locus-tag	class	description
Ahos_0003	COG2154	pterin-4-alpha-carbinolamine dehydratase
Ahos_0008	COG0330	HflC and HflK could
Ahos_0013	COG0308	aminopeptidase N
Ahos_0021	COG1331	Highly conserved protein containing a thioredoxin domain
Ahos_0029	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Ahos_0030	COG0438	transferase activity, transferring glycosyl groups
Ahos_0034	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Ahos_0035	COG1024	Enoyl-CoA hydratase
Ahos_0039	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
Ahos_0044	COG1252	NADH dehydrogenase
Ahos_0046	COG1192	Involved in chromosome partitioning
Ahos_0049	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Ahos_0050	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
Ahos_0052	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
Ahos_0062	COG1111	helicase
Ahos_0062	COG1205	dead DEAH box helicase
Ahos_0065	COG1215	transferase activity, transferring glycosyl groups
Ahos_0077	COG2226	methyltransferase
Ahos_0078	COG0477	Major facilitator Superfamily
Ahos_0081	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Ahos_0081	COG0301	tRNA thio-modification
Ahos_0086	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Ahos_0087	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Ahos_0089	COG1013	pyruvate-flavodoxin oxidoreductase activity
Ahos_0090	COG0674	pyruvate-flavodoxin oxidoreductase activity
Ahos_0098	COG4555	ABC transporter
Ahos_0108	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Ahos_0114	COG0477	Major facilitator Superfamily
Ahos_0123	COG1215	transferase activity, transferring glycosyl groups
Ahos_0124	COG0489	protein tyrosine kinase activity
Ahos_0126	COG4946	Tricorn protease homolog
Ahos_0126	COG0823	Involved in the tonB-independent uptake of proteins
Ahos_0126	COG1506	peptidase
Ahos_0128	COG1573	uracil-dna glycosylase
Ahos_0134	COG0586	Pfam SNARE associated Golgi protein
Ahos_0137	COG1028	Short-chain dehydrogenase reductase Sdr
Ahos_0143	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Ahos_0143	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
Ahos_0166	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Ahos_0168	COG0095	Lipoate-protein ligase
Ahos_0172	COG0601	transmembrane transport
Ahos_0173	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Ahos_0174	COG0444	Belongs to the ABC transporter superfamily
Ahos_0175	COG4608	Belongs to the ABC transporter superfamily
Ahos_0186	COG0495	leucyl-tRNA aminoacylation
Ahos_0189	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Ahos_0192	COG2814	Major facilitator Superfamily
Ahos_0200	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Ahos_0217	COG1702	phosphate starvation-inducible protein PhoH
Ahos_0219	COG0375	protein maturation
Ahos_0222	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
Ahos_0230	COG1252	NADH dehydrogenase
Ahos_0234	COG0437	4 iron, 4 sulfur cluster binding
Ahos_0235	COG0243	molybdopterin cofactor binding
Ahos_0241	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Ahos_0245	COG2009	succinate dehydrogenase
Ahos_0255	COG2217	Heavy metal translocating P-type atpase
Ahos_0260	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Ahos_0261	COG4948	Mandelate Racemase Muconate Lactonizing
Ahos_0266	COG3387	PFAM Glycoside hydrolase 15-related
Ahos_0267	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Ahos_0271	COG2226	methyltransferase
Ahos_0272	COG0531	amino acid
Ahos_0275	COG1012	belongs to the aldehyde dehydrogenase family
Ahos_0285	COG2723	6-phospho-beta-galactosidase activity
Ahos_0288	COG1175	transmembrane transport
Ahos_0289	COG3833	ABC-type maltose transport systems, permease component
Ahos_0290	COG3842	ATPase activity
Ahos_0292	COG0459	protein refolding
Ahos_0296	COG1305	Transglutaminase-like
Ahos_0297	COG2308	Evidence 4 Homologs of previously reported genes of
Ahos_0300	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
Ahos_0300	COG0674	pyruvate-flavodoxin oxidoreductase activity
Ahos_0301	COG1013	pyruvate-flavodoxin oxidoreductase activity
Ahos_0303	COG0517	IMP dehydrogenase activity
Ahos_0303	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Ahos_0304	COG0372	Belongs to the citrate synthase family
Ahos_0306	COG1131	(ABC) transporter
Ahos_0309	COG1960	acyl-CoA dehydrogenase activity
Ahos_0311	COG0039	L-malate dehydrogenase activity
Ahos_0314	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Ahos_0316	COG0673	inositol 2-dehydrogenase activity
Ahos_0317	COG2271	Major facilitator Superfamily
Ahos_0318	COG2721	sulfolactate sulfo-lyase activity
Ahos_0319	COG2721	sulfolactate sulfo-lyase activity
Ahos_0321	COG1802	Transcriptional regulator
