_01715 bd6d0506ce03d403397cd2d3d98c93e2 191 Gene3D G3DSA:3.40.50.1390 56 150 6.9E-25 T 31-10-2018 DFR85_01715 bd6d0506ce03d403397cd2d3d98c93e2 191 SMART SM00857 56 187 4.2E-15 T 31-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 DFR85_01715 bd6d0506ce03d403397cd2d3d98c93e2 191 Pfam PF00239 Resolvase, N terminal domain 56 181 1.1E-15 T 31-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 DFR85_01715 bd6d0506ce03d403397cd2d3d98c93e2 191 Pfam PF12728 Helix-turn-helix domain 1 48 3.7E-10 T 31-10-2018 DFR85_01715 bd6d0506ce03d403397cd2d3d98c93e2 191 Gene3D G3DSA:1.10.1660.10 1 55 7.9E-9 T 31-10-2018 DFR85_01715 bd6d0506ce03d403397cd2d3d98c93e2 191 ProSitePatterns PS00397 Site-specific recombinases active site. 59 67 - T 31-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 DFR85_01715 bd6d0506ce03d403397cd2d3d98c93e2 191 SUPERFAMILY SSF53041 54 178 1.83E-18 T 31-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 DFR85_01715 bd6d0506ce03d403397cd2d3d98c93e2 191 SUPERFAMILY SSF46955 1 54 1.28E-10 T 31-10-2018 IPR009061 Putative DNA-binding domain superfamily DFR85_01580 389b9b02ab83d1038c68c3345cd647f5 1078 SUPERFAMILY SSF52743 170 509 1.3E-59 T 31-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 DFR85_01580 389b9b02ab83d1038c68c3345cd647f5 1078 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 437 447 - T 31-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site DFR85_01580 389b9b02ab83d1038c68c3345cd647f5 1078 PIRSF PIRSF032623 1 1073 9.7E-267 T 31-10-2018 IPR017001 Peptidase S53, physarolisin II, archaeal-type DFR85_01580 389b9b02ab83d1038c68c3345cd647f5 1078 SUPERFAMILY SSF54897 27 139 8.33E-5 T 31-10-2018 DFR85_01580 389b9b02ab83d1038c68c3345cd647f5 1078 Gene3D G3DSA:3.40.50.200 164 514 1.1E-76 T 31-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 DFR85_01580 389b9b02ab83d1038c68c3345cd647f5 1078 Pfam PF09286 Pro-kumamolisin, activation domain 29 129 2.1E-7 T 31-10-2018 IPR015366 Peptidase S53, activation domain GO:0008236 Reactome: R-HSA-381038 DFR85_01580 389b9b02ab83d1038c68c3345cd647f5 1078 SMART SM00944 23 147 2.9E-12 T 31-10-2018 IPR015366 Peptidase S53, activation domain GO:0008236 Reactome: R-HSA-381038 DFR85_02460 3ccc397d90d3a339996fb4fb76897652 412 Gene3D G3DSA:3.30.420.40 1 107 1.1E-18 T 31-10-2018 DFR85_02460 3ccc397d90d3a339996fb4fb76897652 412 Gene3D G3DSA:3.30.420.150 108 287 2.1E-46 T 31-10-2018 DFR85_02460 3ccc397d90d3a339996fb4fb76897652 412 SUPERFAMILY SSF53067 3 124 2.04E-26 T 31-10-2018 DFR85_02460 3ccc397d90d3a339996fb4fb76897652 412 Pfam PF02541 Ppx/GppA phosphatase family 24 287 4.9E-46 T 31-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 DFR85_02460 3ccc397d90d3a339996fb4fb76897652 412 SUPERFAMILY SSF53067 126 287 2.07E-35 T 31-10-2018 DFR85_09345 ef03c002bb5937c1749ca734ac9c6889 218 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 4 196 6.1E-23 T 31-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 DFR85_09345 ef03c002bb5937c1749ca734ac9c6889 218 Hamap MF_01200_A Orotidine 5'-phosphate decarboxylase [pyrF]. 4 211 32.573 T 31-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 DFR85_09345 ef03c002bb5937c1749ca734ac9c6889 218 SMART SM00934 3 201 6.6E-35 T 31-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 DFR85_09345 ef03c002bb5937c1749ca734ac9c6889 218 Gene3D G3DSA:3.20.20.70 2 218 7.6E-56 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_09345 ef03c002bb5937c1749ca734ac9c6889 218 SUPERFAMILY SSF51366 2 208 2.48E-41 T 31-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 DFR85_09345 ef03c002bb5937c1749ca734ac9c6889 218 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 15 195 6.4E-30 T 31-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 DFR85_09345 ef03c002bb5937c1749ca734ac9c6889 218 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 53 66 - T 31-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 DFR85_08325 bb4874413353aeb58723039e70e52f47 179 Pfam PF05916 GINS complex protein 45 156 8.9E-9 T 31-10-2018 IPR021151 GINS subunit, domain A Reactome: R-HSA-176974 DFR85_08325 bb4874413353aeb58723039e70e52f47 179 Gene3D G3DSA:1.20.58.2050 43 174 4.0E-7 T 31-10-2018 IPR038437 GINS complex, subunit Psf3 superfamily Reactome: R-HSA-176974 DFR85_08065 b9feb96fa3a6a453262369bd9c0dc1d7 182 Gene3D G3DSA:3.40.1350.10 88 182 8.5E-31 T 31-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 DFR85_08065 b9feb96fa3a6a453262369bd9c0dc1d7 182 Hamap MF_01833 tRNA-splicing endonuclease [endA]. 3 182 31.531 T 31-10-2018 IPR016442 tRNA-splicing endonuclease, archaeal short subfamily MetaCyc: PWY-6689|MetaCyc: PWY-7803 DFR85_08065 b9feb96fa3a6a453262369bd9c0dc1d7 182 TIGRFAM TIGR00324 endA: tRNA-intron lyase 45 180 4.0E-30 T 31-10-2018 IPR006676 tRNA-splicing endonuclease GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 DFR85_08065 b9feb96fa3a6a453262369bd9c0dc1d7 182 PIRSF PIRSF005285 6 182 4.1E-56 T 31-10-2018 IPR016442 tRNA-splicing endonuclease, archaeal short subfamily MetaCyc: PWY-6689|MetaCyc: PWY-7803 DFR85_08065 b9feb96fa3a6a453262369bd9c0dc1d7 182 SUPERFAMILY SSF53032 88 170 5.06E-24 T 31-10-2018 IPR036167 tRNA intron endonuclease, catalytic domain-like superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 DFR85_08065 b9feb96fa3a6a453262369bd9c0dc1d7 182 SUPERFAMILY SSF55267 6 83 1.79E-12 T 31-10-2018 IPR036740 tRNA intron endonuclease, N-terminal domain superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803 DFR85_08065 b9feb96fa3a6a453262369bd9c0dc1d7 182 Gene3D G3DSA:3.40.1170.20 4 87 2.3E-23 T 31-10-2018 DFR85_08065 b9feb96fa3a6a453262369bd9c0dc1d7 182 Pfam PF01974 tRNA intron endonuclease, catalytic C-terminal domain 89 167 1.1E-25 T 31-10-2018 IPR006677 tRNA intron endonuclease, catalytic domain-like GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 DFR85_08065 b9feb96fa3a6a453262369bd9c0dc1d7 182 Pfam PF02778 tRNA intron endonuclease, N-terminal domain 5 78 2.8E-14 T 31-10-2018 IPR006678 tRNA intron endonuclease, N-terminal GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 DFR85_03675 226a98965db3542fd1dee869bfa1ffc0 113 Gene3D G3DSA:2.40.30.70 1 105 6.3E-22 T 31-10-2018 IPR036414 YaeB, N-terminal domain superfamily DFR85_03675 226a98965db3542fd1dee869bfa1ffc0 113 Pfam PF01980 Uncharacterised protein family UPF0066 34 88 4.4E-20 T 31-10-2018 IPR023370 YaeB-like, N-terminal domain DFR85_03675 226a98965db3542fd1dee869bfa1ffc0 113 SUPERFAMILY SSF118196 34 106 1.31E-23 T 31-10-2018 IPR036413 YaeB-like superfamily DFR85_06345 0f5014bcdd7a9b6853a6feec1178c2ac 404 Pfam PF08543 Phosphomethylpyrimidine kinase 14 254 4.6E-82 T 31-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 DFR85_06345 0f5014bcdd7a9b6853a6feec1178c2ac 404 Gene3D G3DSA:3.40.1190.20 1 274 6.5E-87 T 31-10-2018 IPR029056 Ribokinase-like DFR85_06345 0f5014bcdd7a9b6853a6feec1178c2ac 404 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 203 216 - T 31-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 DFR85_06345 0f5014bcdd7a9b6853a6feec1178c2ac 404 SUPERFAMILY SSF53613 5 259 4.21E-71 T 31-10-2018 IPR029056 Ribokinase-like DFR85_06345 0f5014bcdd7a9b6853a6feec1178c2ac 404 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 7 255 4.0E-93 T 31-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 DFR85_06345 0f5014bcdd7a9b6853a6feec1178c2ac 404 SUPERFAMILY SSF53639 273 401 5.49E-5 T 31-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily DFR85_08875 e0cad8b9312dc3377802b823a49cabe6 173 SUPERFAMILY SSF46946 10 147 2.47E-32 T 31-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 DFR85_08875 e0cad8b9312dc3377802b823a49cabe6 173 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 9 149 24.017 T 31-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_08875 e0cad8b9312dc3377802b823a49cabe6 173 TIGRFAM TIGR03629 uS13_arch: ribosomal protein uS13 5 147 2.3E-56 T 31-10-2018 IPR019977 Ribosomal protein S13, archaeal GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_08875 e0cad8b9312dc3377802b823a49cabe6 173 PIRSF PIRSF002134 2 153 1.2E-41 T 31-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_08875 e0cad8b9312dc3377802b823a49cabe6 173 ProSitePatterns PS00646 Ribosomal protein S13 signature. 118 131 - T 31-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_08875 e0cad8b9312dc3377802b823a49cabe6 173 Pfam PF00416 Ribosomal protein S13/S18 11 138 3.9E-46 T 31-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_08875 e0cad8b9312dc3377802b823a49cabe6 173 Gene3D G3DSA:1.10.8.50 1 77 1.0E-22 T 31-10-2018 DFR85_08875 e0cad8b9312dc3377802b823a49cabe6 173 Gene3D G3DSA:4.10.910.10 89 139 3.3E-20 T 31-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_15065 2aea2eeb2f598011d6dd1f9491f5dc20 356 SUPERFAMILY SSF52540 3 281 5.45E-50 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_15065 2aea2eeb2f598011d6dd1f9491f5dc20 356 Gene3D G3DSA:1.10.8.60 207 284 4.0E-28 T 31-10-2018 DFR85_15065 2aea2eeb2f598011d6dd1f9491f5dc20 356 SUPERFAMILY SSF46785 288 355 2.23E-13 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_15065 2aea2eeb2f598011d6dd1f9491f5dc20 356 Gene3D G3DSA:3.40.50.300 1 206 5.3E-52 T 31-10-2018 DFR85_15065 2aea2eeb2f598011d6dd1f9491f5dc20 356 Pfam PF01637 ATPase domain predominantly from Archaea 14 247 7.0E-26 T 31-10-2018 IPR011579 ATPase domain GO:0005524 DFR85_15065 2aea2eeb2f598011d6dd1f9491f5dc20 356 Gene3D G3DSA:1.10.10.10 285 356 4.4E-30 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_09935 ba4636e68044b668362da83efda40832 117 SMART SM01407 6 63 1.1E-10 T 31-10-2018 IPR002715 Nascent polypeptide-associated complex NAC domain DFR85_09935 ba4636e68044b668362da83efda40832 117 Gene3D G3DSA:2.20.70.30 9 69 2.1E-10 T 31-10-2018 IPR038187 NAC A/B domain superfamily DFR85_09935 ba4636e68044b668362da83efda40832 117 Gene3D G3DSA:1.10.8.10 73 112 7.2E-17 T 31-10-2018 DFR85_09935 ba4636e68044b668362da83efda40832 117 Pfam PF01849 NAC domain 10 61 5.5E-7 T 31-10-2018 IPR002715 Nascent polypeptide-associated complex NAC domain DFR85_09935 ba4636e68044b668362da83efda40832 117 Hamap MF_00814 Nascent polypeptide-associated complex protein [nac]. 7 112 18.175 T 31-10-2018 IPR005231 Nascent polypeptide-associated complex (NAC), archaeal GO:0003723 DFR85_09935 ba4636e68044b668362da83efda40832 117 SUPERFAMILY SSF46934 68 113 6.24E-9 T 31-10-2018 IPR009060 UBA-like superfamily GO:0005515 DFR85_09495 cab10735a2c7fc61cc29d2ae1c14438d 123 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 9 122 27.402 T 31-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 DFR85_09495 cab10735a2c7fc61cc29d2ae1c14438d 123 SUPERFAMILY SSF56276 11 119 1.06E-32 T 31-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 DFR85_09495 cab10735a2c7fc61cc29d2ae1c14438d 123 Gene3D G3DSA:3.60.90.10 3 122 7.1E-35 T 31-10-2018 DFR85_09495 cab10735a2c7fc61cc29d2ae1c14438d 123 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 10 120 2.5E-37 T 31-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 DFR85_09495 cab10735a2c7fc61cc29d2ae1c14438d 123 Pfam PF02675 S-adenosylmethionine decarboxylase 17 119 3.0E-33 T 31-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 DFR85_14555 db2c32ccf48c8ab33ad8e49b2a755d85 139 SUPERFAMILY SSF46785 11 138 1.77E-30 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_14555 db2c32ccf48c8ab33ad8e49b2a755d85 139 SMART SM00347 25 126 8.2E-20 T 31-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DFR85_14555 db2c32ccf48c8ab33ad8e49b2a755d85 139 Pfam PF01047 MarR family 50 90 6.7E-12 T 31-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DFR85_14555 db2c32ccf48c8ab33ad8e49b2a755d85 139 ProSitePatterns PS01117 MarR-type HTH domain signature. 65 99 - T 31-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site DFR85_14555 db2c32ccf48c8ab33ad8e49b2a755d85 139 Gene3D G3DSA:1.10.10.10 1 139 7.3E-32 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_14555 db2c32ccf48c8ab33ad8e49b2a755d85 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 116 136 4.5E-17 T 31-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DFR85_14555 db2c32ccf48c8ab33ad8e49b2a755d85 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 102 4.5E-17 T 31-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DFR85_14555 db2c32ccf48c8ab33ad8e49b2a755d85 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 82 4.5E-17 T 31-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DFR85_14555 db2c32ccf48c8ab33ad8e49b2a755d85 139 PRINTS PR00598 Bacterial regulatory protein MarR family signature 50 66 4.5E-17 T 31-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DFR85_06720 1ea503ce0b7d2951b248265f74942c75 424 Gene3D G3DSA:3.90.1150.10 14 414 1.5E-152 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 DFR85_06720 1ea503ce0b7d2951b248265f74942c75 424 Pfam PF00202 Aminotransferase class-III 37 377 6.4E-64 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DFR85_06720 1ea503ce0b7d2951b248265f74942c75 424 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 9 423 85.974 T 31-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 DFR85_06720 1ea503ce0b7d2951b248265f74942c75 424 Gene3D G3DSA:3.40.640.10 73 319 1.5E-152 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR85_06720 1ea503ce0b7d2951b248265f74942c75 424 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 236 272 - T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DFR85_06720 1ea503ce0b7d2951b248265f74942c75 424 SUPERFAMILY SSF53383 9 422 1.57E-110 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase DFR85_06720 1ea503ce0b7d2951b248265f74942c75 424 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 11 422 9.5E-163 T 31-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 DFR85_09640 feb3988781c8322c16587ffd4569564f 142 PIRSF PIRSF032756 1 142 2.8E-56 T 31-10-2018 IPR017006 Uncharacterised conserved protein UCP032756 DFR85_09640 feb3988781c8322c16587ffd4569564f 142 Pfam PF10051 Uncharacterized protein conserved in archaea (DUF2286) 2 136 7.4E-51 T 31-10-2018 IPR017006 Uncharacterised conserved protein UCP032756 DFR85_12555 7333016da1e7a8847d80af9d4cb793b5 331 Gene3D G3DSA:1.10.3730.40 184 330 4.0E-34 T 31-10-2018 DFR85_12555 7333016da1e7a8847d80af9d4cb793b5 331 SUPERFAMILY SSF51735 8 172 1.83E-44 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_12555 7333016da1e7a8847d80af9d4cb793b5 331 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 13 172 4.2E-53 T 31-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 DFR85_12555 7333016da1e7a8847d80af9d4cb793b5 331 SUPERFAMILY SSF48179 185 316 4.76E-18 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 DFR85_12555 7333016da1e7a8847d80af9d4cb793b5 331 Gene3D G3DSA:3.40.50.720 5 178 7.3E-52 T 31-10-2018 DFR85_12555 7333016da1e7a8847d80af9d4cb793b5 331 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 185 320 1.1E-24 T 31-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 DFR85_14895 43b12670146cac9be05ee72172c7db23 279 Gene3D G3DSA:1.10.600.10 2 263 7.2E-56 T 31-10-2018 IPR008949 Isoprenoid synthase domain superfamily DFR85_14895 43b12670146cac9be05ee72172c7db23 279 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 147 172 - T 31-10-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 DFR85_14895 43b12670146cac9be05ee72172c7db23 279 SUPERFAMILY SSF48576 6 266 3.13E-57 T 31-10-2018 IPR008949 Isoprenoid synthase domain superfamily DFR85_14895 43b12670146cac9be05ee72172c7db23 279 Pfam PF00494 Squalene/phytoene synthase 10 253 4.2E-44 T 31-10-2018 DFR85_15530 8df87b81e1e0aa052615aab6e9181ac7 120 Pfam PF02635 DsrE/DsrF-like family 17 120 6.4E-9 T 31-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein DFR85_15530 8df87b81e1e0aa052615aab6e9181ac7 120 Gene3D G3DSA:3.40.1260.10 2 120 2.0E-22 T 31-10-2018 IPR027396 DsrEFH-like DFR85_15530 8df87b81e1e0aa052615aab6e9181ac7 120 SUPERFAMILY SSF75169 6 120 7.74E-18 T 31-10-2018 IPR027396 DsrEFH-like DFR85_12045 cf4cfdab4ed543eb3a8ec71a6c768392 279 Gene3D G3DSA:3.90.25.10 159 250 7.0E-83 T 31-10-2018 DFR85_12045 cf4cfdab4ed543eb3a8ec71a6c768392 279 Gene3D G3DSA:3.40.50.720 4 256 7.0E-83 T 31-10-2018 DFR85_12045 cf4cfdab4ed543eb3a8ec71a6c768392 279 SUPERFAMILY SSF51735 1 265 6.74E-66 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_12045 cf4cfdab4ed543eb3a8ec71a6c768392 279 Pfam PF04321 RmlD substrate binding domain 1 276 7.2E-62 T 31-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 DFR85_09150 ccf8f091f9e612b8f59977df2c9db0fc 220 SUPERFAMILY SSF56037 46 217 1.31E-33 T 31-10-2018 DFR85_09150 ccf8f091f9e612b8f59977df2c9db0fc 220 Pfam PF03483 B3/4 domain 59 210 7.8E-25 T 31-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 DFR85_09150 ccf8f091f9e612b8f59977df2c9db0fc 220 SMART SM00873 58 211 1.1E-21 T 31-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 DFR85_02040 d80fb2e7ec7cc0054c2d7b73d18b9068 460 Gene3D G3DSA:3.30.2130.30 1 169 2.6E-35 T 31-10-2018 DFR85_02040 d80fb2e7ec7cc0054c2d7b73d18b9068 460 SUPERFAMILY SSF52402 170 327 1.79E-35 T 31-10-2018 DFR85_02040 d80fb2e7ec7cc0054c2d7b73d18b9068 460 Gene3D G3DSA:3.40.50.620 170 378 9.5E-50 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR85_02040 d80fb2e7ec7cc0054c2d7b73d18b9068 460 SMART SM00981 72 160 8.4E-19 T 31-10-2018 IPR004114 THUMP domain GO:0003723 DFR85_02040 d80fb2e7ec7cc0054c2d7b73d18b9068 460 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 460 107.123 T 31-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 DFR85_02040 d80fb2e7ec7cc0054c2d7b73d18b9068 460 SUPERFAMILY SSF143437 1 168 2.27E-38 T 31-10-2018 DFR85_02040 d80fb2e7ec7cc0054c2d7b73d18b9068 460 Pfam PF02926 THUMP domain 37 155 2.6E-19 T 31-10-2018 IPR004114 THUMP domain GO:0003723 DFR85_02040 d80fb2e7ec7cc0054c2d7b73d18b9068 460 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 4 362 6.7E-85 T 31-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 DFR85_02040 d80fb2e7ec7cc0054c2d7b73d18b9068 460 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 170 361 6.1E-54 T 31-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 DFR85_09190 939c7d7444adc866ab9bc3335f57cb09 128 SUPERFAMILY SSF49464 61 114 7.06E-10 T 31-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily DFR85_09190 939c7d7444adc866ab9bc3335f57cb09 128 Gene3D G3DSA:2.60.40.1120 59 124 3.7E-5 T 31-10-2018 DFR85_02595 f0c5ade5bb5e09872fd173593e4ffcd1 326 SUPERFAMILY SSF141130 4 310 7.72E-78 T 31-10-2018 DFR85_02595 f0c5ade5bb5e09872fd173593e4ffcd1 326 Gene3D G3DSA:3.10.28.20 239 310 2.2E-5 T 31-10-2018 DFR85_02595 f0c5ade5bb5e09872fd173593e4ffcd1 326 Pfam PF03069 Acetamidase/Formamidase family 6 148 1.6E-25 T 31-10-2018 IPR004304 Acetamidase/Formamidase GO:0016811 DFR85_02595 f0c5ade5bb5e09872fd173593e4ffcd1 326 Pfam PF03069 Acetamidase/Formamidase family 156 311 8.6E-42 T 31-10-2018 IPR004304 Acetamidase/Formamidase GO:0016811 DFR85_02595 f0c5ade5bb5e09872fd173593e4ffcd1 326 Gene3D G3DSA:2.60.120.580 2 123 6.7E-19 T 31-10-2018 DFR85_02595 f0c5ade5bb5e09872fd173593e4ffcd1 326 Gene3D G3DSA:2.60.120.580 124 223 2.4E-30 T 31-10-2018 DFR85_09030 d56c52a4a3f52782ec4007989c271179 351 Pfam PF00534 Glycosyl transferases group 1 181 301 3.8E-17 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 DFR85_09030 d56c52a4a3f52782ec4007989c271179 351 SUPERFAMILY SSF53756 7 346 1.32E-32 T 31-10-2018 DFR85_09030 d56c52a4a3f52782ec4007989c271179 351 Gene3D G3DSA:3.40.50.2000 172 329 1.9E-22 T 31-10-2018 DFR85_09995 0f7c6a91b077fbc1b2454edf94a5ef76 172 Gene3D G3DSA:1.20.1200.10 23 172 3.9E-53 T 31-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 DFR85_09995 0f7c6a91b077fbc1b2454edf94a5ef76 172 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 9 169 1.0E-53 T 31-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 DFR85_09995 0f7c6a91b077fbc1b2454edf94a5ef76 172 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 4 170 4.3E-57 T 31-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 DFR85_09995 0f7c6a91b077fbc1b2454edf94a5ef76 172 SUPERFAMILY SSF89028 1 170 1.04E-49 T 31-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 DFR85_09995 0f7c6a91b077fbc1b2454edf94a5ef76 172 Pfam PF01923 Cobalamin adenosyltransferase 4 157 2.1E-45 T 31-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 DFR85_09100 19dedf4c4cb542d24a332e28153b93cc 395 Gene3D G3DSA:1.20.1250.20 8 368 1.9E-14 T 31-10-2018 DFR85_09100 19dedf4c4cb542d24a332e28153b93cc 395 Pfam PF05977 Transmembrane secretion effector 10 167 3.1E-6 T 31-10-2018 IPR010290 Transmembrane secretion effector DFR85_09100 19dedf4c4cb542d24a332e28153b93cc 395 SUPERFAMILY SSF103473 9 374 1.07E-22 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_08145 be2cf472723cad058e6246d362e2ccd8 822 SUPERFAMILY SSF82866 292 462 4.05E-20 T 31-10-2018 DFR85_08145 be2cf472723cad058e6246d362e2ccd8 822 SUPERFAMILY SSF82866 635 815 4.32E-22 T 31-10-2018 DFR85_08145 be2cf472723cad058e6246d362e2ccd8 822 Pfam PF03176 MMPL family 294 448 3.7E-21 T 31-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 DFR85_08145 be2cf472723cad058e6246d362e2ccd8 822 Pfam PF03176 MMPL family 660 818 7.5E-29 T 31-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 DFR85_05625 ea883913135e5ef80ee7f9c90346ff0e 335 Gene3D G3DSA:3.30.1330.10 1 148 6.0E-23 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily DFR85_05625 ea883913135e5ef80ee7f9c90346ff0e 335 Gene3D G3DSA:3.90.650.10 150 324 3.5E-36 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily DFR85_05625 ea883913135e5ef80ee7f9c90346ff0e 335 Pfam PF00586 AIR synthase related protein, N-terminal domain 48 140 8.0E-12 T 31-10-2018 IPR016188 PurM-like, N-terminal domain DFR85_05625 ea883913135e5ef80ee7f9c90346ff0e 335 Pfam PF02769 AIR synthase related protein, C-terminal domain 158 309 1.6E-21 T 31-10-2018 IPR010918 PurM-like, C-terminal domain DFR85_05625 ea883913135e5ef80ee7f9c90346ff0e 335 SUPERFAMILY SSF56042 155 326 1.3E-28 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily DFR85_05625 ea883913135e5ef80ee7f9c90346ff0e 335 PIRSF PIRSF005644 1 328 2.4E-100 T 31-10-2018 IPR011854 Carbamoyl dehydratase HypE DFR85_05625 ea883913135e5ef80ee7f9c90346ff0e 335 SUPERFAMILY SSF55326 16 144 2.09E-23 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily DFR85_10055 986714764d97810991b7be373320fd01 471 SUPERFAMILY SSF54368 5 100 1.44E-27 T 31-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DFR85_10055 986714764d97810991b7be373320fd01 471 Gene3D G3DSA:3.30.590.10 107 459 1.1E-125 T 31-10-2018 DFR85_10055 986714764d97810991b7be373320fd01 471 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 255 270 - T 31-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 DFR85_10055 986714764d97810991b7be373320fd01 471 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 6 470 4.5E-176 T 31-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DFR85_10055 986714764d97810991b7be373320fd01 471 SMART SM01230 104 381 7.6E-125 T 31-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DFR85_10055 986714764d97810991b7be373320fd01 471 Gene3D G3DSA:3.10.20.70 4 106 5.4E-30 T 31-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DFR85_10055 986714764d97810991b7be373320fd01 471 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 17 96 1.4E-25 T 31-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 DFR85_10055 986714764d97810991b7be373320fd01 471 SUPERFAMILY SSF55931 104 470 1.37E-116 T 31-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 DFR85_10055 986714764d97810991b7be373320fd01 471 Pfam PF00120 Glutamine synthetase, catalytic domain 104 468 2.4E-130 T 31-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DFR85_10055 986714764d97810991b7be373320fd01 471 ProSitePatterns PS00180 Glutamine synthetase signature 1. 53 71 - T 31-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 DFR85_03485 cb44d91d09ada0279786e7a6ea2c9e6f 349 SUPERFAMILY SSF81345 9 336 2.22E-65 T 31-10-2018 IPR037294 ABC transporter, BtuC-like DFR85_03485 cb44d91d09ada0279786e7a6ea2c9e6f 349 Gene3D G3DSA:1.10.3470.10 9 342 7.5E-79 T 31-10-2018 IPR037294 ABC transporter, BtuC-like DFR85_03485 cb44d91d09ada0279786e7a6ea2c9e6f 349 Pfam PF01032 FecCD transport family 21 337 1.4E-76 T 31-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 DFR85_02280 03970e98992ec8c203fd8a2b2d7f36de 776 Gene3D G3DSA:3.10.105.10 113 340 2.7E-26 T 31-10-2018 DFR85_02280 03970e98992ec8c203fd8a2b2d7f36de 776 Gene3D G3DSA:3.40.190.10 380 650 4.3E-19 T 31-10-2018 DFR85_02280 03970e98992ec8c203fd8a2b2d7f36de 776 SUPERFAMILY SSF53850 49 363 7.14E-31 T 31-10-2018 DFR85_02280 03970e98992ec8c203fd8a2b2d7f36de 776 Gene3D G3DSA:3.40.190.10 53 346 2.7E-26 T 31-10-2018 DFR85_02280 03970e98992ec8c203fd8a2b2d7f36de 776 SUPERFAMILY SSF53850 390 641 1.01E-13 T 31-10-2018 DFR85_02280 03970e98992ec8c203fd8a2b2d7f36de 776 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 52 292 7.8E-14 T 31-10-2018 IPR000914 Solute-binding protein family 5 domain DFR85_02280 03970e98992ec8c203fd8a2b2d7f36de 776 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 434 645 4.3E-12 T 31-10-2018 IPR000914 Solute-binding protein family 5 domain DFR85_15735 368f57b2507a429c3dfdd5c2087708ab 153 Pfam PF09941 Uncharacterized conserved protein (DUF2173) 31 85 2.2E-5 T 31-10-2018 IPR018685 Protein of unknown function DUF2173 DFR85_01860 3a12c80d65a34dbf4395a1d15c334c3d 357 Gene3D G3DSA:3.50.50.100 1 355 1.7E-70 T 31-10-2018 DFR85_01860 3a12c80d65a34dbf4395a1d15c334c3d 357 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 257 272 2.3E-6 T 31-10-2018 DFR85_01860 3a12c80d65a34dbf4395a1d15c334c3d 357 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 2.3E-6 T 31-10-2018 DFR85_01860 3a12c80d65a34dbf4395a1d15c334c3d 357 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 267 4.2E-28 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR85_01860 3a12c80d65a34dbf4395a1d15c334c3d 357 SUPERFAMILY SSF51905 3 288 8.91E-27 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_07750 377b9dca1ebe894d6f41e7168e2608eb 392 Gene3D G3DSA:1.10.150.390 338 383 1.1E-21 T 31-10-2018 DFR85_07750 377b9dca1ebe894d6f41e7168e2608eb 392 TIGRFAM TIGR02389 RNA_pol_rpoA2: DNA-directed RNA polymerase, subunit A'' 21 388 1.1E-156 T 31-10-2018 IPR012757 DNA-directed RNA polymerase subunit A'' GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR85_07750 377b9dca1ebe894d6f41e7168e2608eb 392 Hamap MF_00411 DNA-directed RNA polymerase subunit A'' [rpoA2]. 2 390 40.982 T 31-10-2018 IPR012757 DNA-directed RNA polymerase subunit A'' GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR85_07750 377b9dca1ebe894d6f41e7168e2608eb 392 Pfam PF04998 RNA polymerase Rpb1, domain 5 54 338 2.1E-57 T 31-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR85_07750 377b9dca1ebe894d6f41e7168e2608eb 392 SUPERFAMILY SSF64484 15 388 3.66E-103 T 31-10-2018 DFR85_11730 7fd2c6c7948acdb71e98eee66efe29ad 156 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 4 155 33.53 T 31-10-2018 IPR033747 Class I PurE DFR85_11730 7fd2c6c7948acdb71e98eee66efe29ad 156 SMART SM01001 2 151 2.6E-103 T 31-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 DFR85_11730 7fd2c6c7948acdb71e98eee66efe29ad 156 Gene3D G3DSA:3.40.50.7700 1 156 1.2E-73 T 31-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 DFR85_11730 7fd2c6c7948acdb71e98eee66efe29ad 156 SUPERFAMILY SSF52255 2 153 4.06E-67 T 31-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 DFR85_11730 7fd2c6c7948acdb71e98eee66efe29ad 156 PIRSF PIRSF001338 1 155 7.0E-72 T 31-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 DFR85_11730 7fd2c6c7948acdb71e98eee66efe29ad 156 Pfam PF00731 AIR carboxylase 4 149 4.0E-68 T 31-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 DFR85_11730 7fd2c6c7948acdb71e98eee66efe29ad 156 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 4 153 4.5E-70 T 31-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 DFR85_13540 2042cf53d9da1bd95a4dcec864dd8f54 494 Pfam PF13520 Amino acid permease 26 460 2.3E-19 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_13540 2042cf53d9da1bd95a4dcec864dd8f54 494 PIRSF PIRSF006060 1 493 1.2E-21 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_13540 2042cf53d9da1bd95a4dcec864dd8f54 494 Gene3D G3DSA:1.20.1740.10 11 484 4.6E-7 T 31-10-2018 DFR85_03570 5aca1063e626367b7cac438cb057402c 163 SUPERFAMILY SSF56770 13 161 1.35E-22 T 31-10-2018 DFR85_03570 5aca1063e626367b7cac438cb057402c 163 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 23 157 8.9E-18 T 31-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_03570 5aca1063e626367b7cac438cb057402c 163 Gene3D G3DSA:3.40.50.700 6 163 4.0E-31 T 31-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily DFR85_03985 08727769e48abc784dfe7929ccc42b24 547 Gene3D G3DSA:3.50.7.10 213 364 1.2E-180 T 31-10-2018 IPR027409 GroEL-like apical domain superfamily DFR85_03985 08727769e48abc784dfe7929ccc42b24 547 Pfam PF00118 TCP-1/cpn60 chaperonin family 29 519 2.3E-164 T 31-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 DFR85_03985 08727769e48abc784dfe7929ccc42b24 547 ProSitePatterns PS00995 Chaperonins TCP-1 signature 3. 83 91 - T 31-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR85_03985 08727769e48abc784dfe7929ccc42b24 547 SUPERFAMILY SSF48592 11 519 4.58E-82 T 31-10-2018 IPR027413 GroEL-like equatorial domain superfamily DFR85_03985 08727769e48abc784dfe7929ccc42b24 547 Gene3D G3DSA:3.30.260.10 141 400 1.2E-180 T 31-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily DFR85_03985 08727769e48abc784dfe7929ccc42b24 547 ProSitePatterns PS00750 Chaperonins TCP-1 signature 1. 34 46 - T 31-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR85_03985 08727769e48abc784dfe7929ccc42b24 547 SUPERFAMILY SSF54849 142 399 1.3E-23 T 31-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily DFR85_03985 08727769e48abc784dfe7929ccc42b24 547 Gene3D G3DSA:1.10.560.10 22 516 1.2E-180 T 31-10-2018 IPR027413 GroEL-like equatorial domain superfamily DFR85_03985 08727769e48abc784dfe7929ccc42b24 547 SUPERFAMILY SSF52029 209 373 5.23E-51 T 31-10-2018 IPR027409 GroEL-like apical domain superfamily DFR85_03985 08727769e48abc784dfe7929ccc42b24 547 TIGRFAM TIGR02339 thermosome_arch: thermosome, various subunits, archaeal 4 518 1.1E-207 T 31-10-2018 IPR012714 Thermosome, archaeal GO:0005524|GO:0006457|GO:0051082 DFR85_03985 08727769e48abc784dfe7929ccc42b24 547 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 402 414 2.5E-31 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR85_03985 08727769e48abc784dfe7929ccc42b24 547 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 53 71 2.5E-31 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR85_03985 08727769e48abc784dfe7929ccc42b24 547 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 83 102 2.5E-31 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR85_03985 08727769e48abc784dfe7929ccc42b24 547 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 368 390 2.5E-31 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR85_03985 08727769e48abc784dfe7929ccc42b24 547 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 31 47 2.5E-31 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR85_03985 08727769e48abc784dfe7929ccc42b24 547 ProSitePatterns PS00751 Chaperonins TCP-1 signature 2. 55 71 - T 31-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR85_08085 19989ebbd8acebfacf70fbd5adae0b36 569 Gene3D G3DSA:1.10.30.30 349 419 5.4E-117 T 31-10-2018 DFR85_08085 19989ebbd8acebfacf70fbd5adae0b36 569 Gene3D G3DSA:3.40.50.800 457 569 1.8E-32 T 31-10-2018 IPR036621 Anticodon-binding domain superfamily DFR85_08085 19989ebbd8acebfacf70fbd5adae0b36 569 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 4 554 1.2E-173 T 31-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 DFR85_08085 19989ebbd8acebfacf70fbd5adae0b36 569 Gene3D G3DSA:1.20.1430.20 83 146 5.4E-117 T 31-10-2018 DFR85_08085 19989ebbd8acebfacf70fbd5adae0b36 569 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 160 439 1.6E-7 T 31-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR85_08085 19989ebbd8acebfacf70fbd5adae0b36 569 SUPERFAMILY SSF52954 452 557 1.18E-32 T 31-10-2018 DFR85_08085 19989ebbd8acebfacf70fbd5adae0b36 569 Gene3D G3DSA:3.30.930.10 10 450 5.4E-117 T 31-10-2018 DFR85_08085 19989ebbd8acebfacf70fbd5adae0b36 569 PRINTS PR01043 Glycyl-tRNA synthetase signature 209 219 5.1E-52 T 31-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 DFR85_08085 19989ebbd8acebfacf70fbd5adae0b36 569 PRINTS PR01043 Glycyl-tRNA synthetase signature 425 437 5.1E-52 T 31-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 DFR85_08085 19989ebbd8acebfacf70fbd5adae0b36 569 PRINTS PR01043 Glycyl-tRNA synthetase signature 192 209 5.1E-52 T 31-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 DFR85_08085 19989ebbd8acebfacf70fbd5adae0b36 569 PRINTS PR01043 Glycyl-tRNA synthetase signature 160 177 5.1E-52 T 31-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 DFR85_08085 19989ebbd8acebfacf70fbd5adae0b36 569 PRINTS PR01043 Glycyl-tRNA synthetase signature 23 37 5.1E-52 T 31-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 DFR85_08085 19989ebbd8acebfacf70fbd5adae0b36 569 PRINTS PR01043 Glycyl-tRNA synthetase signature 502 521 5.1E-52 T 31-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 DFR85_08085 19989ebbd8acebfacf70fbd5adae0b36 569 PRINTS PR01043 Glycyl-tRNA synthetase signature 141 153 5.1E-52 T 31-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 DFR85_08085 19989ebbd8acebfacf70fbd5adae0b36 569 SUPERFAMILY SSF55681 5 468 2.11E-110 T 31-10-2018 DFR85_08085 19989ebbd8acebfacf70fbd5adae0b36 569 Pfam PF03129 Anticodon binding domain 466 553 1.7E-18 T 31-10-2018 IPR004154 Anticodon-binding DFR85_03010 e865add12e1a3523f967ab59adb308ee 206 Pfam PF00117 Glutamine amidotransferase class-I 29 166 4.2E-16 T 31-10-2018 IPR017926 Glutamine amidotransferase DFR85_03010 e865add12e1a3523f967ab59adb308ee 206 SUPERFAMILY SSF52317 31 205 2.01E-41 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like DFR85_03010 e865add12e1a3523f967ab59adb308ee 206 Gene3D G3DSA:3.40.50.880 1 206 1.7E-47 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like DFR85_03055 f1863e601325ab88882276c339836f2e 302 SMART SM00729 16 224 0.0065 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 DFR85_03055 f1863e601325ab88882276c339836f2e 302 SUPERFAMILY SSF102114 20 238 1.96E-29 T 31-10-2018 DFR85_03055 f1863e601325ab88882276c339836f2e 302 Pfam PF04055 Radical SAM superfamily 22 183 7.8E-20 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR85_03055 f1863e601325ab88882276c339836f2e 302 Pfam PF13394 4Fe-4S single cluster domain 26 118 6.3E-7 T 31-10-2018 DFR85_03055 f1863e601325ab88882276c339836f2e 302 Gene3D G3DSA:3.20.20.70 16 293 1.3E-25 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_07660 493e4b4dadc2006ab3a8fd8b4327059e 456 SMART SM00998 358 438 6.1E-22 T 31-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 DFR85_07660 493e4b4dadc2006ab3a8fd8b4327059e 456 Gene3D G3DSA:1.10.40.30 357 445 1.4E-17 T 31-10-2018 DFR85_07660 493e4b4dadc2006ab3a8fd8b4327059e 456 PRINTS PR00145 Argininosuccinate lyase family signature 270 286 1.7E-12 T 31-10-2018 DFR85_07660 493e4b4dadc2006ab3a8fd8b4327059e 456 PRINTS PR00145 Argininosuccinate lyase family signature 94 116 1.7E-12 T 31-10-2018 DFR85_07660 493e4b4dadc2006ab3a8fd8b4327059e 456 PRINTS PR00145 Argininosuccinate lyase family signature 226 250 1.7E-12 T 31-10-2018 DFR85_07660 493e4b4dadc2006ab3a8fd8b4327059e 456 PRINTS PR00145 Argininosuccinate lyase family signature 135 155 1.7E-12 T 31-10-2018 DFR85_07660 493e4b4dadc2006ab3a8fd8b4327059e 456 Pfam PF00206 Lyase 16 290 7.4E-48 T 31-10-2018 IPR022761 Fumarate lyase, N-terminal DFR85_07660 493e4b4dadc2006ab3a8fd8b4327059e 456 PRINTS PR00149 Fumarate lyase superfamily signature 270 286 1.2E-25 T 31-10-2018 IPR000362 Fumarate lyase family DFR85_07660 493e4b4dadc2006ab3a8fd8b4327059e 456 PRINTS PR00149 Fumarate lyase superfamily signature 226 253 1.2E-25 T 31-10-2018 IPR000362 Fumarate lyase family DFR85_07660 493e4b4dadc2006ab3a8fd8b4327059e 456 PRINTS PR00149 Fumarate lyase superfamily signature 95 113 1.2E-25 T 31-10-2018 IPR000362 Fumarate lyase family DFR85_07660 493e4b4dadc2006ab3a8fd8b4327059e 456 PRINTS PR00149 Fumarate lyase superfamily signature 140 158 1.2E-25 T 31-10-2018 IPR000362 Fumarate lyase family DFR85_07660 493e4b4dadc2006ab3a8fd8b4327059e 456 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 8 436 9.9E-136 T 31-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 DFR85_07660 493e4b4dadc2006ab3a8fd8b4327059e 456 SUPERFAMILY SSF48557 5 444 3.14E-121 T 31-10-2018 IPR008948 L-Aspartase-like GO:0003824 DFR85_07660 493e4b4dadc2006ab3a8fd8b4327059e 456 Pfam PF10397 Adenylosuccinate lyase C-terminus 359 436 1.3E-16 T 31-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 DFR85_07660 493e4b4dadc2006ab3a8fd8b4327059e 456 ProSitePatterns PS00163 Fumarate lyases signature. 270 279 - T 31-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 DFR85_07660 493e4b4dadc2006ab3a8fd8b4327059e 456 Gene3D G3DSA:1.20.200.10 100 355 8.9E-89 T 31-10-2018 DFR85_07660 493e4b4dadc2006ab3a8fd8b4327059e 456 Gene3D G3DSA:1.10.275.10 2 99 1.9E-27 T 31-10-2018 IPR024083 Fumarase/histidase, N-terminal DFR85_11650 126656ea7e3a289b9ecd8e200e5e304b 655 Pfam PF12895 Anaphase-promoting complex, cyclosome, subunit 3 244 316 1.0E-9 T 31-10-2018 DFR85_11650 126656ea7e3a289b9ecd8e200e5e304b 655 SUPERFAMILY SSF48452 233 325 2.01E-10 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 DFR85_11650 126656ea7e3a289b9ecd8e200e5e304b 655 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 365 386 - T 31-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 DFR85_11650 126656ea7e3a289b9ecd8e200e5e304b 655 Pfam PF00069 Protein kinase domain 359 625 9.0E-29 T 31-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DFR85_11650 126656ea7e3a289b9ecd8e200e5e304b 655 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 487 499 - T 31-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 DFR85_11650 126656ea7e3a289b9ecd8e200e5e304b 655 SMART SM00220 359 645 3.4E-19 T 31-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DFR85_11650 126656ea7e3a289b9ecd8e200e5e304b 655 SUPERFAMILY SSF56112 358 627 8.09E-41 T 31-10-2018 IPR011009 Protein kinase-like domain superfamily DFR85_11650 126656ea7e3a289b9ecd8e200e5e304b 655 Gene3D G3DSA:1.10.510.10 354 650 3.1E-37 T 31-10-2018 DFR85_08935 ad026a11d168ac12f69129adb6938f55 365 SMART SM01240 24 344 0.0018 T 31-10-2018 DFR85_08935 ad026a11d168ac12f69129adb6938f55 365 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 2 342 40.468 T 31-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 DFR85_08935 ad026a11d168ac12f69129adb6938f55 365 PIRSF PIRSF003314 1 352 7.1E-128 T 31-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 DFR85_08935 ad026a11d168ac12f69129adb6938f55 365 SUPERFAMILY SSF51395 25 359 5.13E-73 T 31-10-2018 DFR85_08935 ad026a11d168ac12f69129adb6938f55 365 Pfam PF01070 FMN-dependent dehydrogenase 26 338 1.9E-17 T 31-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 DFR85_08935 ad026a11d168ac12f69129adb6938f55 365 Gene3D G3DSA:3.20.20.70 1 365 5.1E-128 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_08935 ad026a11d168ac12f69129adb6938f55 365 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 4 340 1.8E-124 T 31-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 DFR85_12725 64e583c6f3f432b5a62325885ba7ea54 448 Pfam PF01547 Bacterial extracellular solute-binding protein 54 340 5.5E-20 T 31-10-2018 IPR006059 Bacterial extracellular solute-binding protein DFR85_12725 64e583c6f3f432b5a62325885ba7ea54 448 SUPERFAMILY SSF53850 43 410 1.36E-48 T 31-10-2018 DFR85_12725 64e583c6f3f432b5a62325885ba7ea54 448 Gene3D G3DSA:3.40.190.10 164 400 1.0E-43 T 31-10-2018 DFR85_12725 64e583c6f3f432b5a62325885ba7ea54 448 Gene3D G3DSA:3.40.190.10 64 385 1.0E-43 T 31-10-2018 DFR85_06860 b2acc196982cdb3fcd948a8584bec5e4 333 Gene3D G3DSA:3.50.50.60 125 247 2.5E-92 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_06860 b2acc196982cdb3fcd948a8584bec5e4 333 Gene3D G3DSA:3.50.50.60 12 306 2.5E-92 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_06860 b2acc196982cdb3fcd948a8584bec5e4 333 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 109 117 4.6E-47 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR85_06860 b2acc196982cdb3fcd948a8584bec5e4 333 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 63 73 4.6E-47 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR85_06860 b2acc196982cdb3fcd948a8584bec5e4 333 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 198 214 4.6E-47 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR85_06860 b2acc196982cdb3fcd948a8584bec5e4 333 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 146 170 4.6E-47 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR85_06860 b2acc196982cdb3fcd948a8584bec5e4 333 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 236 257 4.6E-47 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR85_06860 b2acc196982cdb3fcd948a8584bec5e4 333 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 43 58 4.6E-47 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR85_06860 b2acc196982cdb3fcd948a8584bec5e4 333 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 270 288 4.6E-47 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR85_06860 b2acc196982cdb3fcd948a8584bec5e4 333 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 11 33 4.6E-47 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR85_06860 b2acc196982cdb3fcd948a8584bec5e4 333 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 131 143 4.6E-47 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR85_06860 b2acc196982cdb3fcd948a8584bec5e4 333 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 282 1.1E-27 T 31-10-2018 DFR85_06860 b2acc196982cdb3fcd948a8584bec5e4 333 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 108 126 1.1E-27 T 31-10-2018 DFR85_06860 b2acc196982cdb3fcd948a8584bec5e4 333 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 150 168 1.1E-27 T 31-10-2018 DFR85_06860 b2acc196982cdb3fcd948a8584bec5e4 333 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 250 1.1E-27 T 31-10-2018 DFR85_06860 b2acc196982cdb3fcd948a8584bec5e4 333 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 1.1E-27 T 31-10-2018 DFR85_06860 b2acc196982cdb3fcd948a8584bec5e4 333 SUPERFAMILY SSF51905 9 308 4.6E-39 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_06860 b2acc196982cdb3fcd948a8584bec5e4 333 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 10 296 1.8E-38 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR85_06860 b2acc196982cdb3fcd948a8584bec5e4 333 SUPERFAMILY SSF51905 118 239 2.5E-18 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_15175 7dc21c1ec85c1daa8cfce1e3a09c7241 416 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 17 106 2.0E-8 T 31-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain DFR85_15175 7dc21c1ec85c1daa8cfce1e3a09c7241 416 SUPERFAMILY SSF54826 3 108 3.03E-19 T 31-10-2018 DFR85_15175 7dc21c1ec85c1daa8cfce1e3a09c7241 416 SMART SM00922 171 289 1.7E-19 T 31-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal DFR85_15175 7dc21c1ec85c1daa8cfce1e3a09c7241 416 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 235 266 - T 31-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 DFR85_15175 7dc21c1ec85c1daa8cfce1e3a09c7241 416 SUPERFAMILY SSF51604 94 412 2.15E-64 T 31-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily DFR85_15175 7dc21c1ec85c1daa8cfce1e3a09c7241 416 Pfam PF13378 Enolase C-terminal domain-like 175 406 3.5E-51 T 31-10-2018 IPR029065 Enolase C-terminal domain-like DFR85_12595 01bdb3923438d4b614b187677cd9b094 357 SUPERFAMILY SSF46785 286 356 1.48E-15 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_12595 01bdb3923438d4b614b187677cd9b094 357 Gene3D G3DSA:1.10.8.60 208 283 3.6E-26 T 31-10-2018 DFR85_12595 01bdb3923438d4b614b187677cd9b094 357 SUPERFAMILY SSF52540 3 280 2.24E-51 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_12595 01bdb3923438d4b614b187677cd9b094 357 Gene3D G3DSA:1.10.10.10 284 357 8.2E-29 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_12595 01bdb3923438d4b614b187677cd9b094 357 Pfam PF01637 ATPase domain predominantly from Archaea 14 247 2.4E-19 T 31-10-2018 IPR011579 ATPase domain GO:0005524 DFR85_12595 01bdb3923438d4b614b187677cd9b094 357 Gene3D G3DSA:3.40.50.300 1 207 5.6E-56 T 31-10-2018 DFR85_06575 76e8997766f8f9f9c47a078480ca27ef 262 Hamap MF_02082 [LysW]-aminoadipate/[LysW]-glutamate kinase [lysZ]. 1 262 48.116 T 31-10-2018 IPR037529 [LysW]-aminoadipate/[LysW]-glutamate kinase GO:0016301 DFR85_06575 76e8997766f8f9f9c47a078480ca27ef 262 PIRSF PIRSF000728 1 262 1.9E-67 T 31-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 DFR85_06575 76e8997766f8f9f9c47a078480ca27ef 262 TIGRFAM TIGR00761 argB: acetylglutamate kinase 1 241 2.2E-52 T 31-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 DFR85_06575 76e8997766f8f9f9c47a078480ca27ef 262 SUPERFAMILY SSF53633 1 261 6.41E-49 T 31-10-2018 IPR036393 Acetylglutamate kinase-like superfamily DFR85_06575 76e8997766f8f9f9c47a078480ca27ef 262 Pfam PF00696 Amino acid kinase family 1 242 2.0E-30 T 31-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 DFR85_06575 76e8997766f8f9f9c47a078480ca27ef 262 Gene3D G3DSA:3.40.1160.10 1 262 1.5E-53 T 31-10-2018 IPR036393 Acetylglutamate kinase-like superfamily DFR85_00845 e3b49f437aa7dd933ea1d098da60ecfe 140 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 5 137 2.4E-37 T 31-10-2018 IPR010419 Carbon monoxide dehydrogenase subunit G DFR85_00845 e3b49f437aa7dd933ea1d098da60ecfe 140 Gene3D G3DSA:3.30.530.20 1 140 2.4E-26 T 31-10-2018 IPR023393 START-like domain superfamily DFR85_00845 e3b49f437aa7dd933ea1d098da60ecfe 140 SUPERFAMILY SSF55961 1 138 1.92E-25 T 31-10-2018 DFR85_09180 dee791a5a05910db7f11033aee491b7f 144 Pfam PF03745 Domain of unknown function (DUF309) 62 113 2.1E-14 T 31-10-2018 IPR005500 Protein of unknown function DUF309 DFR85_09180 dee791a5a05910db7f11033aee491b7f 144 SUPERFAMILY SSF140663 58 133 7.72E-19 T 31-10-2018 IPR023203 TTHA0068-like superfamily DFR85_09180 dee791a5a05910db7f11033aee491b7f 144 Gene3D G3DSA:1.20.58.500 59 137 1.7E-13 T 31-10-2018 DFR85_07255 1fac3252bf5160cc0967e9414e7708c2 102 Gene3D G3DSA:2.30.30.70 2 96 4.7E-33 T 31-10-2018 IPR036948 Ribosomal protein L21 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07255 1fac3252bf5160cc0967e9414e7708c2 102 SUPERFAMILY SSF50104 4 95 2.05E-30 T 31-10-2018 IPR008991 Translation protein SH3-like domain superfamily DFR85_07255 1fac3252bf5160cc0967e9414e7708c2 102 ProSitePatterns PS01171 Ribosomal protein L21e signature. 39 64 - T 31-10-2018 IPR018259 Ribosomal protein L21e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07255 1fac3252bf5160cc0967e9414e7708c2 102 Pfam PF01157 Ribosomal protein L21e 4 94 3.0E-31 T 31-10-2018 IPR001147 Ribosomal protein L21e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07255 1fac3252bf5160cc0967e9414e7708c2 102 Hamap MF_00369 50S ribosomal protein L21e [rpl21e]. 3 98 26.757 T 31-10-2018 IPR022856 Ribosomal protein L21e, archaeal DFR85_15310 b9bf269835633c3bf3d6ac4c6e3e3fdf 426 Gene3D G3DSA:3.40.50.720 155 426 1.4E-86 T 31-10-2018 DFR85_15310 b9bf269835633c3bf3d6ac4c6e3e3fdf 426 Pfam PF03949 Malic enzyme, NAD binding domain 158 388 4.2E-26 T 31-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 DFR85_15310 b9bf269835633c3bf3d6ac4c6e3e3fdf 426 PRINTS PR00072 Malic enzyme signature 74 96 1.7E-11 T 31-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 DFR85_15310 b9bf269835633c3bf3d6ac4c6e3e3fdf 426 PRINTS PR00072 Malic enzyme signature 184 200 1.7E-11 T 31-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 DFR85_15310 b9bf269835633c3bf3d6ac4c6e3e3fdf 426 PRINTS PR00072 Malic enzyme signature 153 169 1.7E-11 T 31-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 DFR85_15310 b9bf269835633c3bf3d6ac4c6e3e3fdf 426 PRINTS PR00072 Malic enzyme signature 281 297 1.7E-11 T 31-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 DFR85_15310 b9bf269835633c3bf3d6ac4c6e3e3fdf 426 Pfam PF00390 Malic enzyme, N-terminal domain 13 144 2.0E-25 T 31-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 DFR85_15310 b9bf269835633c3bf3d6ac4c6e3e3fdf 426 SMART SM00919 157 389 4.1E-102 T 31-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 DFR85_15310 b9bf269835633c3bf3d6ac4c6e3e3fdf 426 SUPERFAMILY SSF53223 8 155 6.4E-54 T 31-10-2018 DFR85_15310 b9bf269835633c3bf3d6ac4c6e3e3fdf 426 SMART SM01274 12 145 1.4E-76 T 31-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 DFR85_15310 b9bf269835633c3bf3d6ac4c6e3e3fdf 426 Gene3D G3DSA:3.40.50.10380 2 154 4.6E-69 T 31-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 DFR85_15310 b9bf269835633c3bf3d6ac4c6e3e3fdf 426 PIRSF PIRSF000106 23 419 2.2E-80 T 31-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 DFR85_15310 b9bf269835633c3bf3d6ac4c6e3e3fdf 426 SUPERFAMILY SSF51735 157 417 1.47E-70 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_07520 b2b6daf1672e48620a41d2d578a594df 232 SUPERFAMILY SSF75445 130 206 4.32E-19 T 31-10-2018 DFR85_07520 b2b6daf1672e48620a41d2d578a594df 232 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 48 220 1.8E-43 T 31-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 DFR85_07520 b2b6daf1672e48620a41d2d578a594df 232 SUPERFAMILY SSF100950 2 147 1.26E-25 T 31-10-2018 IPR037171 NagB/RpiA transferase-like DFR85_07520 b2b6daf1672e48620a41d2d578a594df 232 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 5 221 3.1E-44 T 31-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 DFR85_07520 b2b6daf1672e48620a41d2d578a594df 232 Gene3D G3DSA:3.40.50.1360 5 220 3.8E-53 T 31-10-2018 DFR85_07520 b2b6daf1672e48620a41d2d578a594df 232 Gene3D G3DSA:3.30.70.260 127 203 3.8E-53 T 31-10-2018 DFR85_12135 f65de5d22d79785aa1960776e9ca1c50 284 PIRSF PIRSF009226 3 284 2.2E-93 T 31-10-2018 IPR009260 CRISPR-associated exonuclease Csa1 DFR85_12135 f65de5d22d79785aa1960776e9ca1c50 284 Gene3D G3DSA:3.90.320.10 159 284 5.8E-6 T 31-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal DFR85_12135 f65de5d22d79785aa1960776e9ca1c50 284 TIGRFAM TIGR01896 cas_AF1879: CRISPR-associated protein Cas4/Csa1, subtype I-A/APERN 11 283 3.1E-93 T 31-10-2018 IPR009260 CRISPR-associated exonuclease Csa1 DFR85_12135 f65de5d22d79785aa1960776e9ca1c50 284 Pfam PF06023 CRISPR-associated exonuclease Csa1 1 283 1.4E-87 T 31-10-2018 IPR009260 CRISPR-associated exonuclease Csa1 DFR85_05835 0167d70a6cea885aef6b425d4ce77fad 217 Pfam PF00149 Calcineurin-like phosphoesterase 3 187 4.0E-10 T 31-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 DFR85_05835 0167d70a6cea885aef6b425d4ce77fad 217 PIRSF PIRSF008292 1 217 1.1E-69 T 31-10-2018 IPR016538 Uncharacterised conserved protein UCP008292 DFR85_05835 0167d70a6cea885aef6b425d4ce77fad 217 SUPERFAMILY SSF56300 1 216 1.28E-20 T 31-10-2018 DFR85_05835 0167d70a6cea885aef6b425d4ce77fad 217 Gene3D G3DSA:3.60.21.10 1 214 1.4E-12 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like DFR85_06340 d259153fe256afda9330230395523e27 201 Pfam PF01930 Domain of unknown function DUF83 57 196 2.9E-8 T 31-10-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 DFR85_06340 d259153fe256afda9330230395523e27 201 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 23 197 3.4E-29 T 31-10-2018 IPR013343 CRISPR-associated protein Cas4 DFR85_06340 d259153fe256afda9330230395523e27 201 Gene3D G3DSA:3.90.320.10 1 201 7.6E-70 T 31-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal DFR85_06340 d259153fe256afda9330230395523e27 201 SUPERFAMILY SSF52980 106 158 5.27E-5 T 31-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 DFR85_01475 bc0705ce48d5d58df4fa39cebb5bae79 991 Gene3D G3DSA:3.30.465.40 16 225 5.7E-45 T 31-10-2018 DFR85_01475 bc0705ce48d5d58df4fa39cebb5bae79 991 Pfam PF01565 FAD binding domain 46 182 7.4E-35 T 31-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 DFR85_01475 bc0705ce48d5d58df4fa39cebb5bae79 991 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 516 527 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR85_01475 bc0705ce48d5d58df4fa39cebb5bae79 991 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 572 583 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR85_01475 bc0705ce48d5d58df4fa39cebb5bae79 991 SUPERFAMILY SSF56176 38 209 3.22E-46 T 31-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 DFR85_01475 bc0705ce48d5d58df4fa39cebb5bae79 991 Gene3D G3DSA:1.10.1060.10 500 602 2.7E-8 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 DFR85_01475 bc0705ce48d5d58df4fa39cebb5bae79 991 Pfam PF13534 4Fe-4S dicluster domain 516 586 1.1E-8 T 31-10-2018 DFR85_01475 bc0705ce48d5d58df4fa39cebb5bae79 991 SUPERFAMILY SSF55103 215 460 3.6E-7 T 31-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 DFR85_01475 bc0705ce48d5d58df4fa39cebb5bae79 991 SUPERFAMILY SSF46548 511 600 3.31E-14 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 DFR85_01735 a6d59b26dc264dd8ab49d30a1e0f8e40 647 PIRSF PIRSF006402 1 647 6.5E-162 T 31-10-2018 IPR024705 Spermatogenesis-associated protein 20 DFR85_01735 a6d59b26dc264dd8ab49d30a1e0f8e40 647 SUPERFAMILY SSF48208 185 490 1.36E-29 T 31-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 DFR85_01735 a6d59b26dc264dd8ab49d30a1e0f8e40 647 SUPERFAMILY SSF52833 7 125 1.8E-29 T 31-10-2018 IPR036249 Thioredoxin-like superfamily DFR85_01735 a6d59b26dc264dd8ab49d30a1e0f8e40 647 Pfam PF03190 Protein of unknown function, DUF255 2 160 1.9E-61 T 31-10-2018 IPR004879 Domain of unknown function DUF255 DFR85_01735 a6d59b26dc264dd8ab49d30a1e0f8e40 647 Gene3D G3DSA:3.40.30.10 1 166 2.1E-61 T 31-10-2018 DFR85_07860 cfbd84b5377b1b881b644d42202bc46d 370 Gene3D G3DSA:3.20.20.140 56 126 5.2E-6 T 31-10-2018 DFR85_07860 cfbd84b5377b1b881b644d42202bc46d 370 SUPERFAMILY SSF51556 57 318 1.15E-29 T 31-10-2018 IPR032466 Metal-dependent hydrolase DFR85_07860 cfbd84b5377b1b881b644d42202bc46d 370 Gene3D G3DSA:3.20.20.140 167 340 8.2E-19 T 31-10-2018 DFR85_07860 cfbd84b5377b1b881b644d42202bc46d 370 Gene3D G3DSA:2.30.40.10 18 55 5.2E-6 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR85_07860 cfbd84b5377b1b881b644d42202bc46d 370 Pfam PF01979 Amidohydrolase family 52 341 1.2E-13 T 31-10-2018 IPR006680 Amidohydrolase-related GO:0016787 DFR85_07860 cfbd84b5377b1b881b644d42202bc46d 370 SUPERFAMILY SSF51338 17 64 1.73E-7 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR85_08695 e42748234dcf6e2f33318de3b99d144c 264 SMART SM00852 6 173 5.1E-33 T 31-10-2018 IPR001453 MoaB/Mog domain DFR85_08695 e42748234dcf6e2f33318de3b99d144c 264 Pfam PF00994 Probable molybdopterin binding domain 6 172 8.1E-29 T 31-10-2018 IPR001453 MoaB/Mog domain DFR85_08695 e42748234dcf6e2f33318de3b99d144c 264 Gene3D G3DSA:3.40.980.10 4 174 1.2E-46 T 31-10-2018 IPR036425 MoaB/Mog-like domain superfamily DFR85_08695 e42748234dcf6e2f33318de3b99d144c 264 SUPERFAMILY SSF53218 3 205 8.38E-35 T 31-10-2018 IPR036425 MoaB/Mog-like domain superfamily DFR85_03105 cb8aae1c54b1e2c4f05099b500011d54 298 Pfam PF05726 Pirin C-terminal cupin domain 189 289 9.8E-29 T 31-10-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 DFR85_03105 cb8aae1c54b1e2c4f05099b500011d54 298 Gene3D G3DSA:2.60.120.10 16 285 2.4E-92 T 31-10-2018 IPR014710 RmlC-like jelly roll fold DFR85_03105 cb8aae1c54b1e2c4f05099b500011d54 298 SUPERFAMILY SSF51182 1 291 1.34E-82 T 31-10-2018 IPR011051 RmlC-like cupin domain superfamily DFR85_03105 cb8aae1c54b1e2c4f05099b500011d54 298 PIRSF PIRSF006232 1 296 1.2E-91 T 31-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 DFR85_03105 cb8aae1c54b1e2c4f05099b500011d54 298 Gene3D G3DSA:2.60.120.10 156 259 2.4E-92 T 31-10-2018 IPR014710 RmlC-like jelly roll fold DFR85_03105 cb8aae1c54b1e2c4f05099b500011d54 298 Pfam PF02678 Pirin 20 134 9.4E-37 T 31-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 DFR85_15545 cdb7987d0bea5a496d2d1c45a85ad18f 83 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 14 38 - T 31-10-2018 IPR001455 TusA-like domain DFR85_15545 cdb7987d0bea5a496d2d1c45a85ad18f 83 SUPERFAMILY SSF64307 7 81 3.79E-20 T 31-10-2018 IPR036868 TusA-like domain superfamily DFR85_15545 cdb7987d0bea5a496d2d1c45a85ad18f 83 Gene3D G3DSA:3.30.110.40 9 81 2.5E-22 T 31-10-2018 IPR036868 TusA-like domain superfamily DFR85_15545 cdb7987d0bea5a496d2d1c45a85ad18f 83 Pfam PF01206 Sulfurtransferase TusA 12 81 7.1E-20 T 31-10-2018 IPR001455 TusA-like domain DFR85_08135 464ac169a30174fb264fcc94cbfaa2f9 233 Pfam PF09376 NurA domain 120 199 1.9E-4 T 31-10-2018 IPR018977 NurA domain DFR85_08135 464ac169a30174fb264fcc94cbfaa2f9 233 SMART SM00933 19 200 4.2E-8 T 31-10-2018 IPR018977 NurA domain DFR85_07050 2eeb43aae2f357982fb4e83eea0714d3 128 Pfam PF00467 KOW motif 46 76 4.5E-6 T 31-10-2018 IPR005824 KOW DFR85_07050 2eeb43aae2f357982fb4e83eea0714d3 128 SMART SM00739 43 70 3.0E-4 T 31-10-2018 IPR005824 KOW DFR85_07050 2eeb43aae2f357982fb4e83eea0714d3 128 Pfam PF16906 Ribosomal proteins L26 eukaryotic, L24P archaeal 3 117 2.7E-25 T 31-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07050 2eeb43aae2f357982fb4e83eea0714d3 128 Gene3D G3DSA:2.30.30.30 1 128 1.3E-37 T 31-10-2018 IPR014722 Ribosomal protein L2, domain 2 DFR85_07050 2eeb43aae2f357982fb4e83eea0714d3 128 SUPERFAMILY SSF50104 3 111 2.49E-27 T 31-10-2018 IPR008991 Translation protein SH3-like domain superfamily DFR85_07050 2eeb43aae2f357982fb4e83eea0714d3 128 Hamap MF_01326_A 50S ribosomal protein L24 [rplX]. 3 116 25.932 T 31-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07050 2eeb43aae2f357982fb4e83eea0714d3 128 TIGRFAM TIGR01080 rplX_A_E: ribosomal protein uL24 4 117 2.3E-32 T 31-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_03790 b3388daf26df43f0c7bb7048eb45f103 107 SUPERFAMILY SSF50022 6 106 6.55E-27 T 31-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 DFR85_03790 b3388daf26df43f0c7bb7048eb45f103 107 PRINTS PR00162 Rieske 2Fe-2S subunit signature 79 91 2.6E-5 T 31-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 DFR85_03790 b3388daf26df43f0c7bb7048eb45f103 107 PRINTS PR00162 Rieske 2Fe-2S subunit signature 43 54 2.6E-5 T 31-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 DFR85_03790 b3388daf26df43f0c7bb7048eb45f103 107 PRINTS PR00162 Rieske 2Fe-2S subunit signature 66 78 2.6E-5 T 31-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 DFR85_03790 b3388daf26df43f0c7bb7048eb45f103 107 Pfam PF00355 Rieske [2Fe-2S] domain 7 94 5.6E-19 T 31-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DFR85_03790 b3388daf26df43f0c7bb7048eb45f103 107 Gene3D G3DSA:2.102.10.10 4 107 4.9E-29 T 31-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 DFR85_04395 eeee7a506915849ca479a08e1beb9b5b 278 SUPERFAMILY SSF53448 4 155 2.25E-21 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_04395 eeee7a506915849ca479a08e1beb9b5b 278 Gene3D G3DSA:3.90.550.10 2 178 1.7E-20 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_04395 eeee7a506915849ca479a08e1beb9b5b 278 Pfam PF00535 Glycosyl transferase family 2 5 109 2.9E-13 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 DFR85_00745 f97bd504bffab37e4322108b0f77f8f3 204 Gene3D G3DSA:3.60.15.10 1 201 1.6E-44 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR85_00745 f97bd504bffab37e4322108b0f77f8f3 204 Pfam PF13483 Beta-lactamase superfamily domain 2 159 4.9E-32 T 31-10-2018 DFR85_00745 f97bd504bffab37e4322108b0f77f8f3 204 SUPERFAMILY SSF56281 3 178 7.37E-24 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR85_03970 9bed80fa9325f56ef7e9d1d2c7b21209 285 Gene3D G3DSA:1.20.1250.20 1 283 5.0E-11 T 31-10-2018 DFR85_03970 9bed80fa9325f56ef7e9d1d2c7b21209 285 SUPERFAMILY SSF103473 7 283 1.2E-11 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_05775 b67a312af338c88c98cf49904a95ab54 223 Gene3D G3DSA:3.90.320.10 1 221 3.6E-45 T 31-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal DFR85_05775 b67a312af338c88c98cf49904a95ab54 223 Pfam PF01930 Domain of unknown function DUF83 31 217 1.4E-7 T 31-10-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 DFR85_14065 3fbf4ce0569b39db0b14010d78621f37 397 Gene3D G3DSA:1.10.540.10 5 129 3.5E-32 T 31-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 DFR85_14065 3fbf4ce0569b39db0b14010d78621f37 397 SUPERFAMILY SSF47203 237 393 1.21E-44 T 31-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 DFR85_14065 3fbf4ce0569b39db0b14010d78621f37 397 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 131 227 4.8E-23 T 31-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 DFR85_14065 3fbf4ce0569b39db0b14010d78621f37 397 Gene3D G3DSA:1.20.140.10 245 395 1.9E-42 T 31-10-2018 DFR85_14065 3fbf4ce0569b39db0b14010d78621f37 397 PIRSF PIRSF016578 10 392 2.9E-20 T 31-10-2018 DFR85_14065 3fbf4ce0569b39db0b14010d78621f37 397 SUPERFAMILY SSF56645 10 250 1.7E-75 T 31-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 DFR85_14065 3fbf4ce0569b39db0b14010d78621f37 397 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 241 389 2.0E-35 T 31-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DFR85_14065 3fbf4ce0569b39db0b14010d78621f37 397 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 17 127 5.0E-28 T 31-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 DFR85_14065 3fbf4ce0569b39db0b14010d78621f37 397 Gene3D G3DSA:2.40.110.10 130 244 8.4E-40 T 31-10-2018 DFR85_11295 907a4873c1adddb4f243835c439422b9 202 PIRSF PIRSF001435 1 202 1.1E-49 T 31-10-2018 DFR85_11295 907a4873c1adddb4f243835c439422b9 202 SMART SM00478 29 181 1.7E-13 T 31-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 DFR85_11295 907a4873c1adddb4f243835c439422b9 202 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 25 161 5.0E-9 T 31-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 DFR85_11295 907a4873c1adddb4f243835c439422b9 202 SUPERFAMILY SSF48150 8 201 6.44E-36 T 31-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 DFR85_11295 907a4873c1adddb4f243835c439422b9 202 Gene3D G3DSA:1.10.1670.10 123 202 6.4E-9 T 31-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 DFR85_11295 907a4873c1adddb4f243835c439422b9 202 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 183 199 - T 31-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 DFR85_11295 907a4873c1adddb4f243835c439422b9 202 Gene3D G3DSA:1.10.340.30 12 122 3.8E-23 T 31-10-2018 DFR85_08430 f59ee2304b39eaa9b145519a9770b9f8 130 SMART SM00529 25 122 5.1E-11 T 31-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 DFR85_08430 f59ee2304b39eaa9b145519a9770b9f8 130 SUPERFAMILY SSF46785 6 85 8.57E-9 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_08430 f59ee2304b39eaa9b145519a9770b9f8 130 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 9 57 1.3E-5 T 31-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 DFR85_08430 f59ee2304b39eaa9b145519a9770b9f8 130 SUPERFAMILY SSF47979 63 130 6.02E-18 T 31-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 DFR85_08430 f59ee2304b39eaa9b145519a9770b9f8 130 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 63 130 7.5E-20 T 31-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 DFR85_08430 f59ee2304b39eaa9b145519a9770b9f8 130 Gene3D G3DSA:1.10.10.10 1 130 8.2E-41 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_01630 f11152f65a989577dd85377d77632be2 241 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 70 103 - T 31-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 DFR85_01630 f11152f65a989577dd85377d77632be2 241 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 1 197 2.3E-40 T 31-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 DFR85_01630 f11152f65a989577dd85377d77632be2 241 Gene3D G3DSA:3.30.950.10 105 220 3.0E-28 T 31-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 DFR85_01630 f11152f65a989577dd85377d77632be2 241 Gene3D G3DSA:3.40.1010.10 1 104 2.1E-28 T 31-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 DFR85_01630 f11152f65a989577dd85377d77632be2 241 SUPERFAMILY SSF53790 1 237 7.72E-55 T 31-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 DFR85_02695 6e0912454c7abb3edd60e6696897343c 532 Gene3D G3DSA:1.20.1740.10 15 526 7.4E-12 T 31-10-2018 DFR85_02695 6e0912454c7abb3edd60e6696897343c 532 Pfam PF13520 Amino acid permease 35 499 1.6E-15 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_02695 6e0912454c7abb3edd60e6696897343c 532 PIRSF PIRSF006060 2 531 2.8E-26 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_05805 25fe430df2ef53d0532ebc50f301ecbe 258 Gene3D G3DSA:3.40.50.300 1 233 2.6E-68 T 31-10-2018 DFR85_05805 25fe430df2ef53d0532ebc50f301ecbe 258 SMART SM00382 21 196 0.004 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_05805 25fe430df2ef53d0532ebc50f301ecbe 258 TIGRFAM TIGR03881 KaiC_arch_4: KaiC domain protein, PAE1156 family 3 230 6.2E-115 T 31-10-2018 IPR022443 KaiC-related DFR85_05805 25fe430df2ef53d0532ebc50f301ecbe 258 SUPERFAMILY SSF52540 1 231 4.5E-40 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_05805 25fe430df2ef53d0532ebc50f301ecbe 258 PRINTS PR01874 DNA repair protein radA signature 55 72 4.4E-6 T 31-10-2018 DFR85_05805 25fe430df2ef53d0532ebc50f301ecbe 258 PRINTS PR01874 DNA repair protein radA signature 13 41 4.4E-6 T 31-10-2018 DFR85_05805 25fe430df2ef53d0532ebc50f301ecbe 258 Pfam PF06745 KaiC 5 229 1.0E-57 T 31-10-2018 IPR014774 KaiC-like domain DFR85_12455 9b2490eef1e4c07595cf585dcfb4a172 408 Pfam PF04143 Sulphur transport 44 398 9.7E-22 T 31-10-2018 IPR007272 Sulphur transport domain DFR85_02155 4fcd203c4b438e33d0c3ac8204af35e0 572 SUPERFAMILY SSF52540 308 569 1.31E-60 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_02155 4fcd203c4b438e33d0c3ac8204af35e0 572 Gene3D G3DSA:3.40.50.300 308 568 4.3E-76 T 31-10-2018 DFR85_02155 4fcd203c4b438e33d0c3ac8204af35e0 572 SUPERFAMILY SSF52540 47 293 2.09E-50 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_02155 4fcd203c4b438e33d0c3ac8204af35e0 572 Pfam PF09336 Vps4 C terminal oligomerisation domain 529 570 2.7E-7 T 31-10-2018 IPR015415 Vps4 oligomerisation, C-terminal DFR85_02155 4fcd203c4b438e33d0c3ac8204af35e0 572 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 350 476 6.7E-36 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 DFR85_02155 4fcd203c4b438e33d0c3ac8204af35e0 572 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 79 209 1.5E-39 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 DFR85_02155 4fcd203c4b438e33d0c3ac8204af35e0 572 Gene3D G3DSA:3.40.50.300 47 289 1.2E-58 T 31-10-2018 DFR85_02155 4fcd203c4b438e33d0c3ac8204af35e0 572 ProSitePatterns PS00674 AAA-protein family signature. 447 465 - T 31-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 DFR85_02155 4fcd203c4b438e33d0c3ac8204af35e0 572 SMART SM00382 346 479 6.4E-22 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_02155 4fcd203c4b438e33d0c3ac8204af35e0 572 SMART SM00382 75 212 7.7E-17 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_02155 4fcd203c4b438e33d0c3ac8204af35e0 572 ProSitePatterns PS00674 AAA-protein family signature. 180 198 - T 31-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 DFR85_02155 4fcd203c4b438e33d0c3ac8204af35e0 572 Gene3D G3DSA:1.10.8.60 478 553 4.3E-76 T 31-10-2018 DFR85_02155 4fcd203c4b438e33d0c3ac8204af35e0 572 Gene3D G3DSA:1.10.8.60 211 276 1.2E-58 T 31-10-2018 DFR85_03015 0359994c3921419d38c77bec5061330e 473 Gene3D G3DSA:1.20.1250.20 252 468 1.4E-17 T 31-10-2018 DFR85_03015 0359994c3921419d38c77bec5061330e 473 Gene3D G3DSA:1.20.1720.10 7 237 2.2E-44 T 31-10-2018 DFR85_03015 0359994c3921419d38c77bec5061330e 473 SUPERFAMILY SSF103473 6 463 1.44E-70 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_03015 0359994c3921419d38c77bec5061330e 473 Pfam PF07690 Major Facilitator Superfamily 15 404 1.1E-50 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_11325 2de9de5d7797fc2e6c5c618d30787d5f 325 SUPERFAMILY SSF54211 7 173 2.13E-38 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold DFR85_11325 2de9de5d7797fc2e6c5c618d30787d5f 325 TIGRFAM TIGR01240 mevDPdecarb: diphosphomevalonate decarboxylase 7 301 8.0E-81 T 31-10-2018 IPR029765 Diphosphomevalonate decarboxylase GO:0004163|GO:0005829|GO:0019287 KEGG: 00900+4.1.1.33|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168|Reactome: R-HSA-446199 DFR85_11325 2de9de5d7797fc2e6c5c618d30787d5f 325 Pfam PF00288 GHMP kinases N terminal domain 94 150 4.1E-7 T 31-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 DFR85_11325 2de9de5d7797fc2e6c5c618d30787d5f 325 Gene3D G3DSA:3.30.230.10 3 184 6.0E-62 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup DFR85_11325 2de9de5d7797fc2e6c5c618d30787d5f 325 PIRSF PIRSF015950 2 325 1.9E-104 T 31-10-2018 IPR005935 Diphosphomevalonate/phosphomevalonate decarboxylase GO:0008299|GO:0016831 Reactome: R-HSA-191273|Reactome: R-HSA-2426168|Reactome: R-HSA-446199 DFR85_11325 2de9de5d7797fc2e6c5c618d30787d5f 325 SUPERFAMILY SSF55060 179 322 3.45E-40 T 31-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily DFR85_11325 2de9de5d7797fc2e6c5c618d30787d5f 325 Gene3D G3DSA:3.30.70.890 185 325 1.2E-46 T 31-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily DFR85_05140 573d2b3f0a7f51dae606a08051601574 134 Gene3D G3DSA:3.40.50.1010 3 121 7.6E-10 T 31-10-2018 DFR85_05140 573d2b3f0a7f51dae606a08051601574 134 Pfam PF01850 PIN domain 4 111 6.2E-16 T 31-10-2018 IPR002716 PIN domain DFR85_05140 573d2b3f0a7f51dae606a08051601574 134 SUPERFAMILY SSF88723 1 125 3.08E-16 T 31-10-2018 IPR029060 PIN-like domain superfamily DFR85_05830 27dbf705fed2ac4136ebaa09cfe07f9a 215 Gene3D G3DSA:3.40.30.10 1 143 2.2E-42 T 31-10-2018 DFR85_05830 27dbf705fed2ac4136ebaa09cfe07f9a 215 Hamap MF_00401 Peroxiredoxin. 2 206 43.675 T 31-10-2018 IPR022915 Peroxiredoxin, TDXH subfamily GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 DFR85_05830 27dbf705fed2ac4136ebaa09cfe07f9a 215 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 158 191 8.3E-7 T 31-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 DFR85_05830 27dbf705fed2ac4136ebaa09cfe07f9a 215 Pfam PF00578 AhpC/TSA family 6 134 4.5E-31 T 31-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 DFR85_05830 27dbf705fed2ac4136ebaa09cfe07f9a 215 PIRSF PIRSF000239 1 209 8.5E-67 T 31-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 DFR85_05830 27dbf705fed2ac4136ebaa09cfe07f9a 215 SUPERFAMILY SSF52833 1 206 5.47E-60 T 31-10-2018 IPR036249 Thioredoxin-like superfamily DFR85_05830 27dbf705fed2ac4136ebaa09cfe07f9a 215 Gene3D G3DSA:3.30.1020.20 144 214 1.3E-12 T 31-10-2018 DFR85_14795 c288b0694d90acf2f14a594ad2bc7edb 367 PRINTS PR00359 B-class P450 signature 286 301 8.3E-42 T 31-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DFR85_14795 c288b0694d90acf2f14a594ad2bc7edb 367 PRINTS PR00359 B-class P450 signature 71 82 8.3E-42 T 31-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DFR85_14795 c288b0694d90acf2f14a594ad2bc7edb 367 PRINTS PR00359 B-class P450 signature 132 147 8.3E-42 T 31-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DFR85_14795 c288b0694d90acf2f14a594ad2bc7edb 367 PRINTS PR00359 B-class P450 signature 241 252 8.3E-42 T 31-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DFR85_14795 c288b0694d90acf2f14a594ad2bc7edb 367 PRINTS PR00359 B-class P450 signature 307 316 8.3E-42 T 31-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DFR85_14795 c288b0694d90acf2f14a594ad2bc7edb 367 PRINTS PR00359 B-class P450 signature 258 285 8.3E-42 T 31-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DFR85_14795 c288b0694d90acf2f14a594ad2bc7edb 367 PRINTS PR00359 B-class P450 signature 316 327 8.3E-42 T 31-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DFR85_14795 c288b0694d90acf2f14a594ad2bc7edb 367 PRINTS PR00359 B-class P450 signature 115 131 8.3E-42 T 31-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 DFR85_14795 c288b0694d90acf2f14a594ad2bc7edb 367 Gene3D G3DSA:1.10.630.10 1 366 3.5E-96 T 31-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 DFR85_14795 c288b0694d90acf2f14a594ad2bc7edb 367 Pfam PF00067 Cytochrome P450 242 351 4.3E-18 T 31-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 DFR85_14795 c288b0694d90acf2f14a594ad2bc7edb 367 SUPERFAMILY SSF48264 4 365 5.63E-73 T 31-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 DFR85_14795 c288b0694d90acf2f14a594ad2bc7edb 367 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 309 318 - T 31-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 DFR85_14795 c288b0694d90acf2f14a594ad2bc7edb 367 PRINTS PR00385 P450 superfamily signature 307 316 3.8E-6 T 31-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 DFR85_14795 c288b0694d90acf2f14a594ad2bc7edb 367 PRINTS PR00385 P450 superfamily signature 316 327 3.8E-6 T 31-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 DFR85_14795 c288b0694d90acf2f14a594ad2bc7edb 367 PRINTS PR00385 P450 superfamily signature 208 225 3.8E-6 T 31-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 DFR85_14795 c288b0694d90acf2f14a594ad2bc7edb 367 PRINTS PR00385 P450 superfamily signature 241 252 3.8E-6 T 31-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 DFR85_11585 5c790de1784866db241619ff8c1bdd78 510 PIRSF PIRSF006060 1 510 9.1E-33 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_11585 5c790de1784866db241619ff8c1bdd78 510 Gene3D G3DSA:1.20.1740.10 16 506 3.9E-13 T 31-10-2018 DFR85_11585 5c790de1784866db241619ff8c1bdd78 510 Pfam PF13520 Amino acid permease 36 476 1.2E-21 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_01505 935587660ff568134303da72fea7ca77 221 Gene3D G3DSA:3.30.70.1100 117 220 5.1E-22 T 31-10-2018 DFR85_01505 935587660ff568134303da72fea7ca77 221 Pfam PF06778 Chlorite dismutase 26 213 2.9E-42 T 31-10-2018 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase DFR85_01505 935587660ff568134303da72fea7ca77 221 SUPERFAMILY SSF54909 3 219 1.39E-53 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel DFR85_13040 d40ffd9581658c25d42838301a3df035 176 Pfam PF05942 Archaeal PaREP1/PaREP8 family 19 142 2.2E-22 T 31-10-2018 IPR010268 Archaeal PaREP1 DFR85_05915 6890a98b0d34d25304501c03b1cd9f0b 108 Pfam PF02635 DsrE/DsrF-like family 8 107 1.2E-13 T 31-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein DFR85_05915 6890a98b0d34d25304501c03b1cd9f0b 108 SUPERFAMILY SSF75169 1 107 4.71E-27 T 31-10-2018 IPR027396 DsrEFH-like DFR85_05915 6890a98b0d34d25304501c03b1cd9f0b 108 Gene3D G3DSA:3.40.1260.10 1 108 8.6E-34 T 31-10-2018 IPR027396 DsrEFH-like DFR85_07430 99f913902b6dad50e14252c08dc361ba 532 Gene3D G3DSA:3.40.50.300 198 333 6.2E-19 T 31-10-2018 DFR85_07430 99f913902b6dad50e14252c08dc361ba 532 Gene3D G3DSA:3.40.50.300 362 532 8.4E-32 T 31-10-2018 DFR85_07430 99f913902b6dad50e14252c08dc361ba 532 Pfam PF01935 Domain of unknown function DUF87 207 408 2.5E-29 T 31-10-2018 IPR002789 Helicase HerA, central domain DFR85_07430 99f913902b6dad50e14252c08dc361ba 532 SUPERFAMILY SSF52540 212 530 9.47E-40 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_08975 79104637c5a530130d994a44c1a05243 345 SUPERFAMILY SSF49503 47 166 3.69E-5 T 31-10-2018 IPR008972 Cupredoxin DFR85_13590 91b1449f14d3d8bcdf8d67ebc05f36cd 264 Pfam PF06157 Protein of unknown function (DUF973) 9 260 1.1E-39 T 31-10-2018 IPR009321 Protein of unknown function DUF973 DFR85_03420 88cf0ad6aabacc747d7b4376e5be7025 465 Pfam PF03916 Polysulphide reductase, NrfD 286 378 9.2E-11 T 31-10-2018 IPR005614 NrfD family DFR85_03420 88cf0ad6aabacc747d7b4376e5be7025 465 Pfam PF03916 Polysulphide reductase, NrfD 43 250 1.1E-35 T 31-10-2018 IPR005614 NrfD family DFR85_08395 dc21147563b0f0780f91276cb94319fe 324 SUPERFAMILY SSF52540 12 274 4.69E-55 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_08395 dc21147563b0f0780f91276cb94319fe 324 Gene3D G3DSA:3.40.50.300 52 259 3.5E-68 T 31-10-2018 DFR85_08395 dc21147563b0f0780f91276cb94319fe 324 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 21 317 2.1E-86 T 31-10-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 DFR85_08395 dc21147563b0f0780f91276cb94319fe 324 SMART SM00382 53 189 0.0036 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_08395 dc21147563b0f0780f91276cb94319fe 324 Pfam PF03308 ArgK protein 27 281 2.6E-81 T 31-10-2018 DFR85_06035 39a598b109ff151cfe4cec5568dca9b7 329 Gene3D G3DSA:3.50.50.60 2 327 3.7E-26 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_06035 39a598b109ff151cfe4cec5568dca9b7 329 SUPERFAMILY SSF51905 1 265 7.12E-16 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_14870 cbb0ba0eb5d3b3e6e67a57d68488357e 328 Gene3D G3DSA:3.30.70.20 2 71 1.1E-10 T 31-10-2018 DFR85_14870 cbb0ba0eb5d3b3e6e67a57d68488357e 328 SUPERFAMILY SSF46548 2 73 7.32E-20 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 DFR85_14870 cbb0ba0eb5d3b3e6e67a57d68488357e 328 Pfam PF02754 Cysteine-rich domain 233 315 1.0E-7 T 31-10-2018 IPR004017 Cysteine-rich domain DFR85_14870 cbb0ba0eb5d3b3e6e67a57d68488357e 328 Pfam PF02754 Cysteine-rich domain 131 206 2.5E-6 T 31-10-2018 IPR004017 Cysteine-rich domain DFR85_14870 cbb0ba0eb5d3b3e6e67a57d68488357e 328 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 48 59 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR85_14870 cbb0ba0eb5d3b3e6e67a57d68488357e 328 Pfam PF13183 4Fe-4S dicluster domain 3 62 2.2E-11 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR85_14870 cbb0ba0eb5d3b3e6e67a57d68488357e 328 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 6 17 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR85_08505 1c33674cac0f6d3e19cbb9eb61f44d1d 436 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 262 280 1.5E-15 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR85_08505 1c33674cac0f6d3e19cbb9eb61f44d1d 436 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 141 165 1.5E-15 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR85_08505 1c33674cac0f6d3e19cbb9eb61f44d1d 436 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 228 249 1.5E-15 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR85_08505 1c33674cac0f6d3e19cbb9eb61f44d1d 436 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 103 111 1.5E-15 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR85_08505 1c33674cac0f6d3e19cbb9eb61f44d1d 436 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 1.5E-15 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR85_08505 1c33674cac0f6d3e19cbb9eb61f44d1d 436 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 145 163 3.4E-27 T 31-10-2018 DFR85_08505 1c33674cac0f6d3e19cbb9eb61f44d1d 436 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 3.4E-27 T 31-10-2018 DFR85_08505 1c33674cac0f6d3e19cbb9eb61f44d1d 436 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 252 274 3.4E-27 T 31-10-2018 DFR85_08505 1c33674cac0f6d3e19cbb9eb61f44d1d 436 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 226 242 3.4E-27 T 31-10-2018 DFR85_08505 1c33674cac0f6d3e19cbb9eb61f44d1d 436 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 3.4E-27 T 31-10-2018 DFR85_08505 1c33674cac0f6d3e19cbb9eb61f44d1d 436 Gene3D G3DSA:3.50.50.60 111 430 1.6E-130 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_08505 1c33674cac0f6d3e19cbb9eb61f44d1d 436 Gene3D G3DSA:3.50.50.60 3 330 1.6E-130 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_08505 1c33674cac0f6d3e19cbb9eb61f44d1d 436 SUPERFAMILY SSF51905 3 306 8.25E-32 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_08505 1c33674cac0f6d3e19cbb9eb61f44d1d 436 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 297 5.1E-49 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR85_08505 1c33674cac0f6d3e19cbb9eb61f44d1d 436 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 320 423 2.1E-16 T 31-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 DFR85_08505 1c33674cac0f6d3e19cbb9eb61f44d1d 436 SUPERFAMILY SSF55424 313 434 7.9E-32 T 31-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 DFR85_06955 ace68f362c1f3c4ed46edbdcc9c40fa8 140 Pfam PF01951 Archease protein family (MTH1598/TM1083) 4 140 4.0E-43 T 31-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 DFR85_06955 ace68f362c1f3c4ed46edbdcc9c40fa8 140 ProDom PD012969 UPF0211 RIKEN CDNA ENRICHED MALE FULL-LENGTH LIBRARY ZBTB8OS ADULT C43H8.1 8 125 3.0E-44 T 31-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 DFR85_06955 ace68f362c1f3c4ed46edbdcc9c40fa8 140 Hamap MF_01222 Protein archease. 2 140 38.992 T 31-10-2018 IPR022952 Archease, archaea DFR85_06955 ace68f362c1f3c4ed46edbdcc9c40fa8 140 Gene3D G3DSA:3.55.10.10 1 140 2.9E-47 T 31-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 DFR85_06955 ace68f362c1f3c4ed46edbdcc9c40fa8 140 SUPERFAMILY SSF69819 2 140 2.09E-41 T 31-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 DFR85_02845 d0cf938f3dae6aa2e2c6dca31d90d100 382 SUPERFAMILY SSF53383 2 381 1.38E-93 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase DFR85_02845 d0cf938f3dae6aa2e2c6dca31d90d100 382 Pfam PF00155 Aminotransferase class I and II 55 377 1.3E-32 T 31-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 DFR85_02845 d0cf938f3dae6aa2e2c6dca31d90d100 382 Gene3D G3DSA:3.90.1150.10 22 381 1.0E-116 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 DFR85_02845 d0cf938f3dae6aa2e2c6dca31d90d100 382 Gene3D G3DSA:3.40.640.10 62 277 1.0E-116 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR85_11845 e5c3718847de5a47e72cf7c12100bec4 220 Pfam PF13743 Thioredoxin 6 183 1.4E-20 T 31-10-2018 DFR85_11845 e5c3718847de5a47e72cf7c12100bec4 220 Gene3D G3DSA:3.40.30.10 1 206 1.4E-33 T 31-10-2018 DFR85_11845 e5c3718847de5a47e72cf7c12100bec4 220 SUPERFAMILY SSF52833 2 205 2.6E-35 T 31-10-2018 IPR036249 Thioredoxin-like superfamily DFR85_12285 66671ff8a164b4f565a5980b20a1b312 366 SUPERFAMILY SSF102114 42 334 3.01E-45 T 31-10-2018 DFR85_12285 66671ff8a164b4f565a5980b20a1b312 366 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 44 55 - T 31-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 DFR85_12285 66671ff8a164b4f565a5980b20a1b312 366 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 263 343 1.8E-15 T 31-10-2018 IPR023885 4Fe4S-binding SPASM domain DFR85_12285 66671ff8a164b4f565a5980b20a1b312 366 Pfam PF13353 4Fe-4S single cluster domain 42 154 7.3E-10 T 31-10-2018 DFR85_12285 66671ff8a164b4f565a5980b20a1b312 366 Gene3D G3DSA:3.20.20.70 40 365 2.5E-57 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_12285 66671ff8a164b4f565a5980b20a1b312 366 Pfam PF04055 Radical SAM superfamily 46 195 2.3E-16 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR85_05740 fdf3269fe1c6ddd482dc3cac05d9a4c7 422 Gene3D G3DSA:1.20.1250.20 11 420 8.1E-89 T 31-10-2018 DFR85_05740 fdf3269fe1c6ddd482dc3cac05d9a4c7 422 PRINTS PR00171 Sugar transporter signature 345 357 3.5E-5 T 31-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 DFR85_05740 fdf3269fe1c6ddd482dc3cac05d9a4c7 422 PRINTS PR00171 Sugar transporter signature 23 33 3.5E-5 T 31-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 DFR85_05740 fdf3269fe1c6ddd482dc3cac05d9a4c7 422 PRINTS PR00171 Sugar transporter signature 106 125 3.5E-5 T 31-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 DFR85_05740 fdf3269fe1c6ddd482dc3cac05d9a4c7 422 SUPERFAMILY SSF103473 9 416 1.24E-70 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_05740 fdf3269fe1c6ddd482dc3cac05d9a4c7 422 Pfam PF00083 Sugar (and other) transporter 16 416 6.7E-46 T 31-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 DFR85_06775 2e1ae77915100757c8001669340a3c2f 233 Pfam PF13192 Thioredoxin domain 39 118 3.5E-10 T 31-10-2018 IPR012336 Thioredoxin-like fold DFR85_06775 2e1ae77915100757c8001669340a3c2f 233 Pfam PF13192 Thioredoxin domain 146 224 2.1E-15 T 31-10-2018 IPR012336 Thioredoxin-like fold DFR85_06775 2e1ae77915100757c8001669340a3c2f 233 TIGRFAM TIGR02187 GlrX_arch: glutaredoxin-like domain protein 11 228 1.1E-75 T 31-10-2018 IPR011903 Glutaredoxin-like domain DFR85_06775 2e1ae77915100757c8001669340a3c2f 233 Gene3D G3DSA:3.40.30.10 9 125 8.2E-26 T 31-10-2018 DFR85_06775 2e1ae77915100757c8001669340a3c2f 233 Gene3D G3DSA:3.40.30.10 132 228 1.3E-23 T 31-10-2018 DFR85_06775 2e1ae77915100757c8001669340a3c2f 233 SUPERFAMILY SSF52833 10 127 9.59E-15 T 31-10-2018 IPR036249 Thioredoxin-like superfamily DFR85_06775 2e1ae77915100757c8001669340a3c2f 233 SUPERFAMILY SSF52833 134 226 8.51E-15 T 31-10-2018 IPR036249 Thioredoxin-like superfamily DFR85_01150 9583cfab4a5d8535156c230eb10044c9 388 SUPERFAMILY SSF48179 296 387 1.02E-21 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 DFR85_01150 9583cfab4a5d8535156c230eb10044c9 388 Gene3D G3DSA:1.10.1040.10 185 293 1.0E-23 T 31-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 DFR85_01150 9583cfab4a5d8535156c230eb10044c9 388 Gene3D G3DSA:3.40.50.720 1 184 1.0E-63 T 31-10-2018 DFR85_01150 9583cfab4a5d8535156c230eb10044c9 388 SUPERFAMILY SSF51735 2 178 1.12E-52 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_01150 9583cfab4a5d8535156c230eb10044c9 388 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2 178 4.1E-63 T 31-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 DFR85_01150 9583cfab4a5d8535156c230eb10044c9 388 Gene3D G3DSA:1.10.1040.10 300 388 2.7E-22 T 31-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 DFR85_01150 9583cfab4a5d8535156c230eb10044c9 388 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 296 387 3.4E-19 T 31-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 DFR85_01150 9583cfab4a5d8535156c230eb10044c9 388 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 183 277 2.7E-24 T 31-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 DFR85_01150 9583cfab4a5d8535156c230eb10044c9 388 SUPERFAMILY SSF48179 182 288 4.17E-21 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 DFR85_14160 d8a2bf894d88a7ff9943baca4d82960b 350 PIRSF PIRSF005644 3 350 2.5E-108 T 31-10-2018 IPR011854 Carbamoyl dehydratase HypE DFR85_14160 d8a2bf894d88a7ff9943baca4d82960b 350 Pfam PF02769 AIR synthase related protein, C-terminal domain 178 327 8.2E-23 T 31-10-2018 IPR010918 PurM-like, C-terminal domain DFR85_14160 d8a2bf894d88a7ff9943baca4d82960b 350 Gene3D G3DSA:3.30.1330.10 11 155 1.6E-42 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily DFR85_14160 d8a2bf894d88a7ff9943baca4d82960b 350 SUPERFAMILY SSF56042 176 344 1.47E-35 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily DFR85_14160 d8a2bf894d88a7ff9943baca4d82960b 350 SUPERFAMILY SSF55326 9 152 1.36E-27 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily DFR85_14160 d8a2bf894d88a7ff9943baca4d82960b 350 Pfam PF00586 AIR synthase related protein, N-terminal domain 44 149 9.1E-16 T 31-10-2018 IPR016188 PurM-like, N-terminal domain DFR85_14160 d8a2bf894d88a7ff9943baca4d82960b 350 TIGRFAM TIGR02124 hypE: hydrogenase expression/formation protein HypE 8 350 5.3E-111 T 31-10-2018 IPR011854 Carbamoyl dehydratase HypE DFR85_14160 d8a2bf894d88a7ff9943baca4d82960b 350 Gene3D G3DSA:3.90.650.10 175 350 5.2E-48 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily DFR85_09825 c465e015f45abf787e290d9450b0682b 312 Pfam PF02779 Transketolase, pyrimidine binding domain 8 166 2.1E-38 T 31-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain DFR85_09825 c465e015f45abf787e290d9450b0682b 312 SUPERFAMILY SSF52922 177 311 9.16E-34 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 DFR85_09825 c465e015f45abf787e290d9450b0682b 312 Gene3D G3DSA:3.40.50.970 5 178 3.3E-57 T 31-10-2018 DFR85_09825 c465e015f45abf787e290d9450b0682b 312 SMART SM00861 7 172 2.2E-50 T 31-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain DFR85_09825 c465e015f45abf787e290d9450b0682b 312 SUPERFAMILY SSF52518 8 172 3.27E-51 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR85_09825 c465e015f45abf787e290d9450b0682b 312 Pfam PF02780 Transketolase, C-terminal domain 183 303 7.6E-29 T 31-10-2018 IPR033248 Transketolase, C-terminal domain DFR85_09825 c465e015f45abf787e290d9450b0682b 312 Gene3D G3DSA:3.40.50.920 183 312 5.3E-38 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 DFR85_12030 faec52015e67d8cf30bcd46f092fd69d 378 Pfam PF02589 LUD domain 51 281 4.1E-52 T 31-10-2018 IPR003741 LUD domain DFR85_12030 faec52015e67d8cf30bcd46f092fd69d 378 SUPERFAMILY SSF46548 293 373 2.27E-14 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 DFR85_12030 faec52015e67d8cf30bcd46f092fd69d 378 Pfam PF13183 4Fe-4S dicluster domain 298 361 5.8E-10 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR85_12030 faec52015e67d8cf30bcd46f092fd69d 378 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 300 311 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR85_12030 faec52015e67d8cf30bcd46f092fd69d 378 SUPERFAMILY SSF100950 46 282 6.28E-45 T 31-10-2018 IPR037171 NagB/RpiA transferase-like DFR85_12030 faec52015e67d8cf30bcd46f092fd69d 378 Gene3D G3DSA:1.10.1060.10 282 377 2.3E-5 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 DFR85_12030 faec52015e67d8cf30bcd46f092fd69d 378 Gene3D G3DSA:3.40.50.10420 126 281 7.4E-28 T 31-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily DFR85_02760 c48a33b1d2f12b48254663911e9709c8 435 SUPERFAMILY SSF51556 71 367 1.08E-51 T 31-10-2018 IPR032466 Metal-dependent hydrolase DFR85_02760 c48a33b1d2f12b48254663911e9709c8 435 Pfam PF01979 Amidohydrolase family 68 417 4.7E-23 T 31-10-2018 IPR006680 Amidohydrolase-related GO:0016787 DFR85_02760 c48a33b1d2f12b48254663911e9709c8 435 SUPERFAMILY SSF51338 20 434 6.61E-27 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR85_02760 c48a33b1d2f12b48254663911e9709c8 435 Gene3D G3DSA:3.20.20.140 71 365 1.1E-96 T 31-10-2018 DFR85_02760 c48a33b1d2f12b48254663911e9709c8 435 Gene3D G3DSA:2.30.40.10 22 431 1.1E-96 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR85_08700 ec35c477c4e5c7a045d58b910093cdb3 252 Pfam PF12146 Serine aminopeptidase, S33 22 217 4.5E-18 T 31-10-2018 IPR022742 Serine aminopeptidase, S33 DFR85_08700 ec35c477c4e5c7a045d58b910093cdb3 252 SUPERFAMILY SSF53474 6 252 6.26E-52 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold DFR85_08700 ec35c477c4e5c7a045d58b910093cdb3 252 PRINTS PR00111 Alpha/beta hydrolase fold signature 89 102 5.9E-8 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 DFR85_08700 ec35c477c4e5c7a045d58b910093cdb3 252 PRINTS PR00111 Alpha/beta hydrolase fold signature 201 215 5.9E-8 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 DFR85_08700 ec35c477c4e5c7a045d58b910093cdb3 252 PRINTS PR00111 Alpha/beta hydrolase fold signature 45 60 5.9E-8 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 DFR85_08700 ec35c477c4e5c7a045d58b910093cdb3 252 Gene3D G3DSA:3.40.50.1820 6 252 6.0E-52 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold DFR85_12060 68b88d61d303756228f3750b14293262 737 SUPERFAMILY SSF50998 615 720 4.55E-11 T 31-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily DFR85_12060 68b88d61d303756228f3750b14293262 737 SMART SM00564 671 702 290.0 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DFR85_12060 68b88d61d303756228f3750b14293262 737 SMART SM00564 470 502 0.0057 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DFR85_12060 68b88d61d303756228f3750b14293262 737 SMART SM00564 365 397 4.6E-6 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DFR85_12060 68b88d61d303756228f3750b14293262 737 SMART SM00564 628 661 9.5 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DFR85_12060 68b88d61d303756228f3750b14293262 737 SUPERFAMILY SSF50998 301 616 1.13E-20 T 31-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily DFR85_12060 68b88d61d303756228f3750b14293262 737 Pfam PF06053 Domain of unknown function (DUF929) 10 260 1.2E-52 T 31-10-2018 IPR009272 Protein of unknown function DUF929 DFR85_12060 68b88d61d303756228f3750b14293262 737 Gene3D G3DSA:2.130.10.10 338 731 4.0E-38 T 31-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 DFR85_12060 68b88d61d303756228f3750b14293262 737 Pfam PF13360 PQQ-like domain 340 506 1.4E-13 T 31-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat DFR85_06130 945a161b192f5a91134647da50d23033 374 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 5 371 1.3E-126 T 31-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 DFR85_06130 945a161b192f5a91134647da50d23033 374 PIRSF PIRSF001434 2 374 7.3E-133 T 31-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 DFR85_06130 945a161b192f5a91134647da50d23033 374 Gene3D G3DSA:3.40.640.10 4 238 4.1E-69 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR85_06130 945a161b192f5a91134647da50d23033 374 SUPERFAMILY SSF53383 33 372 1.61E-96 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase DFR85_06130 945a161b192f5a91134647da50d23033 374 Gene3D G3DSA:3.90.1150.10 239 374 1.6E-51 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 DFR85_11665 6a56b8ed14256b56a5e3bd6438ec2351 125 SUPERFAMILY SSF55298 3 125 5.65E-44 T 31-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 DFR85_11665 6a56b8ed14256b56a5e3bd6438ec2351 125 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 101 119 - T 31-10-2018 IPR019897 RidA, conserved site Reactome: R-HSA-8849175 DFR85_11665 6a56b8ed14256b56a5e3bd6438ec2351 125 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 3 124 3.8E-50 T 31-10-2018 IPR006056 RidA family Reactome: R-HSA-8849175 DFR85_11665 6a56b8ed14256b56a5e3bd6438ec2351 125 Pfam PF01042 Endoribonuclease L-PSP 8 125 1.2E-42 T 31-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 DFR85_11665 6a56b8ed14256b56a5e3bd6438ec2351 125 Gene3D G3DSA:3.30.1330.40 1 124 5.2E-53 T 31-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 DFR85_10190 26f8c5390a6e50c9fe03defa29d81213 903 SUPERFAMILY SSF55681 60 254 2.65E-56 T 31-10-2018 DFR85_10190 26f8c5390a6e50c9fe03defa29d81213 903 SUPERFAMILY SSF101353 304 506 7.32E-41 T 31-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 DFR85_10190 26f8c5390a6e50c9fe03defa29d81213 903 Pfam PF01411 tRNA synthetases class II (A) 63 592 8.5E-120 T 31-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 DFR85_10190 26f8c5390a6e50c9fe03defa29d81213 903 Gene3D G3DSA:3.30.54.20 660 715 2.5E-46 T 31-10-2018 DFR85_10190 26f8c5390a6e50c9fe03defa29d81213 903 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 64 876 1.1E-196 T 31-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 DFR85_10190 26f8c5390a6e50c9fe03defa29d81213 903 PRINTS PR00980 Alanyl-tRNA synthetase signature 129 140 6.2E-16 T 31-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 DFR85_10190 26f8c5390a6e50c9fe03defa29d81213 903 PRINTS PR00980 Alanyl-tRNA synthetase signature 350 363 6.2E-16 T 31-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 DFR85_10190 26f8c5390a6e50c9fe03defa29d81213 903 PRINTS PR00980 Alanyl-tRNA synthetase signature 235 248 6.2E-16 T 31-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 DFR85_10190 26f8c5390a6e50c9fe03defa29d81213 903 PRINTS PR00980 Alanyl-tRNA synthetase signature 326 342 6.2E-16 T 31-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 DFR85_10190 26f8c5390a6e50c9fe03defa29d81213 903 PRINTS PR00980 Alanyl-tRNA synthetase signature 209 220 6.2E-16 T 31-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 DFR85_10190 26f8c5390a6e50c9fe03defa29d81213 903 Pfam PF02272 DHHA1 domain 775 875 7.6E-6 T 31-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 DFR85_10190 26f8c5390a6e50c9fe03defa29d81213 903 Gene3D G3DSA:3.30.980.10 592 733 2.5E-46 T 31-10-2018 DFR85_10190 26f8c5390a6e50c9fe03defa29d81213 903 Gene3D G3DSA:3.30.930.10 1 250 1.4E-96 T 31-10-2018 DFR85_10190 26f8c5390a6e50c9fe03defa29d81213 903 Gene3D G3DSA:2.40.30.130 491 588 3.5E-28 T 31-10-2018 DFR85_10190 26f8c5390a6e50c9fe03defa29d81213 903 TIGRFAM TIGR03683 A-tRNA_syn_arch: alanine--tRNA ligase 5 897 0.0 T 31-10-2018 IPR022429 Alanine-tRNA ligase, archaea GO:0000166|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 DFR85_10190 26f8c5390a6e50c9fe03defa29d81213 903 Hamap MF_00036_A Alanine--tRNA ligase [alaS]. 7 896 22.35 T 31-10-2018 IPR022429 Alanine-tRNA ligase, archaea GO:0000166|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 DFR85_10190 26f8c5390a6e50c9fe03defa29d81213 903 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 691 734 3.6E-14 T 31-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 DFR85_10190 26f8c5390a6e50c9fe03defa29d81213 903 SMART SM00863 691 734 2.1E-17 T 31-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 DFR85_10190 26f8c5390a6e50c9fe03defa29d81213 903 SUPERFAMILY SSF55186 592 738 3.01E-44 T 31-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 DFR85_10190 26f8c5390a6e50c9fe03defa29d81213 903 SUPERFAMILY SSF50447 500 588 1.62E-18 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily DFR85_08810 a399f5c3f59e4ada9b693829d40cb10c 494 Gene3D G3DSA:2.40.50.140 2 141 1.0E-34 T 31-10-2018 DFR85_08810 a399f5c3f59e4ada9b693829d40cb10c 494 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 6 489 37.536 T 31-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 DFR85_08810 a399f5c3f59e4ada9b693829d40cb10c 494 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 5 487 1.6E-160 T 31-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 DFR85_08810 a399f5c3f59e4ada9b693829d40cb10c 494 Pfam PF01336 OB-fold nucleic acid binding domain 55 131 1.3E-10 T 31-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 DFR85_08810 a399f5c3f59e4ada9b693829d40cb10c 494 PRINTS PR00982 Lysyl-tRNA synthetase signature 182 192 7.5E-33 T 31-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 DFR85_08810 a399f5c3f59e4ada9b693829d40cb10c 494 PRINTS PR00982 Lysyl-tRNA synthetase signature 245 262 7.5E-33 T 31-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 DFR85_08810 a399f5c3f59e4ada9b693829d40cb10c 494 PRINTS PR00982 Lysyl-tRNA synthetase signature 198 214 7.5E-33 T 31-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 DFR85_08810 a399f5c3f59e4ada9b693829d40cb10c 494 PRINTS PR00982 Lysyl-tRNA synthetase signature 227 240 7.5E-33 T 31-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 DFR85_08810 a399f5c3f59e4ada9b693829d40cb10c 494 PRINTS PR00982 Lysyl-tRNA synthetase signature 371 387 7.5E-33 T 31-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 DFR85_08810 a399f5c3f59e4ada9b693829d40cb10c 494 SUPERFAMILY SSF55681 145 485 3.38E-104 T 31-10-2018 DFR85_08810 a399f5c3f59e4ada9b693829d40cb10c 494 SUPERFAMILY SSF50249 5 140 1.25E-31 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR85_08810 a399f5c3f59e4ada9b693829d40cb10c 494 Pfam PF00152 tRNA synthetases class II (D, K and N) 146 485 4.5E-81 T 31-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR85_08810 a399f5c3f59e4ada9b693829d40cb10c 494 Gene3D G3DSA:3.30.930.10 159 487 1.2E-117 T 31-10-2018 DFR85_11570 d1788295e4e6d547fc15446a2c369417 395 Gene3D G3DSA:1.20.1250.20 203 394 2.6E-16 T 31-10-2018 DFR85_11570 d1788295e4e6d547fc15446a2c369417 395 Pfam PF07690 Major Facilitator Superfamily 14 234 2.1E-17 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_11570 d1788295e4e6d547fc15446a2c369417 395 Gene3D G3DSA:1.20.1250.20 4 193 3.0E-17 T 31-10-2018 DFR85_11570 d1788295e4e6d547fc15446a2c369417 395 SUPERFAMILY SSF103473 1 393 4.58E-44 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_14760 ff464f5bbe799dbaed0aab4b1098bfeb 547 Pfam PF13193 AMP-binding enzyme C-terminal domain 454 527 7.2E-15 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain DFR85_14760 ff464f5bbe799dbaed0aab4b1098bfeb 547 Gene3D G3DSA:3.30.300.310 440 543 1.7E-25 T 31-10-2018 DFR85_14760 ff464f5bbe799dbaed0aab4b1098bfeb 547 SUPERFAMILY SSF56801 25 540 6.15E-136 T 31-10-2018 DFR85_14760 ff464f5bbe799dbaed0aab4b1098bfeb 547 Gene3D G3DSA:3.40.50.12780 15 439 1.3E-109 T 31-10-2018 DFR85_14760 ff464f5bbe799dbaed0aab4b1098bfeb 547 Pfam PF00501 AMP-binding enzyme 32 444 4.2E-97 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 DFR85_04940 85a65346665138538f7c9d9ce83ec67c 303 Gene3D G3DSA:3.90.550.10 4 206 9.5E-19 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_04940 85a65346665138538f7c9d9ce83ec67c 303 SUPERFAMILY SSF53448 6 268 2.81E-26 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_04940 85a65346665138538f7c9d9ce83ec67c 303 Pfam PF00535 Glycosyl transferase family 2 9 132 9.6E-11 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 DFR85_00225 208b411426f8ea15d83d67252593a358 216 Pfam PF06525 Sulfocyanin (SoxE) domain 70 214 8.2E-59 T 31-10-2018 IPR010532 Sulfocyanin GO:0005507|GO:0055114 DFR85_00225 208b411426f8ea15d83d67252593a358 216 ProSitePatterns PS00079 Multicopper oxidases signature 1. 182 202 - T 31-10-2018 IPR033138 Multicopper oxidases, conserved site DFR85_00225 208b411426f8ea15d83d67252593a358 216 PIRSF PIRSF022145 2 216 1.9E-71 T 31-10-2018 IPR010532 Sulfocyanin GO:0005507|GO:0055114 DFR85_00225 208b411426f8ea15d83d67252593a358 216 Gene3D G3DSA:2.60.40.420 44 203 9.1E-22 T 31-10-2018 IPR008972 Cupredoxin DFR85_00225 208b411426f8ea15d83d67252593a358 216 SUPERFAMILY SSF49503 66 203 4.14E-18 T 31-10-2018 IPR008972 Cupredoxin DFR85_00225 208b411426f8ea15d83d67252593a358 216 TIGRFAM TIGR03094 sulfo_cyanin: sulfocyanin 57 215 8.4E-53 T 31-10-2018 IPR010532 Sulfocyanin GO:0005507|GO:0055114 DFR85_12810 7c85810f93e163a815dde1be396fd22f 353 Pfam PF02371 Transposase IS116/IS110/IS902 family 232 317 1.3E-23 T 31-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 DFR85_00940 ac6abe7af696c9cdafb872188fa4cd9c 145 Gene3D G3DSA:3.90.79.10 2 139 3.7E-30 T 31-10-2018 DFR85_00940 ac6abe7af696c9cdafb872188fa4cd9c 145 Pfam PF00293 NUDIX domain 5 112 3.1E-21 T 31-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 DFR85_00940 ac6abe7af696c9cdafb872188fa4cd9c 145 SUPERFAMILY SSF55811 5 136 1.49E-30 T 31-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 DFR85_09815 477819bc79eea3c8f61eb8809f493aec 331 Gene3D G3DSA:3.20.20.70 53 323 1.8E-99 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_09815 477819bc79eea3c8f61eb8809f493aec 331 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 65 322 5.6E-126 T 31-10-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 DFR85_09815 477819bc79eea3c8f61eb8809f493aec 331 SUPERFAMILY SSF51569 51 329 7.05E-95 T 31-10-2018 DFR85_09815 477819bc79eea3c8f61eb8809f493aec 331 Pfam PF00793 DAHP synthetase I family 82 316 2.7E-70 T 31-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 DFR85_12765 a2d53b3af70b2d2d92b66d4c291d3fb0 430 Pfam PF13173 AAA domain 39 164 3.3E-20 T 31-10-2018 DFR85_12765 a2d53b3af70b2d2d92b66d4c291d3fb0 430 SUPERFAMILY SSF52540 4 189 3.06E-15 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_12765 a2d53b3af70b2d2d92b66d4c291d3fb0 430 Gene3D G3DSA:3.40.50.300 16 122 4.6E-7 T 31-10-2018 DFR85_12765 a2d53b3af70b2d2d92b66d4c291d3fb0 430 SMART SM00382 35 161 0.0029 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_12765 a2d53b3af70b2d2d92b66d4c291d3fb0 430 Pfam PF13635 Domain of unknown function (DUF4143) 254 381 4.7E-7 T 31-10-2018 IPR025420 Domain of unknown function DUF4143 DFR85_12930 477ef811ae431a6d7447647a4ed525b9 382 Pfam PF07690 Major Facilitator Superfamily 23 337 2.1E-12 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_12930 477ef811ae431a6d7447647a4ed525b9 382 Gene3D G3DSA:1.20.1250.20 10 371 2.2E-16 T 31-10-2018 DFR85_12930 477ef811ae431a6d7447647a4ed525b9 382 SUPERFAMILY SSF103473 16 371 1.44E-17 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_09800 e5f4dbcc12082adb174802e964c120a8 390 TIGRFAM TIGR00033 aroC: chorismate synthase 10 356 1.1E-122 T 31-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 DFR85_09800 e5f4dbcc12082adb174802e964c120a8 390 ProSitePatterns PS00787 Chorismate synthase signature 1. 16 31 - T 31-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 DFR85_09800 e5f4dbcc12082adb174802e964c120a8 390 ProSitePatterns PS00789 Chorismate synthase signature 3. 328 344 - T 31-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 DFR85_09800 e5f4dbcc12082adb174802e964c120a8 390 PIRSF PIRSF001456 3 373 1.9E-141 T 31-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 DFR85_09800 e5f4dbcc12082adb174802e964c120a8 390 Gene3D G3DSA:3.60.150.10 1 367 4.1E-134 T 31-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 DFR85_09800 e5f4dbcc12082adb174802e964c120a8 390 Pfam PF01264 Chorismate synthase 10 353 2.5E-125 T 31-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 DFR85_09800 e5f4dbcc12082adb174802e964c120a8 390 Hamap MF_00300 Chorismate synthase [aroC]. 10 361 36.135 T 31-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 DFR85_09800 e5f4dbcc12082adb174802e964c120a8 390 SUPERFAMILY SSF103263 4 357 3.27E-126 T 31-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 DFR85_11255 78e8f6ab44202f1c85b6fe93e5ab1ad6 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 117 125 1.6E-9 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_11255 78e8f6ab44202f1c85b6fe93e5ab1ad6 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 156 1.6E-9 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_11255 78e8f6ab44202f1c85b6fe93e5ab1ad6 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 64 75 1.6E-9 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_11255 78e8f6ab44202f1c85b6fe93e5ab1ad6 244 SUPERFAMILY SSF51735 2 227 7.77E-54 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_11255 78e8f6ab44202f1c85b6fe93e5ab1ad6 244 Gene3D G3DSA:3.40.50.720 1 241 5.3E-54 T 31-10-2018 DFR85_11255 78e8f6ab44202f1c85b6fe93e5ab1ad6 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 111 127 6.2E-25 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_11255 78e8f6ab44202f1c85b6fe93e5ab1ad6 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 156 6.2E-25 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_11255 78e8f6ab44202f1c85b6fe93e5ab1ad6 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 6.2E-25 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_11255 78e8f6ab44202f1c85b6fe93e5ab1ad6 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 64 75 6.2E-25 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_11255 78e8f6ab44202f1c85b6fe93e5ab1ad6 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 175 6.2E-25 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_11255 78e8f6ab44202f1c85b6fe93e5ab1ad6 244 Pfam PF00106 short chain dehydrogenase 2 175 2.0E-43 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_04500 f868bd00d9ff7ecf880afc8155ef1879 185 Gene3D G3DSA:3.60.21.10 5 185 1.0E-18 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like DFR85_04500 f868bd00d9ff7ecf880afc8155ef1879 185 SUPERFAMILY SSF56300 12 167 9.08E-18 T 31-10-2018 DFR85_04500 f868bd00d9ff7ecf880afc8155ef1879 185 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 12 162 9.0E-11 T 31-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 DFR85_01980 577654b5c7403bc2624681a44605cc84 406 Gene3D G3DSA:1.20.1250.20 1 400 9.4E-29 T 31-10-2018 DFR85_01980 577654b5c7403bc2624681a44605cc84 406 Pfam PF07690 Major Facilitator Superfamily 10 369 1.0E-19 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_01980 577654b5c7403bc2624681a44605cc84 406 SUPERFAMILY SSF103473 2 402 1.15E-35 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_09890 049e0a328042c8f0939805c8db5f8c4f 646 Gene3D G3DSA:2.160.20.60 367 571 8.1E-24 T 31-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 DFR85_09890 049e0a328042c8f0939805c8db5f8c4f 646 Pfam PF01493 GXGXG motif 375 531 3.3E-23 T 31-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 DFR85_09890 049e0a328042c8f0939805c8db5f8c4f 646 SUPERFAMILY SSF69336 357 560 5.89E-42 T 31-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 DFR85_09890 049e0a328042c8f0939805c8db5f8c4f 646 PIRSF PIRSF036632 1 646 0.0 T 31-10-2018 IPR012075 Glutamate synthase, large subunit domains 1/3 fusion DFR85_09890 049e0a328042c8f0939805c8db5f8c4f 646 SUPERFAMILY SSF56235 7 343 1.63E-51 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR85_02045 645bd178a64c8f13917267c497a12765 294 PIRSF PIRSF001365 1 289 9.6E-56 T 31-10-2018 IPR002220 DapA-like GO:0016829 DFR85_02045 645bd178a64c8f13917267c497a12765 294 Pfam PF00701 Dihydrodipicolinate synthetase family 2 278 6.0E-40 T 31-10-2018 IPR002220 DapA-like GO:0016829 DFR85_02045 645bd178a64c8f13917267c497a12765 294 Gene3D G3DSA:3.20.20.70 2 287 1.9E-82 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_02045 645bd178a64c8f13917267c497a12765 294 SMART SM01130 1 280 3.6E-47 T 31-10-2018 IPR002220 DapA-like GO:0016829 DFR85_02045 645bd178a64c8f13917267c497a12765 294 PRINTS PR00146 Dihydrodipicolinate synthase signature 124 141 1.7E-9 T 31-10-2018 IPR002220 DapA-like GO:0016829 DFR85_02045 645bd178a64c8f13917267c497a12765 294 PRINTS PR00146 Dihydrodipicolinate synthase signature 66 84 1.7E-9 T 31-10-2018 IPR002220 DapA-like GO:0016829 DFR85_02045 645bd178a64c8f13917267c497a12765 294 PRINTS PR00146 Dihydrodipicolinate synthase signature 33 54 1.7E-9 T 31-10-2018 IPR002220 DapA-like GO:0016829 DFR85_02045 645bd178a64c8f13917267c497a12765 294 SUPERFAMILY SSF51569 3 280 4.4E-59 T 31-10-2018 DFR85_01880 69a835a1b7044d04eaa1e8768a2ffbda 307 Gene3D G3DSA:1.20.1260.10 3 136 8.8E-6 T 31-10-2018 IPR012347 Ferritin-like DFR85_01880 69a835a1b7044d04eaa1e8768a2ffbda 307 Pfam PF01988 VIT family 142 217 1.9E-14 T 31-10-2018 IPR008217 Ccc1 family DFR85_01880 69a835a1b7044d04eaa1e8768a2ffbda 307 Pfam PF01988 VIT family 216 300 6.3E-14 T 31-10-2018 IPR008217 Ccc1 family DFR85_01880 69a835a1b7044d04eaa1e8768a2ffbda 307 Pfam PF02915 Rubrerythrin 5 132 2.1E-6 T 31-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 DFR85_01880 69a835a1b7044d04eaa1e8768a2ffbda 307 SUPERFAMILY SSF47240 4 133 1.2E-9 T 31-10-2018 IPR009078 Ferritin-like superfamily DFR85_04465 6bc43c19eb4fff679444f3e2887f3432 85 Gene3D G3DSA:3.40.1260.10 1 85 6.9E-13 T 31-10-2018 IPR027396 DsrEFH-like DFR85_04465 6bc43c19eb4fff679444f3e2887f3432 85 Pfam PF02635 DsrE/DsrF-like family 39 84 4.3E-7 T 31-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein DFR85_04465 6bc43c19eb4fff679444f3e2887f3432 85 SUPERFAMILY SSF75169 34 84 5.89E-13 T 31-10-2018 IPR027396 DsrEFH-like DFR85_13835 dd4c35e3b3f9ad5f0017432749bc4bbd 384 Pfam PF00108 Thiolase, N-terminal domain 20 221 3.0E-11 T 31-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 DFR85_13835 dd4c35e3b3f9ad5f0017432749bc4bbd 384 PIRSF PIRSF000429 1 382 4.2E-29 T 31-10-2018 IPR002155 Thiolase GO:0016747 DFR85_13835 dd4c35e3b3f9ad5f0017432749bc4bbd 384 SUPERFAMILY SSF53901 228 383 7.49E-17 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR85_13835 dd4c35e3b3f9ad5f0017432749bc4bbd 384 SUPERFAMILY SSF53901 4 226 1.79E-32 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR85_13835 dd4c35e3b3f9ad5f0017432749bc4bbd 384 Gene3D G3DSA:3.40.47.10 1 384 4.3E-89 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR85_06915 c83adb16896c383bc859f54d45e80335 417 SUPERFAMILY SSF52507 22 219 2.22E-45 T 31-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 DFR85_06915 c83adb16896c383bc859f54d45e80335 417 Gene3D G3DSA:3.40.50.1950 17 195 3.6E-46 T 31-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 DFR85_06915 c83adb16896c383bc859f54d45e80335 417 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 195 381 9.5E-52 T 31-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 DFR85_06915 c83adb16896c383bc859f54d45e80335 417 Pfam PF02441 Flavoprotein 24 171 5.2E-38 T 31-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 DFR85_06915 c83adb16896c383bc859f54d45e80335 417 SUPERFAMILY SSF102645 193 411 1.7E-56 T 31-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 DFR85_06915 c83adb16896c383bc859f54d45e80335 417 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 20 405 1.4E-101 T 31-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 DFR85_06915 c83adb16896c383bc859f54d45e80335 417 Gene3D G3DSA:3.40.50.10300 196 414 7.0E-59 T 31-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 DFR85_10545 61291085a4a62781966aa99d5391905f 806 SUPERFAMILY SSF50677 194 340 1.22E-47 T 31-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 DFR85_10545 61291085a4a62781966aa99d5391905f 806 TIGRFAM TIGR00422 valS: valine--tRNA ligase 5 796 1.1E-215 T 31-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 DFR85_10545 61291085a4a62781966aa99d5391905f 806 Pfam PF08264 Anticodon-binding domain of tRNA 612 750 3.8E-28 T 31-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 DFR85_10545 61291085a4a62781966aa99d5391905f 806 SUPERFAMILY SSF52374 2 579 1.15E-112 T 31-10-2018 DFR85_10545 61291085a4a62781966aa99d5391905f 806 Gene3D G3DSA:3.40.50.620 24 535 4.9E-214 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR85_10545 61291085a4a62781966aa99d5391905f 806 Gene3D G3DSA:1.10.730.10 5 741 4.9E-214 T 31-10-2018 DFR85_10545 61291085a4a62781966aa99d5391905f 806 Gene3D G3DSA:3.90.740.10 177 342 4.9E-214 T 31-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 DFR85_10545 61291085a4a62781966aa99d5391905f 806 PRINTS PR00986 Valyl-tRNA synthetase signature 486 504 3.2E-13 T 31-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 DFR85_10545 61291085a4a62781966aa99d5391905f 806 PRINTS PR00986 Valyl-tRNA synthetase signature 42 53 3.2E-13 T 31-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 DFR85_10545 61291085a4a62781966aa99d5391905f 806 PRINTS PR00986 Valyl-tRNA synthetase signature 231 248 3.2E-13 T 31-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 DFR85_10545 61291085a4a62781966aa99d5391905f 806 PRINTS PR00986 Valyl-tRNA synthetase signature 455 476 3.2E-13 T 31-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 DFR85_10545 61291085a4a62781966aa99d5391905f 806 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 49 60 - T 31-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR85_10545 61291085a4a62781966aa99d5391905f 806 SUPERFAMILY SSF47323 586 792 1.76E-47 T 31-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR85_10545 61291085a4a62781966aa99d5391905f 806 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 17 570 2.1E-122 T 31-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR85_01325 854cea45104bf4e48b9f16747c839940 235 SUPERFAMILY SSF142535 4 232 4.45E-64 T 31-10-2018 DFR85_01325 854cea45104bf4e48b9f16747c839940 235 Gene3D G3DSA:3.40.50.10700 153 233 4.1E-14 T 31-10-2018 DFR85_01325 854cea45104bf4e48b9f16747c839940 235 PIRSF PIRSF016210 1 235 8.0E-63 T 31-10-2018 IPR018033 D-aminoacyl-tRNA deacylase, archaea GO:0016788|GO:0019478|GO:0051499 DFR85_01325 854cea45104bf4e48b9f16747c839940 235 Gene3D G3DSA:3.40.630.50 2 148 3.8E-37 T 31-10-2018 DFR85_01325 854cea45104bf4e48b9f16747c839940 235 Pfam PF04414 D-aminoacyl-tRNA deacylase 35 232 9.1E-57 T 31-10-2018 IPR007508 D-aminoacyl-tRNA deacylase DtdA GO:0016788|GO:0051499 DFR85_01325 854cea45104bf4e48b9f16747c839940 235 Hamap MF_00562 D-aminoacyl-tRNA deacylase [dtdA]. 2 234 29.786 T 31-10-2018 IPR018033 D-aminoacyl-tRNA deacylase, archaea GO:0016788|GO:0019478|GO:0051499 DFR85_14770 9e7938ca2eff0de07559bc60eba294f4 372 Gene3D G3DSA:1.20.1250.20 191 363 3.3E-19 T 31-10-2018 DFR85_14770 9e7938ca2eff0de07559bc60eba294f4 372 SUPERFAMILY SSF103473 2 360 5.62E-37 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_14770 9e7938ca2eff0de07559bc60eba294f4 372 Gene3D G3DSA:1.20.1250.20 2 181 8.4E-14 T 31-10-2018 DFR85_14770 9e7938ca2eff0de07559bc60eba294f4 372 Pfam PF07690 Major Facilitator Superfamily 199 358 2.8E-15 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_14770 9e7938ca2eff0de07559bc60eba294f4 372 Pfam PF07690 Major Facilitator Superfamily 10 167 1.7E-12 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_01485 ce783512c24c6b4cd26c31a0ebc62ae8 201 Pfam PF00857 Isochorismatase family 22 190 2.1E-36 T 31-10-2018 IPR000868 Isochorismatase-like GO:0003824 DFR85_01485 ce783512c24c6b4cd26c31a0ebc62ae8 201 Gene3D G3DSA:3.40.50.850 2 193 1.0E-40 T 31-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 DFR85_01485 ce783512c24c6b4cd26c31a0ebc62ae8 201 SUPERFAMILY SSF52499 10 196 3.79E-42 T 31-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 DFR85_05455 e0127305de4fdc0d21d78b55952142ca 330 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 266 1.6E-38 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR85_05455 e0127305de4fdc0d21d78b55952142ca 330 Gene3D G3DSA:3.50.50.100 1 329 3.0E-63 T 31-10-2018 DFR85_05455 e0127305de4fdc0d21d78b55952142ca 330 SUPERFAMILY SSF51905 98 276 8.1E-25 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_05455 e0127305de4fdc0d21d78b55952142ca 330 SUPERFAMILY SSF51971 2 150 6.83E-8 T 31-10-2018 DFR85_05455 e0127305de4fdc0d21d78b55952142ca 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 226 248 3.9E-8 T 31-10-2018 DFR85_05455 e0127305de4fdc0d21d78b55952142ca 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 122 140 3.9E-8 T 31-10-2018 DFR85_05455 e0127305de4fdc0d21d78b55952142ca 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 3.9E-8 T 31-10-2018 DFR85_11820 d5a4c984f04df7de17d2cbf6ae6a143e 364 Gene3D G3DSA:3.30.930.10 21 251 5.9E-46 T 31-10-2018 DFR85_11820 d5a4c984f04df7de17d2cbf6ae6a143e 364 Gene3D G3DSA:3.30.390.50 263 353 4.3E-16 T 31-10-2018 DFR85_11820 d5a4c984f04df7de17d2cbf6ae6a143e 364 SUPERFAMILY SSF55681 1 247 9.23E-52 T 31-10-2018 DFR85_07415 4813b7461b4ace0a4d26ba5bcf866d69 125 Gene3D G3DSA:3.40.1350.10 31 123 5.4E-16 T 31-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 DFR85_07415 4813b7461b4ace0a4d26ba5bcf866d69 125 SUPERFAMILY SSF53032 34 122 1.45E-13 T 31-10-2018 IPR036167 tRNA intron endonuclease, catalytic domain-like superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 DFR85_07415 4813b7461b4ace0a4d26ba5bcf866d69 125 Pfam PF01974 tRNA intron endonuclease, catalytic C-terminal domain 34 114 4.2E-9 T 31-10-2018 IPR006677 tRNA intron endonuclease, catalytic domain-like GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 DFR85_12850 8f14ced9c5fc6f3023d52ca5ae41c18b 537 SUPERFAMILY SSF52540 125 520 1.82E-30 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_12850 8f14ced9c5fc6f3023d52ca5ae41c18b 537 Pfam PF01935 Domain of unknown function DUF87 155 354 2.0E-15 T 31-10-2018 IPR002789 Helicase HerA, central domain DFR85_12850 8f14ced9c5fc6f3023d52ca5ae41c18b 537 SMART SM00382 178 495 2.0E-4 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_12850 8f14ced9c5fc6f3023d52ca5ae41c18b 537 Gene3D G3DSA:3.40.50.300 144 266 1.4E-10 T 31-10-2018 DFR85_12850 8f14ced9c5fc6f3023d52ca5ae41c18b 537 Gene3D G3DSA:3.40.50.300 339 531 1.8E-19 T 31-10-2018 DFR85_14660 538f149d85e6e19a6cbb62860d9fc6bb 241 SUPERFAMILY SSF52402 1 236 7.67E-56 T 31-10-2018 DFR85_14660 538f149d85e6e19a6cbb62860d9fc6bb 241 Pfam PF01012 Electron transfer flavoprotein domain 27 197 9.6E-36 T 31-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 DFR85_14660 538f149d85e6e19a6cbb62860d9fc6bb 241 Gene3D G3DSA:3.40.50.620 1 239 1.3E-56 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR85_14660 538f149d85e6e19a6cbb62860d9fc6bb 241 PIRSF PIRSF000090 1 241 2.0E-62 T 31-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 DFR85_14660 538f149d85e6e19a6cbb62860d9fc6bb 241 SMART SM00893 19 204 2.0E-36 T 31-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 DFR85_14625 a01aaf1c3bcd7ec4609c310f6b58ce59 396 Pfam PF02803 Thiolase, C-terminal domain 261 363 1.3E-7 T 31-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 DFR85_14625 a01aaf1c3bcd7ec4609c310f6b58ce59 396 Gene3D G3DSA:3.40.47.10 3 392 2.9E-120 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR85_14625 a01aaf1c3bcd7ec4609c310f6b58ce59 396 SUPERFAMILY SSF53901 230 388 1.05E-25 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR85_14625 a01aaf1c3bcd7ec4609c310f6b58ce59 396 Pfam PF00108 Thiolase, N-terminal domain 4 223 9.4E-25 T 31-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 DFR85_14625 a01aaf1c3bcd7ec4609c310f6b58ce59 396 SUPERFAMILY SSF53901 4 227 2.99E-46 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR85_14625 a01aaf1c3bcd7ec4609c310f6b58ce59 396 PIRSF PIRSF000429 1 389 4.7E-64 T 31-10-2018 IPR002155 Thiolase GO:0016747 DFR85_01050 75017252aca14ff3971fd7e1648d49b3 61 Pfam PF02294 7kD DNA-binding domain 4 61 1.1E-38 T 31-10-2018 IPR003212 DNA-binding 7kDa protein GO:0003677|GO:0004521 DFR85_01050 75017252aca14ff3971fd7e1648d49b3 61 SUPERFAMILY SSF54160 3 61 4.94E-32 T 31-10-2018 IPR016197 Chromo-like domain superfamily DFR85_01050 75017252aca14ff3971fd7e1648d49b3 61 ProDom PD010328 DNA-BINDING METHYLATION DIRECT SEQUENCING 3D-STRUCTURE A 7A 3.1.27.- P2 7D 10 61 3.0E-12 T 31-10-2018 IPR003212 DNA-binding 7kDa protein GO:0003677|GO:0004521 DFR85_01050 75017252aca14ff3971fd7e1648d49b3 61 Gene3D G3DSA:2.40.50.40 1 61 1.9E-34 T 31-10-2018 DFR85_09090 7e26ddc3042da7cf623960080bb8b05f 211 SUPERFAMILY SSF47979 64 137 2.88E-24 T 31-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 DFR85_09090 7e26ddc3042da7cf623960080bb8b05f 211 SMART SM00529 26 124 1.2E-35 T 31-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 DFR85_09090 7e26ddc3042da7cf623960080bb8b05f 211 Gene3D G3DSA:1.10.10.10 1 132 9.3E-43 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_09090 7e26ddc3042da7cf623960080bb8b05f 211 SMART SM00899 140 209 5.2E-4 T 31-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 DFR85_09090 7e26ddc3042da7cf623960080bb8b05f 211 SUPERFAMILY SSF50037 130 208 1.74E-8 T 31-10-2018 IPR008988 Transcriptional repressor, C-terminal DFR85_09090 7e26ddc3042da7cf623960080bb8b05f 211 SUPERFAMILY SSF46785 13 90 2.98E-12 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_09090 7e26ddc3042da7cf623960080bb8b05f 211 Pfam PF04023 FeoA domain 140 208 2.9E-5 T 31-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 DFR85_09090 7e26ddc3042da7cf623960080bb8b05f 211 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 4 54 1.4E-9 T 31-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 DFR85_09090 7e26ddc3042da7cf623960080bb8b05f 211 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 64 132 2.7E-27 T 31-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 DFR85_10465 f137976fc09a45cca94707d860185956 414 SMART SM01192 136 412 8.6E-149 T 31-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DFR85_10465 f137976fc09a45cca94707d860185956 414 SUPERFAMILY SSF51604 137 407 4.1E-102 T 31-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily DFR85_10465 f137976fc09a45cca94707d860185956 414 Hamap MF_00318 Enolase [eno]. 5 407 39.464 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DFR85_10465 f137976fc09a45cca94707d860185956 414 Gene3D G3DSA:3.30.390.10 4 124 1.4E-36 T 31-10-2018 IPR029017 Enolase-like, N-terminal DFR85_10465 f137976fc09a45cca94707d860185956 414 Pfam PF03952 Enolase, N-terminal domain 7 131 3.4E-39 T 31-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DFR85_10465 f137976fc09a45cca94707d860185956 414 Gene3D G3DSA:3.20.20.120 125 413 1.3E-114 T 31-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily DFR85_10465 f137976fc09a45cca94707d860185956 414 PIRSF PIRSF001400 3 413 1.1E-167 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DFR85_10465 f137976fc09a45cca94707d860185956 414 SMART SM01193 7 131 6.1E-52 T 31-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DFR85_10465 f137976fc09a45cca94707d860185956 414 Pfam PF00113 Enolase, C-terminal TIM barrel domain 138 407 9.4E-101 T 31-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DFR85_10465 f137976fc09a45cca94707d860185956 414 ProSitePatterns PS00164 Enolase signature. 330 343 - T 31-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR85_10465 f137976fc09a45cca94707d860185956 414 SUPERFAMILY SSF54826 6 134 2.36E-36 T 31-10-2018 DFR85_10465 f137976fc09a45cca94707d860185956 414 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 7 408 1.9E-149 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DFR85_10465 f137976fc09a45cca94707d860185956 414 PRINTS PR00148 Enolase signature 359 376 2.2E-37 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DFR85_10465 f137976fc09a45cca94707d860185956 414 PRINTS PR00148 Enolase signature 330 344 2.2E-37 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DFR85_10465 f137976fc09a45cca94707d860185956 414 PRINTS PR00148 Enolase signature 40 54 2.2E-37 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DFR85_10465 f137976fc09a45cca94707d860185956 414 PRINTS PR00148 Enolase signature 158 171 2.2E-37 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DFR85_10465 f137976fc09a45cca94707d860185956 414 PRINTS PR00148 Enolase signature 104 120 2.2E-37 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DFR85_10465 f137976fc09a45cca94707d860185956 414 PRINTS PR00148 Enolase signature 307 318 2.2E-37 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DFR85_13405 23fb81a7e6ce317193641dc0ea25e2aa 62 SUPERFAMILY SSF57667 8 53 6.75E-6 T 31-10-2018 IPR036236 Zinc finger C2H2 superfamily DFR85_13405 23fb81a7e6ce317193641dc0ea25e2aa 62 SMART SM00355 35 58 3.2 T 31-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 DFR85_13405 23fb81a7e6ce317193641dc0ea25e2aa 62 SMART SM00355 9 33 0.027 T 31-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 DFR85_13405 23fb81a7e6ce317193641dc0ea25e2aa 62 Gene3D G3DSA:3.30.160.60 8 59 7.2E-10 T 31-10-2018 DFR85_13405 23fb81a7e6ce317193641dc0ea25e2aa 62 ProSitePatterns PS00028 Zinc finger C2H2 type domain signature. 11 33 - T 31-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 DFR85_13405 23fb81a7e6ce317193641dc0ea25e2aa 62 Pfam PF00096 Zinc finger, C2H2 type 36 58 0.01 T 31-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 DFR85_13405 23fb81a7e6ce317193641dc0ea25e2aa 62 Pfam PF00096 Zinc finger, C2H2 type 9 33 1.3E-4 T 31-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 DFR85_01460 1e7b593e54645a1fe3c8b11432fae938 223 Gene3D G3DSA:1.10.150.660 15 93 3.0E-68 T 31-10-2018 DFR85_01460 1e7b593e54645a1fe3c8b11432fae938 223 SUPERFAMILY SSF56784 3 216 8.99E-31 T 31-10-2018 IPR036412 HAD-like superfamily DFR85_01460 1e7b593e54645a1fe3c8b11432fae938 223 Pfam PF13419 Haloacid dehalogenase-like hydrolase 37 190 2.6E-13 T 31-10-2018 DFR85_01460 1e7b593e54645a1fe3c8b11432fae938 223 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 83 184 1.3E-9 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 DFR85_01460 1e7b593e54645a1fe3c8b11432fae938 223 Gene3D G3DSA:3.40.50.1000 4 212 3.0E-68 T 31-10-2018 IPR023214 HAD superfamily DFR85_11825 b8923c90316361f172f0a7d305f9118d 238 SUPERFAMILY SSF54631 118 236 9.39E-24 T 31-10-2018 DFR85_11825 b8923c90316361f172f0a7d305f9118d 238 Gene3D G3DSA:3.10.580.10 119 236 1.9E-24 T 31-10-2018 DFR85_11825 b8923c90316361f172f0a7d305f9118d 238 SUPERFAMILY SSF54631 1 115 8.66E-26 T 31-10-2018 DFR85_11825 b8923c90316361f172f0a7d305f9118d 238 Gene3D G3DSA:3.10.580.10 1 118 3.3E-28 T 31-10-2018 DFR85_11825 b8923c90316361f172f0a7d305f9118d 238 Pfam PF00571 CBS domain 119 170 5.7E-7 T 31-10-2018 IPR000644 CBS domain DFR85_11825 b8923c90316361f172f0a7d305f9118d 238 Pfam PF00571 CBS domain 58 111 2.3E-10 T 31-10-2018 IPR000644 CBS domain DFR85_11825 b8923c90316361f172f0a7d305f9118d 238 Pfam PF00571 CBS domain 183 236 1.8E-10 T 31-10-2018 IPR000644 CBS domain DFR85_11825 b8923c90316361f172f0a7d305f9118d 238 Pfam PF00571 CBS domain 3 48 8.2E-9 T 31-10-2018 IPR000644 CBS domain DFR85_11825 b8923c90316361f172f0a7d305f9118d 238 SMART SM00116 190 237 3.1E-6 T 31-10-2018 IPR000644 CBS domain DFR85_11825 b8923c90316361f172f0a7d305f9118d 238 SMART SM00116 65 112 6.7E-6 T 31-10-2018 IPR000644 CBS domain DFR85_11825 b8923c90316361f172f0a7d305f9118d 238 SMART SM00116 126 173 0.05 T 31-10-2018 IPR000644 CBS domain DFR85_11825 b8923c90316361f172f0a7d305f9118d 238 SMART SM00116 10 52 0.015 T 31-10-2018 IPR000644 CBS domain DFR85_10940 916b335b56a2e3b4f74f7a82574c9fe9 379 Gene3D G3DSA:3.40.50.2000 25 207 4.2E-6 T 31-10-2018 DFR85_10940 916b335b56a2e3b4f74f7a82574c9fe9 379 Gene3D G3DSA:3.40.50.2000 208 368 1.1E-26 T 31-10-2018 DFR85_10940 916b335b56a2e3b4f74f7a82574c9fe9 379 SUPERFAMILY SSF53756 28 377 8.64E-43 T 31-10-2018 DFR85_10940 916b335b56a2e3b4f74f7a82574c9fe9 379 Pfam PF00534 Glycosyl transferases group 1 207 354 6.3E-27 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 DFR85_14530 5b5f01c663b3f35567f6b48278dc61a5 358 Gene3D G3DSA:1.10.8.60 208 285 8.3E-30 T 31-10-2018 DFR85_14530 5b5f01c663b3f35567f6b48278dc61a5 358 SUPERFAMILY SSF46785 289 357 1.6E-12 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_14530 5b5f01c663b3f35567f6b48278dc61a5 358 Gene3D G3DSA:3.40.50.300 1 207 6.0E-48 T 31-10-2018 DFR85_14530 5b5f01c663b3f35567f6b48278dc61a5 358 Pfam PF01637 ATPase domain predominantly from Archaea 14 248 3.4E-25 T 31-10-2018 IPR011579 ATPase domain GO:0005524 DFR85_14530 5b5f01c663b3f35567f6b48278dc61a5 358 Gene3D G3DSA:1.10.10.10 286 358 2.1E-26 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_14530 5b5f01c663b3f35567f6b48278dc61a5 358 SUPERFAMILY SSF52540 3 282 1.43E-49 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_03640 1432966d6c50f9d958c626ec8c747ddf 312 SUPERFAMILY SSF51735 7 256 8.0E-25 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_03640 1432966d6c50f9d958c626ec8c747ddf 312 Gene3D G3DSA:3.40.50.720 7 288 2.8E-24 T 31-10-2018 DFR85_03640 1432966d6c50f9d958c626ec8c747ddf 312 Pfam PF01370 NAD dependent epimerase/dehydratase family 9 173 3.3E-13 T 31-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 DFR85_03770 6ab5eb49d3e28c08961a1d29065979d0 418 PIRSF PIRSF000310 219 417 2.1E-42 T 31-10-2018 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 DFR85_03770 6ab5eb49d3e28c08961a1d29065979d0 418 PIRSF PIRSF000310 1 177 3.6E-31 T 31-10-2018 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 DFR85_03770 6ab5eb49d3e28c08961a1d29065979d0 418 SUPERFAMILY SSF56770 40 376 3.53E-54 T 31-10-2018 DFR85_03770 6ab5eb49d3e28c08961a1d29065979d0 418 Gene3D G3DSA:4.10.480.10 296 404 9.0E-24 T 31-10-2018 IPR037148 [NiFe]-hydrogenase, small subunit, C-terminal domain superfamily DFR85_03770 6ab5eb49d3e28c08961a1d29065979d0 418 Gene3D G3DSA:3.40.50.700 35 211 1.2E-33 T 31-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily DFR85_03770 6ab5eb49d3e28c08961a1d29065979d0 418 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 51 270 6.2E-15 T 31-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_03770 6ab5eb49d3e28c08961a1d29065979d0 418 Pfam PF14720 NiFe/NiFeSe hydrogenase small subunit C-terminal 294 374 3.3E-23 T 31-10-2018 IPR027394 Cytochrome-c3 hydrogenase, C-terminal DFR85_03770 6ab5eb49d3e28c08961a1d29065979d0 418 Gene3D G3DSA:3.40.50.700 218 293 5.4E-6 T 31-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily DFR85_08390 0f2d879fe25b29e08247c629fcc2baed 211 Pfam PF10007 Uncharacterized protein conserved in archaea (DUF2250) 11 101 3.1E-36 T 31-10-2018 IPR019254 Protein of unknown function DUF2250 DFR85_08390 0f2d879fe25b29e08247c629fcc2baed 211 Pfam PF10007 Uncharacterized protein conserved in archaea (DUF2250) 112 203 3.5E-31 T 31-10-2018 IPR019254 Protein of unknown function DUF2250 DFR85_08390 0f2d879fe25b29e08247c629fcc2baed 211 Gene3D G3DSA:1.10.10.10 12 110 3.8E-5 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_08390 0f2d879fe25b29e08247c629fcc2baed 211 PIRSF PIRSF037213 1 211 1.3E-65 T 31-10-2018 IPR017139 Uncharacterised conserved protein UCP037213 DFR85_12660 c33474af1242f8188b5fd2e4b6aad2fb 249 SUPERFAMILY SSF51735 6 235 2.8E-67 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_12660 c33474af1242f8188b5fd2e4b6aad2fb 249 Gene3D G3DSA:3.40.50.720 1 243 1.0E-66 T 31-10-2018 DFR85_12660 c33474af1242f8188b5fd2e4b6aad2fb 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 232 3.7E-48 T 31-10-2018 DFR85_12660 c33474af1242f8188b5fd2e4b6aad2fb 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 126 134 8.7E-10 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_12660 c33474af1242f8188b5fd2e4b6aad2fb 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 165 8.7E-10 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_12660 c33474af1242f8188b5fd2e4b6aad2fb 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 8.7E-10 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_12660 c33474af1242f8188b5fd2e4b6aad2fb 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 197 217 3.7E-33 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_12660 c33474af1242f8188b5fd2e4b6aad2fb 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 3.7E-33 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_12660 c33474af1242f8188b5fd2e4b6aad2fb 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 3.7E-33 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_12660 c33474af1242f8188b5fd2e4b6aad2fb 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.7E-33 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_12660 c33474af1242f8188b5fd2e4b6aad2fb 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 3.7E-33 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_12660 c33474af1242f8188b5fd2e4b6aad2fb 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 3.7E-33 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_08535 a4df92846f399ad48e7fc531078135f5 407 PRINTS PR00758 Arsenical pump membrane protein signature 267 291 1.6E-5 T 31-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 DFR85_08535 a4df92846f399ad48e7fc531078135f5 407 PRINTS PR00758 Arsenical pump membrane protein signature 100 124 1.6E-5 T 31-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 DFR85_08535 a4df92846f399ad48e7fc531078135f5 407 Pfam PF03600 Citrate transporter 21 346 9.1E-36 T 31-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 DFR85_06010 54058bc990a74a29d463e5a5a8eb1f50 267 Gene3D G3DSA:3.40.50.1580 2 267 5.2E-100 T 31-10-2018 DFR85_06010 54058bc990a74a29d463e5a5a8eb1f50 267 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 7 267 43.737 T 31-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 DFR85_06010 54058bc990a74a29d463e5a5a8eb1f50 267 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 55 95 - T 31-10-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 DFR85_06010 54058bc990a74a29d463e5a5a8eb1f50 267 Pfam PF01048 Phosphorylase superfamily 8 246 5.1E-47 T 31-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 DFR85_06010 54058bc990a74a29d463e5a5a8eb1f50 267 SUPERFAMILY SSF53167 7 265 1.17E-92 T 31-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 DFR85_06010 54058bc990a74a29d463e5a5a8eb1f50 267 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 9 247 9.8E-102 T 31-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 DFR85_14720 30480e6466532a94b4839391d8383195 545 Pfam PF13450 NAD(P)-binding Rossmann-like domain 363 403 5.5E-9 T 31-10-2018 DFR85_14720 30480e6466532a94b4839391d8383195 545 Gene3D G3DSA:3.20.20.70 1 344 4.5E-101 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_14720 30480e6466532a94b4839391d8383195 545 Gene3D G3DSA:3.40.50.720 361 434 1.4E-21 T 31-10-2018 DFR85_14720 30480e6466532a94b4839391d8383195 545 SUPERFAMILY SSF51395 2 350 1.91E-96 T 31-10-2018 DFR85_14720 30480e6466532a94b4839391d8383195 545 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 2 319 3.4E-58 T 31-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 DFR85_14720 30480e6466532a94b4839391d8383195 545 SUPERFAMILY SSF51971 321 439 5.89E-17 T 31-10-2018 DFR85_08320 2aa39aede12b2fbb93bad1c8409e8149 684 SMART SM00382 330 482 9.0E-4 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_08320 2aa39aede12b2fbb93bad1c8409e8149 684 Pfam PF00493 MCM2/3/5 family 276 592 3.9E-132 T 31-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 DFR85_08320 2aa39aede12b2fbb93bad1c8409e8149 684 Gene3D G3DSA:2.20.28.10 137 183 1.2E-23 T 31-10-2018 DFR85_08320 2aa39aede12b2fbb93bad1c8409e8149 684 Pfam PF14551 MCM N-terminal domain 11 140 6.2E-15 T 31-10-2018 IPR027925 MCM N-terminal domain Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962|Reactome: R-HSA-69052 DFR85_08320 2aa39aede12b2fbb93bad1c8409e8149 684 SUPERFAMILY SSF52540 298 592 6.85E-42 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_08320 2aa39aede12b2fbb93bad1c8409e8149 684 SMART SM00350 102 596 1.9E-203 T 31-10-2018 IPR031327 Mini-chromosome maintenance protein DFR85_08320 2aa39aede12b2fbb93bad1c8409e8149 684 Gene3D G3DSA:3.40.50.300 272 600 1.4E-132 T 31-10-2018 DFR85_08320 2aa39aede12b2fbb93bad1c8409e8149 684 Gene3D G3DSA:3.30.1640.10 1 102 5.1E-22 T 31-10-2018 DFR85_08320 2aa39aede12b2fbb93bad1c8409e8149 684 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 417 430 4.6E-31 T 31-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 DFR85_08320 2aa39aede12b2fbb93bad1c8409e8149 684 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 329 344 4.6E-31 T 31-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 DFR85_08320 2aa39aede12b2fbb93bad1c8409e8149 684 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 441 453 4.6E-31 T 31-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 DFR85_08320 2aa39aede12b2fbb93bad1c8409e8149 684 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 389 403 4.6E-31 T 31-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 DFR85_08320 2aa39aede12b2fbb93bad1c8409e8149 684 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 468 476 4.6E-31 T 31-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 DFR85_08320 2aa39aede12b2fbb93bad1c8409e8149 684 SUPERFAMILY SSF50249 10 256 2.06E-62 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR85_08320 2aa39aede12b2fbb93bad1c8409e8149 684 Pfam PF17207 MCM OB domain 106 237 6.5E-35 T 31-10-2018 IPR033762 MCM OB domain Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 DFR85_08320 2aa39aede12b2fbb93bad1c8409e8149 684 Gene3D G3DSA:1.10.10.10 601 684 2.6E-28 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_09170 658f1f3377bf76c01aba9c9e614548e5 257 Gene3D G3DSA:3.90.226.10 1 199 1.8E-75 T 31-10-2018 DFR85_09170 658f1f3377bf76c01aba9c9e614548e5 257 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 98 118 - T 31-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 DFR85_09170 658f1f3377bf76c01aba9c9e614548e5 257 Pfam PF00378 Enoyl-CoA hydratase/isomerase 8 256 1.5E-71 T 31-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 DFR85_09170 658f1f3377bf76c01aba9c9e614548e5 257 Gene3D G3DSA:1.10.12.10 200 257 4.6E-16 T 31-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal DFR85_09170 658f1f3377bf76c01aba9c9e614548e5 257 SUPERFAMILY SSF52096 1 256 9.8E-89 T 31-10-2018 IPR029045 ClpP/crotonase-like domain superfamily DFR85_14275 c3ec36cf7e033d5c885e7169b95d94ac 130 Pfam PF01850 PIN domain 8 118 1.5E-5 T 31-10-2018 IPR002716 PIN domain DFR85_14275 c3ec36cf7e033d5c885e7169b95d94ac 130 Gene3D G3DSA:3.40.50.1010 1 130 8.0E-30 T 31-10-2018 DFR85_14275 c3ec36cf7e033d5c885e7169b95d94ac 130 SUPERFAMILY SSF88723 6 121 3.36E-15 T 31-10-2018 IPR029060 PIN-like domain superfamily DFR85_08140 13d78d9aa8db8dfb30b15725b9ba3698 316 Pfam PF10120 Thiamine-phosphate synthase 144 300 5.2E-46 T 31-10-2018 IPR019293 Thiamine-phosphate synthase ThiN GO:0004789 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 DFR85_08140 13d78d9aa8db8dfb30b15725b9ba3698 316 SUPERFAMILY SSF53639 135 308 5.49E-46 T 31-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily DFR85_08140 13d78d9aa8db8dfb30b15725b9ba3698 316 Gene3D G3DSA:3.40.225.10 132 314 1.7E-43 T 31-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily DFR85_02515 efe4d30f2f190cb233706afc7042f8ed 559 Pfam PF01979 Amidohydrolase family 128 448 7.9E-57 T 31-10-2018 IPR006680 Amidohydrolase-related GO:0016787 DFR85_02515 efe4d30f2f190cb233706afc7042f8ed 559 TIGRFAM TIGR01792 urease_alph: urease, alpha subunit 4 559 1.4E-245 T 31-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 DFR85_02515 efe4d30f2f190cb233706afc7042f8ed 559 Gene3D G3DSA:2.30.40.10 5 477 2.5E-248 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR85_02515 efe4d30f2f190cb233706afc7042f8ed 559 SUPERFAMILY SSF51556 132 559 7.49E-166 T 31-10-2018 IPR032466 Metal-dependent hydrolase DFR85_02515 efe4d30f2f190cb233706afc7042f8ed 559 Gene3D G3DSA:3.20.20.140 132 559 2.5E-248 T 31-10-2018 DFR85_02515 efe4d30f2f190cb233706afc7042f8ed 559 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 297 314 4.5E-29 T 31-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 DFR85_02515 efe4d30f2f190cb233706afc7042f8ed 559 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 336 352 4.5E-29 T 31-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 DFR85_02515 efe4d30f2f190cb233706afc7042f8ed 559 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 424 437 4.5E-29 T 31-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 DFR85_02515 efe4d30f2f190cb233706afc7042f8ed 559 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 398 413 4.5E-29 T 31-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 DFR85_02515 efe4d30f2f190cb233706afc7042f8ed 559 SUPERFAMILY SSF51338 3 471 3.34E-51 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR85_02515 efe4d30f2f190cb233706afc7042f8ed 559 Hamap MF_01953 Urease subunit alpha [ureC]. 3 559 51.065 T 31-10-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 DFR85_02515 efe4d30f2f190cb233706afc7042f8ed 559 Pfam PF00449 Urease alpha-subunit, N-terminal domain 4 122 2.5E-48 T 31-10-2018 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 DFR85_12050 243251356b9384ed25f97b40a0ec4e8c 309 Pfam PF16363 GDP-mannose 4,6 dehydratase 1 271 4.0E-67 T 31-10-2018 IPR016040 NAD(P)-binding domain DFR85_12050 243251356b9384ed25f97b40a0ec4e8c 309 SUPERFAMILY SSF51735 2 297 2.21E-83 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_12050 243251356b9384ed25f97b40a0ec4e8c 309 Gene3D G3DSA:3.90.25.10 175 291 2.5E-103 T 31-10-2018 DFR85_12050 243251356b9384ed25f97b40a0ec4e8c 309 Gene3D G3DSA:3.40.50.720 1 282 2.5E-103 T 31-10-2018 DFR85_12050 243251356b9384ed25f97b40a0ec4e8c 309 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 1 297 4.4E-116 T 31-10-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 DFR85_00505 ef1a88cec157ec5b69b926df5f6a82af 439 SUPERFAMILY SSF50998 67 422 4.6E-40 T 31-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily DFR85_00505 ef1a88cec157ec5b69b926df5f6a82af 439 Pfam PF13360 PQQ-like domain 108 314 6.4E-14 T 31-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat DFR85_00505 ef1a88cec157ec5b69b926df5f6a82af 439 Gene3D G3DSA:2.130.10.10 52 430 1.1E-42 T 31-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 DFR85_00505 ef1a88cec157ec5b69b926df5f6a82af 439 SMART SM00564 184 216 0.17 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DFR85_00505 ef1a88cec157ec5b69b926df5f6a82af 439 SMART SM00564 79 125 460.0 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DFR85_00505 ef1a88cec157ec5b69b926df5f6a82af 439 SMART SM00564 132 176 1.1 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DFR85_00505 ef1a88cec157ec5b69b926df5f6a82af 439 SMART SM00564 331 364 1.6 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DFR85_00505 ef1a88cec157ec5b69b926df5f6a82af 439 SMART SM00564 226 258 1.9 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DFR85_00505 ef1a88cec157ec5b69b926df5f6a82af 439 SMART SM00564 275 317 69.0 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DFR85_09035 8bc7dae1123a5a86ec38992c8336e00f 412 Gene3D G3DSA:3.20.20.140 57 340 3.2E-92 T 31-10-2018 DFR85_09035 8bc7dae1123a5a86ec38992c8336e00f 412 SUPERFAMILY SSF51556 56 338 1.1E-68 T 31-10-2018 IPR032466 Metal-dependent hydrolase DFR85_09035 8bc7dae1123a5a86ec38992c8336e00f 412 SUPERFAMILY SSF51338 8 394 2.34E-17 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR85_09035 8bc7dae1123a5a86ec38992c8336e00f 412 Gene3D G3DSA:2.30.40.10 27 392 3.2E-92 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR85_09035 8bc7dae1123a5a86ec38992c8336e00f 412 Pfam PF01979 Amidohydrolase family 53 388 4.3E-56 T 31-10-2018 IPR006680 Amidohydrolase-related GO:0016787 DFR85_07290 575c59b1f37340bcbe1ecff85b49f250 61 Gene3D G3DSA:2.20.25.30 1 55 5.7E-24 T 31-10-2018 IPR011331 Ribosomal protein L37ae/L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_07290 575c59b1f37340bcbe1ecff85b49f250 61 Pfam PF01907 Ribosomal protein L37e 1 54 7.9E-26 T 31-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07290 575c59b1f37340bcbe1ecff85b49f250 61 ProSitePatterns PS01077 Ribosomal protein L37e signature. 3 23 - T 31-10-2018 IPR018267 Ribosomal protein L37e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07290 575c59b1f37340bcbe1ecff85b49f250 61 Hamap MF_00547 50S ribosomal protein L37e [rpl37e]. 1 54 20.841 T 31-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07290 575c59b1f37340bcbe1ecff85b49f250 61 SUPERFAMILY SSF57829 1 55 2.38E-22 T 31-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 DFR85_07290 575c59b1f37340bcbe1ecff85b49f250 61 ProDom PD005132 RIBOSOMAL RRNA-BINDING METAL-BINDING RNA-BINDING ZINC RIBONUCLEOPROTEIN ZINC-FINGER L37 60S L37E 8 50 6.0E-15 T 31-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_08655 c0d256d714662af24bfeb7b97c1b966d 871 Gene3D G3DSA:3.40.50.300 250 414 3.2E-24 T 31-10-2018 DFR85_08655 c0d256d714662af24bfeb7b97c1b966d 871 PIRSF PIRSF037307 3 869 6.5E-273 T 31-10-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 DFR85_08655 c0d256d714662af24bfeb7b97c1b966d 871 Pfam PF00271 Helicase conserved C-terminal domain 269 375 2.5E-15 T 31-10-2018 IPR001650 Helicase, C-terminal DFR85_08655 c0d256d714662af24bfeb7b97c1b966d 871 SUPERFAMILY SSF52540 41 379 9.96E-45 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_08655 c0d256d714662af24bfeb7b97c1b966d 871 Gene3D G3DSA:3.40.50.300 11 237 3.8E-48 T 31-10-2018 DFR85_08655 c0d256d714662af24bfeb7b97c1b966d 871 SMART SM00490 293 375 1.9E-13 T 31-10-2018 IPR001650 Helicase, C-terminal DFR85_08655 c0d256d714662af24bfeb7b97c1b966d 871 SMART SM00487 28 244 2.6E-32 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain DFR85_08655 c0d256d714662af24bfeb7b97c1b966d 871 Pfam PF00270 DEAD/DEAH box helicase 33 214 3.5E-27 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 DFR85_08655 c0d256d714662af24bfeb7b97c1b966d 871 Pfam PF08494 DEAD/H associated 636 825 6.4E-52 T 31-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 DFR85_09830 d57f66cea4ca49e00831cb4ff49e16f4 273 SUPERFAMILY SSF52518 10 259 1.79E-71 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR85_09830 d57f66cea4ca49e00831cb4ff49e16f4 273 Gene3D G3DSA:3.40.50.970 11 270 3.2E-76 T 31-10-2018 DFR85_09830 d57f66cea4ca49e00831cb4ff49e16f4 273 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 38 258 3.1E-31 T 31-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 DFR85_09710 70782e275cc0e2148dbb2aacfaaddec2 253 SUPERFAMILY SSF69796 1 205 1.31E-61 T 31-10-2018 IPR036098 Thymidylate synthase ThyX superfamily GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 DFR85_09710 70782e275cc0e2148dbb2aacfaaddec2 253 Pfam PF02511 Thymidylate synthase complementing protein 5 193 1.8E-64 T 31-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 DFR85_09710 70782e275cc0e2148dbb2aacfaaddec2 253 Hamap MF_01408 Flavin-dependent thymidylate synthase [thyX]. 1 207 30.55 T 31-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 DFR85_09710 70782e275cc0e2148dbb2aacfaaddec2 253 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 3 198 6.1E-63 T 31-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 DFR85_09710 70782e275cc0e2148dbb2aacfaaddec2 253 Gene3D G3DSA:3.30.1360.170 1 205 1.1E-63 T 31-10-2018 DFR85_05495 c833b984dc5ad7bedad92e3284de561f 97 SUPERFAMILY SSF54909 1 95 2.98E-22 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel DFR85_05495 c833b984dc5ad7bedad92e3284de561f 97 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 73 3.9E-12 T 31-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain DFR85_05495 c833b984dc5ad7bedad92e3284de561f 97 Gene3D G3DSA:3.30.70.100 6 95 1.2E-13 T 31-10-2018 DFR85_11315 0e1309c3257f753600755dc8c80e7e3e 239 Pfam PF01048 Phosphorylase superfamily 17 231 1.2E-34 T 31-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 DFR85_11315 0e1309c3257f753600755dc8c80e7e3e 239 SUPERFAMILY SSF53167 4 235 3.14E-68 T 31-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 DFR85_11315 0e1309c3257f753600755dc8c80e7e3e 239 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 61 76 - T 31-10-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 DFR85_11315 0e1309c3257f753600755dc8c80e7e3e 239 Gene3D G3DSA:3.40.50.1580 1 236 8.7E-73 T 31-10-2018 DFR85_06000 d72f154784224ddd7165ac10a28e473a 361 Gene3D G3DSA:3.30.420.60 129 264 6.2E-43 T 31-10-2018 DFR85_06000 d72f154784224ddd7165ac10a28e473a 361 Pfam PF03464 eRF1 domain 2 132 264 3.3E-41 T 31-10-2018 IPR005141 eRF1 domain 2 DFR85_06000 d72f154784224ddd7165ac10a28e473a 361 Gene3D G3DSA:3.30.1330.30 265 361 6.0E-25 T 31-10-2018 IPR029064 50S ribosomal protein L30e-like DFR85_06000 d72f154784224ddd7165ac10a28e473a 361 Hamap MF_00424 Peptide chain release factor subunit 1 [prf1]. 13 361 40.268 T 31-10-2018 IPR020918 Peptide chain release factor aRF1 GO:0003747|GO:0005737|GO:0006415 DFR85_06000 d72f154784224ddd7165ac10a28e473a 361 SUPERFAMILY SSF55481 3 128 2.09E-39 T 31-10-2018 IPR024049 Peptide Chain Release Factor eRF1/aRF1, N-terminal Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_06000 d72f154784224ddd7165ac10a28e473a 361 Gene3D G3DSA:3.30.960.10 1 128 9.6E-44 T 31-10-2018 IPR024049 Peptide Chain Release Factor eRF1/aRF1, N-terminal Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_06000 d72f154784224ddd7165ac10a28e473a 361 TIGRFAM TIGR03676 aRF1/eRF1: peptide chain release factor 1, archaeal and eukaryotic forms 3 313 6.1E-123 T 31-10-2018 IPR004403 Peptide chain release factor eRF1/aRF1 GO:0003747|GO:0005737|GO:0006415 Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_06000 d72f154784224ddd7165ac10a28e473a 361 Pfam PF03465 eRF1 domain 3 269 360 1.0E-18 T 31-10-2018 IPR005142 eRF1 domain 3 DFR85_06000 d72f154784224ddd7165ac10a28e473a 361 SMART SM01194 2 127 5.8E-28 T 31-10-2018 IPR005140 eRF1 domain 1/Pelota-like DFR85_06000 d72f154784224ddd7165ac10a28e473a 361 SUPERFAMILY SSF53137 130 263 8.72E-38 T 31-10-2018 DFR85_06000 d72f154784224ddd7165ac10a28e473a 361 SUPERFAMILY SSF55315 266 360 1.32E-21 T 31-10-2018 IPR029064 50S ribosomal protein L30e-like DFR85_00550 4165102a9337fdf88da028c9828b4e33 90 Gene3D G3DSA:3.30.70.260 1 90 1.5E-26 T 31-10-2018 DFR85_00550 4165102a9337fdf88da028c9828b4e33 90 Hamap MF_01054 UPF0237 protein . 2 90 25.248 T 31-10-2018 IPR022986 Uncharacterised protein family UPF0237, ACT-type DFR85_00550 4165102a9337fdf88da028c9828b4e33 90 Pfam PF13740 ACT domain 3 76 3.3E-17 T 31-10-2018 DFR85_00550 4165102a9337fdf88da028c9828b4e33 90 SUPERFAMILY SSF55021 3 82 1.11E-20 T 31-10-2018 DFR85_11790 1b1b56f0ded042b5b1ff24f000b736d6 528 Gene3D G3DSA:1.20.1740.10 18 516 4.7E-23 T 31-10-2018 DFR85_11790 1b1b56f0ded042b5b1ff24f000b736d6 528 PIRSF PIRSF006060 2 523 3.4E-63 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_11790 1b1b56f0ded042b5b1ff24f000b736d6 528 Pfam PF13520 Amino acid permease 43 476 9.2E-25 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_12510 af487a76e1d4a3131a85af6a2ee16e86 691 Gene3D G3DSA:3.40.50.300 438 686 1.1E-86 T 31-10-2018 DFR85_12510 af487a76e1d4a3131a85af6a2ee16e86 691 SUPERFAMILY SSF90123 106 431 6.8E-77 T 31-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 DFR85_12510 af487a76e1d4a3131a85af6a2ee16e86 691 Pfam PF00005 ABC transporter 458 607 3.6E-34 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR85_12510 af487a76e1d4a3131a85af6a2ee16e86 691 ProSitePatterns PS00211 ABC transporters family signature. 579 593 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DFR85_12510 af487a76e1d4a3131a85af6a2ee16e86 691 SUPERFAMILY SSF52540 432 675 1.41E-82 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_12510 af487a76e1d4a3131a85af6a2ee16e86 691 Gene3D G3DSA:1.20.1560.10 93 429 1.8E-83 T 31-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 DFR85_12510 af487a76e1d4a3131a85af6a2ee16e86 691 SMART SM00382 467 653 7.8E-15 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_12510 af487a76e1d4a3131a85af6a2ee16e86 691 Pfam PF00664 ABC transporter transmembrane region 127 396 9.1E-39 T 31-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 DFR85_08665 6a3360ddb3aa105bd0c8398235fb6276 300 Pfam PF03444 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 3 79 2.1E-34 T 31-10-2018 IPR005104 Winged helix-turn-helix transcription repressor, HrcA DNA-binding domain GO:0003677|GO:0006355 DFR85_08665 6a3360ddb3aa105bd0c8398235fb6276 300 SUPERFAMILY SSF46785 4 77 1.57E-11 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_08665 6a3360ddb3aa105bd0c8398235fb6276 300 SMART SM00116 181 229 1.1E-8 T 31-10-2018 IPR000644 CBS domain DFR85_08665 6a3360ddb3aa105bd0c8398235fb6276 300 SMART SM00116 244 292 1.7E-13 T 31-10-2018 IPR000644 CBS domain DFR85_08665 6a3360ddb3aa105bd0c8398235fb6276 300 PIRSF PIRSF005063 1 299 4.9E-121 T 31-10-2018 IPR016436 Uncharacterised conserved protein UCP005063, CBS-type DFR85_08665 6a3360ddb3aa105bd0c8398235fb6276 300 SUPERFAMILY SSF54631 170 292 1.26E-32 T 31-10-2018 DFR85_08665 6a3360ddb3aa105bd0c8398235fb6276 300 Gene3D G3DSA:3.10.580.10 231 293 3.7E-16 T 31-10-2018 DFR85_08665 6a3360ddb3aa105bd0c8398235fb6276 300 Gene3D G3DSA:3.10.580.10 144 230 1.1E-13 T 31-10-2018 DFR85_08665 6a3360ddb3aa105bd0c8398235fb6276 300 Gene3D G3DSA:1.10.10.10 10 73 1.7E-6 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_08665 6a3360ddb3aa105bd0c8398235fb6276 300 Pfam PF00571 CBS domain 174 228 3.6E-9 T 31-10-2018 IPR000644 CBS domain DFR85_08665 6a3360ddb3aa105bd0c8398235fb6276 300 Pfam PF00571 CBS domain 237 292 1.4E-12 T 31-10-2018 IPR000644 CBS domain DFR85_10130 d4d7d62a7af67a027ccd6c98480a6a09 51 Hamap MF_00629 50S ribosomal protein L39e [rpl39e]. 1 51 16.771 T 31-10-2018 IPR000077 Ribosomal protein L39e GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_10130 d4d7d62a7af67a027ccd6c98480a6a09 51 SUPERFAMILY SSF48662 4 51 2.09E-16 T 31-10-2018 IPR023626 Ribosomal protein L39e domain superfamily DFR85_10130 d4d7d62a7af67a027ccd6c98480a6a09 51 Gene3D G3DSA:1.10.1620.10 2 50 1.4E-16 T 31-10-2018 IPR023626 Ribosomal protein L39e domain superfamily DFR85_10130 d4d7d62a7af67a027ccd6c98480a6a09 51 Pfam PF00832 Ribosomal L39 protein 9 50 2.9E-17 T 31-10-2018 IPR000077 Ribosomal protein L39e GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_08970 1d3fb1c0c24d675c3b97dca607507a09 592 SUPERFAMILY SSF81442 19 489 4.06E-93 T 31-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_08970 1d3fb1c0c24d675c3b97dca607507a09 592 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 20 467 4.7E-74 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_08970 1d3fb1c0c24d675c3b97dca607507a09 592 PRINTS PR01165 Cytochrome c oxidase subunit I signature 238 259 1.5E-9 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_08970 1d3fb1c0c24d675c3b97dca607507a09 592 PRINTS PR01165 Cytochrome c oxidase subunit I signature 422 443 1.5E-9 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_08970 1d3fb1c0c24d675c3b97dca607507a09 592 PRINTS PR01165 Cytochrome c oxidase subunit I signature 371 390 1.5E-9 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_08970 1d3fb1c0c24d675c3b97dca607507a09 592 PRINTS PR01165 Cytochrome c oxidase subunit I signature 308 329 1.5E-9 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_08970 1d3fb1c0c24d675c3b97dca607507a09 592 Gene3D G3DSA:1.20.210.10 12 527 2.6E-81 T 31-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_05405 962bb9ea9363678e9e021c2fcf7edbd2 496 Pfam PF13520 Amino acid permease 26 444 2.3E-22 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_05405 962bb9ea9363678e9e021c2fcf7edbd2 496 Gene3D G3DSA:1.20.1740.10 25 481 2.8E-7 T 31-10-2018 DFR85_05405 962bb9ea9363678e9e021c2fcf7edbd2 496 PIRSF PIRSF006060 1 494 4.7E-35 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_03530 5abd0b08eb7f16ffe738fbd6ab6a4a92 248 Pfam PF04016 Putative heavy-metal chelation 99 232 2.1E-39 T 31-10-2018 IPR007161 Putative heavy-metal chelation domain DFR85_03530 5abd0b08eb7f16ffe738fbd6ab6a4a92 248 Gene3D G3DSA:3.30.390.100 15 216 2.6E-44 T 31-10-2018 DFR85_03530 5abd0b08eb7f16ffe738fbd6ab6a4a92 248 Gene3D G3DSA:3.40.50.11590 103 214 2.6E-44 T 31-10-2018 DFR85_03530 5abd0b08eb7f16ffe738fbd6ab6a4a92 248 Pfam PF13938 Putative heavy-metal chelation 6 88 1.6E-19 T 31-10-2018 IPR025251 Domain of unknown function DUF4213 DFR85_03530 5abd0b08eb7f16ffe738fbd6ab6a4a92 248 SUPERFAMILY SSF159713 4 232 3.01E-55 T 31-10-2018 DFR85_01825 f4a6b03a4469ed66dcbbee3c12b578c6 239 Gene3D G3DSA:3.40.50.300 1 238 6.0E-70 T 31-10-2018 DFR85_01825 f4a6b03a4469ed66dcbbee3c12b578c6 239 SMART SM00382 28 206 6.6E-12 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_01825 f4a6b03a4469ed66dcbbee3c12b578c6 239 Pfam PF00005 ABC transporter 19 157 1.6E-30 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR85_01825 f4a6b03a4469ed66dcbbee3c12b578c6 239 SUPERFAMILY SSF52540 3 221 8.44E-64 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_09790 f3a1accc742e862fbf1849df9f98af01 391 ProSitePatterns PS00104 EPSP synthase signature 1. 62 76 - T 31-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 DFR85_09790 f3a1accc742e862fbf1849df9f98af01 391 SUPERFAMILY SSF55205 7 388 9.16E-70 T 31-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 DFR85_09790 f3a1accc742e862fbf1849df9f98af01 391 Gene3D G3DSA:3.65.10.10 183 391 1.2E-46 T 31-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 DFR85_09790 f3a1accc742e862fbf1849df9f98af01 391 PIRSF PIRSF000505 1 391 2.6E-84 T 31-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 DFR85_09790 f3a1accc742e862fbf1849df9f98af01 391 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 37 381 2.3E-53 T 31-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 DFR85_09790 f3a1accc742e862fbf1849df9f98af01 391 Gene3D G3DSA:3.65.10.10 19 182 4.8E-24 T 31-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 DFR85_08870 d4959d02f9bb7644814bd44089fa8f53 421 SUPERFAMILY SSF56042 207 358 6.88E-19 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily DFR85_08870 d4959d02f9bb7644814bd44089fa8f53 421 Pfam PF02769 AIR synthase related protein, C-terminal domain 213 353 6.3E-9 T 31-10-2018 IPR010918 PurM-like, C-terminal domain DFR85_08870 d4959d02f9bb7644814bd44089fa8f53 421 Gene3D G3DSA:3.30.1330.10 50 205 3.1E-14 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily DFR85_08870 d4959d02f9bb7644814bd44089fa8f53 421 SUPERFAMILY SSF55326 91 189 1.02E-15 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily DFR85_08870 d4959d02f9bb7644814bd44089fa8f53 421 Gene3D G3DSA:3.90.650.10 209 375 3.2E-17 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily DFR85_08870 d4959d02f9bb7644814bd44089fa8f53 421 Pfam PF00586 AIR synthase related protein, N-terminal domain 93 181 3.5E-7 T 31-10-2018 IPR016188 PurM-like, N-terminal domain DFR85_06380 cf7df0b6f8f029d21d013b9124d2f501 378 SUPERFAMILY SSF53383 14 375 9.21E-80 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase DFR85_06380 cf7df0b6f8f029d21d013b9124d2f501 378 Pfam PF00155 Aminotransferase class I and II 25 367 5.2E-25 T 31-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 DFR85_06380 cf7df0b6f8f029d21d013b9124d2f501 378 Gene3D G3DSA:3.90.1150.10 17 375 4.8E-91 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 DFR85_06380 cf7df0b6f8f029d21d013b9124d2f501 378 Gene3D G3DSA:3.40.640.10 60 275 4.8E-91 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR85_06560 b845c8691578dc29babc8e2f6df02030 283 TIGRFAM TIGR02144 LysX_arch: lysine biosynthesis enzyme LysX 3 283 4.5E-108 T 31-10-2018 IPR011870 Lysine biosynthesis enzyme LysX GO:0003824|GO:0005524|GO:0009085 DFR85_06560 b845c8691578dc29babc8e2f6df02030 283 Gene3D G3DSA:3.30.1490.20 104 172 6.5E-24 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 DFR85_06560 b845c8691578dc29babc8e2f6df02030 283 Gene3D G3DSA:3.40.50.20 2 102 7.3E-23 T 31-10-2018 DFR85_06560 b845c8691578dc29babc8e2f6df02030 283 SUPERFAMILY SSF52440 3 88 1.18E-20 T 31-10-2018 IPR016185 Pre-ATP-grasp domain superfamily DFR85_06560 b845c8691578dc29babc8e2f6df02030 283 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 3 277 1.7E-76 T 31-10-2018 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 Reactome: R-HSA-70614 DFR85_06560 b845c8691578dc29babc8e2f6df02030 283 Gene3D G3DSA:3.30.470.80 173 282 2.2E-27 T 31-10-2018 DFR85_06560 b845c8691578dc29babc8e2f6df02030 283 Pfam PF08443 RimK-like ATP-grasp domain 87 276 6.3E-35 T 31-10-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 DFR85_06560 b845c8691578dc29babc8e2f6df02030 283 SUPERFAMILY SSF56059 78 279 2.65E-46 T 31-10-2018 DFR85_04225 fcd4ce54508ddae7475ba0a3efeb2bea 134 Pfam PF05433 Glycine zipper 2TM domain 53 94 2.4E-11 T 31-10-2018 IPR008816 Glycine zipper 2TM domain GO:0019867 DFR85_06710 b9de6a461332dde74a2c47e0086fcc98 408 Gene3D G3DSA:3.40.50.720 159 299 6.2E-25 T 31-10-2018 DFR85_06710 b9de6a461332dde74a2c47e0086fcc98 408 PIRSF PIRSF000445 10 407 2.1E-90 T 31-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 DFR85_06710 b9de6a461332dde74a2c47e0086fcc98 408 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 300 394 2.8E-16 T 31-10-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 DFR85_06710 b9de6a461332dde74a2c47e0086fcc98 408 Gene3D G3DSA:3.30.460.30 14 158 7.1E-33 T 31-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 DFR85_06710 b9de6a461332dde74a2c47e0086fcc98 408 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 46 395 4.2E-64 T 31-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 DFR85_06710 b9de6a461332dde74a2c47e0086fcc98 408 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 171 254 3.5E-17 T 31-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase DFR85_06710 b9de6a461332dde74a2c47e0086fcc98 408 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 99 122 - T 31-10-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 DFR85_06710 b9de6a461332dde74a2c47e0086fcc98 408 SUPERFAMILY SSF51735 160 271 7.1E-21 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_06710 b9de6a461332dde74a2c47e0086fcc98 408 SUPERFAMILY SSF69742 12 158 1.02E-30 T 31-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 DFR85_06710 b9de6a461332dde74a2c47e0086fcc98 408 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 11 393 20.512 T 31-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 DFR85_06710 b9de6a461332dde74a2c47e0086fcc98 408 SUPERFAMILY SSF69075 300 396 6.8E-20 T 31-10-2018 IPR036453 Glutamyl tRNA-reductase dimerization domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 DFR85_06710 b9de6a461332dde74a2c47e0086fcc98 408 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 18 156 8.2E-32 T 31-10-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 DFR85_15320 0bec03c347c53f5aa5106e371b200d7d 598 SUPERFAMILY SSF54897 32 193 6.63E-20 T 31-10-2018 DFR85_15320 0bec03c347c53f5aa5106e371b200d7d 598 Gene3D G3DSA:3.40.50.200 218 592 5.8E-53 T 31-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 DFR85_15320 0bec03c347c53f5aa5106e371b200d7d 598 Pfam PF09286 Pro-kumamolisin, activation domain 45 192 1.7E-22 T 31-10-2018 IPR015366 Peptidase S53, activation domain GO:0008236 Reactome: R-HSA-381038 DFR85_15320 0bec03c347c53f5aa5106e371b200d7d 598 SMART SM00944 42 193 2.6E-29 T 31-10-2018 IPR015366 Peptidase S53, activation domain GO:0008236 Reactome: R-HSA-381038 DFR85_15320 0bec03c347c53f5aa5106e371b200d7d 598 SUPERFAMILY SSF52743 228 592 3.67E-37 T 31-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 DFR85_03580 19af6e2221178459b3dc384fb2670824 266 Gene3D G3DSA:3.40.50.11590 112 227 2.0E-10 T 31-10-2018 DFR85_03580 19af6e2221178459b3dc384fb2670824 266 SUPERFAMILY SSF159713 18 254 6.67E-36 T 31-10-2018 DFR85_03580 19af6e2221178459b3dc384fb2670824 266 Gene3D G3DSA:3.30.390.100 28 232 2.0E-10 T 31-10-2018 DFR85_03580 19af6e2221178459b3dc384fb2670824 266 Pfam PF13938 Putative heavy-metal chelation 27 96 6.0E-9 T 31-10-2018 IPR025251 Domain of unknown function DUF4213 DFR85_03580 19af6e2221178459b3dc384fb2670824 266 Pfam PF04016 Putative heavy-metal chelation 112 254 2.9E-22 T 31-10-2018 IPR007161 Putative heavy-metal chelation domain DFR85_04175 2ba45517e8b36e251786adfd46bcd3f7 953 SMART SM00872 466 538 8.1E-22 T 31-10-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 DFR85_04175 2ba45517e8b36e251786adfd46bcd3f7 953 Gene3D G3DSA:3.20.110.10 208 463 1.9E-53 T 31-10-2018 IPR027291 Glycoside hydrolase 38, N-terminal domain superfamily DFR85_04175 2ba45517e8b36e251786adfd46bcd3f7 953 SUPERFAMILY SSF88688 465 566 2.55E-19 T 31-10-2018 IPR028995 Glycoside hydrolase families 57/38, central domain superfamily DFR85_04175 2ba45517e8b36e251786adfd46bcd3f7 953 Gene3D G3DSA:1.20.1270.50 469 559 2.7E-18 T 31-10-2018 IPR037094 Glycoside hydrolase family 38, central domain superfamily GO:0004559|GO:0006013 DFR85_04175 2ba45517e8b36e251786adfd46bcd3f7 953 SUPERFAMILY SSF88713 212 441 2.71E-60 T 31-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 DFR85_04175 2ba45517e8b36e251786adfd46bcd3f7 953 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 213 453 2.2E-68 T 31-10-2018 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0006013 DFR85_04175 2ba45517e8b36e251786adfd46bcd3f7 953 Pfam PF09261 Alpha mannosidase middle domain 466 537 9.5E-20 T 31-10-2018 IPR015341 Glycoside hydrolase family 38, central domain GO:0004559|GO:0006013 DFR85_04175 2ba45517e8b36e251786adfd46bcd3f7 953 Gene3D G3DSA:2.70.98.30 615 856 2.2E-23 T 31-10-2018 DFR85_04175 2ba45517e8b36e251786adfd46bcd3f7 953 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 563 951 2.0E-79 T 31-10-2018 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0004559|GO:0006013 DFR85_04175 2ba45517e8b36e251786adfd46bcd3f7 953 SUPERFAMILY SSF74650 557 952 1.1E-83 T 31-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 DFR85_10660 2265810cb303cce082ddc8b44be0d5b5 351 Gene3D G3DSA:3.40.50.10330 70 176 3.7E-6 T 31-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 DFR85_10660 2265810cb303cce082ddc8b44be0d5b5 351 PIRSF PIRSF016907 1 349 5.0E-128 T 31-10-2018 IPR011386 Putative ATP-NAD kinase DFR85_10660 2265810cb303cce082ddc8b44be0d5b5 351 SUPERFAMILY SSF111331 79 155 1.28E-6 T 31-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily DFR85_10660 2265810cb303cce082ddc8b44be0d5b5 351 Pfam PF01513 ATP-NAD kinase 2 346 1.5E-65 T 31-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 DFR85_10990 01a96b1bcac74b742e98c79514a7d1a7 90 Pfam PF12760 Transposase zinc-ribbon domain 63 86 7.7E-6 T 31-10-2018 IPR024442 Transposase, zinc-ribbon DFR85_10990 01a96b1bcac74b742e98c79514a7d1a7 90 Pfam PF02150 RNA polymerases M/15 Kd subunit 1 26 6.3E-8 T 31-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 DFR85_10990 01a96b1bcac74b742e98c79514a7d1a7 90 SMART SM00661 2 49 3.6E-12 T 31-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 DFR85_02000 d39cdfbf5246c21cea2fe36ae8fe22b0 52 SUPERFAMILY SSF47240 1 43 2.05E-10 T 31-10-2018 IPR009078 Ferritin-like superfamily DFR85_02000 d39cdfbf5246c21cea2fe36ae8fe22b0 52 Gene3D G3DSA:1.10.620.20 1 49 4.3E-12 T 31-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 DFR85_02000 d39cdfbf5246c21cea2fe36ae8fe22b0 52 Pfam PF04945 YHS domain 1 45 1.3E-21 T 31-10-2018 IPR007029 YHS domain DFR85_02000 d39cdfbf5246c21cea2fe36ae8fe22b0 52 SMART SM00746 3 40 4.1E-10 T 31-10-2018 IPR011017 TRASH domain DFR85_01230 0e3e86d9ce30ce71766d2f5ccac7955b 501 Pfam PF01256 Carbohydrate kinase 234 482 1.1E-50 T 31-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 DFR85_01230 0e3e86d9ce30ce71766d2f5ccac7955b 501 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 3 203 22.712 T 31-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 DFR85_01230 0e3e86d9ce30ce71766d2f5ccac7955b 501 Gene3D G3DSA:3.40.50.10260 2 207 6.0E-56 T 31-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 DFR85_01230 0e3e86d9ce30ce71766d2f5ccac7955b 501 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 211 489 23.114 T 31-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 DFR85_01230 0e3e86d9ce30ce71766d2f5ccac7955b 501 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 425 435 - T 31-10-2018 IPR017953 Carbohydrate kinase, predicted, conserved site DFR85_01230 0e3e86d9ce30ce71766d2f5ccac7955b 501 Gene3D G3DSA:3.40.1190.20 214 495 1.2E-79 T 31-10-2018 IPR029056 Ribokinase-like DFR85_01230 0e3e86d9ce30ce71766d2f5ccac7955b 501 SUPERFAMILY SSF53613 212 486 1.57E-67 T 31-10-2018 IPR029056 Ribokinase-like DFR85_01230 0e3e86d9ce30ce71766d2f5ccac7955b 501 PIRSF PIRSF017184 1 491 1.2E-103 T 31-10-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 DFR85_01230 0e3e86d9ce30ce71766d2f5ccac7955b 501 Pfam PF03853 YjeF-related protein N-terminus 24 187 4.6E-41 T 31-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 DFR85_01230 0e3e86d9ce30ce71766d2f5ccac7955b 501 SUPERFAMILY SSF64153 2 230 4.19E-56 T 31-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 DFR85_01230 0e3e86d9ce30ce71766d2f5ccac7955b 501 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 2 204 1.5E-55 T 31-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 DFR85_01230 0e3e86d9ce30ce71766d2f5ccac7955b 501 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 209 485 5.0E-72 T 31-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 DFR85_00960 e4c1cbd630895e5c1c9af471b3441bb9 337 Pfam PF04055 Radical SAM superfamily 38 183 1.3E-17 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR85_00960 e4c1cbd630895e5c1c9af471b3441bb9 337 Pfam PF11946 Domain of unknown function (DUF3463) 192 326 2.7E-28 T 31-10-2018 IPR022563 Domain of unknown function DUF3463 DFR85_00960 e4c1cbd630895e5c1c9af471b3441bb9 337 SUPERFAMILY SSF102114 30 303 1.44E-48 T 31-10-2018 DFR85_00960 e4c1cbd630895e5c1c9af471b3441bb9 337 PIRSF PIRSF037420 15 224 4.3E-37 T 31-10-2018 IPR017200 Coenzyme PQQ synthesis protein E DFR85_00960 e4c1cbd630895e5c1c9af471b3441bb9 337 PIRSF PIRSF037420 255 307 42.0 T 31-10-2018 IPR017200 Coenzyme PQQ synthesis protein E DFR85_00960 e4c1cbd630895e5c1c9af471b3441bb9 337 Gene3D G3DSA:3.20.20.70 34 300 1.9E-44 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_00960 e4c1cbd630895e5c1c9af471b3441bb9 337 TIGRFAM TIGR03961 rSAM_PTO1314: archaeal radical SAM protein, PTO1314 family 9 335 1.5E-168 T 31-10-2018 IPR023863 Archaeal radical SAM protein, PTO1314 family DFR85_00960 e4c1cbd630895e5c1c9af471b3441bb9 337 Pfam PF13353 4Fe-4S single cluster domain 36 132 1.6E-7 T 31-10-2018 DFR85_08550 ae4cea0b0ada79fca567d7650a502344 1144 Pfam PF02514 CobN/Magnesium Chelatase 103 1126 2.6E-297 T 31-10-2018 IPR003672 CobN/magnesium chelatase GO:0009058 DFR85_02530 27cd3864f219636c61e060ee2054d868 209 TIGRFAM TIGR00101 ureG: urease accessory protein UreG 2 195 1.2E-69 T 31-10-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 DFR85_02530 27cd3864f219636c61e060ee2054d868 209 Gene3D G3DSA:3.40.50.300 1 203 6.5E-47 T 31-10-2018 DFR85_02530 27cd3864f219636c61e060ee2054d868 209 PIRSF PIRSF005624 1 206 5.3E-50 T 31-10-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 DFR85_02530 27cd3864f219636c61e060ee2054d868 209 SUPERFAMILY SSF52540 2 198 5.92E-35 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_02530 27cd3864f219636c61e060ee2054d868 209 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 4 177 6.2E-29 T 31-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain DFR85_02265 986b8af2f4f41684325ae280821ff925 493 SMART SM00228 394 460 3.1E-4 T 31-10-2018 IPR001478 PDZ domain GO:0005515 DFR85_02265 986b8af2f4f41684325ae280821ff925 493 Gene3D G3DSA:1.10.390.60 146 371 2.8E-49 T 31-10-2018 DFR85_02265 986b8af2f4f41684325ae280821ff925 493 Pfam PF05299 M61 glycyl aminopeptidase 210 320 3.2E-31 T 31-10-2018 IPR007963 Peptidase M61, catalytic domain DFR85_02265 986b8af2f4f41684325ae280821ff925 493 Gene3D G3DSA:2.60.40.3650 11 137 1.2E-11 T 31-10-2018 DFR85_02265 986b8af2f4f41684325ae280821ff925 493 SUPERFAMILY SSF50156 376 460 5.13E-10 T 31-10-2018 IPR036034 PDZ superfamily GO:0005515 DFR85_02265 986b8af2f4f41684325ae280821ff925 493 PIRSF PIRSF016493 11 478 1.6E-89 T 31-10-2018 IPR024191 Peptidase M61 DFR85_02265 986b8af2f4f41684325ae280821ff925 493 Gene3D G3DSA:2.30.42.10 384 447 3.0E-8 T 31-10-2018 DFR85_00490 2e5f629abb87a673139b57032753c2d9 280 PIRSF PIRSF032817 2 278 8.2E-106 T 31-10-2018 IPR017008 Uncharacterised conserved protein UCP032817 DFR85_15260 160fcd20827f131e0a521e7e2424d1b0 561 SUPERFAMILY SSF50022 9 103 1.19E-21 T 31-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 DFR85_15260 160fcd20827f131e0a521e7e2424d1b0 561 Pfam PF00355 Rieske [2Fe-2S] domain 11 77 7.7E-11 T 31-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DFR85_15260 160fcd20827f131e0a521e7e2424d1b0 561 Gene3D G3DSA:2.102.10.10 6 102 7.9E-21 T 31-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 DFR85_04925 0fe228648bd740549dda856506328770 186 Pfam PF05050 Methyltransferase FkbM domain 2 156 1.0E-15 T 31-10-2018 IPR006342 Methyltransferase FkbM DFR85_04925 0fe228648bd740549dda856506328770 186 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 1 146 8.7E-32 T 31-10-2018 IPR006342 Methyltransferase FkbM DFR85_04925 0fe228648bd740549dda856506328770 186 SUPERFAMILY SSF53335 1 158 5.63E-30 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR85_04925 0fe228648bd740549dda856506328770 186 Gene3D G3DSA:3.40.50.150 1 167 5.4E-24 T 31-10-2018 DFR85_04520 9aec1973f7b6fb64a32de77e21f2950b 368 Pfam PF09336 Vps4 C terminal oligomerisation domain 332 366 9.9E-7 T 31-10-2018 IPR015415 Vps4 oligomerisation, C-terminal DFR85_04520 9aec1973f7b6fb64a32de77e21f2950b 368 Gene3D G3DSA:3.40.50.300 92 363 3.8E-83 T 31-10-2018 DFR85_04520 9aec1973f7b6fb64a32de77e21f2950b 368 Gene3D G3DSA:1.10.8.60 262 346 3.8E-83 T 31-10-2018 DFR85_04520 9aec1973f7b6fb64a32de77e21f2950b 368 SMART SM00382 129 263 7.0E-16 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_04520 9aec1973f7b6fb64a32de77e21f2950b 368 SUPERFAMILY SSF52540 95 365 7.96E-57 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_04520 9aec1973f7b6fb64a32de77e21f2950b 368 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 133 261 2.2E-35 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 DFR85_02905 b3ce8511cf0f16d655f53dc063609477 122 SMART SM00926 1 46 1.7E-4 T 31-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_02905 b3ce8511cf0f16d655f53dc063609477 122 Gene3D G3DSA:3.40.50.740 43 122 5.7E-10 T 31-10-2018 DFR85_02905 b3ce8511cf0f16d655f53dc063609477 122 SUPERFAMILY SSF53706 2 115 7.85E-22 T 31-10-2018 DFR85_02905 b3ce8511cf0f16d655f53dc063609477 122 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 2 44 3.7E-7 T 31-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_02905 b3ce8511cf0f16d655f53dc063609477 122 Gene3D G3DSA:2.20.25.90 1 42 2.7E-6 T 31-10-2018 DFR85_15605 f0fd4ba2edce0eaa73875cbdf3a9f1fc 401 Pfam PF07282 Putative transposase DNA-binding domain 303 372 3.2E-24 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR85_15605 f0fd4ba2edce0eaa73875cbdf3a9f1fc 401 Pfam PF01385 Probable transposase 181 286 7.6E-19 T 31-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 DFR85_15605 f0fd4ba2edce0eaa73875cbdf3a9f1fc 401 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 255 330 9.4E-16 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR85_06580 a212ae382fffeef8d27d0d7bc0ae6462 349 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 145 161 - T 31-10-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 DFR85_06580 a212ae382fffeef8d27d0d7bc0ae6462 349 SMART SM00859 3 142 2.1E-59 T 31-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 DFR85_06580 a212ae382fffeef8d27d0d7bc0ae6462 349 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 2 348 9.8E-130 T 31-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 DFR85_06580 a212ae382fffeef8d27d0d7bc0ae6462 349 Gene3D G3DSA:3.40.50.720 3 331 9.1E-111 T 31-10-2018 DFR85_06580 a212ae382fffeef8d27d0d7bc0ae6462 349 Gene3D G3DSA:3.30.360.10 148 316 9.1E-111 T 31-10-2018 DFR85_06580 a212ae382fffeef8d27d0d7bc0ae6462 349 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 179 319 1.7E-8 T 31-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 DFR85_06580 a212ae382fffeef8d27d0d7bc0ae6462 349 SUPERFAMILY SSF55347 150 316 2.22E-40 T 31-10-2018 DFR85_06580 a212ae382fffeef8d27d0d7bc0ae6462 349 SUPERFAMILY SSF51735 1 163 1.95E-52 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_06580 a212ae382fffeef8d27d0d7bc0ae6462 349 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 3 142 3.7E-35 T 31-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 DFR85_06580 a212ae382fffeef8d27d0d7bc0ae6462 349 Hamap MF_02083 [LysW]-L-2-aminoadipate/[LysW]-L-glutamate phosphate reductase [lysY]. 2 348 52.384 T 31-10-2018 IPR037535 [LysW]-L-2-aminoadipate/[LysW]-L-glutamate phosphate reductase GO:0016620 DFR85_06580 a212ae382fffeef8d27d0d7bc0ae6462 349 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 2 342 39.879 T 31-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 DFR85_07895 dda4cd4754b253d1d0b8fc62408a7cf2 433 SUPERFAMILY SSF52317 208 349 2.06E-24 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like DFR85_07895 dda4cd4754b253d1d0b8fc62408a7cf2 433 Gene3D G3DSA:3.40.50.880 234 417 2.4E-9 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like DFR85_07895 dda4cd4754b253d1d0b8fc62408a7cf2 433 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 5 429 2.1E-126 T 31-10-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 DFR85_07895 dda4cd4754b253d1d0b8fc62408a7cf2 433 Hamap MF_00027 Hydrogenobyrinate a,c-diamide synthase [cobB]. 3 428 40.183 T 31-10-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 DFR85_07895 dda4cd4754b253d1d0b8fc62408a7cf2 433 SUPERFAMILY SSF52540 1 188 3.15E-34 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_07895 dda4cd4754b253d1d0b8fc62408a7cf2 433 Gene3D G3DSA:3.40.50.300 50 182 8.5E-15 T 31-10-2018 DFR85_07895 dda4cd4754b253d1d0b8fc62408a7cf2 433 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 242 425 6.4E-35 T 31-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 DFR85_07895 dda4cd4754b253d1d0b8fc62408a7cf2 433 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 184 1.7E-14 T 31-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain DFR85_06570 a50eb1d30e71d56bab6cc7425f8313f3 141 Pfam PF01037 Lrp/AsnC ligand binding domain 76 139 8.7E-12 T 31-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DFR85_06570 a50eb1d30e71d56bab6cc7425f8313f3 141 SUPERFAMILY SSF54909 64 139 9.12E-14 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel DFR85_06570 a50eb1d30e71d56bab6cc7425f8313f3 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 1.1E-7 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR85_06570 a50eb1d30e71d56bab6cc7425f8313f3 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 1.1E-7 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR85_06570 a50eb1d30e71d56bab6cc7425f8313f3 141 SUPERFAMILY SSF46785 4 57 3.54E-12 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_06570 a50eb1d30e71d56bab6cc7425f8313f3 141 Gene3D G3DSA:3.30.70.920 57 140 3.1E-15 T 31-10-2018 DFR85_06570 a50eb1d30e71d56bab6cc7425f8313f3 141 Gene3D G3DSA:1.10.10.10 1 56 1.2E-18 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_06570 a50eb1d30e71d56bab6cc7425f8313f3 141 SMART SM00344 5 109 2.3E-21 T 31-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 DFR85_06570 a50eb1d30e71d56bab6cc7425f8313f3 141 Pfam PF13412 Winged helix-turn-helix DNA-binding 6 52 2.7E-12 T 31-10-2018 DFR85_14605 8a2dd49e43c4edb9c8dcdf8a3ee09df2 315 Gene3D G3DSA:3.90.180.10 1 315 2.0E-70 T 31-10-2018 DFR85_14605 8a2dd49e43c4edb9c8dcdf8a3ee09df2 315 SMART SM00829 4 313 1.4E-4 T 31-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DFR85_14605 8a2dd49e43c4edb9c8dcdf8a3ee09df2 315 SUPERFAMILY SSF51735 124 284 1.18E-28 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_14605 8a2dd49e43c4edb9c8dcdf8a3ee09df2 315 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 119 1.4E-20 T 31-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DFR85_14605 8a2dd49e43c4edb9c8dcdf8a3ee09df2 315 SUPERFAMILY SSF50129 2 154 1.07E-35 T 31-10-2018 IPR011032 GroES-like superfamily DFR85_14605 8a2dd49e43c4edb9c8dcdf8a3ee09df2 315 Pfam PF00107 Zinc-binding dehydrogenase 161 278 7.5E-18 T 31-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DFR85_14265 09bebcb524f91ac13d94a5d3df0f6336 245 SUPERFAMILY SSF144083 180 242 5.36E-8 T 31-10-2018 DFR85_14265 09bebcb524f91ac13d94a5d3df0f6336 245 Gene3D G3DSA:1.20.58.340 168 245 3.5E-12 T 31-10-2018 DFR85_14265 09bebcb524f91ac13d94a5d3df0f6336 245 Pfam PF01544 CorA-like Mg2+ transporter protein 67 238 3.4E-14 T 31-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 DFR85_10120 1101d6ac07a92709c916ae4a14c1de41 153 Gene3D G3DSA:1.10.10.2700 1 151 4.2E-45 T 31-10-2018 IPR038111 Ribosomal protein S19e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_10120 1101d6ac07a92709c916ae4a14c1de41 153 SUPERFAMILY SSF46785 2 151 1.76E-42 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_10120 1101d6ac07a92709c916ae4a14c1de41 153 Pfam PF01090 Ribosomal protein S19e 3 138 4.6E-44 T 31-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_10120 1101d6ac07a92709c916ae4a14c1de41 153 SMART SM01413 3 140 1.4E-61 T 31-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_10120 1101d6ac07a92709c916ae4a14c1de41 153 ProDom PD003854 RIBOSOMAL 40S RIBONUCLEOPROTEIN S19 S19E 30S MULTIGENE FAMILY S19 SSU 3 119 4.0E-44 T 31-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_10120 1101d6ac07a92709c916ae4a14c1de41 153 Hamap MF_01474 30S ribosomal protein S19e [rps19e]. 1 149 29.917 T 31-10-2018 IPR027548 Ribosomal protein S19e, archaeal GO:0003735|GO:0005840|GO:0006412 DFR85_08490 a061f9ed3359245bdf078e8e528fae9b 468 SMART SM00840 353 413 4.0E-8 T 31-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 DFR85_08490 a061f9ed3359245bdf078e8e528fae9b 468 SUPERFAMILY SSF52374 12 309 1.61E-89 T 31-10-2018 DFR85_08490 a061f9ed3359245bdf078e8e528fae9b 468 Gene3D G3DSA:1.20.120.640 304 467 3.6E-23 T 31-10-2018 DFR85_08490 a061f9ed3359245bdf078e8e528fae9b 468 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 5 466 2.3E-146 T 31-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 DFR85_08490 a061f9ed3359245bdf078e8e528fae9b 468 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 1.5E-29 T 31-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 DFR85_08490 a061f9ed3359245bdf078e8e528fae9b 468 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 189 207 1.5E-29 T 31-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 DFR85_08490 a061f9ed3359245bdf078e8e528fae9b 468 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 220 241 1.5E-29 T 31-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 DFR85_08490 a061f9ed3359245bdf078e8e528fae9b 468 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 1.5E-29 T 31-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 DFR85_08490 a061f9ed3359245bdf078e8e528fae9b 468 SUPERFAMILY SSF47323 345 467 1.5E-23 T 31-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR85_08490 a061f9ed3359245bdf078e8e528fae9b 468 Gene3D G3DSA:3.40.50.620 2 303 3.8E-130 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR85_08490 a061f9ed3359245bdf078e8e528fae9b 468 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 18 311 1.8E-123 T 31-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 DFR85_08490 a061f9ed3359245bdf078e8e528fae9b 468 Pfam PF09190 DALR domain 353 411 3.9E-8 T 31-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 DFR85_08490 a061f9ed3359245bdf078e8e528fae9b 468 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 4 468 34.627 T 31-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 DFR85_07595 11f456cedbf8f24590eb50f084a07a01 268 Gene3D G3DSA:2.40.30.90 163 258 2.0E-24 T 31-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal DFR85_07595 11f456cedbf8f24590eb50f084a07a01 268 Pfam PF01887 S-adenosyl-l-methionine hydroxide adenosyltransferase 5 254 1.1E-74 T 31-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase DFR85_07595 11f456cedbf8f24590eb50f084a07a01 268 SUPERFAMILY SSF101852 169 257 6.41E-23 T 31-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal DFR85_07595 11f456cedbf8f24590eb50f084a07a01 268 PIRSF PIRSF006779 1 259 1.1E-93 T 31-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase DFR85_07595 11f456cedbf8f24590eb50f084a07a01 268 Gene3D G3DSA:3.40.50.10790 4 160 4.3E-55 T 31-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal DFR85_07595 11f456cedbf8f24590eb50f084a07a01 268 SUPERFAMILY SSF102522 3 163 1.44E-55 T 31-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal DFR85_02650 303ab42735a5f50463357b870569d8c2 322 Pfam PF00005 ABC transporter 22 186 2.0E-30 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR85_02650 303ab42735a5f50463357b870569d8c2 322 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DFR85_02650 303ab42735a5f50463357b870569d8c2 322 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 236 320 9.8E-27 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 DFR85_02650 303ab42735a5f50463357b870569d8c2 322 SMART SM00382 31 243 5.3E-18 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_02650 303ab42735a5f50463357b870569d8c2 322 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 237 301 1.0E-19 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 DFR85_02650 303ab42735a5f50463357b870569d8c2 322 SUPERFAMILY SSF52540 2 265 3.71E-66 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_02650 303ab42735a5f50463357b870569d8c2 322 Gene3D G3DSA:3.40.50.300 1 322 2.1E-99 T 31-10-2018 DFR85_00850 7a5ae4893b8e38d507f506a4f1d95eca 188 Gene3D G3DSA:3.90.550.10 2 176 2.4E-44 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_00850 7a5ae4893b8e38d507f506a4f1d95eca 188 Pfam PF12804 MobA-like NTP transferase domain 6 156 9.0E-29 T 31-10-2018 IPR025877 MobA-like NTP transferase DFR85_00850 7a5ae4893b8e38d507f506a4f1d95eca 188 SUPERFAMILY SSF53448 1 179 1.4E-23 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_12345 2fdb12d91cbab9f6b7a01c405db9f286 401 Pfam PF07282 Putative transposase DNA-binding domain 303 372 3.2E-24 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR85_12345 2fdb12d91cbab9f6b7a01c405db9f286 401 Pfam PF01385 Probable transposase 181 287 5.6E-20 T 31-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 DFR85_12345 2fdb12d91cbab9f6b7a01c405db9f286 401 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 255 330 1.3E-16 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR85_12375 2fdb12d91cbab9f6b7a01c405db9f286 401 Pfam PF07282 Putative transposase DNA-binding domain 303 372 3.2E-24 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR85_12375 2fdb12d91cbab9f6b7a01c405db9f286 401 Pfam PF01385 Probable transposase 181 287 5.6E-20 T 31-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 DFR85_12375 2fdb12d91cbab9f6b7a01c405db9f286 401 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 255 330 1.3E-16 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR85_04400 51b377a1506bb1d568211ea7483855de 341 Pfam PF00535 Glycosyl transferase family 2 5 138 2.4E-18 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 DFR85_04400 51b377a1506bb1d568211ea7483855de 341 SUPERFAMILY SSF53448 2 222 5.16E-29 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_04400 51b377a1506bb1d568211ea7483855de 341 Gene3D G3DSA:3.90.550.10 1 258 8.0E-25 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_04210 0a43719574ba39083f262ca4a906914f 235 Gene3D G3DSA:3.20.20.70 1 231 2.1E-50 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_04210 0a43719574ba39083f262ca4a906914f 235 SUPERFAMILY SSF51445 1 231 2.74E-44 T 31-10-2018 IPR017853 Glycoside hydrolase superfamily DFR85_04210 0a43719574ba39083f262ca4a906914f 235 Pfam PF05913 Bacterial protein of unknown function (DUF871) 4 232 2.0E-47 T 31-10-2018 IPR008589 Protein of unknown function DUF871, prokaryotic DFR85_02235 466cfd56b54734fb99c85b9e1f546afe 250 SMART SM00382 5 185 2.5E-14 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_02235 466cfd56b54734fb99c85b9e1f546afe 250 Gene3D G3DSA:3.40.50.300 1 212 1.6E-58 T 31-10-2018 DFR85_02235 466cfd56b54734fb99c85b9e1f546afe 250 SUPERFAMILY SSF52540 2 200 4.1E-56 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_02235 466cfd56b54734fb99c85b9e1f546afe 250 Pfam PF00005 ABC transporter 1 137 9.8E-34 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR85_02235 466cfd56b54734fb99c85b9e1f546afe 250 ProSitePatterns PS00211 ABC transporters family signature. 110 124 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DFR85_13225 bcbb5c7cddb6525305583e80c1bf5d41 419 Pfam PF09455 CRISPR-associated (Cas) DxTHG family 3 389 5.4E-23 T 31-10-2018 IPR019016 CRISPR-associated DxTHG protein DFR85_13225 bcbb5c7cddb6525305583e80c1bf5d41 419 SUPERFAMILY SSF160980 1 416 9.68E-77 T 31-10-2018 DFR85_13225 bcbb5c7cddb6525305583e80c1bf5d41 419 TIGRFAM TIGR02549 CRISPR_DxTHG: CRISPR-associated DxTHG motif protein 123 143 3.0E-11 T 31-10-2018 IPR013383 CRISPR-associated protein DxTHG, conserved site DFR85_13225 bcbb5c7cddb6525305583e80c1bf5d41 419 TIGRFAM TIGR01897 cas_MJ1666: CRISPR-associated protein, MJ1666 family 1 414 3.9E-93 T 31-10-2018 IPR010171 CRISPR-associated protein, MJ1666 DFR85_13225 bcbb5c7cddb6525305583e80c1bf5d41 419 Gene3D G3DSA:1.10.3740.10 207 414 2.9E-103 T 31-10-2018 IPR027419 CRISPR-associated protein Csx1, C-terminal DFR85_13225 bcbb5c7cddb6525305583e80c1bf5d41 419 Gene3D G3DSA:3.40.50.10640 3 277 2.9E-103 T 31-10-2018 DFR85_02435 5097db72750ac4c91e05e1f8745c05c3 287 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 54 192 9.0E-22 T 31-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 DFR85_02435 5097db72750ac4c91e05e1f8745c05c3 287 Gene3D G3DSA:3.40.50.970 79 287 8.9E-72 T 31-10-2018 DFR85_02435 5097db72750ac4c91e05e1f8745c05c3 287 SUPERFAMILY SSF52518 3 283 9.7E-78 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR85_09895 9906516dbd4a6a2cfbde9db079ba6eff 707 Pfam PF04898 Glutamate synthase central domain 425 483 8.8E-8 T 31-10-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 DFR85_09895 9906516dbd4a6a2cfbde9db079ba6eff 707 Pfam PF01645 Conserved region in glutamate synthase 42 377 6.8E-92 T 31-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 DFR85_09895 9906516dbd4a6a2cfbde9db079ba6eff 707 SUPERFAMILY SSF51395 423 681 5.04E-23 T 31-10-2018 DFR85_09895 9906516dbd4a6a2cfbde9db079ba6eff 707 Gene3D G3DSA:3.20.20.70 15 410 3.1E-104 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_09895 9906516dbd4a6a2cfbde9db079ba6eff 707 Gene3D G3DSA:3.20.20.70 418 699 3.8E-9 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_09895 9906516dbd4a6a2cfbde9db079ba6eff 707 SUPERFAMILY SSF51395 48 394 1.95E-93 T 31-10-2018 DFR85_01435 d0333db9a06239325bc81a8db20ad095 312 Gene3D G3DSA:3.40.50.10800 9 290 4.8E-105 T 31-10-2018 DFR85_01435 d0333db9a06239325bc81a8db20ad095 312 Gene3D G3DSA:3.40.50.10800 174 265 4.8E-105 T 31-10-2018 DFR85_01435 d0333db9a06239325bc81a8db20ad095 312 SUPERFAMILY SSF142754 6 308 1.31E-100 T 31-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 DFR85_01435 d0333db9a06239325bc81a8db20ad095 312 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 5 309 5.3E-98 T 31-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 DFR85_01435 d0333db9a06239325bc81a8db20ad095 312 Gene3D G3DSA:3.40.50.10800 89 307 4.8E-105 T 31-10-2018 DFR85_01435 d0333db9a06239325bc81a8db20ad095 312 Pfam PF02445 Quinolinate synthetase A protein 10 307 1.8E-102 T 31-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 DFR85_01435 d0333db9a06239325bc81a8db20ad095 312 Hamap MF_00568 Quinolinate synthase A [nadA]. 5 309 43.37 T 31-10-2018 IPR023066 Quinolinate synthase A, type 2 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 DFR85_08255 c51b7a3628c5d93ebeec8d7aed5afbeb 130 ProSitePatterns PS00028 Zinc finger C2H2 type domain signature. 104 125 - T 31-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 DFR85_08255 c51b7a3628c5d93ebeec8d7aed5afbeb 130 SUPERFAMILY SSF57667 74 111 1.34E-6 T 31-10-2018 IPR036236 Zinc finger C2H2 superfamily DFR85_08255 c51b7a3628c5d93ebeec8d7aed5afbeb 130 Gene3D G3DSA:3.30.160.60 76 126 1.2E-10 T 31-10-2018 DFR85_08255 c51b7a3628c5d93ebeec8d7aed5afbeb 130 ProSitePatterns PS00028 Zinc finger C2H2 type domain signature. 78 100 - T 31-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 DFR85_08255 c51b7a3628c5d93ebeec8d7aed5afbeb 130 Pfam PF00096 Zinc finger, C2H2 type 103 125 0.0024 T 31-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 DFR85_08255 c51b7a3628c5d93ebeec8d7aed5afbeb 130 Pfam PF00096 Zinc finger, C2H2 type 76 100 0.0013 T 31-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 DFR85_08255 c51b7a3628c5d93ebeec8d7aed5afbeb 130 SMART SM00355 76 100 0.069 T 31-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 DFR85_08255 c51b7a3628c5d93ebeec8d7aed5afbeb 130 SMART SM00355 102 125 0.67 T 31-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 DFR85_13825 d42879d741d52d890b777dda1a150d57 345 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 200 341 3.7E-32 T 31-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DFR85_13825 d42879d741d52d890b777dda1a150d57 345 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 106 193 3.3E-19 T 31-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 DFR85_13825 d42879d741d52d890b777dda1a150d57 345 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 3 90 5.6E-11 T 31-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 DFR85_13825 d42879d741d52d890b777dda1a150d57 345 SUPERFAMILY SSF56645 4 195 1.15E-38 T 31-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 DFR85_13825 d42879d741d52d890b777dda1a150d57 345 SUPERFAMILY SSF47203 199 342 2.26E-33 T 31-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 DFR85_13825 d42879d741d52d890b777dda1a150d57 345 Gene3D G3DSA:2.40.110.10 105 197 5.0E-22 T 31-10-2018 DFR85_13825 d42879d741d52d890b777dda1a150d57 345 Gene3D G3DSA:1.20.140.10 200 344 5.3E-32 T 31-10-2018 DFR85_13825 d42879d741d52d890b777dda1a150d57 345 Gene3D G3DSA:1.10.540.10 2 97 3.2E-14 T 31-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 DFR85_15685 97325fefb67ffc9876eccdf701973a02 49 Pfam PF12156 Putative metal-binding domain of cation transport ATPase 11 45 4.0E-7 T 31-10-2018 IPR021993 Putative metal-binding domain of cation transport ATPase DFR85_15685 97325fefb67ffc9876eccdf701973a02 49 SMART SM00746 12 49 1.3E-6 T 31-10-2018 IPR011017 TRASH domain DFR85_07210 ce7f262ae8f839caee1e1981b8c5c034 214 SUPERFAMILY SSF54189 3 192 2.83E-70 T 31-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_07210 ce7f262ae8f839caee1e1981b8c5c034 214 Pfam PF00827 Ribosomal L15 4 188 1.9E-70 T 31-10-2018 IPR000439 Ribosomal protein L15e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07210 ce7f262ae8f839caee1e1981b8c5c034 214 SMART SM01384 4 190 5.5E-97 T 31-10-2018 IPR000439 Ribosomal protein L15e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07210 ce7f262ae8f839caee1e1981b8c5c034 214 Gene3D G3DSA:3.40.1120.10 2 193 2.2E-70 T 31-10-2018 IPR024794 Ribosomal protein L15e core domain superfamily GO:0003735|GO:0005840 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_04205 f242e8b3ba00bba4f485e9170d7d9987 584 Gene3D G3DSA:3.40.50.10490 232 438 1.3E-52 T 31-10-2018 DFR85_04205 f242e8b3ba00bba4f485e9170d7d9987 584 Pfam PF13522 Glutamine amidotransferase domain 61 166 9.9E-16 T 31-10-2018 DFR85_04205 f242e8b3ba00bba4f485e9170d7d9987 584 Gene3D G3DSA:3.60.20.10 3 231 2.0E-49 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR85_04205 f242e8b3ba00bba4f485e9170d7d9987 584 SUPERFAMILY SSF56235 3 223 3.77E-44 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR85_04205 f242e8b3ba00bba4f485e9170d7d9987 584 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 3 582 5.1E-140 T 31-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 DFR85_04205 f242e8b3ba00bba4f485e9170d7d9987 584 SUPERFAMILY SSF53697 237 582 7.7E-76 T 31-10-2018 DFR85_04205 f242e8b3ba00bba4f485e9170d7d9987 584 Gene3D G3DSA:3.40.50.10490 439 584 3.6E-34 T 31-10-2018 DFR85_04205 f242e8b3ba00bba4f485e9170d7d9987 584 Pfam PF01380 SIS domain 450 533 4.9E-9 T 31-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 DFR85_04205 f242e8b3ba00bba4f485e9170d7d9987 584 Pfam PF01380 SIS domain 276 400 1.8E-24 T 31-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 DFR85_03680 9221b3b09b94b969f61638878f48cc07 335 SUPERFAMILY SSF53448 5 233 1.03E-27 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_03680 9221b3b09b94b969f61638878f48cc07 335 Gene3D G3DSA:3.90.550.10 1 270 7.9E-21 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_03680 9221b3b09b94b969f61638878f48cc07 335 Pfam PF00535 Glycosyl transferase family 2 6 124 4.8E-15 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 DFR85_07020 6e8d9c5ad3672d96b281a0a5e353afc1 134 SMART SM01393 23 133 4.5E-37 T 31-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07020 6e8d9c5ad3672d96b281a0a5e353afc1 134 Pfam PF01655 Ribosomal protein L32 23 133 9.9E-31 T 31-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07020 6e8d9c5ad3672d96b281a0a5e353afc1 134 ProDom PD003823 RIBOSOMAL L32 RIBONUCLEOPROTEIN 60S L32E 50S L32 STRAIN CHROMOSOME DIRECT 15 133 4.0E-26 T 31-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07020 6e8d9c5ad3672d96b281a0a5e353afc1 134 SUPERFAMILY SSF52042 13 133 2.35E-35 T 31-10-2018 IPR036351 Ribosomal protein L32e superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07635 368918a1840ce850433734519087d757 310 Gene3D G3DSA:1.10.10.10 10 44 2.9E-5 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_07635 368918a1840ce850433734519087d757 310 Gene3D G3DSA:3.30.70.3460 55 162 1.0E-10 T 31-10-2018 DFR85_07635 368918a1840ce850433734519087d757 310 Gene3D G3DSA:3.30.70.3460 186 307 1.1E-13 T 31-10-2018 DFR85_03940 c2cf1ec6cf5af784297fcfce5f062ed4 114 Gene3D G3DSA:3.30.460.10 1 110 2.2E-28 T 31-10-2018 DFR85_03940 c2cf1ec6cf5af784297fcfce5f062ed4 114 SUPERFAMILY SSF81301 21 101 3.27E-15 T 31-10-2018 DFR85_03940 c2cf1ec6cf5af784297fcfce5f062ed4 114 Pfam PF01909 Nucleotidyltransferase domain 18 84 1.2E-9 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 DFR85_12145 3524524050adc8be047f0479903f280b 82 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 3 81 2.2E-13 T 31-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 DFR85_12145 3524524050adc8be047f0479903f280b 82 Gene3D G3DSA:3.30.70.240 1 68 7.9E-24 T 31-10-2018 DFR85_12145 3524524050adc8be047f0479903f280b 82 SUPERFAMILY SSF143430 2 79 6.28E-16 T 31-10-2018 DFR85_12145 3524524050adc8be047f0479903f280b 82 Pfam PF09827 CRISPR associated protein Cas2 3 74 2.4E-15 T 31-10-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 DFR85_12145 3524524050adc8be047f0479903f280b 82 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 2 82 14.19 T 31-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 DFR85_02850 43ce9b7668faf7673c85b969d78e07ea 448 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 32 417 9.3E-12 T 31-10-2018 IPR001248 Purine-cytosine permease GO:0016020|GO:0022857|GO:0055085 DFR85_02850 43ce9b7668faf7673c85b969d78e07ea 448 Gene3D G3DSA:1.10.4160.10 27 439 7.8E-39 T 31-10-2018 IPR038271 Purine-cytosine permease superfamily DFR85_08220 d850379841737c9fe6b3cf312935c55b 143 Pfam PF04138 GtrA-like protein 6 142 9.2E-21 T 31-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 DFR85_14915 7dc8b0c221707caa44450d6414cd0e32 325 SUPERFAMILY SSF56176 24 190 3.83E-35 T 31-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 DFR85_14915 7dc8b0c221707caa44450d6414cd0e32 325 Gene3D G3DSA:3.30.465.40 5 206 2.0E-31 T 31-10-2018 DFR85_14915 7dc8b0c221707caa44450d6414cd0e32 325 Pfam PF01565 FAD binding domain 27 153 8.5E-24 T 31-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 DFR85_00310 d3f3dac8b3fcccf97bdb0cfb343a25af 560 Gene3D G3DSA:1.20.1250.20 288 485 1.3E-15 T 31-10-2018 DFR85_00310 d3f3dac8b3fcccf97bdb0cfb343a25af 560 Pfam PF07690 Major Facilitator Superfamily 12 424 2.7E-37 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_00310 d3f3dac8b3fcccf97bdb0cfb343a25af 560 SUPERFAMILY SSF103473 4 473 9.42E-47 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_00310 d3f3dac8b3fcccf97bdb0cfb343a25af 560 Gene3D G3DSA:1.20.1720.10 10 237 5.1E-32 T 31-10-2018 DFR85_11010 3f2caf4d58b0886fb3946253df5cf9aa 125 Gene3D G3DSA:3.40.50.1010 2 125 8.1E-31 T 31-10-2018 DFR85_11010 3f2caf4d58b0886fb3946253df5cf9aa 125 SUPERFAMILY SSF88723 5 123 8.97E-27 T 31-10-2018 IPR029060 PIN-like domain superfamily DFR85_12495 cd6dbaca420a265814f63ff63f2246fe 348 Pfam PF04909 Amidohydrolase 2 347 2.5E-31 T 31-10-2018 IPR006680 Amidohydrolase-related GO:0016787 DFR85_12495 cd6dbaca420a265814f63ff63f2246fe 348 SUPERFAMILY SSF51556 140 348 1.17E-19 T 31-10-2018 IPR032466 Metal-dependent hydrolase DFR85_12495 cd6dbaca420a265814f63ff63f2246fe 348 Gene3D G3DSA:3.20.20.140 1 348 4.6E-75 T 31-10-2018 DFR85_06030 4126641f3c7728d28dd173aab9cedd7b 154 Gene3D G3DSA:1.10.10.10 4 56 1.9E-22 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_06030 4126641f3c7728d28dd173aab9cedd7b 154 SUPERFAMILY SSF54909 66 148 2.41E-20 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel DFR85_06030 4126641f3c7728d28dd173aab9cedd7b 154 SMART SM00344 6 112 2.5E-45 T 31-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 DFR85_06030 4126641f3c7728d28dd173aab9cedd7b 154 Pfam PF13412 Winged helix-turn-helix DNA-binding 6 53 3.1E-17 T 31-10-2018 DFR85_06030 4126641f3c7728d28dd173aab9cedd7b 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 33 2.4E-15 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR85_06030 4126641f3c7728d28dd173aab9cedd7b 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 22 2.4E-15 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR85_06030 4126641f3c7728d28dd173aab9cedd7b 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 52 2.4E-15 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR85_06030 4126641f3c7728d28dd173aab9cedd7b 154 SUPERFAMILY SSF46785 4 65 6.74E-18 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_06030 4126641f3c7728d28dd173aab9cedd7b 154 Pfam PF01037 Lrp/AsnC ligand binding domain 72 142 2.9E-17 T 31-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DFR85_06030 4126641f3c7728d28dd173aab9cedd7b 154 Gene3D G3DSA:3.30.70.920 59 150 1.5E-24 T 31-10-2018 DFR85_00200 49201d73af34e7eb7b5ed6881c7e2a2c 1059 Gene3D G3DSA:2.40.40.20 914 1049 1.1E-34 T 31-10-2018 DFR85_00200 49201d73af34e7eb7b5ed6881c7e2a2c 1059 Gene3D G3DSA:3.30.200.200 17 695 1.1E-100 T 31-10-2018 DFR85_00200 49201d73af34e7eb7b5ed6881c7e2a2c 1059 SUPERFAMILY SSF50692 919 1039 1.2E-25 T 31-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily DFR85_00200 49201d73af34e7eb7b5ed6881c7e2a2c 1059 Gene3D G3DSA:3.40.50.740 161 725 1.1E-100 T 31-10-2018 DFR85_00200 49201d73af34e7eb7b5ed6881c7e2a2c 1059 Pfam PF01568 Molydopterin dinucleotide binding domain 948 1032 7.4E-16 T 31-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 DFR85_00200 49201d73af34e7eb7b5ed6881c7e2a2c 1059 SUPERFAMILY SSF53706 13 806 3.02E-69 T 31-10-2018 DFR85_00200 49201d73af34e7eb7b5ed6881c7e2a2c 1059 Gene3D G3DSA:3.40.228.10 252 498 1.1E-100 T 31-10-2018 DFR85_00200 49201d73af34e7eb7b5ed6881c7e2a2c 1059 Pfam PF00384 Molybdopterin oxidoreductase 160 441 5.9E-8 T 31-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_08035 91d7aa9bfe6922b311cf2a0c1ef3f7db 63 SMART SM01402 13 56 4.2E-19 T 31-10-2018 IPR002906 Ribosomal protein S27a GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 DFR85_08035 91d7aa9bfe6922b311cf2a0c1ef3f7db 63 Gene3D G3DSA:2.20.25.660 1 60 8.4E-11 T 31-10-2018 IPR038582 S27a-like superfamily Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 DFR85_08035 91d7aa9bfe6922b311cf2a0c1ef3f7db 63 Hamap MF_00777 30S ribosomal protein S27ae [rps27ae]. 13 59 17.309 T 31-10-2018 IPR022845 Ribosomal protein S27ae DFR85_08035 91d7aa9bfe6922b311cf2a0c1ef3f7db 63 Pfam PF01599 Ribosomal protein S27a 14 56 4.4E-15 T 31-10-2018 IPR002906 Ribosomal protein S27a GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 DFR85_08035 91d7aa9bfe6922b311cf2a0c1ef3f7db 63 SUPERFAMILY SSF57829 13 61 2.38E-15 T 31-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 DFR85_09430 640b43934718bcca48e2e4e6f4595fcf 93 SUPERFAMILY SSF101386 4 92 6.11E-24 T 31-10-2018 DFR85_09430 640b43934718bcca48e2e4e6f4595fcf 93 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 6 91 4.5E-16 T 31-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 DFR85_09430 640b43934718bcca48e2e4e6f4595fcf 93 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 2 88 20.638 T 31-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 DFR85_09430 640b43934718bcca48e2e4e6f4595fcf 93 Gene3D G3DSA:1.10.287.1080 1 93 1.6E-26 T 31-10-2018 DFR85_09430 640b43934718bcca48e2e4e6f4595fcf 93 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 5 88 3.0E-27 T 31-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 DFR85_04020 1ef5b4cc070058c6ac859f3bb9bcc5cf 130 Pfam PF05168 HEPN domain 6 124 2.6E-32 T 31-10-2018 IPR007842 HEPN domain DFR85_04020 1ef5b4cc070058c6ac859f3bb9bcc5cf 130 SMART SM00748 9 118 1.9E-39 T 31-10-2018 IPR007842 HEPN domain DFR85_04020 1ef5b4cc070058c6ac859f3bb9bcc5cf 130 Gene3D G3DSA:1.20.120.330 2 126 1.5E-36 T 31-10-2018 DFR85_04020 1ef5b4cc070058c6ac859f3bb9bcc5cf 130 SUPERFAMILY SSF81593 3 125 6.28E-42 T 31-10-2018 DFR85_13755 ef248d89f841db2b39582174b85b5b90 732 Gene3D G3DSA:3.30.420.350 484 718 5.1E-92 T 31-10-2018 DFR85_13755 ef248d89f841db2b39582174b85b5b90 732 Pfam PF07503 HypF finger 107 140 7.5E-13 T 31-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 DFR85_13755 ef248d89f841db2b39582174b85b5b90 732 Pfam PF07503 HypF finger 157 190 1.7E-14 T 31-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 DFR85_13755 ef248d89f841db2b39582174b85b5b90 732 Gene3D G3DSA:3.90.870.50 6 360 5.1E-131 T 31-10-2018 DFR85_13755 ef248d89f841db2b39582174b85b5b90 732 SUPERFAMILY SSF55821 176 393 3.36E-40 T 31-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily DFR85_13755 ef248d89f841db2b39582174b85b5b90 732 Gene3D G3DSA:3.30.420.360 381 727 5.1E-92 T 31-10-2018 DFR85_13755 ef248d89f841db2b39582174b85b5b90 732 PIRSF PIRSF006256 1 732 2.1E-239 T 31-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 DFR85_13755 ef248d89f841db2b39582174b85b5b90 732 TIGRFAM TIGR00143 hypF: carbamoyltransferase HypF 8 729 1.6E-226 T 31-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 DFR85_13755 ef248d89f841db2b39582174b85b5b90 732 SUPERFAMILY SSF54975 1 89 5.23E-22 T 31-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 DFR85_13755 ef248d89f841db2b39582174b85b5b90 732 Gene3D G3DSA:3.30.110.120 252 369 5.1E-131 T 31-10-2018 DFR85_13755 ef248d89f841db2b39582174b85b5b90 732 Pfam PF00708 Acylphosphatase 4 88 4.1E-19 T 31-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 DFR85_13755 ef248d89f841db2b39582174b85b5b90 732 Pfam PF01300 Telomere recombination 209 381 7.5E-43 T 31-10-2018 IPR006070 YrdC-like domain GO:0003725 DFR85_13755 ef248d89f841db2b39582174b85b5b90 732 SUPERFAMILY SSF53067 417 711 5.48E-9 T 31-10-2018 DFR85_02300 40a3f299cab1dbe5061f4c96fe6d5580 327 SMART SM00382 39 245 1.3E-14 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_02300 40a3f299cab1dbe5061f4c96fe6d5580 327 SUPERFAMILY SSF52540 38 320 6.17E-63 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_02300 40a3f299cab1dbe5061f4c96fe6d5580 327 Pfam PF00005 ABC transporter 30 187 7.4E-28 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR85_02300 40a3f299cab1dbe5061f4c96fe6d5580 327 Gene3D G3DSA:3.40.50.300 8 326 2.0E-97 T 31-10-2018 DFR85_02300 40a3f299cab1dbe5061f4c96fe6d5580 327 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DFR85_02300 40a3f299cab1dbe5061f4c96fe6d5580 327 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 239 303 2.2E-22 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 DFR85_02300 40a3f299cab1dbe5061f4c96fe6d5580 327 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 237 322 1.0E-33 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 DFR85_14345 934eb954ee363e14e7ea4fa4b2da44e4 114 Pfam PF02406 MmoB/DmpM family 26 111 4.2E-22 T 31-10-2018 IPR003454 Monooxygenase component MmoB/DmpM GO:0004497|GO:0006725 DFR85_14345 934eb954ee363e14e7ea4fa4b2da44e4 114 SUPERFAMILY SSF56029 17 113 2.62E-23 T 31-10-2018 IPR036889 Monooxygenase component MmoB/DmpM superfamily GO:0004497|GO:0006725 DFR85_14345 934eb954ee363e14e7ea4fa4b2da44e4 114 ProDom PD004249 MONOOXYGENASE COMPONENT HYDROXYLASE MMOB/DMPM PHENOL SUBUNIT 3D-STRUCTURE HYDROCARBONS IRON PHENOLHYDROXYLASE 46 113 7.0E-24 T 31-10-2018 IPR003454 Monooxygenase component MmoB/DmpM GO:0004497|GO:0006725 DFR85_14345 934eb954ee363e14e7ea4fa4b2da44e4 114 Gene3D G3DSA:3.90.56.10 15 114 4.1E-26 T 31-10-2018 IPR036889 Monooxygenase component MmoB/DmpM superfamily GO:0004497|GO:0006725 DFR85_01090 9f7e3cfc11737bdc88b9ae19b8163455 168 Gene3D G3DSA:1.25.40.350 4 167 5.0E-55 T 31-10-2018 DFR85_01090 9f7e3cfc11737bdc88b9ae19b8163455 168 SUPERFAMILY SSF101424 8 163 3.92E-57 T 31-10-2018 IPR036321 Hypothetical protein ST1625 DFR85_01090 9f7e3cfc11737bdc88b9ae19b8163455 168 Pfam PF09205 Domain of unknown function (DUF1955) 8 163 2.0E-65 T 31-10-2018 IPR015288 Protein of unknown function DUF1955 DFR85_05475 32e4cf019068ff8c1d1063ce7ecbecb8 452 TIGRFAM TIGR03154 sulfolob_CbsA: cytochrome b558/566, subunit A 4 452 9.4E-223 T 31-10-2018 IPR017572 Cytochrome b558/566, subunit A GO:0005886|GO:0016021|GO:0020037|GO:0022900 DFR85_05475 32e4cf019068ff8c1d1063ce7ecbecb8 452 Gene3D G3DSA:2.60.40.1190 312 412 2.8E-8 T 31-10-2018 DFR85_05475 32e4cf019068ff8c1d1063ce7ecbecb8 452 SMART SM00887 53 400 3.5E-71 T 31-10-2018 IPR019020 Cytochrome c-552/DMSO reductase-like, haem-binding domain GO:0020037 DFR85_05475 32e4cf019068ff8c1d1063ce7ecbecb8 452 Pfam PF09459 Ethylbenzene dehydrogenase 53 399 1.4E-33 T 31-10-2018 IPR019020 Cytochrome c-552/DMSO reductase-like, haem-binding domain GO:0020037 DFR85_00040 a098835a7be7d1e3a9404a8ff6ef3f97 563 SUPERFAMILY SSF81342 18 268 7.85E-45 T 31-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 DFR85_00040 a098835a7be7d1e3a9404a8ff6ef3f97 563 Pfam PF13631 Cytochrome b(N-terminal)/b6/petB 92 298 2.7E-54 T 31-10-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 DFR85_00040 a098835a7be7d1e3a9404a8ff6ef3f97 563 SUPERFAMILY SSF81648 232 393 2.29E-12 T 31-10-2018 IPR036150 Cytochrome b/b6, C-terminal domain superfamily GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 DFR85_00040 a098835a7be7d1e3a9404a8ff6ef3f97 563 Gene3D G3DSA:1.20.810.10 25 433 1.1E-64 T 31-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 DFR85_13145 c94f7ffaf2e495216e9d32ebdd4d8c3d 301 TIGRFAM TIGR02590 cas_Csh2: CRISPR-associated protein Cas7/Csh2, subtype I-B/HMARI 12 268 1.6E-61 T 31-10-2018 IPR013419 CRISPR-associated protein Csh2 DFR85_13145 c94f7ffaf2e495216e9d32ebdd4d8c3d 301 Pfam PF05107 CRISPR-associated protein Cas7 12 257 4.9E-50 T 31-10-2018 IPR006482 CRISPR-associated protein Cas7, subtype I-B/I-C DFR85_13145 c94f7ffaf2e495216e9d32ebdd4d8c3d 301 TIGRFAM TIGR01595 cas_CT1132: CRISPR-associated protein, CT1132 family 10 267 8.5E-47 T 31-10-2018 IPR006482 CRISPR-associated protein Cas7, subtype I-B/I-C DFR85_12715 11c186f76546b58e0562eb3885d5782a 257 SUPERFAMILY SSF48208 5 227 3.06E-40 T 31-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 DFR85_12715 11c186f76546b58e0562eb3885d5782a 257 Gene3D G3DSA:1.50.10.10 2 233 1.1E-32 T 31-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 DFR85_12480 828057a7d03c4eb8fc33b033ab096211 436 Gene3D G3DSA:1.20.1740.10 10 433 1.2E-25 T 31-10-2018 DFR85_12480 828057a7d03c4eb8fc33b033ab096211 436 Pfam PF00324 Amino acid permease 23 396 2.0E-13 T 31-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 DFR85_12480 828057a7d03c4eb8fc33b033ab096211 436 PIRSF PIRSF006060 1 432 4.4E-37 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_07170 c04b0ad1b6eca416d8723684bf80e7cf 275 Gene3D G3DSA:3.30.230.70 12 275 3.5E-83 T 31-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 DFR85_07170 c04b0ad1b6eca416d8723684bf80e7cf 275 SUPERFAMILY SSF54211 10 218 5.06E-56 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold DFR85_07170 c04b0ad1b6eca416d8723684bf80e7cf 275 Hamap MF_00622 Exosome complex component Rrp42 [rrp42]. 7 272 44.601 T 31-10-2018 IPR020869 Exosome complex component Rrp42, archaea GO:0000178|GO:0006401 DFR85_07170 c04b0ad1b6eca416d8723684bf80e7cf 275 SUPERFAMILY SSF55666 196 273 3.65E-19 T 31-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 DFR85_07170 c04b0ad1b6eca416d8723684bf80e7cf 275 Pfam PF03725 3' exoribonuclease family, domain 2 196 258 1.0E-10 T 31-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 DFR85_07170 c04b0ad1b6eca416d8723684bf80e7cf 275 Pfam PF01138 3' exoribonuclease family, domain 1 37 171 1.8E-31 T 31-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 DFR85_01220 efe29a019f34d5b7cb92decd9f906700 510 TIGRFAM TIGR02751 PEPCase_arch: phosphoenolpyruvate carboxylase 4 510 4.4E-209 T 31-10-2018 IPR007566 Phosphoenolpyruvate carboxylase, archaeal-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 DFR85_01220 efe29a019f34d5b7cb92decd9f906700 510 PIRSF PIRSF006677 1 510 7.8E-196 T 31-10-2018 IPR007566 Phosphoenolpyruvate carboxylase, archaeal-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 DFR85_01220 efe29a019f34d5b7cb92decd9f906700 510 Pfam PF14010 Phosphoenolpyruvate carboxylase 4 510 2.9E-207 T 31-10-2018 IPR007566 Phosphoenolpyruvate carboxylase, archaeal-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 DFR85_01220 efe29a019f34d5b7cb92decd9f906700 510 Hamap MF_01904 Phosphoenolpyruvate carboxylase [ppcA]. 3 510 39.754 T 31-10-2018 IPR007566 Phosphoenolpyruvate carboxylase, archaeal-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 DFR85_01220 efe29a019f34d5b7cb92decd9f906700 510 SUPERFAMILY SSF51621 128 461 1.22E-36 T 31-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 DFR85_05660 b5dc31d68c4e6f7e18759d5536314745 119 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 16 99 2.8E-8 T 31-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis DFR85_05660 b5dc31d68c4e6f7e18759d5536314745 119 SUPERFAMILY SSF53146 1 117 7.33E-19 T 31-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily DFR85_05660 b5dc31d68c4e6f7e18759d5536314745 119 Gene3D G3DSA:3.30.420.130 1 117 6.7E-36 T 31-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily DFR85_00785 8ab34fc92ecce7d85644456c341ef93b 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 49 64 7.8E-49 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR85_00785 8ab34fc92ecce7d85644456c341ef93b 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 277 295 7.8E-49 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR85_00785 8ab34fc92ecce7d85644456c341ef93b 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 115 123 7.8E-49 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR85_00785 8ab34fc92ecce7d85644456c341ef93b 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 152 176 7.8E-49 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR85_00785 8ab34fc92ecce7d85644456c341ef93b 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 17 39 7.8E-49 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR85_00785 8ab34fc92ecce7d85644456c341ef93b 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 137 149 7.8E-49 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR85_00785 8ab34fc92ecce7d85644456c341ef93b 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 204 220 7.8E-49 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR85_00785 8ab34fc92ecce7d85644456c341ef93b 322 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 242 263 7.8E-49 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR85_00785 8ab34fc92ecce7d85644456c341ef93b 322 Gene3D G3DSA:3.50.50.60 126 248 6.1E-115 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_00785 8ab34fc92ecce7d85644456c341ef93b 322 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 17 305 9.3E-47 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR85_00785 8ab34fc92ecce7d85644456c341ef93b 322 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 144 164 - T 31-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 DFR85_00785 8ab34fc92ecce7d85644456c341ef93b 322 SUPERFAMILY SSF51905 11 316 1.24E-42 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_00785 8ab34fc92ecce7d85644456c341ef93b 322 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 18 37 8.4E-30 T 31-10-2018 DFR85_00785 8ab34fc92ecce7d85644456c341ef93b 322 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 240 256 8.4E-30 T 31-10-2018 DFR85_00785 8ab34fc92ecce7d85644456c341ef93b 322 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 114 132 8.4E-30 T 31-10-2018 DFR85_00785 8ab34fc92ecce7d85644456c341ef93b 322 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 267 289 8.4E-30 T 31-10-2018 DFR85_00785 8ab34fc92ecce7d85644456c341ef93b 322 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 8.4E-30 T 31-10-2018 DFR85_00785 8ab34fc92ecce7d85644456c341ef93b 322 Gene3D G3DSA:3.50.50.60 16 310 6.1E-115 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_07220 4792b56cafbec81e05ef00a0d18ce094 400 SUPERFAMILY SSF53448 2 302 5.63E-59 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_07220 4792b56cafbec81e05ef00a0d18ce094 400 Gene3D G3DSA:2.160.10.10 211 400 2.6E-54 T 31-10-2018 DFR85_07220 4792b56cafbec81e05ef00a0d18ce094 400 Pfam PF00483 Nucleotidyl transferase 2 220 5.6E-33 T 31-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 DFR85_07220 4792b56cafbec81e05ef00a0d18ce094 400 SUPERFAMILY SSF51161 234 397 2.46E-34 T 31-10-2018 IPR011004 Trimeric LpxA-like superfamily DFR85_07220 4792b56cafbec81e05ef00a0d18ce094 400 TIGRFAM TIGR03992 Arch_glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 2 388 9.9E-155 T 31-10-2018 IPR023915 UDP-GlcNAc diphosphorylase/GlcNAc-1-P N-acetyltransferase, GlmU, archaeal-type GO:0003977|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 DFR85_07220 4792b56cafbec81e05ef00a0d18ce094 400 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 355 389 2.7E-4 T 31-10-2018 IPR001451 Hexapeptide repeat DFR85_07220 4792b56cafbec81e05ef00a0d18ce094 400 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 297 330 0.0017 T 31-10-2018 IPR001451 Hexapeptide repeat DFR85_07220 4792b56cafbec81e05ef00a0d18ce094 400 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 244 277 4.1E-8 T 31-10-2018 IPR001451 Hexapeptide repeat DFR85_07220 4792b56cafbec81e05ef00a0d18ce094 400 Gene3D G3DSA:3.90.550.10 1 210 7.2E-56 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_12570 3f244e484f66b6065a5115ecc952e425 236 SUPERFAMILY SSF102198 14 235 6.02E-47 T 31-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 DFR85_12570 3f244e484f66b6065a5115ecc952e425 236 Gene3D G3DSA:3.50.30.50 10 234 2.2E-52 T 31-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 DFR85_12570 3f244e484f66b6065a5115ecc952e425 236 Pfam PF04199 Putative cyclase 17 168 1.8E-23 T 31-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 DFR85_15000 829e1ea64c6d89da24bb33ddfc08a287 243 Gene3D G3DSA:3.40.50.720 1 243 2.2E-85 T 31-10-2018 DFR85_15000 829e1ea64c6d89da24bb33ddfc08a287 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 2.1E-15 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_15000 829e1ea64c6d89da24bb33ddfc08a287 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 2.1E-15 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_15000 829e1ea64c6d89da24bb33ddfc08a287 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 2.1E-15 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_15000 829e1ea64c6d89da24bb33ddfc08a287 243 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 31-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DFR85_15000 829e1ea64c6d89da24bb33ddfc08a287 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 2.9E-46 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_15000 829e1ea64c6d89da24bb33ddfc08a287 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 2.9E-46 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_15000 829e1ea64c6d89da24bb33ddfc08a287 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 2.9E-46 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_15000 829e1ea64c6d89da24bb33ddfc08a287 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 2.9E-46 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_15000 829e1ea64c6d89da24bb33ddfc08a287 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 2.9E-46 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_15000 829e1ea64c6d89da24bb33ddfc08a287 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 2.9E-46 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_15000 829e1ea64c6d89da24bb33ddfc08a287 243 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 8 241 1.0E-65 T 31-10-2018 DFR85_15000 829e1ea64c6d89da24bb33ddfc08a287 243 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 182 0.007 T 31-10-2018 DFR85_15000 829e1ea64c6d89da24bb33ddfc08a287 243 SUPERFAMILY SSF51735 2 242 1.65E-82 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_08410 724e1fc0ff8eb0dfb994a97b86904bf2 135 Gene3D G3DSA:1.10.10.10 8 69 1.5E-11 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_08410 724e1fc0ff8eb0dfb994a97b86904bf2 135 SUPERFAMILY SSF46785 5 76 4.55E-9 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_08410 724e1fc0ff8eb0dfb994a97b86904bf2 135 Pfam PF12840 Helix-turn-helix domain 9 60 1.5E-6 T 31-10-2018 DFR85_06080 8f8fdae0a22fdb14c77aca7c8f65fda0 565 SUPERFAMILY SSF56425 228 344 2.84E-40 T 31-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 DFR85_06080 8f8fdae0a22fdb14c77aca7c8f65fda0 565 Gene3D G3DSA:3.90.700.10 238 339 1.4E-148 T 31-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 DFR85_06080 8f8fdae0a22fdb14c77aca7c8f65fda0 565 Pfam PF02910 Fumarate reductase flavoprotein C-term 441 565 5.1E-44 T 31-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 DFR85_06080 8f8fdae0a22fdb14c77aca7c8f65fda0 565 Pfam PF00890 FAD binding domain 7 385 7.3E-109 T 31-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 DFR85_06080 8f8fdae0a22fdb14c77aca7c8f65fda0 565 Gene3D G3DSA:1.20.58.100 410 527 2.2E-35 T 31-10-2018 DFR85_06080 8f8fdae0a22fdb14c77aca7c8f65fda0 565 PIRSF PIRSF000171 1 562 3.2E-51 T 31-10-2018 DFR85_06080 8f8fdae0a22fdb14c77aca7c8f65fda0 565 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 7 565 2.8E-242 T 31-10-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 DFR85_06080 8f8fdae0a22fdb14c77aca7c8f65fda0 565 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 41 50 - T 31-10-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 DFR85_06080 8f8fdae0a22fdb14c77aca7c8f65fda0 565 SUPERFAMILY SSF51905 4 412 1.23E-67 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_06080 8f8fdae0a22fdb14c77aca7c8f65fda0 565 Gene3D G3DSA:4.10.80.40 528 561 6.1E-8 T 31-10-2018 DFR85_06080 8f8fdae0a22fdb14c77aca7c8f65fda0 565 Gene3D G3DSA:3.50.50.60 7 395 1.4E-148 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_06080 8f8fdae0a22fdb14c77aca7c8f65fda0 565 SUPERFAMILY SSF46977 433 565 1.24E-51 T 31-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 DFR85_11200 54fc6666c69f70e858a4fdce852e9538 290 Gene3D G3DSA:3.60.15.10 2 288 6.4E-68 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR85_11200 54fc6666c69f70e858a4fdce852e9538 290 Hamap MF_01818 Ribonuclease BN [rbn]. 2 289 30.742 T 31-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 DFR85_11200 54fc6666c69f70e858a4fdce852e9538 290 Pfam PF00753 Metallo-beta-lactamase superfamily 21 92 2.3E-9 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR85_11200 54fc6666c69f70e858a4fdce852e9538 290 Pfam PF12706 Beta-lactamase superfamily domain 186 257 2.6E-9 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR85_11200 54fc6666c69f70e858a4fdce852e9538 290 SUPERFAMILY SSF56281 3 284 9.56E-59 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR85_11425 c982551bde497d0ca121fce604a895a4 278 Pfam PF13237 4Fe-4S dicluster domain 60 121 1.2E-7 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR85_11425 c982551bde497d0ca121fce604a895a4 278 Gene3D G3DSA:1.10.1060.10 36 142 7.1E-10 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 DFR85_11425 c982551bde497d0ca121fce604a895a4 278 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 110 121 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR85_11425 c982551bde497d0ca121fce604a895a4 278 SUPERFAMILY SSF46548 46 139 4.19E-16 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 DFR85_03575 42fa37508812b08f75a1da3d39673d36 508 Pfam PF00374 Nickel-dependent hydrogenase 416 496 1.3E-19 T 31-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 DFR85_03575 42fa37508812b08f75a1da3d39673d36 508 Pfam PF00374 Nickel-dependent hydrogenase 38 117 2.8E-11 T 31-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 DFR85_03575 42fa37508812b08f75a1da3d39673d36 508 Gene3D G3DSA:1.10.645.10 2 496 2.0E-103 T 31-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_03575 42fa37508812b08f75a1da3d39673d36 508 SUPERFAMILY SSF56762 4 496 3.79E-56 T 31-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_12645 e04de940c792e8c9f59fe90ebfe74bd3 95 Pfam PF08666 SAF domain 11 89 3.7E-14 T 31-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 DFR85_12645 e04de940c792e8c9f59fe90ebfe74bd3 95 Gene3D G3DSA:3.90.1210.30 5 91 8.0E-29 T 31-10-2018 DFR85_12645 e04de940c792e8c9f59fe90ebfe74bd3 95 SMART SM00858 11 89 8.4E-14 T 31-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 DFR85_05030 8e9d6be9c63a84c8a4ddfd26dc984a0a 97 Pfam PF04693 Archaeal putative transposase ISC1217 2 69 2.9E-26 T 31-10-2018 IPR006783 Transposase, ISC1217 DFR85_14580 5b6ef9266633051ab4859c8ac6c0b8ea 481 Gene3D G3DSA:3.40.309.10 259 447 7.6E-152 T 31-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 DFR85_14580 5b6ef9266633051ab4859c8ac6c0b8ea 481 Pfam PF00171 Aldehyde dehydrogenase family 17 474 3.1E-152 T 31-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 DFR85_14580 5b6ef9266633051ab4859c8ac6c0b8ea 481 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 280 291 - T 31-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 DFR85_14580 5b6ef9266633051ab4859c8ac6c0b8ea 481 Gene3D G3DSA:3.40.605.10 13 466 7.6E-152 T 31-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 DFR85_14580 5b6ef9266633051ab4859c8ac6c0b8ea 481 SUPERFAMILY SSF53720 3 478 4.84E-142 T 31-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 DFR85_02230 eaa84ced498a00f194c8ce7f3e2a6230 251 Pfam PF01061 ABC-2 type transporter 12 203 5.8E-9 T 31-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 DFR85_02740 a3fc5ae3257d18ded61755f779734994 81 SMART SM00966 6 49 1.1E-9 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR85_02740 a3fc5ae3257d18ded61755f779734994 81 SUPERFAMILY SSF89447 4 48 2.09E-12 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily DFR85_02740 a3fc5ae3257d18ded61755f779734994 81 Gene3D G3DSA:2.10.260.10 1 80 2.2E-12 T 31-10-2018 DFR85_02740 a3fc5ae3257d18ded61755f779734994 81 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 5 45 1.3E-16 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR85_02740 a3fc5ae3257d18ded61755f779734994 81 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 6 46 2.6E-11 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR85_14650 f7a3686dbf589be480b8b2bc224a8ad6 104 PIRSF PIRSF000068 1 104 2.7E-41 T 31-10-2018 IPR009157 Ferredoxin zinc-binding GO:0008270|GO:0009055|GO:0051536 DFR85_14650 f7a3686dbf589be480b8b2bc224a8ad6 104 SUPERFAMILY SSF54862 26 102 3.23E-19 T 31-10-2018 DFR85_14650 f7a3686dbf589be480b8b2bc224a8ad6 104 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 84 95 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR85_14650 f7a3686dbf589be480b8b2bc224a8ad6 104 Pfam PF13187 4Fe-4S dicluster domain 46 99 8.4E-9 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR85_14650 f7a3686dbf589be480b8b2bc224a8ad6 104 Gene3D G3DSA:3.30.70.20 2 104 5.8E-43 T 31-10-2018 DFR85_15120 795dddf9e2a06a3faa3b577a441b5d07 353 Gene3D G3DSA:1.10.8.60 201 275 1.4E-25 T 31-10-2018 DFR85_15120 795dddf9e2a06a3faa3b577a441b5d07 353 Pfam PF01637 ATPase domain predominantly from Archaea 5 239 4.7E-24 T 31-10-2018 IPR011579 ATPase domain GO:0005524 DFR85_15120 795dddf9e2a06a3faa3b577a441b5d07 353 Gene3D G3DSA:3.40.50.300 1 200 1.6E-49 T 31-10-2018 DFR85_15120 795dddf9e2a06a3faa3b577a441b5d07 353 SUPERFAMILY SSF46785 280 348 6.8E-17 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_15120 795dddf9e2a06a3faa3b577a441b5d07 353 SUPERFAMILY SSF52540 2 253 1.24E-47 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_15120 795dddf9e2a06a3faa3b577a441b5d07 353 Gene3D G3DSA:1.10.10.10 278 349 2.1E-27 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_11155 b131854f5a14f7c6e42dd1e832f9bf2b 260 Gene3D G3DSA:2.40.50.140 1 84 1.2E-27 T 31-10-2018 DFR85_11155 b131854f5a14f7c6e42dd1e832f9bf2b 260 Gene3D G3DSA:3.30.70.1130 175 259 4.3E-17 T 31-10-2018 IPR024055 Translation initiation factor 2, alpha subunit, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 DFR85_11155 b131854f5a14f7c6e42dd1e832f9bf2b 260 Gene3D G3DSA:1.10.150.190 85 174 2.4E-27 T 31-10-2018 IPR024054 Translation initiation factor 2, alpha subunit, middle domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 DFR85_11155 b131854f5a14f7c6e42dd1e832f9bf2b 260 Pfam PF07541 Eukaryotic translation initiation factor 2 alpha subunit 122 227 2.1E-19 T 31-10-2018 IPR011488 Translation initiation factor 2, alpha subunit GO:0003723|GO:0003743 Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 DFR85_11155 b131854f5a14f7c6e42dd1e832f9bf2b 260 SUPERFAMILY SSF110993 177 256 1.03E-16 T 31-10-2018 IPR024055 Translation initiation factor 2, alpha subunit, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 DFR85_11155 b131854f5a14f7c6e42dd1e832f9bf2b 260 SMART SM00316 10 83 7.2E-17 T 31-10-2018 IPR022967 RNA-binding domain, S1 DFR85_11155 b131854f5a14f7c6e42dd1e832f9bf2b 260 Pfam PF00575 S1 RNA binding domain 9 83 3.5E-12 T 31-10-2018 IPR003029 S1 domain GO:0003676 DFR85_11155 b131854f5a14f7c6e42dd1e832f9bf2b 260 SUPERFAMILY SSF116742 85 171 3.92E-23 T 31-10-2018 IPR024054 Translation initiation factor 2, alpha subunit, middle domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 DFR85_11155 b131854f5a14f7c6e42dd1e832f9bf2b 260 SUPERFAMILY SSF50249 8 88 2.79E-19 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR85_01040 133326494f03fbda7373eea870628dc8 481 PIRSF PIRSF019435 1 481 2.2E-135 T 31-10-2018 IPR008508 Protein of unknown function DUF790, endonuclease-like DFR85_01040 133326494f03fbda7373eea870628dc8 481 Pfam PF05626 Protein of unknown function (DUF790) 2 374 6.2E-114 T 31-10-2018 IPR008508 Protein of unknown function DUF790, endonuclease-like DFR85_00685 522b514276fb626aba3a644df9309b0f 519 Pfam PF13183 4Fe-4S dicluster domain 81 138 9.8E-9 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR85_00685 522b514276fb626aba3a644df9309b0f 519 SUPERFAMILY SSF46548 63 146 1.92E-15 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 DFR85_00685 522b514276fb626aba3a644df9309b0f 519 Gene3D G3DSA:1.10.1060.10 58 149 1.4E-7 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 DFR85_00685 522b514276fb626aba3a644df9309b0f 519 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 124 135 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR85_00600 7630ef448f739359e7db6d5105a15517 252 ProSitePatterns PS01245 RIO1/ZK632.3/MJ0444 family signature. 181 192 - T 31-10-2018 IPR018935 RIO kinase, conserved site GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 DFR85_00600 7630ef448f739359e7db6d5105a15517 252 SUPERFAMILY SSF56112 45 228 7.6E-25 T 31-10-2018 IPR011009 Protein kinase-like domain superfamily DFR85_00600 7630ef448f739359e7db6d5105a15517 252 SMART SM00090 13 243 7.5E-77 T 31-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 DFR85_00600 7630ef448f739359e7db6d5105a15517 252 Pfam PF01163 RIO1 family 55 240 6.0E-64 T 31-10-2018 DFR85_00600 7630ef448f739359e7db6d5105a15517 252 Gene3D G3DSA:1.10.510.10 149 251 2.0E-30 T 31-10-2018 DFR85_00600 7630ef448f739359e7db6d5105a15517 252 Gene3D G3DSA:3.30.200.20 44 143 2.3E-13 T 31-10-2018 DFR85_11035 55b976ddbc98fa5af75ffc76950d8ef5 67 Gene3D G3DSA:3.40.5.90 1 63 2.4E-17 T 31-10-2018 DFR85_11035 55b976ddbc98fa5af75ffc76950d8ef5 67 SMART SM00704 10 47 1.2E-8 T 31-10-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 DFR85_11035 55b976ddbc98fa5af75ffc76950d8ef5 67 Pfam PF09360 Iron-binding zinc finger CDGSH type 10 42 1.2E-11 T 31-10-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 DFR85_07970 ba6bc5cfe7ae6d2b184376d6c8a656e6 1221 Pfam PF01751 Toprim domain 612 772 1.1E-26 T 31-10-2018 IPR006171 TOPRIM domain DFR85_07970 ba6bc5cfe7ae6d2b184376d6c8a656e6 1221 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1134 1148 3.7E-25 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 DFR85_07970 ba6bc5cfe7ae6d2b184376d6c8a656e6 1221 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 937 946 3.7E-25 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 DFR85_07970 ba6bc5cfe7ae6d2b184376d6c8a656e6 1221 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 736 749 3.7E-25 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 DFR85_07970 ba6bc5cfe7ae6d2b184376d6c8a656e6 1221 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1021 1037 3.7E-25 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 DFR85_07970 ba6bc5cfe7ae6d2b184376d6c8a656e6 1221 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 835 853 3.7E-25 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 DFR85_07970 ba6bc5cfe7ae6d2b184376d6c8a656e6 1221 SUPERFAMILY SSF52540 13 249 2.14E-25 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_07970 ba6bc5cfe7ae6d2b184376d6c8a656e6 1221 Hamap MF_01125 Reverse gyrase [rgy]. 7 1221 59.981 T 31-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 DFR85_07970 ba6bc5cfe7ae6d2b184376d6c8a656e6 1221 SMART SM00487 84 314 1.8E-21 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain DFR85_07970 ba6bc5cfe7ae6d2b184376d6c8a656e6 1221 SMART SM00436 763 865 7.6E-37 T 31-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 DFR85_07970 ba6bc5cfe7ae6d2b184376d6c8a656e6 1221 SUPERFAMILY SSF52540 304 590 2.69E-33 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_07970 ba6bc5cfe7ae6d2b184376d6c8a656e6 1221 TIGRFAM TIGR01054 rgy: reverse gyrase 9 1220 0.0 T 31-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 DFR85_07970 ba6bc5cfe7ae6d2b184376d6c8a656e6 1221 Gene3D G3DSA:3.40.50.300 67 297 4.8E-61 T 31-10-2018 DFR85_07970 ba6bc5cfe7ae6d2b184376d6c8a656e6 1221 Gene3D G3DSA:2.60.510.20 857 1118 1.7E-130 T 31-10-2018 DFR85_07970 ba6bc5cfe7ae6d2b184376d6c8a656e6 1221 SMART SM00437 895 1173 1.8E-81 T 31-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 DFR85_07970 ba6bc5cfe7ae6d2b184376d6c8a656e6 1221 Pfam PF01131 DNA topoisomerase 790 1211 1.1E-71 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 DFR85_07970 ba6bc5cfe7ae6d2b184376d6c8a656e6 1221 Gene3D G3DSA:1.10.290.10 905 1032 1.7E-130 T 31-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 DFR85_07970 ba6bc5cfe7ae6d2b184376d6c8a656e6 1221 Pfam PF00270 DEAD/DEAH box helicase 92 282 1.1E-13 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 DFR85_07970 ba6bc5cfe7ae6d2b184376d6c8a656e6 1221 SMART SM00493 610 762 2.8E-35 T 31-10-2018 IPR006171 TOPRIM domain DFR85_07970 ba6bc5cfe7ae6d2b184376d6c8a656e6 1221 Gene3D G3DSA:3.40.50.300 502 599 1.1E-12 T 31-10-2018 DFR85_07970 ba6bc5cfe7ae6d2b184376d6c8a656e6 1221 Gene3D G3DSA:3.40.50.300 299 476 5.3E-30 T 31-10-2018 DFR85_07970 ba6bc5cfe7ae6d2b184376d6c8a656e6 1221 Gene3D G3DSA:3.40.50.140 600 786 4.9E-31 T 31-10-2018 DFR85_07970 ba6bc5cfe7ae6d2b184376d6c8a656e6 1221 Gene3D G3DSA:1.10.460.10 792 1214 1.7E-130 T 31-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 DFR85_07970 ba6bc5cfe7ae6d2b184376d6c8a656e6 1221 SUPERFAMILY SSF56712 607 1219 2.88E-127 T 31-10-2018 IPR023405 DNA topoisomerase, type IA, core domain DFR85_06405 6301d5c703aca75e68263be08efa001a 711 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 129 655 2.2E-150 T 31-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DFR85_06405 6301d5c703aca75e68263be08efa001a 711 Gene3D G3DSA:3.30.365.10 342 694 6.8E-106 T 31-10-2018 DFR85_06405 6301d5c703aca75e68263be08efa001a 711 Gene3D G3DSA:3.90.1170.50 2 106 9.0E-39 T 31-10-2018 DFR85_06405 6301d5c703aca75e68263be08efa001a 711 SUPERFAMILY SSF56003 99 706 3.93E-175 T 31-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 DFR85_06405 6301d5c703aca75e68263be08efa001a 711 Gene3D G3DSA:3.30.365.10 162 254 7.2E-71 T 31-10-2018 DFR85_06405 6301d5c703aca75e68263be08efa001a 711 SMART SM01008 18 107 9.5E-29 T 31-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DFR85_06405 6301d5c703aca75e68263be08efa001a 711 SUPERFAMILY SSF54665 2 112 1.44E-30 T 31-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily DFR85_06405 6301d5c703aca75e68263be08efa001a 711 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 18 107 1.5E-13 T 31-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DFR85_06405 6301d5c703aca75e68263be08efa001a 711 Gene3D G3DSA:3.30.365.10 123 333 7.2E-71 T 31-10-2018 DFR85_06405 6301d5c703aca75e68263be08efa001a 711 Gene3D G3DSA:3.30.365.10 422 570 6.8E-106 T 31-10-2018 DFR85_15150 ec262856d0c2023f8324f5ff4c4f7e85 135 Gene3D G3DSA:3.30.300.130 1 82 2.2E-8 T 31-10-2018 IPR034904 Fe-S cluster assembly domain superfamily DFR85_15150 ec262856d0c2023f8324f5ff4c4f7e85 135 SUPERFAMILY SSF117916 3 61 4.58E-9 T 31-10-2018 IPR034904 Fe-S cluster assembly domain superfamily DFR85_00425 e0df56ca90febdad069863abd1b50dee 278 Pfam PF12679 ABC-2 family transporter protein 60 273 8.0E-11 T 31-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 DFR85_01025 3319af699fae661c7ddde9d0d9589237 468 Gene3D G3DSA:3.40.50.300 19 282 1.0E-20 T 31-10-2018 DFR85_01025 3319af699fae661c7ddde9d0d9589237 468 Pfam PF13614 AAA domain 20 149 1.1E-11 T 31-10-2018 IPR025669 AAA domain DFR85_01025 3319af699fae661c7ddde9d0d9589237 468 SUPERFAMILY SSF52540 18 272 4.73E-22 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_01025 3319af699fae661c7ddde9d0d9589237 468 Gene3D G3DSA:3.40.50.300 286 456 2.5E-6 T 31-10-2018 DFR85_08280 11a4708cb8c3a02106ec6153e4abc089 117 Pfam PF06677 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) 10 46 2.1E-13 T 31-10-2018 IPR009563 Sjoegren syndrome/scleroderma autoantigen 1 DFR85_03630 30c4d7b906909a4c4118b673546829a0 285 Pfam PF01925 Sulfite exporter TauE/SafE 11 276 1.2E-43 T 31-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 DFR85_11740 5f89cc0a4b8b3c33db45ac60d73fea7b 313 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 3 304 4.5E-73 T 31-10-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain DFR85_11740 5f89cc0a4b8b3c33db45ac60d73fea7b 313 Gene3D G3DSA:3.90.245.10 2 313 1.6E-104 T 31-10-2018 IPR036452 Ribonucleoside hydrolase-like DFR85_11740 5f89cc0a4b8b3c33db45ac60d73fea7b 313 SUPERFAMILY SSF53590 3 311 2.88E-86 T 31-10-2018 IPR036452 Ribonucleoside hydrolase-like DFR85_11375 02c7c9345da9720176ae7cfd9f68a532 107 Gene3D G3DSA:1.10.10.10 2 107 2.0E-37 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_11375 02c7c9345da9720176ae7cfd9f68a532 107 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 14 77 3.1E-8 T 31-10-2018 IPR002831 Transcription regulator TrmB, N-terminal DFR85_11375 02c7c9345da9720176ae7cfd9f68a532 107 SUPERFAMILY SSF46785 11 84 1.07E-12 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_00105 bdd391b43cd5eefc92a401606c87e0ce 255 SUPERFAMILY SSF52540 2 199 1.17E-33 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_00105 bdd391b43cd5eefc92a401606c87e0ce 255 Pfam PF00005 ABC transporter 22 149 1.5E-19 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR85_00105 bdd391b43cd5eefc92a401606c87e0ce 255 SMART SM00382 24 198 1.7E-9 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_00105 bdd391b43cd5eefc92a401606c87e0ce 255 Gene3D G3DSA:3.40.50.300 1 254 4.1E-52 T 31-10-2018 DFR85_15840 4ad18f05ea4654256d10467b1526f3df 307 PIRSF PIRSF000102 1 301 2.6E-77 T 31-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 DFR85_15840 4ad18f05ea4654256d10467b1526f3df 307 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 2 134 5.9E-32 T 31-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 DFR85_15840 4ad18f05ea4654256d10467b1526f3df 307 Gene3D G3DSA:3.90.110.10 141 296 1.0E-29 T 31-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 DFR85_15840 4ad18f05ea4654256d10467b1526f3df 307 SUPERFAMILY SSF51735 3 134 1.03E-36 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_15840 4ad18f05ea4654256d10467b1526f3df 307 SUPERFAMILY SSF56327 140 295 1.59E-31 T 31-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 DFR85_15840 4ad18f05ea4654256d10467b1526f3df 307 PRINTS PR00086 L-lactate dehydrogenase signature 28 52 5.7E-13 T 31-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 DFR85_15840 4ad18f05ea4654256d10467b1526f3df 307 PRINTS PR00086 L-lactate dehydrogenase signature 116 136 5.7E-13 T 31-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 DFR85_15840 4ad18f05ea4654256d10467b1526f3df 307 PRINTS PR00086 L-lactate dehydrogenase signature 167 180 5.7E-13 T 31-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 DFR85_15840 4ad18f05ea4654256d10467b1526f3df 307 PRINTS PR00086 L-lactate dehydrogenase signature 3 27 5.7E-13 T 31-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 DFR85_15840 4ad18f05ea4654256d10467b1526f3df 307 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 146 293 5.0E-7 T 31-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 DFR85_15840 4ad18f05ea4654256d10467b1526f3df 307 Gene3D G3DSA:3.40.50.720 1 138 2.4E-36 T 31-10-2018 DFR85_05165 e82b38f55d5d1ebc778103c6f462756c 350 Pfam PF00534 Glycosyl transferases group 1 185 331 1.2E-17 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 DFR85_05165 e82b38f55d5d1ebc778103c6f462756c 350 SUPERFAMILY SSF53756 95 348 3.05E-38 T 31-10-2018 DFR85_05165 e82b38f55d5d1ebc778103c6f462756c 350 Gene3D G3DSA:3.40.50.2000 40 180 1.8E-5 T 31-10-2018 DFR85_05165 e82b38f55d5d1ebc778103c6f462756c 350 Gene3D G3DSA:3.40.50.2000 181 334 1.5E-23 T 31-10-2018 DFR85_07090 59858568abc661fd78854c9b883c3497 238 Gene3D G3DSA:4.10.950.10 159 238 3.7E-37 T 31-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07090 59858568abc661fd78854c9b883c3497 238 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 89 215 2.2E-42 T 31-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 DFR85_07090 59858568abc661fd78854c9b883c3497 238 SMART SM01382 87 220 5.3E-61 T 31-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 DFR85_07090 59858568abc661fd78854c9b883c3497 238 SUPERFAMILY SSF50249 2 86 1.75E-15 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR85_07090 59858568abc661fd78854c9b883c3497 238 PIRSF PIRSF002158 1 238 9.0E-65 T 31-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_07090 59858568abc661fd78854c9b883c3497 238 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 11 80 1.4E-12 T 31-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_07090 59858568abc661fd78854c9b883c3497 238 SUPERFAMILY SSF50104 90 234 9.63E-50 T 31-10-2018 IPR008991 Translation protein SH3-like domain superfamily DFR85_07090 59858568abc661fd78854c9b883c3497 238 SMART SM01383 11 81 1.0E-14 T 31-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_07090 59858568abc661fd78854c9b883c3497 238 Gene3D G3DSA:2.40.50.140 1 76 4.4E-19 T 31-10-2018 DFR85_07090 59858568abc661fd78854c9b883c3497 238 Hamap MF_01320_A 50S ribosomal protein L2 [rplB]. 1 235 37.456 T 31-10-2018 IPR023672 Ribosomal protein L2, archaeal-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07090 59858568abc661fd78854c9b883c3497 238 Gene3D G3DSA:2.30.30.30 81 158 1.5E-24 T 31-10-2018 IPR014722 Ribosomal protein L2, domain 2 DFR85_11970 cd8030d8911d8ba0a782cf94b2a07dbc 126 SUPERFAMILY SSF46785 16 115 2.81E-11 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_11970 cd8030d8911d8ba0a782cf94b2a07dbc 126 Pfam PF02002 TFIIE alpha subunit 15 119 4.6E-9 T 31-10-2018 IPR024550 TFIIEalpha/SarR/Rpc3 HTH domain Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 DFR85_11970 cd8030d8911d8ba0a782cf94b2a07dbc 126 Gene3D G3DSA:1.10.10.10 12 117 3.4E-26 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_09005 10745d7dc35554a2f1c4273c273746c0 228 Gene3D G3DSA:3.40.50.10320 4 227 2.9E-46 T 31-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 DFR85_09005 10745d7dc35554a2f1c4273c273746c0 228 SUPERFAMILY SSF102588 14 214 2.88E-41 T 31-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 DFR85_09005 10745d7dc35554a2f1c4273c273746c0 228 Pfam PF02585 GlcNAc-PI de-N-acetylase 17 144 4.0E-30 T 31-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 DFR85_01965 1000e90ccbc55debaede88c579f5a476 462 Pfam PF13537 Glutamine amidotransferase domain 90 199 5.2E-14 T 31-10-2018 IPR017932 Glutamine amidotransferase type 2 domain DFR85_01965 1000e90ccbc55debaede88c579f5a476 462 Pfam PF06508 Queuosine biosynthesis protein QueC 242 451 6.0E-59 T 31-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 DFR85_01965 1000e90ccbc55debaede88c579f5a476 462 SUPERFAMILY SSF56235 2 227 1.25E-24 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR85_01965 1000e90ccbc55debaede88c579f5a476 462 Gene3D G3DSA:3.60.20.10 2 240 6.2E-31 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR85_01965 1000e90ccbc55debaede88c579f5a476 462 SUPERFAMILY SSF52402 241 460 1.48E-49 T 31-10-2018 DFR85_01965 1000e90ccbc55debaede88c579f5a476 462 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 243 445 5.1E-48 T 31-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 DFR85_01965 1000e90ccbc55debaede88c579f5a476 462 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 241 458 43.752 T 31-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 DFR85_01965 1000e90ccbc55debaede88c579f5a476 462 Gene3D G3DSA:3.40.50.620 241 453 4.1E-58 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR85_11495 6d4295edfe7916d570f6ebc01f711815 142 Pfam PF05168 HEPN domain 11 131 3.4E-21 T 31-10-2018 IPR007842 HEPN domain DFR85_11495 6d4295edfe7916d570f6ebc01f711815 142 SUPERFAMILY SSF81593 13 136 3.41E-23 T 31-10-2018 DFR85_11495 6d4295edfe7916d570f6ebc01f711815 142 Gene3D G3DSA:1.20.120.330 5 139 2.3E-17 T 31-10-2018 DFR85_11495 6d4295edfe7916d570f6ebc01f711815 142 SMART SM00748 14 128 8.3E-4 T 31-10-2018 IPR007842 HEPN domain DFR85_07490 e1ce0c1045e3b05545307a5f37b089c5 54 SUPERFAMILY SSF47598 8 49 5.23E-6 T 31-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 DFR85_07490 e1ce0c1045e3b05545307a5f37b089c5 54 Pfam PF01402 Ribbon-helix-helix protein, copG family 10 48 1.4E-6 T 31-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 DFR85_02430 3ea547c8d94d6a8c9e21cc61563b0be3 435 Gene3D G3DSA:1.20.1740.10 2 434 7.5E-73 T 31-10-2018 DFR85_02430 3ea547c8d94d6a8c9e21cc61563b0be3 435 PIRSF PIRSF006060 2 434 9.6E-68 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_02430 3ea547c8d94d6a8c9e21cc61563b0be3 435 Pfam PF13520 Amino acid permease 5 415 3.7E-38 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_05235 960b259939af3c557931c41d4e971c80 267 Pfam PF06157 Protein of unknown function (DUF973) 4 266 1.1E-55 T 31-10-2018 IPR009321 Protein of unknown function DUF973 DFR85_01315 41c51d29f951747536ea0c52f9129aef 326 Pfam PF00149 Calcineurin-like phosphoesterase 19 282 5.4E-5 T 31-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 DFR85_01315 41c51d29f951747536ea0c52f9129aef 326 SUPERFAMILY SSF56300 19 323 8.55E-73 T 31-10-2018 DFR85_01315 41c51d29f951747536ea0c52f9129aef 326 Gene3D G3DSA:3.60.21.10 80 324 4.7E-21 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like DFR85_05280 24ba75f9f1c65fd02757677d7bdde365 409 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 155 1.1E-9 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR85_05280 24ba75f9f1c65fd02757677d7bdde365 409 Gene3D G3DSA:3.50.50.60 115 276 3.2E-102 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_05280 24ba75f9f1c65fd02757677d7bdde365 409 Gene3D G3DSA:3.50.50.60 4 332 3.2E-102 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_05280 24ba75f9f1c65fd02757677d7bdde365 409 SUPERFAMILY SSF51905 129 336 1.89E-12 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_05280 24ba75f9f1c65fd02757677d7bdde365 409 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 211 324 2.4E-8 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR85_05280 24ba75f9f1c65fd02757677d7bdde365 409 SUPERFAMILY SSF51905 3 333 1.1E-23 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_05420 3dedec4baeff76980b42fd9020debe3e 103 SUPERFAMILY SSF143011 32 100 7.06E-10 T 31-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily DFR85_05420 3dedec4baeff76980b42fd9020debe3e 103 Gene3D G3DSA:3.30.2310.20 9 103 5.4E-7 T 31-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily DFR85_05420 3dedec4baeff76980b42fd9020debe3e 103 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 17 101 5.0E-6 T 31-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family DFR85_08040 9d1ad077e4cf84965f9979ec47889fce 121 SUPERFAMILY SSF54189 16 112 2.41E-25 T 31-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_08040 9d1ad077e4cf84965f9979ec47889fce 121 Hamap MF_00545 30S ribosomal protein S24e [rps24e]. 6 112 18.275 T 31-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_08040 9d1ad077e4cf84965f9979ec47889fce 121 ProDom PD006052 RIBOSOMAL S24 40S RIBONUCLEOPROTEIN S24E 30S S24 CDNA RIKEN ACETYLATION 24 93 6.0E-18 T 31-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_08040 9d1ad077e4cf84965f9979ec47889fce 121 Gene3D G3DSA:3.30.70.330 7 111 1.9E-23 T 31-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily DFR85_08040 9d1ad077e4cf84965f9979ec47889fce 121 Pfam PF01282 Ribosomal protein S24e 34 109 1.9E-19 T 31-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_02750 2831ca2be521739c7d507975b9dc03dc 312 Gene3D G3DSA:1.10.1530.10 22 59 4.7E-53 T 31-10-2018 DFR85_02750 2831ca2be521739c7d507975b9dc03dc 312 Gene3D G3DSA:3.30.60.50 178 226 4.7E-53 T 31-10-2018 DFR85_02750 2831ca2be521739c7d507975b9dc03dc 312 SUPERFAMILY SSF89733 1 306 1.23E-50 T 31-10-2018 IPR036111 Malate/L-sulfolactate/L-lactate dehydrogenase-like superfamily GO:0016491|GO:0055114 DFR85_02750 2831ca2be521739c7d507975b9dc03dc 312 Pfam PF02615 Malate/L-lactate dehydrogenase 4 245 2.8E-51 T 31-10-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0016491|GO:0055114 DFR85_02750 2831ca2be521739c7d507975b9dc03dc 312 Gene3D G3DSA:3.30.1370.60 60 245 4.7E-53 T 31-10-2018 DFR85_11615 3362509941786e1d57abb04fe77c41aa 569 SUPERFAMILY SSF51011 503 566 6.91E-7 T 31-10-2018 DFR85_11615 3362509941786e1d57abb04fe77c41aa 569 Pfam PF00128 Alpha amylase, catalytic domain 233 435 3.3E-5 T 31-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 DFR85_11615 3362509941786e1d57abb04fe77c41aa 569 Pfam PF00128 Alpha amylase, catalytic domain 122 209 2.2E-23 T 31-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 DFR85_11615 3362509941786e1d57abb04fe77c41aa 569 SUPERFAMILY SSF51445 91 500 7.43E-103 T 31-10-2018 IPR017853 Glycoside hydrolase superfamily DFR85_11615 3362509941786e1d57abb04fe77c41aa 569 SUPERFAMILY SSF81296 7 88 3.27E-10 T 31-10-2018 IPR014756 Immunoglobulin E-set DFR85_11615 3362509941786e1d57abb04fe77c41aa 569 Gene3D G3DSA:1.10.10.760 441 475 4.0E-162 T 31-10-2018 DFR85_11615 3362509941786e1d57abb04fe77c41aa 569 Gene3D G3DSA:3.20.20.80 100 498 4.0E-162 T 31-10-2018 DFR85_11615 3362509941786e1d57abb04fe77c41aa 569 SMART SM00642 112 456 3.7E-11 T 31-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 DFR85_11615 3362509941786e1d57abb04fe77c41aa 569 Pfam PF09071 Alpha-amylase, C terminal 503 566 5.6E-10 T 31-10-2018 IPR015156 Malto-oligosyltrehalose trehalohydrolase, archaeal, C-terminal KEGG: 00500+3.2.1.141|MetaCyc: PWY-2661 DFR85_11615 3362509941786e1d57abb04fe77c41aa 569 PIRSF PIRSF006337 4 561 2.8E-209 T 31-10-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|MetaCyc: PWY-2661 DFR85_11615 3362509941786e1d57abb04fe77c41aa 569 TIGRFAM TIGR02402 trehalose_TreZ: malto-oligosyltrehalose trehalohydrolase 17 531 3.0E-206 T 31-10-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|MetaCyc: PWY-2661 DFR85_11615 3362509941786e1d57abb04fe77c41aa 569 Gene3D G3DSA:2.60.40.10 6 90 5.3E-18 T 31-10-2018 IPR013783 Immunoglobulin-like fold DFR85_11285 92fd04dc53dab717fdd294093880c353 540 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 215 424 1.6E-41 T 31-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR85_11285 92fd04dc53dab717fdd294093880c353 540 Gene3D G3DSA:3.30.930.10 114 426 2.5E-120 T 31-10-2018 DFR85_11285 92fd04dc53dab717fdd294093880c353 540 Pfam PF03129 Anticodon binding domain 436 524 2.0E-16 T 31-10-2018 IPR004154 Anticodon-binding DFR85_11285 92fd04dc53dab717fdd294093880c353 540 PRINTS PR01047 Threonyl-tRNA synthetase signature 402 415 3.3E-52 T 31-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 DFR85_11285 92fd04dc53dab717fdd294093880c353 540 PRINTS PR01047 Threonyl-tRNA synthetase signature 255 278 3.3E-52 T 31-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 DFR85_11285 92fd04dc53dab717fdd294093880c353 540 PRINTS PR01047 Threonyl-tRNA synthetase signature 429 441 3.3E-52 T 31-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 DFR85_11285 92fd04dc53dab717fdd294093880c353 540 PRINTS PR01047 Threonyl-tRNA synthetase signature 359 387 3.3E-52 T 31-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 DFR85_11285 92fd04dc53dab717fdd294093880c353 540 PRINTS PR01047 Threonyl-tRNA synthetase signature 222 250 3.3E-52 T 31-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 DFR85_11285 92fd04dc53dab717fdd294093880c353 540 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 3 528 29.059 T 31-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 DFR85_11285 92fd04dc53dab717fdd294093880c353 540 SUPERFAMILY SSF55681 135 421 2.59E-88 T 31-10-2018 DFR85_11285 92fd04dc53dab717fdd294093880c353 540 SUPERFAMILY SSF52954 424 528 1.15E-25 T 31-10-2018 DFR85_11285 92fd04dc53dab717fdd294093880c353 540 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 102 525 2.6E-160 T 31-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 DFR85_11285 92fd04dc53dab717fdd294093880c353 540 SUPERFAMILY SSF55186 24 132 1.26E-5 T 31-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 DFR85_11285 92fd04dc53dab717fdd294093880c353 540 Gene3D G3DSA:3.40.50.800 427 537 1.3E-27 T 31-10-2018 IPR036621 Anticodon-binding domain superfamily DFR85_08890 9b9b9a8133a847a75b9eb7475ba87f58 262 ProSitePatterns PS00446 RNA polymerases D / 30 to 40 Kd subunits signature. 26 66 - T 31-10-2018 IPR001514 DNA-directed RNA polymerase, 30-40kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 DFR85_08890 9b9b9a8133a847a75b9eb7475ba87f58 262 Hamap MF_00320 DNA-directed RNA polymerase subunit D [rpoD]. 1 261 31.824 T 31-10-2018 IPR022842 DNA-directed RNA polymerase subunit D (Rpo3) GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR85_08890 9b9b9a8133a847a75b9eb7475ba87f58 262 Gene3D G3DSA:3.30.1360.10 13 255 3.6E-93 T 31-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR85_08890 9b9b9a8133a847a75b9eb7475ba87f58 262 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 16 252 6.5E-10 T 31-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR85_08890 9b9b9a8133a847a75b9eb7475ba87f58 262 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 44 157 1.5E-30 T 31-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR85_08890 9b9b9a8133a847a75b9eb7475ba87f58 262 SMART SM00662 12 258 1.3E-85 T 31-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR85_08890 9b9b9a8133a847a75b9eb7475ba87f58 262 Gene3D G3DSA:3.30.70.20 167 222 3.6E-93 T 31-10-2018 DFR85_08890 9b9b9a8133a847a75b9eb7475ba87f58 262 SUPERFAMILY SSF56553 37 158 4.71E-34 T 31-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR85_08890 9b9b9a8133a847a75b9eb7475ba87f58 262 SUPERFAMILY SSF55257 2 260 1.61E-23 T 31-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR85_08890 9b9b9a8133a847a75b9eb7475ba87f58 262 Gene3D G3DSA:2.170.120.12 38 156 3.6E-93 T 31-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR85_11875 dbbd744751cb59d30473cc7676d76559 291 PIRSF PIRSF018978 1 288 1.6E-36 T 31-10-2018 IPR016742 tRNA methyltransferase, archaea GO:0008175|GO:0030488 DFR85_11875 dbbd744751cb59d30473cc7676d76559 291 Gene3D G3DSA:3.40.1280.30 75 247 2.6E-7 T 31-10-2018 IPR038459 tRNA methyltransferase TRM10-type domain superfamily DFR85_09590 df7c7445ab948c0937831a5a3942f441 463 SUPERFAMILY SSF52540 80 356 2.71E-82 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_09590 df7c7445ab948c0937831a5a3942f441 463 Hamap MF_00310 V-type ATP synthase beta chain [atpB]. 4 460 59.576 T 31-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 DFR85_09590 df7c7445ab948c0937831a5a3942f441 463 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 133 351 2.3E-64 T 31-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 DFR85_09590 df7c7445ab948c0937831a5a3942f441 463 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 10 76 3.7E-12 T 31-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 DFR85_09590 df7c7445ab948c0937831a5a3942f441 463 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 342 351 - T 31-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 DFR85_09590 df7c7445ab948c0937831a5a3942f441 463 PIRSF PIRSF039114 1 463 5.6E-235 T 31-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 DFR85_09590 df7c7445ab948c0937831a5a3942f441 463 Gene3D G3DSA:3.40.50.12240 1 460 3.2E-174 T 31-10-2018 DFR85_08690 e5e463e86aec76cf5f01f8c05c30d0cc 401 Pfam PF00155 Aminotransferase class I and II 62 392 8.7E-41 T 31-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 DFR85_08690 e5e463e86aec76cf5f01f8c05c30d0cc 401 Gene3D G3DSA:3.40.640.10 67 292 1.2E-140 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR85_08690 e5e463e86aec76cf5f01f8c05c30d0cc 401 SUPERFAMILY SSF53383 5 399 3.09E-108 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase DFR85_08690 e5e463e86aec76cf5f01f8c05c30d0cc 401 Gene3D G3DSA:3.90.1150.10 20 397 1.2E-140 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 DFR85_14310 ee36b9b020e009bd5db2d7d7b4986023 560 Pfam PF07690 Major Facilitator Superfamily 14 423 9.1E-39 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_14310 ee36b9b020e009bd5db2d7d7b4986023 560 Gene3D G3DSA:1.20.1720.10 11 233 1.1E-30 T 31-10-2018 DFR85_14310 ee36b9b020e009bd5db2d7d7b4986023 560 Gene3D G3DSA:1.20.1250.20 280 538 7.8E-17 T 31-10-2018 DFR85_14310 ee36b9b020e009bd5db2d7d7b4986023 560 SUPERFAMILY SSF103473 3 432 7.72E-52 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_06110 50dee5ed363ac213032e04447019fc27 151 Gene3D G3DSA:2.40.50.140 1 117 8.3E-33 T 31-10-2018 DFR85_06110 50dee5ed363ac213032e04447019fc27 151 SUPERFAMILY SSF50249 4 107 1.89E-28 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR85_06110 50dee5ed363ac213032e04447019fc27 151 Pfam PF01336 OB-fold nucleic acid binding domain 15 87 6.8E-7 T 31-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 DFR85_09625 171434013d31fcc8e027b48f5d551abe 192 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 68 90 - T 31-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 DFR85_09625 171434013d31fcc8e027b48f5d551abe 192 Gene3D G3DSA:1.20.120.1760 6 191 7.4E-44 T 31-10-2018 DFR85_09625 171434013d31fcc8e027b48f5d551abe 192 Pfam PF01066 CDP-alcohol phosphatidyltransferase 26 90 2.9E-11 T 31-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 DFR85_00430 27379230a984947348c285a48c49e8db 304 Pfam PF00005 ABC transporter 21 158 9.6E-29 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR85_00430 27379230a984947348c285a48c49e8db 304 Gene3D G3DSA:3.40.50.300 4 230 1.8E-56 T 31-10-2018 DFR85_00430 27379230a984947348c285a48c49e8db 304 SUPERFAMILY SSF52540 6 222 1.04E-53 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_00430 27379230a984947348c285a48c49e8db 304 SMART SM00382 30 216 4.2E-12 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_13615 ffe787472066745a25a69f0a24fe7db7 93 Pfam PF14947 Winged helix-turn-helix 5 79 3.8E-25 T 31-10-2018 IPR038723 ArnR1-like, winged helix-turn-helix domain DFR85_13615 ffe787472066745a25a69f0a24fe7db7 93 SUPERFAMILY SSF46785 6 88 3.1E-12 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_13615 ffe787472066745a25a69f0a24fe7db7 93 Gene3D G3DSA:1.10.10.10 3 93 1.9E-26 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_05810 97ab7a5a13cb4b40a8b17fb0c0f048f5 151 PRINTS PR00700 Protein tyrosine phosphatase signature 90 108 3.4E-7 T 31-10-2018 IPR000242 PTP type protein phosphatase GO:0004725|GO:0006470 DFR85_05810 97ab7a5a13cb4b40a8b17fb0c0f048f5 151 PRINTS PR00700 Protein tyrosine phosphatase signature 116 131 3.4E-7 T 31-10-2018 IPR000242 PTP type protein phosphatase GO:0004725|GO:0006470 DFR85_05810 97ab7a5a13cb4b40a8b17fb0c0f048f5 151 PRINTS PR00700 Protein tyrosine phosphatase signature 132 142 3.4E-7 T 31-10-2018 IPR000242 PTP type protein phosphatase GO:0004725|GO:0006470 DFR85_05810 97ab7a5a13cb4b40a8b17fb0c0f048f5 151 Pfam PF00782 Dual specificity phosphatase, catalytic domain 54 144 3.7E-12 T 31-10-2018 IPR000340 Dual specificity phosphatase, catalytic domain GO:0008138|GO:0016311 DFR85_05810 97ab7a5a13cb4b40a8b17fb0c0f048f5 151 SMART SM00404 58 148 6.3E-12 T 31-10-2018 IPR003595 Protein-tyrosine phosphatase, catalytic DFR85_05810 97ab7a5a13cb4b40a8b17fb0c0f048f5 151 Gene3D G3DSA:3.90.190.10 1 149 2.0E-40 T 31-10-2018 IPR029021 Protein-tyrosine phosphatase-like DFR85_05810 97ab7a5a13cb4b40a8b17fb0c0f048f5 151 SUPERFAMILY SSF52799 2 145 4.9E-34 T 31-10-2018 IPR029021 Protein-tyrosine phosphatase-like DFR85_05810 97ab7a5a13cb4b40a8b17fb0c0f048f5 151 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 93 103 - T 31-10-2018 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311 DFR85_05810 97ab7a5a13cb4b40a8b17fb0c0f048f5 151 SMART SM01301 4 113 0.0038 T 31-10-2018 DFR85_05810 97ab7a5a13cb4b40a8b17fb0c0f048f5 151 SMART SM00195 30 148 0.0015 T 31-10-2018 IPR020422 Dual specificity protein phosphatase domain GO:0006470|GO:0008138 DFR85_09355 f41f1e633de74fcb4a862541108c2991 297 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 2 139 4.1E-37 T 31-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 DFR85_09355 f41f1e633de74fcb4a862541108c2991 297 PRINTS PR00101 Aspartate carbamoyltransferase signature 276 290 3.2E-31 T 31-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 DFR85_09355 f41f1e633de74fcb4a862541108c2991 297 PRINTS PR00101 Aspartate carbamoyltransferase signature 33 55 3.2E-31 T 31-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 DFR85_09355 f41f1e633de74fcb4a862541108c2991 297 PRINTS PR00101 Aspartate carbamoyltransferase signature 126 143 3.2E-31 T 31-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 DFR85_09355 f41f1e633de74fcb4a862541108c2991 297 PRINTS PR00101 Aspartate carbamoyltransferase signature 72 81 3.2E-31 T 31-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 DFR85_09355 f41f1e633de74fcb4a862541108c2991 297 PRINTS PR00101 Aspartate carbamoyltransferase signature 254 259 3.2E-31 T 31-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 DFR85_09355 f41f1e633de74fcb4a862541108c2991 297 PRINTS PR00101 Aspartate carbamoyltransferase signature 215 224 3.2E-31 T 31-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 DFR85_09355 f41f1e633de74fcb4a862541108c2991 297 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 127 138 2.6E-16 T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 DFR85_09355 f41f1e633de74fcb4a862541108c2991 297 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 250 259 2.6E-16 T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 DFR85_09355 f41f1e633de74fcb4a862541108c2991 297 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 260 283 2.6E-16 T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 DFR85_09355 f41f1e633de74fcb4a862541108c2991 297 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 43 62 2.6E-16 T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 DFR85_09355 f41f1e633de74fcb4a862541108c2991 297 Gene3D G3DSA:3.40.50.1370 128 275 2.0E-103 T 31-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 DFR85_09355 f41f1e633de74fcb4a862541108c2991 297 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 2 295 2.2E-102 T 31-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 DFR85_09355 f41f1e633de74fcb4a862541108c2991 297 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 147 292 7.6E-23 T 31-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 DFR85_09355 f41f1e633de74fcb4a862541108c2991 297 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 1 297 34.29 T 31-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 DFR85_09355 f41f1e633de74fcb4a862541108c2991 297 ProSitePatterns PS00018 EF-hand calcium-binding domain. 9 21 - T 31-10-2018 IPR018247 EF-Hand 1, calcium-binding site DFR85_09355 f41f1e633de74fcb4a862541108c2991 297 Gene3D G3DSA:3.40.50.1370 3 291 2.0E-103 T 31-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 DFR85_09355 f41f1e633de74fcb4a862541108c2991 297 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 43 50 - T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 DFR85_09355 f41f1e633de74fcb4a862541108c2991 297 SUPERFAMILY SSF53671 2 296 5.11E-84 T 31-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 DFR85_15100 d942c35cb21517e8c65c9ce805031e45 183 Pfam PF08241 Methyltransferase domain 42 146 6.6E-18 T 31-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 DFR85_15100 d942c35cb21517e8c65c9ce805031e45 183 SUPERFAMILY SSF53335 16 152 5.83E-26 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR85_15100 d942c35cb21517e8c65c9ce805031e45 183 Gene3D G3DSA:3.40.50.150 6 182 3.9E-27 T 31-10-2018 DFR85_09795 1c333ab6d74c90fd1145400cc747cdef 266 SUPERFAMILY SSF55060 204 252 2.45E-8 T 31-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily DFR85_09795 1c333ab6d74c90fd1145400cc747cdef 266 Pfam PF08544 GHMP kinases C terminal 207 245 8.8E-5 T 31-10-2018 IPR013750 GHMP kinase, C-terminal domain DFR85_09795 1c333ab6d74c90fd1145400cc747cdef 266 Pfam PF00288 GHMP kinases N terminal domain 60 126 5.3E-11 T 31-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 DFR85_09795 1c333ab6d74c90fd1145400cc747cdef 266 TIGRFAM TIGR01920 Shik_kin_archae: shikimate kinase 4 250 2.1E-78 T 31-10-2018 IPR010189 Shikimate kinase, archaea GO:0004765|GO:0005737|GO:0009073 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 DFR85_09795 1c333ab6d74c90fd1145400cc747cdef 266 Gene3D G3DSA:3.30.230.10 7 141 8.1E-18 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup DFR85_09795 1c333ab6d74c90fd1145400cc747cdef 266 SUPERFAMILY SSF54211 19 150 2.05E-15 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold DFR85_09795 1c333ab6d74c90fd1145400cc747cdef 266 PIRSF PIRSF005758 1 262 8.5E-88 T 31-10-2018 IPR010189 Shikimate kinase, archaea GO:0004765|GO:0005737|GO:0009073 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 DFR85_09795 1c333ab6d74c90fd1145400cc747cdef 266 Hamap MF_00370 Shikimate kinase [aroK]. 1 266 86.492 T 31-10-2018 IPR010189 Shikimate kinase, archaea GO:0004765|GO:0005737|GO:0009073 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 DFR85_13120 1896ebc991f99060596cf4c84124a6b4 751 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 278 578 1.5E-35 T 31-10-2018 IPR006474 Helicase Cas3, CRISPR-associated, core DFR85_13120 1896ebc991f99060596cf4c84124a6b4 751 SUPERFAMILY SSF109604 20 90 1.85E-6 T 31-10-2018 DFR85_13120 1896ebc991f99060596cf4c84124a6b4 751 SMART SM00487 250 464 5.1E-8 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain DFR85_13120 1896ebc991f99060596cf4c84124a6b4 751 Pfam PF00270 DEAD/DEAH box helicase 278 431 4.8E-12 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 DFR85_13120 1896ebc991f99060596cf4c84124a6b4 751 Gene3D G3DSA:3.40.50.300 241 442 1.6E-14 T 31-10-2018 DFR85_13120 1896ebc991f99060596cf4c84124a6b4 751 Gene3D G3DSA:1.10.3210.30 5 203 2.3E-20 T 31-10-2018 IPR038257 CRISPR-associated Cas3-type HD domain superfamily DFR85_13120 1896ebc991f99060596cf4c84124a6b4 751 Gene3D G3DSA:3.40.50.300 443 598 2.9E-5 T 31-10-2018 DFR85_13120 1896ebc991f99060596cf4c84124a6b4 751 SUPERFAMILY SSF52540 277 570 5.71E-26 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_13120 1896ebc991f99060596cf4c84124a6b4 751 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 20 227 5.5E-21 T 31-10-2018 IPR006483 CRISPR-associated Cas3-type HD domain DFR85_06395 62d3bdcca7f1b6f35511e002d08405ff 236 Pfam PF00535 Glycosyl transferase family 2 11 170 1.4E-26 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 DFR85_06395 62d3bdcca7f1b6f35511e002d08405ff 236 SUPERFAMILY SSF53448 10 234 7.36E-39 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_06395 62d3bdcca7f1b6f35511e002d08405ff 236 Gene3D G3DSA:3.90.550.10 2 235 2.6E-44 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_01045 e75d48cd24127262b3d2d21dac632943 206 Gene3D G3DSA:3.40.50.1000 6 193 3.4E-34 T 31-10-2018 IPR023214 HAD superfamily DFR85_01045 e75d48cd24127262b3d2d21dac632943 206 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 174 2.2E-28 T 31-10-2018 DFR85_01045 e75d48cd24127262b3d2d21dac632943 206 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 5 165 2.0E-7 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 DFR85_01045 e75d48cd24127262b3d2d21dac632943 206 Gene3D G3DSA:1.10.150.240 17 77 3.4E-34 T 31-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 DFR85_01045 e75d48cd24127262b3d2d21dac632943 206 ProSitePatterns PS01228 Hypothetical cof family signature 1. 4 15 - T 31-10-2018 DFR85_01045 e75d48cd24127262b3d2d21dac632943 206 SUPERFAMILY SSF56784 1 204 9.98E-40 T 31-10-2018 IPR036412 HAD-like superfamily DFR85_10650 b1f2b7584c4d96631479cab66dc8e39d 306 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 151 304 9.3E-49 T 31-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 DFR85_10650 b1f2b7584c4d96631479cab66dc8e39d 306 SUPERFAMILY SSF53671 2 305 9.43E-86 T 31-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 DFR85_10650 b1f2b7584c4d96631479cab66dc8e39d 306 PRINTS PR00102 Ornithine carbamoyltransferase signature 285 296 4.9E-25 T 31-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 DFR85_10650 b1f2b7584c4d96631479cab66dc8e39d 306 PRINTS PR00102 Ornithine carbamoyltransferase signature 223 233 4.9E-25 T 31-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 DFR85_10650 b1f2b7584c4d96631479cab66dc8e39d 306 PRINTS PR00102 Ornithine carbamoyltransferase signature 121 135 4.9E-25 T 31-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 DFR85_10650 b1f2b7584c4d96631479cab66dc8e39d 306 PRINTS PR00102 Ornithine carbamoyltransferase signature 81 94 4.9E-25 T 31-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 DFR85_10650 b1f2b7584c4d96631479cab66dc8e39d 306 PRINTS PR00102 Ornithine carbamoyltransferase signature 48 62 4.9E-25 T 31-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 DFR85_10650 b1f2b7584c4d96631479cab66dc8e39d 306 Gene3D G3DSA:3.40.50.1370 5 134 4.9E-101 T 31-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 DFR85_10650 b1f2b7584c4d96631479cab66dc8e39d 306 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 5 145 1.4E-40 T 31-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 DFR85_10650 b1f2b7584c4d96631479cab66dc8e39d 306 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 132 143 6.9E-24 T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 DFR85_10650 b1f2b7584c4d96631479cab66dc8e39d 306 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 259 268 6.9E-24 T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 DFR85_10650 b1f2b7584c4d96631479cab66dc8e39d 306 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 50 69 6.9E-24 T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 DFR85_10650 b1f2b7584c4d96631479cab66dc8e39d 306 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 271 294 6.9E-24 T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 DFR85_10650 b1f2b7584c4d96631479cab66dc8e39d 306 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 50 57 - T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 DFR85_10650 b1f2b7584c4d96631479cab66dc8e39d 306 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 5 305 3.1E-106 T 31-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 DFR85_10650 b1f2b7584c4d96631479cab66dc8e39d 306 Gene3D G3DSA:3.40.50.1370 135 301 4.9E-101 T 31-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 DFR85_04140 d63d6062f45bdef436e35a62ee71ee6c 322 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DFR85_04140 d63d6062f45bdef436e35a62ee71ee6c 322 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 296 3.5E-13 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 DFR85_04140 d63d6062f45bdef436e35a62ee71ee6c 322 Pfam PF00005 ABC transporter 26 184 1.7E-27 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR85_04140 d63d6062f45bdef436e35a62ee71ee6c 322 SUPERFAMILY SSF52540 6 257 3.08E-56 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_04140 d63d6062f45bdef436e35a62ee71ee6c 322 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 235 315 3.4E-16 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 DFR85_04140 d63d6062f45bdef436e35a62ee71ee6c 322 Gene3D G3DSA:3.40.50.300 4 322 5.4E-83 T 31-10-2018 DFR85_04140 d63d6062f45bdef436e35a62ee71ee6c 322 SMART SM00382 35 234 5.5E-16 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_13000 37e0215d84880362c7c7f83e2db00815 249 SMART SM00116 10 57 2.6E-4 T 31-10-2018 IPR000644 CBS domain DFR85_13000 37e0215d84880362c7c7f83e2db00815 249 SMART SM00116 199 245 7.7E-11 T 31-10-2018 IPR000644 CBS domain DFR85_13000 37e0215d84880362c7c7f83e2db00815 249 SMART SM00116 137 184 3.1E-8 T 31-10-2018 IPR000644 CBS domain DFR85_13000 37e0215d84880362c7c7f83e2db00815 249 SMART SM00116 75 122 4.0E-8 T 31-10-2018 IPR000644 CBS domain DFR85_13000 37e0215d84880362c7c7f83e2db00815 249 SUPERFAMILY SSF54631 60 184 3.23E-29 T 31-10-2018 DFR85_13000 37e0215d84880362c7c7f83e2db00815 249 Gene3D G3DSA:3.10.580.10 1 126 3.9E-25 T 31-10-2018 DFR85_13000 37e0215d84880362c7c7f83e2db00815 249 SUPERFAMILY SSF54631 192 248 1.98E-13 T 31-10-2018 DFR85_13000 37e0215d84880362c7c7f83e2db00815 249 Pfam PF00571 CBS domain 130 183 6.1E-8 T 31-10-2018 IPR000644 CBS domain DFR85_13000 37e0215d84880362c7c7f83e2db00815 249 Pfam PF00571 CBS domain 197 243 1.0E-13 T 31-10-2018 IPR000644 CBS domain DFR85_13000 37e0215d84880362c7c7f83e2db00815 249 Pfam PF00571 CBS domain 3 57 3.2E-7 T 31-10-2018 IPR000644 CBS domain DFR85_13000 37e0215d84880362c7c7f83e2db00815 249 Pfam PF00571 CBS domain 68 117 1.2E-8 T 31-10-2018 IPR000644 CBS domain DFR85_13000 37e0215d84880362c7c7f83e2db00815 249 Gene3D G3DSA:3.10.580.10 128 248 3.0E-31 T 31-10-2018 DFR85_13000 37e0215d84880362c7c7f83e2db00815 249 SUPERFAMILY SSF54631 2 61 7.46E-9 T 31-10-2018 DFR85_03345 a1bc428f25d1e8c53389fd8290e62c1a 523 SUPERFAMILY SSF52467 159 343 5.06E-15 T 31-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily DFR85_03345 a1bc428f25d1e8c53389fd8290e62c1a 523 Gene3D G3DSA:3.40.50.1220 189 330 3.8E-12 T 31-10-2018 DFR85_03345 a1bc428f25d1e8c53389fd8290e62c1a 523 SUPERFAMILY SSF52518 13 180 1.15E-31 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR85_03345 a1bc428f25d1e8c53389fd8290e62c1a 523 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 173 1.3E-40 T 31-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 DFR85_03345 a1bc428f25d1e8c53389fd8290e62c1a 523 SUPERFAMILY SSF52518 379 520 7.42E-21 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR85_03345 a1bc428f25d1e8c53389fd8290e62c1a 523 Gene3D G3DSA:3.40.50.970 331 523 5.9E-22 T 31-10-2018 DFR85_03345 a1bc428f25d1e8c53389fd8290e62c1a 523 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 378 517 1.1E-15 T 31-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 DFR85_03345 a1bc428f25d1e8c53389fd8290e62c1a 523 Gene3D G3DSA:3.40.50.970 2 179 8.8E-42 T 31-10-2018 DFR85_10815 aa3003e4d9ff17e229e1caf8d4fde185 254 Hamap MF_01084 Diphthine synthase [dphB]. 