Ahos_0322	COG2814	Major facilitator Superfamily
Ahos_0323	COG1028	Short-chain dehydrogenase reductase Sdr
Ahos_0324	COG1012	belongs to the aldehyde dehydrogenase family
Ahos_0325	COG4948	Mandelate Racemase Muconate Lactonizing
Ahos_0326	COG3386	PFAM SMP-30 Gluconolaconase
Ahos_0330	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Ahos_0331	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Ahos_0337	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Ahos_0340	COG4608	Belongs to the ABC transporter superfamily
Ahos_0341	COG0444	Belongs to the ABC transporter superfamily
Ahos_0342	COG0601	transmembrane transport
Ahos_0388	COG1132	(ABC) transporter
Ahos_0389	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Ahos_0394	COG2002	toxin-antitoxin pair type II binding
Ahos_0411	COG2814	Major facilitator Superfamily
Ahos_0414	COG0519	Catalyzes the synthesis of GMP from XMP
Ahos_0417	COG1473	amidohydrolase
Ahos_0418	COG0402	S-adenosylhomocysteine deaminase activity
Ahos_0422	COG1953	Uracil, thiamine, allantoin
Ahos_0428	COG1505	serine-type exopeptidase activity
Ahos_0430	COG1522	sequence-specific DNA binding
Ahos_0431	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Ahos_0434	COG2814	Major facilitator Superfamily
Ahos_0435	COG0671	phosphoesterase, PA-phosphatase related
Ahos_0439	COG0531	amino acid
Ahos_0447	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Ahos_0450	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
Ahos_0452	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Ahos_0453	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Ahos_0455	COG2062	phosphohistidine phosphatase, SixA
Ahos_0457	COG2271	Major facilitator Superfamily
Ahos_0459	COG1473	amidohydrolase
Ahos_0462	COG1011	Hydrolase
Ahos_0464	COG0477	Major facilitator Superfamily
Ahos_0477	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Ahos_0482	COG1960	acyl-CoA dehydrogenase activity
Ahos_0483	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Ahos_0490	COG2222	sugar isomerase
Ahos_0491	COG0215	cysteine-tRNA ligase activity
Ahos_0492	COG1051	belongs to the nudix hydrolase family
Ahos_0494	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Ahos_0496	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Ahos_0498	COG1573	uracil-dna glycosylase
Ahos_0504	COG0475	glutathione-regulated potassium exporter activity
Ahos_0505	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Ahos_0509	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Ahos_0516	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
Ahos_0517	COG1881	PFAM PEBP family protein
Ahos_0518	COG2255	four-way junction helicase activity
Ahos_0519	COG2255	four-way junction helicase activity
Ahos_0520	COG0315	cyclic pyranopterin monophosphate synthase activity
Ahos_0531	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Ahos_0535	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Ahos_0536	COG1444	tRNA N-acetyltransferase activity
Ahos_0540	COG0589	response to stress
Ahos_0541	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Ahos_0542	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
Ahos_0542	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
Ahos_0543	COG0009	L-threonylcarbamoyladenylate synthase
Ahos_0544	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Ahos_0545	COG2379	hydroxypyruvate reductase
Ahos_0547	COG1321	iron dependent repressor
Ahos_0551	COG2226	methyltransferase
Ahos_0554	COG0303	'Molybdopterin
Ahos_0555	COG0746	molybdenum cofactor guanylyltransferase activity
Ahos_0558	COG0402	S-adenosylhomocysteine deaminase activity
Ahos_0564	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Ahos_0572	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Ahos_0574	COG1215	transferase activity, transferring glycosyl groups
Ahos_0575	COG1201	RNA secondary structure unwinding
Ahos_0577	COG4109	DRTGG domain
Ahos_0582	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Ahos_0583	COG1058	Belongs to the CinA family
Ahos_0583	COG1546	Belongs to the CinA family
Ahos_0586	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Ahos_0587	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Ahos_0588	COG0024	Methionine aminopeptidase
Ahos_0592	COG0561	phosphatase activity
Ahos_0593	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Ahos_0595	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Ahos_0599	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
Ahos_0600	COG0504	CTP synthase activity
Ahos_0603	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
Ahos_0609	COG2078	PFAM AMMECR1 domain protein
Ahos_0612	COG0717	Belongs to the dCTP deaminase family
Ahos_0613	COG1793	dna ligase