3 254 28.162 T 31-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 DFR85_10815 aa3003e4d9ff17e229e1caf8d4fde185 254 TIGRFAM TIGR00522 dph5: diphthine synthase 4 251 1.0E-61 T 31-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 DFR85_10815 aa3003e4d9ff17e229e1caf8d4fde185 254 Gene3D G3DSA:3.30.950.10 115 254 3.1E-34 T 31-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 DFR85_10815 aa3003e4d9ff17e229e1caf8d4fde185 254 SUPERFAMILY SSF53790 4 248 9.81E-49 T 31-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 DFR85_10815 aa3003e4d9ff17e229e1caf8d4fde185 254 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 223 1.9E-23 T 31-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 DFR85_10815 aa3003e4d9ff17e229e1caf8d4fde185 254 PIRSF PIRSF036432 3 254 7.7E-83 T 31-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 DFR85_10815 aa3003e4d9ff17e229e1caf8d4fde185 254 Gene3D G3DSA:3.40.1010.10 1 114 1.0E-30 T 31-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 DFR85_07060 8a8e752551cf26cc9cfd74657eb2bdad 112 Pfam PF00366 Ribosomal protein S17 39 106 5.6E-20 T 31-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_07060 8a8e752551cf26cc9cfd74657eb2bdad 112 Hamap MF_01345_A 30S ribosomal protein S17 [rpsQ]. 5 110 32.241 T 31-10-2018 IPR019978 Ribosomal protein S17, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_07060 8a8e752551cf26cc9cfd74657eb2bdad 112 SUPERFAMILY SSF50249 33 109 7.28E-20 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR85_07060 8a8e752551cf26cc9cfd74657eb2bdad 112 Gene3D G3DSA:2.40.50.1000 2 111 6.4E-33 T 31-10-2018 DFR85_07060 8a8e752551cf26cc9cfd74657eb2bdad 112 PRINTS PR00973 Ribosomal protein S17 family signature 86 96 3.3E-8 T 31-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_07060 8a8e752551cf26cc9cfd74657eb2bdad 112 PRINTS PR00973 Ribosomal protein S17 family signature 53 76 3.3E-8 T 31-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_07060 8a8e752551cf26cc9cfd74657eb2bdad 112 PRINTS PR00973 Ribosomal protein S17 family signature 96 103 3.3E-8 T 31-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_07060 8a8e752551cf26cc9cfd74657eb2bdad 112 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 36 98 1.0E-23 T 31-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_07060 8a8e752551cf26cc9cfd74657eb2bdad 112 TIGRFAM TIGR03630 uS17_arch: ribosomal protein uS17 7 108 2.6E-45 T 31-10-2018 IPR028333 Ribosomal protein S17, archaeal/eukaryotic Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_11305 153fa997331ff35e0b6761669368f399 280 SUPERFAMILY SSF52210 119 277 1.2E-41 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 DFR85_11305 153fa997331ff35e0b6761669368f399 280 SMART SM00881 1 96 1.2E-35 T 31-10-2018 IPR003781 CoA-binding GO:0048037 DFR85_11305 153fa997331ff35e0b6761669368f399 280 Gene3D G3DSA:3.40.50.261 120 280 9.0E-61 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 DFR85_11305 153fa997331ff35e0b6761669368f399 280 PRINTS PR01798 Succinyl-CoA synthase signature 78 95 7.5E-28 T 31-10-2018 DFR85_11305 153fa997331ff35e0b6761669368f399 280 PRINTS PR01798 Succinyl-CoA synthase signature 202 215 7.5E-28 T 31-10-2018 DFR85_11305 153fa997331ff35e0b6761669368f399 280 PRINTS PR01798 Succinyl-CoA synthase signature 171 189 7.5E-28 T 31-10-2018 DFR85_11305 153fa997331ff35e0b6761669368f399 280 PRINTS PR01798 Succinyl-CoA synthase signature 235 252 7.5E-28 T 31-10-2018 DFR85_11305 153fa997331ff35e0b6761669368f399 280 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 148 175 - T 31-10-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site DFR85_11305 153fa997331ff35e0b6761669368f399 280 Pfam PF02629 CoA binding domain 2 95 2.5E-32 T 31-10-2018 IPR003781 CoA-binding GO:0048037 DFR85_11305 153fa997331ff35e0b6761669368f399 280 SUPERFAMILY SSF51735 1 118 8.34E-41 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_11305 153fa997331ff35e0b6761669368f399 280 Pfam PF00549 CoA-ligase 147 264 3.5E-14 T 31-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 DFR85_11305 153fa997331ff35e0b6761669368f399 280 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 1 279 1.4E-115 T 31-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 DFR85_11305 153fa997331ff35e0b6761669368f399 280 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 280 37.164 T 31-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 DFR85_11305 153fa997331ff35e0b6761669368f399 280 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 231 244 - T 31-10-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site DFR85_11305 153fa997331ff35e0b6761669368f399 280 Gene3D G3DSA:3.40.50.720 1 119 4.5E-51 T 31-10-2018 DFR85_11305 153fa997331ff35e0b6761669368f399 280 PIRSF PIRSF001553 1 280 5.2E-122 T 31-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 DFR85_09700 b599cedbdcd7e1e328f5d0f4b778a05a 161 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 30 151 2.2E-33 T 31-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_09700 b599cedbdcd7e1e328f5d0f4b778a05a 161 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 30 151 1.7E-37 T 31-10-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_09700 b599cedbdcd7e1e328f5d0f4b778a05a 161 Gene3D G3DSA:3.30.460.80 1 131 1.2E-32 T 31-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_09700 b599cedbdcd7e1e328f5d0f4b778a05a 161 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 88 139 4.0E-17 T 31-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_09700 b599cedbdcd7e1e328f5d0f4b778a05a 161 SUPERFAMILY SSF143243 10 150 7.45E-40 T 31-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_09695 03255f93d3b5f8ddec680775b0e0ef45 392 Gene3D G3DSA:1.10.645.20 10 392 1.9E-130 T 31-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_09695 03255f93d3b5f8ddec680775b0e0ef45 392 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 123 392 2.3E-91 T 31-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_09695 03255f93d3b5f8ddec680775b0e0ef45 392 SUPERFAMILY SSF56762 22 392 2.88E-109 T 31-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_09695 03255f93d3b5f8ddec680775b0e0ef45 392 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 45 56 - T 31-10-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_09260 6149d6501e4fe7dacc05cd3344649090 477 SUPERFAMILY SSF52440 1 107 4.32E-19 T 31-10-2018 IPR016185 Pre-ATP-grasp domain superfamily DFR85_09260 6149d6501e4fe7dacc05cd3344649090 477 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 109 312 1.1E-38 T 31-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 DFR85_09260 6149d6501e4fe7dacc05cd3344649090 477 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 348 439 9.4E-7 T 31-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 DFR85_09260 6149d6501e4fe7dacc05cd3344649090 477 SMART SM01210 346 441 2.1E-8 T 31-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 DFR85_09260 6149d6501e4fe7dacc05cd3344649090 477 SUPERFAMILY SSF56059 109 340 1.34E-32 T 31-10-2018 DFR85_09260 6149d6501e4fe7dacc05cd3344649090 477 SMART SM01209 108 312 2.4E-61 T 31-10-2018 DFR85_09260 6149d6501e4fe7dacc05cd3344649090 477 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 439 6.4E-95 T 31-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 DFR85_09260 6149d6501e4fe7dacc05cd3344649090 477 Gene3D G3DSA:3.90.600.10 347 453 4.0E-8 T 31-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 DFR85_09260 6149d6501e4fe7dacc05cd3344649090 477 SUPERFAMILY SSF51246 345 440 6.12E-10 T 31-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 DFR85_09260 6149d6501e4fe7dacc05cd3344649090 477 Gene3D G3DSA:3.30.1490.20 127 202 3.3E-9 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 DFR85_09260 6149d6501e4fe7dacc05cd3344649090 477 Gene3D G3DSA:3.30.470.20 203 345 1.1E-34 T 31-10-2018 DFR85_09260 6149d6501e4fe7dacc05cd3344649090 477 Gene3D G3DSA:3.40.50.20 2 100 1.4E-18 T 31-10-2018 DFR85_09260 6149d6501e4fe7dacc05cd3344649090 477 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 107 9.4E-20 T 31-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 DFR85_07755 9a88967831b85a25a448aace742fa38a 105 ProSitePatterns PS00993 Ribosomal protein L30e signature 2. 73 93 - T 31-10-2018 IPR022991 Ribosomal protein L30e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07755 9a88967831b85a25a448aace742fa38a 105 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 8 98 6.3E-15 T 31-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 DFR85_07755 9a88967831b85a25a448aace742fa38a 105 Gene3D G3DSA:3.30.1330.30 4 102 2.8E-32 T 31-10-2018 IPR029064 50S ribosomal protein L30e-like DFR85_07755 9a88967831b85a25a448aace742fa38a 105 ProSitePatterns PS00709 Ribosomal protein L30e signature 1. 17 41 - T 31-10-2018 IPR022991 Ribosomal protein L30e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07755 9a88967831b85a25a448aace742fa38a 105 SUPERFAMILY SSF55315 6 99 2.36E-22 T 31-10-2018 IPR029064 50S ribosomal protein L30e-like DFR85_07755 9a88967831b85a25a448aace742fa38a 105 Hamap MF_00481 50S ribosomal protein L30e [rpl30e]. 5 102 27.896 T 31-10-2018 IPR000231 Ribosomal protein L30e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_04425 e24bc37ab3cff85c66ef9c234f4a65bb 672 Pfam PF12215 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term 13 294 1.5E-21 T 31-10-2018 IPR024462 Glycosyl-hydrolase family 116, N-terminal KEGG: 00511+3.2.1.45|KEGG: 00600+3.2.1.45|Reactome: R-HSA-1660662 DFR85_04425 e24bc37ab3cff85c66ef9c234f4a65bb 672 SUPERFAMILY SSF48208 357 641 2.45E-32 T 31-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 DFR85_04425 e24bc37ab3cff85c66ef9c234f4a65bb 672 Gene3D G3DSA:1.50.10.10 358 665 1.7E-23 T 31-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 DFR85_04425 e24bc37ab3cff85c66ef9c234f4a65bb 672 Pfam PF04685 Glycosyl-hydrolase family 116, catalytic region 331 669 4.6E-63 T 31-10-2018 IPR006775 Glycosyl-hydrolase family 116, catalytic region GO:0004553 KEGG: 00511+3.2.1.45|KEGG: 00600+3.2.1.45|Reactome: R-HSA-1660662 DFR85_08120 7241e596d63a4cfb793336e55931e065 298 Gene3D G3DSA:2.40.30.10 133 247 1.1E-15 T 31-10-2018 DFR85_08120 7241e596d63a4cfb793336e55931e065 298 SUPERFAMILY SSF50447 137 217 1.16E-13 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily DFR85_04005 7239872145d7ca4ab6cc8ee644333f15 401 Pfam PF01385 Probable transposase 181 287 4.4E-20 T 31-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 DFR85_04005 7239872145d7ca4ab6cc8ee644333f15 401 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 255 330 3.3E-15 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR85_04005 7239872145d7ca4ab6cc8ee644333f15 401 Pfam PF07282 Putative transposase DNA-binding domain 305 372 3.0E-23 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR85_07135 d3f6a24eeb047e8f8df52f89f39aec1a 241 SUPERFAMILY SSF56784 9 241 1.87E-39 T 31-10-2018 IPR036412 HAD-like superfamily DFR85_07135 d3f6a24eeb047e8f8df52f89f39aec1a 241 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 10 21 1.4E-7 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 DFR85_07135 d3f6a24eeb047e8f8df52f89f39aec1a 241 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 123 136 1.4E-7 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 DFR85_07135 d3f6a24eeb047e8f8df52f89f39aec1a 241 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 203 216 1.4E-7 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 DFR85_07135 d3f6a24eeb047e8f8df52f89f39aec1a 241 Pfam PF13419 Haloacid dehalogenase-like hydrolase 13 213 5.3E-27 T 31-10-2018 DFR85_07135 d3f6a24eeb047e8f8df52f89f39aec1a 241 Gene3D G3DSA:3.40.50.1000 12 237 2.3E-43 T 31-10-2018 IPR023214 HAD superfamily DFR85_07135 d3f6a24eeb047e8f8df52f89f39aec1a 241 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 96 208 9.9E-10 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 DFR85_07135 d3f6a24eeb047e8f8df52f89f39aec1a 241 Gene3D G3DSA:1.10.150.520 24 111 2.3E-43 T 31-10-2018 DFR85_15725 d6a16bad8c1e42a92458d8c30b70060b 471 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 348 356 - T 31-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 DFR85_15725 d6a16bad8c1e42a92458d8c30b70060b 471 Gene3D G3DSA:3.30.465.10 60 176 1.8E-32 T 31-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 DFR85_15725 d6a16bad8c1e42a92458d8c30b70060b 471 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 185 282 4.1E-5 T 31-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal DFR85_15725 d6a16bad8c1e42a92458d8c30b70060b 471 SUPERFAMILY SSF54292 312 387 5.64E-20 T 31-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 DFR85_15725 d6a16bad8c1e42a92458d8c30b70060b 471 SMART SM01092 181 285 3.7E-6 T 31-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal DFR85_15725 d6a16bad8c1e42a92458d8c30b70060b 471 Gene3D G3DSA:3.30.390.50 184 285 3.9E-9 T 31-10-2018 DFR85_15725 d6a16bad8c1e42a92458d8c30b70060b 471 Gene3D G3DSA:1.10.150.120 386 462 1.7E-21 T 31-10-2018 DFR85_15725 d6a16bad8c1e42a92458d8c30b70060b 471 Gene3D G3DSA:3.10.20.30 303 385 6.0E-25 T 31-10-2018 IPR012675 Beta-grasp domain superfamily DFR85_15725 d6a16bad8c1e42a92458d8c30b70060b 471 SUPERFAMILY SSF47741 382 462 8.5E-24 T 31-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily DFR85_15725 d6a16bad8c1e42a92458d8c30b70060b 471 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 316 364 9.7E-9 T 31-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 DFR85_15725 d6a16bad8c1e42a92458d8c30b70060b 471 Pfam PF01799 [2Fe-2S] binding domain 382 452 2.3E-20 T 31-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 DFR85_15725 d6a16bad8c1e42a92458d8c30b70060b 471 Gene3D G3DSA:3.30.43.10 7 58 1.3E-17 T 31-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 DFR85_15725 d6a16bad8c1e42a92458d8c30b70060b 471 SUPERFAMILY SSF56176 7 176 2.18E-47 T 31-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 DFR85_15725 d6a16bad8c1e42a92458d8c30b70060b 471 SUPERFAMILY SSF55447 183 283 6.02E-10 T 31-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily DFR85_15725 d6a16bad8c1e42a92458d8c30b70060b 471 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 10 176 1.2E-47 T 31-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 DFR85_15195 0f1bac644578f300cd0a92147a5c9ee4 149 SUPERFAMILY SSF54909 61 141 4.29E-15 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel DFR85_15195 0f1bac644578f300cd0a92147a5c9ee4 149 Pfam PF01037 Lrp/AsnC ligand binding domain 72 139 1.1E-13 T 31-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DFR85_15195 0f1bac644578f300cd0a92147a5c9ee4 149 SUPERFAMILY SSF46785 1 61 2.81E-15 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_15195 0f1bac644578f300cd0a92147a5c9ee4 149 Gene3D G3DSA:1.10.10.10 1 52 5.9E-18 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_15195 0f1bac644578f300cd0a92147a5c9ee4 149 SMART SM00344 1 109 3.6E-30 T 31-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 DFR85_15195 0f1bac644578f300cd0a92147a5c9ee4 149 Gene3D G3DSA:3.30.70.920 54 146 1.7E-22 T 31-10-2018 DFR85_15195 0f1bac644578f300cd0a92147a5c9ee4 149 Pfam PF13412 Winged helix-turn-helix DNA-binding 2 48 1.5E-13 T 31-10-2018 DFR85_15195 0f1bac644578f300cd0a92147a5c9ee4 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 1.8E-9 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR85_15195 0f1bac644578f300cd0a92147a5c9ee4 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 1.8E-9 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR85_09730 a2a0ecbb55a547dd9bf34943ef585ce8 358 Gene3D G3DSA:2.160.10.10 232 354 5.5E-17 T 31-10-2018 DFR85_09730 a2a0ecbb55a547dd9bf34943ef585ce8 358 Pfam PF00483 Nucleotidyl transferase 4 222 1.0E-32 T 31-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 DFR85_09730 a2a0ecbb55a547dd9bf34943ef585ce8 358 SUPERFAMILY SSF53448 1 307 1.74E-66 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_09730 a2a0ecbb55a547dd9bf34943ef585ce8 358 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 251 282 0.0017 T 31-10-2018 IPR001451 Hexapeptide repeat DFR85_09730 a2a0ecbb55a547dd9bf34943ef585ce8 358 Gene3D G3DSA:3.90.550.10 2 231 1.2E-63 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_03315 1f839f4b950c9c27e6fe9870182422be 405 SUPERFAMILY SSF56176 13 204 3.78E-28 T 31-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 DFR85_03315 1f839f4b950c9c27e6fe9870182422be 405 SUPERFAMILY SSF55103 305 404 5.72E-7 T 31-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 DFR85_03315 1f839f4b950c9c27e6fe9870182422be 405 Gene3D G3DSA:1.10.45.10 371 403 1.6E-6 T 31-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 DFR85_03315 1f839f4b950c9c27e6fe9870182422be 405 Gene3D G3DSA:3.30.465.40 18 220 5.0E-22 T 31-10-2018 DFR85_03315 1f839f4b950c9c27e6fe9870182422be 405 Pfam PF01565 FAD binding domain 47 169 6.0E-22 T 31-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 DFR85_15550 22e417d9d9f6bbaaf5880bd53938829e 75 SUPERFAMILY SSF64307 6 75 2.35E-12 T 31-10-2018 IPR036868 TusA-like domain superfamily DFR85_15550 22e417d9d9f6bbaaf5880bd53938829e 75 Gene3D G3DSA:3.30.110.40 4 75 4.2E-8 T 31-10-2018 IPR036868 TusA-like domain superfamily DFR85_15550 22e417d9d9f6bbaaf5880bd53938829e 75 Pfam PF01206 Sulfurtransferase TusA 7 72 1.5E-10 T 31-10-2018 IPR001455 TusA-like domain DFR85_03000 9ecf33ee52717a74aa578309dbe92e43 238 SUPERFAMILY SSF49899 11 184 2.45E-33 T 31-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily DFR85_03000 9ecf33ee52717a74aa578309dbe92e43 238 Pfam PF01828 Peptidase A4 family 14 173 4.2E-21 T 31-10-2018 IPR000250 Peptidase G1 GO:0004190|GO:0006508 DFR85_03000 9ecf33ee52717a74aa578309dbe92e43 238 Gene3D G3DSA:2.60.120.700 11 195 2.1E-25 T 31-10-2018 IPR038656 Peptidase G1 superfamily DFR85_14385 e5043215ae97555bccb022ef40e39602 335 SUPERFAMILY SSF54593 11 240 3.56E-15 T 31-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DFR85_14385 e5043215ae97555bccb022ef40e39602 335 Gene3D G3DSA:3.10.180.10 3 134 4.3E-23 T 31-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DFR85_14385 e5043215ae97555bccb022ef40e39602 335 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 161 271 4.4E-10 T 31-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain DFR85_14385 e5043215ae97555bccb022ef40e39602 335 SUPERFAMILY SSF54593 154 311 6.97E-22 T 31-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DFR85_14385 e5043215ae97555bccb022ef40e39602 335 Gene3D G3DSA:3.10.180.10 151 334 1.6E-34 T 31-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DFR85_13450 0ae6939b4c9b02ec1c9c33dfcc44a1f0 478 Pfam PF00083 Sugar (and other) transporter 62 477 5.4E-43 T 31-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 DFR85_13450 0ae6939b4c9b02ec1c9c33dfcc44a1f0 478 ProSitePatterns PS00217 Sugar transport proteins signature 2. 151 176 - T 31-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DFR85_13450 0ae6939b4c9b02ec1c9c33dfcc44a1f0 478 SUPERFAMILY SSF103473 42 477 8.89E-65 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_13450 0ae6939b4c9b02ec1c9c33dfcc44a1f0 478 Gene3D G3DSA:1.20.1250.20 52 478 8.1E-71 T 31-10-2018 DFR85_12020 50d27d993c2432961ec1e7867b4b360e 321 Gene3D G3DSA:3.30.420.40 2 108 1.6E-54 T 31-10-2018 DFR85_12020 50d27d993c2432961ec1e7867b4b360e 321 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 5 261 8.5E-34 T 31-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 DFR85_12020 50d27d993c2432961ec1e7867b4b360e 321 SUPERFAMILY SSF53067 110 273 3.05E-32 T 31-10-2018 DFR85_12020 50d27d993c2432961ec1e7867b4b360e 321 Gene3D G3DSA:3.30.420.40 109 263 1.6E-54 T 31-10-2018 DFR85_12020 50d27d993c2432961ec1e7867b4b360e 321 SUPERFAMILY SSF53067 1 105 1.06E-13 T 31-10-2018 DFR85_07890 8f8f788f49e0790baa928abdfeb0bd59 252 Pfam PF09973 Predicted membrane protein (DUF2208) 12 238 5.9E-64 T 31-10-2018 IPR009198 Uncharacterised conserved protein UCP014484, transmembrane DFR85_08580 e42f447fc6a81d41d04a51178c10c9ab 520 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 13 29 - T 31-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 DFR85_08580 e42f447fc6a81d41d04a51178c10c9ab 520 TIGRFAM TIGR00977 citramal_synth: citramalate synthase 6 511 1.3E-178 T 31-10-2018 IPR005675 Citramalate synthase GO:0019752|GO:0046912 KEGG: 00290+2.3.1.182|KEGG: 00660+2.3.1.182|MetaCyc: PWY-5101 DFR85_08580 e42f447fc6a81d41d04a51178c10c9ab 520 SMART SM00917 376 509 8.6E-24 T 31-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 DFR85_08580 e42f447fc6a81d41d04a51178c10c9ab 520 Pfam PF00682 HMGL-like 6 253 1.0E-52 T 31-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 DFR85_08580 e42f447fc6a81d41d04a51178c10c9ab 520 Pfam PF08502 LeuA allosteric (dimerisation) domain 377 508 1.9E-22 T 31-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 DFR85_08580 e42f447fc6a81d41d04a51178c10c9ab 520 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 203 216 - T 31-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 DFR85_08580 e42f447fc6a81d41d04a51178c10c9ab 520 SUPERFAMILY SSF51569 5 295 1.63E-79 T 31-10-2018 DFR85_08580 e42f447fc6a81d41d04a51178c10c9ab 520 Gene3D G3DSA:3.20.20.70 4 283 3.1E-82 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_08580 e42f447fc6a81d41d04a51178c10c9ab 520 Gene3D G3DSA:1.10.238.260 286 387 4.7E-24 T 31-10-2018 DFR85_08580 e42f447fc6a81d41d04a51178c10c9ab 520 SUPERFAMILY SSF110921 419 506 3.53E-13 T 31-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 DFR85_09115 915d24515e511e9c663d9b26c3d956b0 348 Pfam PF03481 Putative GTP-binding controlling metal-binding 199 333 4.3E-21 T 31-10-2018 IPR005145 Putative GTP-binding controlling metal-binding domain DFR85_09115 915d24515e511e9c663d9b26c3d956b0 348 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 6 206 8.6E-64 T 31-10-2018 IPR006070 YrdC-like domain GO:0003725 DFR85_09115 915d24515e511e9c663d9b26c3d956b0 348 SUPERFAMILY SSF55821 2 210 8.85E-68 T 31-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily DFR85_09115 915d24515e511e9c663d9b26c3d956b0 348 Gene3D G3DSA:3.90.870.10 1 212 3.5E-86 T 31-10-2018 DFR85_09115 915d24515e511e9c663d9b26c3d956b0 348 PIRSF PIRSF004930 1 339 3.1E-127 T 31-10-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 DFR85_09115 915d24515e511e9c663d9b26c3d956b0 348 Pfam PF01300 Telomere recombination 21 196 1.3E-57 T 31-10-2018 IPR006070 YrdC-like domain GO:0003725 DFR85_09115 915d24515e511e9c663d9b26c3d956b0 348 Gene3D G3DSA:3.40.50.11030 213 348 3.3E-41 T 31-10-2018 IPR038385 Threonylcarbamoyl-AMP synthase, C-terminal domain superfamily DFR85_07995 b7cc998b9be2e69445d96528cf2d0cb3 256 SUPERFAMILY SSF53335 3 251 1.51E-69 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR85_07995 b7cc998b9be2e69445d96528cf2d0cb3 256 PIRSF PIRSF017269 1 256 8.9E-83 T 31-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 DFR85_07995 b7cc998b9be2e69445d96528cf2d0cb3 256 Pfam PF14801 tRNA methyltransferase complex GCD14 subunit N-term 3 47 6.6E-7 T 31-10-2018 DFR85_07995 b7cc998b9be2e69445d96528cf2d0cb3 256 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 57 233 2.8E-32 T 31-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 DFR85_07995 b7cc998b9be2e69445d96528cf2d0cb3 256 Gene3D G3DSA:3.40.50.150 64 255 5.0E-64 T 31-10-2018 DFR85_07995 b7cc998b9be2e69445d96528cf2d0cb3 256 Gene3D G3DSA:3.10.330.20 2 62 4.7E-17 T 31-10-2018 DFR85_05735 8dfd208496228fd342c05f398f9426bc 539 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 25 471 3.6E-69 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_05735 8dfd208496228fd342c05f398f9426bc 539 SUPERFAMILY SSF81442 25 495 2.62E-83 T 31-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_05735 8dfd208496228fd342c05f398f9426bc 539 Gene3D G3DSA:1.20.210.10 13 525 8.1E-78 T 31-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_01295 f0062b98a665030d2e4dc60a0bedc3c8 304 SUPERFAMILY SSF53590 3 302 7.06E-82 T 31-10-2018 IPR036452 Ribonucleoside hydrolase-like DFR85_01295 f0062b98a665030d2e4dc60a0bedc3c8 304 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 3 296 1.4E-71 T 31-10-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain DFR85_01295 f0062b98a665030d2e4dc60a0bedc3c8 304 ProSitePatterns PS01247 Inosine-uridine preferring nucleoside hydrolase family signature. 8 18 - T 31-10-2018 IPR015910 Inosine/uridine-preferring nucleoside hydrolase, conserved site GO:0016799 DFR85_01295 f0062b98a665030d2e4dc60a0bedc3c8 304 Gene3D G3DSA:3.90.245.10 2 304 1.5E-104 T 31-10-2018 IPR036452 Ribonucleoside hydrolase-like DFR85_11885 39b56e1a2c2493e18caa75f509562bfa 233 Pfam PF00641 Zn-finger in Ran binding protein and others 3 27 6.4E-7 T 31-10-2018 IPR001876 Zinc finger, RanBP2-type DFR85_11885 39b56e1a2c2493e18caa75f509562bfa 233 Pfam PF00498 FHA domain 156 223 9.2E-17 T 31-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 DFR85_11885 39b56e1a2c2493e18caa75f509562bfa 233 Gene3D G3DSA:2.60.200.20 124 233 2.9E-31 T 31-10-2018 DFR85_11885 39b56e1a2c2493e18caa75f509562bfa 233 SMART SM00240 154 204 2.6E-12 T 31-10-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 DFR85_11885 39b56e1a2c2493e18caa75f509562bfa 233 Gene3D G3DSA:4.10.1060.10 1 34 2.5E-7 T 31-10-2018 DFR85_11885 39b56e1a2c2493e18caa75f509562bfa 233 ProSitePatterns PS01358 Zinc finger RanBP2-type signature. 3 22 - T 31-10-2018 IPR001876 Zinc finger, RanBP2-type DFR85_11885 39b56e1a2c2493e18caa75f509562bfa 233 SMART SM00547 1 25 0.0087 T 31-10-2018 IPR001876 Zinc finger, RanBP2-type DFR85_11885 39b56e1a2c2493e18caa75f509562bfa 233 SUPERFAMILY SSF49879 89 230 3.63E-21 T 31-10-2018 IPR008984 SMAD/FHA domain superfamily GO:0005515 DFR85_14790 e1cdb0c6e5440de44f72fc12a691e99a 532 Pfam PF13360 PQQ-like domain 377 445 2.8E-4 T 31-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat DFR85_14790 e1cdb0c6e5440de44f72fc12a691e99a 532 Pfam PF13360 PQQ-like domain 164 342 3.1E-14 T 31-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat DFR85_14790 e1cdb0c6e5440de44f72fc12a691e99a 532 Gene3D G3DSA:2.130.10.10 302 525 1.6E-20 T 31-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 DFR85_14790 e1cdb0c6e5440de44f72fc12a691e99a 532 SMART SM00564 147 181 8.4 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DFR85_14790 e1cdb0c6e5440de44f72fc12a691e99a 532 SMART SM00564 255 287 6.8 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DFR85_14790 e1cdb0c6e5440de44f72fc12a691e99a 532 SMART SM00564 370 397 140.0 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DFR85_14790 e1cdb0c6e5440de44f72fc12a691e99a 532 SMART SM00564 461 492 340.0 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DFR85_14790 e1cdb0c6e5440de44f72fc12a691e99a 532 SMART SM00564 300 339 45.0 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DFR85_14790 e1cdb0c6e5440de44f72fc12a691e99a 532 SMART SM00564 190 247 10.0 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DFR85_14790 e1cdb0c6e5440de44f72fc12a691e99a 532 SMART SM00564 404 444 130.0 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DFR85_14790 e1cdb0c6e5440de44f72fc12a691e99a 532 Gene3D G3DSA:2.40.128.630 206 289 2.8E-11 T 31-10-2018 DFR85_14790 e1cdb0c6e5440de44f72fc12a691e99a 532 SUPERFAMILY SSF50998 187 521 7.5E-29 T 31-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily DFR85_02735 feacac5b51a4b42d303252eba2c4bd4c 133 Gene3D G3DSA:3.40.50.1010 5 126 7.0E-12 T 31-10-2018 DFR85_02735 feacac5b51a4b42d303252eba2c4bd4c 133 SUPERFAMILY SSF88723 4 126 6.17E-17 T 31-10-2018 IPR029060 PIN-like domain superfamily DFR85_02735 feacac5b51a4b42d303252eba2c4bd4c 133 Pfam PF01850 PIN domain 5 123 8.6E-16 T 31-10-2018 IPR002716 PIN domain DFR85_00855 58bc273d5824051f422a2b6f44b23e10 170 Gene3D G3DSA:1.10.150.120 85 168 1.3E-37 T 31-10-2018 DFR85_00855 58bc273d5824051f422a2b6f44b23e10 170 SUPERFAMILY SSF47741 92 165 2.09E-36 T 31-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily DFR85_00855 58bc273d5824051f422a2b6f44b23e10 170 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 15 67 3.4E-6 T 31-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 DFR85_00855 58bc273d5824051f422a2b6f44b23e10 170 Pfam PF01799 [2Fe-2S] binding domain 81 154 2.5E-34 T 31-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 DFR85_00855 58bc273d5824051f422a2b6f44b23e10 170 SUPERFAMILY SSF54292 8 95 1.84E-22 T 31-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 DFR85_00855 58bc273d5824051f422a2b6f44b23e10 170 Gene3D G3DSA:3.10.20.30 1 84 1.0E-31 T 31-10-2018 IPR012675 Beta-grasp domain superfamily DFR85_13350 8aebadd1c356051983838f587dd88a32 300 Pfam PF01609 Transposase DDE domain 107 280 7.2E-13 T 31-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 DFR85_10735 fa5395aac2d3bec955d3382af6c4b11f 630 Gene3D G3DSA:1.10.10.410 569 628 2.3E-10 T 31-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal DFR85_10735 fa5395aac2d3bec955d3382af6c4b11f 630 SMART SM00845 486 627 7.7E-27 T 31-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 DFR85_10735 fa5395aac2d3bec955d3382af6c4b11f 630 Pfam PF02934 GatB/GatE catalytic domain 12 449 4.2E-72 T 31-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 DFR85_10735 fa5395aac2d3bec955d3382af6c4b11f 630 Gene3D G3DSA:3.30.1360.30 273 407 6.0E-44 T 31-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 DFR85_10735 fa5395aac2d3bec955d3382af6c4b11f 630 SUPERFAMILY SSF55261 283 407 6.54E-44 T 31-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 DFR85_10735 fa5395aac2d3bec955d3382af6c4b11f 630 ProDom PD609240 SUBUNIT E AMIDOTRANSFERASE 6.3.5.- LIGASE GLUTAMYL-TRNAGLN GLU-ADT BIOSYNTHESIS TRANSFERASE B 286 409 6.0E-46 T 31-10-2018 DFR85_10735 fa5395aac2d3bec955d3382af6c4b11f 630 Pfam PF02938 GAD domain 301 389 2.5E-13 T 31-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 DFR85_10735 fa5395aac2d3bec955d3382af6c4b11f 630 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 177 191 - T 31-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 DFR85_10735 fa5395aac2d3bec955d3382af6c4b11f 630 Hamap MF_00588 Glutamyl-tRNA(Gln) amidotransferase subunit E [gatE]. 1 630 290.79 T 31-10-2018 IPR004414 Glutamyl-tRNA(Gln) amidotransferase subunit E GO:0016884 DFR85_10735 fa5395aac2d3bec955d3382af6c4b11f 630 Gene3D G3DSA:1.10.150.380 456 552 2.6E-14 T 31-10-2018 DFR85_10735 fa5395aac2d3bec955d3382af6c4b11f 630 Pfam PF02637 GatB domain 486 627 5.6E-25 T 31-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 DFR85_10735 fa5395aac2d3bec955d3382af6c4b11f 630 TIGRFAM TIGR00134 gatE_arch: glutamyl-tRNA(Gln) amidotransferase, subunit E 4 628 6.2E-215 T 31-10-2018 IPR004414 Glutamyl-tRNA(Gln) amidotransferase subunit E GO:0016884 DFR85_10735 fa5395aac2d3bec955d3382af6c4b11f 630 SUPERFAMILY SSF89095 484 627 1.44E-19 T 31-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 DFR85_10735 fa5395aac2d3bec955d3382af6c4b11f 630 SUPERFAMILY SSF55931 2 456 1.44E-101 T 31-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 DFR85_10230 ebe91abd384678e3704dc91090269919 430 SUPERFAMILY SSF53383 16 410 5.9E-122 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase DFR85_10230 ebe91abd384678e3704dc91090269919 430 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 3 411 38.407 T 31-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 DFR85_10230 ebe91abd384678e3704dc91090269919 430 Gene3D G3DSA:3.90.1150.10 277 425 3.5E-49 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 DFR85_10230 ebe91abd384678e3704dc91090269919 430 PIRSF PIRSF000412 1 421 6.2E-136 T 31-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 DFR85_10230 ebe91abd384678e3704dc91090269919 430 Pfam PF00464 Serine hydroxymethyltransferase 9 384 2.0E-68 T 31-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 DFR85_10230 ebe91abd384678e3704dc91090269919 430 Gene3D G3DSA:3.40.640.10 39 276 2.1E-71 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR85_12240 778fcedfc9f33f2f9296e1cd717a5f36 111 Pfam PF05942 Archaeal PaREP1/PaREP8 family 2 106 7.4E-27 T 31-10-2018 IPR010268 Archaeal PaREP1 DFR85_12240 778fcedfc9f33f2f9296e1cd717a5f36 111 Gene3D G3DSA:1.20.120.330 1 111 6.3E-38 T 31-10-2018 DFR85_01905 479176144debf1a9ebab57b55497c6f8 350 Gene3D G3DSA:3.40.800.20 2 344 5.0E-98 T 31-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 DFR85_01905 479176144debf1a9ebab57b55497c6f8 350 PRINTS PR01271 Histone deacetylase signature 56 74 7.3E-6 T 31-10-2018 IPR003084 Histone deacetylase GO:0004407|GO:0016575 Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862|Reactome: R-HSA-3214815 DFR85_01905 479176144debf1a9ebab57b55497c6f8 350 PRINTS PR01271 Histone deacetylase signature 216 234 7.3E-6 T 31-10-2018 IPR003084 Histone deacetylase GO:0004407|GO:0016575 Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862|Reactome: R-HSA-3214815 DFR85_01905 479176144debf1a9ebab57b55497c6f8 350 PRINTS PR01271 Histone deacetylase signature 199 212 7.3E-6 T 31-10-2018 IPR003084 Histone deacetylase GO:0004407|GO:0016575 Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862|Reactome: R-HSA-3214815 DFR85_01905 479176144debf1a9ebab57b55497c6f8 350 PRINTS PR01271 Histone deacetylase signature 23 40 7.3E-6 T 31-10-2018 IPR003084 Histone deacetylase GO:0004407|GO:0016575 Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862|Reactome: R-HSA-3214815 DFR85_01905 479176144debf1a9ebab57b55497c6f8 350 SUPERFAMILY SSF52768 3 323 4.56E-97 T 31-10-2018 IPR023696 Ureohydrolase domain superfamily DFR85_01905 479176144debf1a9ebab57b55497c6f8 350 Pfam PF00850 Histone deacetylase domain 21 306 2.8E-76 T 31-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 DFR85_01905 479176144debf1a9ebab57b55497c6f8 350 PRINTS PR01270 Histone deacetylase superfamily signature 238 248 1.9E-16 T 31-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 DFR85_01905 479176144debf1a9ebab57b55497c6f8 350 PRINTS PR01270 Histone deacetylase superfamily signature 152 167 1.9E-16 T 31-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 DFR85_01905 479176144debf1a9ebab57b55497c6f8 350 PRINTS PR01270 Histone deacetylase superfamily signature 120 143 1.9E-16 T 31-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 DFR85_04125 4693ed18f9fc322f7fb1d680128fe58f 344 Pfam PF05913 Bacterial protein of unknown function (DUF871) 13 338 9.3E-78 T 31-10-2018 IPR008589 Protein of unknown function DUF871, prokaryotic DFR85_04125 4693ed18f9fc322f7fb1d680128fe58f 344 Gene3D G3DSA:3.20.20.70 4 229 5.7E-56 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_04125 4693ed18f9fc322f7fb1d680128fe58f 344 SUPERFAMILY SSF51445 8 228 9.9E-57 T 31-10-2018 IPR017853 Glycoside hydrolase superfamily DFR85_04125 4693ed18f9fc322f7fb1d680128fe58f 344 Gene3D G3DSA:2.40.100.10 248 343 3.5E-8 T 31-10-2018 IPR029000 Cyclophilin-like domain superfamily DFR85_04125 4693ed18f9fc322f7fb1d680128fe58f 344 SUPERFAMILY SSF50891 234 338 2.2E-12 T 31-10-2018 IPR029000 Cyclophilin-like domain superfamily DFR85_14010 c5c5b56aa6453018c1ed10ee05ff2856 271 SUPERFAMILY SSF52540 15 228 1.12E-34 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_14010 c5c5b56aa6453018c1ed10ee05ff2856 271 Gene3D G3DSA:3.40.50.300 22 270 6.5E-48 T 31-10-2018 DFR85_14010 c5c5b56aa6453018c1ed10ee05ff2856 271 SMART SM00382 45 237 1.7E-6 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_14010 c5c5b56aa6453018c1ed10ee05ff2856 271 Pfam PF00005 ABC transporter 39 169 2.4E-18 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR85_00790 1f597e4b504601dc1b58b427316dc7cd 257 PRINTS PR00377 Inositol monophosphatase superfamily signature 78 94 6.9E-14 T 31-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 DFR85_00790 1f597e4b504601dc1b58b427316dc7cd 257 PRINTS PR00377 Inositol monophosphatase superfamily signature 35 55 6.9E-14 T 31-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 DFR85_00790 1f597e4b504601dc1b58b427316dc7cd 257 PRINTS PR00377 Inositol monophosphatase superfamily signature 57 73 6.9E-14 T 31-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 DFR85_00790 1f597e4b504601dc1b58b427316dc7cd 257 PRINTS PR00377 Inositol monophosphatase superfamily signature 170 191 6.9E-14 T 31-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 DFR85_00790 1f597e4b504601dc1b58b427316dc7cd 257 Gene3D G3DSA:3.40.190.80 143 218 5.7E-9 T 31-10-2018 DFR85_00790 1f597e4b504601dc1b58b427316dc7cd 257 Pfam PF00459 Inositol monophosphatase family 25 210 3.0E-22 T 31-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 DFR85_00790 1f597e4b504601dc1b58b427316dc7cd 257 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 79 91 - T 31-10-2018 IPR020583 Inositol monophosphatase, metal-binding site DFR85_00790 1f597e4b504601dc1b58b427316dc7cd 257 SUPERFAMILY SSF56655 4 242 2.88E-38 T 31-10-2018 DFR85_00790 1f597e4b504601dc1b58b427316dc7cd 257 Gene3D G3DSA:3.30.540.10 1 139 1.2E-27 T 31-10-2018 DFR85_07120 7ab423c627f4baa3766e750fc65e2849 336 SMART SM01329 4 331 6.4E-152 T 31-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 DFR85_07120 7ab423c627f4baa3766e750fc65e2849 336 TIGRFAM TIGR02088 LEU3_arch: isopropylmalate/isohomocitrate dehydrogenases 5 331 3.1E-133 T 31-10-2018 IPR011828 Isopropylmalate/isohomocitrate dehydrogenase GO:0003862|GO:0009098|GO:0051287|GO:0055114 DFR85_07120 7ab423c627f4baa3766e750fc65e2849 336 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 220 239 - T 31-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 DFR85_07120 7ab423c627f4baa3766e750fc65e2849 336 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 5 327 5.3E-95 T 31-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 DFR85_07120 7ab423c627f4baa3766e750fc65e2849 336 SUPERFAMILY SSF53659 2 335 4.03E-110 T 31-10-2018 DFR85_07120 7ab423c627f4baa3766e750fc65e2849 336 Gene3D G3DSA:3.40.718.10 3 336 4.4E-134 T 31-10-2018 DFR85_08030 2638a605f8e5bfe75bea6c8657aa48e1 331 Hamap MF_01446 tRNA N6-adenosine threonylcarbamoyltransferase [kae1]. 1 330 35.672 T 31-10-2018 IPR034680 tRNA N6-adenosine threonylcarbamoyltransferase Kae1/OSGEP GO:0000408|GO:0002949 Reactome: R-HSA-6782315 DFR85_08030 2638a605f8e5bfe75bea6c8657aa48e1 331 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 296 3.6E-74 T 31-10-2018 IPR017861 Kae1/TsaD family DFR85_08030 2638a605f8e5bfe75bea6c8657aa48e1 331 Gene3D G3DSA:3.30.420.40 125 283 6.0E-83 T 31-10-2018 DFR85_08030 2638a605f8e5bfe75bea6c8657aa48e1 331 Gene3D G3DSA:3.30.420.40 3 305 6.0E-83 T 31-10-2018 DFR85_08030 2638a605f8e5bfe75bea6c8657aa48e1 331 Pfam PF00814 Glycoprotease family 26 297 9.8E-73 T 31-10-2018 IPR000905 Gcp-like domain DFR85_08030 2638a605f8e5bfe75bea6c8657aa48e1 331 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 149 170 1.2E-32 T 31-10-2018 IPR017861 Kae1/TsaD family DFR85_08030 2638a605f8e5bfe75bea6c8657aa48e1 331 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 95 114 1.2E-32 T 31-10-2018 IPR017861 Kae1/TsaD family DFR85_08030 2638a605f8e5bfe75bea6c8657aa48e1 331 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 1.2E-32 T 31-10-2018 IPR017861 Kae1/TsaD family DFR85_08030 2638a605f8e5bfe75bea6c8657aa48e1 331 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 253 262 1.2E-32 T 31-10-2018 IPR017861 Kae1/TsaD family DFR85_08030 2638a605f8e5bfe75bea6c8657aa48e1 331 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 127 139 1.2E-32 T 31-10-2018 IPR017861 Kae1/TsaD family DFR85_08030 2638a605f8e5bfe75bea6c8657aa48e1 331 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 74 94 1.2E-32 T 31-10-2018 IPR017861 Kae1/TsaD family DFR85_08030 2638a605f8e5bfe75bea6c8657aa48e1 331 TIGRFAM TIGR03722 arch_KAE1: universal archaeal protein Kae1 4 329 2.7E-140 T 31-10-2018 IPR022449 tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaea GO:0000408|GO:0002949 DFR85_08030 2638a605f8e5bfe75bea6c8657aa48e1 331 SUPERFAMILY SSF53067 1 299 3.45E-27 T 31-10-2018 DFR85_11770 9df1de6c67ce183161eb31a1ee175f50 255 Gene3D G3DSA:3.60.15.10 1 255 8.5E-76 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR85_11770 9df1de6c67ce183161eb31a1ee175f50 255 SMART SM00849 19 202 1.0E-32 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR85_11770 9df1de6c67ce183161eb31a1ee175f50 255 Pfam PF00753 Metallo-beta-lactamase superfamily 20 202 5.3E-23 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR85_11770 9df1de6c67ce183161eb31a1ee175f50 255 SUPERFAMILY SSF56281 9 219 3.93E-39 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR85_15155 ae0f61fe668e2f9e8ccc1c8f45a9734d 342 Pfam PF00107 Zinc-binding dehydrogenase 180 304 2.6E-27 T 31-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DFR85_15155 ae0f61fe668e2f9e8ccc1c8f45a9734d 342 Gene3D G3DSA:3.90.180.10 14 334 1.5E-110 T 31-10-2018 DFR85_15155 ae0f61fe668e2f9e8ccc1c8f45a9734d 342 SUPERFAMILY SSF51735 141 311 3.57E-39 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_15155 ae0f61fe668e2f9e8ccc1c8f45a9734d 342 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 136 1.6E-29 T 31-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DFR85_15155 ae0f61fe668e2f9e8ccc1c8f45a9734d 342 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 63 77 - T 31-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 DFR85_15155 ae0f61fe668e2f9e8ccc1c8f45a9734d 342 SUPERFAMILY SSF50129 2 174 6.13E-51 T 31-10-2018 IPR011032 GroES-like superfamily DFR85_15155 ae0f61fe668e2f9e8ccc1c8f45a9734d 342 SMART SM00829 8 340 8.9E-5 T 31-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DFR85_15155 ae0f61fe668e2f9e8ccc1c8f45a9734d 342 Gene3D G3DSA:3.40.50.720 152 291 1.5E-110 T 31-10-2018 DFR85_01120 db5f1ffa5eeed515546b0102cc90a0a6 448 Gene3D G3DSA:3.20.110.20 30 347 1.3E-28 T 31-10-2018 DFR85_01120 db5f1ffa5eeed515546b0102cc90a0a6 448 Pfam PF03065 Glycosyl hydrolase family 57 9 323 7.8E-72 T 31-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 DFR85_01120 db5f1ffa5eeed515546b0102cc90a0a6 448 SUPERFAMILY SSF88713 9 320 1.13E-60 T 31-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 DFR85_07845 c5cfc350d58e8bd7bf3bb6899664f24f 550 Gene3D G3DSA:3.40.50.300 225 507 2.7E-31 T 31-10-2018 DFR85_07845 c5cfc350d58e8bd7bf3bb6899664f24f 550 Pfam PF01935 Domain of unknown function DUF87 206 422 1.3E-11 T 31-10-2018 IPR002789 Helicase HerA, central domain DFR85_07845 c5cfc350d58e8bd7bf3bb6899664f24f 550 Gene3D G3DSA:1.10.8.730 288 401 2.7E-31 T 31-10-2018 DFR85_07845 c5cfc350d58e8bd7bf3bb6899664f24f 550 SUPERFAMILY SSF52540 222 517 2.63E-25 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_01855 2210bf316385be3ba56df6897b8ecc19 149 Pfam PF03551 Transcriptional regulator PadR-like family 17 84 9.5E-18 T 31-10-2018 IPR005149 Transcription regulator PadR, N-terminal DFR85_01855 2210bf316385be3ba56df6897b8ecc19 149 Gene3D G3DSA:1.10.10.10 2 108 3.3E-24 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_01855 2210bf316385be3ba56df6897b8ecc19 149 SUPERFAMILY SSF46785 7 97 1.86E-24 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_08705 b5e0c490025f23f0cd2f141fc65724f9 544 SUPERFAMILY SSF46955 14 71 5.31E-5 T 31-10-2018 IPR009061 Putative DNA-binding domain superfamily DFR85_08705 b5e0c490025f23f0cd2f141fc65724f9 544 Pfam PF03484 tRNA synthetase B5 domain 278 342 2.1E-13 T 31-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 DFR85_08705 b5e0c490025f23f0cd2f141fc65724f9 544 Pfam PF03483 B3/4 domain 92 234 1.1E-11 T 31-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 DFR85_08705 b5e0c490025f23f0cd2f141fc65724f9 544 Gene3D G3DSA:3.30.56.10 3 72 1.9E-12 T 31-10-2018 DFR85_08705 b5e0c490025f23f0cd2f141fc65724f9 544 SMART SM00874 275 342 1.5E-19 T 31-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 DFR85_08705 b5e0c490025f23f0cd2f141fc65724f9 544 Hamap MF_00284 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 538 30.746 T 31-10-2018 IPR022918 Phenylalanine-tRNA ligase beta chain 2, bacterial/archaeal GO:0004826 KEGG: 00970+6.1.1.20 DFR85_08705 b5e0c490025f23f0cd2f141fc65724f9 544 TIGRFAM TIGR00471 pheT_arch: phenylalanine--tRNA ligase, beta subunit 1 539 1.6E-134 T 31-10-2018 IPR004531 Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 DFR85_08705 b5e0c490025f23f0cd2f141fc65724f9 544 SMART SM00873 91 250 8.1E-13 T 31-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 DFR85_08705 b5e0c490025f23f0cd2f141fc65724f9 544 SUPERFAMILY SSF46955 275 345 1.37E-14 T 31-10-2018 IPR009061 Putative DNA-binding domain superfamily DFR85_08705 b5e0c490025f23f0cd2f141fc65724f9 544 Gene3D G3DSA:3.30.56.10 275 342 1.4E-17 T 31-10-2018 DFR85_08705 b5e0c490025f23f0cd2f141fc65724f9 544 Gene3D G3DSA:3.30.930.10 358 542 8.5E-35 T 31-10-2018 DFR85_08705 b5e0c490025f23f0cd2f141fc65724f9 544 SUPERFAMILY SSF55681 340 541 6.96E-32 T 31-10-2018 DFR85_08705 b5e0c490025f23f0cd2f141fc65724f9 544 Gene3D G3DSA:3.50.40.10 74 268 1.9E-56 T 31-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 DFR85_13210 7209734a0701c78a72be74d065d52f5c 412 Pfam PF01564 Spermine/spermidine synthase domain 55 229 9.4E-41 T 31-10-2018 DFR85_13210 7209734a0701c78a72be74d065d52f5c 412 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 75 88 - T 31-10-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 DFR85_13210 7209734a0701c78a72be74d065d52f5c 412 Gene3D G3DSA:3.40.50.150 50 274 2.1E-59 T 31-10-2018 DFR85_13210 7209734a0701c78a72be74d065d52f5c 412 SUPERFAMILY SSF53335 35 245 3.49E-53 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR85_13210 7209734a0701c78a72be74d065d52f5c 412 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 1 255 25.598 T 31-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 DFR85_12110 fbe21d2b7c5c94f63947aefe56d3af29 323 Pfam PF01905 CRISPR-associated negative auto-regulator DevR/Csa2 5 273 5.2E-76 T 31-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR DFR85_12110 fbe21d2b7c5c94f63947aefe56d3af29 323 TIGRFAM TIGR02583 DevR_archaea: CRISPR-associated protein Cas7/Csa2, subtype I-A/APERN 1 282 1.2E-93 T 31-10-2018 IPR002764 CRISPR-associated protein Cas7/Cst2/DevR, subtype I-a/Apern DFR85_12110 fbe21d2b7c5c94f63947aefe56d3af29 323 TIGRFAM TIGR01875 cas_MJ0381: CRISPR-associated autoregulator DevR family 5 259 4.5E-43 T 31-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR DFR85_06970 b88bd8d3e328a536d508fe5f2a68e09c 177 Hamap MF_00239 Cytidylate kinase [cmk]. 1 174 42.321 T 31-10-2018 IPR011892 Cytidylate kinase, putative GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 DFR85_06970 b88bd8d3e328a536d508fe5f2a68e09c 177 Pfam PF13189 Cytidylate kinase-like family 2 155 3.6E-18 T 31-10-2018 DFR85_06970 b88bd8d3e328a536d508fe5f2a68e09c 177 SUPERFAMILY SSF52540 1 172 1.01E-25 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_06970 b88bd8d3e328a536d508fe5f2a68e09c 177 PRINTS PR01100 Shikimate kinase family signature 92 109 9.2E-5 T 31-10-2018 DFR85_06970 b88bd8d3e328a536d508fe5f2a68e09c 177 PRINTS PR01100 Shikimate kinase family signature 70 79 9.2E-5 T 31-10-2018 DFR85_06970 b88bd8d3e328a536d508fe5f2a68e09c 177 PRINTS PR01100 Shikimate kinase family signature 3 18 9.2E-5 T 31-10-2018 DFR85_06970 b88bd8d3e328a536d508fe5f2a68e09c 177 TIGRFAM TIGR02173 cyt_kin_arch: putative cytidylate kinase 1 170 1.6E-60 T 31-10-2018 IPR011892 Cytidylate kinase, putative GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 DFR85_06970 b88bd8d3e328a536d508fe5f2a68e09c 177 Gene3D G3DSA:3.40.50.300 1 176 6.1E-44 T 31-10-2018 DFR85_11280 c9a8cdb33f7ef20df4aa0f2194cbb12a 153 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 70 145 9.6E-25 T 31-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 DFR85_11280 c9a8cdb33f7ef20df4aa0f2194cbb12a 153 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 6 146 35.294 T 31-10-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 DFR85_11280 c9a8cdb33f7ef20df4aa0f2194cbb12a 153 SUPERFAMILY SSF46767 69 147 1.19E-23 T 31-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 DFR85_11280 c9a8cdb33f7ef20df4aa0f2194cbb12a 153 Gene3D G3DSA:3.30.160.70 1 67 1.9E-36 T 31-10-2018 DFR85_11280 c9a8cdb33f7ef20df4aa0f2194cbb12a 153 SUPERFAMILY SSF53155 4 67 1.88E-6 T 31-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 DFR85_11280 c9a8cdb33f7ef20df4aa0f2194cbb12a 153 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 71 147 8.6E-23 T 31-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 DFR85_11280 c9a8cdb33f7ef20df4aa0f2194cbb12a 153 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 117 123 - T 31-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 DFR85_11280 c9a8cdb33f7ef20df4aa0f2194cbb12a 153 Gene3D G3DSA:1.10.10.10 68 152 8.8E-30 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_12835 ff9e9c035be8171019e12a13bbc8f0e8 245 Gene3D G3DSA:3.30.1600.10 30 165 3.7E-84 T 31-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily DFR85_12835 ff9e9c035be8171019e12a13bbc8f0e8 245 Gene3D G3DSA:3.40.50.1220 12 235 3.7E-84 T 31-10-2018 DFR85_12835 ff9e9c035be8171019e12a13bbc8f0e8 245 Pfam PF02146 Sir2 family 21 193 4.8E-52 T 31-10-2018 IPR003000 Sirtuin family GO:0070403 DFR85_12835 ff9e9c035be8171019e12a13bbc8f0e8 245 SUPERFAMILY SSF52467 3 241 1.81E-83 T 31-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily DFR85_12835 ff9e9c035be8171019e12a13bbc8f0e8 245 Hamap MF_01968 NAD-dependent protein deacetylase [cobB]. 5 238 62.457 T 31-10-2018 IPR028628 Sirtuin, class U GO:0034979|GO:0051287 DFR85_02945 aedab9dd06635ad8a39480ee910416f5 459 SUPERFAMILY SSF102114 101 414 1.15E-28 T 31-10-2018 DFR85_02945 aedab9dd06635ad8a39480ee910416f5 459 Gene3D G3DSA:3.20.20.70 100 441 1.0E-42 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_02945 aedab9dd06635ad8a39480ee910416f5 459 Pfam PF13353 4Fe-4S single cluster domain 107 238 3.3E-8 T 31-10-2018 DFR85_02945 aedab9dd06635ad8a39480ee910416f5 459 Pfam PF04055 Radical SAM superfamily 106 252 8.6E-9 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR85_07585 f962b7a1321a31566b4f2af4a8fad763 280 SUPERFAMILY SSF54637 133 277 1.56E-32 T 31-10-2018 IPR029069 HotDog domain superfamily DFR85_07585 f962b7a1321a31566b4f2af4a8fad763 280 Pfam PF03061 Thioesterase superfamily 143 213 3.7E-13 T 31-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 DFR85_07585 f962b7a1321a31566b4f2af4a8fad763 280 SUPERFAMILY SSF54637 1 113 4.63E-15 T 31-10-2018 IPR029069 HotDog domain superfamily DFR85_07585 f962b7a1321a31566b4f2af4a8fad763 280 Gene3D G3DSA:3.10.129.10 127 279 5.4E-32 T 31-10-2018 DFR85_07585 f962b7a1321a31566b4f2af4a8fad763 280 Gene3D G3DSA:3.10.129.10 1 117 1.4E-16 T 31-10-2018 DFR85_00070 6fdd85dc77b429f0a29a13782cb1dcf8 184 Pfam PF12007 Protein of unknown function (DUF3501) 1 179 6.4E-53 T 31-10-2018 IPR021890 Protein of unknown function DUF3501 DFR85_14590 473d612b0541e15d55a6de7af3327426 253 SUPERFAMILY SSF53213 5 252 2.62E-59 T 31-10-2018 DFR85_14590 473d612b0541e15d55a6de7af3327426 253 PIRSF PIRSF006157 1 253 6.9E-64 T 31-10-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 DFR85_14590 473d612b0541e15d55a6de7af3327426 253 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 5 247 6.0E-46 T 31-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 DFR85_14590 473d612b0541e15d55a6de7af3327426 253 Gene3D G3DSA:3.40.830.10 1 252 1.1E-59 T 31-10-2018 DFR85_10550 35372ea6fa7f07cdcf57e25ddd172c92 401 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 235 248 - T 31-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 DFR85_10550 35372ea6fa7f07cdcf57e25ddd172c92 401 SUPERFAMILY SSF53383 24 393 6.05E-102 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase DFR85_10550 35372ea6fa7f07cdcf57e25ddd172c92 401 Gene3D G3DSA:3.40.640.10 64 285 7.9E-114 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR85_10550 35372ea6fa7f07cdcf57e25ddd172c92 401 Gene3D G3DSA:3.90.1150.10 28 387 7.9E-114 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 DFR85_10550 35372ea6fa7f07cdcf57e25ddd172c92 401 Pfam PF00155 Aminotransferase class I and II 33 387 1.2E-68 T 31-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 DFR85_12520 13e1117496436fd7f61a819ca8e1654e 508 Pfam PF13360 PQQ-like domain 286 421 9.9E-8 T 31-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat DFR85_12520 13e1117496436fd7f61a819ca8e1654e 508 Pfam PF13360 PQQ-like domain 118 262 3.7E-8 T 31-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat DFR85_12520 13e1117496436fd7f61a819ca8e1654e 508 SUPERFAMILY SSF50998 130 380 5.49E-25 T 31-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily DFR85_12520 13e1117496436fd7f61a819ca8e1654e 508 SMART SM00564 389 420 49.0 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DFR85_12520 13e1117496436fd7f61a819ca8e1654e 508 SMART SM00564 168 224 67.0 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DFR85_12520 13e1117496436fd7f61a819ca8e1654e 508 SMART SM00564 285 316 280.0 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DFR85_12520 13e1117496436fd7f61a819ca8e1654e 508 SMART SM00564 125 159 0.5 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DFR85_12520 13e1117496436fd7f61a819ca8e1654e 508 SMART SM00564 233 266 67.0 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DFR85_12520 13e1117496436fd7f61a819ca8e1654e 508 SUPERFAMILY SSF50998 360 498 1.44E-12 T 31-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily DFR85_12520 13e1117496436fd7f61a819ca8e1654e 508 Gene3D G3DSA:2.130.10.10 79 387 3.0E-28 T 31-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 DFR85_12520 13e1117496436fd7f61a819ca8e1654e 508 Gene3D G3DSA:2.40.128.630 388 507 5.6E-8 T 31-10-2018 DFR85_04045 a4da92b5740f9aa5ec04770490ce1d70 105 Gene3D G3DSA:1.10.10.10 42 105 1.1E-9 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_04045 a4da92b5740f9aa5ec04770490ce1d70 105 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 43 59 3.2E-5 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR85_04045 a4da92b5740f9aa5ec04770490ce1d70 105 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 69 88 3.2E-5 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR85_04045 a4da92b5740f9aa5ec04770490ce1d70 105 SUPERFAMILY SSF46785 42 104 1.23E-10 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_04045 a4da92b5740f9aa5ec04770490ce1d70 105 Pfam PF09339 IclR helix-turn-helix domain 50 88 4.8E-10 T 31-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 DFR85_09425 c4de09a3bcc89a673e6511376f3ad812 195 PIRSF PIRSF000495 1 195 1.4E-55 T 31-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 DFR85_09425 c4de09a3bcc89a673e6511376f3ad812 195 SUPERFAMILY SSF52317 3 193 3.4E-38 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like DFR85_09425 c4de09a3bcc89a673e6511376f3ad812 195 Pfam PF00117 Glutamine amidotransferase class-I 5 185 1.7E-18 T 31-10-2018 IPR017926 Glutamine amidotransferase DFR85_09425 c4de09a3bcc89a673e6511376f3ad812 195 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 4 191 1.5E-61 T 31-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 DFR85_09425 c4de09a3bcc89a673e6511376f3ad812 195 Gene3D G3DSA:3.40.50.880 1 195 5.4E-50 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like DFR85_04085 3d8733a08a2011011a7f023ab3f04ccb 472 SUPERFAMILY SSF52540 189 445 6.96E-18 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_04085 3d8733a08a2011011a7f023ab3f04ccb 472 Pfam PF13175 AAA ATPase domain 190 312 5.5E-9 T 31-10-2018 DFR85_04085 3d8733a08a2011011a7f023ab3f04ccb 472 Gene3D G3DSA:3.40.50.300 187 437 1.6E-13 T 31-10-2018 DFR85_10245 e65b654a8d76e0f386ec64b7555be88e 408 Gene3D G3DSA:3.40.50.1260 199 394 7.0E-114 T 31-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR85_10245 e65b654a8d76e0f386ec64b7555be88e 408 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 11 404 33.33 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR85_10245 e65b654a8d76e0f386ec64b7555be88e 408 PIRSF PIRSF000724 5 408 8.3E-124 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR85_10245 e65b654a8d76e0f386ec64b7555be88e 408 Gene3D G3DSA:3.40.50.1260 16 400 7.0E-114 T 31-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR85_10245 e65b654a8d76e0f386ec64b7555be88e 408 Pfam PF00162 Phosphoglycerate kinase 12 393 1.7E-100 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR85_10245 e65b654a8d76e0f386ec64b7555be88e 408 PRINTS PR00477 Phosphoglycerate kinase family signature 16 32 2.3E-56 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR85_10245 e65b654a8d76e0f386ec64b7555be88e 408 PRINTS PR00477 Phosphoglycerate kinase family signature 150 172 2.3E-56 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR85_10245 e65b654a8d76e0f386ec64b7555be88e 408 PRINTS PR00477 Phosphoglycerate kinase family signature 39 61 2.3E-56 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR85_10245 e65b654a8d76e0f386ec64b7555be88e 408 PRINTS PR00477 Phosphoglycerate kinase family signature 180 202 2.3E-56 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR85_10245 e65b654a8d76e0f386ec64b7555be88e 408 PRINTS PR00477 Phosphoglycerate kinase family signature 324 349 2.3E-56 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR85_10245 e65b654a8d76e0f386ec64b7555be88e 408 PRINTS PR00477 Phosphoglycerate kinase family signature 203 222 2.3E-56 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR85_10245 e65b654a8d76e0f386ec64b7555be88e 408 PRINTS PR00477 Phosphoglycerate kinase family signature 115 130 2.3E-56 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR85_10245 e65b654a8d76e0f386ec64b7555be88e 408 PRINTS PR00477 Phosphoglycerate kinase family signature 357 368 2.3E-56 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR85_10245 e65b654a8d76e0f386ec64b7555be88e 408 PRINTS PR00477 Phosphoglycerate kinase family signature 380 397 2.3E-56 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR85_10245 e65b654a8d76e0f386ec64b7555be88e 408 SUPERFAMILY SSF53748 9 403 3.77E-105 T 31-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR85_10945 78f8690e2c031e92d51e0e923fb56113 265 Pfam PF00106 short chain dehydrogenase 8 199 2.1E-36 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_10945 78f8690e2c031e92d51e0e923fb56113 265 Gene3D G3DSA:3.40.50.720 1 264 2.9E-51 T 31-10-2018 DFR85_10945 78f8690e2c031e92d51e0e923fb56113 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.1E-14 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_10945 78f8690e2c031e92d51e0e923fb56113 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.1E-14 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_10945 78f8690e2c031e92d51e0e923fb56113 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 244 1.1E-14 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_10945 78f8690e2c031e92d51e0e923fb56113 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 1.1E-14 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_10945 78f8690e2c031e92d51e0e923fb56113 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.1E-14 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_10945 78f8690e2c031e92d51e0e923fb56113 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.1E-14 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_10945 78f8690e2c031e92d51e0e923fb56113 265 SUPERFAMILY SSF51735 7 262 7.42E-56 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_12915 9a662343fc7cc0944b010ca4c3b9c4ab 363 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 46 351 2.1E-104 T 31-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 DFR85_12915 9a662343fc7cc0944b010ca4c3b9c4ab 363 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 15 361 36.066 T 31-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 DFR85_12915 9a662343fc7cc0944b010ca4c3b9c4ab 363 Gene3D G3DSA:3.40.50.10470 151 351 1.1E-99 T 31-10-2018 DFR85_12915 9a662343fc7cc0944b010ca4c3b9c4ab 363 SUPERFAMILY SSF100950 16 353 1.59E-103 T 31-10-2018 IPR037171 NagB/RpiA transferase-like DFR85_12915 9a662343fc7cc0944b010ca4c3b9c4ab 363 Gene3D G3DSA:1.20.120.420 50 150 1.1E-99 T 31-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 DFR85_12915 9a662343fc7cc0944b010ca4c3b9c4ab 363 Pfam PF01008 Initiation factor 2 subunit family 59 351 3.3E-73 T 31-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 DFR85_12915 9a662343fc7cc0944b010ca4c3b9c4ab 363 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 19 350 2.7E-107 T 31-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 DFR85_01235 26dfbdc6653a627eef5a4f5bd2a10ffd 182 Gene3D G3DSA:1.20.1260.10 2 129 2.0E-9 T 31-10-2018 IPR012347 Ferritin-like DFR85_01235 26dfbdc6653a627eef5a4f5bd2a10ffd 182 SUPERFAMILY SSF47240 123 179 1.62E-5 T 31-10-2018 IPR009078 Ferritin-like superfamily DFR85_01235 26dfbdc6653a627eef5a4f5bd2a10ffd 182 SUPERFAMILY SSF47240 1 128 1.25E-17 T 31-10-2018 IPR009078 Ferritin-like superfamily DFR85_00585 43afdf7c1b5ee21c6fc8099633c3f1c7 487 SUPERFAMILY SSF52518 16 163 2.01E-25 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR85_00585 43afdf7c1b5ee21c6fc8099633c3f1c7 487 Gene3D G3DSA:3.40.50.970 343 487 1.8E-20 T 31-10-2018 DFR85_00585 43afdf7c1b5ee21c6fc8099633c3f1c7 487 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 16 164 7.5E-28 T 31-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 DFR85_00585 43afdf7c1b5ee21c6fc8099633c3f1c7 487 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 184 293 1.2E-13 T 31-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 DFR85_00585 43afdf7c1b5ee21c6fc8099633c3f1c7 487 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 368 477 2.3E-15 T 31-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 DFR85_00585 43afdf7c1b5ee21c6fc8099633c3f1c7 487 Gene3D G3DSA:3.40.50.970 11 170 8.6E-36 T 31-10-2018 DFR85_00585 43afdf7c1b5ee21c6fc8099633c3f1c7 487 Gene3D G3DSA:3.40.50.1220 177 319 1.4E-14 T 31-10-2018 DFR85_00585 43afdf7c1b5ee21c6fc8099633c3f1c7 487 SUPERFAMILY SSF52518 364 478 4.42E-19 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR85_00585 43afdf7c1b5ee21c6fc8099633c3f1c7 487 SUPERFAMILY SSF52467 180 319 9.12E-16 T 31-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily DFR85_02860 d29403d3ea870fdb80983f650e242195 278 Gene3D G3DSA:3.60.110.10 1 274 1.8E-81 T 31-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily DFR85_02860 d29403d3ea870fdb80983f650e242195 278 SUPERFAMILY SSF56317 2 263 9.42E-67 T 31-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily DFR85_02860 d29403d3ea870fdb80983f650e242195 278 Pfam PF00795 Carbon-nitrogen hydrolase 3 253 1.8E-50 T 31-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 DFR85_01730 d97491237b16322ea854be15c474dba5 238 Gene3D G3DSA:3.40.50.720 1 238 1.9E-43 T 31-10-2018 DFR85_01730 d97491237b16322ea854be15c474dba5 238 SUPERFAMILY SSF51735 4 236 4.97E-42 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_01730 d97491237b16322ea854be15c474dba5 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 3.6E-8 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_01730 d97491237b16322ea854be15c474dba5 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 3.6E-8 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_01730 d97491237b16322ea854be15c474dba5 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 219 3.6E-8 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_01730 d97491237b16322ea854be15c474dba5 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 3.6E-8 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_01730 d97491237b16322ea854be15c474dba5 238 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 235 2.7E-29 T 31-10-2018 DFR85_01225 3e9b69214f7714bb50fc13fbc69df1bb 148 PIRSF PIRSF000239 1 147 1.3E-34 T 31-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 DFR85_01225 3e9b69214f7714bb50fc13fbc69df1bb 148 SUPERFAMILY SSF52833 1 147 2.59E-50 T 31-10-2018 IPR036249 Thioredoxin-like superfamily DFR85_01225 3e9b69214f7714bb50fc13fbc69df1bb 148 Gene3D G3DSA:3.40.30.10 2 148 4.4E-47 T 31-10-2018 DFR85_01225 3e9b69214f7714bb50fc13fbc69df1bb 148 Pfam PF00578 AhpC/TSA family 6 126 4.7E-41 T 31-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 DFR85_14210 b3d4031f89283d83868e60c29133d167 154 SUPERFAMILY SSF53163 1 144 6.8E-5 T 31-10-2018 IPR023430 Peptidase HybD-like domain superfamily DFR85_14210 b3d4031f89283d83868e60c29133d167 154 Gene3D G3DSA:3.40.50.1450 1 147 4.8E-8 T 31-10-2018 IPR023430 Peptidase HybD-like domain superfamily DFR85_12970 6b84690015cd2fe2b2e2ca3413aeab20 414 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 1 53 3.5E-13 T 31-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_12970 6b84690015cd2fe2b2e2ca3413aeab20 414 SUPERFAMILY SSF53706 2 356 2.49E-118 T 31-10-2018 DFR85_12970 6b84690015cd2fe2b2e2ca3413aeab20 414 Gene3D G3DSA:2.20.25.90 1 53 2.4E-12 T 31-10-2018 DFR85_12970 6b84690015cd2fe2b2e2ca3413aeab20 414 Gene3D G3DSA:3.40.50.740 66 370 9.3E-89 T 31-10-2018 DFR85_12970 6b84690015cd2fe2b2e2ca3413aeab20 414 Gene3D G3DSA:3.40.228.10 133 329 9.3E-89 T 31-10-2018 DFR85_12970 6b84690015cd2fe2b2e2ca3413aeab20 414 SMART SM00926 1 54 8.3E-17 T 31-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_12970 6b84690015cd2fe2b2e2ca3413aeab20 414 Pfam PF00384 Molybdopterin oxidoreductase 57 354 5.6E-44 T 31-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_12670 41ba717ad4dff2bbd09efa06f4a39cb9 387 Gene3D G3DSA:3.30.390.10 8 366 1.7E-124 T 31-10-2018 IPR029017 Enolase-like, N-terminal DFR85_12670 41ba717ad4dff2bbd09efa06f4a39cb9 387 Pfam PF13378 Enolase C-terminal domain-like 137 357 5.6E-58 T 31-10-2018 IPR029065 Enolase C-terminal domain-like DFR85_12670 41ba717ad4dff2bbd09efa06f4a39cb9 387 SUPERFAMILY SSF54826 4 116 2.89E-28 T 31-10-2018 DFR85_12670 41ba717ad4dff2bbd09efa06f4a39cb9 387 SMART SM00922 133 238 4.0E-20 T 31-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal DFR85_12670 41ba717ad4dff2bbd09efa06f4a39cb9 387 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 188 219 - T 31-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 DFR85_12670 41ba717ad4dff2bbd09efa06f4a39cb9 387 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 20 112 3.8E-20 T 31-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain DFR85_12670 41ba717ad4dff2bbd09efa06f4a39cb9 387 Gene3D G3DSA:3.20.20.120 107 346 1.7E-124 T 31-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily DFR85_12670 41ba717ad4dff2bbd09efa06f4a39cb9 387 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 87 112 - T 31-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 DFR85_12670 41ba717ad4dff2bbd09efa06f4a39cb9 387 SUPERFAMILY SSF51604 100 365 3.28E-75 T 31-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily DFR85_12540 81471ff2d78415ef7f17b2b72edd7447 306 Pfam PF12367 Pyruvate ferredoxin oxidoreductase beta subunit C terminal 199 272 5.2E-19 T 31-10-2018 IPR032686 Pyruvate ferredoxin oxidoreductase beta subunit, C-terminal DFR85_12540 81471ff2d78415ef7f17b2b72edd7447 306 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 46 195 3.0E-27 T 31-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 DFR85_12540 81471ff2d78415ef7f17b2b72edd7447 306 TIGRFAM TIGR02177 PorB_KorB: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family 12 302 1.3E-126 T 31-10-2018 IPR011896 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate DFR85_12540 81471ff2d78415ef7f17b2b72edd7447 306 SUPERFAMILY SSF52518 11 290 5.44E-72 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR85_12540 81471ff2d78415ef7f17b2b72edd7447 306 Gene3D G3DSA:3.40.50.970 21 199 3.0E-21 T 31-10-2018 DFR85_15690 e725d9268b4c8c6762f8a130584fd58d 445 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 326 428 1.2E-25 T 31-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 DFR85_15690 e725d9268b4c8c6762f8a130584fd58d 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 122 140 6.4E-27 T 31-10-2018 DFR85_15690 e725d9268b4c8c6762f8a130584fd58d 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 6.4E-27 T 31-10-2018 DFR85_15690 e725d9268b4c8c6762f8a130584fd58d 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 243 259 6.4E-27 T 31-10-2018 DFR85_15690 e725d9268b4c8c6762f8a130584fd58d 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 271 293 6.4E-27 T 31-10-2018 DFR85_15690 e725d9268b4c8c6762f8a130584fd58d 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 161 179 6.4E-27 T 31-10-2018 DFR85_15690 e725d9268b4c8c6762f8a130584fd58d 445 Gene3D G3DSA:3.30.390.30 325 445 1.8E-33 T 31-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 DFR85_15690 e725d9268b4c8c6762f8a130584fd58d 445 Gene3D G3DSA:3.50.50.60 134 250 1.9E-100 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_15690 e725d9268b4c8c6762f8a130584fd58d 445 SUPERFAMILY SSF51905 3 345 1.83E-43 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_15690 e725d9268b4c8c6762f8a130584fd58d 445 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 36 46 - T 31-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 DFR85_15690 e725d9268b4c8c6762f8a130584fd58d 445 SUPERFAMILY SSF55424 322 443 6.01E-30 T 31-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 DFR85_15690 e725d9268b4c8c6762f8a130584fd58d 445 Gene3D G3DSA:3.50.50.60 6 310 1.9E-100 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_15690 e725d9268b4c8c6762f8a130584fd58d 445 TIGRFAM TIGR02053 MerA: mercury(II) reductase 4 445 1.7E-173 T 31-10-2018 IPR021179 Mercury(II) reductase GO:0016152|GO:0016491|GO:0045340|GO:0050660|GO:0050661|GO:0050787|GO:0055114 DFR85_15690 e725d9268b4c8c6762f8a130584fd58d 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 286 293 2.5E-60 T 31-10-2018 DFR85_15690 e725d9268b4c8c6762f8a130584fd58d 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 161 186 2.5E-60 T 31-10-2018 DFR85_15690 e725d9268b4c8c6762f8a130584fd58d 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 35 50 2.5E-60 T 31-10-2018 DFR85_15690 e725d9268b4c8c6762f8a130584fd58d 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 404 424 2.5E-60 T 31-10-2018 DFR85_15690 e725d9268b4c8c6762f8a130584fd58d 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 382 397 2.5E-60 T 31-10-2018 DFR85_15690 e725d9268b4c8c6762f8a130584fd58d 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 2.5E-60 T 31-10-2018 DFR85_15690 e725d9268b4c8c6762f8a130584fd58d 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 125 134 2.5E-60 T 31-10-2018 DFR85_15690 e725d9268b4c8c6762f8a130584fd58d 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 322 343 2.5E-60 T 31-10-2018 DFR85_15690 e725d9268b4c8c6762f8a130584fd58d 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 244 258 2.5E-60 T 31-10-2018 DFR85_15690 e725d9268b4c8c6762f8a130584fd58d 445 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 306 2.3E-55 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR85_15690 e725d9268b4c8c6762f8a130584fd58d 445 PIRSF PIRSF000350 1 445 2.2E-126 T 31-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 DFR85_00540 b692ce7f2867ecdfc386d52f9978a7db 485 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 5 483 1.4E-92 T 31-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 DFR85_00540 b692ce7f2867ecdfc386d52f9978a7db 485 SUPERFAMILY SSF55486 3 484 2.08E-103 T 31-10-2018 DFR85_00540 b692ce7f2867ecdfc386d52f9978a7db 485 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 285 301 3.4E-66 T 31-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 DFR85_00540 b692ce7f2867ecdfc386d52f9978a7db 485 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 221 237 3.4E-66 T 31-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 DFR85_00540 b692ce7f2867ecdfc386d52f9978a7db 485 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 371 388 3.4E-66 T 31-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 DFR85_00540 b692ce7f2867ecdfc386d52f9978a7db 485 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 394 415 3.4E-66 T 31-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 DFR85_00540 b692ce7f2867ecdfc386d52f9978a7db 485 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 258 277 3.4E-66 T 31-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 DFR85_00540 b692ce7f2867ecdfc386d52f9978a7db 485 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 140 160 3.4E-66 T 31-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 DFR85_00540 b692ce7f2867ecdfc386d52f9978a7db 485 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 325 344 3.4E-66 T 31-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 DFR85_00540 b692ce7f2867ecdfc386d52f9978a7db 485 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 238 257 3.4E-66 T 31-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 DFR85_00540 b692ce7f2867ecdfc386d52f9978a7db 485 Gene3D G3DSA:1.10.1370.30 1 484 9.3E-181 T 31-10-2018 DFR85_00540 b692ce7f2867ecdfc386d52f9978a7db 485 PIRSF PIRSF006615 1 485 2.2E-189 T 31-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 DFR85_02715 f3b78bb1f2b11fed97bdf449baf5aa94 488 Gene3D G3DSA:1.20.1740.10 15 439 3.1E-46 T 31-10-2018 DFR85_02715 f3b78bb1f2b11fed97bdf449baf5aa94 488 Pfam PF13520 Amino acid permease 21 436 1.3E-25 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_02715 f3b78bb1f2b11fed97bdf449baf5aa94 488 PIRSF PIRSF006060 8 481 1.5E-43 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_07975 64e5093ca13c481d17faa3d1dfe0ba6e 291 Pfam PF00795 Carbon-nitrogen hydrolase 10 209 4.4E-17 T 31-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 DFR85_07975 64e5093ca13c481d17faa3d1dfe0ba6e 291 Gene3D G3DSA:3.60.110.10 2 261 9.0E-30 T 31-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily DFR85_07975 64e5093ca13c481d17faa3d1dfe0ba6e 291 SUPERFAMILY SSF56317 8 243 3.4E-28 T 31-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily DFR85_12360 bc57de6360dd519924b7cbadb715602d 683 Gene3D G3DSA:3.40.50.300 2 183 1.7E-22 T 31-10-2018 DFR85_12360 bc57de6360dd519924b7cbadb715602d 683 Gene3D G3DSA:3.40.50.300 210 410 2.8E-27 T 31-10-2018 DFR85_12360 bc57de6360dd519924b7cbadb715602d 683 Pfam PF04851 Type III restriction enzyme, res subunit 17 162 6.2E-20 T 31-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 DFR85_12360 bc57de6360dd519924b7cbadb715602d 683 SMART SM00487 15 198 3.8E-13 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain DFR85_12360 bc57de6360dd519924b7cbadb715602d 683 Pfam PF00271 Helicase conserved C-terminal domain 283 393 2.6E-18 T 31-10-2018 IPR001650 Helicase, C-terminal DFR85_12360 bc57de6360dd519924b7cbadb715602d 683 SMART SM00490 310 394 1.2E-15 T 31-10-2018 IPR001650 Helicase, C-terminal DFR85_12360 bc57de6360dd519924b7cbadb715602d 683 SUPERFAMILY SSF52540 32 395 3.21E-36 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_12360 bc57de6360dd519924b7cbadb715602d 683 ProDom PD038969 NUCLEOTIDE-BINDING HELICASE ATP-BINDING HYDROLASE PLASMID HELICASE PH1064 MJECL01 ATP-DEPENDENT 509 672 1.0E-26 T 31-10-2018 DFR85_12070 e156c2dbf3d9e0e9dba9dc2908608734 301 PRINTS PR00069 Aldo-keto reductase signature 95 113 3.8E-18 T 31-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 DFR85_12070 e156c2dbf3d9e0e9dba9dc2908608734 301 PRINTS PR00069 Aldo-keto reductase signature 126 143 3.8E-18 T 31-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 DFR85_12070 e156c2dbf3d9e0e9dba9dc2908608734 301 PRINTS PR00069 Aldo-keto reductase signature 225 249 3.8E-18 T 31-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 DFR85_12070 e156c2dbf3d9e0e9dba9dc2908608734 301 PRINTS PR00069 Aldo-keto reductase signature 38 62 3.8E-18 T 31-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 DFR85_12070 e156c2dbf3d9e0e9dba9dc2908608734 301 Pfam PF00248 Aldo/keto reductase family 12 290 6.7E-69 T 31-10-2018 IPR023210 NADP-dependent oxidoreductase domain DFR85_12070 e156c2dbf3d9e0e9dba9dc2908608734 301 PIRSF PIRSF000097 5 121 2.8E-21 T 31-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 DFR85_12070 e156c2dbf3d9e0e9dba9dc2908608734 301 PIRSF PIRSF000097 114 299 6.5E-14 T 31-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 DFR85_12070 e156c2dbf3d9e0e9dba9dc2908608734 301 Gene3D G3DSA:3.20.20.100 1 298 9.8E-85 T 31-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily DFR85_12070 e156c2dbf3d9e0e9dba9dc2908608734 301 SUPERFAMILY SSF51430 3 292 3.93E-82 T 31-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily DFR85_12070 e156c2dbf3d9e0e9dba9dc2908608734 301 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 126 143 - T 31-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 DFR85_08865 5536d7527dcbe0a2d9bd508cc8477d99 134 SUPERFAMILY SSF111038 1 134 2.09E-41 T 31-10-2018 IPR035917 YjbQ-like superfamily DFR85_08865 5536d7527dcbe0a2d9bd508cc8477d99 134 Gene3D G3DSA:2.60.120.460 1 134 6.7E-53 T 31-10-2018 IPR035917 YjbQ-like superfamily DFR85_08865 5536d7527dcbe0a2d9bd508cc8477d99 134 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 7 134 1.9E-38 T 31-10-2018 IPR001602 Uncharacterised protein family UPF0047 DFR85_08865 5536d7527dcbe0a2d9bd508cc8477d99 134 ProSitePatterns PS01314 Uncharacterized protein family UPF0047 signature. 96 114 - T 31-10-2018 IPR001602 Uncharacterised protein family UPF0047 DFR85_08865 5536d7527dcbe0a2d9bd508cc8477d99 134 PIRSF PIRSF004681 1 134 3.4E-40 T 31-10-2018 IPR001602 Uncharacterised protein family UPF0047 DFR85_08865 5536d7527dcbe0a2d9bd508cc8477d99 134 Pfam PF01894 Uncharacterised protein family UPF0047 20 131 5.8E-38 T 31-10-2018 IPR001602 Uncharacterised protein family UPF0047 DFR85_08910 783e7bcc3acaee4368d5078f7eb37033 66 Pfam PF01194 RNA polymerases N / 8 kDa subunit 1 58 2.9E-30 T 31-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 DFR85_08910 783e7bcc3acaee4368d5078f7eb37033 66 SUPERFAMILY SSF46924 1 63 9.16E-28 T 31-10-2018 IPR023580 RNA polymerase subunit RPB10 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 DFR85_08910 783e7bcc3acaee4368d5078f7eb37033 66 Gene3D G3DSA:1.10.10.60 1 66 1.0E-33 T 31-10-2018 DFR85_08910 783e7bcc3acaee4368d5078f7eb37033 66 ProDom PD006539 RNA POLYMERASE DNA-DIRECTED SUBUNIT TRANSFERASE NUCLEOTIDYLTRANSFERASE METAL-BINDING ZINC TRANSCRIPTION N 10 49 6.0E-16 T 31-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 DFR85_08910 783e7bcc3acaee4368d5078f7eb37033 66 PIRSF PIRSF005653 1 66 1.8E-31 T 31-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 DFR85_08910 783e7bcc3acaee4368d5078f7eb37033 66 Hamap MF_00250 DNA-directed RNA polymerase subunit N [rpoN]. 1 63 22.949 T 31-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 DFR85_08910 783e7bcc3acaee4368d5078f7eb37033 66 ProSitePatterns PS01112 RNA polymerases N / 8 Kd subunits signature. 2 11 - T 31-10-2018 IPR020789 RNA polymerases, subunit N, zinc binding site GO:0003677|GO:0003899|GO:0006351|GO:0008270 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 DFR85_07820 b067b0549d80af5102c6fa4ac158331c 182 Gene3D G3DSA:3.40.50.150 3 182 1.5E-37 T 31-10-2018 DFR85_07820 b067b0549d80af5102c6fa4ac158331c 182 Pfam PF05175 Methyltransferase small domain 16 178 6.0E-35 T 31-10-2018 IPR007848 Methyltransferase small domain GO:0008168 DFR85_07820 b067b0549d80af5102c6fa4ac158331c 182 SUPERFAMILY SSF53335 17 179 4.22E-31 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR85_07350 14788462d54d1940380ce0de2ea42461 323 Pfam PF00145 C-5 cytosine-specific DNA methylase 5 311 1.5E-50 T 31-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 DFR85_07350 14788462d54d1940380ce0de2ea42461 323 Gene3D G3DSA:3.40.50.150 7 309 6.2E-67 T 31-10-2018 DFR85_07350 14788462d54d1940380ce0de2ea42461 323 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 119 133 1.1E-12 T 31-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 DFR85_07350 14788462d54d1940380ce0de2ea42461 323 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 163 176 1.1E-12 T 31-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 DFR85_07350 14788462d54d1940380ce0de2ea42461 323 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 5 21 1.1E-12 T 31-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 DFR85_07350 14788462d54d1940380ce0de2ea42461 323 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 6 218 1.6E-34 T 31-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 DFR85_07350 14788462d54d1940380ce0de2ea42461 323 Gene3D G3DSA:3.90.120.10 158 302 6.2E-67 T 31-10-2018 DFR85_07350 14788462d54d1940380ce0de2ea42461 323 SUPERFAMILY SSF53335 3 312 1.02E-76 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR85_03310 ac6b7a8ae2d765c9595dd1973412a1e8 470 Pfam PF13520 Amino acid permease 29 445 5.8E-23 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_03310 ac6b7a8ae2d765c9595dd1973412a1e8 470 Gene3D G3DSA:1.20.1740.10 15 467 1.4E-30 T 31-10-2018 DFR85_03310 ac6b7a8ae2d765c9595dd1973412a1e8 470 PIRSF PIRSF006060 1 465 2.0E-56 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_10750 83c585f7015f1debe4b0cc3b22b6bec1 417 Gene3D G3DSA:1.10.287.660 140 252 3.3E-40 T 31-10-2018 IPR029012 Helix hairpin bin domain superfamily DFR85_10750 83c585f7015f1debe4b0cc3b22b6bec1 417 Gene3D G3DSA:3.30.420.220 1 107 7.0E-34 T 31-10-2018 DFR85_10750 83c585f7015f1debe4b0cc3b22b6bec1 417 Pfam PF01798 snoRNA binding domain, fibrillarin 147 372 3.9E-75 T 31-10-2018 IPR002687 Nop domain DFR85_10750 83c585f7015f1debe4b0cc3b22b6bec1 417 Gene3D G3DSA:1.10.246.90 253 377 3.4E-50 T 31-10-2018 DFR85_10750 83c585f7015f1debe4b0cc3b22b6bec1 417 SUPERFAMILY SSF89124 134 374 1.7E-80 T 31-10-2018 IPR036070 Nop domain superfamily DFR85_10750 83c585f7015f1debe4b0cc3b22b6bec1 417 Gene3D G3DSA:1.10.150.460 170 221 3.3E-40 T 31-10-2018 DFR85_10750 83c585f7015f1debe4b0cc3b22b6bec1 417 SMART SM00931 139 191 1.1E-25 T 31-10-2018 IPR012976 NOSIC DFR85_15060 f813b5cd9e5460999625921f9a508314 114 Pfam PF01906 Putative heavy-metal-binding 8 110 3.1E-36 T 31-10-2018 IPR002765 Uncharacterised protein family UPF0145 DFR85_15060 f813b5cd9e5460999625921f9a508314 114 Gene3D G3DSA:3.30.110.70 9 114 1.9E-29 T 31-10-2018 DFR85_15060 f813b5cd9e5460999625921f9a508314 114 SUPERFAMILY SSF117782 8 112 1.22E-34 T 31-10-2018 IPR035439 UPF0145 domain superfamily DFR85_15060 f813b5cd9e5460999625921f9a508314 114 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 8 110 24.163 T 31-10-2018 IPR002765 Uncharacterised protein family UPF0145 DFR85_13875 f76c93c301c39f56ed157e69a8cf8fd3 73 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 52 63 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR85_13875 f76c93c301c39f56ed157e69a8cf8fd3 73 SUPERFAMILY SSF54862 10 72 4.36E-19 T 31-10-2018 DFR85_13875 f76c93c301c39f56ed157e69a8cf8fd3 73 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 3 73 9.0E-30 T 31-10-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 DFR85_13875 f76c93c301c39f56ed157e69a8cf8fd3 73 Pfam PF14697 4Fe-4S dicluster domain 21 69 3.8E-10 T 31-10-2018 DFR85_13875 f76c93c301c39f56ed157e69a8cf8fd3 73 Gene3D G3DSA:3.30.70.20 5 73 9.5E-15 T 31-10-2018 DFR85_12105 574a6d40a79098e5adf83891aa291eae 243 Gene3D G3DSA:3.30.70.3120 6 243 1.0E-32 T 31-10-2018 DFR85_12105 574a6d40a79098e5adf83891aa291eae 243 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 9 47 4.6E-6 T 31-10-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal DFR85_12105 574a6d40a79098e5adf83891aa291eae 243 TIGRFAM TIGR01874 cas_cas5a: CRISPR-associated protein Cas5, subtype I-A/APERN 9 180 8.5E-39 T 31-10-2018 IPR010153 CRISPR-associated protein, Cas5a type DFR85_04195 6ed5e7ad909ad610b4d4638b9056099b 649 Gene3D G3DSA:1.50.10.10 323 621 2.1E-22 T 31-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 DFR85_04195 6ed5e7ad909ad610b4d4638b9056099b 649 SUPERFAMILY SSF48208 267 638 1.42E-33 T 31-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 DFR85_04195 6ed5e7ad909ad610b4d4638b9056099b 649 Pfam PF04685 Glycosyl-hydrolase family 116, catalytic region 305 638 7.6E-78 T 31-10-2018 IPR006775 Glycosyl-hydrolase family 116, catalytic region GO:0004553 KEGG: 00511+3.2.1.45|KEGG: 00600+3.2.1.45|Reactome: R-HSA-1660662 DFR85_04195 6ed5e7ad909ad610b4d4638b9056099b 649 Pfam PF12215 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term 8 271 8.7E-12 T 31-10-2018 IPR024462 Glycosyl-hydrolase family 116, N-terminal KEGG: 00511+3.2.1.45|KEGG: 00600+3.2.1.45|Reactome: R-HSA-1660662 DFR85_06435 0d3bec1c4d715582361ccfdf756e19fb 370 Gene3D G3DSA:3.30.300.10 195 309 8.9E-14 T 31-10-2018 DFR85_06435 0d3bec1c4d715582361ccfdf756e19fb 370 Pfam PF00958 GMP synthase C terminal domain 313 369 5.8E-18 T 31-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 DFR85_06435 0d3bec1c4d715582361ccfdf756e19fb 370 Pfam PF02540 NAD synthase 14 191 3.4E-10 T 31-10-2018 IPR022310 NAD/GMP synthase DFR85_06435 0d3bec1c4d715582361ccfdf756e19fb 370 Gene3D G3DSA:3.30.300.10 310 370 1.1E-19 T 31-10-2018 DFR85_06435 0d3bec1c4d715582361ccfdf756e19fb 370 SUPERFAMILY SSF54810 194 370 9.29E-29 T 31-10-2018 DFR85_06435 0d3bec1c4d715582361ccfdf756e19fb 370 Gene3D G3DSA:3.40.50.620 2 194 2.4E-60 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR85_06435 0d3bec1c4d715582361ccfdf756e19fb 370 SUPERFAMILY SSF52402 2 221 7.5E-41 T 31-10-2018 DFR85_04945 d17e7454fc69147646a367574566ab68 344 SUPERFAMILY SSF53756 18 336 2.56E-33 T 31-10-2018 DFR85_04945 d17e7454fc69147646a367574566ab68 344 Pfam PF13692 Glycosyl transferases group 1 179 302 8.4E-10 T 31-10-2018 DFR85_04945 d17e7454fc69147646a367574566ab68 344 Gene3D G3DSA:3.40.50.2000 159 313 5.1E-19 T 31-10-2018 DFR85_11955 9952c2f62e81816c0626122f7e9aea13 309 Gene3D G3DSA:3.30.2010.10 65 153 6.3E-21 T 31-10-2018 DFR85_11955 9952c2f62e81816c0626122f7e9aea13 309 Pfam PF01435 Peptidase family M48 75 302 2.8E-33 T 31-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 DFR85_11955 9952c2f62e81816c0626122f7e9aea13 309 Hamap MF_00188 Protease HtpX [htpX]. 6 305 24.846 T 31-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 DFR85_14780 19f38985e8fea7051f14b30ca191e593 245 Gene3D G3DSA:3.60.15.10 1 245 2.9E-65 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR85_14780 19f38985e8fea7051f14b30ca191e593 245 SUPERFAMILY SSF56281 5 219 1.35E-43 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR85_14780 19f38985e8fea7051f14b30ca191e593 245 SMART SM00849 12 182 1.6E-29 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR85_14780 19f38985e8fea7051f14b30ca191e593 245 Pfam PF00753 Metallo-beta-lactamase superfamily 22 182 1.6E-9 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR85_04110 5f1becaa3ef34947c9be3bb98d7a3a42 860 SUPERFAMILY SSF48208 332 799 5.44E-23 T 31-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 DFR85_04110 5f1becaa3ef34947c9be3bb98d7a3a42 860 Pfam PF04685 Glycosyl-hydrolase family 116, catalytic region 557 738 5.4E-28 T 31-10-2018 IPR006775 Glycosyl-hydrolase family 116, catalytic region GO:0004553 KEGG: 00511+3.2.1.45|KEGG: 00600+3.2.1.45|Reactome: R-HSA-1660662 DFR85_04110 5f1becaa3ef34947c9be3bb98d7a3a42 860 Pfam PF04685 Glycosyl-hydrolase family 116, catalytic region 352 516 1.8E-7 T 31-10-2018 IPR006775 Glycosyl-hydrolase family 116, catalytic region GO:0004553 KEGG: 00511+3.2.1.45|KEGG: 00600+3.2.1.45|Reactome: R-HSA-1660662 DFR85_04110 5f1becaa3ef34947c9be3bb98d7a3a42 860 Gene3D G3DSA:1.50.10.10 427 755 3.5E-9 T 31-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 DFR85_04110 5f1becaa3ef34947c9be3bb98d7a3a42 860 Pfam PF12215 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term 12 281 8.9E-26 T 31-10-2018 IPR024462 Glycosyl-hydrolase family 116, N-terminal KEGG: 00511+3.2.1.45|KEGG: 00600+3.2.1.45|Reactome: R-HSA-1660662 DFR85_04530 4a9aaf56a5bb5ed79a25ecde10726b87 514 SUPERFAMILY SSF56112 188 436 1.89E-67 T 31-10-2018 IPR011009 Protein kinase-like domain superfamily DFR85_04530 4a9aaf56a5bb5ed79a25ecde10726b87 514 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 297 309 - T 31-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 DFR85_04530 4a9aaf56a5bb5ed79a25ecde10726b87 514 Gene3D G3DSA:1.10.510.10 175 457 1.8E-64 T 31-10-2018 DFR85_04530 4a9aaf56a5bb5ed79a25ecde10726b87 514 Pfam PF00069 Protein kinase domain 192 427 1.6E-46 T 31-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DFR85_04530 4a9aaf56a5bb5ed79a25ecde10726b87 514 Pfam PF13240 zinc-ribbon domain 69 91 6.0E-7 T 31-10-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 DFR85_04530 4a9aaf56a5bb5ed79a25ecde10726b87 514 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 198 221 - T 31-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 DFR85_04530 4a9aaf56a5bb5ed79a25ecde10726b87 514 SMART SM00220 192 435 5.3E-51 T 31-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 DFR85_10640 b636f68b43cf1da5c84e01a39c77424e 218 Gene3D G3DSA:3.20.20.140 1 173 2.0E-37 T 31-10-2018 DFR85_10640 b636f68b43cf1da5c84e01a39c77424e 218 SUPERFAMILY SSF89550 2 181 1.47E-36 T 31-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 DFR85_10640 b636f68b43cf1da5c84e01a39c77424e 218 SMART SM00481 3 60 2.3E-10 T 31-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal DFR85_10640 b636f68b43cf1da5c84e01a39c77424e 218 Pfam PF13263 PHP-associated 127 175 7.9E-11 T 31-10-2018 DFR85_00260 4654a1ddf54ff71b89a11e684ffa5073 213 TIGRFAM TIGR02694 arsenite_ox_S: arsenite oxidase, small subunit 80 205 7.6E-31 T 31-10-2018 IPR014067 Arsenite oxidase, small subunit MetaCyc: PWY-7429 DFR85_00260 4654a1ddf54ff71b89a11e684ffa5073 213 SUPERFAMILY SSF50022 82 203 2.1E-24 T 31-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 DFR85_00260 4654a1ddf54ff71b89a11e684ffa5073 213 Pfam PF00355 Rieske [2Fe-2S] domain 84 164 3.8E-10 T 31-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DFR85_00260 4654a1ddf54ff71b89a11e684ffa5073 213 Gene3D G3DSA:2.102.10.10 77 206 5.7E-31 T 31-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 DFR85_00825 883b9b284994a6208852b56c9438aa0a 171 SUPERFAMILY SSF49764 79 171 8.77E-24 T 31-10-2018 IPR008978 HSP20-like chaperone DFR85_00825 883b9b284994a6208852b56c9438aa0a 171 Pfam PF00011 Hsp20/alpha crystallin family 87 170 3.9E-12 T 31-10-2018 IPR002068 Alpha crystallin/Hsp20 domain DFR85_00825 883b9b284994a6208852b56c9438aa0a 171 Gene3D G3DSA:2.60.40.790 76 161 9.6E-24 T 31-10-2018 IPR008978 HSP20-like chaperone DFR85_07185 7d2a24140d2ac1c57ef2a99be02bad97 232 Gene3D G3DSA:3.30.70.240 162 231 4.5E-24 T 31-10-2018 DFR85_07185 7d2a24140d2ac1c57ef2a99be02bad97 232 SUPERFAMILY SSF89895 3 84 3.92E-22 T 31-10-2018 IPR036786 Ribosome maturation protein SBDS, N-terminal domain superfamily DFR85_07185 7d2a24140d2ac1c57ef2a99be02bad97 232 SUPERFAMILY SSF54980 155 227 3.2E-18 T 31-10-2018 IPR035647 EF-G domain III/V-like DFR85_07185 7d2a24140d2ac1c57ef2a99be02bad97 232 Pfam PF01172 Shwachman-Bodian-Diamond syndrome (SBDS) protein 7 92 8.7E-23 T 31-10-2018 IPR019783 Ribosome maturation protein SBDS, N-terminal DFR85_07185 7d2a24140d2ac1c57ef2a99be02bad97 232 TIGRFAM TIGR00291 RNA_SBDS: rRNA metabolism protein, SBDS family 5 230 3.2E-67 T 31-10-2018 IPR002140 Ribosome maturation protein Sdo1/SBDS GO:0042256 DFR85_07185 7d2a24140d2ac1c57ef2a99be02bad97 232 Gene3D G3DSA:1.10.10.900 86 160 7.1E-28 T 31-10-2018 IPR037188 Ribosome maturation protein Sdo1/SBDS, central domain superfamily DFR85_07185 7d2a24140d2ac1c57ef2a99be02bad97 232 Pfam PF09377 SBDS protein C-terminal domain 99 214 1.5E-20 T 31-10-2018 IPR018978 Ribosome maturation protein SBDS, C-terminal GO:0042254 DFR85_07185 7d2a24140d2ac1c57ef2a99be02bad97 232 Gene3D G3DSA:3.30.1250.10 6 85 2.0E-25 T 31-10-2018 IPR036786 Ribosome maturation protein SBDS, N-terminal domain superfamily DFR85_07185 7d2a24140d2ac1c57ef2a99be02bad97 232 SUPERFAMILY SSF109728 81 153 1.83E-22 T 31-10-2018 IPR037188 Ribosome maturation protein Sdo1/SBDS, central domain superfamily DFR85_03520 7df356615cd61720d76c4680070d13ec 258 SUPERFAMILY SSF53474 11 257 2.48E-36 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold DFR85_03520 7df356615cd61720d76c4680070d13ec 258 Gene3D G3DSA:3.40.50.1820 6 257 2.3E-35 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold DFR85_03520 7df356615cd61720d76c4680070d13ec 258 Pfam PF12697 Alpha/beta hydrolase family 28 250 1.3E-6 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 DFR85_15350 a32d6456e8b8f6e3e7bdbbe1d589cd51 522 Pfam PF00501 AMP-binding enzyme 22 418 3.3E-88 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 DFR85_15350 a32d6456e8b8f6e3e7bdbbe1d589cd51 522 ProSitePatterns PS00455 Putative AMP-binding domain signature. 166 177 - T 31-10-2018 IPR020845 AMP-binding, conserved site DFR85_15350 a32d6456e8b8f6e3e7bdbbe1d589cd51 522 Gene3D G3DSA:3.40.50.12780 1 413 2.9E-106 T 31-10-2018 DFR85_15350 a32d6456e8b8f6e3e7bdbbe1d589cd51 522 Pfam PF13193 AMP-binding enzyme C-terminal domain 428 504 4.4E-18 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain DFR85_15350 a32d6456e8b8f6e3e7bdbbe1d589cd51 522 Gene3D G3DSA:3.30.300.310 414 519 5.4E-31 T 31-10-2018 DFR85_15350 a32d6456e8b8f6e3e7bdbbe1d589cd51 522 SUPERFAMILY SSF56801 5 515 1.09E-130 T 31-10-2018 DFR85_14645 d80ec225e8b44a3cded459fbc6c8c037 161 Gene3D G3DSA:3.40.630.30 7 158 7.7E-39 T 31-10-2018 DFR85_14645 d80ec225e8b44a3cded459fbc6c8c037 161 Pfam PF00583 Acetyltransferase (GNAT) family 45 133 5.1E-13 T 31-10-2018 IPR000182 GNAT domain DFR85_14645 d80ec225e8b44a3cded459fbc6c8c037 161 SUPERFAMILY SSF55729 7 140 5.65E-26 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase DFR85_02375 fba61b0a91fe30d8386f3779395d5ab1 425 Pfam PF13520 Amino acid permease 7 387 1.1E-34 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_02375 fba61b0a91fe30d8386f3779395d5ab1 425 PIRSF PIRSF006060 1 424 2.2E-63 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_02375 fba61b0a91fe30d8386f3779395d5ab1 425 Gene3D G3DSA:1.20.1740.10 2 424 4.3E-78 T 31-10-2018 DFR85_03135 0e970ab963ab6be01049d27ee878446e 500 Gene3D G3DSA:1.20.1740.10 14 490 2.3E-18 T 31-10-2018 DFR85_03135 0e970ab963ab6be01049d27ee878446e 500 Pfam PF13520 Amino acid permease 23 444 4.0E-23 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_03135 0e970ab963ab6be01049d27ee878446e 500 PIRSF PIRSF006060 4 497 1.2E-35 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_05440 20ec612eacf999a9e3857a381e39bd7b 240 SUPERFAMILY SSF55681 1 238 1.63E-45 T 31-10-2018 DFR85_05440 20ec612eacf999a9e3857a381e39bd7b 240 Gene3D G3DSA:3.30.930.10 1 240 1.9E-44 T 31-10-2018 DFR85_13485 0f4eb4ebd4407f4573ddd88107d09b29 231 Gene3D G3DSA:3.30.70.1900 96 231 1.7E-11 T 31-10-2018 DFR85_13485 0f4eb4ebd4407f4573ddd88107d09b29 231 Pfam PF10040 CRISPR-associated endoribonuclease Cas6 154 227 2.1E-5 T 31-10-2018 IPR019267 CRISPR-associated protein Cas6, C-terminal DFR85_03425 05fd905d77a153664d06c73ce23993d7 239 Pfam PF13247 4Fe-4S dicluster domain 78 188 6.4E-12 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR85_03425 05fd905d77a153664d06c73ce23993d7 239 SUPERFAMILY SSF54862 27 222 1.67E-54 T 31-10-2018 DFR85_03425 05fd905d77a153664d06c73ce23993d7 239 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 116 127 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR85_03425 05fd905d77a153664d06c73ce23993d7 239 Gene3D G3DSA:3.30.70.20 48 237 1.0E-51 T 31-10-2018 DFR85_12150 78b4a39040fc820d8feeb75c8ae265cb 176 Gene3D G3DSA:3.90.320.10 2 174 1.6E-13 T 31-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal DFR85_12150 78b4a39040fc820d8feeb75c8ae265cb 176 Pfam PF01930 Domain of unknown function DUF83 5 171 2.5E-18 T 31-10-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 DFR85_12150 78b4a39040fc820d8feeb75c8ae265cb 176 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 2 172 1.5E-30 T 31-10-2018 IPR013343 CRISPR-associated protein Cas4 DFR85_14220 32b35e0e78a4b5d9a232bf1b206d9ff5 443 Pfam PF14720 NiFe/NiFeSe hydrogenase small subunit C-terminal 319 396 8.6E-22 T 31-10-2018 IPR027394 Cytochrome-c3 hydrogenase, C-terminal DFR85_14220 32b35e0e78a4b5d9a232bf1b206d9ff5 443 Gene3D G3DSA:4.10.480.10 319 398 2.3E-23 T 31-10-2018 IPR037148 [NiFe]-hydrogenase, small subunit, C-terminal domain superfamily DFR85_14220 32b35e0e78a4b5d9a232bf1b206d9ff5 443 PIRSF PIRSF000310 1 442 5.2E-61 T 31-10-2018 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 DFR85_14220 32b35e0e78a4b5d9a232bf1b206d9ff5 443 SUPERFAMILY SSF56770 42 397 4.06E-39 T 31-10-2018 DFR85_14220 32b35e0e78a4b5d9a232bf1b206d9ff5 443 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 52 293 2.3E-11 T 31-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_09065 67ff1fe5ac960151e6519164d53206d3 229 Pfam PF00571 CBS domain 6 52 9.6E-5 T 31-10-2018 IPR000644 CBS domain DFR85_09065 67ff1fe5ac960151e6519164d53206d3 229 Pfam PF00571 CBS domain 118 163 1.8E-7 T 31-10-2018 IPR000644 CBS domain DFR85_09065 67ff1fe5ac960151e6519164d53206d3 229 SUPERFAMILY SSF54631 113 226 1.62E-17 T 31-10-2018 DFR85_09065 67ff1fe5ac960151e6519164d53206d3 229 Gene3D G3DSA:3.10.580.10 115 225 1.8E-16 T 31-10-2018 DFR85_09065 67ff1fe5ac960151e6519164d53206d3 229 Gene3D G3DSA:3.10.580.10 2 108 6.8E-9 T 31-10-2018 DFR85_09065 67ff1fe5ac960151e6519164d53206d3 229 SUPERFAMILY SSF54631 5 104 2.81E-9 T 31-10-2018 DFR85_09065 67ff1fe5ac960151e6519164d53206d3 229 SMART SM00116 6 53 4.9 T 31-10-2018 IPR000644 CBS domain DFR85_09065 67ff1fe5ac960151e6519164d53206d3 229 SMART SM00116 120 166 4.5E-4 T 31-10-2018 IPR000644 CBS domain DFR85_09065 67ff1fe5ac960151e6519164d53206d3 229 SMART SM00116 182 225 14.0 T 31-10-2018 IPR000644 CBS domain DFR85_00895 b53af0d8e5402c2b6ea175e9786422d5 253 Pfam PF02475 Met-10+ like-protein 11 206 5.0E-44 T 31-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 DFR85_00895 b53af0d8e5402c2b6ea175e9786422d5 253 Gene3D G3DSA:3.40.50.150 10 253 1.8E-46 T 31-10-2018 DFR85_00895 b53af0d8e5402c2b6ea175e9786422d5 253 SUPERFAMILY SSF53335 6 252 5.44E-46 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR85_08465 79710a2a019ef1e3076ee16e88a7f7be 494 Gene3D G3DSA:3.40.50.300 2 316 2.8E-24 T 31-10-2018 DFR85_08465 79710a2a019ef1e3076ee16e88a7f7be 494 SUPERFAMILY SSF52540 2 297 4.09E-25 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_08465 79710a2a019ef1e3076ee16e88a7f7be 494 Pfam PF13175 AAA ATPase domain 96 285 1.1E-19 T 31-10-2018 DFR85_09300 8240ac2af75eab78b6fe6b9f00c8c534 321 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 159 315 3.6E-17 T 31-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 DFR85_09300 8240ac2af75eab78b6fe6b9f00c8c534 321 Gene3D G3DSA:3.40.50.300 151 321 1.0E-47 T 31-10-2018 DFR85_09300 8240ac2af75eab78b6fe6b9f00c8c534 321 Gene3D G3DSA:1.20.120.1190 2 150 6.0E-12 T 31-10-2018 DFR85_09300 8240ac2af75eab78b6fe6b9f00c8c534 321 SUPERFAMILY SSF52540 150 320 5.88E-39 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_09300 8240ac2af75eab78b6fe6b9f00c8c534 321 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 181 199 3.1E-13 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 DFR85_09300 8240ac2af75eab78b6fe6b9f00c8c534 321 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 160 180 3.1E-13 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 DFR85_09300 8240ac2af75eab78b6fe6b9f00c8c534 321 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 208 223 3.1E-13 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 DFR85_09300 8240ac2af75eab78b6fe6b9f00c8c534 321 Pfam PF01926 50S ribosome-binding GTPase 160 277 2.0E-21 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 DFR85_07710 1689d3db67dda5f9d748667852635fd0 81 Pfam PF01200 Ribosomal protein S28e 17 77 3.3E-30 T 31-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07710 1689d3db67dda5f9d748667852635fd0 81 SUPERFAMILY SSF50249 15 79 1.11E-24 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR85_07710 1689d3db67dda5f9d748667852635fd0 81 Hamap MF_00292 30S ribosomal protein S28e [rps28e]. 1 78 25.253 T 31-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07710 1689d3db67dda5f9d748667852635fd0 81 Gene3D G3DSA:2.40.50.140 11 81 1.4E-31 T 31-10-2018 DFR85_07710 1689d3db67dda5f9d748667852635fd0 81 ProSitePatterns PS00961 Ribosomal protein S28e signature. 69 77 - T 31-10-2018 IPR028626 Ribosomal protein S28e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07710 1689d3db67dda5f9d748667852635fd0 81 ProDom PD005541 RIBOSOMAL RIBONUCLEOPROTEIN 40S S28 S28E 30S ACETYLATION S33 S33 CG15527 19 59 3.0E-15 T 31-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_12635 8ecf7c090ce9814d044973a3b6f5521f 373 Pfam PF13378 Enolase C-terminal domain-like 148 344 5.4E-40 T 31-10-2018 IPR029065 Enolase C-terminal domain-like DFR85_12635 8ecf7c090ce9814d044973a3b6f5521f 373 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 183 214 - T 31-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 DFR85_12635 8ecf7c090ce9814d044973a3b6f5521f 373 SMART SM00922 140 234 1.0E-12 T 31-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal DFR85_12635 8ecf7c090ce9814d044973a3b6f5521f 373 SUPERFAMILY SSF51604 110 354 2.88E-48 T 31-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily DFR85_12635 8ecf7c090ce9814d044973a3b6f5521f 373 SUPERFAMILY SSF54826 2 124 6.73E-17 T 31-10-2018 DFR85_12635 8ecf7c090ce9814d044973a3b6f5521f 373 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 25 121 3.7E-7 T 31-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain DFR85_12635 8ecf7c090ce9814d044973a3b6f5521f 373 Gene3D G3DSA:3.30.390.10 1 119 8.6E-15 T 31-10-2018 IPR029017 Enolase-like, N-terminal DFR85_12635 8ecf7c090ce9814d044973a3b6f5521f 373 Gene3D G3DSA:3.20.20.120 120 361 2.8E-50 T 31-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily DFR85_03335 a42ef7fc38ad8bd5b6af210a7e171c8b 89 SUPERFAMILY SSF54862 4 82 1.32E-17 T 31-10-2018 DFR85_03335 a42ef7fc38ad8bd5b6af210a7e171c8b 89 Pfam PF13237 4Fe-4S dicluster domain 20 71 3.6E-7 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR85_03335 a42ef7fc38ad8bd5b6af210a7e171c8b 89 PIRSF PIRSF036548 2 89 6.3E-19 T 31-10-2018 IPR012206 Ferredoxin-like, FixX GO:0005506 DFR85_03335 a42ef7fc38ad8bd5b6af210a7e171c8b 89 Gene3D G3DSA:3.30.70.20 7 85 1.4E-12 T 31-10-2018 DFR85_07590 6d17b907138f0bdeefa7649d59e9919a 174 TIGRFAM TIGR01527 arch_NMN_Atrans: nicotinamide-nucleotide adenylyltransferase 3 169 1.9E-75 T 31-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 DFR85_07590 6d17b907138f0bdeefa7649d59e9919a 174 SUPERFAMILY SSF52374 3 164 1.29E-34 T 31-10-2018 DFR85_07590 6d17b907138f0bdeefa7649d59e9919a 174 Hamap MF_00243 Nicotinamide-nucleotide adenylyltransferase. 1 174 83.761 T 31-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 DFR85_07590 6d17b907138f0bdeefa7649d59e9919a 174 Gene3D G3DSA:3.40.50.620 2 173 7.8E-54 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR85_07590 6d17b907138f0bdeefa7649d59e9919a 174 Pfam PF01467 Cytidylyltransferase-like 5 135 1.5E-15 T 31-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 DFR85_07590 6d17b907138f0bdeefa7649d59e9919a 174 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 62 2.0E-16 T 31-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 DFR85_07250 be765c2ffe9db37b518d4f4864a46b69 112 Gene3D G3DSA:1.10.150.820 48 87 1.4E-14 T 31-10-2018 DFR85_07250 be765c2ffe9db37b518d4f4864a46b69 112 PIRSF PIRSF005053 1 111 6.5E-26 T 31-10-2018 IPR010924 DNA-directed RNA polymerase subunit F (Rpo4) DFR85_07250 be765c2ffe9db37b518d4f4864a46b69 112 Pfam PF03874 RNA polymerase Rpb4 31 109 2.0E-6 T 31-10-2018 IPR005574 RNA polymerase subunit RPB4/RPC9 GO:0006352|GO:0030880 DFR85_07250 be765c2ffe9db37b518d4f4864a46b69 112 SUPERFAMILY SSF47819 1 106 1.03E-22 T 31-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 DFR85_14950 dd5a9ed46a88927751ac0b39d2c09bd0 85 Gene3D G3DSA:2.10.260.10 5 43 4.5E-8 T 31-10-2018 DFR85_14950 dd5a9ed46a88927751ac0b39d2c09bd0 85 SMART SM00966 5 50 9.8E-9 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR85_14950 dd5a9ed46a88927751ac0b39d2c09bd0 85 SUPERFAMILY SSF89447 6 56 6.8E-12 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily DFR85_14950 dd5a9ed46a88927751ac0b39d2c09bd0 85 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 7 46 1.2E-8 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR85_14950 dd5a9ed46a88927751ac0b39d2c09bd0 85 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 4 46 1.8E-14 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR85_01125 1e2582ecc1c72882f86978fbebb01afe 414 Gene3D G3DSA:2.160.10.10 283 373 4.8E-12 T 31-10-2018 DFR85_01125 1e2582ecc1c72882f86978fbebb01afe 414 SUPERFAMILY SSF53448 8 365 1.51E-60 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_01125 1e2582ecc1c72882f86978fbebb01afe 414 Gene3D G3DSA:2.160.10.10 374 414 2.2E-5 T 31-10-2018 DFR85_01125 1e2582ecc1c72882f86978fbebb01afe 414 SUPERFAMILY SSF51161 359 411 1.44E-7 T 31-10-2018 IPR011004 Trimeric LpxA-like superfamily DFR85_01125 1e2582ecc1c72882f86978fbebb01afe 414 Gene3D G3DSA:3.90.550.10 2 277 1.4E-62 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_01125 1e2582ecc1c72882f86978fbebb01afe 414 Pfam PF00483 Nucleotidyl transferase 10 259 3.1E-42 T 31-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 DFR85_08485 696c72cb565f1a573861103f32928966 141 Gene3D G3DSA:3.90.79.10 1 133 1.1E-37 T 31-10-2018 DFR85_08485 696c72cb565f1a573861103f32928966 141 SUPERFAMILY SSF55811 2 128 1.16E-35 T 31-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 DFR85_08485 696c72cb565f1a573861103f32928966 141 PRINTS PR00502 NUDIX hydrolase family signature 46 61 9.5E-8 T 31-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 DFR85_08485 696c72cb565f1a573861103f32928966 141 PRINTS PR00502 NUDIX hydrolase family signature 32 46 9.5E-8 T 31-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 DFR85_08485 696c72cb565f1a573861103f32928966 141 ProSitePatterns PS00893 Nudix box signature. 37 58 - T 31-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 DFR85_08485 696c72cb565f1a573861103f32928966 141 Pfam PF00293 NUDIX domain 6 119 2.1E-19 T 31-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 DFR85_06545 35b34d18447816136f75fcd81d510a29 257 Gene3D G3DSA:3.40.1180.10 11 257 1.5E-82 T 31-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 DFR85_06545 35b34d18447816136f75fcd81d510a29 257 SUPERFAMILY SSF64005 21 251 1.31E-70 T 31-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 DFR85_06545 35b34d18447816136f75fcd81d510a29 257 Pfam PF01255 Putative undecaprenyl diphosphate synthase 33 256 2.6E-68 T 31-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 DFR85_06545 35b34d18447816136f75fcd81d510a29 257 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 26 257 35.275 T 31-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 DFR85_06545 35b34d18447816136f75fcd81d510a29 257 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 202 219 - T 31-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 DFR85_06545 35b34d18447816136f75fcd81d510a29 257 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 26 256 2.2E-69 T 31-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 DFR85_05115 96e8700683d70960ea2748e08b2a878f 188 SUPERFAMILY SSF103473 13 159 7.85E-6 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_05115 96e8700683d70960ea2748e08b2a878f 188 Gene3D G3DSA:1.20.1250.20 4 179 1.8E-6 T 31-10-2018 DFR85_11275 1078d484c79e062d6887a391c5b0f04c 229 SUPERFAMILY SSF53448 1 220 2.82E-59 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_11275 1078d484c79e062d6887a391c5b0f04c 229 Pfam PF00483 Nucleotidyl transferase 2 220 1.1E-32 T 31-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 DFR85_11275 1078d484c79e062d6887a391c5b0f04c 229 Gene3D G3DSA:3.90.550.10 1 223 2.7E-62 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_14955 3c9359c530ec636f95cc0cb809beb561 121 SMART SM00670 1 119 7.4E-7 T 31-10-2018 IPR002716 PIN domain DFR85_14955 3c9359c530ec636f95cc0cb809beb561 121 Gene3D G3DSA:3.40.50.1010 1 121 5.3E-15 T 31-10-2018 DFR85_14955 3c9359c530ec636f95cc0cb809beb561 121 Pfam PF01850 PIN domain 2 120 8.2E-18 T 31-10-2018 IPR002716 PIN domain DFR85_14955 3c9359c530ec636f95cc0cb809beb561 121 SUPERFAMILY SSF88723 2 120 5.05E-18 T 31-10-2018 IPR029060 PIN-like domain superfamily DFR85_11420 1d3a37f1406de9a05b18f83249f7522f 80 Gene3D G3DSA:3.30.110.40 3 80 8.5E-30 T 31-10-2018 IPR036868 TusA-like domain superfamily DFR85_11420 1d3a37f1406de9a05b18f83249f7522f 80 Pfam PF01206 Sulfurtransferase TusA 9 78 9.0E-23 T 31-10-2018 IPR001455 TusA-like domain DFR85_11420 1d3a37f1406de9a05b18f83249f7522f 80 SUPERFAMILY SSF64307 4 78 5.23E-24 T 31-10-2018 IPR036868 TusA-like domain superfamily DFR85_11420 1d3a37f1406de9a05b18f83249f7522f 80 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 11 35 - T 31-10-2018 IPR001455 TusA-like domain DFR85_13830 716a34bc0f33d5e54e3772ce07980018 357 PIRSF PIRSF000429 4 341 3.2E-12 T 31-10-2018 IPR002155 Thiolase GO:0016747 DFR85_13830 716a34bc0f33d5e54e3772ce07980018 357 SUPERFAMILY SSF53901 229 346 2.35E-16 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR85_13830 716a34bc0f33d5e54e3772ce07980018 357 Gene3D G3DSA:3.40.47.10 3 357 3.1E-48 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR85_13830 716a34bc0f33d5e54e3772ce07980018 357 SUPERFAMILY SSF53901 6 226 7.2E-12 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR85_01260 ff53763131ee8a8827e829f2427912f6 330 SMART SM00933 49 303 2.6E-30 T 31-10-2018 IPR018977 NurA domain DFR85_01260 ff53763131ee8a8827e829f2427912f6 330 Pfam PF09376 NurA domain 51 303 2.1E-24 T 31-10-2018 IPR018977 NurA domain DFR85_06895 677c9cfa51f0554ee672416e5d1d6b6a 300 Gene3D G3DSA:3.30.460.10 98 195 2.7E-5 T 31-10-2018 DFR85_06895 677c9cfa51f0554ee672416e5d1d6b6a 300 SUPERFAMILY SSF81301 101 162 3.31E-6 T 31-10-2018 DFR85_06895 677c9cfa51f0554ee672416e5d1d6b6a 300 Pfam PF01909 Nucleotidyltransferase domain 117 185 6.1E-5 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 DFR85_15015 749876acb05f449f84ac9186f3ae3036 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 7.3E-37 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_15015 749876acb05f449f84ac9186f3ae3036 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 7.3E-37 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_15015 749876acb05f449f84ac9186f3ae3036 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 7.3E-37 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_15015 749876acb05f449f84ac9186f3ae3036 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 7.3E-37 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_15015 749876acb05f449f84ac9186f3ae3036 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 7.3E-37 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_15015 749876acb05f449f84ac9186f3ae3036 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 181 7.3E-37 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_15015 749876acb05f449f84ac9186f3ae3036 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 131 159 - T 31-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DFR85_15015 749876acb05f449f84ac9186f3ae3036 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 242 2.3E-54 T 31-10-2018 DFR85_15015 749876acb05f449f84ac9186f3ae3036 253 SUPERFAMILY SSF51735 6 242 4.0E-70 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_15015 749876acb05f449f84ac9186f3ae3036 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 124 132 8.3E-13 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_15015 749876acb05f449f84ac9186f3ae3036 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 163 8.3E-13 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_15015 749876acb05f449f84ac9186f3ae3036 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 71 82 8.3E-13 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_15015 749876acb05f449f84ac9186f3ae3036 253 Gene3D G3DSA:3.40.50.720 4 250 4.0E-73 T 31-10-2018 DFR85_04930 f131cc19c644a544cea1537861d6cf13 300 SUPERFAMILY SSF53448 54 290 1.58E-9 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_01105 3ea7293c871faf46daeda83e4ca45a9e 68 Gene3D G3DSA:3.10.20.30 1 68 1.6E-17 T 31-10-2018 IPR012675 Beta-grasp domain superfamily DFR85_01105 3ea7293c871faf46daeda83e4ca45a9e 68 Pfam PF02597 ThiS family 9 68 3.4E-6 T 31-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 DFR85_01105 3ea7293c871faf46daeda83e4ca45a9e 68 SUPERFAMILY SSF54285 6 68 3.78E-10 T 31-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp DFR85_07160 e07a4accfffbc0b03d78a8be30e8af26 144 Gene3D G3DSA:3.40.50.10480 1 142 1.7E-14 T 31-10-2018 DFR85_07160 e07a4accfffbc0b03d78a8be30e8af26 144 SUPERFAMILY SSF52954 2 86 4.41E-15 T 31-10-2018 DFR85_14740 f2103b86e58af0c3ef1edb3b7387978f 290 SMART SM01130 1 282 1.3E-51 T 31-10-2018 IPR002220 DapA-like GO:0016829 DFR85_14740 f2103b86e58af0c3ef1edb3b7387978f 290 Gene3D G3DSA:3.20.20.70 1 290 3.0E-88 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_14740 f2103b86e58af0c3ef1edb3b7387978f 290 PRINTS PR00146 Dihydrodipicolinate synthase signature 33 54 1.4E-9 T 31-10-2018 IPR002220 DapA-like GO:0016829 DFR85_14740 f2103b86e58af0c3ef1edb3b7387978f 290 PRINTS PR00146 Dihydrodipicolinate synthase signature 66 84 1.4E-9 T 31-10-2018 IPR002220 DapA-like GO:0016829 DFR85_14740 f2103b86e58af0c3ef1edb3b7387978f 290 PRINTS PR00146 Dihydrodipicolinate synthase signature 124 141 1.4E-9 T 31-10-2018 IPR002220 DapA-like GO:0016829 DFR85_14740 f2103b86e58af0c3ef1edb3b7387978f 290 SUPERFAMILY SSF51569 3 281 3.35E-61 T 31-10-2018 DFR85_14740 f2103b86e58af0c3ef1edb3b7387978f 290 PIRSF PIRSF001365 1 289 2.9E-56 T 31-10-2018 IPR002220 DapA-like GO:0016829 DFR85_14740 f2103b86e58af0c3ef1edb3b7387978f 290 Pfam PF00701 Dihydrodipicolinate synthetase family 2 275 3.6E-43 T 31-10-2018 IPR002220 DapA-like GO:0016829 DFR85_06350 cff044f2e13c25bbc5fa33ec62a3f363 289 SUPERFAMILY SSF53613 3 273 1.45E-68 T 31-10-2018 IPR029056 Ribokinase-like DFR85_06350 cff044f2e13c25bbc5fa33ec62a3f363 289 Pfam PF00294 pfkB family carbohydrate kinase 2 274 5.9E-55 T 31-10-2018 IPR011611 Carbohydrate kinase PfkB DFR85_06350 cff044f2e13c25bbc5fa33ec62a3f363 289 Gene3D G3DSA:3.40.1190.20 1 288 1.6E-78 T 31-10-2018 IPR029056 Ribokinase-like DFR85_06350 cff044f2e13c25bbc5fa33ec62a3f363 289 PRINTS PR00990 Ribokinase signature 31 50 5.6E-27 T 31-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 DFR85_06350 cff044f2e13c25bbc5fa33ec62a3f363 289 PRINTS PR00990 Ribokinase signature 201 212 5.6E-27 T 31-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 DFR85_06350 cff044f2e13c25bbc5fa33ec62a3f363 289 PRINTS PR00990 Ribokinase signature 162 177 5.6E-27 T 31-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 DFR85_06350 cff044f2e13c25bbc5fa33ec62a3f363 289 PRINTS PR00990 Ribokinase signature 4 25 5.6E-27 T 31-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 DFR85_06350 cff044f2e13c25bbc5fa33ec62a3f363 289 Hamap MF_01987 Ribokinase [rbsK]. 1 283 20.273 T 31-10-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 DFR85_05800 1130b20a69713f5a55a93277c15f9d53 160 SUPERFAMILY SSF52016 3 158 1.65E-47 T 31-10-2018 DFR85_05800 1130b20a69713f5a55a93277c15f9d53 160 TIGRFAM TIGR02087 LEUD_arch: 3-isopropylmalate dehydratase, small subunit 5 157 1.4E-69 T 31-10-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0016836 KEGG: 00290+4.2.1.33 DFR85_05800 1130b20a69713f5a55a93277c15f9d53 160 Gene3D G3DSA:3.20.19.10 1 160 6.4E-56 T 31-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 DFR85_05800 1130b20a69713f5a55a93277c15f9d53 160 Hamap MF_01032 Methanogen homoaconitase small subunit [hacB]. 3 160 33.146 T 31-10-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0016836 KEGG: 00290+4.2.1.33 DFR85_05800 1130b20a69713f5a55a93277c15f9d53 160 Pfam PF00694 Aconitase C-terminal domain 45 101 2.1E-21 T 31-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 DFR85_09525 b54c3b4470d8462882ae5bf695d34ae4 164 TIGRFAM TIGR01685 MDP-1: magnesium-dependent phosphatase-1 3 160 2.5E-49 T 31-10-2018 IPR010036 Magnesium-dependent phosphatase-1, eukaryotic/archaeal-type GO:0016791 DFR85_09525 b54c3b4470d8462882ae5bf695d34ae4 164 SUPERFAMILY SSF56784 1 128 1.9E-19 T 31-10-2018 IPR036412 HAD-like superfamily DFR85_09525 b54c3b4470d8462882ae5bf695d34ae4 164 TIGRFAM TIGR01681 HAD-SF-IIIC: HAD phosphatase, family IIIC 4 138 1.0E-26 T 31-10-2018 IPR010033 HAD-superfamily phosphatase, subfamily IIIC DFR85_09525 b54c3b4470d8462882ae5bf695d34ae4 164 Pfam PF12689 Acid Phosphatase 4 84 3.3E-11 T 31-10-2018 IPR010036 Magnesium-dependent phosphatase-1, eukaryotic/archaeal-type GO:0016791 DFR85_09525 b54c3b4470d8462882ae5bf695d34ae4 164 Gene3D G3DSA:3.40.50.1000 2 163 4.2E-23 T 31-10-2018 IPR023214 HAD superfamily DFR85_02930 a2cfcf389d20798d674443f7f680f819 116 SUPERFAMILY SSF88723 1 116 1.65E-16 T 31-10-2018 IPR029060 PIN-like domain superfamily DFR85_02930 a2cfcf389d20798d674443f7f680f819 116 Pfam PF01850 PIN domain 3 115 2.1E-14 T 31-10-2018 IPR002716 PIN domain DFR85_02930 a2cfcf389d20798d674443f7f680f819 116 Gene3D G3DSA:3.40.50.1010 3 116 1.0E-11 T 31-10-2018 DFR85_15470 a41ce3e974f67cff9d93fa815849f516 429 Pfam PF07690 Major Facilitator Superfamily 52 372 9.1E-28 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_15470 a41ce3e974f67cff9d93fa815849f516 429 SUPERFAMILY SSF103473 14 425 5.1E-56 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_15470 a41ce3e974f67cff9d93fa815849f516 429 Gene3D G3DSA:1.20.1250.20 12 427 1.5E-53 T 31-10-2018 DFR85_15645 6c62bb6d5822139cf24a5a8c36d05e0d 621 SUPERFAMILY SSF56801 4 613 4.19E-133 T 31-10-2018 DFR85_15645 6c62bb6d5822139cf24a5a8c36d05e0d 621 Gene3D G3DSA:3.30.300.30 496 620 5.5E-17 T 31-10-2018 DFR85_15645 6c62bb6d5822139cf24a5a8c36d05e0d 621 ProSitePatterns PS00455 Putative AMP-binding domain signature. 239 250 - T 31-10-2018 IPR020845 AMP-binding, conserved site DFR85_15645 6c62bb6d5822139cf24a5a8c36d05e0d 621 Gene3D G3DSA:3.40.50.12780 39 494 1.1E-90 T 31-10-2018 DFR85_15645 6c62bb6d5822139cf24a5a8c36d05e0d 621 Pfam PF13193 AMP-binding enzyme C-terminal domain 509 584 1.4E-10 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain DFR85_15645 6c62bb6d5822139cf24a5a8c36d05e0d 621 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 13 64 1.2E-14 T 31-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 DFR85_15645 6c62bb6d5822139cf24a5a8c36d05e0d 621 Pfam PF00501 AMP-binding enzyme 66 498 1.8E-74 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 DFR85_12935 40d6732ec6d7e0cb18c2ec9c69075de9 132 SUPERFAMILY SSF55729 7 116 3.94E-9 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase DFR85_12935 40d6732ec6d7e0cb18c2ec9c69075de9 132 Gene3D G3DSA:3.40.630.30 1 119 1.1E-9 T 31-10-2018 DFR85_12935 40d6732ec6d7e0cb18c2ec9c69075de9 132 Pfam PF13673 Acetyltransferase (GNAT) domain 17 113 1.3E-7 T 31-10-2018 IPR000182 GNAT domain DFR85_10805 b5bb84cedd04eeb5ef89819e24bf1731 187 PRINTS PR00686 Transcription initiation factor TFIID signature 3 18 1.1E-44 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 DFR85_10805 b5bb84cedd04eeb5ef89819e24bf1731 187 PRINTS PR00686 Transcription initiation factor TFIID signature 117 132 1.1E-44 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 DFR85_10805 b5bb84cedd04eeb5ef89819e24bf1731 187 PRINTS PR00686 Transcription initiation factor TFIID signature 46 64 1.1E-44 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 DFR85_10805 b5bb84cedd04eeb5ef89819e24bf1731 187 PRINTS PR00686 Transcription initiation factor TFIID signature 94 110 1.1E-44 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 DFR85_10805 b5bb84cedd04eeb5ef89819e24bf1731 187 PRINTS PR00686 Transcription initiation factor TFIID signature 27 46 1.1E-44 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 DFR85_10805 b5bb84cedd04eeb5ef89819e24bf1731 187 PRINTS PR00686 Transcription initiation factor TFIID signature 136 152 1.1E-44 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 DFR85_10805 b5bb84cedd04eeb5ef89819e24bf1731 187 SUPERFAMILY SSF55945 2 86 4.4E-28 T 31-10-2018 DFR85_10805 b5bb84cedd04eeb5ef89819e24bf1731 187 Hamap MF_00408 TATA-box-binding protein [tbp]. 1 176 36.188 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 DFR85_10805 b5bb84cedd04eeb5ef89819e24bf1731 187 Gene3D G3DSA:3.30.310.10 90 179 7.7E-38 T 31-10-2018 IPR012295 TBP domain superfamily DFR85_10805 b5bb84cedd04eeb5ef89819e24bf1731 187 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 2 82 3.4E-27 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 DFR85_10805 b5bb84cedd04eeb5ef89819e24bf1731 187 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 92 172 1.9E-30 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 DFR85_10805 b5bb84cedd04eeb5ef89819e24bf1731 187 SUPERFAMILY SSF55945 88 176 2.83E-31 T 31-10-2018 DFR85_10805 b5bb84cedd04eeb5ef89819e24bf1731 187 Gene3D G3DSA:3.30.310.10 8 89 5.5E-33 T 31-10-2018 IPR012295 TBP domain superfamily DFR85_10805 b5bb84cedd04eeb5ef89819e24bf1731 187 ProSitePatterns PS00351 Transcription factor TFIID repeat signature. 121 170 - T 31-10-2018 IPR030491 TATA-box binding protein, conserved site DFR85_07215 debeec129044e3c777c2d8a69482d64a 400 SUPERFAMILY SSF81271 322 395 8.24E-18 T 31-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 DFR85_07215 debeec129044e3c777c2d8a69482d64a 400 Pfam PF02824 TGS domain 332 394 4.9E-14 T 31-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 DFR85_07215 debeec129044e3c777c2d8a69482d64a 400 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 25 43 9.1E-29 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 DFR85_07215 debeec129044e3c777c2d8a69482d64a 400 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 93 111 9.1E-29 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 DFR85_07215 debeec129044e3c777c2d8a69482d64a 400 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 4 24 9.1E-29 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 DFR85_07215 debeec129044e3c777c2d8a69482d64a 400 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 76 91 9.1E-29 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 DFR85_07215 debeec129044e3c777c2d8a69482d64a 400 Gene3D G3DSA:3.10.20.30 320 397 1.5E-31 T 31-10-2018 IPR012675 Beta-grasp domain superfamily DFR85_07215 debeec129044e3c777c2d8a69482d64a 400 Pfam PF01926 50S ribosome-binding GTPase 4 130 4.3E-20 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 DFR85_07215 debeec129044e3c777c2d8a69482d64a 400 Gene3D G3DSA:1.10.8.470 133 219 1.2E-23 T 31-10-2018 DFR85_07215 debeec129044e3c777c2d8a69482d64a 400 SUPERFAMILY SSF52540 2 315 9.35E-68 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_07215 debeec129044e3c777c2d8a69482d64a 400 Pfam PF08438 GTPase of unknown function C-terminal 224 328 2.4E-35 T 31-10-2018 IPR013646 Uncharacterised GTP-binding protein, C-terminal DFR85_10765 3049a031c58ba3bd3c3ab263b7ed3355 299 Gene3D G3DSA:1.10.260.40 119 228 6.2E-12 T 31-10-2018 DFR85_10765 3049a031c58ba3bd3c3ab263b7ed3355 299 SMART SM00530 123 178 5.0E-11 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DFR85_10765 3049a031c58ba3bd3c3ab263b7ed3355 299 Pfam PF01381 Helix-turn-helix 124 172 1.9E-13 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DFR85_10765 3049a031c58ba3bd3c3ab263b7ed3355 299 SUPERFAMILY SSF47413 120 175 1.02E-12 T 31-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 DFR85_10765 3049a031c58ba3bd3c3ab263b7ed3355 299 Hamap MF_00584 Putative HTH-type transcriptional regulatory protein . 1 295 19.732 T 31-10-2018 IPR020886 Transcription regulator HTH, Cro/C1-type DNA-binding GO:0003700|GO:0006355 DFR85_06385 1d32052331fa47108e25e3c41596b590 317 Gene3D G3DSA:3.40.50.720 109 279 9.6E-58 T 31-10-2018 DFR85_06385 1d32052331fa47108e25e3c41596b590 317 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 71 298 7.9E-40 T 31-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 DFR85_06385 1d32052331fa47108e25e3c41596b590 317 Gene3D G3DSA:3.30.1780.10 5 301 9.6E-58 T 31-10-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 DFR85_06385 1d32052331fa47108e25e3c41596b590 317 PIRSF PIRSF001439 1 307 1.3E-44 T 31-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 DFR85_06385 1d32052331fa47108e25e3c41596b590 317 SUPERFAMILY SSF51735 2 306 3.58E-61 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_07100 14cf00605cf09bd63e3d032fb47ca822 263 ProSitePatterns PS00939 Ribosomal protein L1e signature. 112 138 - T 31-10-2018 IPR013000 Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07100 14cf00605cf09bd63e3d032fb47ca822 263 SUPERFAMILY SSF52166 9 257 1.31E-60 T 31-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 DFR85_07100 14cf00605cf09bd63e3d032fb47ca822 263 Pfam PF00573 Ribosomal protein L4/L1 family 23 256 4.4E-32 T 31-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 DFR85_07100 14cf00605cf09bd63e3d032fb47ca822 263 Hamap MF_01328_A 50S ribosomal protein L4 [rplD]. 9 258 39.671 T 31-10-2018 IPR019970 Ribosomal protein L4 GO:0003735|GO:0005840|GO:0006412|GO:0019843 DFR85_07100 14cf00605cf09bd63e3d032fb47ca822 263 Gene3D G3DSA:3.40.1370.10 7 262 3.7E-77 T 31-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 DFR85_07100 14cf00605cf09bd63e3d032fb47ca822 263 TIGRFAM TIGR03672 rpl4p_arch: 50S ribosomal protein uL4 9 257 1.0E-98 T 31-10-2018 IPR019970 Ribosomal protein L4 GO:0003735|GO:0005840|GO:0006412|GO:0019843 DFR85_01055 9e5da21f8b3a3d7721f187fb81d19ba7 108 Pfam PF02416 mttA/Hcf106 family 7 56 4.1E-11 T 31-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 DFR85_01055 9e5da21f8b3a3d7721f187fb81d19ba7 108 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 6 52 2.6E-17 T 31-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 DFR85_10810 0d78a346a795254ae1be6d3900f93b3d 249 TIGRFAM TIGR00024 SbcD_rel_arch: putative phosphoesterase 23 242 2.2E-40 T 31-10-2018 IPR004376 Conserved hypothetical protein CHP00024, phosphoesterase-like DFR85_10810 0d78a346a795254ae1be6d3900f93b3d 249 Gene3D G3DSA:3.60.21.10 20 218 1.1E-11 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like DFR85_10810 0d78a346a795254ae1be6d3900f93b3d 249 Pfam PF00149 Calcineurin-like phosphoesterase 25 144 3.5E-6 T 31-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 DFR85_10810 0d78a346a795254ae1be6d3900f93b3d 249 SUPERFAMILY SSF56300 25 240 8.44E-15 T 31-10-2018 DFR85_10810 0d78a346a795254ae1be6d3900f93b3d 249 PIRSF PIRSF000887 2 248 1.0E-67 T 31-10-2018 IPR024173 Phosphoesterase, MJ0037 DFR85_10180 4b03d671e938900972d7a2cea37fc02b 336 Hamap MF_00280 50S ribosomal protein L10 [rpl10]. 10 287 32.322 T 31-10-2018 IPR022909 50S ribosomal protein L10, archaea DFR85_10180 4b03d671e938900972d7a2cea37fc02b 336 Gene3D G3DSA:3.30.70.1730 24 212 2.7E-57 T 31-10-2018 DFR85_10180 4b03d671e938900972d7a2cea37fc02b 336 SUPERFAMILY SSF160369 12 142 1.96E-23 T 31-10-2018 DFR85_10180 4b03d671e938900972d7a2cea37fc02b 336 Pfam PF00466 Ribosomal protein L10 13 102 1.2E-23 T 31-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 DFR85_10180 4b03d671e938900972d7a2cea37fc02b 336 Gene3D G3DSA:3.90.105.20 111 190 2.7E-57 T 31-10-2018 DFR85_09245 6472ee0899623cf9a0e63166b96a7a5b 45 Pfam PF01402 Ribbon-helix-helix protein, copG family 5 43 1.5E-7 T 31-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 DFR85_09245 6472ee0899623cf9a0e63166b96a7a5b 45 SUPERFAMILY SSF47598 4 43 4.52E-8 T 31-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 DFR85_06990 35f73474656747476ee374262c8554e8 466 Pfam PF00344 SecY translocase 75 445 2.2E-56 T 31-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 DFR85_06990 35f73474656747476ee374262c8554e8 466 Hamap MF_01465 Protein translocase subunit SecY [secY]. 17 461 18.263 T 31-10-2018 IPR026593 Protein translocase subunit SecY DFR85_06990 35f73474656747476ee374262c8554e8 466 Gene3D G3DSA:1.10.3370.10 5 466 2.6E-123 T 31-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 DFR85_06990 35f73474656747476ee374262c8554e8 466 PIRSF PIRSF004557 4 466 7.9E-95 T 31-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 DFR85_06990 35f73474656747476ee374262c8554e8 466 ProSitePatterns PS00756 Protein secY signature 2. 164 182 - T 31-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 DFR85_06990 35f73474656747476ee374262c8554e8 466 Pfam PF10559 Plug domain of Sec61p 39 74 7.8E-8 T 31-10-2018 IPR019561 Translocon Sec61/SecY, plug domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 DFR85_06990 35f73474656747476ee374262c8554e8 466 SUPERFAMILY SSF103491 5 450 1.57E-89 T 31-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 DFR85_06990 35f73474656747476ee374262c8554e8 466 ProSitePatterns PS00755 Protein secY signature 1. 75 94 - T 31-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 DFR85_07695 9dfaa1888d50cc85d1206b2da351041b 471 Pfam PF02637 GatB domain 323 469 1.8E-36 T 31-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 DFR85_07695 9dfaa1888d50cc85d1206b2da351041b 471 Gene3D G3DSA:1.10.10.410 410 470 3.8E-14 T 31-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal DFR85_07695 9dfaa1888d50cc85d1206b2da351041b 471 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 1 470 33.169 T 31-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 DFR85_07695 9dfaa1888d50cc85d1206b2da351041b 471 Pfam PF02934 GatB/GatE catalytic domain 3 283 1.5E-101 T 31-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 DFR85_07695 9dfaa1888d50cc85d1206b2da351041b 471 SMART SM00845 323 469 8.1E-44 T 31-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 DFR85_07695 9dfaa1888d50cc85d1206b2da351041b 471 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 146 160 - T 31-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 DFR85_07695 9dfaa1888d50cc85d1206b2da351041b 471 Gene3D G3DSA:1.10.150.380 292 409 1.8E-28 T 31-10-2018 DFR85_07695 9dfaa1888d50cc85d1206b2da351041b 471 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 3 469 5.3E-158 T 31-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 DFR85_07695 9dfaa1888d50cc85d1206b2da351041b 471 SUPERFAMILY SSF89095 292 398 8.24E-27 T 31-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 DFR85_07695 9dfaa1888d50cc85d1206b2da351041b 471 SUPERFAMILY SSF55931 2 291 2.88E-100 T 31-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 DFR85_07205 469bad9e5d295e077b90c25d7fb7c291 148 Gene3D G3DSA:3.30.1440.10 1 148 2.2E-36 T 31-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07205 469bad9e5d295e077b90c25d7fb7c291 148 Pfam PF01877 RNA binding 5 123 1.9E-26 T 31-10-2018 IPR002739 Uncharacterised protein family UPF0201 DFR85_07205 469bad9e5d295e077b90c25d7fb7c291 148 SUPERFAMILY SSF55282 4 140 9.71E-32 T 31-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_12055 3648b3440e6683c98fb7fa80c39472d5 346 Pfam PF00483 Nucleotidyl transferase 2 231 3.9E-49 T 31-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 DFR85_12055 3648b3440e6683c98fb7fa80c39472d5 346 Gene3D G3DSA:2.160.10.10 241 326 5.8E-10 T 31-10-2018 DFR85_12055 3648b3440e6683c98fb7fa80c39472d5 346 SUPERFAMILY SSF53448 1 299 2.58E-76 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_12055 3648b3440e6683c98fb7fa80c39472d5 346 TIGRFAM TIGR01208 rmlA_long: glucose-1-phosphate thymidylyltransferase 2 345 2.9E-131 T 31-10-2018 IPR005908 Glucose-1-phosphate thymidylyltransferase, long form DFR85_12055 3648b3440e6683c98fb7fa80c39472d5 346 Gene3D G3DSA:3.90.550.10 1 240 1.4E-69 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_01215 161f6f36b72dc104573feb0b8dae7e2d 393 Gene3D G3DSA:3.90.1300.10 2 391 5.1E-105 T 31-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DFR85_01215 161f6f36b72dc104573feb0b8dae7e2d 393 Pfam PF01425 Amidase 260 382 1.5E-16 T 31-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DFR85_01215 161f6f36b72dc104573feb0b8dae7e2d 393 Pfam PF01425 Amidase 21 193 6.2E-64 T 31-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DFR85_01215 161f6f36b72dc104573feb0b8dae7e2d 393 SUPERFAMILY SSF75304 4 388 1.96E-105 T 31-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DFR85_01215 161f6f36b72dc104573feb0b8dae7e2d 393 ProSitePatterns PS00571 Amidases signature. 108 139 - T 31-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 DFR85_09285 e7cee17a6e3691ff041db913fbb24fd8 89 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 4 81 6.2E-19 T 31-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 DFR85_09285 e7cee17a6e3691ff041db913fbb24fd8 89 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 3 81 16.625 T 31-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 DFR85_09285 e7cee17a6e3691ff041db913fbb24fd8 89 Gene3D G3DSA:3.30.1280.10 1 89 7.7E-32 T 31-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 DFR85_09285 e7cee17a6e3691ff041db913fbb24fd8 89 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 3 83 4.2E-11 T 31-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 DFR85_09285 e7cee17a6e3691ff041db913fbb24fd8 89 SUPERFAMILY SSF82697 2 79 6.1E-18 T 31-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 DFR85_09285 e7cee17a6e3691ff041db913fbb24fd8 89 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 17 80 4.0E-5 T 31-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 DFR85_15145 58da6e2310df4c2f56ff1a31acb863ae 356 Gene3D G3DSA:3.20.20.140 12 342 1.0E-30 T 31-10-2018 DFR85_15145 58da6e2310df4c2f56ff1a31acb863ae 356 Pfam PF04909 Amidohydrolase 15 333 3.2E-37 T 31-10-2018 IPR006680 Amidohydrolase-related GO:0016787 DFR85_15145 58da6e2310df4c2f56ff1a31acb863ae 356 SUPERFAMILY SSF51556 13 333 3.78E-32 T 31-10-2018 IPR032466 Metal-dependent hydrolase DFR85_08750 223a5c1ac0531592b62d987e52d1b0ca 563 Gene3D G3DSA:2.40.240.10 415 503 3.6E-35 T 31-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 DFR85_08750 223a5c1ac0531592b62d987e52d1b0ca 563 Hamap MF_02076 Glutamate--tRNA ligase [gltX]. 