Ahos_0615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
Ahos_0620	COG0181	hydroxymethylbilane synthase activity
Ahos_0621	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Ahos_0622	COG0113	porphobilinogen synthase activity
Ahos_0624	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Ahos_0624	COG1648	precorrin-2 dehydrogenase activity
Ahos_0625	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Ahos_0627	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Ahos_0632	COG0017	Asparaginyl-tRNA synthetase
Ahos_0636	COG0028	Belongs to the TPP enzyme family
Ahos_0638	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Ahos_0639	COG0371	Dehydrogenase
Ahos_0640	COG1047	Peptidyl-prolyl cis-trans
Ahos_0641	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Ahos_0647	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
Ahos_0648	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Ahos_0650	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Ahos_0653	COG0528	UMP kinase activity
Ahos_0655	COG1355	regulation of microtubule-based process
Ahos_0656	COG0052	Belongs to the universal ribosomal protein uS2 family
Ahos_0658	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Ahos_0659	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Ahos_0660	COG0200	Binds to the 23S rRNA
Ahos_0662	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Ahos_0663	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Ahos_0664	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Ahos_0666	COG0432	Pfam Uncharacterised protein family UPF0047
Ahos_0668	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Ahos_0670	COG0417	DNA replication proofreading
Ahos_0676	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Ahos_0677	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Ahos_0680	COG3276	selenocysteine insertion sequence binding
Ahos_0682	COG0023	Translation Initiation Factor
Ahos_0684	COG0010	Belongs to the arginase family
Ahos_0685	COG0423	glycine-tRNA ligase activity
Ahos_0691	COG0163	prenyltransferase activity
Ahos_0692	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
Ahos_0695	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Ahos_0696	COG2815	serine threonine protein kinase
Ahos_0696	COG0515	serine threonine protein kinase
Ahos_0697	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Ahos_0698	COG0667	Aldo Keto reductase
Ahos_0707	COG1110	DNA topoisomerase II activity
Ahos_0708	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Ahos_0709	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
Ahos_0711	COG0557	exoribonuclease II activity
Ahos_0718	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Ahos_0721	COG1797	cobyrinic acid a,c-diamide synthase activity
Ahos_0724	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Ahos_0724	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Ahos_0726	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Ahos_0732	COG1201	RNA secondary structure unwinding
Ahos_0735	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Ahos_0736	COG2813	Specifically methylates the guanine in position
Ahos_0739	COG0051	transcription antitermination factor activity, RNA binding
Ahos_0741	COG0049	tRNA binding
Ahos_0746	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Ahos_0747	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Ahos_0748	COG0085	RNA polymerase activity
Ahos_0750	COG0281	malic enzyme
Ahos_0752	COG0105	UTP biosynthetic process
Ahos_0755	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Ahos_0757	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Ahos_0758	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Ahos_0760	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Ahos_0761	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Ahos_0763	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Ahos_0766	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Ahos_0767	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
Ahos_0769	COG0077	Prephenate dehydratase
Ahos_0769	COG1605	Chorismate mutase
Ahos_0777	COG1051	belongs to the nudix hydrolase family
Ahos_0777	COG1056	cytidyltransferase-related domain
Ahos_0778	COG1607	acyl-coa hydrolase
Ahos_0786	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
Ahos_0789	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
Ahos_0790	COG1129	ABC transporter
Ahos_0791	COG1980	fructose-bisphosphate aldolase activity
Ahos_0796	COG0459	protein refolding
Ahos_0799	COG0124	histidyl-tRNA synthetase
Ahos_0803	COG0343	queuine tRNA-ribosyltransferase activity
Ahos_0806	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Ahos_0808	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Ahos_0814	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Ahos_0818	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Ahos_0819	COG2264	protein methyltransferase activity
Ahos_0820	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
Ahos_0822	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Ahos_0823	COG0012	GTP binding
Ahos_0831	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Ahos_0832	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Ahos_0837	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Ahos_0838	COG0546	phosphoglycolate phosphatase activity
Ahos_0841	COG0473	3-isopropylmalate dehydrogenase activity
Ahos_0842	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Ahos_0847	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Ahos_0848	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Ahos_0849	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Ahos_0850	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Ahos_0851	COG0255	Belongs to the universal ribosomal protein uL29 family
Ahos_0854	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Ahos_0855	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Ahos_0857	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Ahos_0859	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Ahos_0860	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Ahos_0864	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Ahos_0866	COG0200	Binds to the 23S rRNA
Ahos_0867	COG0201	protein transport
Ahos_0871	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Ahos_0880	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Ahos_0883	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Ahos_0884	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Ahos_0887	COG0189	ligase activity
Ahos_0888	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Ahos_0889	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Ahos_0890	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Ahos_0893	COG0114	fumarate hydratase activity
Ahos_0894	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Ahos_0896	COG0517	IMP dehydrogenase activity
Ahos_0896	COG0516	GMP reductase activity
Ahos_0900	COG0149	triose-phosphate isomerase activity
Ahos_0903	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Ahos_0904	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Ahos_0910	COG2815	serine threonine protein kinase
Ahos_0910	COG0515	serine threonine protein kinase
Ahos_0915	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Ahos_0915	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Ahos_0916	COG0517	IMP dehydrogenase activity
Ahos_0918	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Ahos_0919	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
Ahos_0920	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
Ahos_0925	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Ahos_0930	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Ahos_0936	COG0543	2 iron, 2 sulfur cluster binding
Ahos_0936	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Ahos_0939	COG3264	Mechanosensitive ion channel
Ahos_0939	COG1196	nuclear chromosome segregation
Ahos_0945	COG0312	modulator of DNA gyrase
Ahos_0949	COG0037	tRNA processing
Ahos_0964	COG2409	Drug exporters of the RND superfamily
Ahos_0971	COG0489	protein tyrosine kinase activity
Ahos_0974	COG1280	lysine exporter protein (LysE YggA)
Ahos_0979	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Ahos_0981	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Ahos_0991	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
Ahos_0992	COG3830	Belongs to the UPF0237 family
Ahos_0993	COG2848	UPF0210 protein
Ahos_0995	COG0438	transferase activity, transferring glycosyl groups
Ahos_1004	COG1584	GPR1 FUN34 yaaH family protein
Ahos_1005	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Ahos_1008	COG2814	Major facilitator Superfamily
Ahos_1013	COG0438	transferase activity, transferring glycosyl groups
Ahos_1018	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Ahos_1020	COG1131	(ABC) transporter
Ahos_1022	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
Ahos_1032	COG0501	Belongs to the peptidase M48B family
Ahos_1036	COG0477	Major facilitator Superfamily
Ahos_1039	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
Ahos_1042	COG1592	Rubrerythrin
Ahos_1049	COG0450	alkyl hydroperoxide reductase
Ahos_1051	COG1215	transferase activity, transferring glycosyl groups
Ahos_1053	COG0351	phosphomethylpyrimidine kinase
Ahos_1053	COG0352	thiamine-phosphate diphosphorylase activity