7 561 33.708 T 31-10-2018 IPR004526 Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 DFR85_08750 223a5c1ac0531592b62d987e52d1b0ca 563 PRINTS PR00987 Glutamyl-tRNA synthetase signature 295 303 1.3E-22 T 31-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 DFR85_08750 223a5c1ac0531592b62d987e52d1b0ca 563 PRINTS PR00987 Glutamyl-tRNA synthetase signature 129 142 1.3E-22 T 31-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 DFR85_08750 223a5c1ac0531592b62d987e52d1b0ca 563 PRINTS PR00987 Glutamyl-tRNA synthetase signature 279 289 1.3E-22 T 31-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 DFR85_08750 223a5c1ac0531592b62d987e52d1b0ca 563 PRINTS PR00987 Glutamyl-tRNA synthetase signature 114 125 1.3E-22 T 31-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 DFR85_08750 223a5c1ac0531592b62d987e52d1b0ca 563 PRINTS PR00987 Glutamyl-tRNA synthetase signature 100 112 1.3E-22 T 31-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 DFR85_08750 223a5c1ac0531592b62d987e52d1b0ca 563 Gene3D G3DSA:3.40.50.620 55 407 1.6E-108 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR85_08750 223a5c1ac0531592b62d987e52d1b0ca 563 SUPERFAMILY SSF50715 406 552 1.31E-19 T 31-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 DFR85_08750 223a5c1ac0531592b62d987e52d1b0ca 563 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 406 549 1.2E-18 T 31-10-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 DFR85_08750 223a5c1ac0531592b62d987e52d1b0ca 563 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 96 403 1.7E-83 T 31-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 DFR85_08750 223a5c1ac0531592b62d987e52d1b0ca 563 TIGRFAM TIGR00463 gltX_arch: glutamate--tRNA ligase 4 562 4.8E-159 T 31-10-2018 IPR004526 Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 DFR85_08750 223a5c1ac0531592b62d987e52d1b0ca 563 Gene3D G3DSA:2.40.240.100 408 562 3.6E-35 T 31-10-2018 DFR85_08750 223a5c1ac0531592b62d987e52d1b0ca 563 SUPERFAMILY SSF52374 96 412 3.49E-87 T 31-10-2018 DFR85_02410 ec114cbb0a3ffaf6b630010a2246dd44 127 Pfam PF05942 Archaeal PaREP1/PaREP8 family 15 122 1.1E-29 T 31-10-2018 IPR010268 Archaeal PaREP1 DFR85_02410 ec114cbb0a3ffaf6b630010a2246dd44 127 Gene3D G3DSA:1.20.120.330 11 127 8.8E-45 T 31-10-2018 DFR85_07320 17182ec7273bb016c6099f6ec1d498d7 230 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 3 91 1.9E-9 T 31-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain DFR85_07320 17182ec7273bb016c6099f6ec1d498d7 230 Gene3D G3DSA:3.30.70.2210 153 229 1.1E-5 T 31-10-2018 DFR85_07320 17182ec7273bb016c6099f6ec1d498d7 230 SUPERFAMILY SSF54534 3 150 3.14E-33 T 31-10-2018 DFR85_07320 17182ec7273bb016c6099f6ec1d498d7 230 Gene3D G3DSA:3.10.50.40 5 148 9.4E-45 T 31-10-2018 DFR85_07320 17182ec7273bb016c6099f6ec1d498d7 230 Gene3D G3DSA:2.40.10.330 90 134 9.4E-45 T 31-10-2018 DFR85_08985 4a0a0f15bd7a45f3a51482c8e09c538c 239 Pfam PF01026 TatD related DNase 3 238 2.4E-52 T 31-10-2018 IPR001130 TatD family GO:0016788 DFR85_08985 4a0a0f15bd7a45f3a51482c8e09c538c 239 SUPERFAMILY SSF51556 2 238 4.77E-54 T 31-10-2018 IPR032466 Metal-dependent hydrolase DFR85_08985 4a0a0f15bd7a45f3a51482c8e09c538c 239 Gene3D G3DSA:3.20.20.140 1 239 1.8E-64 T 31-10-2018 DFR85_08985 4a0a0f15bd7a45f3a51482c8e09c538c 239 PIRSF PIRSF005902 1 239 1.0E-53 T 31-10-2018 IPR001130 TatD family GO:0016788 DFR85_10885 d75f2e217feb523cd288b7d648c285cf 89 Pfam PF01918 Alba 7 66 2.2E-13 T 31-10-2018 IPR002775 DNA/RNA-binding protein Alba-like GO:0003676 DFR85_10885 d75f2e217feb523cd288b7d648c285cf 89 SUPERFAMILY SSF82704 4 87 3.4E-18 T 31-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 DFR85_10885 d75f2e217feb523cd288b7d648c285cf 89 ProDom PD010497 ALBA DNA-BINDING DNA/RNA-BINDING RNA-BINDING ACETYLATION 3D-STRUCTURE DNA CONDENSATION AF1 SSO10B 10 89 6.0E-23 T 31-10-2018 DFR85_10885 d75f2e217feb523cd288b7d648c285cf 89 Gene3D G3DSA:3.30.110.20 1 89 6.9E-32 T 31-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 DFR85_14455 8759a4691ac1f713df38c5e7a772c6fb 278 PRINTS PR00069 Aldo-keto reductase signature 48 72 3.6E-18 T 31-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 DFR85_14455 8759a4691ac1f713df38c5e7a772c6fb 278 PRINTS PR00069 Aldo-keto reductase signature 102 120 3.6E-18 T 31-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 DFR85_14455 8759a4691ac1f713df38c5e7a772c6fb 278 PRINTS PR00069 Aldo-keto reductase signature 133 150 3.6E-18 T 31-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 DFR85_14455 8759a4691ac1f713df38c5e7a772c6fb 278 Pfam PF00248 Aldo/keto reductase family 35 276 1.5E-63 T 31-10-2018 IPR023210 NADP-dependent oxidoreductase domain DFR85_14455 8759a4691ac1f713df38c5e7a772c6fb 278 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 133 150 - T 31-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 DFR85_14455 8759a4691ac1f713df38c5e7a772c6fb 278 SUPERFAMILY SSF51430 1 277 1.44E-82 T 31-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily DFR85_14455 8759a4691ac1f713df38c5e7a772c6fb 278 PIRSF PIRSF000097 7 124 8.4E-19 T 31-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 DFR85_14455 8759a4691ac1f713df38c5e7a772c6fb 278 PIRSF PIRSF000097 121 277 4.9E-18 T 31-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 DFR85_14455 8759a4691ac1f713df38c5e7a772c6fb 278 Gene3D G3DSA:3.20.20.100 1 277 1.5E-83 T 31-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily DFR85_13240 1ea1b6dc1ce99f99e6b43c1e96baf93d 130 Pfam PF01850 PIN domain 19 115 1.1E-9 T 31-10-2018 IPR002716 PIN domain DFR85_13240 1ea1b6dc1ce99f99e6b43c1e96baf93d 130 Gene3D G3DSA:3.40.50.1010 12 119 4.8E-10 T 31-10-2018 DFR85_13240 1ea1b6dc1ce99f99e6b43c1e96baf93d 130 SUPERFAMILY SSF88723 19 118 1.14E-11 T 31-10-2018 IPR029060 PIN-like domain superfamily DFR85_09940 ad0e7468f62251464e8347a00982a8a4 421 SMART SM01027 231 341 1.8E-33 T 31-10-2018 IPR022712 Beta-Casp domain DFR85_09940 ad0e7468f62251464e8347a00982a8a4 421 Pfam PF16661 Metallo-beta-lactamase superfamily domain 25 177 5.9E-11 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR85_09940 ad0e7468f62251464e8347a00982a8a4 421 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 354 413 1.7E-9 T 31-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain DFR85_09940 ad0e7468f62251464e8347a00982a8a4 421 Pfam PF10996 Beta-Casp domain 235 341 9.9E-16 T 31-10-2018 IPR022712 Beta-Casp domain DFR85_09940 ad0e7468f62251464e8347a00982a8a4 421 Gene3D G3DSA:3.60.15.10 8 400 1.5E-97 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR85_09940 ad0e7468f62251464e8347a00982a8a4 421 SUPERFAMILY SSF56281 4 421 1.9E-99 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR85_09940 ad0e7468f62251464e8347a00982a8a4 421 SMART SM00849 15 197 3.8E-13 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR85_09940 ad0e7468f62251464e8347a00982a8a4 421 Gene3D G3DSA:3.40.50.10890 199 367 1.5E-97 T 31-10-2018 DFR85_08680 d31161ac1ec366d4a3a823d8bc7c939c 117 Gene3D G3DSA:1.10.260.40 6 115 7.8E-5 T 31-10-2018 DFR85_08680 d31161ac1ec366d4a3a823d8bc7c939c 117 SUPERFAMILY SSF47413 23 60 5.93E-5 T 31-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 DFR85_08680 d31161ac1ec366d4a3a823d8bc7c939c 117 Pfam PF01381 Helix-turn-helix 23 56 1.1E-5 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DFR85_12740 c2a24432aeb9eddd87816beac7ea9860 323 SMART SM00382 26 209 1.0E-12 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_12740 c2a24432aeb9eddd87816beac7ea9860 323 Gene3D G3DSA:3.40.50.300 1 235 5.2E-77 T 31-10-2018 DFR85_12740 c2a24432aeb9eddd87816beac7ea9860 323 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DFR85_12740 c2a24432aeb9eddd87816beac7ea9860 323 SUPERFAMILY SSF50331 236 307 2.31E-6 T 31-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal DFR85_12740 c2a24432aeb9eddd87816beac7ea9860 323 SUPERFAMILY SSF52540 1 240 8.11E-82 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_12740 c2a24432aeb9eddd87816beac7ea9860 323 Pfam PF00005 ABC transporter 17 159 4.2E-35 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR85_14460 1867a82ca193d7ecbbcab4fcc8b3d734 180 SUPERFAMILY SSF54637 30 179 1.83E-41 T 31-10-2018 IPR029069 HotDog domain superfamily DFR85_14460 1867a82ca193d7ecbbcab4fcc8b3d734 180 Gene3D G3DSA:3.10.129.10 24 180 5.6E-44 T 31-10-2018 DFR85_14460 1867a82ca193d7ecbbcab4fcc8b3d734 180 Pfam PF01575 MaoC like domain 39 147 3.4E-16 T 31-10-2018 IPR002539 MaoC-like dehydratase domain DFR85_12085 592aa088189f34b237f7d3abf6d563be 287 Gene3D G3DSA:3.30.70.1900 119 284 7.6E-45 T 31-10-2018 DFR85_12085 592aa088189f34b237f7d3abf6d563be 287 Pfam PF10040 CRISPR-associated endoribonuclease Cas6 133 275 1.1E-14 T 31-10-2018 IPR019267 CRISPR-associated protein Cas6, C-terminal DFR85_12085 592aa088189f34b237f7d3abf6d563be 287 Gene3D G3DSA:3.30.70.2990 1 118 2.1E-24 T 31-10-2018 DFR85_10720 7a72f951dbea238988068a08b269db8b 829 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 118 785 4.4E-230 T 31-10-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 DFR85_10720 7a72f951dbea238988068a08b269db8b 829 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 115 773 5.3E-117 T 31-10-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 DFR85_10720 7a72f951dbea238988068a08b269db8b 829 Pfam PF03477 ATP cone domain 13 87 5.2E-7 T 31-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 DFR85_10720 7a72f951dbea238988068a08b269db8b 829 PRINTS PR01183 Ribonucleotide reductase large chain signature 278 297 4.1E-41 T 31-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 DFR85_10720 7a72f951dbea238988068a08b269db8b 829 PRINTS PR01183 Ribonucleotide reductase large chain signature 545 568 4.1E-41 T 31-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 DFR85_10720 7a72f951dbea238988068a08b269db8b 829 PRINTS PR01183 Ribonucleotide reductase large chain signature 479 502 4.1E-41 T 31-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 DFR85_10720 7a72f951dbea238988068a08b269db8b 829 PRINTS PR01183 Ribonucleotide reductase large chain signature 629 656 4.1E-41 T 31-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 DFR85_10720 7a72f951dbea238988068a08b269db8b 829 PRINTS PR01183 Ribonucleotide reductase large chain signature 517 539 4.1E-41 T 31-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 DFR85_10720 7a72f951dbea238988068a08b269db8b 829 Pfam PF02867 Ribonucleotide reductase, barrel domain 198 775 2.0E-185 T 31-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 DFR85_10720 7a72f951dbea238988068a08b269db8b 829 SUPERFAMILY SSF51998 197 788 1.01E-151 T 31-10-2018 DFR85_10720 7a72f951dbea238988068a08b269db8b 829 SUPERFAMILY SSF48168 18 194 4.45E-28 T 31-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 DFR85_10720 7a72f951dbea238988068a08b269db8b 829 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 112 195 2.4E-27 T 31-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 DFR85_12065 0e2963abe8816f1a530398670194d275 380 Gene3D G3DSA:1.20.1250.20 192 373 1.2E-14 T 31-10-2018 DFR85_12065 0e2963abe8816f1a530398670194d275 380 SUPERFAMILY SSF103473 12 371 2.22E-25 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_12065 0e2963abe8816f1a530398670194d275 380 Gene3D G3DSA:1.20.1250.20 6 176 1.1E-7 T 31-10-2018 DFR85_12065 0e2963abe8816f1a530398670194d275 380 Pfam PF07690 Major Facilitator Superfamily 194 372 2.9E-13 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_04775 7f0211d5b7bde2d7b809fbb895215536 298 Pfam PF12686 Protein of unknown function (DUF3800) 24 274 5.6E-10 T 31-10-2018 IPR024524 Protein of unknown function DUF3800 DFR85_00545 5c00f94360040738238a7fdceaafc399 221 Pfam PF00881 Nitroreductase family 7 174 2.0E-24 T 31-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 DFR85_00545 5c00f94360040738238a7fdceaafc399 221 Gene3D G3DSA:3.40.109.10 1 177 1.4E-43 T 31-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 DFR85_00545 5c00f94360040738238a7fdceaafc399 221 TIGRFAM TIGR02476 BluB: 5,6-dimethylbenzimidazole synthase 3 198 1.3E-71 T 31-10-2018 IPR012825 5,6-dimethylbenzimidazole synthase BluB KEGG: 00740+1.13.11.79|MetaCyc: PWY-5523 DFR85_00545 5c00f94360040738238a7fdceaafc399 221 SUPERFAMILY SSF55469 1 213 5.23E-47 T 31-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 DFR85_03060 88fb9e745f123d69b9cd65a923710413 267 Pfam PF00155 Aminotransferase class I and II 89 163 7.1E-5 T 31-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 DFR85_03060 88fb9e745f123d69b9cd65a923710413 267 SUPERFAMILY SSF53383 89 261 3.92E-21 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase DFR85_03060 88fb9e745f123d69b9cd65a923710413 267 Gene3D G3DSA:3.40.640.10 83 267 2.2E-17 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR85_12655 b3b36b2012dfb0d7ab87cd02322e71a0 481 Gene3D G3DSA:1.20.1250.20 13 455 1.0E-104 T 31-10-2018 DFR85_12655 b3b36b2012dfb0d7ab87cd02322e71a0 481 ProSitePatterns PS00216 Sugar transport proteins signature 1. 306 322 - T 31-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DFR85_12655 b3b36b2012dfb0d7ab87cd02322e71a0 481 PRINTS PR00171 Sugar transporter signature 32 42 1.6E-18 T 31-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 DFR85_12655 b3b36b2012dfb0d7ab87cd02322e71a0 481 PRINTS PR00171 Sugar transporter signature 376 388 1.6E-18 T 31-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 DFR85_12655 b3b36b2012dfb0d7ab87cd02322e71a0 481 PRINTS PR00171 Sugar transporter signature 115 134 1.6E-18 T 31-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 DFR85_12655 b3b36b2012dfb0d7ab87cd02322e71a0 481 PRINTS PR00171 Sugar transporter signature 353 374 1.6E-18 T 31-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 DFR85_12655 b3b36b2012dfb0d7ab87cd02322e71a0 481 PRINTS PR00171 Sugar transporter signature 262 272 1.6E-18 T 31-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 DFR85_12655 b3b36b2012dfb0d7ab87cd02322e71a0 481 SUPERFAMILY SSF103473 12 449 2.22E-68 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_12655 b3b36b2012dfb0d7ab87cd02322e71a0 481 Pfam PF00083 Sugar (and other) transporter 25 452 2.9E-87 T 31-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 DFR85_12655 b3b36b2012dfb0d7ab87cd02322e71a0 481 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 19 447 2.2E-81 T 31-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 DFR85_12655 b3b36b2012dfb0d7ab87cd02322e71a0 481 ProSitePatterns PS00217 Sugar transport proteins signature 2. 120 145 - T 31-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DFR85_08300 dc5c5f24c840800b31e590361305f305 171 Gene3D G3DSA:3.40.50.300 5 168 1.1E-8 T 31-10-2018 DFR85_08300 dc5c5f24c840800b31e590361305f305 171 SUPERFAMILY SSF52540 6 148 2.47E-8 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_11675 2e952f949352ec871ed03f66e0c39a6f 147 Pfam PF00293 NUDIX domain 9 115 1.8E-7 T 31-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 DFR85_11675 2e952f949352ec871ed03f66e0c39a6f 147 ProSitePatterns PS00893 Nudix box signature. 34 55 - T 31-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 DFR85_11675 2e952f949352ec871ed03f66e0c39a6f 147 Gene3D G3DSA:3.90.79.10 4 144 1.9E-30 T 31-10-2018 DFR85_11675 2e952f949352ec871ed03f66e0c39a6f 147 SUPERFAMILY SSF55811 7 126 1.9E-17 T 31-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 DFR85_07700 a81837842c4d1df95959f9d538d22f85 131 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 58 98 - T 31-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 DFR85_07700 a81837842c4d1df95959f9d538d22f85 131 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 10 130 1.6E-46 T 31-10-2018 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-6798695|Reactome: R-HSA-73614 DFR85_07700 a81837842c4d1df95959f9d538d22f85 131 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 8 102 5.3E-18 T 31-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain DFR85_07700 a81837842c4d1df95959f9d538d22f85 131 SUPERFAMILY SSF53927 7 129 2.34E-44 T 31-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 DFR85_07700 a81837842c4d1df95959f9d538d22f85 131 Gene3D G3DSA:3.40.140.10 2 131 4.2E-52 T 31-10-2018 DFR85_10185 4bfac1bc5e29f7b550c63a5f744e4b72 103 Gene3D G3DSA:1.10.10.1410 1 58 3.5E-27 T 31-10-2018 IPR038716 Ribosomal protein P1/P2, N-terminal domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_10185 4bfac1bc5e29f7b550c63a5f744e4b72 103 Hamap MF_01478 50S ribosomal protein L12 [rpl12]. 1 100 12.969 T 31-10-2018 IPR027534 Ribosomal protein L12 family GO:0003735|GO:0005622|GO:0005840|GO:0006414 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_10185 4bfac1bc5e29f7b550c63a5f744e4b72 103 TIGRFAM TIGR03685 ribo_P1_arch: 50S ribosomal protein P1 1 103 8.9E-43 T 31-10-2018 IPR022295 Ribosomal protein L12, archaea GO:0003735|GO:0005840|GO:0006414 DFR85_10185 4bfac1bc5e29f7b550c63a5f744e4b72 103 Pfam PF00428 60s Acidic ribosomal protein 17 102 5.5E-20 T 31-10-2018 DFR85_09255 849eeef81643b8973f256e21cbc2f3ea 321 Pfam PF00586 AIR synthase related protein, N-terminal domain 50 152 7.7E-17 T 31-10-2018 IPR016188 PurM-like, N-terminal domain DFR85_09255 849eeef81643b8973f256e21cbc2f3ea 321 SUPERFAMILY SSF55326 2 156 4.36E-35 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily DFR85_09255 849eeef81643b8973f256e21cbc2f3ea 321 Gene3D G3DSA:3.30.1330.10 2 157 1.3E-45 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily DFR85_09255 849eeef81643b8973f256e21cbc2f3ea 321 Gene3D G3DSA:3.90.650.10 158 316 7.4E-44 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily DFR85_09255 849eeef81643b8973f256e21cbc2f3ea 321 SUPERFAMILY SSF56042 158 311 5.93E-37 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily DFR85_09255 849eeef81643b8973f256e21cbc2f3ea 321 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 2 305 1.7E-91 T 31-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 DFR85_09255 849eeef81643b8973f256e21cbc2f3ea 321 Pfam PF02769 AIR synthase related protein, C-terminal domain 162 311 7.3E-25 T 31-10-2018 IPR010918 PurM-like, C-terminal domain DFR85_11215 b17f0a1f5a89c19f1c84d2c29344fc50 183 Pfam PF02834 LigT like Phosphoesterase 14 87 4.0E-15 T 31-10-2018 IPR014051 Phosphoesterase, HXTX DFR85_11215 b17f0a1f5a89c19f1c84d2c29344fc50 183 Pfam PF02834 LigT like Phosphoesterase 96 173 6.3E-10 T 31-10-2018 IPR014051 Phosphoesterase, HXTX DFR85_11215 b17f0a1f5a89c19f1c84d2c29344fc50 183 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 1 178 4.3E-44 T 31-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 DFR85_11215 b17f0a1f5a89c19f1c84d2c29344fc50 183 SUPERFAMILY SSF55144 1 179 4.71E-37 T 31-10-2018 IPR009097 Cyclic phosphodiesterase DFR85_11215 b17f0a1f5a89c19f1c84d2c29344fc50 183 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 1 181 25.944 T 31-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 DFR85_11215 b17f0a1f5a89c19f1c84d2c29344fc50 183 Gene3D G3DSA:3.90.1140.10 1 181 5.4E-50 T 31-10-2018 DFR85_12485 96371db15a32fac3b025d6e456b153d3 114 SUPERFAMILY SSF75169 4 114 1.73E-5 T 31-10-2018 IPR027396 DsrEFH-like DFR85_12485 96371db15a32fac3b025d6e456b153d3 114 Gene3D G3DSA:3.40.1260.10 1 114 2.1E-13 T 31-10-2018 IPR027396 DsrEFH-like DFR85_12485 96371db15a32fac3b025d6e456b153d3 114 Pfam PF02635 DsrE/DsrF-like family 3 114 1.6E-6 T 31-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein DFR85_00770 035f5402e0e870f593668516c3cd1ad3 138 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 10 136 1.6E-22 T 31-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 DFR85_00770 035f5402e0e870f593668516c3cd1ad3 138 SUPERFAMILY SSF55620 10 137 3.45E-31 T 31-10-2018 DFR85_00770 035f5402e0e870f593668516c3cd1ad3 138 Gene3D G3DSA:3.30.479.10 1 137 6.0E-27 T 31-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 DFR85_01375 b987e1701fbc6b200fe564143ed51e15 219 SUPERFAMILY SSF75217 2 217 6.37E-51 T 31-10-2018 IPR029028 Alpha/beta knot methyltransferases DFR85_01375 b987e1701fbc6b200fe564143ed51e15 219 Pfam PF03587 EMG1/NEP1 methyltransferase 6 212 5.7E-40 T 31-10-2018 IPR005304 Ribosomal biogenesis, methyltransferase, EMG1/NEP1 GO:0008168 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 DFR85_01375 b987e1701fbc6b200fe564143ed51e15 219 Hamap MF_00554 Ribosomal RNA small subunit methyltransferase Nep1 [nep1]. 3 215 32.228 T 31-10-2018 IPR023503 Ribosome biogenesis methyltransferase NEP1, archaea GO:0008168 DFR85_01375 b987e1701fbc6b200fe564143ed51e15 219 Gene3D G3DSA:3.40.1280.10 1 217 1.3E-66 T 31-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal DFR85_08920 1c5f9ef3a30323c087b207f715e19735 284 TIGRFAM TIGR04336 AmmeMemoSam_B: AmmeMemoRadiSam system protein B 3 281 1.6E-97 T 31-10-2018 DFR85_08920 1c5f9ef3a30323c087b207f715e19735 284 Gene3D G3DSA:3.40.830.10 1 282 3.7E-70 T 31-10-2018 DFR85_08920 1c5f9ef3a30323c087b207f715e19735 284 Hamap MF_00055 MEMO1 family protein . 1 283 61.347 T 31-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 DFR85_08920 1c5f9ef3a30323c087b207f715e19735 284 Pfam PF01875 Memo-like protein 5 280 7.2E-91 T 31-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 DFR85_10570 358ec14ae9b1ed8fd69887622ac39858 201 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 3 197 22.483 T 31-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 DFR85_10570 358ec14ae9b1ed8fd69887622ac39858 201 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 5 192 7.8E-33 T 31-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 DFR85_10570 358ec14ae9b1ed8fd69887622ac39858 201 SUPERFAMILY SSF51366 3 195 4.08E-33 T 31-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 DFR85_10570 358ec14ae9b1ed8fd69887622ac39858 201 Gene3D G3DSA:3.20.20.70 3 198 7.7E-31 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_08385 1b406bf9bbe2ab9e5f1e0bb82af71b8e 195 SUPERFAMILY SSF53474 4 194 1.34E-38 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold DFR85_08385 1b406bf9bbe2ab9e5f1e0bb82af71b8e 195 PRINTS PR00111 Alpha/beta hydrolase fold signature 106 119 2.3E-5 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 DFR85_08385 1b406bf9bbe2ab9e5f1e0bb82af71b8e 195 PRINTS PR00111 Alpha/beta hydrolase fold signature 52 67 2.3E-5 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 DFR85_08385 1b406bf9bbe2ab9e5f1e0bb82af71b8e 195 Pfam PF00561 alpha/beta hydrolase fold 25 127 4.9E-15 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 DFR85_08385 1b406bf9bbe2ab9e5f1e0bb82af71b8e 195 Gene3D G3DSA:3.40.50.1820 1 195 7.4E-41 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold DFR85_06845 d499463e3d36a703f699c3f5335a53cf 127 Pfam PF03966 Trm112p-like protein 2 85 5.8E-16 T 31-10-2018 IPR005651 Trm112-like DFR85_06845 d499463e3d36a703f699c3f5335a53cf 127 SUPERFAMILY SSF158997 57 102 6.28E-12 T 31-10-2018 DFR85_07825 74523c2f21d9e2d51977bc01b578620d 243 TIGRFAM TIGR00425 CBF5: putative rRNA pseudouridine synthase 1 243 3.2E-89 T 31-10-2018 IPR004802 tRNA pseudouridine synthase B family GO:0006396 Reactome: R-HSA-171319|Reactome: R-HSA-6790901 DFR85_07825 74523c2f21d9e2d51977bc01b578620d 243 SUPERFAMILY SSF55120 1 157 3.74E-40 T 31-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 DFR85_07825 74523c2f21d9e2d51977bc01b578620d 243 Pfam PF01472 PUA domain 160 232 3.9E-21 T 31-10-2018 IPR002478 PUA domain GO:0003723 DFR85_07825 74523c2f21d9e2d51977bc01b578620d 243 SUPERFAMILY SSF88697 160 239 1.16E-19 T 31-10-2018 IPR015947 PUA-like superfamily DFR85_07825 74523c2f21d9e2d51977bc01b578620d 243 SMART SM00359 160 233 4.8E-17 T 31-10-2018 IPR002478 PUA domain GO:0003723 DFR85_07825 74523c2f21d9e2d51977bc01b578620d 243 Gene3D G3DSA:3.30.2350.10 1 151 1.4E-41 T 31-10-2018 DFR85_07825 74523c2f21d9e2d51977bc01b578620d 243 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 160 227 1.3E-12 T 31-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 DFR85_07825 74523c2f21d9e2d51977bc01b578620d 243 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 91 156 3.4E-23 T 31-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 DFR85_07825 74523c2f21d9e2d51977bc01b578620d 243 Gene3D G3DSA:2.30.130.70 152 243 2.5E-28 T 31-10-2018 DFR85_03980 1936a53eae359f4225a33165fcc623b4 403 Pfam PF13635 Domain of unknown function (DUF4143) 233 348 4.2E-9 T 31-10-2018 IPR025420 Domain of unknown function DUF4143 DFR85_03980 1936a53eae359f4225a33165fcc623b4 403 SUPERFAMILY SSF52540 39 211 1.8E-21 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_03980 1936a53eae359f4225a33165fcc623b4 403 Pfam PF13173 AAA domain 40 161 2.1E-31 T 31-10-2018 DFR85_03980 1936a53eae359f4225a33165fcc623b4 403 Gene3D G3DSA:3.40.50.300 19 100 3.3E-5 T 31-10-2018 DFR85_12305 99fc76e731259968e341485e5d3950e8 344 SUPERFAMILY SSF102114 4 316 1.03E-62 T 31-10-2018 DFR85_12305 99fc76e731259968e341485e5d3950e8 344 SMART SM00729 5 204 8.4E-4 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 DFR85_12305 99fc76e731259968e341485e5d3950e8 344 PIRSF PIRSF037420 1 344 4.0E-91 T 31-10-2018 IPR017200 Coenzyme PQQ synthesis protein E DFR85_12305 99fc76e731259968e341485e5d3950e8 344 Pfam PF04055 Radical SAM superfamily 11 152 2.6E-14 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR85_12305 99fc76e731259968e341485e5d3950e8 344 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 249 335 4.8E-13 T 31-10-2018 IPR023885 4Fe4S-binding SPASM domain DFR85_12305 99fc76e731259968e341485e5d3950e8 344 Pfam PF13353 4Fe-4S single cluster domain 7 117 1.5E-6 T 31-10-2018 DFR85_12305 99fc76e731259968e341485e5d3950e8 344 Pfam PF13186 Iron-sulfur cluster-binding domain 249 308 1.5E-9 T 31-10-2018 IPR023885 4Fe4S-binding SPASM domain DFR85_12305 99fc76e731259968e341485e5d3950e8 344 Gene3D G3DSA:3.20.20.70 5 341 3.6E-46 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_09855 28b15ef1b6f0b3c4e73ce6c8d36e7a75 173 ProSitePatterns PS01257 Ribosomal protein L10e signature. 106 127 - T 31-10-2018 IPR018255 Ribosomal protein L10e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_09855 28b15ef1b6f0b3c4e73ce6c8d36e7a75 173 SUPERFAMILY SSF54686 4 167 5.23E-55 T 31-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 DFR85_09855 28b15ef1b6f0b3c4e73ce6c8d36e7a75 173 PIRSF PIRSF005590 1 173 7.9E-68 T 31-10-2018 IPR001197 Ribosomal protein L10e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_09855 28b15ef1b6f0b3c4e73ce6c8d36e7a75 173 Hamap MF_00448 50S ribosomal protein L10e [rpl10e]. 1 173 35.99 T 31-10-2018 IPR022981 Ribosomal protein L10e, archaea DFR85_09855 28b15ef1b6f0b3c4e73ce6c8d36e7a75 173 Gene3D G3DSA:3.90.1170.10 1 172 1.4E-63 T 31-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 DFR85_09855 28b15ef1b6f0b3c4e73ce6c8d36e7a75 173 Pfam PF00252 Ribosomal protein L16p/L10e 15 165 8.7E-33 T 31-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 DFR85_01350 ab25075db6ee36c464ee8c3f11876c5d 169 Hamap MF_00648 Non-canonical purine NTP phosphatase. 1 169 26.674 T 31-10-2018 IPR002786 Non-canonical purine NTP phosphatase DFR85_01350 ab25075db6ee36c464ee8c3f11876c5d 169 Gene3D G3DSA:3.90.950.10 1 169 8.1E-47 T 31-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like DFR85_01350 ab25075db6ee36c464ee8c3f11876c5d 169 Pfam PF01931 Protein of unknown function DUF84 6 164 4.5E-48 T 31-10-2018 IPR026533 Non-canonical purine NTP phosphatase/PRRC1 DFR85_01350 ab25075db6ee36c464ee8c3f11876c5d 169 SUPERFAMILY SSF52972 1 167 6.1E-42 T 31-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like DFR85_08645 f635542ebc67b41b587fbef78323bc01 188 Gene3D G3DSA:3.90.1530.10 1 87 3.9E-19 T 31-10-2018 DFR85_08645 f635542ebc67b41b587fbef78323bc01 188 SUPERFAMILY SSF110849 3 187 1.7E-31 T 31-10-2018 IPR036086 ParB/Sulfiredoxin superfamily DFR85_08645 f635542ebc67b41b587fbef78323bc01 188 Pfam PF02195 ParB-like nuclease domain 9 69 4.5E-9 T 31-10-2018 IPR003115 ParB/Sulfiredoxin DFR85_08645 f635542ebc67b41b587fbef78323bc01 188 SMART SM00470 1 83 7.0E-4 T 31-10-2018 IPR003115 ParB/Sulfiredoxin DFR85_03990 5c79380f47b603221bd0bb715b0155a8 121 SUPERFAMILY SSF103247 4 119 3.53E-26 T 31-10-2018 IPR035923 TT1751-like domain superfamily DFR85_03990 5c79380f47b603221bd0bb715b0155a8 121 Gene3D G3DSA:3.30.310.70 2 119 4.7E-14 T 31-10-2018 IPR035923 TT1751-like domain superfamily DFR85_03990 5c79380f47b603221bd0bb715b0155a8 121 Pfam PF03625 Domain of unknown function DUF302 31 90 2.0E-13 T 31-10-2018 IPR005180 Domain of unknown function DUF302 DFR85_03090 5a97901b83e0a31a25c50cfda2944bf4 310 Gene3D G3DSA:2.102.10.10 1 117 6.0E-28 T 31-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 DFR85_03090 5a97901b83e0a31a25c50cfda2944bf4 310 SUPERFAMILY SSF50022 20 111 1.31E-25 T 31-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 DFR85_03090 5a97901b83e0a31a25c50cfda2944bf4 310 Gene3D G3DSA:3.30.530.90 122 197 7.1E-6 T 31-10-2018 DFR85_03090 5a97901b83e0a31a25c50cfda2944bf4 310 SUPERFAMILY SSF55961 106 302 6.23E-21 T 31-10-2018 DFR85_03090 5a97901b83e0a31a25c50cfda2944bf4 310 Pfam PF00355 Rieske [2Fe-2S] domain 14 80 1.8E-17 T 31-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DFR85_12965 e5cb2465bf5edf93944173a8e662cd17 401 Pfam PF07282 Putative transposase DNA-binding domain 305 372 1.3E-23 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR85_12965 e5cb2465bf5edf93944173a8e662cd17 401 Pfam PF01385 Probable transposase 181 286 5.0E-20 T 31-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 DFR85_12965 e5cb2465bf5edf93944173a8e662cd17 401 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 255 330 5.8E-15 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR85_13945 1cce6c2fc4acf4424024a5f30b0b3897 197 Pfam PF03358 NADPH-dependent FMN reductase 17 147 1.3E-14 T 31-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 DFR85_13945 1cce6c2fc4acf4424024a5f30b0b3897 197 SUPERFAMILY SSF52218 4 195 7.08E-54 T 31-10-2018 IPR029039 Flavoprotein-like superfamily DFR85_13945 1cce6c2fc4acf4424024a5f30b0b3897 197 Gene3D G3DSA:3.40.50.360 1 196 5.1E-68 T 31-10-2018 IPR029039 Flavoprotein-like superfamily DFR85_13945 1cce6c2fc4acf4424024a5f30b0b3897 197 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 3 194 2.7E-48 T 31-10-2018 IPR010089 Flavoprotein WrbA-like GO:0003955|GO:0010181 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 DFR85_14610 d6b0115f892456f723cc7d9b0e3509b1 654 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 188 282 3.4E-23 T 31-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 DFR85_14610 d6b0115f892456f723cc7d9b0e3509b1 654 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 305 394 2.5E-17 T 31-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 DFR85_14610 d6b0115f892456f723cc7d9b0e3509b1 654 Pfam PF00378 Enoyl-CoA hydratase/isomerase 407 653 1.1E-68 T 31-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 DFR85_14610 d6b0115f892456f723cc7d9b0e3509b1 654 Gene3D G3DSA:1.10.1040.10 301 388 3.1E-22 T 31-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 DFR85_14610 d6b0115f892456f723cc7d9b0e3509b1 654 SUPERFAMILY SSF48179 187 291 1.53E-22 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 DFR85_14610 d6b0115f892456f723cc7d9b0e3509b1 654 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 8 185 1.3E-64 T 31-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 DFR85_14610 d6b0115f892456f723cc7d9b0e3509b1 654 Gene3D G3DSA:1.10.1040.10 190 300 2.6E-24 T 31-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 DFR85_14610 d6b0115f892456f723cc7d9b0e3509b1 654 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 496 516 - T 31-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 DFR85_14610 d6b0115f892456f723cc7d9b0e3509b1 654 Gene3D G3DSA:1.10.12.10 596 654 2.9E-19 T 31-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal DFR85_14610 d6b0115f892456f723cc7d9b0e3509b1 654 SUPERFAMILY SSF52096 396 653 3.92E-85 T 31-10-2018 IPR029045 ClpP/crotonase-like domain superfamily DFR85_14610 d6b0115f892456f723cc7d9b0e3509b1 654 SUPERFAMILY SSF48179 306 405 1.62E-23 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 DFR85_14610 d6b0115f892456f723cc7d9b0e3509b1 654 Gene3D G3DSA:3.90.226.10 389 595 1.1E-70 T 31-10-2018 DFR85_14610 d6b0115f892456f723cc7d9b0e3509b1 654 SUPERFAMILY SSF51735 2 184 4.74E-57 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_14610 d6b0115f892456f723cc7d9b0e3509b1 654 Gene3D G3DSA:3.40.50.720 1 189 1.8E-67 T 31-10-2018 DFR85_15455 dea5c3c79a84f3d647a4478d353bbb2b 291 SUPERFAMILY SSF52540 3 220 1.41E-52 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_15455 dea5c3c79a84f3d647a4478d353bbb2b 291 Pfam PF00005 ABC transporter 19 158 1.4E-29 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR85_15455 dea5c3c79a84f3d647a4478d353bbb2b 291 Gene3D G3DSA:3.40.50.300 1 240 3.5E-52 T 31-10-2018 DFR85_15455 dea5c3c79a84f3d647a4478d353bbb2b 291 SMART SM00382 28 208 2.1E-13 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_14675 b24317b2bae0c52ac226acb5a4845fe9 204 Gene3D G3DSA:3.40.1050.10 4 183 5.6E-71 T 31-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 DFR85_14675 b24317b2bae0c52ac226acb5a4845fe9 204 Pfam PF00484 Carbonic anhydrase 32 179 5.3E-12 T 31-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DFR85_14675 b24317b2bae0c52ac226acb5a4845fe9 204 SMART SM00947 23 186 3.5E-11 T 31-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DFR85_14675 b24317b2bae0c52ac226acb5a4845fe9 204 SUPERFAMILY SSF53056 6 184 6.67E-32 T 31-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 DFR85_01590 d347c2f6f141fd62d73ad82da3837b1f 385 SUPERFAMILY SSF52540 21 264 2.92E-34 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_01590 d347c2f6f141fd62d73ad82da3837b1f 385 Gene3D G3DSA:1.10.8.60 206 285 2.6E-79 T 31-10-2018 DFR85_01590 d347c2f6f141fd62d73ad82da3837b1f 385 Hamap MF_01407 ORC1-type DNA replication protein. 6 373 24.38 T 31-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea DFR85_01590 d347c2f6f141fd62d73ad82da3837b1f 385 SUPERFAMILY SSF46785 282 377 1.77E-19 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_01590 d347c2f6f141fd62d73ad82da3837b1f 385 Pfam PF13401 AAA domain 59 177 8.6E-8 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_01590 d347c2f6f141fd62d73ad82da3837b1f 385 Gene3D G3DSA:3.40.50.300 38 205 2.6E-79 T 31-10-2018 DFR85_01590 d347c2f6f141fd62d73ad82da3837b1f 385 TIGRFAM TIGR02928 TIGR02928: orc1/cdc6 family replication initiation protein 25 359 2.4E-75 T 31-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea DFR85_01590 d347c2f6f141fd62d73ad82da3837b1f 385 SMART SM00382 52 206 0.0065 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_01590 d347c2f6f141fd62d73ad82da3837b1f 385 SMART SM01074 298 373 4.7E-17 T 31-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 DFR85_01590 d347c2f6f141fd62d73ad82da3837b1f 385 Gene3D G3DSA:1.10.10.10 292 384 7.3E-24 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_01590 d347c2f6f141fd62d73ad82da3837b1f 385 Pfam PF09079 CDC6, C terminal winged helix domain 310 370 1.2E-11 T 31-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 DFR85_02955 af6ebd401d0831da00d94ed98d93234f 351 Pfam PF14210 Domain of unknown function (DUF4322) 2 67 1.4E-40 T 31-10-2018 IPR025471 Domain of unknown function DUF4322 DFR85_02955 af6ebd401d0831da00d94ed98d93234f 351 Pfam PF01609 Transposase DDE domain 156 278 3.2E-6 T 31-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 DFR85_07715 a5261c03f6ded575d35764a89e5c10f7 61 SMART SM00746 7 45 2.2E-10 T 31-10-2018 IPR011017 TRASH domain DFR85_07715 a5261c03f6ded575d35764a89e5c10f7 61 Gene3D G3DSA:2.30.170.20 2 61 6.2E-25 T 31-10-2018 IPR038630 Ribosomal protein L24e/L24 superfamily DFR85_07715 a5261c03f6ded575d35764a89e5c10f7 61 Pfam PF01246 Ribosomal protein L24e 4 59 2.0E-19 T 31-10-2018 IPR000988 Ribosomal protein L24e-related DFR85_07715 a5261c03f6ded575d35764a89e5c10f7 61 SUPERFAMILY SSF57716 6 57 9.69E-15 T 31-10-2018 DFR85_07715 a5261c03f6ded575d35764a89e5c10f7 61 Hamap MF_00773 50S ribosomal protein L24e [rpl24e]. 2 56 26.51 T 31-10-2018 IPR023438 Ribosomal protein L24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_13555 771d5d0b0db6f0d14e84da370dd9e900 209 SUPERFAMILY SSF51556 1 198 8.04E-14 T 31-10-2018 IPR032466 Metal-dependent hydrolase DFR85_13555 771d5d0b0db6f0d14e84da370dd9e900 209 Pfam PF04909 Amidohydrolase 69 197 2.9E-8 T 31-10-2018 IPR006680 Amidohydrolase-related GO:0016787 DFR85_13555 771d5d0b0db6f0d14e84da370dd9e900 209 Gene3D G3DSA:3.20.20.140 47 208 1.6E-15 T 31-10-2018 DFR85_07295 1f48c05d524df1ee54845bfa94ab3c29 75 SUPERFAMILY SSF50182 6 73 1.54E-20 T 31-10-2018 IPR010920 LSM domain superfamily DFR85_07295 1f48c05d524df1ee54845bfa94ab3c29 75 Pfam PF01423 LSM domain 8 72 5.5E-24 T 31-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type DFR85_07295 1f48c05d524df1ee54845bfa94ab3c29 75 Gene3D G3DSA:2.30.30.100 1 75 1.0E-26 T 31-10-2018 DFR85_07295 1f48c05d524df1ee54845bfa94ab3c29 75 SMART SM00651 7 72 8.3E-27 T 31-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type DFR85_09840 3a02b738ff3e6617548097052c0d3e1b 312 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 16 265 1.8E-8 T 31-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD DFR85_11300 20e6db3f6aac5780fdef473ebf83fc9a 335 Gene3D G3DSA:3.30.470.20 1 196 5.0E-45 T 31-10-2018 DFR85_11300 20e6db3f6aac5780fdef473ebf83fc9a 335 PIRSF PIRSF001554 1 335 1.1E-95 T 31-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 DFR85_11300 20e6db3f6aac5780fdef473ebf83fc9a 335 Pfam PF00549 CoA-ligase 220 333 7.4E-16 T 31-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 DFR85_11300 20e6db3f6aac5780fdef473ebf83fc9a 335 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 213 237 - T 31-10-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 DFR85_11300 20e6db3f6aac5780fdef473ebf83fc9a 335 Gene3D G3DSA:3.40.50.261 206 335 4.7E-43 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 DFR85_11300 20e6db3f6aac5780fdef473ebf83fc9a 335 Gene3D G3DSA:3.30.1490.20 21 81 5.0E-45 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 DFR85_11300 20e6db3f6aac5780fdef473ebf83fc9a 335 SUPERFAMILY SSF56059 1 198 6.36E-41 T 31-10-2018 DFR85_11300 20e6db3f6aac5780fdef473ebf83fc9a 335 SUPERFAMILY SSF52210 207 333 4.58E-40 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 DFR85_11300 20e6db3f6aac5780fdef473ebf83fc9a 335 Pfam PF08442 ATP-grasp domain 2 169 3.3E-26 T 31-10-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 DFR85_03550 22cc6e39775eefc48edc4100a5d81486 238 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 13 228 1.0E-72 T 31-10-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 DFR85_03550 22cc6e39775eefc48edc4100a5d81486 238 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 148 159 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR85_03550 22cc6e39775eefc48edc4100a5d81486 238 Pfam PF13183 4Fe-4S dicluster domain 145 218 8.4E-12 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR85_03550 22cc6e39775eefc48edc4100a5d81486 238 SUPERFAMILY SSF54292 6 104 6.95E-23 T 31-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 DFR85_03550 22cc6e39775eefc48edc4100a5d81486 238 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 9 109 3.6E-33 T 31-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 DFR85_03550 22cc6e39775eefc48edc4100a5d81486 238 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 55 63 - T 31-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 DFR85_03550 22cc6e39775eefc48edc4100a5d81486 238 SUPERFAMILY SSF46548 105 230 9.24E-28 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 DFR85_03550 22cc6e39775eefc48edc4100a5d81486 238 Gene3D G3DSA:3.10.20.30 1 104 3.2E-32 T 31-10-2018 IPR012675 Beta-grasp domain superfamily DFR85_03550 22cc6e39775eefc48edc4100a5d81486 238 Gene3D G3DSA:1.10.1060.10 105 237 2.3E-40 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 DFR85_09305 20ca6556cecb955eaf854c3733893b41 209 Pfam PF04055 Radical SAM superfamily 27 184 2.1E-13 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR85_09305 20ca6556cecb955eaf854c3733893b41 209 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 3 209 35.257 T 31-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 DFR85_09305 20ca6556cecb955eaf854c3733893b41 209 PIRSF PIRSF000370 2 209 1.2E-50 T 31-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 DFR85_09305 20ca6556cecb955eaf854c3733893b41 209 Pfam PF13394 4Fe-4S single cluster domain 25 124 7.3E-15 T 31-10-2018 DFR85_09305 20ca6556cecb955eaf854c3733893b41 209 SUPERFAMILY SSF102114 26 202 1.83E-17 T 31-10-2018 DFR85_09305 20ca6556cecb955eaf854c3733893b41 209 Gene3D G3DSA:3.20.20.70 2 208 1.1E-42 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_09010 ed8fee0d2272012b3d1724eaa19e5773 317 Pfam PF00535 Glycosyl transferase family 2 3 121 9.5E-12 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 DFR85_09010 ed8fee0d2272012b3d1724eaa19e5773 317 Gene3D G3DSA:3.90.550.10 1 238 4.7E-18 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_09010 ed8fee0d2272012b3d1724eaa19e5773 317 SUPERFAMILY SSF53448 1 215 2.06E-23 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_13850 1df653d6a7ee44f9f3f8edb0b030dbec 603 Pfam PF13193 AMP-binding enzyme C-terminal domain 494 566 1.0E-17 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain DFR85_13850 1df653d6a7ee44f9f3f8edb0b030dbec 603 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 37 76 6.5E-9 T 31-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 DFR85_13850 1df653d6a7ee44f9f3f8edb0b030dbec 603 ProSitePatterns PS00455 Putative AMP-binding domain signature. 237 248 - T 31-10-2018 IPR020845 AMP-binding, conserved site DFR85_13850 1df653d6a7ee44f9f3f8edb0b030dbec 603 SUPERFAMILY SSF56801 35 600 1.83E-129 T 31-10-2018 DFR85_13850 1df653d6a7ee44f9f3f8edb0b030dbec 603 Gene3D G3DSA:3.30.300.30 481 602 8.0E-23 T 31-10-2018 DFR85_13850 1df653d6a7ee44f9f3f8edb0b030dbec 603 Gene3D G3DSA:3.40.50.12780 62 479 1.1E-82 T 31-10-2018 DFR85_13850 1df653d6a7ee44f9f3f8edb0b030dbec 603 Pfam PF00501 AMP-binding enzyme 90 486 1.1E-72 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 DFR85_06470 709c8881f01bbf4523e5164a3549bb93 393 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 81 229 4.7E-9 T 31-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like DFR85_08190 14221bf559d9970a162f1dad71b4b419 231 SUPERFAMILY SSF117396 2 230 9.94E-36 T 31-10-2018 IPR036520 UPF0759 superfamily DFR85_08190 14221bf559d9970a162f1dad71b4b419 231 Pfam PF01904 Protein of unknown function DUF72 12 229 1.5E-23 T 31-10-2018 IPR002763 Protein of unknown function DUF72 DFR85_08190 14221bf559d9970a162f1dad71b4b419 231 Gene3D G3DSA:3.20.20.410 1 231 1.5E-29 T 31-10-2018 IPR036520 UPF0759 superfamily DFR85_12785 368b0a5704133d8ed14e1e3617693cfc 160 SUPERFAMILY SSF56784 7 127 5.78E-9 T 31-10-2018 IPR036412 HAD-like superfamily DFR85_12785 368b0a5704133d8ed14e1e3617693cfc 160 Gene3D G3DSA:3.40.50.1000 34 157 4.0E-5 T 31-10-2018 IPR023214 HAD superfamily DFR85_07195 dfe297e04781d2ecc612ca8c515fa1b2 144 Hamap MF_00755 Ribonuclease P protein component 2 [rnp2]. 29 144 17.72 T 31-10-2018 IPR002759 Ribonuclease P/MRP protein subunit GO:0004540|GO:0008033 Reactome: R-HSA-6784531 DFR85_07195 dfe297e04781d2ecc612ca8c515fa1b2 144 SUPERFAMILY SSF160350 41 142 7.72E-22 T 31-10-2018 IPR038085 Rnp2-like domain superfamily Reactome: R-HSA-6784531 DFR85_07195 dfe297e04781d2ecc612ca8c515fa1b2 144 Gene3D G3DSA:3.30.70.3250 26 144 3.0E-23 T 31-10-2018 IPR038085 Rnp2-like domain superfamily Reactome: R-HSA-6784531 DFR85_07195 dfe297e04781d2ecc612ca8c515fa1b2 144 Pfam PF01900 Rpp14/Pop5 family 42 140 2.1E-14 T 31-10-2018 IPR002759 Ribonuclease P/MRP protein subunit GO:0004540|GO:0008033 Reactome: R-HSA-6784531 DFR85_02340 13b379144dd3246c3d2b49e4d857842f 437 Pfam PF14403 Circularly permuted ATP-grasp type 2 67 413 8.6E-77 T 31-10-2018 IPR025841 Circularly permuted ATP-grasp type 2 DFR85_02340 13b379144dd3246c3d2b49e4d857842f 437 Gene3D G3DSA:3.30.1490.270 322 375 5.1E-8 T 31-10-2018 DFR85_02340 13b379144dd3246c3d2b49e4d857842f 437 PIRSF PIRSF005522 16 437 2.3E-104 T 31-10-2018 IPR016450 Uncharacterised conserved protein UCP005522 DFR85_02340 13b379144dd3246c3d2b49e4d857842f 437 SUPERFAMILY SSF56059 43 430 3.54E-25 T 31-10-2018 DFR85_02340 13b379144dd3246c3d2b49e4d857842f 437 Gene3D G3DSA:3.40.50.11290 195 289 8.7E-21 T 31-10-2018 DFR85_08355 6617dcf9159bcd99cfa51ecac1d02080 330 Gene3D G3DSA:1.10.8.60 165 226 3.4E-19 T 31-10-2018 DFR85_08355 6617dcf9159bcd99cfa51ecac1d02080 330 Gene3D G3DSA:3.40.50.300 2 163 5.0E-53 T 31-10-2018 DFR85_08355 6617dcf9159bcd99cfa51ecac1d02080 330 SUPERFAMILY SSF52540 8 215 1.99E-50 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_08355 6617dcf9159bcd99cfa51ecac1d02080 330 Pfam PF08542 Replication factor C C-terminal domain 229 316 2.0E-24 T 31-10-2018 IPR013748 Replication factor C, C-terminal Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-176187|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804756|Reactome: R-HSA-69091|Reactome: R-HSA-69473 DFR85_08355 6617dcf9159bcd99cfa51ecac1d02080 330 SUPERFAMILY SSF48019 229 320 3.91E-23 T 31-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 DFR85_08355 6617dcf9159bcd99cfa51ecac1d02080 330 Hamap MF_01509 Replication factor C small subunit [rfcS]. 6 321 49.176 T 31-10-2018 IPR023748 Replication factor C small subunit, archaeal GO:0003689|GO:0005524|GO:0005663|GO:0006260 DFR85_08355 6617dcf9159bcd99cfa51ecac1d02080 330 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 44 157 2.3E-14 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 DFR85_08355 6617dcf9159bcd99cfa51ecac1d02080 330 SMART SM00382 40 167 1.7E-13 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_08355 6617dcf9159bcd99cfa51ecac1d02080 330 Gene3D G3DSA:1.20.272.10 228 323 3.2E-34 T 31-10-2018 DFR85_04260 cccd3eb7c75c709705b0f87c5ec041c5 322 Gene3D G3DSA:3.90.550.10 1 245 4.4E-26 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_04260 cccd3eb7c75c709705b0f87c5ec041c5 322 Pfam PF00535 Glycosyl transferase family 2 4 153 1.4E-16 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 DFR85_04260 cccd3eb7c75c709705b0f87c5ec041c5 322 SUPERFAMILY SSF53448 2 281 7.16E-25 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_05435 133335d4aace87e243a00cdd852dfd85 82 Gene3D G3DSA:3.30.390.50 5 80 5.2E-9 T 31-10-2018 DFR85_05435 133335d4aace87e243a00cdd852dfd85 82 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 29 66 1.1E-5 T 31-10-2018 IPR019491 Lipoate protein ligase, C-terminal KEGG: 00785+6.3.1.20 DFR85_05435 133335d4aace87e243a00cdd852dfd85 82 SUPERFAMILY SSF82649 30 77 3.4E-5 T 31-10-2018 DFR85_12025 c3cc94c916c3be0be3b637e4895590ab 290 Pfam PF02754 Cysteine-rich domain 190 274 8.9E-6 T 31-10-2018 IPR004017 Cysteine-rich domain DFR85_09930 b6ee35c4adc561613434a25c914012e0 238 Gene3D G3DSA:1.10.260.40 17 76 1.7E-9 T 31-10-2018 DFR85_09930 b6ee35c4adc561613434a25c914012e0 238 Pfam PF01381 Helix-turn-helix 29 70 2.3E-9 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DFR85_09930 b6ee35c4adc561613434a25c914012e0 238 PIRSF PIRSF037724 1 234 3.1E-77 T 31-10-2018 IPR017271 Transcription regulator HTH, MJ1545, predicted DFR85_09930 b6ee35c4adc561613434a25c914012e0 238 SUPERFAMILY SSF47413 22 73 1.34E-10 T 31-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 DFR85_09930 b6ee35c4adc561613434a25c914012e0 238 SMART SM00530 27 81 2.1E-9 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DFR85_06875 6ad34ee2613efc894c22dbfc57c08a56 252 Gene3D G3DSA:3.40.50.720 1 249 1.3E-77 T 31-10-2018 DFR85_06875 6ad34ee2613efc894c22dbfc57c08a56 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 4.2E-11 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_06875 6ad34ee2613efc894c22dbfc57c08a56 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 4.2E-11 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_06875 6ad34ee2613efc894c22dbfc57c08a56 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 4.2E-11 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_06875 6ad34ee2613efc894c22dbfc57c08a56 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 243 2.9E-62 T 31-10-2018 DFR85_06875 6ad34ee2613efc894c22dbfc57c08a56 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 4.7E-42 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_06875 6ad34ee2613efc894c22dbfc57c08a56 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 4.7E-42 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_06875 6ad34ee2613efc894c22dbfc57c08a56 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 4.7E-42 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_06875 6ad34ee2613efc894c22dbfc57c08a56 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 4.7E-42 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_06875 6ad34ee2613efc894c22dbfc57c08a56 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 4.7E-42 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_06875 6ad34ee2613efc894c22dbfc57c08a56 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 4.7E-42 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_06875 6ad34ee2613efc894c22dbfc57c08a56 252 SUPERFAMILY SSF51735 4 244 1.07E-78 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_07990 b1321b0f454f4d056d2322ff57f5167c 48 Gene3D G3DSA:1.10.1220.10 8 45 1.1E-9 T 31-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 DFR85_07990 b1321b0f454f4d056d2322ff57f5167c 48 Pfam PF01402 Ribbon-helix-helix protein, copG family 4 40 6.2E-9 T 31-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 DFR85_07990 b1321b0f454f4d056d2322ff57f5167c 48 SUPERFAMILY SSF47598 1 46 1.33E-12 T 31-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 DFR85_13685 fcb730b7ef5f015a93d420371984677a 454 Gene3D G3DSA:1.20.210.10 3 452 6.7E-38 T 31-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_13685 fcb730b7ef5f015a93d420371984677a 454 SUPERFAMILY SSF81442 7 435 5.89E-34 T 31-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_13685 fcb730b7ef5f015a93d420371984677a 454 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 7 414 4.1E-33 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_13315 7ebd4fb4024e1f9e6f79291e4eb51816 931 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 526 532 - T 31-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 DFR85_13315 7ebd4fb4024e1f9e6f79291e4eb51816 931 Pfam PF06634 Protein of unknown function (DUF1156) 21 63 9.6E-8 T 31-10-2018 IPR009537 Domain of unknown function DUF1156 DFR85_13315 7ebd4fb4024e1f9e6f79291e4eb51816 931 SUPERFAMILY SSF53335 96 628 4.22E-10 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR85_13315 7ebd4fb4024e1f9e6f79291e4eb51816 931 SUPERFAMILY SSF53335 404 538 1.2E-5 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR85_08275 8ff0b3e26a4e26d1df539305d9c187f5 89 Gene3D G3DSA:1.20.1440.50 6 89 2.2E-33 T 31-10-2018 IPR023130 Ta0600-like superfamily DFR85_08275 8ff0b3e26a4e26d1df539305d9c187f5 89 ProDom PD029943 UPF0147 ARCHAEAL PF0239 ST0460.1 MM1385 CYTOSOLIC SACI_0891 TV0625 APES069 TA0600 11 88 3.0E-35 T 31-10-2018 IPR005354 Uncharacterised protein family UPF0147 DFR85_08275 8ff0b3e26a4e26d1df539305d9c187f5 89 SUPERFAMILY SSF158436 4 89 1.57E-34 T 31-10-2018 DFR85_08275 8ff0b3e26a4e26d1df539305d9c187f5 89 Hamap MF_00342 UPF0147 protein . 7 88 31.269 T 31-10-2018 IPR005354 Uncharacterised protein family UPF0147 DFR85_08275 8ff0b3e26a4e26d1df539305d9c187f5 89 Pfam PF03685 Uncharacterised protein family (UPF0147) 7 87 1.9E-36 T 31-10-2018 IPR005354 Uncharacterised protein family UPF0147 DFR85_14755 6964487b5a3cf3145e6bfdb2f6bdf0f3 136 Gene3D G3DSA:3.10.129.10 1 128 1.3E-30 T 31-10-2018 DFR85_14755 6964487b5a3cf3145e6bfdb2f6bdf0f3 136 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 14 125 6.7E-18 T 31-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 DFR85_14755 6964487b5a3cf3145e6bfdb2f6bdf0f3 136 SUPERFAMILY SSF54637 6 131 3.36E-27 T 31-10-2018 IPR029069 HotDog domain superfamily DFR85_14755 6964487b5a3cf3145e6bfdb2f6bdf0f3 136 Pfam PF03061 Thioesterase superfamily 43 117 1.7E-15 T 31-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 DFR85_12205 bb13cc8a8b015850fbf2aeb18afccd2f 139 SUPERFAMILY SSF102114 3 75 5.89E-8 T 31-10-2018 DFR85_12205 bb13cc8a8b015850fbf2aeb18afccd2f 139 Gene3D G3DSA:3.20.20.70 2 118 1.6E-12 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_12205 bb13cc8a8b015850fbf2aeb18afccd2f 139 Pfam PF13186 Iron-sulfur cluster-binding domain 5 69 3.7E-7 T 31-10-2018 IPR023885 4Fe4S-binding SPASM domain DFR85_12205 bb13cc8a8b015850fbf2aeb18afccd2f 139 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 5 77 1.6E-12 T 31-10-2018 IPR023885 4Fe4S-binding SPASM domain DFR85_14250 bee5cabce320f9beeaae5bea4ab33de9 436 SUPERFAMILY SSF50800 67 140 6.45E-7 T 31-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily DFR85_14250 bee5cabce320f9beeaae5bea4ab33de9 436 SUPERFAMILY SSF52935 295 425 2.75E-20 T 31-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR85_14250 bee5cabce320f9beeaae5bea4ab33de9 436 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 6 431 4.3E-92 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR85_14250 bee5cabce320f9beeaae5bea4ab33de9 436 Gene3D G3DSA:3.40.1380.20 314 435 1.1E-18 T 31-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR85_14250 bee5cabce320f9beeaae5bea4ab33de9 436 PRINTS PR01050 Pyruvate kinase family signature 241 265 5.3E-45 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR85_14250 bee5cabce320f9beeaae5bea4ab33de9 436 PRINTS PR01050 Pyruvate kinase family signature 51 67 5.3E-45 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR85_14250 bee5cabce320f9beeaae5bea4ab33de9 436 PRINTS PR01050 Pyruvate kinase family signature 266 284 5.3E-45 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR85_14250 bee5cabce320f9beeaae5bea4ab33de9 436 PRINTS PR01050 Pyruvate kinase family signature 162 176 5.3E-45 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR85_14250 bee5cabce320f9beeaae5bea4ab33de9 436 PRINTS PR01050 Pyruvate kinase family signature 216 240 5.3E-45 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR85_14250 bee5cabce320f9beeaae5bea4ab33de9 436 PRINTS PR01050 Pyruvate kinase family signature 189 215 5.3E-45 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR85_14250 bee5cabce320f9beeaae5bea4ab33de9 436 PRINTS PR01050 Pyruvate kinase family signature 285 301 5.3E-45 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR85_14250 bee5cabce320f9beeaae5bea4ab33de9 436 SUPERFAMILY SSF51621 4 311 5.23E-59 T 31-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 DFR85_14250 bee5cabce320f9beeaae5bea4ab33de9 436 Gene3D G3DSA:3.20.20.60 9 301 7.1E-76 T 31-10-2018 DFR85_14250 bee5cabce320f9beeaae5bea4ab33de9 436 Pfam PF00224 Pyruvate kinase, barrel domain 6 311 7.3E-58 T 31-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR85_14250 bee5cabce320f9beeaae5bea4ab33de9 436 Pfam PF02887 Pyruvate kinase, alpha/beta domain 326 424 2.5E-14 T 31-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR85_14250 bee5cabce320f9beeaae5bea4ab33de9 436 Gene3D G3DSA:2.40.33.10 62 144 7.1E-76 T 31-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 DFR85_03030 7bb914b9590743ce92d7c00b921387ef 342 Pfam PF03595 Voltage-dependent anion channel 8 332 1.4E-35 T 31-10-2018 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 DFR85_03030 7bb914b9590743ce92d7c00b921387ef 342 Gene3D G3DSA:1.50.10.150 3 339 3.3E-9 T 31-10-2018 IPR038665 Voltage-dependent anion channel superfamily DFR85_11220 5da868a87f4cbc85ab16bdcbcc6b7117 422 Gene3D G3DSA:1.10.1410.30 13 259 1.7E-89 T 31-10-2018 DFR85_11220 5da868a87f4cbc85ab16bdcbcc6b7117 422 Pfam PF09249 tRNA nucleotidyltransferase, second domain 151 260 2.7E-43 T 31-10-2018 IPR015329 tRNA nucleotidyltransferase, substrate binding GO:0004810|GO:0016437 DFR85_11220 5da868a87f4cbc85ab16bdcbcc6b7117 422 Pfam PF01909 Nucleotidyltransferase domain 33 136 2.6E-14 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 DFR85_11220 5da868a87f4cbc85ab16bdcbcc6b7117 422 SUPERFAMILY SSF55003 246 420 4.32E-36 T 31-10-2018 IPR011068 Nucleotidyltransferase, class I-like, C-terminal GO:0003723|GO:0016779|GO:0031123 DFR85_11220 5da868a87f4cbc85ab16bdcbcc6b7117 422 PIRSF PIRSF005335 5 421 1.2E-131 T 31-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 DFR85_11220 5da868a87f4cbc85ab16bdcbcc6b7117 422 SUPERFAMILY SSF81301 8 145 2.02E-33 T 31-10-2018 DFR85_11220 5da868a87f4cbc85ab16bdcbcc6b7117 422 Hamap MF_01264 CCA-adding enzyme [cca]. 1 422 136.42 T 31-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 DFR85_11220 5da868a87f4cbc85ab16bdcbcc6b7117 422 SUPERFAMILY SSF81631 149 261 6.83E-38 T 31-10-2018 DFR85_11220 5da868a87f4cbc85ab16bdcbcc6b7117 422 TIGRFAM TIGR03671 cca_archaeal: CCA-adding enzyme 11 389 1.2E-129 T 31-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 DFR85_11220 5da868a87f4cbc85ab16bdcbcc6b7117 422 Gene3D G3DSA:3.30.460.10 20 147 1.7E-89 T 31-10-2018 DFR85_04095 c61823c263e25d1060fe81496080e297 439 Pfam PF05691 Raffinose synthase or seed imbibition protein Sip1 133 320 2.4E-21 T 31-10-2018 IPR008811 Glycosyl hydrolases 36 DFR85_04095 c61823c263e25d1060fe81496080e297 439 Pfam PF05691 Raffinose synthase or seed imbibition protein Sip1 3 70 6.8E-13 T 31-10-2018 IPR008811 Glycosyl hydrolases 36 DFR85_04095 c61823c263e25d1060fe81496080e297 439 Gene3D G3DSA:3.20.20.70 17 288 1.0E-14 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_04095 c61823c263e25d1060fe81496080e297 439 SUPERFAMILY SSF51445 12 277 5.0E-41 T 31-10-2018 IPR017853 Glycoside hydrolase superfamily DFR85_10845 848d58410e6ab68c755adfc62f8762e9 105 Pfam PF03091 CutA1 divalent ion tolerance protein 5 101 1.3E-35 T 31-10-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 DFR85_10845 848d58410e6ab68c755adfc62f8762e9 105 Gene3D G3DSA:3.30.70.120 1 104 2.5E-39 T 31-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal DFR85_10845 848d58410e6ab68c755adfc62f8762e9 105 SUPERFAMILY SSF54913 3 104 2.48E-37 T 31-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta DFR85_01020 f2c47b6189dc208ffadd94309d5977c1 307 PIRSF PIRSF004944 1 307 1.2E-114 T 31-10-2018 IPR014426 Uncharacterised protein family UPF0282, hydrolase, metallo-beta-lactamase DFR85_01020 f2c47b6189dc208ffadd94309d5977c1 307 Hamap MF_01406 UPF0282 protein . 1 287 38.99 T 31-10-2018 IPR014426 Uncharacterised protein family UPF0282, hydrolase, metallo-beta-lactamase DFR85_01020 f2c47b6189dc208ffadd94309d5977c1 307 SUPERFAMILY SSF56281 15 264 8.78E-17 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR85_01020 f2c47b6189dc208ffadd94309d5977c1 307 Gene3D G3DSA:3.60.15.10 9 272 9.3E-13 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR85_01020 f2c47b6189dc208ffadd94309d5977c1 307 Pfam PF13483 Beta-lactamase superfamily domain 17 162 1.0E-4 T 31-10-2018 DFR85_07875 75453a2f8b6a7b5a8292f438372daee9 154 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 4 95 2.1E-11 T 31-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 DFR85_07875 75453a2f8b6a7b5a8292f438372daee9 154 PIRSF PIRSF015750 1 154 7.8E-71 T 31-10-2018 IPR006399 Riboflavin synthase, archaeal GO:0004746|GO:0009231 KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 DFR85_07875 75453a2f8b6a7b5a8292f438372daee9 154 Gene3D G3DSA:3.40.50.960 1 154 5.8E-50 T 31-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 DFR85_07875 75453a2f8b6a7b5a8292f438372daee9 154 TIGRFAM TIGR01506 ribC_arch: riboflavin synthase 4 153 7.7E-63 T 31-10-2018 IPR006399 Riboflavin synthase, archaeal GO:0004746|GO:0009231 KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 DFR85_07875 75453a2f8b6a7b5a8292f438372daee9 154 SUPERFAMILY SSF52121 3 129 2.62E-25 T 31-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 DFR85_05665 f1c26cd9dc47da9eef7a6b92b47afbc0 248 SUPERFAMILY SSF51735 115 240 1.08E-11 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_05665 f1c26cd9dc47da9eef7a6b92b47afbc0 248 SUPERFAMILY SSF81324 8 136 5.1E-21 T 31-10-2018 DFR85_05665 f1c26cd9dc47da9eef7a6b92b47afbc0 248 Pfam PF02254 TrkA-N domain 117 223 1.3E-11 T 31-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 DFR85_05665 f1c26cd9dc47da9eef7a6b92b47afbc0 248 Gene3D G3DSA:1.10.287.70 3 98 3.6E-18 T 31-10-2018 DFR85_05665 f1c26cd9dc47da9eef7a6b92b47afbc0 248 Gene3D G3DSA:3.40.50.720 110 246 4.1E-14 T 31-10-2018 DFR85_05665 f1c26cd9dc47da9eef7a6b92b47afbc0 248 Pfam PF07885 Ion channel 14 91 1.6E-16 T 31-10-2018 IPR013099 Potassium channel domain DFR85_07425 6a44ce573439b0c267e9e1dff804567c 553 ProSitePatterns PS00750 Chaperonins TCP-1 signature 1. 47 59 - T 31-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR85_07425 6a44ce573439b0c267e9e1dff804567c 553 ProSitePatterns PS00751 Chaperonins TCP-1 signature 2. 68 84 - T 31-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR85_07425 6a44ce573439b0c267e9e1dff804567c 553 SUPERFAMILY SSF48592 24 531 2.52E-85 T 31-10-2018 IPR027413 GroEL-like equatorial domain superfamily DFR85_07425 6a44ce573439b0c267e9e1dff804567c 553 Gene3D G3DSA:1.10.560.10 35 529 1.5E-211 T 31-10-2018 IPR027413 GroEL-like equatorial domain superfamily DFR85_07425 6a44ce573439b0c267e9e1dff804567c 553 Gene3D G3DSA:3.50.7.10 224 375 1.5E-211 T 31-10-2018 IPR027409 GroEL-like apical domain superfamily DFR85_07425 6a44ce573439b0c267e9e1dff804567c 553 Pfam PF00118 TCP-1/cpn60 chaperonin family 43 533 2.9E-173 T 31-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 DFR85_07425 6a44ce573439b0c267e9e1dff804567c 553 SUPERFAMILY SSF54849 155 412 6.1E-28 T 31-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily DFR85_07425 6a44ce573439b0c267e9e1dff804567c 553 ProSitePatterns PS00995 Chaperonins TCP-1 signature 3. 96 104 - T 31-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR85_07425 6a44ce573439b0c267e9e1dff804567c 553 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 380 402 1.6E-27 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR85_07425 6a44ce573439b0c267e9e1dff804567c 553 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 414 426 1.6E-27 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR85_07425 6a44ce573439b0c267e9e1dff804567c 553 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 96 115 1.6E-27 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR85_07425 6a44ce573439b0c267e9e1dff804567c 553 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 44 60 1.6E-27 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR85_07425 6a44ce573439b0c267e9e1dff804567c 553 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 66 84 1.6E-27 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 DFR85_07425 6a44ce573439b0c267e9e1dff804567c 553 Gene3D G3DSA:3.30.260.10 153 411 1.5E-211 T 31-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily DFR85_07425 6a44ce573439b0c267e9e1dff804567c 553 TIGRFAM TIGR02339 thermosome_arch: thermosome, various subunits, archaeal 15 532 5.2E-242 T 31-10-2018 IPR012714 Thermosome, archaeal GO:0005524|GO:0006457|GO:0051082 DFR85_07425 6a44ce573439b0c267e9e1dff804567c 553 SUPERFAMILY SSF52029 219 385 1.12E-58 T 31-10-2018 IPR027409 GroEL-like apical domain superfamily DFR85_07315 027b458aa6e86892ca45e5631045bd02 352 Hamap MF_00497_A Glycerol-1-phosphate dehydrogenase [NAD(P)+] [egsA]. 7 351 44.826 T 31-10-2018 IPR023002 Glycerol-1-phosphate dehydrogenase, archaea GO:0050492|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 DFR85_07315 027b458aa6e86892ca45e5631045bd02 352 Pfam PF13685 Iron-containing alcohol dehydrogenase 16 273 3.6E-68 T 31-10-2018 IPR032837 Glycerol-1-phosphate dehydrogenase KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 DFR85_07315 027b458aa6e86892ca45e5631045bd02 352 Gene3D G3DSA:3.40.50.1970 1 159 3.0E-33 T 31-10-2018 DFR85_07315 027b458aa6e86892ca45e5631045bd02 352 Gene3D G3DSA:1.20.1090.10 161 351 1.2E-59 T 31-10-2018 DFR85_07315 027b458aa6e86892ca45e5631045bd02 352 SUPERFAMILY SSF56796 5 337 3.01E-70 T 31-10-2018 DFR85_07315 027b458aa6e86892ca45e5631045bd02 352 PIRSF PIRSF000112 1 348 4.1E-65 T 31-10-2018 IPR016205 Glycerol dehydrogenase GO:0016614|GO:0046872|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 DFR85_08880 03eb404838edf07f960eeb2a6f38ee69 184 Gene3D G3DSA:3.10.290.10 103 179 5.6E-15 T 31-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 DFR85_08880 03eb404838edf07f960eeb2a6f38ee69 184 TIGRFAM TIGR01018 uS4_arch: ribosomal protein uS4 1 162 2.4E-65 T 31-10-2018 IPR005710 Ribosomal protein S4/S9, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_08880 03eb404838edf07f960eeb2a6f38ee69 184 SUPERFAMILY SSF55174 9 161 2.36E-28 T 31-10-2018 DFR85_08880 03eb404838edf07f960eeb2a6f38ee69 184 Hamap MF_01306_A 30S ribosomal protein S4 [rpsD]. 1 157 31.656 T 31-10-2018 IPR022802 Ribosomal protein S4, archaeal GO:0006412|GO:0019843 DFR85_08880 03eb404838edf07f960eeb2a6f38ee69 184 ProSitePatterns PS00632 Ribosomal protein S4 signature. 102 126 - T 31-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_08880 03eb404838edf07f960eeb2a6f38ee69 184 SMART SM00363 104 166 3.1E-11 T 31-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_08880 03eb404838edf07f960eeb2a6f38ee69 184 SMART SM01390 4 103 1.6E-15 T 31-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 DFR85_08880 03eb404838edf07f960eeb2a6f38ee69 184 Pfam PF01479 S4 domain 104 149 4.0E-14 T 31-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_10565 4a961911882c9e35bf6362a9ccf728f1 419 Pfam PF04715 Anthranilate synthase component I, N terminal region 11 131 5.0E-18 T 31-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 DFR85_10565 4a961911882c9e35bf6362a9ccf728f1 419 PRINTS PR00095 Anthranilate synthase component I signature 272 285 7.4E-16 T 31-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 DFR85_10565 4a961911882c9e35bf6362a9ccf728f1 419 PRINTS PR00095 Anthranilate synthase component I signature 258 271 7.4E-16 T 31-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 DFR85_10565 4a961911882c9e35bf6362a9ccf728f1 419 PRINTS PR00095 Anthranilate synthase component I signature 352 366 7.4E-16 T 31-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 DFR85_10565 4a961911882c9e35bf6362a9ccf728f1 419 PRINTS PR00095 Anthranilate synthase component I signature 366 380 7.4E-16 T 31-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 DFR85_10565 4a961911882c9e35bf6362a9ccf728f1 419 SUPERFAMILY SSF56322 9 418 5.36E-138 T 31-10-2018 IPR005801 ADC synthase GO:0009058 DFR85_10565 4a961911882c9e35bf6362a9ccf728f1 419 Gene3D G3DSA:3.60.120.10 1 419 2.4E-154 T 31-10-2018 IPR005801 ADC synthase GO:0009058 DFR85_10565 4a961911882c9e35bf6362a9ccf728f1 419 Pfam PF00425 chorismate binding enzyme 157 409 2.6E-93 T 31-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal DFR85_14195 c0ebde4a9e76a6e2a9a53eb8b5d6bbe6 116 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 27 92 2.1E-9 T 31-10-2018 IPR002831 Transcription regulator TrmB, N-terminal DFR85_14195 c0ebde4a9e76a6e2a9a53eb8b5d6bbe6 116 SUPERFAMILY SSF46785 23 102 1.05E-13 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_14195 c0ebde4a9e76a6e2a9a53eb8b5d6bbe6 116 Gene3D G3DSA:1.10.10.10 15 116 9.0E-21 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_09445 56406b0ee2fa75c159db8bc566c5362d 193 Gene3D G3DSA:3.30.230.40 91 193 7.0E-34 T 31-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 DFR85_09445 56406b0ee2fa75c159db8bc566c5362d 193 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 32 175 6.1E-50 T 31-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 DFR85_09445 56406b0ee2fa75c159db8bc566c5362d 193 Gene3D G3DSA:3.30.230.40 1 90 1.3E-26 T 31-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 DFR85_09445 56406b0ee2fa75c159db8bc566c5362d 193 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 157 169 - T 31-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 DFR85_09445 56406b0ee2fa75c159db8bc566c5362d 193 SUPERFAMILY SSF54211 3 86 2.66E-24 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold DFR85_09445 56406b0ee2fa75c159db8bc566c5362d 193 SUPERFAMILY SSF54211 88 180 1.39E-30 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold DFR85_09445 56406b0ee2fa75c159db8bc566c5362d 193 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 3 193 34.745 T 31-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 DFR85_09445 56406b0ee2fa75c159db8bc566c5362d 193 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 62 75 - T 31-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 DFR85_12010 a9fbd841b5c9bfe59c7ea8e85d1399b7 512 SUPERFAMILY SSF53649 155 362 1.11E-6 T 31-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 DFR85_12010 a9fbd841b5c9bfe59c7ea8e85d1399b7 512 Pfam PF04185 Phosphoesterase family 30 368 2.2E-71 T 31-10-2018 IPR007312 Phosphoesterase GO:0016788 DFR85_12010 a9fbd841b5c9bfe59c7ea8e85d1399b7 512 Gene3D G3DSA:3.40.720.10 260 411 8.3E-35 T 31-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 DFR85_12010 a9fbd841b5c9bfe59c7ea8e85d1399b7 512 Gene3D G3DSA:3.40.720.10 21 185 1.1E-21 T 31-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 DFR85_13950 ccf3c7509577a40712496e749ca015af 479 Pfam PF05317 Thermopsin 129 389 1.0E-74 T 31-10-2018 IPR007981 Peptidase A5, thermopsin DFR85_06105 c53d543dc1fa6d379444c975acf21829 385 SUPERFAMILY SSF52540 10 195 3.92E-24 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_06105 c53d543dc1fa6d379444c975acf21829 385 Gene3D G3DSA:3.40.50.300 8 204 3.0E-45 T 31-10-2018 DFR85_06105 c53d543dc1fa6d379444c975acf21829 385 Pfam PF07728 AAA domain (dynein-related subfamily) 43 170 2.4E-27 T 31-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 DFR85_06105 c53d543dc1fa6d379444c975acf21829 385 SMART SM00382 40 180 7.1E-4 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_09810 a02705c69b6ac1087c3bfa72a56ae6bf 346 SUPERFAMILY SSF56796 19 338 7.98E-87 T 31-10-2018 DFR85_09810 a02705c69b6ac1087c3bfa72a56ae6bf 346 Gene3D G3DSA:3.40.50.1970 5 155 1.2E-46 T 31-10-2018 DFR85_09810 a02705c69b6ac1087c3bfa72a56ae6bf 346 Pfam PF01761 3-dehydroquinate synthase 50 311 1.3E-92 T 31-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 DFR85_09810 a02705c69b6ac1087c3bfa72a56ae6bf 346 PIRSF PIRSF001455 15 345 4.9E-113 T 31-10-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 DFR85_09810 a02705c69b6ac1087c3bfa72a56ae6bf 346 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 1 346 56.076 T 31-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 DFR85_09810 a02705c69b6ac1087c3bfa72a56ae6bf 346 Gene3D G3DSA:1.20.1090.10 156 344 1.4E-50 T 31-10-2018 DFR85_09810 a02705c69b6ac1087c3bfa72a56ae6bf 346 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 45 337 3.2E-106 T 31-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 DFR85_01365 126259996d518fb022031ea5d87b8e75 305 Pfam PF01545 Cation efflux family 17 195 1.2E-16 T 31-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 DFR85_01365 126259996d518fb022031ea5d87b8e75 305 Gene3D G3DSA:1.20.1510.10 10 195 1.7E-6 T 31-10-2018 IPR027469 Cation efflux transmembrane domain superfamily DFR85_01365 126259996d518fb022031ea5d87b8e75 305 SUPERFAMILY SSF161111 8 196 1.01E-12 T 31-10-2018 IPR027469 Cation efflux transmembrane domain superfamily DFR85_06725 a3851250e2ad0ab0d695393b31bf8508 292 PRINTS PR00151 Porphobilinogen deaminase signature 135 152 2.3E-23 T 31-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 DFR85_06725 a3851250e2ad0ab0d695393b31bf8508 292 PRINTS PR00151 Porphobilinogen deaminase signature 220 237 2.3E-23 T 31-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 DFR85_06725 a3851250e2ad0ab0d695393b31bf8508 292 PRINTS PR00151 Porphobilinogen deaminase signature 116 133 2.3E-23 T 31-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 DFR85_06725 a3851250e2ad0ab0d695393b31bf8508 292 PRINTS PR00151 Porphobilinogen deaminase signature 70 89 2.3E-23 T 31-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 DFR85_06725 a3851250e2ad0ab0d695393b31bf8508 292 SUPERFAMILY SSF54782 210 288 8.24E-12 T 31-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 DFR85_06725 a3851250e2ad0ab0d695393b31bf8508 292 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 221 237 - T 31-10-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 DFR85_06725 a3851250e2ad0ab0d695393b31bf8508 292 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 217 282 4.2E-7 T 31-10-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 DFR85_06725 a3851250e2ad0ab0d695393b31bf8508 292 SUPERFAMILY SSF53850 1 204 2.34E-56 T 31-10-2018 DFR85_06725 a3851250e2ad0ab0d695393b31bf8508 292 Gene3D G3DSA:3.30.160.40 211 290 8.5E-8 T 31-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 DFR85_06725 a3851250e2ad0ab0d695393b31bf8508 292 Gene3D G3DSA:3.40.190.10 94 190 2.3E-55 T 31-10-2018 DFR85_06725 a3851250e2ad0ab0d695393b31bf8508 292 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 3 284 1.6E-82 T 31-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 DFR85_06725 a3851250e2ad0ab0d695393b31bf8508 292 Gene3D G3DSA:3.40.190.10 3 203 2.3E-55 T 31-10-2018 DFR85_06725 a3851250e2ad0ab0d695393b31bf8508 292 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 3 203 5.1E-56 T 31-10-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 DFR85_06725 a3851250e2ad0ab0d695393b31bf8508 292 PIRSF PIRSF001438 1 292 4.0E-80 T 31-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 DFR85_00140 7775931a608b216576cfd89727866fdc 281 SUPERFAMILY SSF103473 10 265 2.49E-43 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_00140 7775931a608b216576cfd89727866fdc 281 ProSitePatterns PS00217 Sugar transport proteins signature 2. 116 141 - T 31-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DFR85_00140 7775931a608b216576cfd89727866fdc 281 Pfam PF00083 Sugar (and other) transporter 23 272 3.5E-50 T 31-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 DFR85_00140 7775931a608b216576cfd89727866fdc 281 Gene3D G3DSA:1.20.1250.20 13 276 1.8E-62 T 31-10-2018 DFR85_00140 7775931a608b216576cfd89727866fdc 281 PRINTS PR00171 Sugar transporter signature 30 40 6.9E-7 T 31-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 DFR85_00140 7775931a608b216576cfd89727866fdc 281 PRINTS PR00171 Sugar transporter signature 111 130 6.9E-7 T 31-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 DFR85_00140 7775931a608b216576cfd89727866fdc 281 PRINTS PR00171 Sugar transporter signature 265 275 6.9E-7 T 31-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 DFR85_05750 b67b31c9a8168b7c37dee48ca64b405c 225 Gene3D G3DSA:3.40.50.1860 1 93 1.4E-42 T 31-10-2018 DFR85_05750 b67b31c9a8168b7c37dee48ca64b405c 225 Gene3D G3DSA:3.40.50.11330 94 223 5.4E-41 T 31-10-2018 DFR85_11805 1db863f6a6a1a71149f9d02e39e44ff8 228 Pfam PF12916 Protein of unknown function (DUF3834) 1 201 8.1E-53 T 31-10-2018 IPR024533 Protein of unknown function DUF3834 DFR85_11805 1db863f6a6a1a71149f9d02e39e44ff8 228 Gene3D G3DSA:3.40.190.200 1 228 4.7E-77 T 31-10-2018 DFR85_02540 a26ac4787f7b961596d6ab9d3b9b29e7 438 SUPERFAMILY SSF53383 9 422 2.33E-88 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase DFR85_02540 a26ac4787f7b961596d6ab9d3b9b29e7 438 Gene3D G3DSA:3.40.640.10 74 317 8.0E-134 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR85_02540 a26ac4787f7b961596d6ab9d3b9b29e7 438 Pfam PF00202 Aminotransferase class-III 37 372 6.3E-59 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DFR85_02540 a26ac4787f7b961596d6ab9d3b9b29e7 438 Gene3D G3DSA:3.90.1150.10 16 416 8.0E-134 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 DFR85_07735 49c3d44a9483a27c116d7b39b2564644 83 Pfam PF01191 RNA polymerase Rpb5, C-terminal domain 12 80 7.4E-30 T 31-10-2018 IPR000783 RNA polymerase, subunit H/Rpb5 C-terminal GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 DFR85_07735 49c3d44a9483a27c116d7b39b2564644 83 SUPERFAMILY SSF55287 9 81 8.89E-26 T 31-10-2018 IPR035913 RPB5-like RNA polymerase subunit superfamily Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 DFR85_07735 49c3d44a9483a27c116d7b39b2564644 83 Hamap MF_00025 DNA-directed RNA polymerase subunit H [rpoH]. 8 81 22.605 T 31-10-2018 IPR020609 Archaeal RpoH /eukaryotic RPB5 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 DFR85_07735 49c3d44a9483a27c116d7b39b2564644 83 Gene3D G3DSA:3.90.940.20 1 83 4.8E-34 T 31-10-2018 IPR035913 RPB5-like RNA polymerase subunit superfamily Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 DFR85_07735 49c3d44a9483a27c116d7b39b2564644 83 ProDom PD005155 RNA POLYMERASE DNA-DIRECTED SUBUNIT NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION II H POLYPEPTIDE 14 81 5.0E-25 T 31-10-2018 IPR000783 RNA polymerase, subunit H/Rpb5 C-terminal GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 DFR85_07735 49c3d44a9483a27c116d7b39b2564644 83 ProSitePatterns PS01110 RNA polymerases H / 23 Kd subunits signature. 13 26 - T 31-10-2018 IPR020608 RNA polymerase, subunit H/Rpb5, conserved site Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 DFR85_10560 ef729f122c3b4e8f65d4e34b08ffaa7d 193 PRINTS PR00097 Anthranilate synthase component II signature 49 58 1.8E-33 T 31-10-2018 DFR85_10560 ef729f122c3b4e8f65d4e34b08ffaa7d 193 PRINTS PR00097 Anthranilate synthase component II signature 79 90 1.8E-33 T 31-10-2018 DFR85_10560 ef729f122c3b4e8f65d4e34b08ffaa7d 193 PRINTS PR00097 Anthranilate synthase component II signature 125 137 1.8E-33 T 31-10-2018 DFR85_10560 ef729f122c3b4e8f65d4e34b08ffaa7d 193 PRINTS PR00097 Anthranilate synthase component II signature 4 18 1.8E-33 T 31-10-2018 DFR85_10560 ef729f122c3b4e8f65d4e34b08ffaa7d 193 PRINTS PR00097 Anthranilate synthase component II signature 169 182 1.8E-33 T 31-10-2018 DFR85_10560 ef729f122c3b4e8f65d4e34b08ffaa7d 193 PRINTS PR00097 Anthranilate synthase component II signature 104 112 1.8E-33 T 31-10-2018 DFR85_10560 ef729f122c3b4e8f65d4e34b08ffaa7d 193 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 5 192 2.4E-60 T 31-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 DFR85_10560 ef729f122c3b4e8f65d4e34b08ffaa7d 193 Gene3D G3DSA:3.40.50.880 1 193 2.7E-67 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like DFR85_10560 ef729f122c3b4e8f65d4e34b08ffaa7d 193 PRINTS PR00096 Glutamine amidotransferase superfamily signature 169 182 3.0E-14 T 31-10-2018 DFR85_10560 ef729f122c3b4e8f65d4e34b08ffaa7d 193 PRINTS PR00096 Glutamine amidotransferase superfamily signature 79 90 3.0E-14 T 31-10-2018 DFR85_10560 ef729f122c3b4e8f65d4e34b08ffaa7d 193 PRINTS PR00096 Glutamine amidotransferase superfamily signature 49 58 3.0E-14 T 31-10-2018 DFR85_10560 ef729f122c3b4e8f65d4e34b08ffaa7d 193 Pfam PF00117 Glutamine amidotransferase class-I 6 191 7.4E-48 T 31-10-2018 IPR017926 Glutamine amidotransferase DFR85_10560 ef729f122c3b4e8f65d4e34b08ffaa7d 193 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 46 60 5.9E-9 T 31-10-2018 DFR85_10560 ef729f122c3b4e8f65d4e34b08ffaa7d 193 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 79 95 5.9E-9 T 31-10-2018 DFR85_10560 ef729f122c3b4e8f65d4e34b08ffaa7d 193 SUPERFAMILY SSF52317 1 192 1.73E-53 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like DFR85_04290 68da213cc99e69ddd827025e4ebbb821 302 Gene3D G3DSA:3.40.50.720 1 301 3.2E-99 T 31-10-2018 DFR85_04290 68da213cc99e69ddd827025e4ebbb821 302 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 230 2.9E-50 T 31-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 DFR85_04290 68da213cc99e69ddd827025e4ebbb821 302 PRINTS PR01713 Nucleotide sugar epimerase signature 263 280 5.3E-8 T 31-10-2018 DFR85_04290 68da213cc99e69ddd827025e4ebbb821 302 PRINTS PR01713 Nucleotide sugar epimerase signature 202 217 5.3E-8 T 31-10-2018 DFR85_04290 68da213cc99e69ddd827025e4ebbb821 302 PRINTS PR01713 Nucleotide sugar epimerase signature 224 239 5.3E-8 T 31-10-2018 DFR85_04290 68da213cc99e69ddd827025e4ebbb821 302 SUPERFAMILY SSF51735 1 299 3.42E-86 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_08990 939fb1a4c27b1d5a355af9fe933b320e 54 SUPERFAMILY SSF89447 4 41 1.64E-10 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily DFR85_08990 939fb1a4c27b1d5a355af9fe933b320e 54 Gene3D G3DSA:2.10.260.10 1 48 8.8E-20 T 31-10-2018 DFR85_08990 939fb1a4c27b1d5a355af9fe933b320e 54 SMART SM00966 7 54 1.1E-8 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR85_08990 939fb1a4c27b1d5a355af9fe933b320e 54 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 7 43 3.2E-10 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR85_08990 939fb1a4c27b1d5a355af9fe933b320e 54 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 6 39 9.3E-14 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR85_02990 f80de912c9f980ee9e1a284ea80a323a 336 Pfam PF13360 PQQ-like domain 126 302 3.1E-13 T 31-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat DFR85_02990 f80de912c9f980ee9e1a284ea80a323a 336 Gene3D G3DSA:2.130.10.10 6 203 1.5E-23 T 31-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 DFR85_02990 f80de912c9f980ee9e1a284ea80a323a 336 Gene3D G3DSA:2.40.128.630 213 330 9.6E-12 T 31-10-2018 DFR85_02990 f80de912c9f980ee9e1a284ea80a323a 336 SMART SM00564 215 247 4.9 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DFR85_02990 f80de912c9f980ee9e1a284ea80a323a 336 SMART SM00564 173 200 41.0 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DFR85_02990 f80de912c9f980ee9e1a284ea80a323a 336 SMART SM00564 20 51 170.0 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DFR85_02990 f80de912c9f980ee9e1a284ea80a323a 336 SMART SM00564 107 143 300.0 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DFR85_02990 f80de912c9f980ee9e1a284ea80a323a 336 SMART SM00564 60 91 0.24 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DFR85_02990 f80de912c9f980ee9e1a284ea80a323a 336 SMART SM00564 262 297 560.0 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat DFR85_02990 f80de912c9f980ee9e1a284ea80a323a 336 SUPERFAMILY SSF50998 184 328 1.1E-14 T 31-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily DFR85_02990 f80de912c9f980ee9e1a284ea80a323a 336 SUPERFAMILY SSF50998 8 203 2.04E-25 T 31-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily DFR85_06320 05dc41c573de3373cc764d46e1ec3b90 473 Gene3D G3DSA:3.60.20.40 311 471 6.8E-25 T 31-10-2018 DFR85_06320 05dc41c573de3373cc764d46e1ec3b90 473 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 30 55 1.6E-13 T 31-10-2018 DFR85_06320 05dc41c573de3373cc764d46e1ec3b90 473 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 225 244 1.6E-13 T 31-10-2018 DFR85_06320 05dc41c573de3373cc764d46e1ec3b90 473 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 108 127 1.6E-13 T 31-10-2018 DFR85_06320 05dc41c573de3373cc764d46e1ec3b90 473 Pfam PF01019 Gamma-glutamyltranspeptidase 23 466 3.5E-76 T 31-10-2018 DFR85_06320 05dc41c573de3373cc764d46e1ec3b90 473 Gene3D G3DSA:1.10.246.230 212 310 1.1E-18 T 31-10-2018 DFR85_06320 05dc41c573de3373cc764d46e1ec3b90 473 SUPERFAMILY SSF56235 7 471 2.32E-99 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR85_14050 f48633afc4068ebad6c743e7596c7163 1010 Gene3D G3DSA:3.40.50.300 229 407 2.4E-6 T 31-10-2018 DFR85_09765 c13365d3d30a5a730378705c004073a6 541 Gene3D G3DSA:3.40.50.300 4 330 2.8E-91 T 31-10-2018 DFR85_09765 c13365d3d30a5a730378705c004073a6 541 Gene3D G3DSA:3.40.50.300 346 541 2.7E-52 T 31-10-2018 DFR85_09765 c13365d3d30a5a730378705c004073a6 541 SMART SM00491 381 524 2.6E-13 T 31-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 DFR85_09765 c13365d3d30a5a730378705c004073a6 541 SMART SM00488 7 207 0.0022 T 31-10-2018 IPR006554 Helicase-like, DEXD box c2 type GO:0004003|GO:0016818 DFR85_09765 c13365d3d30a5a730378705c004073a6 541 Gene3D G3DSA:1.10.275.30 187 292 2.8E-91 T 31-10-2018 DFR85_09765 c13365d3d30a5a730378705c004073a6 541 Pfam PF06733 DEAD_2 99 180 2.5E-14 T 31-10-2018 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 DFR85_09765 c13365d3d30a5a730378705c004073a6 541 Pfam PF13307 Helicase C-terminal domain 376 531 3.0E-25 T 31-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 DFR85_09765 c13365d3d30a5a730378705c004073a6 541 SUPERFAMILY SSF52540 20 518 2.42E-16 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_11695 d76f55e60a4735816687c1216a681e54 319 Pfam PF00756 Putative esterase 101 298 5.1E-10 T 31-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 DFR85_11695 d76f55e60a4735816687c1216a681e54 319 SUPERFAMILY SSF53474 24 301 6.6E-27 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold DFR85_12565 0e8470a12789283735ab6febe49d806f 438 SUPERFAMILY SSF103473 1 435 4.45E-72 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_12565 0e8470a12789283735ab6febe49d806f 438 Pfam PF07690 Major Facilitator Superfamily 36 389 1.2E-42 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_08460 a5cb92c6bc72f425d70347bd5656c87b 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 254 9.0E-46 T 31-10-2018 DFR85_08460 a5cb92c6bc72f425d70347bd5656c87b 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 2.3E-25 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_08460 a5cb92c6bc72f425d70347bd5656c87b 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 2.3E-25 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_08460 a5cb92c6bc72f425d70347bd5656c87b 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 2.3E-25 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_08460 a5cb92c6bc72f425d70347bd5656c87b 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 2.3E-25 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_08460 a5cb92c6bc72f425d70347bd5656c87b 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.3E-25 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_08460 a5cb92c6bc72f425d70347bd5656c87b 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 2.3E-25 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_08460 a5cb92c6bc72f425d70347bd5656c87b 259 SUPERFAMILY SSF51735 7 254 7.9E-61 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_08460 a5cb92c6bc72f425d70347bd5656c87b 259 Gene3D G3DSA:3.40.50.720 3 258 1.0E-53 T 31-10-2018 DFR85_05350 b415607ff4350b0290bea37382ac507a 103 Gene3D G3DSA:1.10.10.10 7 73 1.3E-5 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_05350 b415607ff4350b0290bea37382ac507a 103 SUPERFAMILY SSF46785 12 60 1.99E-5 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_05045 e1ced0ee708ed975344da833c0d5cd6f 299 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 23 253 3.9E-15 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 DFR85_05045 e1ced0ee708ed975344da833c0d5cd6f 299 Gene3D G3DSA:3.40.50.300 1 280 3.2E-19 T 31-10-2018 DFR85_05045 e1ced0ee708ed975344da833c0d5cd6f 299 SUPERFAMILY SSF52540 2 263 4.59E-19 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_05045 e1ced0ee708ed975344da833c0d5cd6f 299 SMART SM00382 20 277 0.0088 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_05865 677cafc3b785b4d307283aed2f623a0d 319 Pfam PF01384 Phosphate transporter family 19 276 4.8E-22 T 31-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 DFR85_10175 6619f986e30b17aca73bc878ae3063bc 218 PIRSF PIRSF002155 1 218 8.4E-50 T 31-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_10175 6619f986e30b17aca73bc878ae3063bc 218 Gene3D G3DSA:3.40.50.790 62 152 6.2E-59 T 31-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich DFR85_10175 6619f986e30b17aca73bc878ae3063bc 218 SUPERFAMILY SSF56808 2 215 4.32E-48 T 31-10-2018 IPR023674 Ribosomal protein L1-like DFR85_10175 6619f986e30b17aca73bc878ae3063bc 218 Pfam PF00687 Ribosomal protein L1p/L10e family 23 210 9.7E-31 T 31-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein DFR85_10175 6619f986e30b17aca73bc878ae3063bc 218 Gene3D G3DSA:3.30.190.20 21 211 6.2E-59 T 31-10-2018 DFR85_10175 6619f986e30b17aca73bc878ae3063bc 218 Hamap MF_01318_A 50S ribosomal protein L1 [rplA]. 4 216 30.954 T 31-10-2018 IPR023669 Ribosomal protein L1, archaea GO:0003723|GO:0003735|GO:0006412|GO:0015934 DFR85_10175 6619f986e30b17aca73bc878ae3063bc 218 ProSitePatterns PS01199 Ribosomal protein L1 signature. 117 136 - T 31-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_12695 d6c3b65bb4a474be1312464a70d25398 404 SUPERFAMILY SSF53850 24 362 4.79E-54 T 31-10-2018 DFR85_12695 d6c3b65bb4a474be1312464a70d25398 404 Gene3D G3DSA:3.40.190.10 24 327 3.8E-57 T 31-10-2018 DFR85_12695 d6c3b65bb4a474be1312464a70d25398 404 Pfam PF13416 Bacterial extracellular solute-binding protein 23 293 8.1E-18 T 31-10-2018 IPR006059 Bacterial extracellular solute-binding protein DFR85_12695 d6c3b65bb4a474be1312464a70d25398 404 Gene3D G3DSA:3.40.190.10 92 350 3.8E-57 T 31-10-2018 DFR85_15005 ac0a6bd62278bfdbe961bed6c233e74a 473 Pfam PF00083 Sugar (and other) transporter 54 463 1.8E-20 T 31-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 DFR85_15005 ac0a6bd62278bfdbe961bed6c233e74a 473 Gene3D G3DSA:1.20.1250.20 20 472 5.1E-53 T 31-10-2018 DFR85_15005 ac0a6bd62278bfdbe961bed6c233e74a 473 SUPERFAMILY SSF103473 28 465 9.81E-49 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_11745 1d0f384ff94636600e4da1519c07ac63 92 Gene3D G3DSA:1.10.10.10 1 80 2.0E-10 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_11745 1d0f384ff94636600e4da1519c07ac63 92 SUPERFAMILY SSF46785 1 79 1.21E-11 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_11745 1d0f384ff94636600e4da1519c07ac63 92 Pfam PF01022 Bacterial regulatory protein, arsR family 5 48 7.9E-8 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DFR85_13730 07c5625275d5ea33c2fe11c293625d6c 448 Gene3D G3DSA:3.40.50.300 25 183 6.5E-8 T 31-10-2018 DFR85_13730 07c5625275d5ea33c2fe11c293625d6c 448 SUPERFAMILY SSF52540 29 236 2.26E-7 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_08400 dea64c9f009a68d9dcd29e682e2abf07 139 Pfam PF02310 B12 binding domain 5 114 3.4E-24 T 31-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 DFR85_08400 dea64c9f009a68d9dcd29e682e2abf07 139 SUPERFAMILY SSF52242 3 128 1.06E-48 T 31-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 DFR85_08400 dea64c9f009a68d9dcd29e682e2abf07 139 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 3 131 1.3E-51 T 31-10-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 DFR85_08400 dea64c9f009a68d9dcd29e682e2abf07 139 Gene3D G3DSA:3.40.50.280 1 138 4.4E-58 T 31-10-2018 DFR85_11915 522908b781c83033a8b0b6831338dc9f 834 Gene3D G3DSA:3.20.19.10 603 832 2.1E-88 T 31-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 DFR85_11915 522908b781c83033a8b0b6831338dc9f 834 Gene3D G3DSA:3.30.499.10 348 544 1.2E-77 T 31-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 DFR85_11915 522908b781c83033a8b0b6831338dc9f 834 SUPERFAMILY SSF53732 13 580 1.7E-198 T 31-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 DFR85_11915 522908b781c83033a8b0b6831338dc9f 834 Pfam PF00330 Aconitase family (aconitate hydratase) 60 517 7.8E-168 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 DFR85_11915 522908b781c83033a8b0b6831338dc9f 834 ProSitePatterns PS00450 Aconitase family signature 1. 382 398 - T 31-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 DFR85_11915 522908b781c83033a8b0b6831338dc9f 834 Gene3D G3DSA:3.30.499.20 2 347 3.1E-145 T 31-10-2018 DFR85_11915 522908b781c83033a8b0b6831338dc9f 834 Pfam PF00694 Aconitase C-terminal domain 649 762 4.6E-34 T 31-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 DFR85_11915 522908b781c83033a8b0b6831338dc9f 834 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 18 829 0.0 T 31-10-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 DFR85_11915 522908b781c83033a8b0b6831338dc9f 834 Gene3D G3DSA:1.10.1440.20 545 602 4.8E-14 T 31-10-2018 DFR85_11915 522908b781c83033a8b0b6831338dc9f 834 PRINTS PR00415 Aconitase family signature 128 141 1.9E-42 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 DFR85_11915 522908b781c83033a8b0b6831338dc9f 834 PRINTS PR00415 Aconitase family signature 181 194 1.9E-42 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 DFR85_11915 522908b781c83033a8b0b6831338dc9f 834 PRINTS PR00415 Aconitase family signature 152 160 1.9E-42 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 DFR85_11915 522908b781c83033a8b0b6831338dc9f 834 PRINTS PR00415 Aconitase family signature 347 361 1.9E-42 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 DFR85_11915 522908b781c83033a8b0b6831338dc9f 834 PRINTS PR00415 Aconitase family signature 271 284 1.9E-42 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 DFR85_11915 522908b781c83033a8b0b6831338dc9f 834 PRINTS PR00415 Aconitase family signature 195 210 1.9E-42 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 DFR85_11915 522908b781c83033a8b0b6831338dc9f 834 PRINTS PR00415 Aconitase family signature 257 270 1.9E-42 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 DFR85_11915 522908b781c83033a8b0b6831338dc9f 834 PRINTS PR00415 Aconitase family signature 386 397 1.9E-42 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 DFR85_11915 522908b781c83033a8b0b6831338dc9f 834 PRINTS PR00415 Aconitase family signature 448 461 1.9E-42 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 DFR85_11915 522908b781c83033a8b0b6831338dc9f 834 ProSitePatterns PS01244 Aconitase family signature 2. 448 461 - T 31-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 DFR85_11915 522908b781c83033a8b0b6831338dc9f 834 SUPERFAMILY SSF52016 589 829 2.75E-64 T 31-10-2018 DFR85_06335 99187c9796b52b5b15858dd28e989534 394 Gene3D G3DSA:3.90.550.10 32 253 2.5E-50 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_06335 99187c9796b52b5b15858dd28e989534 394 Pfam PF13641 Glycosyltransferase like family 2 43 269 6.0E-37 T 31-10-2018 DFR85_06335 99187c9796b52b5b15858dd28e989534 394 SUPERFAMILY SSF53448 41 314 3.28E-58 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_04440 a8f98346160aa5e1f3f2d35dcef5d0ca 322 Gene3D G3DSA:3.40.50.2000 1 162 1.8E-11 T 31-10-2018 DFR85_04440 a8f98346160aa5e1f3f2d35dcef5d0ca 322 Gene3D G3DSA:3.40.50.2000 163 307 4.1E-11 T 31-10-2018 DFR85_04440 a8f98346160aa5e1f3f2d35dcef5d0ca 322 Pfam PF13692 Glycosyl transferases group 1 163 290 2.1E-20 T 31-10-2018 DFR85_04440 a8f98346160aa5e1f3f2d35dcef5d0ca 322 SUPERFAMILY SSF53756 5 321 3.14E-28 T 31-10-2018 DFR85_06220 c33293f8cd05c6dfc571f5122de1ba8e 188 Pfam PF01184 GPR1/FUN34/yaaH family 3 170 1.1E-42 T 31-10-2018 IPR000791 Acetate transporter GPR1/FUN34/SatP family GO:0016021 DFR85_06220 c33293f8cd05c6dfc571f5122de1ba8e 188 ProSitePatterns PS01114 GPR1/FUN34/yaaH family signature. 8 17 - T 31-10-2018 IPR000791 Acetate transporter GPR1/FUN34/SatP family GO:0016021 DFR85_08905 20221419cdceef6e88fe1086dfcf02c7 139 Gene3D G3DSA:3.30.230.10 2 139 7.4E-40 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup DFR85_08905 20221419cdceef6e88fe1086dfcf02c7 139 ProSitePatterns PS00360 Ribosomal protein S9 signature. 74 92 - T 31-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 DFR85_08905 20221419cdceef6e88fe1086dfcf02c7 139 Hamap MF_00532_A 30S ribosomal protein S9 [rpsI]. 9 139 32.881 T 31-10-2018 IPR019958 Ribosomal protein S9, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_08905 20221419cdceef6e88fe1086dfcf02c7 139 SUPERFAMILY SSF54211 9 139 1.48E-31 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold DFR85_08905 20221419cdceef6e88fe1086dfcf02c7 139 Pfam PF00380 Ribosomal protein S9/S16 15 139 1.1E-25 T 31-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 DFR85_08905 20221419cdceef6e88fe1086dfcf02c7 139 TIGRFAM TIGR03627 uS9_arch: ribosomal protein uS9 9 139 5.8E-56 T 31-10-2018 IPR019958 Ribosomal protein S9, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_03305 759a23cf9e9026cb8a3c5cbddc8ed6a5 214 Pfam PF04967 HTH DNA binding domain 151 202 2.2E-15 T 31-10-2018 IPR007050 Bacterioopsin activator-type, HTH domain DFR85_09175 bc2a5676f6b231b17243fec59a413b4a 351 TIGRFAM TIGR04337 AmmeMemoSam_rS: AmmeMemoRadiSam system radical SAM enzyme 10 349 3.1E-93 T 31-10-2018 IPR027596 AmmeMemoRadiSam system radical SAM enzyme DFR85_09175 bc2a5676f6b231b17243fec59a413b4a 351 PIRSF PIRSF004869 1 311 1.8E-89 T 31-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted DFR85_09175 bc2a5676f6b231b17243fec59a413b4a 351 Gene3D G3DSA:3.20.20.70 56 283 6.3E-31 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_09175 bc2a5676f6b231b17243fec59a413b4a 351 SMART SM00729 72 277 0.0036 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 DFR85_09175 bc2a5676f6b231b17243fec59a413b4a 351 Pfam PF04055 Radical SAM superfamily 79 233 9.2E-20 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR85_09175 bc2a5676f6b231b17243fec59a413b4a 351 SUPERFAMILY SSF102114 50 313 1.12E-34 T 31-10-2018 DFR85_01430 e6831bb71e5536e9f308c5a3aba952d3 374 Gene3D G3DSA:3.90.1150.10 12 358 2.5E-97 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 DFR85_01430 e6831bb71e5536e9f308c5a3aba952d3 374 SUPERFAMILY SSF53383 5 364 1.79E-74 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase DFR85_01430 e6831bb71e5536e9f308c5a3aba952d3 374 Pfam PF00266 Aminotransferase class-V 16 355 7.3E-52 T 31-10-2018 IPR000192 Aminotransferase class V domain DFR85_01430 e6831bb71e5536e9f308c5a3aba952d3 374 Gene3D G3DSA:3.40.640.10 27 280 2.5E-97 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR85_03435 894a93230adf57137a50d2d6d84652ee 220 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 17 199 2.3E-21 T 31-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 DFR85_03435 894a93230adf57137a50d2d6d84652ee 220 SUPERFAMILY SSF53790 14 200 4.32E-22 T 31-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 DFR85_03435 894a93230adf57137a50d2d6d84652ee 220 Gene3D G3DSA:3.40.1010.10 14 125 1.3E-11 T 31-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 DFR85_14805 388fc5e9a5876154c41c1737b5b77ef9 316 Gene3D G3DSA:3.40.50.970 1 182 1.4E-69 T 31-10-2018 DFR85_14805 388fc5e9a5876154c41c1737b5b77ef9 316 SUPERFAMILY SSF52922 179 314 1.19E-38 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 DFR85_14805 388fc5e9a5876154c41c1737b5b77ef9 316 Pfam PF02779 Transketolase, pyrimidine binding domain 1 161 1.5E-37 T 31-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain DFR85_14805 388fc5e9a5876154c41c1737b5b77ef9 316 Pfam PF02780 Transketolase, C-terminal domain 184 306 4.1E-36 T 31-10-2018 IPR033248 Transketolase, C-terminal domain DFR85_14805 388fc5e9a5876154c41c1737b5b77ef9 316 Gene3D G3DSA:3.40.50.920 183 316 4.5E-43 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 DFR85_14805 388fc5e9a5876154c41c1737b5b77ef9 316 SUPERFAMILY SSF52518 1 171 2.11E-59 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR85_14805 388fc5e9a5876154c41c1737b5b77ef9 316 SMART SM00861 1 162 4.4E-44 T 31-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain DFR85_11610 c04bc8ec60fcae81c8b860fdce92b99e 711 SUPERFAMILY SSF51011 603 709 4.17E-15 T 31-10-2018 DFR85_11610 c04bc8ec60fcae81c8b860fdce92b99e 711 SUPERFAMILY SSF51445 150 592 3.77E-128 T 31-10-2018 IPR017853 Glycoside hydrolase superfamily DFR85_11610 c04bc8ec60fcae81c8b860fdce92b99e 711 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 15 104 8.9E-15 T 31-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 DFR85_11610 c04bc8ec60fcae81c8b860fdce92b99e 711 Gene3D G3DSA:3.20.20.80 147 595 2.1E-177 T 31-10-2018 DFR85_11610 c04bc8ec60fcae81c8b860fdce92b99e 711 SUPERFAMILY SSF81296 10 157 2.46E-42 T 31-10-2018 IPR014756 Immunoglobulin E-set DFR85_11610 c04bc8ec60fcae81c8b860fdce92b99e 711 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 11 709 0.0 T 31-10-2018 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 DFR85_11610 c04bc8ec60fcae81c8b860fdce92b99e 711 Gene3D G3DSA:2.60.40.1180 605 711 8.3E-35 T 31-10-2018 IPR013780 Glycosyl hydrolase, all-beta DFR85_11610 c04bc8ec60fcae81c8b860fdce92b99e 711 SMART SM00642 144 581 7.7E-9 T 31-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 DFR85_11610 c04bc8ec60fcae81c8b860fdce92b99e 711 Pfam PF00128 Alpha amylase, catalytic domain 190 542 2.1E-13 T 31-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 DFR85_11610 c04bc8ec60fcae81c8b860fdce92b99e 711 Gene3D G3DSA:2.60.40.10 1 146 7.6E-48 T 31-10-2018 IPR013783 Immunoglobulin-like fold DFR85_04410 f1c19f52ef2afd3fca39161b0e221469 353 Gene3D G3DSA:3.90.550.10 30 237 5.4E-26 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_04410 f1c19f52ef2afd3fca39161b0e221469 353 SUPERFAMILY SSF53448 38 296 2.93E-31 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_04410 f1c19f52ef2afd3fca39161b0e221469 353 Pfam PF00535 Glycosyl transferase family 2 44 195 1.1E-20 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 DFR85_13335 4b1e238804c253a9fda77140cf698b1b 704 Pfam PF13091 PLD-like domain 576 697 2.0E-15 T 31-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 DFR85_13335 4b1e238804c253a9fda77140cf698b1b 704 Gene3D G3DSA:3.30.870.10 560 702 1.3E-15 T 31-10-2018 DFR85_13335 4b1e238804c253a9fda77140cf698b1b 704 SUPERFAMILY SSF56024 571 701 3.59E-14 T 31-10-2018 DFR85_08585 cd6689288eac4b0aada2ccbe2f2da8fc 301 TIGRFAM TIGR01475 ubiA_other: putative 4-hydroxybenzoate polyprenyltransferase 14 295 4.6E-90 T 31-10-2018 IPR006371 4-hydroxybenzoate polyprenyltransferase-related DFR85_08585 cd6689288eac4b0aada2ccbe2f2da8fc 301 Pfam PF01040 UbiA prenyltransferase family 31 269 1.6E-37 T 31-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 DFR85_08585 cd6689288eac4b0aada2ccbe2f2da8fc 301 Gene3D G3DSA:1.10.357.140 21 177 1.0E-40 T 31-10-2018 DFR85_08585 cd6689288eac4b0aada2ccbe2f2da8fc 301 Gene3D G3DSA:1.20.120.1780 178 301 2.6E-20 T 31-10-2018 DFR85_13135 30e95b661969d9dccee4db2e41da79f6 311 TIGRFAM TIGR03641 cas1_HMARI: CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP 1 309 6.8E-111 T 31-10-2018 IPR019858 CRISPR-associated protein Cas1, HMARI/TNEAP subtype GO:0004520|GO:0043571|GO:0046872 DFR85_13135 30e95b661969d9dccee4db2e41da79f6 311 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 2 307 8.2E-85 T 31-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 DFR85_13135 30e95b661969d9dccee4db2e41da79f6 311 Gene3D G3DSA:1.20.120.920 78 310 5.4E-62 T 31-10-2018 DFR85_13135 30e95b661969d9dccee4db2e41da79f6 311 Pfam PF01867 CRISPR associated protein Cas1 2 269 1.4E-75 T 31-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 DFR85_13135 30e95b661969d9dccee4db2e41da79f6 311 Gene3D G3DSA:3.100.10.20 1 76 7.0E-27 T 31-10-2018 DFR85_13135 30e95b661969d9dccee4db2e41da79f6 311 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 1 297 23.323 T 31-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 DFR85_05655 7e53988bae23ba6e50f8bbb5c0633dac 119 Gene3D G3DSA:3.40.1260.10 2 119 1.0E-16 T 31-10-2018 IPR027396 DsrEFH-like DFR85_05655 7e53988bae23ba6e50f8bbb5c0633dac 119 SUPERFAMILY SSF75169 6 119 5.38E-19 T 31-10-2018 IPR027396 DsrEFH-like DFR85_05655 7e53988bae23ba6e50f8bbb5c0633dac 119 Pfam PF02635 DsrE/DsrF-like family 7 119 1.0E-13 T 31-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein DFR85_02495 ca0f71690c560a3a84de2e09243cac6d 261 Gene3D G3DSA:1.10.10.10 130 177 2.8E-10 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_02495 ca0f71690c560a3a84de2e09243cac6d 261 SMART SM00344 131 218 4.8E-4 T 31-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 DFR85_02495 ca0f71690c560a3a84de2e09243cac6d 261 SMART SM00344 1 85 1.2E-4 T 31-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 DFR85_02495 ca0f71690c560a3a84de2e09243cac6d 261 SUPERFAMILY SSF46785 1 60 2.87E-12 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_02495 ca0f71690c560a3a84de2e09243cac6d 261 SUPERFAMILY SSF46785 130 184 1.44E-10 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_02495 ca0f71690c560a3a84de2e09243cac6d 261 Gene3D G3DSA:1.10.10.10 1 51 1.5E-14 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_02495 ca0f71690c560a3a84de2e09243cac6d 261 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 2.3E-11 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR85_02495 ca0f71690c560a3a84de2e09243cac6d 261 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 2.3E-11 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR85_02495 ca0f71690c560a3a84de2e09243cac6d 261 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 2.3E-11 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR85_02495 ca0f71690c560a3a84de2e09243cac6d 261 Pfam PF13412 Winged helix-turn-helix DNA-binding 130 176 2.5E-10 T 31-10-2018 DFR85_02495 ca0f71690c560a3a84de2e09243cac6d 261 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 47 2.0E-13 T 31-10-2018 DFR85_14400 f4aded483deb967e0143bb81983a1c5a 490 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 15 490 8.5E-150 T 31-10-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00640+1.2.1.27|MetaCyc: PWY-5642|Reactome: R-HSA-70895 DFR85_14400 f4aded483deb967e0143bb81983a1c5a 490 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 285 296 - T 31-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 DFR85_14400 f4aded483deb967e0143bb81983a1c5a 490 Gene3D G3DSA:3.40.605.10 34 468 2.6E-138 T 31-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 DFR85_14400 f4aded483deb967e0143bb81983a1c5a 490 SUPERFAMILY SSF53720 11 489 7.2E-134 T 31-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 DFR85_14400 f4aded483deb967e0143bb81983a1c5a 490 Pfam PF00171 Aldehyde dehydrogenase family 23 485 3.2E-136 T 31-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 DFR85_14400 f4aded483deb967e0143bb81983a1c5a 490 Gene3D G3DSA:3.40.309.10 260 460 2.6E-138 T 31-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 DFR85_06255 f099107e9a1d8c87ea88751e1aeb0a8c 308 Pfam PF07682 Sulphur oxygenase reductase 4 303 4.0E-142 T 31-10-2018 IPR011661 Sulphur oxygenase reductase KEGG: 00920+1.13.11.55|MetaCyc: PWY-5302 DFR85_06255 f099107e9a1d8c87ea88751e1aeb0a8c 308 SUPERFAMILY SSF54909 2 308 8.0E-139 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel DFR85_10165 d6229d0a158ef0aaf152434946e38c81 152 SUPERFAMILY SSF50104 57 149 2.33E-13 T 31-10-2018 IPR008991 Translation protein SH3-like domain superfamily DFR85_10165 d6229d0a158ef0aaf152434946e38c81 152 TIGRFAM TIGR00405 KOW_elon_Spt5: transcription elongation factor Spt5 9 148 3.9E-36 T 31-10-2018 IPR011590 Transcription elongation factor Spt5, archaeal GO:0003746 DFR85_10165 d6229d0a158ef0aaf152434946e38c81 152 Hamap MF_00950 Transcription elongation factor Spt5 [spt5]. 7 151 38.31 T 31-10-2018 IPR011590 Transcription elongation factor Spt5, archaeal GO:0003746 DFR85_10165 d6229d0a158ef0aaf152434946e38c81 152 Pfam PF03439 Early transcription elongation factor of RNA pol II, NGN section 7 87 1.1E-23 T 31-10-2018 IPR005100 NGN domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 DFR85_10165 d6229d0a158ef0aaf152434946e38c81 152 SMART SM00738 5 90 1.1E-22 T 31-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 DFR85_10165 d6229d0a158ef0aaf152434946e38c81 152 SMART SM00739 95 122 9.3E-5 T 31-10-2018 IPR005824 KOW DFR85_10165 d6229d0a158ef0aaf152434946e38c81 152 Pfam PF00467 KOW motif 98 127 2.0E-5 T 31-10-2018 IPR005824 KOW DFR85_10165 d6229d0a158ef0aaf152434946e38c81 152 Gene3D G3DSA:2.30.30.30 94 152 1.2E-19 T 31-10-2018 IPR014722 Ribosomal protein L2, domain 2 DFR85_10165 d6229d0a158ef0aaf152434946e38c81 152 Gene3D G3DSA:3.30.70.940 8 93 6.0E-26 T 31-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 DFR85_11210 87c1349dab56783f4f29f16807da2385 168 SUPERFAMILY SSF52540 1 167 5.05E-14 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_11210 87c1349dab56783f4f29f16807da2385 168 Pfam PF13207 AAA domain 1 118 7.6E-9 T 31-10-2018 DFR85_11210 87c1349dab56783f4f29f16807da2385 168 Gene3D G3DSA:3.40.50.300 1 168 3.6E-39 T 31-10-2018 DFR85_01100 7fc5b6c34f10d189a3c985a6767d0c62 217 SUPERFAMILY SSF48371 13 212 4.8E-6 T 31-10-2018 IPR016024 Armadillo-type fold DFR85_00420 8841edcb4c5fe7ce11d831d3ecbc6b47 382 Pfam PF07690 Major Facilitator Superfamily 16 310 2.1E-19 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_00420 8841edcb4c5fe7ce11d831d3ecbc6b47 382 Gene3D G3DSA:1.20.1250.20 8 190 1.8E-13 T 31-10-2018 DFR85_00420 8841edcb4c5fe7ce11d831d3ecbc6b47 382 SUPERFAMILY SSF103473 11 379 3.14E-34 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_00420 8841edcb4c5fe7ce11d831d3ecbc6b47 382 Gene3D G3DSA:1.20.1250.20 193 381 3.6E-11 T 31-10-2018 DFR85_12260 1469a77ad6fc25e0150e999ecbb1fcfa 311 Gene3D G3DSA:3.30.1490.20 1 175 1.4E-37 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 DFR85_12260 1469a77ad6fc25e0150e999ecbb1fcfa 311 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 16 306 1.0E-72 T 31-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 DFR85_12260 1469a77ad6fc25e0150e999ecbb1fcfa 311 Gene3D G3DSA:3.30.470.20 176 310 1.0E-34 T 31-10-2018 DFR85_12260 1469a77ad6fc25e0150e999ecbb1fcfa 311 SUPERFAMILY SSF56059 2 306 6.98E-65 T 31-10-2018 DFR85_00675 b204e163a3f8196af44726d0d0a519b6 236 Pfam PF02597 ThiS family 6 86 5.6E-11 T 31-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 DFR85_00675 b204e163a3f8196af44726d0d0a519b6 236 SUPERFAMILY SSF54285 6 86 7.29E-10 T 31-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp DFR85_00675 b204e163a3f8196af44726d0d0a519b6 236 Gene3D G3DSA:3.90.1170.40 87 231 4.9E-29 T 31-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 DFR85_00675 b204e163a3f8196af44726d0d0a519b6 236 SUPERFAMILY SSF54690 98 226 1.7E-29 T 31-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 DFR85_00675 b204e163a3f8196af44726d0d0a519b6 236 TIGRFAM TIGR01687 moaD_arch: MoaD family protein 4 86 2.0E-22 T 31-10-2018 IPR010038 MoaD, archaeal-type DFR85_00675 b204e163a3f8196af44726d0d0a519b6 236 Pfam PF02391 MoaE protein 106 203 9.7E-18 T 31-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 DFR85_00675 b204e163a3f8196af44726d0d0a519b6 236 Gene3D G3DSA:3.10.20.30 4 86 9.5E-12 T 31-10-2018 IPR012675 Beta-grasp domain superfamily DFR85_10125 6f1cdc28380cb03a297a9fdfba345281 116 Gene3D G3DSA:1.10.8.140 31 111 1.5E-26 T 31-10-2018 IPR036883 PDCD5-like superfamily GO:0003677 DFR85_10125 6f1cdc28380cb03a297a9fdfba345281 116 Pfam PF01984 Double-stranded DNA-binding domain 11 112 2.6E-26 T 31-10-2018 IPR002836 PDCD5-like GO:0003677 DFR85_10125 6f1cdc28380cb03a297a9fdfba345281 116 SUPERFAMILY SSF46950 13 109 1.1E-26 T 31-10-2018 IPR036883 PDCD5-like superfamily GO:0003677 DFR85_10125 6f1cdc28380cb03a297a9fdfba345281 116 Hamap MF_00026 DNA-binding protein . 8 110 15.541 T 31-10-2018 IPR022889 DNA-binding protein, archaeal DFR85_10125 6f1cdc28380cb03a297a9fdfba345281 116 PIRSF PIRSF015730 4 116 1.1E-33 T 31-10-2018 IPR002836 PDCD5-like GO:0003677 DFR85_10780 11bbd132b462890e1d3bd1c5807ff107 292 SUPERFAMILY SSF57783 2 46 6.8E-17 T 31-10-2018 DFR85_10780 11bbd132b462890e1d3bd1c5807ff107 292 Gene3D G3DSA:1.10.472.10 200 292 2.0E-17 T 31-10-2018 DFR85_10780 11bbd132b462890e1d3bd1c5807ff107 292 PRINTS PR00685 Transcription initiation factor IIB signature 148 167 7.3E-34 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 DFR85_10780 11bbd132b462890e1d3bd1c5807ff107 292 PRINTS PR00685 Transcription initiation factor IIB signature 15 35 7.3E-34 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 DFR85_10780 11bbd132b462890e1d3bd1c5807ff107 292 PRINTS PR00685 Transcription initiation factor IIB signature 37 50 7.3E-34 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 DFR85_10780 11bbd132b462890e1d3bd1c5807ff107 292 PRINTS PR00685 Transcription initiation factor IIB signature 204 222 7.3E-34 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 DFR85_10780 11bbd132b462890e1d3bd1c5807ff107 292 PRINTS PR00685 Transcription initiation factor IIB signature 238 254 7.3E-34 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 DFR85_10780 11bbd132b462890e1d3bd1c5807ff107 292 PRINTS PR00685 Transcription initiation factor IIB signature 270 284 7.3E-34 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 DFR85_10780 11bbd132b462890e1d3bd1c5807ff107 292 PRINTS PR00685 Transcription initiation factor IIB signature 50 71 7.3E-34 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 DFR85_10780 11bbd132b462890e1d3bd1c5807ff107 292 Pfam PF00382 Transcription factor TFIIB repeat 205 275 2.0E-9 T 31-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 DFR85_10780 11bbd132b462890e1d3bd1c5807ff107 292 SUPERFAMILY SSF47954 199 290 4.68E-19 T 31-10-2018 IPR036915 Cyclin-like superfamily DFR85_10780 11bbd132b462890e1d3bd1c5807ff107 292 Gene3D G3DSA:1.10.472.170 1 189 5.2E-46 T 31-10-2018 DFR85_10780 11bbd132b462890e1d3bd1c5807ff107 292 SUPERFAMILY SSF47954 101 188 1.23E-12 T 31-10-2018 IPR036915 Cyclin-like superfamily DFR85_10780 11bbd132b462890e1d3bd1c5807ff107 292 Pfam PF08271 TFIIB zinc-binding 2 42 2.8E-19 T 31-10-2018 IPR013137 Zinc finger, TFIIB-type DFR85_01560 8143a09f737fa3487f0ed237778552aa 559 SUPERFAMILY SSF52016 380 558 7.38E-61 T 31-10-2018 DFR85_01560 8143a09f737fa3487f0ed237778552aa 559 Pfam PF00920 Dehydratase family 36 555 2.7E-211 T 31-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 DFR85_01560 8143a09f737fa3487f0ed237778552aa 559 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 5 558 46.574 T 31-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 DFR85_01560 8143a09f737fa3487f0ed237778552aa 559 SUPERFAMILY SSF143975 4 379 8.76E-134 T 31-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 DFR85_01560 8143a09f737fa3487f0ed237778552aa 559 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 124 134 - T 31-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 DFR85_01560 8143a09f737fa3487f0ed237778552aa 559 Gene3D G3DSA:3.50.30.80 380 529 1.8E-54 T 31-10-2018 DFR85_01560 8143a09f737fa3487f0ed237778552aa 559 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 558 9.3E-220 T 31-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 DFR85_01560 8143a09f737fa3487f0ed237778552aa 559 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 466 477 - T 31-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 DFR85_02630 67e95b9c340dc93fc1b7ceb47978e879 79 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 3 45 1.4E-12 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR85_02630 67e95b9c340dc93fc1b7ceb47978e879 79 SUPERFAMILY SSF89447 3 45 1.24E-11 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily DFR85_02630 67e95b9c340dc93fc1b7ceb47978e879 79 SMART SM00966 3 48 1.9E-12 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR85_02630 67e95b9c340dc93fc1b7ceb47978e879 79 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 3 43 1.3E-15 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR85_02630 67e95b9c340dc93fc1b7ceb47978e879 79 Gene3D G3DSA:2.10.260.10 2 41 5.0E-12 T 31-10-2018 DFR85_01080 cf44dca935d73feba79556f63db9a1ff 146 SUPERFAMILY SSF55729 4 132 9.96E-25 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase DFR85_01080 cf44dca935d73feba79556f63db9a1ff 146 Pfam PF00583 Acetyltransferase (GNAT) family 35 130 1.9E-14 T 31-10-2018 IPR000182 GNAT domain DFR85_01080 cf44dca935d73feba79556f63db9a1ff 146 Gene3D G3DSA:3.40.630.30 2 144 5.0E-37 T 31-10-2018 DFR85_10835 e7b1a4c1f43868d42a008b6405380fcb 471 Gene3D G3DSA:3.90.1300.10 3 468 1.0E-171 T 31-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DFR85_10835 e7b1a4c1f43868d42a008b6405380fcb 471 Pfam PF01425 Amidase 19 451 3.0E-144 T 31-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DFR85_10835 e7b1a4c1f43868d42a008b6405380fcb 471 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 9 462 2.1E-179 T 31-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DFR85_10835 e7b1a4c1f43868d42a008b6405380fcb 471 SUPERFAMILY SSF75304 9 462 1.7E-141 T 31-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DFR85_10835 e7b1a4c1f43868d42a008b6405380fcb 471 ProSitePatterns PS00571 Amidases signature. 141 172 - T 31-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 DFR85_10835 e7b1a4c1f43868d42a008b6405380fcb 471 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 5 463 86.403 T 31-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 DFR85_02345 1e5d1f84586b15181616b14aaa377740 265 Pfam PF01841 Transglutaminase-like superfamily 117 217 5.5E-20 T 31-10-2018 IPR002931 Transglutaminase-like DFR85_02345 1e5d1f84586b15181616b14aaa377740 265 SMART SM00460 160 219 9.1E-16 T 31-10-2018 IPR002931 Transglutaminase-like DFR85_02345 1e5d1f84586b15181616b14aaa377740 265 Gene3D G3DSA:3.10.620.30 75 251 5.2E-41 T 31-10-2018 DFR85_02345 1e5d1f84586b15181616b14aaa377740 265 SUPERFAMILY SSF54001 13 247 3.22E-35 T 31-10-2018 IPR038765 Papain-like cysteine peptidase superfamily DFR85_02345 1e5d1f84586b15181616b14aaa377740 265 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 8 84 9.2E-13 T 31-10-2018 IPR013589 Bacterial transglutaminase-like, N-terminal DFR85_06765 7053e4411cf0c5b0eaf7710074e1745d 179 SUPERFAMILY SSF51283 1 170 3.66E-46 T 31-10-2018 IPR036157 dUTPase-like superfamily DFR85_06765 7053e4411cf0c5b0eaf7710074e1745d 179 Pfam PF00692 dUTPase 60 167 4.1E-26 T 31-10-2018 IPR029054 dUTPase-like DFR85_06765 7053e4411cf0c5b0eaf7710074e1745d 179 Gene3D G3DSA:2.70.40.10 1 175 4.6E-48 T 31-10-2018 IPR036157 dUTPase-like superfamily DFR85_06765 7053e4411cf0c5b0eaf7710074e1745d 179 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 2 170 1.4E-55 T 31-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 DFR85_06765 7053e4411cf0c5b0eaf7710074e1745d 179 Hamap MF_00146 dCTP deaminase [dcd]. 1 171 31.639 T 31-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 DFR85_12315 0e6c4e5884e26e013450b9bc2586d3bb 503 Gene3D G3DSA:2.40.110.10 147 275 2.3E-39 T 31-10-2018 DFR85_12315 0e6c4e5884e26e013450b9bc2586d3bb 503 Gene3D G3DSA:1.10.3140.10 2 145 4.3E-42 T 31-10-2018 DFR85_12315 0e6c4e5884e26e013450b9bc2586d3bb 503 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 282 477 1.1E-63 T 31-10-2018 IPR024719 HpaB/PvcC/4-BUDH C-terminal DFR85_12315 0e6c4e5884e26e013450b9bc2586d3bb 503 SUPERFAMILY SSF56645 3 274 4.32E-75 T 31-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 DFR85_12315 0e6c4e5884e26e013450b9bc2586d3bb 503 Gene3D G3DSA:1.20.140.10 278 479 4.8E-71 T 31-10-2018 DFR85_12315 0e6c4e5884e26e013450b9bc2586d3bb 503 SUPERFAMILY SSF47203 265 478 4.18E-64 T 31-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 DFR85_12315 0e6c4e5884e26e013450b9bc2586d3bb 503 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 5 274 3.6E-90 T 31-10-2018 IPR024674 HpaB/PvcC/4-BUDH N-terminal DFR85_12315 0e6c4e5884e26e013450b9bc2586d3bb 503 PIRSF PIRSF000331 1 487 3.3E-163 T 31-10-2018 IPR004925 HpaB/PvcC/4-BUDH DFR85_07405 57471b77509e724c413e56b58afc560a 195 TIGRFAM TIGR03634 arc_protsome_B: proteasome endopeptidase complex, archaeal, beta subunit 6 187 6.1E-69 T 31-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 DFR85_07405 57471b77509e724c413e56b58afc560a 195 PRINTS PR00141 Proteasome component signature 13 28 4.4E-8 T 31-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 DFR85_07405 57471b77509e724c413e56b58afc560a 195 PRINTS PR00141 Proteasome component signature 169 180 4.4E-8 T 31-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 DFR85_07405 57471b77509e724c413e56b58afc560a 195 PRINTS PR00141 Proteasome component signature 144 155 4.4E-8 T 31-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 DFR85_07405 57471b77509e724c413e56b58afc560a 195 PRINTS PR00141 Proteasome component signature 133 144 4.4E-8 T 31-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 DFR85_07405 57471b77509e724c413e56b58afc560a 195 SUPERFAMILY SSF56235 6 188 2.65E-52 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR85_07405 57471b77509e724c413e56b58afc560a 195 Hamap MF_02113_A Proteasome subunit beta [prcB]. 1 195 33.967 T 31-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 DFR85_07405 57471b77509e724c413e56b58afc560a 195 Gene3D G3DSA:3.60.20.10 3 195 1.5E-54 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR85_07405 57471b77509e724c413e56b58afc560a 195 Pfam PF00227 Proteasome subunit 6 183 8.2E-47 T 31-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 DFR85_15370 3cb51045c157502d26807adfd6957b23 440 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 298 389 1.1E-11 T 31-10-2018 IPR023885 4Fe4S-binding SPASM domain DFR85_15370 3cb51045c157502d26807adfd6957b23 440 Gene3D G3DSA:3.20.20.70 31 409 1.0E-62 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_15370 3cb51045c157502d26807adfd6957b23 440 Pfam PF13353 4Fe-4S single cluster domain 41 157 7.9E-11 T 31-10-2018 DFR85_15370 3cb51045c157502d26807adfd6957b23 440 Pfam PF04055 Radical SAM superfamily 38 186 6.1E-8 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR85_15370 3cb51045c157502d26807adfd6957b23 440 Pfam PF13186 Iron-sulfur cluster-binding domain 298 361 5.5E-6 T 31-10-2018 IPR023885 4Fe4S-binding SPASM domain DFR85_15370 3cb51045c157502d26807adfd6957b23 440 SUPERFAMILY SSF102114 31 367 7.46E-37 T 31-10-2018 DFR85_14970 43b7369b08a349fb23dd3ae4105ee0fe 258 Gene3D G3DSA:3.90.226.10 1 198 9.6E-58 T 31-10-2018 DFR85_14970 43b7369b08a349fb23dd3ae4105ee0fe 258 SUPERFAMILY SSF52096 6 257 1.08E-74 T 31-10-2018 IPR029045 ClpP/crotonase-like domain superfamily DFR85_14970 43b7369b08a349fb23dd3ae4105ee0fe 258 Pfam PF00378 Enoyl-CoA hydratase/isomerase 16 257 1.5E-54 T 31-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 DFR85_14970 43b7369b08a349fb23dd3ae4105ee0fe 258 Gene3D G3DSA:1.10.12.10 201 258 1.2E-18 T 31-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal DFR85_08755 09b3945711be3768b6cfa875899fe9ca 126 SUPERFAMILY SSF55315 4 120 1.09E-39 T 31-10-2018 IPR029064 50S ribosomal protein L30e-like DFR85_08755 09b3945711be3768b6cfa875899fe9ca 126 TIGRFAM TIGR03677 eL8_ribo: ribosomal protein eL8 6 120 8.3E-55 T 31-10-2018 IPR022481 Ribosomal protein L7Ae, archaea GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_08755 09b3945711be3768b6cfa875899fe9ca 126 Hamap MF_00326 50S ribosomal protein L7Ae [rpl7ae]. 3 122 32.66 T 31-10-2018 IPR022481 Ribosomal protein L7Ae, archaea GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_08755 09b3945711be3768b6cfa875899fe9ca 126 Gene3D G3DSA:3.30.1330.30 1 126 7.7E-45 T 31-10-2018 IPR029064 50S ribosomal protein L30e-like DFR85_08755 09b3945711be3768b6cfa875899fe9ca 126 PRINTS PR00884 Ribosomal protein HS6 signature 6 17 1.0E-29 T 31-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_08755 09b3945711be3768b6cfa875899fe9ca 126 PRINTS PR00884 Ribosomal protein HS6 signature 50 61 1.0E-29 T 31-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_08755 09b3945711be3768b6cfa875899fe9ca 126 PRINTS PR00884 Ribosomal protein HS6 signature 91 107 1.0E-29 T 31-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_08755 09b3945711be3768b6cfa875899fe9ca 126 PRINTS PR00884 Ribosomal protein HS6 signature 40 50 1.0E-29 T 31-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_08755 09b3945711be3768b6cfa875899fe9ca 126 PRINTS PR00884 Ribosomal protein HS6 signature 77 87 1.0E-29 T 31-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_08755 09b3945711be3768b6cfa875899fe9ca 126 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 77 91 5.7E-20 T 31-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family DFR85_08755 09b3945711be3768b6cfa875899fe9ca 126 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 67 77 5.7E-20 T 31-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family DFR85_08755 09b3945711be3768b6cfa875899fe9ca 126 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 51 64 5.7E-20 T 31-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family DFR85_08755 09b3945711be3768b6cfa875899fe9ca 126 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 32 46 5.7E-20 T 31-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family DFR85_08755 09b3945711be3768b6cfa875899fe9ca 126 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 18 109 1.8E-31 T 31-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 DFR85_00025 ddb6e5ea05a47af6a8818d41e03930a4 326 Gene3D G3DSA:2.102.10.10 86 295 3.5E-54 T 31-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 DFR85_00025 ddb6e5ea05a47af6a8818d41e03930a4 326 Pfam PF00355 Rieske [2Fe-2S] domain 142 250 7.4E-9 T 31-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DFR85_00025 ddb6e5ea05a47af6a8818d41e03930a4 326 SUPERFAMILY SSF50022 91 279 1.92E-29 T 31-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 DFR85_14670 b07bac9cb635b84789f94a662f854265 509 SUPERFAMILY SSF56801 30 508 8.37E-129 T 31-10-2018 DFR85_14670 b07bac9cb635b84789f94a662f854265 509 Gene3D G3DSA:3.30.300.30 409 509 8.4E-26 T 31-10-2018 DFR85_14670 b07bac9cb635b84789f94a662f854265 509 Pfam PF13193 AMP-binding enzyme C-terminal domain 422 500 5.9E-21 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain DFR85_14670 b07bac9cb635b84789f94a662f854265 509 Gene3D G3DSA:3.40.50.12780 13 408 4.3E-93 T 31-10-2018 DFR85_14670 b07bac9cb635b84789f94a662f854265 509 ProSitePatterns PS00455 Putative AMP-binding domain signature. 174 185 - T 31-10-2018 IPR020845 AMP-binding, conserved site DFR85_14670 b07bac9cb635b84789f94a662f854265 509 Pfam PF00501 AMP-binding enzyme 31 414 3.8E-76 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 DFR85_07040 3963587b75743803d02c442cf5d4d379 176 Gene3D G3DSA:3.30.1440.10 1 176 9.8E-68 T 31-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07040 3963587b75743803d02c442cf5d4d379 176 Hamap MF_01333_A 50S ribosomal protein L5 [rplE]. 9 176 41.075 T 31-10-2018 IPR022804 Ribosomal protein L5, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_07040 3963587b75743803d02c442cf5d4d379 176 PIRSF PIRSF002161 1 175 3.9E-56 T 31-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07040 3963587b75743803d02c442cf5d4d379 176 Pfam PF00281 Ribosomal protein L5 10 63 8.7E-23 T 31-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07040 3963587b75743803d02c442cf5d4d379 176 SUPERFAMILY SSF55282 9 174 6.59E-57 T 31-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07040 3963587b75743803d02c442cf5d4d379 176 Pfam PF00673 ribosomal L5P family C-terminus 67 166 1.4E-24 T 31-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_10235 ae981fd8a5703b2ec4ef5f38c1026fae 136 SUPERFAMILY SSF52402 13 136 1.59E-21 T 31-10-2018 DFR85_10235 ae981fd8a5703b2ec4ef5f38c1026fae 136 Pfam PF00582 Universal stress protein family 13 136 1.2E-14 T 31-10-2018 IPR006016 UspA DFR85_10235 ae981fd8a5703b2ec4ef5f38c1026fae 136 Gene3D G3DSA:3.40.50.620 10 136 4.2E-21 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR85_10235 ae981fd8a5703b2ec4ef5f38c1026fae 136 PRINTS PR01438 Universal stress protein signature 13 31 4.8E-14 T 31-10-2018 IPR006015 Universal stress protein A DFR85_10235 ae981fd8a5703b2ec4ef5f38c1026fae 136 PRINTS PR01438 Universal stress protein signature 96 108 4.8E-14 T 31-10-2018 IPR006015 Universal stress protein A DFR85_10235 ae981fd8a5703b2ec4ef5f38c1026fae 136 PRINTS PR01438 Universal stress protein signature 114 136 4.8E-14 T 31-10-2018 IPR006015 Universal stress protein A DFR85_04845 42943448fe4ebfe1b38ae051d11c7323 270 SUPERFAMILY SSF52540 16 82 2.09E-5 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_04845 42943448fe4ebfe1b38ae051d11c7323 270 Gene3D G3DSA:3.40.50.300 1 237 3.8E-7 T 31-10-2018 DFR85_04845 42943448fe4ebfe1b38ae051d11c7323 270 Pfam PF13175 AAA ATPase domain 2 107 3.5E-8 T 31-10-2018 DFR85_06420 115a4f4d9ed15502d5e553688c045d78 303 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 290 59.103 T 31-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 DFR85_06420 115a4f4d9ed15502d5e553688c045d78 303 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 4 277 1.3E-55 T 31-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 DFR85_06420 115a4f4d9ed15502d5e553688c045d78 303 Pfam PF03186 CobD/Cbib protein 6 268 3.1E-70 T 31-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 DFR85_01600 3686d4c43c5f060b5d109594daf4e4d1 97 Gene3D G3DSA:3.30.1360.20 2 97 3.0E-32 T 31-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 DFR85_01600 3686d4c43c5f060b5d109594daf4e4d1 97 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 3 91 2.7E-30 T 31-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 DFR85_01600 3686d4c43c5f060b5d109594daf4e4d1 97 SUPERFAMILY SSF55248 1 91 1.1E-31 T 31-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 DFR85_01600 3686d4c43c5f060b5d109594daf4e4d1 97 Hamap MF_00434 Putative pterin-4-alpha-carbinolamine dehydratase. 1 92 23.603 T 31-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 DFR85_09420 a08fd7a73036f033f6df65cd708c0be5 135 Gene3D G3DSA:3.10.20.400 9 106 1.4E-33 T 31-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 DFR85_09420 a08fd7a73036f033f6df65cd708c0be5 135 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 16 119 28.711 T 31-10-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 DFR85_09420 a08fd7a73036f033f6df65cd708c0be5 135 SUPERFAMILY SSF141734 27 120 4.58E-40 T 31-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 DFR85_09420 a08fd7a73036f033f6df65cd708c0be5 135 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 42 115 2.6E-31 T 31-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 DFR85_09420 a08fd7a73036f033f6df65cd708c0be5 135 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 66 115 2.0E-19 T 31-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 DFR85_03870 a0e9ed19e9a68edbab9ffe0d894c6e0d 311 Pfam PF01670 Glycosyl hydrolase family 12 70 287 1.1E-14 T 31-10-2018 IPR002594 Glycoside hydrolase family 12 GO:0000272|GO:0008810 DFR85_03870 a0e9ed19e9a68edbab9ffe0d894c6e0d 311 SUPERFAMILY SSF49899 50 296 1.61E-32 T 31-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily DFR85_03870 a0e9ed19e9a68edbab9ffe0d894c6e0d 311 Gene3D G3DSA:2.60.120.180 48 308 3.0E-44 T 31-10-2018 IPR013319 Glycoside hydrolase family 11/12 GO:0004553 MetaCyc: PWY-6717|MetaCyc: PWY-6784 DFR85_14655 c0ce302120632b201bbc03341385e234 57 Pfam PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family 3 56 8.1E-10 T 31-10-2018 IPR007269 Isoprenylcysteine carboxyl methyltransferase GO:0004671|GO:0006481|GO:0016021 Reactome: R-HSA-163841 DFR85_14655 c0ce302120632b201bbc03341385e234 57 Gene3D G3DSA:1.20.120.1630 2 57 3.0E-11 T 31-10-2018 DFR85_03655 0e8f2cffd8c5913a3e6a1e3a25951921 427 Pfam PF13353 4Fe-4S single cluster domain 39 155 1.0E-9 T 31-10-2018 DFR85_03655 0e8f2cffd8c5913a3e6a1e3a25951921 427 Pfam PF13186 Iron-sulfur cluster-binding domain 293 357 3.1E-6 T 31-10-2018 IPR023885 4Fe4S-binding SPASM domain DFR85_03655 0e8f2cffd8c5913a3e6a1e3a25951921 427 SUPERFAMILY SSF102114 29 363 4.45E-41 T 31-10-2018 DFR85_03655 0e8f2cffd8c5913a3e6a1e3a25951921 427 Gene3D G3DSA:3.20.20.70 29 404 5.5E-63 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_03655 0e8f2cffd8c5913a3e6a1e3a25951921 427 Pfam PF04055 Radical SAM superfamily 36 183 8.2E-11 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR85_03655 0e8f2cffd8c5913a3e6a1e3a25951921 427 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 293 365 1.7E-11 T 31-10-2018 IPR023885 4Fe4S-binding SPASM domain DFR85_15615 bd30d1f08e4c96b7cd8c0c0a9c98acfc 244 Pfam PF00378 Enoyl-CoA hydratase/isomerase 4 241 7.5E-48 T 31-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 DFR85_15615 bd30d1f08e4c96b7cd8c0c0a9c98acfc 244 SUPERFAMILY SSF52096 1 241 1.9E-59 T 31-10-2018 IPR029045 ClpP/crotonase-like domain superfamily DFR85_15615 bd30d1f08e4c96b7cd8c0c0a9c98acfc 244 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 95 115 - T 31-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 DFR85_15615 bd30d1f08e4c96b7cd8c0c0a9c98acfc 244 Gene3D G3DSA:3.90.226.10 1 243 5.2E-58 T 31-10-2018 DFR85_02755 7b14e59847a91dd44a499700dc6efc98 533 PIRSF PIRSF006060 2 532 1.1E-31 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_02755 7b14e59847a91dd44a499700dc6efc98 533 Gene3D G3DSA:1.20.1740.10 20 524 5.4E-21 T 31-10-2018 DFR85_02755 7b14e59847a91dd44a499700dc6efc98 533 Pfam PF13520 Amino acid permease 26 499 4.2E-18 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_13865 12efb16513873d86e2cb80b4696203f2 394 Gene3D G3DSA:3.30.70.20 31 190 1.3E-36 T 31-10-2018 DFR85_13865 12efb16513873d86e2cb80b4696203f2 394 Pfam PF13247 4Fe-4S dicluster domain 48 135 7.1E-18 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR85_13865 12efb16513873d86e2cb80b4696203f2 394 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 83 94 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR85_13865 12efb16513873d86e2cb80b4696203f2 394 SUPERFAMILY SSF54862 3 164 4.19E-48 T 31-10-2018 DFR85_12690 8c064a321ca767f37a10e7338752a92e 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 279 7.6E-19 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 DFR85_12690 8c064a321ca767f37a10e7338752a92e 291 SUPERFAMILY SSF160964 9 45 3.53E-5 T 31-10-2018 DFR85_12690 8c064a321ca767f37a10e7338752a92e 291 Gene3D G3DSA:1.10.3720.10 48 288 4.4E-71 T 31-10-2018 IPR035906 MetI-like superfamily DFR85_12690 8c064a321ca767f37a10e7338752a92e 291 SUPERFAMILY SSF161098 51 279 1.27E-63 T 31-10-2018 IPR035906 MetI-like superfamily DFR85_09415 1782a78266cf8e5d5ed6d080fa6410d7 456 TIGRFAM TIGR00414 serS: serine--tRNA ligase 7 438 5.1E-141 T 31-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 DFR85_09415 1782a78266cf8e5d5ed6d080fa6410d7 456 SUPERFAMILY SSF55681 162 438 1.84E-74 T 31-10-2018 DFR85_09415 1782a78266cf8e5d5ed6d080fa6410d7 456 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 242 421 1.1E-36 T 31-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR85_09415 1782a78266cf8e5d5ed6d080fa6410d7 456 Gene3D G3DSA:1.10.287.40 6 105 1.8E-21 T 31-10-2018 DFR85_09415 1782a78266cf8e5d5ed6d080fa6410d7 456 PIRSF PIRSF001529 5 446 2.6E-132 T 31-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 DFR85_09415 1782a78266cf8e5d5ed6d080fa6410d7 456 Hamap MF_00176 Serine--tRNA ligase [serS]. 3 443 37.117 T 31-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 DFR85_09415 1782a78266cf8e5d5ed6d080fa6410d7 456 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 7 108 8.7E-19 T 31-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 DFR85_09415 1782a78266cf8e5d5ed6d080fa6410d7 456 PRINTS PR00981 Seryl-tRNA synthetase signature 297 310 5.7E-30 T 31-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 DFR85_09415 1782a78266cf8e5d5ed6d080fa6410d7 456 PRINTS PR00981 Seryl-tRNA synthetase signature 372 388 5.7E-30 T 31-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 DFR85_09415 1782a78266cf8e5d5ed6d080fa6410d7 456 PRINTS PR00981 Seryl-tRNA synthetase signature 285 297 5.7E-30 T 31-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 DFR85_09415 1782a78266cf8e5d5ed6d080fa6410d7 456 PRINTS PR00981 Seryl-tRNA synthetase signature 337 350 5.7E-30 T 31-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 DFR85_09415 1782a78266cf8e5d5ed6d080fa6410d7 456 PRINTS PR00981 Seryl-tRNA synthetase signature 354 370 5.7E-30 T 31-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 DFR85_09415 1782a78266cf8e5d5ed6d080fa6410d7 456 Gene3D G3DSA:3.30.930.10 106 447 1.7E-116 T 31-10-2018 DFR85_09415 1782a78266cf8e5d5ed6d080fa6410d7 456 SUPERFAMILY SSF46589 7 113 4.13E-21 T 31-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 DFR85_07400 6b343681b889ac9d7476423d27604921 124 Pfam PF16992 DNA-directed RNA polymerase, subunit G 10 123 2.4E-40 T 31-10-2018 IPR031555 DNA-directed RNA polymerase, subunit G DFR85_07400 6b343681b889ac9d7476423d27604921 124 Gene3D G3DSA:2.40.50.140 1 124 1.5E-39 T 31-10-2018 DFR85_10590 a2b9f649ccbbb162ebf2aa9d5022072e 90 Gene3D G3DSA:3.30.70.100 1 90 8.7E-35 T 31-10-2018 DFR85_10590 a2b9f649ccbbb162ebf2aa9d5022072e 90 SUPERFAMILY SSF54975 2 88 5.01E-27 T 31-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 DFR85_10590 a2b9f649ccbbb162ebf2aa9d5022072e 90 Pfam PF00708 Acylphosphatase 6 88 5.2E-27 T 31-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 DFR85_10590 a2b9f649ccbbb162ebf2aa9d5022072e 90 ProSitePatterns PS00151 Acylphosphatase signature 2. 33 49 - T 31-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 DFR85_10590 a2b9f649ccbbb162ebf2aa9d5022072e 90 ProSitePatterns PS00150 Acylphosphatase signature 1. 9 19 - T 31-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 DFR85_00290 fe3018b7c0393632d3427fe4d23cec39 231 Gene3D G3DSA:3.40.50.1580 4 231 9.1E-50 T 31-10-2018 DFR85_00290 fe3018b7c0393632d3427fe4d23cec39 231 SUPERFAMILY SSF53167 4 230 4.19E-50 T 31-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 DFR85_00290 fe3018b7c0393632d3427fe4d23cec39 231 Pfam PF01048 Phosphorylase superfamily 16 228 3.2E-27 T 31-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 DFR85_11475 4444914a8a2ed18a9c885d339b576e6c 440 Pfam PF02913 FAD linked oxidases, C-terminal domain 204 431 1.5E-46 T 31-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 DFR85_11475 4444914a8a2ed18a9c885d339b576e6c 440 SUPERFAMILY SSF56176 15 200 2.1E-60 T 31-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 DFR85_11475 4444914a8a2ed18a9c885d339b576e6c 440 Gene3D G3DSA:1.10.45.10 389 433 7.4E-8 T 31-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 DFR85_11475 4444914a8a2ed18a9c885d339b576e6c 440 SUPERFAMILY SSF55103 205 433 3.6E-46 T 31-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 DFR85_11475 4444914a8a2ed18a9c885d339b576e6c 440 Pfam PF01565 FAD binding domain 25 162 8.0E-44 T 31-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 DFR85_11475 4444914a8a2ed18a9c885d339b576e6c 440 Gene3D G3DSA:3.30.70.2740 312 388 6.0E-13 T 31-10-2018 DFR85_11475 4444914a8a2ed18a9c885d339b576e6c 440 Gene3D G3DSA:3.30.465.40 5 220 4.7E-68 T 31-10-2018 DFR85_12580 ec4d178e46543f62e90f235f6ab663dd 407 Gene3D G3DSA:3.30.70.360 204 326 3.1E-73 T 31-10-2018 DFR85_12580 ec4d178e46543f62e90f235f6ab663dd 407 Pfam PF07687 Peptidase dimerisation domain 201 308 1.5E-19 T 31-10-2018 IPR011650 Peptidase M20, dimerisation domain DFR85_12580 ec4d178e46543f62e90f235f6ab663dd 407 SUPERFAMILY SSF55031 206 320 2.99E-21 T 31-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain DFR85_12580 ec4d178e46543f62e90f235f6ab663dd 407 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 20 398 8.6E-75 T 31-10-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase DFR85_12580 ec4d178e46543f62e90f235f6ab663dd 407 SUPERFAMILY SSF53187 6 406 1.06E-52 T 31-10-2018 DFR85_12580 ec4d178e46543f62e90f235f6ab663dd 407 Gene3D G3DSA:3.40.630.10 56 393 3.1E-73 T 31-10-2018 DFR85_12580 ec4d178e46543f62e90f235f6ab663dd 407 Pfam PF01546 Peptidase family M20/M25/M40 92 403 3.5E-31 T 31-10-2018 IPR002933 Peptidase M20 GO:0016787 DFR85_01245 7d83e4d2809b234c5bcf8d0d74f6009f 494 Gene3D G3DSA:3.40.50.300 256 475 2.2E-62 T 31-10-2018 DFR85_01245 7d83e4d2809b234c5bcf8d0d74f6009f 494 Pfam PF05872 Bacterial protein of unknown function (DUF853) 353 446 8.5E-5 T 31-10-2018 IPR033186 Helicase HerA-like C-terminal DFR85_01245 7d83e4d2809b234c5bcf8d0d74f6009f 494 SUPERFAMILY SSF52540 102 466 2.14E-40 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_01245 7d83e4d2809b234c5bcf8d0d74f6009f 494 Gene3D G3DSA:3.40.50.300 98 237 9.3E-12 T 31-10-2018 DFR85_01245 7d83e4d2809b234c5bcf8d0d74f6009f 494 Pfam PF09378 HAS barrel domain 3 56 1.0E-6 T 31-10-2018 IPR018538 Helicase HerA, barrel domain DFR85_01245 7d83e4d2809b234c5bcf8d0d74f6009f 494 Pfam PF01935 Domain of unknown function DUF87 118 331 1.8E-41 T 31-10-2018 IPR002789 Helicase HerA, central domain DFR85_06025 6f67da0595f6d19021bbff6f4f5dc296 294 Gene3D G3DSA:3.30.470.80 184 294 7.8E-34 T 31-10-2018 DFR85_06025 6f67da0595f6d19021bbff6f4f5dc296 294 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 2 288 2.8E-61 T 31-10-2018 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 Reactome: R-HSA-70614 DFR85_06025 6f67da0595f6d19021bbff6f4f5dc296 294 SUPERFAMILY SSF56059 94 291 1.18E-44 T 31-10-2018 DFR85_06025 6f67da0595f6d19021bbff6f4f5dc296 294 Gene3D G3DSA:3.40.50.20 3 118 4.1E-10 T 31-10-2018 DFR85_06025 6f67da0595f6d19021bbff6f4f5dc296 294 Pfam PF08443 RimK-like ATP-grasp domain 102 287 3.9E-30 T 31-10-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 DFR85_02350 93fc9f295d713575a8ffbb5c4220273c 135 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 5 103 3.5E-6 T 31-10-2018 IPR007296 Domain of unknown function DUF403 DFR85_14665 1f9c9fccc2cbe0c8b145c46a352ca320 285 Gene3D G3DSA:3.40.50.1220 158 285 5.6E-46 T 31-10-2018 DFR85_14665 1f9c9fccc2cbe0c8b145c46a352ca320 285 PIRSF PIRSF000089 38 285 3.3E-76 T 31-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 DFR85_14665 1f9c9fccc2cbe0c8b145c46a352ca320 285 Gene3D G3DSA:3.40.50.620 1 156 2.6E-16 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR85_14665 1f9c9fccc2cbe0c8b145c46a352ca320 285 SUPERFAMILY SSF52402 53 195 2.51E-19 T 31-10-2018 DFR85_14665 1f9c9fccc2cbe0c8b145c46a352ca320 285 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 163 246 1.1E-29 T 31-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 DFR85_14665 1f9c9fccc2cbe0c8b145c46a352ca320 285 Pfam PF01012 Electron transfer flavoprotein domain 53 139 3.3E-14 T 31-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 DFR85_14665 1f9c9fccc2cbe0c8b145c46a352ca320 285 SUPERFAMILY SSF52467 163 282 7.63E-40 T 31-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily DFR85_03890 de22561b1f5c9b9e74a05398459c707e 519 SUPERFAMILY SSF102114 225 467 2.22E-26 T 31-10-2018 DFR85_03890 de22561b1f5c9b9e74a05398459c707e 519 Pfam PF13394 4Fe-4S single cluster domain 232 322 1.4E-5 T 31-10-2018 DFR85_03890 de22561b1f5c9b9e74a05398459c707e 519 Gene3D G3DSA:3.20.20.70 210 464 3.6E-29 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_03890 de22561b1f5c9b9e74a05398459c707e 519 Pfam PF04055 Radical SAM superfamily 228 376 2.6E-11 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR85_15055 8df6bfe1c833d9e60e7ec495c2b93677 144 Pfam PF00571 CBS domain 81 133 1.0E-12 T 31-10-2018 IPR000644 CBS domain DFR85_15055 8df6bfe1c833d9e60e7ec495c2b93677 144 Pfam PF00571 CBS domain 18 70 3.5E-11 T 31-10-2018 IPR000644 CBS domain DFR85_15055 8df6bfe1c833d9e60e7ec495c2b93677 144 SUPERFAMILY SSF54631 17 132 2.02E-29 T 31-10-2018 DFR85_15055 8df6bfe1c833d9e60e7ec495c2b93677 144 SMART SM00116 86 133 4.5E-7 T 31-10-2018 IPR000644 CBS domain DFR85_15055 8df6bfe1c833d9e60e7ec495c2b93677 144 SMART SM00116 23 70 8.2E-9 T 31-10-2018 IPR000644 CBS domain DFR85_15055 8df6bfe1c833d9e60e7ec495c2b93677 144 Gene3D G3DSA:3.10.580.10 11 135 8.5E-32 T 31-10-2018 DFR85_02470 35dfe5b14cc52a25ec42e99d3a320665 211 SUPERFAMILY SSF52540 3 207 1.48E-26 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_02470 35dfe5b14cc52a25ec42e99d3a320665 211 Pfam PF02223 Thymidylate kinase 9 199 2.0E-12 T 31-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 DFR85_02470 35dfe5b14cc52a25ec42e99d3a320665 211 Gene3D G3DSA:3.40.50.300 2 209 6.1E-30 T 31-10-2018 DFR85_07640 9abcf537dfd7db9243b00400f5c61ef8 466 PIRSF PIRSF038984 2 122 4.5E-9 T 31-10-2018 IPR028348 FAD dependent protein DFR85_07640 9abcf537dfd7db9243b00400f5c61ef8 466 PIRSF PIRSF038984 117 464 2.1E-26 T 31-10-2018 IPR028348 FAD dependent protein DFR85_07640 9abcf537dfd7db9243b00400f5c61ef8 466 Pfam PF01266 FAD dependent oxidoreductase 3 53 3.2E-7 T 31-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 DFR85_07640 9abcf537dfd7db9243b00400f5c61ef8 466 Gene3D G3DSA:3.50.50.60 1 122 1.5E-18 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_07640 9abcf537dfd7db9243b00400f5c61ef8 466 Gene3D G3DSA:3.50.50.60 123 229 4.4E-7 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_07640 9abcf537dfd7db9243b00400f5c61ef8 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 417 439 3.3E-8 T 31-10-2018 DFR85_07640 9abcf537dfd7db9243b00400f5c61ef8 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 3.3E-8 T 31-10-2018 DFR85_07640 9abcf537dfd7db9243b00400f5c61ef8 466 SUPERFAMILY SSF51905 1 459 2.12E-29 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_00045 06e4e75a56923239e0b70e15ec2b6410 185 Pfam PF07185 Protein of unknown function (DUF1404) 15 182 8.6E-55 T 31-10-2018 IPR009844 Protein of unknown function DUF1404 DFR85_03700 c505d8bf297cce7110061e04c0adf800 406 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 291 6.7E-21 T 31-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 DFR85_03700 c505d8bf297cce7110061e04c0adf800 406 Gene3D G3DSA:3.40.50.720 5 299 1.8E-142 T 31-10-2018 DFR85_03700 c505d8bf297cce7110061e04c0adf800 406 SUPERFAMILY SSF51735 4 376 1.99E-46 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_03700 c505d8bf297cce7110061e04c0adf800 406 Gene3D G3DSA:3.90.25.10 211 376 1.8E-142 T 31-10-2018 DFR85_13975 93ce91beb82f3ff8af18ae3f5f091f3e 251 Gene3D G3DSA:3.10.20.10 25 105 7.6E-11 T 31-10-2018 DFR85_13975 93ce91beb82f3ff8af18ae3f5f091f3e 251 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 20 250 3.1E-54 T 31-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 DFR85_13975 93ce91beb82f3ff8af18ae3f5f091f3e 251 Hamap MF_00187 Sulfur carrier protein FdhD [fdhD]. 