Ahos_1054	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Ahos_1055	COG0123	including yeast histone deacetylase and acetoin utilization protein
Ahos_1058	COG1234	tRNA 3'-trailer cleavage
Ahos_1063	COG0463	Glycosyl transferase, family 2
Ahos_1064	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Ahos_1066	COG0501	Belongs to the peptidase M48B family
Ahos_1067	COG1063	alcohol dehydrogenase
Ahos_1071	COG0519	Catalyzes the synthesis of GMP from XMP
Ahos_1071	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Ahos_1072	COG0501	Belongs to the peptidase M48B family
Ahos_1073	COG0516	GMP reductase activity
Ahos_1073	COG0517	IMP dehydrogenase activity
Ahos_1076	COG1830	Aldolase
Ahos_1080	COG0405	Gamma-glutamyltransferase
Ahos_1083	COG1444	tRNA N-acetyltransferase activity
Ahos_1087	COG0589	response to stress
Ahos_1090	COG0864	Transcriptional regulator
Ahos_1092	COG0460	homoserine dehydrogenase
Ahos_1093	COG0109	protoheme IX farnesyltransferase activity
Ahos_1095	COG1024	Enoyl-CoA hydratase
Ahos_1103	COG1250	3-hydroxyacyl-CoA dehydrogenase
Ahos_1105	COG0189	ligase activity
Ahos_1106	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Ahos_1107	COG0505	Belongs to the CarA family
Ahos_1108	COG0165	Argininosuccinate lyase
Ahos_1109	COG0137	argininosuccinate synthase activity
Ahos_1111	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Ahos_1112	COG0151	Belongs to the GarS family
Ahos_1113	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Ahos_1114	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Ahos_1115	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Ahos_1116	COG0047	phosphoribosylformylglycinamidine synthase activity
Ahos_1117	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Ahos_1118	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Ahos_1118	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Ahos_1119	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Ahos_1127	COG0284	orotidine-5'-phosphate decarboxylase activity
Ahos_1129	COG0540	Belongs to the ATCase OTCase family
Ahos_1130	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
Ahos_1132	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Ahos_1133	COG0167	dihydroorotate dehydrogenase activity
Ahos_1136	COG2095	MarC family integral membrane protein
Ahos_1137	COG1522	sequence-specific DNA binding
Ahos_1140	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Ahos_1141	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Ahos_1142	COG2151	metal-sulfur cluster biosynthetic enzyme
Ahos_1144	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Ahos_1146	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Ahos_1147	COG0107	imidazoleglycerol-phosphate synthase activity
Ahos_1148	COG0131	Imidazoleglycerol-phosphate dehydratase
Ahos_1150	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Ahos_1151	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Ahos_1153	COG0495	leucyl-tRNA aminoacylation
Ahos_1154	COG2096	Adenosyltransferase
Ahos_1155	COG0037	tRNA processing
Ahos_1157	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
Ahos_1160	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
Ahos_1162	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
Ahos_1163	COG0546	phosphoglycolate phosphatase activity
Ahos_1164	COG0028	Belongs to the TPP enzyme family
Ahos_1169	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
Ahos_1170	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
Ahos_1176	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
Ahos_1180	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Ahos_1186	COG0417	DNA replication proofreading
Ahos_1188	COG1260	myo-inositol-1-phosphate synthase
Ahos_1189	COG1007	ATP synthesis coupled electron transport
Ahos_1190	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Ahos_1191	COG0713	ATP synthesis coupled electron transport
Ahos_1193	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Ahos_1194	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Ahos_1195	COG0649	NAD binding
Ahos_1196	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Ahos_1202	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Ahos_1208	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Ahos_1209	COG0723	plastoquinol--plastocyanin reductase activity
Ahos_1211	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Ahos_1212	COG0083	homoserine kinase activity
Ahos_1213	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Ahos_1214	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Ahos_1215	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Ahos_1216	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
Ahos_1217	COG1605	Chorismate mutase
Ahos_1217	COG0077	Prephenate dehydratase
Ahos_1218	COG3958	Transketolase
Ahos_1219	COG3959	Transketolase, thiamine diphosphate binding domain
Ahos_1226	COG0539	negative regulation of cytoplasmic translation
Ahos_1236	COG0067	glutamate synthase
Ahos_1237	COG0069	glutamate synthase activity
Ahos_1240	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
Ahos_1252	COG1185	polyribonucleotide nucleotidyltransferase activity
Ahos_1258	COG0300	oxidoreductase activity
Ahos_1265	COG0535	radical SAM domain protein
Ahos_1266	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
Ahos_1267	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Ahos_1267	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Ahos_1269	COG0318	PFAM AMP-dependent synthetase and ligase
Ahos_1274	COG0302	gtp cyclohydrolase
Ahos_1276	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Ahos_1279	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Ahos_1292	COG0552	protein localization to endoplasmic reticulum
Ahos_1295	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Ahos_1299	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Ahos_1302	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Ahos_1306	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Ahos_1309	COG0126	phosphoglycerate kinase activity
Ahos_1321	COG0396	ATPase activity
Ahos_1325	COG0509	glycine decarboxylation via glycine cleavage system
Ahos_1326	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Ahos_1327	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Ahos_1328	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Ahos_1335	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Ahos_1336	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Ahos_1339	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Ahos_1346	COG0525	valine-tRNA ligase activity
Ahos_1347	COG0436	Aminotransferase
Ahos_1348	COG0134	indole-3-glycerol-phosphate synthase activity
Ahos_1349	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Ahos_1349	COG0512	Glutamine amidotransferase of anthranilate synthase
Ahos_1350	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Ahos_1351	COG0135	phosphoribosylanthranilate isomerase activity
Ahos_1352	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Ahos_1353	COG0159	tryptophan synthase activity
Ahos_1354	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
Ahos_1355	COG1254	Belongs to the acylphosphatase family
Ahos_1358	COG0574	Belongs to the PEP-utilizing enzyme family
Ahos_1358	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Ahos_1361	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Ahos_1363	COG0527	aspartate kinase activity
Ahos_1364	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Ahos_1367	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Ahos_1374	COG0459	protein refolding
Ahos_1379	COG0018	arginyl-trna synthetase
Ahos_1381	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Ahos_1384	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Ahos_1385	COG0252	asparaginase activity
Ahos_1391	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
Ahos_1401	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
Ahos_1401	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
Ahos_1404	COG0154	amidase activity
Ahos_1405	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Ahos_1406	COG1324	tolerance protein
Ahos_1408	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Ahos_1413	COG1110	DNA topoisomerase II activity
Ahos_1415	COG0514	ATP-dependent DNA helicase (RecQ)
Ahos_1422	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Ahos_1423	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Ahos_1425	COG2084	Dehydrogenase
Ahos_1427	COG1028	Short-chain dehydrogenase reductase Sdr
Ahos_1429	COG0528	UMP kinase activity
Ahos_1431	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Ahos_1443	COG2814	Major facilitator Superfamily
Ahos_1450	COG0426	domain, Protein
Ahos_1450	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Ahos_1458	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Ahos_1459	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Ahos_1462	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Ahos_1467	COG0004	ammonium transporteR
Ahos_1469	COG2235	arginine
Ahos_1473	COG0438	transferase activity, transferring glycosyl groups
Ahos_1475	COG0589	response to stress
Ahos_1479	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Ahos_1481	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Ahos_1484	COG0045	succinate-CoA ligase (ADP-forming) activity
Ahos_1488	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
Ahos_1489	COG1078	dGTPase activity
Ahos_1496	COG1832	CoA-binding protein