2 251 30.421 T 31-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 DFR85_13975 93ce91beb82f3ff8af18ae3f5f091f3e 251 Pfam PF02634 FdhD/NarQ family 24 250 9.7E-65 T 31-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 DFR85_13975 93ce91beb82f3ff8af18ae3f5f091f3e 251 Gene3D G3DSA:3.40.140.10 109 251 3.5E-45 T 31-10-2018 DFR85_13975 93ce91beb82f3ff8af18ae3f5f091f3e 251 SUPERFAMILY SSF53927 4 251 1.56E-65 T 31-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 DFR85_13975 93ce91beb82f3ff8af18ae3f5f091f3e 251 PIRSF PIRSF015626 1 251 1.4E-71 T 31-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 DFR85_06020 b556542f9de5c40495acdf5f1ba8f3c0 282 SUPERFAMILY SSF48576 24 207 1.64E-44 T 31-10-2018 IPR008949 Isoprenoid synthase domain superfamily DFR85_06020 b556542f9de5c40495acdf5f1ba8f3c0 282 Pfam PF00348 Polyprenyl synthetase 31 210 2.5E-38 T 31-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 DFR85_06020 b556542f9de5c40495acdf5f1ba8f3c0 282 Gene3D G3DSA:1.10.600.10 1 280 7.4E-72 T 31-10-2018 IPR008949 Isoprenoid synthase domain superfamily DFR85_06020 b556542f9de5c40495acdf5f1ba8f3c0 282 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 192 204 - T 31-10-2018 IPR033749 Polyprenyl synthetase, conserved site DFR85_03825 2f44c241324fe9a3e88005fb47eae8ac 158 Pfam PF01750 Hydrogenase maturation protease 28 126 8.1E-5 T 31-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 DFR85_03825 2f44c241324fe9a3e88005fb47eae8ac 158 SUPERFAMILY SSF53163 1 141 1.31E-20 T 31-10-2018 IPR023430 Peptidase HybD-like domain superfamily DFR85_03825 2f44c241324fe9a3e88005fb47eae8ac 158 Gene3D G3DSA:3.40.50.1450 1 131 3.5E-16 T 31-10-2018 IPR023430 Peptidase HybD-like domain superfamily DFR85_03825 2f44c241324fe9a3e88005fb47eae8ac 158 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 5 127 1.2E-14 T 31-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 DFR85_13270 a76259053e710c9a74e83b7ae00b84f5 554 Pfam PF00136 DNA polymerase family B 258 391 1.4E-11 T 31-10-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DFR85_13270 a76259053e710c9a74e83b7ae00b84f5 554 Gene3D G3DSA:1.10.287.690 315 361 4.0E-44 T 31-10-2018 DFR85_13270 a76259053e710c9a74e83b7ae00b84f5 554 Gene3D G3DSA:3.90.1600.10 264 430 4.0E-44 T 31-10-2018 IPR023211 DNA polymerase, palm domain superfamily KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DFR85_13270 a76259053e710c9a74e83b7ae00b84f5 554 SMART SM00486 25 406 1.0E-10 T 31-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 DFR85_13270 a76259053e710c9a74e83b7ae00b84f5 554 SUPERFAMILY SSF56672 228 513 1.39E-49 T 31-10-2018 DFR85_06940 906d3949dafddf2af7abdab6553302c3 285 Pfam PF01925 Sulfite exporter TauE/SafE 12 277 6.9E-41 T 31-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 DFR85_15365 964221c0b67ccc01663807a6d2a07f59 398 Pfam PF07690 Major Facilitator Superfamily 22 347 1.2E-12 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_15365 964221c0b67ccc01663807a6d2a07f59 398 Gene3D G3DSA:1.20.1250.20 211 392 6.0E-9 T 31-10-2018 DFR85_15365 964221c0b67ccc01663807a6d2a07f59 398 Gene3D G3DSA:1.20.1250.20 3 188 1.7E-5 T 31-10-2018 DFR85_15365 964221c0b67ccc01663807a6d2a07f59 398 SUPERFAMILY SSF103473 17 390 6.28E-22 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_03350 9ae3cc2a450c3b92fa5ae8e122ff6a5f 118 SMART SM00748 5 114 1.3E-33 T 31-10-2018 IPR007842 HEPN domain DFR85_03350 9ae3cc2a450c3b92fa5ae8e122ff6a5f 118 Gene3D G3DSA:1.20.120.330 1 118 2.1E-27 T 31-10-2018 DFR85_03350 9ae3cc2a450c3b92fa5ae8e122ff6a5f 118 Pfam PF05168 HEPN domain 2 117 2.9E-29 T 31-10-2018 IPR007842 HEPN domain DFR85_03350 9ae3cc2a450c3b92fa5ae8e122ff6a5f 118 SUPERFAMILY SSF81593 4 117 5.89E-30 T 31-10-2018 DFR85_05490 c9b0e3a013e749e9e25be6c3c9a56841 543 Gene3D G3DSA:1.20.810.10 1 394 4.7E-78 T 31-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 DFR85_05490 c9b0e3a013e749e9e25be6c3c9a56841 543 SUPERFAMILY SSF81342 19 251 2.83E-44 T 31-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 DFR85_05490 c9b0e3a013e749e9e25be6c3c9a56841 543 Pfam PF13631 Cytochrome b(N-terminal)/b6/petB 87 272 2.0E-56 T 31-10-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 DFR85_05490 c9b0e3a013e749e9e25be6c3c9a56841 543 SUPERFAMILY SSF81648 214 366 5.23E-18 T 31-10-2018 IPR036150 Cytochrome b/b6, C-terminal domain superfamily GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 DFR85_05220 30170095542d3a5466905f7bb38d7eac 244 SUPERFAMILY SSF53448 1 223 1.53E-29 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_05220 30170095542d3a5466905f7bb38d7eac 244 Gene3D G3DSA:3.90.550.10 1 217 2.2E-33 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_05220 30170095542d3a5466905f7bb38d7eac 244 Pfam PF00535 Glycosyl transferase family 2 3 129 8.3E-22 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 DFR85_05425 9d57bcce8fdf1b190a401a3fe9859946 173 Pfam PF06939 Protein of unknown function (DUF1286) 1 108 2.0E-34 T 31-10-2018 IPR009705 Sulfolobus virus STSV1, Orf8 DFR85_04415 4b19e66e65ee80abe613ef0087d5bbea 356 SUPERFAMILY SSF53756 6 356 3.04E-52 T 31-10-2018 DFR85_04415 4b19e66e65ee80abe613ef0087d5bbea 356 Gene3D G3DSA:3.40.50.2000 170 341 3.4E-48 T 31-10-2018 DFR85_04415 4b19e66e65ee80abe613ef0087d5bbea 356 Pfam PF00534 Glycosyl transferases group 1 188 336 8.8E-26 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 DFR85_04415 4b19e66e65ee80abe613ef0087d5bbea 356 Gene3D G3DSA:3.40.50.2000 18 352 3.4E-48 T 31-10-2018 DFR85_04415 4b19e66e65ee80abe613ef0087d5bbea 356 Pfam PF13439 Glycosyltransferase Family 4 18 171 3.7E-7 T 31-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 DFR85_06445 28d7f80f653086f3129a4b4a4e07d6fb 131 Gene3D G3DSA:3.10.580.10 1 128 2.3E-42 T 31-10-2018 DFR85_06445 28d7f80f653086f3129a4b4a4e07d6fb 131 SMART SM00116 75 123 4.1E-12 T 31-10-2018 IPR000644 CBS domain DFR85_06445 28d7f80f653086f3129a4b4a4e07d6fb 131 SMART SM00116 12 59 6.1E-9 T 31-10-2018 IPR000644 CBS domain DFR85_06445 28d7f80f653086f3129a4b4a4e07d6fb 131 SUPERFAMILY SSF54631 4 125 3.79E-37 T 31-10-2018 DFR85_06445 28d7f80f653086f3129a4b4a4e07d6fb 131 Pfam PF00571 CBS domain 5 58 1.6E-14 T 31-10-2018 IPR000644 CBS domain DFR85_06445 28d7f80f653086f3129a4b4a4e07d6fb 131 Pfam PF00571 CBS domain 69 123 1.4E-14 T 31-10-2018 IPR000644 CBS domain DFR85_08440 2008e22eef8163b29302930f3310f8fb 291 Pfam PF01925 Sulfite exporter TauE/SafE 15 273 1.6E-48 T 31-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 DFR85_02970 8843ae8d3e0a6fe511607d0e4cb573b0 410 Pfam PF01979 Amidohydrolase family 51 401 3.1E-54 T 31-10-2018 IPR006680 Amidohydrolase-related GO:0016787 DFR85_02970 8843ae8d3e0a6fe511607d0e4cb573b0 410 SUPERFAMILY SSF51556 55 359 1.63E-80 T 31-10-2018 IPR032466 Metal-dependent hydrolase DFR85_02970 8843ae8d3e0a6fe511607d0e4cb573b0 410 SUPERFAMILY SSF51338 1 402 2.29E-16 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR85_02970 8843ae8d3e0a6fe511607d0e4cb573b0 410 Gene3D G3DSA:3.20.20.140 57 364 1.0E-114 T 31-10-2018 DFR85_02970 8843ae8d3e0a6fe511607d0e4cb573b0 410 Gene3D G3DSA:2.30.40.10 18 401 1.0E-114 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR85_07175 503c10d2d5fc08d88b55c37b8c7ac29c 244 Pfam PF01138 3' exoribonuclease family, domain 1 24 153 3.6E-35 T 31-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 DFR85_07175 503c10d2d5fc08d88b55c37b8c7ac29c 244 SUPERFAMILY SSF55666 153 240 7.07E-24 T 31-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 DFR85_07175 503c10d2d5fc08d88b55c37b8c7ac29c 244 TIGRFAM TIGR02065 ECX1: exosome complex exonuclease 1 8 237 1.4E-117 T 31-10-2018 IPR011807 Exosome complex component Rrp41 GO:0000178|GO:0006401|GO:0016896 DFR85_07175 503c10d2d5fc08d88b55c37b8c7ac29c 244 SUPERFAMILY SSF54211 9 164 7.59E-45 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold DFR85_07175 503c10d2d5fc08d88b55c37b8c7ac29c 244 Gene3D G3DSA:3.30.230.70 3 242 2.8E-72 T 31-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 DFR85_07175 503c10d2d5fc08d88b55c37b8c7ac29c 244 Hamap MF_00591 Exosome complex component Rrp41 [rrp41]. 5 241 58.455 T 31-10-2018 IPR011807 Exosome complex component Rrp41 GO:0000178|GO:0006401|GO:0016896 DFR85_07175 503c10d2d5fc08d88b55c37b8c7ac29c 244 Pfam PF03725 3' exoribonuclease family, domain 2 156 221 4.0E-12 T 31-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 DFR85_00555 10c2d274e39f65acc7c9f6eede810715 446 Pfam PF05167 Uncharacterised ACR (DUF711) 14 408 1.4E-121 T 31-10-2018 IPR007841 Uncharacterised protein family UPF0210 DFR85_00555 10c2d274e39f65acc7c9f6eede810715 446 Gene3D G3DSA:3.20.70.20 2 445 2.7E-130 T 31-10-2018 DFR85_00555 10c2d274e39f65acc7c9f6eede810715 446 SUPERFAMILY SSF51998 4 439 3.11E-125 T 31-10-2018 DFR85_12275 cb12b0ec815251af5b4b751d54edd9a7 880 SUPERFAMILY SSF52540 379 624 1.82E-58 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_12275 cb12b0ec815251af5b4b751d54edd9a7 880 Gene3D G3DSA:3.40.50.10810 415 625 8.4E-82 T 31-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily DFR85_12275 cb12b0ec815251af5b4b751d54edd9a7 880 Pfam PF00176 SNF2 family N-terminal domain 434 694 3.1E-61 T 31-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 DFR85_12275 cb12b0ec815251af5b4b751d54edd9a7 880 Pfam PF12419 SNF2 Helicase protein 262 381 3.0E-15 T 31-10-2018 IPR022138 Helicase SWF/SNF-related DFR85_12275 cb12b0ec815251af5b4b751d54edd9a7 880 SMART SM00490 736 820 1.8E-19 T 31-10-2018 IPR001650 Helicase, C-terminal DFR85_12275 cb12b0ec815251af5b4b751d54edd9a7 880 Gene3D G3DSA:3.40.50.300 633 834 4.5E-91 T 31-10-2018 DFR85_12275 cb12b0ec815251af5b4b751d54edd9a7 880 Gene3D G3DSA:1.20.120.850 648 870 4.5E-91 T 31-10-2018 DFR85_12275 cb12b0ec815251af5b4b751d54edd9a7 880 SUPERFAMILY SSF52540 530 876 5.32E-59 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_12275 cb12b0ec815251af5b4b751d54edd9a7 880 SMART SM00487 410 598 4.9E-32 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain DFR85_12275 cb12b0ec815251af5b4b751d54edd9a7 880 Pfam PF00271 Helicase conserved C-terminal domain 715 820 5.4E-16 T 31-10-2018 IPR001650 Helicase, C-terminal DFR85_13045 e978b768656c6b1922b0bdb0c996d302 184 Gene3D G3DSA:3.10.590.10 15 127 1.9E-5 T 31-10-2018 DFR85_07125 c0d55a225ae2c14ccbc3d2b3312b32d2 197 Gene3D G3DSA:1.20.58.290 124 185 1.9E-5 T 31-10-2018 DFR85_07125 c0d55a225ae2c14ccbc3d2b3312b32d2 197 Pfam PF04289 Protein of unknown function (DUF447) 16 180 1.1E-32 T 31-10-2018 IPR007386 Protein of unknown function DUF447 DFR85_07125 c0d55a225ae2c14ccbc3d2b3312b32d2 197 Gene3D G3DSA:2.30.110.10 6 123 6.3E-19 T 31-10-2018 IPR012349 FMN-binding split barrel GO:0048037 DFR85_07125 c0d55a225ae2c14ccbc3d2b3312b32d2 197 SUPERFAMILY SSF50475 9 177 3.14E-28 T 31-10-2018 DFR85_09510 12eab5f4cda81407b2d5e105a7cc6b89 284 Hamap MF_01286 Digeranylgeranylglyceryl phosphate synthase. 1 274 21.242 T 31-10-2018 IPR023547 Digeranylgeranylglyceryl phosphate synthase GO:0000287|GO:0005886|GO:0008654|GO:0047295 KEGG: 00564+2.5.1.42|MetaCyc: PWY-6349 DFR85_09510 12eab5f4cda81407b2d5e105a7cc6b89 284 Pfam PF01040 UbiA prenyltransferase family 21 255 3.3E-42 T 31-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 DFR85_09510 12eab5f4cda81407b2d5e105a7cc6b89 284 Gene3D G3DSA:1.10.357.140 7 160 1.8E-16 T 31-10-2018 DFR85_13295 e52e57acdb4fa2d1bdae587f09d895ef 426 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 370 406 1.5E-5 T 31-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain DFR85_13295 e52e57acdb4fa2d1bdae587f09d895ef 426 Gene3D G3DSA:3.40.50.10710 218 377 6.4E-58 T 31-10-2018 DFR85_13295 e52e57acdb4fa2d1bdae587f09d895ef 426 SMART SM00849 20 211 1.6E-4 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR85_13295 e52e57acdb4fa2d1bdae587f09d895ef 426 SUPERFAMILY SSF56281 10 423 6.36E-26 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR85_13295 e52e57acdb4fa2d1bdae587f09d895ef 426 Gene3D G3DSA:3.60.15.10 8 404 6.4E-58 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR85_10195 19b75234eaff440f4858c1d5e440bf2d 207 ProDom PD019177 PF1672 MJ0935 ST1363 PH1730 UNCHARACTERIZED ARCHAEAL 10 60 3.0E-13 T 31-10-2018 IPR007368 Protein of unknown function DUF434 DFR85_10195 19b75234eaff440f4858c1d5e440bf2d 207 Pfam PF04256 Protein of unknown function (DUF434) 7 61 4.5E-22 T 31-10-2018 IPR007368 Protein of unknown function DUF434 DFR85_00635 355738a84e66d9cce3aa805f9985ffba 209 Gene3D G3DSA:3.30.420.10 3 155 9.8E-41 T 31-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 DFR85_00635 355738a84e66d9cce3aa805f9985ffba 209 TIGRFAM TIGR00729 TIGR00729: ribonuclease HII 3 198 3.8E-60 T 31-10-2018 IPR004649 Ribonuclease H2, subunit A GO:0004523|GO:0016070 DFR85_00635 355738a84e66d9cce3aa805f9985ffba 209 Hamap MF_00052_A Ribonuclease HII [rnhB]. 1 200 30.203 T 31-10-2018 IPR020787 Ribonuclease HII, archaea GO:0004523|GO:0005737|GO:0006401|GO:0030145 DFR85_00635 355738a84e66d9cce3aa805f9985ffba 209 Pfam PF01351 Ribonuclease HII 3 193 2.0E-47 T 31-10-2018 IPR024567 Ribonuclease HII/HIII domain DFR85_00635 355738a84e66d9cce3aa805f9985ffba 209 Gene3D G3DSA:1.10.10.460 156 201 1.3E-19 T 31-10-2018 IPR023160 Ribonuclease HII, helix-loop-helix cap domain superfamily GO:0004523 DFR85_00635 355738a84e66d9cce3aa805f9985ffba 209 SUPERFAMILY SSF53098 2 198 2.58E-52 T 31-10-2018 IPR012337 Ribonuclease H-like superfamily DFR85_13575 1af9e8841193a17e460c8b880192c926 687 Gene3D G3DSA:3.30.365.10 167 257 6.1E-43 T 31-10-2018 DFR85_13575 1af9e8841193a17e460c8b880192c926 687 SUPERFAMILY SSF56003 109 684 8.9E-126 T 31-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 DFR85_13575 1af9e8841193a17e460c8b880192c926 687 SMART SM01008 11 117 1.1E-27 T 31-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DFR85_13575 1af9e8841193a17e460c8b880192c926 687 Gene3D G3DSA:3.30.365.10 413 547 3.1E-71 T 31-10-2018 DFR85_13575 1af9e8841193a17e460c8b880192c926 687 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 12 116 3.5E-19 T 31-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DFR85_13575 1af9e8841193a17e460c8b880192c926 687 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 156 630 1.9E-94 T 31-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DFR85_13575 1af9e8841193a17e460c8b880192c926 687 SUPERFAMILY SSF54665 2 135 9.94E-29 T 31-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily DFR85_13575 1af9e8841193a17e460c8b880192c926 687 Gene3D G3DSA:3.90.1170.50 1 117 2.5E-27 T 31-10-2018 DFR85_13575 1af9e8841193a17e460c8b880192c926 687 Gene3D G3DSA:3.30.365.10 131 331 6.1E-43 T 31-10-2018 DFR85_13575 1af9e8841193a17e460c8b880192c926 687 Gene3D G3DSA:3.30.365.10 343 683 3.1E-71 T 31-10-2018 DFR85_02820 90deda5fbdcb843405cdd6aaf74fd434 174 Pfam PF00866 Ring hydroxylating beta subunit 32 149 1.0E-15 T 31-10-2018 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0006725|GO:0055114 DFR85_02820 90deda5fbdcb843405cdd6aaf74fd434 174 SUPERFAMILY SSF54427 21 172 3.63E-15 T 31-10-2018 IPR032710 NTF2-like domain superfamily DFR85_02820 90deda5fbdcb843405cdd6aaf74fd434 174 Gene3D G3DSA:3.10.450.50 3 174 3.6E-27 T 31-10-2018 DFR85_09135 bb6423a399ac2a0f27336b846165890b 411 SUPERFAMILY SSF111283 2 410 1.7E-52 T 31-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 DFR85_09135 bb6423a399ac2a0f27336b846165890b 411 Pfam PF01523 Putative modulator of DNA gyrase 16 287 2.7E-30 T 31-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 DFR85_09135 bb6423a399ac2a0f27336b846165890b 411 Gene3D G3DSA:3.30.2290.10 1 189 4.9E-18 T 31-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal DFR85_07765 eed433b932d3b156787f20e4571bf348 146 Gene3D G3DSA:2.40.50.140 27 146 2.2E-50 T 31-10-2018 DFR85_07765 eed433b932d3b156787f20e4571bf348 146 TIGRFAM TIGR00982 uS12_E_A: ribosomal protein uS12 8 146 2.0E-75 T 31-10-2018 IPR005680 Ribosomal protein S23, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07765 eed433b932d3b156787f20e4571bf348 146 SUPERFAMILY SSF50249 22 144 6.6E-35 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR85_07765 eed433b932d3b156787f20e4571bf348 146 Hamap MF_00403_A 30S ribosomal protein S12 [rpsL]. 1 146 42.081 T 31-10-2018 IPR022863 Ribosomal protein S12, archaea DFR85_07765 eed433b932d3b156787f20e4571bf348 146 PIRSF PIRSF002133 18 146 1.3E-33 T 31-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_07765 eed433b932d3b156787f20e4571bf348 146 ProSitePatterns PS00055 Ribosomal protein S12 signature. 62 69 - T 31-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_07765 eed433b932d3b156787f20e4571bf348 146 Pfam PF00164 Ribosomal protein S12/S23 33 144 9.5E-48 T 31-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_01830 aac027ba294f8393c8aca7344aa2af6f 315 Gene3D G3DSA:3.90.650.10 134 306 3.8E-31 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily DFR85_01830 aac027ba294f8393c8aca7344aa2af6f 315 SUPERFAMILY SSF55326 12 128 2.44E-17 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily DFR85_01830 aac027ba294f8393c8aca7344aa2af6f 315 Pfam PF02769 AIR synthase related protein, C-terminal domain 139 283 4.5E-16 T 31-10-2018 IPR010918 PurM-like, C-terminal domain DFR85_01830 aac027ba294f8393c8aca7344aa2af6f 315 PIRSF PIRSF005644 1 306 9.8E-71 T 31-10-2018 IPR011854 Carbamoyl dehydratase HypE DFR85_01830 aac027ba294f8393c8aca7344aa2af6f 315 Gene3D G3DSA:3.30.1330.10 8 133 2.9E-18 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily DFR85_01830 aac027ba294f8393c8aca7344aa2af6f 315 SUPERFAMILY SSF56042 136 287 6.28E-25 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily DFR85_01830 aac027ba294f8393c8aca7344aa2af6f 315 Pfam PF00586 AIR synthase related protein, N-terminal domain 30 128 6.8E-11 T 31-10-2018 IPR016188 PurM-like, N-terminal domain DFR85_12790 0e69b08c7df99e7aaada53edd18df0a9 340 SUPERFAMILY SSF55681 10 245 4.1E-56 T 31-10-2018 DFR85_12790 0e69b08c7df99e7aaada53edd18df0a9 340 Gene3D G3DSA:3.30.930.10 11 250 2.3E-50 T 31-10-2018 DFR85_12790 0e69b08c7df99e7aaada53edd18df0a9 340 SUPERFAMILY SSF82649 259 335 2.88E-12 T 31-10-2018 DFR85_12790 0e69b08c7df99e7aaada53edd18df0a9 340 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 259 335 1.8E-6 T 31-10-2018 IPR019491 Lipoate protein ligase, C-terminal KEGG: 00785+6.3.1.20 DFR85_12790 0e69b08c7df99e7aaada53edd18df0a9 340 Pfam PF03099 Biotin/lipoate A/B protein ligase family 53 160 8.8E-6 T 31-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 DFR85_12790 0e69b08c7df99e7aaada53edd18df0a9 340 Gene3D G3DSA:3.30.390.50 253 336 4.9E-24 T 31-10-2018 DFR85_02025 65c4e73870e4c67464240eafd49109a8 453 ProSitePatterns PS00217 Sugar transport proteins signature 2. 105 130 - T 31-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DFR85_02025 65c4e73870e4c67464240eafd49109a8 453 SUPERFAMILY SSF103473 4 441 7.32E-57 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_02025 65c4e73870e4c67464240eafd49109a8 453 Pfam PF00083 Sugar (and other) transporter 41 441 2.2E-42 T 31-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 DFR85_07835 2f576729a6232bb1553720487c5af46e 96 SUPERFAMILY SSF50104 1 91 1.29E-24 T 31-10-2018 IPR008991 Translation protein SH3-like domain superfamily DFR85_07835 2f576729a6232bb1553720487c5af46e 96 Gene3D G3DSA:2.30.30.30 2 87 1.7E-36 T 31-10-2018 IPR014722 Ribosomal protein L2, domain 2 DFR85_07835 2f576729a6232bb1553720487c5af46e 96 Hamap MF_00721 50S ribosomal protein L14e [rpl14e]. 1 80 29.335 T 31-10-2018 IPR023651 Ribosomal protein L14e GO:0003735|GO:0005840|GO:0006412 DFR85_00865 c553ddbbefd969c1b0b6768d806eeb5e 49 Pfam PF04945 YHS domain 1 44 2.6E-15 T 31-10-2018 IPR007029 YHS domain DFR85_00865 c553ddbbefd969c1b0b6768d806eeb5e 49 SUPERFAMILY SSF47240 4 43 9.46E-7 T 31-10-2018 IPR009078 Ferritin-like superfamily DFR85_00865 c553ddbbefd969c1b0b6768d806eeb5e 49 SMART SM00746 3 39 2.3E-6 T 31-10-2018 IPR011017 TRASH domain DFR85_00865 c553ddbbefd969c1b0b6768d806eeb5e 49 Gene3D G3DSA:1.10.620.20 1 49 1.9E-8 T 31-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 DFR85_08285 23f72e2efd46d0c425c2191c4743880e 187 ProSitePatterns PS01331 Thymidylate kinase signature. 80 92 - T 31-10-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 DFR85_08285 23f72e2efd46d0c425c2191c4743880e 187 Gene3D G3DSA:3.40.50.300 2 187 1.4E-49 T 31-10-2018 DFR85_08285 23f72e2efd46d0c425c2191c4743880e 187 Pfam PF02223 Thymidylate kinase 6 176 3.0E-40 T 31-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 DFR85_08285 23f72e2efd46d0c425c2191c4743880e 187 Hamap MF_00165 Thymidylate kinase [tmk]. 2 184 21.192 T 31-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 DFR85_08285 23f72e2efd46d0c425c2191c4743880e 187 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 2 176 1.0E-41 T 31-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 DFR85_08285 23f72e2efd46d0c425c2191c4743880e 187 SUPERFAMILY SSF52540 1 185 9.97E-41 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_05675 6e751b8345738e4991944b773d8ecaa3 571 SUPERFAMILY SSF48208 179 567 2.48E-79 T 31-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 DFR85_05675 6e751b8345738e4991944b773d8ecaa3 571 Pfam PF00723 Glycosyl hydrolases family 15 206 515 4.3E-41 T 31-10-2018 IPR011613 GH15-like domain Reactome: R-HSA-70221 DFR85_05675 6e751b8345738e4991944b773d8ecaa3 571 Gene3D G3DSA:1.50.10.10 205 570 1.1E-67 T 31-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 DFR85_15610 c16dfc61206aea01ad2bccf7d4e2d93c 114 SUPERFAMILY SSF46785 13 100 2.77E-12 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_15610 c16dfc61206aea01ad2bccf7d4e2d93c 114 Gene3D G3DSA:1.10.10.10 5 113 2.2E-33 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_15610 c16dfc61206aea01ad2bccf7d4e2d93c 114 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 21 88 6.1E-9 T 31-10-2018 IPR002831 Transcription regulator TrmB, N-terminal DFR85_07240 570112813ce3fcc45f500127f0377313 218 Pfam PF00398 Ribosomal RNA adenine dimethylase 3 161 1.5E-8 T 31-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm DFR85_07240 570112813ce3fcc45f500127f0377313 218 Gene3D G3DSA:3.40.50.150 6 160 1.1E-23 T 31-10-2018 DFR85_07240 570112813ce3fcc45f500127f0377313 218 SUPERFAMILY SSF53335 6 187 8.74E-22 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR85_07240 570112813ce3fcc45f500127f0377313 218 SMART SM00650 14 160 1.9E-14 T 31-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 DFR85_07240 570112813ce3fcc45f500127f0377313 218 Gene3D G3DSA:1.10.8.100 115 191 1.1E-23 T 31-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 DFR85_05400 ac863e38f6b5255247acd79dbc72ac66 186 Pfam PF07185 Protein of unknown function (DUF1404) 14 181 4.0E-60 T 31-10-2018 IPR009844 Protein of unknown function DUF1404 DFR85_15430 56a1fbce19bb7ca2792fb20db992666f 309 SUPERFAMILY SSF54593 1 259 1.2E-43 T 31-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DFR85_15430 56a1fbce19bb7ca2792fb20db992666f 309 TIGRFAM TIGR02295 HpaD: 3,4-dihydroxyphenylacetate 2,3-dioxygenase 2 295 2.8E-108 T 31-10-2018 IPR011981 3,4-dihydroxyphenylacetate 2,3-dioxygenase, Mn/Fe-type DFR85_15430 56a1fbce19bb7ca2792fb20db992666f 309 Gene3D G3DSA:3.10.180.10 1 133 3.2E-34 T 31-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DFR85_15430 56a1fbce19bb7ca2792fb20db992666f 309 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 134 252 5.3E-13 T 31-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain DFR85_15430 56a1fbce19bb7ca2792fb20db992666f 309 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 106 2.4E-9 T 31-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain DFR85_15430 56a1fbce19bb7ca2792fb20db992666f 309 ProSitePatterns PS00934 Glyoxalase I signature 1. 8 29 - T 31-10-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 DFR85_15430 56a1fbce19bb7ca2792fb20db992666f 309 Gene3D G3DSA:3.10.180.10 134 295 1.6E-36 T 31-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase DFR85_14085 b8d6490ad4d02baae1f106ad5604114c 76 SUPERFAMILY SSF159127 10 68 4.97E-13 T 31-10-2018 IPR037254 HupF/HypC superfamily DFR85_14085 b8d6490ad4d02baae1f106ad5604114c 76 Pfam PF01455 HupF/HypC family 10 68 2.2E-17 T 31-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC DFR85_14085 b8d6490ad4d02baae1f106ad5604114c 76 Gene3D G3DSA:2.40.50.970 9 76 5.2E-18 T 31-10-2018 IPR037254 HupF/HypC superfamily DFR85_14085 b8d6490ad4d02baae1f106ad5604114c 76 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 13 69 1.6E-14 T 31-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC DFR85_14045 abe4c3ac2ce34776285ef51217c2b0a4 301 SUPERFAMILY SSF57997 15 175 1.67E-11 T 31-10-2018 DFR85_14045 abe4c3ac2ce34776285ef51217c2b0a4 301 Gene3D G3DSA:1.10.601.10 1 193 2.5E-7 T 31-10-2018 DFR85_05250 d94b478b04c5c6764208473ff5ad87cb 386 Gene3D G3DSA:1.20.1250.20 5 197 1.3E-14 T 31-10-2018 DFR85_05250 d94b478b04c5c6764208473ff5ad87cb 386 Gene3D G3DSA:1.20.1250.20 209 383 1.1E-14 T 31-10-2018 DFR85_05250 d94b478b04c5c6764208473ff5ad87cb 386 Pfam PF07690 Major Facilitator Superfamily 18 258 3.5E-17 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_05250 d94b478b04c5c6764208473ff5ad87cb 386 SUPERFAMILY SSF103473 12 378 4.97E-36 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_01250 26f082af6a8bc7eddf084d3c688799d8 380 Gene3D G3DSA:3.60.21.10 1 251 6.4E-57 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like DFR85_01250 26f082af6a8bc7eddf084d3c688799d8 380 SUPERFAMILY SSF56300 1 296 2.89E-52 T 31-10-2018 DFR85_01250 26f082af6a8bc7eddf084d3c688799d8 380 Hamap MF_02044 DNA double-strand break repair protein Mre11 [mre11]. 1 374 24.492 T 31-10-2018 IPR032885 DNA double-strand break repair protein Mre11, archaea-type GO:0006302 DFR85_01250 26f082af6a8bc7eddf084d3c688799d8 380 Pfam PF00149 Calcineurin-like phosphoesterase 1 196 1.0E-12 T 31-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 DFR85_13125 32780b106f4ffcabbd3951213cd2b13d 85 Pfam PF09827 CRISPR associated protein Cas2 1 67 2.6E-20 T 31-10-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 DFR85_13125 32780b106f4ffcabbd3951213cd2b13d 85 Gene3D G3DSA:3.30.70.240 1 65 1.6E-27 T 31-10-2018 DFR85_13125 32780b106f4ffcabbd3951213cd2b13d 85 SUPERFAMILY SSF143430 1 79 7.59E-24 T 31-10-2018 DFR85_13125 32780b106f4ffcabbd3951213cd2b13d 85 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 85 13.649 T 31-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 DFR85_13125 32780b106f4ffcabbd3951213cd2b13d 85 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 1 80 4.1E-14 T 31-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 DFR85_15105 eeb70a0e43bba6fefbc88e2919184993 126 Pfam PF05942 Archaeal PaREP1/PaREP8 family 6 110 1.0E-20 T 31-10-2018 IPR010268 Archaeal PaREP1 DFR85_15105 eeb70a0e43bba6fefbc88e2919184993 126 Gene3D G3DSA:1.20.120.330 2 123 7.8E-31 T 31-10-2018 DFR85_10875 98cca88084d0ad14fb68b370e451eea5 98 Pfam PF01918 Alba 10 72 1.9E-22 T 31-10-2018 IPR002775 DNA/RNA-binding protein Alba-like GO:0003676 DFR85_10875 98cca88084d0ad14fb68b370e451eea5 98 ProDom PD010497 ALBA DNA-BINDING DNA/RNA-BINDING RNA-BINDING ACETYLATION 3D-STRUCTURE DNA CONDENSATION AF1 SSO10B 13 97 2.0E-38 T 31-10-2018 DFR85_10875 98cca88084d0ad14fb68b370e451eea5 98 Gene3D G3DSA:3.30.110.20 1 97 1.7E-34 T 31-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 DFR85_10875 98cca88084d0ad14fb68b370e451eea5 98 Hamap MF_01122 DNA/RNA-binding protein Alba [albA]. 1 96 27.713 T 31-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 DFR85_10875 98cca88084d0ad14fb68b370e451eea5 98 TIGRFAM TIGR00285 TIGR00285: DNA-binding protein Alba 10 96 7.3E-36 T 31-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 DFR85_10875 98cca88084d0ad14fb68b370e451eea5 98 PIRSF PIRSF028732 6 97 3.9E-36 T 31-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 DFR85_10875 98cca88084d0ad14fb68b370e451eea5 98 SUPERFAMILY SSF82704 10 96 1.44E-27 T 31-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 DFR85_15765 12c7577d7a3f4d1c94839a07678def9a 593 PRINTS PR01165 Cytochrome c oxidase subunit I signature 114 138 1.5E-11 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_15765 12c7577d7a3f4d1c94839a07678def9a 593 PRINTS PR01165 Cytochrome c oxidase subunit I signature 253 274 1.5E-11 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_15765 12c7577d7a3f4d1c94839a07678def9a 593 PRINTS PR01165 Cytochrome c oxidase subunit I signature 299 314 1.5E-11 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_15765 12c7577d7a3f4d1c94839a07678def9a 593 PRINTS PR01165 Cytochrome c oxidase subunit I signature 389 408 1.5E-11 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_15765 12c7577d7a3f4d1c94839a07678def9a 593 PRINTS PR01165 Cytochrome c oxidase subunit I signature 87 110 1.5E-11 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_15765 12c7577d7a3f4d1c94839a07678def9a 593 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 48 482 1.3E-72 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_15765 12c7577d7a3f4d1c94839a07678def9a 593 SUPERFAMILY SSF81442 36 515 1.7E-78 T 31-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_15765 12c7577d7a3f4d1c94839a07678def9a 593 Gene3D G3DSA:1.20.210.10 22 524 1.9E-82 T 31-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_08900 ed45747acbfc612b0b113c647f8d2eb1 153 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 6 136 16.849 T 31-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 DFR85_08900 ed45747acbfc612b0b113c647f8d2eb1 153 PIRSF PIRSF002181 1 148 1.9E-33 T 31-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 DFR85_08900 ed45747acbfc612b0b113c647f8d2eb1 153 TIGRFAM TIGR01077 L13_A_E: ribosomal protein uL13 7 145 1.7E-38 T 31-10-2018 IPR005755 Ribosomal protein L13, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 DFR85_08900 ed45747acbfc612b0b113c647f8d2eb1 153 Pfam PF00572 Ribosomal protein L13 7 107 1.5E-6 T 31-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 DFR85_08900 ed45747acbfc612b0b113c647f8d2eb1 153 Gene3D G3DSA:3.90.1180.10 1 146 1.8E-41 T 31-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 DFR85_08900 ed45747acbfc612b0b113c647f8d2eb1 153 SUPERFAMILY SSF52161 3 146 1.4E-34 T 31-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 DFR85_04660 2820d74e02e074dd7d67eb8f1dea8ac1 128 Gene3D G3DSA:3.40.630.30 2 127 4.6E-18 T 31-10-2018 DFR85_04660 2820d74e02e074dd7d67eb8f1dea8ac1 128 SUPERFAMILY SSF55729 1 118 6.38E-15 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase DFR85_04660 2820d74e02e074dd7d67eb8f1dea8ac1 128 Pfam PF00583 Acetyltransferase (GNAT) family 52 126 1.8E-10 T 31-10-2018 IPR000182 GNAT domain DFR85_15110 082605e8260edd242dac604dc4448738 117 Pfam PF05942 Archaeal PaREP1/PaREP8 family 5 114 1.9E-28 T 31-10-2018 IPR010268 Archaeal PaREP1 DFR85_15110 082605e8260edd242dac604dc4448738 117 Gene3D G3DSA:1.20.120.330 2 117 7.8E-40 T 31-10-2018 DFR85_12245 5169d178cd34e7c7515928c5cbbb55d5 130 Pfam PF01883 Iron-sulfur cluster assembly protein 12 85 6.8E-19 T 31-10-2018 IPR002744 MIP18 family-like DFR85_12245 5169d178cd34e7c7515928c5cbbb55d5 130 SUPERFAMILY SSF117916 10 104 2.78E-25 T 31-10-2018 IPR034904 Fe-S cluster assembly domain superfamily DFR85_12245 5169d178cd34e7c7515928c5cbbb55d5 130 Gene3D G3DSA:3.30.300.130 3 106 2.8E-28 T 31-10-2018 IPR034904 Fe-S cluster assembly domain superfamily DFR85_11175 3d35ed3bd1116ed79567d802c0c008c8 328 SUPERFAMILY SSF56747 5 323 4.8E-88 T 31-10-2018 DFR85_11175 3d35ed3bd1116ed79567d802c0c008c8 328 Pfam PF01896 DNA primase small subunit 138 201 2.9E-6 T 31-10-2018 IPR002755 DNA primase, small subunit GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 DFR85_11175 3d35ed3bd1116ed79567d802c0c008c8 328 Hamap MF_00700 DNA primase small subunit PriS [priS]. 12 319 26.551 T 31-10-2018 IPR023639 DNA primase small subunit PriS GO:0003896 DFR85_11175 3d35ed3bd1116ed79567d802c0c008c8 328 Gene3D G3DSA:3.90.920.30 1 328 1.9E-116 T 31-10-2018 DFR85_10410 9f8f21aef57a947bd212bafa8aca3e95 246 Pfam PF00005 ABC transporter 19 171 3.9E-23 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR85_10410 9f8f21aef57a947bd212bafa8aca3e95 246 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 4 242 3.3E-91 T 31-10-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 DFR85_10410 9f8f21aef57a947bd212bafa8aca3e95 246 SMART SM00382 28 222 5.0E-4 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_10410 9f8f21aef57a947bd212bafa8aca3e95 246 SUPERFAMILY SSF52540 4 229 1.24E-45 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_10410 9f8f21aef57a947bd212bafa8aca3e95 246 Gene3D G3DSA:3.40.50.300 1 243 2.2E-57 T 31-10-2018 DFR85_10220 54fc40f2559f2ff4dc564f2acbb18432 133 Gene3D G3DSA:1.10.12.20 12 49 1.5E-5 T 31-10-2018 DFR85_10220 54fc40f2559f2ff4dc564f2acbb18432 133 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 16 43 2.2E-7 T 31-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal DFR85_10220 54fc40f2559f2ff4dc564f2acbb18432 133 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 49 109 7.2E-14 T 31-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal DFR85_10220 54fc40f2559f2ff4dc564f2acbb18432 133 SUPERFAMILY SSF50249 9 114 5.14E-24 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR85_15170 98102cb71db5a621a2531bb0e6d8af2c 433 Gene3D G3DSA:1.20.1250.20 4 426 1.3E-45 T 31-10-2018 DFR85_15170 98102cb71db5a621a2531bb0e6d8af2c 433 Pfam PF07690 Major Facilitator Superfamily 23 362 2.1E-28 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_15170 98102cb71db5a621a2531bb0e6d8af2c 433 ProSitePatterns PS00217 Sugar transport proteins signature 2. 107 132 - T 31-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DFR85_15170 98102cb71db5a621a2531bb0e6d8af2c 433 SUPERFAMILY SSF103473 7 419 1.18E-53 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_05760 d3522be49c89f85b20a8bd658b60d923 220 Pfam PF00005 ABC transporter 16 138 2.4E-15 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR85_05760 d3522be49c89f85b20a8bd658b60d923 220 Gene3D G3DSA:3.40.50.300 1 211 3.3E-44 T 31-10-2018 DFR85_05760 d3522be49c89f85b20a8bd658b60d923 220 SUPERFAMILY SSF52540 7 196 1.66E-45 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_05760 d3522be49c89f85b20a8bd658b60d923 220 SMART SM00382 24 191 3.8E-11 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_07390 f17c5b2c29f3c96a3eed1ed6c7c09965 495 Hamap MF_01634 tRNA-guanine(15) transglycosylase [tgtA]. 4 492 41.424 T 31-10-2018 IPR004804 tRNA-guanine(15) transglycosylase GO:0006400|GO:0016763 MetaCyc: PWY-6711|MetaCyc: PWY-7923 DFR85_07390 f17c5b2c29f3c96a3eed1ed6c7c09965 495 SUPERFAMILY SSF51713 3 353 3.4E-97 T 31-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 DFR85_07390 f17c5b2c29f3c96a3eed1ed6c7c09965 495 SUPERFAMILY SSF88802 362 456 2.48E-10 T 31-10-2018 DFR85_07390 f17c5b2c29f3c96a3eed1ed6c7c09965 495 Pfam PF01702 Queuine tRNA-ribosyltransferase 103 327 1.4E-33 T 31-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 DFR85_07390 f17c5b2c29f3c96a3eed1ed6c7c09965 495 Gene3D G3DSA:3.20.20.105 1 353 1.0E-94 T 31-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 DFR85_07390 f17c5b2c29f3c96a3eed1ed6c7c09965 495 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 4 332 1.2E-63 T 31-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 DFR85_07390 f17c5b2c29f3c96a3eed1ed6c7c09965 495 TIGRFAM TIGR00432 arcsn_tRNA_tgt: tRNA-guanine(15) transglycosylase 4 456 6.0E-121 T 31-10-2018 IPR004804 tRNA-guanine(15) transglycosylase GO:0006400|GO:0016763 MetaCyc: PWY-6711|MetaCyc: PWY-7923 DFR85_11185 f301ce6b8d5681c3f9bf85615c7a2bd4 254 Pfam PF03029 Conserved hypothetical ATP binding protein 7 239 1.4E-54 T 31-10-2018 IPR004130 GPN-loop GTPase DFR85_11185 f301ce6b8d5681c3f9bf85615c7a2bd4 254 SUPERFAMILY SSF52540 3 238 9.06E-36 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_11185 f301ce6b8d5681c3f9bf85615c7a2bd4 254 Gene3D G3DSA:3.40.50.300 1 252 1.2E-58 T 31-10-2018 DFR85_07335 5ea552257503e348a0b5b146aeb1fa49 427 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 72 411 3.1E-36 T 31-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme DFR85_07335 5ea552257503e348a0b5b146aeb1fa49 427 SUPERFAMILY SSF53686 46 423 1.51E-94 T 31-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme DFR85_07335 5ea552257503e348a0b5b146aeb1fa49 427 PIRSF PIRSF001413 8 427 1.1E-142 T 31-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 DFR85_07335 5ea552257503e348a0b5b146aeb1fa49 427 Gene3D G3DSA:3.40.50.1100 12 417 2.0E-156 T 31-10-2018 DFR85_07335 5ea552257503e348a0b5b146aeb1fa49 427 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 102 116 - T 31-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 DFR85_07335 5ea552257503e348a0b5b146aeb1fa49 427 PIRSF PIRSF500824 1 427 5.5E-189 T 31-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 DFR85_07335 5ea552257503e348a0b5b146aeb1fa49 427 Gene3D G3DSA:3.40.50.1100 13 234 2.0E-156 T 31-10-2018 DFR85_07335 5ea552257503e348a0b5b146aeb1fa49 427 TIGRFAM TIGR01415 trpB_rel: pyridoxal-phosphate dependent TrpB-like enzyme 12 426 1.3E-196 T 31-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 DFR85_07055 5eeb5c155e2e64abc409fae044892711 138 ProSitePatterns PS00049 Ribosomal protein L14 signature. 77 103 - T 31-10-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07055 5eeb5c155e2e64abc409fae044892711 138 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 17 138 20.452 T 31-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 DFR85_07055 5eeb5c155e2e64abc409fae044892711 138 Gene3D G3DSA:2.40.150.20 3 138 4.5E-47 T 31-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 DFR85_07055 5eeb5c155e2e64abc409fae044892711 138 SMART SM01374 17 138 4.4E-58 T 31-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 DFR85_07055 5eeb5c155e2e64abc409fae044892711 138 Pfam PF00238 Ribosomal protein L14p/L23e 18 137 5.5E-35 T 31-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 DFR85_07055 5eeb5c155e2e64abc409fae044892711 138 TIGRFAM TIGR03673 uL14_arch: 50S ribosomal protein uL14 10 138 8.8E-59 T 31-10-2018 IPR019971 Ribosomal protein L14P, archaeal DFR85_07055 5eeb5c155e2e64abc409fae044892711 138 SUPERFAMILY SSF50193 12 138 1.96E-43 T 31-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 DFR85_07545 17af96cac9c2110aa6994a1949a80e67 190 SUPERFAMILY SSF54631 65 183 3.28E-23 T 31-10-2018 DFR85_07545 17af96cac9c2110aa6994a1949a80e67 190 Pfam PF00571 CBS domain 66 120 7.7E-10 T 31-10-2018 IPR000644 CBS domain DFR85_07545 17af96cac9c2110aa6994a1949a80e67 190 Pfam PF00571 CBS domain 138 182 7.8E-6 T 31-10-2018 IPR000644 CBS domain DFR85_07545 17af96cac9c2110aa6994a1949a80e67 190 SUPERFAMILY SSF47413 7 55 1.15E-13 T 31-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 DFR85_07545 17af96cac9c2110aa6994a1949a80e67 190 SMART SM00116 72 120 5.5E-8 T 31-10-2018 IPR000644 CBS domain DFR85_07545 17af96cac9c2110aa6994a1949a80e67 190 SMART SM00116 136 182 0.27 T 31-10-2018 IPR000644 CBS domain DFR85_07545 17af96cac9c2110aa6994a1949a80e67 190 PIRSF PIRSF037253 1 185 3.3E-47 T 31-10-2018 IPR017158 Transcription regulator, CBS domain-containing, predicted DFR85_07545 17af96cac9c2110aa6994a1949a80e67 190 Gene3D G3DSA:3.10.580.10 61 183 2.1E-21 T 31-10-2018 DFR85_07545 17af96cac9c2110aa6994a1949a80e67 190 SMART SM00530 7 61 1.9E-12 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DFR85_07545 17af96cac9c2110aa6994a1949a80e67 190 Pfam PF01381 Helix-turn-helix 8 52 1.9E-13 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 DFR85_07545 17af96cac9c2110aa6994a1949a80e67 190 Gene3D G3DSA:1.10.260.40 5 60 7.1E-15 T 31-10-2018 DFR85_12720 b37e123575ad9b04e52e13abcc315f05 889 Gene3D G3DSA:3.20.110.20 376 675 1.6E-26 T 31-10-2018 DFR85_12720 b37e123575ad9b04e52e13abcc315f05 889 SUPERFAMILY SSF88713 331 659 2.54E-62 T 31-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 DFR85_12720 b37e123575ad9b04e52e13abcc315f05 889 Pfam PF03065 Glycosyl hydrolase family 57 336 680 3.4E-41 T 31-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 DFR85_04165 4f1eef38e3522df969769c41e148884d 286 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 285 8.3E-25 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 DFR85_04165 4f1eef38e3522df969769c41e148884d 286 SUPERFAMILY SSF161098 77 258 3.66E-16 T 31-10-2018 IPR035906 MetI-like superfamily DFR85_04165 4f1eef38e3522df969769c41e148884d 286 Gene3D G3DSA:1.10.3720.10 69 277 2.3E-11 T 31-10-2018 IPR035906 MetI-like superfamily DFR85_06670 e665affeb10d0153e0b2456a80a556c7 360 Gene3D G3DSA:3.30.70.3160 36 118 2.0E-7 T 31-10-2018 DFR85_06670 e665affeb10d0153e0b2456a80a556c7 360 Gene3D G3DSA:1.10.1510.30 158 244 6.0E-16 T 31-10-2018 DFR85_06670 e665affeb10d0153e0b2456a80a556c7 360 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 292 351 5.9E-6 T 31-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 DFR85_06670 e665affeb10d0153e0b2456a80a556c7 360 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 17 266 8.2E-51 T 31-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 DFR85_06670 e665affeb10d0153e0b2456a80a556c7 360 Gene3D G3DSA:3.30.2350.20 284 357 3.8E-6 T 31-10-2018 DFR85_06670 e665affeb10d0153e0b2456a80a556c7 360 SUPERFAMILY SSF55120 17 353 4.32E-45 T 31-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 DFR85_08180 c58a16449d147ed1dcf9e6cc0da82097 115 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 17 86 1.8E-13 T 31-10-2018 IPR002831 Transcription regulator TrmB, N-terminal DFR85_08180 c58a16449d147ed1dcf9e6cc0da82097 115 SUPERFAMILY SSF46785 16 112 8.68E-14 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_08180 c58a16449d147ed1dcf9e6cc0da82097 115 Gene3D G3DSA:1.10.10.10 6 113 5.2E-20 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_04280 7b423b51f5666a0df38d09df9739ca6e 252 SUPERFAMILY SSF53448 1 244 1.71E-47 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_04280 7b423b51f5666a0df38d09df9739ca6e 252 Gene3D G3DSA:3.90.550.10 1 251 1.9E-58 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_04280 7b423b51f5666a0df38d09df9739ca6e 252 Pfam PF00483 Nucleotidyl transferase 3 247 1.3E-22 T 31-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 DFR85_05485 d4290995ad95754d4927f71c7fa1384d 325 TIGRFAM TIGR03171 soxL2: Rieske iron-sulfur protein SoxL2 2 322 1.7E-187 T 31-10-2018 IPR017586 Rieske iron-sulphur protein SoxL2 DFR85_05485 d4290995ad95754d4927f71c7fa1384d 325 SUPERFAMILY SSF50022 97 280 8.93E-26 T 31-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 DFR85_05485 d4290995ad95754d4927f71c7fa1384d 325 Gene3D G3DSA:2.102.10.10 93 318 4.4E-54 T 31-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 DFR85_05485 d4290995ad95754d4927f71c7fa1384d 325 Pfam PF00355 Rieske [2Fe-2S] domain 164 262 6.5E-6 T 31-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DFR85_00235 d8a1e16df1bd8940af90d23832581d14 223 Pfam PF06525 Sulfocyanin (SoxE) domain 77 221 9.0E-59 T 31-10-2018 IPR010532 Sulfocyanin GO:0005507|GO:0055114 DFR85_00235 d8a1e16df1bd8940af90d23832581d14 223 TIGRFAM TIGR03094 sulfo_cyanin: sulfocyanin 64 222 4.3E-52 T 31-10-2018 IPR010532 Sulfocyanin GO:0005507|GO:0055114 DFR85_00235 d8a1e16df1bd8940af90d23832581d14 223 PIRSF PIRSF022145 1 223 6.2E-76 T 31-10-2018 IPR010532 Sulfocyanin GO:0005507|GO:0055114 DFR85_00235 d8a1e16df1bd8940af90d23832581d14 223 Gene3D G3DSA:2.60.40.420 45 210 1.4E-21 T 31-10-2018 IPR008972 Cupredoxin DFR85_00235 d8a1e16df1bd8940af90d23832581d14 223 ProSitePatterns PS00079 Multicopper oxidases signature 1. 189 209 - T 31-10-2018 IPR033138 Multicopper oxidases, conserved site DFR85_00235 d8a1e16df1bd8940af90d23832581d14 223 SUPERFAMILY SSF49503 81 210 7.6E-17 T 31-10-2018 IPR008972 Cupredoxin DFR85_03170 46270bfcdef2c967952469a3342aadfb 549 SUPERFAMILY SSF161098 44 249 1.01E-37 T 31-10-2018 IPR035906 MetI-like superfamily DFR85_03170 46270bfcdef2c967952469a3342aadfb 549 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 61 260 6.2E-12 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 DFR85_03170 46270bfcdef2c967952469a3342aadfb 549 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 369 532 3.9E-8 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 DFR85_03170 46270bfcdef2c967952469a3342aadfb 549 SUPERFAMILY SSF161098 277 547 3.18E-36 T 31-10-2018 IPR035906 MetI-like superfamily DFR85_03170 46270bfcdef2c967952469a3342aadfb 549 Gene3D G3DSA:1.10.3720.10 42 265 8.3E-40 T 31-10-2018 IPR035906 MetI-like superfamily DFR85_03170 46270bfcdef2c967952469a3342aadfb 549 Gene3D G3DSA:1.10.3720.10 273 533 1.3E-30 T 31-10-2018 IPR035906 MetI-like superfamily DFR85_12650 ee0b7e31369049480f4902d5e1bce5d4 462 SUPERFAMILY SSF103473 14 445 5.62E-76 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_12650 ee0b7e31369049480f4902d5e1bce5d4 462 ProSitePatterns PS00217 Sugar transport proteins signature 2. 122 147 - T 31-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DFR85_12650 ee0b7e31369049480f4902d5e1bce5d4 462 Pfam PF00083 Sugar (and other) transporter 38 444 3.7E-63 T 31-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 DFR85_12650 ee0b7e31369049480f4902d5e1bce5d4 462 Gene3D G3DSA:1.10.286.90 208 242 3.5E-8 T 31-10-2018 DFR85_10415 4395868d513e8bb1951f454ef57aca7d 330 SMART SM00966 17 63 2.8E-7 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR85_10415 4395868d513e8bb1951f454ef57aca7d 330 SUPERFAMILY SSF89447 14 54 8.55E-5 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily DFR85_10415 4395868d513e8bb1951f454ef57aca7d 330 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 19 57 6.4E-8 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR85_06475 6d5bc6e43406752c3f791c2eaffa43cb 255 SUPERFAMILY SSF53448 3 247 5.03E-49 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_06475 6d5bc6e43406752c3f791c2eaffa43cb 255 Pfam PF00483 Nucleotidyl transferase 4 247 2.2E-26 T 31-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 DFR85_06475 6d5bc6e43406752c3f791c2eaffa43cb 255 Gene3D G3DSA:3.90.550.10 1 254 1.5E-57 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_01805 e15ba3cdf7610a78ec0064302b57c902 537 Gene3D G3DSA:1.20.210.10 16 534 1.4E-84 T 31-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_01805 e15ba3cdf7610a78ec0064302b57c902 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 243 264 6.6E-8 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_01805 e15ba3cdf7610a78ec0064302b57c902 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 140 152 6.6E-8 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_01805 e15ba3cdf7610a78ec0064302b57c902 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 427 448 6.6E-8 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_01805 e15ba3cdf7610a78ec0064302b57c902 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 376 395 6.6E-8 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_01805 e15ba3cdf7610a78ec0064302b57c902 537 PRINTS PR01165 Cytochrome c oxidase subunit I signature 66 89 6.6E-8 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_01805 e15ba3cdf7610a78ec0064302b57c902 537 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 25 471 1.6E-75 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_01805 e15ba3cdf7610a78ec0064302b57c902 537 SUPERFAMILY SSF81442 25 493 5.89E-90 T 31-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_08715 c0f706d8933c122fd030bc505229887c 226 Pfam PF13483 Beta-lactamase superfamily domain 4 190 2.1E-20 T 31-10-2018 DFR85_08715 c0f706d8933c122fd030bc505229887c 226 SUPERFAMILY SSF56281 4 225 1.11E-30 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR85_08715 c0f706d8933c122fd030bc505229887c 226 Hamap MF_00457 UPF0173 metal-dependent hydrolase . 2 226 33.914 T 31-10-2018 IPR022877 Protein of unknown funcion UPF0173 DFR85_08715 c0f706d8933c122fd030bc505229887c 226 SMART SM00849 8 190 6.3E-10 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR85_08715 c0f706d8933c122fd030bc505229887c 226 Gene3D G3DSA:3.60.15.10 3 226 6.7E-64 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR85_01410 0184676dcc20c8c28511584a5a312245 355 SUPERFAMILY SSF103473 6 350 6.15E-36 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_01410 0184676dcc20c8c28511584a5a312245 355 Pfam PF07690 Major Facilitator Superfamily 7 309 3.0E-24 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_01410 0184676dcc20c8c28511584a5a312245 355 Gene3D G3DSA:1.20.1250.20 181 352 3.7E-9 T 31-10-2018 DFR85_01410 0184676dcc20c8c28511584a5a312245 355 Gene3D G3DSA:1.20.1250.20 6 180 1.0E-22 T 31-10-2018 DFR85_07285 b1b9ed947fbbeee20ed41c7c66acaabb 303 SUPERFAMILY SSF53335 3 285 4.85E-78 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR85_07285 b1b9ed947fbbeee20ed41c7c66acaabb 303 Pfam PF17284 Spermidine synthase tetramerisation domain 7 56 2.1E-5 T 31-10-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 DFR85_07285 b1b9ed947fbbeee20ed41c7c66acaabb 303 Pfam PF01564 Spermine/spermidine synthase domain 61 243 5.5E-48 T 31-10-2018 DFR85_07285 b1b9ed947fbbeee20ed41c7c66acaabb 303 Gene3D G3DSA:2.30.140.10 4 55 1.8E-10 T 31-10-2018 IPR037163 Spermidine synthase, tetramerisation domain superfamily KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 DFR85_07285 b1b9ed947fbbeee20ed41c7c66acaabb 303 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 6 288 34.87 T 31-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 DFR85_07285 b1b9ed947fbbeee20ed41c7c66acaabb 303 Gene3D G3DSA:3.40.50.150 59 302 2.2E-76 T 31-10-2018 DFR85_07285 b1b9ed947fbbeee20ed41c7c66acaabb 303 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 82 95 - T 31-10-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 DFR85_14070 8acc3f49e9ffe9aeb64f0d2e0efd4cf1 171 Pfam PF01750 Hydrogenase maturation protease 23 141 2.6E-14 T 31-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 DFR85_14070 8acc3f49e9ffe9aeb64f0d2e0efd4cf1 171 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 4 146 8.7E-26 T 31-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 DFR85_14070 8acc3f49e9ffe9aeb64f0d2e0efd4cf1 171 Gene3D G3DSA:3.40.50.1450 1 148 6.1E-27 T 31-10-2018 IPR023430 Peptidase HybD-like domain superfamily DFR85_14070 8acc3f49e9ffe9aeb64f0d2e0efd4cf1 171 PRINTS PR00446 Hydrogen uptake protein signature 15 26 1.1E-5 T 31-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 DFR85_14070 8acc3f49e9ffe9aeb64f0d2e0efd4cf1 171 PRINTS PR00446 Hydrogen uptake protein signature 52 62 1.1E-5 T 31-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 DFR85_14070 8acc3f49e9ffe9aeb64f0d2e0efd4cf1 171 PRINTS PR00446 Hydrogen uptake protein signature 3 15 1.1E-5 T 31-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 DFR85_14070 8acc3f49e9ffe9aeb64f0d2e0efd4cf1 171 SUPERFAMILY SSF53163 1 154 7.85E-26 T 31-10-2018 IPR023430 Peptidase HybD-like domain superfamily DFR85_03665 3667571714926893c925a13100f4a3ab 101 Gene3D G3DSA:1.10.10.10 10 75 2.0E-5 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_06060 d008da765d7e1f9739eafcb30f18b089 452 SUPERFAMILY SSF51905 5 359 4.25E-33 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_06060 d008da765d7e1f9739eafcb30f18b089 452 Gene3D G3DSA:3.50.50.60 1 452 1.8E-169 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_06060 d008da765d7e1f9739eafcb30f18b089 452 Pfam PF01494 FAD binding domain 6 177 1.2E-6 T 31-10-2018 IPR002938 FAD-binding domain GO:0071949 DFR85_06060 d008da765d7e1f9739eafcb30f18b089 452 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 6 313 6.4E-55 T 31-10-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 DFR85_06060 d008da765d7e1f9739eafcb30f18b089 452 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 280 295 2.4E-5 T 31-10-2018 DFR85_06060 d008da765d7e1f9739eafcb30f18b089 452 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 2.4E-5 T 31-10-2018 DFR85_10900 2a80bed8e23ce23d25110e5212c3a049 482 Gene3D G3DSA:3.90.1860.10 1 482 1.6E-194 T 31-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 DFR85_10900 2a80bed8e23ce23d25110e5212c3a049 482 Pfam PF01139 tRNA-splicing ligase RtcB 47 482 1.5E-162 T 31-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 DFR85_10900 2a80bed8e23ce23d25110e5212c3a049 482 SUPERFAMILY SSF103365 6 482 2.09E-171 T 31-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 DFR85_04380 2d7cc275c07ee7172deb438f527c19f5 306 SUPERFAMILY SSF53448 4 252 7.07E-18 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_04380 2d7cc275c07ee7172deb438f527c19f5 306 Pfam PF00535 Glycosyl transferase family 2 4 132 3.2E-8 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 DFR85_04380 2d7cc275c07ee7172deb438f527c19f5 306 Gene3D G3DSA:3.90.550.10 3 198 4.6E-12 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_09240 fb9de56e4c4e6bc6632ecc5dcde3d36f 391 Gene3D G3DSA:3.90.1260.10 170 390 9.7E-73 T 31-10-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 DFR85_09240 fb9de56e4c4e6bc6632ecc5dcde3d36f 391 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 114 125 - T 31-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 DFR85_09240 fb9de56e4c4e6bc6632ecc5dcde3d36f 391 SUPERFAMILY SSF69864 168 389 1.05E-74 T 31-10-2018 DFR85_09240 fb9de56e4c4e6bc6632ecc5dcde3d36f 391 SUPERFAMILY SSF52402 1 201 1.3E-42 T 31-10-2018 DFR85_09240 fb9de56e4c4e6bc6632ecc5dcde3d36f 391 Gene3D G3DSA:3.40.50.620 1 169 2.0E-58 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR85_09240 fb9de56e4c4e6bc6632ecc5dcde3d36f 391 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 6 14 - T 31-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 DFR85_09240 fb9de56e4c4e6bc6632ecc5dcde3d36f 391 TIGRFAM TIGR00032 argG: argininosuccinate synthase 2 384 1.3E-132 T 31-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 DFR85_09240 fb9de56e4c4e6bc6632ecc5dcde3d36f 391 Pfam PF00764 Arginosuccinate synthase 4 382 1.5E-140 T 31-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 DFR85_09240 fb9de56e4c4e6bc6632ecc5dcde3d36f 391 Hamap MF_00005 Argininosuccinate synthase [argG]. 1 390 44.895 T 31-10-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 DFR85_06795 f06a9c4c0a33a1f8fc16ad941528d3e3 596 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 15 367 1.2E-27 T 31-10-2018 DFR85_06795 f06a9c4c0a33a1f8fc16ad941528d3e3 596 Pfam PF05670 Domain of unknown function (DUF814) 385 484 1.5E-24 T 31-10-2018 IPR008532 Domain of unknown function DUF814 DFR85_06795 f06a9c4c0a33a1f8fc16ad941528d3e3 596 Gene3D G3DSA:2.30.310.10 4 147 3.1E-9 T 31-10-2018 DFR85_10665 ae0dbf301fe340da280a30a84d373838 239 SUPERFAMILY SSF46785 31 94 4.43E-8 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_10445 69d57c5a980c69932b2bb33bd164a893 503 Gene3D G3DSA:3.40.640.10 86 349 2.0E-80 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR85_10445 69d57c5a980c69932b2bb33bd164a893 503 Pfam PF02347 Glycine cleavage system P-protein 32 303 2.4E-14 T 31-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 DFR85_10445 69d57c5a980c69932b2bb33bd164a893 503 SUPERFAMILY SSF53383 37 479 7.09E-101 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase DFR85_07005 8c52d41269bc7b3add91a24ea0c69c99 214 SUPERFAMILY SSF54768 48 119 1.88E-18 T 31-10-2018 DFR85_07005 8c52d41269bc7b3add91a24ea0c69c99 214 TIGRFAM TIGR01020 uS5_euk_arch: ribosomal protein uS5 9 213 1.1E-93 T 31-10-2018 IPR005711 Ribosomal protein S5, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-3214858|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8876725|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07005 8c52d41269bc7b3add91a24ea0c69c99 214 ProSitePatterns PS00585 Ribosomal protein S5 signature. 71 103 - T 31-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site DFR85_07005 8c52d41269bc7b3add91a24ea0c69c99 214 Pfam PF03719 Ribosomal protein S5, C-terminal domain 140 207 4.5E-20 T 31-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 DFR85_07005 8c52d41269bc7b3add91a24ea0c69c99 214 Gene3D G3DSA:3.30.160.770 12 116 1.9E-37 T 31-10-2018 DFR85_07005 8c52d41269bc7b3add91a24ea0c69c99 214 Gene3D G3DSA:3.30.230.10 117 212 5.0E-33 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup DFR85_07005 8c52d41269bc7b3add91a24ea0c69c99 214 SUPERFAMILY SSF54211 132 211 9.61E-20 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold DFR85_07005 8c52d41269bc7b3add91a24ea0c69c99 214 Hamap MF_01307_A 30S ribosomal protein S5 [rpsE]. 6 206 46.67 T 31-10-2018 IPR005711 Ribosomal protein S5, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-3214858|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8876725|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07005 8c52d41269bc7b3add91a24ea0c69c99 214 Pfam PF00333 Ribosomal protein S5, N-terminal domain 54 118 1.2E-22 T 31-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 DFR85_14305 5aa0ba501e0a5d3d82b633972150ade7 152 Gene3D G3DSA:3.40.30.10 2 151 7.0E-51 T 31-10-2018 DFR85_14305 5aa0ba501e0a5d3d82b633972150ade7 152 Pfam PF00578 AhpC/TSA family 5 125 1.4E-40 T 31-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 DFR85_14305 5aa0ba501e0a5d3d82b633972150ade7 152 PIRSF PIRSF000239 1 152 8.5E-31 T 31-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 DFR85_14305 5aa0ba501e0a5d3d82b633972150ade7 152 SUPERFAMILY SSF52833 1 147 3.95E-52 T 31-10-2018 IPR036249 Thioredoxin-like superfamily DFR85_01380 2950a7619b89fe843fb58f6e78f4d4e7 113 Pfam PF04032 RNAse P Rpr2/Rpp21/SNM1 subunit domain 26 85 2.1E-12 T 31-10-2018 IPR007175 RNAse P, Rpr2/Rpp21 subunit Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 DFR85_01380 2950a7619b89fe843fb58f6e78f4d4e7 113 PIRSF PIRSF004878 1 101 2.5E-27 T 31-10-2018 IPR016432 Ribonuclease P, protein component 4 GO:0001682|GO:0004526 DFR85_01380 2950a7619b89fe843fb58f6e78f4d4e7 113 Hamap MF_00757 Ribonuclease P protein component 4 [rnp4]. 1 94 21.637 T 31-10-2018 IPR016432 Ribonuclease P, protein component 4 GO:0001682|GO:0004526 DFR85_01380 2950a7619b89fe843fb58f6e78f4d4e7 113 Gene3D G3DSA:2.20.25.200 52 111 5.9E-13 T 31-10-2018 DFR85_01380 2950a7619b89fe843fb58f6e78f4d4e7 113 Gene3D G3DSA:1.20.5.420 1 51 1.5E-5 T 31-10-2018 DFR85_12015 56a94eae6f9d3ab4d47e3327b78c5f6e 552 Gene3D G3DSA:3.40.50.12780 25 430 2.2E-69 T 31-10-2018 DFR85_12015 56a94eae6f9d3ab4d47e3327b78c5f6e 552 Pfam PF00501 AMP-binding enzyme 58 436 9.5E-70 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 DFR85_12015 56a94eae6f9d3ab4d47e3327b78c5f6e 552 ProSitePatterns PS00455 Putative AMP-binding domain signature. 194 205 - T 31-10-2018 IPR020845 AMP-binding, conserved site DFR85_12015 56a94eae6f9d3ab4d47e3327b78c5f6e 552 SUPERFAMILY SSF56801 2 548 1.83E-121 T 31-10-2018 DFR85_12015 56a94eae6f9d3ab4d47e3327b78c5f6e 552 Pfam PF13193 AMP-binding enzyme C-terminal domain 445 516 7.0E-16 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain DFR85_12015 56a94eae6f9d3ab4d47e3327b78c5f6e 552 Gene3D G3DSA:3.30.300.30 432 552 3.5E-24 T 31-10-2018 DFR85_12015 56a94eae6f9d3ab4d47e3327b78c5f6e 552 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 3 50 4.7E-12 T 31-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 DFR85_10010 3b9a45bdf987f23cc88d16f725e86382 251 SUPERFAMILY SSF56281 33 243 9.7E-34 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR85_10010 3b9a45bdf987f23cc88d16f725e86382 251 Gene3D G3DSA:3.60.15.10 4 244 1.0E-43 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR85_10010 3b9a45bdf987f23cc88d16f725e86382 251 Pfam PF00753 Metallo-beta-lactamase superfamily 33 223 4.3E-14 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR85_10010 3b9a45bdf987f23cc88d16f725e86382 251 SMART SM00849 32 223 1.5E-19 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR85_04915 279997f11f927a2a9447c970336edf5a 214 Pfam PF10108 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB 63 191 3.4E-6 T 31-10-2018 IPR019288 Predicted 3'-5' exonuclease, PolB-like DFR85_04915 279997f11f927a2a9447c970336edf5a 214 SUPERFAMILY SSF53098 4 199 8.22E-15 T 31-10-2018 IPR012337 Ribonuclease H-like superfamily DFR85_04915 279997f11f927a2a9447c970336edf5a 214 Gene3D G3DSA:3.30.420.10 3 194 1.0E-11 T 31-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 DFR85_15555 a6735d7c6c86b203c57b0f9a079c123e 314 SUPERFAMILY SSF64307 126 203 1.83E-13 T 31-10-2018 IPR036868 TusA-like domain superfamily DFR85_15555 a6735d7c6c86b203c57b0f9a079c123e 314 Gene3D G3DSA:3.30.110.40 132 203 2.9E-9 T 31-10-2018 IPR036868 TusA-like domain superfamily DFR85_15555 a6735d7c6c86b203c57b0f9a079c123e 314 Pfam PF01206 Sulfurtransferase TusA 135 196 1.8E-12 T 31-10-2018 IPR001455 TusA-like domain DFR85_07960 aba1a87fd21f5b6f55be1d7a750ffe3e 415 SUPERFAMILY SSF53649 1 374 8.47E-37 T 31-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 DFR85_07960 aba1a87fd21f5b6f55be1d7a750ffe3e 415 Gene3D G3DSA:3.40.720.10 7 400 2.0E-125 T 31-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 DFR85_07960 aba1a87fd21f5b6f55be1d7a750ffe3e 415 TIGRFAM TIGR00306 apgM: phosphoglycerate mutase (2,3-diphosphoglycerate-independent), archaeal form 7 405 1.1E-129 T 31-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DFR85_07960 aba1a87fd21f5b6f55be1d7a750ffe3e 415 Hamap MF_01402_A 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [apgM]. 4 406 43.061 T 31-10-2018 IPR023665 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, prokaryotes GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DFR85_07960 aba1a87fd21f5b6f55be1d7a750ffe3e 415 PIRSF PIRSF006392 1 411 6.0E-148 T 31-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DFR85_07960 aba1a87fd21f5b6f55be1d7a750ffe3e 415 Pfam PF01676 Metalloenzyme superfamily 5 403 1.4E-44 T 31-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 DFR85_07960 aba1a87fd21f5b6f55be1d7a750ffe3e 415 Gene3D G3DSA:3.30.70.2130 81 234 2.0E-125 T 31-10-2018 DFR85_07960 aba1a87fd21f5b6f55be1d7a750ffe3e 415 Pfam PF10143 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 42 212 4.7E-54 T 31-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 DFR85_01620 6839f9977a78dbd7a1ee24103441e27a 432 Pfam PF05317 Thermopsin 42 246 1.0E-24 T 31-10-2018 IPR007981 Peptidase A5, thermopsin DFR85_09615 391baeca9cad37d0eef26d34c6c2c1c5 571 Gene3D G3DSA:1.10.730.10 379 547 1.0E-37 T 31-10-2018 DFR85_09615 391baeca9cad37d0eef26d34c6c2c1c5 571 Gene3D G3DSA:3.40.50.620 4 378 1.8E-145 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR85_09615 391baeca9cad37d0eef26d34c6c2c1c5 571 SUPERFAMILY SSF57770 139 173 5.36E-12 T 31-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 DFR85_09615 391baeca9cad37d0eef26d34c6c2c1c5 571 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 4 543 5.1E-154 T 31-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 DFR85_09615 391baeca9cad37d0eef26d34c6c2c1c5 571 SUPERFAMILY SSF47323 384 543 2.24E-31 T 31-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR85_09615 391baeca9cad37d0eef26d34c6c2c1c5 571 Pfam PF09334 tRNA synthetases class I (M) 4 396 1.6E-151 T 31-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR85_09615 391baeca9cad37d0eef26d34c6c2c1c5 571 Gene3D G3DSA:2.20.28.20 139 173 1.8E-145 T 31-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 DFR85_09615 391baeca9cad37d0eef26d34c6c2c1c5 571 Hamap MF_00098 Methionine--tRNA ligase [metG]. 1 564 37.697 T 31-10-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 DFR85_09615 391baeca9cad37d0eef26d34c6c2c1c5 571 SUPERFAMILY SSF52374 2 383 5.0E-82 T 31-10-2018 DFR85_09615 391baeca9cad37d0eef26d34c6c2c1c5 571 PRINTS PR01041 Methionyl-tRNA synthetase signature 250 261 4.6E-19 T 31-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 DFR85_09615 391baeca9cad37d0eef26d34c6c2c1c5 571 PRINTS PR01041 Methionyl-tRNA synthetase signature 289 304 4.6E-19 T 31-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 DFR85_09615 391baeca9cad37d0eef26d34c6c2c1c5 571 PRINTS PR01041 Methionyl-tRNA synthetase signature 383 394 4.6E-19 T 31-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 DFR85_09615 391baeca9cad37d0eef26d34c6c2c1c5 571 PRINTS PR01041 Methionyl-tRNA synthetase signature 89 100 4.6E-19 T 31-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 DFR85_09615 391baeca9cad37d0eef26d34c6c2c1c5 571 PRINTS PR01041 Methionyl-tRNA synthetase signature 5 18 4.6E-19 T 31-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 DFR85_08200 3f828cf7a9f40030210f6bd18ec79da3 382 Gene3D G3DSA:1.10.240.10 259 382 1.1E-44 T 31-10-2018 DFR85_08200 3f828cf7a9f40030210f6bd18ec79da3 382 Hamap MF_00140_A Tryptophan--tRNA ligase [trpS]. 7 369 43.045 T 31-10-2018 IPR020653 Tryptophan-tRNA ligase, archaea GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 DFR85_08200 3f828cf7a9f40030210f6bd18ec79da3 382 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 74 380 1.6E-86 T 31-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 DFR85_08200 3f828cf7a9f40030210f6bd18ec79da3 382 SUPERFAMILY SSF52374 7 362 2.25E-92 T 31-10-2018 DFR85_08200 3f828cf7a9f40030210f6bd18ec79da3 382 Pfam PF00579 tRNA synthetases class I (W and Y) 75 349 3.8E-27 T 31-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR85_08200 3f828cf7a9f40030210f6bd18ec79da3 382 Gene3D G3DSA:3.40.50.620 2 258 3.4E-105 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR85_08200 3f828cf7a9f40030210f6bd18ec79da3 382 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 255 265 8.0E-22 T 31-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 DFR85_08200 3f828cf7a9f40030210f6bd18ec79da3 382 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 211 232 8.0E-22 T 31-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 DFR85_08200 3f828cf7a9f40030210f6bd18ec79da3 382 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 87 103 8.0E-22 T 31-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 DFR85_08200 3f828cf7a9f40030210f6bd18ec79da3 382 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 140 159 8.0E-22 T 31-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 DFR85_09040 1a39ca0306452e4734b0ebe42392d5c9 224 Gene3D G3DSA:3.40.50.620 1 127 2.4E-36 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR85_09040 1a39ca0306452e4734b0ebe42392d5c9 224 TIGRFAM TIGR03679 arCOG00187: arCOG00187 universal archaeal metal-binding-domain/4Fe-4S-binding-domain containing ABC transporter, ATP-binding protein 6 222 8.8E-80 T 31-10-2018 IPR022427 Uncharacterised protein MJ0570, ATP-binding DFR85_09040 1a39ca0306452e4734b0ebe42392d5c9 224 SUPERFAMILY SSF52402 4 218 4.93E-65 T 31-10-2018 DFR85_09040 1a39ca0306452e4734b0ebe42392d5c9 224 PIRSF PIRSF039123 2 224 4.8E-69 T 31-10-2018 IPR030662 Diphthine--ammonia ligase/Uncharacterised protein MJ0570 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 DFR85_09040 1a39ca0306452e4734b0ebe42392d5c9 224 TIGRFAM TIGR00290 MJ0570_dom: MJ0570-related uncharacterized domain 6 222 7.7E-59 T 31-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 DFR85_09040 1a39ca0306452e4734b0ebe42392d5c9 224 Gene3D G3DSA:3.90.1490.10 128 224 1.1E-21 T 31-10-2018 DFR85_09040 1a39ca0306452e4734b0ebe42392d5c9 224 Pfam PF01902 Diphthamide synthase 6 222 2.2E-58 T 31-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 DFR85_12460 acdd7c5be849d3a901706898028da042 313 Pfam PF00756 Putative esterase 23 291 2.9E-13 T 31-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 DFR85_12460 acdd7c5be849d3a901706898028da042 313 SUPERFAMILY SSF53474 20 293 8.87E-28 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold DFR85_12460 acdd7c5be849d3a901706898028da042 313 Gene3D G3DSA:3.40.50.1820 16 306 1.6E-33 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold DFR85_05480 2b7b7aa2fdb02a6c7e9682213821369b 312 TIGRFAM TIGR03155 sulfolob_CbsB: cytochrome b558/566, subunit B 8 302 3.4E-73 T 31-10-2018 IPR017573 Cytochrome b558/566, subunit B DFR85_07880 27a82111b10fcdd38807ab9edcd5aae9 220 SUPERFAMILY SSF55821 7 216 1.21E-48 T 31-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily DFR85_07880 27a82111b10fcdd38807ab9edcd5aae9 220 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 8 215 2.3E-44 T 31-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 DFR85_07880 27a82111b10fcdd38807ab9edcd5aae9 220 Gene3D G3DSA:3.90.870.10 4 219 1.9E-54 T 31-10-2018 DFR85_09785 d7b41e2f0c3ad5f1be155d0452f1df69 206 Hamap MF_00214 3-dehydroquinate dehydratase [aroD]. 4 203 28.771 T 31-10-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 DFR85_09785 d7b41e2f0c3ad5f1be155d0452f1df69 206 SUPERFAMILY SSF51569 3 203 4.03E-33 T 31-10-2018 DFR85_09785 d7b41e2f0c3ad5f1be155d0452f1df69 206 Gene3D G3DSA:3.20.20.70 11 204 5.8E-28 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_09785 d7b41e2f0c3ad5f1be155d0452f1df69 206 Pfam PF01487 Type I 3-dehydroquinase 14 199 2.5E-17 T 31-10-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 DFR85_02260 bf6d3e51f866632899f289eb718e634b 262 Pfam PF13614 AAA domain 3 127 2.6E-13 T 31-10-2018 IPR025669 AAA domain DFR85_02260 bf6d3e51f866632899f289eb718e634b 262 SUPERFAMILY SSF52540 1 227 6.46E-21 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_02260 bf6d3e51f866632899f289eb718e634b 262 Gene3D G3DSA:3.40.50.300 2 216 7.6E-22 T 31-10-2018 DFR85_12560 d165d56eecce4550cf47f92ea250f7d5 446 Pfam PF07690 Major Facilitator Superfamily 44 396 5.0E-32 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_12560 d165d56eecce4550cf47f92ea250f7d5 446 SUPERFAMILY SSF103473 12 436 4.97E-64 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_12560 d165d56eecce4550cf47f92ea250f7d5 446 ProSitePatterns PS00216 Sugar transport proteins signature 1. 89 105 - T 31-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DFR85_12560 d165d56eecce4550cf47f92ea250f7d5 446 ProSitePatterns PS00216 Sugar transport proteins signature 1. 311 328 - T 31-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DFR85_12560 d165d56eecce4550cf47f92ea250f7d5 446 Gene3D G3DSA:1.20.1250.20 29 433 1.2E-47 T 31-10-2018 DFR85_15830 f47f8e1b4395bdc270a1e67e29bf6873 278 Gene3D G3DSA:3.20.20.60 3 278 3.1E-100 T 31-10-2018 DFR85_15830 f47f8e1b4395bdc270a1e67e29bf6873 278 TIGRFAM TIGR02317 prpB: methylisocitrate lyase 4 276 1.2E-115 T 31-10-2018 IPR012695 2-methylisocitrate lyase GO:0019629|GO:0046421 KEGG: 00640+4.1.3.30|MetaCyc: PWY-5747 DFR85_15830 f47f8e1b4395bdc270a1e67e29bf6873 278 SUPERFAMILY SSF51621 6 273 3.81E-91 T 31-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 DFR85_15830 f47f8e1b4395bdc270a1e67e29bf6873 278 ProSitePatterns PS00161 Isocitrate lyase signature. 108 113 - T 31-10-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824 DFR85_15830 f47f8e1b4395bdc270a1e67e29bf6873 278 Pfam PF13714 Phosphoenolpyruvate phosphomutase 7 237 9.6E-52 T 31-10-2018 DFR85_10060 4ccd0f3a58d0e045c481648504fbb522 296 Gene3D G3DSA:1.10.10.10 5 67 1.5E-6 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_10060 4ccd0f3a58d0e045c481648504fbb522 296 SUPERFAMILY SSF53850 65 240 5.88E-10 T 31-10-2018 DFR85_10060 4ccd0f3a58d0e045c481648504fbb522 296 SUPERFAMILY SSF46785 6 50 2.17E-8 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_10060 4ccd0f3a58d0e045c481648504fbb522 296 Pfam PF13412 Winged helix-turn-helix DNA-binding 7 46 1.4E-7 T 31-10-2018 DFR85_10060 4ccd0f3a58d0e045c481648504fbb522 296 Gene3D G3DSA:3.40.190.10 152 295 3.9E-9 T 31-10-2018 DFR85_10060 4ccd0f3a58d0e045c481648504fbb522 296 PIRSF PIRSF012876 1 296 3.0E-94 T 31-10-2018 IPR014466 Predicted transcriptional regulator, AF1742 type DFR85_14450 5a52c643e29974756bc0cdd80602dc0a 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.0E-39 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_14450 5a52c643e29974756bc0cdd80602dc0a 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.0E-39 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_14450 5a52c643e29974756bc0cdd80602dc0a 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.0E-39 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_14450 5a52c643e29974756bc0cdd80602dc0a 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.0E-39 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_14450 5a52c643e29974756bc0cdd80602dc0a 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 1.0E-39 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_14450 5a52c643e29974756bc0cdd80602dc0a 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 1.0E-39 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_14450 5a52c643e29974756bc0cdd80602dc0a 251 SUPERFAMILY SSF51735 7 247 2.3E-68 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_14450 5a52c643e29974756bc0cdd80602dc0a 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 3.5E-15 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_14450 5a52c643e29974756bc0cdd80602dc0a 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 3.5E-15 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_14450 5a52c643e29974756bc0cdd80602dc0a 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 3.5E-15 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR DFR85_14450 5a52c643e29974756bc0cdd80602dc0a 251 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 31-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 DFR85_14450 5a52c643e29974756bc0cdd80602dc0a 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 244 1.8E-51 T 31-10-2018 DFR85_14450 5a52c643e29974756bc0cdd80602dc0a 251 Gene3D G3DSA:3.40.50.720 1 250 4.6E-69 T 31-10-2018 DFR85_01135 9e5033bab6218999868840018ab64a7d 611 Pfam PF06202 Amylo-alpha-1,6-glucosidase 257 602 1.5E-107 T 31-10-2018 IPR032790 Glycogen debranching enzyme, C-terminal KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-6798695|Reactome: R-HSA-70221 DFR85_01135 9e5033bab6218999868840018ab64a7d 611 TIGRFAM TIGR01561 gde_arch: putative glycogen debranching enzyme, archaeal type 11 544 2.7E-189 T 31-10-2018 IPR006451 Glycogen debranching enzyme, archaeal type DFR85_01135 9e5033bab6218999868840018ab64a7d 611 Gene3D G3DSA:1.50.10.10 270 601 2.6E-27 T 31-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 DFR85_01135 9e5033bab6218999868840018ab64a7d 611 Pfam PF12439 Glycogen debranching enzyme N terminal 10 214 6.3E-54 T 31-10-2018 IPR024742 Glycogen debranching enzyme, bacterial and archaeal type, N-terminal DFR85_01135 9e5033bab6218999868840018ab64a7d 611 SUPERFAMILY SSF48208 178 606 1.21E-69 T 31-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 DFR85_05110 ab325b790df7eb71d337f1837c8641ec 713 Pfam PF05317 Thermopsin 142 397 3.3E-77 T 31-10-2018 IPR007981 Peptidase A5, thermopsin DFR85_10935 85231b9663cd13899794e6f70c5ccaa7 288 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 161 281 1.6E-26 T 31-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 DFR85_10935 85231b9663cd13899794e6f70c5ccaa7 288 Gene3D G3DSA:3.40.50.720 1 160 2.6E-37 T 31-10-2018 DFR85_10935 85231b9663cd13899794e6f70c5ccaa7 288 SUPERFAMILY SSF48179 160 284 1.59E-31 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 DFR85_10935 85231b9663cd13899794e6f70c5ccaa7 288 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 158 1.0E-33 T 31-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 DFR85_10935 85231b9663cd13899794e6f70c5ccaa7 288 SUPERFAMILY SSF51735 1 159 5.65E-37 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_10935 85231b9663cd13899794e6f70c5ccaa7 288 Gene3D G3DSA:1.10.1040.10 161 286 6.0E-32 T 31-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 DFR85_10935 85231b9663cd13899794e6f70c5ccaa7 288 PIRSF PIRSF000103 1 288 6.3E-69 T 31-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 DFR85_06055 f6232127e9ccff6392ec3cbb23979181 126 Gene3D G3DSA:3.40.50.11100 3 126 4.4E-49 T 31-10-2018 DFR85_13620 c9d1262aab134781dabdf524e1f1b1d4 90 Gene3D G3DSA:1.10.10.10 2 89 1.6E-22 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_13620 c9d1262aab134781dabdf524e1f1b1d4 90 Pfam PF14947 Winged helix-turn-helix 3 76 1.8E-21 T 31-10-2018 IPR038723 ArnR1-like, winged helix-turn-helix domain DFR85_13620 c9d1262aab134781dabdf524e1f1b1d4 90 SUPERFAMILY SSF46785 4 80 1.53E-11 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_11445 6363433d30a756f92d0018eddcbd6e9d 230 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 109 120 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR85_11445 6363433d30a756f92d0018eddcbd6e9d 230 SUPERFAMILY SSF46548 60 140 2.79E-15 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 DFR85_11445 6363433d30a756f92d0018eddcbd6e9d 230 Pfam PF13183 4Fe-4S dicluster domain 62 123 1.9E-8 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR85_11445 6363433d30a756f92d0018eddcbd6e9d 230 Gene3D G3DSA:1.10.1060.10 28 142 2.1E-11 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 DFR85_11980 f1255f3613f7e92398d6177d105172ad 371 SUPERFAMILY SSF103473 6 368 2.22E-49 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_11980 f1255f3613f7e92398d6177d105172ad 371 Pfam PF07690 Major Facilitator Superfamily 12 333 2.7E-33 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_11980 f1255f3613f7e92398d6177d105172ad 371 Gene3D G3DSA:1.20.1250.20 186 371 4.7E-14 T 31-10-2018 DFR85_11980 f1255f3613f7e92398d6177d105172ad 371 Gene3D G3DSA:1.20.1250.20 4 185 9.0E-27 T 31-10-2018 DFR85_01640 cebb43a715ae198691ca81a1b4338608 134 Pfam PF00581 Rhodanese-like domain 22 107 7.2E-13 T 31-10-2018 IPR001763 Rhodanese-like domain DFR85_01640 cebb43a715ae198691ca81a1b4338608 134 ProSitePatterns PS00380 Rhodanese signature 1. 43 54 - T 31-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 DFR85_01640 cebb43a715ae198691ca81a1b4338608 134 SMART SM00450 18 112 1.7E-17 T 31-10-2018 IPR001763 Rhodanese-like domain DFR85_01640 cebb43a715ae198691ca81a1b4338608 134 Gene3D G3DSA:3.40.250.10 22 132 1.2E-20 T 31-10-2018 IPR036873 Rhodanese-like domain superfamily DFR85_01640 cebb43a715ae198691ca81a1b4338608 134 SUPERFAMILY SSF52821 11 118 4.19E-25 T 31-10-2018 IPR036873 Rhodanese-like domain superfamily DFR85_13535 1ef7ae49d3d2c6541120fba0521261ec 173 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 2 57 6.4E-16 T 31-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 DFR85_13535 1ef7ae49d3d2c6541120fba0521261ec 173 TIGRFAM TIGR01527 arch_NMN_Atrans: nicotinamide-nucleotide adenylyltransferase 2 165 2.0E-57 T 31-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 DFR85_13535 1ef7ae49d3d2c6541120fba0521261ec 173 SUPERFAMILY SSF52374 1 158 1.84E-31 T 31-10-2018 DFR85_13535 1ef7ae49d3d2c6541120fba0521261ec 173 Hamap MF_00243 Nicotinamide-nucleotide adenylyltransferase. 1 173 71.179 T 31-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 DFR85_13535 1ef7ae49d3d2c6541120fba0521261ec 173 Pfam PF01467 Cytidylyltransferase-like 4 132 2.9E-18 T 31-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 DFR85_13535 1ef7ae49d3d2c6541120fba0521261ec 173 Gene3D G3DSA:3.40.50.620 1 171 3.7E-45 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR85_04475 0f2a8c2b36888814b956a75f387760ea 583 Gene3D G3DSA:1.20.1740.10 6 463 2.0E-65 T 31-10-2018 DFR85_04475 0f2a8c2b36888814b956a75f387760ea 583 Pfam PF13520 Amino acid permease 12 443 5.0E-45 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_11110 c0549a81cd16006702ab43c7b7d6573a 217 SUPERFAMILY SSF52540 4 186 3.84E-18 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_11110 c0549a81cd16006702ab43c7b7d6573a 217 Gene3D G3DSA:3.40.50.300 4 210 4.9E-16 T 31-10-2018 DFR85_11110 c0549a81cd16006702ab43c7b7d6573a 217 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 188 4.7E-10 T 31-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain DFR85_02505 097aa1217e1828bc94ef337570c8dafa 388 Gene3D G3DSA:1.20.1250.20 6 190 3.5E-13 T 31-10-2018 DFR85_02505 097aa1217e1828bc94ef337570c8dafa 388 Gene3D G3DSA:1.20.1250.20 268 387 4.9E-7 T 31-10-2018 DFR85_02505 097aa1217e1828bc94ef337570c8dafa 388 Pfam PF07690 Major Facilitator Superfamily 13 322 7.4E-20 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_02505 097aa1217e1828bc94ef337570c8dafa 388 SUPERFAMILY SSF103473 11 384 3.27E-33 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_15775 c7913cb4ffb47a06ac8d720c68a33a81 200 Pfam PF07185 Protein of unknown function (DUF1404) 11 196 1.5E-39 T 31-10-2018 IPR009844 Protein of unknown function DUF1404 DFR85_10020 edca6eadb29050bbef9f31053dcbe85e 322 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 30 41 - T 31-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 DFR85_10020 edca6eadb29050bbef9f31053dcbe85e 322 Pfam PF04055 Radical SAM superfamily 29 138 7.0E-12 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR85_10020 edca6eadb29050bbef9f31053dcbe85e 322 SUPERFAMILY SSF102114 23 283 1.06E-37 T 31-10-2018 DFR85_10020 edca6eadb29050bbef9f31053dcbe85e 322 Gene3D G3DSA:3.20.20.70 21 293 2.8E-32 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_10020 edca6eadb29050bbef9f31053dcbe85e 322 Pfam PF13353 4Fe-4S single cluster domain 24 125 6.7E-9 T 31-10-2018 DFR85_15800 803ebc910f3a50b64cb65fedd3cb746f 197 Gene3D G3DSA:2.60.40.2600 58 184 1.4E-22 T 31-10-2018 DFR85_15800 803ebc910f3a50b64cb65fedd3cb746f 197 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 82 153 3.1E-7 T 31-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_15800 803ebc910f3a50b64cb65fedd3cb746f 197 SUPERFAMILY SSF49503 56 169 3.55E-22 T 31-10-2018 IPR008972 Cupredoxin DFR85_13640 99129cc899bd61e026414c7b3d684559 353 Pfam PF02371 Transposase IS116/IS110/IS902 family 232 317 7.0E-24 T 31-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 DFR85_08455 1837115b8f036fed026a4282e732d21b 203 SUPERFAMILY SSF52141 2 181 2.13E-63 T 31-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 DFR85_08455 1837115b8f036fed026a4282e732d21b 203 Pfam PF03167 Uracil DNA glycosylase superfamily 27 171 4.1E-47 T 31-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 DFR85_08455 1837115b8f036fed026a4282e732d21b 203 SMART SM00987 27 177 6.1E-38 T 31-10-2018 DFR85_08455 1837115b8f036fed026a4282e732d21b 203 SMART SM00986 27 177 6.1E-38 T 31-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 DFR85_08455 1837115b8f036fed026a4282e732d21b 203 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 13 181 3.0E-70 T 31-10-2018 IPR005273 Uracil-DNA glycosylase family 4 DFR85_08455 1837115b8f036fed026a4282e732d21b 203 Gene3D G3DSA:3.40.470.10 1 183 5.7E-70 T 31-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 DFR85_10625 accaf61190a7f819ab548dace35c4d52 394 SUPERFAMILY SSF53686 2 373 2.88E-107 T 31-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme DFR85_10625 accaf61190a7f819ab548dace35c4d52 394 PIRSF PIRSF038945 32 388 1.3E-132 T 31-10-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 DFR85_10625 accaf61190a7f819ab548dace35c4d52 394 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 84 97 - T 31-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 DFR85_10625 accaf61190a7f819ab548dace35c4d52 394 TIGRFAM TIGR00260 thrC: threonine synthase 45 365 5.0E-88 T 31-10-2018 IPR004450 Threonine synthase-like DFR85_10625 accaf61190a7f819ab548dace35c4d52 394 Gene3D G3DSA:3.40.50.1100 47 364 4.3E-118 T 31-10-2018 DFR85_10625 accaf61190a7f819ab548dace35c4d52 394 Gene3D G3DSA:3.40.50.1100 92 189 4.3E-118 T 31-10-2018 DFR85_10625 accaf61190a7f819ab548dace35c4d52 394 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 61 358 1.2E-74 T 31-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme DFR85_06650 3a314528f69fb1960482e8b76a618a61 186 SUPERFAMILY SSF81301 19 146 1.73E-6 T 31-10-2018 DFR85_06650 3a314528f69fb1960482e8b76a618a61 186 Pfam PF09970 Nucleotidyl transferase of unknown function (DUF2204) 3 180 1.3E-57 T 31-10-2018 IPR018700 Protein of unknown function DUF2204 DFR85_04620 9a35e921111758c2f5d0ba59730d9b4e 349 SUPERFAMILY SSF52540 3 273 5.05E-45 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_04620 9a35e921111758c2f5d0ba59730d9b4e 349 Pfam PF01637 ATPase domain predominantly from Archaea 14 242 4.0E-19 T 31-10-2018 IPR011579 ATPase domain GO:0005524 DFR85_04620 9a35e921111758c2f5d0ba59730d9b4e 349 Gene3D G3DSA:1.10.8.60 203 276 5.3E-19 T 31-10-2018 DFR85_04620 9a35e921111758c2f5d0ba59730d9b4e 349 Gene3D G3DSA:3.40.50.300 1 201 1.3E-47 T 31-10-2018 DFR85_04620 9a35e921111758c2f5d0ba59730d9b4e 349 Gene3D G3DSA:1.10.10.10 280 346 3.1E-13 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_04620 9a35e921111758c2f5d0ba59730d9b4e 349 SUPERFAMILY SSF46785 279 343 2.12E-14 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_14145 347cc70f92514213e4449a04456d66e9 375 Gene3D G3DSA:1.10.10.2140 317 367 1.2E-18 T 31-10-2018 DFR85_14145 347cc70f92514213e4449a04456d66e9 375 TIGRFAM TIGR00075 hypD: hydrogenase expression/formation protein HypD 10 365 2.1E-119 T 31-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 DFR85_14145 347cc70f92514213e4449a04456d66e9 375 PIRSF PIRSF005622 5 370 6.8E-118 T 31-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 DFR85_14145 347cc70f92514213e4449a04456d66e9 375 Gene3D G3DSA:3.40.50.11740 66 299 5.8E-95 T 31-10-2018 DFR85_14145 347cc70f92514213e4449a04456d66e9 375 Pfam PF01924 Hydrogenase formation hypA family 17 363 8.7E-121 T 31-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 DFR85_14145 347cc70f92514213e4449a04456d66e9 375 Gene3D G3DSA:3.40.50.11750 23 259 5.8E-95 T 31-10-2018 DFR85_01145 6df5f4e8d2ea6324dafb043182fccf95 474 Gene3D G3DSA:3.30.300.30 373 472 1.2E-11 T 31-10-2018 DFR85_01145 6df5f4e8d2ea6324dafb043182fccf95 474 Pfam PF14535 AMP-binding enzyme C-terminal domain 378 470 2.3E-12 T 31-10-2018 IPR028154 AMP-dependent ligase, C-terminal DFR85_01145 6df5f4e8d2ea6324dafb043182fccf95 474 Gene3D G3DSA:3.40.50.12780 26 370 7.5E-62 T 31-10-2018 DFR85_01145 6df5f4e8d2ea6324dafb043182fccf95 474 SUPERFAMILY SSF56801 82 435 1.05E-20 T 31-10-2018 DFR85_01465 0a10dcd65319a60f25179447d021d3c3 229 SUPERFAMILY SSF56784 7 216 5.32E-36 T 31-10-2018 IPR036412 HAD-like superfamily DFR85_01465 0a10dcd65319a60f25179447d021d3c3 229 TIGRFAM TIGR01487 Pglycolate_arch: phosphoglycolate phosphatase, TA0175-type 6 215 7.6E-49 T 31-10-2018 DFR85_01465 0a10dcd65319a60f25179447d021d3c3 229 Gene3D G3DSA:3.90.1070.10 83 145 1.8E-38 T 31-10-2018 DFR85_01465 0a10dcd65319a60f25179447d021d3c3 229 Pfam PF08282 haloacid dehalogenase-like hydrolase 118 214 6.6E-19 T 31-10-2018 DFR85_01465 0a10dcd65319a60f25179447d021d3c3 229 Pfam PF08282 haloacid dehalogenase-like hydrolase 8 83 6.1E-7 T 31-10-2018 DFR85_01465 0a10dcd65319a60f25179447d021d3c3 229 Gene3D G3DSA:3.40.50.1000 7 213 1.8E-38 T 31-10-2018 IPR023214 HAD superfamily DFR85_01465 0a10dcd65319a60f25179447d021d3c3 229 TIGRFAM TIGR01482 SPP-subfamily: sucrose-phosphate phosphatase subfamily 8 218 1.9E-41 T 31-10-2018 DFR85_06685 7f24ae0bfdfab8774a5269ec663ff61e 91 Hamap MF_00043 Elongation factor 1-beta [ef1b]. 1 91 41.68 T 31-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 DFR85_06685 7f24ae0bfdfab8774a5269ec663ff61e 91 Pfam PF00736 EF-1 guanine nucleotide exchange domain 6 89 1.3E-16 T 31-10-2018 IPR014038 Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain GO:0003746|GO:0006414 Reactome: R-HSA-156842 DFR85_06685 7f24ae0bfdfab8774a5269ec663ff61e 91 PIRSF PIRSF006521 1 89 1.1E-31 T 31-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 DFR85_06685 7f24ae0bfdfab8774a5269ec663ff61e 91 SUPERFAMILY SSF54984 1 89 4.97E-24 T 31-10-2018 IPR036219 Translation elongation factor eEF-1beta-like superfamily Reactome: R-HSA-156842 DFR85_06685 7f24ae0bfdfab8774a5269ec663ff61e 91 TIGRFAM TIGR00489 aEF-1_beta: translation elongation factor aEF-1 beta 1 89 4.5E-22 T 31-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 DFR85_06685 7f24ae0bfdfab8774a5269ec663ff61e 91 SMART SM00888 3 89 1.5E-38 T 31-10-2018 IPR014038 Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain GO:0003746|GO:0006414 Reactome: R-HSA-156842 DFR85_06685 7f24ae0bfdfab8774a5269ec663ff61e 91 Gene3D G3DSA:3.30.70.60 1 89 2.5E-27 T 31-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 DFR85_02865 a360abcb1c1b5f73b3766753ebbd2479 348 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 5 315 9.5E-56 T 31-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 DFR85_02865 a360abcb1c1b5f73b3766753ebbd2479 348 Pfam PF01180 Dihydroorotate dehydrogenase 5 300 2.8E-32 T 31-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 DFR85_02865 a360abcb1c1b5f73b3766753ebbd2479 348 SUPERFAMILY SSF51395 1 316 1.5E-66 T 31-10-2018 DFR85_02865 a360abcb1c1b5f73b3766753ebbd2479 348 Gene3D G3DSA:3.20.20.70 4 306 2.1E-92 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_02865 a360abcb1c1b5f73b3766753ebbd2479 348 PIRSF PIRSF000164 1 317 4.6E-87 T 31-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 DFR85_13935 ce8fca739542ad93135526740b47519c 300 SMART SM00382 27 210 2.0E-5 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_13935 ce8fca739542ad93135526740b47519c 300 Gene3D G3DSA:3.40.50.300 1 236 4.0E-55 T 31-10-2018 DFR85_13935 ce8fca739542ad93135526740b47519c 300 SUPERFAMILY SSF52540 2 222 6.74E-53 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_13935 ce8fca739542ad93135526740b47519c 300 Pfam PF00005 ABC transporter 18 161 2.7E-25 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR85_13935 ce8fca739542ad93135526740b47519c 300 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DFR85_00925 91b64a31f1db89a4cc4d9b6e0f129462 349 Gene3D G3DSA:1.10.150.20 167 233 6.0E-21 T 31-10-2018 DFR85_00925 91b64a31f1db89a4cc4d9b6e0f129462 349 Gene3D G3DSA:3.30.70.270 75 166 3.2E-30 T 31-10-2018 DFR85_00925 91b64a31f1db89a4cc4d9b6e0f129462 349 Gene3D G3DSA:2.30.40.20 11 74 4.7E-28 T 31-10-2018 DFR85_00925 91b64a31f1db89a4cc4d9b6e0f129462 349 SUPERFAMILY SSF56672 3 239 5.34E-67 T 31-10-2018 DFR85_00925 91b64a31f1db89a4cc4d9b6e0f129462 349 Pfam PF00817 impB/mucB/samB family 7 155 1.7E-42 T 31-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 DFR85_00925 91b64a31f1db89a4cc4d9b6e0f129462 349 Hamap MF_01113 DNA polymerase IV [dinB]. 1 347 28.441 T 31-10-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 DFR85_00925 91b64a31f1db89a4cc4d9b6e0f129462 349 Gene3D G3DSA:3.30.1490.100 243 340 2.5E-24 T 31-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 DFR85_00925 91b64a31f1db89a4cc4d9b6e0f129462 349 SUPERFAMILY SSF100879 240 341 3.73E-24 T 31-10-2018 IPR036775 DNA polymerase, Y-family, little finger domain superfamily GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 DFR85_00925 91b64a31f1db89a4cc4d9b6e0f129462 349 Pfam PF11798 IMS family HHH motif 169 199 7.0E-8 T 31-10-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 DFR85_05275 3b5eb63c5b6e4573907eaf10ba90d184 589 SUPERFAMILY SSF54631 472 569 1.21E-19 T 31-10-2018 DFR85_05275 3b5eb63c5b6e4573907eaf10ba90d184 589 PRINTS PR00762 Chloride channel signature 379 395 9.8E-17 T 31-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 DFR85_05275 3b5eb63c5b6e4573907eaf10ba90d184 589 PRINTS PR00762 Chloride channel signature 397 416 9.8E-17 T 31-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 DFR85_05275 3b5eb63c5b6e4573907eaf10ba90d184 589 PRINTS PR00762 Chloride channel signature 121 140 9.8E-17 T 31-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 DFR85_05275 3b5eb63c5b6e4573907eaf10ba90d184 589 PRINTS PR00762 Chloride channel signature 172 191 9.8E-17 T 31-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 DFR85_05275 3b5eb63c5b6e4573907eaf10ba90d184 589 PRINTS PR00762 Chloride channel signature 344 364 9.8E-17 T 31-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 DFR85_05275 3b5eb63c5b6e4573907eaf10ba90d184 589 Gene3D G3DSA:3.10.580.10 469 583 6.8E-17 T 31-10-2018 DFR85_05275 3b5eb63c5b6e4573907eaf10ba90d184 589 Gene3D G3DSA:1.10.3080.10 7 453 3.4E-83 T 31-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 DFR85_05275 3b5eb63c5b6e4573907eaf10ba90d184 589 Pfam PF00654 Voltage gated chloride channel 78 428 3.1E-76 T 31-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 DFR85_05275 3b5eb63c5b6e4573907eaf10ba90d184 589 SMART SM00116 469 515 0.63 T 31-10-2018 IPR000644 CBS domain DFR85_05275 3b5eb63c5b6e4573907eaf10ba90d184 589 SMART SM00116 524 571 1.6E-4 T 31-10-2018 IPR000644 CBS domain DFR85_05275 3b5eb63c5b6e4573907eaf10ba90d184 589 SUPERFAMILY SSF81340 5 446 1.83E-87 T 31-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 DFR85_05275 3b5eb63c5b6e4573907eaf10ba90d184 589 Pfam PF00571 CBS domain 524 568 4.1E-6 T 31-10-2018 IPR000644 CBS domain DFR85_05275 3b5eb63c5b6e4573907eaf10ba90d184 589 Pfam PF00571 CBS domain 470 512 4.9E-7 T 31-10-2018 IPR000644 CBS domain DFR85_03765 99ee5f2f775c91402e60474499a6cb70 184 Gene3D G3DSA:1.25.40.10 57 167 7.7E-19 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 DFR85_03765 99ee5f2f775c91402e60474499a6cb70 184 Pfam PF13414 TPR repeat 42 73 3.4E-7 T 31-10-2018 DFR85_03765 99ee5f2f775c91402e60474499a6cb70 184 Pfam PF13414 TPR repeat 106 130 1.4E-8 T 31-10-2018 DFR85_03765 99ee5f2f775c91402e60474499a6cb70 184 Gene3D G3DSA:1.25.40.10 8 56 1.4E-6 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 DFR85_03765 99ee5f2f775c91402e60474499a6cb70 184 SUPERFAMILY SSF48452 16 175 3.32E-27 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 DFR85_03765 99ee5f2f775c91402e60474499a6cb70 184 SMART SM00028 26 58 14.0 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 DFR85_03765 99ee5f2f775c91402e60474499a6cb70 184 SMART SM00028 94 127 2.2E-6 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 DFR85_03765 99ee5f2f775c91402e60474499a6cb70 184 SMART SM00028 59 92 0.0016 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 DFR85_10140 2ca62bb269fce21a9c8514da09bdfb5c 223 Pfam PF01912 eIF-6 family 5 203 5.5E-66 T 31-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 DFR85_10140 2ca62bb269fce21a9c8514da09bdfb5c 223 TIGRFAM TIGR00323 eIF-6: putative translation initiation factor eIF-6 7 222 5.3E-54 T 31-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 DFR85_10140 2ca62bb269fce21a9c8514da09bdfb5c 223 SUPERFAMILY SSF55909 3 222 1.18E-65 T 31-10-2018 DFR85_10140 2ca62bb269fce21a9c8514da09bdfb5c 223 Gene3D G3DSA:3.75.10.10 1 222 4.4E-71 T 31-10-2018 DFR85_10140 2ca62bb269fce21a9c8514da09bdfb5c 223 PIRSF PIRSF006413 2 223 3.1E-76 T 31-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 DFR85_10140 2ca62bb269fce21a9c8514da09bdfb5c 223 SMART SM00654 4 203 2.0E-89 T 31-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 DFR85_10140 2ca62bb269fce21a9c8514da09bdfb5c 223 Hamap MF_00032 Translation initiation factor 6 [eif6]. 1 223 82.709 T 31-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 DFR85_07035 b8364fd8094a323da06ca8351d0cdbd8 54 Gene3D G3DSA:4.10.830.10 4 54 7.8E-19 T 31-10-2018 DFR85_07035 b8364fd8094a323da06ca8351d0cdbd8 54 Pfam PF00253 Ribosomal protein S14p/S29e 6 52 6.2E-9 T 31-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_07035 b8364fd8094a323da06ca8351d0cdbd8 54 Hamap MF_01364_A 30S ribosomal protein S14 type Z [rpsZ]. 2 54 16.059 T 31-10-2018 IPR023676 Ribosomal protein S14, type Z, archaeal GO:0003723|GO:0003735|GO:0006412|GO:0015935 DFR85_07035 b8364fd8094a323da06ca8351d0cdbd8 54 ProSitePatterns PS00527 Ribosomal protein S14 signature. 21 42 - T 31-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_11670 a9eff182fe08e317a91e06169f0f9a8e 280 Gene3D G3DSA:3.10.580.10 1 133 5.2E-33 T 31-10-2018 DFR85_11670 a9eff182fe08e317a91e06169f0f9a8e 280 SUPERFAMILY SSF54631 72 191 2.64E-35 T 31-10-2018 DFR85_11670 a9eff182fe08e317a91e06169f0f9a8e 280 SMART SM00116 146 194 7.1E-10 T 31-10-2018 IPR000644 CBS domain DFR85_11670 a9eff182fe08e317a91e06169f0f9a8e 280 SMART SM00116 83 131 5.6E-13 T 31-10-2018 IPR000644 CBS domain DFR85_11670 a9eff182fe08e317a91e06169f0f9a8e 280 SMART SM00116 217 265 1.3E-9 T 31-10-2018 IPR000644 CBS domain DFR85_11670 a9eff182fe08e317a91e06169f0f9a8e 280 SMART SM00116 10 56 0.16 T 31-10-2018 IPR000644 CBS domain DFR85_11670 a9eff182fe08e317a91e06169f0f9a8e 280 SUPERFAMILY SSF54631 3 57 2.92E-5 T 31-10-2018 DFR85_11670 a9eff182fe08e317a91e06169f0f9a8e 280 Pfam PF00571 CBS domain 76 130 6.8E-16 T 31-10-2018 IPR000644 CBS domain DFR85_11670 a9eff182fe08e317a91e06169f0f9a8e 280 Pfam PF00571 CBS domain 210 265 6.3E-14 T 31-10-2018 IPR000644 CBS domain DFR85_11670 a9eff182fe08e317a91e06169f0f9a8e 280 Pfam PF00571 CBS domain 140 190 2.3E-11 T 31-10-2018 IPR000644 CBS domain DFR85_11670 a9eff182fe08e317a91e06169f0f9a8e 280 Pfam PF00571 CBS domain 10 54 4.6E-5 T 31-10-2018 IPR000644 CBS domain DFR85_11670 a9eff182fe08e317a91e06169f0f9a8e 280 Gene3D G3DSA:3.10.580.10 134 273 4.6E-47 T 31-10-2018 DFR85_11670 a9eff182fe08e317a91e06169f0f9a8e 280 SUPERFAMILY SSF54631 206 266 6.75E-15 T 31-10-2018 DFR85_12745 a6f8d508c8a41bff69c7ed014bd4d709 262 Pfam PF10040 CRISPR-associated endoribonuclease Cas6 130 254 1.2E-18 T 31-10-2018 IPR019267 CRISPR-associated protein Cas6, C-terminal DFR85_12745 a6f8d508c8a41bff69c7ed014bd4d709 262 Gene3D G3DSA:3.30.70.1900 112 262 9.8E-39 T 31-10-2018 DFR85_12745 a6f8d508c8a41bff69c7ed014bd4d709 262 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 43 255 9.0E-35 T 31-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 DFR85_04810 4c7ddd23b0f8704141a0159072e69124 409 Pfam PF13635 Domain of unknown function (DUF4143) 217 352 1.3E-9 T 31-10-2018 IPR025420 Domain of unknown function DUF4143 DFR85_04810 4c7ddd23b0f8704141a0159072e69124 409 Pfam PF13173 AAA domain 42 162 5.3E-32 T 31-10-2018 DFR85_04810 4c7ddd23b0f8704141a0159072e69124 409 SUPERFAMILY SSF52540 25 220 6.45E-22 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_09130 bc078e4e70f5117b62e57a302e595a9e 141 PIRSF PIRSF006276 1 141 4.5E-18 T 31-10-2018 IPR006015 Universal stress protein A DFR85_09130 bc078e4e70f5117b62e57a302e595a9e 141 SUPERFAMILY SSF52402 2 141 2.09E-38 T 31-10-2018 DFR85_09130 bc078e4e70f5117b62e57a302e595a9e 141 PRINTS PR01438 Universal stress protein signature 2 20 1.6E-19 T 31-10-2018 IPR006015 Universal stress protein A DFR85_09130 bc078e4e70f5117b62e57a302e595a9e 141 PRINTS PR01438 Universal stress protein signature 101 113 1.6E-19 T 31-10-2018 IPR006015 Universal stress protein A DFR85_09130 bc078e4e70f5117b62e57a302e595a9e 141 PRINTS PR01438 Universal stress protein signature 119 141 1.6E-19 T 31-10-2018 IPR006015 Universal stress protein A DFR85_09130 bc078e4e70f5117b62e57a302e595a9e 141 Gene3D G3DSA:3.40.50.620 1 141 4.0E-41 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR85_09130 bc078e4e70f5117b62e57a302e595a9e 141 Pfam PF00582 Universal stress protein family 1 141 1.4E-36 T 31-10-2018 IPR006016 UspA DFR85_14060 e5684f60258f0d1b5a563bca36890352 418 Pfam PF00202 Aminotransferase class-III 24 411 7.6E-114 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DFR85_14060 e5684f60258f0d1b5a563bca36890352 418 Gene3D G3DSA:3.40.640.10 59 318 6.1E-135 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR85_14060 e5684f60258f0d1b5a563bca36890352 418 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 239 276 - T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DFR85_14060 e5684f60258f0d1b5a563bca36890352 418 PIRSF PIRSF000521 9 129 9.3E-9 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DFR85_14060 e5684f60258f0d1b5a563bca36890352 418 PIRSF PIRSF000521 124 417 8.2E-41 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DFR85_14060 e5684f60258f0d1b5a563bca36890352 418 SUPERFAMILY SSF53383 16 416 1.91E-121 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase DFR85_14060 e5684f60258f0d1b5a563bca36890352 418 Gene3D G3DSA:3.90.1150.10 4 411 6.1E-135 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 DFR85_08350 302a21fe5dbd8616582f5ff5a0c89e2c 441 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 45 149 1.9E-14 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 DFR85_08350 302a21fe5dbd8616582f5ff5a0c89e2c 441 SMART SM00382 41 164 8.5E-10 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_08350 302a21fe5dbd8616582f5ff5a0c89e2c 441 Hamap MF_01508 Replication factor C large subunit [rfcL]. 4 431 32.896 T 31-10-2018 IPR023935 Replication factor C, large subunit DFR85_08350 302a21fe5dbd8616582f5ff5a0c89e2c 441 Gene3D G3DSA:1.10.8.60 166 226 1.1E-15 T 31-10-2018 DFR85_08350 302a21fe5dbd8616582f5ff5a0c89e2c 441 Gene3D G3DSA:3.40.50.300 5 162 6.0E-38 T 31-10-2018 DFR85_08350 302a21fe5dbd8616582f5ff5a0c89e2c 441 SUPERFAMILY SSF52540 4 227 2.37E-43 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_05895 9de5be3ff06fc9cad3b6e15207f27fff 537 Gene3D G3DSA:1.10.3720.10 5 208 5.7E-13 T 31-10-2018 IPR035906 MetI-like superfamily DFR85_05895 9de5be3ff06fc9cad3b6e15207f27fff 537 Gene3D G3DSA:1.10.3720.10 317 520 5.9E-17 T 31-10-2018 IPR035906 MetI-like superfamily DFR85_05895 9de5be3ff06fc9cad3b6e15207f27fff 537 SUPERFAMILY SSF161098 324 511 3.53E-16 T 31-10-2018 IPR035906 MetI-like superfamily DFR85_05895 9de5be3ff06fc9cad3b6e15207f27fff 537 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 26 211 2.0E-8 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 DFR85_05895 9de5be3ff06fc9cad3b6e15207f27fff 537 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 335 522 8.0E-13 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 DFR85_05895 9de5be3ff06fc9cad3b6e15207f27fff 537 SUPERFAMILY SSF161098 9 203 6.15E-14 T 31-10-2018 IPR035906 MetI-like superfamily DFR85_01680 c4f8b2d69f24a2cac42706453afd5f03 779 Gene3D G3DSA:1.25.50.20 504 777 3.2E-27 T 31-10-2018 DFR85_01680 c4f8b2d69f24a2cac42706453afd5f03 779 Gene3D G3DSA:2.60.40.1910 420 496 1.4E-19 T 31-10-2018 DFR85_01680 c4f8b2d69f24a2cac42706453afd5f03 779 SUPERFAMILY SSF55486 182 425 7.47E-83 T 31-10-2018 DFR85_01680 c4f8b2d69f24a2cac42706453afd5f03 779 SUPERFAMILY SSF63737 3 171 3.79E-42 T 31-10-2018 DFR85_01680 c4f8b2d69f24a2cac42706453afd5f03 779 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 231 241 4.3E-26 T 31-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DFR85_01680 c4f8b2d69f24a2cac42706453afd5f03 779 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 108 123 4.3E-26 T 31-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DFR85_01680 c4f8b2d69f24a2cac42706453afd5f03 779 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 285 297 4.3E-26 T 31-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DFR85_01680 c4f8b2d69f24a2cac42706453afd5f03 779 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 155 170 4.3E-26 T 31-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DFR85_01680 c4f8b2d69f24a2cac42706453afd5f03 779 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 266 281 4.3E-26 T 31-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DFR85_01680 c4f8b2d69f24a2cac42706453afd5f03 779 Gene3D G3DSA:1.10.390.60 180 419 3.0E-94 T 31-10-2018 DFR85_01680 c4f8b2d69f24a2cac42706453afd5f03 779 Gene3D G3DSA:2.60.40.1730 1 173 1.2E-45 T 31-10-2018 DFR85_01680 c4f8b2d69f24a2cac42706453afd5f03 779 Pfam PF11838 ERAP1-like C-terminal domain 482 773 1.8E-32 T 31-10-2018 IPR024571 ERAP1-like C-terminal domain DFR85_01680 c4f8b2d69f24a2cac42706453afd5f03 779 Pfam PF01433 Peptidase family M1 domain 186 414 9.3E-85 T 31-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 DFR85_02795 a42d30a852ec53277518967f3bd4614f 494 PIRSF PIRSF006060 1 486 3.1E-53 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_02795 a42d30a852ec53277518967f3bd4614f 494 Pfam PF00324 Amino acid permease 27 455 9.2E-28 T 31-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 DFR85_02795 a42d30a852ec53277518967f3bd4614f 494 Gene3D G3DSA:1.20.1740.10 17 463 2.3E-28 T 31-10-2018 DFR85_14025 77f6e0468431e129a3d1d144f6d795e7 104 Pfam PF13601 Winged helix DNA-binding domain 22 100 9.5E-18 T 31-10-2018 IPR027395 Winged helix DNA-binding domain DFR85_14025 77f6e0468431e129a3d1d144f6d795e7 104 Gene3D G3DSA:1.10.10.10 5 102 1.8E-22 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_14025 77f6e0468431e129a3d1d144f6d795e7 104 SUPERFAMILY SSF46785 15 100 1.34E-15 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_14800 246bd3b19a137af389379beb773e4c19 391 SUPERFAMILY SSF53383 6 388 7.03E-98 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase DFR85_14800 246bd3b19a137af389379beb773e4c19 391 Gene3D G3DSA:3.90.1150.10 257 391 2.2E-49 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 DFR85_14800 246bd3b19a137af389379beb773e4c19 391 Gene3D G3DSA:3.40.640.10 6 256 2.3E-73 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR85_14800 246bd3b19a137af389379beb773e4c19 391 PIRSF PIRSF001434 2 391 4.8E-135 T 31-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 DFR85_14800 246bd3b19a137af389379beb773e4c19 391 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 9 388 2.0E-126 T 31-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 DFR85_14800 246bd3b19a137af389379beb773e4c19 391 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 198 212 - T 31-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 DFR85_02620 0917b89a9fa0e0dd407750b754f8b882 401 Pfam PF01385 Probable transposase 181 287 4.4E-20 T 31-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 DFR85_02620 0917b89a9fa0e0dd407750b754f8b882 401 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 255 330 3.3E-15 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR85_02620 0917b89a9fa0e0dd407750b754f8b882 401 Pfam PF07282 Putative transposase DNA-binding domain 305 372 1.3E-23 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR85_14090 4524f0adcb1de9402c9584987d54cfd3 75 Pfam PF01455 HupF/HypC family 1 63 3.4E-14 T 31-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC DFR85_14090 4524f0adcb1de9402c9584987d54cfd3 75 Gene3D G3DSA:2.40.50.970 1 74 3.1E-16 T 31-10-2018 IPR037254 HupF/HypC superfamily DFR85_14090 4524f0adcb1de9402c9584987d54cfd3 75 SUPERFAMILY SSF159127 1 74 9.68E-17 T 31-10-2018 IPR037254 HupF/HypC superfamily DFR85_14445 f254c66932c55753fa7306b851cdc79d 144 ProSitePatterns PS00893 Nudix box signature. 40 61 - T 31-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 DFR85_14445 f254c66932c55753fa7306b851cdc79d 144 SUPERFAMILY SSF55811 3 133 3.11E-23 T 31-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 DFR85_14445 f254c66932c55753fa7306b851cdc79d 144 Pfam PF00293 NUDIX domain 9 119 5.3E-16 T 31-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 DFR85_14445 f254c66932c55753fa7306b851cdc79d 144 Gene3D G3DSA:3.90.79.10 6 131 2.1E-24 T 31-10-2018 DFR85_10595 dc0fe2a1949454b197062a9a5ad838db 358 PIRSF PIRSF015578 1 358 9.8E-94 T 31-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 DFR85_10595 dc0fe2a1949454b197062a9a5ad838db 358 Pfam PF01658 Myo-inositol-1-phosphate synthase 191 301 2.4E-29 T 31-10-2018 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 DFR85_10595 dc0fe2a1949454b197062a9a5ad838db 358 Gene3D G3DSA:3.40.50.720 2 346 4.2E-105 T 31-10-2018 DFR85_10595 dc0fe2a1949454b197062a9a5ad838db 358 SUPERFAMILY SSF51735 2 355 5.91E-79 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_10595 dc0fe2a1949454b197062a9a5ad838db 358 SUPERFAMILY SSF55347 189 301 7.06E-30 T 31-10-2018 DFR85_10595 dc0fe2a1949454b197062a9a5ad838db 358 Gene3D G3DSA:3.30.360.10 190 302 4.2E-105 T 31-10-2018 DFR85_00950 b4e19cb62b744aa631d413bce75325eb 243 Pfam PF13531 Bacterial extracellular solute-binding protein 96 237 2.5E-8 T 31-10-2018 DFR85_00950 b4e19cb62b744aa631d413bce75325eb 243 SUPERFAMILY SSF53850 94 237 5.18E-14 T 31-10-2018 DFR85_02675 17eba86b7bbd14fd5b0bd07e970e0a1f 229 Pfam PF02633 Creatinine amidohydrolase 12 222 3.4E-43 T 31-10-2018 IPR003785 Creatininase/formamide hydrolase KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 DFR85_02675 17eba86b7bbd14fd5b0bd07e970e0a1f 229 Gene3D G3DSA:3.40.50.10310 1 228 9.5E-42 T 31-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 DFR85_02675 17eba86b7bbd14fd5b0bd07e970e0a1f 229 SUPERFAMILY SSF102215 1 227 2.35E-49 T 31-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 DFR85_14830 1bc44ba3fec289554c686cefd23674ad 392 Pfam PF07690 Major Facilitator Superfamily 19 317 1.2E-16 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_14830 1bc44ba3fec289554c686cefd23674ad 392 Gene3D G3DSA:1.20.1250.20 6 193 5.7E-16 T 31-10-2018 DFR85_14830 1bc44ba3fec289554c686cefd23674ad 392 Gene3D G3DSA:1.20.1250.20 207 390 1.3E-7 T 31-10-2018 DFR85_14830 1bc44ba3fec289554c686cefd23674ad 392 SUPERFAMILY SSF103473 11 389 2.35E-30 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_09155 206fad89733ed8bde82a3b96175546c6 308 Gene3D G3DSA:3.40.50.720 5 301 8.8E-95 T 31-10-2018 DFR85_09155 206fad89733ed8bde82a3b96175546c6 308 SUPERFAMILY SSF51735 1 150 1.36E-20 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_09155 206fad89733ed8bde82a3b96175546c6 308 SUPERFAMILY SSF55347 141 288 1.31E-41 T 31-10-2018 DFR85_09155 206fad89733ed8bde82a3b96175546c6 308 Pfam PF00742 Homoserine dehydrogenase 136 301 6.4E-48 T 31-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 DFR85_09155 206fad89733ed8bde82a3b96175546c6 308 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 174 196 - T 31-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 DFR85_09155 206fad89733ed8bde82a3b96175546c6 308 PIRSF PIRSF036497 1 307 1.6E-82 T 31-10-2018 IPR022697 Homoserine dehydrogenase lacking ACT domain GO:0004412 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 DFR85_09155 206fad89733ed8bde82a3b96175546c6 308 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 7 120 4.9E-11 T 31-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 DFR85_09155 206fad89733ed8bde82a3b96175546c6 308 Gene3D G3DSA:3.30.360.10 140 284 8.8E-95 T 31-10-2018 DFR85_01355 96ecd1dced4d82e20f7680fdcfe83d27 288 SUPERFAMILY SSF53850 3 286 2.42E-46 T 31-10-2018 DFR85_01355 96ecd1dced4d82e20f7680fdcfe83d27 288 Pfam PF02621 Menaquinone biosynthesis 4 275 1.3E-58 T 31-10-2018 IPR003773 Menaquinone biosynthesis enzyme DFR85_01355 96ecd1dced4d82e20f7680fdcfe83d27 288 Gene3D G3DSA:3.40.190.10 110 288 6.0E-20 T 31-10-2018 DFR85_01355 96ecd1dced4d82e20f7680fdcfe83d27 288 Gene3D G3DSA:3.40.190.10 1 104 2.3E-6 T 31-10-2018 DFR85_11330 91ee377d6cbe3b9dd555f53b543c787f 316 Gene3D G3DSA:3.30.230.10 1 169 8.5E-25 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup DFR85_11330 91ee377d6cbe3b9dd555f53b543c787f 316 Pfam PF00288 GHMP kinases N terminal domain 91 149 5.3E-13 T 31-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 DFR85_11330 91ee377d6cbe3b9dd555f53b543c787f 316 PRINTS PR00960 LmbP protein signature 264 283 4.7E-5 T 31-10-2018 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0016301 KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 DFR85_11330 91ee377d6cbe3b9dd555f53b543c787f 316 PRINTS PR00960 LmbP protein signature 87 108 4.7E-5 T 31-10-2018 IPR001174 Galactokinase/homoserine kinase GO:0005524|GO:0016301 KEGG: 00540+2.7.1.168|MetaCyc: PWY-6478 DFR85_11330 91ee377d6cbe3b9dd555f53b543c787f 316 SUPERFAMILY SSF54211 2 186 1.29E-35 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold DFR85_11330 91ee377d6cbe3b9dd555f53b543c787f 316 SUPERFAMILY SSF55060 173 305 3.12E-14 T 31-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily DFR85_11330 91ee377d6cbe3b9dd555f53b543c787f 316 Pfam PF08544 GHMP kinases C terminal 252 296 2.9E-5 T 31-10-2018 IPR013750 GHMP kinase, C-terminal domain DFR85_11330 91ee377d6cbe3b9dd555f53b543c787f 316 Gene3D G3DSA:3.30.70.890 171 305 5.2E-12 T 31-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily DFR85_03925 7d0cfe84cedfa53625ee48306570ecdd 147 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 1 137 5.3E-25 T 31-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 DFR85_03925 7d0cfe84cedfa53625ee48306570ecdd 147 Gene3D G3DSA:2.20.28.10 74 127 1.5E-17 T 31-10-2018 DFR85_03925 7d0cfe84cedfa53625ee48306570ecdd 147 Hamap MF_00213 Hydrogenase maturation factor HypA [hypA]. 1 138 18.448 T 31-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 DFR85_03925 7d0cfe84cedfa53625ee48306570ecdd 147 Gene3D G3DSA:3.30.2320.50 1 73 6.7E-16 T 31-10-2018 DFR85_03925 7d0cfe84cedfa53625ee48306570ecdd 147 PIRSF PIRSF004761 1 141 5.4E-33 T 31-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 DFR85_02975 81e11942576a3b263ce171a6c2cbc64d 397 SUPERFAMILY SSF103473 12 390 8.89E-58 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_02975 81e11942576a3b263ce171a6c2cbc64d 397 Gene3D G3DSA:1.20.1250.20 208 396 5.3E-20 T 31-10-2018 DFR85_02975 81e11942576a3b263ce171a6c2cbc64d 397 Pfam PF07690 Major Facilitator Superfamily 30 251 3.0E-26 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_02975 81e11942576a3b263ce171a6c2cbc64d 397 Gene3D G3DSA:1.20.1250.20 10 200 3.3E-27 T 31-10-2018 DFR85_10555 9be5d7b5d6a5ab4927e48b637207bbad 248 Gene3D G3DSA:3.20.20.70 1 248 1.1E-94 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_10555 9be5d7b5d6a5ab4927e48b637207bbad 248 Pfam PF00218 Indole-3-glycerol phosphate synthase 10 242 5.8E-74 T 31-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 DFR85_10555 9be5d7b5d6a5ab4927e48b637207bbad 248 Hamap MF_00134_A Indole-3-glycerol phosphate synthase [trpC]. 30 248 35.576 T 31-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 DFR85_10555 9be5d7b5d6a5ab4927e48b637207bbad 248 SUPERFAMILY SSF51366 27 241 4.4E-65 T 31-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 DFR85_07095 61badba71b81fc409c9ea2c1d1d30fd7 83 Gene3D G3DSA:3.30.70.330 1 83 9.0E-31 T 31-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily DFR85_07095 61badba71b81fc409c9ea2c1d1d30fd7 83 SUPERFAMILY SSF54189 1 76 2.52E-22 T 31-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_07095 61badba71b81fc409c9ea2c1d1d30fd7 83 ProSitePatterns PS00050 Ribosomal protein L23 signature. 61 76 - T 31-10-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07095 61badba71b81fc409c9ea2c1d1d30fd7 83 Pfam PF00276 Ribosomal protein L23 3 64 4.6E-14 T 31-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 DFR85_07095 61badba71b81fc409c9ea2c1d1d30fd7 83 Hamap MF_01369_A 50S ribosomal protein L23 [rplW]. 3 83 22.876 T 31-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 DFR85_07095 61badba71b81fc409c9ea2c1d1d30fd7 83 TIGRFAM TIGR03636 uL23_arch: ribosomal protein uL23 7 83 5.9E-31 T 31-10-2018 IPR019985 Ribosomal protein L23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07385 5d217770f2328c770e9e92f661f2279b 238 Pfam PF09754 PAC2 family 18 220 1.1E-32 T 31-10-2018 IPR019151 Proteasome assembly chaperone 2 DFR85_07385 5d217770f2328c770e9e92f661f2279b 238 Gene3D G3DSA:3.40.50.10900 2 236 1.1E-39 T 31-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily DFR85_07385 5d217770f2328c770e9e92f661f2279b 238 SUPERFAMILY SSF159659 7 229 3.66E-32 T 31-10-2018 DFR85_14715 0aeac776969b2ed2d1871a8fd4581fa2 77 SUPERFAMILY SSF64307 6 77 1.31E-9 T 31-10-2018 IPR036868 TusA-like domain superfamily DFR85_14715 0aeac776969b2ed2d1871a8fd4581fa2 77 Gene3D G3DSA:3.30.110.40 5 77 1.2E-10 T 31-10-2018 IPR036868 TusA-like domain superfamily DFR85_14715 0aeac776969b2ed2d1871a8fd4581fa2 77 Pfam PF01206 Sulfurtransferase TusA 8 76 1.9E-10 T 31-10-2018 IPR001455 TusA-like domain DFR85_04870 be7f569c44d5738efc495a3c5ac3c986 298 Pfam PF03787 RAMP superfamily 100 269 6.9E-6 T 31-10-2018 IPR005537 CRISPR type III-associated RAMP protein DFR85_04870 be7f569c44d5738efc495a3c5ac3c986 298 TIGRFAM TIGR01898 cas_TM1791_cmr6: CRISPR type III-B/RAMP module RAMP protein Cmr6 70 270 1.1E-29 T 31-10-2018 IPR010172 CRISPR-associated protein, TM1791 DFR85_02380 4aa9794c0faff4244bdf03005573732d 236 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 3 194 9.2E-34 T 31-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase DFR85_02380 4aa9794c0faff4244bdf03005573732d 236 Gene3D G3DSA:3.40.50.10420 31 202 2.0E-14 T 31-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily DFR85_02380 4aa9794c0faff4244bdf03005573732d 236 SUPERFAMILY SSF100950 1 211 5.02E-33 T 31-10-2018 IPR037171 NagB/RpiA transferase-like DFR85_11070 4cf1de6453aa91eeeee71b7490ee60e6 459 SUPERFAMILY SSF103473 9 451 3.4E-57 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_11070 4cf1de6453aa91eeeee71b7490ee60e6 459 Pfam PF00083 Sugar (and other) transporter 47 450 1.6E-53 T 31-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 DFR85_11070 4cf1de6453aa91eeeee71b7490ee60e6 459 ProSitePatterns PS00217 Sugar transport proteins signature 2. 123 148 - T 31-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DFR85_13515 0fe62816453ed602aa5c3c87034fdf02 753 Gene3D G3DSA:3.30.70.2230 476 619 2.6E-5 T 31-10-2018 DFR85_13515 0fe62816453ed602aa5c3c87034fdf02 753 SUPERFAMILY SSF109604 92 170 6.0E-6 T 31-10-2018 DFR85_09025 2dd5c1bb040e6226baa84493b0b7a90a 293 SUPERFAMILY SSF53448 4 275 4.36E-21 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_09025 2dd5c1bb040e6226baa84493b0b7a90a 293 Gene3D G3DSA:3.90.550.10 4 195 1.3E-13 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_09025 2dd5c1bb040e6226baa84493b0b7a90a 293 Pfam PF00535 Glycosyl transferase family 2 17 124 6.6E-9 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 DFR85_10395 b7c1276b9c145901f5fbb2fc7d013d70 42 SUPERFAMILY SSF47598 1 40 1.78E-6 T 31-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 DFR85_10395 b7c1276b9c145901f5fbb2fc7d013d70 42 Gene3D G3DSA:1.10.1220.10 2 41 4.2E-6 T 31-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 DFR85_10395 b7c1276b9c145901f5fbb2fc7d013d70 42 Pfam PF01402 Ribbon-helix-helix protein, copG family 4 40 4.8E-8 T 31-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 DFR85_04015 c7bfdb14e29b66173587409fe7bf07ed 126 Pfam PF01909 Nucleotidyltransferase domain 3 68 4.2E-12 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 DFR85_04015 c7bfdb14e29b66173587409fe7bf07ed 126 SUPERFAMILY SSF81301 6 105 1.52E-15 T 31-10-2018 DFR85_04015 c7bfdb14e29b66173587409fe7bf07ed 126 Gene3D G3DSA:3.30.460.10 1 92 5.2E-13 T 31-10-2018 DFR85_08560 0aca7a9fd0f7a27f9dec20f448401ee1 307 SUPERFAMILY SSF159664 182 303 1.31E-15 T 31-10-2018 IPR036518 CobE/GbiG C-terminal domain superfamily GO:0009236 DFR85_08560 0aca7a9fd0f7a27f9dec20f448401ee1 307 Pfam PF01890 Cobalamin synthesis G C-terminus 193 303 7.2E-11 T 31-10-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 DFR85_08560 0aca7a9fd0f7a27f9dec20f448401ee1 307 SUPERFAMILY SSF159672 11 195 2.75E-29 T 31-10-2018 IPR038029 GbiG N-terminal domain superfamily KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 DFR85_08560 0aca7a9fd0f7a27f9dec20f448401ee1 307 Gene3D G3DSA:3.30.420.180 183 304 1.4E-10 T 31-10-2018 IPR036518 CobE/GbiG C-terminal domain superfamily GO:0009236 DFR85_08560 0aca7a9fd0f7a27f9dec20f448401ee1 307 Pfam PF11760 Cobalamin synthesis G N-terminal 36 106 2.4E-13 T 31-10-2018 IPR021744 Cobalamin synthesis G, N-terminal KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 DFR85_08560 0aca7a9fd0f7a27f9dec20f448401ee1 307 Gene3D G3DSA:3.40.50.11220 3 102 4.8E-14 T 31-10-2018 DFR85_02065 d63794ba9cb2daf74ddc28f76c96b961 205 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 97 199 3.7E-19 T 31-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_02065 d63794ba9cb2daf74ddc28f76c96b961 205 SUPERFAMILY SSF56770 77 201 2.22E-42 T 31-10-2018 DFR85_02065 d63794ba9cb2daf74ddc28f76c96b961 205 Gene3D G3DSA:3.40.50.12280 68 205 6.0E-37 T 31-10-2018 DFR85_11550 32fbdc8dd119949560a03ebc757fcec9 470 Gene3D G3DSA:1.20.1720.10 6 241 2.6E-47 T 31-10-2018 DFR85_11550 32fbdc8dd119949560a03ebc757fcec9 470 Pfam PF07690 Major Facilitator Superfamily 11 399 2.2E-51 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_11550 32fbdc8dd119949560a03ebc757fcec9 470 SUPERFAMILY SSF103473 4 460 3.66E-65 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_11550 32fbdc8dd119949560a03ebc757fcec9 470 Gene3D G3DSA:1.20.1250.20 248 466 8.9E-18 T 31-10-2018 DFR85_01400 a2cd97233bced8da09e2585dfb705c91 333 Gene3D G3DSA:3.50.50.60 125 243 4.5E-93 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_01400 a2cd97233bced8da09e2585dfb705c91 333 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 297 1.6E-32 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR85_01400 a2cd97233bced8da09e2585dfb705c91 333 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 284 1.2E-21 T 31-10-2018 DFR85_01400 a2cd97233bced8da09e2585dfb705c91 333 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 153 171 1.2E-21 T 31-10-2018 DFR85_01400 a2cd97233bced8da09e2585dfb705c91 333 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 236 252 1.2E-21 T 31-10-2018 DFR85_01400 a2cd97233bced8da09e2585dfb705c91 333 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.2E-21 T 31-10-2018 DFR85_01400 a2cd97233bced8da09e2585dfb705c91 333 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 5 27 9.8E-24 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR85_01400 a2cd97233bced8da09e2585dfb705c91 333 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 110 118 9.8E-24 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR85_01400 a2cd97233bced8da09e2585dfb705c91 333 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 149 173 9.8E-24 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR85_01400 a2cd97233bced8da09e2585dfb705c91 333 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 272 290 9.8E-24 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR85_01400 a2cd97233bced8da09e2585dfb705c91 333 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 199 215 9.8E-24 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 DFR85_01400 a2cd97233bced8da09e2585dfb705c91 333 Hamap MF_01685 Ferredoxin--NADP reductase. 3 327 39.818 T 31-10-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 DFR85_01400 a2cd97233bced8da09e2585dfb705c91 333 Gene3D G3DSA:3.50.50.60 5 305 4.5E-93 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_01400 a2cd97233bced8da09e2585dfb705c91 333 SUPERFAMILY SSF51905 1 303 3.29E-44 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_04460 bcdc24f0bdb9f861cb418323c79a352d 77 Hamap MF_01245 UPF0248 protein . 7 75 16.363 T 31-10-2018 IPR007547 Uncharacterised protein family UPF0248 DFR85_04460 bcdc24f0bdb9f861cb418323c79a352d 77 Pfam PF04457 Protein of unknown function (DUF504) 23 74 1.9E-16 T 31-10-2018 IPR007547 Uncharacterised protein family UPF0248 DFR85_13065 7cff100825308c4ecb7dc09abfd6cd32 95 Pfam PF01909 Nucleotidyltransferase domain 20 55 3.6E-8 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 DFR85_13065 7cff100825308c4ecb7dc09abfd6cd32 95 SUPERFAMILY SSF81301 9 57 2.73E-10 T 31-10-2018 DFR85_13065 7cff100825308c4ecb7dc09abfd6cd32 95 Gene3D G3DSA:3.30.460.10 1 67 4.7E-10 T 31-10-2018 DFR85_05540 4ab20eee3d7984ec9481a79fc6fdd038 310 SUPERFAMILY SSF50182 125 209 1.44E-11 T 31-10-2018 IPR010920 LSM domain superfamily DFR85_05540 4ab20eee3d7984ec9481a79fc6fdd038 310 Pfam PF00924 Mechanosensitive ion channel 83 275 2.5E-28 T 31-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 DFR85_05540 4ab20eee3d7984ec9481a79fc6fdd038 310 Gene3D G3DSA:2.30.30.60 170 210 2.7E-5 T 31-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily DFR85_08160 c884073732407860cf1650f77ad640fa 175 Gene3D G3DSA:1.20.1540.10 1 174 2.1E-16 T 31-10-2018 IPR035952 Rhomboid-like superfamily DFR85_08160 c884073732407860cf1650f77ad640fa 175 SUPERFAMILY SSF144091 7 173 4.58E-24 T 31-10-2018 DFR85_08160 c884073732407860cf1650f77ad640fa 175 Pfam PF01694 Rhomboid family 34 167 1.4E-14 T 31-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 DFR85_08825 a98f9f0460d65c89863ec6de55685f22 175 Gene3D G3DSA:3.40.630.30 2 142 1.7E-37 T 31-10-2018 DFR85_08825 a98f9f0460d65c89863ec6de55685f22 175 Pfam PF06557 Protein of unknown function (DUF1122) 15 165 2.3E-53 T 31-10-2018 IPR008304 Uncharacterised conserved protein UCP017998 DFR85_08825 a98f9f0460d65c89863ec6de55685f22 175 SUPERFAMILY SSF55729 6 166 7.31E-51 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase DFR85_10785 cd38976acd1646e59508da2df74e664a 93 Gene3D G3DSA:2.40.10.230 2 81 1.0E-11 T 31-10-2018 IPR038664 H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain DFR85_10785 cd38976acd1646e59508da2df74e664a 93 SUPERFAMILY SSF50447 9 71 2.61E-8 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily DFR85_07900 bef8e6bf030c62e3617e2905b0733eff 245 Gene3D G3DSA:3.70.10.10 1 244 4.6E-70 T 31-10-2018 DFR85_07900 bef8e6bf030c62e3617e2905b0733eff 245 Pfam PF00705 Proliferating cell nuclear antigen, N-terminal domain 9 98 2.0E-14 T 31-10-2018 IPR022648 Proliferating cell nuclear antigen, PCNA, N-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 DFR85_07900 bef8e6bf030c62e3617e2905b0733eff 245 SUPERFAMILY SSF55979 2 123 2.93E-27 T 31-10-2018 DFR85_07900 bef8e6bf030c62e3617e2905b0733eff 245 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 55 79 6.7E-13 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 DFR85_07900 bef8e6bf030c62e3617e2905b0733eff 245 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 192 206 6.7E-13 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 DFR85_07900 bef8e6bf030c62e3617e2905b0733eff 245 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 230 245 6.7E-13 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 DFR85_07900 bef8e6bf030c62e3617e2905b0733eff 245 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 33 51 6.7E-13 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 DFR85_07900 bef8e6bf030c62e3617e2905b0733eff 245 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 9 28 6.7E-13 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 DFR85_07900 bef8e6bf030c62e3617e2905b0733eff 245 TIGRFAM TIGR00590 pcna: proliferating cell nuclear antigen (pcna) 9 244 2.2E-34 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 DFR85_07900 bef8e6bf030c62e3617e2905b0733eff 245 ProSitePatterns PS01251 Proliferating cell nuclear antigen signature 1. 33 56 - T 31-10-2018 IPR022659 Proliferating cell nuclear antigen, PCNA, conserved site Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 DFR85_07900 bef8e6bf030c62e3617e2905b0733eff 245 Hamap MF_00317 DNA polymerase sliding clamp [pcn]. 1 244 27.734 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 DFR85_07900 bef8e6bf030c62e3617e2905b0733eff 245 Pfam PF02747 Proliferating cell nuclear antigen, C-terminal domain 126 242 2.1E-13 T 31-10-2018 IPR022649 Proliferating cell nuclear antigen, PCNA, C-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 DFR85_07900 bef8e6bf030c62e3617e2905b0733eff 245 SUPERFAMILY SSF55979 125 244 8.38E-26 T 31-10-2018 DFR85_10040 f85597d90c691589f5832ddc4e090329 452 Pfam PF00501 AMP-binding enzyme 10 374 9.4E-56 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 DFR85_10040 f85597d90c691589f5832ddc4e090329 452 Gene3D G3DSA:3.30.300.30 370 451 1.6E-11 T 31-10-2018 DFR85_10040 f85597d90c691589f5832ddc4e090329 452 SUPERFAMILY SSF56801 2 451 5.63E-78 T 31-10-2018 DFR85_10040 f85597d90c691589f5832ddc4e090329 452 Pfam PF13193 AMP-binding enzyme C-terminal domain 384 451 7.0E-8 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain DFR85_10040 f85597d90c691589f5832ddc4e090329 452 Gene3D G3DSA:3.40.50.12780 1 369 1.4E-65 T 31-10-2018 DFR85_15400 f1967449f70aaff0025b79888630be28 431 Gene3D G3DSA:3.30.300.30 336 430 1.1E-18 T 31-10-2018 DFR85_15400 f1967449f70aaff0025b79888630be28 431 Gene3D G3DSA:3.40.50.12780 4 335 2.8E-110 T 31-10-2018 DFR85_15400 f1967449f70aaff0025b79888630be28 431 Pfam PF14535 AMP-binding enzyme C-terminal domain 344 428 3.3E-14 T 31-10-2018 IPR028154 AMP-dependent ligase, C-terminal DFR85_15400 f1967449f70aaff0025b79888630be28 431 Pfam PF00501 AMP-binding enzyme 87 297 1.7E-14 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 DFR85_15400 f1967449f70aaff0025b79888630be28 431 SUPERFAMILY SSF56801 33 401 4.84E-54 T 31-10-2018 DFR85_13600 e40d6867ad5fa89974cf846c0311b98b 1300 SMART SM00944 42 173 1.6E-33 T 31-10-2018 IPR015366 Peptidase S53, activation domain GO:0008236 Reactome: R-HSA-381038 DFR85_13600 e40d6867ad5fa89974cf846c0311b98b 1300 Gene3D G3DSA:2.60.40.10 1135 1242 2.4E-7 T 31-10-2018 IPR013783 Immunoglobulin-like fold DFR85_13600 e40d6867ad5fa89974cf846c0311b98b 1300 Gene3D G3DSA:3.40.50.200 203 569 9.8E-77 T 31-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 DFR85_13600 e40d6867ad5fa89974cf846c0311b98b 1300 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 486 496 - T 31-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site DFR85_13600 e40d6867ad5fa89974cf846c0311b98b 1300 SUPERFAMILY SSF52743 213 565 4.19E-66 T 31-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 DFR85_13600 e40d6867ad5fa89974cf846c0311b98b 1300 SUPERFAMILY SSF54897 33 168 1.09E-18 T 31-10-2018 DFR85_13600 e40d6867ad5fa89974cf846c0311b98b 1300 Pfam PF00082 Subtilase family 320 504 1.4E-5 T 31-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 DFR85_13600 e40d6867ad5fa89974cf846c0311b98b 1300 PIRSF PIRSF032623 2 1300 0.0 T 31-10-2018 IPR017001 Peptidase S53, physarolisin II, archaeal-type DFR85_13600 e40d6867ad5fa89974cf846c0311b98b 1300 Pfam PF09286 Pro-kumamolisin, activation domain 44 166 7.8E-21 T 31-10-2018 IPR015366 Peptidase S53, activation domain GO:0008236 Reactome: R-HSA-381038 DFR85_01900 f1104c47ecb21aeaaa70cb48c01bef4e 374 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 278 362 1.9E-5 T 31-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 DFR85_01900 f1104c47ecb21aeaaa70cb48c01bef4e 374 Gene3D G3DSA:3.30.160.100 273 369 3.2E-6 T 31-10-2018 IPR036567 Ribosome hibernation promotion factor-like DFR85_01900 f1104c47ecb21aeaaa70cb48c01bef4e 374 SUPERFAMILY SSF54631 3 118 5.56E-17 T 31-10-2018 DFR85_01900 f1104c47ecb21aeaaa70cb48c01bef4e 374 Pfam PF00571 CBS domain 11 55 5.8E-5 T 31-10-2018 IPR000644 CBS domain DFR85_01900 f1104c47ecb21aeaaa70cb48c01bef4e 374 Pfam PF00571 CBS domain 68 117 2.5E-4 T 31-10-2018 IPR000644 CBS domain DFR85_01900 f1104c47ecb21aeaaa70cb48c01bef4e 374 Pfam PF00571 CBS domain 127 180 1.2E-9 T 31-10-2018 IPR000644 CBS domain DFR85_01900 f1104c47ecb21aeaaa70cb48c01bef4e 374 Pfam PF00571 CBS domain 203 256 4.1E-6 T 31-10-2018 IPR000644 CBS domain DFR85_01900 f1104c47ecb21aeaaa70cb48c01bef4e 374 PIRSF PIRSF036983 1 373 2.4E-96 T 31-10-2018 IPR014651 Uncharacterised conserved protein, 2xCBS, MJ1404 type DFR85_01900 f1104c47ecb21aeaaa70cb48c01bef4e 374 SUPERFAMILY SSF69754 274 368 4.71E-11 T 31-10-2018 IPR036567 Ribosome hibernation promotion factor-like DFR85_01900 f1104c47ecb21aeaaa70cb48c01bef4e 374 SUPERFAMILY SSF54631 124 256 1.06E-25 T 31-10-2018 DFR85_01900 f1104c47ecb21aeaaa70cb48c01bef4e 374 Gene3D G3DSA:3.10.580.10 121 257 8.3E-24 T 31-10-2018 DFR85_01900 f1104c47ecb21aeaaa70cb48c01bef4e 374 SMART SM00116 10 57 0.01 T 31-10-2018 IPR000644 CBS domain DFR85_01900 f1104c47ecb21aeaaa70cb48c01bef4e 374 SMART SM00116 69 117 0.0041 T 31-10-2018 IPR000644 CBS domain DFR85_01900 f1104c47ecb21aeaaa70cb48c01bef4e 374 SMART SM00116 210 257 0.0018 T 31-10-2018 IPR000644 CBS domain DFR85_01900 f1104c47ecb21aeaaa70cb48c01bef4e 374 SMART SM00116 134 181 0.0019 T 31-10-2018 IPR000644 CBS domain DFR85_01900 f1104c47ecb21aeaaa70cb48c01bef4e 374 Gene3D G3DSA:3.10.580.10 3 120 3.0E-15 T 31-10-2018 DFR85_03290 1507908099996c86dcd050b11574efbe 394 Pfam PF04894 Archaeal Nre, N-terminal 15 277 3.3E-95 T 31-10-2018 IPR006978 Archaeal Nre, N-terminal DFR85_03290 1507908099996c86dcd050b11574efbe 394 Hamap MF_02096 DNA repair protein. 