Ahos_1497	COG0179	Fumarylacetoacetate (FAA) hydrolase
Ahos_1501	COG0530	calcium, potassium:sodium antiporter activity
Ahos_1503	COG3386	PFAM SMP-30 Gluconolaconase
Ahos_1505	COG1695	Transcriptional regulator
Ahos_1512	COG0697	spore germination
Ahos_1514	COG2814	Major facilitator Superfamily
Ahos_1515	COG1335	isochorismatase
Ahos_1518	COG1733	regulation of RNA biosynthetic process
Ahos_1520	COG2002	toxin-antitoxin pair type II binding
Ahos_1537	COG3511	phospholipase C
Ahos_1539	COG1122	ATPase activity
Ahos_1557	COG0813	purine-nucleoside phosphorylase activity
Ahos_1558	COG0730	response to heat
Ahos_1560	COG0531	amino acid
Ahos_1564	COG0535	radical SAM domain protein
Ahos_1569	COG0644	oxidoreductase
Ahos_1571	COG2086	electron transfer activity
Ahos_1572	COG1960	acyl-CoA dehydrogenase activity
Ahos_1573	COG0243	molybdopterin cofactor binding
Ahos_1581	COG1373	ATPase (AAA superfamily
Ahos_1609	COG0463	Glycosyl transferase, family 2
Ahos_1615	COG1088	dTDP-glucose 4,6-dehydratase activity
Ahos_1623	COG1373	ATPase (AAA superfamily
Ahos_1627	COG1914	H( )-stimulated, divalent metal cation uptake system
Ahos_1628	COG2814	Major facilitator Superfamily
Ahos_1629	COG0589	response to stress
Ahos_1635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Ahos_1646	COG0477	Major facilitator Superfamily
Ahos_1653	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Ahos_1658	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Ahos_1660	COG0805	protein transport
Ahos_1670	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Ahos_1681	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Ahos_1682	COG0095	Lipoate-protein ligase
Ahos_1684	COG0509	glycine decarboxylation via glycine cleavage system
Ahos_1685	COG0095	Lipoate-protein ligase
Ahos_1686	COG0509	glycine decarboxylation via glycine cleavage system
Ahos_1691	COG2048	Heterodisulfide reductase, subunit B
Ahos_1694	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Ahos_1697	COG0425	Belongs to the sulfur carrier protein TusA family
Ahos_1698	COG2210	Belongs to the sulfur carrier protein TusA family
Ahos_1700	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Ahos_1704	COG0123	including yeast histone deacetylase and acetoin utilization protein
Ahos_1708	COG1720	tRNA m6t6A37 methyltransferase activity
Ahos_1714	COG1063	alcohol dehydrogenase
Ahos_1715	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Ahos_1717	COG3383	formate dehydrogenase (NAD+) activity
Ahos_1722	COG2814	Major facilitator Superfamily
Ahos_1722	COG0477	Major facilitator Superfamily
Ahos_1725	COG0531	amino acid
Ahos_1733	COG1131	(ABC) transporter
Ahos_1757	COG1401	restriction endodeoxyribonuclease activity
Ahos_1759	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Ahos_1782	COG3842	ATPase activity
Ahos_1792	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Ahos_1807	COG1720	tRNA m6t6A37 methyltransferase activity
Ahos_1812	COG0708	Exodeoxyribonuclease III
Ahos_1814	COG0602	queuosine metabolic process
Ahos_1828	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Ahos_1836	COG1968	undecaprenyl-diphosphatase activity
Ahos_1843	COG1489	DNA binding
Ahos_1847	COG0656	L-ascorbic acid biosynthetic process
Ahos_1868	COG0531	amino acid
Ahos_1872	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Ahos_1892	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
Ahos_1894	COG3387	PFAM Glycoside hydrolase 15-related
Ahos_1896	COG0477	Major facilitator Superfamily
Ahos_1901	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Ahos_1931	COG2271	Major facilitator Superfamily
Ahos_1941	COG0308	aminopeptidase N
Ahos_1949	COG1013	pyruvate-flavodoxin oxidoreductase activity
Ahos_1950	COG0674	pyruvate-flavodoxin oxidoreductase activity
Ahos_1953	COG0531	amino acid
Ahos_1955	COG0277	FAD linked oxidase domain protein
Ahos_1961	COG4152	abc transporter atp-binding protein
Ahos_1984	COG1131	(ABC) transporter
Ahos_1988	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
Ahos_2000	COG4139	cobalamin transport
Ahos_2001	COG1121	(ABC) transporter
Ahos_2002	COG2875	Belongs to the precorrin methyltransferase family
Ahos_2012	COG3383	formate dehydrogenase (NAD+) activity
Ahos_2022	COG1131	(ABC) transporter
Ahos_2025	COG0071	Belongs to the small heat shock protein (HSP20) family
Ahos_2026	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Ahos_2050	COG2860	membrane
Ahos_2051	COG0697	spore germination
Ahos_2057	COG1139	Iron-sulfur cluster binding protein
Ahos_2063	COG0045	succinate-CoA ligase (ADP-forming) activity
Ahos_2063	COG1042	CoA-binding domain protein
Ahos_2063	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Ahos_2064	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Ahos_2065	COG0531	amino acid
Ahos_2066	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Ahos_2067	COG1063	alcohol dehydrogenase
Ahos_2069	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Ahos_2073	COG1129	ABC transporter
Ahos_2077	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Ahos_2078	COG0066	3-isopropylmalate dehydratase activity
Ahos_2079	COG0778	Nitroreductase
Ahos_2088	COG0708	Exodeoxyribonuclease III
Ahos_2091	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Ahos_2096	COG0157	Belongs to the NadC ModD family
Ahos_2097	COG0519	Catalyzes the synthesis of GMP from XMP
Ahos_2099	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
Ahos_2103	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
Ahos_2105	COG1515	deoxyribonuclease V activity
Ahos_2106	COG1335	isochorismatase
Ahos_2108	COG0450	alkyl hydroperoxide reductase
Ahos_2111	COG0372	Belongs to the citrate synthase family
Ahos_2115	COG4581	dead DEAH box helicase
Ahos_2117	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Ahos_2119	COG0439	Biotin carboxylase
Ahos_2125	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Ahos_2142	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
Ahos_2143	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
Ahos_2146	COG0569	domain protein
Ahos_2146	COG0189	ligase activity
Ahos_2147	COG1522	sequence-specific DNA binding
Ahos_2150	COG1446	asparaginase
Ahos_2157	COG0647	UMP catabolic process
Ahos_2158	COG1053	succinate dehydrogenase
Ahos_2160	COG2048	Heterodisulfide reductase, subunit B
Ahos_2162	COG2304	oxidoreductase activity
Ahos_2163	COG0714	Associated with various cellular activities
Ahos_2166	COG0303	'Molybdopterin
Ahos_2167	COG0083	homoserine kinase activity
Ahos_2168	COG0626	cystathionine gamma-synthase activity
Ahos_2176	COG0183	Belongs to the thiolase family
Ahos_2177	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Ahos_2181	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Ahos_2184	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
Ahos_2188	COG0351	phosphomethylpyrimidine kinase
Ahos_2195	COG1131	(ABC) transporter
Ahos_2201	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Ahos_2207	COG0720	synthase
Ahos_2210	COG0492	ferredoxin-NADP+ reductase activity
Ahos_2212	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Ahos_2215	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
Ahos_2218	COG0071	Belongs to the small heat shock protein (HSP20) family
Ahos_2223	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Ahos_2227	COG1648	precorrin-2 dehydrogenase activity
Ahos_2227	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Ahos_2233	COG0174	glutamine synthetase
Ahos_2234	COG1063	alcohol dehydrogenase
Ahos_2235	COG0430	RNA-3'-phosphate cyclase activity
Ahos_2237	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Ahos_2238	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Ahos_2239	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Ahos_2241	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Ahos_2256	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Ahos_2258	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Ahos_2259	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Ahos_2263	COG0456	acetyltransferase
Ahos_2264	COG0469	pyruvate kinase activity
Ahos_2270	COG0297	glycogen (starch) synthase activity
Ahos_2276	COG1250	3-hydroxyacyl-CoA dehydrogenase
Ahos_2277	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
Ahos_2283	COG1063	alcohol dehydrogenase
Ahos_2285	COG0154	amidase activity
Ahos_2287	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Ahos_2288	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Ahos_2288	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Ahos_2299	COG0735	belongs to the Fur family
Ahos_2300	COG1957	nucleoside hydrolase
Ahos_2305	COG2062	phosphohistidine phosphatase, SixA
Ahos_2308	COG3118	belongs to the thioredoxin family
Ahos_2319	COG0492	ferredoxin-NADP+ reductase activity
Ahos_2322	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Ahos_2326	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
Ahos_2328	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
Ahos_2332	COG0561	phosphatase activity
Ahos_2334	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Ahos_2335	COG0537	adenosine 5'-monophosphoramidase activity
Ahos_2337	COG0494	nUDIX hydrolase
Ahos_2341	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Ahos_2342	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Ahos_2342	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Ahos_2353	COG0538	isocitrate dehydrogenase activity