1 392 33.437 T 31-10-2018 IPR033167 Archaeal Nre GO:0006281 DFR85_03290 1507908099996c86dcd050b11574efbe 394 Pfam PF04895 Archaeal Nre, C-terminal 290 387 1.2E-29 T 31-10-2018 IPR006979 Archaeal Nre, C-terminal DFR85_09575 f0670ad4aa81cba9970336807ea43241 101 Gene3D G3DSA:1.20.120.610 5 99 2.9E-12 T 31-10-2018 DFR85_09575 f0670ad4aa81cba9970336807ea43241 101 SUPERFAMILY SSF81333 36 99 4.97E-11 T 31-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily DFR85_09575 f0670ad4aa81cba9970336807ea43241 101 Pfam PF00137 ATP synthase subunit C 37 96 1.7E-12 T 31-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 DFR85_09575 f0670ad4aa81cba9970336807ea43241 101 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 48 74 8.7E-7 T 31-10-2018 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 DFR85_09575 f0670ad4aa81cba9970336807ea43241 101 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 75 98 8.7E-7 T 31-10-2018 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 DFR85_15460 d26e1acd99f1b9384ef6b4adc6d3aa2c 366 Pfam PF02515 CoA-transferase family III 3 308 2.5E-68 T 31-10-2018 IPR003673 CoA-transferase family III GO:0003824 DFR85_15460 d26e1acd99f1b9384ef6b4adc6d3aa2c 366 Gene3D G3DSA:3.40.50.10540 2 208 2.1E-51 T 31-10-2018 IPR023606 CoA-transferase family III domain superfamily DFR85_15460 d26e1acd99f1b9384ef6b4adc6d3aa2c 366 Gene3D G3DSA:3.40.50.10540 295 365 1.2E-5 T 31-10-2018 IPR023606 CoA-transferase family III domain superfamily DFR85_15460 d26e1acd99f1b9384ef6b4adc6d3aa2c 366 Gene3D G3DSA:3.30.1540.10 209 294 5.8E-16 T 31-10-2018 DFR85_15460 d26e1acd99f1b9384ef6b4adc6d3aa2c 366 SUPERFAMILY SSF89796 3 362 1.83E-81 T 31-10-2018 IPR023606 CoA-transferase family III domain superfamily DFR85_08510 0f15f1f1a15109a058589bfe69818884 372 SMART SM00933 62 341 2.8E-14 T 31-10-2018 IPR018977 NurA domain DFR85_08510 0f15f1f1a15109a058589bfe69818884 372 Pfam PF09376 NurA domain 63 340 5.2E-17 T 31-10-2018 IPR018977 NurA domain DFR85_07365 43a6b1fef0d85f6bc1080c14cf37b52b 354 Gene3D G3DSA:3.40.50.300 178 354 6.9E-43 T 31-10-2018 DFR85_07365 43a6b1fef0d85f6bc1080c14cf37b52b 354 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 12 311 2.0E-65 T 31-10-2018 IPR016496 GTPase HflX GO:0005525 DFR85_07365 43a6b1fef0d85f6bc1080c14cf37b52b 354 Pfam PF16360 GTP-binding GTPase Middle Region 96 171 2.6E-17 T 31-10-2018 IPR032305 GTP-binding protein, middle domain DFR85_07365 43a6b1fef0d85f6bc1080c14cf37b52b 354 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 180 340 6.6E-15 T 31-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 DFR85_07365 43a6b1fef0d85f6bc1080c14cf37b52b 354 Gene3D G3DSA:3.40.50.11060 1 96 8.2E-31 T 31-10-2018 DFR85_07365 43a6b1fef0d85f6bc1080c14cf37b52b 354 PIRSF PIRSF006809 3 353 6.5E-88 T 31-10-2018 IPR016496 GTPase HflX GO:0005525 DFR85_07365 43a6b1fef0d85f6bc1080c14cf37b52b 354 Pfam PF13167 GTP-binding GTPase N-terminal 13 94 9.5E-10 T 31-10-2018 IPR025121 GTPase HflX, N-terminal DFR85_07365 43a6b1fef0d85f6bc1080c14cf37b52b 354 Pfam PF01926 50S ribosome-binding GTPase 181 300 8.0E-19 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 DFR85_07365 43a6b1fef0d85f6bc1080c14cf37b52b 354 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 202 220 2.9E-5 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 DFR85_07365 43a6b1fef0d85f6bc1080c14cf37b52b 354 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 247 265 2.9E-5 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 DFR85_07365 43a6b1fef0d85f6bc1080c14cf37b52b 354 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 181 201 2.9E-5 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 DFR85_07365 43a6b1fef0d85f6bc1080c14cf37b52b 354 SUPERFAMILY SSF52540 178 352 2.49E-35 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_05715 0c4654b5535e7259dc866876c7af02b8 316 SUPERFAMILY SSF52540 123 220 9.15E-9 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_05715 0c4654b5535e7259dc866876c7af02b8 316 Gene3D G3DSA:3.40.50.300 139 255 2.5E-8 T 31-10-2018 DFR85_05715 0c4654b5535e7259dc866876c7af02b8 316 Pfam PF01935 Domain of unknown function DUF87 153 239 1.1E-10 T 31-10-2018 IPR002789 Helicase HerA, central domain DFR85_12525 4b04ffa7f1d763ec7796e56f8609b893 302 Gene3D G3DSA:3.30.110.40 122 192 1.9E-6 T 31-10-2018 IPR036868 TusA-like domain superfamily DFR85_12525 4b04ffa7f1d763ec7796e56f8609b893 302 SUPERFAMILY SSF64307 115 192 1.23E-10 T 31-10-2018 IPR036868 TusA-like domain superfamily DFR85_15250 6ad10f7629a1de35ee29ad80802092b0 298 PIRSF PIRSF032676 1 298 1.2E-150 T 31-10-2018 IPR017004 Uncharacterised conserved protein UCP032676, PqqC DFR85_15250 6ad10f7629a1de35ee29ad80802092b0 298 Gene3D G3DSA:1.20.910.10 1 298 3.6E-124 T 31-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 DFR85_15250 6ad10f7629a1de35ee29ad80802092b0 298 Pfam PF16293 C2H2 type zinc-finger (1 copy) 1 59 5.6E-22 T 31-10-2018 IPR032553 UCP032676, C2H2 type zinc-finger domain DFR85_15250 6ad10f7629a1de35ee29ad80802092b0 298 Pfam PF03070 TENA/THI-4/PQQC family 70 283 2.7E-43 T 31-10-2018 IPR004305 Thiaminase-2/PQQC DFR85_15250 6ad10f7629a1de35ee29ad80802092b0 298 SUPERFAMILY SSF48613 73 279 2.35E-41 T 31-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 DFR85_15240 1dbae188c225c1226687e531fb4615ff 291 SUPERFAMILY SSF47240 249 289 7.03E-6 T 31-10-2018 IPR009078 Ferritin-like superfamily DFR85_15240 1dbae188c225c1226687e531fb4615ff 291 Pfam PF13478 XdhC Rossmann domain 111 231 7.9E-22 T 31-10-2018 IPR027051 XdhC Rossmann domain DFR85_15240 1dbae188c225c1226687e531fb4615ff 291 Pfam PF02625 XdhC and CoxI family 25 86 1.5E-10 T 31-10-2018 IPR003777 XdhC- CoxI DFR85_15240 1dbae188c225c1226687e531fb4615ff 291 SMART SM00746 249 286 1.2E-6 T 31-10-2018 IPR011017 TRASH domain DFR85_15240 1dbae188c225c1226687e531fb4615ff 291 Pfam PF04945 YHS domain 249 290 3.5E-11 T 31-10-2018 IPR007029 YHS domain DFR85_15240 1dbae188c225c1226687e531fb4615ff 291 Gene3D G3DSA:3.40.50.720 139 252 1.6E-22 T 31-10-2018 DFR85_06355 6284ae642b66a070b4ff3a0b68f81428 229 SUPERFAMILY SSF56281 1 229 1.13E-39 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR85_06355 6284ae642b66a070b4ff3a0b68f81428 229 SMART SM00849 19 201 6.5E-11 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR85_06355 6284ae642b66a070b4ff3a0b68f81428 229 Gene3D G3DSA:3.60.15.10 1 229 8.2E-43 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR85_06355 6284ae642b66a070b4ff3a0b68f81428 229 Pfam PF12706 Beta-lactamase superfamily domain 51 201 4.3E-13 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR85_15305 a0c50ee5c357691087191d30ba6b47c4 131 Gene3D G3DSA:3.10.129.10 1 130 3.3E-28 T 31-10-2018 DFR85_15305 a0c50ee5c357691087191d30ba6b47c4 131 Pfam PF03061 Thioesterase superfamily 47 121 1.7E-14 T 31-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 DFR85_15305 a0c50ee5c357691087191d30ba6b47c4 131 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 16 128 4.7E-21 T 31-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 DFR85_15305 a0c50ee5c357691087191d30ba6b47c4 131 SUPERFAMILY SSF54637 16 130 4.27E-26 T 31-10-2018 IPR029069 HotDog domain superfamily DFR85_13970 2c19530fbe3181ef7eec09ed2d2705f9 105 Pfam PF07849 Protein of unknown function (DUF1641) 68 100 2.1E-6 T 31-10-2018 IPR012440 Protein of unknown function DUF1641 DFR85_00660 8d1dad54332502cf9d069a0fcc2a9fdc 172 SUPERFAMILY SSF50324 3 168 9.16E-66 T 31-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 DFR85_00660 8d1dad54332502cf9d069a0fcc2a9fdc 172 Gene3D G3DSA:3.90.80.10 1 171 2.3E-69 T 31-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 DFR85_00660 8d1dad54332502cf9d069a0fcc2a9fdc 172 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 11 170 38.391 T 31-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 DFR85_00660 8d1dad54332502cf9d069a0fcc2a9fdc 172 Pfam PF00719 Inorganic pyrophosphatase 15 168 2.0E-56 T 31-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 DFR85_00660 8d1dad54332502cf9d069a0fcc2a9fdc 172 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 62 68 - T 31-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 DFR85_07180 7dd0498f4a66c44f24fbf7081b8e1616 242 Pfam PF15985 KH domain 151 198 7.9E-8 T 31-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 DFR85_07180 7dd0498f4a66c44f24fbf7081b8e1616 242 Hamap MF_00623 Exosome complex component Rrp4 [rrp4]. 9 234 37.343 T 31-10-2018 IPR023474 Exosome complex component Rrp4 GO:0000178|GO:0008143 DFR85_07180 7dd0498f4a66c44f24fbf7081b8e1616 242 SUPERFAMILY SSF110324 5 62 1.1E-13 T 31-10-2018 DFR85_07180 7dd0498f4a66c44f24fbf7081b8e1616 242 SUPERFAMILY SSF50249 64 154 1.33E-19 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR85_07180 7dd0498f4a66c44f24fbf7081b8e1616 242 Gene3D G3DSA:2.40.50.140 63 149 1.6E-20 T 31-10-2018 DFR85_07180 7dd0498f4a66c44f24fbf7081b8e1616 242 Gene3D G3DSA:2.40.50.100 1 61 6.7E-25 T 31-10-2018 DFR85_07180 7dd0498f4a66c44f24fbf7081b8e1616 242 SMART SM00316 68 141 3.3E-5 T 31-10-2018 IPR022967 RNA-binding domain, S1 DFR85_07180 7dd0498f4a66c44f24fbf7081b8e1616 242 SUPERFAMILY SSF54791 150 230 3.86E-17 T 31-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 DFR85_07180 7dd0498f4a66c44f24fbf7081b8e1616 242 Gene3D G3DSA:3.30.1370.10 151 242 7.3E-35 T 31-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 DFR85_11045 edc9e8bb5a06a3ca5c443dd4a1b5a574 92 SUPERFAMILY SSF56176 12 81 2.06E-9 T 31-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 DFR85_11045 edc9e8bb5a06a3ca5c443dd4a1b5a574 92 Gene3D G3DSA:3.30.43.10 1 85 2.4E-10 T 31-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 DFR85_11045 edc9e8bb5a06a3ca5c443dd4a1b5a574 92 Pfam PF01565 FAD binding domain 40 80 1.1E-5 T 31-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 DFR85_03375 108ff7a896f18778b34f489cc78c0966 175 Pfam PF04173 TQO small subunit DoxD 13 175 8.0E-58 T 31-10-2018 IPR007301 TQO small subunit DoxD KEGG: 00920+1.8.5.2|MetaCyc: PWY-5303 DFR85_11065 a4461a6b459fa0a81507febfb31b5f57 218 Gene3D G3DSA:1.10.150.660 16 92 6.0E-73 T 31-10-2018 DFR85_11065 a4461a6b459fa0a81507febfb31b5f57 218 SUPERFAMILY SSF56784 2 215 7.59E-28 T 31-10-2018 IPR036412 HAD-like superfamily DFR85_11065 a4461a6b459fa0a81507febfb31b5f57 218 Gene3D G3DSA:3.40.50.1000 5 210 6.0E-73 T 31-10-2018 IPR023214 HAD superfamily DFR85_11065 a4461a6b459fa0a81507febfb31b5f57 218 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 188 5.7E-12 T 31-10-2018 DFR85_11065 a4461a6b459fa0a81507febfb31b5f57 218 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 96 183 4.3E-12 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 DFR85_07930 68e937798879e7a81aa477c8d822113f 211 Hamap MF_00512 30S ribosomal protein S6e [rps6e]. 2 211 27.058 T 31-10-2018 IPR020924 Ribosomal protein S6e, archaeal GO:0003735|GO:0005840|GO:0006412 DFR85_07930 68e937798879e7a81aa477c8d822113f 211 Pfam PF01092 Ribosomal protein S6e 113 210 3.6E-22 T 31-10-2018 IPR001377 Ribosomal protein S6e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07930 68e937798879e7a81aa477c8d822113f 211 SMART SM01405 106 210 1.8E-25 T 31-10-2018 IPR001377 Ribosomal protein S6e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_11725 9096031503faa755fd87f0987b12b23e 361 Gene3D G3DSA:3.40.50.20 6 97 1.0E-23 T 31-10-2018 DFR85_11725 9096031503faa755fd87f0987b12b23e 361 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 8 340 33.448 T 31-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 DFR85_11725 9096031503faa755fd87f0987b12b23e 361 SUPERFAMILY SSF56059 99 289 3.89E-45 T 31-10-2018 DFR85_11725 9096031503faa755fd87f0987b12b23e 361 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 8 344 1.4E-111 T 31-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 DFR85_11725 9096031503faa755fd87f0987b12b23e 361 Gene3D G3DSA:3.30.470.20 177 359 2.4E-52 T 31-10-2018 DFR85_11725 9096031503faa755fd87f0987b12b23e 361 SUPERFAMILY SSF52440 7 94 7.34E-17 T 31-10-2018 IPR016185 Pre-ATP-grasp domain superfamily DFR85_11725 9096031503faa755fd87f0987b12b23e 361 Pfam PF02222 ATP-grasp domain 107 268 1.4E-42 T 31-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type DFR85_11725 9096031503faa755fd87f0987b12b23e 361 Gene3D G3DSA:3.30.1490.20 98 176 8.5E-19 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 DFR85_11725 9096031503faa755fd87f0987b12b23e 361 SUPERFAMILY SSF51246 294 357 2.59E-12 T 31-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 DFR85_04390 0fd3bfa984d3c86d45d7e94d5e15a851 307 Pfam PF00535 Glycosyl transferase family 2 6 125 4.8E-24 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 DFR85_04390 0fd3bfa984d3c86d45d7e94d5e15a851 307 SUPERFAMILY SSF53448 4 232 2.56E-53 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_04390 0fd3bfa984d3c86d45d7e94d5e15a851 307 Gene3D G3DSA:3.90.550.10 1 190 9.3E-51 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_06280 2d9e1f79a3238f9200f29327705a8c02 316 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 11 294 1.0E-95 T 31-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 DFR85_06280 2d9e1f79a3238f9200f29327705a8c02 316 Gene3D G3DSA:3.40.50.300 1 240 1.3E-63 T 31-10-2018 DFR85_06280 2d9e1f79a3238f9200f29327705a8c02 316 Pfam PF13732 Domain of unknown function (DUF4162) 215 292 1.1E-6 T 31-10-2018 IPR025302 Domain of unknown function DUF4162 DFR85_06280 2d9e1f79a3238f9200f29327705a8c02 316 Pfam PF00005 ABC transporter 20 160 2.4E-29 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR85_06280 2d9e1f79a3238f9200f29327705a8c02 316 SUPERFAMILY SSF52540 6 225 6.48E-60 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_06280 2d9e1f79a3238f9200f29327705a8c02 316 SMART SM00382 28 209 3.5E-10 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_08570 5b6295b88fe6a573627a5985f36c0a43 267 Pfam PF01497 Periplasmic binding protein 22 224 4.1E-17 T 31-10-2018 IPR002491 ABC transporter periplasmic binding domain DFR85_08570 5b6295b88fe6a573627a5985f36c0a43 267 Gene3D G3DSA:3.40.50.1980 139 265 1.2E-14 T 31-10-2018 DFR85_08570 5b6295b88fe6a573627a5985f36c0a43 267 SUPERFAMILY SSF53807 14 265 7.85E-41 T 31-10-2018 DFR85_08570 5b6295b88fe6a573627a5985f36c0a43 267 Gene3D G3DSA:3.40.50.1980 19 137 2.1E-22 T 31-10-2018 DFR85_02180 d371391a717863b740e5d4ad7647c85b 630 SUPERFAMILY SSF52922 507 624 7.2E-20 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 DFR85_02180 d371391a717863b740e5d4ad7647c85b 630 Gene3D G3DSA:3.40.50.920 503 619 4.9E-28 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 DFR85_02180 d371391a717863b740e5d4ad7647c85b 630 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 3 612 4.2E-175 T 31-10-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 DFR85_02180 d371391a717863b740e5d4ad7647c85b 630 Gene3D G3DSA:3.40.50.970 221 428 5.5E-67 T 31-10-2018 DFR85_02180 d371391a717863b740e5d4ad7647c85b 630 SUPERFAMILY SSF52518 228 496 3.26E-57 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR85_02180 d371391a717863b740e5d4ad7647c85b 630 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 12 211 2.4E-32 T 31-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 DFR85_02180 d371391a717863b740e5d4ad7647c85b 630 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 517 604 1.8E-10 T 31-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II DFR85_02180 d371391a717863b740e5d4ad7647c85b 630 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 241 488 9.6E-58 T 31-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 DFR85_02180 d371391a717863b740e5d4ad7647c85b 630 SUPERFAMILY SSF53323 2 247 3.4E-14 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 DFR85_14905 bc8c68193b234e3ba06ff04d4228f173 469 TIGRFAM TIGR02734 crtI_fam: phytoene desaturase 3 464 3.5E-91 T 31-10-2018 IPR014105 Carotenoid/retinoid oxidoreductase GO:0016117|GO:0055114 DFR85_14905 bc8c68193b234e3ba06ff04d4228f173 469 SUPERFAMILY SSF51905 1 466 7.2E-54 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_14905 bc8c68193b234e3ba06ff04d4228f173 469 Pfam PF01593 Flavin containing amine oxidoreductase 10 457 2.7E-26 T 31-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 DFR85_14905 bc8c68193b234e3ba06ff04d4228f173 469 PRINTS PR00419 Adrenodoxin reductase family signature 2 24 1.7E-5 T 31-10-2018 DFR85_14905 bc8c68193b234e3ba06ff04d4228f173 469 PRINTS PR00419 Adrenodoxin reductase family signature 25 38 1.7E-5 T 31-10-2018 DFR85_14905 bc8c68193b234e3ba06ff04d4228f173 469 Gene3D G3DSA:3.50.50.60 1 96 5.7E-22 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_14905 bc8c68193b234e3ba06ff04d4228f173 469 Gene3D G3DSA:3.50.50.60 186 309 1.4E-9 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_02120 f8bf59f4945b6be4bf5600bbc0673c4f 451 Gene3D G3DSA:3.50.50.60 139 263 5.8E-89 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_02120 f8bf59f4945b6be4bf5600bbc0673c4f 451 SUPERFAMILY SSF55424 336 449 2.75E-27 T 31-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 DFR85_02120 f8bf59f4945b6be4bf5600bbc0673c4f 451 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 338 445 1.6E-20 T 31-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 DFR85_02120 f8bf59f4945b6be4bf5600bbc0673c4f 451 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 315 9.3E-52 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR85_02120 f8bf59f4945b6be4bf5600bbc0673c4f 451 SUPERFAMILY SSF51905 1 310 6.99E-46 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_02120 f8bf59f4945b6be4bf5600bbc0673c4f 451 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 38 48 - T 31-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 DFR85_02120 f8bf59f4945b6be4bf5600bbc0673c4f 451 Gene3D G3DSA:3.50.50.60 4 314 5.8E-89 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_02120 f8bf59f4945b6be4bf5600bbc0673c4f 451 Gene3D G3DSA:3.30.390.30 336 451 8.0E-30 T 31-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 DFR85_02120 f8bf59f4945b6be4bf5600bbc0673c4f 451 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 421 441 3.3E-49 T 31-10-2018 DFR85_02120 f8bf59f4945b6be4bf5600bbc0673c4f 451 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 3.3E-49 T 31-10-2018 DFR85_02120 f8bf59f4945b6be4bf5600bbc0673c4f 451 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 255 269 3.3E-49 T 31-10-2018 DFR85_02120 f8bf59f4945b6be4bf5600bbc0673c4f 451 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 296 303 3.3E-49 T 31-10-2018 DFR85_02120 f8bf59f4945b6be4bf5600bbc0673c4f 451 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 334 355 3.3E-49 T 31-10-2018 DFR85_02120 f8bf59f4945b6be4bf5600bbc0673c4f 451 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 130 139 3.3E-49 T 31-10-2018 DFR85_02120 f8bf59f4945b6be4bf5600bbc0673c4f 451 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 168 193 3.3E-49 T 31-10-2018 DFR85_02120 f8bf59f4945b6be4bf5600bbc0673c4f 451 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 399 414 3.3E-49 T 31-10-2018 DFR85_02120 f8bf59f4945b6be4bf5600bbc0673c4f 451 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 37 52 3.3E-49 T 31-10-2018 DFR85_02120 f8bf59f4945b6be4bf5600bbc0673c4f 451 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 168 186 7.6E-26 T 31-10-2018 DFR85_02120 f8bf59f4945b6be4bf5600bbc0673c4f 451 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 254 270 7.6E-26 T 31-10-2018 DFR85_02120 f8bf59f4945b6be4bf5600bbc0673c4f 451 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 127 145 7.6E-26 T 31-10-2018 DFR85_02120 f8bf59f4945b6be4bf5600bbc0673c4f 451 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 281 303 7.6E-26 T 31-10-2018 DFR85_02120 f8bf59f4945b6be4bf5600bbc0673c4f 451 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 7.6E-26 T 31-10-2018 DFR85_02120 f8bf59f4945b6be4bf5600bbc0673c4f 451 PIRSF PIRSF000350 1 450 3.2E-62 T 31-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 DFR85_02640 158a7e8c921a34f00e1928a9c371e5b3 344 Gene3D G3DSA:1.10.3720.10 97 337 1.1E-10 T 31-10-2018 IPR035906 MetI-like superfamily DFR85_02640 158a7e8c921a34f00e1928a9c371e5b3 344 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 122 342 2.0E-38 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 DFR85_02640 158a7e8c921a34f00e1928a9c371e5b3 344 SUPERFAMILY SSF161098 101 330 4.41E-10 T 31-10-2018 IPR035906 MetI-like superfamily DFR85_00460 d2d4e31a8f388da4d123a631c65137a8 225 Gene3D G3DSA:3.90.850.10 3 222 1.2E-24 T 31-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 DFR85_00460 d2d4e31a8f388da4d123a631c65137a8 225 SUPERFAMILY SSF56529 4 216 9.77E-24 T 31-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 DFR85_06285 4f6b13b15afd9ca6d7fe6edf0284ea38 255 Pfam PF01061 ABC-2 type transporter 5 220 9.9E-27 T 31-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 DFR85_06285 4f6b13b15afd9ca6d7fe6edf0284ea38 255 PIRSF PIRSF006648 1 253 4.1E-56 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 DFR85_06550 a561f4a917812f5bb114946e904deed9 343 Gene3D G3DSA:3.30.70.360 158 258 4.7E-61 T 31-10-2018 DFR85_06550 a561f4a917812f5bb114946e904deed9 343 Hamap MF_01120 [LysW]-lysine/[LysW]-ornithine hydrolase [lysK]. 10 343 30.008 T 31-10-2018 IPR010175 [LysW]-lysine/[LysW]-ornithine hydrolase GO:0005737|GO:0008270|GO:0009085|GO:0016811|GO:0050897 DFR85_06550 a561f4a917812f5bb114946e904deed9 343 SUPERFAMILY SSF53187 3 343 5.39E-38 T 31-10-2018 DFR85_06550 a561f4a917812f5bb114946e904deed9 343 TIGRFAM TIGR01902 dapE-lys-deAc: N-acetyl-ornithine/N-acetyl-lysine deacetylase 14 342 7.4E-101 T 31-10-2018 IPR010175 [LysW]-lysine/[LysW]-ornithine hydrolase GO:0005737|GO:0008270|GO:0009085|GO:0016811|GO:0050897 DFR85_06550 a561f4a917812f5bb114946e904deed9 343 SUPERFAMILY SSF55031 158 250 3.29E-9 T 31-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain DFR85_06550 a561f4a917812f5bb114946e904deed9 343 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 90 124 - T 31-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 DFR85_06550 a561f4a917812f5bb114946e904deed9 343 Pfam PF07687 Peptidase dimerisation domain 157 243 7.8E-7 T 31-10-2018 IPR011650 Peptidase M20, dimerisation domain DFR85_06550 a561f4a917812f5bb114946e904deed9 343 Pfam PF01546 Peptidase family M20/M25/M40 65 340 5.4E-27 T 31-10-2018 IPR002933 Peptidase M20 GO:0016787 DFR85_06550 a561f4a917812f5bb114946e904deed9 343 Gene3D G3DSA:3.40.630.10 19 329 4.7E-61 T 31-10-2018 DFR85_09370 a23415ad7ab96ae199bbd0a5a4292980 385 SUPERFAMILY SSF51338 313 374 1.73E-5 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR85_09370 a23415ad7ab96ae199bbd0a5a4292980 385 Pfam PF01979 Amidohydrolase family 247 363 1.5E-7 T 31-10-2018 IPR006680 Amidohydrolase-related GO:0016787 DFR85_09370 a23415ad7ab96ae199bbd0a5a4292980 385 Gene3D G3DSA:3.20.20.140 37 382 3.3E-66 T 31-10-2018 DFR85_09370 a23415ad7ab96ae199bbd0a5a4292980 385 SUPERFAMILY SSF51556 46 311 8.23E-55 T 31-10-2018 IPR032466 Metal-dependent hydrolase DFR85_09370 a23415ad7ab96ae199bbd0a5a4292980 385 ProSitePatterns PS00483 Dihydroorotase signature 2. 250 261 - T 31-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 DFR85_08745 1b720aad319e00253a70b2cd998e6560 226 TIGRFAM TIGR01482 SPP-subfamily: sucrose-phosphate phosphatase subfamily 5 220 1.7E-35 T 31-10-2018 DFR85_08745 1b720aad319e00253a70b2cd998e6560 226 Gene3D G3DSA:3.40.50.1000 5 205 7.0E-63 T 31-10-2018 IPR023214 HAD superfamily DFR85_08745 1b720aad319e00253a70b2cd998e6560 226 SUPERFAMILY SSF56784 2 219 5.01E-44 T 31-10-2018 IPR036412 HAD-like superfamily DFR85_08745 1b720aad319e00253a70b2cd998e6560 226 TIGRFAM TIGR01487 Pglycolate_arch: phosphoglycolate phosphatase, TA0175-type 2 215 5.4E-71 T 31-10-2018 DFR85_08745 1b720aad319e00253a70b2cd998e6560 226 Gene3D G3DSA:3.90.1070.10 81 142 7.0E-63 T 31-10-2018 DFR85_08745 1b720aad319e00253a70b2cd998e6560 226 Hamap MF_01419 Phosphoglycolate phosphatase. 2 221 28.083 T 31-10-2018 IPR006382 Phosphoglycolate phosphatase GO:0000287|GO:0008967|GO:0016311 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 DFR85_08745 1b720aad319e00253a70b2cd998e6560 226 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 98 2.5E-12 T 31-10-2018 DFR85_08745 1b720aad319e00253a70b2cd998e6560 226 Pfam PF08282 haloacid dehalogenase-like hydrolase 119 216 1.3E-17 T 31-10-2018 DFR85_00890 91974b2eff0dddd84ff2d133a82e0008 377 SUPERFAMILY SSF51338 2 360 2.75E-6 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR85_00890 91974b2eff0dddd84ff2d133a82e0008 377 Gene3D G3DSA:3.20.20.140 58 190 4.1E-9 T 31-10-2018 DFR85_00890 91974b2eff0dddd84ff2d133a82e0008 377 Gene3D G3DSA:2.30.40.10 265 376 5.8E-7 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR85_00890 91974b2eff0dddd84ff2d133a82e0008 377 SUPERFAMILY SSF51556 68 292 8.04E-11 T 31-10-2018 IPR032466 Metal-dependent hydrolase DFR85_00890 91974b2eff0dddd84ff2d133a82e0008 377 Gene3D G3DSA:2.30.40.10 16 57 4.1E-9 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR85_09555 c2d04770cd86cdfe9c6622b7a24a2a6d 200 ProSitePatterns PS01236 PdxT/SNO family family signature. 46 56 - T 31-10-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 DFR85_09555 c2d04770cd86cdfe9c6622b7a24a2a6d 200 Gene3D G3DSA:3.40.50.880 1 200 5.7E-62 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like DFR85_09555 c2d04770cd86cdfe9c6622b7a24a2a6d 200 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 3 197 32.562 T 31-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 DFR85_09555 c2d04770cd86cdfe9c6622b7a24a2a6d 200 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 2 195 2.4E-55 T 31-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 DFR85_09555 c2d04770cd86cdfe9c6622b7a24a2a6d 200 Pfam PF01174 SNO glutamine amidotransferase family 5 197 1.2E-43 T 31-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 DFR85_09555 c2d04770cd86cdfe9c6622b7a24a2a6d 200 SUPERFAMILY SSF52317 2 198 3.3E-48 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like DFR85_09555 c2d04770cd86cdfe9c6622b7a24a2a6d 200 PIRSF PIRSF005639 1 200 1.0E-65 T 31-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 DFR85_04180 5a66723cc76a87ff562c534074c91492 225 Pfam PF02585 GlcNAc-PI de-N-acetylase 4 129 1.3E-24 T 31-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 DFR85_04180 5a66723cc76a87ff562c534074c91492 225 Gene3D G3DSA:3.40.50.10320 1 222 9.3E-45 T 31-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 DFR85_04180 5a66723cc76a87ff562c534074c91492 225 SUPERFAMILY SSF102588 1 206 3.01E-37 T 31-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 DFR85_01910 83b5bdaaff56c3f20cea57a944dcb871 395 Pfam PF02222 ATP-grasp domain 122 297 5.6E-43 T 31-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type DFR85_01910 83b5bdaaff56c3f20cea57a944dcb871 395 Gene3D G3DSA:3.30.1490.20 124 195 3.3E-27 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 DFR85_01910 83b5bdaaff56c3f20cea57a944dcb871 395 Gene3D G3DSA:3.30.470.20 196 395 1.9E-57 T 31-10-2018 DFR85_01910 83b5bdaaff56c3f20cea57a944dcb871 395 Hamap MF_01643 Formate-dependent phosphoribosylglycinamide formyltransferase [purT]. 7 395 46.522 T 31-10-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 DFR85_01910 83b5bdaaff56c3f20cea57a944dcb871 395 SUPERFAMILY SSF52440 3 111 1.11E-31 T 31-10-2018 IPR016185 Pre-ATP-grasp domain superfamily DFR85_01910 83b5bdaaff56c3f20cea57a944dcb871 395 Gene3D G3DSA:3.40.50.20 1 123 3.3E-47 T 31-10-2018 DFR85_01910 83b5bdaaff56c3f20cea57a944dcb871 395 SUPERFAMILY SSF56059 120 388 1.14E-53 T 31-10-2018 DFR85_15070 71142f04c43d35fde6e34b334de1c5ff 76 SMART SM00966 5 51 2.3E-9 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR85_15070 71142f04c43d35fde6e34b334de1c5ff 76 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 5 46 1.3E-14 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR85_15070 71142f04c43d35fde6e34b334de1c5ff 76 Gene3D G3DSA:2.10.260.10 1 44 4.8E-8 T 31-10-2018 DFR85_15070 71142f04c43d35fde6e34b334de1c5ff 76 SUPERFAMILY SSF89447 3 56 6.28E-12 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily DFR85_15070 71142f04c43d35fde6e34b334de1c5ff 76 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 6 49 6.3E-11 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR85_14475 8857d6f72127a3655c0cd06a1bcbb55b 472 Gene3D G3DSA:1.20.1250.20 250 467 9.6E-20 T 31-10-2018 DFR85_14475 8857d6f72127a3655c0cd06a1bcbb55b 472 Pfam PF07690 Major Facilitator Superfamily 12 401 1.1E-53 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_14475 8857d6f72127a3655c0cd06a1bcbb55b 472 Gene3D G3DSA:1.20.1720.10 7 241 2.5E-44 T 31-10-2018 DFR85_14475 8857d6f72127a3655c0cd06a1bcbb55b 472 SUPERFAMILY SSF103473 4 468 4.58E-67 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_00315 509a30749544899dd515d37bcd933f4c 137 Gene3D G3DSA:1.10.10.10 2 137 4.7E-28 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_00315 509a30749544899dd515d37bcd933f4c 137 SUPERFAMILY SSF46785 9 132 2.37E-26 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_00315 509a30749544899dd515d37bcd933f4c 137 Pfam PF01047 MarR family 33 87 2.4E-10 T 31-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DFR85_00315 509a30749544899dd515d37bcd933f4c 137 SMART SM00347 25 124 1.3E-17 T 31-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DFR85_00315 509a30749544899dd515d37bcd933f4c 137 PRINTS PR00598 Bacterial regulatory protein MarR family signature 48 64 2.3E-7 T 31-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DFR85_00315 509a30749544899dd515d37bcd933f4c 137 PRINTS PR00598 Bacterial regulatory protein MarR family signature 65 80 2.3E-7 T 31-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DFR85_00315 509a30749544899dd515d37bcd933f4c 137 PRINTS PR00598 Bacterial regulatory protein MarR family signature 84 100 2.3E-7 T 31-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DFR85_03065 c61eb5403e8853e25df85c602fd91e22 127 Pfam PF02566 OsmC-like protein 32 124 7.5E-6 T 31-10-2018 IPR003718 OsmC/Ohr family DFR85_03065 c61eb5403e8853e25df85c602fd91e22 127 Gene3D G3DSA:3.30.300.20 10 126 3.9E-7 T 31-10-2018 IPR015946 K homology domain-like, alpha/beta DFR85_03065 c61eb5403e8853e25df85c602fd91e22 127 SUPERFAMILY SSF82784 32 126 1.19E-7 T 31-10-2018 IPR036102 OsmC/Ohr superfamily DFR85_10145 22e93192b23aee788817a08bfa8fcd03 86 SUPERFAMILY SSF160374 2 78 1.44E-20 T 31-10-2018 DFR85_10145 22e93192b23aee788817a08bfa8fcd03 86 Pfam PF01775 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A 21 63 8.9E-12 T 31-10-2018 IPR023573 Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_10145 22e93192b23aee788817a08bfa8fcd03 86 Gene3D G3DSA:3.10.20.10 4 81 3.8E-22 T 31-10-2018 DFR85_10145 22e93192b23aee788817a08bfa8fcd03 86 ProDom PD010302 RIBOSOMAL LX 50S RIBONUCLEOPROTEIN HL32 DIRECT SEQUENCING LXA LSU 7 47 3.0E-11 T 31-10-2018 IPR002768 50S ribosomal protein L18Ae, archaea GO:0003735|GO:0005840|GO:0006412 DFR85_10145 22e93192b23aee788817a08bfa8fcd03 86 Hamap MF_00273 50S ribosomal protein L18Ae [rpl18a]. 4 63 17.853 T 31-10-2018 IPR028877 50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_11760 19e13341bbfbd5830f9505291198618d 220 Gene3D G3DSA:1.10.150.660 17 93 9.6E-63 T 31-10-2018 DFR85_11760 19e13341bbfbd5830f9505291198618d 220 SUPERFAMILY SSF56784 4 211 6.33E-25 T 31-10-2018 IPR036412 HAD-like superfamily DFR85_11760 19e13341bbfbd5830f9505291198618d 220 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 91 185 2.6E-8 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 DFR85_11760 19e13341bbfbd5830f9505291198618d 220 Pfam PF13419 Haloacid dehalogenase-like hydrolase 77 189 2.7E-9 T 31-10-2018 DFR85_11760 19e13341bbfbd5830f9505291198618d 220 Gene3D G3DSA:3.40.50.1000 6 211 9.6E-63 T 31-10-2018 IPR023214 HAD superfamily DFR85_14985 70dfd5c5b77afc9d53e70726e9dc9d32 382 Gene3D G3DSA:3.40.47.10 1 380 5.6E-68 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR85_14985 70dfd5c5b77afc9d53e70726e9dc9d32 382 PIRSF PIRSF000429 6 380 9.2E-14 T 31-10-2018 IPR002155 Thiolase GO:0016747 DFR85_14985 70dfd5c5b77afc9d53e70726e9dc9d32 382 SUPERFAMILY SSF53901 238 377 7.05E-15 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR85_14985 70dfd5c5b77afc9d53e70726e9dc9d32 382 SUPERFAMILY SSF53901 16 207 4.42E-10 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR85_14985 70dfd5c5b77afc9d53e70726e9dc9d32 382 Pfam PF02803 Thiolase, C-terminal domain 263 350 1.2E-5 T 31-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 DFR85_10585 ea5d705a742352bf1c0b858a7f92ffe5 425 SUPERFAMILY SSF53686 26 416 3.93E-102 T 31-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme DFR85_10585 ea5d705a742352bf1c0b858a7f92ffe5 425 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 18 420 40.575 T 31-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 DFR85_10585 ea5d705a742352bf1c0b858a7f92ffe5 425 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 103 117 - T 31-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 DFR85_10585 ea5d705a742352bf1c0b858a7f92ffe5 425 PIRSF PIRSF001413 6 425 3.3E-142 T 31-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 DFR85_10585 ea5d705a742352bf1c0b858a7f92ffe5 425 Gene3D G3DSA:3.40.50.1100 11 235 2.0E-168 T 31-10-2018 DFR85_10585 ea5d705a742352bf1c0b858a7f92ffe5 425 Gene3D G3DSA:3.40.50.1100 10 413 2.0E-168 T 31-10-2018 DFR85_10585 ea5d705a742352bf1c0b858a7f92ffe5 425 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 75 407 6.7E-43 T 31-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme DFR85_10585 ea5d705a742352bf1c0b858a7f92ffe5 425 TIGRFAM TIGR01415 trpB_rel: pyridoxal-phosphate dependent TrpB-like enzyme 10 421 4.1E-188 T 31-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 DFR85_10585 ea5d705a742352bf1c0b858a7f92ffe5 425 PIRSF PIRSF500824 3 425 6.4E-202 T 31-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 DFR85_11485 9a784b543400eeb1d7a93f5c0f6802b9 411 Gene3D G3DSA:1.20.1250.20 9 212 3.9E-15 T 31-10-2018 DFR85_11485 9a784b543400eeb1d7a93f5c0f6802b9 411 Gene3D G3DSA:1.20.1250.20 213 395 1.1E-11 T 31-10-2018 DFR85_11485 9a784b543400eeb1d7a93f5c0f6802b9 411 SUPERFAMILY SSF103473 11 389 2.22E-32 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_11485 9a784b543400eeb1d7a93f5c0f6802b9 411 Pfam PF07690 Major Facilitator Superfamily 216 391 2.2E-11 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_02580 aabc6e3256fa4b77501b14fe5c9093e0 236 Gene3D G3DSA:3.40.50.300 1 233 1.3E-57 T 31-10-2018 DFR85_02580 aabc6e3256fa4b77501b14fe5c9093e0 236 SUPERFAMILY SSF52540 4 215 2.66E-56 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_02580 aabc6e3256fa4b77501b14fe5c9093e0 236 SMART SM00382 28 204 2.3E-12 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_02580 aabc6e3256fa4b77501b14fe5c9093e0 236 Pfam PF00005 ABC transporter 19 159 8.2E-30 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR85_07165 8a1ad4a7de16d8ae7c5b48d8931c02cf 72 Gene3D G3DSA:2.20.25.30 9 72 1.8E-23 T 31-10-2018 IPR011331 Ribosomal protein L37ae/L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_07165 8a1ad4a7de16d8ae7c5b48d8931c02cf 72 Hamap MF_00327 50S ribosomal protein L37Ae [rpl37ae]. 3 72 22.21 T 31-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_07165 8a1ad4a7de16d8ae7c5b48d8931c02cf 72 Pfam PF01780 Ribosomal L37ae protein family 4 71 1.7E-24 T 31-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_07165 8a1ad4a7de16d8ae7c5b48d8931c02cf 72 SUPERFAMILY SSF57829 9 71 2.08E-20 T 31-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 DFR85_05880 69a8aa7c096a15c3e8b4238138ee2254 524 Pfam PF01039 Carboxyl transferase domain 36 522 3.6E-182 T 31-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 DFR85_05880 69a8aa7c096a15c3e8b4238138ee2254 524 SUPERFAMILY SSF52096 251 524 1.66E-90 T 31-10-2018 IPR029045 ClpP/crotonase-like domain superfamily DFR85_05880 69a8aa7c096a15c3e8b4238138ee2254 524 SUPERFAMILY SSF52096 9 264 1.57E-73 T 31-10-2018 IPR029045 ClpP/crotonase-like domain superfamily DFR85_05880 69a8aa7c096a15c3e8b4238138ee2254 524 Gene3D G3DSA:3.90.226.10 4 267 3.0E-92 T 31-10-2018 DFR85_05880 69a8aa7c096a15c3e8b4238138ee2254 524 Gene3D G3DSA:3.90.226.10 268 524 1.8E-92 T 31-10-2018 DFR85_01345 4af6fcdef3e4adfca54e1e2a879ee556 386 Gene3D G3DSA:3.50.50.60 109 252 8.1E-57 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_01345 4af6fcdef3e4adfca54e1e2a879ee556 386 SUPERFAMILY SSF51905 1 318 1.05E-15 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_01345 4af6fcdef3e4adfca54e1e2a879ee556 386 Gene3D G3DSA:3.50.50.60 3 306 8.1E-57 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_01345 4af6fcdef3e4adfca54e1e2a879ee556 386 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 292 2.6E-15 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR85_03100 a792a254ef1e0537db227285e0b1af60 80 ProDom PD188822 UPF0330 AF1997 ST1125.1 AF1689 AF1478 C1_0043 PYRAB04040 PF1222 MM2475 MA1514 3 75 5.0E-15 T 31-10-2018 IPR003847 Putative antitoxin DFR85_03100 a792a254ef1e0537db227285e0b1af60 80 Hamap MF_00794 Putative antitoxin . 2 76 15.8 T 31-10-2018 IPR003847 Putative antitoxin DFR85_03100 a792a254ef1e0537db227285e0b1af60 80 Pfam PF02697 Putative antitoxin 3 73 1.7E-22 T 31-10-2018 IPR003847 Putative antitoxin DFR85_14575 6b6fb36fe37d8c92f3f17540f3937348 156 Pfam PF05942 Archaeal PaREP1/PaREP8 family 35 146 6.0E-38 T 31-10-2018 IPR010268 Archaeal PaREP1 DFR85_14575 6b6fb36fe37d8c92f3f17540f3937348 156 Gene3D G3DSA:1.20.120.330 35 155 4.6E-39 T 31-10-2018 DFR85_03910 9e5e191b14c3d75ea731acc4b2e677c0 215 Pfam PF00127 Copper binding proteins, plastocyanin/azurin family 113 214 6.4E-9 T 31-10-2018 IPR000923 Blue (type 1) copper domain GO:0005507|GO:0009055 DFR85_03910 9e5e191b14c3d75ea731acc4b2e677c0 215 SUPERFAMILY SSF49503 104 214 3.93E-18 T 31-10-2018 IPR008972 Cupredoxin DFR85_03910 9e5e191b14c3d75ea731acc4b2e677c0 215 ProSitePatterns PS00196 Type-1 copper (blue) proteins signature. 191 207 - T 31-10-2018 IPR028871 Blue (type 1) copper protein, binding site DFR85_03910 9e5e191b14c3d75ea731acc4b2e677c0 215 Gene3D G3DSA:2.60.40.420 37 213 1.0E-45 T 31-10-2018 IPR008972 Cupredoxin DFR85_03910 9e5e191b14c3d75ea731acc4b2e677c0 215 ProSitePatterns PS00079 Multicopper oxidases signature 1. 191 211 - T 31-10-2018 IPR033138 Multicopper oxidases, conserved site DFR85_13190 30600275d22091c7741796e57348a943 380 Gene3D G3DSA:1.20.1250.20 6 192 7.7E-8 T 31-10-2018 DFR85_13190 30600275d22091c7741796e57348a943 380 Gene3D G3DSA:1.20.1250.20 200 380 4.0E-7 T 31-10-2018 DFR85_13190 30600275d22091c7741796e57348a943 380 SUPERFAMILY SSF103473 16 378 2.49E-21 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_09140 e0a45f62bd8639949293a783819d63c8 445 Pfam PF01523 Putative modulator of DNA gyrase 15 300 5.9E-37 T 31-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 DFR85_09140 e0a45f62bd8639949293a783819d63c8 445 SUPERFAMILY SSF111283 2 438 1.23E-81 T 31-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 DFR85_09140 e0a45f62bd8639949293a783819d63c8 445 PIRSF PIRSF004919 1 445 2.6E-128 T 31-10-2018 IPR025502 TldD DFR85_07575 550a729e8d2a9b372cab7d29d7f09c72 396 SMART SM01074 302 383 7.6E-32 T 31-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 DFR85_07575 550a729e8d2a9b372cab7d29d7f09c72 396 SUPERFAMILY SSF52540 17 279 3.44E-50 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_07575 550a729e8d2a9b372cab7d29d7f09c72 396 Pfam PF09079 CDC6, C terminal winged helix domain 310 380 8.5E-21 T 31-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 DFR85_07575 550a729e8d2a9b372cab7d29d7f09c72 396 Hamap MF_01407 ORC1-type DNA replication protein. 10 383 32.311 T 31-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea DFR85_07575 550a729e8d2a9b372cab7d29d7f09c72 396 SUPERFAMILY SSF46785 286 385 1.5E-25 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_07575 550a729e8d2a9b372cab7d29d7f09c72 396 Gene3D G3DSA:3.40.50.300 33 206 6.6E-104 T 31-10-2018 DFR85_07575 550a729e8d2a9b372cab7d29d7f09c72 396 Gene3D G3DSA:1.10.8.60 21 286 6.6E-104 T 31-10-2018 DFR85_07575 550a729e8d2a9b372cab7d29d7f09c72 396 SMART SM00382 55 208 4.0E-8 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_07575 550a729e8d2a9b372cab7d29d7f09c72 396 Pfam PF13401 AAA domain 57 178 9.6E-12 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_07575 550a729e8d2a9b372cab7d29d7f09c72 396 Gene3D G3DSA:1.10.10.10 294 395 1.5E-30 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_07575 550a729e8d2a9b372cab7d29d7f09c72 396 TIGRFAM TIGR02928 TIGR02928: orc1/cdc6 family replication initiation protein 17 372 1.3E-135 T 31-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea DFR85_06815 cf10b0a6b6ed052ec96985bce0413c06 87 SUPERFAMILY SSF50182 8 82 7.55E-21 T 31-10-2018 IPR010920 LSM domain superfamily DFR85_06815 cf10b0a6b6ed052ec96985bce0413c06 87 Gene3D G3DSA:2.30.30.100 1 87 2.4E-26 T 31-10-2018 DFR85_06815 cf10b0a6b6ed052ec96985bce0413c06 87 Pfam PF01423 LSM domain 11 76 9.9E-20 T 31-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type DFR85_06815 cf10b0a6b6ed052ec96985bce0413c06 87 SMART SM00651 10 77 8.4E-21 T 31-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type DFR85_15495 52b5c01b3433060341386586d6f41398 558 Gene3D G3DSA:3.30.300.30 440 557 7.2E-29 T 31-10-2018 DFR85_15495 52b5c01b3433060341386586d6f41398 558 Pfam PF13193 AMP-binding enzyme C-terminal domain 453 531 1.6E-23 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain DFR85_15495 52b5c01b3433060341386586d6f41398 558 Gene3D G3DSA:3.40.50.12780 15 438 6.6E-103 T 31-10-2018 DFR85_15495 52b5c01b3433060341386586d6f41398 558 Pfam PF00501 AMP-binding enzyme 48 444 3.7E-69 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 DFR85_15495 52b5c01b3433060341386586d6f41398 558 SUPERFAMILY SSF56801 37 544 7.46E-128 T 31-10-2018 DFR85_15480 fd97a6b143e5267e28f75225a9c83854 259 SUPERFAMILY SSF52540 2 194 1.04E-35 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_15480 fd97a6b143e5267e28f75225a9c83854 259 Pfam PF00005 ABC transporter 17 139 1.2E-19 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR85_15480 fd97a6b143e5267e28f75225a9c83854 259 Gene3D G3DSA:3.40.50.300 2 208 1.5E-37 T 31-10-2018 DFR85_15480 fd97a6b143e5267e28f75225a9c83854 259 ProSitePatterns PS00211 ABC transporters family signature. 112 126 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DFR85_11710 2c9444d87543cd4f8dc338f6688e1f2b 228 Pfam PF00121 Triosephosphate isomerase 5 122 3.3E-14 T 31-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR85_11710 2c9444d87543cd4f8dc338f6688e1f2b 228 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 207 2.4E-45 T 31-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR85_11710 2c9444d87543cd4f8dc338f6688e1f2b 228 Hamap MF_00147_A Triosephosphate isomerase [tpiA]. 3 221 38.213 T 31-10-2018 IPR022891 Triosephosphate isomerase, archaeal GO:0004807|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003 DFR85_11710 2c9444d87543cd4f8dc338f6688e1f2b 228 Gene3D G3DSA:3.20.20.70 1 224 2.9E-77 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_11710 2c9444d87543cd4f8dc338f6688e1f2b 228 SUPERFAMILY SSF51351 1 219 5.63E-43 T 31-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 DFR85_05145 f0589d7dff82d6700446e3c06fa296fd 346 SUPERFAMILY SSF53756 10 345 5.1E-69 T 31-10-2018 DFR85_05145 f0589d7dff82d6700446e3c06fa296fd 346 Gene3D G3DSA:3.40.50.2000 6 176 1.8E-24 T 31-10-2018 DFR85_05145 f0589d7dff82d6700446e3c06fa296fd 346 Pfam PF00534 Glycosyl transferases group 1 168 314 1.0E-30 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 DFR85_05145 f0589d7dff82d6700446e3c06fa296fd 346 Gene3D G3DSA:3.40.50.2000 177 329 2.9E-33 T 31-10-2018 DFR85_07965 acdc499ed4f52ef5e7593e6add2c17bf 771 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 214 343 1.4E-47 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 DFR85_07965 acdc499ed4f52ef5e7593e6add2c17bf 771 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 491 621 6.2E-48 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 DFR85_07965 acdc499ed4f52ef5e7593e6add2c17bf 771 SMART SM01073 6 89 2.5E-27 T 31-10-2018 IPR003338 CDC48, N-terminal subdomain DFR85_07965 acdc499ed4f52ef5e7593e6add2c17bf 771 ProSitePatterns PS00674 AAA-protein family signature. 314 332 - T 31-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 DFR85_07965 acdc499ed4f52ef5e7593e6add2c17bf 771 ProSitePatterns PS00674 AAA-protein family signature. 592 610 - T 31-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 DFR85_07965 acdc499ed4f52ef5e7593e6add2c17bf 771 Gene3D G3DSA:3.10.330.10 90 177 3.7E-5 T 31-10-2018 DFR85_07965 acdc499ed4f52ef5e7593e6add2c17bf 771 SMART SM00382 487 624 2.5E-24 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_07965 acdc499ed4f52ef5e7593e6add2c17bf 771 SMART SM00382 210 346 2.8E-25 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_07965 acdc499ed4f52ef5e7593e6add2c17bf 771 SUPERFAMILY SSF50692 2 87 2.44E-20 T 31-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily DFR85_07965 acdc499ed4f52ef5e7593e6add2c17bf 771 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 6 88 2.2E-23 T 31-10-2018 IPR003338 CDC48, N-terminal subdomain DFR85_07965 acdc499ed4f52ef5e7593e6add2c17bf 771 Gene3D G3DSA:2.40.40.20 1 89 8.3E-22 T 31-10-2018 DFR85_07965 acdc499ed4f52ef5e7593e6add2c17bf 771 Gene3D G3DSA:1.10.8.60 623 746 6.9E-98 T 31-10-2018 DFR85_07965 acdc499ed4f52ef5e7593e6add2c17bf 771 TIGRFAM TIGR01243 CDC48: AAA family ATPase, CDC48 subfamily 5 767 0.0 T 31-10-2018 IPR005938 AAA ATPase, CDC48 family GO:0016787 Reactome: R-HSA-110320|Reactome: R-HSA-3371511|Reactome: R-HSA-382556|Reactome: R-HSA-532668|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5678895|Reactome: R-HSA-5689877|Reactome: R-HSA-5689896|Reactome: R-HSA-6798695|Reactome: R-HSA-8866654|Reactome: R-HSA-8876725 DFR85_07965 acdc499ed4f52ef5e7593e6add2c17bf 771 SUPERFAMILY SSF54585 90 179 8.17E-22 T 31-10-2018 IPR029067 CDC48 domain 2-like superfamily DFR85_07965 acdc499ed4f52ef5e7593e6add2c17bf 771 Pfam PF09336 Vps4 C terminal oligomerisation domain 731 760 3.2E-5 T 31-10-2018 IPR015415 Vps4 oligomerisation, C-terminal DFR85_07965 acdc499ed4f52ef5e7593e6add2c17bf 771 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 104 166 8.0E-16 T 31-10-2018 IPR004201 CDC48, domain 2 DFR85_07965 acdc499ed4f52ef5e7593e6add2c17bf 771 SMART SM01072 104 167 1.8E-17 T 31-10-2018 IPR004201 CDC48, domain 2 DFR85_07965 acdc499ed4f52ef5e7593e6add2c17bf 771 SUPERFAMILY SSF52540 449 764 8.27E-71 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_07965 acdc499ed4f52ef5e7593e6add2c17bf 771 Gene3D G3DSA:3.40.50.300 178 343 9.8E-69 T 31-10-2018 DFR85_07965 acdc499ed4f52ef5e7593e6add2c17bf 771 SUPERFAMILY SSF52540 171 441 4.22E-74 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_07965 acdc499ed4f52ef5e7593e6add2c17bf 771 Gene3D G3DSA:3.40.50.300 449 759 6.9E-98 T 31-10-2018 DFR85_07965 acdc499ed4f52ef5e7593e6add2c17bf 771 Gene3D G3DSA:1.10.8.60 345 443 3.6E-30 T 31-10-2018 DFR85_15720 3ae322c1a593c357693e17cf01dbcf48 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 1.2E-20 T 31-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 DFR85_15720 3ae322c1a593c357693e17cf01dbcf48 386 Gene3D G3DSA:1.20.140.10 236 385 1.6E-33 T 31-10-2018 DFR85_15720 3ae322c1a593c357693e17cf01dbcf48 386 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 219 3.5E-19 T 31-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 DFR85_15720 3ae322c1a593c357693e17cf01dbcf48 386 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 384 2.9E-37 T 31-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 DFR85_15720 3ae322c1a593c357693e17cf01dbcf48 386 Gene3D G3DSA:1.10.540.10 1 119 1.3E-24 T 31-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 DFR85_15720 3ae322c1a593c357693e17cf01dbcf48 386 SUPERFAMILY SSF47203 229 385 4.67E-38 T 31-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 DFR85_15720 3ae322c1a593c357693e17cf01dbcf48 386 Gene3D G3DSA:2.40.110.10 122 235 2.4E-30 T 31-10-2018 DFR85_15720 3ae322c1a593c357693e17cf01dbcf48 386 SUPERFAMILY SSF56645 1 243 3.66E-57 T 31-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 DFR85_04200 5bfb810e1b5707f0cd4519b2d91b0b06 368 Pfam PF01979 Amidohydrolase family 43 365 6.3E-21 T 31-10-2018 IPR006680 Amidohydrolase-related GO:0016787 DFR85_04200 5bfb810e1b5707f0cd4519b2d91b0b06 368 Gene3D G3DSA:2.30.40.10 17 365 4.8E-115 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR85_04200 5bfb810e1b5707f0cd4519b2d91b0b06 368 Gene3D G3DSA:3.20.20.140 47 338 4.8E-115 T 31-10-2018 DFR85_04200 5bfb810e1b5707f0cd4519b2d91b0b06 368 PIRSF PIRSF038994 1 368 3.7E-109 T 31-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 DFR85_04200 5bfb810e1b5707f0cd4519b2d91b0b06 368 SUPERFAMILY SSF51338 3 367 5.4E-12 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR85_04200 5bfb810e1b5707f0cd4519b2d91b0b06 368 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 21 364 1.3E-81 T 31-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 DFR85_04200 5bfb810e1b5707f0cd4519b2d91b0b06 368 SUPERFAMILY SSF51556 47 337 2.14E-84 T 31-10-2018 IPR032466 Metal-dependent hydrolase DFR85_02130 cc937cf290debc3a2f644f462b9b86ba 163 Pfam PF13240 zinc-ribbon domain 140 162 2.5E-7 T 31-10-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 DFR85_14600 3a47d982fa0262c86ea28f1b25a25581 163 Hamap MF_00796 Nucleoside-triphosphatase . 1 162 28.545 T 31-10-2018 IPR004948 Nucleoside-triphosphatase, THEP1 type GO:0098519 KEGG: 00230+3.6.1.15|KEGG: 00730+3.6.1.15|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210 DFR85_14600 3a47d982fa0262c86ea28f1b25a25581 163 Pfam PF03266 NTPase 2 155 2.9E-49 T 31-10-2018 IPR004948 Nucleoside-triphosphatase, THEP1 type GO:0098519 KEGG: 00230+3.6.1.15|KEGG: 00730+3.6.1.15|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210 DFR85_14600 3a47d982fa0262c86ea28f1b25a25581 163 Gene3D G3DSA:3.40.50.300 1 161 1.3E-38 T 31-10-2018 DFR85_14600 3a47d982fa0262c86ea28f1b25a25581 163 SUPERFAMILY SSF52540 3 152 1.13E-18 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_00125 211ceb1cfe8d058155eb7e4980819e95 130 Gene3D G3DSA:3.40.50.300 3 128 9.0E-22 T 31-10-2018 DFR85_00125 211ceb1cfe8d058155eb7e4980819e95 130 SUPERFAMILY SSF52540 6 124 7.79E-17 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_08425 dbb547205db8dccabbe6191f856f35bb 491 Pfam PF00571 CBS domain 380 425 2.0E-7 T 31-10-2018 IPR000644 CBS domain DFR85_08425 dbb547205db8dccabbe6191f856f35bb 491 Pfam PF00999 Sodium/hydrogen exchanger family 3 351 4.5E-30 T 31-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 DFR85_08425 dbb547205db8dccabbe6191f856f35bb 491 SUPERFAMILY SSF54631 368 490 4.93E-13 T 31-10-2018 DFR85_08425 dbb547205db8dccabbe6191f856f35bb 491 Gene3D G3DSA:3.10.580.10 367 490 1.1E-11 T 31-10-2018 DFR85_08425 dbb547205db8dccabbe6191f856f35bb 491 Gene3D G3DSA:1.20.1530.20 1 364 1.6E-44 T 31-10-2018 IPR038770 Sodium/solute symporter superfamily DFR85_11030 be5b2d68e49886afe2fa7055ddfec369 106 Gene3D G3DSA:1.10.10.10 5 106 1.8E-26 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_11030 be5b2d68e49886afe2fa7055ddfec369 106 Pfam PF01638 HxlR-like helix-turn-helix 20 105 3.5E-20 T 31-10-2018 IPR002577 Helix-turn-helix, HxlR type DFR85_11030 be5b2d68e49886afe2fa7055ddfec369 106 SUPERFAMILY SSF46785 7 105 3.33E-26 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_14785 19a0c51261a4a896857be1f16ddcc769 110 Gene3D G3DSA:3.40.1260.10 1 110 1.7E-14 T 31-10-2018 IPR027396 DsrEFH-like DFR85_01065 023a19d3adf2a2a571cd5199290fb55a 286 Pfam PF00902 Sec-independent protein translocase protein (TatC) 18 238 2.6E-46 T 31-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 DFR85_01065 023a19d3adf2a2a571cd5199290fb55a 286 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 14 41 2.9E-37 T 31-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 DFR85_01065 023a19d3adf2a2a571cd5199290fb55a 286 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 181 209 2.9E-37 T 31-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 DFR85_01065 023a19d3adf2a2a571cd5199290fb55a 286 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 129 155 2.9E-37 T 31-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 DFR85_01065 023a19d3adf2a2a571cd5199290fb55a 286 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 111 129 2.9E-37 T 31-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 DFR85_01065 023a19d3adf2a2a571cd5199290fb55a 286 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 11 267 13.48 T 31-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 DFR85_01065 023a19d3adf2a2a571cd5199290fb55a 286 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 15 238 9.9E-40 T 31-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 DFR85_13870 aea11a011d4fdaba4a43ce0619db7c0e 187 SUPERFAMILY SSF53323 5 183 1.57E-47 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 DFR85_13870 aea11a011d4fdaba4a43ce0619db7c0e 187 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 5 180 4.3E-64 T 31-10-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 DFR85_13870 aea11a011d4fdaba4a43ce0619db7c0e 187 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 13 176 3.3E-37 T 31-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 DFR85_13870 aea11a011d4fdaba4a43ce0619db7c0e 187 Gene3D G3DSA:3.40.920.10 4 182 7.8E-56 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 DFR85_09805 dee6218dcfb74bfcc46a1154a2c53eb6 261 Gene3D G3DSA:3.40.50.10860 12 245 6.7E-60 T 31-10-2018 DFR85_09805 dee6218dcfb74bfcc46a1154a2c53eb6 261 SUPERFAMILY SSF53223 3 99 1.32E-26 T 31-10-2018 DFR85_09805 dee6218dcfb74bfcc46a1154a2c53eb6 261 Gene3D G3DSA:3.40.50.720 102 224 6.7E-60 T 31-10-2018 DFR85_09805 dee6218dcfb74bfcc46a1154a2c53eb6 261 SUPERFAMILY SSF51735 120 254 2.85E-26 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_09805 dee6218dcfb74bfcc46a1154a2c53eb6 261 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 8 257 27.626 T 31-10-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 DFR85_09805 dee6218dcfb74bfcc46a1154a2c53eb6 261 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 13 94 6.4E-27 T 31-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 DFR85_02335 40c89de887e34cad0caf705ae0198eb9 300 TIGRFAM TIGR01230 agmatinase: agmatinase 30 291 4.1E-70 T 31-10-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 DFR85_02335 40c89de887e34cad0caf705ae0198eb9 300 Gene3D G3DSA:3.40.800.10 1 299 9.3E-97 T 31-10-2018 DFR85_02335 40c89de887e34cad0caf705ae0198eb9 300 SUPERFAMILY SSF52768 4 296 1.15E-86 T 31-10-2018 IPR023696 Ureohydrolase domain superfamily DFR85_02335 40c89de887e34cad0caf705ae0198eb9 300 ProSitePatterns PS01053 Arginase family signature. 223 244 - T 31-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 DFR85_02335 40c89de887e34cad0caf705ae0198eb9 300 PIRSF PIRSF036979 11 298 7.6E-100 T 31-10-2018 IPR006035 Ureohydrolase GO:0046872 DFR85_02335 40c89de887e34cad0caf705ae0198eb9 300 Pfam PF00491 Arginase family 32 289 2.0E-76 T 31-10-2018 IPR006035 Ureohydrolase GO:0046872 DFR85_12975 446a07e55382cd0b2f1f1794e498a354 109 Gene3D G3DSA:3.30.460.10 16 108 6.4E-17 T 31-10-2018 DFR85_12975 446a07e55382cd0b2f1f1794e498a354 109 SUPERFAMILY SSF81301 20 104 1.69E-14 T 31-10-2018 DFR85_12975 446a07e55382cd0b2f1f1794e498a354 109 Pfam PF01909 Nucleotidyltransferase domain 22 91 4.3E-8 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 DFR85_09780 3dda45dbdc05e91e2aad500d0921cfb7 100 Pfam PF00355 Rieske [2Fe-2S] domain 12 87 4.2E-12 T 31-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 DFR85_09780 3dda45dbdc05e91e2aad500d0921cfb7 100 SUPERFAMILY SSF50022 7 98 2.1E-22 T 31-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 DFR85_09780 3dda45dbdc05e91e2aad500d0921cfb7 100 Gene3D G3DSA:2.102.10.10 3 100 1.2E-19 T 31-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 DFR85_10965 2da9d49c26024feed8a54a6125510db0 459 SUPERFAMILY SSF54909 383 458 2.68E-14 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel DFR85_10965 2da9d49c26024feed8a54a6125510db0 459 Gene3D G3DSA:3.20.20.70 2 270 3.4E-84 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_10965 2da9d49c26024feed8a54a6125510db0 459 SUPERFAMILY SSF51569 4 281 2.38E-77 T 31-10-2018 DFR85_10965 2da9d49c26024feed8a54a6125510db0 459 Pfam PF00682 HMGL-like 4 264 7.1E-70 T 31-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 DFR85_10965 2da9d49c26024feed8a54a6125510db0 459 Pfam PF01037 Lrp/AsnC ligand binding domain 387 457 9.4E-14 T 31-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DFR85_10965 2da9d49c26024feed8a54a6125510db0 459 Gene3D G3DSA:3.30.70.920 380 459 1.7E-16 T 31-10-2018 DFR85_10965 2da9d49c26024feed8a54a6125510db0 459 TIGRFAM TIGR02146 LysS_fung_arch: homocitrate synthase 5 351 6.9E-164 T 31-10-2018 IPR011872 Homocitrate synthase, fungi/archaea GO:0004410|GO:0019752|GO:0019878|GO:0046912 KEGG: 00300+2.3.3.14|KEGG: 00620+2.3.3.14|MetaCyc: PWY-3081|MetaCyc: PWY-7710 DFR85_10965 2da9d49c26024feed8a54a6125510db0 459 Gene3D G3DSA:1.10.238.260 271 376 7.2E-28 T 31-10-2018 DFR85_11410 3765977b4975808d9eba148aa4f89ea8 133 SUPERFAMILY SSF75169 15 133 1.6E-22 T 31-10-2018 IPR027396 DsrEFH-like DFR85_11410 3765977b4975808d9eba148aa4f89ea8 133 Gene3D G3DSA:3.40.1260.10 1 133 3.5E-43 T 31-10-2018 IPR027396 DsrEFH-like DFR85_11410 3765977b4975808d9eba148aa4f89ea8 133 Pfam PF02635 DsrE/DsrF-like family 15 133 3.6E-22 T 31-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein DFR85_09560 aac0ec7831c82c9d1d1abf0e81060d5a 338 Gene3D G3DSA:3.20.20.70 41 334 3.9E-127 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_09560 aac0ec7831c82c9d1d1abf0e81060d5a 338 ProSitePatterns PS01235 PdxS/SNZ family signature. 247 265 - T 31-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 DFR85_09560 aac0ec7831c82c9d1d1abf0e81060d5a 338 SUPERFAMILY SSF51366 60 306 5.18E-62 T 31-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 DFR85_09560 aac0ec7831c82c9d1d1abf0e81060d5a 338 Pfam PF01680 SOR/SNZ family 49 254 5.5E-101 T 31-10-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 DFR85_09560 aac0ec7831c82c9d1d1abf0e81060d5a 338 PIRSF PIRSF029271 38 338 1.3E-147 T 31-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 DFR85_09560 aac0ec7831c82c9d1d1abf0e81060d5a 338 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 46 338 50.574 T 31-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 DFR85_09120 7683250f52761367bed67603557e3d3e 226 Pfam PF03099 Biotin/lipoate A/B protein ligase family 7 124 2.8E-13 T 31-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 DFR85_09120 7683250f52761367bed67603557e3d3e 226 Gene3D G3DSA:3.30.930.10 2 180 7.1E-43 T 31-10-2018 DFR85_09120 7683250f52761367bed67603557e3d3e 226 SUPERFAMILY SSF55681 3 171 1.62E-41 T 31-10-2018 DFR85_09120 7683250f52761367bed67603557e3d3e 226 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 5 178 3.8E-37 T 31-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 DFR85_14415 8cb92508272b6ad742e980007b20dee6 680 SUPERFAMILY SSF54665 3 132 2.22E-26 T 31-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily DFR85_14415 8cb92508272b6ad742e980007b20dee6 680 SMART SM01008 10 115 6.5E-25 T 31-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DFR85_14415 8cb92508272b6ad742e980007b20dee6 680 Gene3D G3DSA:3.30.365.10 2 677 9.4E-140 T 31-10-2018 DFR85_14415 8cb92508272b6ad742e980007b20dee6 680 SUPERFAMILY SSF56003 107 674 1.24E-126 T 31-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 DFR85_14415 8cb92508272b6ad742e980007b20dee6 680 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 10 114 3.4E-15 T 31-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DFR85_14415 8cb92508272b6ad742e980007b20dee6 680 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 131 618 1.4E-106 T 31-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DFR85_14840 5dff0f31960ce6fdbf466f35ec44f0d6 169 Gene3D G3DSA:3.40.50.620 2 169 6.3E-54 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR85_14840 5dff0f31960ce6fdbf466f35ec44f0d6 169 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 2 58 2.6E-17 T 31-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 DFR85_14840 5dff0f31960ce6fdbf466f35ec44f0d6 169 Hamap MF_00243 Nicotinamide-nucleotide adenylyltransferase. 1 169 84.545 T 31-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 DFR85_14840 5dff0f31960ce6fdbf466f35ec44f0d6 169 TIGRFAM TIGR01527 arch_NMN_Atrans: nicotinamide-nucleotide adenylyltransferase 2 168 9.2E-76 T 31-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 DFR85_14840 5dff0f31960ce6fdbf466f35ec44f0d6 169 SUPERFAMILY SSF52374 2 164 8.31E-35 T 31-10-2018 DFR85_14840 5dff0f31960ce6fdbf466f35ec44f0d6 169 Pfam PF01467 Cytidylyltransferase-like 4 134 1.1E-17 T 31-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 DFR85_02450 ed8d40ffae8b60753a6b52c571344c7f 182 Gene3D G3DSA:3.40.920.10 2 181 2.6E-55 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 DFR85_02450 ed8d40ffae8b60753a6b52c571344c7f 182 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 3 180 9.8E-61 T 31-10-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 DFR85_02450 ed8d40ffae8b60753a6b52c571344c7f 182 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 12 175 4.4E-38 T 31-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 DFR85_02450 ed8d40ffae8b60753a6b52c571344c7f 182 SUPERFAMILY SSF53323 3 181 1.12E-47 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 DFR85_09185 43eb1faf95a30070c0ebf67140efd0e4 162 SUPERFAMILY SSF103165 3 161 1.31E-70 T 31-10-2018 IPR036902 Ta1353-like superfamily DFR85_09185 43eb1faf95a30070c0ebf67140efd0e4 162 Pfam PF04008 Adenosine specific kinase 8 161 7.7E-73 T 31-10-2018 IPR007153 Adenosine specific kinase DFR85_09185 43eb1faf95a30070c0ebf67140efd0e4 162 Gene3D G3DSA:3.40.1520.10 1 162 9.8E-77 T 31-10-2018 IPR036902 Ta1353-like superfamily DFR85_04315 667c7623a6fa89eb3eac65c904298880 363 Gene3D G3DSA:3.40.50.2000 180 363 8.7E-42 T 31-10-2018 DFR85_04315 667c7623a6fa89eb3eac65c904298880 363 SUPERFAMILY SSF53756 18 363 4.49E-69 T 31-10-2018 DFR85_04315 667c7623a6fa89eb3eac65c904298880 363 Pfam PF13439 Glycosyltransferase Family 4 20 171 5.9E-15 T 31-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 DFR85_04315 667c7623a6fa89eb3eac65c904298880 363 Gene3D G3DSA:3.40.50.2000 1 179 2.3E-15 T 31-10-2018 DFR85_04315 667c7623a6fa89eb3eac65c904298880 363 Pfam PF00534 Glycosyl transferases group 1 187 337 3.0E-29 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 DFR85_13670 17b6b7663ca68b9296e8aa4828458df4 174 SUPERFAMILY SSF55068 1 165 6.93E-75 T 31-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 DFR85_13670 17b6b7663ca68b9296e8aa4828458df4 174 Pfam PF01625 Peptide methionine sulfoxide reductase 3 153 6.6E-65 T 31-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 DFR85_13670 17b6b7663ca68b9296e8aa4828458df4 174 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 2 148 9.9E-59 T 31-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 DFR85_13670 17b6b7663ca68b9296e8aa4828458df4 174 Gene3D G3DSA:3.30.1060.10 1 162 1.3E-71 T 31-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 DFR85_13670 17b6b7663ca68b9296e8aa4828458df4 174 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 1 158 37.3 T 31-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 DFR85_04385 1e4a93ba9739d52187e23e48e323490d 309 Gene3D G3DSA:3.40.50.150 123 303 4.3E-29 T 31-10-2018 DFR85_04385 1e4a93ba9739d52187e23e48e323490d 309 Pfam PF05050 Methyltransferase FkbM domain 138 290 1.4E-16 T 31-10-2018 IPR006342 Methyltransferase FkbM DFR85_04385 1e4a93ba9739d52187e23e48e323490d 309 SUPERFAMILY SSF53335 78 292 5.02E-37 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR85_04385 1e4a93ba9739d52187e23e48e323490d 309 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 136 258 5.6E-32 T 31-10-2018 IPR006342 Methyltransferase FkbM DFR85_00620 eb6190964624bc985be441e2aafda22e 138 Pfam PF01873 Domain found in IF2B/IF5 22 132 6.3E-34 T 31-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 DFR85_00620 eb6190964624bc985be441e2aafda22e 138 Hamap MF_00232 Translation initiation factor 2 subunit beta [eif2b]. 5 138 29.228 T 31-10-2018 IPR004458 Translation initiation factor 2, beta subunit GO:0003743|GO:0006413 DFR85_00620 eb6190964624bc985be441e2aafda22e 138 SUPERFAMILY SSF100966 5 105 1.7E-24 T 31-10-2018 IPR016189 Translation initiation factor IF2/IF5, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 DFR85_00620 eb6190964624bc985be441e2aafda22e 138 Gene3D G3DSA:3.30.70.3150 33 105 1.2E-28 T 31-10-2018 DFR85_00620 eb6190964624bc985be441e2aafda22e 138 SUPERFAMILY SSF75689 102 137 2.88E-11 T 31-10-2018 IPR016190 Translation initiation factor IF2/IF5, zinc-binding GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 DFR85_00620 eb6190964624bc985be441e2aafda22e 138 SMART SM00653 24 132 2.5E-50 T 31-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 DFR85_11795 9dc25163a5f9edb1037c4ab4b4be6ff5 335 Gene3D G3DSA:1.20.1250.20 3 332 3.3E-10 T 31-10-2018 DFR85_11795 9dc25163a5f9edb1037c4ab4b4be6ff5 335 SUPERFAMILY SSF103473 4 166 3.66E-11 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_11795 9dc25163a5f9edb1037c4ab4b4be6ff5 335 SUPERFAMILY SSF103473 131 332 1.01E-5 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_14260 f6124d3676660e3f75332213464b67e6 303 Gene3D G3DSA:3.90.850.10 87 303 2.1E-83 T 31-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 DFR85_14260 f6124d3676660e3f75332213464b67e6 303 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 92 300 6.3E-68 T 31-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 DFR85_14260 f6124d3676660e3f75332213464b67e6 303 SUPERFAMILY SSF56529 83 301 6.28E-74 T 31-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 DFR85_05925 3f71bed81feaa785edf80ef864d47fde 271 SUPERFAMILY SSF52540 17 194 3.01E-5 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_05925 3f71bed81feaa785edf80ef864d47fde 271 Gene3D G3DSA:3.40.50.300 4 271 3.1E-7 T 31-10-2018 DFR85_01550 b910f2d37b87a6cbfb39dad12fd3e571 109 SUPERFAMILY SSF46785 10 93 4.2E-17 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_01550 b910f2d37b87a6cbfb39dad12fd3e571 109 Gene3D G3DSA:1.10.10.10 4 109 1.4E-21 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_01550 b910f2d37b87a6cbfb39dad12fd3e571 109 Pfam PF03551 Transcriptional regulator PadR-like family 24 85 1.6E-13 T 31-10-2018 IPR005149 Transcription regulator PadR, N-terminal DFR85_14630 dc0059e0815dff9450123ae4c5995ffd 178 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 100 162 4.7E-9 T 31-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal DFR85_14630 dc0059e0815dff9450123ae4c5995ffd 178 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 63 99 4.1E-12 T 31-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal DFR85_14630 dc0059e0815dff9450123ae4c5995ffd 178 Gene3D G3DSA:1.10.12.20 32 103 2.4E-18 T 31-10-2018 DFR85_14630 dc0059e0815dff9450123ae4c5995ffd 178 SUPERFAMILY SSF50249 37 169 3.77E-34 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR85_06665 5401649eb397260b6718243803a575a6 429 TIGRFAM TIGR00458 aspS_nondisc: aspartate--tRNA(Asn) ligase 7 429 4.4E-155 T 31-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 DFR85_06665 5401649eb397260b6718243803a575a6 429 Pfam PF01336 OB-fold nucleic acid binding domain 20 92 5.9E-12 T 31-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 DFR85_06665 5401649eb397260b6718243803a575a6 429 PRINTS PR01042 Aspartyl-tRNA synthetase signature 384 398 7.4E-19 T 31-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR85_06665 5401649eb397260b6718243803a575a6 429 PRINTS PR01042 Aspartyl-tRNA synthetase signature 344 360 7.4E-19 T 31-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR85_06665 5401649eb397260b6718243803a575a6 429 PRINTS PR01042 Aspartyl-tRNA synthetase signature 184 196 7.4E-19 T 31-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR85_06665 5401649eb397260b6718243803a575a6 429 PRINTS PR01042 Aspartyl-tRNA synthetase signature 200 213 7.4E-19 T 31-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR85_06665 5401649eb397260b6718243803a575a6 429 SUPERFAMILY SSF50249 2 102 7.24E-25 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR85_06665 5401649eb397260b6718243803a575a6 429 Pfam PF00152 tRNA synthetases class II (D, K and N) 115 423 9.0E-92 T 31-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 DFR85_06665 5401649eb397260b6718243803a575a6 429 Gene3D G3DSA:3.30.930.10 103 429 9.1E-114 T 31-10-2018 DFR85_06665 5401649eb397260b6718243803a575a6 429 Hamap MF_02075 Aspartate--tRNA(Asp) ligase [aspS]. 2 429 40.086 T 31-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 DFR85_06665 5401649eb397260b6718243803a575a6 429 Gene3D G3DSA:2.40.50.140 1 102 4.3E-25 T 31-10-2018 DFR85_06665 5401649eb397260b6718243803a575a6 429 SUPERFAMILY SSF55681 113 424 9.74E-91 T 31-10-2018 DFR85_06935 cd2b693285dfec826d10e923e7807e86 127 Pfam PF07843 Protein of unknown function (DUF1634) 9 120 5.4E-23 T 31-10-2018 IPR012861 Protein of unknown function DUF1634 DFR85_07645 85c3818e79174fe30dfd1e0b16dc1627 338 Gene3D G3DSA:3.40.440.10 2 334 2.5E-102 T 31-10-2018 DFR85_07645 85c3818e79174fe30dfd1e0b16dc1627 338 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 338 67.345 T 31-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 DFR85_07645 85c3818e79174fe30dfd1e0b16dc1627 338 SUPERFAMILY SSF52540 2 332 3.29E-85 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_07645 85c3818e79174fe30dfd1e0b16dc1627 338 Pfam PF00709 Adenylosuccinate synthetase 142 283 3.8E-36 T 31-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 DFR85_07645 85c3818e79174fe30dfd1e0b16dc1627 338 Pfam PF00709 Adenylosuccinate synthetase 286 328 1.2E-5 T 31-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 DFR85_07645 85c3818e79174fe30dfd1e0b16dc1627 338 Pfam PF00709 Adenylosuccinate synthetase 4 136 1.4E-23 T 31-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 DFR85_07645 85c3818e79174fe30dfd1e0b16dc1627 338 SMART SM00788 2 329 3.7E-119 T 31-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 DFR85_06890 4e951e8c463b7c2798297b001f8578c2 299 PIRSF PIRSF009433 1 299 1.0E-92 T 31-10-2018 IPR009927 Protein of unknown function DUF1464 DFR85_06890 4e951e8c463b7c2798297b001f8578c2 299 Pfam PF07318 Protein of unknown function (DUF1464) 5 286 9.8E-103 T 31-10-2018 IPR009927 Protein of unknown function DUF1464 DFR85_00465 581eb79c40e1d11665659e2f83b916e0 540 SUPERFAMILY SSF53474 301 539 5.98E-57 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold DFR85_00465 581eb79c40e1d11665659e2f83b916e0 540 Gene3D G3DSA:3.40.50.1820 271 540 1.2E-61 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold DFR85_00465 581eb79c40e1d11665659e2f83b916e0 540 SUPERFAMILY SSF82171 50 288 2.09E-14 T 31-10-2018 DFR85_00465 581eb79c40e1d11665659e2f83b916e0 540 Gene3D G3DSA:2.120.10.30 52 202 9.4E-7 T 31-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like DFR85_00465 581eb79c40e1d11665659e2f83b916e0 540 Pfam PF00326 Prolyl oligopeptidase family 342 539 1.9E-45 T 31-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 DFR85_10080 fa3564b8ad42e3a4de7d295420f3e3d4 61 SUPERFAMILY SSF57783 3 42 5.21E-5 T 31-10-2018 DFR85_00205 46230da84fab75022ee5e1533664cfe5 1110 Gene3D G3DSA:2.40.40.20 960 1093 3.4E-36 T 31-10-2018 DFR85_00205 46230da84fab75022ee5e1533664cfe5 1110 Pfam PF01568 Molydopterin dinucleotide binding domain 997 1075 3.9E-14 T 31-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 DFR85_00205 46230da84fab75022ee5e1533664cfe5 1110 Gene3D G3DSA:3.40.228.10 261 519 4.9E-43 T 31-10-2018 DFR85_00205 46230da84fab75022ee5e1533664cfe5 1110 Gene3D G3DSA:3.30.200.50 11 154 1.2E-18 T 31-10-2018 DFR85_00205 46230da84fab75022ee5e1533664cfe5 1110 SUPERFAMILY SSF53706 16 870 4.06E-64 T 31-10-2018 DFR85_00205 46230da84fab75022ee5e1533664cfe5 1110 SUPERFAMILY SSF50692 962 1089 8.14E-26 T 31-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily DFR85_00205 46230da84fab75022ee5e1533664cfe5 1110 Gene3D G3DSA:3.40.50.740 525 812 1.8E-16 T 31-10-2018 DFR85_10100 82a1c3acd8c4c49687642f4c0ac72eee 133 Pfam PF13686 DsrE/DsrF/DrsH-like family 53 129 1.8E-10 T 31-10-2018 IPR032836 DsrE2-like family DFR85_10100 82a1c3acd8c4c49687642f4c0ac72eee 133 Gene3D G3DSA:3.40.1260.10 1 132 2.4E-19 T 31-10-2018 IPR027396 DsrEFH-like DFR85_10100 82a1c3acd8c4c49687642f4c0ac72eee 133 SUPERFAMILY SSF75169 1 131 2.86E-16 T 31-10-2018 IPR027396 DsrEFH-like DFR85_01745 fb401755f00ba29a280239a96338649e 293 Gene3D G3DSA:3.20.20.105 24 215 6.2E-6 T 31-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 DFR85_01745 fb401755f00ba29a280239a96338649e 293 SUPERFAMILY SSF51713 31 239 2.35E-17 T 31-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 DFR85_11190 0837f012b94126a1981177b431ce95b5 290 Hamap MF_00583_A Putative ribose-phosphate pyrophosphokinase [prs]. 2 286 34.945 T 31-10-2018 IPR037514 Ribose-phosphate pyrophosphokinase, archaea GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 DFR85_11190 0837f012b94126a1981177b431ce95b5 290 Pfam PF00156 Phosphoribosyl transferase domain 145 254 4.8E-17 T 31-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 DFR85_11190 0837f012b94126a1981177b431ce95b5 290 Gene3D G3DSA:3.40.50.2020 149 281 1.2E-38 T 31-10-2018 DFR85_11190 0837f012b94126a1981177b431ce95b5 290 Gene3D G3DSA:3.40.50.2020 1 148 7.8E-48 T 31-10-2018 DFR85_11190 0837f012b94126a1981177b431ce95b5 290 SUPERFAMILY SSF53271 84 280 7.8E-33 T 31-10-2018 IPR029057 Phosphoribosyltransferase-like DFR85_11190 0837f012b94126a1981177b431ce95b5 290 SUPERFAMILY SSF53271 1 154 2.04E-35 T 31-10-2018 IPR029057 Phosphoribosyltransferase-like DFR85_11190 0837f012b94126a1981177b431ce95b5 290 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 1 287 1.9E-81 T 31-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 DFR85_11190 0837f012b94126a1981177b431ce95b5 290 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 1 117 2.2E-26 T 31-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 DFR85_11190 0837f012b94126a1981177b431ce95b5 290 SMART SM01400 1 117 2.7E-40 T 31-10-2018 DFR85_13595 66365b9a186d2ca926a3955f50f6d87f 179 Gene3D G3DSA:3.40.50.150 24 179 1.9E-11 T 31-10-2018 DFR85_13595 66365b9a186d2ca926a3955f50f6d87f 179 Pfam PF08241 Methyltransferase domain 47 142 1.2E-4 T 31-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 DFR85_13595 66365b9a186d2ca926a3955f50f6d87f 179 SUPERFAMILY SSF53335 5 163 2.85E-11 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR85_09735 831e4e425e953653c4d0e5d4c02a05ed 211 PIRSF PIRSF000349 1 211 3.9E-72 T 31-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 DFR85_09735 831e4e425e953653c4d0e5d4c02a05ed 211 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 171 178 - T 31-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 DFR85_09735 831e4e425e953653c4d0e5d4c02a05ed 211 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 102 203 5.5E-32 T 31-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 DFR85_09735 831e4e425e953653c4d0e5d4c02a05ed 211 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 9 93 1.7E-28 T 31-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 DFR85_09735 831e4e425e953653c4d0e5d4c02a05ed 211 Gene3D G3DSA:2.40.500.20 94 211 7.5E-44 T 31-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 DFR85_09735 831e4e425e953653c4d0e5d4c02a05ed 211 SUPERFAMILY SSF46609 8 98 3.93E-28 T 31-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 DFR85_09735 831e4e425e953653c4d0e5d4c02a05ed 211 PRINTS PR01703 Manganese superoxide dismutase signature 13 24 7.9E-16 T 31-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 DFR85_09735 831e4e425e953653c4d0e5d4c02a05ed 211 PRINTS PR01703 Manganese superoxide dismutase signature 169 181 7.9E-16 T 31-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 DFR85_09735 831e4e425e953653c4d0e5d4c02a05ed 211 PRINTS PR01703 Manganese superoxide dismutase signature 131 139 7.9E-16 T 31-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 DFR85_09735 831e4e425e953653c4d0e5d4c02a05ed 211 PRINTS PR01703 Manganese superoxide dismutase signature 34 47 7.9E-16 T 31-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 DFR85_09735 831e4e425e953653c4d0e5d4c02a05ed 211 PRINTS PR01703 Manganese superoxide dismutase signature 76 89 7.9E-16 T 31-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 DFR85_09735 831e4e425e953653c4d0e5d4c02a05ed 211 SUPERFAMILY SSF54719 96 209 1.44E-38 T 31-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 DFR85_09735 831e4e425e953653c4d0e5d4c02a05ed 211 Gene3D G3DSA:1.10.287.990 27 93 8.0E-26 T 31-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 DFR85_14550 02fe4b201f1ab1902fc304f369abf434 573 SUPERFAMILY SSF103473 4 198 6.41E-32 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_14550 02fe4b201f1ab1902fc304f369abf434 573 Pfam PF07690 Major Facilitator Superfamily 14 425 2.8E-39 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_14550 02fe4b201f1ab1902fc304f369abf434 573 Gene3D G3DSA:1.20.1250.20 7 230 1.6E-30 T 31-10-2018 DFR85_14550 02fe4b201f1ab1902fc304f369abf434 573 SUPERFAMILY SSF103473 213 549 1.57E-19 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_14550 02fe4b201f1ab1902fc304f369abf434 573 Gene3D G3DSA:1.20.1250.20 283 434 3.2E-15 T 31-10-2018 DFR85_11910 79c46b8e2168b0955ae0ecd8e999fdf5 404 Gene3D G3DSA:2.40.380.10 309 400 4.0E-5 T 31-10-2018 IPR035930 FomD-like superfamily DFR85_11910 79c46b8e2168b0955ae0ecd8e999fdf5 404 SUPERFAMILY SSF159234 291 396 5.36E-17 T 31-10-2018 IPR035930 FomD-like superfamily DFR85_11910 79c46b8e2168b0955ae0ecd8e999fdf5 404 Pfam PF04167 Protein of unknown function (DUF402) 316 379 1.1E-13 T 31-10-2018 IPR007295 Domain of unknown function DUF402 DFR85_15465 4f057f41b494ee42403241b0039e6cad 540 ProSitePatterns PS00455 Putative AMP-binding domain signature. 189 200 - T 31-10-2018 IPR020845 AMP-binding, conserved site DFR85_15465 4f057f41b494ee42403241b0039e6cad 540 Gene3D G3DSA:3.30.300.30 435 539 3.6E-30 T 31-10-2018 DFR85_15465 4f057f41b494ee42403241b0039e6cad 540 SUPERFAMILY SSF56801 19 535 6.8E-131 T 31-10-2018 DFR85_15465 4f057f41b494ee42403241b0039e6cad 540 Gene3D G3DSA:3.40.50.12780 3 433 6.8E-101 T 31-10-2018 DFR85_15465 4f057f41b494ee42403241b0039e6cad 540 Pfam PF13193 AMP-binding enzyme C-terminal domain 448 526 3.2E-23 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain DFR85_15465 4f057f41b494ee42403241b0039e6cad 540 Pfam PF00501 AMP-binding enzyme 38 440 3.0E-78 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 DFR85_11720 a02aa466e000634ccae634960f5d3526 110 SUPERFAMILY SSF46785 1 103 1.27E-13 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_11720 a02aa466e000634ccae634960f5d3526 110 Gene3D G3DSA:1.10.10.10 1 109 3.6E-22 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_11720 a02aa466e000634ccae634960f5d3526 110 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 24 61 5.3E-7 T 31-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 DFR85_00955 e7c6367fd9015ff0d792d1e9774bdc63 215 SUPERFAMILY SSF53850 39 168 1.16E-6 T 31-10-2018 DFR85_00955 e7c6367fd9015ff0d792d1e9774bdc63 215 Gene3D G3DSA:3.40.190.200 2 194 7.6E-48 T 31-10-2018 DFR85_00955 e7c6367fd9015ff0d792d1e9774bdc63 215 Pfam PF12916 Protein of unknown function (DUF3834) 1 195 2.0E-79 T 31-10-2018 IPR024533 Protein of unknown function DUF3834 DFR85_00805 f72e7c349eccd93dddcb9afd89ae19aa 360 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 38 262 6.8E-12 T 31-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 DFR85_00805 f72e7c349eccd93dddcb9afd89ae19aa 360 SUPERFAMILY SSF53649 31 356 1.96E-43 T 31-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 DFR85_01540 05381ee85970816252a12ad123de9e69 82 SUPERFAMILY SSF46785 2 74 3.54E-17 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_01540 05381ee85970816252a12ad123de9e69 82 SMART SM00418 12 79 0.0079 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DFR85_01540 05381ee85970816252a12ad123de9e69 82 Gene3D G3DSA:1.10.10.10 13 77 8.9E-18 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_01540 05381ee85970816252a12ad123de9e69 82 Pfam PF01022 Bacterial regulatory protein, arsR family 15 58 2.5E-11 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DFR85_04535 b8c5fa1eabd00b21a2def46447dc8476 124 Pfam PF05942 Archaeal PaREP1/PaREP8 family 6 115 1.5E-32 T 31-10-2018 IPR010268 Archaeal PaREP1 DFR85_04535 b8c5fa1eabd00b21a2def46447dc8476 124 Gene3D G3DSA:1.20.120.330 1 123 6.5E-50 T 31-10-2018 DFR85_11775 32f0349cd0b160e0afc5bc28ec556c01 441 Pfam PF00206 Lyase 2 315 4.8E-93 T 31-10-2018 IPR022761 Fumarate lyase, N-terminal DFR85_11775 32f0349cd0b160e0afc5bc28ec556c01 441 PRINTS PR00145 Argininosuccinate lyase family signature 147 167 2.7E-7 T 31-10-2018 DFR85_11775 32f0349cd0b160e0afc5bc28ec556c01 441 PRINTS PR00145 Argininosuccinate lyase family signature 105 127 2.7E-7 T 31-10-2018 DFR85_11775 32f0349cd0b160e0afc5bc28ec556c01 441 PRINTS PR00145 Argininosuccinate lyase family signature 290 306 2.7E-7 T 31-10-2018 DFR85_11775 32f0349cd0b160e0afc5bc28ec556c01 441 Gene3D G3DSA:1.10.275.10 2 110 3.4E-33 T 31-10-2018 IPR024083 Fumarase/histidase, N-terminal DFR85_11775 32f0349cd0b160e0afc5bc28ec556c01 441 PRINTS PR00149 Fumarate lyase superfamily signature 106 124 5.8E-24 T 31-10-2018 IPR000362 Fumarate lyase family DFR85_11775 32f0349cd0b160e0afc5bc28ec556c01 441 PRINTS PR00149 Fumarate lyase superfamily signature 242 269 5.8E-24 T 31-10-2018 IPR000362 Fumarate lyase family DFR85_11775 32f0349cd0b160e0afc5bc28ec556c01 441 PRINTS PR00149 Fumarate lyase superfamily signature 152 170 5.8E-24 T 31-10-2018 IPR000362 Fumarate lyase family DFR85_11775 32f0349cd0b160e0afc5bc28ec556c01 441 PRINTS PR00149 Fumarate lyase superfamily signature 290 306 5.8E-24 T 31-10-2018 IPR000362 Fumarate lyase family DFR85_11775 32f0349cd0b160e0afc5bc28ec556c01 441 ProSitePatterns PS00163 Fumarate lyases signature. 290 299 - T 31-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 DFR85_11775 32f0349cd0b160e0afc5bc28ec556c01 441 Pfam PF10415 Fumarase C C-terminus 381 431 2.8E-8 T 31-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 DFR85_11775 32f0349cd0b160e0afc5bc28ec556c01 441 Gene3D G3DSA:1.10.40.30 379 435 2.0E-8 T 31-10-2018 DFR85_11775 32f0349cd0b160e0afc5bc28ec556c01 441 SUPERFAMILY SSF48557 10 416 1.07E-102 T 31-10-2018 IPR008948 L-Aspartase-like GO:0003824 DFR85_11775 32f0349cd0b160e0afc5bc28ec556c01 441 Gene3D G3DSA:1.20.200.10 111 378 8.9E-81 T 31-10-2018 DFR85_06465 9bb3bef3b02dfc463402666a34aecdae 269 Pfam PF01791 DeoC/LacD family aldolase 19 240 2.8E-29 T 31-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 DFR85_06465 9bb3bef3b02dfc463402666a34aecdae 269 PIRSF PIRSF038992 1 269 5.3E-75 T 31-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 DFR85_06465 9bb3bef3b02dfc463402666a34aecdae 269 SMART SM01133 17 241 1.3E-24 T 31-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 DFR85_06465 9bb3bef3b02dfc463402666a34aecdae 269 Gene3D G3DSA:3.20.20.70 1 269 1.6E-69 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_06465 9bb3bef3b02dfc463402666a34aecdae 269 SUPERFAMILY SSF51569 3 257 9.89E-53 T 31-10-2018 DFR85_00135 78f815938676c2a0efffb6d5dc7a68bc 323 Gene3D G3DSA:3.90.550.10 2 219 1.4E-21 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_00135 78f815938676c2a0efffb6d5dc7a68bc 323 SUPERFAMILY SSF53448 19 296 1.23E-30 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_00135 78f815938676c2a0efffb6d5dc7a68bc 323 Pfam PF00535 Glycosyl transferase family 2 19 173 3.6E-17 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 DFR85_14380 bcc379b810bab500c890400d68bb4f28 360 Pfam PF00107 Zinc-binding dehydrogenase 187 318 1.2E-17 T 31-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DFR85_14380 bcc379b810bab500c890400d68bb4f28 360 SUPERFAMILY SSF50129 1 181 1.67E-47 T 31-10-2018 IPR011032 GroES-like superfamily DFR85_14380 bcc379b810bab500c890400d68bb4f28 360 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 67 81 - T 31-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 DFR85_14380 bcc379b810bab500c890400d68bb4f28 360 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 140 3.1E-31 T 31-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DFR85_14380 bcc379b810bab500c890400d68bb4f28 360 Gene3D G3DSA:3.40.50.720 159 305 2.8E-87 T 31-10-2018 DFR85_14380 bcc379b810bab500c890400d68bb4f28 360 SUPERFAMILY SSF51735 150 327 8.57E-33 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_14380 bcc379b810bab500c890400d68bb4f28 360 Gene3D G3DSA:3.90.180.10 12 354 2.8E-87 T 31-10-2018 DFR85_14380 bcc379b810bab500c890400d68bb4f28 360 SMART SM00829 8 357 5.8E-6 T 31-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DFR85_15635 fa97eafda03721f70ffd364e793dcc45 397 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 4.7E-8 T 31-10-2018 DFR85_15635 fa97eafda03721f70ffd364e793dcc45 397 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 283 290 4.7E-8 T 31-10-2018 DFR85_15635 fa97eafda03721f70ffd364e793dcc45 397 Gene3D G3DSA:3.50.50.60 1 390 2.8E-50 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_15635 fa97eafda03721f70ffd364e793dcc45 397 SUPERFAMILY SSF51905 1 320 5.29E-30 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_15635 fa97eafda03721f70ffd364e793dcc45 397 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 154 2.2E-7 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR85_15635 fa97eafda03721f70ffd364e793dcc45 397 SUPERFAMILY SSF54373 173 270 3.61E-7 T 31-10-2018 DFR85_15635 fa97eafda03721f70ffd364e793dcc45 397 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 351 373 1.4E-10 T 31-10-2018 DFR85_15635 fa97eafda03721f70ffd364e793dcc45 397 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.4E-10 T 31-10-2018 DFR85_15635 fa97eafda03721f70ffd364e793dcc45 397 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 141 159 1.4E-10 T 31-10-2018 DFR85_08840 0ed391a473096d7b82019a26974739c2 150 Pfam PF00583 Acetyltransferase (GNAT) family 13 120 9.6E-18 T 31-10-2018 IPR000182 GNAT domain DFR85_08840 0ed391a473096d7b82019a26974739c2 150 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 11 140 1.5E-25 T 31-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 DFR85_08840 0ed391a473096d7b82019a26974739c2 150 Gene3D G3DSA:3.40.630.30 2 148 6.7E-34 T 31-10-2018 DFR85_08840 0ed391a473096d7b82019a26974739c2 150 SUPERFAMILY SSF55729 3 144 2.83E-29 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase DFR85_08635 249dd0d4d942c0056d54b5ddf5164daf 87 Gene3D G3DSA:1.10.10.10 2 79 3.5E-9 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_08635 249dd0d4d942c0056d54b5ddf5164daf 87 Pfam PF14947 Winged helix-turn-helix 7 72 5.4E-6 T 31-10-2018 IPR038723 ArnR1-like, winged helix-turn-helix domain DFR85_08635 249dd0d4d942c0056d54b5ddf5164daf 87 SUPERFAMILY SSF46785 6 72 8.32E-9 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_12995 e9e0d6f44874ed2875553ac4a4e204d4 125 Gene3D G3DSA:2.60.120.10 2 114 8.0E-29 T 31-10-2018 IPR014710 RmlC-like jelly roll fold DFR85_12995 e9e0d6f44874ed2875553ac4a4e204d4 125 ProDom PD080544 SYNTHASE 4.2.1.- LYASE L-ECTOINE DEHYDRATASE N-ACETYLDIAMINOBUTYRATE ECTOINE ENZYME SYNTHASE:ECTOINE ECTC 13 111 0.001 T 31-10-2018 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108 DFR85_12995 e9e0d6f44874ed2875553ac4a4e204d4 125 Pfam PF07883 Cupin domain 43 109 5.4E-19 T 31-10-2018 IPR013096 Cupin 2, conserved barrel DFR85_12995 e9e0d6f44874ed2875553ac4a4e204d4 125 SUPERFAMILY SSF51182 20 119 3.75E-28 T 31-10-2018 IPR011051 RmlC-like cupin domain superfamily DFR85_15820 3f96c73ad3965d5d269e01a6c2b819b5 377 PIRSF PIRSF001369 1 377 1.2E-149 T 31-10-2018 IPR024176 Citrate synthase, bacterial-type DFR85_15820 3f96c73ad3965d5d269e01a6c2b819b5 377 PRINTS PR00143 Citrate synthase signature 172 187 2.0E-45 T 31-10-2018 IPR002020 Citrate synthase GO:0046912 DFR85_15820 3f96c73ad3965d5d269e01a6c2b819b5 377 PRINTS PR00143 Citrate synthase signature 194 222 2.0E-45 T 31-10-2018 IPR002020 Citrate synthase GO:0046912 DFR85_15820 3f96c73ad3965d5d269e01a6c2b819b5 377 PRINTS PR00143 Citrate synthase signature 328 342 2.0E-45 T 31-10-2018 IPR002020 Citrate synthase GO:0046912 DFR85_15820 3f96c73ad3965d5d269e01a6c2b819b5 377 PRINTS PR00143 Citrate synthase signature 248 268 2.0E-45 T 31-10-2018 IPR002020 Citrate synthase GO:0046912 DFR85_15820 3f96c73ad3965d5d269e01a6c2b819b5 377 PRINTS PR00143 Citrate synthase signature 123 136 2.0E-45 T 31-10-2018 IPR002020 Citrate synthase GO:0046912 DFR85_15820 3f96c73ad3965d5d269e01a6c2b819b5 377 PRINTS PR00143 Citrate synthase signature 308 324 2.0E-45 T 31-10-2018 IPR002020 Citrate synthase GO:0046912 DFR85_15820 3f96c73ad3965d5d269e01a6c2b819b5 377 ProSitePatterns PS00480 Citrate synthase signature. 255 267 - T 31-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 DFR85_15820 3f96c73ad3965d5d269e01a6c2b819b5 377 Gene3D G3DSA:1.10.580.10 21 347 3.6E-129 T 31-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 DFR85_15820 3f96c73ad3965d5d269e01a6c2b819b5 377 SUPERFAMILY SSF48256 4 376 1.09E-127 T 31-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 DFR85_15820 3f96c73ad3965d5d269e01a6c2b819b5 377 Pfam PF00285 Citrate synthase, C-terminal domain 7 359 1.1E-121 T 31-10-2018 IPR002020 Citrate synthase GO:0046912 DFR85_15820 3f96c73ad3965d5d269e01a6c2b819b5 377 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 6 376 1.7E-143 T 31-10-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 DFR85_15820 3f96c73ad3965d5d269e01a6c2b819b5 377 Gene3D G3DSA:1.10.230.10 220 322 3.6E-129 T 31-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain DFR85_08930 a5fb325a686d2965542c22f5361401d8 225 SUPERFAMILY SSF53633 10 222 1.44E-23 T 31-10-2018 IPR036393 Acetylglutamate kinase-like superfamily DFR85_08930 a5fb325a686d2965542c22f5361401d8 225 Gene3D G3DSA:3.40.1160.10 9 224 1.0E-39 T 31-10-2018 IPR036393 Acetylglutamate kinase-like superfamily DFR85_08930 a5fb325a686d2965542c22f5361401d8 225 Pfam PF00696 Amino acid kinase family 10 194 1.6E-20 T 31-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 DFR85_04345 91ea2c6acd177e331cbaaefc3240f5ee 369 Gene3D G3DSA:3.40.50.2000 15 362 5.3E-48 T 31-10-2018 DFR85_04345 91ea2c6acd177e331cbaaefc3240f5ee 369 Pfam PF13439 Glycosyltransferase Family 4 14 170 2.8E-8 T 31-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 DFR85_04345 91ea2c6acd177e331cbaaefc3240f5ee 369 SUPERFAMILY SSF53756 13 369 6.73E-52 T 31-10-2018 DFR85_04345 91ea2c6acd177e331cbaaefc3240f5ee 369 Gene3D G3DSA:3.40.50.2000 168 352 5.3E-48 T 31-10-2018 DFR85_04345 91ea2c6acd177e331cbaaefc3240f5ee 369 Pfam PF00534 Glycosyl transferases group 1 179 339 6.9E-25 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 DFR85_05260 e6ae66a0d156898ced8291986067ea3d 401 Pfam PF07282 Putative transposase DNA-binding domain 305 372 1.3E-23 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR85_05260 e6ae66a0d156898ced8291986067ea3d 401 Pfam PF01385 Probable transposase 181 287 9.1E-20 T 31-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 DFR85_05260 e6ae66a0d156898ced8291986067ea3d 401 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 255 330 5.6E-15 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR85_03590 17a882e1cf428d6557b6c8b179ed5e79 626 Pfam PF01496 V-type ATPase 116kDa subunit family 80 326 5.2E-21 T 31-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 DFR85_14935 aee9b9a7445c276c7cbf75f2062addae 270 Pfam PF13520 Amino acid permease 10 261 1.3E-22 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_14935 aee9b9a7445c276c7cbf75f2062addae 270 Gene3D G3DSA:1.20.1740.10 8 268 6.5E-28 T 31-10-2018 DFR85_02035 c6fe884e34907bf1e4185bfe29d6e2fa 469 TIGRFAM TIGR01211 ELP3: radical SAM enzyme/protein acetyltransferase, ELP3 family 3 468 2.0E-203 T 31-10-2018 IPR034687 Elongator complex protein 3-like Reactome: R-HSA-3214847 DFR85_02035 c6fe884e34907bf1e4185bfe29d6e2fa 469 PIRSF PIRSF005669 1 469 3.6E-217 T 31-10-2018 IPR034687 Elongator complex protein 3-like Reactome: R-HSA-3214847 DFR85_02035 c6fe884e34907bf1e4185bfe29d6e2fa 469 Gene3D G3DSA:3.80.30.20 129 285 3.4E-14 T 31-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe DFR85_02035 c6fe884e34907bf1e4185bfe29d6e2fa 469 SUPERFAMILY SSF55729 341 465 3.73E-9 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase DFR85_02035 c6fe884e34907bf1e4185bfe29d6e2fa 469 Pfam PF16199 Radical_SAM C-terminal domain 237 317 4.9E-27 T 31-10-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 DFR85_02035 c6fe884e34907bf1e4185bfe29d6e2fa 469 SMART SM00729 16 276 3.3E-44 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 DFR85_02035 c6fe884e34907bf1e4185bfe29d6e2fa 469 Pfam PF04055 Radical SAM superfamily 21 221 3.4E-21 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR85_02035 c6fe884e34907bf1e4185bfe29d6e2fa 469 Gene3D G3DSA:3.40.630.30 333 469 9.3E-7 T 31-10-2018 DFR85_02035 c6fe884e34907bf1e4185bfe29d6e2fa 469 Pfam PF00583 Acetyltransferase (GNAT) family 357 457 2.5E-6 T 31-10-2018 IPR000182 GNAT domain DFR85_02035 c6fe884e34907bf1e4185bfe29d6e2fa 469 SUPERFAMILY SSF102114 18 283 1.57E-32 T 31-10-2018 DFR85_00665 c67ad038aaaab7862b386fdc35c06e35 178 Pfam PF13023 HD domain 11 146 1.2E-14 T 31-10-2018 IPR006674 HD domain DFR85_00665 c67ad038aaaab7862b386fdc35c06e35 178 Gene3D G3DSA:1.10.3210.10 1 176 2.3E-34 T 31-10-2018 DFR85_00665 c67ad038aaaab7862b386fdc35c06e35 178 SUPERFAMILY SSF109604 11 152 3.87E-25 T 31-10-2018 DFR85_00665 c67ad038aaaab7862b386fdc35c06e35 178 SMART SM00471 27 138 1.6E-9 T 31-10-2018 IPR003607 HD/PDEase domain DFR85_08830 c45e64c2233b59542a2f53778fb2dd01 343 Pfam PF13394 4Fe-4S single cluster domain 30 119 4.0E-7 T 31-10-2018 DFR85_08830 c45e64c2233b59542a2f53778fb2dd01 343 SUPERFAMILY SSF102114 25 206 1.44E-23 T 31-10-2018 DFR85_08830 c45e64c2233b59542a2f53778fb2dd01 343 Gene3D G3DSA:3.20.20.70 25 270 1.0E-12 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_08830 c45e64c2233b59542a2f53778fb2dd01 343 Pfam PF04055 Radical SAM superfamily 33 136 8.8E-9 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR85_06190 5de28b9a485d4d64cf68e7b3768e3e6b 78 SUPERFAMILY SSF64307 2 74 1.96E-8 T 31-10-2018 IPR036868 TusA-like domain superfamily DFR85_06190 5de28b9a485d4d64cf68e7b3768e3e6b 78 Gene3D G3DSA:3.30.110.40 1 76 1.2E-6 T 31-10-2018 IPR036868 TusA-like domain superfamily DFR85_06190 5de28b9a485d4d64cf68e7b3768e3e6b 78 Pfam PF01206 Sulfurtransferase TusA 8 75 3.3E-7 T 31-10-2018 IPR001455 TusA-like domain DFR85_07870 6a9ddc226212ef350c57eee9c3fb2dbe 153 SUPERFAMILY SSF52121 3 141 8.77E-41 T 31-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 DFR85_07870 6a9ddc226212ef350c57eee9c3fb2dbe 153 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 1 141 23.077 T 31-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 DFR85_07870 6a9ddc226212ef350c57eee9c3fb2dbe 153 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 6 138 1.2E-37 T 31-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 DFR85_07870 6a9ddc226212ef350c57eee9c3fb2dbe 153 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 6 141 2.9E-42 T 31-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 DFR85_07870 6a9ddc226212ef350c57eee9c3fb2dbe 153 Gene3D G3DSA:3.40.50.960 1 144 1.4E-35 T 31-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 DFR85_02925 f53d7e2436c9d5d3291eb22eae51184d 192 SUPERFAMILY SSF46955 1 54 4.82E-10 T 31-10-2018 IPR009061 Putative DNA-binding domain superfamily DFR85_02925 f53d7e2436c9d5d3291eb22eae51184d 192 SUPERFAMILY SSF53041 54 186 2.22E-22 T 31-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 DFR85_02925 f53d7e2436c9d5d3291eb22eae51184d 192 Pfam PF00239 Resolvase, N terminal domain 56 185 1.2E-18 T 31-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 DFR85_02925 f53d7e2436c9d5d3291eb22eae51184d 192 SMART SM00857 56 192 1.5E-20 T 31-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 DFR85_02925 f53d7e2436c9d5d3291eb22eae51184d 192 Gene3D G3DSA:1.10.1660.10 1 55 1.3E-9 T 31-10-2018 DFR85_02925 f53d7e2436c9d5d3291eb22eae51184d 192 ProSitePatterns PS00397 Site-specific recombinases active site. 59 67 - T 31-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 DFR85_02925 f53d7e2436c9d5d3291eb22eae51184d 192 Gene3D G3DSA:3.40.50.1390 56 150 1.4E-27 T 31-10-2018 DFR85_02925 f53d7e2436c9d5d3291eb22eae51184d 192 Pfam PF12728 Helix-turn-helix domain 1 47 8.4E-11 T 31-10-2018 DFR85_15585 9ef4459a8a53e91bd960e7470d3eb01d 80 SUPERFAMILY SSF89447 6 51 9.68E-9 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily DFR85_15585 9ef4459a8a53e91bd960e7470d3eb01d 80 Gene3D G3DSA:2.10.260.10 1 47 2.0E-7 T 31-10-2018 DFR85_15585 9ef4459a8a53e91bd960e7470d3eb01d 80 SMART SM00966 7 49 6.0E-6 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR85_15585 9ef4459a8a53e91bd960e7470d3eb01d 80 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 7 44 1.9E-8 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR85_15585 9ef4459a8a53e91bd960e7470d3eb01d 80 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 11 47 1.6E-6 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR85_11630 f191301cc398d184be456677322b7eba 277 Pfam PF00892 EamA-like transporter family 10 130 7.3E-10 T 31-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 DFR85_11630 f191301cc398d184be456677322b7eba 277 Pfam PF00892 EamA-like transporter family 141 266 2.5E-20 T 31-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 DFR85_11630 f191301cc398d184be456677322b7eba 277 SUPERFAMILY SSF103481 61 130 3.14E-6 T 31-10-2018 DFR85_11630 f191301cc398d184be456677322b7eba 277 SUPERFAMILY SSF103481 180 266 8.63E-17 T 31-10-2018 DFR85_10540 cbf2f14c28c6afc47129c4a6280cc914 326 SUPERFAMILY SSF51905 3 257 4.4E-10 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_10540 cbf2f14c28c6afc47129c4a6280cc914 326 Gene3D G3DSA:3.50.50.60 3 101 7.6E-6 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_10540 cbf2f14c28c6afc47129c4a6280cc914 326 Gene3D G3DSA:3.50.50.60 102 324 3.1E-18 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_14315 ab363291bc6f5c6565d97286c18b61fc 144 SMART SM00347 27 126 1.5E-15 T 31-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DFR85_14315 ab363291bc6f5c6565d97286c18b61fc 144 Pfam PF01047 MarR family 44 90 2.4E-10 T 31-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DFR85_14315 ab363291bc6f5c6565d97286c18b61fc 144 Gene3D G3DSA:1.10.10.10 1 143 6.5E-34 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_14315 ab363291bc6f5c6565d97286c18b61fc 144 SUPERFAMILY SSF46785 5 141 3.25E-28 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_14465 4523bac033a0ca4b3a259147650ef681 258 Pfam PF01738 Dienelactone hydrolase family 18 255 2.6E-62 T 31-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 DFR85_14465 4523bac033a0ca4b3a259147650ef681 258 SUPERFAMILY SSF53474 13 257 1.74E-37 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold DFR85_13330 337d7b0d44424debd170edc004f4ab62 358 SUPERFAMILY SSF53335 3 264 3.23E-16 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR85_13330 337d7b0d44424debd170edc004f4ab62 358 Gene3D G3DSA:3.40.50.150 3 91 5.0E-7 T 31-10-2018 DFR85_13330 337d7b0d44424debd170edc004f4ab62 358 Pfam PF02086 D12 class N6 adenine-specific DNA methyltransferase 11 246 6.7E-5 T 31-10-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 DFR85_14370 0bd82f5b9cc209bc2131c30e05963faf 268 Pfam PF02332 Methane/Phenol/Toluene Hydroxylase 25 254 1.7E-66 T 31-10-2018 IPR003430 Methane/phenol/toluene hydroxylase GO:0006725|GO:0055114 DFR85_14370 0bd82f5b9cc209bc2131c30e05963faf 268 SUPERFAMILY SSF47240 10 254 5.77E-61 T 31-10-2018 IPR009078 Ferritin-like superfamily DFR85_14370 0bd82f5b9cc209bc2131c30e05963faf 268 Gene3D G3DSA:1.10.620.20 4 267 1.3E-82 T 31-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 DFR85_01480 6b18dd579d2d42159ccffed4cd7c759b 143 PRINTS PR00332 Histidine triad family signature 91 101 1.4E-8 T 31-10-2018 IPR001310 Histidine triad (HIT) protein DFR85_01480 6b18dd579d2d42159ccffed4cd7c759b 143 PRINTS PR00332 Histidine triad family signature 3 19 1.4E-8 T 31-10-2018 IPR001310 Histidine triad (HIT) protein DFR85_01480 6b18dd579d2d42159ccffed4cd7c759b 143 PRINTS PR00332 Histidine triad family signature 24 42 1.4E-8 T 31-10-2018 IPR001310 Histidine triad (HIT) protein DFR85_01480 6b18dd579d2d42159ccffed4cd7c759b 143 Gene3D G3DSA:3.30.428.10 2 143 4.0E-36 T 31-10-2018 IPR036265 HIT-like superfamily DFR85_01480 6b18dd579d2d42159ccffed4cd7c759b 143 ProSitePatterns PS00892 HIT domain signature. 84 102 - T 31-10-2018 IPR019808 Histidine triad, conserved site DFR85_01480 6b18dd579d2d42159ccffed4cd7c759b 143 Pfam PF01230 HIT domain 13 102 4.3E-21 T 31-10-2018 IPR001310 Histidine triad (HIT) protein DFR85_01480 6b18dd579d2d42159ccffed4cd7c759b 143 SUPERFAMILY SSF54197 2 121 7.11E-35 T 31-10-2018 IPR036265 HIT-like superfamily DFR85_02165 f4d29e603d201c26197081cf78bd6fb2 704 SMART SM00926 1 50 5.0E-5 T 31-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_02165 f4d29e603d201c26197081cf78bd6fb2 704 SUPERFAMILY SSF53706 5 561 1.83E-115 T 31-10-2018 DFR85_02165 f4d29e603d201c26197081cf78bd6fb2 704 Gene3D G3DSA:2.40.40.20 561 704 2.4E-34 T 31-10-2018 DFR85_02165 f4d29e603d201c26197081cf78bd6fb2 704 Pfam PF00384 Molybdopterin oxidoreductase 53 489 5.3E-38 T 31-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_02165 f4d29e603d201c26197081cf78bd6fb2 704 SUPERFAMILY SSF50692 538 701 5.42E-28 T 31-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily DFR85_02165 f4d29e603d201c26197081cf78bd6fb2 704 Pfam PF01568 Molydopterin dinucleotide binding domain 577 692 3.7E-17 T 31-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 DFR85_02165 f4d29e603d201c26197081cf78bd6fb2 704 Gene3D G3DSA:2.20.25.90 3 55 4.0E-9 T 31-10-2018 DFR85_12795 766ed76d6326bb308b907a4d139712be 296 SUPERFAMILY SSF102114 25 238 2.09E-21 T 31-10-2018 DFR85_12795 766ed76d6326bb308b907a4d139712be 296 SMART SM00729 25 226 5.3E-14 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 DFR85_12795 766ed76d6326bb308b907a4d139712be 296 Pfam PF04055 Radical SAM superfamily 30 170 9.4E-12 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR85_12795 766ed76d6326bb308b907a4d139712be 296 Gene3D G3DSA:3.20.20.70 12 251 7.7E-14 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_03140 0c4421c1ccefe7716e1c54c6ef427659 426 SUPERFAMILY SSF53383 5 422 2.27E-87 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase DFR85_03140 0c4421c1ccefe7716e1c54c6ef427659 426 Pfam PF00202 Aminotransferase class-III 33 340 9.3E-62 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 DFR85_03140 0c4421c1ccefe7716e1c54c6ef427659 426 Gene3D G3DSA:3.40.640.10 71 315 9.5E-136 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR85_03140 0c4421c1ccefe7716e1c54c6ef427659 426 Gene3D G3DSA:3.90.1150.10 13 413 9.5E-136 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 DFR85_04275 57754e180f8f5484967697b81bf350cc 545 Gene3D G3DSA:3.40.720.10 259 424 5.0E-31 T 31-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 DFR85_04275 57754e180f8f5484967697b81bf350cc 545 Gene3D G3DSA:3.40.720.10 23 196 8.3E-26 T 31-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 DFR85_04275 57754e180f8f5484967697b81bf350cc 545 SUPERFAMILY SSF53649 136 451 2.46E-7 T 31-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 DFR85_04275 57754e180f8f5484967697b81bf350cc 545 Pfam PF04185 Phosphoesterase family 32 385 4.6E-70 T 31-10-2018 IPR007312 Phosphoesterase GO:0016788 DFR85_13955 872fdfeed18b5a5b7c7b7cabec3ea8de 195 SUPERFAMILY SSF55729 9 162 1.03E-13 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase DFR85_13955 872fdfeed18b5a5b7c7b7cabec3ea8de 195 Gene3D G3DSA:3.40.630.30 5 173 5.2E-16 T 31-10-2018 DFR85_13955 872fdfeed18b5a5b7c7b7cabec3ea8de 195 Pfam PF13302 Acetyltransferase (GNAT) domain 45 148 6.7E-7 T 31-10-2018 IPR000182 GNAT domain DFR85_06005 9e3c68ad15720f1f4a2694601018e64a 206 Gene3D G3DSA:3.40.50.2020 4 184 1.4E-36 T 31-10-2018 DFR85_06005 9e3c68ad15720f1f4a2694601018e64a 206 Pfam PF00156 Phosphoribosyl transferase domain 19 148 1.4E-17 T 31-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 DFR85_06005 9e3c68ad15720f1f4a2694601018e64a 206 SUPERFAMILY SSF53271 9 167 7.47E-36 T 31-10-2018 IPR029057 Phosphoribosyltransferase-like DFR85_04150 3ecb5925c5f510d705b5a30b4e128113 86 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 2 82 4.7E-14 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 DFR85_04150 3ecb5925c5f510d705b5a30b4e128113 86 Gene3D G3DSA:3.40.50.300 1 85 2.0E-6 T 31-10-2018 DFR85_04150 3ecb5925c5f510d705b5a30b4e128113 86 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 2 64 3.1E-14 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 DFR85_10775 829609e20e847f62ec357778cbc8ca7f 123 SUPERFAMILY SSF46785 4 69 8.68E-12 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_10775 829609e20e847f62ec357778cbc8ca7f 123 Gene3D G3DSA:1.10.10.10 6 67 6.0E-7 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_10775 829609e20e847f62ec357778cbc8ca7f 123 Pfam PF04182 B-block binding subunit of TFIIIC 18 64 1.1E-6 T 31-10-2018 IPR007309 B-block binding subunit of TFIIIC Reactome: R-HSA-749476|Reactome: R-HSA-76061|Reactome: R-HSA-76066 DFR85_14095 f29a9198ec01d2cdaa698c967537620b 386 Pfam PF00374 Nickel-dependent hydrogenase 286 364 1.9E-13 T 31-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 DFR85_14095 f29a9198ec01d2cdaa698c967537620b 386 Gene3D G3DSA:1.10.645.10 227 368 6.9E-22 T 31-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_14095 f29a9198ec01d2cdaa698c967537620b 386 SUPERFAMILY SSF56762 8 368 1.7E-45 T 31-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_14095 f29a9198ec01d2cdaa698c967537620b 386 Gene3D G3DSA:1.10.645.10 8 226 9.0E-18 T 31-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_07070 6e9791d393b3c1b1c0304e391a67c6e5 76 TIGRFAM TIGR00012 L29: ribosomal protein uL29 11 66 5.4E-14 T 31-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07070 6e9791d393b3c1b1c0304e391a67c6e5 76 SUPERFAMILY SSF46561 10 69 3.53E-14 T 31-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07070 6e9791d393b3c1b1c0304e391a67c6e5 76 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 5 66 13.119 T 31-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07070 6e9791d393b3c1b1c0304e391a67c6e5 76 Pfam PF00831 Ribosomal L29 protein 11 66 1.6E-14 T 31-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07070 6e9791d393b3c1b1c0304e391a67c6e5 76 Gene3D G3DSA:1.20.58.1890 3 70 1.6E-18 T 31-10-2018 DFR85_06730 b1f950ec907fc64aab83d1261f82958d 218 Gene3D G3DSA:3.40.50.10090 119 217 8.3E-9 T 31-10-2018 DFR85_06730 b1f950ec907fc64aab83d1261f82958d 218 Gene3D G3DSA:3.40.50.10090 1 103 4.5E-13 T 31-10-2018 DFR85_06730 b1f950ec907fc64aab83d1261f82958d 218 Pfam PF02602 Uroporphyrinogen-III synthase HemD 10 192 2.6E-23 T 31-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 DFR85_06730 b1f950ec907fc64aab83d1261f82958d 218 SUPERFAMILY SSF69618 8 214 2.22E-31 T 31-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 DFR85_03200 1dc5679cf4235d7eb21d29791316bc38 383 Pfam PF01548 Transposase 12 154 2.2E-20 T 31-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 DFR85_03200 1dc5679cf4235d7eb21d29791316bc38 383 Pfam PF02371 Transposase IS116/IS110/IS902 family 236 317 3.7E-23 T 31-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 DFR85_03050 ae1640808bc41867572c02f5660a4d96 338 Gene3D G3DSA:1.20.1250.20 1 132 1.3E-16 T 31-10-2018 DFR85_03050 ae1640808bc41867572c02f5660a4d96 338 Pfam PF07690 Major Facilitator Superfamily 1 283 8.4E-13 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_03050 ae1640808bc41867572c02f5660a4d96 338 SUPERFAMILY SSF103473 1 328 9.81E-28 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_03050 ae1640808bc41867572c02f5660a4d96 338 Gene3D G3DSA:1.20.1250.20 133 338 1.2E-10 T 31-10-2018 DFR85_02160 1aab0cb6ef79d703a42abeb7914b71fd 494 SUPERFAMILY SSF53720 3 481 3.01E-157 T 31-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 DFR85_02160 1aab0cb6ef79d703a42abeb7914b71fd 494 Pfam PF00171 Aldehyde dehydrogenase family 13 476 1.8E-162 T 31-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 DFR85_02160 1aab0cb6ef79d703a42abeb7914b71fd 494 Gene3D G3DSA:3.40.309.10 253 446 4.6E-163 T 31-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 DFR85_02160 1aab0cb6ef79d703a42abeb7914b71fd 494 Gene3D G3DSA:3.40.605.10 9 474 4.6E-163 T 31-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 DFR85_02160 1aab0cb6ef79d703a42abeb7914b71fd 494 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 248 255 - T 31-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 DFR85_02160 1aab0cb6ef79d703a42abeb7914b71fd 494 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 276 287 - T 31-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 DFR85_09070 17cf1487c607f7643c30ae4491c9460b 240 Pfam PF08241 Methyltransferase domain 93 181 2.9E-16 T 31-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 DFR85_09070 17cf1487c607f7643c30ae4491c9460b 240 SUPERFAMILY SSF53335 53 229 1.33E-24 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR85_09070 17cf1487c607f7643c30ae4491c9460b 240 Gene3D G3DSA:3.40.50.150 44 228 2.6E-24 T 31-10-2018 DFR85_15075 7cc84382e91ff7314fdb106b2e1b93fa 144 SUPERFAMILY SSF88723 12 130 2.8E-9 T 31-10-2018 IPR029060 PIN-like domain superfamily DFR85_15075 7cc84382e91ff7314fdb106b2e1b93fa 144 Pfam PF01850 PIN domain 12 129 4.9E-9 T 31-10-2018 IPR002716 PIN domain DFR85_15075 7cc84382e91ff7314fdb106b2e1b93fa 144 Gene3D G3DSA:3.40.50.1010 11 142 2.9E-5 T 31-10-2018 DFR85_14180 154d67091087bce317f5e38af361d16c 475 Gene3D G3DSA:1.20.1740.10 7 467 2.1E-30 T 31-10-2018 DFR85_14180 154d67091087bce317f5e38af361d16c 475 PIRSF PIRSF006060 6 474 2.4E-41 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_14180 154d67091087bce317f5e38af361d16c 475 Pfam PF13520 Amino acid permease 19 446 4.2E-16 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_02195 1d0235459aa7264cda5f307a067e8fe5 379 Gene3D G3DSA:1.20.1250.20 4 379 2.1E-47 T 31-10-2018 DFR85_02195 1d0235459aa7264cda5f307a067e8fe5 379 Pfam PF07690 Major Facilitator Superfamily 10 236 9.4E-17 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_02195 1d0235459aa7264cda5f307a067e8fe5 379 SUPERFAMILY SSF103473 4 377 2.88E-47 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_03365 b85d999b4bfc8c5dc2fd2292a26b3cf2 421 Pfam PF01523 Putative modulator of DNA gyrase 19 285 2.0E-25 T 31-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 DFR85_03365 b85d999b4bfc8c5dc2fd2292a26b3cf2 421 SUPERFAMILY SSF111283 4 419 9.02E-54 T 31-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 DFR85_14230 3f345001ab7a3866763d791d3790378f 292 SUPERFAMILY SSF103501 177 291 1.22E-15 T 31-10-2018 IPR036197 NarG-like superfamily DFR85_00755 8060f650378c00e686b4cb20ad3427fe 197 Gene3D G3DSA:3.40.50.10240 29 153 1.1E-5 T 31-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 DFR85_00755 8060f650378c00e686b4cb20ad3427fe 197 SUPERFAMILY SSF63999 32 113 1.15E-11 T 31-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 DFR85_00755 8060f650378c00e686b4cb20ad3427fe 197 Pfam PF01973 Protein of unknown function DUF115 17 156 2.2E-29 T 31-10-2018 IPR002826 6-hydroxymethylpterin diphosphokinase MptE-like DFR85_00755 8060f650378c00e686b4cb20ad3427fe 197 Hamap MF_02131 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase [mptE]. 1 196 28.729 T 31-10-2018 IPR027510 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, MptE GO:0003848|GO:0005524 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 DFR85_15355 618f41bb107f507d7b5335f96a26a649 320 SUPERFAMILY SSF56796 7 317 1.83E-52 T 31-10-2018 DFR85_15355 618f41bb107f507d7b5335f96a26a649 320 Gene3D G3DSA:3.40.50.1970 2 146 6.6E-24 T 31-10-2018 DFR85_15355 618f41bb107f507d7b5335f96a26a649 320 Gene3D G3DSA:1.20.1090.10 150 320 4.7E-28 T 31-10-2018 DFR85_15355 618f41bb107f507d7b5335f96a26a649 320 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 311 2.2E-43 T 31-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 DFR85_14925 422263f99368843813946c3ce9a5b15b 433 Pfam PF07282 Putative transposase DNA-binding domain 315 381 1.9E-23 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR85_14925 422263f99368843813946c3ce9a5b15b 433 Pfam PF01385 Probable transposase 194 299 2.1E-13 T 31-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 DFR85_14925 422263f99368843813946c3ce9a5b15b 433 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 264 342 1.2E-18 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR85_09870 ab03f8afd4d605d1e8347f8b69539564 90 Hamap MF_00261 DNA-directed RNA polymerase subunit L [rpoL]. 1 87 18.463 T 31-10-2018 IPR022905 DNA-directed RNA polymerase subunit L (Rpo11) GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR85_09870 ab03f8afd4d605d1e8347f8b69539564 90 ProSitePatterns PS01154 RNA polymerases L / 13 to 16 Kd subunits signature. 17 48 - T 31-10-2018 IPR008193 DNA-directed RNA polymerase Rpb11, 13-16kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 DFR85_09870 ab03f8afd4d605d1e8347f8b69539564 90 Gene3D G3DSA:3.30.1360.10 1 90 2.8E-25 T 31-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR85_09870 ab03f8afd4d605d1e8347f8b69539564 90 Pfam PF13656 RNA polymerase Rpb3/Rpb11 dimerisation domain 13 84 5.8E-19 T 31-10-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 DFR85_09870 ab03f8afd4d605d1e8347f8b69539564 90 SUPERFAMILY SSF55257 2 86 2.75E-21 T 31-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 DFR85_07345 1f97a89da73415d21a2ee69cfb350b13 149 Pfam PF09895 RecB-family nuclease (DUF2122) 38 142 1.7E-33 T 31-10-2018 IPR018665 Protein of unknown function DUF2122, RecB-family nuclease-related DFR85_02520 aa0fc26806e82400765ba4b3848c8bef 160 SUPERFAMILY SSF69737 83 133 1.7E-5 T 31-10-2018 IPR036675 UreE, C-terminal domain superfamily GO:0016151|GO:0019627|GO:0065003 DFR85_02520 aa0fc26806e82400765ba4b3848c8bef 160 Gene3D G3DSA:3.30.70.790 82 157 5.4E-8 T 31-10-2018 IPR036675 UreE, C-terminal domain superfamily GO:0016151|GO:0019627|GO:0065003 DFR85_12800 299a0ab9842388edaeb06ffbae481305 347 SMART SM00729 34 261 7.5E-23 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 DFR85_12800 299a0ab9842388edaeb06ffbae481305 347 SUPERFAMILY SSF102114 33 277 1.27E-32 T 31-10-2018 DFR85_12800 299a0ab9842388edaeb06ffbae481305 347 Pfam PF04055 Radical SAM superfamily 42 218 2.4E-10 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR85_12800 299a0ab9842388edaeb06ffbae481305 347 Gene3D G3DSA:3.20.20.70 29 278 6.3E-22 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_11890 c3a0820ce10c359e2cbe08f25ace7f4d 277 ProSitePatterns PS00125 Serine/threonine specific protein phosphatases signature. 98 103 - T 31-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 DFR85_11890 c3a0820ce10c359e2cbe08f25ace7f4d 277 SMART SM00156 7 276 5.6E-66 T 31-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 DFR85_11890 c3a0820ce10c359e2cbe08f25ace7f4d 277 Pfam PF00149 Calcineurin-like phosphoesterase 38 227 3.3E-25 T 31-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 DFR85_11890 c3a0820ce10c359e2cbe08f25ace7f4d 277 Gene3D G3DSA:3.60.21.10 3 276 1.7E-69 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like DFR85_11890 c3a0820ce10c359e2cbe08f25ace7f4d 277 PRINTS PR00114 Serine/threonine phosphatase family signature 160 187 2.2E-23 T 31-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 DFR85_11890 c3a0820ce10c359e2cbe08f25ace7f4d 277 PRINTS PR00114 Serine/threonine phosphatase family signature 64 91 2.2E-23 T 31-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 DFR85_11890 c3a0820ce10c359e2cbe08f25ace7f4d 277 PRINTS PR00114 Serine/threonine phosphatase family signature 97 121 2.2E-23 T 31-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 DFR85_11890 c3a0820ce10c359e2cbe08f25ace7f4d 277 PRINTS PR00114 Serine/threonine phosphatase family signature 218 238 2.2E-23 T 31-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 DFR85_11890 c3a0820ce10c359e2cbe08f25ace7f4d 277 PRINTS PR00114 Serine/threonine phosphatase family signature 244 260 2.2E-23 T 31-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 DFR85_11890 c3a0820ce10c359e2cbe08f25ace7f4d 277 SUPERFAMILY SSF56300 8 270 6.38E-62 T 31-10-2018 DFR85_03110 febd8d6c1511585a105322c96bf76725 482 Pfam PF13237 4Fe-4S dicluster domain 412 463 3.1E-7 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR85_03110 febd8d6c1511585a105322c96bf76725 482 Gene3D G3DSA:3.30.70.20 397 479 2.5E-8 T 31-10-2018 DFR85_03110 febd8d6c1511585a105322c96bf76725 482 SUPERFAMILY SSF54862 414 472 3.35E-11 T 31-10-2018 DFR85_04840 eb40eb511512ebd1d212f8720efb320c 216 Gene3D G3DSA:3.40.50.300 12 141 1.7E-5 T 31-10-2018 DFR85_04840 eb40eb511512ebd1d212f8720efb320c 216 Pfam PF13175 AAA ATPase domain 26 124 3.3E-11 T 31-10-2018 DFR85_07775 6f5847e7ce51e3b6d71cd13660e67be4 193 PIRSF PIRSF002122 5 193 6.6E-44 T 31-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 DFR85_07775 6f5847e7ce51e3b6d71cd13660e67be4 193 Pfam PF00177 Ribosomal protein S7p/S5e 53 193 1.6E-41 T 31-10-2018 IPR023798 Ribosomal protein S7 domain DFR85_07775 6f5847e7ce51e3b6d71cd13660e67be4 193 ProSitePatterns PS00052 Ribosomal protein S7 signature. 59 85 - T 31-10-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07775 6f5847e7ce51e3b6d71cd13660e67be4 193 Gene3D G3DSA:1.10.455.10 1 193 6.6E-81 T 31-10-2018 IPR036823 Ribosomal protein S7 domain superfamily DFR85_07775 6f5847e7ce51e3b6d71cd13660e67be4 193 Hamap MF_00480_A 30S ribosomal protein S7 [rpsG]. 10 193 39.999 T 31-10-2018 IPR026018 Ribosomal protein S7, archaeal DFR85_07775 6f5847e7ce51e3b6d71cd13660e67be4 193 SUPERFAMILY SSF47973 13 193 6.28E-60 T 31-10-2018 IPR036823 Ribosomal protein S7 domain superfamily DFR85_07775 6f5847e7ce51e3b6d71cd13660e67be4 193 TIGRFAM TIGR01028 uS7_euk_arch: ribosomal protein uS7 9 193 1.7E-79 T 31-10-2018 IPR005716 Ribosomal protein S5/S7, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_10035 7e736ebf77e5f5a9f59824399323d316 285 PIRSF PIRSF004884 1 285 2.0E-80 T 31-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 DFR85_10035 7e736ebf77e5f5a9f59824399323d316 285 TIGRFAM TIGR00144 beta_RFAP_syn: beta-ribofuranosylaminobenzene 5'-phosphate synthase family 45 260 2.7E-57 T 31-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 DFR85_13280 e9ab37350b2ff8e01923d8af47e5e4ab 172 Pfam PF05942 Archaeal PaREP1/PaREP8 family 15 137 1.8E-22 T 31-10-2018 IPR010268 Archaeal PaREP1 DFR85_15165 8c059da9b8e3126d78f1962c1b656024 305 Gene3D G3DSA:3.60.15.10 1 228 1.2E-22 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR85_15165 8c059da9b8e3126d78f1962c1b656024 305 SMART SM00849 23 212 1.3E-8 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR85_15165 8c059da9b8e3126d78f1962c1b656024 305 Pfam PF00753 Metallo-beta-lactamase superfamily 35 212 9.6E-8 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR85_15165 8c059da9b8e3126d78f1962c1b656024 305 SUPERFAMILY SSF56281 9 224 1.49E-20 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR85_03460 5c6af7738e41cc7a2a0d80f53126203f 89 Gene3D G3DSA:1.10.10.1150 3 85 1.8E-12 T 31-10-2018 DFR85_03460 5c6af7738e41cc7a2a0d80f53126203f 89 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 19 84 4.5E-17 T 31-10-2018 IPR008792 Coenzyme PQQ synthesis D DFR85_13150 fb515ed81fd9c2eeaf996dee9241bdfd 232 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 5 46 1.5E-10 T 31-10-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal DFR85_13150 fb515ed81fd9c2eeaf996dee9241bdfd 232 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 5 67 1.1E-6 T 31-10-2018 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 DFR85_08940 05706505fa0886e5f29dc332c1b29868 327 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 207 219 - T 31-10-2018 IPR033749 Polyprenyl synthetase, conserved site DFR85_08940 05706505fa0886e5f29dc332c1b29868 327 SUPERFAMILY SSF48576 2 326 4.89E-92 T 31-10-2018 IPR008949 Isoprenoid synthase domain superfamily DFR85_08940 05706505fa0886e5f29dc332c1b29868 327 Pfam PF00348 Polyprenyl synthetase 28 279 1.3E-73 T 31-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 DFR85_08940 05706505fa0886e5f29dc332c1b29868 327 Gene3D G3DSA:1.10.600.10 1 327 9.3E-102 T 31-10-2018 IPR008949 Isoprenoid synthase domain superfamily DFR85_08940 05706505fa0886e5f29dc332c1b29868 327 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 78 92 - T 31-10-2018 IPR033749 Polyprenyl synthetase, conserved site DFR85_15630 e8c180362b20f7f922f24a8ff71ff5a9 95 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 64 75 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR85_15630 e8c180362b20f7f922f24a8ff71ff5a9 95 PIRSF PIRSF036548 1 95 1.6E-20 T 31-10-2018 IPR012206 Ferredoxin-like, FixX GO:0005506 DFR85_15630 e8c180362b20f7f922f24a8ff71ff5a9 95 SUPERFAMILY SSF54862 22 92 2.2E-19 T 31-10-2018 DFR85_15630 e8c180362b20f7f922f24a8ff71ff5a9 95 Gene3D G3DSA:3.30.70.20 6 89 2.0E-19 T 31-10-2018 DFR85_15630 e8c180362b20f7f922f24a8ff71ff5a9 95 Pfam PF05187 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S 12 89 5.9E-13 T 31-10-2018 DFR85_00445 7b77bd13e0de3b953af2fb0e37ea0879 201 SUPERFAMILY SSF103473 19 160 4.19E-12 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_00445 7b77bd13e0de3b953af2fb0e37ea0879 201 Gene3D G3DSA:1.20.1250.20 8 201 2.3E-8 T 31-10-2018 DFR85_09475 06054823001f16aff1e5b3ed41492975 174 Pfam PF01923 Cobalamin adenosyltransferase 2 156 5.0E-45 T 31-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 DFR85_09475 06054823001f16aff1e5b3ed41492975 174 Gene3D G3DSA:1.20.1200.10 19 174 9.0E-49 T 31-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 DFR85_09475 06054823001f16aff1e5b3ed41492975 174 SUPERFAMILY SSF89028 1 168 1.83E-54 T 31-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 DFR85_09475 06054823001f16aff1e5b3ed41492975 174 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 2 168 9.1E-62 T 31-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 DFR85_09475 06054823001f16aff1e5b3ed41492975 174 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 7 169 2.0E-66 T 31-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 DFR85_11095 0f419b72dbd7c1061062ec7701310611 577 Gene3D G3DSA:1.50.10.10 209 577 9.6E-79 T 31-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 DFR85_11095 0f419b72dbd7c1061062ec7701310611 577 SUPERFAMILY SSF48208 182 576 3.33E-89 T 31-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 DFR85_11095 0f419b72dbd7c1061062ec7701310611 577 Pfam PF00723 Glycosyl hydrolases family 15 212 522 5.1E-45 T 31-10-2018 IPR011613 GH15-like domain Reactome: R-HSA-70221 DFR85_10830 8ebca53c525ba7ca4e3e3537a60cfce1 358 SUPERFAMILY SSF102114 68 280 8.5E-16 T 31-10-2018 DFR85_10830 8ebca53c525ba7ca4e3e3537a60cfce1 358 TIGRFAM TIGR03972 rSAM_TYW1: wyosine biosynthesis protein TYW1 16 316 2.9E-127 T 31-10-2018 IPR023993 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, archaea GO:0008033|GO:0016829|GO:0051539 MetaCyc: PWY-7285|MetaCyc: PWY-7286 DFR85_10830 8ebca53c525ba7ca4e3e3537a60cfce1 358 Gene3D G3DSA:3.20.20.70 11 325 1.1E-112 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_10830 8ebca53c525ba7ca4e3e3537a60cfce1 358 Pfam PF04055 Radical SAM superfamily 66 251 1.2E-20 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR85_10830 8ebca53c525ba7ca4e3e3537a60cfce1 358 Hamap MF_01921 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase [taw1]. 14 317 46.167 T 31-10-2018 IPR023993 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, archaea GO:0008033|GO:0016829|GO:0051539 MetaCyc: PWY-7285|MetaCyc: PWY-7286 DFR85_10830 8ebca53c525ba7ca4e3e3537a60cfce1 358 Pfam PF08608 Wyosine base formation 257 317 5.5E-22 T 31-10-2018 IPR013917 tRNA wybutosine-synthesis MetaCyc: PWY-7285|MetaCyc: PWY-7286 DFR85_02780 35cee735203e96edbd78d5b33a77d578 648 Gene3D G3DSA:3.30.365.10 509 522 2.2E-16 T 31-10-2018 DFR85_02780 35cee735203e96edbd78d5b33a77d578 648 Gene3D G3DSA:3.30.365.10 386 488 2.4E-14 T 31-10-2018 DFR85_02780 35cee735203e96edbd78d5b33a77d578 648 Gene3D G3DSA:3.90.1170.50 4 104 5.5E-9 T 31-10-2018 DFR85_02780 35cee735203e96edbd78d5b33a77d578 648 SUPERFAMILY SSF54665 6 104 1.11E-10 T 31-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily DFR85_02780 35cee735203e96edbd78d5b33a77d578 648 SUPERFAMILY SSF56003 104 635 4.84E-88 T 31-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 DFR85_02780 35cee735203e96edbd78d5b33a77d578 648 Gene3D G3DSA:3.30.365.10 523 644 2.2E-16 T 31-10-2018 DFR85_02780 35cee735203e96edbd78d5b33a77d578 648 Gene3D G3DSA:3.30.365.10 371 385 2.4E-14 T 31-10-2018 DFR85_02780 35cee735203e96edbd78d5b33a77d578 648 Gene3D G3DSA:3.30.365.10 142 233 2.3E-49 T 31-10-2018 DFR85_02780 35cee735203e96edbd78d5b33a77d578 648 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 108 581 3.5E-76 T 31-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DFR85_02780 35cee735203e96edbd78d5b33a77d578 648 Gene3D G3DSA:3.30.365.10 120 344 2.3E-49 T 31-10-2018 DFR85_12090 7e8f98cc11ec250b038ea33d3ded74ce 335 TIGRFAM TIGR03876 cas_csaX: CRISPR type I-A/APERN-associated protein CsaX 31 306 3.7E-94 T 31-10-2018 IPR022297 CRISPR-associated protein, CsaX DFR85_14330 50824137a0b48d273b67938060d9e16f 326 SUPERFAMILY SSF51556 3 326 1.08E-63 T 31-10-2018 IPR032466 Metal-dependent hydrolase DFR85_14330 50824137a0b48d273b67938060d9e16f 326 Gene3D G3DSA:3.20.20.140 2 326 1.5E-71 T 31-10-2018 DFR85_14330 50824137a0b48d273b67938060d9e16f 326 Pfam PF04909 Amidohydrolase 4 325 8.4E-33 T 31-10-2018 IPR006680 Amidohydrolase-related GO:0016787 DFR85_11075 52226a4eae5a255db850899ee6ff1ad8 225 Gene3D G3DSA:3.20.20.140 1 225 4.1E-43 T 31-10-2018 DFR85_11075 52226a4eae5a255db850899ee6ff1ad8 225 PIRSF PIRSF005902 1 225 1.6E-35 T 31-10-2018 IPR001130 TatD family GO:0016788 DFR85_11075 52226a4eae5a255db850899ee6ff1ad8 225 SUPERFAMILY SSF51556 2 225 6.81E-39 T 31-10-2018 IPR032466 Metal-dependent hydrolase DFR85_11075 52226a4eae5a255db850899ee6ff1ad8 225 Pfam PF01026 TatD related DNase 4 224 2.8E-29 T 31-10-2018 IPR001130 TatD family GO:0016788 DFR85_00300 3fe7ee3a75dabc4a170fab9a2372813f 304 SUPERFAMILY SSF52540 2 223 9.92E-53 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_00300 3fe7ee3a75dabc4a170fab9a2372813f 304 SMART SM00382 29 219 1.2E-8 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_00300 3fe7ee3a75dabc4a170fab9a2372813f 304 Pfam PF00005 ABC transporter 21 164 3.0E-27 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR85_00300 3fe7ee3a75dabc4a170fab9a2372813f 304 Gene3D G3DSA:3.40.50.300 2 244 2.2E-58 T 31-10-2018 DFR85_00215 8e2b6d3601b0338b723ad0249afaf067 527 SUPERFAMILY SSF81442 10 479 5.36E-72 T 31-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_00215 8e2b6d3601b0338b723ad0249afaf067 527 PRINTS PR01165 Cytochrome c oxidase subunit I signature 329 347 4.4E-18 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_00215 8e2b6d3601b0338b723ad0249afaf067 527 PRINTS PR01165 Cytochrome c oxidase subunit I signature 411 432 4.4E-18 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_00215 8e2b6d3601b0338b723ad0249afaf067 527 PRINTS PR01165 Cytochrome c oxidase subunit I signature 53 76 4.4E-18 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_00215 8e2b6d3601b0338b723ad0249afaf067 527 PRINTS PR01165 Cytochrome c oxidase subunit I signature 357 376 4.4E-18 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_00215 8e2b6d3601b0338b723ad0249afaf067 527 PRINTS PR01165 Cytochrome c oxidase subunit I signature 268 283 4.4E-18 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_00215 8e2b6d3601b0338b723ad0249afaf067 527 PRINTS PR01165 Cytochrome c oxidase subunit I signature 292 313 4.4E-18 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_00215 8e2b6d3601b0338b723ad0249afaf067 527 PRINTS PR01165 Cytochrome c oxidase subunit I signature 222 243 4.4E-18 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_00215 8e2b6d3601b0338b723ad0249afaf067 527 Gene3D G3DSA:1.20.210.10 10 484 1.1E-68 T 31-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_00215 8e2b6d3601b0338b723ad0249afaf067 527 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 12 452 3.1E-67 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_00215 8e2b6d3601b0338b723ad0249afaf067 527 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 224 278 - T 31-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_03025 8705444fcda4af38712c74a32d7afeab 217 Pfam PF01048 Phosphorylase superfamily 17 197 4.1E-20 T 31-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 DFR85_03025 8705444fcda4af38712c74a32d7afeab 217 SUPERFAMILY SSF53167 8 201 8.64E-37 T 31-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 DFR85_03025 8705444fcda4af38712c74a32d7afeab 217 Gene3D G3DSA:3.40.50.1580 5 215 3.0E-35 T 31-10-2018 DFR85_01470 c6742c23a7c58561924f1272e09f0ef6 275 Pfam PF01261 Xylose isomerase-like TIM barrel 25 223 2.5E-24 T 31-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain DFR85_01470 c6742c23a7c58561924f1272e09f0ef6 275 Gene3D G3DSA:3.20.20.150 8 272 2.1E-35 T 31-10-2018 DFR85_01470 c6742c23a7c58561924f1272e09f0ef6 275 SUPERFAMILY SSF51658 4 269 1.43E-50 T 31-10-2018 IPR036237 Xylose isomerase-like superfamily DFR85_01470 c6742c23a7c58561924f1272e09f0ef6 275 SMART SM00518 8 267 2.3E-62 T 31-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 DFR85_01470 c6742c23a7c58561924f1272e09f0ef6 275 ProSitePatterns PS00729 AP endonucleases family 2 signature 1. 67 75 - T 31-10-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 DFR85_03490 e8689e802a2833c1f4f7a835dcc30cf1 251 Gene3D G3DSA:3.40.50.300 1 250 1.1E-61 T 31-10-2018 DFR85_03490 e8689e802a2833c1f4f7a835dcc30cf1 251 SMART SM00382 28 214 7.1E-14 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_03490 e8689e802a2833c1f4f7a835dcc30cf1 251 Pfam PF00005 ABC transporter 19 165 9.8E-31 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR85_03490 e8689e802a2833c1f4f7a835dcc30cf1 251 SUPERFAMILY SSF52540 4 227 5.32E-59 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_04265 617fafca38beed75666743b42ad59a54 369 Gene3D G3DSA:3.40.50.2000 2 193 4.5E-8 T 31-10-2018 DFR85_04265 617fafca38beed75666743b42ad59a54 369 Pfam PF00534 Glycosyl transferases group 1 200 346 8.6E-25 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 DFR85_04265 617fafca38beed75666743b42ad59a54 369 Gene3D G3DSA:3.40.50.2000 194 353 5.9E-32 T 31-10-2018 DFR85_04265 617fafca38beed75666743b42ad59a54 369 SUPERFAMILY SSF53756 4 365 4.54E-54 T 31-10-2018 DFR85_03560 a76f41002a2aa61fd46d2d0c3cb197d8 107 Gene3D G3DSA:1.20.1300.10 2 107 4.3E-8 T 31-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 DFR85_03560 a76f41002a2aa61fd46d2d0c3cb197d8 107 SUPERFAMILY SSF81343 4 106 7.85E-9 T 31-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 DFR85_01445 365b95c948349cbe21269b09fda09fc9 341 TIGRFAM TIGR00303 TIGR00303: TIGR00303 family protein 10 333 7.7E-107 T 31-10-2018 IPR002805 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative DFR85_01445 365b95c948349cbe21269b09fda09fc9 341 Hamap MF_01086 UPF0284 protein . 1 341 123.847 T 31-10-2018 IPR002805 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative DFR85_01445 365b95c948349cbe21269b09fda09fc9 341 Gene3D G3DSA:3.40.50.10210 11 341 3.8E-113 T 31-10-2018 DFR85_01445 365b95c948349cbe21269b09fda09fc9 341 SUPERFAMILY SSF52733 32 337 1.96E-41 T 31-10-2018 IPR036087 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 DFR85_09585 e280e2f45e81bac9bf7e4b27a621719b 213 Pfam PF01813 ATP synthase subunit D 12 202 2.3E-39 T 31-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 DFR85_09585 e280e2f45e81bac9bf7e4b27a621719b 213 TIGRFAM TIGR00309 V_ATPase_subD: V-type ATPase, D subunit 4 206 8.6E-29 T 31-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 DFR85_09585 e280e2f45e81bac9bf7e4b27a621719b 213 Hamap MF_00271 V-type ATP synthase subunit D [atpD]. 3 208 22.444 T 31-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 DFR85_06325 4ca9c031861124b2440fa121ac7e9e9b 302 Gene3D G3DSA:3.30.420.40 106 273 6.4E-89 T 31-10-2018 DFR85_06325 4ca9c031861124b2440fa121ac7e9e9b 302 SUPERFAMILY SSF53067 1 104 3.24E-15 T 31-10-2018 DFR85_06325 4ca9c031861124b2440fa121ac7e9e9b 302 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 4 285 1.2E-36 T 31-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 DFR85_06325 4ca9c031861124b2440fa121ac7e9e9b 302 SUPERFAMILY SSF53067 107 291 7.24E-44 T 31-10-2018 DFR85_06325 4ca9c031861124b2440fa121ac7e9e9b 302 Gene3D G3DSA:3.30.420.40 3 285 6.4E-89 T 31-10-2018 DFR85_10495 01c99fcc576ab7524713411d2f2db1fb 94 ProSitePatterns PS01111 RNA polymerases K / 14 to 18 Kd subunits signature. 23 37 - T 31-10-2018 IPR020708 DNA-directed RNA polymerase, 14-18kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 DFR85_10495 01c99fcc576ab7524713411d2f2db1fb 94 SMART SM01409 16 73 1.5E-4 T 31-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 DFR85_10495 01c99fcc576ab7524713411d2f2db1fb 94 Gene3D G3DSA:3.90.940.10 3 92 3.4E-28 T 31-10-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 DFR85_10495 01c99fcc576ab7524713411d2f2db1fb 94 Pfam PF01192 RNA polymerase Rpb6 21 73 5.5E-11 T 31-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 DFR85_10495 01c99fcc576ab7524713411d2f2db1fb 94 Hamap MF_00192 DNA-directed RNA polymerase subunit K [rpoK]. 20 79 19.014 T 31-10-2018 IPR006111 Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 DFR85_10495 01c99fcc576ab7524713411d2f2db1fb 94 SUPERFAMILY SSF63562 15 92 2.88E-23 T 31-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 DFR85_10495 01c99fcc576ab7524713411d2f2db1fb 94 PIRSF PIRSF000778 5 93 8.7E-28 T 31-10-2018 IPR006111 Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 DFR85_04725 c9cdad22a66412bb77f66717227785cc 76 Pfam PF07362 Post-segregation antitoxin CcdA 7 48 1.5E-6 T 31-10-2018 IPR009956 Post-segregation antitoxin CcdA DFR85_04705 19b374ff2353368fde61616858eb2b9d 75 Gene3D G3DSA:2.10.260.10 1 41 3.4E-8 T 31-10-2018 DFR85_04705 19b374ff2353368fde61616858eb2b9d 75 SUPERFAMILY SSF89447 2 43 8.89E-8 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily DFR85_04705 19b374ff2353368fde61616858eb2b9d 75 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 1 43 9.4E-15 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR85_04705 19b374ff2353368fde61616858eb2b9d 75 SMART SM00966 2 48 6.6E-7 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR85_15345 c2ebde83d61d4633a2db37ce12316c87 283 Gene3D G3DSA:3.20.20.140 1 281 3.2E-43 T 31-10-2018 DFR85_15345 c2ebde83d61d4633a2db37ce12316c87 283 Pfam PF04909 Amidohydrolase 71 279 7.2E-25 T 31-10-2018 IPR006680 Amidohydrolase-related GO:0016787 DFR85_15345 c2ebde83d61d4633a2db37ce12316c87 283 SUPERFAMILY SSF51556 4 280 3.8E-36 T 31-10-2018 IPR032466 Metal-dependent hydrolase DFR85_05615 ceb4488ba5d3489b1cddd5fb9d603d73 44 Pfam PF12916 Protein of unknown function (DUF3834) 1 27 4.6E-7 T 31-10-2018 IPR024533 Protein of unknown function DUF3834 DFR85_11460 d8919bc1a51d72c3f734cf697362db1c 308 Pfam PF01699 Sodium/calcium exchanger protein 8 147 1.7E-18 T 31-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 DFR85_11460 d8919bc1a51d72c3f734cf697362db1c 308 Pfam PF01699 Sodium/calcium exchanger protein 167 304 2.4E-11 T 31-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 DFR85_11460 d8919bc1a51d72c3f734cf697362db1c 308 Gene3D G3DSA:1.20.58.1130 13 196 3.8E-32 T 31-10-2018 DFR85_11460 d8919bc1a51d72c3f734cf697362db1c 308 Gene3D G3DSA:1.20.1420.30 34 296 3.8E-32 T 31-10-2018 DFR85_07375 59f013fbf3241039260f639a59e1b66d 392 Gene3D G3DSA:3.40.50.300 123 303 2.2E-68 T 31-10-2018 DFR85_07375 59f013fbf3241039260f639a59e1b66d 392 SMART SM00382 166 305 3.0E-24 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_07375 59f013fbf3241039260f639a59e1b66d 392 Hamap MF_00553 Proteasome-activating nucleotidase [pan]. 1 391 43.682 T 31-10-2018 IPR023501 Proteasome-activating nucleotidase PAN DFR85_07375 59f013fbf3241039260f639a59e1b66d 392 Gene3D G3DSA:2.40.50.140 19 122 1.2E-24 T 31-10-2018 DFR85_07375 59f013fbf3241039260f639a59e1b66d 392 Gene3D G3DSA:1.10.8.60 304 376 1.7E-24 T 31-10-2018 DFR85_07375 59f013fbf3241039260f639a59e1b66d 392 ProSitePatterns PS00674 AAA-protein family signature. 273 291 - T 31-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 DFR85_07375 59f013fbf3241039260f639a59e1b66d 392 TIGRFAM TIGR01242 26Sp45: 26S proteasome subunit P45 family 16 375 6.5E-171 T 31-10-2018 IPR005937 26S proteasome regulatory subunit P45-like GO:0005737|GO:0016787|GO:0030163 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 DFR85_07375 59f013fbf3241039260f639a59e1b66d 392 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 170 303 2.8E-42 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 DFR85_07375 59f013fbf3241039260f639a59e1b66d 392 SUPERFAMILY SSF52540 128 381 1.73E-74 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_07625 0b065f1b74591096d41df5f30ddbc7cc 404 Gene3D G3DSA:3.40.50.1100 53 149 1.4E-110 T 31-10-2018 DFR85_07625 0b065f1b74591096d41df5f30ddbc7cc 404 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 18 305 5.0E-78 T 31-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme DFR85_07625 0b065f1b74591096d41df5f30ddbc7cc 404 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 24 400 2.1E-139 T 31-10-2018 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 DFR85_07625 0b065f1b74591096d41df5f30ddbc7cc 404 Gene3D G3DSA:3.40.50.1100 12 310 1.4E-110 T 31-10-2018 DFR85_07625 0b065f1b74591096d41df5f30ddbc7cc 404 SUPERFAMILY SSF55021 329 392 1.18E-7 T 31-10-2018 DFR85_07625 0b065f1b74591096d41df5f30ddbc7cc 404 SUPERFAMILY SSF53686 9 317 2.1E-94 T 31-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme DFR85_02765 5e6a2c703c4d023a440d66f6b548ea8e 378 Gene3D G3DSA:3.30.43.10 1 96 3.0E-12 T 31-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 DFR85_02765 5e6a2c703c4d023a440d66f6b548ea8e 378 Gene3D G3DSA:3.40.462.40 200 225 5.5E-9 T 31-10-2018 DFR85_02765 5e6a2c703c4d023a440d66f6b548ea8e 378 SUPERFAMILY SSF56176 14 200 4.02E-26 T 31-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 DFR85_02765 5e6a2c703c4d023a440d66f6b548ea8e 378 Pfam PF01565 FAD binding domain 42 167 1.4E-19 T 31-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 DFR85_02765 5e6a2c703c4d023a440d66f6b548ea8e 378 Gene3D G3DSA:3.30.465.40 126 199 5.5E-9 T 31-10-2018 DFR85_01885 7fc47134efb9584779ae06b31bd38462 156 Pfam PF05942 Archaeal PaREP1/PaREP8 family 45 147 1.7E-9 T 31-10-2018 IPR010268 Archaeal PaREP1 DFR85_00605 66b0dbbbfb2417e9ffe7295b0a6cfc2b 107 ProDom PD005579 INITIATION FACTOR TRANSLATION 1A BIOSYNTHESIS EUKARYOTIC EIF-1A AIF-1A EIF-4C 1A 40 94 3.0E-18 T 31-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 DFR85_00605 66b0dbbbfb2417e9ffe7295b0a6cfc2b 107 TIGRFAM TIGR00523 eIF-1A: translation initiation factor eIF-1A 4 93 4.1E-35 T 31-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 DFR85_00605 66b0dbbbfb2417e9ffe7295b0a6cfc2b 107 SUPERFAMILY SSF50249 3 98 1.66E-31 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR85_00605 66b0dbbbfb2417e9ffe7295b0a6cfc2b 107 SMART SM00652 16 98 2.3E-40 T 31-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 DFR85_00605 66b0dbbbfb2417e9ffe7295b0a6cfc2b 107 Pfam PF01176 Translation initiation factor 1A / IF-1 20 82 2.1E-23 T 31-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 DFR85_00605 66b0dbbbfb2417e9ffe7295b0a6cfc2b 107 ProSitePatterns PS01262 Eukaryotic initiation factor 1A signature. 29 51 - T 31-10-2018 IPR018104 Translation initiation factor 1A (eIF-1A), conserved site GO:0003743|GO:0006413 DFR85_00605 66b0dbbbfb2417e9ffe7295b0a6cfc2b 107 Hamap MF_00216 Translation initiation factor 1A [eif1a]. 5 98 26.58 T 31-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 DFR85_00605 66b0dbbbfb2417e9ffe7295b0a6cfc2b 107 Gene3D G3DSA:2.40.50.140 2 105 3.6E-34 T 31-10-2018 DFR85_07680 d3ef30e870ece61f55ae277256afd028 212 Gene3D G3DSA:3.40.430.10 1 211 5.1E-42 T 31-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 DFR85_07680 d3ef30e870ece61f55ae277256afd028 212 Pfam PF01872 RibD C-terminal domain 4 206 4.5E-40 T 31-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 DFR85_07680 d3ef30e870ece61f55ae277256afd028 212 SUPERFAMILY SSF53597 1 201 3.8E-40 T 31-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 DFR85_07680 d3ef30e870ece61f55ae277256afd028 212 TIGRFAM TIGR01508 rib_reduct_arch: diaminohydroxyphosphoribosylaminopyrimidine reductase 4 206 1.5E-60 T 31-10-2018 IPR006401 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1-reductase, archaeal GO:0016491|GO:0055114 KEGG: 00740+1.1.1.302|MetaCyc: PWY-6167|MetaCyc: PWY-6168 DFR85_00485 f660d5f54d46d51d4077ccc77d081cd2 363 Gene3D G3DSA:1.20.1250.20 1 166 1.8E-12 T 31-10-2018 DFR85_00485 f660d5f54d46d51d4077ccc77d081cd2 363 Gene3D G3DSA:1.20.1250.20 177 360 5.2E-12 T 31-10-2018 DFR85_00485 f660d5f54d46d51d4077ccc77d081cd2 363 Pfam PF07690 Major Facilitator Superfamily 20 323 5.7E-20 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_00485 f660d5f54d46d51d4077ccc77d081cd2 363 SUPERFAMILY SSF103473 4 358 2.75E-35 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_06745 4c71f077dbf7635d826fe89ed05cb04c 468 SUPERFAMILY SSF51905 103 343 2.16E-7 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_06745 4c71f077dbf7635d826fe89ed05cb04c 468 Gene3D G3DSA:1.10.10.1100 397 460 1.3E-13 T 31-10-2018 DFR85_06745 4c71f077dbf7635d826fe89ed05cb04c 468 Pfam PF04324 BFD-like [2Fe-2S] binding domain 404 453 2.2E-7 T 31-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain DFR85_11655 b98e9a85899d9d5ba81d3fe5adaa63ce 281 Pfam PF00892 EamA-like transporter family 136 266 6.3E-17 T 31-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 DFR85_11655 b98e9a85899d9d5ba81d3fe5adaa63ce 281 Pfam PF00892 EamA-like transporter family 7 125 2.5E-16 T 31-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 DFR85_11655 b98e9a85899d9d5ba81d3fe5adaa63ce 281 SUPERFAMILY SSF103481 171 273 5.75E-7 T 31-10-2018 DFR85_11655 b98e9a85899d9d5ba81d3fe5adaa63ce 281 SUPERFAMILY SSF103481 37 127 8.11E-12 T 31-10-2018 DFR85_11930 e21765ea96f50f05ede9adf29720275b 209 SMART SM00382 29 199 1.2E-11 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_11930 e21765ea96f50f05ede9adf29720275b 209 Gene3D G3DSA:3.40.50.300 3 209 1.1E-43 T 31-10-2018 DFR85_11930 e21765ea96f50f05ede9adf29720275b 209 Pfam PF00005 ABC transporter 22 155 6.1E-22 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR85_11930 e21765ea96f50f05ede9adf29720275b 209 SUPERFAMILY SSF52540 5 203 6.92E-42 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_14815 9229ea80ef1d06a882ccefe0a07985e0 208 Pfam PF00753 Metallo-beta-lactamase superfamily 9 186 1.9E-15 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR85_14815 9229ea80ef1d06a882ccefe0a07985e0 208 Gene3D G3DSA:3.60.15.10 1 205 4.0E-53 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR85_14815 9229ea80ef1d06a882ccefe0a07985e0 208 SMART SM00849 12 186 1.7E-34 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR85_14815 9229ea80ef1d06a882ccefe0a07985e0 208 SUPERFAMILY SSF56281 1 203 1.4E-44 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR85_03660 bc39a71b173a961cc58d932aecf932d1 250 Pfam PF07690 Major Facilitator Superfamily 12 237 7.2E-10 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_03660 bc39a71b173a961cc58d932aecf932d1 250 SUPERFAMILY SSF103473 10 238 8.72E-16 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_03660 bc39a71b173a961cc58d932aecf932d1 250 Gene3D G3DSA:1.20.1250.20 6 202 3.3E-12 T 31-10-2018 DFR85_01155 b4765f38d9c763be86f4db38acad5c17 362 Pfam PF00107 Zinc-binding dehydrogenase 193 312 5.6E-26 T 31-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DFR85_01155 b4765f38d9c763be86f4db38acad5c17 362 Gene3D G3DSA:3.40.50.720 171 306 8.1E-117 T 31-10-2018 DFR85_01155 b4765f38d9c763be86f4db38acad5c17 362 Gene3D G3DSA:3.90.180.10 6 356 8.1E-117 T 31-10-2018 DFR85_01155 b4765f38d9c763be86f4db38acad5c17 362 SUPERFAMILY SSF51735 155 326 6.69E-46 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_01155 b4765f38d9c763be86f4db38acad5c17 362 SUPERFAMILY SSF50129 313 359 1.13E-5 T 31-10-2018 IPR011032 GroES-like superfamily DFR85_01155 b4765f38d9c763be86f4db38acad5c17 362 SMART SM00829 14 359 1.8E-6 T 31-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DFR85_01155 b4765f38d9c763be86f4db38acad5c17 362 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 31-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 DFR85_01155 b4765f38d9c763be86f4db38acad5c17 362 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 149 2.3E-28 T 31-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DFR85_01155 b4765f38d9c763be86f4db38acad5c17 362 SUPERFAMILY SSF50129 1 188 3.98E-56 T 31-10-2018 IPR011032 GroES-like superfamily DFR85_12865 b3bbe045cd5cc262f6e18ff22d092588 329 Gene3D G3DSA:2.130.10.10 142 318 1.1E-13 T 31-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 DFR85_12865 b3bbe045cd5cc262f6e18ff22d092588 329 SUPERFAMILY SSF50969 60 308 4.79E-22 T 31-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like DFR85_06490 f2fa09e1a2a2bc4d8f1c0c53512d55e1 198 Pfam PF03458 UPF0126 domain 89 161 1.1E-20 T 31-10-2018 IPR005115 Uncharacterised domain UPF0126 DFR85_06490 f2fa09e1a2a2bc4d8f1c0c53512d55e1 198 Pfam PF03458 UPF0126 domain 3 76 1.4E-17 T 31-10-2018 IPR005115 Uncharacterised domain UPF0126 DFR85_15670 6ff2fe2c6f4f7ce3919de0765f46bb7f 306 SUPERFAMILY SSF53474 43 303 5.2E-68 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold DFR85_15670 6ff2fe2c6f4f7ce3919de0765f46bb7f 306 Gene3D G3DSA:3.40.50.1820 1 305 1.0E-86 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold DFR85_15670 6ff2fe2c6f4f7ce3919de0765f46bb7f 306 Pfam PF07859 alpha/beta hydrolase fold 77 282 7.2E-69 T 31-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 DFR85_02770 111efeb40a39f194d793a8ff513ff552 405 SUPERFAMILY SSF51556 46 365 1.2E-59 T 31-10-2018 IPR032466 Metal-dependent hydrolase DFR85_02770 111efeb40a39f194d793a8ff513ff552 405 Gene3D G3DSA:2.30.40.10 12 397 2.6E-94 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR85_02770 111efeb40a39f194d793a8ff513ff552 405 Gene3D G3DSA:3.20.20.140 46 354 2.6E-94 T 31-10-2018 DFR85_02770 111efeb40a39f194d793a8ff513ff552 405 Pfam PF07969 Amidohydrolase family 162 395 1.9E-17 T 31-10-2018 IPR013108 Amidohydrolase 3 DFR85_02770 111efeb40a39f194d793a8ff513ff552 405 SUPERFAMILY SSF51338 1 57 2.28E-8 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 DFR85_09635 2f0c278d3bf12f23fb92b117bff4d0c9 161 Gene3D G3DSA:3.40.50.150 2 161 3.7E-53 T 31-10-2018 DFR85_09635 2f0c278d3bf12f23fb92b117bff4d0c9 161 SUPERFAMILY SSF53335 7 157 1.15E-33 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR85_09635 2f0c278d3bf12f23fb92b117bff4d0c9 161 Pfam PF13847 Methyltransferase domain 30 145 2.1E-11 T 31-10-2018 IPR025714 Methyltransferase domain DFR85_03155 943548dec676aa9ed81b9a801fd352d3 272 Pfam PF01435 Peptidase family M48 73 261 8.0E-23 T 31-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 DFR85_03155 943548dec676aa9ed81b9a801fd352d3 272 Gene3D G3DSA:3.30.2010.10 58 146 7.9E-16 T 31-10-2018 DFR85_05580 1fee14fdc2b1dcaa98f25f22f1cd4595 328 Pfam PF02361 Cobalt transport protein 55 287 1.5E-14 T 31-10-2018 IPR003339 ABC/ECF transporter, transmembrane component DFR85_01780 f9dc8dff181e717c32af87b30df60313 411 Gene3D G3DSA:3.40.50.2000 3 380 1.2E-130 T 31-10-2018 DFR85_01780 f9dc8dff181e717c32af87b30df60313 411 Gene3D G3DSA:3.40.50.2000 185 379 1.2E-130 T 31-10-2018 DFR85_01780 f9dc8dff181e717c32af87b30df60313 411 Pfam PF00534 Glycosyl transferases group 1 206 372 4.4E-22 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 DFR85_01780 f9dc8dff181e717c32af87b30df60313 411 SUPERFAMILY SSF53756 29 390 2.59E-42 T 31-10-2018 DFR85_12120 6cd01e41067f390446d09b7e337e5c80 209 SUPERFAMILY SSF46785 143 207 1.08E-10 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_12120 6cd01e41067f390446d09b7e337e5c80 209 Gene3D G3DSA:3.40.50.11700 2 138 5.6E-10 T 31-10-2018 DFR85_12120 6cd01e41067f390446d09b7e337e5c80 209 Gene3D G3DSA:1.10.10.10 142 209 1.3E-8 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_12120 6cd01e41067f390446d09b7e337e5c80 209 TIGRFAM TIGR01884 cas_HTH: CRISPR locus-related DNA-binding protein 4 196 8.4E-21 T 31-10-2018 IPR010163 CRISPR locus-related putative DNA-binding protein Csa3 DFR85_12120 6cd01e41067f390446d09b7e337e5c80 209 Pfam PF14947 Winged helix-turn-helix 146 208 7.8E-6 T 31-10-2018 IPR038723 ArnR1-like, winged helix-turn-helix domain DFR85_13655 55b0acd0e5e977c2c01213af38cf3b97 364 Gene3D G3DSA:1.20.1250.20 181 364 1.2E-16 T 31-10-2018 DFR85_13655 55b0acd0e5e977c2c01213af38cf3b97 364 SUPERFAMILY SSF103473 3 363 1.83E-39 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_13655 55b0acd0e5e977c2c01213af38cf3b97 364 Gene3D G3DSA:1.20.1250.20 2 180 7.1E-16 T 31-10-2018 DFR85_13655 55b0acd0e5e977c2c01213af38cf3b97 364 Pfam PF07690 Major Facilitator Superfamily 15 332 8.8E-27 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_10115 090e9807a89a067ce5996cfd2127c163 384 SUPERFAMILY SSF51690 112 382 5.59E-73 T 31-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 DFR85_10115 090e9807a89a067ce5996cfd2127c163 384 SUPERFAMILY SSF54675 2 115 1.43E-32 T 31-10-2018 DFR85_10115 090e9807a89a067ce5996cfd2127c163 384 Gene3D G3DSA:3.20.20.70 107 296 9.0E-61 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_10115 090e9807a89a067ce5996cfd2127c163 384 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 115 301 1.4E-18 T 31-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 DFR85_10115 090e9807a89a067ce5996cfd2127c163 384 Gene3D G3DSA:3.90.1170.20 1 106 4.3E-37 T 31-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 DFR85_10115 090e9807a89a067ce5996cfd2127c163 384 PIRSF PIRSF000484 57 384 5.8E-59 T 31-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 DFR85_10115 090e9807a89a067ce5996cfd2127c163 384 PIRSF PIRSF000484 8 69 22.0 T 31-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 DFR85_02635 f5c9a237c469e7c67558b4af9e9efa65 133 Gene3D G3DSA:3.40.50.1010 4 131 6.5E-12 T 31-10-2018 DFR85_02635 f5c9a237c469e7c67558b4af9e9efa65 133 SUPERFAMILY SSF88723 4 123 1.35E-14 T 31-10-2018 IPR029060 PIN-like domain superfamily DFR85_02635 f5c9a237c469e7c67558b4af9e9efa65 133 Pfam PF01850 PIN domain 5 124 2.1E-13 T 31-10-2018 IPR002716 PIN domain DFR85_05500 94f76265490c3f365c3de6f757027c8c 300 SUPERFAMILY SSF53448 3 259 7.76E-13 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_05500 94f76265490c3f365c3de6f757027c8c 300 Gene3D G3DSA:3.90.550.10 2 231 1.9E-13 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_05500 94f76265490c3f365c3de6f757027c8c 300 Pfam PF00535 Glycosyl transferase family 2 53 136 4.6E-5 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 DFR85_00060 3633165d8ce7fafc1d55c1e18011aeb4 144 Pfam PF02915 Rubrerythrin 11 136 8.7E-26 T 31-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 DFR85_00060 3633165d8ce7fafc1d55c1e18011aeb4 144 Gene3D G3DSA:1.20.1260.10 1 143 3.9E-48 T 31-10-2018 IPR012347 Ferritin-like DFR85_00060 3633165d8ce7fafc1d55c1e18011aeb4 144 SUPERFAMILY SSF47240 4 142 7.92E-38 T 31-10-2018 IPR009078 Ferritin-like superfamily DFR85_05720 2769409ebcbd64ca9c4df9327da1d8aa 242 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 128 196 2.0E-5 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 DFR85_05720 2769409ebcbd64ca9c4df9327da1d8aa 242 Gene3D G3DSA:3.40.50.300 51 209 6.3E-19 T 31-10-2018 DFR85_05720 2769409ebcbd64ca9c4df9327da1d8aa 242 SUPERFAMILY SSF52540 89 233 7.03E-16 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_14150 8d241bc1e74c9038cb3609f0322092a9 90 Gene3D G3DSA:2.40.50.970 1 74 1.5E-24 T 31-10-2018 IPR037254 HupF/HypC superfamily DFR85_14150 8d241bc1e74c9038cb3609f0322092a9 90 SUPERFAMILY SSF159127 1 78 1.29E-21 T 31-10-2018 IPR037254 HupF/HypC superfamily DFR85_14150 8d241bc1e74c9038cb3609f0322092a9 90 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 1 77 1.0E-22 T 31-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC DFR85_14150 8d241bc1e74c9038cb3609f0322092a9 90 Pfam PF01455 HupF/HypC family 1 66 2.3E-23 T 31-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC DFR85_04235 83cc22416951bacd531ac3d910a42a80 505 Pfam PF13520 Amino acid permease 10 383 7.7E-28 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_04235 83cc22416951bacd531ac3d910a42a80 505 Gene3D G3DSA:1.20.1740.10 3 474 5.6E-21 T 31-10-2018 DFR85_04235 83cc22416951bacd531ac3d910a42a80 505 PIRSF PIRSF006060 1 477 1.1E-39 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_13695 059eb50112864d2d7210397ab5cb230c 125 Pfam PF14947 Winged helix-turn-helix 34 106 5.6E-21 T 31-10-2018 IPR038723 ArnR1-like, winged helix-turn-helix domain DFR85_13695 059eb50112864d2d7210397ab5cb230c 125 Gene3D G3DSA:1.10.10.10 32 123 1.6E-21 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_13695 059eb50112864d2d7210397ab5cb230c 125 SUPERFAMILY SSF46785 38 116 5.19E-14 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_14190 97cbcb1a9c4aff2f640a7041022aea1c 366 SUPERFAMILY SSF63829 154 319 1.96E-11 T 31-10-2018 DFR85_14190 97cbcb1a9c4aff2f640a7041022aea1c 366 Gene3D G3DSA:2.130.10.10 191 333 1.8E-7 T 31-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 DFR85_11850 381c1ba5929a0a288d481b73d43d8a96 127 SUPERFAMILY SSF54631 3 123 1.05E-27 T 31-10-2018 DFR85_11850 381c1ba5929a0a288d481b73d43d8a96 127 Pfam PF00571 CBS domain 77 121 2.8E-6 T 31-10-2018 IPR000644 CBS domain DFR85_11850 381c1ba5929a0a288d481b73d43d8a96 127 Pfam PF00571 CBS domain 4 58 3.9E-12 T 31-10-2018 IPR000644 CBS domain DFR85_11850 381c1ba5929a0a288d481b73d43d8a96 127 SMART SM00116 75 123 0.0085 T 31-10-2018 IPR000644 CBS domain DFR85_11850 381c1ba5929a0a288d481b73d43d8a96 127 SMART SM00116 11 58 5.4E-9 T 31-10-2018 IPR000644 CBS domain DFR85_11850 381c1ba5929a0a288d481b73d43d8a96 127 Gene3D G3DSA:3.10.580.10 1 126 7.8E-30 T 31-10-2018 DFR85_04350 aabbb4f56d6f449b68ac27140ad0db93 345 SUPERFAMILY SSF53756 7 344 4.93E-37 T 31-10-2018 DFR85_04350 aabbb4f56d6f449b68ac27140ad0db93 345 Gene3D G3DSA:3.40.50.2000 167 326 1.6E-25 T 31-10-2018 DFR85_04350 aabbb4f56d6f449b68ac27140ad0db93 345 Pfam PF00534 Glycosyl transferases group 1 176 323 2.7E-17 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 DFR85_09950 9427f9e4649adea570ae1c5c70acf980 313 Gene3D G3DSA:3.30.70.890 175 284 9.4E-68 T 31-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily DFR85_09950 9427f9e4649adea570ae1c5c70acf980 313 PRINTS PR00959 Mevalonate kinase family signature 266 283 8.6E-13 T 31-10-2018 DFR85_09950 9427f9e4649adea570ae1c5c70acf980 313 PRINTS PR00959 Mevalonate kinase family signature 95 117 8.6E-13 T 31-10-2018 DFR85_09950 9427f9e4649adea570ae1c5c70acf980 313 PRINTS PR00959 Mevalonate kinase family signature 6 30 8.6E-13 T 31-10-2018 DFR85_09950 9427f9e4649adea570ae1c5c70acf980 313 Hamap MF_00217 Mevalonate kinase [mvk]. 2 307 50.659 T 31-10-2018 IPR022937 Mevalonate kinase, archaeal GO:0004496 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922 DFR85_09950 9427f9e4649adea570ae1c5c70acf980 313 Pfam PF00288 GHMP kinases N terminal domain 91 157 3.7E-10 T 31-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 DFR85_09950 9427f9e4649adea570ae1c5c70acf980 313 SUPERFAMILY SSF55060 174 309 2.67E-23 T 31-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily DFR85_09950 9427f9e4649adea570ae1c5c70acf980 313 Pfam PF08544 GHMP kinases C terminal 222 280 3.5E-9 T 31-10-2018 IPR013750 GHMP kinase, C-terminal domain DFR85_09950 9427f9e4649adea570ae1c5c70acf980 313 Gene3D G3DSA:3.30.230.10 7 174 9.4E-68 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup DFR85_09950 9427f9e4649adea570ae1c5c70acf980 313 TIGRFAM TIGR00549 mevalon_kin: mevalonate kinase 7 280 4.3E-73 T 31-10-2018 IPR006205 Mevalonate kinase GO:0004496|GO:0005524|GO:0005737|GO:0008299 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168 DFR85_09950 9427f9e4649adea570ae1c5c70acf980 313 SUPERFAMILY SSF54211 1 175 2.13E-33 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold DFR85_01990 5f9787854caaeabb391afc9b2515e3d9 46 Pfam PF06143 Baculovirus 11 kDa family 4 39 3.3E-5 T 31-10-2018 IPR009313 Baculovirus 11kDa DFR85_09050 c5258958cac63fd41bd056eed13b951f 199 Gene3D G3DSA:3.90.550.10 15 195 1.5E-24 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_09050 c5258958cac63fd41bd056eed13b951f 199 Pfam PF12804 MobA-like NTP transferase domain 16 128 6.2E-14 T 31-10-2018 IPR025877 MobA-like NTP transferase DFR85_09050 c5258958cac63fd41bd056eed13b951f 199 SUPERFAMILY SSF53448 15 184 1.53E-16 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_04295 24239a7d4645ab4b37b844c1e2916669 340 Pfam PF00535 Glycosyl transferase family 2 5 139 6.1E-18 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 DFR85_04295 24239a7d4645ab4b37b844c1e2916669 340 SUPERFAMILY SSF53448 2 219 5.22E-37 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_04295 24239a7d4645ab4b37b844c1e2916669 340 Gene3D G3DSA:3.90.550.10 1 260 1.8E-29 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_02835 285e175d600cc1223687c1699f77b944 422 Gene3D G3DSA:1.20.1250.20 5 420 3.1E-40 T 31-10-2018 DFR85_02835 285e175d600cc1223687c1699f77b944 422 SUPERFAMILY SSF103473 7 416 1.7E-48 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_02835 285e175d600cc1223687c1699f77b944 422 Pfam PF07690 Major Facilitator Superfamily 28 370 1.4E-19 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_04860 9ac933d77ac3fa21abdf0b1d0cd3add2 307 TIGRFAM TIGR01888 cas_cmr3: CRISPR type III-B/RAMP module-associated protein Cmr3 7 305 1.7E-30 T 31-10-2018 IPR010165 CRISPR-associated protein, TM1793 DFR85_11715 61dc25cf41e5e0e6ea133adacaf50f68 147 SUPERFAMILY SSF55186 2 143 2.49E-30 T 31-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 DFR85_11715 61dc25cf41e5e0e6ea133adacaf50f68 147 Gene3D G3DSA:3.30.54.20 68 114 1.8E-47 T 31-10-2018 DFR85_11715 61dc25cf41e5e0e6ea133adacaf50f68 147 Gene3D G3DSA:3.30.980.10 5 143 1.8E-47 T 31-10-2018 DFR85_07000 f08a121ba4a41c65c17f06729666a0b6 156 SUPERFAMILY SSF55129 6 156 2.22E-34 T 31-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily DFR85_07000 f08a121ba4a41c65c17f06729666a0b6 156 Pfam PF00327 Ribosomal protein L30p/L7e 8 55 1.2E-12 T 31-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain DFR85_07000 f08a121ba4a41c65c17f06729666a0b6 156 Hamap MF_01371_A 50S ribosomal protein L30 [rpmD]. 1 156 52.357 T 31-10-2018 IPR005997 Ribosomal protein L30, archaeal GO:0003735|GO:0006412|GO:0015934 DFR85_07000 f08a121ba4a41c65c17f06729666a0b6 156 Gene3D G3DSA:3.30.1390.20 8 144 1.1E-38 T 31-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily DFR85_07000 f08a121ba4a41c65c17f06729666a0b6 156 TIGRFAM TIGR01309 uL30_arch: ribosomal protein uL30 8 156 2.2E-45 T 31-10-2018 IPR005997 Ribosomal protein L30, archaeal GO:0003735|GO:0006412|GO:0015934 DFR85_07000 f08a121ba4a41c65c17f06729666a0b6 156 Gene3D G3DSA:1.10.15.30 61 115 1.1E-38 T 31-10-2018 IPR023106 Ribosomal protein L30, central domain, archaeal type DFR85_07235 38f7ec190cf6ae65550789e9123aa1a4 203 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 106 112 - T 31-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 DFR85_07235 38f7ec190cf6ae65550789e9123aa1a4 203 Pfam PF05175 Methyltransferase small domain 27 112 5.4E-12 T 31-10-2018 IPR007848 Methyltransferase small domain GO:0008168 DFR85_07235 38f7ec190cf6ae65550789e9123aa1a4 203 SUPERFAMILY SSF53335 6 172 8.44E-27 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR85_07235 38f7ec190cf6ae65550789e9123aa1a4 203 TIGRFAM TIGR00537 hemK_rel_arch: putative methylase 20 189 2.3E-38 T 31-10-2018 IPR004557 Eukaryotic/archaeal PrmC-related GO:0008276 Reactome: R-HSA-156581|Reactome: R-HSA-72764 DFR85_07235 38f7ec190cf6ae65550789e9123aa1a4 203 Gene3D G3DSA:3.40.50.150 18 196 4.2E-31 T 31-10-2018 DFR85_04305 90cfb559d4fc737d632d62783995fcf2 361 Gene3D G3DSA:3.40.50.2000 195 356 1.2E-18 T 31-10-2018 DFR85_04305 90cfb559d4fc737d632d62783995fcf2 361 Pfam PF00534 Glycosyl transferases group 1 242 328 4.9E-13 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 DFR85_04305 90cfb559d4fc737d632d62783995fcf2 361 SUPERFAMILY SSF53756 5 356 1.57E-32 T 31-10-2018 DFR85_12920 f36acb35dc3c54f690d180eea8668063 200 Pfam PF00753 Metallo-beta-lactamase superfamily 11 193 2.1E-21 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR85_12920 f36acb35dc3c54f690d180eea8668063 200 SUPERFAMILY SSF56281 13 198 5.5E-37 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR85_12920 f36acb35dc3c54f690d180eea8668063 200 Gene3D G3DSA:3.60.15.10 1 199 1.3E-39 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR85_12920 f36acb35dc3c54f690d180eea8668063 200 SMART SM00849 10 193 7.0E-24 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR85_15505 26f116acfb77e9c5eeb69710ec38ee8b 183 Pfam PF05977 Transmembrane secretion effector 10 135 6.8E-7 T 31-10-2018 IPR010290 Transmembrane secretion effector DFR85_15505 26f116acfb77e9c5eeb69710ec38ee8b 183 Gene3D G3DSA:1.20.1250.20 4 181 2.8E-6 T 31-10-2018 DFR85_15505 26f116acfb77e9c5eeb69710ec38ee8b 183 SUPERFAMILY SSF103473 3 171 6.54E-10 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_12295 264f07985c9442bea577995be718e534 379 Pfam PF01136 Peptidase family U32 85 149 4.8E-9 T 31-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 DFR85_01995 cca59aca359aba8fd6e5a6935a4ad723 170 Pfam PF08394 Archaeal TRASH domain 129 165 3.3E-16 T 31-10-2018 IPR013603 TRASH transcription regulator C-terminal, archaeal DFR85_01995 cca59aca359aba8fd6e5a6935a4ad723 170 Pfam PF13412 Winged helix-turn-helix DNA-binding 10 55 7.6E-11 T 31-10-2018 DFR85_01995 cca59aca359aba8fd6e5a6935a4ad723 170 Gene3D G3DSA:1.10.10.10 1 59 1.3E-13 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_01995 cca59aca359aba8fd6e5a6935a4ad723 170 SMART SM00746 129 165 6.2E-6 T 31-10-2018 IPR011017 TRASH domain DFR85_01995 cca59aca359aba8fd6e5a6935a4ad723 170 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 10 26 3.7E-7 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR85_01995 cca59aca359aba8fd6e5a6935a4ad723 170 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 37 56 3.7E-7 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR85_01995 cca59aca359aba8fd6e5a6935a4ad723 170 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 26 37 3.7E-7 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR85_01995 cca59aca359aba8fd6e5a6935a4ad723 170 SUPERFAMILY SSF46785 6 55 6.25E-10 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_05930 6b5e419b3870c6ce72203dbe05b0e153 286 SUPERFAMILY SSF52540 12 234 1.72E-25 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_05930 6b5e419b3870c6ce72203dbe05b0e153 286 Gene3D G3DSA:3.40.50.300 8 285 3.3E-37 T 31-10-2018 DFR85_05930 6b5e419b3870c6ce72203dbe05b0e153 286 Pfam PF00005 ABC transporter 17 162 2.0E-6 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR85_06065 f1ac3049a4c9cbba67f0aaf49f118ed8 546 Pfam PF09843 Predicted membrane protein (DUF2070) 25 533 2.2E-92 T 31-10-2018 IPR019204 Domain of unknown function DUF2070, membrane DFR85_10090 3d920e798b9709d94dbab147766bb923 294 Gene3D G3DSA:3.40.50.1100 21 284 2.2E-66 T 31-10-2018 DFR85_10090 3d920e798b9709d94dbab147766bb923 294 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 17 277 9.6E-51 T 31-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme DFR85_10090 3d920e798b9709d94dbab147766bb923 294 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 35 54 - T 31-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 DFR85_10090 3d920e798b9709d94dbab147766bb923 294 SUPERFAMILY SSF53686 14 291 1.57E-66 T 31-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme DFR85_10090 3d920e798b9709d94dbab147766bb923 294 Gene3D G3DSA:3.40.50.1100 49 144 2.2E-66 T 31-10-2018 DFR85_01270 77836efc3406ca0560f989bf39ff458b 201 SUPERFAMILY SSF53335 29 166 1.47E-11 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR85_01270 77836efc3406ca0560f989bf39ff458b 201 Pfam PF08241 Methyltransferase domain 37 112 1.3E-8 T 31-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 DFR85_01270 77836efc3406ca0560f989bf39ff458b 201 Gene3D G3DSA:3.40.50.150 5 197 1.0E-17 T 31-10-2018 DFR85_04355 440cc1d98d64f112edcf0333b3910594 398 Pfam PF00534 Glycosyl transferases group 1 215 373 4.0E-21 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 DFR85_04355 440cc1d98d64f112edcf0333b3910594 398 Gene3D G3DSA:3.40.50.2000 204 380 4.4E-27 T 31-10-2018 DFR85_04355 440cc1d98d64f112edcf0333b3910594 398 Pfam PF13439 Glycosyltransferase Family 4 24 194 3.1E-7 T 31-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 DFR85_04355 440cc1d98d64f112edcf0333b3910594 398 SUPERFAMILY SSF53756 20 396 2.87E-47 T 31-10-2018 DFR85_04355 440cc1d98d64f112edcf0333b3910594 398 Gene3D G3DSA:3.40.50.2000 1 203 2.1E-8 T 31-10-2018 DFR85_12500 0ccc065fde662ef2280a39ec4bcd9574 429 Gene3D G3DSA:3.10.20.70 8 96 1.9E-8 T 31-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DFR85_12500 0ccc065fde662ef2280a39ec4bcd9574 429 SMART SM01230 102 347 7.3E-94 T 31-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DFR85_12500 0ccc065fde662ef2280a39ec4bcd9574 429 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 223 238 - T 31-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 DFR85_12500 0ccc065fde662ef2280a39ec4bcd9574 429 Pfam PF16952 Glutamine synthetase N-terminal domain 6 97 1.4E-9 T 31-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 DFR85_12500 0ccc065fde662ef2280a39ec4bcd9574 429 SUPERFAMILY SSF55931 103 426 8.24E-101 T 31-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 DFR85_12500 0ccc065fde662ef2280a39ec4bcd9574 429 SUPERFAMILY SSF54368 4 99 1.05E-10 T 31-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DFR85_12500 0ccc065fde662ef2280a39ec4bcd9574 429 Pfam PF00120 Glutamine synthetase, catalytic domain 103 426 3.5E-102 T 31-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 DFR85_12500 0ccc065fde662ef2280a39ec4bcd9574 429 Gene3D G3DSA:3.30.590.10 106 428 2.0E-108 T 31-10-2018 DFR85_12640 b0a5348b5f2bcd255001d8b4402e7afd 386 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 3 383 1.9E-122 T 31-10-2018 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 DFR85_08740 54db0161a9b69b7880cc2d568cd90096 393 Pfam PF01966 HD domain 50 164 5.3E-9 T 31-10-2018 IPR006674 HD domain DFR85_08740 54db0161a9b69b7880cc2d568cd90096 393 SUPERFAMILY SSF109604 1 390 1.52E-83 T 31-10-2018 DFR85_08740 54db0161a9b69b7880cc2d568cd90096 393 Gene3D G3DSA:1.10.3210.10 1 289 3.7E-76 T 31-10-2018 DFR85_08740 54db0161a9b69b7880cc2d568cd90096 393 SMART SM00471 46 173 1.7E-10 T 31-10-2018 IPR003607 HD/PDEase domain DFR85_01115 3ca79ac51711c2c09701adcdd8fc0102 565 Gene3D G3DSA:3.40.50.2000 15 300 3.3E-33 T 31-10-2018 DFR85_01115 3ca79ac51711c2c09701adcdd8fc0102 565 Gene3D G3DSA:3.40.50.2000 309 503 6.1E-38 T 31-10-2018 DFR85_01115 3ca79ac51711c2c09701adcdd8fc0102 565 Pfam PF00534 Glycosyl transferases group 1 344 494 9.2E-28 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 DFR85_01115 3ca79ac51711c2c09701adcdd8fc0102 565 Pfam PF08323 Starch synthase catalytic domain 15 255 5.3E-29 T 31-10-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 DFR85_01115 3ca79ac51711c2c09701adcdd8fc0102 565 SUPERFAMILY SSF53756 15 552 1.5E-63 T 31-10-2018 DFR85_08100 c5546b889eaae5651ca621401655a682 100 TIGRFAM TIGR01158 SUI1_rel: putative translation initiation factor SUI1 6 96 1.4E-36 T 31-10-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 DFR85_08100 c5546b889eaae5651ca621401655a682 100 Pfam PF01253 Translation initiation factor SUI1 22 92 2.2E-22 T 31-10-2018 IPR001950 SUI1 domain GO:0003743|GO:0006413 DFR85_08100 c5546b889eaae5651ca621401655a682 100 Gene3D G3DSA:3.30.780.10 21 99 2.7E-30 T 31-10-2018 DFR85_08100 c5546b889eaae5651ca621401655a682 100 PIRSF PIRSF037511 4 98 2.3E-28 T 31-10-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 DFR85_08100 c5546b889eaae5651ca621401655a682 100 Hamap MF_00604 Protein translation factor SUI1 homolog. 5 94 25.921 T 31-10-2018 IPR022851 Translation factor SUI1 homolog, archaea DFR85_08100 c5546b889eaae5651ca621401655a682 100 SUPERFAMILY SSF55159 17 97 6.54E-26 T 31-10-2018 IPR036877 SUI1 domain superfamily GO:0003743|GO:0006413 DFR85_01285 ccac67c20eab97e4fed25bf18c5abcb5 98 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 4 97 3.7E-22 T 31-10-2018 IPR002767 Thiamine-binding protein DFR85_01285 ccac67c20eab97e4fed25bf18c5abcb5 98 Pfam PF01910 Thiamine-binding protein 5 95 1.8E-23 T 31-10-2018 IPR002767 Thiamine-binding protein DFR85_01285 ccac67c20eab97e4fed25bf18c5abcb5 98 SUPERFAMILY SSF89957 1 97 1.19E-22 T 31-10-2018 IPR029756 MTH1187/YkoF-like DFR85_01285 ccac67c20eab97e4fed25bf18c5abcb5 98 Gene3D G3DSA:3.30.70.930 1 98 4.5E-24 T 31-10-2018 IPR029756 MTH1187/YkoF-like DFR85_10425 1a20fdd02b94ed7a7a2187b5f4b2dcef 250 Gene3D G3DSA:3.40.50.10900 1 241 1.1E-51 T 31-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily DFR85_10425 1a20fdd02b94ed7a7a2187b5f4b2dcef 250 SUPERFAMILY SSF159659 3 236 4.18E-44 T 31-10-2018 DFR85_10425 1a20fdd02b94ed7a7a2187b5f4b2dcef 250 Pfam PF09754 PAC2 family 22 229 1.6E-41 T 31-10-2018 IPR019151 Proteasome assembly chaperone 2 DFR85_15385 5aca85122eec2f98088601f6a60fee74 256 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 254 2.2E-80 T 31-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 DFR85_15385 5aca85122eec2f98088601f6a60fee74 256 Gene3D G3DSA:3.90.226.10 1 197 7.6E-73 T 31-10-2018 DFR85_15385 5aca85122eec2f98088601f6a60fee74 256 Gene3D G3DSA:1.10.12.10 199 254 1.5E-18 T 31-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal DFR85_15385 5aca85122eec2f98088601f6a60fee74 256 SUPERFAMILY SSF52096 1 254 1.66E-88 T 31-10-2018 IPR029045 ClpP/crotonase-like domain superfamily DFR85_15385 5aca85122eec2f98088601f6a60fee74 256 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 96 116 - T 31-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 DFR85_06250 dda19b335c4f5ec276988e445f1bb76d 384 Pfam PF07690 Major Facilitator Superfamily 16 250 5.6E-14 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_06250 dda19b335c4f5ec276988e445f1bb76d 384 SUPERFAMILY SSF103473 11 379 7.98E-35 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_06250 dda19b335c4f5ec276988e445f1bb76d 384 Gene3D G3DSA:1.20.1250.20 265 380 5.0E-12 T 31-10-2018 DFR85_06250 dda19b335c4f5ec276988e445f1bb76d 384 Gene3D G3DSA:1.20.1250.20 2 264 1.4E-16 T 31-10-2018 DFR85_11785 2ed7cffcb29eab65a9ec54a2ec7d4336 260 SUPERFAMILY SSF56281 20 226 3.66E-26 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR85_11785 2ed7cffcb29eab65a9ec54a2ec7d4336 260 Pfam PF00753 Metallo-beta-lactamase superfamily 42 169 1.2E-6 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR85_11785 2ed7cffcb29eab65a9ec54a2ec7d4336 260 SMART SM00849 11 176 5.0E-17 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR85_11785 2ed7cffcb29eab65a9ec54a2ec7d4336 260 Gene3D G3DSA:3.60.15.10 10 199 3.0E-23 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR85_15220 7cb9d243bbc84cc400c6ae6d266ad79e 286 SMART SM00382 33 192 3.6E-7 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_15220 7cb9d243bbc84cc400c6ae6d266ad79e 286 SUPERFAMILY SSF52540 29 222 1.5E-35 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_15220 7cb9d243bbc84cc400c6ae6d266ad79e 286 Gene3D G3DSA:3.40.50.300 20 204 2.5E-33 T 31-10-2018 DFR85_15220 7cb9d243bbc84cc400c6ae6d266ad79e 286 Pfam PF07728 AAA domain (dynein-related subfamily) 37 186 3.3E-13 T 31-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 DFR85_07935 6d7c2bc9d5b876413bf6447f98ac20f9 415 SUPERFAMILY SSF52540 4 205 4.69E-48 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_07935 6d7c2bc9d5b876413bf6447f98ac20f9 415 PRINTS PR00315 GTP-binding elongation factor signature 106 117 1.1E-13 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR85_07935 6d7c2bc9d5b876413bf6447f98ac20f9 415 PRINTS PR00315 GTP-binding elongation factor signature 144 153 1.1E-13 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR85_07935 6d7c2bc9d5b876413bf6447f98ac20f9 415 PRINTS PR00315 GTP-binding elongation factor signature 11 24 1.1E-13 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR85_07935 6d7c2bc9d5b876413bf6447f98ac20f9 415 PRINTS PR00315 GTP-binding elongation factor signature 90 100 1.1E-13 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR85_07935 6d7c2bc9d5b876413bf6447f98ac20f9 415 Gene3D G3DSA:2.40.30.10 208 321 1.3E-41 T 31-10-2018 DFR85_07935 6d7c2bc9d5b876413bf6447f98ac20f9 415 SUPERFAMILY SSF50447 207 317 3.53E-34 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily DFR85_07935 6d7c2bc9d5b876413bf6447f98ac20f9 415 SUPERFAMILY SSF50465 324 414 1.34E-28 T 31-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal DFR85_07935 6d7c2bc9d5b876413bf6447f98ac20f9 415 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 196 7.2E-12 T 31-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 DFR85_07935 6d7c2bc9d5b876413bf6447f98ac20f9 415 Gene3D G3DSA:3.40.50.300 3 207 8.8E-61 T 31-10-2018 DFR85_07935 6d7c2bc9d5b876413bf6447f98ac20f9 415 Hamap MF_00119 Translation initiation factor 2 subunit gamma [eif2g]. 2 414 58.104 T 31-10-2018 IPR022424 Translation initiation factor 2, gamma subunit DFR85_07935 6d7c2bc9d5b876413bf6447f98ac20f9 415 TIGRFAM TIGR03680 eif2g_arch: translation initiation factor 2, gamma subunit 6 413 3.8E-191 T 31-10-2018 IPR022424 Translation initiation factor 2, gamma subunit DFR85_07935 6d7c2bc9d5b876413bf6447f98ac20f9 415 Gene3D G3DSA:2.40.30.10 323 415 1.0E-31 T 31-10-2018 DFR85_07935 6d7c2bc9d5b876413bf6447f98ac20f9 415 Pfam PF09173 Initiation factor eIF2 gamma, C terminal 328 413 3.9E-29 T 31-10-2018 IPR015256 Translation initiation factor 2, gamma subunit, C-terminal DFR85_07935 6d7c2bc9d5b876413bf6447f98ac20f9 415 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 7.6E-30 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 DFR85_12685 988a6e1baf348568c9a0678ba4cf0bd8 287 SUPERFAMILY SSF161098 15 284 3.66E-58 T 31-10-2018 IPR035906 MetI-like superfamily DFR85_12685 988a6e1baf348568c9a0678ba4cf0bd8 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 279 1.5E-15 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 DFR85_12685 988a6e1baf348568c9a0678ba4cf0bd8 287 Gene3D G3DSA:1.10.3720.10 13 279 1.0E-55 T 31-10-2018 IPR035906 MetI-like superfamily DFR85_13475 3fbd370dbece2209f5f6fa74fef73a54 126 Gene3D G3DSA:2.40.70.10 9 123 6.2E-6 T 31-10-2018 IPR021109 Aspartic peptidase domain superfamily DFR85_13475 3fbd370dbece2209f5f6fa74fef73a54 126 TIGRFAM TIGR03698 clan_AA_DTGF: clan AA aspartic protease, AF_0612 family 16 122 4.3E-24 T 31-10-2018 IPR022274 Peptidase aspartic, AF0612 DFR85_06715 2ce9ab23d8f867694c58a9a584efda5a 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 304 323 6.6E-56 T 31-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 DFR85_06715 2ce9ab23d8f867694c58a9a584efda5a 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 196 215 6.6E-56 T 31-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 DFR85_06715 2ce9ab23d8f867694c58a9a584efda5a 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 248 264 6.6E-56 T 31-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 DFR85_06715 2ce9ab23d8f867694c58a9a584efda5a 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 124 138 6.6E-56 T 31-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 DFR85_06715 2ce9ab23d8f867694c58a9a584efda5a 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 158 177 6.6E-56 T 31-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 DFR85_06715 2ce9ab23d8f867694c58a9a584efda5a 336 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 274 289 6.6E-56 T 31-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 DFR85_06715 2ce9ab23d8f867694c58a9a584efda5a 336 SUPERFAMILY SSF51569 3 332 1.61E-132 T 31-10-2018 DFR85_06715 2ce9ab23d8f867694c58a9a584efda5a 336 Pfam PF00490 Delta-aminolevulinic acid dehydratase 8 329 2.3E-139 T 31-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 DFR85_06715 2ce9ab23d8f867694c58a9a584efda5a 336 SMART SM01004 4 330 4.6E-214 T 31-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 DFR85_06715 2ce9ab23d8f867694c58a9a584efda5a 336 PIRSF PIRSF001415 1 333 1.8E-148 T 31-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 DFR85_06715 2ce9ab23d8f867694c58a9a584efda5a 336 Gene3D G3DSA:3.20.20.70 1 336 4.8E-146 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_06715 2ce9ab23d8f867694c58a9a584efda5a 336 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 248 260 - T 31-10-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 DFR85_05410 1a523ece1733a240c3b6058e0535f0f9 61 Gene3D G3DSA:2.40.50.40 1 61 1.5E-33 T 31-10-2018 DFR85_05410 1a523ece1733a240c3b6058e0535f0f9 61 Pfam PF02294 7kD DNA-binding domain 4 61 1.4E-36 T 31-10-2018 IPR003212 DNA-binding 7kDa protein GO:0003677|GO:0004521 DFR85_05410 1a523ece1733a240c3b6058e0535f0f9 61 SUPERFAMILY SSF54160 3 61 2.06E-30 T 31-10-2018 IPR016197 Chromo-like domain superfamily DFR85_05410 1a523ece1733a240c3b6058e0535f0f9 61 ProDom PD010328 DNA-BINDING METHYLATION DIRECT SEQUENCING 3D-STRUCTURE A 7A 3.1.27.- P2 7D 32 61 1.0E-8 T 31-10-2018 IPR003212 DNA-binding 7kDa protein GO:0003677|GO:0004521 DFR85_03185 a3a9b2bc8b207753e63878833b5381a4 171 Pfam PF05942 Archaeal PaREP1/PaREP8 family 18 133 3.5E-20 T 31-10-2018 IPR010268 Archaeal PaREP1 DFR85_06610 e3b90cc1f7bc57e7c57a4d53164132e4 263 Gene3D G3DSA:3.40.1190.20 4 258 2.1E-33 T 31-10-2018 IPR029056 Ribokinase-like DFR85_06610 e3b90cc1f7bc57e7c57a4d53164132e4 263 SUPERFAMILY SSF53613 2 248 1.6E-14 T 31-10-2018 IPR029056 Ribokinase-like DFR85_03555 3e022278360170acd7e322df3f36d2df 120 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 7 95 1.5E-7 T 31-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 DFR85_03555 3e022278360170acd7e322df3f36d2df 120 SUPERFAMILY SSF81343 10 118 1.33E-10 T 31-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 DFR85_03555 3e022278360170acd7e322df3f36d2df 120 Gene3D G3DSA:1.20.1300.10 8 120 1.9E-7 T 31-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 DFR85_01750 14c34f256c40ca480c69b425c4c82fe1 176 Gene3D G3DSA:3.40.50.10630 14 176 5.7E-33 T 31-10-2018 DFR85_01750 14c34f256c40ca480c69b425c4c82fe1 176 SUPERFAMILY SSF52141 27 174 2.09E-35 T 31-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 DFR85_07145 ec6c0468979311a5605b5cb755dd7895 229 Gene3D G3DSA:1.10.150.20 143 215 1.4E-15 T 31-10-2018 DFR85_07145 ec6c0468979311a5605b5cb755dd7895 229 SMART SM00891 4 84 5.6E-24 T 31-10-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 DFR85_07145 ec6c0468979311a5605b5cb755dd7895 229 Pfam PF02732 ERCC4 domain 8 128 1.3E-23 T 31-10-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 DFR85_07145 ec6c0468979311a5605b5cb755dd7895 229 SUPERFAMILY SSF52980 3 131 1.21E-32 T 31-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 DFR85_07145 ec6c0468979311a5605b5cb755dd7895 229 SUPERFAMILY SSF47781 154 219 2.0E-13 T 31-10-2018 IPR010994 RuvA domain 2-like DFR85_07145 ec6c0468979311a5605b5cb755dd7895 229 Gene3D G3DSA:3.40.50.10130 1 132 1.6E-37 T 31-10-2018 DFR85_11115 a92e366de79d9d807fb71eb6eaef58f8 416 PRINTS PR01466 Bacterial arginine deiminase signature 397 415 8.5E-10 T 31-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 DFR85_11115 a92e366de79d9d807fb71eb6eaef58f8 416 PRINTS PR01466 Bacterial arginine deiminase signature 176 191 8.5E-10 T 31-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 DFR85_11115 a92e366de79d9d807fb71eb6eaef58f8 416 PRINTS PR01466 Bacterial arginine deiminase signature 148 166 8.5E-10 T 31-10-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 DFR85_11115 a92e366de79d9d807fb71eb6eaef58f8 416 Pfam PF02274 Amidinotransferase 16 415 1.6E-44 T 31-10-2018 DFR85_11115 a92e366de79d9d807fb71eb6eaef58f8 416 SUPERFAMILY SSF55909 3 416 1.96E-70 T 31-10-2018 DFR85_08530 6aa2c37d24b3b0f05400b89e3e6b252f 369 Pfam PF07690 Major Facilitator Superfamily 3 328 1.3E-18 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_08530 6aa2c37d24b3b0f05400b89e3e6b252f 369 SUPERFAMILY SSF103473 3 358 3.01E-24 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_08530 6aa2c37d24b3b0f05400b89e3e6b252f 369 Gene3D G3DSA:1.20.1250.20 2 360 6.8E-18 T 31-10-2018 DFR85_10160 f34a2f17f3eb44360d9c6f1138cedb35 59 TIGRFAM TIGR00327 secE_euk_arch: protein translocase SEC61 complex gamma subunit, archaeal and eukaryotic 4 59 9.3E-11 T 31-10-2018 IPR008158 Protein translocase SEC61 complex, gamma subunit GO:0015031|GO:0015450|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 DFR85_10160 f34a2f17f3eb44360d9c6f1138cedb35 59 SUPERFAMILY SSF103456 4 57 1.57E-13 T 31-10-2018 IPR023391 Protein translocase SecE domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 DFR85_10160 f34a2f17f3eb44360d9c6f1138cedb35 59 Gene3D G3DSA:1.20.5.820 1 59 7.0E-12 T 31-10-2018 IPR023391 Protein translocase SecE domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 DFR85_10160 f34a2f17f3eb44360d9c6f1138cedb35 59 Hamap MF_00422 Protein translocase subunit SecE [secE]. 5 58 10.468 T 31-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 DFR85_00980 bd41851336768e447ea640c7f3146192 251 Pfam PF09339 IclR helix-turn-helix domain 193 232 1.6E-5 T 31-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 DFR85_00980 bd41851336768e447ea640c7f3146192 251 Gene3D G3DSA:1.10.10.10 176 235 6.9E-8 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_00980 bd41851336768e447ea640c7f3146192 251 SUPERFAMILY SSF46785 174 240 9.42E-8 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_11990 15a66f2a2740b6edf155a3dd2c9c5efb 344 SUPERFAMILY SSF111283 145 337 3.27E-26 T 31-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 DFR85_11990 15a66f2a2740b6edf155a3dd2c9c5efb 344 Pfam PF01523 Putative modulator of DNA gyrase 145 217 2.0E-13 T 31-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 DFR85_04505 427c5439090f27df0d9c67f3c082ecd8 613 Gene3D G3DSA:1.20.5.450 195 360 4.0E-5 T 31-10-2018 DFR85_15095 b0cf7a6a3c2774d96ef56d3407dcefdd 490 Pfam PF00083 Sugar (and other) transporter 27 461 2.1E-84 T 31-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 DFR85_15095 b0cf7a6a3c2774d96ef56d3407dcefdd 490 SUPERFAMILY SSF103473 11 456 3.27E-59 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_15095 b0cf7a6a3c2774d96ef56d3407dcefdd 490 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 12 457 1.4E-78 T 31-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 DFR85_15095 b0cf7a6a3c2774d96ef56d3407dcefdd 490 ProSitePatterns PS00216 Sugar transport proteins signature 1. 322 338 - T 31-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DFR85_15095 b0cf7a6a3c2774d96ef56d3407dcefdd 490 PRINTS PR00171 Sugar transporter signature 385 397 1.0E-15 T 31-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 DFR85_15095 b0cf7a6a3c2774d96ef56d3407dcefdd 490 PRINTS PR00171 Sugar transporter signature 269 279 1.0E-15 T 31-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 DFR85_15095 b0cf7a6a3c2774d96ef56d3407dcefdd 490 PRINTS PR00171 Sugar transporter signature 115 134 1.0E-15 T 31-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 DFR85_15095 b0cf7a6a3c2774d96ef56d3407dcefdd 490 PRINTS PR00171 Sugar transporter signature 362 383 1.0E-15 T 31-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 DFR85_15095 b0cf7a6a3c2774d96ef56d3407dcefdd 490 PRINTS PR00171 Sugar transporter signature 34 44 1.0E-15 T 31-10-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-189200 DFR85_15095 b0cf7a6a3c2774d96ef56d3407dcefdd 490 Gene3D G3DSA:1.20.1250.20 15 230 7.4E-51 T 31-10-2018 DFR85_15095 b0cf7a6a3c2774d96ef56d3407dcefdd 490 Gene3D G3DSA:1.20.1250.20 235 468 2.1E-43 T 31-10-2018 DFR85_15095 b0cf7a6a3c2774d96ef56d3407dcefdd 490 ProSitePatterns PS00217 Sugar transport proteins signature 2. 120 145 - T 31-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DFR85_11455 42a197624405b43e85798d1b93c54d46 111 Pfam PF02656 Domain of unknown function (DUF202) 7 78 1.6E-20 T 31-10-2018 IPR003807 Domain of unknown function DUF202 DFR85_01170 90710e7d03f52d6dd1c1f734898d2e1b 91 SUPERFAMILY SSF143011 22 89 4.19E-7 T 31-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily DFR85_03785 53f3696db3a06e05aa4a51f0d0c126d5 629 SUPERFAMILY SSF56762 4 608 6.15E-85 T 31-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_03785 53f3696db3a06e05aa4a51f0d0c126d5 629 ProSitePatterns PS00507 Nickel-dependent hydrogenases large subunit signature 1. 44 69 - T 31-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 DFR85_03785 53f3696db3a06e05aa4a51f0d0c126d5 629 Gene3D G3DSA:1.10.645.10 4 608 9.7E-199 T 31-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_03785 53f3696db3a06e05aa4a51f0d0c126d5 629 Pfam PF00374 Nickel-dependent hydrogenase 171 608 1.2E-28 T 31-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 DFR85_03785 53f3696db3a06e05aa4a51f0d0c126d5 629 Pfam PF00374 Nickel-dependent hydrogenase 44 128 3.9E-17 T 31-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 DFR85_05300 3163f9d1f06ee47b5a2dfcf3b698e9bb 422 Gene3D G3DSA:3.30.70.360 177 331 2.3E-128 T 31-10-2018 DFR85_05300 3163f9d1f06ee47b5a2dfcf3b698e9bb 422 Pfam PF01546 Peptidase family M20/M25/M40 64 416 1.7E-34 T 31-10-2018 IPR002933 Peptidase M20 GO:0016787 DFR85_05300 3163f9d1f06ee47b5a2dfcf3b698e9bb 422 Pfam PF07687 Peptidase dimerisation domain 175 318 4.3E-16 T 31-10-2018 IPR011650 Peptidase M20, dimerisation domain DFR85_05300 3163f9d1f06ee47b5a2dfcf3b698e9bb 422 Gene3D G3DSA:3.40.630.10 9 407 2.3E-128 T 31-10-2018 DFR85_05300 3163f9d1f06ee47b5a2dfcf3b698e9bb 422 SUPERFAMILY SSF53187 3 419 2.62E-47 T 31-10-2018 DFR85_00595 9e09fe71d8ebcb07e6a758493754aaee 179 SUPERFAMILY SSF54791 76 173 1.22E-15 T 31-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 DFR85_00595 9e09fe71d8ebcb07e6a758493754aaee 179 Gene3D G3DSA:3.30.1370.10 8 73 3.1E-8 T 31-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 DFR85_00595 9e09fe71d8ebcb07e6a758493754aaee 179 TIGRFAM TIGR03665 arCOG04150: arCOG04150 universal archaeal KH domain protein 3 167 4.6E-55 T 31-10-2018 IPR019964 KH domain protein, archaea DFR85_00595 9e09fe71d8ebcb07e6a758493754aaee 179 Gene3D G3DSA:3.30.1370.10 74 176 7.7E-32 T 31-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 DFR85_09395 275550eaa97e37b180d3bf945f85ec05 155 Gene3D G3DSA:1.10.10.10 1 63 2.5E-17 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_09395 275550eaa97e37b180d3bf945f85ec05 155 Pfam PF13412 Winged helix-turn-helix DNA-binding 10 57 4.3E-12 T 31-10-2018 DFR85_09395 275550eaa97e37b180d3bf945f85ec05 155 Pfam PF01037 Lrp/AsnC ligand binding domain 77 146 1.4E-18 T 31-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DFR85_09395 275550eaa97e37b180d3bf945f85ec05 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 10 26 5.6E-11 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR85_09395 275550eaa97e37b180d3bf945f85ec05 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 37 56 5.6E-11 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR85_09395 275550eaa97e37b180d3bf945f85ec05 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 26 37 5.6E-11 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR85_09395 275550eaa97e37b180d3bf945f85ec05 155 SUPERFAMILY SSF46785 10 70 5.46E-15 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_09395 275550eaa97e37b180d3bf945f85ec05 155 SUPERFAMILY SSF54909 70 153 1.34E-18 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel DFR85_09395 275550eaa97e37b180d3bf945f85ec05 155 SMART SM00344 10 116 2.8E-41 T 31-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 DFR85_09395 275550eaa97e37b180d3bf945f85ec05 155 Gene3D G3DSA:3.30.70.920 64 155 2.7E-22 T 31-10-2018 DFR85_01760 4a55d93efdb104148fec80a2f474f033 1028 Pfam PF07693 KAP family P-loop domain 63 240 8.3E-4 T 31-10-2018 IPR011646 KAP family P-loop domain DFR85_01760 4a55d93efdb104148fec80a2f474f033 1028 SUPERFAMILY SSF52540 55 214 4.92E-5 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_02055 5c5621b033c9acce17a9dfa181532f81 432 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 342 368 1.3E-12 T 31-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_02055 5c5621b033c9acce17a9dfa181532f81 432 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 213 237 1.3E-12 T 31-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_02055 5c5621b033c9acce17a9dfa181532f81 432 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 115 134 1.3E-12 T 31-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_02055 5c5621b033c9acce17a9dfa181532f81 432 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 292 311 1.3E-12 T 31-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_02055 5c5621b033c9acce17a9dfa181532f81 432 Pfam PF00361 Proton-conducting membrane transporter 110 378 3.4E-40 T 31-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_06810 dd5941a951dc27a0259c88c3cfb41680 403 Gene3D G3DSA:3.30.300.280 156 396 1.8E-151 T 31-10-2018 DFR85_06810 dd5941a951dc27a0259c88c3cfb41680 403 ProDom PD011777 SYNTHETASE TRANSFERASE METHIONINE ADENOSYLTRANSFERASE S-ADENOSYLMETHIONINE NUCLEOTIDE-BINDING METABOLISM ATP-BINDING MAGNESIUM ONE-CARBON 20 397 8.0E-171 T 31-10-2018 DFR85_06810 dd5941a951dc27a0259c88c3cfb41680 403 Pfam PF01941 S-adenosylmethionine synthetase (AdoMet synthetase) 2 399 6.8E-163 T 31-10-2018 IPR027790 S-adenosylmethionine synthase KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912 DFR85_06810 dd5941a951dc27a0259c88c3cfb41680 403 Gene3D G3DSA:3.30.300.10 26 155 1.8E-151 T 31-10-2018 DFR85_06810 dd5941a951dc27a0259c88c3cfb41680 403 Gene3D G3DSA:3.30.300.340 15 285 1.8E-151 T 31-10-2018 DFR85_06330 611f47386791db01e0f5fab77d60db30 385 Gene3D G3DSA:3.90.25.10 210 369 7.1E-150 T 31-10-2018 DFR85_06330 611f47386791db01e0f5fab77d60db30 385 SUPERFAMILY SSF51735 1 364 4.84E-46 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_06330 611f47386791db01e0f5fab77d60db30 385 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 283 1.1E-18 T 31-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 DFR85_06330 611f47386791db01e0f5fab77d60db30 385 Gene3D G3DSA:3.40.50.720 2 293 7.1E-150 T 31-10-2018 DFR85_09835 3ac6ed8b6c1cc357c990d55ad0f98de9 288 Gene3D G3DSA:3.40.50.720 1 239 7.5E-67 T 31-10-2018 DFR85_09835 3ac6ed8b6c1cc357c990d55ad0f98de9 288 Pfam PF00899 ThiF family 4 230 2.1E-53 T 31-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 DFR85_09835 3ac6ed8b6c1cc357c990d55ad0f98de9 288 SUPERFAMILY SSF69572 1 251 6.41E-75 T 31-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 DFR85_11735 c038ac5a4164eebd73fb7419117294a2 286 SUPERFAMILY SSF56176 4 143 1.54E-14 T 31-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 DFR85_11735 c038ac5a4164eebd73fb7419117294a2 286 Gene3D G3DSA:3.30.465.40 16 165 2.7E-11 T 31-10-2018 DFR85_11735 c038ac5a4164eebd73fb7419117294a2 286 Pfam PF01565 FAD binding domain 2 117 1.1E-9 T 31-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 DFR85_04490 06bb4fbf2150cf461807f1ed8062eae7 386 SUPERFAMILY SSF56747 35 172 1.92E-7 T 31-10-2018 DFR85_04320 0b0282c2236b3433b1c376218e262af7 310 SUPERFAMILY SSF53448 3 260 8.23E-52 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_04320 0b0282c2236b3433b1c376218e262af7 310 Gene3D G3DSA:3.90.550.10 1 208 3.6E-52 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_04320 0b0282c2236b3433b1c376218e262af7 310 Pfam PF00535 Glycosyl transferase family 2 7 142 6.6E-27 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 DFR85_00220 715a704ff89cac758410a5af242990e2 163 SUPERFAMILY SSF49503 39 163 6.88E-20 T 31-10-2018 IPR008972 Cupredoxin DFR85_00220 715a704ff89cac758410a5af242990e2 163 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 105 156 - T 31-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_00220 715a704ff89cac758410a5af242990e2 163 Gene3D G3DSA:2.60.40.420 34 162 1.2E-15 T 31-10-2018 IPR008972 Cupredoxin DFR85_07560 7779d5c036e4ec603dc43aa74f11da3b 82 Gene3D G3DSA:3.30.70.920 2 74 3.9E-24 T 31-10-2018 DFR85_07560 7779d5c036e4ec603dc43aa74f11da3b 82 Pfam PF01037 Lrp/AsnC ligand binding domain 6 76 1.1E-16 T 31-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DFR85_07560 7779d5c036e4ec603dc43aa74f11da3b 82 SUPERFAMILY SSF54909 2 76 7.64E-18 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel DFR85_01385 19fe83c42d4c1395dfff956540372f3d 83 Gene3D G3DSA:3.30.110.60 1 83 6.0E-17 T 31-10-2018 IPR035920 YhbY-like superfamily DFR85_01385 19fe83c42d4c1395dfff956540372f3d 83 SMART SM01103 1 79 1.9E-20 T 31-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 DFR85_01385 19fe83c42d4c1395dfff956540372f3d 83 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 10 79 1.0E-20 T 31-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 DFR85_01385 19fe83c42d4c1395dfff956540372f3d 83 Pfam PF01985 CRS1 / YhbY (CRM) domain 11 79 1.4E-15 T 31-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 DFR85_01385 19fe83c42d4c1395dfff956540372f3d 83 SUPERFAMILY SSF75471 12 77 1.57E-15 T 31-10-2018 IPR035920 YhbY-like superfamily DFR85_08605 abb19a84578ce1ff3cf23a3bb98a2939 361 Pfam PF01189 16S rRNA methyltransferase RsmB/F 166 355 1.4E-25 T 31-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 DFR85_08605 abb19a84578ce1ff3cf23a3bb98a2939 361 SUPERFAMILY SSF53335 93 355 7.13E-30 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR85_08605 abb19a84578ce1ff3cf23a3bb98a2939 361 Gene3D G3DSA:3.40.50.150 72 356 3.1E-43 T 31-10-2018 DFR85_08605 abb19a84578ce1ff3cf23a3bb98a2939 361 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 148 162 2.6E-17 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase DFR85_08605 abb19a84578ce1ff3cf23a3bb98a2939 361 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 177 187 2.6E-17 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase DFR85_08605 abb19a84578ce1ff3cf23a3bb98a2939 361 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 292 308 2.6E-17 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase DFR85_08605 abb19a84578ce1ff3cf23a3bb98a2939 361 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 243 255 2.6E-17 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase DFR85_08605 abb19a84578ce1ff3cf23a3bb98a2939 361 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 340 357 2.6E-17 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase DFR85_14765 d1e1308817cac91ef94be02883823067 232 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 9 75 2.8E-22 T 31-10-2018 IPR002831 Transcription regulator TrmB, N-terminal DFR85_14765 d1e1308817cac91ef94be02883823067 232 Gene3D G3DSA:1.10.10.10 1 98 4.3E-24 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_14765 d1e1308817cac91ef94be02883823067 232 SUPERFAMILY SSF46785 3 91 8.79E-8 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_14745 c944726429e1b53098130b71b1cc5117 310 Gene3D G3DSA:3.40.1190.20 1 310 1.2E-106 T 31-10-2018 IPR029056 Ribokinase-like DFR85_14745 c944726429e1b53098130b71b1cc5117 310 Pfam PF00294 pfkB family carbohydrate kinase 4 296 3.3E-38 T 31-10-2018 IPR011611 Carbohydrate kinase PfkB DFR85_14745 c944726429e1b53098130b71b1cc5117 310 SUPERFAMILY SSF53613 2 305 5.46E-67 T 31-10-2018 IPR029056 Ribokinase-like DFR85_13665 6d12896d55af870773c7b601c0c4e242 244 Pfam PF01987 Mitochondrial biogenesis AIM24 4 206 2.2E-43 T 31-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 DFR85_13665 6d12896d55af870773c7b601c0c4e242 244 Gene3D G3DSA:3.60.160.10 2 221 3.6E-52 T 31-10-2018 IPR036983 Mitochondrial biogenesis AIM24 superfamily DFR85_13665 6d12896d55af870773c7b601c0c4e242 244 SUPERFAMILY SSF51219 2 217 2.62E-47 T 31-10-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain superfamily DFR85_07355 a9b576244f5faa14f5a4e59ee9ce8331 178 PIRSF PIRSF006373 1 176 2.0E-67 T 31-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 DFR85_07355 a9b576244f5faa14f5a4e59ee9ce8331 178 SUPERFAMILY SSF46785 4 88 2.49E-25 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_07355 a9b576244f5faa14f5a4e59ee9ce8331 178 Hamap MF_01909 Transcription factor E [tfe]. 3 165 28.537 T 31-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 DFR85_07355 a9b576244f5faa14f5a4e59ee9ce8331 178 Gene3D G3DSA:1.10.10.10 1 88 2.5E-29 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_07355 a9b576244f5faa14f5a4e59ee9ce8331 178 TIGRFAM TIGR00373 TIGR00373: transcription factor E 5 166 7.1E-49 T 31-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 DFR85_07355 a9b576244f5faa14f5a4e59ee9ce8331 178 Pfam PF02002 TFIIE alpha subunit 6 111 6.6E-27 T 31-10-2018 IPR024550 TFIIEalpha/SarR/Rpc3 HTH domain Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 DFR85_07355 a9b576244f5faa14f5a4e59ee9ce8331 178 SMART SM00531 18 157 4.9E-41 T 31-10-2018 IPR002853 Transcription initiation factor IIE subunit alpha, N-terminal GO:0006367 Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 DFR85_08685 3b4729fc5b5aa875a5798e9471cc90a2 290 SUPERFAMILY SSF50129 10 118 1.54E-9 T 31-10-2018 IPR011032 GroES-like superfamily DFR85_08685 3b4729fc5b5aa875a5798e9471cc90a2 290 Gene3D G3DSA:3.90.180.10 9 153 2.4E-8 T 31-10-2018 DFR85_00640 f08b0a82e2d06c722636d44ad4ba8d51 355 Gene3D G3DSA:3.10.20.30 272 355 4.3E-28 T 31-10-2018 IPR012675 Beta-grasp domain superfamily DFR85_00640 f08b0a82e2d06c722636d44ad4ba8d51 355 SUPERFAMILY SSF81271 276 353 7.19E-15 T 31-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 DFR85_00640 f08b0a82e2d06c722636d44ad4ba8d51 355 Pfam PF02824 TGS domain 282 353 3.9E-16 T 31-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 DFR85_08365 abea8f91549f22bd35c7960dc14a9726 206 TIGRFAM TIGR03634 arc_protsome_B: proteasome endopeptidase complex, archaeal, beta subunit 12 194 3.1E-69 T 31-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 DFR85_08365 abea8f91549f22bd35c7960dc14a9726 206 Gene3D G3DSA:3.60.20.10 1 203 2.8E-56 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR85_08365 abea8f91549f22bd35c7960dc14a9726 206 PRINTS PR00141 Proteasome component signature 20 35 4.5E-7 T 31-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 DFR85_08365 abea8f91549f22bd35c7960dc14a9726 206 PRINTS PR00141 Proteasome component signature 151 162 4.5E-7 T 31-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 DFR85_08365 abea8f91549f22bd35c7960dc14a9726 206 PRINTS PR00141 Proteasome component signature 140 151 4.5E-7 T 31-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 DFR85_08365 abea8f91549f22bd35c7960dc14a9726 206 PRINTS PR00141 Proteasome component signature 176 187 4.5E-7 T 31-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 DFR85_08365 abea8f91549f22bd35c7960dc14a9726 206 SUPERFAMILY SSF56235 8 196 5.5E-56 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR85_08365 abea8f91549f22bd35c7960dc14a9726 206 Pfam PF00227 Proteasome subunit 11 189 3.4E-48 T 31-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 DFR85_08365 abea8f91549f22bd35c7960dc14a9726 206 Hamap MF_02113_A Proteasome subunit beta [prcB]. 8 203 32.897 T 31-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 DFR85_13580 e7c32978f6daac2ccf844ec3cb54619b 317 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 30 69 1.9E-10 T 31-10-2018 IPR011964 YVTN beta-propeller repeat DFR85_13580 e7c32978f6daac2ccf844ec3cb54619b 317 Gene3D G3DSA:2.130.10.10 163 298 5.3E-10 T 31-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 DFR85_13580 e7c32978f6daac2ccf844ec3cb54619b 317 Gene3D G3DSA:2.130.10.10 14 70 7.2E-8 T 31-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 DFR85_13580 e7c32978f6daac2ccf844ec3cb54619b 317 Gene3D G3DSA:2.130.10.10 71 159 9.8E-10 T 31-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 DFR85_13580 e7c32978f6daac2ccf844ec3cb54619b 317 SUPERFAMILY SSF51004 30 246 2.88E-30 T 31-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily DFR85_06075 11db7612a76556ff8aae087fd96f7f9e 263 SUPERFAMILY SSF56784 4 261 1.68E-63 T 31-10-2018 IPR036412 HAD-like superfamily DFR85_06075 11db7612a76556ff8aae087fd96f7f9e 263 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 8 237 5.8E-42 T 31-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA DFR85_06075 11db7612a76556ff8aae087fd96f7f9e 263 Gene3D G3DSA:3.40.50.1000 9 258 1.4E-72 T 31-10-2018 IPR023214 HAD superfamily DFR85_06075 11db7612a76556ff8aae087fd96f7f9e 263 Pfam PF13242 HAD-hyrolase-like 187 260 7.4E-19 T 31-10-2018 DFR85_06075 11db7612a76556ff8aae087fd96f7f9e 263 Pfam PF13344 Haloacid dehalogenase-like hydrolase 8 108 3.8E-24 T 31-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA DFR85_06075 11db7612a76556ff8aae087fd96f7f9e 263 Gene3D G3DSA:3.40.50.1000 85 187 1.4E-72 T 31-10-2018 IPR023214 HAD superfamily DFR85_06075 11db7612a76556ff8aae087fd96f7f9e 263 PIRSF PIRSF000915 1 263 2.9E-56 T 31-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA DFR85_07230 87224fb916de03749c2c64d7dc1c6878 228 SUPERFAMILY SSF75217 2 155 7.33E-31 T 31-10-2018 IPR029028 Alpha/beta knot methyltransferases DFR85_07230 87224fb916de03749c2c64d7dc1c6878 228 Gene3D G3DSA:3.40.1280.10 1 154 3.2E-50 T 31-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal DFR85_07230 87224fb916de03749c2c64d7dc1c6878 228 Pfam PF00588 SpoU rRNA Methylase family 2 149 1.4E-31 T 31-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 DFR85_07230 87224fb916de03749c2c64d7dc1c6878 228 PIRSF PIRSF004808 1 227 2.6E-57 T 31-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 DFR85_12780 c5b14f6e18497a6e55375a833cccf7ea 136 Gene3D G3DSA:2.40.50.100 6 132 8.1E-31 T 31-10-2018 DFR85_12780 c5b14f6e18497a6e55375a833cccf7ea 136 Pfam PF01597 Glycine cleavage H-protein 14 120 1.7E-29 T 31-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate DFR85_12780 c5b14f6e18497a6e55375a833cccf7ea 136 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 9 132 29.609 T 31-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 DFR85_12780 c5b14f6e18497a6e55375a833cccf7ea 136 SUPERFAMILY SSF51230 8 115 8.71E-24 T 31-10-2018 IPR011053 Single hybrid motif DFR85_12780 c5b14f6e18497a6e55375a833cccf7ea 136 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 53 82 - T 31-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 DFR85_03865 0540bc207e4b8eda9520e6d594fe4cea 598 Gene3D G3DSA:3.40.50.300 201 345 2.4E-24 T 31-10-2018 DFR85_03865 0540bc207e4b8eda9520e6d594fe4cea 598 Pfam PF00270 DEAD/DEAH box helicase 17 161 4.5E-15 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 DFR85_03865 0540bc207e4b8eda9520e6d594fe4cea 598 Gene3D G3DSA:3.40.50.300 7 176 1.2E-23 T 31-10-2018 DFR85_03865 0540bc207e4b8eda9520e6d594fe4cea 598 SMART SM00487 7 184 2.2E-16 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain DFR85_03865 0540bc207e4b8eda9520e6d594fe4cea 598 SUPERFAMILY SSF52540 12 334 2.88E-44 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_03865 0540bc207e4b8eda9520e6d594fe4cea 598 SMART SM00490 232 323 1.8E-17 T 31-10-2018 IPR001650 Helicase, C-terminal DFR85_03865 0540bc207e4b8eda9520e6d594fe4cea 598 Pfam PF00271 Helicase conserved C-terminal domain 216 323 1.5E-14 T 31-10-2018 IPR001650 Helicase, C-terminal DFR85_12440 7c32ba650c1fd43c7bd16ad4f583a190 297 SUPERFAMILY SSF51735 84 259 2.0E-37 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_12440 7c32ba650c1fd43c7bd16ad4f583a190 297 Gene3D G3DSA:3.40.50.720 22 284 5.4E-62 T 31-10-2018 DFR85_12440 7c32ba650c1fd43c7bd16ad4f583a190 297 SUPERFAMILY SSF52283 2 98 2.76E-22 T 31-10-2018 DFR85_12440 7c32ba650c1fd43c7bd16ad4f583a190 297 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 102 258 1.3E-34 T 31-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 DFR85_12440 7c32ba650c1fd43c7bd16ad4f583a190 297 Gene3D G3DSA:3.40.50.720 83 259 5.4E-62 T 31-10-2018 DFR85_12440 7c32ba650c1fd43c7bd16ad4f583a190 297 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 16 291 6.0E-15 T 31-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 DFR85_14685 6c99894bbb8d923c20cbb56dee3a4621 262 Gene3D G3DSA:3.40.50.720 80 223 9.1E-24 T 31-10-2018 DFR85_14685 6c99894bbb8d923c20cbb56dee3a4621 262 Pfam PF13478 XdhC Rossmann domain 81 218 7.2E-23 T 31-10-2018 IPR027051 XdhC Rossmann domain DFR85_00035 1be2b3191b72afab39f0198b0f2cc119 564 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 246 300 - T 31-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_00035 1be2b3191b72afab39f0198b0f2cc119 564 PRINTS PR01165 Cytochrome c oxidase subunit I signature 436 457 3.6E-22 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_00035 1be2b3191b72afab39f0198b0f2cc119 564 PRINTS PR01165 Cytochrome c oxidase subunit I signature 198 217 3.6E-22 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_00035 1be2b3191b72afab39f0198b0f2cc119 564 PRINTS PR01165 Cytochrome c oxidase subunit I signature 314 335 3.6E-22 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_00035 1be2b3191b72afab39f0198b0f2cc119 564 PRINTS PR01165 Cytochrome c oxidase subunit I signature 351 369 3.6E-22 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_00035 1be2b3191b72afab39f0198b0f2cc119 564 PRINTS PR01165 Cytochrome c oxidase subunit I signature 70 93 3.6E-22 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_00035 1be2b3191b72afab39f0198b0f2cc119 564 PRINTS PR01165 Cytochrome c oxidase subunit I signature 169 187 3.6E-22 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_00035 1be2b3191b72afab39f0198b0f2cc119 564 PRINTS PR01165 Cytochrome c oxidase subunit I signature 290 305 3.6E-22 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_00035 1be2b3191b72afab39f0198b0f2cc119 564 PRINTS PR01165 Cytochrome c oxidase subunit I signature 379 398 3.6E-22 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_00035 1be2b3191b72afab39f0198b0f2cc119 564 PRINTS PR01165 Cytochrome c oxidase subunit I signature 244 265 3.6E-22 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_00035 1be2b3191b72afab39f0198b0f2cc119 564 SUPERFAMILY SSF81442 29 496 2.09E-81 T 31-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_00035 1be2b3191b72afab39f0198b0f2cc119 564 Gene3D G3DSA:1.20.210.10 18 540 1.6E-71 T 31-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_00035 1be2b3191b72afab39f0198b0f2cc119 564 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 33 472 4.5E-71 T 31-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 DFR85_03505 c036482da87eec93f86802f211a7a37b 234 SUPERFAMILY SSF55961 1 135 3.76E-9 T 31-10-2018 DFR85_01330 445943959bff12d0f1b43007e3626518 294 Gene3D G3DSA:3.50.50.60 5 286 1.1E-13 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_01330 445943959bff12d0f1b43007e3626518 294 Pfam PF01266 FAD dependent oxidoreductase 3 284 7.4E-16 T 31-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 DFR85_01330 445943959bff12d0f1b43007e3626518 294 Gene3D G3DSA:3.30.9.10 73 256 1.1E-13 T 31-10-2018 DFR85_01330 445943959bff12d0f1b43007e3626518 294 SUPERFAMILY SSF51905 1 285 2.25E-16 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_08650 d753ec4ea4879a2878dc603a2a35aa5d 458 Pfam PF13632 Glycosyl transferase family group 2 135 350 3.4E-21 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 DFR85_08650 d753ec4ea4879a2878dc603a2a35aa5d 458 Gene3D G3DSA:3.90.550.10 35 258 1.6E-29 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_08650 d753ec4ea4879a2878dc603a2a35aa5d 458 SUPERFAMILY SSF53448 46 323 2.81E-34 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_09110 80dea78487aff6cba836eef24c46d2ec 170 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 28 165 3.9E-50 T 31-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_09110 80dea78487aff6cba836eef24c46d2ec 170 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 74 157 7.2E-23 T 31-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_09110 80dea78487aff6cba836eef24c46d2ec 170 Gene3D G3DSA:3.40.50.12280 8 170 6.2E-55 T 31-10-2018 DFR85_09110 80dea78487aff6cba836eef24c46d2ec 170 SUPERFAMILY SSF56770 26 165 1.96E-52 T 31-10-2018 DFR85_03610 fa3aca7ab281a47c5df2527af9a01297 130 SUPERFAMILY SSF54631 9 124 2.15E-26 T 31-10-2018 DFR85_03610 fa3aca7ab281a47c5df2527af9a01297 130 SMART SM00116 75 123 0.0084 T 31-10-2018 IPR000644 CBS domain DFR85_03610 fa3aca7ab281a47c5df2527af9a01297 130 SMART SM00116 11 59 1.7E-8 T 31-10-2018 IPR000644 CBS domain DFR85_03610 fa3aca7ab281a47c5df2527af9a01297 130 Pfam PF00571 CBS domain 10 58 6.6E-11 T 31-10-2018 IPR000644 CBS domain DFR85_03610 fa3aca7ab281a47c5df2527af9a01297 130 Pfam PF00571 CBS domain 70 122 6.9E-8 T 31-10-2018 IPR000644 CBS domain DFR85_03610 fa3aca7ab281a47c5df2527af9a01297 130 Gene3D G3DSA:3.10.580.10 3 128 7.7E-26 T 31-10-2018 DFR85_10065 9432d0ae4dc7ef5267dcc49f7a342c33 209 Pfam PF01227 GTP cyclohydrolase I 14 199 2.7E-63 T 31-10-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 DFR85_10065 9432d0ae4dc7ef5267dcc49f7a342c33 209 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 126 136 - T 31-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 DFR85_10065 9432d0ae4dc7ef5267dcc49f7a342c33 209 SUPERFAMILY SSF55620 3 200 2.15E-61 T 31-10-2018 DFR85_10065 9432d0ae4dc7ef5267dcc49f7a342c33 209 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 10 200 35.296 T 31-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 DFR85_10065 9432d0ae4dc7ef5267dcc49f7a342c33 209 Gene3D G3DSA:1.10.286.10 2 56 2.0E-14 T 31-10-2018 DFR85_10065 9432d0ae4dc7ef5267dcc49f7a342c33 209 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 76 92 - T 31-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 DFR85_10065 9432d0ae4dc7ef5267dcc49f7a342c33 209 Gene3D G3DSA:3.30.1130.10 67 202 5.1E-45 T 31-10-2018 DFR85_04640 5daf26d4e5431f49a529307ce9546bb3 353 Pfam PF02371 Transposase IS116/IS110/IS902 family 232 317 1.3E-23 T 31-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 DFR85_10480 5af1c039ede204c31d844f6fcb9eb044 256 Gene3D G3DSA:1.10.10.10 201 256 4.4E-21 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_02015 6277bdba77b3fcd9e517ccb8c31c4229 194 Gene3D G3DSA:3.40.50.150 7 178 1.1E-25 T 31-10-2018 DFR85_02015 6277bdba77b3fcd9e517ccb8c31c4229 194 SUPERFAMILY SSF53335 32 173 6.15E-23 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR85_02015 6277bdba77b3fcd9e517ccb8c31c4229 194 Pfam PF08241 Methyltransferase domain 32 118 2.4E-15 T 31-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 DFR85_09335 e3f3950900edbd450771ba690a70e13f 336 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 12 56 8.3E-11 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR85_09335 e3f3950900edbd450771ba690a70e13f 336 Gene3D G3DSA:1.20.58.220 126 239 1.9E-19 T 31-10-2018 IPR038078 PhoU-like domain superfamily DFR85_09335 e3f3950900edbd450771ba690a70e13f 336 SUPERFAMILY SSF109755 130 325 2.62E-35 T 31-10-2018 DFR85_09335 e3f3950900edbd450771ba690a70e13f 336 Gene3D G3DSA:1.20.58.220 240 330 4.6E-11 T 31-10-2018 IPR038078 PhoU-like domain superfamily DFR85_09335 e3f3950900edbd450771ba690a70e13f 336 Pfam PF01895 PhoU domain 142 231 1.2E-16 T 31-10-2018 IPR026022 PhoU domain DFR85_09335 e3f3950900edbd450771ba690a70e13f 336 Pfam PF01895 PhoU domain 244 322 1.2E-10 T 31-10-2018 IPR026022 PhoU domain DFR85_09335 e3f3950900edbd450771ba690a70e13f 336 SMART SM00966 11 57 3.7E-8 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR85_12950 237451e5931297449497da1696aa236e 429 Pfam PF00083 Sugar (and other) transporter 22 423 6.3E-43 T 31-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 DFR85_12950 237451e5931297449497da1696aa236e 429 SUPERFAMILY SSF103473 7 423 3.79E-56 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_12950 237451e5931297449497da1696aa236e 429 Gene3D G3DSA:1.20.1250.20 17 428 1.0E-79 T 31-10-2018 DFR85_12950 237451e5931297449497da1696aa236e 429 ProSitePatterns PS00216 Sugar transport proteins signature 1. 292 308 - T 31-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DFR85_07950 d8e9bf6ca6c5d9b70f8e5f862ee17113 66 Gene3D G3DSA:2.20.28.90 2 66 2.2E-22 T 31-10-2018 IPR038589 Archaeal transcription elongation factor Spt4 superfamily DFR85_07950 d8e9bf6ca6c5d9b70f8e5f862ee17113 66 SUPERFAMILY SSF63393 7 65 1.15E-17 T 31-10-2018 IPR029040 RNA polymerase subunit RPABC4/transcription elongation factor Spt4 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 DFR85_07950 d8e9bf6ca6c5d9b70f8e5f862ee17113 66 Hamap MF_00949 Transcription elongation factor Spt4 [spt4]. 9 66 26.488 T 31-10-2018 IPR007178 Archaeal transcription elongation factor Spt4 GO:0006355 DFR85_07950 d8e9bf6ca6c5d9b70f8e5f862ee17113 66 Pfam PF06093 Spt4/RpoE2 zinc finger 7 65 4.8E-14 T 31-10-2018 IPR022800 Spt4/RpoE2 zinc finger Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 DFR85_07950 d8e9bf6ca6c5d9b70f8e5f862ee17113 66 ProDom PD019197 RNA DNA-DIRECTED POLYMERASE SUBUNIT E'' POLYMERASE RPOE2 TRANSFERASE NUCLEOTIDYLTRANSFERASE E 18 63 5.0E-10 T 31-10-2018 IPR007178 Archaeal transcription elongation factor Spt4 GO:0006355 DFR85_07950 d8e9bf6ca6c5d9b70f8e5f862ee17113 66 SMART SM01389 7 66 1.9E-23 T 31-10-2018 IPR022800 Spt4/RpoE2 zinc finger Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 DFR85_07440 d577c7a9f903c69a78818ca8791fe63c 81 Gene3D G3DSA:3.10.20.30 1 81 1.9E-15 T 31-10-2018 IPR012675 Beta-grasp domain superfamily DFR85_07440 d577c7a9f903c69a78818ca8791fe63c 81 SUPERFAMILY SSF54285 2 81 2.27E-6 T 31-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp DFR85_07440 d577c7a9f903c69a78818ca8791fe63c 81 Pfam PF09138 Urm1 (Ubiquitin related modifier) 37 81 9.7E-5 T 31-10-2018 IPR015221 Ubiquitin-related modifier 1 GO:0005737|GO:0034227 Reactome: R-HSA-6782315 DFR85_00095 a28a7b5dd77b66e3673c1a20d94fba44 101 Pfam PF13601 Winged helix DNA-binding domain 22 99 4.8E-13 T 31-10-2018 IPR027395 Winged helix DNA-binding domain DFR85_00095 a28a7b5dd77b66e3673c1a20d94fba44 101 Gene3D G3DSA:1.10.10.10 5 101 1.4E-22 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_00095 a28a7b5dd77b66e3673c1a20d94fba44 101 SUPERFAMILY SSF46785 14 99 4.29E-17 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_00095 a28a7b5dd77b66e3673c1a20d94fba44 101 SMART SM00418 10 94 0.0016 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DFR85_11160 047904d849fd699054f5c4728ac21ee9 65 Pfam PF01667 Ribosomal protein S27 11 61 5.7E-22 T 31-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_11160 047904d849fd699054f5c4728ac21ee9 65 Gene3D G3DSA:2.20.25.100 12 65 4.5E-23 T 31-10-2018 IPR023407 Ribosomal protein S27e, zinc-binding domain superfamily DFR85_11160 047904d849fd699054f5c4728ac21ee9 65 SUPERFAMILY SSF57829 11 62 1.52E-19 T 31-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 DFR85_11160 047904d849fd699054f5c4728ac21ee9 65 Hamap MF_00371 30S ribosomal protein S27e [rps27e]. 5 64 21.545 T 31-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_11160 047904d849fd699054f5c4728ac21ee9 65 ProSitePatterns PS01168 Ribosomal protein S27e signature. 19 51 - T 31-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_02950 6c34a015710286e6e5d57ef57097adc1 165 SUPERFAMILY SSF51294 49 136 3.4E-7 T 31-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 DFR85_15210 87e9140578b040a55b88b15605c52e05 348 PIRSF PIRSF000112 1 346 2.6E-49 T 31-10-2018 IPR016205 Glycerol dehydrogenase GO:0016614|GO:0046872|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 DFR85_15210 87e9140578b040a55b88b15605c52e05 348 SUPERFAMILY SSF56796 5 331 1.83E-51 T 31-10-2018 DFR85_15210 87e9140578b040a55b88b15605c52e05 348 Gene3D G3DSA:1.20.1090.10 159 348 7.9E-47 T 31-10-2018 DFR85_15210 87e9140578b040a55b88b15605c52e05 348 Pfam PF13685 Iron-containing alcohol dehydrogenase 15 270 3.3E-49 T 31-10-2018 IPR032837 Glycerol-1-phosphate dehydrogenase KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 DFR85_15210 87e9140578b040a55b88b15605c52e05 348 Gene3D G3DSA:3.40.50.1970 2 158 3.4E-31 T 31-10-2018 DFR85_02205 61c2f6d28cde52b08e7c3bebd7c41a3e 435 Gene3D G3DSA:3.90.550.10 28 252 9.3E-23 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_02205 61c2f6d28cde52b08e7c3bebd7c41a3e 435 Pfam PF00535 Glycosyl transferase family 2 47 201 2.9E-18 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 DFR85_02205 61c2f6d28cde52b08e7c3bebd7c41a3e 435 SUPERFAMILY SSF53448 43 326 9.38E-33 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_10580 30f4f486cf546f8a5e9cbdb358ae49d6 244 SUPERFAMILY SSF51366 3 241 1.98E-51 T 31-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 DFR85_10580 30f4f486cf546f8a5e9cbdb358ae49d6 244 Gene3D G3DSA:3.20.20.70 1 241 9.5E-48 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_10580 30f4f486cf546f8a5e9cbdb358ae49d6 244 Pfam PF00290 Tryptophan synthase alpha chain 3 229 4.7E-36 T 31-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 DFR85_10580 30f4f486cf546f8a5e9cbdb358ae49d6 244 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 3 225 8.5E-35 T 31-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 DFR85_04880 e81c17856fc408c6c3a38ed9b4868530 179 TIGRFAM TIGR01881 cas_Cmr5: CRISPR type III-B/RAMP module-associated protein Cmr5 3 153 4.1E-7 T 31-10-2018 IPR010160 CRISPR-associated protein, Cmr5 DFR85_04880 e81c17856fc408c6c3a38ed9b4868530 179 SUPERFAMILY SSF158568 7 173 7.98E-9 T 31-10-2018 IPR023101 AF1862-like domain superfamily DFR85_15420 ae94cbf3426909d57f9834eefefda9e5 263 SUPERFAMILY SSF160104 17 246 2.75E-36 T 31-10-2018 IPR023375 Acetoacetate decarboxylase domain superfamily KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 DFR85_15420 ae94cbf3426909d57f9834eefefda9e5 263 Gene3D G3DSA:2.40.400.10 4 261 1.5E-62 T 31-10-2018 IPR023375 Acetoacetate decarboxylase domain superfamily KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 DFR85_15420 ae94cbf3426909d57f9834eefefda9e5 263 Pfam PF06314 Acetoacetate decarboxylase (ADC) 8 257 4.7E-46 T 31-10-2018 IPR010451 Acetoacetate decarboxylase GO:0016829 KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 DFR85_07190 34052482295428fdcf3210f1cc044a24 241 SUPERFAMILY SSF56235 8 239 1.1E-73 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR85_07190 34052482295428fdcf3210f1cc044a24 241 SMART SM00948 10 32 2.6E-9 T 31-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 DFR85_07190 34052482295428fdcf3210f1cc044a24 241 Gene3D G3DSA:3.60.20.10 5 240 5.0E-79 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR85_07190 34052482295428fdcf3210f1cc044a24 241 Pfam PF00227 Proteasome subunit 33 216 2.5E-58 T 31-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 DFR85_07190 34052482295428fdcf3210f1cc044a24 241 Hamap MF_00289_A Proteasome subunit alpha [prcA]. 5 237 42.455 T 31-10-2018 IPR019982 Proteasome alpha subunit, archaeal GO:0004298|GO:0005839|GO:0051603 DFR85_07190 34052482295428fdcf3210f1cc044a24 241 ProSitePatterns PS00388 Proteasome alpha-type subunits signature. 10 32 - T 31-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 DFR85_07190 34052482295428fdcf3210f1cc044a24 241 Pfam PF10584 Proteasome subunit A N-terminal signature 10 32 1.5E-12 T 31-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 DFR85_07190 34052482295428fdcf3210f1cc044a24 241 TIGRFAM TIGR03633 arc_protsome_A: proteasome endopeptidase complex, archaeal, alpha subunit 8 237 9.6E-98 T 31-10-2018 IPR019982 Proteasome alpha subunit, archaeal GO:0004298|GO:0005839|GO:0051603 DFR85_13530 118dc7ae789258cb89a76f9279f57559 262 Pfam PF03787 RAMP superfamily 15 235 1.8E-15 T 31-10-2018 IPR005537 CRISPR type III-associated RAMP protein DFR85_02465 f9782111b7f8a5064f094e4ffbfbc189 212 Pfam PF02223 Thymidylate kinase 8 198 3.1E-25 T 31-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 DFR85_02465 f9782111b7f8a5064f094e4ffbfbc189 212 Gene3D G3DSA:3.40.50.300 1 210 3.3E-62 T 31-10-2018 DFR85_02465 f9782111b7f8a5064f094e4ffbfbc189 212 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 2 198 2.2E-29 T 31-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 DFR85_02465 f9782111b7f8a5064f094e4ffbfbc189 212 SUPERFAMILY SSF52540 1 209 7.39E-34 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_02465 f9782111b7f8a5064f094e4ffbfbc189 212 Hamap MF_00165 Thymidylate kinase [tmk]. 4 208 17.216 T 31-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 DFR85_14510 a49877266a43125785a43d4fed3233f4 351 SUPERFAMILY SSF103473 6 346 5.36E-10 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_08885 da81a679db81cf69c60019143bdba297 132 Gene3D G3DSA:3.30.420.80 1 132 3.9E-57 T 31-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 DFR85_08885 da81a679db81cf69c60019143bdba297 132 TIGRFAM TIGR03628 arch_S11P: ribosomal protein uS11 8 124 3.2E-61 T 31-10-2018 IPR019961 Ribosomal protein S11, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_08885 da81a679db81cf69c60019143bdba297 132 ProSitePatterns PS00054 Ribosomal protein S11 signature. 97 119 - T 31-10-2018 IPR018102 Ribosomal S11, conserved site DFR85_08885 da81a679db81cf69c60019143bdba297 132 PIRSF PIRSF002131 1 131 6.1E-32 T 31-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 DFR85_08885 da81a679db81cf69c60019143bdba297 132 Pfam PF00411 Ribosomal protein S11 10 128 1.6E-47 T 31-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 DFR85_08885 da81a679db81cf69c60019143bdba297 132 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 4 129 22.236 T 31-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 DFR85_08885 da81a679db81cf69c60019143bdba297 132 SUPERFAMILY SSF53137 5 130 1.7E-34 T 31-10-2018 DFR85_03960 f7bf2dd61e9550c2c6ad3b54708d25a0 135 Gene3D G3DSA:3.20.20.70 1 134 5.3E-13 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_03960 f7bf2dd61e9550c2c6ad3b54708d25a0 135 SUPERFAMILY SSF102114 2 96 2.94E-9 T 31-10-2018 DFR85_00730 e0a21f223b6509492d558f8a2cb5a601 76 Pfam PF01037 Lrp/AsnC ligand binding domain 18 76 7.7E-11 T 31-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain DFR85_00730 e0a21f223b6509492d558f8a2cb5a601 76 SUPERFAMILY SSF54909 6 76 3.89E-11 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel DFR85_00730 e0a21f223b6509492d558f8a2cb5a601 76 Gene3D G3DSA:3.30.70.920 4 74 1.1E-18 T 31-10-2018 DFR85_06430 57699de2291f6330206cb82674e43e19 462 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 461 94.235 T 31-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 DFR85_06430 57699de2291f6330206cb82674e43e19 462 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 235 412 2.0E-35 T 31-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 DFR85_06430 57699de2291f6330206cb82674e43e19 462 Gene3D G3DSA:3.40.50.300 2 227 7.3E-25 T 31-10-2018 DFR85_06430 57699de2291f6330206cb82674e43e19 462 SUPERFAMILY SSF52540 3 223 3.01E-24 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_06430 57699de2291f6330206cb82674e43e19 462 SUPERFAMILY SSF52317 177 373 1.74E-26 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like DFR85_06430 57699de2291f6330206cb82674e43e19 462 Gene3D G3DSA:3.40.50.880 233 448 1.8E-17 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like DFR85_06430 57699de2291f6330206cb82674e43e19 462 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 221 1.8E-9 T 31-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain DFR85_15570 b1f3c9b1a794abbc09474881958a20bf 398 SUPERFAMILY SSF51004 116 386 2.04E-31 T 31-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily DFR85_15570 b1f3c9b1a794abbc09474881958a20bf 398 Gene3D G3DSA:2.130.10.10 113 388 1.8E-22 T 31-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 DFR85_01300 2b8425df11f7dadfc07b76da685121c9 582 Gene3D G3DSA:3.40.50.300 388 577 2.6E-14 T 31-10-2018 DFR85_01300 2b8425df11f7dadfc07b76da685121c9 582 Gene3D G3DSA:3.40.50.300 2 301 2.4E-11 T 31-10-2018 DFR85_01300 2b8425df11f7dadfc07b76da685121c9 582 SUPERFAMILY SSF52540 5 263 1.46E-7 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_01300 2b8425df11f7dadfc07b76da685121c9 582 SUPERFAMILY SSF52540 306 571 5.31E-8 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_08165 6bf0aa0225a7a08f5951b43479e9aa20 184 Hamap MF_00039 Putative adenylate kinase. 1 164 22.591 T 31-10-2018 IPR020618 Adenylate kinase isoenzyme 6 GO:0004017|GO:0005524 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 DFR85_08165 6bf0aa0225a7a08f5951b43479e9aa20 184 SUPERFAMILY SSF52540 1 153 3.92E-18 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_08165 6bf0aa0225a7a08f5951b43479e9aa20 184 Pfam PF13238 AAA domain 3 120 9.6E-18 T 31-10-2018 DFR85_08165 6bf0aa0225a7a08f5951b43479e9aa20 184 Gene3D G3DSA:3.40.50.300 1 166 3.7E-37 T 31-10-2018 DFR85_03360 760ef30eb8ef8eee75ad4eca81a73c60 457 Pfam PF01523 Putative modulator of DNA gyrase 15 307 1.8E-41 T 31-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 DFR85_03360 760ef30eb8ef8eee75ad4eca81a73c60 457 PIRSF PIRSF004919 1 457 1.2E-133 T 31-10-2018 IPR025502 TldD DFR85_03360 760ef30eb8ef8eee75ad4eca81a73c60 457 SUPERFAMILY SSF111283 12 454 1.28E-78 T 31-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 DFR85_13650 5b92757ff09548f30336f49da246fa88 274 Gene3D G3DSA:1.20.1250.20 1 254 9.8E-33 T 31-10-2018 DFR85_13650 5b92757ff09548f30336f49da246fa88 274 ProSitePatterns PS00216 Sugar transport proteins signature 1. 114 130 - T 31-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DFR85_13650 5b92757ff09548f30336f49da246fa88 274 Pfam PF00083 Sugar (and other) transporter 1 250 2.5E-19 T 31-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 DFR85_13650 5b92757ff09548f30336f49da246fa88 274 SUPERFAMILY SSF103473 1 249 2.35E-22 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_15390 656a06951982a0869bf715a398fcd9b1 386 Gene3D G3DSA:3.40.47.10 2 385 4.6E-118 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR85_15390 656a06951982a0869bf715a398fcd9b1 386 SUPERFAMILY SSF53901 5 229 1.23E-44 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR85_15390 656a06951982a0869bf715a398fcd9b1 386 Pfam PF02803 Thiolase, C-terminal domain 241 357 3.8E-9 T 31-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 DFR85_15390 656a06951982a0869bf715a398fcd9b1 386 SUPERFAMILY SSF53901 231 385 1.28E-26 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 DFR85_15390 656a06951982a0869bf715a398fcd9b1 386 Pfam PF00108 Thiolase, N-terminal domain 5 223 3.4E-21 T 31-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 DFR85_15390 656a06951982a0869bf715a398fcd9b1 386 PIRSF PIRSF000429 1 386 8.1E-62 T 31-10-2018 IPR002155 Thiolase GO:0016747 DFR85_08055 980a8d156952c770e3326dc19de864fa 204 SUPERFAMILY SSF52507 18 203 7.98E-50 T 31-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 DFR85_08055 980a8d156952c770e3326dc19de864fa 204 Pfam PF02441 Flavoprotein 18 183 8.8E-28 T 31-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 DFR85_08055 980a8d156952c770e3326dc19de864fa 204 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 20 202 6.7E-59 T 31-10-2018 IPR004507 Flavin prenyltransferase UbiX-like DFR85_08055 980a8d156952c770e3326dc19de864fa 204 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 18 204 32.829 T 31-10-2018 IPR004507 Flavin prenyltransferase UbiX-like DFR85_08055 980a8d156952c770e3326dc19de864fa 204 Gene3D G3DSA:3.40.50.1950 10 204 2.1E-65 T 31-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 DFR85_14750 ec7151252d526cb3a7a0e61b10c442b2 507 Gene3D G3DSA:3.40.309.10 271 470 1.2E-124 T 31-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 DFR85_14750 ec7151252d526cb3a7a0e61b10c442b2 507 Gene3D G3DSA:3.40.605.10 42 270 1.2E-124 T 31-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 DFR85_14750 ec7151252d526cb3a7a0e61b10c442b2 507 Pfam PF00171 Aldehyde dehydrogenase family 40 493 2.1E-109 T 31-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 DFR85_14750 ec7151252d526cb3a7a0e61b10c442b2 507 SUPERFAMILY SSF53720 22 499 9.95E-120 T 31-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 DFR85_04070 ba8ab945e9fcbcbb024ca200434fbd73 161 SUPERFAMILY SSF158372 17 65 2.49E-5 T 31-10-2018 IPR036809 AF1782-like superfamily DFR85_04070 ba8ab945e9fcbcbb024ca200434fbd73 161 Gene3D G3DSA:1.20.120.330 43 161 4.5E-37 T 31-10-2018 DFR85_04070 ba8ab945e9fcbcbb024ca200434fbd73 161 Pfam PF05942 Archaeal PaREP1/PaREP8 family 42 153 6.5E-36 T 31-10-2018 IPR010268 Archaeal PaREP1 DFR85_00080 76c73c240bf449360e6209c38309b75a 66 Pfam PF11755 Protein of unknown function (DUF3311) 23 61 7.9E-9 T 31-10-2018 IPR021741 Protein of unknown function DUF3311 DFR85_08800 cb82add8b9710f5c1bc20e232a7d65ed 103 SUPERFAMILY SSF143011 30 98 4.58E-10 T 31-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily DFR85_08800 cb82add8b9710f5c1bc20e232a7d65ed 103 Gene3D G3DSA:3.30.2310.20 5 101 8.8E-8 T 31-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily DFR85_08800 cb82add8b9710f5c1bc20e232a7d65ed 103 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 8 99 7.3E-6 T 31-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family DFR85_14110 28a6492f58885328b027828d877dea46 510 ProSitePatterns PS00507 Nickel-dependent hydrogenases large subunit signature 1. 38 63 - T 31-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 DFR85_14110 28a6492f58885328b027828d877dea46 510 SUPERFAMILY SSF56762 5 497 3.27E-100 T 31-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_14110 28a6492f58885328b027828d877dea46 510 Gene3D G3DSA:1.10.645.10 2 509 1.5E-119 T 31-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_14110 28a6492f58885328b027828d877dea46 510 Pfam PF00374 Nickel-dependent hydrogenase 140 497 1.3E-50 T 31-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 DFR85_14110 28a6492f58885328b027828d877dea46 510 Pfam PF00374 Nickel-dependent hydrogenase 38 117 2.1E-19 T 31-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 DFR85_07530 8206509f079284bed944fc7eef35fc8d 106 SUPERFAMILY SSF57783 1 79 3.91E-19 T 31-10-2018 DFR85_07530 8206509f079284bed944fc7eef35fc8d 106 Pfam PF05129 Transcription elongation factor Elf1 like 3 73 2.0E-18 T 31-10-2018 IPR007808 Transcription elongation factor 1 DFR85_06565 53e510ea681426503af7851df98669bb 56 Gene3D G3DSA:2.20.28.160 1 56 1.5E-26 T 31-10-2018 DFR85_03405 56dbdca69c74248e0a750aad234d9c7a 68 SUPERFAMILY SSF89447 28 53 2.62E-6 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily DFR85_03405 56dbdca69c74248e0a750aad234d9c7a 68 Gene3D G3DSA:2.10.260.10 23 62 1.8E-5 T 31-10-2018 DFR85_12395 c46a45217601fb441dc24224f43caf37 380 Gene3D G3DSA:1.10.8.60 233 315 1.8E-13 T 31-10-2018 DFR85_12395 c46a45217601fb441dc24224f43caf37 380 Gene3D G3DSA:3.40.50.300 9 232 4.7E-37 T 31-10-2018 DFR85_12395 c46a45217601fb441dc24224f43caf37 380 SUPERFAMILY SSF52540 10 289 8.58E-34 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_12395 c46a45217601fb441dc24224f43caf37 380 Pfam PF01637 ATPase domain predominantly from Archaea 13 274 9.5E-15 T 31-10-2018 IPR011579 ATPase domain GO:0005524 DFR85_12115 744b4927e8ed68f7347ed8efabce2991 123 TIGRFAM TIGR01878 cas_Csa5: CRISPR type I-A/APERN-associated protein Csa5 18 115 7.3E-25 T 31-10-2018 IPR010157 CRISPR type I-A/APERN-associated protein Csa5 DFR85_12115 744b4927e8ed68f7347ed8efabce2991 123 Pfam PF09702 CRISPR-associated protein (Cas_Csa5) 18 115 1.5E-34 T 31-10-2018 IPR010157 CRISPR type I-A/APERN-associated protein Csa5 DFR85_00710 56693ffe1f4debed9e816705c5c26d2c 262 Gene3D G3DSA:3.20.20.60 1 262 7.2E-95 T 31-10-2018 DFR85_00710 56693ffe1f4debed9e816705c5c26d2c 262 SUPERFAMILY SSF51621 3 256 2.69E-89 T 31-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 DFR85_00710 56693ffe1f4debed9e816705c5c26d2c 262 PIRSF PIRSF000388 1 260 2.7E-94 T 31-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 DFR85_00710 56693ffe1f4debed9e816705c5c26d2c 262 Pfam PF02548 Ketopantoate hydroxymethyltransferase 3 253 1.5E-96 T 31-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 DFR85_00710 56693ffe1f4debed9e816705c5c26d2c 262 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 1 255 2.2E-87 T 31-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 DFR85_00710 56693ffe1f4debed9e816705c5c26d2c 262 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 4 258 37.308 T 31-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 DFR85_13940 fe5dac5060490363a9fed889c3680110 471 Pfam PF12679 ABC-2 family transporter protein 201 468 2.3E-16 T 31-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 DFR85_13940 fe5dac5060490363a9fed889c3680110 471 SUPERFAMILY SSF49464 65 115 6.15E-5 T 31-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily DFR85_02125 f1f091552edcebf5e4237914ad731c8a 135 SUPERFAMILY SSF46785 2 87 1.53E-23 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_02125 f1f091552edcebf5e4237914ad731c8a 135 Gene3D G3DSA:1.10.10.10 1 105 1.2E-22 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_02125 f1f091552edcebf5e4237914ad731c8a 135 Pfam PF03551 Transcriptional regulator PadR-like family 15 83 3.4E-16 T 31-10-2018 IPR005149 Transcription regulator PadR, N-terminal DFR85_10820 fbe5f005e7bdd16ab179ec301366f480 223 Pfam PF01467 Cytidylyltransferase-like 85 213 9.2E-16 T 31-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 DFR85_10820 fbe5f005e7bdd16ab179ec301366f480 223 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 83 144 2.2E-16 T 31-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 DFR85_10820 fbe5f005e7bdd16ab179ec301366f480 223 SUPERFAMILY SSF158372 4 75 1.18E-17 T 31-10-2018 IPR036809 AF1782-like superfamily DFR85_10820 fbe5f005e7bdd16ab179ec301366f480 223 Pfam PF04010 Protein of unknown function (DUF357) 10 68 1.3E-14 T 31-10-2018 IPR023140 Domain of unknown function DUF357 DFR85_10820 fbe5f005e7bdd16ab179ec301366f480 223 Gene3D G3DSA:1.20.1270.90 2 77 4.7E-20 T 31-10-2018 DFR85_10820 fbe5f005e7bdd16ab179ec301366f480 223 Gene3D G3DSA:3.40.50.620 80 199 1.4E-32 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR85_10820 fbe5f005e7bdd16ab179ec301366f480 223 SUPERFAMILY SSF52374 81 213 2.03E-19 T 31-10-2018 DFR85_09440 4962a22f3ca5cf30c918ff640c2bc95b 251 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 250 2.0E-105 T 31-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 DFR85_09440 4962a22f3ca5cf30c918ff640c2bc95b 251 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 250 45.107 T 31-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 DFR85_09440 4962a22f3ca5cf30c918ff640c2bc95b 251 Gene3D G3DSA:3.20.20.70 1 251 7.4E-107 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_09440 4962a22f3ca5cf30c918ff640c2bc95b 251 SUPERFAMILY SSF51366 1 250 4.32E-78 T 31-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 DFR85_09440 4962a22f3ca5cf30c918ff640c2bc95b 251 Pfam PF00977 Histidine biosynthesis protein 5 233 4.1E-82 T 31-10-2018 IPR006062 Histidine biosynthesis GO:0000105 DFR85_15225 ca88f778d2e722993080fb1c4bcf7194 785 TIGRFAM TIGR02416 CO_dehy_Mo_lg: carbon-monoxide dehydrogenase, large subunit 21 774 0.0 T 31-10-2018 IPR012780 Carbon-monoxide dehydrogenase, large subunit GO:0005507|GO:0018492|GO:0030151 MetaCyc: PWY-7750 DFR85_15225 ca88f778d2e722993080fb1c4bcf7194 785 SUPERFAMILY SSF54665 9 157 1.31E-44 T 31-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily DFR85_15225 ca88f778d2e722993080fb1c4bcf7194 785 Gene3D G3DSA:3.30.365.10 193 289 6.7E-73 T 31-10-2018 DFR85_15225 ca88f778d2e722993080fb1c4bcf7194 785 SMART SM01008 27 136 8.1E-46 T 31-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DFR85_15225 ca88f778d2e722993080fb1c4bcf7194 785 Gene3D G3DSA:3.30.365.10 464 629 1.6E-148 T 31-10-2018 DFR85_15225 ca88f778d2e722993080fb1c4bcf7194 785 Gene3D G3DSA:3.30.365.10 377 754 1.6E-148 T 31-10-2018 DFR85_15225 ca88f778d2e722993080fb1c4bcf7194 785 Gene3D G3DSA:3.30.365.10 139 360 6.7E-73 T 31-10-2018 DFR85_15225 ca88f778d2e722993080fb1c4bcf7194 785 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 154 714 1.6E-173 T 31-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 DFR85_15225 ca88f778d2e722993080fb1c4bcf7194 785 Gene3D G3DSA:3.90.1170.50 3 135 2.9E-46 T 31-10-2018 DFR85_15225 ca88f778d2e722993080fb1c4bcf7194 785 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 27 135 1.8E-33 T 31-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead DFR85_15225 ca88f778d2e722993080fb1c4bcf7194 785 SUPERFAMILY SSF56003 128 778 5.89E-200 T 31-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 DFR85_12040 7e35e88c2ff9fe635f97d9a56b8a964c 179 Gene3D G3DSA:2.60.120.10 3 178 3.9E-65 T 31-10-2018 IPR014710 RmlC-like jelly roll fold DFR85_12040 7e35e88c2ff9fe635f97d9a56b8a964c 179 SUPERFAMILY SSF51182 3 177 1.09E-64 T 31-10-2018 IPR011051 RmlC-like cupin domain superfamily DFR85_12040 7e35e88c2ff9fe635f97d9a56b8a964c 179 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 7 171 4.4E-59 T 31-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 DFR85_12040 7e35e88c2ff9fe635f97d9a56b8a964c 179 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 4 173 2.6E-62 T 31-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 DFR85_12040 7e35e88c2ff9fe635f97d9a56b8a964c 179 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 3 171 2.0E-59 T 31-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 DFR85_01095 197bf596af97129b9bc71f4112983f73 360 Gene3D G3DSA:3.50.50.60 206 343 7.0E-12 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_01095 197bf596af97129b9bc71f4112983f73 360 SUPERFAMILY SSF51971 2 347 3.41E-21 T 31-10-2018 DFR85_01095 197bf596af97129b9bc71f4112983f73 360 Pfam PF01266 FAD dependent oxidoreductase 2 342 3.1E-40 T 31-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 DFR85_01095 197bf596af97129b9bc71f4112983f73 360 Gene3D G3DSA:3.50.50.60 1 75 3.0E-12 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_01095 197bf596af97129b9bc71f4112983f73 360 Gene3D G3DSA:3.30.9.10 225 305 7.0E-12 T 31-10-2018 DFR85_07610 900136a2d2192904a7d62a0d835017cb 172 Pfam PF03657 Uncharacterised protein family (UPF0113) 31 170 4.7E-5 T 31-10-2018 IPR005155 Ribosome biogenesis factor NIP7-like Reactome: R-HSA-6791226 DFR85_07610 900136a2d2192904a7d62a0d835017cb 172 Gene3D G3DSA:2.30.130.10 104 170 8.9E-6 T 31-10-2018 IPR036974 PUA domain superfamily GO:0003723 DFR85_07770 9579b860b89a8f3d90597ec5eaf5435f 151 Pfam PF02577 Bifunctional nuclease 77 144 2.6E-9 T 31-10-2018 IPR003729 Bifunctional nuclease domain GO:0004518 DFR85_07770 9579b860b89a8f3d90597ec5eaf5435f 151 SUPERFAMILY SSF103256 7 147 1.22E-26 T 31-10-2018 IPR036104 Bifunctional nuclease superfamily GO:0004518 DFR85_07770 9579b860b89a8f3d90597ec5eaf5435f 151 Gene3D G3DSA:3.10.690.10 65 151 1.5E-8 T 31-10-2018 IPR036104 Bifunctional nuclease superfamily GO:0004518 DFR85_05245 f181c7a5c0d167026fd8a3bf99b9ed12 279 Pfam PF02673 Bacitracin resistance protein BacA 8 259 1.2E-47 T 31-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 DFR85_05245 f181c7a5c0d167026fd8a3bf99b9ed12 279 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 2 273 14.151 T 31-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 DFR85_05785 e2f9d7aa06b577ce151eaab6192646be 255 SUPERFAMILY SSF46785 1 60 6.72E-10 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_05785 e2f9d7aa06b577ce151eaab6192646be 255 Gene3D G3DSA:1.10.10.10 1 48 2.3E-11 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_05785 e2f9d7aa06b577ce151eaab6192646be 255 Gene3D G3DSA:1.10.10.10 129 175 3.1E-5 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_05785 e2f9d7aa06b577ce151eaab6192646be 255 SMART SM00344 1 103 6.4E-4 T 31-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 DFR85_05785 e2f9d7aa06b577ce151eaab6192646be 255 SUPERFAMILY SSF46785 130 175 4.55E-5 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_05785 e2f9d7aa06b577ce151eaab6192646be 255 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 5.2E-7 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR85_05785 e2f9d7aa06b577ce151eaab6192646be 255 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 5.2E-7 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR85_05785 e2f9d7aa06b577ce151eaab6192646be 255 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 5.2E-7 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 DFR85_05785 e2f9d7aa06b577ce151eaab6192646be 255 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 48 3.6E-13 T 31-10-2018 DFR85_05785 e2f9d7aa06b577ce151eaab6192646be 255 Pfam PF13412 Winged helix-turn-helix DNA-binding 131 171 6.8E-6 T 31-10-2018 DFR85_11085 b2a842e77bb9663880282059a0e55035 146 Pfam PF00582 Universal stress protein family 1 146 9.3E-35 T 31-10-2018 IPR006016 UspA DFR85_11085 b2a842e77bb9663880282059a0e55035 146 PRINTS PR01438 Universal stress protein signature 124 146 2.0E-20 T 31-10-2018 IPR006015 Universal stress protein A DFR85_11085 b2a842e77bb9663880282059a0e55035 146 PRINTS PR01438 Universal stress protein signature 106 118 2.0E-20 T 31-10-2018 IPR006015 Universal stress protein A DFR85_11085 b2a842e77bb9663880282059a0e55035 146 PRINTS PR01438 Universal stress protein signature 2 20 2.0E-20 T 31-10-2018 IPR006015 Universal stress protein A DFR85_11085 b2a842e77bb9663880282059a0e55035 146 SUPERFAMILY SSF52402 2 146 9.07E-36 T 31-10-2018 DFR85_11085 b2a842e77bb9663880282059a0e55035 146 Gene3D G3DSA:3.40.50.620 1 146 3.6E-38 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold DFR85_05725 7d0f412a82dd7fc452efa2d194fa35c6 375 Pfam PF09376 NurA domain 64 338 2.4E-14 T 31-10-2018 IPR018977 NurA domain DFR85_05725 7d0f412a82dd7fc452efa2d194fa35c6 375 SMART SM00933 62 341 5.2E-15 T 31-10-2018 IPR018977 NurA domain DFR85_09610 7e7c7f0a7053d9758004a9cea39379df 704 Pfam PF01496 V-type ATPase 116kDa subunit family 205 370 2.4E-27 T 31-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 DFR85_13585 68bce4da908cc59d7b4ef87fa44e0a4c 279 SUPERFAMILY SSF103481 175 271 3.01E-8 T 31-10-2018 DFR85_13585 68bce4da908cc59d7b4ef87fa44e0a4c 279 Pfam PF00892 EamA-like transporter family 139 269 5.4E-15 T 31-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 DFR85_13585 68bce4da908cc59d7b4ef87fa44e0a4c 279 Pfam PF00892 EamA-like transporter family 7 131 1.2E-14 T 31-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 DFR85_13585 68bce4da908cc59d7b4ef87fa44e0a4c 279 SUPERFAMILY SSF103481 42 132 1.7E-5 T 31-10-2018 DFR85_01320 2b465a4ae1cc93f8e4061af08855ae4e 211 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 184 3.1E-38 T 31-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 DFR85_01320 2b465a4ae1cc93f8e4061af08855ae4e 211 Gene3D G3DSA:3.40.50.1240 1 195 6.2E-42 T 31-10-2018 IPR029033 Histidine phosphatase superfamily DFR85_01320 2b465a4ae1cc93f8e4061af08855ae4e 211 SUPERFAMILY SSF53254 1 191 7.9E-42 T 31-10-2018 IPR029033 Histidine phosphatase superfamily DFR85_01320 2b465a4ae1cc93f8e4061af08855ae4e 211 PIRSF PIRSF000709 3 193 1.6E-7 T 31-10-2018 DFR85_01320 2b465a4ae1cc93f8e4061af08855ae4e 211 SMART SM00855 3 150 1.6E-14 T 31-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 DFR85_09410 6b503253b2deb97ee8c612e3fc765e0b 489 SMART SM00729 203 434 3.9E-20 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 DFR85_09410 6b503253b2deb97ee8c612e3fc765e0b 489 Pfam PF04055 Radical SAM superfamily 207 393 6.7E-15 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR85_09410 6b503253b2deb97ee8c612e3fc765e0b 489 SUPERFAMILY SSF102114 170 400 8.04E-15 T 31-10-2018 DFR85_09410 6b503253b2deb97ee8c612e3fc765e0b 489 Gene3D G3DSA:3.80.30.20 203 410 2.1E-22 T 31-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe DFR85_15825 67c7a93ca6d2de0e7134d804922461ef 141 Gene3D G3DSA:3.10.580.10 1 135 8.3E-36 T 31-10-2018 DFR85_15825 67c7a93ca6d2de0e7134d804922461ef 141 Pfam PF00571 CBS domain 5 59 2.4E-11 T 31-10-2018 IPR000644 CBS domain DFR85_15825 67c7a93ca6d2de0e7134d804922461ef 141 Pfam PF00571 CBS domain 76 122 3.5E-11 T 31-10-2018 IPR000644 CBS domain DFR85_15825 67c7a93ca6d2de0e7134d804922461ef 141 SUPERFAMILY SSF54631 4 122 1.39E-31 T 31-10-2018 DFR85_15825 67c7a93ca6d2de0e7134d804922461ef 141 SMART SM00116 76 124 1.1E-10 T 31-10-2018 IPR000644 CBS domain DFR85_15825 67c7a93ca6d2de0e7134d804922461ef 141 SMART SM00116 12 59 3.3E-7 T 31-10-2018 IPR000644 CBS domain DFR85_04740 c2a69f6fd7305fd3deb810ac03207bff 113 Pfam PF04693 Archaeal putative transposase ISC1217 8 112 7.3E-34 T 31-10-2018 IPR006783 Transposase, ISC1217 DFR85_04585 32bac2e357ea12f7cf51b55d81fa24f6 81 Gene3D G3DSA:1.20.120.330 1 81 5.2E-27 T 31-10-2018 DFR85_04585 32bac2e357ea12f7cf51b55d81fa24f6 81 Pfam PF05942 Archaeal PaREP1/PaREP8 family 4 74 2.7E-17 T 31-10-2018 IPR010268 Archaeal PaREP1 DFR85_12425 438e5c5dfaf6850326a812be4091f4be 391 Gene3D G3DSA:1.10.10.10 1 71 1.7E-14 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_12425 438e5c5dfaf6850326a812be4091f4be 391 SUPERFAMILY SSF46785 2 68 1.01E-11 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_12425 438e5c5dfaf6850326a812be4091f4be 391 Pfam PF12840 Helix-turn-helix domain 2 53 7.2E-8 T 31-10-2018 DFR85_12425 438e5c5dfaf6850326a812be4091f4be 391 SMART SM00418 2 75 5.2E-4 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DFR85_00810 79e073df14e6300c830cf415064336f5 176 SUPERFAMILY SSF53271 4 166 3.28E-36 T 31-10-2018 IPR029057 Phosphoribosyltransferase-like DFR85_00810 79e073df14e6300c830cf415064336f5 176 Pfam PF00156 Phosphoribosyl transferase domain 9 151 3.2E-25 T 31-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 DFR85_00810 79e073df14e6300c830cf415064336f5 176 Gene3D G3DSA:3.40.50.2020 1 176 1.7E-52 T 31-10-2018 DFR85_12990 b9c7e30f0bcb59d4a77105ebfaf1f590 132 Pfam PF11485 Protein of unknown function (DUF3211) 3 132 5.0E-37 T 31-10-2018 IPR021578 Protein of unknown function DUF3211 DFR85_12990 b9c7e30f0bcb59d4a77105ebfaf1f590 132 Gene3D G3DSA:3.30.530.20 1 132 6.3E-35 T 31-10-2018 IPR023393 START-like domain superfamily DFR85_14335 693906ffe3c8cd5aaa78949ca89ded62 148 Gene3D G3DSA:3.30.300.130 1 93 1.5E-20 T 31-10-2018 IPR034904 Fe-S cluster assembly domain superfamily DFR85_14335 693906ffe3c8cd5aaa78949ca89ded62 148 Pfam PF01883 Iron-sulfur cluster assembly protein 1 65 6.9E-12 T 31-10-2018 IPR002744 MIP18 family-like DFR85_14335 693906ffe3c8cd5aaa78949ca89ded62 148 SUPERFAMILY SSF117916 1 91 5.89E-17 T 31-10-2018 IPR034904 Fe-S cluster assembly domain superfamily DFR85_04865 669385be768c95767b40d9444d55cf4e 934 TIGRFAM TIGR02577 cas_TM1794_Cmr2: CRISPR-associated protein Cas10/Cmr2, subtype III-B 163 802 7.2E-117 T 31-10-2018 IPR013407 CRISPR-associated protein Cmr2 DFR85_04865 669385be768c95767b40d9444d55cf4e 934 Pfam PF12469 CRISPR-associated protein 164 304 1.8E-30 T 31-10-2018 IPR024615 CRISPR-associated protein Cmr2, N-terminal DFR85_04865 669385be768c95767b40d9444d55cf4e 934 Gene3D G3DSA:3.30.70.2220 122 334 3.7E-25 T 31-10-2018 IPR038242 Cmr2, N-terminal domain superfamily DFR85_09460 07761f5c172c6366fe88a7cac87ea54c 357 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 218 227 - T 31-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 DFR85_09460 07761f5c172c6366fe88a7cac87ea54c 357 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 24 350 2.7E-87 T 31-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 DFR85_09460 07761f5c172c6366fe88a7cac87ea54c 357 Gene3D G3DSA:3.90.1150.10 27 346 2.8E-81 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 DFR85_09460 07761f5c172c6366fe88a7cac87ea54c 357 Pfam PF00155 Aminotransferase class I and II 32 343 1.7E-40 T 31-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 DFR85_09460 07761f5c172c6366fe88a7cac87ea54c 357 Gene3D G3DSA:3.40.640.10 52 268 2.8E-81 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR85_09460 07761f5c172c6366fe88a7cac87ea54c 357 SUPERFAMILY SSF53383 25 350 1.48E-67 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase DFR85_04960 0e9a418e5901e154312cd528a835f150 258 Pfam PF13489 Methyltransferase domain 41 218 8.0E-18 T 31-10-2018 DFR85_04960 0e9a418e5901e154312cd528a835f150 258 Gene3D G3DSA:3.40.50.150 19 257 2.0E-33 T 31-10-2018 DFR85_04960 0e9a418e5901e154312cd528a835f150 258 SUPERFAMILY SSF53335 9 228 9.19E-29 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR85_12125 4a3bd4a20761e2557502b301a6af4eb3 226 Pfam PF04240 Carotenoid biosynthesis protein 21 214 4.2E-28 T 31-10-2018 IPR007354 Carotene biosynthesis associated membrane protein DFR85_11920 1d1cb275786531b0f4a6f188ee30e52c 116 SUPERFAMILY SSF81301 19 98 3.6E-16 T 31-10-2018 DFR85_11920 1d1cb275786531b0f4a6f188ee30e52c 116 Pfam PF01909 Nucleotidyltransferase domain 19 74 2.3E-10 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 DFR85_11920 1d1cb275786531b0f4a6f188ee30e52c 116 Gene3D G3DSA:3.30.460.10 1 108 4.4E-22 T 31-10-2018 DFR85_12235 8cc28a02822188c741e295348def11db 129 Pfam PF05942 Archaeal PaREP1/PaREP8 family 7 111 8.0E-22 T 31-10-2018 IPR010268 Archaeal PaREP1 DFR85_12235 8cc28a02822188c741e295348def11db 129 Gene3D G3DSA:1.20.120.330 2 122 2.9E-33 T 31-10-2018 DFR85_12000 c922f8c5eee1094826ae78978bc05999 189 Gene3D G3DSA:3.40.50.720 36 170 3.2E-15 T 31-10-2018 DFR85_12000 c922f8c5eee1094826ae78978bc05999 189 Pfam PF13478 XdhC Rossmann domain 39 164 1.3E-17 T 31-10-2018 IPR027051 XdhC Rossmann domain DFR85_08615 94c4acb5eaed8febd57d97edd98d901f 211 SUPERFAMILY SSF53790 12 210 4.97E-35 T 31-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 DFR85_08615 94c4acb5eaed8febd57d97edd98d901f 211 Gene3D G3DSA:3.40.1010.10 10 107 5.7E-15 T 31-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 DFR85_08615 94c4acb5eaed8febd57d97edd98d901f 211 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 14 196 3.4E-23 T 31-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 DFR85_08615 94c4acb5eaed8febd57d97edd98d901f 211 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 14 202 1.2E-28 T 31-10-2018 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 DFR85_06785 832f0cfbac35d50bf4b3ebbcfb55cb97 177 SUPERFAMILY SSF88723 8 69 3.04E-6 T 31-10-2018 IPR029060 PIN-like domain superfamily DFR85_06785 832f0cfbac35d50bf4b3ebbcfb55cb97 177 Gene3D G3DSA:3.40.50.1010 7 77 1.3E-5 T 31-10-2018 DFR85_06785 832f0cfbac35d50bf4b3ebbcfb55cb97 177 Pfam PF01927 Mut7-C RNAse domain 4 109 1.5E-27 T 31-10-2018 IPR002782 Mut7-C RNAse domain DFR85_06785 832f0cfbac35d50bf4b3ebbcfb55cb97 177 Pfam PF01927 Mut7-C RNAse domain 110 135 1.3E-5 T 31-10-2018 IPR002782 Mut7-C RNAse domain DFR85_00065 5f96eba2322041402b334c324169147a 393 Gene3D G3DSA:3.30.70.20 13 89 1.6E-6 T 31-10-2018 DFR85_00065 5f96eba2322041402b334c324169147a 393 SUPERFAMILY SSF54862 23 81 1.26E-7 T 31-10-2018 DFR85_00065 5f96eba2322041402b334c324169147a 393 Pfam PF02754 Cysteine-rich domain 291 364 0.015 T 31-10-2018 IPR004017 Cysteine-rich domain DFR85_00065 5f96eba2322041402b334c324169147a 393 Pfam PF02754 Cysteine-rich domain 165 248 1.3E-10 T 31-10-2018 IPR004017 Cysteine-rich domain DFR85_00065 5f96eba2322041402b334c324169147a 393 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 28 39 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR85_07015 ff8c3f6aaf74485afce75e0dadf387f7 151 Pfam PF01280 Ribosomal protein L19e 4 145 3.1E-43 T 31-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07015 ff8c3f6aaf74485afce75e0dadf387f7 151 Gene3D G3DSA:1.10.1200.60 92 148 1.0E-18 T 31-10-2018 IPR015974 Ribosomal protein L19/L19e, domain 3 GO:0003735|GO:0006412 DFR85_07015 ff8c3f6aaf74485afce75e0dadf387f7 151 Gene3D G3DSA:1.10.1650.10 1 56 4.6E-17 T 31-10-2018 IPR015972 Ribosomal protein L19/L19e, domain 1 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07015 ff8c3f6aaf74485afce75e0dadf387f7 151 SUPERFAMILY SSF48140 4 143 2.09E-41 T 31-10-2018 IPR035970 Ribosomal protein L19/L19e superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07015 ff8c3f6aaf74485afce75e0dadf387f7 151 Hamap MF_01475 50S ribosomal protein L19e [rpl19e]. 3 150 23.72 T 31-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07015 ff8c3f6aaf74485afce75e0dadf387f7 151 SMART SM01416 3 147 2.6E-59 T 31-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_11540 714fd6998de0422b6655e9385fc827e0 230 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 65 228 6.7E-45 T 31-10-2018 IPR020051 SagB-type dehydrogenase domain DFR85_11540 714fd6998de0422b6655e9385fc827e0 230 SUPERFAMILY SSF55469 45 228 3.53E-22 T 31-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 DFR85_11540 714fd6998de0422b6655e9385fc827e0 230 Gene3D G3DSA:3.40.109.10 18 230 1.7E-48 T 31-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 DFR85_11540 714fd6998de0422b6655e9385fc827e0 230 Pfam PF00881 Nitroreductase family 49 228 9.3E-22 T 31-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 DFR85_06750 92a204348008e2c0cbfcf07489a4ffc6 364 Pfam PF01266 FAD dependent oxidoreductase 3 334 4.2E-42 T 31-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 DFR85_06750 92a204348008e2c0cbfcf07489a4ffc6 364 Gene3D G3DSA:3.50.50.60 3 337 1.4E-58 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_06750 92a204348008e2c0cbfcf07489a4ffc6 364 Gene3D G3DSA:3.30.9.10 82 293 1.4E-58 T 31-10-2018 DFR85_06750 92a204348008e2c0cbfcf07489a4ffc6 364 SUPERFAMILY SSF51905 1 357 2.07E-32 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_06290 be06e0a88c869b7a4694d0b8652ef807 468 PIRSF PIRSF006060 1 463 4.4E-44 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_06290 be06e0a88c869b7a4694d0b8652ef807 468 Gene3D G3DSA:1.20.1740.10 3 441 2.9E-24 T 31-10-2018 DFR85_06290 be06e0a88c869b7a4694d0b8652ef807 468 Pfam PF13520 Amino acid permease 17 419 4.3E-13 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_15040 b292302842bb8e82a29e5ed17a469612 416 Pfam PF13173 AAA domain 35 164 5.9E-29 T 31-10-2018 DFR85_15040 b292302842bb8e82a29e5ed17a469612 416 Pfam PF13635 Domain of unknown function (DUF4143) 272 364 9.5E-8 T 31-10-2018 IPR025420 Domain of unknown function DUF4143 DFR85_15040 b292302842bb8e82a29e5ed17a469612 416 SUPERFAMILY SSF52540 33 169 1.82E-15 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_01795 2fd869f0cb5996ec4edc9a30f74bee3b 118 Gene3D G3DSA:3.30.420.130 1 103 5.1E-7 T 31-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily DFR85_01795 2fd869f0cb5996ec4edc9a30f74bee3b 118 SUPERFAMILY SSF53146 1 95 2.09E-7 T 31-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily DFR85_00990 cf6fb366eff69f3c3d3afeec413403db 140 Gene3D G3DSA:1.20.120.330 29 139 3.2E-6 T 31-10-2018 DFR85_00990 cf6fb366eff69f3c3d3afeec413403db 140 Pfam PF05942 Archaeal PaREP1/PaREP8 family 35 129 1.1E-5 T 31-10-2018 IPR010268 Archaeal PaREP1 DFR85_10420 a9505ce636c1b36bea0ed58ad2c7c619 118 SUPERFAMILY SSF49764 40 117 7.5E-9 T 31-10-2018 IPR008978 HSP20-like chaperone DFR85_07705 e363dcf8705910a790826ea6412ba859 216 Hamap MF_01218_A Uracil phosphoribosyltransferase [upp]. 1 216 40.589 T 31-10-2018 IPR034331 Uracil phosphoribosyltransferase, archaea GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 DFR85_07705 e363dcf8705910a790826ea6412ba859 216 Pfam PF14681 Uracil phosphoribosyltransferase 7 216 6.9E-47 T 31-10-2018 DFR85_07705 e363dcf8705910a790826ea6412ba859 216 Gene3D G3DSA:3.40.50.2020 3 216 2.1E-60 T 31-10-2018 DFR85_07705 e363dcf8705910a790826ea6412ba859 216 SUPERFAMILY SSF53271 4 216 5.64E-58 T 31-10-2018 IPR029057 Phosphoribosyltransferase-like DFR85_03255 0941581793ddc64c82804999e0f905de 452 SUPERFAMILY SSF103473 11 443 6.93E-45 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_03255 0941581793ddc64c82804999e0f905de 452 Pfam PF00083 Sugar (and other) transporter 21 443 2.1E-31 T 31-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 DFR85_03255 0941581793ddc64c82804999e0f905de 452 ProSitePatterns PS00217 Sugar transport proteins signature 2. 118 143 - T 31-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DFR85_12200 2946cb79b41974ebb9ca98118985fe6c 399 Pfam PF07690 Major Facilitator Superfamily 15 322 4.7E-11 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_12200 2946cb79b41974ebb9ca98118985fe6c 399 Gene3D G3DSA:1.20.1250.20 7 198 1.2E-8 T 31-10-2018 DFR85_12200 2946cb79b41974ebb9ca98118985fe6c 399 Gene3D G3DSA:1.20.1250.20 217 393 1.7E-10 T 31-10-2018 DFR85_12200 2946cb79b41974ebb9ca98118985fe6c 399 SUPERFAMILY SSF103473 1 392 1.27E-27 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_14480 1ae467444408f85f812524d8786378d6 130 Gene3D G3DSA:1.10.10.10 2 112 2.8E-18 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_14480 1ae467444408f85f812524d8786378d6 130 SUPERFAMILY SSF46785 3 81 2.67E-20 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_14480 1ae467444408f85f812524d8786378d6 130 Pfam PF03551 Transcriptional regulator PadR-like family 13 77 1.2E-11 T 31-10-2018 IPR005149 Transcription regulator PadR, N-terminal DFR85_03295 095ed52b0d10045115ad7af2eb867292 259 Pfam PF04055 Radical SAM superfamily 28 193 1.0E-9 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR85_00365 c66bbf6728b0e7a9bb3bc8efd350ee52 399 Gene3D G3DSA:1.20.1250.20 8 399 3.2E-51 T 31-10-2018 DFR85_00365 c66bbf6728b0e7a9bb3bc8efd350ee52 399 SUPERFAMILY SSF103473 7 390 4.45E-48 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_00365 c66bbf6728b0e7a9bb3bc8efd350ee52 399 ProSitePatterns PS00216 Sugar transport proteins signature 1. 268 285 - T 31-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DFR85_00365 c66bbf6728b0e7a9bb3bc8efd350ee52 399 Pfam PF07690 Major Facilitator Superfamily 38 345 6.5E-21 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_04715 8588e9a67cb9f99033a63db29f608704 138 Gene3D G3DSA:3.40.50.1010 1 136 5.0E-14 T 31-10-2018 DFR85_04715 8588e9a67cb9f99033a63db29f608704 138 SUPERFAMILY SSF88723 2 135 5.05E-16 T 31-10-2018 IPR029060 PIN-like domain superfamily DFR85_04715 8588e9a67cb9f99033a63db29f608704 138 Pfam PF01850 PIN domain 2 126 6.0E-10 T 31-10-2018 IPR002716 PIN domain DFR85_04715 8588e9a67cb9f99033a63db29f608704 138 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 1 133 9.767 T 31-10-2018 IPR022907 VapC family GO:0004540 DFR85_03380 17f280939584100454fca3dad9de3baf 476 Pfam PF13520 Amino acid permease 24 456 1.8E-20 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_03380 17f280939584100454fca3dad9de3baf 476 PIRSF PIRSF006060 4 474 3.8E-55 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_03380 17f280939584100454fca3dad9de3baf 476 Gene3D G3DSA:1.20.1740.10 16 475 7.9E-42 T 31-10-2018 DFR85_07485 8ca8f3a195eff9b6283062f0ab0e0739 217 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 34 205 3.5E-22 T 31-10-2018 IPR013343 CRISPR-associated protein Cas4 DFR85_07485 8ca8f3a195eff9b6283062f0ab0e0739 217 Pfam PF01930 Domain of unknown function DUF83 36 204 8.1E-7 T 31-10-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 DFR85_07485 8ca8f3a195eff9b6283062f0ab0e0739 217 Gene3D G3DSA:3.90.320.10 8 209 2.5E-65 T 31-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal DFR85_06440 03a05b084be57e0eb1a46ed533781d92 325 Pfam PF01435 Peptidase family M48 84 320 2.9E-31 T 31-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 DFR85_06440 03a05b084be57e0eb1a46ed533781d92 325 Gene3D G3DSA:3.30.2010.10 72 163 3.1E-20 T 31-10-2018 DFR85_06440 03a05b084be57e0eb1a46ed533781d92 325 Hamap MF_00188 Protease HtpX [htpX]. 7 320 27.931 T 31-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 DFR85_15675 059f813885a30169b45f24d295740d97 153 Pfam PF00583 Acetyltransferase (GNAT) family 40 142 1.8E-15 T 31-10-2018 IPR000182 GNAT domain DFR85_15675 059f813885a30169b45f24d295740d97 153 Gene3D G3DSA:3.40.630.30 1 149 3.1E-23 T 31-10-2018 DFR85_15675 059f813885a30169b45f24d295740d97 153 SUPERFAMILY SSF55729 1 147 2.95E-24 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase DFR85_04540 cad033dc5e40c0267602d41634c8a39c 351 Pfam PF01609 Transposase DDE domain 152 278 7.2E-7 T 31-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 DFR85_04540 cad033dc5e40c0267602d41634c8a39c 351 Pfam PF14210 Domain of unknown function (DUF4322) 2 67 9.7E-40 T 31-10-2018 IPR025471 Domain of unknown function DUF4322 DFR85_13095 85c38c3cfbb9438c998a9015154b48e5 91 Pfam PF02635 DsrE/DsrF-like family 40 90 1.3E-8 T 31-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein DFR85_13095 85c38c3cfbb9438c998a9015154b48e5 91 SUPERFAMILY SSF75169 4 90 9.13E-17 T 31-10-2018 IPR027396 DsrEFH-like DFR85_13095 85c38c3cfbb9438c998a9015154b48e5 91 Gene3D G3DSA:3.40.1260.10 1 91 3.8E-17 T 31-10-2018 IPR027396 DsrEFH-like DFR85_12330 f0c94aa2d4dda27178c13b619cbf7ffa 230 SUPERFAMILY SSF53335 9 209 6.75E-39 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR85_12330 f0c94aa2d4dda27178c13b619cbf7ffa 230 Gene3D G3DSA:3.40.50.150 2 230 2.6E-59 T 31-10-2018 DFR85_12330 f0c94aa2d4dda27178c13b619cbf7ffa 230 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 11 196 1.3E-41 T 31-10-2018 DFR85_08130 b3d0e4606fa93a321a7cd37c482e31aa 572 SUPERFAMILY SSF52540 151 547 3.08E-26 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_08130 b3d0e4606fa93a321a7cd37c482e31aa 572 Pfam PF01935 Domain of unknown function DUF87 156 417 8.0E-21 T 31-10-2018 IPR002789 Helicase HerA, central domain DFR85_08130 b3d0e4606fa93a321a7cd37c482e31aa 572 Gene3D G3DSA:3.40.50.300 143 292 7.7E-17 T 31-10-2018 DFR85_08130 b3d0e4606fa93a321a7cd37c482e31aa 572 Gene3D G3DSA:3.40.50.300 346 565 1.7E-23 T 31-10-2018 DFR85_13550 c2baf79f0b66a59fba17fe04d3e8dbc3 197 SUPERFAMILY SSF102198 2 196 2.49E-52 T 31-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 DFR85_13550 c2baf79f0b66a59fba17fe04d3e8dbc3 197 Gene3D G3DSA:3.50.30.50 1 197 1.6E-59 T 31-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 DFR85_13550 c2baf79f0b66a59fba17fe04d3e8dbc3 197 Pfam PF04199 Putative cyclase 3 142 1.1E-20 T 31-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 DFR85_14500 3590898db689911b600d8461ec7e476e 245 Pfam PF06157 Protein of unknown function (DUF973) 20 244 8.9E-25 T 31-10-2018 IPR009321 Protein of unknown function DUF973 DFR85_03160 80630ba5cfd5998d79b7fa36d04f09ae 474 Gene3D G3DSA:3.40.190.10 44 465 5.0E-35 T 31-10-2018 DFR85_03160 80630ba5cfd5998d79b7fa36d04f09ae 474 SUPERFAMILY SSF53850 46 466 2.36E-31 T 31-10-2018 DFR85_03160 80630ba5cfd5998d79b7fa36d04f09ae 474 Pfam PF13416 Bacterial extracellular solute-binding protein 69 394 8.2E-10 T 31-10-2018 IPR006059 Bacterial extracellular solute-binding protein DFR85_02200 14e326e421892d09ea9f24d033e9bd62 136 Pfam PF11485 Protein of unknown function (DUF3211) 3 136 1.4E-46 T 31-10-2018 IPR021578 Protein of unknown function DUF3211 DFR85_02200 14e326e421892d09ea9f24d033e9bd62 136 Gene3D G3DSA:3.30.530.20 1 136 3.7E-47 T 31-10-2018 IPR023393 START-like domain superfamily DFR85_04375 23762c1420a6398a0629dd45f3d80b5b 350 SUPERFAMILY SSF53448 87 302 1.35E-5 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_13545 5d40b2e4413f25a2b22ccda6df8435cb 227 Gene3D G3DSA:3.30.1020.20 149 227 1.4E-26 T 31-10-2018 DFR85_13545 5d40b2e4413f25a2b22ccda6df8435cb 227 Hamap MF_00401 Peroxiredoxin. 8 215 49.846 T 31-10-2018 IPR022915 Peroxiredoxin, TDXH subfamily GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 DFR85_13545 5d40b2e4413f25a2b22ccda6df8435cb 227 SUPERFAMILY SSF52833 8 217 4.06E-64 T 31-10-2018 IPR036249 Thioredoxin-like superfamily DFR85_13545 5d40b2e4413f25a2b22ccda6df8435cb 227 Gene3D G3DSA:3.40.30.10 9 148 7.3E-45 T 31-10-2018 DFR85_13545 5d40b2e4413f25a2b22ccda6df8435cb 227 Pfam PF00578 AhpC/TSA family 10 139 4.8E-31 T 31-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 DFR85_13545 5d40b2e4413f25a2b22ccda6df8435cb 227 PIRSF PIRSF000239 3 222 8.2E-77 T 31-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 DFR85_13545 5d40b2e4413f25a2b22ccda6df8435cb 227 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 160 200 3.4E-7 T 31-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 DFR85_02710 d8b280164bb6f3d7fc5d171ae07cb51d 338 SUPERFAMILY SSF53383 6 336 8.8E-70 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase DFR85_02710 d8b280164bb6f3d7fc5d171ae07cb51d 338 Gene3D G3DSA:3.90.1150.10 6 333 1.8E-83 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 DFR85_02710 d8b280164bb6f3d7fc5d171ae07cb51d 338 Gene3D G3DSA:3.40.640.10 26 235 1.8E-83 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR85_02710 d8b280164bb6f3d7fc5d171ae07cb51d 338 Pfam PF00155 Aminotransferase class I and II 33 333 1.4E-22 T 31-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 DFR85_08435 3053162cf5bd9448a7a8ebb69b84f68c 180 Pfam PF09335 SNARE associated Golgi protein 10 135 3.0E-16 T 31-10-2018 IPR032816 SNARE associated Golgi protein DFR85_10015 c61420f9f239dbfcf1038f411c433a7d 275 Gene3D G3DSA:1.10.443.10 103 274 6.3E-53 T 31-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 DFR85_10015 c61420f9f239dbfcf1038f411c433a7d 275 Hamap MF_02055 Tyrosine recombinase XerA [xerA]. 11 274 46.343 T 31-10-2018 IPR033686 Tyrosine recombinase XerA DFR85_10015 c61420f9f239dbfcf1038f411c433a7d 275 Gene3D G3DSA:1.10.150.130 10 102 2.0E-10 T 31-10-2018 IPR010998 Integrase/recombinase, N-terminal DFR85_10015 c61420f9f239dbfcf1038f411c433a7d 275 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 14 66 6.9E-7 T 31-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 DFR85_10015 c61420f9f239dbfcf1038f411c433a7d 275 Pfam PF00589 Phage integrase family 111 261 3.5E-40 T 31-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 DFR85_10015 c61420f9f239dbfcf1038f411c433a7d 275 SUPERFAMILY SSF56349 12 270 5.89E-55 T 31-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 DFR85_09215 701063cce00b930516e658355a539178 197 SUPERFAMILY SSF74784 7 191 3.66E-20 T 31-10-2018 IPR036081 Translin superfamily GO:0043565 Reactome: R-HSA-426486 DFR85_09215 701063cce00b930516e658355a539178 197 Gene3D G3DSA:1.20.58.2140 7 197 1.8E-52 T 31-10-2018 DFR85_04300 e8d6535b7b58bdd7b71d1f393f5be33b 287 SUPERFAMILY SSF53448 4 163 2.15E-25 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_04300 e8d6535b7b58bdd7b71d1f393f5be33b 287 Pfam PF00535 Glycosyl transferase family 2 5 103 3.2E-17 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 DFR85_04300 e8d6535b7b58bdd7b71d1f393f5be33b 287 Gene3D G3DSA:3.90.550.10 2 182 3.3E-23 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_15525 dbabb31a6eb6405a6a9f7751693b4f6a 155 PIRSF PIRSF000239 1 141 8.1E-29 T 31-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 DFR85_15525 dbabb31a6eb6405a6a9f7751693b4f6a 155 Gene3D G3DSA:3.40.30.10 1 151 1.6E-51 T 31-10-2018 DFR85_15525 dbabb31a6eb6405a6a9f7751693b4f6a 155 Pfam PF00578 AhpC/TSA family 4 131 7.9E-36 T 31-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 DFR85_15525 dbabb31a6eb6405a6a9f7751693b4f6a 155 SUPERFAMILY SSF52833 1 154 1.26E-50 T 31-10-2018 IPR036249 Thioredoxin-like superfamily DFR85_12955 cc0f730b1949d31b00cf4116bdef94d5 268 Gene3D G3DSA:2.40.40.20 152 268 1.6E-18 T 31-10-2018 DFR85_12955 cc0f730b1949d31b00cf4116bdef94d5 268 SUPERFAMILY SSF50692 158 268 7.69E-21 T 31-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily DFR85_12955 cc0f730b1949d31b00cf4116bdef94d5 268 SUPERFAMILY SSF53706 1 152 1.02E-42 T 31-10-2018 DFR85_12955 cc0f730b1949d31b00cf4116bdef94d5 268 Gene3D G3DSA:3.40.50.740 1 123 9.7E-43 T 31-10-2018 DFR85_12955 cc0f730b1949d31b00cf4116bdef94d5 268 Pfam PF01568 Molydopterin dinucleotide binding domain 162 261 9.0E-19 T 31-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 DFR85_12955 cc0f730b1949d31b00cf4116bdef94d5 268 Pfam PF00384 Molybdopterin oxidoreductase 1 87 1.9E-24 T 31-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_06360 e83909e3d094d9b012b1a956a96bd6c3 237 SUPERFAMILY SSF56235 2 232 2.7E-10 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR85_06360 e83909e3d094d9b012b1a956a96bd6c3 237 Pfam PF13230 Glutamine amidotransferases class-II 1 150 5.5E-8 T 31-10-2018 IPR026869 Putative glutamine amidotransferase type 2 DFR85_06360 e83909e3d094d9b012b1a956a96bd6c3 237 Gene3D G3DSA:3.60.20.10 1 213 8.7E-17 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR85_01310 1319114faaf4f1265d1ea284d4ef1d57 164 SUPERFAMILY SSF54631 3 125 1.52E-32 T 31-10-2018 DFR85_01310 1319114faaf4f1265d1ea284d4ef1d57 164 Gene3D G3DSA:3.10.580.10 1 157 1.8E-36 T 31-10-2018 DFR85_01310 1319114faaf4f1265d1ea284d4ef1d57 164 SMART SM00116 75 123 4.3E-15 T 31-10-2018 IPR000644 CBS domain DFR85_01310 1319114faaf4f1265d1ea284d4ef1d57 164 SMART SM00116 12 60 9.0E-7 T 31-10-2018 IPR000644 CBS domain DFR85_01310 1319114faaf4f1265d1ea284d4ef1d57 164 Pfam PF00571 CBS domain 68 123 5.1E-16 T 31-10-2018 IPR000644 CBS domain DFR85_01310 1319114faaf4f1265d1ea284d4ef1d57 164 Pfam PF00571 CBS domain 5 60 1.4E-9 T 31-10-2018 IPR000644 CBS domain DFR85_08330 03b4c1c3c2a515e7befb9452c1391663 164 Pfam PF02926 THUMP domain 20 150 3.2E-8 T 31-10-2018 IPR004114 THUMP domain GO:0003723 DFR85_08330 03b4c1c3c2a515e7befb9452c1391663 164 SUPERFAMILY SSF143437 93 151 5.23E-5 T 31-10-2018 DFR85_05815 55a94f579f659f9292a527f7bdb8fe9a 198 Gene3D G3DSA:3.30.2170.10 9 198 1.7E-39 T 31-10-2018 DFR85_05815 55a94f579f659f9292a527f7bdb8fe9a 198 Pfam PF04493 Endonuclease V 20 180 1.1E-33 T 31-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 DFR85_10500 ac61b11113dec3dbdf8e183df54fa966 372 Gene3D G3DSA:3.90.1150.10 2 346 6.1E-89 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 DFR85_10500 ac61b11113dec3dbdf8e183df54fa966 372 Gene3D G3DSA:3.40.640.10 11 252 6.1E-89 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR85_10500 ac61b11113dec3dbdf8e183df54fa966 372 PIRSF PIRSF000524 1 359 8.1E-81 T 31-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 DFR85_10500 ac61b11113dec3dbdf8e183df54fa966 372 SUPERFAMILY SSF53383 2 349 8.95E-75 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase DFR85_10500 ac61b11113dec3dbdf8e183df54fa966 372 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 176 196 - T 31-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site DFR85_10500 ac61b11113dec3dbdf8e183df54fa966 372 Pfam PF00266 Aminotransferase class-V 21 327 6.8E-25 T 31-10-2018 IPR000192 Aminotransferase class V domain DFR85_00320 2702496d6706489188d8bdd8eb0ed479 230 TIGRFAM TIGR00266 TIGR00266: TIGR00266 family protein 3 220 9.0E-39 T 31-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 DFR85_00320 2702496d6706489188d8bdd8eb0ed479 230 Pfam PF01987 Mitochondrial biogenesis AIM24 4 204 4.4E-49 T 31-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 DFR85_00320 2702496d6706489188d8bdd8eb0ed479 230 Gene3D G3DSA:3.60.160.10 2 223 2.6E-64 T 31-10-2018 IPR036983 Mitochondrial biogenesis AIM24 superfamily DFR85_00320 2702496d6706489188d8bdd8eb0ed479 230 SUPERFAMILY SSF51219 2 223 9.68E-61 T 31-10-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain superfamily DFR85_00740 1a2df4bb0dff4cc847c5379cc6a34c67 58 Pfam PF01402 Ribbon-helix-helix protein, copG family 4 37 7.4E-8 T 31-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 DFR85_00740 1a2df4bb0dff4cc847c5379cc6a34c67 58 SUPERFAMILY SSF47598 1 42 1.61E-6 T 31-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 DFR85_00740 1a2df4bb0dff4cc847c5379cc6a34c67 58 Gene3D G3DSA:1.10.1220.10 9 42 4.1E-5 T 31-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 DFR85_11995 530ff1c16aacff5ec94cb6c08f4759fd 135 Pfam PF01980 Uncharacterised protein family UPF0066 15 113 8.4E-33 T 31-10-2018 IPR023370 YaeB-like, N-terminal domain DFR85_11995 530ff1c16aacff5ec94cb6c08f4759fd 135 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 13 120 1.7E-30 T 31-10-2018 IPR023370 YaeB-like, N-terminal domain DFR85_11995 530ff1c16aacff5ec94cb6c08f4759fd 135 Gene3D G3DSA:2.40.30.70 2 116 2.8E-35 T 31-10-2018 IPR036414 YaeB, N-terminal domain superfamily DFR85_11995 530ff1c16aacff5ec94cb6c08f4759fd 135 SUPERFAMILY SSF118196 3 131 1.7E-40 T 31-10-2018 IPR036413 YaeB-like superfamily DFR85_12300 c5c75c2604c88c4ef1de7d307d100ee1 226 Gene3D G3DSA:3.60.15.10 2 225 2.9E-41 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR85_12300 c5c75c2604c88c4ef1de7d307d100ee1 226 SUPERFAMILY SSF56281 2 224 1.31E-39 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR85_12300 c5c75c2604c88c4ef1de7d307d100ee1 226 Pfam PF00753 Metallo-beta-lactamase superfamily 22 217 5.9E-22 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR85_12300 c5c75c2604c88c4ef1de7d307d100ee1 226 SMART SM00849 24 219 1.8E-23 T 31-10-2018 IPR001279 Metallo-beta-lactamase DFR85_11395 7644fc8f9281f9b235b7edd2f7b7acd5 186 SUPERFAMILY SSF52833 101 176 3.84E-13 T 31-10-2018 IPR036249 Thioredoxin-like superfamily DFR85_11395 7644fc8f9281f9b235b7edd2f7b7acd5 186 Gene3D G3DSA:3.40.30.80 1 172 6.8E-55 T 31-10-2018 DFR85_11395 7644fc8f9281f9b235b7edd2f7b7acd5 186 Pfam PF13192 Thioredoxin domain 100 167 4.5E-12 T 31-10-2018 IPR012336 Thioredoxin-like fold DFR85_15625 d6cbff5d5c5260b305494fe5474436a1 129 SMART SM00116 73 120 0.057 T 31-10-2018 IPR000644 CBS domain DFR85_15625 d6cbff5d5c5260b305494fe5474436a1 129 SMART SM00116 10 57 4.3E-11 T 31-10-2018 IPR000644 CBS domain DFR85_15625 d6cbff5d5c5260b305494fe5474436a1 129 Gene3D G3DSA:3.10.580.10 1 128 2.2E-30 T 31-10-2018 DFR85_15625 d6cbff5d5c5260b305494fe5474436a1 129 Pfam PF00571 CBS domain 68 117 5.4E-6 T 31-10-2018 IPR000644 CBS domain DFR85_15625 d6cbff5d5c5260b305494fe5474436a1 129 Pfam PF00571 CBS domain 3 57 2.1E-13 T 31-10-2018 IPR000644 CBS domain DFR85_15625 d6cbff5d5c5260b305494fe5474436a1 129 SUPERFAMILY SSF54631 1 119 6.7E-29 T 31-10-2018 DFR85_14125 980a68c11337af060dbc77d7111f1060 117 Pfam PF01638 HxlR-like helix-turn-helix 22 106 4.5E-17 T 31-10-2018 IPR002577 Helix-turn-helix, HxlR type DFR85_14125 980a68c11337af060dbc77d7111f1060 117 SUPERFAMILY SSF46785 17 104 1.6E-17 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_14125 980a68c11337af060dbc77d7111f1060 117 Gene3D G3DSA:1.10.10.10 11 111 2.1E-18 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_12515 4ebd10caddaba8fa4968778bbf9a8cb7 164 Pfam PF08909 Domain of unknown function (DUF1854) 47 162 4.4E-20 T 31-10-2018 IPR015005 Domain of unknown function DUF1854 DFR85_05955 49cebedfaad398f2074d9e1de90291b8 349 SUPERFAMILY SSF53187 129 289 2.05E-15 T 31-10-2018 DFR85_05955 49cebedfaad398f2074d9e1de90291b8 349 Pfam PF04389 Peptidase family M28 154 291 2.1E-5 T 31-10-2018 IPR007484 Peptidase M28 DFR85_05955 49cebedfaad398f2074d9e1de90291b8 349 Gene3D G3DSA:3.40.630.10 113 311 2.0E-12 T 31-10-2018 DFR85_10205 b06eb37a98a984acc596364453f6b016 129 Pfam PF02675 S-adenosylmethionine decarboxylase 19 126 4.4E-34 T 31-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 DFR85_10205 b06eb37a98a984acc596364453f6b016 129 SUPERFAMILY SSF56276 14 127 3.14E-33 T 31-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 DFR85_10205 b06eb37a98a984acc596364453f6b016 129 Gene3D G3DSA:3.60.90.10 2 129 2.1E-37 T 31-10-2018 DFR85_10205 b06eb37a98a984acc596364453f6b016 129 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 15 127 2.7E-39 T 31-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 DFR85_10205 b06eb37a98a984acc596364453f6b016 129 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 13 129 25.788 T 31-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 DFR85_10205 b06eb37a98a984acc596364453f6b016 129 Hamap MF_01298 Arginine decarboxylase proenzyme. 5 128 46.804 T 31-10-2018 IPR027549 Arginine decarboxylase proenzyme GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 DFR85_13705 e3e462a70d7b131ba6d8ad88c61593fb 114 Pfam PF09941 Uncharacterized conserved protein (DUF2173) 6 109 1.8E-40 T 31-10-2018 IPR018685 Protein of unknown function DUF2173 DFR85_13705 e3e462a70d7b131ba6d8ad88c61593fb 114 PIRSF PIRSF006821 1 112 1.5E-50 T 31-10-2018 IPR018685 Protein of unknown function DUF2173 DFR85_08815 58a46daad2b3e8d823d65d587f1fc2f8 358 Gene3D G3DSA:2.30.42.10 201 278 5.4E-6 T 31-10-2018 DFR85_08815 58a46daad2b3e8d823d65d587f1fc2f8 358 SUPERFAMILY SSF50156 201 285 1.6E-8 T 31-10-2018 IPR036034 PDZ superfamily GO:0005515 DFR85_08815 58a46daad2b3e8d823d65d587f1fc2f8 358 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 154 166 2.3E-19 T 31-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 DFR85_08815 58a46daad2b3e8d823d65d587f1fc2f8 358 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 122 136 2.3E-19 T 31-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 DFR85_08815 58a46daad2b3e8d823d65d587f1fc2f8 358 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 99 118 2.3E-19 T 31-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 DFR85_08815 58a46daad2b3e8d823d65d587f1fc2f8 358 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 138 153 2.3E-19 T 31-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 DFR85_08815 58a46daad2b3e8d823d65d587f1fc2f8 358 Pfam PF02163 Peptidase family M50 114 345 1.8E-19 T 31-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 DFR85_00815 4508ab0fe444b9d978172d04b5eca30d 553 Pfam PF01642 Methylmalonyl-CoA mutase 30 545 2.2E-210 T 31-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 DFR85_00815 4508ab0fe444b9d978172d04b5eca30d 553 SUPERFAMILY SSF51703 8 547 8.37E-204 T 31-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 DFR85_00815 4508ab0fe444b9d978172d04b5eca30d 553 Gene3D G3DSA:3.20.20.240 2 553 1.8E-235 T 31-10-2018 DFR85_00815 4508ab0fe444b9d978172d04b5eca30d 553 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 29 552 2.2E-228 T 31-10-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 DFR85_02210 6d39b7e5870f662c1f8a96cfbb70bbac 280 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 13 250 6.9E-75 T 31-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region DFR85_02210 6d39b7e5870f662c1f8a96cfbb70bbac 280 Gene3D G3DSA:2.120.10.30 2 278 2.8E-85 T 31-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like DFR85_02210 6d39b7e5870f662c1f8a96cfbb70bbac 280 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 125 147 4.8E-39 T 31-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) DFR85_02210 6d39b7e5870f662c1f8a96cfbb70bbac 280 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 188 205 4.8E-39 T 31-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) DFR85_02210 6d39b7e5870f662c1f8a96cfbb70bbac 280 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 84 105 4.8E-39 T 31-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) DFR85_02210 6d39b7e5870f662c1f8a96cfbb70bbac 280 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 231 249 4.8E-39 T 31-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) DFR85_02210 6d39b7e5870f662c1f8a96cfbb70bbac 280 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 148 168 4.8E-39 T 31-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) DFR85_02210 6d39b7e5870f662c1f8a96cfbb70bbac 280 SUPERFAMILY SSF63829 9 274 2.62E-60 T 31-10-2018 DFR85_13310 173eb62e2f79c0198676721f8833bddf 1095 Pfam PF04465 Protein of unknown function (DUF499) 111 1091 3.9E-120 T 31-10-2018 IPR007555 Protein of unknown function DUF499 DFR85_12430 759c7af3b75642a9ca521d358562b838 220 SUPERFAMILY SSF117396 1 215 7.06E-55 T 31-10-2018 IPR036520 UPF0759 superfamily DFR85_12430 759c7af3b75642a9ca521d358562b838 220 Gene3D G3DSA:3.20.20.410 1 217 1.8E-46 T 31-10-2018 IPR036520 UPF0759 superfamily DFR85_12430 759c7af3b75642a9ca521d358562b838 220 Pfam PF01904 Protein of unknown function DUF72 16 212 1.8E-38 T 31-10-2018 IPR002763 Protein of unknown function DUF72 DFR85_05430 5728507b9f16d3be763c595d35d9ffee 146 SUPERFAMILY SSF88697 2 142 2.49E-29 T 31-10-2018 IPR015947 PUA-like superfamily DFR85_05430 5728507b9f16d3be763c595d35d9ffee 146 Pfam PF01878 EVE domain 2 141 1.0E-18 T 31-10-2018 IPR002740 EVE domain DFR85_05430 5728507b9f16d3be763c595d35d9ffee 146 Gene3D G3DSA:3.10.590.10 1 143 1.0E-32 T 31-10-2018 DFR85_00270 a9696f562f106372cc49aea134174038 372 Pfam PF07690 Major Facilitator Superfamily 21 208 1.8E-17 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_00270 a9696f562f106372cc49aea134174038 372 Gene3D G3DSA:1.20.1250.20 2 369 1.6E-36 T 31-10-2018 DFR85_00270 a9696f562f106372cc49aea134174038 372 SUPERFAMILY SSF103473 7 368 1.7E-40 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_12320 311364f5b3dc0a68d57961ebdc3016b8 168 SMART SM00506 2 132 6.9E-47 T 31-10-2018 IPR002589 Macro domain DFR85_12320 311364f5b3dc0a68d57961ebdc3016b8 168 Gene3D G3DSA:3.40.220.10 1 164 2.9E-59 T 31-10-2018 DFR85_12320 311364f5b3dc0a68d57961ebdc3016b8 168 SUPERFAMILY SSF52949 2 166 1.68E-57 T 31-10-2018 DFR85_12320 311364f5b3dc0a68d57961ebdc3016b8 168 Pfam PF01661 Macro domain 19 132 3.6E-38 T 31-10-2018 IPR002589 Macro domain DFR85_00295 eb5876796a21ef03fe102b14962df0e7 265 PIRSF PIRSF006648 4 254 1.6E-15 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 DFR85_00295 eb5876796a21ef03fe102b14962df0e7 265 Pfam PF01061 ABC-2 type transporter 19 219 1.8E-12 T 31-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 DFR85_13680 16e1cc372e959fcfc870d34734f259c5 395 SUPERFAMILY SSF58104 37 265 4.97E-10 T 31-10-2018 DFR85_13680 16e1cc372e959fcfc870d34734f259c5 395 Gene3D G3DSA:1.25.40.10 34 314 1.4E-7 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 DFR85_00700 fb97d3a996668dd72e2a97ed9cb976d8 247 PIRSF PIRSF016896 1 245 4.9E-64 T 31-10-2018 IPR012043 Pantoate kinase KEGG: 00770+2.7.1.169|MetaCyc: PWY-6654 DFR85_00700 fb97d3a996668dd72e2a97ed9cb976d8 247 SUPERFAMILY SSF54211 24 141 7.59E-10 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold DFR85_00700 fb97d3a996668dd72e2a97ed9cb976d8 247 Pfam PF00288 GHMP kinases N terminal domain 77 134 2.3E-5 T 31-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 DFR85_12770 133cdcb4a62ae20a9df68016d305d79d 286 SUPERFAMILY SSF51905 2 142 3.45E-10 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_12770 133cdcb4a62ae20a9df68016d305d79d 286 Gene3D G3DSA:3.50.50.60 3 266 4.4E-21 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_04450 adf3ccd4c91b82ee51cfd05bd7dca8fc 400 SUPERFAMILY SSF53448 46 327 6.57E-34 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_04450 adf3ccd4c91b82ee51cfd05bd7dca8fc 400 Gene3D G3DSA:3.90.550.10 38 254 9.7E-25 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_04450 adf3ccd4c91b82ee51cfd05bd7dca8fc 400 Pfam PF13632 Glycosyl transferase family group 2 133 324 2.9E-19 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 DFR85_13505 b15beda50a89b316a71c8396284f42ff 281 Pfam PF03787 RAMP superfamily 19 217 2.0E-21 T 31-10-2018 IPR005537 CRISPR type III-associated RAMP protein DFR85_13505 b15beda50a89b316a71c8396284f42ff 281 TIGRFAM TIGR02581 cas_cyan_RAMP: CRISPR-associated RAMP protein, SSO1426 family 12 223 5.7E-60 T 31-10-2018 IPR013411 CRISPR-associated RAMP TM1809 DFR85_07915 b1e56de36c25c8ecc9ad724a732f7b4c 152 Pfam PF00312 Ribosomal protein S15 73 146 5.1E-12 T 31-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_07915 b1e56de36c25c8ecc9ad724a732f7b4c 152 Hamap MF_01343_A 30S ribosomal protein S15 [rpsO]. 1 147 33.28 T 31-10-2018 IPR023029 Ribosomal protein S15P Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07915 b1e56de36c25c8ecc9ad724a732f7b4c 152 ProSitePatterns PS00362 Ribosomal protein S15 signature. 96 126 - T 31-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_07915 b1e56de36c25c8ecc9ad724a732f7b4c 152 SUPERFAMILY SSF47060 64 141 1.44E-17 T 31-10-2018 IPR009068 S15/NS1, RNA-binding DFR85_07915 b1e56de36c25c8ecc9ad724a732f7b4c 152 Gene3D G3DSA:1.10.287.10 81 149 1.6E-27 T 31-10-2018 DFR85_07915 b1e56de36c25c8ecc9ad724a732f7b4c 152 SMART SM01386 1 58 3.2E-29 T 31-10-2018 IPR012606 Ribosomal protein S13/S15, N-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07915 b1e56de36c25c8ecc9ad724a732f7b4c 152 SMART SM01387 68 147 1.2E-9 T 31-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 DFR85_07915 b1e56de36c25c8ecc9ad724a732f7b4c 152 Pfam PF08069 Ribosomal S13/S15 N-terminal domain 3 58 1.6E-22 T 31-10-2018 IPR012606 Ribosomal protein S13/S15, N-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07915 b1e56de36c25c8ecc9ad724a732f7b4c 152 Gene3D G3DSA:1.10.8.1030 34 80 7.2E-18 T 31-10-2018 DFR85_00440 194577bc4788592227a5aa9ce917005f 302 SMART SM00028 200 233 13.0 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 DFR85_00440 194577bc4788592227a5aa9ce917005f 302 SMART SM00028 7 40 5.5 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 DFR85_00440 194577bc4788592227a5aa9ce917005f 302 SMART SM00028 41 74 160.0 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 DFR85_00440 194577bc4788592227a5aa9ce917005f 302 Gene3D G3DSA:1.25.40.10 9 84 3.4E-8 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 DFR85_00440 194577bc4788592227a5aa9ce917005f 302 SUPERFAMILY SSF48452 8 160 7.94E-19 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 DFR85_00440 194577bc4788592227a5aa9ce917005f 302 Gene3D G3DSA:1.25.40.10 85 234 1.4E-8 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 DFR85_08020 5b30dcec3d20fa4d80688d8d2686278f 189 Gene3D G3DSA:3.90.950.10 6 187 9.9E-59 T 31-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like DFR85_08020 5b30dcec3d20fa4d80688d8d2686278f 189 Pfam PF01725 Ham1 family 8 182 1.6E-46 T 31-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 DFR85_08020 5b30dcec3d20fa4d80688d8d2686278f 189 SUPERFAMILY SSF52972 7 184 9.94E-55 T 31-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like DFR85_08020 5b30dcec3d20fa4d80688d8d2686278f 189 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 7 184 1.5E-54 T 31-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 DFR85_06975 b3b7975f469ae4865e77e50c3af0a230 87 PRINTS PR01250 Ribosomal protein L34 signature 19 36 3.4E-15 T 31-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_06975 b3b7975f469ae4865e77e50c3af0a230 87 PRINTS PR01250 Ribosomal protein L34 signature 54 76 3.4E-15 T 31-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_06975 b3b7975f469ae4865e77e50c3af0a230 87 PRINTS PR01250 Ribosomal protein L34 signature 6 19 3.4E-15 T 31-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_06975 b3b7975f469ae4865e77e50c3af0a230 87 PRINTS PR01250 Ribosomal protein L34 signature 37 47 3.4E-15 T 31-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_06975 b3b7975f469ae4865e77e50c3af0a230 87 Hamap MF_00349 50S ribosomal protein L34e [rpl34e]. 2 85 24.36 T 31-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_06975 b3b7975f469ae4865e77e50c3af0a230 87 ProSitePatterns PS01145 Ribosomal protein L34e signature. 8 21 - T 31-10-2018 IPR018065 Ribosomal protein L34e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_06975 b3b7975f469ae4865e77e50c3af0a230 87 Pfam PF01199 Ribosomal protein L34e 3 82 3.5E-17 T 31-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_06975 b3b7975f469ae4865e77e50c3af0a230 87 Gene3D G3DSA:3.40.1800.40 30 84 2.6E-10 T 31-10-2018 IPR038562 Ribosomal protein L34Ae superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_14855 d70825261e62231fff04d028c7ee13f6 195 Gene3D G3DSA:3.10.290.30 37 160 4.1E-6 T 31-10-2018 IPR024047 MM3350-like superfamily DFR85_14855 d70825261e62231fff04d028c7ee13f6 195 SUPERFAMILY SSF159941 41 151 2.35E-16 T 31-10-2018 IPR024047 MM3350-like superfamily DFR85_14855 d70825261e62231fff04d028c7ee13f6 195 Pfam PF07929 Plasmid pRiA4b ORF-3-like protein 53 147 3.4E-9 T 31-10-2018 IPR012912 Plasmid pRiA4b, Orf3 DFR85_11165 7996e335d1db884e5d7774c47365e71a 95 Hamap MF_01476 50S ribosomal protein L44e [rpl44e]. 1 91 23.71 T 31-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_11165 7996e335d1db884e5d7774c47365e71a 95 Gene3D G3DSA:3.10.450.80 1 95 9.6E-30 T 31-10-2018 DFR85_11165 7996e335d1db884e5d7774c47365e71a 95 Pfam PF00935 Ribosomal protein L44 16 90 2.7E-28 T 31-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_11165 7996e335d1db884e5d7774c47365e71a 95 ProDom PD002841 RIBOSOMAL RIBONUCLEOPROTEIN 60S L44 L44E L41 RESISTANCE 50S ANTIBIOTIC CYCLOHEXIMIDE 10 92 2.0E-36 T 31-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_11165 7996e335d1db884e5d7774c47365e71a 95 SUPERFAMILY SSF57829 1 91 2.56E-29 T 31-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 DFR85_01835 a9ad9fb03c7a8717ddef7aabd5e6132c 159 SUPERFAMILY SSF53448 1 154 1.15E-17 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_01835 a9ad9fb03c7a8717ddef7aabd5e6132c 159 Gene3D G3DSA:3.90.550.10 1 157 4.6E-21 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_01835 a9ad9fb03c7a8717ddef7aabd5e6132c 159 Pfam PF12804 MobA-like NTP transferase domain 1 102 2.3E-9 T 31-10-2018 IPR025877 MobA-like NTP transferase DFR85_02610 a2c35ff6f2a332704d41d8f5f3e6e5c4 266 Pfam PF03437 BtpA family 11 262 1.5E-71 T 31-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family DFR85_02610 a2c35ff6f2a332704d41d8f5f3e6e5c4 266 TIGRFAM TIGR00259 thylakoid_BtpA: membrane complex biogenesis protein, BtpA family 12 261 3.1E-70 T 31-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family DFR85_02610 a2c35ff6f2a332704d41d8f5f3e6e5c4 266 PIRSF PIRSF005956 1 266 5.7E-87 T 31-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family DFR85_02610 a2c35ff6f2a332704d41d8f5f3e6e5c4 266 SUPERFAMILY SSF51366 3 260 2.83E-19 T 31-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 DFR85_02610 a2c35ff6f2a332704d41d8f5f3e6e5c4 266 ProDom PD011184 BTPA I PHOTOSYSTEM BIOGENESIS ASSEMBLY SGCQ TRIPHOSPHATASE NUCLEOSIDE PAE3553 ENZYME 34 206 9.0E-32 T 31-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family DFR85_02610 a2c35ff6f2a332704d41d8f5f3e6e5c4 266 Gene3D G3DSA:3.20.20.70 133 266 5.0E-6 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_03145 bd540a711f9dc991193f5a4af4c83ead 533 Pfam PF13520 Amino acid permease 35 501 9.3E-33 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_03145 bd540a711f9dc991193f5a4af4c83ead 533 Gene3D G3DSA:1.20.1740.10 38 517 4.5E-10 T 31-10-2018 DFR85_03145 bd540a711f9dc991193f5a4af4c83ead 533 PIRSF PIRSF006060 3 527 7.6E-15 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_04145 a05283bf827f01b74468b901c030f7cc 231 Gene3D G3DSA:3.40.50.300 1 219 1.3E-59 T 31-10-2018 DFR85_04145 a05283bf827f01b74468b901c030f7cc 231 Pfam PF00005 ABC transporter 26 176 1.2E-31 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR85_04145 a05283bf827f01b74468b901c030f7cc 231 SUPERFAMILY SSF52540 3 215 2.28E-56 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_04145 a05283bf827f01b74468b901c030f7cc 231 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DFR85_04145 a05283bf827f01b74468b901c030f7cc 231 SMART SM00382 35 225 2.1E-10 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_14620 eaeea8139068ec332b5d5a0d322f6af6 531 SUPERFAMILY SSF56801 5 528 1.57E-126 T 31-10-2018 DFR85_14620 eaeea8139068ec332b5d5a0d322f6af6 531 Pfam PF13193 AMP-binding enzyme C-terminal domain 441 518 5.7E-20 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain DFR85_14620 eaeea8139068ec332b5d5a0d322f6af6 531 ProSitePatterns PS00455 Putative AMP-binding domain signature. 170 181 - T 31-10-2018 IPR020845 AMP-binding, conserved site DFR85_14620 eaeea8139068ec332b5d5a0d322f6af6 531 Gene3D G3DSA:3.30.300.310 427 531 4.6E-30 T 31-10-2018 DFR85_14620 eaeea8139068ec332b5d5a0d322f6af6 531 Gene3D G3DSA:3.40.50.12780 2 426 1.6E-109 T 31-10-2018 DFR85_14620 eaeea8139068ec332b5d5a0d322f6af6 531 Pfam PF00501 AMP-binding enzyme 20 431 7.4E-90 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 DFR85_02060 3dfcd1ee94838acca444686c1cdeb9d4 377 SUPERFAMILY SSF56762 55 372 1.26E-49 T 31-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_02060 3dfcd1ee94838acca444686c1cdeb9d4 377 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 201 303 1.9E-20 T 31-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_02060 3dfcd1ee94838acca444686c1cdeb9d4 377 Gene3D G3DSA:1.10.645.20 40 373 5.0E-52 T 31-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_02940 1747c106cd0b6bfdc679067bda8bf7f4 396 Gene3D G3DSA:1.20.1250.20 144 386 7.2E-9 T 31-10-2018 DFR85_02940 1747c106cd0b6bfdc679067bda8bf7f4 396 SUPERFAMILY SSF103473 17 390 1.16E-12 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_10440 57f4e4eacd7af3484445f4bd798fe863 456 Pfam PF02347 Glycine cleavage system P-protein 14 437 1.2E-107 T 31-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 DFR85_10440 57f4e4eacd7af3484445f4bd798fe863 456 Gene3D G3DSA:3.40.640.10 85 354 1.3E-141 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR85_10440 57f4e4eacd7af3484445f4bd798fe863 456 Gene3D G3DSA:3.90.1150.10 74 442 1.3E-141 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 DFR85_10440 57f4e4eacd7af3484445f4bd798fe863 456 SUPERFAMILY SSF53383 9 446 1.04E-96 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase DFR85_10440 57f4e4eacd7af3484445f4bd798fe863 456 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 4 446 45.891 T 31-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 DFR85_01665 7046347cc3a985d40b694181c13700ae 644 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 617 628 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR85_01665 7046347cc3a985d40b694181c13700ae 644 SUPERFAMILY SSF54862 541 635 1.34E-10 T 31-10-2018 DFR85_01665 7046347cc3a985d40b694181c13700ae 644 Gene3D G3DSA:3.30.70.20 568 643 7.8E-8 T 31-10-2018 DFR85_08525 a03b289090a16410442918f36e3a5780 288 Pfam PF03061 Thioesterase superfamily 157 235 1.1E-10 T 31-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 DFR85_08525 a03b289090a16410442918f36e3a5780 288 Pfam PF03061 Thioesterase superfamily 1 76 2.5E-7 T 31-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 DFR85_08525 a03b289090a16410442918f36e3a5780 288 SUPERFAMILY SSF54637 1 121 6.43E-23 T 31-10-2018 IPR029069 HotDog domain superfamily DFR85_08525 a03b289090a16410442918f36e3a5780 288 SUPERFAMILY SSF54637 140 279 3.06E-28 T 31-10-2018 IPR029069 HotDog domain superfamily DFR85_08525 a03b289090a16410442918f36e3a5780 288 Gene3D G3DSA:3.10.129.10 125 287 1.2E-32 T 31-10-2018 DFR85_08525 a03b289090a16410442918f36e3a5780 288 Gene3D G3DSA:3.10.129.10 1 124 3.5E-25 T 31-10-2018 DFR85_08340 cc10d3de6447ed0000ed4eadad08ff67 75 SUPERFAMILY SSF46785 2 72 1.39E-5 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_00930 ee50985d3ad2ec75e010ea241167f034 281 PRINTS PR00990 Ribokinase signature 7 28 3.5E-7 T 31-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 DFR85_00930 ee50985d3ad2ec75e010ea241167f034 281 PRINTS PR00990 Ribokinase signature 34 53 3.5E-7 T 31-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 DFR85_00930 ee50985d3ad2ec75e010ea241167f034 281 PRINTS PR00990 Ribokinase signature 187 198 3.5E-7 T 31-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 DFR85_00930 ee50985d3ad2ec75e010ea241167f034 281 Pfam PF00294 pfkB family carbohydrate kinase 7 261 5.1E-27 T 31-10-2018 IPR011611 Carbohydrate kinase PfkB DFR85_00930 ee50985d3ad2ec75e010ea241167f034 281 SUPERFAMILY SSF53613 6 267 1.56E-45 T 31-10-2018 IPR029056 Ribokinase-like DFR85_00930 ee50985d3ad2ec75e010ea241167f034 281 Gene3D G3DSA:3.40.1190.20 3 276 7.1E-50 T 31-10-2018 IPR029056 Ribokinase-like DFR85_03595 686f66f3f5bdda28ae51de83b0424ecd 334 SUPERFAMILY SSF53218 168 281 5.1E-22 T 31-10-2018 IPR036425 MoaB/Mog-like domain superfamily DFR85_03595 686f66f3f5bdda28ae51de83b0424ecd 334 Gene3D G3DSA:3.40.980.10 149 285 6.3E-19 T 31-10-2018 IPR036425 MoaB/Mog-like domain superfamily DFR85_03595 686f66f3f5bdda28ae51de83b0424ecd 334 SMART SM00852 171 284 1.1E-7 T 31-10-2018 IPR001453 MoaB/Mog domain DFR85_03595 686f66f3f5bdda28ae51de83b0424ecd 334 Pfam PF00994 Probable molybdopterin binding domain 171 273 3.6E-15 T 31-10-2018 IPR001453 MoaB/Mog domain DFR85_03470 cfd9267840ab03b0a92c38857c7d97f6 286 Pfam PF01040 UbiA prenyltransferase family 22 248 4.7E-20 T 31-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 DFR85_03470 cfd9267840ab03b0a92c38857c7d97f6 286 PIRSF PIRSF005355 2 286 1.7E-39 T 31-10-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 DFR85_01815 82445eb72e0b860c438156033eb577fc 252 SUPERFAMILY SSF52096 3 249 2.9E-51 T 31-10-2018 IPR029045 ClpP/crotonase-like domain superfamily DFR85_01815 82445eb72e0b860c438156033eb577fc 252 Pfam PF00378 Enoyl-CoA hydratase/isomerase 8 248 1.4E-36 T 31-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 DFR85_01815 82445eb72e0b860c438156033eb577fc 252 Gene3D G3DSA:3.90.226.10 1 247 1.6E-51 T 31-10-2018 DFR85_09060 24b5a1f05cdd164eb76b139f70d3fef2 162 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 4 129 5.9E-30 T 31-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 DFR85_09060 24b5a1f05cdd164eb76b139f70d3fef2 162 Gene3D G3DSA:3.40.50.300 1 151 3.2E-27 T 31-10-2018 DFR85_09060 24b5a1f05cdd164eb76b139f70d3fef2 162 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 4 108 3.9E-21 T 31-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 DFR85_09060 24b5a1f05cdd164eb76b139f70d3fef2 162 SUPERFAMILY SSF52540 3 107 5.31E-10 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_05970 e3fcae264118e69489679d0212f34539 155 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 9 151 2.5E-29 T 31-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 DFR85_05970 e3fcae264118e69489679d0212f34539 155 Pfam PF00692 dUTPase 60 145 2.0E-15 T 31-10-2018 IPR029054 dUTPase-like DFR85_05970 e3fcae264118e69489679d0212f34539 155 SUPERFAMILY SSF51283 2 152 2.49E-30 T 31-10-2018 IPR036157 dUTPase-like superfamily DFR85_05970 e3fcae264118e69489679d0212f34539 155 Gene3D G3DSA:2.70.40.10 1 137 1.7E-34 T 31-10-2018 IPR036157 dUTPase-like superfamily DFR85_01265 2de5cfd073c33ab9249f506ec7dba15a 265 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 14 260 2.8E-29 T 31-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 DFR85_01265 2de5cfd073c33ab9249f506ec7dba15a 265 SUPERFAMILY SSF161111 10 182 3.66E-11 T 31-10-2018 IPR027469 Cation efflux transmembrane domain superfamily DFR85_01265 2de5cfd073c33ab9249f506ec7dba15a 265 SUPERFAMILY SSF160240 200 257 3.92E-8 T 31-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 DFR85_01265 2de5cfd073c33ab9249f506ec7dba15a 265 Pfam PF01545 Cation efflux family 5 181 7.7E-11 T 31-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 DFR85_01265 2de5cfd073c33ab9249f506ec7dba15a 265 Gene3D G3DSA:1.20.1510.10 3 181 2.2E-5 T 31-10-2018 IPR027469 Cation efflux transmembrane domain superfamily DFR85_15715 9da0ada246851d7bebd79b1c588c90d3 78 SUPERFAMILY SSF46785 4 72 1.05E-11 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_15715 9da0ada246851d7bebd79b1c588c90d3 78 Gene3D G3DSA:1.10.10.10 3 76 8.8E-8 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_07980 1bdc2748975e8d40faec962a3e885a4a 108 Pfam PF03297 S25 ribosomal protein 14 106 4.1E-17 T 31-10-2018 IPR004977 Ribosomal protein S25 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07980 1bdc2748975e8d40faec962a3e885a4a 108 SUPERFAMILY SSF46785 53 106 2.47E-5 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_07980 1bdc2748975e8d40faec962a3e885a4a 108 ProDom PD012268 RIBOSOMAL S25 40S RIBONUCLEOPROTEIN S25 MULTIGENE FAMILY TRANSCRIPTION STRAIN DIRECT 57 108 0.009 T 31-10-2018 IPR004977 Ribosomal protein S25 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_07980 1bdc2748975e8d40faec962a3e885a4a 108 Gene3D G3DSA:1.10.10.10 37 108 3.2E-11 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_14850 4924c0d15720240d74b1f0bae7f57715 148 Pfam PF13380 CoA binding domain 16 135 1.2E-37 T 31-10-2018 IPR003781 CoA-binding GO:0048037 DFR85_14850 4924c0d15720240d74b1f0bae7f57715 148 Gene3D G3DSA:3.40.50.720 1 142 2.3E-41 T 31-10-2018 DFR85_14850 4924c0d15720240d74b1f0bae7f57715 148 SUPERFAMILY SSF51735 7 136 1.13E-37 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_14850 4924c0d15720240d74b1f0bae7f57715 148 SMART SM00881 12 109 1.4E-23 T 31-10-2018 IPR003781 CoA-binding GO:0048037 DFR85_15280 ca61a71d526d6498dde7cb0d5865ed2e 192 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 12 180 2.7E-33 T 31-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 DFR85_15280 ca61a71d526d6498dde7cb0d5865ed2e 192 Gene3D G3DSA:3.40.920.10 1 189 6.1E-39 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 DFR85_15280 ca61a71d526d6498dde7cb0d5865ed2e 192 SUPERFAMILY SSF53323 4 185 1.44E-28 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 DFR85_07910 7aafd39877036b0c49ba1bef673c5cb5 336 Hamap MF_00288 Methionine synthase [metE]. 7 320 44.211 T 31-10-2018 IPR022921 Methionine synthase MetE, archaeal GO:0008168|GO:0009086 DFR85_07910 7aafd39877036b0c49ba1bef673c5cb5 336 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 7 316 2.7E-59 T 31-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 DFR85_07910 7aafd39877036b0c49ba1bef673c5cb5 336 Gene3D G3DSA:3.20.20.210 1 327 1.1E-111 T 31-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 DFR85_07910 7aafd39877036b0c49ba1bef673c5cb5 336 SUPERFAMILY SSF51726 9 326 3.4E-84 T 31-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 DFR85_05940 901297e00eb7c20069da482c138693cf 409 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 238 409 1.8E-14 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 DFR85_14910 1ae32ab6fb391b466fd788a9d012e777 820 SUPERFAMILY SSF51645 9 668 3.66E-97 T 31-10-2018 IPR011076 Malate synthase-like superfamily GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 DFR85_14910 1ae32ab6fb391b466fd788a9d012e777 820 Gene3D G3DSA:3.20.20.360 82 460 3.4E-82 T 31-10-2018 DFR85_14910 1ae32ab6fb391b466fd788a9d012e777 820 Pfam PF01274 Malate synthase 33 370 3.1E-40 T 31-10-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 DFR85_00780 2a73e133a5a8e94632eb16ebd798f8dc 494 SUPERFAMILY SSF51717 189 357 4.51E-10 T 31-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 DFR85_00780 2a73e133a5a8e94632eb16ebd798f8dc 494 TIGRFAM TIGR00284 TIGR00284: dihydropteroate synthase-related protein 1 483 6.2E-158 T 31-10-2018 IPR005236 Dihydropteroate synthase-related protein synthase-related protein DFR85_08045 bd560c8760b8c79a871ebfcd58d2a52c 264 Gene3D G3DSA:3.50.50.60 6 264 8.6E-95 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_08045 bd560c8760b8c79a871ebfcd58d2a52c 264 SUPERFAMILY SSF51905 7 261 6.48E-44 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_08045 bd560c8760b8c79a871ebfcd58d2a52c 264 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 34 53 2.4E-7 T 31-10-2018 DFR85_08045 bd560c8760b8c79a871ebfcd58d2a52c 264 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 169 187 2.4E-7 T 31-10-2018 DFR85_08045 bd560c8760b8c79a871ebfcd58d2a52c 264 TIGRFAM TIGR00292 TIGR00292: thiazole biosynthesis enzyme 11 261 9.2E-101 T 31-10-2018 IPR002922 Thiazole biosynthetic enzyme Thi4 family DFR85_08045 bd560c8760b8c79a871ebfcd58d2a52c 264 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 33 55 6.3E-6 T 31-10-2018 DFR85_08045 bd560c8760b8c79a871ebfcd58d2a52c 264 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 172 181 6.3E-6 T 31-10-2018 DFR85_08045 bd560c8760b8c79a871ebfcd58d2a52c 264 Pfam PF01946 Thi4 family 15 243 5.6E-79 T 31-10-2018 DFR85_08045 bd560c8760b8c79a871ebfcd58d2a52c 264 Hamap MF_00304 Thiamine thiazole synthase [thi4]. 9 262 41.858 T 31-10-2018 IPR022828 Thiazole biosynthetic enzyme, prokaryotic DFR85_08375 7ce8c063d35224b307947ce033f7129c 279 Pfam PF07849 Protein of unknown function (DUF1641) 238 273 5.9E-15 T 31-10-2018 IPR012440 Protein of unknown function DUF1641 DFR85_15010 89ca10d077189e4c148c83ec933db7f9 222 Pfam PF04967 HTH DNA binding domain 168 219 7.6E-17 T 31-10-2018 IPR007050 Bacterioopsin activator-type, HTH domain DFR85_09620 2a622d3d4bfb643937408bbc74b6eab6 311 Hamap MF_00701 DNA primase large subunit PriL [priL]. 7 309 24.038 T 31-10-2018 IPR023642 DNA primase large subunit PriL GO:0003896 DFR85_09620 2a622d3d4bfb643937408bbc74b6eab6 311 SUPERFAMILY SSF140914 7 221 9.02E-38 T 31-10-2018 DFR85_06195 1e8c48e34184a165a12bdbd23c266c29 239 Pfam PF01935 Domain of unknown function DUF87 3 69 1.2E-14 T 31-10-2018 IPR002789 Helicase HerA, central domain DFR85_06195 1e8c48e34184a165a12bdbd23c266c29 239 SUPERFAMILY SSF52540 14 223 6.19E-23 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_06195 1e8c48e34184a165a12bdbd23c266c29 239 Gene3D G3DSA:3.40.50.300 1 239 1.5E-54 T 31-10-2018 DFR85_05780 13f20243ad08ae067aa96ab4aa5a3b6c 338 Gene3D G3DSA:1.10.287.70 27 117 1.1E-6 T 31-10-2018 DFR85_05780 13f20243ad08ae067aa96ab4aa5a3b6c 338 Pfam PF02254 TrkA-N domain 131 241 3.4E-16 T 31-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 DFR85_05780 13f20243ad08ae067aa96ab4aa5a3b6c 338 SUPERFAMILY SSF116726 291 337 6.41E-5 T 31-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 DFR85_05780 13f20243ad08ae067aa96ab4aa5a3b6c 338 SUPERFAMILY SSF51735 125 263 1.18E-24 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_05780 13f20243ad08ae067aa96ab4aa5a3b6c 338 Gene3D G3DSA:3.40.50.720 125 265 1.2E-25 T 31-10-2018 DFR85_05780 13f20243ad08ae067aa96ab4aa5a3b6c 338 SUPERFAMILY SSF81324 23 139 1.31E-7 T 31-10-2018 DFR85_00670 7f31eca33c4c999871b060f48e79330c 443 Gene3D G3DSA:3.40.225.10 258 443 6.2E-46 T 31-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily DFR85_00670 7f31eca33c4c999871b060f48e79330c 443 Gene3D G3DSA:3.40.1190.20 1 257 1.3E-69 T 31-10-2018 IPR029056 Ribokinase-like DFR85_00670 7f31eca33c4c999871b060f48e79330c 443 Pfam PF08543 Phosphomethylpyrimidine kinase 13 253 1.3E-73 T 31-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 DFR85_00670 7f31eca33c4c999871b060f48e79330c 443 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 6 254 2.1E-75 T 31-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 DFR85_00670 7f31eca33c4c999871b060f48e79330c 443 Pfam PF10120 Thiamine-phosphate synthase 270 434 6.3E-45 T 31-10-2018 IPR019293 Thiamine-phosphate synthase ThiN GO:0004789 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 DFR85_00670 7f31eca33c4c999871b060f48e79330c 443 SUPERFAMILY SSF53613 2 258 3.74E-59 T 31-10-2018 IPR029056 Ribokinase-like DFR85_00670 7f31eca33c4c999871b060f48e79330c 443 SUPERFAMILY SSF53639 262 438 2.16E-47 T 31-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily DFR85_04730 c43b09b26e074210e7d33236ef198cf1 129 Pfam PF01850 PIN domain 9 114 5.0E-7 T 31-10-2018 IPR002716 PIN domain DFR85_04730 c43b09b26e074210e7d33236ef198cf1 129 Gene3D G3DSA:3.40.50.1010 2 128 3.6E-26 T 31-10-2018 DFR85_04730 c43b09b26e074210e7d33236ef198cf1 129 SUPERFAMILY SSF88723 7 117 1.88E-15 T 31-10-2018 IPR029060 PIN-like domain superfamily DFR85_01210 502eee6ed4a69724899452153c127343 143 PIRSF PIRSF014422 1 143 2.2E-54 T 31-10-2018 IPR016618 Uncharacterised conserved protein UCP014422 DFR85_03855 1653fcb6af9bf5f05706eeb557c47e72 425 Gene3D G3DSA:3.40.50.300 17 354 6.8E-10 T 31-10-2018 DFR85_03855 1653fcb6af9bf5f05706eeb557c47e72 425 SUPERFAMILY SSF52540 35 347 2.59E-8 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_03855 1653fcb6af9bf5f05706eeb557c47e72 425 Pfam PF13175 AAA ATPase domain 21 346 8.2E-13 T 31-10-2018 DFR85_04360 00e7c707c99c957d8c5182b095ba988d 355 SUPERFAMILY SSF53756 41 349 2.51E-33 T 31-10-2018 DFR85_04360 00e7c707c99c957d8c5182b095ba988d 355 Pfam PF00534 Glycosyl transferases group 1 170 332 5.6E-22 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 DFR85_04360 00e7c707c99c957d8c5182b095ba988d 355 Gene3D G3DSA:3.40.50.2000 166 336 2.2E-29 T 31-10-2018 DFR85_07510 eea25d595f870505fd3ee33d3f16fb02 426 Pfam PF00589 Phage integrase family 227 392 1.5E-13 T 31-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 DFR85_07510 eea25d595f870505fd3ee33d3f16fb02 426 SUPERFAMILY SSF56349 129 397 1.68E-22 T 31-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 DFR85_05610 86677ea4c988c7528e246463cab8e8c9 182 Gene3D G3DSA:3.40.190.200 1 180 1.4E-23 T 31-10-2018 DFR85_05610 86677ea4c988c7528e246463cab8e8c9 182 Pfam PF12916 Protein of unknown function (DUF3834) 2 157 3.1E-45 T 31-10-2018 IPR024533 Protein of unknown function DUF3834 DFR85_01530 fe78b12acef83ed1cf4045e7f721ce9c 269 Gene3D G3DSA:3.60.110.10 1 253 1.4E-67 T 31-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily DFR85_01530 fe78b12acef83ed1cf4045e7f721ce9c 269 Pfam PF00795 Carbon-nitrogen hydrolase 7 249 1.9E-27 T 31-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 DFR85_01530 fe78b12acef83ed1cf4045e7f721ce9c 269 SUPERFAMILY SSF56317 3 261 8.89E-56 T 31-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily DFR85_05950 a80502d5f2c0bc8d3130d2cb6a779907 132 SUPERFAMILY SSF55961 1 79 6.68E-7 T 31-10-2018 DFR85_05450 7cdb39563ad439488b1646b0456f2c32 267 Pfam PF04055 Radical SAM superfamily 28 182 4.9E-13 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR85_05450 7cdb39563ad439488b1646b0456f2c32 267 SMART SM00729 21 225 1.7E-28 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 DFR85_05450 7cdb39563ad439488b1646b0456f2c32 267 SUPERFAMILY SSF102114 26 255 1.24E-36 T 31-10-2018 DFR85_05450 7cdb39563ad439488b1646b0456f2c32 267 Gene3D G3DSA:3.20.20.70 14 228 2.5E-25 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_05560 f16f02011a682aae51b76605f9b7f938 331 Pfam PF12773 Double zinc ribbon 276 320 2.0E-12 T 31-10-2018 IPR025874 Double zinc ribbon DFR85_04820 623ec5592956fd61bee0f6bd840d779e 131 SUPERFAMILY SSF88723 1 124 4.49E-16 T 31-10-2018 IPR029060 PIN-like domain superfamily DFR85_04820 623ec5592956fd61bee0f6bd840d779e 131 Pfam PF01850 PIN domain 3 115 7.3E-17 T 31-10-2018 IPR002716 PIN domain DFR85_04820 623ec5592956fd61bee0f6bd840d779e 131 Gene3D G3DSA:3.40.50.1010 3 123 5.1E-10 T 31-10-2018 DFR85_05710 0c8fab1b46b8a66a20131cadef48013d 420 SUPERFAMILY SSF51905 1 398 3.89E-39 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_05710 0c8fab1b46b8a66a20131cadef48013d 420 Gene3D G3DSA:3.50.50.60 178 285 3.0E-18 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_05710 0c8fab1b46b8a66a20131cadef48013d 420 Gene3D G3DSA:3.50.50.60 1 59 4.8E-13 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_05710 0c8fab1b46b8a66a20131cadef48013d 420 PRINTS PR00419 Adrenodoxin reductase family signature 25 38 2.4E-6 T 31-10-2018 DFR85_05710 0c8fab1b46b8a66a20131cadef48013d 420 PRINTS PR00419 Adrenodoxin reductase family signature 2 24 2.4E-6 T 31-10-2018 DFR85_05710 0c8fab1b46b8a66a20131cadef48013d 420 Pfam PF01593 Flavin containing amine oxidoreductase 12 253 3.9E-13 T 31-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 DFR85_13985 b43c13def23a740ee9d9e7d24966ebc2 161 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 14 64 2.2E-4 T 31-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 DFR85_13985 b43c13def23a740ee9d9e7d24966ebc2 161 SUPERFAMILY SSF54292 9 87 1.62E-24 T 31-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 DFR85_13985 b43c13def23a740ee9d9e7d24966ebc2 161 Gene3D G3DSA:1.10.150.120 83 161 4.0E-34 T 31-10-2018 DFR85_13985 b43c13def23a740ee9d9e7d24966ebc2 161 Gene3D G3DSA:3.10.20.30 2 82 4.9E-31 T 31-10-2018 IPR012675 Beta-grasp domain superfamily DFR85_13985 b43c13def23a740ee9d9e7d24966ebc2 161 Pfam PF01799 [2Fe-2S] binding domain 81 153 6.3E-32 T 31-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 DFR85_13985 b43c13def23a740ee9d9e7d24966ebc2 161 SUPERFAMILY SSF47741 81 159 6.8E-34 T 31-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily DFR85_02895 7d0f646c3c228009c5e43fa6ca60bf28 228 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 13 180 4.3E-23 T 31-10-2018 IPR001248 Purine-cytosine permease GO:0016020|GO:0022857|GO:0055085 DFR85_02895 7d0f646c3c228009c5e43fa6ca60bf28 228 Gene3D G3DSA:1.10.4160.10 3 218 2.0E-37 T 31-10-2018 IPR038271 Purine-cytosine permease superfamily DFR85_01160 1507e82972bbf75c0f01f6fbb1f26245 129 Gene3D G3DSA:3.10.580.10 1 127 7.6E-34 T 31-10-2018 DFR85_01160 1507e82972bbf75c0f01f6fbb1f26245 129 SUPERFAMILY SSF54631 2 119 8.84E-31 T 31-10-2018 DFR85_01160 1507e82972bbf75c0f01f6fbb1f26245 129 Pfam PF00571 CBS domain 4 57 2.2E-11 T 31-10-2018 IPR000644 CBS domain DFR85_01160 1507e82972bbf75c0f01f6fbb1f26245 129 Pfam PF00571 CBS domain 66 119 4.2E-14 T 31-10-2018 IPR000644 CBS domain DFR85_01160 1507e82972bbf75c0f01f6fbb1f26245 129 SMART SM00116 10 57 3.7E-11 T 31-10-2018 IPR000644 CBS domain DFR85_01160 1507e82972bbf75c0f01f6fbb1f26245 129 SMART SM00116 73 120 5.3E-9 T 31-10-2018 IPR000644 CBS domain DFR85_02840 9dbba5a5c47ffe132fbf4df9f10c75b8 264 Gene3D G3DSA:3.60.110.10 1 263 8.0E-74 T 31-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily DFR85_02840 9dbba5a5c47ffe132fbf4df9f10c75b8 264 SUPERFAMILY SSF56317 1 262 1.44E-68 T 31-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily DFR85_02840 9dbba5a5c47ffe132fbf4df9f10c75b8 264 Pfam PF00795 Carbon-nitrogen hydrolase 3 248 1.4E-52 T 31-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 DFR85_00340 0a70038a5356f5fb4d7e4fdb98ca9855 126 SUPERFAMILY SSF49764 20 117 7.67E-17 T 31-10-2018 IPR008978 HSP20-like chaperone DFR85_00340 0a70038a5356f5fb4d7e4fdb98ca9855 126 Gene3D G3DSA:2.60.40.790 5 126 5.5E-29 T 31-10-2018 IPR008978 HSP20-like chaperone DFR85_00340 0a70038a5356f5fb4d7e4fdb98ca9855 126 Pfam PF00011 Hsp20/alpha crystallin family 35 118 6.9E-8 T 31-10-2018 IPR002068 Alpha crystallin/Hsp20 domain DFR85_13025 b04a6abd3c442fa0d49b23e418a0369c 155 SUPERFAMILY SSF48452 19 145 2.21E-8 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 DFR85_13025 b04a6abd3c442fa0d49b23e418a0369c 155 Pfam PF12688 Tetratrico peptide repeat 34 151 6.0E-18 T 31-10-2018 DFR85_13025 b04a6abd3c442fa0d49b23e418a0369c 155 Gene3D G3DSA:1.25.40.10 11 152 1.5E-8 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 DFR85_05000 beb74f9911c998d4e7d169b832a0b574 262 Gene3D G3DSA:3.90.550.10 2 189 1.1E-8 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_05000 beb74f9911c998d4e7d169b832a0b574 262 SUPERFAMILY SSF53448 3 194 1.37E-11 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_05000 beb74f9911c998d4e7d169b832a0b574 262 Pfam PF00535 Glycosyl transferase family 2 12 80 5.9E-7 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 DFR85_08630 df420d71473e6de610b56fb81f519e30 180 Pfam PF08241 Methyltransferase domain 40 125 1.4E-4 T 31-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 DFR85_08630 df420d71473e6de610b56fb81f519e30 180 SUPERFAMILY SSF53335 23 154 6.23E-18 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR85_08630 df420d71473e6de610b56fb81f519e30 180 Gene3D G3DSA:3.40.50.150 4 179 1.7E-32 T 31-10-2018 DFR85_03340 63e192d2551e4aad85d0f7b7e9f74a3a 754 Gene3D G3DSA:1.20.1640.10 214 401 9.7E-7 T 31-10-2018 DFR85_03340 63e192d2551e4aad85d0f7b7e9f74a3a 754 Pfam PF03176 MMPL family 462 749 2.9E-26 T 31-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 DFR85_03340 63e192d2551e4aad85d0f7b7e9f74a3a 754 Pfam PF03176 MMPL family 39 426 1.1E-37 T 31-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 DFR85_03340 63e192d2551e4aad85d0f7b7e9f74a3a 754 SUPERFAMILY SSF82866 544 751 9.42E-16 T 31-10-2018 DFR85_03340 63e192d2551e4aad85d0f7b7e9f74a3a 754 SUPERFAMILY SSF82866 221 403 1.44E-26 T 31-10-2018 DFR85_09295 54f5d8c6a38ca7046834026569ef68ab 112 SUPERFAMILY SSF50249 6 111 1.59E-27 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR85_09295 54f5d8c6a38ca7046834026569ef68ab 112 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 2 112 3.7E-38 T 31-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 DFR85_09295 54f5d8c6a38ca7046834026569ef68ab 112 Pfam PF01588 Putative tRNA binding domain 13 110 6.0E-27 T 31-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 DFR85_09295 54f5d8c6a38ca7046834026569ef68ab 112 Gene3D G3DSA:2.40.50.140 1 112 2.3E-34 T 31-10-2018 DFR85_11120 1b7df6f021fc317796c6df98bf74c6a8 120 Gene3D G3DSA:3.40.1260.10 1 119 1.3E-12 T 31-10-2018 IPR027396 DsrEFH-like DFR85_11120 1b7df6f021fc317796c6df98bf74c6a8 120 SUPERFAMILY SSF75169 5 119 3.36E-15 T 31-10-2018 IPR027396 DsrEFH-like DFR85_11120 1b7df6f021fc317796c6df98bf74c6a8 120 Pfam PF02635 DsrE/DsrF-like family 4 119 5.3E-13 T 31-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein DFR85_11625 85bacc70175d432509700cdd625d5fe7 208 Pfam PF16955 Ferrous iron uptake permease, iron-lead transporter 1 207 9.3E-97 T 31-10-2018 IPR031594 Putative iron/lead transporter DFR85_15090 a0479753165691f587a95ac8c412f236 422 Gene3D G3DSA:1.20.1250.20 224 420 5.7E-22 T 31-10-2018 DFR85_15090 a0479753165691f587a95ac8c412f236 422 Gene3D G3DSA:1.20.1250.20 3 212 4.7E-42 T 31-10-2018 DFR85_15090 a0479753165691f587a95ac8c412f236 422 SUPERFAMILY SSF103473 4 419 7.32E-74 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_15090 a0479753165691f587a95ac8c412f236 422 Pfam PF07690 Major Facilitator Superfamily 18 380 5.3E-41 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_05870 84ee99c4fe5d5f6158b0ec6fa3628d1d 67 Pfam PF01402 Ribbon-helix-helix protein, copG family 22 59 1.6E-10 T 31-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 DFR85_05870 84ee99c4fe5d5f6158b0ec6fa3628d1d 67 Gene3D G3DSA:1.10.1220.10 19 63 5.0E-10 T 31-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 DFR85_05870 84ee99c4fe5d5f6158b0ec6fa3628d1d 67 SUPERFAMILY SSF47598 18 62 4.0E-11 T 31-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 DFR85_00705 23a9f9913c904e2252abf4a42e00e45d 263 ProDom PD016827 ARCHAEA ST0532 APE1937 VNG0250C MM2281 PAE3406 AF0927 UNCHARACTERIZED C3_0043 MJ0209 78 259 1.0E-61 T 31-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase DFR85_00705 23a9f9913c904e2252abf4a42e00e45d 263 PIRSF PIRSF004853 13 263 3.1E-112 T 31-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase DFR85_00705 23a9f9913c904e2252abf4a42e00e45d 263 Pfam PF02006 Phosphopantothenate/pantothenate synthetase 78 250 5.7E-70 T 31-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase DFR85_00705 23a9f9913c904e2252abf4a42e00e45d 263 Gene3D G3DSA:3.40.50.12640 14 263 3.8E-102 T 31-10-2018 IPR038138 Phosphopantoate/pantothenate synthetase superfamily DFR85_12825 8745b180200e4c8d22141116cc68dfa0 1073 Pfam PF05317 Thermopsin 67 321 1.5E-77 T 31-10-2018 IPR007981 Peptidase A5, thermopsin DFR85_07245 b46abda586838d8cc340b12cceff4b05 208 Pfam PF04919 Protein of unknown function (DUF655) 9 181 1.2E-60 T 31-10-2018 IPR007003 Protein of unknown function DUF655 DFR85_07245 b46abda586838d8cc340b12cceff4b05 208 SUPERFAMILY SSF160975 9 181 6.93E-68 T 31-10-2018 DFR85_07245 b46abda586838d8cc340b12cceff4b05 208 Gene3D G3DSA:2.40.50.140 9 76 9.5E-15 T 31-10-2018 DFR85_07245 b46abda586838d8cc340b12cceff4b05 208 Gene3D G3DSA:1.10.150.280 77 173 2.2E-34 T 31-10-2018 DFR85_04370 32e3bac3540aea826088cf56236555ff 214 SUPERFAMILY SSF53335 17 169 7.07E-14 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR85_04370 32e3bac3540aea826088cf56236555ff 214 Gene3D G3DSA:3.40.50.150 5 158 5.3E-14 T 31-10-2018 DFR85_04370 32e3bac3540aea826088cf56236555ff 214 Pfam PF13489 Methyltransferase domain 18 115 5.0E-9 T 31-10-2018 DFR85_13130 2a7fd45b247f72b79391a8fdf83eef84 174 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 20 171 7.7E-19 T 31-10-2018 IPR013343 CRISPR-associated protein Cas4 DFR85_13130 2a7fd45b247f72b79391a8fdf83eef84 174 Gene3D G3DSA:3.90.320.10 9 172 1.7E-5 T 31-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal DFR85_13130 2a7fd45b247f72b79391a8fdf83eef84 174 Pfam PF01930 Domain of unknown function DUF83 18 171 3.7E-39 T 31-10-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 DFR85_10095 20df353f692ac0ae774d35a23660fa87 72 Gene3D G3DSA:3.30.110.40 6 72 7.2E-7 T 31-10-2018 IPR036868 TusA-like domain superfamily DFR85_10095 20df353f692ac0ae774d35a23660fa87 72 SUPERFAMILY SSF64307 9 68 4.58E-10 T 31-10-2018 IPR036868 TusA-like domain superfamily DFR85_10095 20df353f692ac0ae774d35a23660fa87 72 Pfam PF01206 Sulfurtransferase TusA 9 68 2.7E-7 T 31-10-2018 IPR001455 TusA-like domain DFR85_14890 ac9f6bd56dd200ab27d8f30dbf7109e9 232 TIGRFAM TIGR03462 CarR_dom_SF: lycopene cyclase domain 134 222 2.1E-16 T 31-10-2018 IPR017825 Lycopene cyclase domain GO:0016872 KEGG: 00906+2.5.1.32+5.5.1.19|MetaCyc: PWY-5943|MetaCyc: PWY-5947|MetaCyc: PWY-6279|MetaCyc: PWY-7591|MetaCyc: PWY-7938|MetaCyc: PWY-7939|MetaCyc: PWY-7947 DFR85_14890 ac9f6bd56dd200ab27d8f30dbf7109e9 232 TIGRFAM TIGR03462 CarR_dom_SF: lycopene cyclase domain 11 97 2.2E-19 T 31-10-2018 IPR017825 Lycopene cyclase domain GO:0016872 KEGG: 00906+2.5.1.32+5.5.1.19|MetaCyc: PWY-5943|MetaCyc: PWY-5947|MetaCyc: PWY-6279|MetaCyc: PWY-7591|MetaCyc: PWY-7938|MetaCyc: PWY-7939|MetaCyc: PWY-7947 DFR85_01635 b75ad2b37295bdcfaceee1743de3e66d 175 Gene3D G3DSA:3.40.1010.10 1 110 1.0E-26 T 31-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 DFR85_01635 b75ad2b37295bdcfaceee1743de3e66d 175 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 2 151 5.2E-31 T 31-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 DFR85_01635 b75ad2b37295bdcfaceee1743de3e66d 175 SUPERFAMILY SSF53790 2 145 4.58E-31 T 31-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 DFR85_14175 50c6e2554672d4d14d5ee559298c5a7d 175 Pfam PF02517 CAAX protease self-immunity 92 170 4.6E-14 T 31-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 DFR85_08820 6bad7c1754bb8e16af904c51ee204738 218 Pfam PF01909 Nucleotidyltransferase domain 35 63 4.7E-6 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 DFR85_08820 6bad7c1754bb8e16af904c51ee204738 218 Gene3D G3DSA:3.30.460.10 6 110 1.3E-7 T 31-10-2018 DFR85_08820 6bad7c1754bb8e16af904c51ee204738 218 PIRSF PIRSF005928 1 218 2.3E-78 T 31-10-2018 IPR009185 Predicted nucleotidyltransferase DFR85_08820 6bad7c1754bb8e16af904c51ee204738 218 SUPERFAMILY SSF81301 35 91 5.18E-9 T 31-10-2018 DFR85_12805 57c416769142c8ba15d138fde5e405b3 271 Gene3D G3DSA:2.70.70.10 6 117 2.0E-7 T 31-10-2018 IPR011055 Duplicated hybrid motif DFR85_09755 6abe8d639d5b00730c18795f52181345 72 Gene3D G3DSA:3.30.110.40 1 70 3.5E-5 T 31-10-2018 IPR036868 TusA-like domain superfamily DFR85_09755 6abe8d639d5b00730c18795f52181345 72 SUPERFAMILY SSF64307 1 70 1.07E-8 T 31-10-2018 IPR036868 TusA-like domain superfamily DFR85_03320 918b5017f40f022edff7ca218777be10 291 Pfam PF06675 Protein of unknown function (DUF1177) 46 288 6.3E-84 T 31-10-2018 IPR009561 Protein of unknown function DUF1177 DFR85_10375 bec05b8e9ba4ac4e167c704888a45164 362 SUPERFAMILY SSF103473 10 356 3.66E-10 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_02575 bfebb0cf6af8d56797d0ea57aadb9f36 577 SUPERFAMILY SSF69322 118 318 1.03E-12 T 31-10-2018 DFR85_02575 bfebb0cf6af8d56797d0ea57aadb9f36 577 Gene3D G3DSA:3.40.50.1820 336 577 8.7E-63 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold DFR85_02575 bfebb0cf6af8d56797d0ea57aadb9f36 577 SUPERFAMILY SSF53474 345 577 6.18E-54 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold DFR85_02575 bfebb0cf6af8d56797d0ea57aadb9f36 577 Pfam PF00326 Prolyl oligopeptidase family 368 577 5.7E-47 T 31-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 DFR85_08660 15b8b8d1eb27e72a9723fb977b813260 110 Gene3D G3DSA:3.40.140.10 1 100 5.7E-8 T 31-10-2018 DFR85_08660 15b8b8d1eb27e72a9723fb977b813260 110 SUPERFAMILY SSF102712 2 75 3.92E-10 T 31-10-2018 DFR85_02270 19013d1d1aa85ea26ab19332f51505f1 405 Pfam PF01566 Natural resistance-associated macrophage protein 42 382 7.5E-49 T 31-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 DFR85_09580 d8ed8ef2bf15ece12a4b86d7ff4c2210 53 Pfam PF08112 ATP synthase epsilon subunit 4 50 9.1E-11 T 31-10-2018 IPR012508 ATPase, A1 complex, epsilon subunit, archaeal GO:0015986|GO:0033178|GO:0042626 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 DFR85_00170 eb2abc14994eca92d8b2ae8c9febfff0 195 Gene3D G3DSA:1.20.1250.20 1 193 1.6E-36 T 31-10-2018 DFR85_00170 eb2abc14994eca92d8b2ae8c9febfff0 195 Pfam PF00083 Sugar (and other) transporter 1 189 1.1E-29 T 31-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 DFR85_00170 eb2abc14994eca92d8b2ae8c9febfff0 195 ProSitePatterns PS00216 Sugar transport proteins signature 1. 46 62 - T 31-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 DFR85_00170 eb2abc14994eca92d8b2ae8c9febfff0 195 SUPERFAMILY SSF103473 5 187 9.29E-19 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_11895 69d46d73deea75caf207d455d1586312 382 SUPERFAMILY SSF53300 39 197 3.27E-29 T 31-10-2018 IPR036465 von Willebrand factor A-like domain superfamily DFR85_11895 69d46d73deea75caf207d455d1586312 382 SMART SM00327 37 198 6.3E-17 T 31-10-2018 IPR002035 von Willebrand factor, type A DFR85_11895 69d46d73deea75caf207d455d1586312 382 Gene3D G3DSA:3.40.50.410 39 204 4.5E-33 T 31-10-2018 IPR036465 von Willebrand factor A-like domain superfamily DFR85_11895 69d46d73deea75caf207d455d1586312 382 Pfam PF00092 von Willebrand factor type A domain 41 193 1.2E-17 T 31-10-2018 IPR002035 von Willebrand factor, type A DFR85_12370 b290116ab7bd8f54e870cbd4f5f66e89 353 Pfam PF02371 Transposase IS116/IS110/IS902 family 232 317 1.3E-23 T 31-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 DFR85_12840 5f7844de0b03d3aee1e25cc3788f5fc7 368 Pfam PF00083 Sugar (and other) transporter 39 172 1.6E-12 T 31-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 DFR85_12840 5f7844de0b03d3aee1e25cc3788f5fc7 368 SUPERFAMILY SSF103473 6 365 3.27E-38 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_12840 5f7844de0b03d3aee1e25cc3788f5fc7 368 Gene3D G3DSA:1.20.1250.20 4 368 5.0E-37 T 31-10-2018 DFR85_15085 8cfcdbbd7c4ac59e7d041681f891f071 453 SUPERFAMILY SSF103473 26 437 1.96E-56 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_15085 8cfcdbbd7c4ac59e7d041681f891f071 453 Pfam PF07690 Major Facilitator Superfamily 31 390 3.5E-26 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_15085 8cfcdbbd7c4ac59e7d041681f891f071 453 Gene3D G3DSA:1.20.1250.20 24 453 1.8E-55 T 31-10-2018 DFR85_02655 80cc39e97d077c03f20cbe33bb23be19 323 SMART SM00382 45 240 1.7E-15 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_02655 80cc39e97d077c03f20cbe33bb23be19 323 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 296 1.5E-19 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 DFR85_02655 80cc39e97d077c03f20cbe33bb23be19 323 Pfam PF00005 ABC transporter 36 183 2.8E-34 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 DFR85_02655 80cc39e97d077c03f20cbe33bb23be19 323 Gene3D G3DSA:3.40.50.300 22 323 5.2E-94 T 31-10-2018 DFR85_02655 80cc39e97d077c03f20cbe33bb23be19 323 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 DFR85_02655 80cc39e97d077c03f20cbe33bb23be19 323 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 315 2.5E-25 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 DFR85_02655 80cc39e97d077c03f20cbe33bb23be19 323 SUPERFAMILY SSF52540 22 254 1.18E-71 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_04920 99733f7a5d0fff09c8d38e951682be98 459 Pfam PF13440 Polysaccharide biosynthesis protein 149 299 5.4E-9 T 31-10-2018 DFR85_13960 87d7b75293d904814d24604c0b1a7d93 361 TIGRFAM TIGR01765 tspaseT_teng_N: transposase, putative, N-terminal domain 20 90 2.2E-19 T 31-10-2018 IPR010094 Transposase (putative), N-terminal DFR85_02295 88248db9449e75583bfc3089d73083fd 477 SUPERFAMILY SSF161098 262 456 5.1E-21 T 31-10-2018 IPR035906 MetI-like superfamily DFR85_02295 88248db9449e75583bfc3089d73083fd 477 Gene3D G3DSA:1.10.3720.10 253 474 8.0E-19 T 31-10-2018 IPR035906 MetI-like superfamily DFR85_02295 88248db9449e75583bfc3089d73083fd 477 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 283 469 6.0E-21 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 DFR85_03480 8d98573e0f078df533f58216da3c39f4 389 Pfam PF01497 Periplasmic binding protein 121 319 2.4E-13 T 31-10-2018 IPR002491 ABC transporter periplasmic binding domain DFR85_03480 8d98573e0f078df533f58216da3c39f4 389 Gene3D G3DSA:3.40.50.1980 196 387 3.1E-49 T 31-10-2018 DFR85_03480 8d98573e0f078df533f58216da3c39f4 389 SUPERFAMILY SSF53807 50 348 1.18E-36 T 31-10-2018 DFR85_03480 8d98573e0f078df533f58216da3c39f4 389 Gene3D G3DSA:3.40.50.1980 43 194 2.0E-33 T 31-10-2018 DFR85_10790 7ee13f42a30da95edce12b699b2e2e97 319 SUPERFAMILY SSF58104 29 242 1.67E-5 T 31-10-2018 DFR85_12130 e22e134306f4436966f8e5b299cc408d 240 Pfam PF13240 zinc-ribbon domain 5 24 4.0E-6 T 31-10-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 DFR85_02190 8016e2ec79dbfb207ca6e8d5e3f4296d 104 PIRSF PIRSF000068 1 104 4.9E-42 T 31-10-2018 IPR009157 Ferredoxin zinc-binding GO:0008270|GO:0009055|GO:0051536 DFR85_02190 8016e2ec79dbfb207ca6e8d5e3f4296d 104 Pfam PF13187 4Fe-4S dicluster domain 46 99 6.3E-9 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR85_02190 8016e2ec79dbfb207ca6e8d5e3f4296d 104 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 84 95 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR85_02190 8016e2ec79dbfb207ca6e8d5e3f4296d 104 Gene3D G3DSA:3.30.70.20 2 104 1.1E-43 T 31-10-2018 DFR85_02190 8016e2ec79dbfb207ca6e8d5e3f4296d 104 SUPERFAMILY SSF54862 26 102 1.05E-19 T 31-10-2018 DFR85_14235 fe2b2c397886fe67ba46bbbcf256f19a 424 SUPERFAMILY SSF46548 38 141 2.96E-10 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 DFR85_14235 fe2b2c397886fe67ba46bbbcf256f19a 424 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 44 55 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site DFR85_14235 fe2b2c397886fe67ba46bbbcf256f19a 424 Pfam PF13183 4Fe-4S dicluster domain 42 121 2.8E-7 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR85_13890 2136f910ef299a51b1973560eb72693a 981 Pfam PF05317 Thermopsin 59 313 6.1E-70 T 31-10-2018 IPR007981 Peptidase A5, thermopsin DFR85_00935 51439fcaa0ccfe6eabf925f03580933c 447 Pfam PF06068 TIP49 C-terminus 15 406 2.2E-153 T 31-10-2018 IPR010339 TIP49, C-terminal GO:0003678|GO:0005524 Reactome: R-HSA-171319|Reactome: R-HSA-3214847 DFR85_00935 51439fcaa0ccfe6eabf925f03580933c 447 SUPERFAMILY SSF50249 125 207 1.27E-17 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR85_00935 51439fcaa0ccfe6eabf925f03580933c 447 SUPERFAMILY SSF52540 37 434 4.69E-38 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_00935 51439fcaa0ccfe6eabf925f03580933c 447 Gene3D G3DSA:3.40.50.300 18 352 5.5E-103 T 31-10-2018 DFR85_00935 51439fcaa0ccfe6eabf925f03580933c 447 Gene3D G3DSA:1.10.8.60 357 447 4.8E-30 T 31-10-2018 DFR85_00935 51439fcaa0ccfe6eabf925f03580933c 447 Gene3D G3DSA:2.40.50.360 119 245 5.5E-103 T 31-10-2018 DFR85_00935 51439fcaa0ccfe6eabf925f03580933c 447 SMART SM00382 62 356 7.9E-12 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_01810 e098fb03f3d8d24a443365d0a6fe4675 648 SUPERFAMILY SSF54862 546 634 5.72E-14 T 31-10-2018 DFR85_01810 e098fb03f3d8d24a443365d0a6fe4675 648 Gene3D G3DSA:3.30.70.20 565 639 7.9E-10 T 31-10-2018 DFR85_01810 e098fb03f3d8d24a443365d0a6fe4675 648 Pfam PF13237 4Fe-4S dicluster domain 573 624 3.4E-6 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR85_11480 37f1b8bdfabd08f75509e25c59e48d2a 286 ProDom PD022789 MEMBRANE SURFACE PRECURSOR SIGNAL PROTEIN YBJE TRANSMEMBRANE INNER PREDICTED STY0934 116 269 5.0E-49 T 31-10-2018 IPR005642 Lysine exporter LysO DFR85_11480 37f1b8bdfabd08f75509e25c59e48d2a 286 Pfam PF03956 Lysine exporter LysO 98 283 1.2E-42 T 31-10-2018 IPR005642 Lysine exporter LysO DFR85_02010 e2f5ec2bb493b40ebc4261c249997278 159 Pfam PF10061 Uncharacterized conserved protein (DUF2299) 6 142 5.3E-45 T 31-10-2018 IPR018747 Protein of unknown function DUF2299 DFR85_02010 e2f5ec2bb493b40ebc4261c249997278 159 Gene3D G3DSA:3.30.1460.10 3 147 7.6E-38 T 31-10-2018 DFR85_05765 cddade9663f3798378dbe1442b5f9e62 326 Gene3D G3DSA:1.10.3470.10 1 324 3.3E-72 T 31-10-2018 IPR037294 ABC transporter, BtuC-like DFR85_05765 cddade9663f3798378dbe1442b5f9e62 326 Pfam PF01032 FecCD transport family 11 319 8.5E-70 T 31-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 DFR85_05765 cddade9663f3798378dbe1442b5f9e62 326 SUPERFAMILY SSF81345 3 319 2.88E-61 T 31-10-2018 IPR037294 ABC transporter, BtuC-like DFR85_09725 5fc09b71b9f9397fd742ce9f7aab95bc 225 Pfam PF13938 Putative heavy-metal chelation 8 83 6.1E-13 T 31-10-2018 IPR025251 Domain of unknown function DUF4213 DFR85_09725 5fc09b71b9f9397fd742ce9f7aab95bc 225 Pfam PF04016 Putative heavy-metal chelation 96 218 5.1E-23 T 31-10-2018 IPR007161 Putative heavy-metal chelation domain DFR85_09725 5fc09b71b9f9397fd742ce9f7aab95bc 225 SUPERFAMILY SSF159713 1 219 4.05E-36 T 31-10-2018 DFR85_00500 ac6d14cca278b188a16fb5d95be9a9f9 1166 Gene3D G3DSA:1.20.1640.10 960 1164 3.3E-6 T 31-10-2018 DFR85_00500 ac6d14cca278b188a16fb5d95be9a9f9 1166 SUPERFAMILY SSF82866 977 1157 7.85E-22 T 31-10-2018 DFR85_00500 ac6d14cca278b188a16fb5d95be9a9f9 1166 Pfam PF03176 MMPL family 973 1157 1.4E-30 T 31-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 DFR85_00500 ac6d14cca278b188a16fb5d95be9a9f9 1166 Pfam PF03176 MMPL family 607 815 8.3E-33 T 31-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 DFR85_00500 ac6d14cca278b188a16fb5d95be9a9f9 1166 SUPERFAMILY SSF82866 616 806 4.05E-26 T 31-10-2018 DFR85_08725 08e6c5960dd8814e96e0e0ee3a35dbca 385 PIRSF PIRSF016495 9 385 1.4E-147 T 31-10-2018 IPR009995 Protein of unknown function DUF1512 DFR85_08725 08e6c5960dd8814e96e0e0ee3a35dbca 385 Pfam PF07431 Protein of unknown function (DUF1512) 30 384 1.8E-146 T 31-10-2018 IPR009995 Protein of unknown function DUF1512 DFR85_11490 324d0be490f611f454a0761be30cc83c 149 Pfam PF01909 Nucleotidyltransferase domain 19 85 1.7E-8 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 DFR85_11490 324d0be490f611f454a0761be30cc83c 149 SUPERFAMILY SSF81301 17 88 7.36E-11 T 31-10-2018 DFR85_11490 324d0be490f611f454a0761be30cc83c 149 Gene3D G3DSA:3.30.460.10 5 95 1.8E-11 T 31-10-2018 DFR85_15415 814773ea1bafdf12623aba62d2a83d7a 259 SUPERFAMILY SSF56529 22 256 5.1E-37 T 31-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 DFR85_15415 814773ea1bafdf12623aba62d2a83d7a 259 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 42 253 2.5E-41 T 31-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 DFR85_15415 814773ea1bafdf12623aba62d2a83d7a 259 Gene3D G3DSA:3.90.850.10 24 259 1.7E-41 T 31-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 DFR85_13735 9cf55db7cdf4b1ee4be9c72fac234071 167 SUPERFAMILY SSF46785 4 53 7.98E-5 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_11150 885e2cac904221f17ab6e588f0bb28ed 56 Hamap MF_00803 Ribosome biogenesis protein Nop10 [nop10]. 3 53 18.85 T 31-10-2018 IPR023532 H/ACA ribonucleoprotein complex subunit Nop10 , archaeal-type GO:0001522|GO:0030515|GO:0042254 DFR85_11150 885e2cac904221f17ab6e588f0bb28ed 56 Pfam PF04135 Nucleolar RNA-binding protein, Nop10p family 1 50 5.0E-25 T 31-10-2018 IPR007264 H/ACA ribonucleoprotein complex, subunit Nop10 GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 DFR85_11150 885e2cac904221f17ab6e588f0bb28ed 56 SUPERFAMILY SSF144210 1 53 4.84E-20 T 31-10-2018 IPR036756 H/ACA ribonucleoprotein complex, subunit Nop10 superfamily GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 DFR85_11150 885e2cac904221f17ab6e588f0bb28ed 56 Gene3D G3DSA:2.20.28.40 1 55 3.5E-25 T 31-10-2018 IPR036756 H/ACA ribonucleoprotein complex, subunit Nop10 superfamily GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 DFR85_08000 82c9b370980a0385f6975389bdb3226c 110 ProDom PD289296 ST0369 SSO0428 5 110 2.0E-14 T 31-10-2018 IPR020330 Uncharacterised protein family SSO0428 DFR85_08070 1664fc198c1682a7ac03f280a8ddbacf 210 SUPERFAMILY SSF109755 32 208 5.36E-6 T 31-10-2018 DFR85_08070 1664fc198c1682a7ac03f280a8ddbacf 210 Pfam PF01865 Protein of unknown function DUF47 106 205 3.0E-6 T 31-10-2018 IPR018445 Putative phosphate transport regulator DFR85_08070 1664fc198c1682a7ac03f280a8ddbacf 210 Gene3D G3DSA:1.20.58.220 10 206 3.2E-12 T 31-10-2018 IPR038078 PhoU-like domain superfamily DFR85_01240 6e6ee24246f5722ec00cdc2e6a27eb22 300 Pfam PF01609 Transposase DDE domain 107 280 1.6E-13 T 31-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 DFR85_10905 8c7424f5327e03fb0943cade5da8e2fc 311 Gene3D G3DSA:3.40.910.10 1 311 3.7E-91 T 31-10-2018 IPR036982 Deoxyhypusine synthase superfamily GO:0008612 Reactome: R-HSA-204626 DFR85_10905 8c7424f5327e03fb0943cade5da8e2fc 311 Pfam PF01916 Deoxyhypusine synthase 26 307 6.2E-99 T 31-10-2018 IPR002773 Deoxyhypusine synthase GO:0008612 Reactome: R-HSA-204626 DFR85_10905 8c7424f5327e03fb0943cade5da8e2fc 311 SUPERFAMILY SSF52467 3 310 2.26E-96 T 31-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily DFR85_10905 8c7424f5327e03fb0943cade5da8e2fc 311 Hamap MF_00153 Probable deoxyhypusine synthase [dys]. 22 310 41.365 T 31-10-2018 IPR022899 Deoxyhypusine synthase, putative, archaeal GO:0034038 DFR85_08515 1c66c3920a350bdf3e872caa2eb8fe6d 605 Gene3D G3DSA:3.40.50.300 399 595 9.9E-22 T 31-10-2018 DFR85_08515 1c66c3920a350bdf3e872caa2eb8fe6d 605 SMART SM00382 188 544 1.3E-4 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_08515 1c66c3920a350bdf3e872caa2eb8fe6d 605 Gene3D G3DSA:3.40.50.300 155 302 1.5E-13 T 31-10-2018 DFR85_08515 1c66c3920a350bdf3e872caa2eb8fe6d 605 SUPERFAMILY SSF52540 141 599 2.67E-34 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_08515 1c66c3920a350bdf3e872caa2eb8fe6d 605 Pfam PF01935 Domain of unknown function DUF87 168 461 1.3E-15 T 31-10-2018 IPR002789 Helicase HerA, central domain DFR85_07540 002e9fe5ad33f54ce02f03a84efbd692 57 Pfam PF03911 Sec61beta family 15 54 2.2E-18 T 31-10-2018 IPR016482 Protein transport protein SecG/Sec61-beta/Sbh Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 DFR85_07540 002e9fe5ad33f54ce02f03a84efbd692 57 Hamap MF_00751 Preprotein translocase subunit SecG [secG]. 3 55 15.909 T 31-10-2018 IPR023531 Preprotein translocase subunit SecG DFR85_11810 1cbbdb87021bedea8fc8342aacf5ace3 119 Pfam PF01986 Domain of unknown function DUF123 24 106 9.4E-16 T 31-10-2018 IPR002837 Protein of unknown function DUF123 DFR85_14920 9d025dba69c5a913e7fd344320444408 213 Pfam PF00324 Amino acid permease 20 186 3.4E-13 T 31-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 DFR85_14920 9d025dba69c5a913e7fd344320444408 213 Gene3D G3DSA:1.20.1740.10 7 211 1.3E-11 T 31-10-2018 DFR85_05670 884ac04aa6958871f461e0e0e98a0e0c 445 Gene3D G3DSA:1.20.1740.10 10 444 2.9E-35 T 31-10-2018 DFR85_05670 884ac04aa6958871f461e0e0e98a0e0c 445 Pfam PF00324 Amino acid permease 22 401 4.5E-23 T 31-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 DFR85_05670 884ac04aa6958871f461e0e0e98a0e0c 445 PIRSF PIRSF006060 1 445 1.9E-56 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_14225 ad19b110df7a21403d7eb7e6609b3680 745 SUPERFAMILY SSF56762 16 439 2.88E-20 T 31-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_14225 ad19b110df7a21403d7eb7e6609b3680 745 SUPERFAMILY SSF56762 538 711 4.71E-7 T 31-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_14225 ad19b110df7a21403d7eb7e6609b3680 745 ProSitePatterns PS00507 Nickel-dependent hydrogenases large subunit signature 1. 52 77 - T 31-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 DFR85_14225 ad19b110df7a21403d7eb7e6609b3680 745 Gene3D G3DSA:1.10.645.10 15 711 4.1E-126 T 31-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_06525 85aa8a4dff2b75f1b5e7ba471542243f 304 SUPERFAMILY SSF51735 4 298 7.93E-61 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_06525 85aa8a4dff2b75f1b5e7ba471542243f 304 Gene3D G3DSA:3.40.50.720 4 227 2.8E-75 T 31-10-2018 DFR85_06525 85aa8a4dff2b75f1b5e7ba471542243f 304 Gene3D G3DSA:3.90.25.10 166 288 2.8E-75 T 31-10-2018 DFR85_06525 85aa8a4dff2b75f1b5e7ba471542243f 304 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 227 2.1E-41 T 31-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 DFR85_06840 789eea1592d20b9627a35ef874f0c66d 137 PIRSF PIRSF008210 1 137 3.7E-61 T 31-10-2018 IPR014450 Uncharacterised conserved protein UCP008210 DFR85_06840 789eea1592d20b9627a35ef874f0c66d 137 Pfam PF09921 Uncharacterized protein conserved in archaea (DUF2153) 8 128 1.0E-55 T 31-10-2018 IPR014450 Uncharacterised conserved protein UCP008210 DFR85_08185 056b3eef7636cc4b13c9d92451aadc09 186 Pfam PF01810 LysE type translocator 13 180 1.3E-12 T 31-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 DFR85_03670 89603f53dfb31a5c38241293589945a3 467 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 22 456 4.6E-164 T 31-10-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 DFR85_03670 89603f53dfb31a5c38241293589945a3 467 Pfam PF01458 Uncharacterized protein family (UPF0051) 210 436 3.5E-59 T 31-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 DFR85_03670 89603f53dfb31a5c38241293589945a3 467 SUPERFAMILY SSF101960 34 461 8.24E-109 T 31-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily DFR85_03755 fab212c7fc5200212f5500264830e2d4 96 Gene3D G3DSA:3.30.70.100 6 94 5.6E-17 T 31-10-2018 DFR85_03755 fab212c7fc5200212f5500264830e2d4 96 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 74 2.8E-15 T 31-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain DFR85_03755 fab212c7fc5200212f5500264830e2d4 96 SUPERFAMILY SSF54909 1 94 2.75E-26 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel DFR85_15665 e28601e14d9fae342a63036108f01bd3 445 Gene3D G3DSA:1.20.1250.20 12 441 3.2E-24 T 31-10-2018 DFR85_15665 e28601e14d9fae342a63036108f01bd3 445 SUPERFAMILY SSF103473 8 433 9.55E-30 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_15665 e28601e14d9fae342a63036108f01bd3 445 Pfam PF07690 Major Facilitator Superfamily 20 386 2.2E-12 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_01395 7a381d030ef7f559781b4a6bef6f99ec 301 SUPERFAMILY SSF53335 68 273 2.05E-39 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR85_01395 7a381d030ef7f559781b4a6bef6f99ec 301 Gene3D G3DSA:3.30.300.110 53 127 1.5E-9 T 31-10-2018 DFR85_01395 7a381d030ef7f559781b4a6bef6f99ec 301 Pfam PF02475 Met-10+ like-protein 69 257 2.5E-34 T 31-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 DFR85_01395 7a381d030ef7f559781b4a6bef6f99ec 301 Gene3D G3DSA:3.40.50.150 128 296 2.6E-26 T 31-10-2018 DFR85_09205 bd681530f53853f37d081799c01a359d 179 SMART SM00835 69 177 0.0046 T 31-10-2018 IPR006045 Cupin 1 GO:0045735 DFR85_09205 bd681530f53853f37d081799c01a359d 179 Gene3D G3DSA:2.60.120.10 38 179 1.6E-35 T 31-10-2018 IPR014710 RmlC-like jelly roll fold DFR85_09205 bd681530f53853f37d081799c01a359d 179 Pfam PF07883 Cupin domain 95 162 2.0E-14 T 31-10-2018 IPR013096 Cupin 2, conserved barrel DFR85_09205 bd681530f53853f37d081799c01a359d 179 SUPERFAMILY SSF51182 40 174 5.46E-31 T 31-10-2018 IPR011051 RmlC-like cupin domain superfamily DFR85_07685 a670cb4da512034d94852521c136e525 172 Gene3D G3DSA:3.60.15.10 1 165 2.9E-8 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR85_07685 a670cb4da512034d94852521c136e525 172 SUPERFAMILY SSF56281 5 156 2.9E-10 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR85_07690 162b7520012e657a25370b734c29e7cd 237 SUPERFAMILY SSF53271 84 226 3.15E-26 T 31-10-2018 IPR029057 Phosphoribosyltransferase-like DFR85_07690 162b7520012e657a25370b734c29e7cd 237 Pfam PF00156 Phosphoribosyl transferase domain 113 222 4.4E-12 T 31-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 DFR85_07690 162b7520012e657a25370b734c29e7cd 237 Gene3D G3DSA:3.40.50.2020 61 236 8.9E-33 T 31-10-2018 DFR85_07420 a69e79eb52e09fcf224370246bf6ea7c 172 SUPERFAMILY SSF57783 1 40 1.19E-10 T 31-10-2018 DFR85_07420 a69e79eb52e09fcf224370246bf6ea7c 172 Gene3D G3DSA:2.20.25.10 1 38 3.7E-11 T 31-10-2018 DFR85_07420 a69e79eb52e09fcf224370246bf6ea7c 172 Pfam PF08271 TFIIB zinc-binding 1 39 1.7E-10 T 31-10-2018 IPR013137 Zinc finger, TFIIB-type DFR85_02560 e2072049ee3f3df0257d11ed47974197 101 Pfam PF01022 Bacterial regulatory protein, arsR family 19 63 3.6E-10 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DFR85_02560 e2072049ee3f3df0257d11ed47974197 101 SUPERFAMILY SSF46785 2 85 7.1E-16 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_02560 e2072049ee3f3df0257d11ed47974197 101 SMART SM00418 11 93 2.7E-8 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DFR85_02560 e2072049ee3f3df0257d11ed47974197 101 Gene3D G3DSA:1.10.10.10 7 97 2.7E-15 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_00345 4c50f9e7ce9331d8fd1a5658eca00b03 486 Pfam PF03109 ABC1 family 101 215 2.8E-27 T 31-10-2018 IPR004147 UbiB domain DFR85_00345 4c50f9e7ce9331d8fd1a5658eca00b03 486 SUPERFAMILY SSF56112 81 314 1.48E-25 T 31-10-2018 IPR011009 Protein kinase-like domain superfamily DFR85_00345 4c50f9e7ce9331d8fd1a5658eca00b03 486 Gene3D G3DSA:1.10.510.10 224 336 3.9E-5 T 31-10-2018 DFR85_02645 0fc453f5673016367e72e70c2d520fb2 356 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 171 355 7.2E-25 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 DFR85_02645 0fc453f5673016367e72e70c2d520fb2 356 Gene3D G3DSA:1.10.3720.10 143 350 1.1E-18 T 31-10-2018 IPR035906 MetI-like superfamily DFR85_02645 0fc453f5673016367e72e70c2d520fb2 356 SUPERFAMILY SSF161098 159 337 4.58E-21 T 31-10-2018 IPR035906 MetI-like superfamily DFR85_03690 0ec1f0eae0e95f55ded38e47721a0e00 251 Pfam PF01925 Sulfite exporter TauE/SafE 10 245 1.3E-33 T 31-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 DFR85_00360 936e3344342e51aa91ec962fe70a0a17 182 Pfam PF04173 TQO small subunit DoxD 17 182 1.1E-69 T 31-10-2018 IPR007301 TQO small subunit DoxD KEGG: 00920+1.8.5.2|MetaCyc: PWY-5303 DFR85_15325 7092744447389c81f5ece496436f89bf 272 Pfam PF07788 PD-(D/E)XK nuclease superfamily 194 267 4.4E-33 T 31-10-2018 IPR012431 PD-(D/E)XK nuclease DFR85_15325 7092744447389c81f5ece496436f89bf 272 Pfam PF12644 Protein of unknown function (DUF3782) 124 193 1.2E-21 T 31-10-2018 IPR024271 Protein of unknown function DUF3782 DFR85_15325 7092744447389c81f5ece496436f89bf 272 SUPERFAMILY SSF52980 90 272 1.98E-5 T 31-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 DFR85_04310 166f8dfc2bc41c89a09c7a896d9122f4 503 Pfam PF01943 Polysaccharide biosynthesis protein 14 287 2.9E-19 T 31-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 DFR85_15600 d0e2f1cc150ccc26931e4510773d9ad5 119 SUPERFAMILY SSF46785 4 87 6.18E-11 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_15600 d0e2f1cc150ccc26931e4510773d9ad5 119 Gene3D G3DSA:1.10.10.10 2 63 1.6E-7 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_10110 44f317d4731a79058880d35ef6f182f7 349 SUPERFAMILY SSF109755 128 289 2.49E-11 T 31-10-2018 DFR85_10110 44f317d4731a79058880d35ef6f182f7 349 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 12 50 1.2E-7 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR85_10110 44f317d4731a79058880d35ef6f182f7 349 Pfam PF01895 PhoU domain 142 230 1.2E-4 T 31-10-2018 IPR026022 PhoU domain DFR85_10110 44f317d4731a79058880d35ef6f182f7 349 SMART SM00966 8 54 1.7E-6 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 DFR85_09390 a87ddcc6a17e66976f269b8fd458eabd 199 Pfam PF01914 MarC family integral membrane protein 8 197 2.8E-29 T 31-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 DFR85_14270 9425c07da62878c486b80c72d893e978 74 Pfam PF07362 Post-segregation antitoxin CcdA 5 53 4.6E-7 T 31-10-2018 IPR009956 Post-segregation antitoxin CcdA DFR85_09535 fc9e652b49050b9d475649f854367ab5 126 Pfam PF13710 ACT domain 15 75 2.5E-10 T 31-10-2018 DFR85_00050 c65b8d4c712f81789374dec815c567ed 343 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 270 3.3E-32 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR85_00050 c65b8d4c712f81789374dec815c567ed 343 Gene3D G3DSA:3.50.50.100 1 342 2.9E-62 T 31-10-2018 DFR85_00050 c65b8d4c712f81789374dec815c567ed 343 SUPERFAMILY SSF51905 1 279 7.23E-24 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_12755 5cd4ff9688128f98f632b7c9960deb79 132 Gene3D G3DSA:3.40.50.1010 8 131 1.1E-10 T 31-10-2018 DFR85_12755 5cd4ff9688128f98f632b7c9960deb79 132 SUPERFAMILY SSF88723 7 125 9.81E-12 T 31-10-2018 IPR029060 PIN-like domain superfamily DFR85_12755 5cd4ff9688128f98f632b7c9960deb79 132 Pfam PF01850 PIN domain 25 124 4.8E-6 T 31-10-2018 IPR002716 PIN domain DFR85_00840 eca310299436ea639963a39a01f7d04e 139 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 6 129 6.5E-12 T 31-10-2018 IPR010419 Carbon monoxide dehydrogenase subunit G DFR85_15160 6efc982e1c69e0e50db601d96eb82897 224 Pfam PF04967 HTH DNA binding domain 162 214 1.8E-16 T 31-10-2018 IPR007050 Bacterioopsin activator-type, HTH domain DFR85_15620 9ed4079a9f3acd4443e9e208d0cbe8a2 191 Pfam PF03070 TENA/THI-4/PQQC family 8 190 2.1E-11 T 31-10-2018 IPR004305 Thiaminase-2/PQQC DFR85_15620 9ed4079a9f3acd4443e9e208d0cbe8a2 191 SUPERFAMILY SSF48613 2 189 8.7E-31 T 31-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 DFR85_15620 9ed4079a9f3acd4443e9e208d0cbe8a2 191 Gene3D G3DSA:1.20.910.10 1 191 4.2E-15 T 31-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 DFR85_11575 265b5fe8ac692a84066cf7efd7bd0253 185 Pfam PF00857 Isochorismatase family 14 179 3.0E-34 T 31-10-2018 IPR000868 Isochorismatase-like GO:0003824 DFR85_11575 265b5fe8ac692a84066cf7efd7bd0253 185 Gene3D G3DSA:3.40.50.850 1 181 1.3E-37 T 31-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 DFR85_11575 265b5fe8ac692a84066cf7efd7bd0253 185 SUPERFAMILY SSF52499 5 177 8.5E-40 T 31-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 DFR85_05885 7bc7b16c523051ff77ed78b90c1493d1 167 Gene3D G3DSA:2.40.50.100 85 167 6.3E-23 T 31-10-2018 DFR85_05885 7bc7b16c523051ff77ed78b90c1493d1 167 Pfam PF00364 Biotin-requiring enzyme 101 166 2.6E-16 T 31-10-2018 IPR000089 Biotin/lipoyl attachment DFR85_05885 7bc7b16c523051ff77ed78b90c1493d1 167 SUPERFAMILY SSF51230 91 166 1.11E-20 T 31-10-2018 IPR011053 Single hybrid motif DFR85_14075 90f8a88ba513d5a71759240839ae43c3 90 Gene3D G3DSA:1.10.10.10 1 90 3.5E-8 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_14075 90f8a88ba513d5a71759240839ae43c3 90 SUPERFAMILY SSF46785 8 87 2.88E-8 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_13510 59288f4ea8048c5ca139f1fd70a315fd 271 Pfam PF03787 RAMP superfamily 79 263 3.6E-12 T 31-10-2018 IPR005537 CRISPR type III-associated RAMP protein DFR85_03540 a3eeefcfb37ba81e00bef4d2849de331 232 SUPERFAMILY SSF53335 6 222 2.3E-26 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR85_03540 a3eeefcfb37ba81e00bef4d2849de331 232 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 20 35 - T 31-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 DFR85_03540 a3eeefcfb37ba81e00bef4d2849de331 232 Pfam PF01209 ubiE/COQ5 methyltransferase family 3 200 5.1E-22 T 31-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 DFR85_03540 a3eeefcfb37ba81e00bef4d2849de331 232 Gene3D G3DSA:3.40.50.150 16 223 1.5E-29 T 31-10-2018 DFR85_03920 97c03a4faa7b2e8859daa3c8a0f0a22b 246 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 15 226 9.3E-36 T 31-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 DFR85_03920 97c03a4faa7b2e8859daa3c8a0f0a22b 246 Gene3D G3DSA:3.40.50.300 3 227 3.9E-35 T 31-10-2018 DFR85_03920 97c03a4faa7b2e8859daa3c8a0f0a22b 246 SUPERFAMILY SSF52540 15 217 5.52E-23 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_14280 1d0fa9101d83d7e779234ff27267cbab 255 Pfam PF06053 Domain of unknown function (DUF929) 9 238 2.4E-52 T 31-10-2018 IPR009272 Protein of unknown function DUF929 DFR85_11430 dde98c4a64f5ddd03fc69c79659b7abe 438 Pfam PF02754 Cysteine-rich domain 233 331 4.0E-6 T 31-10-2018 IPR004017 Cysteine-rich domain DFR85_14705 bc3ae77c257c56ae4ba988526b324b32 370 Pfam PF07849 Protein of unknown function (DUF1641) 334 366 1.4E-6 T 31-10-2018 IPR012440 Protein of unknown function DUF1641 DFR85_14360 ac3971e72b3bf087706c3bb32a6f2b9c 309 Pfam PF04945 YHS domain 196 238 6.9E-15 T 31-10-2018 IPR007029 YHS domain DFR85_14360 ac3971e72b3bf087706c3bb32a6f2b9c 309 Gene3D G3DSA:1.10.620.20 17 298 1.9E-73 T 31-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 DFR85_14360 ac3971e72b3bf087706c3bb32a6f2b9c 309 SUPERFAMILY SSF47240 40 285 2.3E-59 T 31-10-2018 IPR009078 Ferritin-like superfamily DFR85_01030 a8ad65f0c9e8a4b0728eddf9a1506e2f 501 Pfam PF13632 Glycosyl transferase family group 2 158 366 3.4E-25 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 DFR85_01030 a8ad65f0c9e8a4b0728eddf9a1506e2f 501 SUPERFAMILY SSF53448 71 351 1.53E-39 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_01030 a8ad65f0c9e8a4b0728eddf9a1506e2f 501 Gene3D G3DSA:3.90.550.10 63 279 4.6E-51 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_03775 d3aa4ea7cec2a901d0be02c1009fb2cb 272 SUPERFAMILY SSF103501 160 257 5.62E-7 T 31-10-2018 IPR036197 NarG-like superfamily DFR85_06180 b741e10da8c3f06b756e727ace27e22b 197 Pfam PF07849 Protein of unknown function (DUF1641) 160 196 1.5E-9 T 31-10-2018 IPR012440 Protein of unknown function DUF1641 DFR85_14820 134550b2ce4f02143912d8e0cf14a67f 330 SMART SM00829 10 328 4.0E-10 T 31-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 DFR85_14820 134550b2ce4f02143912d8e0cf14a67f 330 Gene3D G3DSA:3.90.180.10 1 330 1.7E-79 T 31-10-2018 DFR85_14820 134550b2ce4f02143912d8e0cf14a67f 330 SUPERFAMILY SSF51735 137 295 1.55E-35 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_14820 134550b2ce4f02143912d8e0cf14a67f 330 SUPERFAMILY SSF50129 1 170 2.59E-43 T 31-10-2018 IPR011032 GroES-like superfamily DFR85_14820 134550b2ce4f02143912d8e0cf14a67f 330 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 132 1.1E-24 T 31-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 DFR85_14820 134550b2ce4f02143912d8e0cf14a67f 330 Pfam PF00107 Zinc-binding dehydrogenase 176 292 2.2E-21 T 31-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 DFR85_14845 519caa6ed052bced61a387ca82acca37 126 SUPERFAMILY SSF54909 21 102 6.97E-6 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel DFR85_06115 cc6145223ea4babbfa262900cbbf5590 93 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 28 91 2.7E-11 T 31-10-2018 IPR008792 Coenzyme PQQ synthesis D DFR85_06115 cc6145223ea4babbfa262900cbbf5590 93 Gene3D G3DSA:1.10.10.1150 14 93 3.7E-6 T 31-10-2018 DFR85_11385 f95772ba67a17e9ddd57a52d0845ce44 418 Pfam PF07849 Protein of unknown function (DUF1641) 376 414 4.3E-11 T 31-10-2018 IPR012440 Protein of unknown function DUF1641 DFR85_11385 f95772ba67a17e9ddd57a52d0845ce44 418 PIRSF PIRSF032762 254 418 1.2E-65 T 31-10-2018 IPR017007 Uncharacterised conserved protein UCP032762 DFR85_11385 f95772ba67a17e9ddd57a52d0845ce44 418 PIRSF PIRSF032762 1 266 2.6E-128 T 31-10-2018 IPR017007 Uncharacterised conserved protein UCP032762 DFR85_14885 6a83293dc033dedf28f58a68823d94a1 291 SUPERFAMILY SSF53448 49 252 1.25E-7 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_08210 a9b9fc108de318f1b959e3e51eb9f5d6 89 SUPERFAMILY SSF49764 11 87 5.63E-8 T 31-10-2018 IPR008978 HSP20-like chaperone DFR85_08210 a9b9fc108de318f1b959e3e51eb9f5d6 89 Gene3D G3DSA:2.60.40.790 4 89 4.1E-5 T 31-10-2018 IPR008978 HSP20-like chaperone DFR85_05530 0ffe5167065be0a4241569c2bb5849b6 596 Pfam PF00723 Glycosyl hydrolases family 15 396 537 7.8E-10 T 31-10-2018 IPR011613 GH15-like domain Reactome: R-HSA-70221 DFR85_05530 0ffe5167065be0a4241569c2bb5849b6 596 Gene3D G3DSA:1.50.10.10 242 594 1.8E-71 T 31-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 DFR85_05530 0ffe5167065be0a4241569c2bb5849b6 596 SUPERFAMILY SSF48208 220 591 6.43E-89 T 31-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 DFR85_12575 9d283dfec142a345669619df116baff0 252 Gene3D G3DSA:3.60.15.10 1 245 7.5E-24 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR85_12575 9d283dfec142a345669619df116baff0 252 SUPERFAMILY SSF56281 30 242 3.09E-11 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like DFR85_11195 4ccafc65e99bbcf5aa7146da730694bb 308 SUPERFAMILY SSF53335 64 286 6.92E-26 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR85_11195 4ccafc65e99bbcf5aa7146da730694bb 308 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 227 233 - T 31-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 DFR85_11195 4ccafc65e99bbcf5aa7146da730694bb 308 Gene3D G3DSA:3.40.50.150 135 307 6.7E-32 T 31-10-2018 DFR85_11195 4ccafc65e99bbcf5aa7146da730694bb 308 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 224 236 4.3E-6 T 31-10-2018 DFR85_11195 4ccafc65e99bbcf5aa7146da730694bb 308 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 164 178 4.3E-6 T 31-10-2018 DFR85_11195 4ccafc65e99bbcf5aa7146da730694bb 308 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 246 270 4.3E-6 T 31-10-2018 DFR85_11195 4ccafc65e99bbcf5aa7146da730694bb 308 Pfam PF01170 Putative RNA methylase family UPF0020 138 293 3.8E-21 T 31-10-2018 IPR000241 Putative RNA methylase domain DFR85_14865 6df7012ac40d00789fae53448e95e10e 401 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 255 330 1.4E-14 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR85_14865 6df7012ac40d00789fae53448e95e10e 401 Pfam PF01385 Probable transposase 181 287 9.8E-20 T 31-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 DFR85_14865 6df7012ac40d00789fae53448e95e10e 401 Pfam PF07282 Putative transposase DNA-binding domain 305 372 4.9E-23 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR85_02415 af8119f531a31e16cfbc3ab675545357 311 SUPERFAMILY SSF51735 1 281 7.24E-19 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_02415 af8119f531a31e16cfbc3ab675545357 311 Pfam PF04321 RmlD substrate binding domain 82 182 1.0E-5 T 31-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 DFR85_02415 af8119f531a31e16cfbc3ab675545357 311 Gene3D G3DSA:3.40.50.720 4 299 7.6E-24 T 31-10-2018 DFR85_06950 e4ac8123ea6d366622e5d20e466ade9a 167 Pfam PF07998 Peptidase family M54 40 163 3.7E-11 T 31-10-2018 IPR012962 Peptidase M54, archaemetzincin GO:0008270 DFR85_06950 e4ac8123ea6d366622e5d20e466ade9a 167 Gene3D G3DSA:3.40.390.10 2 163 2.4E-16 T 31-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 DFR85_09105 afbb4cb57b804128357bc0abcf673d31 400 SUPERFAMILY SSF82544 3 399 4.84E-90 T 31-10-2018 DFR85_09105 afbb4cb57b804128357bc0abcf673d31 400 Pfam PF05161 MOFRL family 292 393 6.7E-25 T 31-10-2018 IPR007835 MOFRL domain Reactome: R-HSA-70350 DFR85_09105 afbb4cb57b804128357bc0abcf673d31 400 Gene3D G3DSA:3.40.1480.10 239 395 2.6E-93 T 31-10-2018 IPR037035 Glycerate kinase-like, C-terminal domain superfamily DFR85_09105 afbb4cb57b804128357bc0abcf673d31 400 Gene3D G3DSA:3.40.50.10180 18 238 2.6E-93 T 31-10-2018 IPR038614 Glycerate kinase, N-terminal domain superfamily Reactome: R-HSA-70350 DFR85_09105 afbb4cb57b804128357bc0abcf673d31 400 Pfam PF13660 Domain of unknown function (DUF4147) 2 217 4.1E-51 T 31-10-2018 IPR025286 MOFRL-associated domain Reactome: R-HSA-70350 DFR85_06905 09e87c7992dc03fc91b01e607a8bbbe4 172 SUPERFAMILY SSF56300 3 156 7.17E-21 T 31-10-2018 DFR85_06905 09e87c7992dc03fc91b01e607a8bbbe4 172 Gene3D G3DSA:3.60.21.10 9 167 6.3E-9 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like DFR85_04035 578b2e4f7bfa472a10e9c38cd83a07d2 108 Pfam PF02635 DsrE/DsrF-like family 31 107 3.6E-7 T 31-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein DFR85_04035 578b2e4f7bfa472a10e9c38cd83a07d2 108 Gene3D G3DSA:3.40.1260.10 12 107 8.2E-9 T 31-10-2018 IPR027396 DsrEFH-like DFR85_04035 578b2e4f7bfa472a10e9c38cd83a07d2 108 SUPERFAMILY SSF75169 1 108 4.86E-20 T 31-10-2018 IPR027396 DsrEFH-like DFR85_01895 445af5677d29cc81b5e2ad621dfbea79 237 SUPERFAMILY SSF56317 2 220 1.16E-37 T 31-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily DFR85_01895 445af5677d29cc81b5e2ad621dfbea79 237 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 114 134 - T 31-10-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site DFR85_01895 445af5677d29cc81b5e2ad621dfbea79 237 Gene3D G3DSA:3.60.110.10 1 229 1.1E-37 T 31-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily DFR85_01895 445af5677d29cc81b5e2ad621dfbea79 237 Pfam PF00795 Carbon-nitrogen hydrolase 9 214 9.0E-17 T 31-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 DFR85_02720 cc52ac1effb1c361f14a531564532803 297 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 2 13 - T 31-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 DFR85_02720 cc52ac1effb1c361f14a531564532803 297 Pfam PF13394 4Fe-4S single cluster domain 5 67 8.6E-7 T 31-10-2018 DFR85_02720 cc52ac1effb1c361f14a531564532803 297 Gene3D G3DSA:3.20.20.70 1 270 1.2E-37 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 DFR85_02720 cc52ac1effb1c361f14a531564532803 297 SUPERFAMILY SSF102114 2 260 9.81E-36 T 31-10-2018 DFR85_02720 cc52ac1effb1c361f14a531564532803 297 Pfam PF04055 Radical SAM superfamily 4 165 2.4E-15 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 DFR85_13560 01d04a06011040e9ad7d408f7fea5edb 526 PIRSF PIRSF006060 1 476 1.7E-57 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_13560 01d04a06011040e9ad7d408f7fea5edb 526 PIRSF PIRSF006060 407 523 71.0 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_13560 01d04a06011040e9ad7d408f7fea5edb 526 Pfam PF13520 Amino acid permease 15 461 8.1E-23 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_13560 01d04a06011040e9ad7d408f7fea5edb 526 Gene3D G3DSA:1.20.1740.10 10 456 2.8E-42 T 31-10-2018 DFR85_15375 168b995735870f6b7a022c2e0f42a4b2 182 Pfam PF06197 Protein of unknown function (DUF998) 9 173 2.3E-29 T 31-10-2018 IPR009339 Protein of unknown function DUF998 DFR85_09000 d8fd3db0a22ee7ccf303061b76b74fc4 433 Pfam PF00534 Glycosyl transferases group 1 242 399 2.2E-14 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 DFR85_09000 d8fd3db0a22ee7ccf303061b76b74fc4 433 Gene3D G3DSA:3.40.50.2000 99 207 5.3E-21 T 31-10-2018 DFR85_09000 d8fd3db0a22ee7ccf303061b76b74fc4 433 Gene3D G3DSA:3.40.50.2000 208 401 5.3E-21 T 31-10-2018 DFR85_09000 d8fd3db0a22ee7ccf303061b76b74fc4 433 SUPERFAMILY SSF53756 18 399 5.76E-29 T 31-10-2018 DFR85_13170 5d3c1c6e943cad8b95319b9ccb58f054 176 Pfam PF03787 RAMP superfamily 38 164 4.9E-8 T 31-10-2018 IPR005537 CRISPR type III-associated RAMP protein DFR85_12550 e8919dd19729e2ce25969722bbe30996 155 Pfam PF05942 Archaeal PaREP1/PaREP8 family 35 147 1.7E-34 T 31-10-2018 IPR010268 Archaeal PaREP1 DFR85_12550 e8919dd19729e2ce25969722bbe30996 155 Gene3D G3DSA:1.20.120.330 35 155 1.6E-36 T 31-10-2018 DFR85_00030 fba77716c12f7176708078eb104d2a13 171 SUPERFAMILY SSF49503 77 170 1.39E-15 T 31-10-2018 IPR008972 Cupredoxin DFR85_00030 fba77716c12f7176708078eb104d2a13 171 Gene3D G3DSA:2.60.40.420 55 171 1.4E-10 T 31-10-2018 IPR008972 Cupredoxin DFR85_02685 b3527349c3575d618a0ab665c257d6f0 495 Pfam PF13520 Amino acid permease 17 434 3.8E-12 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_02685 b3527349c3575d618a0ab665c257d6f0 495 PIRSF PIRSF006060 1 487 1.2E-27 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_02685 b3527349c3575d618a0ab665c257d6f0 495 Gene3D G3DSA:1.20.1740.10 11 459 2.5E-18 T 31-10-2018 DFR85_13115 d13ce1b5eed95e2d314816288c337069 110 Pfam PF01909 Nucleotidyltransferase domain 22 97 7.2E-8 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 DFR85_13115 d13ce1b5eed95e2d314816288c337069 110 SUPERFAMILY SSF81301 11 105 3.97E-13 T 31-10-2018 DFR85_13115 d13ce1b5eed95e2d314816288c337069 110 Gene3D G3DSA:3.30.460.10 8 108 7.8E-11 T 31-10-2018 DFR85_01070 0fd78a79c1850193ee7135d7e62ef475 92 Pfam PF03477 ATP cone domain 1 69 1.4E-5 T 31-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 DFR85_15580 ec13aa75b13d3d45a0788b626179bedf 180 Pfam PF04173 TQO small subunit DoxD 10 167 7.7E-50 T 31-10-2018 IPR007301 TQO small subunit DoxD KEGG: 00920+1.8.5.2|MetaCyc: PWY-5303 DFR85_14495 58658b1548bfa8a4ad5ee7410f22dbfc 158 SUPERFAMILY SSF48371 20 150 5.76E-8 T 31-10-2018 IPR016024 Armadillo-type fold DFR85_00625 64e82457853eaef934555fd24d920c08 98 Gene3D G3DSA:3.30.1860.10 1 98 9.2E-23 T 31-10-2018 DFR85_00625 64e82457853eaef934555fd24d920c08 98 Pfam PF04242 Protein of unknown function (DUF424) 11 98 2.0E-25 T 31-10-2018 IPR007355 Protein of unknown function DUF424 DFR85_12860 c9cbcc563008f2bbee7ce7d6f6a34ed2 475 Pfam PF09455 CRISPR-associated (Cas) DxTHG family 8 426 2.5E-28 T 31-10-2018 IPR019016 CRISPR-associated DxTHG protein DFR85_12860 c9cbcc563008f2bbee7ce7d6f6a34ed2 475 Gene3D G3DSA:3.40.50.10640 5 193 2.1E-11 T 31-10-2018 DFR85_12860 c9cbcc563008f2bbee7ce7d6f6a34ed2 475 SUPERFAMILY SSF160980 7 439 6.67E-37 T 31-10-2018 DFR85_00210 261acaaae32d0d4c4940f03f17796359 187 Pfam PF07185 Protein of unknown function (DUF1404) 15 183 5.9E-58 T 31-10-2018 IPR009844 Protein of unknown function DUF1404 DFR85_11535 ac13e4f367cf11993eabe791897a7993 433 Gene3D G3DSA:1.10.490.140 164 247 4.0E-5 T 31-10-2018 DFR85_11535 ac13e4f367cf11993eabe791897a7993 433 TIGRFAM TIGR03604 TOMM_cyclo_SagD: thiazole/oxazole-forming peptide maturase, SagD family component 73 433 1.3E-67 T 31-10-2018 IPR027624 Thiazole/oxazole-forming peptide maturase, SagD family component DFR85_11535 ac13e4f367cf11993eabe791897a7993 433 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 73 394 3.1E-43 T 31-10-2018 IPR003776 YcaO-like domain DFR85_06805 09e9f77c43425d0ef150dd8a11ebd3b0 612 Pfam PF04312 Protein of unknown function (DUF460) 219 359 6.7E-47 T 31-10-2018 IPR007408 Protein of unknown function DUF460 DFR85_03085 1416c1a2c408e64ab64ecac9e346bb9d 234 SUPERFAMILY SSF56235 4 207 3.55E-11 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR85_03085 1416c1a2c408e64ab64ecac9e346bb9d 234 Gene3D G3DSA:3.60.20.10 1 195 1.2E-14 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal DFR85_12615 b2c33419927552ac82e813e66a8be382 176 Pfam PF05942 Archaeal PaREP1/PaREP8 family 19 137 1.0E-24 T 31-10-2018 IPR010268 Archaeal PaREP1 DFR85_09500 821c5230cad8049f12310c544781c235 290 Gene3D G3DSA:3.50.50.60 1 221 1.4E-9 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_04825 122b5e02db9791045ec128dbe6800663 363 TIGRFAM TIGR01765 tspaseT_teng_N: transposase, putative, N-terminal domain 20 90 1.6E-19 T 31-10-2018 IPR010094 Transposase (putative), N-terminal DFR85_02365 0e03488ed64b90b2a517d830fa52fb76 262 SUPERFAMILY SSF74650 3 258 5.84E-50 T 31-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 DFR85_02365 0e03488ed64b90b2a517d830fa52fb76 262 Gene3D G3DSA:2.70.98.10 1 259 1.0E-51 T 31-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 DFR85_02365 0e03488ed64b90b2a517d830fa52fb76 262 Pfam PF01263 Aldose 1-epimerase 3 257 1.6E-31 T 31-10-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 DFR85_10400 01fb830cccd2291c95b0b97060182a7e 377 SUPERFAMILY SSF101960 21 372 2.35E-52 T 31-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily DFR85_10400 01fb830cccd2291c95b0b97060182a7e 377 Pfam PF01458 Uncharacterized protein family (UPF0051) 160 354 6.3E-36 T 31-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 DFR85_02775 76a5f87eda37f251d65f54db7d592ddd 267 SUPERFAMILY SSF56317 1 260 5.89E-64 T 31-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily DFR85_02775 76a5f87eda37f251d65f54db7d592ddd 267 Pfam PF00795 Carbon-nitrogen hydrolase 2 251 1.5E-51 T 31-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 DFR85_02775 76a5f87eda37f251d65f54db7d592ddd 267 Gene3D G3DSA:3.60.110.10 1 266 1.6E-71 T 31-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily DFR85_11250 3388c5764681ab2cdeeab6cbf7308869 337 SUPERFAMILY SSF53850 35 313 5.6E-17 T 31-10-2018 DFR85_11250 3388c5764681ab2cdeeab6cbf7308869 337 Gene3D G3DSA:3.40.190.10 118 274 3.0E-37 T 31-10-2018 DFR85_11250 3388c5764681ab2cdeeab6cbf7308869 337 Gene3D G3DSA:3.40.190.10 38 322 3.0E-37 T 31-10-2018 DFR85_11250 3388c5764681ab2cdeeab6cbf7308869 337 Pfam PF13531 Bacterial extracellular solute-binding protein 37 291 2.4E-17 T 31-10-2018 DFR85_08625 b0f6df316ec3d304bc2c2c301aac8bed 427 Gene3D G3DSA:3.30.450.380 1 152 2.6E-8 T 31-10-2018 DFR85_02145 82715ab6853ac88a4dada79b2d0072d3 512 Pfam PF02538 Hydantoinase B/oxoprolinase 2 506 4.3E-175 T 31-10-2018 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 DFR85_06590 c7d139c4b85e881b8eb5e1d5c802f04e 597 SUPERFAMILY SSF52540 238 589 5.6E-37 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_06590 c7d139c4b85e881b8eb5e1d5c802f04e 597 SMART SM00382 275 543 0.0014 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_06590 c7d139c4b85e881b8eb5e1d5c802f04e 597 Pfam PF01935 Domain of unknown function DUF87 262 454 1.5E-7 T 31-10-2018 IPR002789 Helicase HerA, central domain DFR85_06870 8f57ba680d0b9c3bf8634c54ad2a80d4 387 SUPERFAMILY SSF51905 119 245 4.31E-23 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_06870 8f57ba680d0b9c3bf8634c54ad2a80d4 387 SUPERFAMILY SSF51905 2 310 4.62E-21 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_06870 8f57ba680d0b9c3bf8634c54ad2a80d4 387 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 118 4.0E-15 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR85_06870 8f57ba680d0b9c3bf8634c54ad2a80d4 387 Gene3D G3DSA:3.50.50.60 112 256 2.5E-70 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_06870 8f57ba680d0b9c3bf8634c54ad2a80d4 387 Gene3D G3DSA:3.50.50.60 4 310 2.5E-70 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_12385 9fa959899eef9f793d74bd052ff3e488 212 Pfam PF13649 Methyltransferase domain 3 104 1.7E-6 T 31-10-2018 DFR85_12385 9fa959899eef9f793d74bd052ff3e488 212 SUPERFAMILY SSF53335 2 149 2.65E-13 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR85_12385 9fa959899eef9f793d74bd052ff3e488 212 Gene3D G3DSA:3.40.50.150 1 152 6.4E-11 T 31-10-2018 DFR85_14825 5f6031d2827d732ea4548ac933bd3b3f 213 SUPERFAMILY SSF47240 37 203 1.75E-9 T 31-10-2018 IPR009078 Ferritin-like superfamily DFR85_14825 5f6031d2827d732ea4548ac933bd3b3f 213 Gene3D G3DSA:1.10.620.20 2 211 3.1E-18 T 31-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 DFR85_13995 4d56c3d942579019dac97431daa82708 222 Pfam PF13349 Putative adhesin 24 203 1.4E-12 T 31-10-2018 IPR025164 Putative adhesin DFR85_09605 c99f4c860b5b70fa5db5bbb8036842cd 100 SUPERFAMILY SSF159468 4 99 1.31E-17 T 31-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 DFR85_09605 c99f4c860b5b70fa5db5bbb8036842cd 100 Gene3D G3DSA:3.40.50.10580 5 99 5.6E-16 T 31-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 DFR85_09605 c99f4c860b5b70fa5db5bbb8036842cd 100 Pfam PF01990 ATP synthase (F/14-kDa) subunit 4 89 2.6E-13 T 31-10-2018 IPR008218 ATPase, V1 complex, subunit F GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 DFR85_04885 bebf8b42a0aeb9e0fb6e775646146126 304 Pfam PF03787 RAMP superfamily 17 299 3.1E-19 T 31-10-2018 IPR005537 CRISPR type III-associated RAMP protein DFR85_04885 bebf8b42a0aeb9e0fb6e775646146126 304 TIGRFAM TIGR02580 cas_RAMP_Cmr4: CRISPR type III-B/RAMP module RAMP protein Cmr4 13 299 2.4E-64 T 31-10-2018 IPR013410 CRISPR-associated RAMP Cmr4 DFR85_14980 243df886fb1a3829846f5e6dd8396073 117 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 17 46 6.6E-10 T 31-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal DFR85_14980 243df886fb1a3829846f5e6dd8396073 117 SUPERFAMILY SSF50249 3 108 6.0E-22 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR85_14980 243df886fb1a3829846f5e6dd8396073 117 Gene3D G3DSA:1.10.12.20 3 49 6.7E-6 T 31-10-2018 DFR85_05635 87f33d9fb886abf8006094a8f3f69353 615 Pfam PF12222 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A 92 366 2.5E-27 T 31-10-2018 IPR021102 Peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase A DFR85_04010 b0b9b337f2f3b522b0c30890c7fbae03 325 SUPERFAMILY SSF103473 77 323 2.35E-7 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_00075 75783ab368d6a6689ca2dea895189801 150 Pfam PF04982 HPP family 35 143 2.9E-7 T 31-10-2018 IPR007065 HPP DFR85_10510 9c93c6bb1f0a8d23d540eef0514021cc 204 Gene3D G3DSA:1.10.1670.10 16 204 4.9E-58 T 31-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 DFR85_10510 9c93c6bb1f0a8d23d540eef0514021cc 204 SUPERFAMILY SSF48150 29 199 4.01E-20 T 31-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 DFR85_10510 9c93c6bb1f0a8d23d540eef0514021cc 204 PIRSF PIRSF005954 1 204 8.6E-71 T 31-10-2018 IPR012092 8-oxoguanine DNA glycosylase/DNA lyase, thermostable GO:0003906|GO:0006281|GO:0016799 DFR85_10510 9c93c6bb1f0a8d23d540eef0514021cc 204 Gene3D G3DSA:1.10.340.30 28 140 4.9E-58 T 31-10-2018 DFR85_10510 9c93c6bb1f0a8d23d540eef0514021cc 204 Hamap MF_00241 Probable N-glycosylase/DNA lyase [ogg]. 1 204 29.41 T 31-10-2018 IPR012092 8-oxoguanine DNA glycosylase/DNA lyase, thermostable GO:0003906|GO:0006281|GO:0016799 DFR85_10510 9c93c6bb1f0a8d23d540eef0514021cc 204 SMART SM00478 42 199 0.0018 T 31-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 DFR85_14365 d707197e90268c8bb8952e2300273a31 148 Pfam PF03928 Haem-degrading 7 129 2.1E-30 T 31-10-2018 IPR005624 Haem-degrading DFR85_14365 d707197e90268c8bb8952e2300273a31 148 SUPERFAMILY SSF143744 4 136 6.54E-38 T 31-10-2018 IPR038084 GlcG-like domain superfamily DFR85_14365 d707197e90268c8bb8952e2300273a31 148 Gene3D G3DSA:3.30.450.150 1 141 7.5E-44 T 31-10-2018 IPR038084 GlcG-like domain superfamily DFR85_10620 af49ddab3f6787ff68bf5c9db5bc6cae 480 Gene3D G3DSA:3.40.1670.10 325 441 4.5E-36 T 31-10-2018 DFR85_10620 af49ddab3f6787ff68bf5c9db5bc6cae 480 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 442 2.9E-121 T 31-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 DFR85_10620 af49ddab3f6787ff68bf5c9db5bc6cae 480 SUPERFAMILY SSF50475 3 310 3.77E-85 T 31-10-2018 DFR85_10620 af49ddab3f6787ff68bf5c9db5bc6cae 480 SUPERFAMILY SSF143968 311 471 1.14E-53 T 31-10-2018 DFR85_10620 af49ddab3f6787ff68bf5c9db5bc6cae 480 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 10 417 4.8E-122 T 31-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 DFR85_05335 107cbeebb4ed1ee8faeabc1b57e25cc5 182 Pfam PF13240 zinc-ribbon domain 159 181 2.3E-8 T 31-10-2018 IPR026870 Zinc-ribbon domain Reactome: R-HSA-202670 DFR85_14410 e795b7ab7441febdc35eda6f9078a827 271 Gene3D G3DSA:2.40.400.10 5 267 3.8E-65 T 31-10-2018 IPR023375 Acetoacetate decarboxylase domain superfamily KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 DFR85_14410 e795b7ab7441febdc35eda6f9078a827 271 Pfam PF06314 Acetoacetate decarboxylase (ADC) 11 262 1.7E-56 T 31-10-2018 IPR010451 Acetoacetate decarboxylase GO:0016829 KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 DFR85_14410 e795b7ab7441febdc35eda6f9078a827 271 SUPERFAMILY SSF160104 21 258 6.41E-38 T 31-10-2018 IPR023375 Acetoacetate decarboxylase domain superfamily KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 DFR85_03355 5b1b368383d2e8bb1bb7468d0c54cdb5 135 Gene3D G3DSA:3.30.460.10 12 122 2.3E-12 T 31-10-2018 DFR85_03355 5b1b368383d2e8bb1bb7468d0c54cdb5 135 Pfam PF01909 Nucleotidyltransferase domain 24 98 9.5E-9 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 DFR85_03355 5b1b368383d2e8bb1bb7468d0c54cdb5 135 SUPERFAMILY SSF81301 23 112 2.42E-11 T 31-10-2018 DFR85_09850 8417c31c1f1ee3b0bf96a34bcf631c7d 82 Gene3D G3DSA:3.30.310.50 1 78 3.0E-6 T 31-10-2018 DFR85_02700 275286fee08a1c2596b7ea0802813ab1 351 Gene3D G3DSA:3.40.50.720 38 330 2.0E-43 T 31-10-2018 DFR85_02700 275286fee08a1c2596b7ea0802813ab1 351 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 4 113 4.7E-13 T 31-10-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 DFR85_02700 275286fee08a1c2596b7ea0802813ab1 351 SUPERFAMILY SSF51735 1 131 2.5E-13 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily DFR85_02700 275286fee08a1c2596b7ea0802813ab1 351 Gene3D G3DSA:3.30.360.10 119 295 2.0E-43 T 31-10-2018 DFR85_11505 58b603dad0cbf07bfe8d11b3f6e80eef 97 SMART SM00418 8 93 0.0094 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 DFR85_11505 58b603dad0cbf07bfe8d11b3f6e80eef 97 SUPERFAMILY SSF46785 20 94 8.95E-10 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_11505 58b603dad0cbf07bfe8d11b3f6e80eef 97 Pfam PF13601 Winged helix DNA-binding domain 20 95 1.3E-11 T 31-10-2018 IPR027395 Winged helix DNA-binding domain DFR85_11505 58b603dad0cbf07bfe8d11b3f6e80eef 97 Gene3D G3DSA:1.10.10.10 3 96 2.0E-14 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_13005 98ecd24b351b9c027e85ce57409094b8 187 Gene3D G3DSA:3.40.1050.10 2 129 1.7E-10 T 31-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 DFR85_13005 98ecd24b351b9c027e85ce57409094b8 187 Pfam PF00484 Carbonic anhydrase 4 118 1.2E-5 T 31-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 DFR85_13005 98ecd24b351b9c027e85ce57409094b8 187 SUPERFAMILY SSF53056 4 130 6.41E-15 T 31-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 DFR85_11580 835e05ff3de11d0e0b21ac7d0cf7e789 368 Gene3D G3DSA:1.20.1250.20 1 188 2.3E-15 T 31-10-2018 DFR85_11580 835e05ff3de11d0e0b21ac7d0cf7e789 368 Gene3D G3DSA:1.20.1250.20 191 368 4.2E-8 T 31-10-2018 DFR85_11580 835e05ff3de11d0e0b21ac7d0cf7e789 368 SUPERFAMILY SSF103473 5 367 1.7E-29 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_11580 835e05ff3de11d0e0b21ac7d0cf7e789 368 Pfam PF07690 Major Facilitator Superfamily 8 186 9.9E-15 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 DFR85_08050 466bed9c07a2ac8703fc447e7b232423 68 Pfam PF08394 Archaeal TRASH domain 14 48 2.1E-6 T 31-10-2018 IPR013603 TRASH transcription regulator C-terminal, archaeal DFR85_04735 38b6beca86713a99900b83c390eebc0f 129 Pfam PF04693 Archaeal putative transposase ISC1217 16 129 4.6E-43 T 31-10-2018 IPR006783 Transposase, ISC1217 DFR85_01615 3b1c18d609f8649680067a93ce330aac 122 Pfam PF01957 NfeD-like C-terminal, partner-binding 9 115 2.5E-17 T 31-10-2018 IPR002810 NfeD-like, C-terminal domain DFR85_01615 3b1c18d609f8649680067a93ce330aac 122 Gene3D G3DSA:2.40.50.140 49 120 6.0E-19 T 31-10-2018 DFR85_01615 3b1c18d609f8649680067a93ce330aac 122 SUPERFAMILY SSF141322 54 114 2.75E-17 T 31-10-2018 DFR85_05360 dafdc673a4103ff396e59f5ddf347892 66 Pfam PF11755 Protein of unknown function (DUF3311) 12 56 1.8E-10 T 31-10-2018 IPR021741 Protein of unknown function DUF3311 DFR85_08380 5b0ae30d35d80923a3a60b3372221b09 409 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 203 323 9.8E-8 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR85_08380 5b0ae30d35d80923a3a60b3372221b09 409 Gene3D G3DSA:3.50.50.60 4 333 1.8E-113 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_08380 5b0ae30d35d80923a3a60b3372221b09 409 Gene3D G3DSA:3.50.50.60 115 276 1.8E-113 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_08380 5b0ae30d35d80923a3a60b3372221b09 409 SUPERFAMILY SSF51905 3 334 8.16E-28 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_08380 5b0ae30d35d80923a3a60b3372221b09 409 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 143 1.3E-12 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 DFR85_08380 5b0ae30d35d80923a3a60b3372221b09 409 SUPERFAMILY SSF51905 119 267 2.29E-8 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily DFR85_13885 6e82463ee05d447a512556f2fe5120e5 297 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 47 203 6.1E-23 T 31-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 DFR85_13885 6e82463ee05d447a512556f2fe5120e5 297 Gene3D G3DSA:3.40.50.970 4 90 6.9E-7 T 31-10-2018 DFR85_13885 6e82463ee05d447a512556f2fe5120e5 297 Gene3D G3DSA:3.40.50.970 91 297 7.8E-68 T 31-10-2018 DFR85_13885 6e82463ee05d447a512556f2fe5120e5 297 SUPERFAMILY SSF52518 13 295 1.53E-75 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR85_09775 51af710689f0aac64d10b97e3c2c72bf 438 Pfam PF01964 Radical SAM ThiC family 2 418 4.2E-174 T 31-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 DFR85_09775 51af710689f0aac64d10b97e3c2c72bf 438 Gene3D G3DSA:3.20.20.540 41 362 5.8E-129 T 31-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 DFR85_09775 51af710689f0aac64d10b97e3c2c72bf 438 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 1 418 3.2E-165 T 31-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 DFR85_00415 5d062a5407f4c0ec3646482e2dd7182d 198 Gene3D G3DSA:3.90.420.10 11 196 4.4E-50 T 31-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 DFR85_00415 5d062a5407f4c0ec3646482e2dd7182d 198 Pfam PF00174 Oxidoreductase molybdopterin binding domain 22 167 3.6E-39 T 31-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 DFR85_00415 5d062a5407f4c0ec3646482e2dd7182d 198 SUPERFAMILY SSF56524 6 185 1.15E-61 T 31-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 DFR85_08765 bd7a3cc1e33515b3767c7a533682ebf5 187 SUPERFAMILY SSF81301 40 134 3.27E-5 T 31-10-2018 DFR85_06370 62e6cbff0ee7599a71974876e17b4ff8 275 Pfam PF07282 Putative transposase DNA-binding domain 206 269 4.5E-19 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR85_11390 b3f74c8e0f7f86043dc0eace0b84cb03 104 Gene3D G3DSA:3.40.50.1010 1 104 3.9E-40 T 31-10-2018 DFR85_08115 f7fcb64665aaf7d2e1d2e2e3990f509a 88 Pfam PF01998 Protein of unknown function DUF131 29 74 9.7E-9 T 31-10-2018 IPR002849 Protein of unknown function DUF131 DFR85_02670 c5b4800dfc48ccf40b857484d7613e13 304 SUPERFAMILY SSF51556 1 302 4.42E-48 T 31-10-2018 IPR032466 Metal-dependent hydrolase DFR85_02670 c5b4800dfc48ccf40b857484d7613e13 304 Gene3D G3DSA:3.20.20.140 1 303 4.2E-57 T 31-10-2018 DFR85_02670 c5b4800dfc48ccf40b857484d7613e13 304 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 3 299 2.2E-59 T 31-10-2018 IPR008257 Peptidase M19 GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 DFR85_12075 36ed146f6211c260ad18d65b5b1d3978 131 SUPERFAMILY SSF50249 2 111 5.14E-27 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold DFR85_12075 36ed146f6211c260ad18d65b5b1d3978 131 Gene3D G3DSA:2.40.50.140 9 108 1.9E-30 T 31-10-2018 DFR85_03270 f2804f58d81ddbe683920e5182585822 72 Pfam PF09339 IclR helix-turn-helix domain 26 56 1.8E-7 T 31-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 DFR85_03270 f2804f58d81ddbe683920e5182585822 72 Gene3D G3DSA:1.10.10.10 8 72 3.9E-12 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_03270 f2804f58d81ddbe683920e5182585822 72 SUPERFAMILY SSF46785 5 69 7.23E-13 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_10025 c0a77c1987b15fbb2ee074deacfc1800 171 Gene3D G3DSA:2.160.10.10 1 170 1.1E-61 T 31-10-2018 DFR85_10025 c0a77c1987b15fbb2ee074deacfc1800 171 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 12 45 1.2E-5 T 31-10-2018 IPR001451 Hexapeptide repeat DFR85_10025 c0a77c1987b15fbb2ee074deacfc1800 171 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 88 122 6.4E-8 T 31-10-2018 IPR001451 Hexapeptide repeat DFR85_10025 c0a77c1987b15fbb2ee074deacfc1800 171 SUPERFAMILY SSF51161 4 167 2.36E-47 T 31-10-2018 IPR011004 Trimeric LpxA-like superfamily DFR85_05055 954e8ce71e31264e06d9b313a1df11a1 136 Gene3D G3DSA:3.40.50.1010 4 135 5.5E-14 T 31-10-2018 DFR85_05055 954e8ce71e31264e06d9b313a1df11a1 136 SUPERFAMILY SSF88723 4 127 1.55E-15 T 31-10-2018 IPR029060 PIN-like domain superfamily DFR85_05055 954e8ce71e31264e06d9b313a1df11a1 136 Pfam PF01850 PIN domain 5 128 3.0E-11 T 31-10-2018 IPR002716 PIN domain DFR85_08005 1236702f83b214288fb52cfed92e74b6 322 SUPERFAMILY SSF103486 7 317 8.5E-8 T 31-10-2018 IPR036079 V-type ATP synthase subunit C-like Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 DFR85_08005 1236702f83b214288fb52cfed92e74b6 322 Pfam PF01992 ATP synthase (C/AC39) subunit 13 314 5.2E-13 T 31-10-2018 IPR002843 ATPase, V0 complex, c/d subunit Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 DFR85_05840 9e9dc32b031ca62cf9fe4bb8d090d785 382 Pfam PF05559 Protein of unknown function (DUF763) 5 338 2.8E-119 T 31-10-2018 IPR008482 Protein of unknown function DUF763 DFR85_10950 2cf838dfd9447c083e52afe1505ca308 59 Pfam PF11520 Chromatin protein Cren7 1 58 4.0E-32 T 31-10-2018 IPR020906 Double-stranded DNA-binding Cren7 GO:0003690|GO:0005737 DFR85_10950 2cf838dfd9447c083e52afe1505ca308 59 Gene3D G3DSA:2.30.30.610 4 59 2.9E-32 T 31-10-2018 IPR038647 Cren7 superfamily DFR85_10950 2cf838dfd9447c083e52afe1505ca308 59 Hamap MF_01387 Chromatin protein Cren7 [creN7]. 1 58 20.114 T 31-10-2018 IPR020906 Double-stranded DNA-binding Cren7 GO:0003690|GO:0005737 DFR85_07200 9b62ea7c242148684331bce27611487a 185 SUPERFAMILY SSF89550 4 178 7.45E-13 T 31-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 DFR85_07200 9b62ea7c242148684331bce27611487a 185 Gene3D G3DSA:3.20.20.140 1 181 4.3E-12 T 31-10-2018 DFR85_04670 645ad9800b839c8cdb0e28767b9589dc 46 Pfam PF05942 Archaeal PaREP1/PaREP8 family 5 36 8.0E-6 T 31-10-2018 IPR010268 Archaeal PaREP1 DFR85_04670 645ad9800b839c8cdb0e28767b9589dc 46 Gene3D G3DSA:1.20.120.330 3 46 6.0E-7 T 31-10-2018 DFR85_14470 ba1905dc5569ee4d4ef793e10ee9ba58 182 Pfam PF13847 Methyltransferase domain 36 141 1.1E-18 T 31-10-2018 IPR025714 Methyltransferase domain DFR85_14470 ba1905dc5569ee4d4ef793e10ee9ba58 182 SUPERFAMILY SSF53335 26 147 5.21E-26 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR85_14470 ba1905dc5569ee4d4ef793e10ee9ba58 182 Gene3D G3DSA:3.40.50.150 14 175 3.8E-32 T 31-10-2018 DFR85_13750 6fdcf54a2105565fe0c42c55bdd81c32 311 Pfam PF06157 Protein of unknown function (DUF973) 31 310 4.7E-76 T 31-10-2018 IPR009321 Protein of unknown function DUF973 DFR85_04230 4daa6ded587de06713560b965e530d61 158 SUPERFAMILY SSF88723 15 139 1.6E-9 T 31-10-2018 IPR029060 PIN-like domain superfamily DFR85_04230 4daa6ded587de06713560b965e530d61 158 Gene3D G3DSA:3.40.50.1010 14 148 2.6E-15 T 31-10-2018 DFR85_04230 4daa6ded587de06713560b965e530d61 158 Pfam PF01850 PIN domain 15 139 1.3E-8 T 31-10-2018 IPR002716 PIN domain DFR85_15290 27c7939afd53c2fb6abdd0b5e758612a 369 SUPERFAMILY SSF103473 21 342 5.32E-7 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_00355 95ea6e1a5cc66b63d421036e6ba6b1ee 166 Pfam PF07680 TQO small subunit DoxA 27 152 6.3E-27 T 31-10-2018 IPR011636 Thiosulphate:quinone oxidoreductase small subunit DoxA KEGG: 00920+1.8.5.2|MetaCyc: PWY-5303 DFR85_01650 da278e6a5aa3728d9653d67593bb8f74 121 PIRSF PIRSF016498 2 121 3.1E-49 T 31-10-2018 IPR018699 Protein of unknown function DUF2203 DFR85_01650 da278e6a5aa3728d9653d67593bb8f74 121 Pfam PF09969 Uncharacterized conserved protein (DUF2203) 5 111 4.2E-28 T 31-10-2018 IPR018699 Protein of unknown function DUF2203 DFR85_05230 6164e8afc7379f2cd57b773521b01b4e 323 Pfam PF01944 Stage II sporulation protein M 10 157 9.1E-10 T 31-10-2018 IPR002798 Stage II sporulation protein M-like DFR85_11765 27baca7749407048f22eabc131a3ce2f 622 PIRSF PIRSF006060 489 557 9.2 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_11765 27baca7749407048f22eabc131a3ce2f 622 PIRSF PIRSF006060 554 609 150.0 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_11765 27baca7749407048f22eabc131a3ce2f 622 PIRSF PIRSF006060 8 493 3.1E-68 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_11765 27baca7749407048f22eabc131a3ce2f 622 Pfam PF13520 Amino acid permease 26 468 2.6E-33 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_11765 27baca7749407048f22eabc131a3ce2f 622 Gene3D G3DSA:1.20.1740.10 20 494 1.0E-57 T 31-10-2018 DFR85_01970 3d2846d97120deff951cd5701734f17f 197 Gene3D G3DSA:3.90.850.10 2 152 1.3E-7 T 31-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 DFR85_01970 3d2846d97120deff951cd5701734f17f 197 SUPERFAMILY SSF56529 3 187 6.59E-10 T 31-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 DFR85_01455 d6edb9ffde11e33ce4835d821e2da785 103 Gene3D G3DSA:2.20.28.10 6 103 9.6E-26 T 31-10-2018 DFR85_01455 d6edb9ffde11e33ce4835d821e2da785 103 SUPERFAMILY SSF46785 4 102 3.4E-29 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_02730 d90544004b0e84eb5f27a7d11cf9782a 294 SUPERFAMILY SSF103473 30 283 2.22E-6 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_15510 ff38edcd2ce4a447996216fb4512a115 158 SUPERFAMILY SSF103473 2 153 5.62E-5 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_02075 b67fd5f8977b3f5f2efc0c574d01caf9 313 Pfam PF00146 NADH dehydrogenase 11 307 1.7E-33 T 31-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_00150 8e61411527c5d7bd3cf97dd0faf24a9b 383 Pfam PF02371 Transposase IS116/IS110/IS902 family 236 317 4.5E-23 T 31-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 DFR85_00150 8e61411527c5d7bd3cf97dd0faf24a9b 383 Pfam PF01548 Transposase 12 154 2.3E-20 T 31-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 DFR85_00590 450fd8b5b13fe7af323908dc8e200c26 179 SUPERFAMILY SSF52980 31 92 2.28E-6 T 31-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 DFR85_02995 9bfef8a1ae4f24f17d3f65e0da8f0e13 108 SUPERFAMILY SSF50998 3 102 2.04E-5 T 31-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily DFR85_09705 98563af1deaaa3157007c7ea94e40a5f 129 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 29 118 2.4E-8 T 31-10-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_09705 98563af1deaaa3157007c7ea94e40a5f 129 Gene3D G3DSA:1.20.58.1610 1 125 1.2E-7 T 31-10-2018 IPR038430 NADH:ubiquinone oxidoreductase, subunit 3 superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_11050 e5757aaa836db755ff757e7ccd6f3bf5 169 Pfam PF01931 Protein of unknown function DUF84 6 165 1.6E-30 T 31-10-2018 IPR026533 Non-canonical purine NTP phosphatase/PRRC1 DFR85_11050 e5757aaa836db755ff757e7ccd6f3bf5 169 Gene3D G3DSA:3.90.950.10 1 168 3.3E-30 T 31-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like DFR85_11050 e5757aaa836db755ff757e7ccd6f3bf5 169 SUPERFAMILY SSF52972 1 166 7.41E-26 T 31-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like DFR85_00285 fc682a78093b4bd18c920d5a9b6e7096 251 Pfam PF01925 Sulfite exporter TauE/SafE 7 244 9.6E-40 T 31-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 DFR85_13415 c7dc5a6bbd8d7e74929d679e27bc6c56 521 Pfam PF07728 AAA domain (dynein-related subfamily) 223 399 3.5E-13 T 31-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 DFR85_13415 c7dc5a6bbd8d7e74929d679e27bc6c56 521 SMART SM00382 220 407 3.2E-6 T 31-10-2018 IPR003593 AAA+ ATPase domain DFR85_13415 c7dc5a6bbd8d7e74929d679e27bc6c56 521 SUPERFAMILY SSF52540 218 417 1.3E-18 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_13500 8524b70d08fa0566a17fa4a8c36ae3f6 228 Pfam PF03787 RAMP superfamily 25 204 1.8E-20 T 31-10-2018 IPR005537 CRISPR type III-associated RAMP protein DFR85_10285 b80c46664e486fd93e2ac631b9f20365 441 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 249 328 1.2E-17 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR85_05295 db9c4ab68111d8d4fa369d89c3ca8d5a 338 Gene3D G3DSA:3.40.50.1100 49 336 1.1E-77 T 31-10-2018 DFR85_05295 db9c4ab68111d8d4fa369d89c3ca8d5a 338 Gene3D G3DSA:3.40.50.1100 77 169 1.1E-77 T 31-10-2018 DFR85_05295 db9c4ab68111d8d4fa369d89c3ca8d5a 338 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 58 332 8.2E-58 T 31-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme DFR85_05295 db9c4ab68111d8d4fa369d89c3ca8d5a 338 SUPERFAMILY SSF53686 16 336 2.36E-71 T 31-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme DFR85_09400 1384d55538fd4155341bc58a76d606a8 101 Pfam PF02150 RNA polymerases M/15 Kd subunit 1 35 1.1E-10 T 31-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 DFR85_09400 1384d55538fd4155341bc58a76d606a8 101 SMART SM00661 2 57 2.4E-16 T 31-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 DFR85_07940 7a5af80779de0defcc1d785498ec086a 140 SMART SM00670 7 115 0.0058 T 31-10-2018 IPR002716 PIN domain DFR85_07940 7a5af80779de0defcc1d785498ec086a 140 SUPERFAMILY SSF88723 9 134 1.37E-16 T 31-10-2018 IPR029060 PIN-like domain superfamily DFR85_07940 7a5af80779de0defcc1d785498ec086a 140 Gene3D G3DSA:3.40.50.1010 8 135 4.5E-17 T 31-10-2018 DFR85_06985 3f48b2eeed192e7038e0d29543ae4832 195 Hamap MF_00234 Adenylate kinase [adkA]. 2 195 43.682 T 31-10-2018 IPR023477 Adenylate kinase AdkA GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 DFR85_06985 3f48b2eeed192e7038e0d29543ae4832 195 SUPERFAMILY SSF52540 5 192 8.93E-15 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_06985 3f48b2eeed192e7038e0d29543ae4832 195 Pfam PF13207 AAA domain 7 149 5.4E-30 T 31-10-2018 DFR85_06985 3f48b2eeed192e7038e0d29543ae4832 195 Gene3D G3DSA:3.40.50.300 1 195 3.9E-52 T 31-10-2018 DFR85_11700 e86bc42559212b33ae9abb530d896664 522 Gene3D G3DSA:1.20.1530.20 1 364 4.3E-34 T 31-10-2018 IPR038770 Sodium/solute symporter superfamily DFR85_11700 e86bc42559212b33ae9abb530d896664 522 Pfam PF00999 Sodium/hydrogen exchanger family 9 357 8.2E-23 T 31-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 DFR85_00090 07698aed6dfa1fd81065442f120878fe 211 SUPERFAMILY SSF52540 3 185 5.25E-17 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_00090 07698aed6dfa1fd81065442f120878fe 211 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 182 3.8E-9 T 31-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain DFR85_00090 07698aed6dfa1fd81065442f120878fe 211 Gene3D G3DSA:3.40.50.300 3 206 1.5E-16 T 31-10-2018 DFR85_12270 749dffb4957473be5ce1b2f897128d30 222 Pfam PF04434 SWIM zinc finger 112 128 2.6E-5 T 31-10-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 DFR85_04250 7a481be7c2793d057e2e464f15f146d8 489 SUPERFAMILY SSF51126 20 433 6.12E-5 T 31-10-2018 IPR011050 Pectin lyase fold/virulence factor DFR85_06680 5f7773259c1909b1421749f7be51871e 65 Pfam PF07754 Domain of unknown function (DUF1610) 16 39 6.2E-14 T 31-10-2018 IPR011668 Domain of unknown function DUF1610 DFR85_06680 5f7773259c1909b1421749f7be51871e 65 Pfam PF05191 Adenylate kinase, active site lid 15 45 2.3E-5 T 31-10-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 DFR85_14690 0af05419b88d7bf6da0ef0293d66a87a 137 Pfam PF11485 Protein of unknown function (DUF3211) 1 137 6.8E-45 T 31-10-2018 IPR021578 Protein of unknown function DUF3211 DFR85_14690 0af05419b88d7bf6da0ef0293d66a87a 137 Gene3D G3DSA:3.30.530.20 1 137 4.0E-52 T 31-10-2018 IPR023393 START-like domain superfamily DFR85_14430 b0cc47d7854c1fc6c4edcd1846272a11 124 Pfam PF05942 Archaeal PaREP1/PaREP8 family 19 115 1.4E-18 T 31-10-2018 IPR010268 Archaeal PaREP1 DFR85_04985 231991928f75d97ae801ef6655c10a64 131 Pfam PF05168 HEPN domain 10 49 5.4E-6 T 31-10-2018 IPR007842 HEPN domain DFR85_04985 231991928f75d97ae801ef6655c10a64 131 SUPERFAMILY SSF81593 12 52 2.12E-6 T 31-10-2018 DFR85_02255 69d5ff8c2002850f0563dd8b89e73430 176 Gene3D G3DSA:3.40.50.150 2 175 1.1E-41 T 31-10-2018 DFR85_02255 69d5ff8c2002850f0563dd8b89e73430 176 SUPERFAMILY SSF53335 29 167 2.81E-25 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase DFR85_02255 69d5ff8c2002850f0563dd8b89e73430 176 Pfam PF13847 Methyltransferase domain 29 131 4.9E-17 T 31-10-2018 IPR025714 Methyltransferase domain DFR85_11950 e3feca2918438c67756a910774bd14a4 155 Pfam PF10015 Uncharacterized protein conserved in archaea (DUF2258) 33 105 1.4E-23 T 31-10-2018 IPR017140 Uncharacterised conserved protein UCP037214 DFR85_03880 6c5e2bf47a86db1de23301adcf00f27d 186 Pfam PF03477 ATP cone domain 3 65 2.8E-11 T 31-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 DFR85_04430 2f29a8dcc028196098f66c7ce8ac35f2 122 Pfam PF02002 TFIIE alpha subunit 15 114 1.1E-8 T 31-10-2018 IPR024550 TFIIEalpha/SarR/Rpc3 HTH domain Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 DFR85_04430 2f29a8dcc028196098f66c7ce8ac35f2 122 Gene3D G3DSA:1.10.10.10 12 116 3.2E-24 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_04430 2f29a8dcc028196098f66c7ce8ac35f2 122 SUPERFAMILY SSF46785 14 118 7.01E-13 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_03885 7a2ed6ed290415b72c65719797429262 161 Pfam PF05942 Archaeal PaREP1/PaREP8 family 18 143 1.7E-26 T 31-10-2018 IPR010268 Archaeal PaREP1 DFR85_06635 e5f0e13e6afc97c8d0c3d9ed69721775 144 Pfam PF06146 Phosphate-starvation-inducible E 59 126 6.3E-7 T 31-10-2018 IPR020948 Phosphate-starvation-induced PsiE-like DFR85_07110 3f9dc3cfee10acab7e13136ecda415ac 245 Gene3D G3DSA:2.40.50.140 97 149 2.3E-34 T 31-10-2018 DFR85_07110 3f9dc3cfee10acab7e13136ecda415ac 245 SUPERFAMILY SSF75217 6 243 1.46E-23 T 31-10-2018 IPR029028 Alpha/beta knot methyltransferases DFR85_07110 3f9dc3cfee10acab7e13136ecda415ac 245 Pfam PF02598 Putative RNA methyltransferase 10 109 2.4E-11 T 31-10-2018 IPR003750 Putative RNA methyltransferase DFR85_07110 3f9dc3cfee10acab7e13136ecda415ac 245 Gene3D G3DSA:3.40.1280.10 12 242 2.3E-34 T 31-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal DFR85_08230 2b30d7608c9d7046bda52d44b0f4fca6 177 Pfam PF04967 HTH DNA binding domain 117 168 9.2E-20 T 31-10-2018 IPR007050 Bacterioopsin activator-type, HTH domain DFR85_00120 38090207dc61e81d639ecee95d5b6b74 424 Pfam PF02040 Arsenical pump membrane protein 6 421 4.9E-93 T 31-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 DFR85_00120 38090207dc61e81d639ecee95d5b6b74 424 PRINTS PR00758 Arsenical pump membrane protein signature 216 241 5.9E-55 T 31-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 DFR85_00120 38090207dc61e81d639ecee95d5b6b74 424 PRINTS PR00758 Arsenical pump membrane protein signature 146 170 5.9E-55 T 31-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 DFR85_00120 38090207dc61e81d639ecee95d5b6b74 424 PRINTS PR00758 Arsenical pump membrane protein signature 103 127 5.9E-55 T 31-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 DFR85_00120 38090207dc61e81d639ecee95d5b6b74 424 PRINTS PR00758 Arsenical pump membrane protein signature 361 386 5.9E-55 T 31-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 DFR85_00120 38090207dc61e81d639ecee95d5b6b74 424 PRINTS PR00758 Arsenical pump membrane protein signature 277 301 5.9E-55 T 31-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 DFR85_10315 242d228e5720586ea008642aef90aaef 96 SUPERFAMILY SSF46785 39 83 3.68E-5 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_05090 4361187bf6462ca6ac887b754f3daae1 156 Pfam PF05942 Archaeal PaREP1/PaREP8 family 35 147 1.2E-36 T 31-10-2018 IPR010268 Archaeal PaREP1 DFR85_05090 4361187bf6462ca6ac887b754f3daae1 156 Gene3D G3DSA:1.20.120.330 35 156 2.8E-38 T 31-10-2018 DFR85_11360 325ff4bf251f552d42c6cde5c82b9ffd 127 Gene3D G3DSA:1.10.10.10 14 117 3.5E-30 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_11360 325ff4bf251f552d42c6cde5c82b9ffd 127 SUPERFAMILY SSF46785 20 114 7.46E-15 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_11360 325ff4bf251f552d42c6cde5c82b9ffd 127 SMART SM00347 21 122 0.0021 T 31-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 DFR85_11360 325ff4bf251f552d42c6cde5c82b9ffd 127 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 22 96 1.9E-13 T 31-10-2018 IPR002831 Transcription regulator TrmB, N-terminal DFR85_10795 9f7ac5e6c516c7ded888cf378687e6af 351 Pfam PF04123 Domain of unknown function (DUF373) 9 337 1.2E-84 T 31-10-2018 IPR007254 Protein of unknown function DUF373 DFR85_01015 c95fd4884384da58b0d302bc6cb8a2ab 246 Pfam PF01988 VIT family 20 232 9.7E-43 T 31-10-2018 IPR008217 Ccc1 family DFR85_01390 1ea22f570be60a164ad5f05551e061e1 163 Pfam PF04027 Domain of unknown function (DUF371) 8 136 1.9E-45 T 31-10-2018 IPR007171 Protein of unknown function DUF371 DFR85_01390 1ea22f570be60a164ad5f05551e061e1 163 Gene3D G3DSA:2.60.120.630 2 144 2.5E-48 T 31-10-2018 IPR023131 Mth639-like domain superfamily DFR85_02875 25b59fe04b1ccff35182095fafaf1825 529 Gene3D G3DSA:1.10.4160.10 24 517 6.2E-95 T 31-10-2018 IPR038271 Purine-cytosine permease superfamily DFR85_02875 25b59fe04b1ccff35182095fafaf1825 529 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 40 476 9.6E-62 T 31-10-2018 IPR001248 Purine-cytosine permease GO:0016020|GO:0022857|GO:0055085 DFR85_15245 a1d23c5e70ac5ec63cce7e80256470f4 120 SUPERFAMILY SSF75169 1 96 3.83E-7 T 31-10-2018 IPR027396 DsrEFH-like DFR85_09715 f88c2c384bfc7f01748d91c2496f88f6 111 Pfam PF09943 Uncharacterized protein conserved in archaea (DUF2175) 6 104 3.3E-31 T 31-10-2018 IPR018686 Protein of unknown function DUF2175 DFR85_15270 f1bfab9057c98ebc78e040247a230e26 96 Pfam PF08734 GYD domain 4 91 1.2E-24 T 31-10-2018 IPR014845 Protein GYD/TTHA1554 DFR85_08945 b8c24d93590e178cd9e51cd4f0e41013 317 Pfam PF00953 Glycosyl transferase family 4 73 228 1.4E-33 T 31-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 DFR85_01820 a172ba08a6409975a72202d8bbcbc946 330 Pfam PF01061 ABC-2 type transporter 130 294 7.2E-11 T 31-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 DFR85_11145 544481adc04364e95e9242bc392e1432 753 Gene3D G3DSA:3.40.50.12610 464 547 1.7E-16 T 31-10-2018 DFR85_11145 544481adc04364e95e9242bc392e1432 753 Pfam PF02516 Oligosaccharyl transferase STT3 subunit 41 508 3.2E-22 T 31-10-2018 IPR003674 Oligosaccharyl transferase, STT3 subunit GO:0004576|GO:0006486|GO:0016020 DFR85_08225 775243a10572a79720e9e937cb175729 331 SUPERFAMILY SSF53383 12 318 1.63E-37 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase DFR85_08225 775243a10572a79720e9e937cb175729 331 Pfam PF00155 Aminotransferase class I and II 119 203 1.7E-11 T 31-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 DFR85_08225 775243a10572a79720e9e937cb175729 331 Gene3D G3DSA:3.90.1150.10 18 308 1.4E-54 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 DFR85_08225 775243a10572a79720e9e937cb175729 331 Gene3D G3DSA:3.40.640.10 28 225 1.4E-54 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 DFR85_08225 775243a10572a79720e9e937cb175729 331 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 179 188 - T 31-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 DFR85_10960 aadc1b3687df573996d1a58fbbad8a48 91 Gene3D G3DSA:1.20.120.970 1 91 2.0E-38 T 31-10-2018 DFR85_09675 6d3b9665315b694cb70900e9a2e05897 94 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 9 94 2.7E-12 T 31-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like DFR85_03370 fad82797ee96e3376d9d85cf00c00365 165 Pfam PF07680 TQO small subunit DoxA 30 153 4.6E-39 T 31-10-2018 IPR011636 Thiosulphate:quinone oxidoreductase small subunit DoxA KEGG: 00920+1.8.5.2|MetaCyc: PWY-5303 DFR85_07905 62d591b31e738b57f95868ba3e697879 323 Gene3D G3DSA:3.20.20.210 2 321 2.4E-39 T 31-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 DFR85_07905 62d591b31e738b57f95868ba3e697879 323 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 83 268 4.0E-21 T 31-10-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 DFR85_07905 62d591b31e738b57f95868ba3e697879 323 SUPERFAMILY SSF51726 7 311 5.36E-44 T 31-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 DFR85_12750 a97e325e85cd4d3fe983bef7d0194d59 269 Pfam PF05552 Conserved TM helix 13 54 1.7E-7 T 31-10-2018 IPR008910 Conserved TM helix DFR85_02490 98f18be7bb535a82c65c35d7ff71872d 64 Pfam PF06348 Protein of unknown function (DUF1059) 7 63 4.8E-21 T 31-10-2018 IPR009409 Protein of unknown function DUF1059 DFR85_12350 74e554731c053d872213dd42aef8ef38 353 Pfam PF02371 Transposase IS116/IS110/IS902 family 232 317 1.3E-23 T 31-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 DFR85_01840 e637fe248e9178734cc2791c7ba8eb0a 241 Pfam PF07758 Protein of unknown function (DUF1614) 59 233 1.5E-47 T 31-10-2018 IPR011672 Protein of unknown function DUF1614 DFR85_13570 e768819440459f0b3800bebd61f90675 437 SUPERFAMILY SSF160980 1 426 5.49E-29 T 31-10-2018 DFR85_12925 eb85ef22c2539276b7aa598f9abb8d1b 285 Pfam PF06157 Protein of unknown function (DUF973) 36 281 3.6E-54 T 31-10-2018 IPR009321 Protein of unknown function DUF973 DFR85_00535 c57c7fde425dbb4c4364366b60d915b7 199 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 155 1.4E-9 T 31-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain DFR85_00535 c57c7fde425dbb4c4364366b60d915b7 199 SUPERFAMILY SSF52540 2 164 1.42E-19 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase DFR85_00535 c57c7fde425dbb4c4364366b60d915b7 199 Gene3D G3DSA:3.40.50.300 3 190 1.6E-17 T 31-10-2018 DFR85_01060 b761d1fd3e3a471d177d5de97d3c448b 112 Pfam PF02416 mttA/Hcf106 family 8 53 1.9E-6 T 31-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 DFR85_09600 28ec34838c7bcbdd04d54ee254f7aa96 155 SUPERFAMILY SSF160527 85 142 3.53E-6 T 31-10-2018 DFR85_02105 8d0f7be9559875f6231767146335a9f3 227 SUPERFAMILY SSF48371 32 209 6.52E-6 T 31-10-2018 IPR016024 Armadillo-type fold DFR85_07850 3c7b0b54d2a4610862137d99725aea6b 95 Pfam PF12136 RNA polymerase Rpo13 subunit HTH domain 12 54 2.3E-10 T 31-10-2018 IPR021985 RNA polymerase Rpo13 subunit HTH domain DFR85_10085 66b8f1291f466569446444b1dee3dc53 221 SUPERFAMILY SSF56112 16 174 7.3E-13 T 31-10-2018 IPR011009 Protein kinase-like domain superfamily DFR85_10085 66b8f1291f466569446444b1dee3dc53 221 Gene3D G3DSA:1.10.510.10 91 202 2.7E-9 T 31-10-2018 DFR85_14810 7043cebc7812362a945249b54dba811d 345 Gene3D G3DSA:3.40.50.970 6 345 1.4E-109 T 31-10-2018 DFR85_14810 7043cebc7812362a945249b54dba811d 345 Pfam PF00676 Dehydrogenase E1 component 59 334 5.0E-72 T 31-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 DFR85_14810 7043cebc7812362a945249b54dba811d 345 SUPERFAMILY SSF52518 11 344 5.89E-89 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold DFR85_01800 0c3c9deb1a7a102582f7a3b7d48e2454 73 Gene3D G3DSA:3.40.30.10 2 73 2.7E-23 T 31-10-2018 DFR85_01800 0c3c9deb1a7a102582f7a3b7d48e2454 73 TIGRFAM TIGR02174 CXXU_selWTH: selT/selW/selH selenoprotein domain 4 72 6.0E-16 T 31-10-2018 IPR011893 Selenoprotein, Rdx-type DFR85_01800 0c3c9deb1a7a102582f7a3b7d48e2454 73 Pfam PF10262 Rdx family 4 72 5.6E-18 T 31-10-2018 IPR011893 Selenoprotein, Rdx-type DFR85_01800 0c3c9deb1a7a102582f7a3b7d48e2454 73 SUPERFAMILY SSF52833 3 71 6.49E-16 T 31-10-2018 IPR036249 Thioredoxin-like superfamily DFR85_05860 fc1d50d90b18e1f1e6a6f6f870fbf848 219 Gene3D G3DSA:1.20.58.220 7 215 4.1E-24 T 31-10-2018 IPR038078 PhoU-like domain superfamily DFR85_05860 fc1d50d90b18e1f1e6a6f6f870fbf848 219 Pfam PF01865 Protein of unknown function DUF47 10 215 2.4E-12 T 31-10-2018 IPR018445 Putative phosphate transport regulator DFR85_05025 5d4079e3187c841d328dcb155c6ecd82 176 Pfam PF04693 Archaeal putative transposase ISC1217 10 119 1.1E-30 T 31-10-2018 IPR006783 Transposase, ISC1217 DFR85_01130 62405062068ab837c18b2fb1236b7e4c 619 Gene3D G3DSA:1.50.10.10 256 619 3.7E-79 T 31-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 DFR85_01130 62405062068ab837c18b2fb1236b7e4c 619 SUPERFAMILY SSF48208 230 612 1.51E-104 T 31-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 DFR85_01130 62405062068ab837c18b2fb1236b7e4c 619 Pfam PF00723 Glycosyl hydrolases family 15 269 561 6.4E-11 T 31-10-2018 IPR011613 GH15-like domain Reactome: R-HSA-70221 DFR85_04890 a357a0e9352977f1d6d80fb04f4b35bb 189 Gene3D G3DSA:3.10.490.30 2 187 5.2E-47 T 31-10-2018 DFR85_12445 65329ea6ee5402be21586a43f1cf8431 197 Pfam PF14947 Winged helix-turn-helix 5 78 8.6E-23 T 31-10-2018 IPR038723 ArnR1-like, winged helix-turn-helix domain DFR85_12445 65329ea6ee5402be21586a43f1cf8431 197 Gene3D G3DSA:1.10.10.10 4 99 4.0E-26 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily DFR85_12445 65329ea6ee5402be21586a43f1cf8431 197 SUPERFAMILY SSF46785 6 91 3.27E-13 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily DFR85_13805 ba03389fb0feb96387593c909893a234 389 SUPERFAMILY SSF103473 25 381 3.66E-8 T 31-10-2018 IPR036259 MFS transporter superfamily DFR85_02920 d6a31598959451d84e9ec12dbe949b9a 429 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 260 338 2.9E-19 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR85_02920 d6a31598959451d84e9ec12dbe949b9a 429 Pfam PF01385 Probable transposase 190 295 1.7E-13 T 31-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 DFR85_02920 d6a31598959451d84e9ec12dbe949b9a 429 Pfam PF07282 Putative transposase DNA-binding domain 311 376 4.7E-22 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal DFR85_05135 8461521f8d51440ee2c136c409c3e75e 81 ProDom PD188822 UPF0330 AF1997 ST1125.1 AF1689 AF1478 C1_0043 PYRAB04040 PF1222 MM2475 MA1514 4 61 0.01 T 31-10-2018 IPR003847 Putative antitoxin DFR85_04240 c2878cba35046738f4e8b9e8afc9d5d2 323 Pfam PF00535 Glycosyl transferase family 2 5 154 4.0E-16 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 DFR85_04240 c2878cba35046738f4e8b9e8afc9d5d2 323 SUPERFAMILY SSF53448 3 279 1.56E-27 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_04240 c2878cba35046738f4e8b9e8afc9d5d2 323 Gene3D G3DSA:3.90.550.10 1 239 3.5E-30 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_12095 f726a157c0a9169a3eb8978f567a88d9 235 Gene3D G3DSA:1.10.3210.30 1 197 7.7E-28 T 31-10-2018 IPR038257 CRISPR-associated Cas3-type HD domain superfamily DFR85_05195 48d639fd350524daf4ad2b8a8e8d5d64 648 Gene3D G3DSA:2.60.40.10 480 584 1.9E-6 T 31-10-2018 IPR013783 Immunoglobulin-like fold DFR85_00655 185f947d34393f3e9f6bd7e3d1e16b03 371 Pfam PF13632 Glycosyl transferase family group 2 84 282 3.5E-18 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 DFR85_00655 185f947d34393f3e9f6bd7e3d1e16b03 371 SUPERFAMILY SSF53448 1 262 1.82E-38 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_00655 185f947d34393f3e9f6bd7e3d1e16b03 371 Gene3D G3DSA:3.90.550.10 1 202 2.9E-31 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases DFR85_14255 fdc79d99288f9493d7d8a09d977ef4fa 257 Pfam PF06053 Domain of unknown function (DUF929) 5 244 2.5E-75 T 31-10-2018 IPR009272 Protein of unknown function DUF929 DFR85_04325 ad3769503026cfaf10e5be52dce4987c 189 Pfam PF07760 Protein of unknown function (DUF1616) 22 167 1.5E-17 T 31-10-2018 IPR011674 Domain of unknown function DUF1616 DFR85_14440 bc0809e06737b1dc8453d812183d0a5f 412 PRINTS PR00173 Glutamate-aspartate symporter signature 50 70 6.1E-5 T 31-10-2018 DFR85_14440 bc0809e06737b1dc8453d812183d0a5f 412 PRINTS PR00173 Glutamate-aspartate symporter signature 369 389 6.1E-5 T 31-10-2018 DFR85_14440 bc0809e06737b1dc8453d812183d0a5f 412 PRINTS PR00173 Glutamate-aspartate symporter signature 172 194 6.1E-5 T 31-10-2018 DFR85_14440 bc0809e06737b1dc8453d812183d0a5f 412 PRINTS PR00173 Glutamate-aspartate symporter signature 81 106 6.1E-5 T 31-10-2018 DFR85_10745 f6f7298c9b2a02f759ccfaef1c129948 56 Pfam PF04758 Ribosomal protein S30 4 52 3.4E-14 T 31-10-2018 IPR006846 Ribosomal protein S30 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 DFR85_03565 640be4414d30e6f283a665f02d415670 173 Pfam PF06195 Protein of unknown function (DUF996) 30 163 1.3E-7 T 31-10-2018 IPR010397 Protein of unknown function DUF996 DFR85_00350 de377963f876c6416ae0fceecc5ac32e 268 Pfam PF06053 Domain of unknown function (DUF929) 30 264 1.6E-69 T 31-10-2018 IPR009272 Protein of unknown function DUF929 DFR85_03005 12f5c9fe104c1f3b28bd34f5aaf77169 618 Pfam PF13520 Amino acid permease 23 455 3.5E-43 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 DFR85_03005 12f5c9fe104c1f3b28bd34f5aaf77169 618 Gene3D G3DSA:1.20.1740.10 17 485 9.4E-58 T 31-10-2018 DFR85_10450 472995c9bbe0b065f45fe63207ff2070 143 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 1 141 9.0E-27 T 31-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 DFR85_10450 472995c9bbe0b065f45fe63207ff2070 143 SUPERFAMILY SSF51306 22 77 2.25E-6 T 31-10-2018 IPR036286 LexA/Signal peptidase-like superfamily DFR85_02535 b01ec2406f7ba41afc7fe1112d1fd24b 202 Pfam PF01774 UreD urease accessory protein 33 153 9.2E-11 T 31-10-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 DFR85_06155 0db577bcb7ddb772c652dfd45b53dc25 142 Pfam PF06157 Protein of unknown function (DUF973) 47 139 8.4E-8 T 31-10-2018 IPR009321 Protein of unknown function DUF973 DFR85_01555 65ed4dda37f604b9d5a6b3c1287ab51d 123 SUPERFAMILY SSF53146 1 92 5.41E-7 T 31-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily DFR85_07525 529cb6f9664ae1ddebad52e3d6bc78d5 116 Pfam PF04434 SWIM zinc finger 33 76 4.4E-4 T 31-10-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 DFR85_02070 de7ea68d72cbb747f64131c3a941d671 579 Pfam PF00361 Proton-conducting membrane transporter 93 310 1.1E-22 T 31-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 DFR85_12620 44e5c252e2be54198bf2cd35f072701b 259 Pfam PF04967 HTH DNA binding domain 198 250 4.4E-17 T 31-10-2018 IPR007050 Bacterioopsin activator-type, HTH domain DFR85_10975 12aff24279c95de5af2b16650fdd557e 99 Pfam PF16239 Domain of unknown function (DUF4898) 18 75 6.3E-7 T 31-10-2018 IPR032603 Protein of unknown function DUF4898 DFR85_09365 2cb797ffdd11306feeb8bc9c3a3cf4db 191 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 162 170 - T 31-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 DFR85_00970 248a59436c38a292abd20238e1568941 291 SUPERFAMILY SSF50182 130 198 3.2E-7 T 31-10-2018 IPR010920 LSM domain superfamily DFR85_00970 248a59436c38a292abd20238e1568941 291 Pfam PF00924 Mechanosensitive ion channel 88 227 9.9E-21 T 31-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 DFR85_00970 248a59436c38a292abd20238e1568941 291 SUPERFAMILY SSF82861 51 128 1.03E-8 T 31-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 DFR85_00570 31e53ffcd0435f8cd2e79fa14ec5d939 211 Gene3D G3DSA:3.40.50.12500 1 209 9.3E-23 T 31-10-2018 DFR85_13100 9e3e7c0db09c18f421e1f4384cc0080e 268 Pfam PF00188 Cysteine-rich secretory protein family 8 120 3.7E-4 T 31-10-2018 IPR014044 CAP domain DFR85_13100 9e3e7c0db09c18f421e1f4384cc0080e 268 Gene3D G3DSA:3.40.33.10 1 134 2.9E-11 T 31-10-2018 IPR035940 CAP superfamily DFR85_05380 1d7a2bb8d6c4ce39b5c448c87b718a39 406 Gene3D G3DSA:1.20.1530.20 17 404 4.1E-63 T 31-10-2018 IPR038770 Sodium/solute symporter superfamily DFR85_05380 1d7a2bb8d6c4ce39b5c448c87b718a39 406 Pfam PF00999 Sodium/hydrogen exchanger family 26 396 3.3E-44 T 31-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 DFR85_12265 5ad97700ff35a133b788af65958fb173 284 Pfam PF01925 Sulfite exporter TauE/SafE 15 272 2.9E-51 T 31-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 DFR85_10760 7ff7aff66a3cde0bf2a935ea9ee645e0 139 Pfam PF01886 Protein of unknown function DUF61 3 121 1.6E-22 T 31-10-2018 IPR002746 Uncharacterised protein family UPF0216 DFR85_03450 41ebbce636f3c906506ed03e40bbe69e 377 Pfam PF03595 Voltage-dependent anion channel 47 370 3.4E-24 T 31-10-2018 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 DFR85_15255 7f489fb6b5ea66c2616d3697a3b55a06 106 Pfam PF11494 Ta0938 1 104 2.1E-55 T 31-10-2018 IPR021585 Ta0938 DFR85_02080 067b823debb8ca130c30e3ee6049434d 213 ProDom PD037531 MEMBRANE HYDROGENASE SUBUNIT COMPONENT HYDROGENASE-4 E OXIDOREDUCTASE PRECURSOR SIGNAL 1.-.-.- 8 191 1.0E-32 T 31-10-2018 DFR85_15515 b8624baa12a8a7d79ff5bd54327ac176 211 Pfam PF04967 HTH DNA binding domain 148 200 6.2E-19 T 31-10-2018 IPR007050 Bacterioopsin activator-type, HTH domain DFR85_06090 27e9428b7d7b5792896ee28acbf6d7d2 290 Pfam PF02754 Cysteine-rich domain 148 238 2.1E-13 T 31-10-2018 IPR004017 Cysteine-rich domain DFR85_06090 27e9428b7d7b5792896ee28acbf6d7d2 290 Pfam PF02754 Cysteine-rich domain 3 83 4.0E-18 T 31-10-2018 IPR004017 Cysteine-rich domain DFR85_15565 b2dc78409c5ec9f313c6f281a74af3b2 110 SUPERFAMILY SSF75169 4 109 2.22E-17 T 31-10-2018 IPR027396 DsrEFH-like DFR85_13290 4c2c6f3d8dc56090102ff5c3e770cfcf 522 TIGRFAM TIGR02098 MJ0042_CXXC: MJ0042 family finger-like domain 64 92 3.2E-5 T 31-10-2018 IPR011723 Zinc finger/thioredoxin putative DFR85_00630 4d7a493a70e75fcf400652133a2cd79b 235 Pfam PF04981 NMD3 family 6 235 5.1E-42 T 31-10-2018 IPR007064 Nmd3, N-terminal DFR85_05370 91d59a7f567136afd8ca9fc124c57de6 271 Pfam PF06053 Domain of unknown function (DUF929) 16 269 6.4E-70 T 31-10-2018 IPR009272 Protein of unknown function DUF929 DFR85_12610 95c5799d06a66ddae0d1f8159e9ee05a 94 SUPERFAMILY SSF143011 22 90 6.41E-9 T 31-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily DFR85_12610 95c5799d06a66ddae0d1f8159e9ee05a 94 Gene3D G3DSA:3.30.2310.20 16 93 1.2E-7 T 31-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily DFR85_11225 23a8a04a1a82eda3cf7f9b3060312991 196 SUPERFAMILY SSF56112 30 160 1.51E-11 T 31-10-2018 IPR011009 Protein kinase-like domain superfamily DFR85_11365 55f652eb3c2223846ec2c16eb89bcd10 53 Pfam PF04945 YHS domain 6 47 2.1E-8 T 31-10-2018 IPR007029 YHS domain DFR85_03635 dc9e839d04cad0e65e15ccbf860d985c 121 Pfam PF07843 Protein of unknown function (DUF1634) 7 114 2.1E-28 T 31-10-2018 IPR012861 Protein of unknown function DUF1634 DFR85_03130 cf9521c7715c982e278ec21b53f9dd01 169 Pfam PF05942 Archaeal PaREP1/PaREP8 family 19 137 2.1E-26 T 31-10-2018 IPR010268 Archaeal PaREP1 DFR85_14170 b6fd69afaf51f529c08945ebef15ed5b 136 Pfam PF11485 Protein of unknown function (DUF3211) 2 136 1.8E-44 T 31-10-2018 IPR021578 Protein of unknown function DUF3211 DFR85_14170 b6fd69afaf51f529c08945ebef15ed5b 136 Gene3D G3DSA:3.30.530.20 1 136 4.9E-43 T 31-10-2018 IPR023393 START-like domain superfamily DFR85_15750 ccaabb10781f475fdd79ce53bbcbabc5 606 Pfam PF12801 4Fe-4S binding domain 248 274 3.6 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR85_15750 ccaabb10781f475fdd79ce53bbcbabc5 606 Pfam PF12801 4Fe-4S binding domain 155 198 6.6E-5 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain DFR85_08470 ff0e96634c911dc8f8911212e89a57f4 85 Pfam PF01998 Protein of unknown function DUF131 23 78 6.2E-17 T 31-10-2018 IPR002849 Protein of unknown function DUF131 DFR85_00085 13bb4b5e1f474fed186c4b8f93f37e1c 517 Gene3D G3DSA:1.20.1730.10 32 514 8.9E-29 T 31-10-2018 IPR038377 Sodium/glucose symporter superfamily